                         SEQUENCE LISTING

<110>  DUKE UNIVERSITY
 
<120>  METHODS OF MANIPULATING CELL SIGNALING

<130>  028193-9064 WO00

<140>  New International Application
<141>  2010-07-08

<150>  61/223965
<151>  2009-07-08

<160>  20    

<170>  PatentIn version 3.5

<210>  1
<211>  7759
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  1
gacggatcgg gagatctccc gatcccctat ggtcgactct cagtacaatc tgctctgatg       60

ccgcatagtt aagccagtat ctgctccctg cttgtgtgtt ggaggtcgct gagtagtgcg      120

cgagcaaaat ttaagctaca acaaggcaag gcttgaccga caattgcatg aagaatctgc      180

ttagggttag gcgttttgcg ctgcttcgcg atgtacgggc cagatatacg cgttgacatt      240

gattattgac tagttattaa tagtaatcaa ttacggggtc attagttcat agcccatata      300

tggagttccg cgttacataa cttacggtaa atggcccgcc tggctgaccg cccaacgacc      360

cccgcccatt gacgtcaata atgacgtatg ttcccatagt aacgccaata gggactttcc      420

attgacgtca atgggtggac tatttacggt aaactgccca cttggcagta catcaagtgt      480

atcatatgcc aagtacgccc cctattgacg tcaatgacgg taaatggccc gcctggcatt      540

atgcccagta catgacctta tgggactttc ctacttggca gtacatctac gtattagtca      600

tcgctattac catggtgatg cggttttggc agtacatcaa tgggcgtgga tagcggtttg      660

actcacgggg atttccaagt ctccacccca ttgacgtcaa tgggagtttg ttttggcacc      720

aaaatcaacg ggactttcca aaatgtcgta acaactccgc cccattgacg caaatgggcg      780

gtaggcgtgt acggtgggag gtctatataa gcagagctct ctggctaact agagaaccca      840

ctgcttactg gcttatcgaa attaatacga ctcactatag ggagacccaa gctggctagt      900

taagcttgcc accatgggag tcaaagttct gtttgccctg atctgcatcg ctgtggccga      960

ggccaagccc accgagaaca acgaagactt caacatcgtg gccgtggcca gcaacttcgc     1020

gaccacggat ctcgatgctg accgcgggaa gttgcccggc aagaagctgc cgctggaggt     1080

gctcaaagag atggaagcca atgcccggaa agctggctgc accaggggct gtctgatctg     1140

cctgtcccac atcaagtgca cgcccaagat gaagaagttc atcccaggac gctgccacac     1200

ctacgaaggc gacaaagagt ccgcacaggg cggcataggc gaggcgatcg tcgacattcc     1260

tgagattcct gggttcaagg acttggagcc catggagcag ttcatcgcac aggtcgatct     1320

gtgtgtggac tgcacaactg gctgcctcaa agggcttgcc aacgtgcagt gttctgacct     1380

gctcaagaag tggctgccgc aacgctgtgc gacctttgcc agcaagatcc agggccaggt     1440

ggacaagatc aagggggccg gtggtgacgg ggatccacta gtccagtgtg gtggaattgc     1500

ccttgctgcc accatggact atggcggcgc tttgtctgcc gtcggacgcg aacttttgtt     1560

cgttactaat cctgtggtgg tgaacgggtc cgtcctggtc cctgaggatc aatgttactg     1620

tgccggatgg attgaatctc gcggcacgaa cggcgctcag accgcgtcaa atgtcctgca     1680

gtggcttgca gcaggattca gcattttgct gctgatgttc tatgcctacc aaacctggaa     1740

atctacatgc ggctgggagg agatctatgt gtgcgccatt gaaatggtta aggtgattct     1800

cgagttcttt tttgagttta agaatccctc tatgctctac cttgccacag gacaccgggt     1860

gcagtggctg cgctatgcag agtggctgct cacttgtcct gtcatcctta tccacctgag     1920

caacctcacc ggcctgagca acgactacag caggagaacc atgggactcc ttgtctcaga     1980

catcgggact atcgtgtggg gggctaccag cgccatggca accggctatg ttaaagtcat     2040

cttcttttgt cttggattgt gctatggcgc gaacacattt tttcacgccg ccaaagcata     2100

tatcgagggt tatcatactg tgccaaaggg tcggtgccgc caggtcgtga ccggcatggc     2160

atggctgttt ttcgtgagct ggggtatgtt cccaattctc ttcattttgg ggcccgaagg     2220

ttttggcgtc ctgagcgtct atggctccac cgtaggtcac acgattattg atctgatgag     2280

taaaaattgt tgggggttgt tgggacacta cctgcgcgtc ctgatccacg agcacatatt     2340

gattcacgga gatatccgca aaaccaccaa actgaacatc ggcggaacgg agatcgaggt     2400

cgagactctc gtcgaagacg aagccgaggc cggagccgtg ccagcggccg ccaccatggt     2460

gagcaagggc gaggagctgt tcaccggggt ggtgcccatc ctggtcgagc tggacggcga     2520

cgtaaacggc cacaagttca gcgtgtccgg cgagggcgag ggcgatgcca cctacggcaa     2580

gctgaccctg aagttcatct gcaccaccgg caagctgccc gtgccctggc ccaccctcgt     2640

gaccaccttc ggctacggcc tgcagtgctt cgcccgctac cccgaccaca tgaagcagca     2700

cgacttcttc aagtccgcca tgcccgaagg ctacgtccag gagcgcacca tcttcttcaa     2760

ggacgacggc aactacaaga cccgcgccga ggtgaagttc gagggcgaca ccctggtgaa     2820

ccgcatcgag ctgaagggca tcgacttcaa ggaggacggc aacatcctgg ggcacaagct     2880

ggagtacaac tacaacagcc acaacgtcta tatcatggcc gacaagcaga agaacggcat     2940

caaggtgaac ttcaagatcc gccacaacat cgaggacggc agcgtgcagc tcgccgacca     3000

ctaccagcag aacaccccca tcggcgacgg ccccgtgctg ctgcccgaca accactacct     3060

gagctaccag tccgccctga gcaaagaccc caacgagaag cgcgatcaca tggtcctgct     3120

ggagttcgtg accgccgccg ggatcactct cggcatggac gagctgtaca agtaacatat     3180

gctctctcta agggcaattc tgcagatatc cagcacagtg gcggccgctc gagtctagag     3240

ggcccgcggt tcgaaggtaa gcctatccct aaccctctcc tcggtctcga ttctacgcgt     3300

accggtcatc atcaccatca ccattgagtt taaacccgct gatcagcctc gactgtgcct     3360

tctagttgcc agccatctgt tgtttgcccc tcccccgtgc cttccttgac cctggaaggt     3420

gccactccca ctgtcctttc ctaataaaat gaggaaattg catcgcattg tctgagtagg     3480

tgtcattcta ttctgggggg tggggtgggg caggacagca agggggagga ttgggaagac     3540

aatagcaggc atgctgggga tgcggtgggc tctatggctt ctgaggcgga aagaaccagc     3600

tggggctcta gggggtatcc ccacgcgccc tgtagcggcg cattaagcgc ggcgggtgtg     3660

gtggttacgc gcagcgtgac cgctacactt gccagcgccc tagcgcccgc tcctttcgct     3720

ttcttccctt cctttctcgc cacgttcgcc ggctttcccc gtcaagctct aaatcggggc     3780

atccctttag ggttccgatt tagtgcttta cggcacctcg accccaaaaa acttgattag     3840

ggtgatggtt cacgtagtgg gccatcgccc tgatagacgg tttttcgccc tttgacgttg     3900

gagtccacgt tctttaatag tggactcttg ttccaaactg gaacaacact caaccctatc     3960

tcggtctatt cttttgattt ataagggatt ttggggattt cggcctattg gttaaaaaat     4020

gagctgattt aacaaaaatt taacgcgaat taattctgtg gaatgtgtgt cagttagggt     4080

gtggaaagtc cccaggctcc ccaggcaggc agaagtatgc aaagcatgca tctcaattag     4140

tcagcaacca ggtgtggaaa gtccccaggc tccccagcag gcagaagtat gcaaagcatg     4200

catctcaatt agtcagcaac catagtcccg cccctaactc cgcccatccc gcccctaact     4260

ccgcccagtt ccgcccattc tccgccccat ggctgactaa ttttttttat ttatgcagag     4320

gccgaggccg cctctgcctc tgagctattc cagaagtagt gaggaggctt ttttggaggc     4380

ctaggctttt gcaaaaagct cccgggagct tgtatatcca ttttcggatc tgatcaagag     4440

acaggatgag gatcgtttcg catgattgaa caagatggat tgcacgcagg ttctccggcc     4500

gcttgggtgg agaggctatt cggctatgac tgggcacaac agacaatcgg ctgctctgat     4560

gccgccgtgt tccggctgtc agcgcagggg cgcccggttc tttttgtcaa gaccgacctg     4620

tccggtgccc tgaatgaact gcaggacgag gcagcgcggc tatcgtggct ggccacgacg     4680

ggcgttcctt gcgcagctgt gctcgacgtt gtcactgaag cgggaaggga ctggctgcta     4740

ttgggcgaag tgccggggca ggatctcctg tcatctcacc ttgctcctgc cgagaaagta     4800

tccatcatgg ctgatgcaat gcggcggctg catacgcttg atccggctac ctgcccattc     4860

gaccaccaag cgaaacatcg catcgagcga gcacgtactc ggatggaagc cggtcttgtc     4920

gatcaggatg atctggacga agagcatcag gggctcgcgc cagccgaact gttcgccagg     4980

ctcaaggcgc gcatgcccga cggcgaggat ctcgtcgtga cccatggcga tgcctgcttg     5040

ccgaatatca tggtggaaaa tggccgcttt tctggattca tcgactgtgg ccggctgggt     5100

gtggcggacc gctatcagga catagcgttg gctacccgtg atattgctga agagcttggc     5160

ggcgaatggg ctgaccgctt cctcgtgctt tacggtatcg ccgctcccga ttcgcagcgc     5220

atcgccttct atcgccttct tgacgagttc ttctgagcgg gactctgggg ttcgcgaaat     5280

gaccgaccaa gcgacgccca acctgccatc acgagatttc gattccaccg ccgccttcta     5340

tgaaaggttg ggcttcggaa tcgttttccg ggacgccggc tggatgatcc tccagcgcgg     5400

ggatctcatg ctggagttct tcgcccaccc caacttgttt attgcagctt ataatggtta     5460

caaataaagc aatagcatca caaatttcac aaataaagca tttttttcac tgcattctag     5520

ttgtggtttg tccaaactca tcaatgtatc ttatcatgtc tgtataccgt cgacctctag     5580

ctagagcttg gcgtaatcat ggtcatagct gtttcctgtg tgaaattgtt atccgctcac     5640

aattccacac aacatacgag ccggaagcat aaagtgtaaa gcctggggtg cctaatgagt     5700

gagctaactc acattaattg cgttgcgctc actgcccgct ttccagtcgg gaaacctgtc     5760

gtgccagctg cattaatgaa tcggccaacg cgcggggaga ggcggtttgc gtattgggcg     5820

ctcttccgct tcctcgctca ctgactcgct gcgctcggtc gttcggctgc ggcgagcggt     5880

atcagctcac tcaaaggcgg taatacggtt atccacagaa tcaggggata acgcaggaaa     5940

gaacatgtga gcaaaaggcc agcaaaaggc caggaaccgt aaaaaggccg cgttgctggc     6000

gtttttccat aggctccgcc cccctgacga gcatcacaaa aatcgacgct caagtcagag     6060

gtggcgaaac ccgacaggac tataaagata ccaggcgttt ccccctggaa gctccctcgt     6120

gcgctctcct gttccgaccc tgccgcttac cggatacctg tccgcctttc tcccttcggg     6180

aagcgtggcg ctttctcaat gctcacgctg taggtatctc agttcggtgt aggtcgttcg     6240

ctccaagctg ggctgtgtgc acgaaccccc cgttcagccc gaccgctgcg ccttatccgg     6300

taactatcgt cttgagtcca acccggtaag acacgactta tcgccactgg cagcagccac     6360

tggtaacagg attagcagag cgaggtatgt aggcggtgct acagagttct tgaagtggtg     6420

gcctaactac ggctacacta gaaggacagt atttggtatc tgcgctctgc tgaagccagt     6480

taccttcgga aaaagagttg gtagctcttg atccggcaaa caaaccaccg ctggtagcgg     6540

tggttttttt gtttgcaagc agcagattac gcgcagaaaa aaaggatctc aagaagatcc     6600

tttgatcttt tctacggggt ctgacgctca gtggaacgaa aactcacgtt aagggatttt     6660

ggtcatgaga ttatcaaaaa ggatcttcac ctagatcctt ttaaattaaa aatgaagttt     6720

taaatcaatc taaagtatat atgagtaaac ttggtctgac agttaccaat gcttaatcag     6780

tgaggcacct atctcagcga tctgtctatt tcgttcatcc atagttgcct gactccccgt     6840

cgtgtagata actacgatac gggagggctt accatctggc cccagtgctg caatgatacc     6900

gcgagaccca cgctcaccgg ctccagattt atcagcaata aaccagccag ccggaagggc     6960

cgagcgcaga agtggtcctg caactttatc cgcctccatc cagtctatta attgttgccg     7020

ggaagctaga gtaagtagtt cgccagttaa tagtttgcgc aacgttgttg ccattgctac     7080

aggcatcgtg gtgtcacgct cgtcgtttgg tatggcttca ttcagctccg gttcccaacg     7140

atcaaggcga gttacatgat cccccatgtt gtgcaaaaaa gcggttagct ccttcggtcc     7200

tccgatcgtt gtcagaagta agttggccgc agtgttatca ctcatggtta tggcagcact     7260

gcataattct cttactgtca tgccatccgt aagatgcttt tctgtgactg gtgagtactc     7320

aaccaagtca ttctgagaat agtgtatgcg gcgaccgagt tgctcttgcc cggcgtcaat     7380

acgggataat accgcgccac atagcagaac tttaaaagtg ctcatcattg gaaaacgttc     7440

ttcggggcga aaactctcaa ggatcttacc gctgttgaga tccagttcga tgtaacccac     7500

tcgtgcaccc aactgatctt cagcatcttt tactttcacc agcgtttctg ggtgagcaaa     7560

aacaggaagg caaaatgccg caaaaaaggg aataagggcg acacggaaat gttgaatact     7620

catactcttc ctttttcaat attattgaag catttatcag ggttattgtc tcatgagcgg     7680

atacatattt gaatgtattt agaaaaataa acaaataggg gttccgcgca catttccccg     7740

aaaagtgcca cctgacgtc                                                  7759


<210>  2
<211>  7208
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  2
gacggatcgg gagatctccc gatcccctat ggtcgactct cagtacaatc tgctctgatg       60

