227D. Where the sequence listing is transmitted online, the receiving Office encodes the international application number and type of sequence listing (as filed, corrected, for purpose of international search, etc.) in the filename, referencing XML or equivalent metadata appropriate to the means of online transmission. The content of the electronic file should not be changed.
227E. For any sequence listing received on a physical medium, the receiving Office may extract the file and transmit it online. In such a case, the receiving Office encodes the international application number and type of sequence listing in the filename or associated metadata in the same way as if the sequence listing had been received online. If the sequence listing is received on multiple data carriers, the receiving Office rejoins the extracted files to form one single contiguous file before transmitting it online.