                               SEQUENCE LISTING	

<110>  F. Hoffmann - La Roche AG, Basel (CH)
       Roche Diagnostics GmbH, Mannheim (DE)
 
<120> SYSTEM AND METHOD FOR PRODUCING FUNCTIONALLY DISTINCT NUCLEIC 
      ACID LIBRARY ENDS THROUGH USE OF DEOXYINOSINE

<130> 27053 WO

<140>
<141>

<150> 61/387,512
<151> 2010-09-29

<160> 16    

<170> PatentIn version 3.5

<210> 1
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (2)..(2)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (7)..(7)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (12)..(12)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (16)..(16)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (19)..(19)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (23)..(23)
<223> Deoxyinosine

<400> 1
cntatcncct gngtgnctng gcngtcgact                                        30


<210> 2
<211> 29
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 2
gtcgactgcc aaggcacaca ggggatagg                                         29


<210> 3
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 3
cgtatcgcct gggtggctgg gcggtcgact                                        30


<210> 4
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 4
agtcgactgc caaggcacac aggggatagg                                        30


<210> 5
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (2)..(2)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (6)..(6)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (9)..(9)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (12)..(12)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (16)..(16)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (19)..(19)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (22)..(22)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (25)..(25)
<223> Deoxyinosine

<400> 5
cntatnccnt gngtgnctng gnagncgact                                        30


<210> 6
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 6
cgtatgccgt gggtggctgg ggaggcgact                                        30


<210> 7
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (2)..(2)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (6)..(6)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (9)..(9)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (12)..(12)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (16)..(16)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (22)..(22)
<223> Deoxyinosine

<400> 7
cntatnccnt gngtgncttg gnagtcgact                                        30


<210> 8
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 8
cgtatgccgt gggtggcttg ggagtcgact                                        30


<210> 9
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> misc_feature
<222> (1)..(5)
<223> Phosphorothioate linkage

<220>
<221> modified_base
<222> (2)..(2)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (7)..(7)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (12)..(12)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (16)..(16)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (19)..(19)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (23)..(23)
<223> Deoxyinosine

<220>
<221> misc_feature
<222> (26)..(30)
<223> Phosphorothioate linkage 

<400> 9
cntatcncct gngtgnctng gcngtcgact                                        30


<210> 10
<211> 29
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> misc_feature
<222> (1)..(5)
<223> Phosphorothioate linkage

<220>
<221> misc_feature
<222> (25)..(29)
<223> Phosphorothioate linkage

<400> 10
gtcgactgcc aaggcacaca ggggatagg                                         29


<210> 11
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> misc_feature
<222> (1)..(5)
<223> Phosphorothioate linkage

<220>
<221> modified_base
<222> (2)..(2)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (6)..(6)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (9)..(9)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (12)..(12)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (16)..(16)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (19)..(19)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (22)..(22)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (25)..(25)
<223> Deoxyinosine

<220>
<221> misc_feature
<222> (26)..(30)
<223> Phosphorothioate linkage 

<400> 11
cntatnccnt gngtgnctng gnagncgact                                        30


<210> 12
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> misc_feature
<222> (1)..(5)
<223> Phosphorothioate linkage

<220>
<221> modified_base
<222> (2)..(2)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (6)..(6)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (9)..(9)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (12)..(12)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (16)..(16)
<223> Deoxyinosine

<220>
<221> modified_base
<222> (22)..(22)
<223> Deoxyinosine

<220>
<221> misc_feature
<222> (26)..(30)
<223> Phosphorothioate linkage 

<400> 12
cntatnccnt gngtgncttg gnagtcgact                                        30


<210> 13
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> misc_feature
<222> (2)..(6)
<223> Phosphorothioate linkage

<220>
<221> misc_feature
<222> (26)..(30)
<223> Phosphorothioate linkage

<400> 13
agtcgactgc caaggcacac aggggatagg                                        30


<210> 14
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 14
cctatcccct gtgtgccttg gcagtcgact                                        30


<210> 15
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 15
agtcgaccgc ccagccaccc aggcgatacg                                        30


<210> 16
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 16
agtcgaccac ccaggcacac aggggatagg                                        30