ccgcatagtt aagccagtat ctgctccctg cttgtgtgtt ggaggtcgct gagtagtgcg      120

cgagcaaaat ttaagctaca acaaggcaag gcttgaccga caattgcatg aagaatctgc      180

ttagggttag gcgttttgcg ctgcttcgcg atgtacgggc cagatatacg cgttgacatt      240

gattattgac tagttattaa tagtaatcaa ttacggggtc attagttcat agcccatata      300

tggagttccg cgttacataa cttacggtaa atggcccgcc tggctgaccg cccaacgacc      360

cccgcccatt gacgtcaata atgacgtatg ttcccatagt aacgccaata gggactttcc      420

attgacgtca atgggtggac tatttacggt aaactgccca cttggcagta catcaagtgt      480

atcatatgcc aagtacgccc cctattgacg tcaatgacgg taaatggccc gcctggcatt      540

atgcccagta catgacctta tgggactttc ctacttggca gtacatctac gtattagtca      600

tcgctattac catggtgatg cggttttggc agtacatcaa tgggcgtgga tagcggtttg      660

actcacgggg atttccaagt ctccacccca ttgacgtcaa tgggagtttg ttttggcacc      720

aaaatcaacg ggactttcca aaatgtcgta acaactccgc cccattgacg caaatgggcg      780

gtaggcgtgt acggtgggag gtctatataa gcagagctct ctggctaact agagaaccca      840

ctgcttactg gcttatcgaa attaatacga ctcactatag ggagacccaa gctggctagt      900

taagcttggt accgagctcg gatccactag tccagtgtgg tggaattgcc cttgctgcca      960

ccatggacta tggcggcgct ttgtctgccg tcggacgcga acttttgttc gttactaatc     1020

ctgtggtggt gaacgggtcc gtcctggtcc ctgaggatca atgttactgt gccggatgga     1080

ttgaatctcg cggcacgaac ggcgctcaga ccgcgtcaaa tgtcctgcag tggcttgcag     1140

caggattcag cattttgctg ctgatgttct atgcctacca aacctggaaa tctacatgcg     1200

gctgggagga gatctatgtg tgcgccattg aaatggttaa ggtgattctc gagttctttt     1260

ttgagtttaa gaatccctct atgctctacc ttgccacagg acaccgggtg cagtggctgc     1320

gctatgcaga gtggctgctc acttgtcctg tcatccttat ccacctgagc aacctcaccg     1380

gcctgagcaa cgactacagc aggagaacca tgggactcct tgtctcagac atcgggacta     1440

tcgtgtgggg ggctaccagc gccatggcaa ccggctatgt taaagtcatc ttcttttgtc     1500

ttggattgtg ctatggcgcg aacacatttt ttcacgccgc caaagcatat atcgagggtt     1560

atcatactgt gccaaagggt cggtgccgcc aggtcgtgac cggcatggca tggctgtttt     1620

tcgtgagctg gggtatgttc ccaattctct tcattttggg gcccgaaggt tttggcgtcc     1680

tgagcgtcta tggctccacc gtaggtcaca cgattattga tctgatgagt aaaaattgtt     1740

gggggttgtt gggacactac ctgcgcgtcc tgatccacga gcacatattg attcacggag     1800

atatccgcaa aaccaccaaa ctgaacatcg gcggaacgga gatcgaggtc gagactctcg     1860

tcgaagacga agccgaggcc ggagccgtgc cagcggccgc caccatggtg agcaagggcg     1920

aggagctgtt caccggggtg gtgcccatcc tggtcgagct ggacggcgac gtaaacggcc     1980

acaagttcag cgtgtccggc gagggcgagg gcgatgccac ctacggcaag ctgaccctga     2040

agttcatctg caccaccggc aagctgcccg tgccctggcc caccctcgtg accaccttcg     2100

gctacggcct gcagtgcttc gcccgctacc ccgaccacat gaagcagcac gacttcttca     2160

agtccgccat gcccgaaggc tacgtccagg agcgcaccat cttcttcaag gacgacggca     2220

actacaagac ccgcgccgag gtgaagttcg agggcgacac cctggtgaac cgcatcgagc     2280

tgaagggcat cgacttcaag gaggacggca acatcctggg gcacaagctg gagtacaact     2340

acaacagcca caacgtctat atcatggccg acaagcagaa gaacggcatc aaggtgaact     2400

tcaagatccg ccacaacatc gaggacggca gcgtgcagct cgccgaccac taccagcaga     2460

acacccccat cggcgacggc cccgtgctgc tgcccgacaa ccactacctg agctaccagt     2520

ccgccctgag caaagacccc aacgagaagc gcgatcacat ggtcctgctg gagttcgtga     2580

ccgccgccgg gatcactctc ggcatggacg agctgtacaa gtaacatatg ctctctctaa     2640

gggcaattct gcagatatcc agcacagtgg cggccgctcg agtctagagg gcccgcggtt     2700

cgaaggtaag cctatcccta accctctcct cggtctcgat tctacgcgta ccggtcatca     2760

tcaccatcac cattgagttt aaacccgctg atcagcctcg actgtgcctt ctagttgcca     2820

gccatctgtt gtttgcccct cccccgtgcc ttccttgacc ctggaaggtg ccactcccac     2880

tgtcctttcc taataaaatg aggaaattgc atcgcattgt ctgagtaggt gtcattctat     2940

tctggggggt ggggtggggc aggacagcaa gggggaggat tgggaagaca atagcaggca     3000

tgctggggat gcggtgggct ctatggcttc tgaggcggaa agaaccagct ggggctctag     3060

ggggtatccc cacgcgccct gtagcggcgc attaagcgcg gcgggtgtgg tggttacgcg     3120

cagcgtgacc gctacacttg ccagcgccct agcgcccgct cctttcgctt tcttcccttc     3180

ctttctcgcc acgttcgccg gctttccccg tcaagctcta aatcggggca tccctttagg     3240

gttccgattt agtgctttac ggcacctcga ccccaaaaaa cttgattagg gtgatggttc     3300

acgtagtggg ccatcgccct gatagacggt ttttcgccct ttgacgttgg agtccacgtt     3360

ctttaatagt ggactcttgt tccaaactgg aacaacactc aaccctatct cggtctattc     3420

ttttgattta taagggattt tggggatttc ggcctattgg ttaaaaaatg agctgattta     3480

acaaaaattt aacgcgaatt aattctgtgg aatgtgtgtc agttagggtg tggaaagtcc     3540

ccaggctccc caggcaggca gaagtatgca aagcatgcat ctcaattagt cagcaaccag     3600

gtgtggaaag tccccaggct ccccagcagg cagaagtatg caaagcatgc atctcaatta     3660

gtcagcaacc atagtcccgc ccctaactcc gcccatcccg cccctaactc cgcccagttc     3720

cgcccattct ccgccccatg gctgactaat tttttttatt tatgcagagg ccgaggccgc     3780

ctctgcctct gagctattcc agaagtagtg aggaggcttt tttggaggcc taggcttttg     3840

caaaaagctc ccgggagctt gtatatccat tttcggatct gatcaagaga caggatgagg     3900

atcgtttcgc atgattgaac aagatggatt gcacgcaggt tctccggccg cttgggtgga     3960

gaggctattc ggctatgact gggcacaaca gacaatcggc tgctctgatg ccgccgtgtt     4020

ccggctgtca gcgcaggggc gcccggttct ttttgtcaag accgacctgt ccggtgccct     4080

gaatgaactg caggacgagg cagcgcggct atcgtggctg gccacgacgg gcgttccttg     4140

cgcagctgtg ctcgacgttg tcactgaagc gggaagggac tggctgctat tgggcgaagt     4200

gccggggcag gatctcctgt catctcacct tgctcctgcc gagaaagtat ccatcatggc     4260

tgatgcaatg cggcggctgc atacgcttga tccggctacc tgcccattcg accaccaagc     4320

gaaacatcgc atcgagcgag cacgtactcg gatggaagcc ggtcttgtcg atcaggatga     4380

tctggacgaa gagcatcagg ggctcgcgcc agccgaactg ttcgccaggc tcaaggcgcg     4440

catgcccgac ggcgaggatc tcgtcgtgac ccatggcgat gcctgcttgc cgaatatcat     4500

ggtggaaaat ggccgctttt ctggattcat cgactgtggc cggctgggtg tggcggaccg     4560

ctatcaggac atagcgttgg ctacccgtga tattgctgaa gagcttggcg gcgaatgggc     4620

tgaccgcttc ctcgtgcttt acggtatcgc cgctcccgat tcgcagcgca tcgccttcta     4680

tcgccttctt gacgagttct tctgagcggg actctggggt tcgcgaaatg accgaccaag     4740

cgacgcccaa cctgccatca cgagatttcg attccaccgc cgccttctat gaaaggttgg     4800

gcttcggaat cgttttccgg gacgccggct ggatgatcct ccagcgcggg gatctcatgc     4860

tggagttctt cgcccacccc aacttgttta ttgcagctta taatggttac aaataaagca     4920

atagcatcac aaatttcaca aataaagcat ttttttcact gcattctagt tgtggtttgt     4980

ccaaactcat caatgtatct tatcatgtct gtataccgtc gacctctagc tagagcttgg     5040

cgtaatcatg gtcatagctg tttcctgtgt gaaattgtta tccgctcaca attccacaca     5100

acatacgagc cggaagcata aagtgtaaag cctggggtgc ctaatgagtg agctaactca     5160

cattaattgc gttgcgctca ctgcccgctt tccagtcggg aaacctgtcg tgccagctgc     5220

attaatgaat cggccaacgc gcggggagag gcggtttgcg tattgggcgc tcttccgctt     5280

cctcgctcac tgactcgctg cgctcggtcg ttcggctgcg gcgagcggta tcagctcact     5340

caaaggcggt aatacggtta tccacagaat caggggataa cgcaggaaag aacatgtgag     5400

caaaaggcca gcaaaaggcc aggaaccgta aaaaggccgc gttgctggcg tttttccata     5460

ggctccgccc ccctgacgag catcacaaaa atcgacgctc aagtcagagg tggcgaaacc     5520

cgacaggact ataaagatac caggcgtttc cccctggaag ctccctcgtg cgctctcctg     5580

ttccgaccct gccgcttacc ggatacctgt ccgcctttct cccttcggga agcgtggcgc     5640

tttctcaatg ctcacgctgt aggtatctca gttcggtgta ggtcgttcgc tccaagctgg     5700

gctgtgtgca cgaacccccc gttcagcccg accgctgcgc cttatccggt aactatcgtc     5760

ttgagtccaa cccggtaaga cacgacttat cgccactggc agcagccact ggtaacagga     5820

ttagcagagc gaggtatgta ggcggtgcta cagagttctt gaagtggtgg cctaactacg     5880

gctacactag aaggacagta tttggtatct gcgctctgct gaagccagtt accttcggaa     5940

aaagagttgg tagctcttga tccggcaaac aaaccaccgc tggtagcggt ggtttttttg     6000

tttgcaagca gcagattacg cgcagaaaaa aaggatctca agaagatcct ttgatctttt     6060

ctacggggtc tgacgctcag tggaacgaaa actcacgtta agggattttg gtcatgagat     6120

tatcaaaaag gatcttcacc tagatccttt taaattaaaa atgaagtttt aaatcaatct     6180

aaagtatata tgagtaaact tggtctgaca gttaccaatg cttaatcagt gaggcaccta     6240

tctcagcgat ctgtctattt cgttcatcca tagttgcctg actccccgtc gtgtagataa     6300

ctacgatacg ggagggctta ccatctggcc ccagtgctgc aatgataccg cgagacccac     6360

gctcaccggc tccagattta tcagcaataa accagccagc cggaagggcc gagcgcagaa     6420

gtggtcctgc aactttatcc gcctccatcc agtctattaa ttgttgccgg gaagctagag     6480

taagtagttc gccagttaat agtttgcgca acgttgttgc cattgctaca ggcatcgtgg     6540

tgtcacgctc gtcgtttggt atggcttcat tcagctccgg ttcccaacga tcaaggcgag     6600

ttacatgatc ccccatgttg tgcaaaaaag cggttagctc cttcggtcct ccgatcgttg     6660

tcagaagtaa gttggccgca gtgttatcac tcatggttat ggcagcactg cataattctc     6720

ttactgtcat gccatccgta agatgctttt ctgtgactgg tgagtactca accaagtcat     6780

tctgagaata gtgtatgcgg cgaccgagtt gctcttgccc ggcgtcaata cgggataata     6840

ccgcgccaca tagcagaact ttaaaagtgc tcatcattgg aaaacgttct tcggggcgaa     6900

aactctcaag gatcttaccg ctgttgagat ccagttcgat gtaacccact cgtgcaccca     6960

actgatcttc agcatctttt actttcacca gcgtttctgg gtgagcaaaa acaggaaggc     7020

aaaatgccgc aaaaaaggga ataagggcga cacggaaatg ttgaatactc atactcttcc     7080

tttttcaata ttattgaagc atttatcagg gttattgtct catgagcgga tacatatttg     7140

aatgtattta gaaaaataaa caaatagggg ttccgcgcac atttccccga aaagtgccac     7200

ctgacgtc                                                              7208


<210>  3
<211>  5764
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  3
gacggatcgg gagatctccc gatcccctat ggtcgactct cagtacaatc tgctctgatg       60

