                         SEQUENCE LISTING

<110>  Protagen AG
 
<120>  Markersequenzen zur Diagnose und Stratifizierung von SLE 
       Patienten

<130>  PRO132-02EP 2014 01

<160>  1587  

<170>  PatentIn version 3.3

<210>  1
<211>  1320
<212>  DNA
<213>  Homo sapiens

<400>  1
ggtcaggttg ttcagttcaa actgagcgat attggtgaag gtattcgtga agttaccgtg     60

aaagaatggt atgtgaaaga aggtgatacc gtcagccagt ttgatagcat ttgtgaagtt    120

cagagcgata aagcaagcgt taccattacc agccgttatg atggtgttat caaaaaactg    180

tactacaacc tggatgatat tgcctatgtt ggtaaaccgc tggttgatat tgaaaccgaa    240

gcactgaaag atagcgaaga agatgttgtt gaaacaccgg cagttagcca tgatgaacat    300

acccatcaag aaatcaaagg tcgtaaaacc ctggcaactc cggcagttcg tcgtctggca    360

atggaaaata acattaaact gagtgaagtt gtgggcagcg gtaaagatgg tcgtattctg    420

aaagaagata tcctgaacta cctggaaaaa cagaccggtg caattctgcc tccgagcccg    480

aaagttgaaa ttatgcctcc gcctccgaaa ccgaaagata tgaccgttcc gattctggtt    540

agcaaaccgc ctgtttttac cggcaaagat aaaaccgaac cgattaaagg ttttcagaaa    600

gccatggtta aaaccatgag cgcagccctg aaaattccgc attttggtta ttgtgatgaa    660

atcgatctga ccgaactggt gaaactgcgt gaagaactga aaccgattgc atttgcacgt    720

ggtattaaac tgtcatttat gccgtttttt ctgaaagcag caagcctggg tctgctgcag    780

tttccgatcc tgaatgcaag cgttgatgaa aattgtcaga acatcaccta taaagccagc    840

cataacattg gtattgcaat ggataccgaa cagggtctga ttgttccgaa tgttaaaaat    900

gttcagattt gcagcatctt tgatatcgcc accgaactga atcgtctgca gaaactgggt    960

agcgttagcc agctgagcac caccgatctg acaggtggca cctttaccct gagtaatatt   1020

ggtagcattg gtggtacatt tgccaaaccg gttattatgc caccggaagt tgcaattggt   1080

gccctgggta gcattaaagc aattccgcgt tttaatcaga aaggcgaagt ttataaagcc   1140

cagatcatga atgttagctg gtcagcagat catcgtgtta ttgatggtgc caccatgagc   1200

cgttttagca atctgtggaa aagctatctg gaaaatccgg catttatgct gctggatctg   1260

aaaagatctt aagcggccgc ctgggcctca tgggccttcc tttcactgcc cgctttccag   1320


<210>  2
<211>  1944
<212>  DNA
<213>  Homo sapiens

<400>  2
atgtggcgcg tctgtgcgcg acgggctcag aatgtagccc catgggcggg actcgaggct     60

cggtggacgg ccttgcagga ggtacccgga actccacgag tgacctcgcg atctggcccg    120

gctcccgctc gtcgcaacag cgtgactaca gggtatggcg gggtccgggc actgtgcggc    180

tggaccccca gttctggggc cacgccgcgg aaccgcttac tgctgcagct tttggggtcg    240

cccggccgcc gctattacag tcttcccccg catcagaagg ttccattgcc ttctctttcc    300

cccacaatgc aggcaggcac catagcccgt tgggaaaaaa aagaggggga caaaatcaat    360

gaaggtgacc taattgcaga ggttgaaact gataaagcca ctgttggatt tgagagcctg    420

gaggagtgtt atatggcaaa gatacttgtt gctgaaggta ccagggatgt tcccatcgga    480

gcgatcatct gtatcacagt tggcaagcct gaggatattg aggcctttaa aaattataca    540

ctggattcct cagcagcacc taccccacaa gcggccccag caccaacccc tgctgccact    600

gcttcgccac ctacaccttc tgctcaggct cctggtagct catatccccc tcacatgcag    660

gtacttcttc ctgccctctc tcccaccatg accatgggca cagttcagag atgggaaaaa    720

aaagtgggtg agaagctaag tgaaggagac ttactggcag agatagaaac tgacaaagcc    780

actataggtt ttgaagtaca ggaagaaggt tatctggcaa aaatcctggt ccctgaaggc    840

acaagagatg tccctctagg aaccccactc tgtatcattg tagaaaaaga ggcagatata    900

tcagcatttg ctgactatag gccaaccgaa gtaacagatt taaaaccaca agtgccacca    960

cctaccccac ccccggtggc cgctgttcct ccaactcccc agcctttagc tcctacacct   1020

tcagcaccct gcccagctac tcctgctgga ccaaagggaa gggtgtttgt tagccctctt   1080

gcaaagaagt tggcagtaga gaaagggatt gatcttacac aagtaaaagg gacaggacca   1140

gatggtagaa tcaccaagaa ggatatcgac tcttttgtgc ctagtaaagt tgctcctgct   1200

ccggcagctg ttgtgcctcc cacaggtcct ggaatggcac cagttcctac aggtgtcttc   1260

acagatatcc caatcagcaa cattcgtcgg gttattgcac agcgattaat gcaatcaaag   1320

caaaccatac ctcattatta cctttctatc gatgtaaata tgggagaagt tttgttggta   1380

cggaaagaac ttaataagat attagaaggg agaagcaaaa tttctgtcaa tgacttcatc   1440

ataaaagctt cagctttggc atgtttaaaa gttcccgaag caaattcttc ttggatggac   1500

acagttataa gacaaaatca tgttgttgat gtcagtgttg cggtcagtac tcctgcagga   1560

ctcatcacac ctattgtgtt taatgcacat ataaaaggag tggaaaccat tgctaatgat   1620

gttgtttctt tagcaaccaa agcaagagag ggtaaactac agccacatga attccagggt   1680

ggcactttta cgatctccaa tttaggaatg tttggaatta agaatttctc tgctattatt   1740

aacccacctc aagcatgtat tttggcaatt ggtgcttcag aggataaact ggtccctgca   1800

gataatgaaa aagggtttga tgtggctagc atgatgtctg ttacactcag ttgtgatcac   1860

cgggtggtgg atggagcagt tggagcccag tggcttgctg agtttagaaa gtaccttgaa   1920

aaacctatca ctatgttgtt gtaa                                          1944


<210>  3
<211>  1313
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (835)..(835)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (837)..(837)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (859)..(859)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (882)..(882)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (913)..(913)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (925)..(925)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (930)..(930)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (947)..(947)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (958)..(958)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (994)..(994)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1012)..(1012)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1021)..(1021)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1043)..(1043)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1060)..(1060)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1062)..(1062)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1065)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1069)..(1069)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1079)..(1079)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1083)..(1083)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1091)..(1091)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1094)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1115)..(1115)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1117)..(1117)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1119)..(1120)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1128)..(1128)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1140)..(1142)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1153)..(1153)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1157)..(1158)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1188)..(1188)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1190)..(1190)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1202)..(1202)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1209)..(1210)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1213)..(1213)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1220)..(1220)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1224)..(1224)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1231)..(1232)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1234)..(1234)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1243)..(1243)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1246)..(1246)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1248)..(1248)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1258)..(1258)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1265)..(1266)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1273)..(1273)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1287)..(1287)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1306)..(1306)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1309)..(1309)
<223>  n is a, c, g, or t

<400>  3
agagaaatta ctatgagagg atcgcatcac catcaccatc acggatccta tttaggtgac     60

actatagaat cgtcgaccca cgcgtccgtt ggctttcctt ggagtgaaat caggaacatc    120

tctttcaatg acaaaaagtt tgtcattaaa cccatcgaca agaaggcacc tgactttgtg    180

ttttatgccc cacgtctgag aatcaacaag cggatcctgc agctctgcat gggcaaccat    240

gagttgtata tgcgccgcag gaagcctgac accatcgagg tgcagcagat gaaggcccag    300

gcccgggagg agaagcatca gaagcagctg gagcggcaac agctggaaac agagaagaaa    360

aggagagaaa ccgtggagag agagaaagag cagatgatgc gcgagaagga ggagttgatg    420

ctgcggctgc aggactatga ggagaagaca aagaaggcag agagagagct ctcggagcag    480

attcagaggg ccctgcagct ggaggaggag aggaagcggg cacaggagga ggccgagcgc    540

ctagaggctg accgtatggc tgcactgcgg gctaaggagg agctggagag acaggcggtg    600

gatcagataa agagccagga gcagctggct gcggagcttg cagaatacac tgccaagatt    660

gccctcctgg aagaggcgcg gaggcgcaag gaggatgaag ttgaagagtg gcagcacagg    720

gccaaagaag cccaggatga cctggtgaag accaaggagg agctgcacct ggtgatgaca    780

gcacccccgc ccccaccacc ccccgtgtac gagccggtga gctaccatgt ccagnanagc    840

ttgcaggatg agggcgcana gcccacgggc tacagcgcgg anctgtctag tgagggcatc    900

cgggatgacc gcnatgagga aaacncatcn ctgaggcaaa aaaaacnagc gtgtgcancg    960

gcagctgctg accctgaaca ccgagctntt ccangcccga aatgaaaata anagnacccc   1020

natgacttcc tccccaacga aancttgagg cagggccggn anaantacna aaccctgcng   1080

canatccggg nggnaacccc aaccacccct ccacnantnn aggccctnta aacccggccn   1140

nnacaagggc aangggnncc taagggggcc ttcccccccc cccccttntn ttttggccca   1200

anctaagann ccncaatccn ttcnttaaaa nntnccccaa aanttntngg ggaacaangg   1260

gcccnntttt ttnccctttt aatgccnagg gggattcccc aatttncanc ccc          1313


<210>  4
<211>  726
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (725)..(726)
<223>  n is a, c, g, or t

