ABCD#1234 Johannes Jäger Johannes Jaeger Pharmakologische Wirkstoffe für das Nervensystem 94 7 AA PAT SOURCE 1..7 ORGANISM Homo sapiens MOL_TYPE protein REGION 1..7 NOTE circular peptide SITE 1 NOTE D-Alanine SITE 2 NOTE D-Glutamic acid SITE 4 NOTE Nle SITE 6 NOTE D-Methionine SITE 7 NOTE D-Norleucine AEKXGMX 6 AA PAT SOURCE 1..6 ORGANISM Homo sapiens MOL_TYPE protein SITE 1 NOTE the N-terminus is acetylated SITE 4 NOTE 6-amino-7-(1H-indol-3-yl)-5-oxoheptanoic acid SITE 6 NOTE the C-terminus is methylated VAFXGK 4 AA PAT SOURCE 1..4 ORGANISM Homo sapiens MOL_TYPE protein SITE 1 NOTE the N-terminus is acetylated SITE 4 NOTE C-terminus linked via a glutaraldehyde bridge to dipeptide GK VAFW 5 AA PAT SOURCE 1..5 ORGANISM Homo sapiens MOL_TYPE protein REGION >5 NOTE The entire sequence of amino acids 1-5 can be repeated one or more times VARIANT 5 NOTE X can be any amino acid GGGGX 12 DNA PAT source 1..12 organism synthetic construct mol_type other DNA misc_feature 12 note cytosine attached to a C3 spacer, which is joined to another nucleic acid atgcatgcatgc 12 DNA PAT source 1..12 organism synthetic construct mol_type other DNA misc_feature 1 note cytosine attached to a C3 spacer, which is joined to another nucleic acid cggcatgcatgc 25 DNA PAT source 1..25 organism Mus musculus mol_type genomic DNA atgcatgcatgcvcggcatgcatgc 12 DNA PAT source 1..12 organism synthetic construct mol_type other DNA misc_feature 12 note cytosine is linked to a C3 spacer, which is linked to 5&apos;-end of another nucleic acid atgcatgcatgc 12 DNA PAT source 1..12 organism synthetic construct mol_type other DNA misc_feature 1 note cytosine is linked to a C3 spacer, which is linked to 3&apos;-end of another nucleic acid cggcatgcatgc 18 DNA PAT source 1..18 organism Homo sapiens mol_type genomic DNA modified_base 11 mod_base OTHER note abasic site gagcattgacntaaggct 30 DNA PAT source 1..30 organism synthetic construct mol_type other DNA note GNA sequence modified_base 1..30 mod_base OTHER note 2,3-dihydroxypropyl nucleosides (glycol nucleic acids) tagttcattgactaaggctccccattgact 10 DNA PAT source 1..10 organism synthetic construct mol_type other DNA aatgccggag 10 DNA PAT source 1..10 organism synthetic construct mol_type other DNA aatgccggak 10 DNA PAT source 1..10 organism synthetic construct mol_type other DNA aatgccggac 10 DNA PAT source 1..10 organism Homo sapiens mol_type genomic DNA aatgttggac 15 DNA PAT source 1..15 organism synthetic construct mol_type other DNA nngkngkngkagvcr 7 AA PAT SOURCE 1..7 ORGANISM Homo sapiens MOL_TYPE protein VARIANT 1 NOTE X can be any amino acid XYEKGJL 30 DNA PAT source 1..30 organism synthetic construct mol_type other DNA misc_feature 1 note This sequence is one of four branches of a branched polynucleotide cacacaaaaaaaaaaaaaaaaaaaaaaaaa 28 DNA PAT source 1..28 organism synthetic construct mol_type other DNA misc_feature 1 note This sequence is one of four branches of a branched polynucleotide. cacataggcatctcctagtgcaggaaga 75 RNA PAT source 1..75 organism Homo sapiens mol_type tRNA modified_base 39 mod_base p modified_base 54 mod_base p gcggatttagctcagctgggagagcgccagactgaatanctggagtcctgtgtncgatccacagaattcgcacca 44 