ccgcatagtt aagccagtat ctgctccctg cttgtgtgtt ggaggtcgct gagtagtgcg      120

cgagcaaaat ttaagctaca acaaggcaag gcttgaccga caattgcatg aagaatctgc      180

ttagggttag gcgttttgcg ctgcttcgcg atgtacgggc cagatatacg cgttgacatt      240

gattattgac tagttattaa tagtaatcaa ttacggggtc attagttcat agcccatata      300

tggagttccg cgttacataa cttacggtaa atggcccgcc tggctgaccg cccaacgacc      360

cccgcccatt gacgtcaata atgacgtatg ttcccatagt aacgccaata gggactttcc      420

attgacgtca atgggtggac tatttacggt aaactgccca cttggcagta catcaagtgt      480

atcatatgcc aagtacgccc cctattgacg tcaatgacgg taaatggccc gcctggcatt      540

atgcccagta catgacctta tgggactttc ctacttggca gtacatctac gtattagtca      600

tcgctattac catggtgatg cggttttggc agtacatcaa tgggcgtgga tagcggtttg      660

actcacgggg atttccaagt ctccacccca ttgacgtcaa tgggagtttg ttttggcacc      720

aaaatcaacg ggactttcca aaatgtcgta acaactccgc cccattgacg caaatgggcg      780

gtaggcgtgt acggtgggag gtctatataa gcagagctct ctggctaact agagaaccca      840

ctgcttactg gcttatcgaa attaatacga ctcactatag ggagacccaa gcttggtacc      900

gagctcggat ccagccacca tgggagtcaa agttctgttt gccctgatct gcatcgctgt      960

ggccgaggcc aagcccaccg agaacaacga agacttcaac atcgtggccg tggccagcaa     1020

cttcgcgacc acggatctcg atgctgaccg cgggaagttg cccggcaaga agctgccgct     1080

ggaggtgctc aaagagatgg aagccaatgc ccggaaagct ggctgcacca ggggctgtct     1140

gatctgcctg tcccacatca agtgcacgcc caagatgaag aagttcatcc caggacgctg     1200

ccacacctac gaaggcgaca aagagtccgc acagggcggc ataggcgagg cgatcgtcga     1260

cattcctgag attcctgggt tcaaggactt ggagcccatg gagcagttca tcgcacaggt     1320

cgatctgtgt gtggactgca caactggctg cctcaaaggg cttgccaacg tgcagtgttc     1380

tgacctgctc aagaagtggc tgccgcaacg ctgtgcgacc tttgccagca agatccaggg     1440

ccaggtggac aagatcaagg gggccggtgg tgactaagcg gccgctcgag catgcatcta     1500

gaaataattc ttactgtcat gccaagtaag atgcttttct gtgctgcaat agcaggcatg     1560

ctggggatgc ggtgggctct atggcttctg aggcggaaag aaccagctgg ggctctaggg     1620

ggtatcccca cgcgccctgt agcggcgcat taagcgcggc gggtgtggtg gttacgcgca     1680

gcgtgaccgc tacacttgcc agcgccctag cgcccgctcc tttcgctttc ttcccttcct     1740

ttctcgccac gttcgccggc tttccccgtc aagctctaaa tcggggcatc cctttagggt     1800

tccgatttag tgctttacgg cacctcgacc ccaaaaaact tgattagggt gatggttcac     1860

gtagtgggcc atcgccctga tagacggttt ttcgcccttt gacgttggag tccacgttct     1920

ttaatagtgg actcttgttc caaactggaa caacactcaa ccctatctcg gtctattctt     1980

ttgatttata agggattttg gggatttcgg cctattggtt aaaaaatgag ctgatttaac     2040

aaaaatttaa cgcgaattaa ttctgtggaa tgtgtgtcag ttagggtgtg gaaagtcccc     2100

aggctcccca ggcaggcaga agtatgcaaa gcatgcatct caattagtca gcaaccaggt     2160

gtggaaagtc cccaggctcc ccagcaggca gaagtatgca aagcatgcat ctcaattagt     2220

cagcaaccat agtcccgccc ctaactccgc ccatcccgcc cctaactccg cccagttccg     2280

cccattctcc gccccatggc tgactaattt tttttattta tgcagaggcc gaggccgcct     2340

ctgcctctga gctattccag aagtagtgag gaggcttttt tggaggccta ggcttttgca     2400

aaaagctccc gggagcttgt atatccattt tcggatctga tcaagagaca ggatgaggat     2460

cgtttcgcat gattgaacaa gatggattgc acgcaggttc tccggccgct tgggtggaga     2520

ggctattcgg ctatgactgg gcacaacaga caatcggctg ctctgatgcc gccgtgttcc     2580

ggctgtcagc gcaggggcgc ccggttcttt ttgtcaagac cgacctgtcc ggtgccctga     2640

atgaactgca ggacgaggca gcgcggctat cgtggctggc cacgacgggc gttccttgcg     2700

cagctgtgct cgacgttgtc actgaagcgg gaagggactg gctgctattg ggcgaagtgc     2760

cggggcagga tctcctgtca tctcaccttg ctcctgccga gaaagtatcc atcatggctg     2820

atgcaatgcg gcggctgcat acgcttgatc cggctacctg cccattcgac caccaagcga     2880

aacatcgcat cgagcgagca cgtactcgga tggaagccgg tcttgtcgat caggatgatc     2940

tggacgaaga gcatcagggg ctcgcgccag ccgaactgtt cgccaggctc aaggcgcgca     3000

tgcccgacgg cgaggatctc gtcgtgaccc atggcgatgc ctgcttgccg aatatcatgg     3060

tggaaaatgg ccgcttttct ggattcatcg actgtggccg gctgggtgtg gcggaccgct     3120

atcaggacat agcgttggct acccgtgata ttgctgaaga gcttggcggc gaatgggctg     3180

accgcttcct cgtgctttac ggtatcgccg ctcccgattc gcagcgcatc gccttctatc     3240

gccttcttga cgagttcttc tgagcgggac tctggggttc gaaatgaccg accaagcgac     3300

gcccaacctg ccatcacgag atttcgattc caccgccgcc ttctatgaaa ggttgggctt     3360

cggaatcgtt ttccgggacg ccggctggat gatcctccag cgcggggatc tcatgctgga     3420

gttcttcgcc caccccaact tgtttattgc agcttataat ggttacaaat aaagcaatag     3480

catcacaaat ttcacaaata aagcattttt ttcactgcat tctagttgtg gtttgtccaa     3540

actcatcaat gtatcttatc atgtctgtat accgtcgacc tctagctaga gcttggcgta     3600

atcatggtca tagctgtttc ctgtgtgaaa ttgttatccg ctcacaattc cacacaacat     3660

acgagccgga agcataaagt gtaaagcctg gggtgcctaa tgagtgagct aactcacatt     3720

aattgcgttg cgctcactgc ccgctttcca gtcgggaaac ctgtcgtgcc agctgcatta     3780

atgaatcggc caacgcgcgg ggagaggcgg tttgcgtatt gggcgctctt ccgcttcctc     3840

gctcactgac tcgctgcgct cggtcgttcg gctgcggcga gcggtatcag ctcactcaaa     3900

ggcggtaata cggttatcca cagaatcagg ggataacgca ggaaagaaca tgtgagcaaa     3960

aggccagcaa aaggccagga accgtaaaaa ggccgcgttg ctggcgtttt tccataggct     4020

ccgcccccct gacgagcatc acaaaaatcg acgctcaagt cagaggtggc gaaacccgac     4080

aggactataa agataccagg cgtttccccc tggaagctcc ctcgtgcgct ctcctgttcc     4140

gaccctgccg cttaccggat acctgtccgc ctttctccct tcgggaagcg tggcgctttc     4200

tcaatgctca cgctgtaggt atctcagttc ggtgtaggtc gttcgctcca agctgggctg     4260

tgtgcacgaa ccccccgttc agcccgaccg ctgcgcctta tccggtaact atcgtcttga     4320

gtccaacccg gtaagacacg acttatcgcc actggcagca gccactggta acaggattag     4380

cagagcgagg tatgtaggcg gtgctacaga gttcttgaag tggtggccta actacggcta     4440

cactagaagg acagtatttg gtatctgcgc tctgctgaag ccagttacct tcggaaaaag     4500

agttggtagc tcttgatccg gcaaacaaac caccgctggt agcggtggtt tttttgtttg     4560

caagcagcag attacgcgca gaaaaaaagg atctcaagaa gatcctttga tcttttctac     4620

ggggtctgac gctcagtgga acgaaaactc acgttaaggg attttggtca tgagattatc     4680

aaaaaggatc ttcacctaga tccttttaaa ttaaaaatga agttttaaat caatctaaag     4740

tatatatgag taaacttggt ctgacagtta ccaatgctta atcagtgagg cacctatctc     4800

agcgatctgt ctatttcgtt catccatagt tgcctgactc cccgtcgtgt agataactac     4860

gatacgggag ggcttaccat ctggccccag tgctgcaatg ataccgcgag acccacgctc     4920

accggctcca gatttatcag caataaacca gccagccgga agggccgagc gcagaagtgg     4980

tcctgcaact ttatccgcct ccatccagtc tattaattgt tgccgggaag ctagagtaag     5040

tagttcgcca gttaatagtt tgcgcaacgt tgttgccatt gctacaggca tcgtggtgtc     5100

acgctcgtcg tttggtatgg cttcattcag ctccggttcc caacgatcaa ggcgagttac     5160

atgatccccc atgttgtgca aaaaagcggt tagctccttc ggtcctccga tcgttgtcag     5220

aagtaagttg gccgcagtgt tatcactcat ggttatggca gcactgcata attctcttac     5280

tgtcatgcca tccgtaagat gcttttctgt gactggtgag tactcaacca agtcattctg     5340

agaatagtgt atgcggcgac cgagttgctc ttgcccggcg tcaatacggg ataataccgc     5400

gccacatagc agaactttaa aagtgctcat cattggaaaa cgttcttcgg ggcgaaaact     5460

ctcaaggatc ttaccgctgt tgagatccag ttcgatgtaa cccactcgtg cacccaactg     5520

atcttcagca tcttttactt tcaccagcgt ttctgggtga gcaaaaacag gaaggcaaaa     5580

tgccgcaaaa aagggaataa gggcgacacg gaaatgttga atactcatac tcttcctttt     5640

tcaatattat tgaagcattt atcagggtta ttgtctcatg agcggataca tatttgaatg     5700

tatttagaaa aataaacaaa taggggttcc gcgcacattt ccccgaaaag tgccacctga     5760

cgtc                                                                  5764


<210>  4
<211>  10693
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  4
gtcgacggat cgggagatct cccgatcccc tatggtgcac tctcagtaca atctgctctg       60