<400>  4
agaattacta tgagaggtcg catcccatca ccatcacgga tcctatttag gtgacactat     60

agaatcgtcg actctggacc ttggctgtca ctcagttaac agtgttctaa ctattaacgc    120

tacgatgcct gaacctacca agtctgctcc tgccccaaag aagggctcca agaaggcggt    180

gactaaggct cagaagaagg acgggaagaa gcgcaagcgc agccgcaagg agagctattc    240

agtgtatgtg tacaaggtgc tgaagcaggt ccatcccgac accggcatct cttccaaggc    300

aatggggatc atgaattcct tcgtcaacga catcttcgag cgcatcgcag gcgaggcttc    360

ccgcctggcg cattacaaca agcgctcgac catcacctcc agggagatcc agacggccgt    420

gcgcctgctg cttccggggg agctggccaa gcacgccgtg tcggagggca ccaaggccgt    480

caccaagtac accagttcca agtaactttg ccaaatttcc aagttgatcg tgatgttgat    540

ccgggactcg gtgtggtgac ggcccgccct gagcgcgaaa gtgcacgctc ttgacaactt    600

ccttatgttt ggagctttct ccaccaccac ccccgcccat tttcttgtaa aatttttgcc    660

atgcagatat gtaataactg caagtaaagg ctgaagacaa tgtgagctga acacggaact    720

attann                                                               726


<210>  5
<211>  963
<212>  DNA
<213>  Homo sapiens

<400>  5
atgtctaagt cagagtctcc taaagagccc gaacagctga ggaagctctt cattggaggg     60

ttgagctttg aaacaactga tgagagcctg aggagccatt ttgagcaatg gggaacgctc    120

acggactgtg tggtaatgag agatccaaac accaagcgct ccaggggctt tgggtttgtc    180

acatatgcca ctgtggagga ggtggatgca gctatgaatg caaggccaca caaggtggat    240

ggaagagttg tggaaccaaa gagagctgtc tccagagaag attctcaaag accaggtgcc    300

cacttaactg tgaaaaagat atttgttggt ggcattaaag aagacactga agaacatcac    360

ctaagagatt attttgaaca gtatggaaaa attgaagtga ttgaaatcat gactgaccga    420

ggcagtggca agaaaagggg ctttgccttt gtaacctttg acgaccatga ctccgtggat    480

aagattgtca ttcagaaata ccatactgtg aatggccaca actgtgaagt tagaaaagcc    540

ctgtcaaagc aagagatggc tagtgcttca tccagccaaa gaggtcgaag tggttctgga    600

aactttggtg gtggtcgtgg aggtggtttc ggtgggaatg acaacttcgg tcgtggagga    660

aacttcagtg gtcgtggtgg ctttggtggc agccgtggtg gtggtggata tggtggcagt    720

ggggatggct ataatggatt tggtaatgat ggaagcaatt ttggaggtgg tggaagctac    780

aatgattttg ggaattacaa caatcagtct tcaaattttg gacccatgaa gggaggaaat    840

tttggaggca gaagctctgg cccctatggc ggtggaggcc aatactttgc aaaaccacga    900

aaccaaggtg gctatggcgg ttccagcagc agcagtagct atggcagtgg cagaagattt    960

taa                                                                  963


<210>  6
<211>  1284
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (5)..(5)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (828)..(828)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (852)..(852)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (917)..(917)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (933)..(933)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (941)..(941)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (943)..(943)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (953)..(953)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (961)..(961)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (992)..(992)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1024)..(1024)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1038)..(1039)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1053)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1058)..(1058)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1074)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1080)..(1080)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1099)..(1099)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1105)..(1105)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1123)..(1123)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1142)..(1142)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1149)..(1149)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1152)..(1152)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1154)..(1155)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1158)..(1158)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1165)..(1165)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1169)..(1169)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1173)..(1173)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1186)..(1186)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1193)..(1193)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1196)..(1196)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1204)..(1204)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1234)..(1234)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1238)..(1238)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1240)..(1240)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1242)..(1242)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1263)..(1263)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1275)..(1275)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1281)..(1282)
<223>  n is a, c, g, or t

<400>  6
nnatngagaa attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cgcgccgggt cccgtgcgga ggtgctcctc    120

gcagagttgt ttctcgagca gcggcagttc tcactacagc gccaggacga gtccggttcg    180

tgttcgtccg cggagatctc tctcatctcg ctcggctgcg ggaaatcggg ctgaagcgac    240

tgagtccgcg atggagagag aaaaggaaca gttccgtaag ctctttattg gtggcttaag    300

ctttgaaacc acagaagaaa gtttgaggaa ctactacgaa caatggggaa agcttacaga    360

ctgtgtggta atgagggatc ctgcaagcaa aagatcaaga ggatttggtt ttgtaacttt    420

ttcatccatg gctgaggttg atgctgccat ggctgcaaga cctcattcaa ttgatgggag    480

agtagttgag ccaaaacgtg ctgtagcaag agaggaatct ggaaaaccag gggctcatgt    540

aactgtgaag aagctgtttg ttggcggaat taaagaagat actgaggaac atcaccttag    600

agattacttt gaggaatatg gaaaaattga taccattgag ataattactg ataggcagtc    660

tggaaagaaa agaggctttg gctttgttac ttttgatgac catgatcctg tggataaaat    720

cgtattgcag aaataccata ccatcaatgg tcataatgca gaagtaagaa aggctttgtc    780

tagacaagaa atgcaggaag ttcagagttc taggagtgga aagaggangc aacttttggc    840

tttggggatt cncgtggtgg cggtggaaat ttatggaagt ggaaattaca atgatttgga    900

aatttataac cagcaancct tctaactacg gtncaatgaa nantggaaac ttnggtggta    960

ncaggaacat gggggggaac catatggtgg angaaactta tggtcccaga aaggcattgg   1020

aagnaaattg gggggttnnt ggtgggaagg aancccanac tgaaccttct tccnaatttn   1080

gccaggggcc ttcccnggna naaanagggn aagggatgga aanccccaag gtaaacaaaa   1140

cncctttcng gntnnccnaa aaaanaatng ttnaaggaaa cctttncccc canccnggca   1200

aaanatgccg ggaaatgggc aaaaaaaccc caancaantn cnaaaaccct ttttgggagg   1260

ggnttgggat ttttnaaaaa nntt                                          1284


<210>  7
<211>  750
<212>  DNA
<213>  Homo sapiens

<400>  7
atagagaatt actatgagag gtcgcatccc atcaccatca cggatcctat ttaggtgaca     60

ctatagaatc gtcgactctg gaccttggct gtcactcagt ttatggggct cagagactgg    120

agcaggaagc ccgcggccgg cttgagcggc agaagatcct ggaccagtca gaagccgaga    180

aagctcgcaa ggaacttttg gagctggagg ctctgagcat ggccgtggag agcaccggga    240

ctgccaaggc ggaggccgag tcccgtgcgg aggcagcccg gattgaggga gaagggtccg    300

tgctgcaggc caagctaaaa gcacaggcct tggccattga aacggaggct gagctccaga    360

gggtccagga ggtccgagag ctggaactgg tctatgcccg ggcccagctg gagctggagg    420

tgagcaaggc tcagcagctg gctgaggtgg aggtgaagaa gttcaagcag atgacagagg    480

ccataggccc cagcaccatc agggaccttg ctgtggctgg gcctgagatg caggtaaaac    540

tgctccagtc cctgggcctg aaatcaaccc tcatcaccga tggctccact cccatcaacc    600

tcttcaacac agcctttggg ctgctgggga tggggcccga gggccagccc ctgggcagaa    660

gggtggccag tgggcccagc ccctggggag gggatatccc cccagtctgg ttcagccctc    720

aagctcctga aaacaaccac gaggtgcctg                                     750


<210>  8
<211>  1103
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (104)..(104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (124)..(124)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (130)..(130)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (156)..(156)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (168)..(168)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (177)..(177)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (183)..(184)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (270)..(270)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (281)..(281)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (304)..(304)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (314)..(314)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (326)..(326)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (357)..(357)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (359)..(359)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (377)..(377)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (391)..(391)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (395)..(395)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (410)..(410)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (412)..(412)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (415)..(415)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (524)..(524)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (527)..(527)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (664)..(664)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (687)..(687)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (702)..(702)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (707)..(707)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (721)..(722)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (761)..(762)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (778)..(778)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (782)..(782)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (792)..(792)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (817)..(817)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (819)..(819)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (858)..(858)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (869)..(869)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (872)..(872)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (874)..(874)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (878)..(878)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (891)..(892)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (894)..(894)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (897)..(897)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (902)..(902)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (911)..(911)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (919)..(919)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (941)..(941)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (946)..(946)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (950)..(950)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (968)..(968)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (974)..(974)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (989)..(989)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (993)..(994)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1011)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1019)..(1019)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1026)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1041)..(1041)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1074)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1077)..(1077)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1084)..(1084)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1090)..(1090)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1098)
<223>  n is a, c, g, or t

<400>  8
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg tttcattgtg ggancattac aactgtgggc    120

tccnagtcan atgcagcaga tccgcatgtc ccttcncggg aaggctgngg tgctganggg    180

cannaacacc atgatgcgca aggccatccg agggcacctg gaaaacaacc cagctctgga    240

gaaactgctg cctcatatcc gggggaatgn gggctttgtg ntcaccaagg aggacctcac    300

tganatcagg gacntgttgc tggccnataa ggtgccagct gctgcccgtg ctggtgncnt    360

tgccccatgt gaagtcnctg tgccagccca naacnctggt ctcgggcccn anaanacctc    420

ctttttccag gctttaggta tcaccactaa aatctccagg ggcaccattg aaatcctgag    480

tgatgtgcag ctgatcaaga ctggagacaa agtgggagcc agcnaancca cgctgctgaa    540

catgctcaac atctccccct tctcctttgg gctggtcatc cagcaggtgt tcgacaatgg    600

cagcatctac aaccctgaag tgcttgatat cacagaggaa actctgcatt ctcgcttcct    660

gganggtgtc cgcaatgttg ccagtgnctg tctgcagatt gnctacncaa ctgttgcatc    720

nntaccccat tctatcatca acgggtacaa acgagtcctg nncttgtctg tggaaacnga    780

tnacaccttc cnacttgctg aaaaagtcaa ggccttncnt ggctgatcca tctgcctttg    840

tggctagctg cccctgtnac tgctgccana ananctgntt cctgctgctg nngnaanccc    900

anctaaaggt ngaaacccna agaaaaaatc cgaaggaatc ngaacnaagn atatgggaat    960

ttgggncncc tttnactaaa tccccccana aannaaccct actttaaccc ngtttttant   1020

ttgccnaaac aaagnaaaat naagggctta acttctttna aaaaaaaaaa aaanaanggg   1080

cggnccgccn cccnnnangg ggg                                           1103


<210>  9
<211>  544
<212>  DNA
<213>  Homo sapiens

<400>  9
tagagaaatt aactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg gggtgaggcc ctcacttcat ccggcgacta    120

gcaccgcgtc cggcagcgcc agccctacac tcgcccgcgc catggcctct gtctccgagc    180

tcgcctgcat ctactcggcc ctcattctgc acgacgatga ggtgacagtc acggaggata    240

agatcaatgc cctcattaaa gcagccggtg taaatgttga gcctttttgg cctggcttgt    300

ttgcaaaggc cctggccaac gtcaacattg ggagcctcat ctgcaatgta ggggccggtg    360

gacctgctcc agcagctggt gctgcaccag caggaggtcc tgccccctcc actgctgctg    420

ctccagctga ggagaagaaa gtggaagcaa agaaagaaga atccgaggag tctgatgatg    480

acatgggctt tggtcttttt gactaaacct cttttataac atgttcaata aaaagctgaa    540

cttt                                                                 544


<210>  10
<211>  486
<212>  DNA
<213>  Homo sapiens

<400>  10
tactatgaga ggtcgcatca ccatcaccat cacggatcct atttaggtga cactatagaa     60

tcgtcgactc tggaccttgg ctgtcactca gttgccgcga tgcgctacgt cgcctcctac    120

ctgctggctg ccctaggggg caactcctcc cccagcgcca aggacatcaa gaagatcttg    180

gacagcgtgg gtatcgaggc ggacgacgac cggctcaaca aggttatcag tgagctgaat    240

ggaaaaaaca ttgaagacgt cattgcccag ggtattggca agcttgccag tgtacctgct    300

ggtggggctg tagccgtctc tgctgcccca ggctctgcag cccctgctgc tggttctgcc    360

cctgctgcag cagaggagaa gaaagatgag aagaaggagg agtctgaaga gtcagatgat    420

gacatgggat ttggcctttt tgattaaatt cctgctcccc tgcaaataaa gcctttttac    480

acatct                                                               486


<210>  11
<211>  857
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (797)..(798)
<223>  n is a, c, g, or t

