                         SEQUENCE LISTING

<110>  Arrowhead Madison Inc.
       Cheng, Weijun
       So, Wong
       Almeida, Aaron  M
       Rozema, David  B
       Blokhin, Andrei  V
       Carlson, Jeffrey  C
 
<120>  Polyconjugates for Delivery of RNAi triggers to Tumor Cells In 
       Vivo

<130>  30622 US1

<150>  61863056
<151>  2013-08-07

<160>  4     

<170>  PatentIn version 3.5

<210>  1
<211>  13
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  RGD integrin binding peptide


<220>
<221>  misc_feature
<222>  1, 3, 5, 9, 11, 13
<223>  Xaa can be any naturally occurring amino acid


<400>  1

Xaa Cys Xaa Cys Xaa Arg Gly Asp Xaa Cys Xaa Cys Xaa
1               5                   10


<210>  2
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  RGD integrin binding peptide

<400>  2

Ala Cys Asp Cys Arg Gly Asp Cys Phy Cys
1               5                   10      
  

<210>  3
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Mouse Aha1 siRNA sense strand sequence


<220>
<221>  modified_base
<222>  1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223>  /mod_base = "2'-deoxy-2'-flouro corresponding nucleoside"

<220>
<221>  modified_base
<222>  2, 4, 6, 8, 10, 12, 14, 16, 18
<223>  /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221>  modified_base
<222>  20
<223>  /mod_base = "3'-3'-linked deoxythymidine"

<400>  3
ggaugaagug gagauuagut                                                   20


<210>  4
<211>  21
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  mouse Aha1 siRNA antisense strand sequence


<220>
<221>  modified_base
<222>  2, 4, 6, 8, 10, 12, 14, 16, 18
<223>  /mod_base = "2'-deoxy-2'-flouro corresponding nucleoside"

<220>
<221>  modified_base
<222>  2, 21
<223>  /mod_base = "5'-phosphorothioate nucleoside"
<220>
<221>  modified_base
<222>  3, 5, 7, 9, 11, 13, 15, 17, 19
<223>  /mod_base = "2'-O-methyl corresponding nucleoside
"
<400>  4
acuaaucucc acuucaucct t                                                 21

<210>  5
<211>  12
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  RGD integrin binding peptide

<400>  5

Ala Cys Asp Cys Arg Gly Asp Cys Phy Cys Gly Lys
1               5                   10