atgccgcata gttaagccag tatctgctcc ctgcttgtgt gttggaggtc gctgagtagt      120

gcgcgagcaa aatttaagct acaacaaggc aaggcttgac cgacaattgc atgaagaatc      180

tgcttagggt taggcgtttt gcgctgcttc gcgatgtacg ggccagatat acgcgttgac      240

attgattatt gactagttat taatagtaat caattacggg gtcattagtt catagcccat      300

atatggagtt ccgcgttaca taacttacgg taaatggccc gcctggctga ccgcccaacg      360

acccccgccc attgacgtca ataatgacgt atgttcccat agtaacgcca atagggactt      420

tccattgacg tcaatgggtg gagtatttac ggtaaactgc ccacttggca gtacatcaag      480

tgtatcatat gccaagtacg ccccctattg acgtcaatga cggtaaatgg cccgcctggc      540

attatgccca gtacatgacc ttatgggact ttcctacttg gcagtacatc tacgtattag      600

tcatcgctat taccatggtg atgcggtttt ggcagtacat caatgggcgt ggatagcggt      660

ttgactcacg gggatttcca agtctccacc ccattgacgt caatgggagt ttgttttggc      720

accaaaatca acgggacttt ccaaaatgtc gtaacaactc cgccccattg acgcaaatgg      780

gcggtaggcg tgtacggtgg gaggtctata taagcagcgc gttttgcctg tactgggtct      840

ctctggttag accagatctg agcctgggag ctctctggct aactagggaa cccactgctt      900

aagcctcaat aaagcttgcc ttgagtgctt caagtagtgt gtgcccgtct gttgtgtgac      960

tctggtaact agagatccct cagacccttt tagtcagtgt ggaaaatctc tagcagtggc     1020

gcccgaacag ggacttgaaa gcgaaaggga aaccagagga gctctctcga cgcaggactc     1080

ggcttgctga agcgcgcacg gcaagaggcg aggggcggcg actggtgagt acgccaaaaa     1140

ttttgactag cggaggctag aaggagagag atgggtgcga gagcgtcagt attaagcggg     1200

ggagaattag atcgcgatgg gaaaaaattc ggttaaggcc agggggaaag aaaaaatata     1260

aattaaaaca tatagtatgg gcaagcaggg agctagaacg attcgcagtt aatcctggcc     1320

tgttagaaac atcagaaggc tgtagacaaa tactgggaca gctacaacca tcccttcaga     1380

caggatcaga agaacttaga tcattatata atacagtagc aaccctctat tgtgtgcatc     1440

aaaggataga gataaaagac accaaggaag ctttagacaa gatagaggaa gagcaaaaca     1500

aaagtaagac caccgcacag caagcggccg ctgatcttca gacctggagg aggagatatg     1560

agggacaatt ggagaagtga attatataaa tataaagtag taaaaattga accattagga     1620

gtagcaccca ccaaggcaaa gagaagagtg gtgcagagag aaaaaagagc agtgggaata     1680

ggagctttgt tccttgggtt cttgggagca gcaggaagca ctatgggcgc agcgtcaatg     1740

acgctgacgg tacaggccag acaattattg tctggtatag tgcagcagca gaacaatttg     1800

ctgagggcta ttgaggcgca acagcatctg ttgcaactca cagtctgggg catcaagcag     1860

ctccaggcaa gaatcctggc tgtggaaaga tacctaaagg atcaacagct cctggggatt     1920

tggggttgct ctggaaaact catttgcacc actgctgtgc cttggaatgc tagttggagt     1980

aataaatctc tggaacagat ttggaatcac acgacctgga tggagtggga cagagaaatt     2040

aacaattaca caagcttaat acactcctta attgaagaat cgcaaaacca gcaagaaaag     2100

aatgaacaag aattattgga attagataaa tgggcaagtt tgtggaattg gtttaacata     2160

acaaattggc tgtggtatat aaaattattc ataatgatag taggaggctt ggtaggttta     2220

agaatagttt ttgctgtact ttctatagtg aatagagtta ggcagggata ttcaccatta     2280

tcgtttcaga cccacctccc aaccccgagg ggacccgaca ggcccgaagg aatagaagaa     2340

gaaggtggag agagagacag agacagatcc attcgattag tgaacggatc ggcactgcgt     2400

gcgccaattc tgcagacaaa tggcagtatt catccacaat tttaaaagaa aaggggggat     2460

tggggggtac agtgcagggg aaagaatagt agacataata gcaacagaca tacaaactaa     2520

agaattacaa aaacaaatta caaaaattca aaattttcgg gtttattaca gggacagcag     2580

agatccagtt tggttaatta agtgtctaga ctgcagaggg ccctgcgtat gagtgcaagt     2640

gggttttagg accaggatga ggcggggtgg gggtgcctac ctgacgaccg accccgaccc     2700

actggacaag cacccaaccc ccattcccca aattgcgcat cccctatcag agagggggag     2760

gggaaacagg atgcggcgag gcgcgtgcgc actgccagct tcagcaccgc ggacagtgcc     2820

ttcgcccccg cctggcggcg cgcgccaccg ccgcctcagc actgaaggcg cgctgacgtc     2880

actcgccggt cccccgcaaa ctccccttcc cggccacctt ggtcgcgtcc gcgccgccgc     2940

cggcccagcc ggaccgcacc acgcgaggcg cgagataggg gggcacgggc gcgaccatct     3000

gcgctgcggc gccggcgact cagcgctgcc tcagtctgcg gtgggcagcg gaggagtcgt     3060

gtcgtgcctg agagcgcagt cgagaaaccg gtgccaccat gggagtcaaa gttctgtttg     3120

ccctgatctg catcgctgtg gccgaggcca agcccaccga gaacaacgaa gacttcaaca     3180

tcgtggccgt ggccagcaac ttcgcgacca cggatctcga tgctgaccgc gggaagttgc     3240

ccggcaagaa gctgccgctg gaggtgctca aagagatgga agccaatgcc cggaaagctg     3300

gctgcaccag gggctgtctg atctgcctgt cccacatcaa gtgcacgccc aagatgaaga     3360

agttcatccc aggacgctgc cacacctacg aaggcgacaa agagtccgca cagggcggca     3420

taggcgaggc gatcgtcgac attcctgaga ttcctgggtt caaggacttg gagcccatgg     3480

agcagttcat cgcacaggtc gatctgtgtg tggactgcac aactggctgc ctcaaagggc     3540

ttgccaacgt gcagtgttct gacctgctca agaagtggct gccgcaacgc tgtgcgacct     3600

ttgccagcaa gatccagggc caggtggaca agatcaaggg ggccggtggt gacggggatc     3660

cactagtcca gtgtggtgga attgccaccg gtgccaccat ggactatggc ggcgctttgt     3720

ctgccgtcgg acgcgaactt ttgttcgtta ctaatcctgt ggtggtgaac gggtccgtcc     3780

tggtccctga ggatcaatgt tactgtgccg gatggattga atctcgcggc acgaacggcg     3840

ctcagaccgc gtcaaatgtc ctgcagtggc ttgcagcagg attcagcatt ttgctgctga     3900

tgttctatgc ctaccaaacc tggaaatcta catgcggctg ggaggagatc tatgtgtgcg     3960

ccattgaaat ggttaaggtg attctcgagt tcttttttga gtttaagaat ccctctatgc     4020

tctaccttgc cacaggacac cgggtgcagt ggctgcgcta tgcagagtgg ctgctcactt     4080

gtcctgtcat ccttatccgc ctgagcaacc tcaccggcct gagcaacgac tacagcagga     4140

gaaccatggg actccttgtc tcagacatcg ggactatcgt gtggggggct accagcgcca     4200

tggcaaccgg ctatgttaaa gtcatcttct tttgtcttgg attgtgctat ggcgcgaaca     4260

cattttttca cgccgccaaa gcatatatcg agggttatca tactgtgcca aagggtcggt     4320

gccgccaggt cgtgaccggc atggcatggc tgtttttcgt gagctggggt atgttcccaa     4380

ttctcttcat tttggggccc gaaggttttg gcgtcctgag cgtctatggc tccaccgtag     4440

gtcacacgat tattgatctg atgagtaaaa attgttgggg gttgttggga cactacctgc     4500

gcgtcctgat ccacgagcac atattgattc acggagatat ccgcaaaacc accaaactga     4560

acatcggcgg aacggagatc gaggtcgaga ctctcgtcga agacgaagcc gaggccggag     4620

ccgtgccagc ggccgccacc atggtgagca agggcgagga gctgttcacc ggggtggtgc     4680

ccatcctggt cgagctggac ggcgacgtaa acggccacaa gttcagcgtg tccggcgagg     4740

gcgagggcga tgccacctac ggcaagctga ccctgaagtt catctgcacc accggcaagc     4800

tgcccgtgcc ctggcccacc ctcgtgacca ccttcggcta cggcctgcag tgcttcgccc     4860

gctaccccga ccacatgaag cagcacgact tcttcaagtc cgccatgccc gaaggctacg     4920

tccaggagcg caccatcttc ttcaaggacg acggcaacta caagacccgc gccgaggtga     4980

agttcgaggg cgacaccctg gtgaaccgca tcgagctgaa gggcatcgac ttcaaggagg     5040

acggcaacat cctggggcac aagctggagt acaactacaa cagccacaac gtctatatca     5100

tggccgacaa gcagaagaac ggcatcaagg tgaacttcaa gatccgccac aacatcgagg     5160

acggcagcgt gcagctcgcc gaccactacc agcagaacac ccccatcggc gacggccccg     5220

tgctgctgcc cgacaaccac tacctgagct accagtccgc cctgagcaaa gaccccaacg     5280

agaagcgcga tcacatggtc ctgctggagt tcgtgaccgc cgccgggatc actctcggca     5340

tggacgagct gtacaagtaa gaattcgata tcaagcttat cgataatcaa cctctggatt     5400

acaaaatttg tgaaagattg actggtattc ttaactatgt tgctcctttt acgctatgtg     5460

gatacgctgc tttaatgcct ttgtatcatg ctattgcttc ccgtatggct ttcattttct     5520

cctccttgta taaatcctgg ttgctgtctc tttatgagga gttgtggccc gttgtcaggc     5580

aacgtggcgt ggtgtgcact gtgtttgctg acgcaacccc cactggttgg ggcattgcca     5640

ccacctgtca gctcctttcc gggactttcg ctttccccct ccctattgcc acggcggaac     5700

tcatcgccgc ctgccttgcc cgctgctgga caggggctcg gctgttgggc actgacaatt     5760

ccgtggtgtt gtcggggaaa tcatcgtcct ttccttggct gctcgcctgt gttgccacct     5820

ggattctgcg cgggacgtcc ttctgctacg tcccttcggc cctcaatcca gcggaccttc     5880

cttcccgcgg cctgctgccg gctctgcggc ctcttccgcg tcttcgcctt cgccctcaga     5940

cgagtcggat ctccctttgg gccgcctccc cgcatcgata ccgtcgacct cgagacctag     6000

aaaaacatgg agcaatcaca agtagcaata cagcagctac caatgctgat tgtgcctggc     6060

tagaagcaca agaggaggag gaggtgggtt ttccagtcac acctcaggta cctttaagac     6120

caatgactta caaggcagct gtagatctta gccacttttt aaaagaaaag gggggactgg     6180

aagggctaat tcactcccaa cgaagacaag atatccttga tctgtggatc taccacacac     6240

aaggctactt ccctgattgg cagaactaca caccagggcc agggatcaga tatccactga     6300

cctttggatg gtgctacaag ctagtaccag ttgagcaaga gaaggtagaa gaagccaatg     6360

aaggagagaa cacccgcttg ttacaccctg tgagcctgca tgggatggat gacccggaga     6420

gagaagtatt agagtggagg tttgacagcc gcctagcatt tcatcacatg gcccgagagc     6480

tgcatccgga ctgtactggg tctctctggt tagaccagat ctgagcctgg gagctctctg     6540

gctaactagg gaacccactg cttaagcctc aataaagctt gccttgagtg cttcaagtag     6600

tgtgtgcccg tctgttgtgt gactctggta actagagatc cctcagaccc ttttagtcag     6660

tgtggaaaat ctctagcagg gcccgtttaa acccgctgat cagcctcgac tgtgccttct     6720

agttgccagc catctgttgt ttgcccctcc cccgtgcctt ccttgaccct ggaaggtgcc     6780

actcccactg tcctttccta ataaaatgag gaaattgcat cgcattgtct gagtaggtgt     6840

cattctattc tggggggtgg ggtggggcag gacagcaagg gggaggattg ggaagacaat     6900

agcaggcatg ctggggatgc ggtgggctct atggcttctg aggcggaaag aaccagctgg     6960

ggctctaggg ggtatcccca cgcgccctgt agcggcgcat taagcgcggc gggtgtggtg     7020

gttacgcgca gcgtgaccgc tacacttgcc agcgccctag cgcccgctcc tttcgctttc     7080

ttcccttcct ttctcgccac gttcgccggc tttccccgtc aagctctaaa tcgggggctc     7140

cctttagggt tccgatttag tgctttacgg cacctcgacc ccaaaaaact tgattagggt     7200

gatggttcac gtagtgggcc atcgccctga tagacggttt ttcgcccttt gacgttggag     7260

tccacgttct ttaatagtgg actcttgttc caaactggaa caacactcaa ccctatctcg     7320

gtctattctt ttgatttata agggattttg ccgatttcgg cctattggtt aaaaaatgag     7380

ctgatttaac aaaaatttaa cgcgaattaa ttctgtggaa tgtgtgtcag ttagggtgtg     7440

gaaagtcccc aggctcccca gcaggcagaa gtatgcaaag catgcatctc aattagtcag     7500

caaccaggtg tggaaagtcc ccaggctccc cagcaggcag aagtatgcaa agcatgcatc     7560

tcaattagtc agcaaccata gtcccgcccc taactccgcc catcccgccc ctaactccgc     7620

ccagttccgc ccattctccg ccccatggct gactaatttt ttttatttat gcagaggccg     7680

aggccgcctc tgcctctgag ctattccaga agtagtgagg aggctttttt ggaggcctag     7740

gcttttgcaa aaagctcccg ggagcttgta tatccatttt cggatctgat cagcacgtgt     7800

tgacaattaa tcatcggcat agtatatcgg catagtataa tacgacaagg tgaggaacta     7860

aaccatggcc aagttgacca gtgccgttcc ggtgctcacc gcgcgcgacg tcgccggagc     7920

ggtcgagttc tggaccgacc ggctcgggtt ctcccgggac ttcgtggagg acgacttcgc     7980

cggtgtggtc cgggacgacg tgaccctgtt catcagcgcg gtccaggacc aggtggtgcc     8040

ggacaacacc ctggcctggg tgtgggtgcg cggcctggac gagctgtacg ccgagtggtc     8100

ggaggtcgtg tccacgaact tccgggacgc ctccgggccg gccatgaccg agatcggcga     8160

gcagccgtgg gggcgggagt tcgccctgcg cgacccggcc ggcaactgcg tgcacttcgt     8220

ggccgaggag caggactgac acgtgctacg agatttcgat tccaccgccg ccttctatga     8280

aaggttgggc ttcggaatcg ttttccggga cgccggctgg atgatcctcc agcgcgggga     8340

tctcatgctg gagttcttcg cccaccccaa cttgtttatt gcagcttata atggttacaa     8400

ataaagcaat agcatcacaa atttcacaaa taaagcattt ttttcactgc attctagttg     8460

tggtttgtcc aaactcatca atgtatctta tcatgtctgt ataccgtcga cctctagcta     8520

gagcttggcg taatcatggt catagctgtt tcctgtgtga aattgttatc cgctcacaat     8580

tccacacaac atacgagccg gaagcataaa gtgtaaagcc tggggtgcct aatgagtgag     8640

ctaactcaca ttaattgcgt tgcgctcact gcccgctttc cagtcgggaa acctgtcgtg     8700

ccagctgcat taatgaatcg gccaacgcgc ggggagaggc ggtttgcgta ttgggcgctc     8760

ttccgcttcc tcgctcactg actcgctgcg ctcggtcgtt cggctgcggc gagcggtatc     8820

agctcactca aaggcggtaa tacggttatc cacagaatca ggggataacg caggaaagaa     8880

catgtgagca aaaggccagc aaaaggccag gaaccgtaaa aaggccgcgt tgctggcgtt     8940

tttccatagg ctccgccccc ctgacgagca tcacaaaaat cgacgctcaa gtcagaggtg     9000

gcgaaacccg acaggactat aaagatacca ggcgtttccc cctggaagct ccctcgtgcg     9060

ctctcctgtt ccgaccctgc cgcttaccgg atacctgtcc gcctttctcc cttcgggaag     9120

cgtggcgctt tctcatagct cacgctgtag gtatctcagt tcggtgtagg tcgttcgctc     9180

caagctgggc tgtgtgcacg aaccccccgt tcagcccgac cgctgcgcct tatccggtaa     9240

ctatcgtctt gagtccaacc cggtaagaca cgacttatcg ccactggcag cagccactgg     9300

taacaggatt agcagagcga ggtatgtagg cggtgctaca gagttcttga agtggtggcc     9360

taactacggc tacactagaa gaacagtatt tggtatctgc gctctgctga agccagttac     9420

cttcggaaaa agagttggta gctcttgatc cggcaaacaa accaccgctg gtagcggtgg     9480

tttttttgtt tgcaagcagc agattacgcg cagaaaaaaa ggatctcaag aagatccttt     9540

gatcttttct acggggtctg acgctcagtg gaacgaaaac tcacgttaag ggattttggt     9600

catgagatta tcaaaaagga tcttcaccta gatcctttta aattaaaaat gaagttttaa     9660

atcaatctaa agtatatatg agtaaacttg gtctgacagt taccaatgct taatcagtga     9720

ggcacctatc tcagcgatct gtctatttcg ttcatccata gttgcctgac tccccgtcgt     9780

gtagataact acgatacggg agggcttacc atctggcccc agtgctgcaa tgataccgcg     9840

agacccacgc tcaccggctc cagatttatc agcaataaac cagccagccg gaagggccga     9900

gcgcagaagt ggtcctgcaa ctttatccgc ctccatccag tctattaatt gttgccggga     9960

agctagagta agtagttcgc cagttaatag tttgcgcaac gttgttgcca ttgctacagg    10020

catcgtggtg tcacgctcgt cgtttggtat ggcttcattc agctccggtt cccaacgatc    10080

aaggcgagtt acatgatccc ccatgttgtg caaaaaagcg gttagctcct tcggtcctcc    10140

gatcgttgtc agaagtaagt tggccgcagt gttatcactc atggttatgg cagcactgca    10200

taattctctt actgtcatgc catccgtaag atgcttttct gtgactggtg agtactcaac    10260

caagtcattc tgagaatagt gtatgcggcg accgagttgc tcttgcccgg cgtcaatacg    10320

ggataatacc gcgccacata gcagaacttt aaaagtgctc atcattggaa aacgttcttc    10380

ggggcgaaaa ctctcaagga tcttaccgct gttgagatcc agttcgatgt aacccactcg    10440

tgcacccaac tgatcttcag catcttttac tttcaccagc gtttctgggt gagcaaaaac    10500

aggaaggcaa aatgccgcaa aaaagggaat aagggcgaca cggaaatgtt gaatactcat    10560

actcttcctt tttcaatatt attgaagcat ttatcagggt tattgtctca tgagcggata    10620

catatttgaa tgtatttaga aaaataaaca aataggggtt ccgcgcacat ttccccgaaa    10680

agtgccacct gac                                                       10693


<210>  5
<211>  10093
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  5
gtcgacggat cgggagatct cccgatcccc tatggtgcac tctcagtaca atctgctctg       60