<400>  11
ccatagagag aatactatga gaggatgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac tctggacctt ggctgtcact cagttagggg tgacagtcca    120

aagattgact tggccggcag ttcgctatct ggcatcctgg acaaagatct ctcggaccgc    180

agcaatgaca ttgacttaga aggttttgac tccgtggtat catctactga gaaactcagt    240

catccgacca caagcagacc aaaagctaca gggaggcggc ctccgtccca gtccctcaca    300

tcttcatccc tttcaagccc tgatatcttc gactccccaa gtcccgaaga ggataaggag    360

gaacacattt cacttgcgca cagaggagtg gacgcgtcaa agaaaacttc caagactgtt    420

accatatccc aagtgtctga caacaaagca tccctgccgc ccaagccggg gaccatggca    480

gcaggtggcg gtgggccagc ccctctgtcc tcagcggcgc cctcccccct gtcatcctct    540

ttgggaacag ctggacacag agccaactcc ccgtctctgt tcggcacgga aggaaaacca    600

aagatggagc ctgcggccag cagccaggcg gccgtggagg agctaaggac acaggtccgc    660

gagctgagga gcatcatcga gaccatgaag gaccagcaga aacgagagat taaacagtta    720

ttgtctgagt tggatgaaga gaagaaaatc cggcttcggt tgcagatgga agtgaacgac    780

ataaagaaag ctctacnnat caaatgaata ctttgatcat gaaatgtcac attattcatc    840

ctgagtccga agactca                                                   857


<210>  12
<211>  848
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (711)..(711)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (782)..(782)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (789)..(789)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (796)..(796)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (803)..(803)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (811)..(811)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (816)..(817)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (828)..(833)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (835)..(842)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (844)..(845)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (847)..(848)
<223>  n is a, c, g, or t

<400>  12
nnnaagatat attgacttac ctataaatag gcgtatcacg aggccctttc gtcttcacct     60

cgagaaatca taaaaaattt atttgctttg tgagcggata acaattataa tagattcaat    120

tgtgagcgga taacaatttc acacagaatt cattaaagag gagaaattaa ctatgagagg    180

atcgcatcac catcaccatc acggtcgacc cacgcgtccg cccacgcgtc cgggattctg    240

ttgtgtcata attcactctc gccacgaaga gagtcttgaa gtgtacggac ctatcaaaag    300

aatacacatg gtctacagta agcggtcagg aaagccccgt ggctatgcct tcatcgagta    360

cgaacacgag cgagacatgc actccgctta caaacacgca gatggcaaga agattgatgg    420

caggagggtc cttgtggacg tggagagggg ccgaaccgtg aagggctgga ggccccggcg    480

gctaggagga ggcctcggtg gtaccagaag aggaggggct gatgtgaaca tccggcattc    540

aggccgcgat gacacctccc gctacgatga gaggcccggg ccctccccgc ttccgcacag    600

ggaccgggac cgggaccgtg agcgggagcg caaaaagcgg aaccgggaac aaaacaggag    660

ccagaacggg caagctcccg cccccgggac cggcggaagg gctcacggaa nccccacaag    720

gaggacggga ggccccccgg gaacggaaca aggaacagga cgggaccgga aacgggaaac    780

cncccgaanc ggaaanggcc ccnggggaaa nggaanncag gaagaacnnn nnngnnnnnn    840

nngnnann                                                             848


<210>  13
<211>  977
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (896)..(896)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (914)..(914)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (918)..(918)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (925)..(925)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (958)..(958)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (965)..(967)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (969)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (971)..(971)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (973)..(973)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (976)..(976)
<223>  n is a, c, g, or t

<400>  13
naatagagaa attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cgatttgatc ctctgtgact gtgatgagtt    120

cagaaagatc aagccaaaga actccaaaca agcagaaagg gaagagaagc gagtcctcgg    180

tctggtgctg ctgcgagggg agaatctggt ctcaatgaca gtagagggac ctcctcccaa    240

agatactggt attgctcgag ttccacttgc tggagctgcc gggggcccag ggatcggcag    300

ggctgctggc agaggaatcc cagctggggt tcccatgccc caggctcctg caggacttgc    360

tgggccagtc cgtggggttg gcgggccatc ccaacaggtg atgaccccac aaggaagagg    420

tactgttgca gccgctgcag ctgctgccac agccagtatt gccggggctc caacccagta    480

cccacctggc cgtgggggtc ctcccccacc tatgggccga ggagcacccc ctccaggcat    540

gatgggccca cctcctggta tgagacctcc tatgggtccc ccaatgggga tcccccctgg    600

aagagggact ccaatgggca tgccccctcc gggaatgcgg cctcctcccc ctgggatgcg    660

aggccttctt tgacccttgg ccacagagta tggaagtagc tccgcagagg cgtgggctcg    720

attcctcagg gccacgttac cacagacctg tttgtttctt atgctgttgt tcgtggagtc    780

tcatgggatt gtctggtttt cccttacagg gccccctccc ccgggaatgc gcccaccaag    840

gccctaaact catcttggcc ctcctcaact ccctgcctgt ttcccgtaag ctgtanataa    900

tcctttttat ctcntgtngc ctatnaaact ggtttaaaaa aaaactcctt aaaaaaanct    960

tttannnana nanaana                                                   977


<210>  14
<211>  915
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (797)..(797)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (819)..(819)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (824)..(824)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (865)..(865)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (873)..(873)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (886)..(887)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (896)..(896)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (907)..(908)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (914)..(914)
<223>  n is a, c, g, or t

<400>  14
atagagaaat nactatgaga ggatcgcatc accatcacca tcacggaatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gagaagcatc aagttttaac tgtggacatt    120

ggatttggtg gaacagcaat catgactgtt ggcaagagta gcaagatgct gcagcacatt    180

gactatagaa tgagatgtat cctgcaagat ggccgaatct tcattggcac ctttaaggct    240

tttgacaagc atatgaattt gatcctctgt gattgtgatg agttcagaaa gatcaagcca    300

aagaatgcga agcaaccaga gcgtgaagaa aagcgggttt tgggtctggt gttgctgcgt    360

ggggagaact tggtatccat gactgtggag gggccacccc ccaaagatac tggcattgct    420

cgggtaccac ttgctggagc tgctggaggc cctggggttg gtagggcagc tggtagagga    480

gtaccagctg gtgtgccaat tccccaggcc cctgctggat tggcaggccc tgtccgagga    540

gttgggggac catcccagca ggtaatgact ccacagggaa gaggcactgt agcagctgct    600

gctgttgctg cgactgccag tattgctgga gccccaacac agtacccacc aggacggggc    660

actccgcccc cacccgtcgg cagagcaacc ccacctccag gcattatggc tcctccacct    720

ggtatgagac cacccatggg cccaccaatt gggcttcccc ctgctcgagg gacgccaata    780

ggcatgccgc ctccggnaat gagaccccct ccaccaggna ttanaggtcc acctcccccc    840

aggaatgcgt ccaccaagac cttancatac tgntgatcca tctcanncac tttttnccct    900

gcaatgnntc ttgng                                                     915


<210>  15
<211>  1443
<212>  DNA
<213>  Homo sapiens

<400>  15
atggcaggtg ggggcggcga cctgagcacc aggaggctga atgaatgtat ttcaccagta     60

gcaaatgaga tgaaccatct tcctgcacac agccacgatt tgcaaaggat gttcacggaa    120

gaccagggtg tagatgacag gctgctctat gacattgtat tcaagcactt caaaagaaat    180

aaggtggaga tttcaaatgc aataaaaaag acatttccat tcctcgaggg cctccgtgat    240

cgtgatctca tcacaaataa aatgtttgaa gattctcaag attcttgtag aaacctggtc    300

cctgtacaga gagtggtgta caatgttctt agtgaactgg agaagacatt taacctgcca    360

gttctggaag cactgttcag cgatgtcaac atgcaggaat accccgattt aattcacatt    420

tataaaggct ttgaaaatgt aatccatgac aaattgcctc tccaagaaag tgaagaagaa    480

gagagggagg agaggtctgg cctccaacta agtcttgaac aaggaactgg tgaaaactct    540

tttcgaagcc tgacttggcc accttcgggt tccccatctc atgctggtac aaccccacct    600

gaaaatggac tctcagagca cccctgtgaa acagaacaga taaatgcaaa gagaaaagat    660

acaaccagtg acaaagatga ttcgctagga agccaacaaa caaatgaaca atgtgctcaa    720

aaggctgagc caacagagtc ctgcgaacaa attgctgtcc aagtgaataa tggggatgct    780

ggaagggaga tgccctgccc gttgccctgt gatgaagaaa gcccagaggc agagctacac    840

aaccatggaa tccaaattaa ttcctgttct gtgcgactgg tggatataaa aaaggaaaag    900

ccattttcta attcaaaagt tgagtgccaa gcccaagcaa gaactcatca taaccaggca    960

tctgacataa tagtcatcag cagtgaggac tctgaaggat ccactgacgt tgatgagccc   1020

ttagaagtct tcatctcagc accgagaagt gagcctgtga tcaataatga caacccttta   1080

gaatcaaatg atgaaaagga gggccaagaa gccacttgct cacgacccca gattgtacca   1140

gagcccatgg atttcagaaa attatctaca ttcagagaaa gttttaagaa aagagtgata   1200

ggacaagacc acgacttttc agaatccagt gaggaggagg cgcccgcaga agcctcaagc   1260

ggggcactga gaagcaagca tggtgagaag gctcctatga cttctagaag tacatctact   1320

tggagaatac ccagcaggaa gagacgtttc agcagtagtg acttttcaga cctgagtaat   1380

ggagaagagc ttcaggaaac ctgcagctca tccctaagaa gagggtcagg taaagaagat   1440

tag                                                                 1443


<210>  16
<211>  1165
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (892)..(892)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (913)..(913)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (919)..(919)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (921)..(921)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (931)..(931)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (942)..(942)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (990)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (995)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1011)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1013)..(1013)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1027)..(1027)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1044)..(1044)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1051)..(1051)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1067)..(1067)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1076)..(1076)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1081)..(1081)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1085)..(1085)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1091)..(1092)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1099)..(1099)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1107)..(1107)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1121)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1144)..(1145)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1148)..(1148)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1157)..(1157)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1161)..(1161)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1165)..(1165)
<223>  n is a, c, g, or t