DNA PAT source 1..44 organism Homo sapiens mol_type genomic DNA gatcattttttatattttttatattttttatattttttatgtac 44 DNA PAT source 1..44 organism Homo sapiens mol_type genomic DNA repeat_region 5..40 rpt_type tandem rpt_unit_seq atacgcact attcatacgcactatacgcactatacgcactatacgcactgtac 44 DNA PAT source 1..44 organism Homo sapiens mol_type genomic DNA repeat_region 5..40 rpt_type tandem rpt_unit_seq atacgcact gatcatacgcactatacgcactatacgcactatacgcactgtac 12 DNA PAT source 1..12 organism synthetic construct mol_type other DNA misc_difference 5..8 note A nucleotide in any of positions 5-8 may be replaced with inosine or pseudouridine. modified_base 5..8 mod_base OTHER note i or p gatcaaaagtac 74 AA PAT SOURCE 1..74 ORGANISM synthetic construct MOL_TYPE protein VARIANT 1..8 NOTE X can be any amino acid VARIANT 10..19 NOTE X can be any amino acid VARIANT 21..48 NOTE X can be any amino acid VARIANT 50..68 NOTE X can be any amino acid VARIANT 70..74 NOTE X can be any amino acid XXXXXXXXDXXXXXXXXXXFXXXXXXXXXXXXXXXXXXXXXXXXXXXXAXXXXXXXXXXXXXXXXXXXGXXXXX 4 AA PAT SOURCE 1..4 ORGANISM synthetic construct MOL_TYPE protein SITE 1..4 NOTE This sequence is one part of a branched amino acid sequence SITE 4 NOTE Leu is linked to another sequence RISL 4 AA PAT SOURCE 1..4 ORGANISM synthetic construct MOL_TYPE protein SITE 1..4 NOTE This sequence is one part of a branched amino acid sequence SITE 3 NOTE The side chain of Lysine is linked via an amide linkage to another sequence SITE 4 NOTE The side chain of Lysine is linked via an amide linkage to another sequence LLKK 6 AA PAT SOURCE 1..6 ORGANISM synthetic construct MOL_TYPE protein SITE 1..6 NOTE This sequence is one part of a branched amino acid sequence SITE 6 NOTE Ala is linked to another sequence IPACTA 6 AA PAT SOURCE 1..6 ORGANISM synthetic construct MOL_TYPE protein SITE 1..6 NOTE This sequence is one part of a branched amino acid sequence SITE 6 NOTE The side chain of Lysine is linked via an amide linkage to another sequence FRAGGK 5 AA PAT SOURCE 1..5 ORGANISM synthetic construct MOL_TYPE protein SITE 1..5 NOTE This sequence is one part of a branched amino acid sequence SITE 5 NOTE Ala is linked to another sequence HQYFA 8 AA PAT SOURCE 1..8 ORGANISM synthetic construct MOL_TYPE protein SITE 1..8 NOTE This sequence is one part of a branched amino acid sequence SITE 5 NOTE The side chain of Lysine is linked via an amide linkage to another sequence SITE 6 NOTE The side chain of Lysine is linked via an amide linkage to another sequence SITE 7 NOTE The side chain of Lysine is linked via an amide linkage to another sequence ATFGKKKA 8 AA PAT SOURCE 1..8 ORGANISM Homo sapiens MOL_TYPE protein SITE 5 NOTE The side chain of Lysine is linked via an amide linkage to another sequence DGSAKKKK 5 AA PAT SOURCE 1..5 ORGANISM Homo sapiens MOL_TYPE protein SITE 5 NOTE Gly is linked to another sequence AASHG 13 DNA PAT source 1..13 organism Homo sapiens mol_type genomic DNA atcgcaattggcc 13 DNA PAT source 1..13 organism Homo sapiens mol_type genomic DNA ggccaattgcgat 58 DNA PAT source 1..58 organism Homo sapiens mol_type genomic DNA tagttcattgactaaggctccccattgactaaggcgactagcattgactaaggcaagc 16 DNA PAT source 