atgccgcata gttaagccag tatctgctcc ctgcttgtgt gttggaggtc gctgagtagt      120

gcgcgagcaa aatttaagct acaacaaggc aaggcttgac cgacaattgc atgaagaatc      180

tgcttagggt taggcgtttt gcgctgcttc gcgatgtacg ggccagatat acgcgttgac      240

attgattatt gactagttat taatagtaat caattacggg gtcattagtt catagcccat      300

atatggagtt ccgcgttaca taacttacgg taaatggccc gcctggctga ccgcccaacg      360

acccccgccc attgacgtca ataatgacgt atgttcccat agtaacgcca atagggactt      420

tccattgacg tcaatgggtg gagtatttac ggtaaactgc ccacttggca gtacatcaag      480

tgtatcatat gccaagtacg ccccctattg acgtcaatga cggtaaatgg cccgcctggc      540

attatgccca gtacatgacc ttatgggact ttcctacttg gcagtacatc tacgtattag      600

tcatcgctat taccatggtg atgcggtttt ggcagtacat caatgggcgt ggatagcggt      660

ttgactcacg gggatttcca agtctccacc ccattgacgt caatgggagt ttgttttggc      720

accaaaatca acgggacttt ccaaaatgtc gtaacaactc cgccccattg acgcaaatgg      780

gcggtaggcg tgtacggtgg gaggtctata taagcagcgc gttttgcctg tactgggtct      840

ctctggttag accagatctg agcctgggag ctctctggct aactagggaa cccactgctt      900

aagcctcaat aaagcttgcc ttgagtgctt caagtagtgt gtgcccgtct gttgtgtgac      960

tctggtaact agagatccct cagacccttt tagtcagtgt ggaaaatctc tagcagtggc     1020

gcccgaacag ggacttgaaa gcgaaaggga aaccagagga gctctctcga cgcaggactc     1080

ggcttgctga agcgcgcacg gcaagaggcg aggggcggcg actggtgagt acgccaaaaa     1140

ttttgactag cggaggctag aaggagagag atgggtgcga gagcgtcagt attaagcggg     1200

ggagaattag atcgcgatgg gaaaaaattc ggttaaggcc agggggaaag aaaaaatata     1260

aattaaaaca tatagtatgg gcaagcaggg agctagaacg attcgcagtt aatcctggcc     1320

tgttagaaac atcagaaggc tgtagacaaa tactgggaca gctacaacca tcccttcaga     1380

caggatcaga agaacttaga tcattatata atacagtagc aaccctctat tgtgtgcatc     1440

aaaggataga gataaaagac accaaggaag ctttagacaa gatagaggaa gagcaaaaca     1500

aaagtaagac caccgcacag caagcggccg ctgatcttca gacctggagg aggagatatg     1560

agggacaatt ggagaagtga attatataaa tataaagtag taaaaattga accattagga     1620

gtagcaccca ccaaggcaaa gagaagagtg gtgcagagag aaaaaagagc agtgggaata     1680

ggagctttgt tccttgggtt cttgggagca gcaggaagca ctatgggcgc agcgtcaatg     1740

acgctgacgg tacaggccag acaattattg tctggtatag tgcagcagca gaacaatttg     1800

ctgagggcta ttgaggcgca acagcatctg ttgcaactca cagtctgggg catcaagcag     1860

ctccaggcaa gaatcctggc tgtggaaaga tacctaaagg atcaacagct cctggggatt     1920

tggggttgct ctggaaaact catttgcacc actgctgtgc cttggaatgc tagttggagt     1980

aataaatctc tggaacagat ttggaatcac acgacctgga tggagtggga cagagaaatt     2040

aacaattaca caagcttaat acactcctta attgaagaat cgcaaaacca gcaagaaaag     2100

aatgaacaag aattattgga attagataaa tgggcaagtt tgtggaattg gtttaacata     2160

acaaattggc tgtggtatat aaaattattc ataatgatag taggaggctt ggtaggttta     2220

agaatagttt ttgctgtact ttctatagtg aatagagtta ggcagggata ttcaccatta     2280

tcgtttcaga cccacctccc aaccccgagg ggacccgaca ggcccgaagg aatagaagaa     2340

gaaggtggag agagagacag agacagatcc attcgattag tgaacggatc ggcactgcgt     2400

gcgccaattc tgcagacaaa tggcagtatt catccacaat tttaaaagaa aaggggggat     2460

tggggggtac agtgcagggg aaagaatagt agacataata gcaacagaca tacaaactaa     2520

agaattacaa aaacaaatta caaaaattca aaattttcgg gtttattaca gggacagcag     2580

agatccagtt tggttaatta agtgtctaga ctgcagaggg ccctgcgtat gagtgcaagt     2640

gggttttagg accaggatga ggcggggtgg gggtgcctac ctgacgaccg accccgaccc     2700

actggacaag cacccaaccc ccattcccca aattgcgcat cccctatcag agagggggag     2760

gggaaacagg atgcggcgag gcgcgtgcgc actgccagct tcagcaccgc ggacagtgcc     2820

ttcgcccccg cctggcggcg cgcgccaccg ccgcctcagc actgaaggcg cgctgacgtc     2880

actcgccggt cccccgcaaa ctccccttcc cggccacctt ggtcgcgtcc gcgccgccgc     2940

cggcccagcc ggaccgcacc acgcgaggcg cgagataggg gggcacgggc gcgaccatct     3000

gcgctgcggc gccggcgact cagcgctgcc tcagtctgcg gtgggcagcg gaggagtcgt     3060

gtcgtgcctg agagcgcagt cgagaaaccg gtgccaccat ggactatggc ggcgctttgt     3120

ctgccgtcgg acgcgaactt ttgttcgtta ctaatcctgt ggtggtgaac gggtccgtcc     3180

tggtccctga ggatcaatgt tactgtgccg gatggattga atctcgcggc acgaacggcg     3240

ctcagaccgc gtcaaatgtc ctgcagtggc ttgcagcagg attcagcatt ttgctgctga     3300

tgttctatgc ctaccaaacc tggaaatcta catgcggctg ggaggagatc tatgtgtgcg     3360

ccattgaaat ggttaaggtg attctcgagt tcttttttga gtttaagaat ccctctatgc     3420

tctaccttgc cacaggacac cgggtgcagt ggctgcgcta tgcagagtgg ctgctcactt     3480

gtcctgtcat ccttatccgc ctgagcaacc tcaccggcct gagcaacgac tacagcagga     3540

gaaccatggg actccttgtc tcagacatcg ggactatcgt gtggggggct accagcgcca     3600

tggcaaccgg ctatgttaaa gtcatcttct tttgtcttgg attgtgctat ggcgcgaaca     3660

cattttttca cgccgccaaa gcatatatcg agggttatca tactgtgcca aagggtcggt     3720

gccgccaggt cgtgaccggc atggcatggc tgtttttcgt gagctggggt atgttcccaa     3780

ttctcttcat tttggggccc gaaggttttg gcgtcctgag cgtctatggc tccaccgtag     3840

gtcacacgat tattgatctg atgagtaaaa attgttgggg gttgttggga cactacctgc     3900

gcgtcctgat ccacgagcac atattgattc acggagatat ccgcaaaacc accaaactga     3960

acatcggcgg aacggagatc gaggtcgaga ctctcgtcga agacgaagcc gaggccggag     4020

ccgtgccagc ggccgccacc atggtgagca agggcgagga gctgttcacc ggggtggtgc     4080

ccatcctggt cgagctggac ggcgacgtaa acggccacaa gttcagcgtg tccggcgagg     4140

gcgagggcga tgccacctac ggcaagctga ccctgaagtt catctgcacc accggcaagc     4200

tgcccgtgcc ctggcccacc ctcgtgacca ccttcggcta cggcctgcag tgcttcgccc     4260

gctaccccga ccacatgaag cagcacgact tcttcaagtc cgccatgccc gaaggctacg     4320

tccaggagcg caccatcttc ttcaaggacg acggcaacta caagacccgc gccgaggtga     4380

agttcgaggg cgacaccctg gtgaaccgca tcgagctgaa gggcatcgac ttcaaggagg     4440

acggcaacat cctggggcac aagctggagt acaactacaa cagccacaac gtctatatca     4500

tggccgacaa gcagaagaac ggcatcaagg tgaacttcaa gatccgccac aacatcgagg     4560

acggcagcgt gcagctcgcc gaccactacc agcagaacac ccccatcggc gacggccccg     4620

tgctgctgcc cgacaaccac tacctgagct accagtccgc cctgagcaaa gaccccaacg     4680

agaagcgcga tcacatggtc ctgctggagt tcgtgaccgc cgccgggatc actctcggca     4740

tggacgagct gtacaagtaa gaattcgata tcaagcttat cgataatcaa cctctggatt     4800

acaaaatttg tgaaagattg actggtattc ttaactatgt tgctcctttt acgctatgtg     4860

gatacgctgc tttaatgcct ttgtatcatg ctattgcttc ccgtatggct ttcattttct     4920

cctccttgta taaatcctgg ttgctgtctc tttatgagga gttgtggccc gttgtcaggc     4980

aacgtggcgt ggtgtgcact gtgtttgctg acgcaacccc cactggttgg ggcattgcca     5040

ccacctgtca gctcctttcc gggactttcg ctttccccct ccctattgcc acggcggaac     5100

tcatcgccgc ctgccttgcc cgctgctgga caggggctcg gctgttgggc actgacaatt     5160

ccgtggtgtt gtcggggaaa tcatcgtcct ttccttggct gctcgcctgt gttgccacct     5220

ggattctgcg cgggacgtcc ttctgctacg tcccttcggc cctcaatcca gcggaccttc     5280

cttcccgcgg cctgctgccg gctctgcggc ctcttccgcg tcttcgcctt cgccctcaga     5340

cgagtcggat ctccctttgg gccgcctccc cgcatcgata ccgtcgacct cgagacctag     5400

aaaaacatgg agcaatcaca agtagcaata cagcagctac caatgctgat tgtgcctggc     5460

tagaagcaca agaggaggag gaggtgggtt ttccagtcac acctcaggta cctttaagac     5520

caatgactta caaggcagct gtagatctta gccacttttt aaaagaaaag gggggactgg     5580

aagggctaat tcactcccaa cgaagacaag atatccttga tctgtggatc taccacacac     5640

aaggctactt ccctgattgg cagaactaca caccagggcc agggatcaga tatccactga     5700

cctttggatg gtgctacaag ctagtaccag ttgagcaaga gaaggtagaa gaagccaatg     5760

aaggagagaa cacccgcttg ttacaccctg tgagcctgca tgggatggat gacccggaga     5820

gagaagtatt agagtggagg tttgacagcc gcctagcatt tcatcacatg gcccgagagc     5880

tgcatccgga ctgtactggg tctctctggt tagaccagat ctgagcctgg gagctctctg     5940

gctaactagg gaacccactg cttaagcctc aataaagctt gccttgagtg cttcaagtag     6000

tgtgtgcccg tctgttgtgt gactctggta actagagatc cctcagaccc ttttagtcag     6060

tgtggaaaat ctctagcagg gcccgtttaa acccgctgat cagcctcgac tgtgccttct     6120

agttgccagc catctgttgt ttgcccctcc cccgtgcctt ccttgaccct ggaaggtgcc     6180

actcccactg tcctttccta ataaaatgag gaaattgcat cgcattgtct gagtaggtgt     6240

cattctattc tggggggtgg ggtggggcag gacagcaagg gggaggattg ggaagacaat     6300

agcaggcatg ctggggatgc ggtgggctct atggcttctg aggcggaaag aaccagctgg     6360

ggctctaggg ggtatcccca cgcgccctgt agcggcgcat taagcgcggc gggtgtggtg     6420

gttacgcgca gcgtgaccgc tacacttgcc agcgccctag cgcccgctcc tttcgctttc     6480

ttcccttcct ttctcgccac gttcgccggc tttccccgtc aagctctaaa tcgggggctc     6540

cctttagggt tccgatttag tgctttacgg cacctcgacc ccaaaaaact tgattagggt     6600

gatggttcac gtagtgggcc atcgccctga tagacggttt ttcgcccttt gacgttggag     6660

tccacgttct ttaatagtgg actcttgttc caaactggaa caacactcaa ccctatctcg     6720

gtctattctt ttgatttata agggattttg ccgatttcgg cctattggtt aaaaaatgag     6780

ctgatttaac aaaaatttaa cgcgaattaa ttctgtggaa tgtgtgtcag ttagggtgtg     6840

gaaagtcccc aggctcccca gcaggcagaa gtatgcaaag catgcatctc aattagtcag     6900

caaccaggtg tggaaagtcc ccaggctccc cagcaggcag aagtatgcaa agcatgcatc     6960

tcaattagtc agcaaccata gtcccgcccc taactccgcc catcccgccc ctaactccgc     7020

ccagttccgc ccattctccg ccccatggct gactaatttt ttttatttat gcagaggccg     7080

aggccgcctc tgcctctgag ctattccaga agtagtgagg aggctttttt ggaggcctag     7140

gcttttgcaa aaagctcccg ggagcttgta tatccatttt cggatctgat cagcacgtgt     7200

tgacaattaa tcatcggcat agtatatcgg catagtataa tacgacaagg tgaggaacta     7260

aaccatggcc aagttgacca gtgccgttcc ggtgctcacc gcgcgcgacg tcgccggagc     7320

ggtcgagttc tggaccgacc ggctcgggtt ctcccgggac ttcgtggagg acgacttcgc     7380

cggtgtggtc cgggacgacg tgaccctgtt catcagcgcg gtccaggacc aggtggtgcc     7440

ggacaacacc ctggcctggg tgtgggtgcg cggcctggac gagctgtacg ccgagtggtc     7500

ggaggtcgtg tccacgaact tccgggacgc ctccgggccg gccatgaccg agatcggcga     7560

gcagccgtgg gggcgggagt tcgccctgcg cgacccggcc ggcaactgcg tgcacttcgt     7620

ggccgaggag caggactgac acgtgctacg agatttcgat tccaccgccg ccttctatga     7680

aaggttgggc ttcggaatcg ttttccggga cgccggctgg atgatcctcc agcgcgggga     7740

tctcatgctg gagttcttcg cccaccccaa cttgtttatt gcagcttata atggttacaa     7800

ataaagcaat agcatcacaa atttcacaaa taaagcattt ttttcactgc attctagttg     7860

tggtttgtcc aaactcatca atgtatctta tcatgtctgt ataccgtcga cctctagcta     7920

gagcttggcg taatcatggt catagctgtt tcctgtgtga aattgttatc cgctcacaat     7980

tccacacaac atacgagccg gaagcataaa gtgtaaagcc tggggtgcct aatgagtgag     8040

ctaactcaca ttaattgcgt tgcgctcact gcccgctttc cagtcgggaa acctgtcgtg     8100

ccagctgcat taatgaatcg gccaacgcgc ggggagaggc ggtttgcgta ttgggcgctc     8160

ttccgcttcc tcgctcactg actcgctgcg ctcggtcgtt cggctgcggc gagcggtatc     8220

agctcactca aaggcggtaa tacggttatc cacagaatca ggggataacg caggaaagaa     8280

catgtgagca aaaggccagc aaaaggccag gaaccgtaaa aaggccgcgt tgctggcgtt     8340

tttccatagg ctccgccccc ctgacgagca tcacaaaaat cgacgctcaa gtcagaggtg     8400

gcgaaacccg acaggactat aaagatacca ggcgtttccc cctggaagct ccctcgtgcg     8460

ctctcctgtt ccgaccctgc cgcttaccgg atacctgtcc gcctttctcc cttcgggaag     8520

cgtggcgctt tctcatagct cacgctgtag gtatctcagt tcggtgtagg tcgttcgctc     8580

caagctgggc tgtgtgcacg aaccccccgt tcagcccgac cgctgcgcct tatccggtaa     8640

ctatcgtctt gagtccaacc cggtaagaca cgacttatcg ccactggcag cagccactgg     8700

taacaggatt agcagagcga ggtatgtagg cggtgctaca gagttcttga agtggtggcc     8760

taactacggc tacactagaa gaacagtatt tggtatctgc gctctgctga agccagttac     8820

cttcggaaaa agagttggta gctcttgatc cggcaaacaa accaccgctg gtagcggtgg     8880

tttttttgtt tgcaagcagc agattacgcg cagaaaaaaa ggatctcaag aagatccttt     8940

gatcttttct acggggtctg acgctcagtg gaacgaaaac tcacgttaag ggattttggt     9000

catgagatta tcaaaaagga tcttcaccta gatcctttta aattaaaaat gaagttttaa     9060

atcaatctaa agtatatatg agtaaacttg gtctgacagt taccaatgct taatcagtga     9120

ggcacctatc tcagcgatct gtctatttcg ttcatccata gttgcctgac tccccgtcgt     9180

gtagataact acgatacggg agggcttacc atctggcccc agtgctgcaa tgataccgcg     9240

agacccacgc tcaccggctc cagatttatc agcaataaac cagccagccg gaagggccga     9300

gcgcagaagt ggtcctgcaa ctttatccgc ctccatccag tctattaatt gttgccggga     9360

agctagagta agtagttcgc cagttaatag tttgcgcaac gttgttgcca ttgctacagg     9420

catcgtggtg tcacgctcgt cgtttggtat ggcttcattc agctccggtt cccaacgatc     9480

aaggcgagtt acatgatccc ccatgttgtg caaaaaagcg gttagctcct tcggtcctcc     9540

gatcgttgtc agaagtaagt tggccgcagt gttatcactc atggttatgg cagcactgca     9600

taattctctt actgtcatgc catccgtaag atgcttttct gtgactggtg agtactcaac     9660

caagtcattc tgagaatagt gtatgcggcg accgagttgc tcttgcccgg cgtcaatacg     9720

ggataatacc gcgccacata gcagaacttt aaaagtgctc atcattggaa aacgttcttc     9780

ggggcgaaaa ctctcaagga tcttaccgct gttgagatcc agttcgatgt aacccactcg     9840

tgcacccaac tgatcttcag catcttttac tttcaccagc gtttctgggt gagcaaaaac     9900

aggaaggcaa aatgccgcaa aaaagggaat aagggcgaca cggaaatgtt gaatactcat     9960

actcttcctt tttcaatatt attgaagcat ttatcagggt tattgtctca tgagcggata    10020

catatttgaa tgtatttaga aaaataaaca aataggggtt ccgcgcacat ttccccgaaa    10080

agtgccacct gac                                                       10093


<210>  6
<211>  7672
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  6
gacggatcgg gagatctccc gatcccctat ggtcgactct cagtacaatc tgctctgatg       60

ccgcatagtt aagccagtat ctgctccctg cttgtgtgtt ggaggtcgct gagtagtgcg      120

cgagcaaaat ttaagctaca acaaggcaag gcttgaccga caattgcatg aagaatctgc      180

ttagggttag gcgttttgcg ctgcttcgcg atgtacgggc cagatatacg cgttgacatt      240

gattattgac tagttattaa tagtaatcaa ttacggggtc attagttcat agcccatata      300

tggagttccg cgttacataa cttacggtaa atggcccgcc tggctgaccg cccaacgacc      360

cccgcccatt gacgtcaata atgacgtatg ttcccatagt aacgccaata gggactttcc      420

attgacgtca atgggtggag tatttacggt aaactgccca cttggcagta catcaagtgt      480

atcatatgcc aagtacgccc cctattgacg tcaatgacgg taaatggccc gcctggcatt      540

atgcccagta catgacctta tgggactttc ctacttggca gtacatctac gtattagtca      600

tcgctattac catggtgatg cggttttggc agtacatcaa tgggcgtgga tagcggtttg      660

actcacgggg atttccaagt ctccacccca ttgacgtcaa tgggagtttg ttttggcacc      720

aaaatcaacg ggactttcca aaatgtcgta acaactccgc cccattgacg caaatgggcg      780

gtaggcgtgt acggtgggag gtctatataa gcagagctct ctggctaact agagaaccca      840

ctgcttactg gcttatcgaa attaatacga ctcactatag ggagacccaa gctggctagt      900

taagcttgcc accatgggag tcaaagttct gtttgccctg atctgcatcg ctgtggccga      960

ggccaagccc accgagaaca acgaagactt caacatcgtg gccgtggcca gcaacttcgc     1020

gaccacggat ctcgatgctg accgcgggaa gttgcccggc aagaagctgc cgctggaggt     1080

gctcaaagag atggaagcca atgcccggaa agctggctgc accaggggct gtctgatctg     1140

cctgtcccac atcaagtgca cgcccaagat gaagaagttc atcccaggac gctgccacac     1200

ctacgaaggc gacaaagagt ccgcacaggg cggcataggc gaggcgatcg tcgacattcc     1260

tgagattcct gggttcaagg acttggagcc catggagcag ttcatcgcac aggtcgatct     1320

gtgtgtggac tgcacaactg gctgcctcaa agggcttgcc aacgtgcagt gttctgacct     1380

gctcaagaag tggctgccgc aacgctgtgc gacctttgcc agcaagatcc agggccaggt     1440

ggacaagatc aagggggccg gtggtgacgg cgacccacta gtccagtgtg gtggaattgc     1500

cggatccgcc accatggatt accctgttgc tagaagcctc atagttcgct acccaaccga     1560

cctcggaaac ggcaccgtct gcatgccaag aggacagtgt tactgtgaag gttggcttcg     1620

gagtcgcggc acttccattg aaaagacaat agcaattact cttcagtggg tagtctttgc     1680

tttgtcagtg gcttgcctgg ggtggtatgc gtatcaagcg tggcgagcta cctgcggatg     1740

ggaggaggtt tacgtagcct tgatagaaat gatgaaaagc atcatcgagg ccttccacga     1800

gttcgacagc cctgcaacac tgtggctgtc ttcagggaac ggcgtagttt ggatgcggta     1860

tggcgaatgg ctcctcacct gcccggtcct tctgatccat ctgagcaacc tcacaggcct     1920

gaaggacgat tatagcaaaa ggactatggg cctgttggtt tctgatgtgg gatgcatcgt     1980

gtggggcgca accagcgcca tgtgtacggg gtggacgaag atcctgttct tcctcatctc     2040

attgagctat ggtatgtata cctattttca tgctgctaaa gtttatatcg aagcattcca     2100

cacagttcca aaagggattt gtcgagaact ggtccgagtg atggcctgga cattctttgt     2160

ggcttgggga atgtttccag tcctgtttct gctgggcacg gaaggattcg gtcatatcag     2220

cccttatgga tctgccattg ggcactccat cctcgacctg attgcaaaga acatgtgggg     2280

tgtgctgggg aattacctgc gcgtcaaaat ccacgagcac atcctgttgt atggcgacat     2340

cagaaagaag cagaaaatta cgatcgccgg ccaagagatg gaggttgaga cactggtggc     2400

tgaagaggag gacgcggccg ccgtgagcaa gggcgaggag ctgttcaccg gggtggtgcc     2460

catcctggtc gagctggacg gcgacgtaaa cggccacaag ttcagcgtgt ccggcgaggg     2520

cgagggcgat gccacctacg gcaagctgac cctgaagttc atctgcacca ccggcaagct     2580

gcccgtgccc tggcccaccc tcgtgaccac cttcggctac ggcctgcagt gcttcgcccg     2640

ctaccccgac cacatgaagc agcacgactt cttcaagtcc gccatgcccg aaggctacgt     2700

ccaggagcgc accatcttct tcaaggacga cggcaactac aagacccgcg ccgaggtgaa     2760

gttcgagggc gacaccctgg tgaaccgcat cgagctgaag ggcatcgact tcaaggagga     2820

cggcaacatc ctggggcaca agctggagta caactacaac agccacaacg tctatatcat     2880

ggccgacaag cagaagaacg gcatcaaggt gaacttcaag atccgccaca acatcgagga     2940

cggcagcgtg cagctcgccg accactacca gcagaacacc cccatcggcg acggccccgt     3000

gctgctgccc gacaaccact acctgagcta ccagtccgcc ctgagcaaag accccaacga     3060

gaagcgcgat cacatggtcc tgctggagtt cgtgaccgcc gccgggatca ctctcggcat     3120

ggacgagctg tacaagtaac atatgctcta gagggcccgc ggttcgaagg taagcctatc     3180

cctaaccctc tcctcggtct cgattctacg cgtaccggtc atcatcacca tcaccattga     3240

gtttaaaccc gctgatcagc ctcgactgtg ccttctagtt gccagccatc tgttgtttgc     3300

ccctcccccg tgccttcctt gaccctggaa ggtgccactc ccactgtcct ttcctaataa     3360

aatgaggaaa ttgcatcgca ttgtctgagt aggtgtcatt ctattctggg gggtggggtg     3420

gggcaggaca gcaaggggga ggattgggaa gacaatagca ggcatgctgg ggatgcggtg     3480

ggctctatgg cttctgaggc ggaaagaacc agctggggct ctagggggta tccccacgcg     3540

ccctgtagcg gcgcattaag cgcggcgggt gtggtggtta cgcgcagcgt gaccgctaca     3600

cttgccagcg ccctagcgcc cgctcctttc gctttcttcc cttcctttct cgccacgttc     3660

gccggctttc cccgtcaagc tctaaatcgg gggctccctt tagggttccg atttagtgct     3720

ttacggcacc tcgaccccaa aaaacttgat tagggtgatg gttcacgtag tgggccatcg     3780

ccctgataga cggtttttcg ccctttgacg ttggagtcca cgttctttaa tagtggactc     3840

ttgttccaaa ctggaacaac actcaaccct atctcggtct attcttttga tttataaggg     3900

attttgggga tttcggccta ttggttaaaa aatgagctga tttaacaaaa atttaacgcg     3960

aattaattct gtggaatgtg tgtcagttag ggtgtggaaa gtccccaggc tccccaggca     4020

ggcagaagta tgcaaagcat gcatctcaat tagtcagcaa ccaggtgtgg aaagtcccca     4080

ggctccccag caggcagaag tatgcaaagc atgcatctca attagtcagc aaccatagtc     4140

ccgcccctaa ctccgcccat cccgccccta actccgccca gttccgccca ttctccgccc     4200

catggctgac taattttttt tatttatgca gaggccgagg ccgcctctgc ctctgagcta     4260

ttccagaagt agtgaggagg cttttttgga ggcctaggct tttgcaaaaa gctcccggga     4320

gcttgtatat ccattttcgg atctgatcaa gagacaggat gaggatcgtt tcgcatgatt     4380

gaacaagatg gattgcacgc aggttctccg gccgcttggg tggagaggct attcggctat     4440

gactgggcac aacagacaat cggctgctct gatgccgccg tgttccggct gtcagcgcag     4500

gggcgcccgg ttctttttgt caagaccgac ctgtccggtg ccctgaatga actgcaggac     4560

gaggcagcgc ggctatcgtg gctggccacg acgggcgttc cttgcgcagc tgtgctcgac     4620

gttgtcactg aagcgggaag ggactggctg ctattgggcg aagtgccggg gcaggatctc     4680

ctgtcatctc accttgctcc tgccgagaaa gtatccatca tggctgatgc aatgcggcgg     4740

ctgcatacgc ttgatccggc tacctgccca ttcgaccacc aagcgaaaca tcgcatcgag     4800

cgagcacgta ctcggatgga agccggtctt gtcgatcagg atgatctgga cgaagagcat     4860

caggggctcg cgccagccga actgttcgcc aggctcaagg cgcgcatgcc cgacggcgag     4920

gatctcgtcg tgacccatgg cgatgcctgc ttgccgaata tcatggtgga aaatggccgc     4980

ttttctggat tcatcgactg tggccggctg ggtgtggcgg accgctatca ggacatagcg     5040

ttggctaccc gtgatattgc tgaagagctt ggcggcgaat gggctgaccg cttcctcgtg     5100

ctttacggta tcgccgctcc cgattcgcag cgcatcgcct tctatcgcct tcttgacgag     5160

ttcttctgag cgggactctg gggttcgcga aatgaccgac caagcgacgc ccaacctgcc     5220

atcacgagat ttcgattcca ccgccgcctt ctatgaaagg ttgggcttcg gaatcgtttt     5280

ccgggacgcc ggctggatga tcctccagcg cggggatctc atgctggagt tcttcgccca     5340

ccccaacttg tttattgcag cttataatgg ttacaaataa agcaatagca tcacaaattt     5400

cacaaataaa gcattttttt cactgcattc tagttgtggt ttgtccaaac tcatcaatgt     5460

atcttatcat gtctgtatac cgtcgacctc tagctagagc ttggcgtaat catggtcata     5520

gctgtttcct gtgtgaaatt gttatccgct cacaattcca cacaacatac gagccggaag     5580

cataaagtgt aaagcctggg gtgcctaatg agtgagctaa ctcacattaa ttgcgttgcg     5640

ctcactgccc gctttccagt cgggaaacct gtcgtgccag ctgcattaat gaatcggcca     5700

acgcgcgggg agaggcggtt tgcgtattgg gcgctcttcc gcttcctcgc tcactgactc     5760

gctgcgctcg gtcgttcggc tgcggcgagc ggtatcagct cactcaaagg cggtaatacg     5820

gttatccaca gaatcagggg ataacgcagg aaagaacatg tgagcaaaag gccagcaaaa     5880

ggccaggaac cgtaaaaagg ccgcgttgct ggcgtttttc cataggctcc gcccccctga     5940

cgagcatcac aaaaatcgac gctcaagtca gaggtggcga aacccgacag gactataaag     6000

ataccaggcg tttccccctg gaagctccct cgtgcgctct cctgttccga ccctgccgct     6060

taccggatac ctgtccgcct ttctcccttc gggaagcgtg gcgctttctc aatgctcacg     6120

ctgtaggtat ctcagttcgg tgtaggtcgt tcgctccaag ctgggctgtg tgcacgaacc     6180

ccccgttcag cccgaccgct gcgccttatc cggtaactat cgtcttgagt ccaacccggt     6240

aagacacgac ttatcgccac tggcagcagc cactggtaac aggattagca gagcgaggta     6300

tgtaggcggt gctacagagt tcttgaagtg gtggcctaac tacggctaca ctagaaggac     6360

agtatttggt atctgcgctc tgctgaagcc agttaccttc ggaaaaagag ttggtagctc     6420

ttgatccggc aaacaaacca ccgctggtag cggtggtttt tttgtttgca agcagcagat     6480

tacgcgcaga aaaaaaggat ctcaagaaga tcctttgatc ttttctacgg ggtctgacgc     6540

tcagtggaac gaaaactcac gttaagggat tttggtcatg agattatcaa aaaggatctt     6600

cacctagatc cttttaaatt aaaaatgaag ttttaaatca atctaaagta tatatgagta     6660

aacttggtct gacagttacc aatgcttaat cagtgaggca cctatctcag cgatctgtct     6720

atttcgttca tccatagttg cctgactccc cgtcgtgtag ataactacga tacgggaggg     6780

cttaccatct ggccccagtg ctgcaatgat accgcgagac ccacgctcac cggctccaga     6840

tttatcagca ataaaccagc cagccggaag ggccgagcgc agaagtggtc ctgcaacttt     6900

atccgcctcc atccagtcta ttaattgttg ccgggaagct agagtaagta gttcgccagt     6960

taatagtttg cgcaacgttg ttgccattgc tacaggcatc gtggtgtcac gctcgtcgtt     7020

tggtatggct tcattcagct ccggttccca acgatcaagg cgagttacat gatcccccat     7080

gttgtgcaaa aaagcggtta gctccttcgg tcctccgatc gttgtcagaa gtaagttggc     7140

cgcagtgtta tcactcatgg ttatggcagc actgcataat tctcttactg tcatgccatc     7200

cgtaagatgc ttttctgtga ctggtgagta ctcaaccaag tcattctgag aatagtgtat     7260

gcggcgaccg agttgctctt gcccggcgtc aatacgggat aataccgcgc cacatagcag     7320

aactttaaaa gtgctcatca ttggaaaacg ttcttcgggg cgaaaactct caaggatctt     7380

accgctgttg agatccagtt cgatgtaacc cactcgtgca cccaactgat cttcagcatc     7440

ttttactttc accagcgttt ctgggtgagc aaaaacagga aggcaaaatg ccgcaaaaaa     7500

gggaataagg gcgacacgga aatgttgaat actcatactc ttcctttttc aatattattg     7560

aagcatttat cagggttatt gtctcatgag cggatacata tttgaatgta tttagaaaaa     7620

taaacaaata ggggttccgc gcacatttcc ccgaaaagtg ccacctgacg tc             7672


<210>  7
<211>  7090
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  7
gacggatcgg gagatctccc gatcccctat ggtcgactct cagtacaatc tgctctgatg       60