<400>  16
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc agaggagatc cgcgagaaac tgcagcaggt    120

gatgtccagg aggaaagaga tgaatgagaa gtgggaagcc cgctgggagc ggctccgcat    180

gttgctggag gtgtgccagt tctcgaggga tgcctctgtg gctgaggcgt ggctgattgc    240

ccaggagccc tacctggcca gcggggactt tggacacaca gtggacagtg tggagaagct    300

catcaagagg catgaggctt ttgagaagtc cacggccagc tgggcagagc gctttgctgc    360

cctggagaag cccaccacgc ttgagctgaa agaacgccag attgcagaga gacccgcaga    420

ggagactggg cctcaagagg aggaaggcga gacagcaggg gaggctccag tttcccacca    480

tgcggccacc gagagaacgt ccccggggga agaagaggga acgtggcctc agaacctgca    540

gcagccacca ccgccgggtc agcacaagga tgggcagaaa tccactgggg atgagaggcc    600

caccacggag cccctcttta aggtcctaga tacgcctctg agcgagggtg atgagcccgc    660

aacgctgccg gccccgcggg accatgggca gagtgtgcag atggaaggct acctgggccg    720

caagcatgac ctggaggggc ccaacaagaa ggcttccaac aggtcctgga acaacctgta    780

ctgtgtgctc aggaacagtg agctaacctt ctacaaggat gccaagaacc tggccctggg    840

gatgccctac catggggagg aacccctggc cctgaaacat gccatctgtg anattgctgc    900

caactacaaa aanaaaaanc ncgtctttaa nctgaagctg antatggcag cgagtggctc    960

ttccatggca agaatgaaga agaaatgctn tcctngcttc nagggcgtga ncncccccat   1020

caacgantcc caaaacatcc cccntcaagg ncaaaacctg cccctgnctt tccttnccgg   1080

ncccnaaccc nncctnggna aaaaaanaag gaaaaaaaat nccccttttc cccaaaaaaa   1140

tacnnggngg ggttggnggg ncccn                                         1165


<210>  17
<211>  1415
<212>  DNA
<213>  Homo sapiens

<400>  17
catatactga ctacctataa ataggcgtat ccgaggccct ttcgtcttca cctcgagaaa     60

tcataaaaaa tttatttgct ttgtgagcgg ataacaatta taatagattc aattgtgagc    120

ggataacaat ttcccacaga attcattaaa gaggagaaat taactatgag aggatcgcat    180

caccatcacc atcacggtcg acccacgcgt ccgcggaagt acaaagaaac agacctgcta    240

atacttttca aggacgatta ctttgccaaa aaaaatgaag aaagaaaaca aaataaagtg    300

gaagctaaat taagagctaa acaggagcaa gaagcaaaac aaaagttaga agaagatgct    360

gaaatgaaat ctctacaaga aaagattgga tgcttgctga aattttcggg tgatttagat    420

gatcagacct gtagagaaga tttacacata cttttctcaa atcatggtga aataaaatgg    480

atagacttcg tcagaggagc aaaagagggg ataattctat ttaaagaaaa agccaaggaa    540

gcattgggta aagccaaaga tgcaaataat ggtaacctac aattaaggaa ccaagaactg    600

acttgggaag tactagaagg agaggtggaa aaagaagccc tgaagaaaat aatacaagac    660

ccacaagaat ccctacacaa atggaagtca aaacgtccga aatttaaacg gaaaaggaag    720

ggtaataaag cttgcccccc ctgggtctgg taaaggaaaa gtacagtttc agggcaaaaa    780

acgcaatttg ctagcgatca tgaacatgac caacatgatg aaaaagggtg caactggacc    840

ctgggaaaac agcagaagaa aaacccgcca ccgaaatacc ccgcctcccc acccaccgaa    900

aacccaaaca gggcgcctgg gagaccccta atttcaccaa cccccttttt ctatctcctt    960

ttaaaaacgg cttagaccaa cccttggcta ccgcgggctt tcaaacggca aaccccactc   1020

agggccccct ccatgggccc gccgggccga aagcggaaac tctctctcgg cggcccacct   1080

cgtcctctct cctagcccca agcaagaacc ctcatagacg cactcgcacc cggctgggcg   1140

acaacccgcc accacatctg cgcaactcac aagccccggc gtgggggccc cccgccagac   1200

caaccagaac ccgcccccac gaccccgacg cagccgtgtt cgaaccacag ccgcggccct   1260

cagatcgctt tactccccac gcaaacccga caagcactac gaaaactatc ctagcaacct   1320

cgagatgctc acagccgaaa tacatatgga ccgctacacg cgccacaggt gaccgtacga   1380

cagagcacag aaccgtctac cctctcaccg cgctg                              1415


<210>  18
<211>  1105
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (760)..(760)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (793)..(793)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (817)..(817)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (839)..(839)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (887)..(887)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (894)..(894)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (914)..(914)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (920)..(920)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (925)..(925)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (928)..(928)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (937)..(937)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (940)..(940)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (951)..(951)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (963)..(963)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (979)..(979)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (991)..(991)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (996)..(996)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1000)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1017)..(1017)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1025)..(1025)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1029)..(1029)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1047)..(1048)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1055)..(1056)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1061)..(1061)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1063)..(1063)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1067)..(1067)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1075)..(1075)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1085)..(1085)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1089)..(1089)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<400>  18
tgagaaatta ctatgagagg atcgcatcac catcaccatc acggatccta tttaggtgac     60

actatagaat cgtcgaccca cgcgtccgcg gacgcgtggg cgcggtcccc ggccaggagc    120

aagcgcgccg gcgtgagcgg cggcggcaaa ggctgtgggg agggggcttc gcagatcccc    180

gagatgccgg agttcctgga agacccctcg gtcctgacaa aagacaagtt gaagagtgag    240

ttggtcgcca acaatgtgac gctgccggcc ggggagcagc gcaaagacgt gtacgtccag    300

ctctacctgc agcacctcac ggctcgcaac cggccgccgc tccccgccgg caccaacagc    360

aaggggcccc cggacttctc cagtgacgaa gagcgcgagc ccaccccggt cctcggctct    420

ggggccgccg ccgcgggccg gagccgagca gccgtcggca ggaaagccac aaaaaaaact    480

gataaaccca gacaagaaga taaagatgat ctagatgtaa cagagctcac taatgaagat    540

cttttggatc agcttgtgaa atacggagtg aatcctggtc ctattgtggg aacaaccagg    600

aagctatatg agaaaaagct tttgaaactg agggaacaag gaacagaatc aagatcttct    660

actcctctgc caacaatttc ttcttcagca gaaaatacaa ggcagaatgg aagtaatgat    720

tctgacagat acagtgacaa tgaagaaaac tctaaaatan agctcaagct tgagaaaaga    780

aaaaccacta aangggcaga ccaaagactc cagtaanact caagcaaaaa aaatttganc    840

acaattcaaa gctttttttc aacttggaat aacttgaaaa ctgaatngga caantggatt    900

tttcaaaaag gggnaacctn tgcangcntt ttactanggn aatctaaaaa naagggttca    960

aanaaaaaaa ttccaaggna aaaaggggtg naaaantttn naaanttttt ttttaanaan   1020

atggntccna attanttttn aaaaaannat ccccnnaanc ntnaaanttn taatnggctt   1080

ttaancaana aaattccttt ntttt                                         1105


<210>  19
<211>  1240
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (836)..(836)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (876)..(876)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (902)..(902)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (908)..(908)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (914)..(914)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (921)..(921)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (923)..(923)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (941)..(941)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (967)..(967)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1024)..(1024)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1050)..(1050)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1055)..(1055)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1065)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1068)..(1068)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1074)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1088)..(1088)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1108)..(1108)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1118)..(1118)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1128)..(1128)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1134)..(1134)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1140)..(1140)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1143)..(1143)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1146)..(1146)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1148)..(1148)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1154)..(1154)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1158)..(1158)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1171)..(1171)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1175)..(1175)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1187)..(1187)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1204)..(1204)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1209)..(1209)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1215)..(1215)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1219)..(1219)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1225)..(1225)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1227)..(1227)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1238)..(1239)
<223>  n is a, c, g, or t

<400>  19
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg acttcacctg ttctgtgaga aagatgggaa    120

ggccctttgc tgggtatgtg cccagtctcg gaaacaccgt gaccacgcca tggtccctct    180

tgaggaggct gcacaggagt accaggagaa gctccaggtg gcattagggg aactgagaag    240

aaagcaggag ttggctgaga agttggaagt ggaaattgca ataaagagag cagactggaa    300

gaaaacagtg gaaacacaga aatctaggat tcacgcagag tttgtgcagc aaaaaaactt    360

cctggttgaa gaagaacaga ggcagctgca ggagctggag aaggatgaga gggagcagct    420

gagaatcctg ggggagaaag aggccaagct ggcccagcag agccaggccc tacaggagct    480

catctcagag ctagatcgaa ggtgccacag ctcagcactg gaactgctgc aggaggtgat    540

aattgtcctg gaaaggagtg agtcctggaa cctgaaggac ctggatatta cctctccaga    600

actcaggagt gtgtgccatg tgccagggct gaagaagatg ctgaggacat gtgcagtcca    660

catcactctg gatccagaca cagccaatcc gtggctgata ctttcagaag atcggagaca    720

agtgaggctt ggagacaccc agcagagcat acctggaaat gaagagagat ttgatagtta    780

tcctatggtc ctgggtgccc agcactttca ctctggaaaa cattactggg aggtanatgt    840

gacaggaaag gaggcctggg acctgggtgt ctgcanagac tctgtgcgca ggaaggggca    900

cntttttngc ttanttccaa nantggcttc tggacaattt nggttgtgga acaaacaaaa    960

atatgangct ggcacctacc ccccaaactc cccctccccc tttcaggtgc ctcccatgcc   1020

aagnttggga tttttcctgg actttgaagn ctggnatggt tctcnttntt naanatccct   1080

tgaacaangg ctcccctcat ctactccntt ctttgaangg gccctttnaa gganctttgn   1140

ggnccntntt tcantccngg tttccatgga nggangaaaa aaacaanccc cccttaaccc   1200

tttntcccnt gaaanttgna ttccnanggg tcccccgnnc                         1240


<210>  20
<211>  1135
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (835)..(835)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (943)..(943)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (962)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (973)..(973)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (985)..(985)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (992)..(992)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1002)..(1002)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1017)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1029)..(1029)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1036)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1052)..(1052)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1062)..(1062)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1064)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1067)..(1067)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1084)..(1084)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1086)..(1086)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1088)..(1088)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1117)..(1117)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1120)..(1120)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1124)..(1124)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1128)..(1129)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1134)..(1135)
<223>  n is a, c, g, or t

<400>  20
antagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc ggtcaagaag gcagaaccac aaagcaagag    120

cctatgctct ttgcacttgc catttgttcc cagtgctccg acataagcac aaaacaagca    180

gcatttaaag ctgtttctga agtttgtcgc attcctaccc atctctttac ttttatccag    240

tttaagaaag atctgaagga aagcatgaaa tgtggcatgt ggggtcgtgc cctccggaag    300

gctatagcgg actggtacaa tgagaaaggt ggcatggccc ttgctctggc agttacaaaa    360

tataaacaga gaaatggctg gtctcacaaa gatctattaa gattgtcaca tcttaaacct    420

tccagtgaag gacttgcaat tgtgaccaaa tatattacaa agggctggaa agaagttcat    480

gaattgtata aagaaaaagc actctctgtg gagactgaaa aattattaaa gtatctggag    540

gctgtagaga aagtgaagcg cacaagagat gagctagaag tcattcatct aatagaagaa    600

catagattag ttagagaaca tcttttaaca aatcacttaa agtctaaaga ggtatggaag    660

gctttgttac aagaaatgcc gcttactgca ttactaagga atctaggaaa gatgactgct    720

aattcagtac ttgaaccagg aaattcagaa gtatctttag tatgtgaaaa actgtgtaat    780

gaaaaactat taaaaaaggc tcgtatacat ccatttcata ttttgatcgc attanaaact    840

tacaagacag gtcatggtct cagagggaaa ctgaagtggc gccctgatga aaaaattttg    900

aaagcattgg atgctgcttt ttataaaaca tttaaaaaca gtngaaccaa ctgggaaaac    960

gntttcttac tanctgntga tgtcngngcc tnctatgaac cnaanagttt tgggnannat   1020

accccaacnc tatacngttg ctgcaccaat gngcagggtt gncnncnaac aaaaaaaatc   1080

ttangnantt gcttttccca agaaangggn ccctggnccn gggncaanna aaann        1135


<210>  21
<211>  1226
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (795)..(795)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (908)..(908)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (923)..(923)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (928)..(928)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (947)..(947)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (969)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (975)..(975)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (985)..(985)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1010)..(1010)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1019)..(1019)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1022)..(1022)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1024)..(1024)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1056)..(1056)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1066)..(1066)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1081)..(1081)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1086)..(1086)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1092)..(1092)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1094)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1103)..(1103)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1117)..(1117)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1125)..(1125)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1127)..(1127)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1144)..(1144)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1148)..(1148)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1160)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1180)..(1180)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1182)..(1182)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1192)..(1192)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1196)..(1196)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1199)..(1199)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1205)..(1205)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1208)..(1208)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1211)..(1211)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1214)..(1214)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1216)..(1216)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1222)..(1222)
<223>  n is a, c, g, or t