1..16 organism synthetic construct mol_type other DNA modified_base 1..16 mod_base OTHER note N-(2-aminoethyl) glycine nucleosides (PNA) modified_base 6 mod_base OTHER note N-(2-aminoethyl) glycine 5-nitroindole or N-(2-aminoethyl) glycine 3-nitroindole cgcctnagtcaatggg 25 DNA PAT source 1..25 organism Homo sapiens mol_type genomic DNA atcgggatcgcatattcgattggcc 25 DNA PAT source 1..25 organism Homo sapiens mol_type genomic DNA ggccaatatggcttgcgatcccgat 20 RNA PAT source 1..20 organism synthetic construct mol_type other DNA misc_feature 1 note The 5' oxygen of the thymidine is attached through the linker 4-(3-hydroxybenzamido)butyl) phosphinic acid to ccugucgt modified_base 1 mod_base OTHER note thymine tcctgtccggagatgttgat 8 AA PAT SOURCE 1..8 ORGANISM Homo sapiens MOL_TYPE protein VARIANT 4 NOTE X can be any amino acid VARIANT 8 NOTE X can be any amino acid GGGXGGGX 400 AA PAT SOURCE 1..400 ORGANISM synthetic construct MOL_TYPE protein VARIANT 4..400 NOTE X can be any amino acid VARIANT 9..400 NOTE Up to 98 copies of GGGX can be deleted GGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGXGGGX 000 8 AA PAT SOURCE 1..8 ORGANISM Homo sapiens MOL_TYPE protein VARIANT 4 NOTE X can be any amino acid VARIANT 8 NOTE X can be any amino acid GGGXGGGX 12 AA PAT SOURCE 1..12 ORGANISM Homo sapiens MOL_TYPE protein VARIANT 4 NOTE X can be any amino acid VARIANT 8 NOTE X can be any amino acid VARIANT 12 NOTE X can be any amino acid GGGXGGGXGGGX 306 DNA PAT source 1..306 organism Homo sapiens mol_type genomic DNA CDS 19..114 translation MAPNTQTASPRALADSLMQLARQVSRLESGQ protein_id 47 CDS 115..222 translation MTMITDSLAVVLQRRDWENPGVTQLNRLAAHWCQK protein_id 48 CDS 251..283 translation MLRRQVNEVA protein_id 49 caattcagggtggtgaatatggcgcccaatacgcaaaccgcctctccccgcgcgttggccgattcattaatggaaagcgggcagtgaatgaccatgattacggattcactggccgtcgttttacaacgtcgtgactgggaaaaccctggcgttacccaacttaatcgccttgcagcacattggtgtcaaaaataataataaccggatgtactatttatccctgatgctgcgtcgtcaggtgaatgaagtcgcttaagcaatcaatgtcggatgcggcgcgacgcttatccgaccaacatatcataa 31 AA PAT SOURCE 1..31 ORGANISM Homo sapiens MOL_TYPE protein MAPNTQTASPRALADSLMQLARQVSRLESGQ 35 AA PAT SOURCE 1..35 ORGANISM Homo sapiens MOL_TYPE protein MTMITDSLAVVLQRRDWENPGVTQLNRLAAHWCQK 10 AA PAT SOURCE 1..10 ORGANISM Homo sapiens MOL_TYPE protein MLRRQVNEVA 10 AA PAT SOURCE 1..10 ORGANISM synthetic construct MOL_TYPE protein SITE 2 NOTE Homoserine VARIANT 3..6 NOTE A or G AXXXXXYLGS 17 AA PAT SOURCE 1..17 ORGANISM Homo sapiens MOL_TYPE protein DISULFID 4..15 CARBOHYD 9 NOTE Asn side-chain N-linked to asialyloligosaccharide LEYCLKRWNETISHCAW 106 AA PAT SOURCE 1..106 ORGANISM synthetic construct MOL_TYPE protein LLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKYMR 53 AA PAT SOURCE 1..53 ORGANISM synthetic construct MOL_TYPE protein VARIANT 2..3 NOTE X can be any amino acid VARIANT 5..24 NOTE X can be any amino acid VARIANT 26..28 NOTE X can be any amino acid VARIANT 30 NOTE deleted VARIANT 30..49 NOTE X can be any amino acid VARIANT 51..52 NOTE X can be any amino acid KXXKXXXXXXXXXXXXXXXXXXXXKXXXKXXXXXXXXXXXXXXXXXXXXKXXK 52 AA PAT SOURCE 1..52 ORGANISM synthetic construct MOL_TYPE protein VARIANT 2..3 NOTE X can be any