ccgcatagtt aagccagtat ctgctccctg cttgtgtgtt ggaggtcgct gagtagtgcg      120

cgagcaaaat ttaagctaca acaaggcaag gcttgaccga caattgcatg aagaatctgc      180

ttagggttag gcgttttgcg ctgcttcgcg atgtacgggc cagatatacg cgttgacatt      240

gattattgac tagttattaa tagtaatcaa ttacggggtc attagttcat agcccatata      300

tggagttccg cgttacataa cttacggtaa atggcccgcc tggctgaccg cccaacgacc      360

cccgcccatt gacgtcaata atgacgtatg ttcccatagt aacgccaata gggactttcc      420

attgacgtca atgggtggag tatttacggt aaactgccca cttggcagta catcaagtgt      480

atcatatgcc aagtacgccc cctattgacg tcaatgacgg taaatggccc gcctggcatt      540

atgcccagta catgacctta tgggactttc ctacttggca gtacatctac gtattagtca      600

tcgctattac catggtgatg cggttttggc agtacatcaa tgggcgtgga tagcggtttg      660

actcacgggg atttccaagt ctccacccca ttgacgtcaa tgggagtttg ttttggcacc      720

aaaatcaacg ggactttcca aaatgtcgta acaactccgc cccattgacg caaatgggcg      780

gtaggcgtgt acggtgggag gtctatataa gcagagctct ctggctaact agagaaccca      840

ctgcttactg gcttatcgaa attaatacga ctcactatag ggagacccaa gctggctagt      900

taagcttggt accgagctcg gatccgccac catggattac cctgttgcta gaagcctcat      960

agttcgctac ccaaccgacc tcggaaacgg caccgtctgc atgccaagag gacagtgtta     1020

ctgtgaaggt tggcttcgga gtcgcggcac ttccattgaa aagacaatag caattactct     1080

tcagtgggta gtctttgctt tgtcagtggc ttgcctgggg tggtatgcgt atcaagcgtg     1140

gcgagctacc tgcggatggg aggaggttta cgtagccttg atagaaatga tgaaaagcat     1200

catcgaggcc ttccacgagt tcgacagccc tgcaacactg tggctgtctt cagggaacgg     1260

cgtagtttgg atgcggtatg gcgaatggct cctcacctgc ccggtccttc tgatccatct     1320

gagcaacctc acaggcctga aggacgatta tagcaaaagg actatgggcc tgttggtttc     1380

tgatgtggga tgcatcgtgt ggggcgcaac cagcgccatg tgtacggggt ggacgaagat     1440

cctgttcttc ctcatctcat tgagctatgg tatgtatacc tattttcatg ctgctaaagt     1500

ttatatcgaa gcattccaca cagttccaaa agggatttgt cgagaactgg tccgagtgat     1560

ggcctggaca ttctttgtgg cttggggaat gtttccagtc ctgtttctgc tgggcacgga     1620

aggattcggt catatcagcc cttatggatc tgccattggg cactccatcc tcgacctgat     1680

tgcaaagaac atgtggggtg tgctggggaa ttacctgcgc gtcaaaatcc acgagcacat     1740

cctgttgtat ggcgacatca gaaagaagca gaaaattacg atcgccggcc aagagatgga     1800

ggttgagaca ctggtggctg aagaggagga cgcggccgcc gtgagcaagg gcgaggagct     1860

gttcaccggg gtggtgccca tcctggtcga gctggacggc gacgtaaacg gccacaagtt     1920

cagcgtgtcc ggcgagggcg agggcgatgc cacctacggc aagctgaccc tgaagttcat     1980

ctgcaccacc ggcaagctgc ccgtgccctg gcccaccctc gtgaccacct tcggctacgg     2040

cctgcagtgc ttcgcccgct accccgacca catgaagcag cacgacttct tcaagtccgc     2100

catgcccgaa ggctacgtcc aggagcgcac catcttcttc aaggacgacg gcaactacaa     2160

gacccgcgcc gaggtgaagt tcgagggcga caccctggtg aaccgcatcg agctgaaggg     2220

catcgacttc aaggaggacg gcaacatcct ggggcacaag ctggagtaca actacaacag     2280

ccacaacgtc tatatcatgg ccgacaagca gaagaacggc atcaaggtga acttcaagat     2340

ccgccacaac atcgaggacg gcagcgtgca gctcgccgac cactaccagc agaacacccc     2400

catcggcgac ggccccgtgc tgctgcccga caaccactac ctgagctacc agtccgccct     2460

gagcaaagac cccaacgaga agcgcgatca catggtcctg ctggagttcg tgaccgccgc     2520

cgggatcact ctcggcatgg acgagctgta caagtaacat atgctctaga gggcccgcgg     2580

ttcgaaggta agcctatccc taaccctctc ctcggtctcg attctacgcg taccggtcat     2640

catcaccatc accattgagt ttaaacccgc tgatcagcct cgactgtgcc ttctagttgc     2700

cagccatctg ttgtttgccc ctcccccgtg ccttccttga ccctggaagg tgccactccc     2760

actgtccttt cctaataaaa tgaggaaatt gcatcgcatt gtctgagtag gtgtcattct     2820

attctggggg gtggggtggg gcaggacagc aagggggagg attgggaaga caatagcagg     2880

catgctgggg atgcggtggg ctctatggct tctgaggcgg aaagaaccag ctggggctct     2940

agggggtatc cccacgcgcc ctgtagcggc gcattaagcg cggcgggtgt ggtggttacg     3000

cgcagcgtga ccgctacact tgccagcgcc ctagcgcccg ctcctttcgc tttcttccct     3060

tcctttctcg ccacgttcgc cggctttccc cgtcaagctc taaatcgggg gctcccttta     3120

gggttccgat ttagtgcttt acggcacctc gaccccaaaa aacttgatta gggtgatggt     3180

tcacgtagtg ggccatcgcc ctgatagacg gtttttcgcc ctttgacgtt ggagtccacg     3240

ttctttaata gtggactctt gttccaaact ggaacaacac tcaaccctat ctcggtctat     3300

tcttttgatt tataagggat tttggggatt tcggcctatt ggttaaaaaa tgagctgatt     3360

taacaaaaat ttaacgcgaa ttaattctgt ggaatgtgtg tcagttaggg tgtggaaagt     3420

ccccaggctc cccaggcagg cagaagtatg caaagcatgc atctcaatta gtcagcaacc     3480

aggtgtggaa agtccccagg ctccccagca ggcagaagta tgcaaagcat gcatctcaat     3540

tagtcagcaa ccatagtccc gcccctaact ccgcccatcc cgcccctaac tccgcccagt     3600

tccgcccatt ctccgcccca tggctgacta atttttttta tttatgcaga ggccgaggcc     3660

gcctctgcct ctgagctatt ccagaagtag tgaggaggct tttttggagg cctaggcttt     3720

tgcaaaaagc tcccgggagc ttgtatatcc attttcggat ctgatcaaga gacaggatga     3780

ggatcgtttc gcatgattga acaagatgga ttgcacgcag gttctccggc cgcttgggtg     3840

gagaggctat tcggctatga ctgggcacaa cagacaatcg gctgctctga tgccgccgtg     3900

ttccggctgt cagcgcaggg gcgcccggtt ctttttgtca agaccgacct gtccggtgcc     3960

ctgaatgaac tgcaggacga ggcagcgcgg ctatcgtggc tggccacgac gggcgttcct     4020

tgcgcagctg tgctcgacgt tgtcactgaa gcgggaaggg actggctgct attgggcgaa     4080

gtgccggggc aggatctcct gtcatctcac cttgctcctg ccgagaaagt atccatcatg     4140

gctgatgcaa tgcggcggct gcatacgctt gatccggcta cctgcccatt cgaccaccaa     4200

gcgaaacatc gcatcgagcg agcacgtact cggatggaag ccggtcttgt cgatcaggat     4260

gatctggacg aagagcatca ggggctcgcg ccagccgaac tgttcgccag gctcaaggcg     4320

cgcatgcccg acggcgagga tctcgtcgtg acccatggcg atgcctgctt gccgaatatc     4380

atggtggaaa atggccgctt ttctggattc atcgactgtg gccggctggg tgtggcggac     4440

cgctatcagg acatagcgtt ggctacccgt gatattgctg aagagcttgg cggcgaatgg     4500

gctgaccgct tcctcgtgct ttacggtatc gccgctcccg attcgcagcg catcgccttc     4560

tatcgccttc ttgacgagtt cttctgagcg ggactctggg gttcgcgaaa tgaccgacca     4620

agcgacgccc aacctgccat cacgagattt cgattccacc gccgccttct atgaaaggtt     4680

gggcttcgga atcgttttcc gggacgccgg ctggatgatc ctccagcgcg gggatctcat     4740

gctggagttc ttcgcccacc ccaacttgtt tattgcagct tataatggtt acaaataaag     4800

caatagcatc acaaatttca caaataaagc atttttttca ctgcattcta gttgtggttt     4860

gtccaaactc atcaatgtat cttatcatgt ctgtataccg tcgacctcta gctagagctt     4920

ggcgtaatca tggtcatagc tgtttcctgt gtgaaattgt tatccgctca caattccaca     4980

caacatacga gccggaagca taaagtgtaa agcctggggt gcctaatgag tgagctaact     5040

cacattaatt gcgttgcgct cactgcccgc tttccagtcg ggaaacctgt cgtgccagct     5100

gcattaatga atcggccaac gcgcggggag aggcggtttg cgtattgggc gctcttccgc     5160

ttcctcgctc actgactcgc tgcgctcggt cgttcggctg cggcgagcgg tatcagctca     5220

ctcaaaggcg gtaatacggt tatccacaga atcaggggat aacgcaggaa agaacatgtg     5280

agcaaaaggc cagcaaaagg ccaggaaccg taaaaaggcc gcgttgctgg cgtttttcca     5340

taggctccgc ccccctgacg agcatcacaa aaatcgacgc tcaagtcaga ggtggcgaaa     5400

cccgacagga ctataaagat accaggcgtt tccccctgga agctccctcg tgcgctctcc     5460

tgttccgacc ctgccgctta ccggatacct gtccgccttt ctcccttcgg gaagcgtggc     5520

gctttctcaa tgctcacgct gtaggtatct cagttcggtg taggtcgttc gctccaagct     5580

gggctgtgtg cacgaacccc ccgttcagcc cgaccgctgc gccttatccg gtaactatcg     5640

tcttgagtcc aacccggtaa gacacgactt atcgccactg gcagcagcca ctggtaacag     5700

gattagcaga gcgaggtatg taggcggtgc tacagagttc ttgaagtggt ggcctaacta     5760

cggctacact agaaggacag tatttggtat ctgcgctctg ctgaagccag ttaccttcgg     5820

aaaaagagtt ggtagctctt gatccggcaa acaaaccacc gctggtagcg gtggtttttt     5880

tgtttgcaag cagcagatta cgcgcagaaa aaaaggatct caagaagatc ctttgatctt     5940

ttctacgggg tctgacgctc agtggaacga aaactcacgt taagggattt tggtcatgag     6000

attatcaaaa aggatcttca cctagatcct tttaaattaa aaatgaagtt ttaaatcaat     6060

ctaaagtata tatgagtaaa cttggtctga cagttaccaa tgcttaatca gtgaggcacc     6120

tatctcagcg atctgtctat ttcgttcatc catagttgcc tgactccccg tcgtgtagat     6180

aactacgata cgggagggct taccatctgg ccccagtgct gcaatgatac cgcgagaccc     6240

acgctcaccg gctccagatt tatcagcaat aaaccagcca gccggaaggg ccgagcgcag     6300

aagtggtcct gcaactttat ccgcctccat ccagtctatt aattgttgcc gggaagctag     6360

agtaagtagt tcgccagtta atagtttgcg caacgttgtt gccattgcta caggcatcgt     6420

ggtgtcacgc tcgtcgtttg gtatggcttc attcagctcc ggttcccaac gatcaaggcg     6480

agttacatga tcccccatgt tgtgcaaaaa agcggttagc tccttcggtc ctccgatcgt     6540

tgtcagaagt aagttggccg cagtgttatc actcatggtt atggcagcac tgcataattc     6600

tcttactgtc atgccatccg taagatgctt ttctgtgact ggtgagtact caaccaagtc     6660

attctgagaa tagtgtatgc ggcgaccgag ttgctcttgc ccggcgtcaa tacgggataa     6720

taccgcgcca catagcagaa ctttaaaagt gctcatcatt ggaaaacgtt cttcggggcg     6780

aaaactctca aggatcttac cgctgttgag atccagttcg atgtaaccca ctcgtgcacc     6840

caactgatct tcagcatctt ttactttcac cagcgtttct gggtgagcaa aaacaggaag     6900

gcaaaatgcc gcaaaaaagg gaataagggc gacacggaaa tgttgaatac tcatactctt     6960

cctttttcaa tattattgaa gcatttatca gggttattgt ctcatgagcg gatacatatt     7020

tgaatgtatt tagaaaaata aacaaatagg ggttccgcgc acatttcccc gaaaagtgcc     7080

acctgacgtc                                                            7090


<210>  8
<211>  758
<212>  DNA
<213>  Gaussia princeps

<400>  8
ggtactcaaa gtatcttctg gcagggaaaa tgggagtgaa agttcttttt gcccttattt       60

gtattgctgt ggccgaggcc aaaccaactg aaaacaatga agatttcaac attgtagctg      120

tagctagcaa ctttgctaca acggatctcg atgctgaccg tggtaaattg cccggaaaaa      180

aattaccact tgaggtactc aaagaaatgg aagccaatgc taggaaagct ggctgcacta      240

ggggatgtct gatatgcctg tcacacatca agtgtacacc caaaatgaag aagtttatcc      300

caggaagatg ccacacctat gaaggagaca aagaaagtgc acagggagga ataggagagg      360

ctattgttga cattcctgaa attcctgggt ttaaggattt ggaacccatg gaacaattca      420

ttgcacaagt tgacctatgt gtagactgca caactggatg cctcaaaggt cttgccaatg      480

tgcaatgttc tgatttactc aagaaatggc tgccacaaag atgtgcaact tttgctagca      540

aaattcaagg ccaagtggac aaaataaagg gtgccggtgg tgattaatcc taatagaata      600

ctgcataact ggatgatgat atactagctt attgctcata aaatggccat tttttgtaac      660

aaatcgagtc tatgtaattc aaaataccta attaattgtt aatacatatg taattcctat      720

aaatataatt tatgcaatcc aaaaaaaaaa aaaaaaaa                              758


<210>  9
<211>  185
<212>  PRT
<213>  Gaussia princeps

<400>  9

Met Gly Val Lys Val Leu Phe Ala Leu Ile Cys Ile Ala Val Ala Glu 
1               5                   10                  15      


Ala Lys Pro Thr Glu Asn Asn Glu Asp Phe Asn Ile Val Ala Val Ala 
            20                  25                  30          


Ser Asn Phe Ala Thr Thr Asp Leu Asp Ala Asp Arg Gly Lys Leu Pro 
        35                  40                  45              


Gly Lys Lys Leu Pro Leu Glu Val Leu Lys Glu Met Glu Ala Asn Ala 
    50                  55                  60                  


Arg Lys Ala Gly Cys Thr Arg Gly Cys Leu Ile Cys Leu Ser His Ile 
65                  70                  75                  80  


Lys Cys Thr Pro Lys Met Lys Lys Phe Ile Pro Gly Arg Cys His Thr 
                85                  90                  95      


Tyr Glu Gly Asp Lys Glu Ser Ala Gln Gly Gly Ile Gly Glu Ala Ile 
            100                 105                 110         


Val Asp Ile Pro Glu Ile Pro Gly Phe Lys Asp Leu Glu Pro Met Glu 
        115                 120                 125             


Gln Phe Ile Ala Gln Val Asp Leu Cys Val Asp Cys Thr Thr Gly Cys 
    130                 135                 140                 


Leu Lys Gly Leu Ala Asn Val Gln Cys Ser Asp Leu Leu Lys Lys Trp 
145                 150                 155                 160 


Leu Pro Gln Arg Cys Ala Thr Phe Ala Ser Lys Ile Gln Gly Gln Val 
                165                 170                 175     