<400>  21
attagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gctgccgtgc gcctgcggag cagcgtgccc    120

ggggtgcggc tcctgcagga ctcggtggac ttctcgctgg ccgacgccat caacaccgag    180

ttcaagaaca cccgcaccaa cgagaaggtg gagctgcagg agctgaatga ccgcttcgcc    240

aactacatcg acaaggtgcg cttcctggag cagcagaata agatcctgct ggccgagctc    300

gagcagctca agggccaagg caagtcgcgc ctgggggacc tctacgagga ggagatgcgg    360

gagctgcgcc ggcaggtgga ccagctaacc aacgacaaag cccgcgtcga ggtggagcgc    420

gacaacctgg ccgaggacat catgcgcctc cgggagaaat tgcaggagga gatgcttcag    480

agagaggaag ccgaaaacac cctgcaatct ttcagacagg atgttgacaa tgcgtctctg    540

gcacgtcttg accttgaacg caaagtggaa tctttgcaag aagagattgc ctttttgaag    600

aaactccacg aagaggaaat ccaggagctg caggctcaga ttcaggaaca gcatgtccaa    660

atcgatgtgg atgtttccaa gcctgacctc acggctgccc tgcgtgacgt acgtcagcaa    720

tatgaaagtg tggctgccaa gaacctgcag gaggcagaag aatggtacaa atccaagttt    780

gctgacctct ctgangctgc caaccggaac aatgacgccc tgcgccaggc aaagcaggag    840

tccactgagt accggagaca ggtgcagtcc ctcacctgtg aagtggatgc ccttaaagga    900

acaatgantc cttggaacgc canatgcntg aaatggaaaa aactttncgt tgaactgcta    960

ctaccaaana ctatnggccc ctgcnggatg aaattcaaat atgaagaagn aatggctcnt   1020

cncnttcttg aaaccaaaac tgctcatgtt aaatgncctt gaattnaaat nccccttacg   1080

naactnctga angnaagaaa aangattttc tgccctncaa atttncncct gaacctgagg   1140

aaanaacngg aatccccccn gggtgaaccc cccaaaagan cnttttataa angttnaant   1200

aaaanggngg nttnanaaat tntccc                                        1226


<210>  22
<211>  1208
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (920)..(920)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (927)..(927)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (939)..(939)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (995)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1018)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1027)..(1027)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1078)..(1078)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1081)..(1081)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1083)..(1083)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1086)..(1088)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1092)..(1092)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1100)..(1100)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1107)..(1107)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1111)..(1111)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1123)..(1123)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1137)..(1137)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1139)..(1139)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1147)..(1147)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1151)..(1151)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1153)..(1153)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1156)..(1156)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1160)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1171)..(1171)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1176)..(1176)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1180)..(1180)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1186)..(1186)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1191)..(1191)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1205)..(1205)
<223>  n is a, c, g, or t

<400>  22
aatagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gatcaagttc taaaggtctt tgcagcaaga    120

gatgatgagg cagctgcagt tgcactttcc tccctgattc atgctttgga tgacttagac    180

atggtggcca tagttcgata tgcttatgac aaaagagcta atcctcaagt cggcgtggct    240

tttcctcata tcaagcataa ctatgagtgt ttagtgtatg tgcagctgcc tttcatggaa    300

gacttgcggc aatacatgtt ttcatccttg aaaaacagta agaaatatgc tcccaccgag    360

gcacagttga atgctgttga tgctttgatt gactccatga gcttggcaaa gaaagatgag    420

aagacagaca cccttgaaga cttgtttcca accaccaaaa tcccaaatcc tcgatttcag    480

agattatttc agtgtctgct gcacagagct ttacatcccc gggagcctct acccccaatt    540

cagcagcata tttggaatat gctgaatcct cccgctgagg tgacaacgaa aagtcagatt    600

cctctctcta aaataaagac cctttttcct ctgattgaag ccaagaaaaa ggatcaagtg    660

actgctcagg aaattttcca agacaaccat gaagatggac ctacagctaa aaaattaaag    720

actgagcaag ggggagccca cttcagcgtc tccagtctgg ctgaaggcag tgtcacctct    780

gttggaagtg tgaatcctgc tgaaaacttc cgtgttctag tgaaacagaa gaaggccagc    840

tttgaggaag cgagtaacca gctcataaat cacatcgaac agtttttggg atactaatga    900

aacaccgtat ttttatgaan agcatanact gcatccganc cctccgggaa gaagccatta    960

agtttncaaa aaaacagcgc ttttaacaac ttccngnaag ccctncagaa aaaggggnaa   1020

ttaacantta aatcntttct gggaattggt ggccaggagg aatttcctga nccccaanag   1080

nanccnnngg anttctgccn cctgagnaac naaaagtttc ggncccccaa aaaaacnang   1140

ggaaacnccc ncnttntttn aaaaggggga nggganattn tggaangaaa nggcgggagg   1200

tgggnaac                                                            1208


<210>  23
<211>  1304
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (568)..(568)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1170)..(1170)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1199)..(1199)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1265)..(1265)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1287)..(1287)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1299)..(1299)
<223>  n is a, c, g, or t

<400>  23
cccccctaag agatactata gaggatcgca tcaccatcac catcacggtc gacccacgcg     60

tccgcccacg cgtccggggg aaggtggttc tgaagacgga tctgaggatg ggcttcccga    120

aggaatccat ctggataaaa atgatgatgg aggaaaaata aaacatctta catcttcaag    180

agagtgtagt tattgtggaa agtttttccg ttcaaattat tacctcaata ttcatctcag    240

aacgcataca ggtgaaaaac catacaaatg tgaattttgt gaatatgctg cagcccagaa    300

gacatctctg aggtatcact tggagagaca tcacaaggaa aaacaaaccg atgttgctgc    360

tgaagtcaag aacgatggta aaaatcagga cactgaagat gcactattaa ccgctgacag    420

tgcgcaaacc aaaaatttga aaagattttt tgatggtgcc aaagatgtta caggcagtcc    480

acctgcaaag cagcttaagg agatgccttc tgtttttcag aatgttctgg gcagcgctgt    540

cctctcacca gcacacaaag atactcanga tttccataaa aatgcagctg atgacagtgc    600

tgataaagtg aataaaaacc ctacccctgc ttacctggac ctgttaaaaa agagatcagc    660

agttgaaact caggcaaata aactcatctg aagaacaaag gcgatgttac tcctctccgg    720

atggcagtac cacccataac cttgaagtta gcccccaaga aaaacaaacg gaaaccggcg    780

ctgaatgcaa aaacggccca agggggattg tcccgaaaaa cctttaaatt ttcccggggg    840

ggtctttcaa tttgcccgaa atttttttga aaaaaaattt gtttccagaa acccgggccc    900

ttttgtactt caagaatttt tccccaaatt tttttggggc cccaaaaggg gagcaaaaaa    960

accccgcgga gcctaaaaaa gtggaaaaaa ccttttttaa aaaaccaaac ccgggtcccc   1020

cccattggtg ggaaaaaatg tccccccccc ctaattttaa aaccaacccc aatttttttc   1080

cccacaccaa aaaccctcac tcctaaagaa gaaaaaaccc tcttgccata cacccccccc   1140

cttttcttaa aacacttttt tttccccaan atccatttac ctacaaaaaa aaatgagtnc   1200

ttggttccca cccccacaca accataatat tcaataacac tccttcccac ctaacaaaaa   1260

aaccnatacc attctattaa tcactcntcc cacccactna ccaa                    1304


<210>  24
<211>  861
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (776)..(776)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (795)..(795)
<223>  n is a, c, g, or t

<400>  24
agagatacta tgagaggatc gcatcaccat caccatcacg gatcctattt aggtgacact     60

atagaatcgt cgactctgga ccttggctgt cactcagttc agccccaccg ctgcccatcc    120

tgtggggctg ccttcccctc ctcactgcgg ctccgggagc accgctgtgc agccgctgct    180

gcccaggccc cacggcgctt tgagtgtggc acctgtggca agaaagtggg ctcagctgct    240

cgactgcagg cacacgaggc ggcccatgca gctgctggac ctggagaggt cctggctaag    300

gagccccctg cccctcgagc cccacgggcc actcgtgcac cagttgcctc tccagcagcc    360

cttggaagca ctgctacagc atcccctgcg gcccctgccc gccgccgggg tctagagtgc    420

agcgagtgca agaagctgtt cagcacagag acgtcactgc aggtgcaccg gcgcatccac    480

acaggtgagc ggccatacca atgtccagac tgtggcaaag cgttccgtca gagtacccac    540

ctgaaagacc accggcgcct gcacacaggt gagcggccct ttgcctgtga agtgtgtggc    600

aaggcctttg ccatctccat gcgcctggca gaacatcgcc gcatccacac aggcgaacga    660

ccctactcct gccctgactg tggcaagagc taccgctcct tctccaacct ctggaagcac    720

cgcaagacca tcagcagcag catcaggcag ctgtgcggca gcagctggca aaggcngaag    780

ctgccgctgg cctgnccgtc atggaaactg ctgtggaagc gctacccctg gtggaagcac    840

ttgagatcta acctctggcc g                                              861


<210>  25
<211>  526
<212>  DNA
<213>  Homo sapiens

<400>  25
agagagatac tatgagaggt cgcatcacca tcaccatcac ggatcctatt taggtgacac     60

tatagaatcg tcgactctgg accttggctg tcactcagtt gagagtgtag ggctgctgac    120

aaatgaactg gccctggaga aggaggccac agagaagctg cggaagctcc tggcctccca    180

gagcagcggt ctccgagggc tgtgggactg cctgcccgca gacctagtgg gcgagaggag    240

tgcacaaagc aaagtagcgg agtccctgga ggagctgcgg gcctgcatca gcaccctggt    300

ggatcggcac cgggaggccc agcaggtgct ggctcggctg caagaagaga accagcagtt    360

gcgggggtcc ttgtccccgt gtagggagcc aggcacctcc ttaaaggccc cagcatcccc    420

ccaagtggcc gctctggagc aagacctggg gaagctggag gaagagctgc gggcagttca    480

ggccacgatg agcgggaaga gccaggagat cggaaagctg aagcag                   526


<210>  26
<211>  1503
<212>  DNA
<213>  Homo sapiens

<400>  26
cccccaaact aagaatacta gagaggatgc atcccatcac catcacggtc gacccacgcg     60