amino acid VARIANT 5..24 NOTE X can be any amino acid VARIANT 26..28 NOTE X can be any amino acid VARIANT 29^30 NOTE X is inserted VARIANT 30..48 NOTE X can be any amino acid VARIANT 50..51 NOTE X can be any amino acid KXXKXXXXXXXXXXXXXXXXXXXXKXXXKXXXXXXXXXXXXXXXXXXXKXXK 63 AA PAT SOURCE 1..63 ORGANISM synthetic construct MOL_TYPE protein VARIANT 2..3 NOTE X can be any amino acid VARIANT 5..29 NOTE X can be any amino acid; up to 10 residues may be deleted VARIANT 31..33 NOTE X can be any amino acid VARIANT 35..59 NOTE X can be any amino acid; up to 10 residues may be deleted VARIANT 61..62 NOTE X can be any amino acid KXXKXXXXXXXXXXXXXXXXXXXXXXXXXKXXXKXXXXXXXXXXXXXXXXXXXXXXXXXKXXK 43 AA PAT SOURCE 1..43 ORGANISM synthetic construct MOL_TYPE protein VARIANT 2..3 NOTE X can be any amino acid VARIANT 5..19 NOTE X can be any amino acid; up to 10 X residues may be inserted VARIANT 21..23 NOTE X can be any amino acid VARIANT 25..39 NOTE X can be any amino acid; up to 10 X residues may be inserted VARIANT 41..42 NOTE X can be any amino acid KXXKXXXXXXXXXXXXXXXKXXXKXXXXXXXXXXXXXXXKXXK 6 AA PAT SOURCE 1..6 ORGANISM synthetic construct MOL_TYPE protein SITE 1 NOTE This residue is linked N-terminally to a peptide having an N-terminal Gly-Gly and a gap of undefined length VARIANT 5..6 NOTE X can be any amino acid GGAGXX 45 DNA PAT source 1..45 organism Homo sapiens mol_type genomic DNA CDS 1..45 translation MTGNKPETDVYEIL protein_id 59 atgaccggaaataaacctgaaaccgatgtttacgaaattttatga 14 AA PAT SOURCE 1..14 ORGANISM Homo sapiens MOL_TYPE protein MTGNKPETDVYEIL 22 DNA PAT source 1..22 organism Drosophila melanogaster mol_type genomic DNA acattgaatctcataccacttt 19 DNA PAT source 1..19 organism Drosophila virilis mol_type genomic DNA acatggatcccacgacttt 22 DNA PAT source 1..22 organism Drosophila simulans mol_type genomic DNA gtatggcgtcgtatsgtagttt 7 AA PAT SOURCE 1..7 ORGANISM Homo sapiens MOL_TYPE protein VARIANT 7 NOTE X is S or T GGGJATX 7 AA PAT SOURCE 1..7 ORGANISM Homo sapiens MOL_TYPE protein VARIANT 4 NOTE replace with I VARIANT 7 NOTE replace with T GGGLATS 7 AA PAT SOURCE 1..7 ORGANISM Homo sapiens MOL_TYPE protein VARIANT 4 NOTE X can be any amino acid GLPXRIC 7 AA PAT SOURCE 1..7 ORGANISM Homo sapiens MOL_TYPE protein GLPVRIC 7 AA PAT SOURCE 1..7 ORGANISM Homo sapiens MOL_TYPE protein GLPTRIC 7 AA PAT SOURCE 1..7 ORGANISM Homo sapiens MOL_TYPE protein GLPDRIC 36 DNA PAT source 1..36 organism Homo sapiens mol_type genomic DNA cgaatgncccactacgaatgncacgaatgncccaca 36 DNA PAT source 1..36 organism Homo sapiens mol_type genomic DNA cgaatgacccactacgaatgbcacgaatgbcccaca 36 DNA PAT source 1..36 organism Homo sapiens mol_type genomic DNA cgaatgtcccactacgaatgvcacgaatgvcccaca 36 DNA PAT source 1..36 organism Homo sapiens mol_type genomic DNA cgaatggcccactacgaatghcacgaatghcccaca 36 DNA PAT source 1..36 organism Homo sapiens mol_type genomic DNA cgaatgccccactacgaatgdcacgaatgdcccaca 400 DNA PAT source 1..400 organism Homo sapiens mol_type genomic DNA CDS join(1..79,142..212,272..400) protein_id 75 translation MKTFAALLSAVTLALSVRAQAAVWSQCGGTPGWTGETTCVAGSVCTSLSSSYSQCVPGSATSSAPAAPSATTSGPAPTDGTCSASGAWPPLT