Asp Lys Ile Lys Gly Ala Gly Gly Asp 
            180                 185 


<210>  10
<211>  942
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  10
atggactatg gcggcgcttt gtctgccgtc ggacgcgaac ttttgttcgt tactaatcct       60

gtggtggtga acgggtccgt cctggtccct gaggatcaat gttactgtgc cggatggatt      120

gaatctcgcg gcacgaacgg cgctcagacc gcgtcaaatg tcctgcagtg gcttgcagca      180

ggattcagca ttttgctgct gatgttctat gcctaccaaa cctggaaatc tacatgcggc      240

tgggaggaga tctatgtgtg cgccattgaa atggttaagg tgattctcga gttctttttt      300

gagtttaaga atccctctat gctctacctt gccacaggac accgggtgca gtggctgcgc      360

tatgcagagt ggctgctcac ttgtcctgtc atccttatcc acctgagcaa cctcaccggc      420

ctgagcaacg actacagcag gagaaccatg ggactccttg tctcagacat cgggactatc      480

gtgtgggggg ctaccagcgc catggcaacc ggctatgtta aagtcatctt cttttgtctt      540

ggattgtgct atggcgcgaa cacatttttt cacgccgcca aagcatatat cgagggttat      600

catactgtgc caaagggtcg gtgccgccag gtcgtgaccg gcatggcatg gctgtttttc      660

gtgagctggg gtatgttccc aattctcttc attttggggc ccgaaggttt tggcgtcctg      720

agcgtctatg gctccaccgt aggtcacacg attattgatc tgatgagtaa aaattgttgg      780

gggttgttgg gacactacct gcgcgtcctg atccacgagc acatattgat tcacggagat      840

atccgcaaaa ccaccaaact gaacatcggc ggaacggaga tcgaggtcga gactctcgtc      900

gaagacgaag ccgaggccgg agccgtgcca gcggccgcca cc                         942


<210>  11
<211>  314
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  11

Met Asp Tyr Gly Gly Ala Leu Ser Ala Val Gly Arg Glu Leu Leu Phe 
1               5                   10                  15      


Val Thr Asn Pro Val Val Val Asn Gly Ser Val Leu Val Pro Glu Asp 
            20                  25                  30          


Gln Cys Tyr Cys Ala Gly Trp Ile Glu Ser Arg Gly Thr Asn Gly Ala 
        35                  40                  45              


Gln Thr Ala Ser Asn Val Leu Gln Trp Leu Ala Ala Gly Phe Ser Ile 
    50                  55                  60                  


Leu Leu Leu Met Phe Tyr Ala Tyr Gln Thr Trp Lys Ser Thr Cys Gly 
65                  70                  75                  80  


Trp Glu Glu Ile Tyr Val Cys Ala Ile Glu Met Val Lys Val Ile Leu 
                85                  90                  95      


Glu Phe Phe Phe Glu Phe Lys Asn Pro Ser Met Leu Tyr Leu Ala Thr 
            100                 105                 110         


Gly His Arg Val Gln Trp Leu Arg Tyr Ala Glu Trp Leu Leu Thr Cys 
        115                 120                 125             


Pro Val Ile Leu Ile His Leu Ser Asn Leu Thr Gly Leu Ser Asn Asp 
    130                 135                 140                 


Tyr Ser Arg Arg Thr Met Gly Leu Leu Val Ser Asp Ile Gly Thr Ile 
145                 150                 155                 160 


Val Trp Gly Ala Thr Ser Ala Met Ala Thr Gly Tyr Val Lys Val Ile 
                165                 170                 175     


Phe Phe Cys Leu Gly Leu Cys Tyr Gly Ala Asn Thr Phe Phe His Ala 
            180                 185                 190         


Ala Lys Ala Tyr Ile Glu Gly Tyr His Thr Val Pro Lys Gly Arg Cys 
        195                 200                 205             


Arg Gln Val Val Thr Gly Met Ala Trp Leu Phe Phe Val Ser Trp Gly 
    210                 215                 220                 


Met Phe Pro Ile Leu Phe Ile Leu Gly Pro Glu Gly Phe Gly Val Leu 
225                 230                 235                 240 


Ser Val Tyr Gly Ser Thr Val Gly His Thr Ile Ile Asp Leu Met Ser 
                245                 250                 255     


Lys Asn Cys Trp Gly Leu Leu Gly His Tyr Leu Arg Val Leu Ile His 
            260                 265                 270         


Glu His Ile Leu Ile His Gly Asp Ile Arg Lys Thr Thr Lys Leu Asn 
        275                 280                 285             


Ile Gly Gly Thr Glu Ile Glu Val Glu Thr Leu Val Glu Asp Glu Ala 
    290                 295                 300                 


Glu Ala Gly Ala Val Pro Ala Ala Ala Thr 
305                 310                 


<210>  12
<211>  909
<212>  DNA
<213>  Volvox carteri

<400>  12
atggattacc ctgttgctag aagcctcata gttcgctacc caaccgacct cggaaacggc       60

accgtctgca tgccaagagg acagtgttac tgtgaaggtt ggcttcggag tcgcggcact      120

tccattgaaa agacaatagc aattactctt cagtgggtag tctttgcttt gtcagtggct      180

tgcctggggt ggtatgcgta tcaagcgtgg cgagctacct gcggatggga ggaggtttac      240

gtagccttga tagaaatgat gaaaagcatc atcgaggcct tccacgagtt cgacagccct      300

gcaacactgt ggctgtcttc agggaacggc gtagtttgga tgcggtatgg cgaatggctc      360

ctcacctgcc cggtccttct gatccatctg agcaacctca caggcctgaa ggacgattat      420

agcaaaagga ctatgggcct gttggtttct gatgtgggat gcatcgtgtg gggcgcaacc      480

agcgccatgt gtacggggtg gacgaagatc ctgttcttcc tcatctcatt gagctatggt      540

atgtatacct attttcatgc tgctaaagtt tatatcgaag cattccacac agttccaaaa      600

gggatttgtc gagaactggt ccgagtgatg gcctggacat tctttgtggc ttggggaatg      660

tttccagtcc tgtttctgct gggcacggaa ggattcggtc atatcagccc ttatggatct      720

gccattgggc actccatcct cgacctgatt gcaaagaaca tgtggggtgt gctggggaat      780

tacctgcgcg tcaaaatcca cgagcacatc ctgttgtatg gcgacatcag aaagaagcag      840

aaaattacga tcgccggcca agagatggag gttgagacac tggtggctga agaggaggac      900

gcggccgcc                                                              909


<210>  13
<211>  303
<212>  PRT
<213>  Volvox carteri

<400>  13

Met Asp Tyr Pro Val Ala Arg Ser Leu Ile Val Arg Tyr Pro Thr Asp 
1               5                   10                  15      


Leu Gly Asn Gly Thr Val Cys Met Pro Arg Gly Gln Cys Tyr Cys Glu 
            20                  25                  30          


Gly Trp Leu Arg Ser Arg Gly Thr Ser Ile Glu Lys Thr Ile Ala Ile 
        35                  40                  45              


Thr Leu Gln Trp Val Val Phe Ala Leu Ser Val Ala Cys Leu Gly Trp 
    50                  55                  60                  


Tyr Ala Tyr Gln Ala Trp Arg Ala Thr Cys Gly Trp Glu Glu Val Tyr 
65                  70                  75                  80  


Val Ala Leu Ile Glu Met Met Lys Ser Ile Ile Glu Ala Phe His Glu 
                85                  90                  95      


Phe Asp Ser Pro Ala Thr Leu Trp Leu Ser Ser Gly Asn Gly Val Val 
            100                 105                 110         


Trp Met Arg Tyr Gly Glu Trp Leu Leu Thr Cys Pro Val Leu Leu Ile 
        115                 120                 125             


His Leu Ser Asn Leu Thr Gly Leu Lys Asp Asp Tyr Ser Lys Arg Thr 
    130                 135                 140                 


Met Gly Leu Leu Val Ser Asp Val Gly Cys Ile Val Trp Gly Ala Thr 
145                 150                 155                 160 


Ser Ala Met Cys Thr Gly Trp Thr Lys Ile Leu Phe Phe Leu Ile Ser 
                165                 170                 175     


Leu Ser Tyr Gly Met Tyr Thr Tyr Phe His Ala Ala Lys Val Tyr Ile 
            180                 185                 190         


Glu Ala Phe His Thr Val Pro Lys Gly Ile Cys Arg Glu Leu Val Arg 
        195                 200                 205             


Val Met Ala Trp Thr Phe Phe Val Ala Trp Gly Met Phe Pro Val Leu 
    210                 215                 220                 


Phe Leu Leu Gly Thr Glu Gly Phe Gly His Ile Ser Pro Tyr Gly Ser 
225                 230                 235                 240 


Ala Ile Gly His Ser Ile Leu Asp Leu Ile Ala Lys Asn Met Trp Gly 
                245                 250                 255     


Val Leu Gly Asn Tyr Leu Arg Val Lys Ile His Glu His Ile Leu Leu 
            260                 265                 270         


Tyr Gly Asp Ile Arg Lys Lys Gln Lys Ile Thr Ile Ala Gly Gln Glu 
        275                 280                 285             


Met Glu Val Glu Thr Leu Val Ala Glu Glu Glu Asp Ala Ala Ala 
    290                 295                 300             


<210>  14
<211>  873
<212>  DNA
<213>  Natronomonas

<400>  14
atgacagaga ccctgcctcc cgtgaccgag agtgccgtgg cccttcaagc cgaggttacc       60

caaagggagt tgttcgagtt cgtgctgaac gaccctttgc ttgcaagcag tctctatatc      120

aacatcgcac ttgcaggact gagtatactg ctgttcgttt ttatgacccg aggactcgat      180

gatccacggg caaaacttat tgctgtgtca accatccttg tgcctgtcgt cagcattgcc      240

tcctacactg gattggcgag cggcctgaca atttccgttc ttgaaatgcc agcgggccat      300

tttgcagaag gcagctcagt gatgctggga ggagaagagg tagatggtgt agtcaccatg      360

tggggacggt atctcacctg ggcactttcc acgcccatga ttctcctcgc tctgggtctc      420

ctggccggaa gcaatgctac aaagctcttc acagctatca ctttcgatat cgctatgtgc      480

gtgactggcc ttgccgcggc cctgactacc tcctcccacc tcatgagatg gttctggtac      540

gctatcagtt gtgcatgctt tctggtggtc ttgtatatcc tgctggtgga gtgggcacag      600

gacgccaaag ccgcgggaac cgctgacatg ttcaataccc tgaagctgtt gacagtagtg      660

atgtggctgg ggtatccaat tgtgtgggct cttggagtcg agggtatcgc ggtgttgccc      720

gttggggtga cgagctgggg atattctttc ctggatatcg tggcaaagta cattttcgca      780

ttcttgctcc tgaactatct gacgtcaaac gaatctgtcg tgtccggcag cattttggat      840

gttccatctg cttctgggac cccggctgat gat                                   873


<210>  15
<211>  291
<212>  PRT
<213>  Natronomonas

<400>  15

Met Thr Glu Thr Leu Pro Pro Val Thr Glu Ser Ala Val Ala Leu Gln 
1               5                   10                  15      


Ala Glu Val Thr Gln Arg Glu Leu Phe Glu Phe Val Leu Asn Asp Pro 
            20                  25                  30          


Leu Leu Ala Ser Ser Leu Tyr Ile Asn Ile Ala Leu Ala Gly Leu Ser 
        35                  40                  45              


Ile Leu Leu Phe Val Phe Met Thr Arg Gly Leu Asp Asp Pro Arg Ala 
    50                  55                  60                  


Lys Leu Ile Ala Val Ser Thr Ile Leu Val Pro Val Val Ser Ile Ala 
65                  70                  75                  80  


Ser Tyr Thr Gly Leu Ala Ser Gly Leu Thr Ile Ser Val Leu Glu Met 
                85                  90                  95      


Pro Ala Gly His Phe Ala Glu Gly Ser Ser Val Met Leu Gly Gly Glu 
            100                 105                 110         


Glu Val Asp Gly Val Val Thr Met Trp Gly Arg Tyr Leu Thr Trp Ala 
        115                 120                 125             


Leu Ser Thr Pro Met Ile Leu Leu Ala Leu Gly Leu Leu Ala Gly Ser 
    130                 135                 140                 


Asn Ala Thr Lys Leu Phe Thr Ala Ile Thr Phe Asp Ile Ala Met Cys 
145                 150                 155                 160 


Val Thr Gly Leu Ala Ala Ala Leu Thr Thr Ser Ser His Leu Met Arg 
                165                 170                 175     


Trp Phe Trp Tyr Ala Ile Ser Cys Ala Cys Phe Leu Val Val Leu Tyr 
            180                 185                 190         


Ile Leu Leu Val Glu Trp Ala Gln Asp Ala Lys Ala Ala Gly Thr Ala 
        195                 200                 205             


Asp Met Phe Asn Thr Leu Lys Leu Leu Thr Val Val Met Trp Leu Gly 
    210                 215                 220                 


Tyr Pro Ile Val Trp Ala Leu Gly Val Glu Gly Ile Ala Val Leu Pro 
225                 230                 235                 240 


Val Gly Val Thr Ser Trp Gly Tyr Ser Phe Leu Asp Ile Val Ala Lys 
                245                 250                 255     


Tyr Ile Phe Ala Phe Leu Leu Leu Asn Tyr Leu Thr Ser Asn Glu Ser 
            260                 265                 270         


Val Val Ser Gly Ser Ile Leu Asp Val Pro Ser Ala Ser Gly Thr Pro 
        275                 280                 285             


Ala Asp Asp 
    290     


<210>  16
<211>  600
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  16
atgggagtca aagttctgtt tgccctgatc tgcatcgctg tggccgaggc caagcccacc       60

gagaacaacg aagacttcaa catcgtggcc gtggccagca acttcgcgac cacggatctc      120

gatgctgacc gcgggaagtt gcccggcaag aagctgccgc tggaggtgct caaagagatg      180

gaagccaatg cccggaaagc tggctgcacc aggggctgtc tgatctgcct gtcccacatc      240

aagtgcacgc ccaagatgaa gaagttcatc ccaggacgct gccacaccta cgaaggcgac      300

aaagagtccg cacagggcgg cataggcgag gcgatcgtcg acattcctga gattcctggg      360

ttcaaggact tggagcccat ggagcagttc atcgcacagg tcgatctgtg tgtggactgc      420

acaactggct gcctcaaagg gcttgccaac gtgcagtgtt ctgacctgct caagaagtgg      480

ctgccgcaac gctgtgcgac ctttgccagc aagatccagg gccaggtgga caagatcaag      540

ggggccggtg gtgacgggga tccactagtc cagtgtggtg gaattgccct tgctgccacc      600


<210>  17
<211>  2262
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  17
atgggagtca aagttctgtt tgccctgatc tgcatcgctg tggccgaggc caagcccacc       60

gagaacaacg aagacttcaa catcgtggcc gtggccagca acttcgcgac cacggatctc      120

gatgctgacc gcgggaagtt gcccggcaag aagctgccgc tggaggtgct caaagagatg      180

gaagccaatg cccggaaagc tggctgcacc aggggctgtc tgatctgcct gtcccacatc      240

aagtgcacgc ccaagatgaa gaagttcatc ccaggacgct gccacaccta cgaaggcgac      300

aaagagtccg cacagggcgg cataggcgag gcgatcgtcg acattcctga gattcctggg      360

ttcaaggact tggagcccat ggagcagttc atcgcacagg tcgatctgtg tgtggactgc      420

acaactggct gcctcaaagg gcttgccaac gtgcagtgtt ctgacctgct caagaagtgg      480

ctgccgcaac gctgtgcgac ctttgccagc aagatccagg gccaggtgga caagatcaag      540

ggggccggtg gtgacgggga tccactagtc cagtgtggtg gaattgccct tgctgccacc      600

atggactatg gcggcgcttt gtctgccgtc ggacgcgaac ttttgttcgt tactaatcct      660

gtggtggtga acgggtccgt cctggtccct gaggatcaat gttactgtgc cggatggatt      720

gaatctcgcg gcacgaacgg cgctcagacc gcgtcaaatg tcctgcagtg gcttgcagca      780

ggattcagca ttttgctgct gatgttctat gcctaccaaa cctggaaatc tacatgcggc      840

tgggaggaga tctatgtgtg cgccattgaa atggttaagg tgattctcga gttctttttt      900

gagtttaaga atccctctat gctctacctt gccacaggac accgggtgca gtggctgcgc      960

tatgcagagt ggctgctcac ttgtcctgtc atccttatcc acctgagcaa cctcaccggc     1020

ctgagcaacg actacagcag gagaaccatg ggactccttg tctcagacat cgggactatc     1080

gtgtgggggg ctaccagcgc catggcaacc ggctatgtta aagtcatctt cttttgtctt     1140

ggattgtgct atggcgcgaa cacatttttt cacgccgcca aagcatatat cgagggttat     1200

catactgtgc caaagggtcg gtgccgccag gtcgtgaccg gcatggcatg gctgtttttc     1260

gtgagctggg gtatgttccc aattctcttc attttggggc ccgaaggttt tggcgtcctg     1320

agcgtctatg gctccaccgt aggtcacacg attattgatc tgatgagtaa aaattgttgg     1380

gggttgttgg gacactacct gcgcgtcctg atccacgagc acatattgat tcacggagat     1440

atccgcaaaa ccaccaaact gaacatcggc ggaacggaga tcgaggtcga gactctcgtc     1500

gaagacgaag ccgaggccgg agccgtgcca gcggccgcca ccatggtgag caagggcgag     1560

gagctgttca ccggggtggt gcccatcctg gtcgagctgg acggcgacgt aaacggccac     1620

aagttcagcg tgtccggcga gggcgagggc gatgccacct acggcaagct gaccctgaag     1680

ttcatctgca ccaccggcaa gctgcccgtg ccctggccca ccctcgtgac caccttcggc     1740

tacggcctgc agtgcttcgc ccgctacccc gaccacatga agcagcacga cttcttcaag     1800

tccgccatgc ccgaaggcta cgtccaggag cgcaccatct tcttcaagga cgacggcaac     1860

tacaagaccc gcgccgaggt gaagttcgag ggcgacaccc tggtgaaccg catcgagctg     1920

aagggcatcg acttcaagga ggacggcaac atcctggggc acaagctgga gtacaactac     1980

aacagccaca acgtctatat catggccgac aagcagaaga acggcatcaa ggtgaacttc     2040

aagatccgcc acaacatcga ggacggcagc gtgcagctcg ccgaccacta ccagcagaac     2100

acccccatcg gcgacggccc cgtgctgctg cccgacaacc actacctgag ctaccagtcc     2160

gccctgagca aagaccccaa cgagaagcgc gatcacatgg tcctgctgga gttcgtgacc     2220

gccgccggga tcactctcgg catggacgag ctgtacaagt aa                        2262


<210>  18
<211>  753
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  18

Met Gly Val Lys Val Leu Phe Ala Leu Ile Cys Ile Ala Val Ala Glu 
1               5                   10                  15      