tccggccgcg ccgagggagg ggccggctcc agctccgggg cagcgcccgc cccgccccca    120

ggcccgcccc gcgctgaccg gctccgcgca ttggcccgcc ccgtgcgctg gcctgtcccg    180

cgcattggcc aagcggccgg gaggacgggc ccggcggccg tgcacttccg gccggtggcc    240

ggcccggcgc gcaccgcccc ttccgccgtc gcccagcgag cccagctccg gtcccagccc    300

cggccgtccc ggcgtcgctt cggagcgcgg cggcagctga ctgcgccttc acgatccgct    360

gggacccgcg agccccgccg ccgttatgaa catccgcaat gcgaggccag aggacctaat    420

gaacatgcag cactgcaacc tcctctgcct gcccgagaac taccagatga aatactactt    480

ctaccatggc ctttcctggc cccagctctc ttacattgct gaggacgaga atgggaagat    540

tgtggggtat gtcctggcca aaatggaaga ggacccagat gatgtgcccc atggacatat    600

cacctcattg gctgtgaagc gttcccaccg gcgcctcggt ctggctcaga aactgatgga    660

ccaggcctct ccagccatga tagagaactt cattgccaaa tatgtctccc tgcatgtcag    720

gaacagtaac cggaccgccc tgcacctcta ttccaacacc accatctttt cacatcaaag    780

aaacagcacc tccaacacca agccaattgg acaggccccc tattcacgaa accggcaccc    840

acctctaaag accccccagc ccaccctcca cctggtaccc gataaaaaac gccaccccta    900

ttcactgcac accaactcca cactcactca acatacaacc cctcccactc cctaactctc    960

atcaaccaca tcccaacctc tcaaacctcc accaccaccc acttctcact atccccacaa   1020

tcacccaccc accctcctca ccacaccatc tccaccctcc cccaccccac caatcccaca   1080

tctccatctc ccccacccca ccacccccca ttcccctcca ccccatttct tcccccaaac   1140

cctaccacac tccatcccca tccatcacaa tccacactct accccaccac cctcctccac   1200

cctctctact ccaacctcaa tcactaacac ctacacaccc caacaatccc acatcacgcc   1260

tcacaccaca ctcaaccact ctcacaactc atccccctaa aattccaaca cacccctcta   1320

tctactgcat cacctcactc acacttacca tactcctcac acacaaccct aaaccacaca   1380

taccacccta catctcaacc accgcatcac cattccgctt ccttccaacc acacaacaca   1440

cataccttct caactcacca cctccacact actcatacct ttacatccac ctcacacact   1500

acc                                                                 1503


<210>  27
<211>  2680
<212>  DNA
<213>  Homo sapiens

<400>  27
atgctgagcg gtgaacgtgt tctgcagacc gaacgtagcg ttgaaagcag cagcattagc     60

ctggttccgg gtacagatta tggcacccag gaaagcatta gtctgctgga agttagcacc    120

ctgggtaaag caaaaaccga accgaataaa tgtgttagcc agtgtgcagc atttgaaaat    180

ccgaaaggtc tgattcatgg ctgcagcaaa gataatcgta atgataccga aggctttaaa    240

tatccgctgg gtcatgaagt taaccatagc cgtgaaacca gcattgaaat ggaagaaagc    300

gaactggatg cacagtatct gcagaatacc tttaaagtta gcaaacgtca gagctttgca    360

ccgtttagca atccgggtaa tgccgaagaa gaatgcgcaa cctttagcgc acatagcggt    420

agcctgaaaa aacagagccc gaaagttacc tttgaatgcg aacagaaaga agaaaaccag    480

ggcaaaaacg aaagcaatat caaaccggtt cagaccgtta atattaccgc aggttttccg    540

gttgttggcc agaaagataa accggttgat aatgccaaat gcagcattaa aggtggtagc    600

cgtttttgtc tgagcagcca gtttcgtggt aatgaaaccg gtctgattac cccgaataaa    660

catggtctgc tgcagaatcc gtatcgtatt ccgcctctgt ttccgattaa aagctttgtt    720

aaaaccaaat gcaaaaaaaa tctgctggaa gaaaattttg aagaacattc catgagtccg    780

gaacgtgaaa tgggcaatga aaatattccg agcaccgtta gcaccattag ccgtaataat    840

attcgcgaaa atgtgtttaa agaagccagc agcagcaaca ttaatgaagt tggtagcagc    900

accaatgaag tgggtagctc aattaatgaa attggcagct ccgatgaaaa cattcaggca    960

gaactgggtc gtaatcgtgg tccgaaactg aatgcaatgc tgcgtctggg tgttctgcag   1020

ccggaagttt ataaacagag cctgcctggt agcaattgta aacatccgga aattaaaaaa   1080

caggaatatg aagaagttgt tcagacggtt aacaccgatt ttagcccgta tctgattagc   1140

gataatctgg aacagccgat gggtagcagc catgcaagcc aggtttgtag cgaaacaccg   1200

gatgatctgc tggatgatgg tgaaattaaa gaagatacca gctttgccga aaatgatatc   1260

aaagaaagca gcgcagtgtt tagcaaaagc gttcagaaag gtgaactgag ccgtagcccg   1320

agcccgttta cccataccca tctggcacag ggttatcgtc gtggtgcaaa aaaactggaa   1380

agcagcgaag aaaatctgtc aagcgaagat gaagaactgc cgtgttttca gcatctgctg   1440

tttggtaaag tgaataatat tccgtcacag agcacacgcc atagcaccgt tgcaaccgaa   1500

tgtctgagca aaaataccga agaaaacctg ctgagcctga aaaatagcct gaatgattgt   1560

agcaaccagg ttattctggc aaaagcaagc caggaacatc atctgagcga agaaaccaaa   1620

tgtagcgcaa gcctgtttag cagccagtgt agcgaactgg aagatctgac cgcaaatacc   1680

aatacccagg acccgtttct gattggtagc agtaaacaaa tgcgtcatca gagcgaaagc   1740

cagggtgttg gtctgagcga taaagaactg gttagtgatg atgaagaacg tggcaccggt   1800

ctggaagaaa acaatcaaga agaacagagc atggatagca atctgggtga agcagcaagc   1860

ggttgtgaaa gcgaaaccag cgttagcgaa gattgtagcg gtctgagcag tcagagcgat   1920

attctgacca cccagcagcg tgataccatg cagcataatc tgattaaact gcagcaggaa   1980

atggcagaac tggaagcagt tctggaacag catggttcac agccgagcaa tagctatccg   2040

agcattatta gcgatagcag cgctctggaa gatctgcgta atccggaaca gagcaccagc   2100

gaaaaagcag ttctgaccag ccagaaaagc agcgaatatc cgattagcca gaatccggaa   2160

ggtctgtcag cagataaatt tgaagttagc gcagatagca gcaccagcaa aaataaagaa   2220

ccgggtgttg aacgtagcag cccgagcaaa tgtccgagcc tggatgatcg ttggtatatg   2280

catagctgta gcggtagtct gcagaatcgt aattatccga gccaggaaga actgattaaa   2340

gttgttgatg tggaagaaca gcagctggaa gaaagtggtc cgcatgatct gaccgaaacc   2400

agctatctgc ctcgtcagga tctggaaggc accccgtatc tggaaagcgg tattagcctg   2460

tttagtgatg atccggaaag cgatccgagc gaagatcgtg caccggaaag cgcacgtgtt   2520

ggtaatattc cgagtagcac cagcgcactg aaagttccgc agctgaaagt tgcagaaagc   2580

gcacagagtc cggcagcagc acataccacc gataccgcag gttataatgc aatggaagaa   2640

tcagtgagcc gtgaaaaacc gtaagcggcc gcttaattaa                         2680


<210>  28
<211>  1305
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (818)..(818)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (892)..(892)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1216)..(1216)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1227)..(1227)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1261)..(1261)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1264)..(1264)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1274)..(1274)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1277)..(1279)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1284)..(1285)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1287)..(1287)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1289)..(1291)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1295)..(1296)
<223>  n is a, c, g, or t

<400>  28
nnaagccacc ccncctaaga atactagaga ggatgcatca ccatcaccat cacggtcgac     60

ccacgcgtcc ggtgcttgct gaggctgcac ttgctgacac tgcagctgcg acgcggctaa    120

gaggcgcaga gcgaggagtc gggatttggt cgcgagcggc gacggaagaa tatgaagaac    180

tgcttcgtta tgctatagtg actccaaata ttgaaccctg tgcttcacag tcatctcatc    240

ctaagggaga attggtgcca gatgtcagaa tttctacaat tcatgatatt cttcatagtc    300

aaggaaataa ctctgaagta agagaaactg caatagaagt tggaaaagga tgtgatttcc    360

atatttcaag tcattcaaag acagatgagt catcaccagt gttatcgcca aggaagcctt    420

ctcacccagt catggatttt ttcagttcac atcttttagc tgactcttcc tcaccagcaa    480

caaattctag tcatacagat gcccatgaaa tacttgtgag cgattttctt gtttctgatg    540

aaaaccttca gaagatggaa aatgtgcttg atctttggag ttcaggtctt aagacaaaca    600

tcatatctga actaagtaaa tggagactta attttattga ctggcaccga atggaaatga    660

gaaaagagaa agaaaaacat gcagcacatt taaaacaact gtgtaatcag atcaatgaat    720

tgaaggagct gcaaaaaacc tttgaaatct ccattgggag aaaagatgaa gggatttcta    780

gcttgtctca tgccataagc aagcaaaagg aaagatanag ttgatgagaa cattcttcca    840

ctggcgaatc ggccatgtca gagcagacag gatgtttatg aaagtaaact anctgaccag    900

tactaccaga gaactttact gaagaaagtc tggaaaggct gggggttccg taaggcaaag    960

caaggggaaa gatggggtaa aaaaaacttg gcaagcaaag actgaaaaaa attgaatcca   1020

aattcccagg attagaagcc caggtggcta ggtttcgggg ctttggaaat ggcaaaactg   1080

aattcaaaaa ggcacatgga aaggcccctt tgagatccct aaaaaacttc tggagggggg   1140

gggcttaatc ttgagcctgc aattttcaac aaaatggggg gataacccca aaaataaaag   1200

aaaaatgtcc tggttnaaaa aaaaatnttc ttttactccc cccccaaccc taaaaaaaac   1260

ngtnctccca cccnccnnna gaannanann ntccnntttt aattt                   1305


<210>  29
<211>  613
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (5)..(5)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (16)..(16)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (18)..(18)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (20)..(20)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (23)..(23)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (26)..(28)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (78)..(78)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (82)..(82)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (540)..(540)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (613)..(613)
<223>  n is a, c, g, or t

<400>  29
tttcntttgt ngcggnanan tantannnga ttaattgtag cggatacaat ttacacagaa     60

ttattaagag gagaaatnac tntgagagga tcgcatacca tcaccatcac ggatcctatt    120

taggtgacac tatagaatcg tcgacccacg cgtccggatc actgcgacca gaggaaattg    180

aagagctccg agaggccttc agagaattcg acaaggacaa ggatggctac atcaactgcc    240

gggatctggg caactgcatg cgcaccatgg gctacatgcc caccgagatg gagctcatcg    300

aactgtccca gcagatcaac atgaacctgg gtggccatgt agattttgat gacttcgtgg    360

agctaatggg gcctaaactc ctggcagaga cagcagatat gattggtgta aaggaactgc    420

gagatgcttt ccgagagttt gacaccaatg gtgatgggga aataagcacc agtgagctgc    480

gagaggctat gaggaagctc ctgggtcatc aggtgggaca ccgagacata gaggaaattn    540

tccgggatgt ggacctcaat ggggatggac gagtggactt ttgaagagtt tgtccggatg    600

atgtcccgct gan                                                       613


<210>  30
<211>  638
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (607)..(608)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (615)..(615)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (617)..(617)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (619)..(619)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (621)..(621)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (623)..(623)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (625)..(625)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (629)..(638)
<223>  n is a, c, g, or t

