                         SEQUENCE LISTING

<110>  Universitat de Barcelona
       Fundaci Privada Institut de Recerca Biomdica
 
<120>  Protease-resistant compounds useful as shuttles through the 
       blood-brain barrier and shuttle-cargo constructs

<130>  AVCRI173

<150>  ES P201230294
<151>  2012-02-27

<160>  6     

<170>  PatentIn version 3.5

<210>  1
<211>  12
<212>  PRT
<213>  Artificial sequence

<220>
<223>  D amino acids peptide shuttle

<400>  1

Pro Trp Val Pro Ser Trp Met Pro Pro Arg His Thr 
1               5                   10          


<210>  2
<211>  13
<212>  PRT
<213>  Artificial sequence

<220>
<223>  D amino acids peptide shuttle

<400>  2

Gly Pro Trp Val Pro Ser Trp Met Pro Pro Arg His Thr 
1               5                   10              


<210>  3
<211>  7
<212>  PRT
<213>  Artificial sequence

<220>
<223>  cargo D- amino acids


<220>
<221>  MOD_RES
<222>  (2)..(2)
<223>  Xaa at position 2 is N-methylphenylalanine

<220>
<221>  MOD_RES
<222>  (3)..(3)
<223>  Xaa at position 3 is N-naphtylalanine

<400>  3

Ala Xaa Xaa Val Leu Lys Lys 
1               5           


<210>  4
<211>  19
<212>  PRT
<213>  Artificial sequence

<220>
<223>  Cargo coupled to shuttle peptide


<220>
<221>  MOD_RES
<222>  (2)..(2)
<223>  Xaa at position 2 is N-methylphenylalanine

<220>
<221>  MOD_RES
<222>  (3)..(3)
<223>  Xaa at position 3 is N-napthylalanine

<400>  4

Ala Xaa Xaa Val Leu Lys Lys Pro Trp Val Pro Ser Trp Met Pro Pro 
1               5                   10                  15      


Arg His Thr 
            


<210>  5
<211>  12
<212>  PRT
<213>  Artificial sequence

<220>
<223>  L-amino acids peptide

<400>  5

Thr His Arg Pro Pro Met Trp Ser Pro Val Trp Pro 
1               5                   10          


<210>  6
<211>  12
<212>  PRT
<213>  Artificial sequence

<220>
<223>  D-amino acids peptide

<400>  6

Thr His Arg Pro Pro Met Trp Ser Pro Val Trp Pro 
1               5                   10          