Ala Lys Pro Thr Glu Asn Asn Glu Asp Phe Asn Ile Val Ala Val Ala 
            20                  25                  30          


Ser Asn Phe Ala Thr Thr Asp Leu Asp Ala Asp Arg Gly Lys Leu Pro 
        35                  40                  45              


Gly Lys Lys Leu Pro Leu Glu Val Leu Lys Glu Met Glu Ala Asn Ala 
    50                  55                  60                  


Arg Lys Ala Gly Cys Thr Arg Gly Cys Leu Ile Cys Leu Ser His Ile 
65                  70                  75                  80  


Lys Cys Thr Pro Lys Met Lys Lys Phe Ile Pro Gly Arg Cys His Thr 
                85                  90                  95      


Tyr Glu Gly Asp Lys Glu Ser Ala Gln Gly Gly Ile Gly Glu Ala Ile 
            100                 105                 110         


Val Asp Ile Pro Glu Ile Pro Gly Phe Lys Asp Leu Glu Pro Met Glu 
        115                 120                 125             


Gln Phe Ile Ala Gln Val Asp Leu Cys Val Asp Cys Thr Thr Gly Cys 
    130                 135                 140                 


Leu Lys Gly Leu Ala Asn Val Gln Cys Ser Asp Leu Leu Lys Lys Trp 
145                 150                 155                 160 


Leu Pro Gln Arg Cys Ala Thr Phe Ala Ser Lys Ile Gln Gly Gln Val 
                165                 170                 175     


Asp Lys Ile Lys Gly Ala Gly Gly Asp Gly Asp Pro Leu Val Gln Cys 
            180                 185                 190         


Gly Gly Ile Ala Leu Ala Ala Thr Met Asp Tyr Gly Gly Ala Leu Ser 
        195                 200                 205             


Ala Val Gly Arg Glu Leu Leu Phe Val Thr Asn Pro Val Val Val Asn 
    210                 215                 220                 


Gly Ser Val Leu Val Pro Glu Asp Gln Cys Tyr Cys Ala Gly Trp Ile 
225                 230                 235                 240 


Glu Ser Arg Gly Thr Asn Gly Ala Gln Thr Ala Ser Asn Val Leu Gln 
                245                 250                 255     


Trp Leu Ala Ala Gly Phe Ser Ile Leu Leu Leu Met Phe Tyr Ala Tyr 
            260                 265                 270         


Gln Thr Trp Lys Ser Thr Cys Gly Trp Glu Glu Ile Tyr Val Cys Ala 
        275                 280                 285             


Ile Glu Met Val Lys Val Ile Leu Glu Phe Phe Phe Glu Phe Lys Asn 
    290                 295                 300                 


Pro Ser Met Leu Tyr Leu Ala Thr Gly His Arg Val Gln Trp Leu Arg 
305                 310                 315                 320 


Tyr Ala Glu Trp Leu Leu Thr Cys Pro Val Ile Leu Ile His Leu Ser 
                325                 330                 335     


Asn Leu Thr Gly Leu Ser Asn Asp Tyr Ser Arg Arg Thr Met Gly Leu 
            340                 345                 350         


Leu Val Ser Asp Ile Gly Thr Ile Val Trp Gly Ala Thr Ser Ala Met 
        355                 360                 365             


Ala Thr Gly Tyr Val Lys Val Ile Phe Phe Cys Leu Gly Leu Cys Tyr 
    370                 375                 380                 


Gly Ala Asn Thr Phe Phe His Ala Ala Lys Ala Tyr Ile Glu Gly Tyr 
385                 390                 395                 400 


His Thr Val Pro Lys Gly Arg Cys Arg Gln Val Val Thr Gly Met Ala 
                405                 410                 415     


Trp Leu Phe Phe Val Ser Trp Gly Met Phe Pro Ile Leu Phe Ile Leu 
            420                 425                 430         


Gly Pro Glu Gly Phe Gly Val Leu Ser Val Tyr Gly Ser Thr Val Gly 
        435                 440                 445             


His Thr Ile Ile Asp Leu Met Ser Lys Asn Cys Trp Gly Leu Leu Gly 
    450                 455                 460                 


His Tyr Leu Arg Val Leu Ile His Glu His Ile Leu Ile His Gly Asp 
465                 470                 475                 480 


Ile Arg Lys Thr Thr Lys Leu Asn Ile Gly Gly Thr Glu Ile Glu Val 
                485                 490                 495     


Glu Thr Leu Val Glu Asp Glu Ala Glu Ala Gly Ala Val Pro Ala Ala 
            500                 505                 510         


Ala Thr Met Val Ser Lys Gly Glu Glu Leu Phe Thr Gly Val Val Pro 
        515                 520                 525             


Ile Leu Val Glu Leu Asp Gly Asp Val Asn Gly His Lys Phe Ser Val 
    530                 535                 540                 


Ser Gly Glu Gly Glu Gly Asp Ala Thr Tyr Gly Lys Leu Thr Leu Lys 
545                 550                 555                 560 


Phe Ile Cys Thr Thr Gly Lys Leu Pro Val Pro Trp Pro Thr Leu Val 
                565                 570                 575     


Thr Thr Phe Gly Tyr Gly Leu Gln Cys Phe Ala Arg Tyr Pro Asp His 
            580                 585                 590         


Met Lys Gln His Asp Phe Phe Lys Ser Ala Met Pro Glu Gly Tyr Val 
        595                 600                 605             


Gln Glu Arg Thr Ile Phe Phe Lys Asp Asp Gly Asn Tyr Lys Thr Arg 
    610                 615                 620                 


Ala Glu Val Lys Phe Glu Gly Asp Thr Leu Val Asn Arg Ile Glu Leu 
625                 630                 635                 640 


Lys Gly Ile Asp Phe Lys Glu Asp Gly Asn Ile Leu Gly His Lys Leu 
                645                 650                 655     


Glu Tyr Asn Tyr Asn Ser His Asn Val Tyr Ile Met Ala Asp Lys Gln 
            660                 665                 670         


Lys Asn Gly Ile Lys Val Asn Phe Lys Ile Arg His Asn Ile Glu Asp 
        675                 680                 685             


Gly Ser Val Gln Leu Ala Asp His Tyr Gln Gln Asn Thr Pro Ile Gly 
    690                 695                 700                 


Asp Gly Pro Val Leu Leu Pro Asp Asn His Tyr Leu Ser Tyr Gln Ser 
705                 710                 715                 720 


Ala Leu Ser Lys Asp Pro Asn Glu Lys Arg Asp His Met Val Leu Leu 
                725                 730                 735     


Glu Phe Val Thr Ala Ala Gly Ile Thr Leu Gly Met Asp Glu Leu Tyr 
            740                 745                 750         


Lys 
    


<210>  19
<211>  2226
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  19
atgggagtca aagttctgtt tgccctgatc tgcatcgctg tggccgaggc caagcccacc       60

gagaacaacg aagacttcaa catcgtggcc gtggccagca acttcgcgac cacggatctc      120

gatgctgacc gcgggaagtt gcccggcaag aagctgccgc tggaggtgct caaagagatg      180

gaagccaatg cccggaaagc tggctgcacc aggggctgtc tgatctgcct gtcccacatc      240

aagtgcacgc ccaagatgaa gaagttcatc ccaggacgct gccacaccta cgaaggcgac      300

aaagagtccg cacagggcgg cataggcgag gcgatcgtcg acattcctga gattcctggg      360

ttcaaggact tggagcccat ggagcagttc atcgcacagg tcgatctgtg tgtggactgc      420

acaactggct gcctcaaagg gcttgccaac gtgcagtgtt ctgacctgct caagaagtgg      480

ctgccgcaac gctgtgcgac ctttgccagc aagatccagg gccaggtgga caagatcaag      540

ggggccggtg gtgacggcga cccactagtc cagtgtggtg gaattgccgg atccgccacc      600

atggattacc ctgttgctag aagcctcata gttcgctacc caaccgacct cggaaacggc      660

accgtctgca tgccaagagg acagtgttac tgtgaaggtt ggcttcggag tcgcggcact      720

tccattgaaa agacaatagc aattactctt cagtgggtag tctttgcttt gtcagtggct      780

tgcctggggt ggtatgcgta tcaagcgtgg cgagctacct gcggatggga ggaggtttac      840

gtagccttga tagaaatgat gaaaagcatc atcgaggcct tccacgagtt cgacagccct      900

gcaacactgt ggctgtcttc agggaacggc gtagtttgga tgcggtatgg cgaatggctc      960

ctcacctgcc cggtccttct gatccatctg agcaacctca caggcctgaa ggacgattat     1020

agcaaaagga ctatgggcct gttggtttct gatgtgggat gcatcgtgtg gggcgcaacc     1080

agcgccatgt gtacggggtg gacgaagatc ctgttcttcc tcatctcatt gagctatggt     1140

atgtatacct attttcatgc tgctaaagtt tatatcgaag cattccacac agttccaaaa     1200

gggatttgtc gagaactggt ccgagtgatg gcctggacat tctttgtggc ttggggaatg     1260

tttccagtcc tgtttctgct gggcacggaa ggattcggtc atatcagccc ttatggatct     1320

gccattgggc actccatcct cgacctgatt gcaaagaaca tgtggggtgt gctggggaat     1380

tacctgcgcg tcaaaatcca cgagcacatc ctgttgtatg gcgacatcag aaagaagcag     1440

aaaattacga tcgccggcca agagatggag gttgagacac tggtggctga agaggaggac     1500

gcggccgccg tgagcaaggg cgaggagctg ttcaccgggg tggtgcccat cctggtcgag     1560

ctggacggcg acgtaaacgg ccacaagttc agcgtgtccg gcgagggcga gggcgatgcc     1620

acctacggca agctgaccct gaagttcatc tgcaccaccg gcaagctgcc cgtgccctgg     1680

cccaccctcg tgaccacctt cggctacggc ctgcagtgct tcgcccgcta ccccgaccac     1740

atgaagcagc acgacttctt caagtccgcc atgcccgaag gctacgtcca ggagcgcacc     1800

atcttcttca aggacgacgg caactacaag acccgcgccg aggtgaagtt cgagggcgac     1860

accctggtga accgcatcga gctgaagggc atcgacttca aggaggacgg caacatcctg     1920

gggcacaagc tggagtacaa ctacaacagc cacaacgtct atatcatggc cgacaagcag     1980

aagaacggca tcaaggtgaa cttcaagatc cgccacaaca tcgaggacgg cagcgtgcag     2040

ctcgccgacc actaccagca gaacaccccc atcggcgacg gccccgtgct gctgcccgac     2100

aaccactacc tgagctacca gtccgccctg agcaaagacc ccaacgagaa gcgcgatcac     2160

atggtcctgc tggagttcgt gaccgccgcc gggatcactc tcggcatgga cgagctgtac     2220

aagtaa                                                                2226


<210>  20
<211>  741
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  20

Met Gly Val Lys Val Leu Phe Ala Leu Ile Cys Ile Ala Val Ala Glu 
1               5                   10                  15      


Ala Lys Pro Thr Glu Asn Asn Glu Asp Phe Asn Ile Val Ala Val Ala 
            20                  25                  30          


Ser Asn Phe Ala Thr Thr Asp Leu Asp Ala Asp Arg Gly Lys Leu Pro 
        35                  40                  45              


Gly Lys Lys Leu Pro Leu Glu Val Leu Lys Glu Met Glu Ala Asn Ala 
    50                  55                  60                  


Arg Lys Ala Gly Cys Thr Arg Gly Cys Leu Ile Cys Leu Ser His Ile 
65                  70                  75                  80  


Lys Cys Thr Pro Lys Met Lys Lys Phe Ile Pro Gly Arg Cys His Thr 
                85                  90                  95      


Tyr Glu Gly Asp Lys Glu Ser Ala Gln Gly Gly Ile Gly Glu Ala Ile 
            100                 105                 110         


Val Asp Ile Pro Glu Ile Pro Gly Phe Lys Asp Leu Glu Pro Met Glu 
        115                 120                 125             


Gln Phe Ile Ala Gln Val Asp Leu Cys Val Asp Cys Thr Thr Gly Cys 
    130                 135                 140                 


Leu Lys Gly Leu Ala Asn Val Gln Cys Ser Asp Leu Leu Lys Lys Trp 
145                 150                 155                 160 


Leu Pro Gln Arg Cys Ala Thr Phe Ala Ser Lys Ile Gln Gly Gln Val 
                165                 170                 175     


Asp Lys Ile Lys Gly Ala Gly Gly Asp Gly Asp Pro Leu Val Gln Cys 
            180                 185                 190         


Gly Gly Ile Ala Gly Ser Ala Thr Met Asp Tyr Pro Val Ala Arg Ser 
        195                 200                 205             


Leu Ile Val Arg Tyr Pro Thr Asp Leu Gly Asn Gly Thr Val Cys Met 
    210                 215                 220                 


Pro Arg Gly Gln Cys Tyr Cys Glu Gly Trp Leu Arg Ser Arg Gly Thr 
225                 230                 235                 240 


Ser Ile Glu Lys Thr Ile Ala Ile Thr Leu Gln Trp Val Val Phe Ala 
                245                 250                 255     


Leu Ser Val Ala Cys Leu Gly Trp Tyr Ala Tyr Gln Ala Trp Arg Ala 
            260                 265                 270         


Thr Cys Gly Trp Glu Glu Val Tyr Val Ala Leu Ile Glu Met Met Lys 
        275                 280                 285             


Ser Ile Ile Glu Ala Phe His Glu Phe Asp Ser Pro Ala Thr Leu Trp 
    290                 295                 300                 


Leu Ser Ser Gly Asn Gly Val Val Trp Met Arg Tyr Gly Glu Trp Leu 
305                 310                 315                 320 


Leu Thr Cys Pro Val Leu Leu Ile His Leu Ser Asn Leu Thr Gly Leu 
                325                 330                 335     


Lys Asp Asp Tyr Ser Lys Arg Thr Met Gly Leu Leu Val Ser Asp Val 
            340                 345                 350         


Gly Cys Ile Val Trp Gly Ala Thr Ser Ala Met Cys Thr Gly Trp Thr 
        355                 360                 365             


Lys Ile Leu Phe Phe Leu Ile Ser Leu Ser Tyr Gly Met Tyr Thr Tyr 
    370                 375                 380                 


Phe His Ala Ala Lys Val Tyr Ile Glu Ala Phe His Thr Val Pro Lys 
385                 390                 395                 400 


Gly Ile Cys Arg Glu Leu Val Arg Val Met Ala Trp Thr Phe Phe Val 
                405                 410                 415     


Ala Trp Gly Met Phe Pro Val Leu Phe Leu Leu Gly Thr Glu Gly Phe 
            420                 425                 430         


Gly His Ile Ser Pro Tyr Gly Ser Ala Ile Gly His Ser Ile Leu Asp 
        435                 440                 445             


Leu Ile Ala Lys Asn Met Trp Gly Val Leu Gly Asn Tyr Leu Arg Val 
    450                 455                 460                 


Lys Ile His Glu His Ile Leu Leu Tyr Gly Asp Ile Arg Lys Lys Gln 
465                 470                 475                 480 


Lys Ile Thr Ile Ala Gly Gln Glu Met Glu Val Glu Thr Leu Val Ala 
                485                 490                 495     


Glu Glu Glu Asp Ala Ala Ala Val Ser Lys Gly Glu Glu Leu Phe Thr 
            500                 505                 510         


Gly Val Val Pro Ile Leu Val Glu Leu Asp Gly Asp Val Asn Gly His 
        515                 520                 525             


Lys Phe Ser Val Ser Gly Glu Gly Glu Gly Asp Ala Thr Tyr Gly Lys 
    530                 535                 540                 


Leu Thr Leu Lys Phe Ile Cys Thr Thr Gly Lys Leu Pro Val Pro Trp 
545                 550                 555                 560 


Pro Thr Leu Val Thr Thr Phe Gly Tyr Gly Leu Gln Cys Phe Ala Arg 
                565                 570                 575     


Tyr Pro Asp His Met Lys Gln His Asp Phe Phe Lys Ser Ala Met Pro 
            580                 585                 590         


Glu Gly Tyr Val Gln Glu Arg Thr Ile Phe Phe Lys Asp Asp Gly Asn 
        595                 600                 605             


Tyr Lys Thr Arg Ala Glu Val Lys Phe Glu Gly Asp Thr Leu Val Asn 
    610                 615                 620                 


Arg Ile Glu Leu Lys Gly Ile Asp Phe Lys Glu Asp Gly Asn Ile Leu 
625                 630                 635                 640 


Gly His Lys Leu Glu Tyr Asn Tyr Asn Ser His Asn Val Tyr Ile Met 
                645                 650                 655     


Ala Asp Lys Gln Lys Asn Gly Ile Lys Val Asn Phe Lys Ile Arg His 
            660                 665                 670         


Asn Ile Glu Asp Gly Ser Val Gln Leu Ala Asp His Tyr Gln Gln Asn 
        675                 680                 685             


Thr Pro Ile Gly Asp Gly Pro Val Leu Leu Pro Asp Asn His Tyr Leu 
    690                 695                 700                 


Ser Tyr Gln Ser Ala Leu Ser Lys Asp Pro Asn Glu Lys Arg Asp His 
705                 710                 715                 720 


Met Val Leu Leu Glu Phe Val Thr Ala Ala Gly Ile Thr Leu Gly Met 
                725                 730                 735     


Asp Glu Leu Tyr Lys 
            740     