<400>  30
tngnggnaat tactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg gtgccatcct gcccgcactg aagcagaccc    120

cgaaggaagc tagctttccc agggaccaag aagccacgca tttccccaag gtctccacca    180

agagcctctc caagaaatgc ctgagcccac ctgtggcgga gcgtgccatc ctgcccgcac    240

tgaagcagac cccgaagaac aactttgccg agaggcagaa gaggctgcag gcaatgcaga    300

aacggcgcct gcatcgctca gtgctttgag ccaccccaat ctggtcagtg ccaggcccac    360

caacctgcag ctggagactg gctctctata gcatttcctg atacttccgc tacttttagg    420

cctggctaaa ttccaagaca gataacactc aagatagata aagtacttga tctccaaact    480

gacaaactgt ttattttcta gctgttattt tgctatttgg catttacgta aaagcacacg    540

atgaagcagg tatcgcctta cctgttgaaa ctgaaaataa agcttgttta tttccaaaaa    600

aaaaaannaa aaaananana nananaaann nnnnnnnn                            638


<210>  31
<211>  1181
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (828)..(828)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (889)..(889)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (910)..(910)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (943)..(943)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (949)..(949)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (963)..(963)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (975)..(975)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (981)..(981)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (990)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1007)..(1007)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1019)..(1019)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1033)..(1033)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1044)..(1044)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1048)..(1049)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1066)..(1066)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1079)..(1079)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1081)..(1081)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1088)..(1088)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1097)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1115)..(1116)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1123)..(1123)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1133)..(1134)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1136)..(1137)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1140)..(1141)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1151)..(1153)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1174)..(1175)
<223>  n is a, c, g, or t

<400>  31
nnaatagaga aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgcgcgacg ccgcgctggt tggtgctcct    120

gcgccggagg agttctgcgt ctcggggtgg tgactgggtc cagaatggct tcggattcgg    180

ggaaccaggg gaccctctgc acgttggagt tcgcggtgca gatgacctgt cagagctgtg    240

tggacgcggt gcgcaaatcc ctgcaagggg tggcaggtgt ccaggatgtg gaggtgcact    300

tggaggacca gatggtcttg gtacacacca ctctacccag ccaggaggtg caggctctcc    360

tggaaggcac ggggcggcag gcggtactca agggcatggg cagcggccag ttgcagaatc    420

tgggggcagc agtggccatc ctgggggggc ctggcaccgt gcagggggtg gtgcgcttcc    480

tacagctgac ccctgagcgc tgcctcatcg agggaactat tgacggcctg gagcctgggc    540

tgcatggact ccacgtccat cagtacgggg accttacaaa caactgcaac agctgtggga    600

atcactttaa ccctgatgga gcatctcatg ggggccccca ggactctgac cggcaccgcg    660

gagacctggg caatgtccgt gctgatgctg acggccgcgc catcttcaga atggaggatg    720

agcagctgaa ggtgtgggat gtgattggcc gcagcctgat tattgatgag ggagaagatg    780

acctgggccg gggaggccat cccttatcca agatcacagg gaactccngg ggaaaaggtt    840

ggcctgtggc atcattgcac gctccgctgg ccttttccaa aaccccaanc aaatctgctc    900

ttgcgatggn cctcaccatc tgggaagaaa cgaagccggc ccnatcccnt ggcaaagggc    960

ccnaaagaaa ttcancaaaa ncccccttgn cccacttttt naacagnacc tcccccttng   1020

gctctgttgc tgncctccaa gggnaaannc ttttccactt ccaaangggn ccaaaaggna   1080

ntttgccntg ccccannctt ttgnaaaact tcaannaaaa ggncaagaac ttnntnnggn   1140

ntttcccttt nnnaaaaaaa aaatttttat tttnnttttg g                       1181


<210>  32
<211>  540
<212>  DNA
<213>  Homo sapiens

<400>  32
atggatattg caattcatca tccgtggatt cgtcgtccgt tttttccgtt tcatagcccg     60

agccgtctgt ttgatcagtt ttttggtgaa catctgctgg aaagcgacct gtttccgacc    120

agcaccagcc tgagcccgtt ttatctgcgt ccgcctagct ttctgcgtgc accgagctgg    180

tttgataccg gtctgagcga aatgcgtctg gaaaaagatc gttttagcgt taacctggac    240

gtgaaacatt tttcaccgga agaactgaaa gtgaaagttc tgggtgatgt gattgaagtg    300

catggtaaac atgaagaacg ccaggatgaa catggtttta ttagccgtga atttcaccgc    360

aaatatcgta ttccggcaga tgttgatccg ctgaccatta ccagcagcct gagcagtgat    420

ggtgttctga ccgttaatgg tccgcgtaaa caggttagcg gtccggaacg taccattccg    480

attacccgtg aagaaaaacc ggcagttacc gcagcaccga aaaaataagc ggccgcttga    540


<210>  33
<211>  1453
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (786)..(786)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (851)..(851)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (866)..(866)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (875)..(876)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (949)..(949)
<223>  n is a, c, g, or t

<400>  33
nccccctgag agatacttga gaggatcgca tcaccatcac catcacggtc gacccacgcg     60

tccggcgctg agtcgagctg ggcaggagat gagcctagcg gccctgaagc aacacgaccc    120

ctatatcacc agcatcgcag acctcacggg ccaggtcgct ctgtacacct tctgccccaa    180

ggccaaccag tgggagaaga ctgatataga agggacctta ttcgtatatc gaaggtcagc    240

ttccccttac catggtttta ccattgtgaa tcgactaaat atgcacaatc tagttgaacc    300

agtgaataaa gatttggaat ttcagctcca tgaaccattt cttctgtata gaaatgcaag    360

cttgtcgata tatagtatct ggttttatga caagaatgac tgtcaccgca tagcaaaact    420

catggctgat gtggtagaag aggagacacg gcgatcccag caagctgctc gggacaaaca    480

gagtcccagc caggccaatg gctgcagcga ccacaggccc atcgacatcc tggagatgct    540

gagcagagcc aaggatgagt atgagaggaa tcagatgggt gactcaaata tctccagccc    600

tgggttacag ccaagcactc agctctccaa tctgggaagc accgagactc tagaagaaat    660

gccctccggg tcacaggata agtctgctcc atctggacac aagcatctga cggtagaaga    720

gttatttgga acctctttgc caaaggaaca acagcaagtt gtgggtctgg attcagaaga    780

aatggnagag ttgccaggag atgcctccca gaaagagccc aatccaattc taccatttcc    840

ctttgagcag ntaagaggag cccctncatc agaannccct gggtgtccct tctgctgccc    900

accaattcag tccagctgga atcacccccc ccggggctaa tcactcaanc ctccattaca    960

cagtccaatg aaaaagatgc tccaacctac ccaatccggt tgagccctgt tcccatccca   1020

ctctgccagc tgaaattcca tatgcacagg ttcccccagc ttacctcaac aggcccatga   1080

ttgccgcgtg aaaacccccc taaagaagtc tccctcctga acagccaatc ctgcactaac   1140

ctggccactt gatgccacca aaccccttgg gccccatgaa aacaaaacac gtggcaatcc   1200

cccacctttt tttctccaaa tcggtgcccc cacttccaat cataacacac ctcgaggggc   1260

agggccccct ctcctgccgc tgtgaaccac cgtccatcta ccctcctcac aacccaccag   1320

ggccccctcc taaatagtgc tccccctgct acacacactc tttccatcgt tcattcgtga   1380

cccatcaacc aacatcattc ccgtctcact ctccactcac acaccttctc cacacctact   1440

ctcctactcc act                                                      1453


<210>  34
<211>  1328
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (952)..(952)
<223>  n is a, c, g, or t

<400>  34
gagccggccc taagaatact atagaggatg catcccatca ccatcacggt cgacccacgc     60

gtccgacgcg ctgcttcgga accgtggtgg gcgacacgcc cgcctacctc tacgaggagc    120

gctggacgcc cccctgctgc ctgcgcgcgc tgcgcgagac cgcccgctat gtggtgggcg    180

tgctggaggc tgcgggcgtg cgctactggc tcgagggcgg ctcactgctg ggggccgccc    240

gccacgggga catcatccca tgggactacg acgtggacct gggcatctac ttggaggacg    300

tgggcaactg cgagcagctg cggggggcag aggccggctc ggtggtggat gagcgcggct    360

tcgtatggga gaaggcggtc gagggcgact ttttccgcgt gcagtacagc gaaagcaacc    420

acttgcacgt ggacctgtgg cccttctacc cccgcaatgg cgtcatgacc aaggacacgt    480

ggctggacca ccggcaggat gtggagtttc ccgagcactt cctgcagccg ctggtgcccc    540

tgccctttgc cggcttcgtg gcgcaggcgc ctaacaacta cccccgcttc ctggagctca    600

agttcgggcc cggggtcatc gagaaccccc agtaccccaa cccggcactg ctgagtctga    660

cgggaagcgg ctgaagccct gataacctcg cctttgtttt tccggggtct ggctggatga    720

agaaaaacct ccgctgaccg atgatactag taaggagatc tccccaaagc aaccgagaaa    780

ctccccatca tacaacttct tacgacaact tacaaactcg ccccatcttc cccaaaaact    840

cacctacacc acaccctaaa ccaccacctg tacttttcaa cgcactgcac accagtatcc    900

ctgactcttc ttccaaccta cctccatctc ctcccttcaa ctacaaacca cnaacatcct    960

cccaccacca aaacccacca ccccaacacc cacactacac ccctagcccc tactccacac   1020

cacacaccca ccaccacata actacctcac acatctccct ctcccactca atcacatcct   1080

acaacactcc cacatcattc aaccctccat tccacatttc actcccacca tccccttccc   1140

ctcctctacc acacatcccc tccccttccc ccccatcctt ctcaacagac ctatctatac   1200

cccacgacac actcctcacc ctcacacatc tcccatacat cctctcatcc tacccatcca   1260

ccttcacttc cacctactcc aacatctcat ccactccctc aatactccac cacactaccc   1320

cccatctc                                                            1328


<210>  35
<211>  1186
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (866)..(866)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (947)..(947)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (978)..(978)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (985)..(985)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (996)..(996)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1030)..(1030)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1042)..(1042)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1047)..(1047)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1052)..(1052)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1055)..(1055)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1083)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1107)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1120)..(1120)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1124)..(1124)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1138)..(1138)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1140)..(1140)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1150)..(1150)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1152)..(1153)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1176)..(1178)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1186)..(1186)
<223>  n is a, c, g, or t