atgaagactttcgcagccttgctttccgctgtcactctcgcgctctcggtgcgcgcccaggcggctgtctggagtcaatgtaagtgccgctgcttttcattgatacgagactctacgccgagctgacgtgctaccgtataggtggcggtacaccgggttggacgggcgagaccacttgcgttgctggttcggtttgtacctccttgagctcagtgagcgactttcaatccgtcgtcattgctcctcatgtattgacgattggccttcatagtcatactctcaatgcgttccgggctccgcaacgtccagcgctccggcggccccctcagcgacaacttcaggccccgcacctacggacggaacgtgctcggccagcggggcatggccgccattgacctga 92 AA PAT SOURCE 1..92 ORGANISM Homo sapiens MOL_TYPE protein MKTFAALLSAVTLALSVRAQAAVWSQCGGTPGWTGETTCVAGSVCTSLSSSYSQCVPGSATSSAPAAPSATTSGPAPTDGTCSASGAWPPLT 9 AA PAT SOURCE 1..9 ORGANISM Homo sapiens MOL_TYPE protein AVLTYLRGE 9 AA PAT SOURCE 1..9 ORGANISM Homo sapiens MOL_TYPE protein AVLTYLRGA 9 AA PAT SOURCE 1..9 ORGANISM Homo sapiens MOL_TYPE protein AVPTYPRGE 9 AA PAT SOURCE 1..9 ORGANISM Homo sapiens MOL_TYPE protein AVAIGYRGE 8 AA PAT SOURCE 1..8 ORGANISM Homo sapiens MOL_TYPE protein AVLTYLGE 32 AA PAT SOURCE 1..32 ORGANISM synthetic construct MOL_TYPE protein VARIANT 4 NOTE N or T VARIANT 11 NOTE A or T VARIANT 12 NOTE K or Q VARIANT 18 NOTE K or Q or N or D VARIANT 21 NOTE R or G VARIANT 22 NOTE K or I or N VARIANT 24 NOTE L or V VARIANT 29 NOTE M or L LEGXEQFINAXXIIRHPXYBXXTXBNDIXLIK 32 AA PAT SOURCE 1..32 ORGANISM Homo sapiens MOL_TYPE protein LEGNEQFINAAKIIRHPQYDRKTLNNDIMLIK 32 AA PAT SOURCE 1..32 ORGANISM Pongo abelii MOL_TYPE protein LEGNEQFINAAKIIRHPQYDRKTVNNDIMLIK 32 AA PAT SOURCE 1..32 ORGANISM Papio anubis MOL_TYPE protein LEGTEQFINAAKIIRHPDYDRKTLNNDILLIK 32 AA PAT SOURCE 1..32 ORGANISM Rhinopithecus roxellana MOL_TYPE protein LEGTEQFINAAKIIRHPNYNRITLDNDILLIK 32 AA PAT SOURCE 1..32 ORGANISM Pan paniscus MOL_TYPE protein LEGNEQFINAAKIIRHPKYNRITLNNDIMLIK 32 AA PAT SOURCE 1..32 ORGANISM Rhinopithecus bieti MOL_TYPE protein LEGNEQFINATKIIRHPKYNGNTLNNDIMLIK 32 AA PAT SOURCE 1..32 ORGANISM Rhinopithecus roxellana MOL_TYPE protein LEGNEQFINATQIIRHPKYNGNTLNNDIMLIK 7 AA PAT SOURCE 1..7 ORGANISM synthetic construct MOL_TYPE protein SITE 1..7 NOTE Cysteine Leucine thioester (Cys-Leu) SITE 6 NOTE Lys side chain links the tripeptide ALE CALRDKL 5 AA PAT SOURCE 1..5 ORGANISM synthetic construct MOL_TYPE protein SITE 5 NOTE Ser is linked to another sequence through an amide linkage between Ser and a side chain of a Lys in the other sequence LRDQS 6 AA PAT SOURCE 1..6 ORGANISM synthetic construct MOL_TYPE protein REGION 1..6 NOTE Circular peptide SITE 4 NOTE The side chain of Lys is linked via an amide linkage to another sequence ALFKNG 43 DNA PAT source 1..43 organism synthetic construct mol_type other DNA misc_feature 1..7 note DNA fragment misc_feature 8..42 note RNA fragment misc_feature 43 note DNA fragment agaccttcggagtctcctgttgaacagatagtcaaagtagatc 216 DNA PAT source 1..216 organism Homo sapiens mol_type genomic DNA CDS <1..>216 protein_id 94 translation HHAAECGFCPQQWQVLRGSLCICEGPAEGWFISRCWLWCGPQVQGFIFGEGKEGGGDRRAEASPQEFWECTW catcacgcagcagaatgtggattttgtcctcaacaatggcaagttctacgtgggagtctgtgcatttgtgagggtccagctgaaggatggttcatatcaagatgttggttatggtgtgggcctcaagtccaaggctttatctttggagaaggcaaggaaggaggcggtgacagacgggctgaagcgagccctcaggagttttgggaatgcacttgg 72 AA PAT SOURCE 1..72 ORGANISM Homo sapiens MOL_TYPE protein HHAAECGFCPQQWQVLRGSLCICEGPAEGWFISRCWLWCGPQVQGFIFGEGKEGGGDRRAEASPQEFWECTW