<400>  35
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc aaacattgag gaaagccagg cagtagaggc    120

cgctatggcg aacgttccgt gggcagaggt ctgcgagaaa ttccaggcgg cgctcgctct    180

gtcgcgggtg gaactgcata aaaatccgga gaaggaacca tacaagtcca aatacagcgc    240

ccgggcgcta ctggaagagg tcaaggcgct gctcggccct gcgcctgagg acgaggatga    300

gcggcctgag gccgaggaca gcccgggtgc cggtgaccac gccctggggc tgccggctga    360

ggtggtggag cccgaggggc ccgtcgccca gcgagcggtg aggctggcag tcatcgagtt    420

ccacctcggg gtgaaccaca tcgacacgga ggagctgtcg gcgggggagg agcacctggt    480

gaaatgcctg cggctgctgc gcaggtaccg gctctcgcac gactgcatct ctctctgcat    540

ccaggcgcag aataacctgg gtatcttgtg gtctgaaaga gaagaaattg aaactgcaca    600

ggcttaccta gagtcatcag aagcactata taatcagtat atgaaagagg ttgggagtcc    660

tcctcttgat cctactgagc gttttcttcc tgaagaagag aaacttactg aacaagagag    720

atcaaaaaga tttgaaaagg tttatactca taacctatat tacctagctc aagtctacca    780

gcatctggaa atgtttgaga aggctgctca ctattgccat agtacactaa aacgccagct    840

tgagcacaat gcctaccatc ctatanagtg ggctatcaat gctgctacct tgtcacagtt    900

ttacatcaat aagctatgct ttatggaggc caggcactgt ttatcanctg ctaatgtcat    960

ttttggtcaa ctggaaanat ctcanccaca aaaaanactc ctgaaactga aggaaaattn   1020

ccaaactttn tcttcaaaaa anggggnaat ancanggtgc tgaatcaaan actgtttgat   1080

tnnatgcaaa atgccnantt tccntnnagn aaaaataagn aaantttgat tttaaaanan   1140

tttgaatttn anntttttgg gaaaaaaaac tttttnnngg ggaaan                  1186


<210>  36
<211>  1328
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (891)..(891)
<223>  n is a, c, g, or t

<400>  36
tcgacttacc tataaaaggc gtatcacgag gccctttcgt cttcacctcg agaaatcata     60

aaaaatttat ttgctttgtg agcggataac aattataata gattcaattg tgagcggata    120

acaatttcac acagaattca ttaaagagga gaaattaact atgagaggat cgcatcacca    180

tcaccatcac ggtcgaccca cgcgtccgcc ggaaatgagg gttgagccac agccgaggat    240

gtgggtgccg gagagccctg tgtgtaggtc gggaagaggt gagagtaagt ctgagagctg    300

gagtgaggag ctgcagcctg gccacccacg tgcctggcct ccatccccgg gccgctttcg    360

cgtggaagaa ggtggcggtg cacctttctg ctcagcagat ggaagcacga gtgcagagaa    420

gagacacctg gaggttagca acggaatgga cgagctggca ggtagcccat ttcctgtgac    480

gagaatgtct tcaagatcaa gtgacgcaaa accactgccc gcgtcctatc cagctgaacc    540

tagggagccc caggaaactc cgaaaatcac cagtgctttc agctctgtga aaccaagtga    600

agcggtccct cggaagtttg acagtggtgg agagaggggg gcagggctcc cactgtccct    660

gtctaacaag aaccgagggc tctcagctcc agacttacgg tctgtggggc tcacccctgg    720

gcaagaacag ggtgccagtg agctagaggg gtctttgggt gaagcaagca caatagaaat    780

ccccccacgg ccgcgatccg catgcgagct cgattagctg agcttggact cctgttgata    840

gatccagtaa tgacctcaga actccatctg gatttgttca aaacgctcgg ntgccgccgg    900

cgttttttta ttggtgagaa tccaagctag cttggcgaga ttttcaggag ctaaggaagc    960

taaaatgaag aaaaaatcac tggatatcca ccgttgatat atcccaatgc catcgtaaag   1020

aacatttgag gcatttcagt catttgctca tgtaccttta ccagaacggt cactggatat   1080

tcgggctttt taaaaccgta aaaaaaataa cccaatttta tcggccttta ttcctttttg   1140

gcgcccgaag aaggtctccg aatttcaatg gaaagaaaaa gggactggga ataggaaaag   1200

ttcacccttt taaccgcttc tttaaaaaat gaaatttctt tcttctggag aaaaaaaaca   1260

atttcgagat tctccatatt ctcagaagtg gggtacggaa acacgctttt tccaaaggta   1320

tataaaat                                                            1328


<210>  37
<211>  1311
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (8)..(13)
<223>  n is a, c, g, or t

<400>  37
nagaacannn nnngcaatat actgacttac ctataaatag gcgtatcacg aggccctttc     60

gtcttcacct cgagaaatca taaaaaattt atttgctttg tgagcggata acaattataa    120

tagattcaat tgtgagcgga taacaatttc acacagaatt cattaaagag gagaaattaa    180

ctatgagagg atcgcatcac catcaccatc acggtcgacc cacgcgtccg cccacgcgtc    240

cgcagcatac agtcatgaag cttccatggg acagtcttct gaccaggtgt ttggaaaaat    300

tacagcctgc ctatcaagtg acccttcccg gacaagagcc cattgtgaag aaagggagaa    360

tctgtccaat tgacatcacc ctagcacaaa gagcgtctaa taaaaagtcc ccccaggtga    420

ccgtggtccg gaacttggag gcctatggtc tggacccata ctcagtggct gccatccttc    480

agcagcgatg ccaggctagc accaccgtca atcctgcccc tggggccaag gacagccttc    540

aggtgcagat ccagggaaac caggtccacc acctcggctg gctattgctt gaagagtatc    600

agctccctcg aaaacacatc caaggtctag aaaaggccct caaacccggc cgcgatccgc    660

atgcgagctc gattagctga gcttggactc ctgttgatag atccagtaat gacctcagaa    720

ctccatctgg atttgttcag aacgctcggt tgccgccggg cgttttttat tggtgagaat    780

ccaagctagc ttggcgagat tttcaggagc taaggaagct aaaatggaga aaaaatcact    840

ggatatacac cgttgatata tcccaatggc atcgtaaaga acattttgag gcatttcagt    900

cagttgctca atgtacctat aaccagaccg ttcagctgga tattacggcc cttttaaaga    960

cccgtaagaa aaataagcca agttttatcc ggcctttatt tccatccttg ccgcctggat   1020

gaagctcatc cggaattcca aggccaagaa aaacggtgac cgggggaaag ggaaaagggt   1080

ccccctgtta cacggttttc ctgaaccact ggaaagtttt ctccctccgg aggaaaaccc   1140

aaaaatttcc gggagtttca caaaatttcc caaaaatggg ggttacggga aaactggcct   1200

atttcctaag ggttttggaa aattttttcc cctccccacc ccggggggtt ccccatttat   1260

ttaacagggc caaaggaaac tttccccccg tttcccgggg gaatatacac g            1311


<210>  38
<211>  885
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (513)..(513)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (544)..(544)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (551)..(551)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (556)..(556)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (565)..(565)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (582)..(582)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (613)..(613)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (619)..(619)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (655)..(655)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (669)..(669)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (675)..(675)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (681)..(681)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (685)..(685)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (699)..(699)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (701)..(701)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (718)..(718)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (721)..(721)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (723)..(723)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (727)..(727)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (736)..(736)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (744)..(744)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (750)..(750)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (766)..(766)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (779)..(780)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (815)..(815)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (825)..(825)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (831)..(831)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (834)..(834)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (838)..(839)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (845)..(845)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (850)..(850)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (852)..(852)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (879)..(879)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (881)..(881)
<223>  n is a, c, g, or t

<400>  38
cttaagagga gaattaacta tgagaggatc gcatcaccat caccatcacg gatcctattt     60

aggtgacact atagaatcgt cgacccacgc gtccgaaagc ttacggagta agtggaaaag    120

aaagatgcgt gctgaaaaga gaaaaaagaa tgccccaaag gaggccagca ggcttaaaag    180

tattctcaaa ctagacggtg atgttttaat gaaagatgtt caagagatag caactgtggt    240

ggtacccaaa cccaaacatt gccaagagaa aatgcaatgt gaggtaaaag atgaaaaaga    300

tgacatgaaa atggagactg atattaagag aaacaaaaag actcttctag accagcatgg    360

acagtaccca atatggatga accaaaggca aagaaaaagg ctgaaggcaa agcgagagaa    420

aagaaagggg aaaagcaaag caaaagcagt gaaagtggca aagggtttgg cctggtagac    480

tcttaaaacc ttggaaaatg ccacatggaa tanatgacgg gattagaatg tatacccatg    540

taanttttga nttcanctgc caccnaaatg aaaaccattg gntttcctat tttaacttgg    600

cctttttttc ctnaattcna aacccagcat aactcctcaa gtttgttttt ggaancttga    660

aaaaaaaant tttcntttga naacncccag gcccccacng naacttttta accgggangc    720

nancccnata ttcccngtta taantcaggn cccccaaccg ttttgnccag ggaattaann    780

tggggtaaaa atttgtctct taccaccggg gaaantttta gcccnaaaag ngtnaaannc    840

cgatnggggn gnttggccaa attttttggg ggacctttna ntttt                    885


<210>  39
<211>  1179
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (3)..(5)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (8)..(10)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (17)..(18)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (22)..(23)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (28)..(28)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (38)..(38)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (42)..(43)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (58)..(58)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (72)..(72)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (113)..(113)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (838)..(838)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (870)..(870)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (959)..(959)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1000)..(1000)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1004)..(1004)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1036)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1055)..(1055)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1058)..(1058)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1060)..(1060)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1065)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1068)..(1068)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1079)..(1079)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1082)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1090)..(1091)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1095)..(1095)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1108)..(1108)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1111)..(1111)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1124)..(1124)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1139)..(1140)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1142)..(1143)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1152)..(1152)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1154)..(1154)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1157)..(1157)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1165)..(1165)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1177)..(1177)
<223>  n is a, c, g, or t

<400>  39
gannnggnnn ttncggnnag annattgnat caccatcncc annacggatc ctatttangt     60

gacagctata gnatcgtcga cccacgcgtc cgggaaagct ctggctttca ggntagagga    120

agagcagaag atgaggccag aaattgctgg gttaaaacca gcaaatccac ccgtcttacc    180

agctcctcag aaggcggaca ccgaccctga gaacttacct gagatttcgt cacagaagac    240

acaaagacac atccagcggg gaccacctca cctgcagatt agacccccaa gccaagacct    300

gaaggatggg acccaggagg aggccacaaa aaggcaagaa gcccctgtgg atccccgccc    360

ggaaggagat ccgcagagga cagtcatcag ctggagggga gcggtgatcg agcctgagca    420

gggcaccgag ctcccttcaa gaagagcaga agtgcccacc aagcctcccc tgccaccggc    480

caggacacag ggcacaccag tgcatctgaa ctatcgccag aagggcgtga ttgacgtctt    540

cctgcatgca tggaaaggat accgcaagtt tgcatggggc catgacgagc tgaagcctgt    600

gtccaggtcc ttcagtgagt ggtttggcct cggtctcaca ctgatcgacg cgctggacac    660

catgtggatc ttgggtctga ggaaagaatt tgaggaagcc aggaagtggg tgtcgaagaa    720

gttacacttt gaaaaggacg tggacgtcaa cctgtttgag agcacgatcc gcatcctggg    780

ggggctcctg agtgcctacc acctgtctgg ggacagcctc ttcctgagga aagctganga    840

ttttggaaat cggctaatgc ctgccttcan aacaccatcc aagattcctt actcggatgt    900

gaacatcggt actggagttg cccacccgcc acggtggacc tccgacagca ctgtggccna    960

agaggcattg gaaaaggtga acancacatc ccggcctgtn tggnaaaaag atgggctggt   1020

gcccatgttc atcaanaccc acagtggcct cttcnccncn tgggngtntt cccctgggnc   1080

cngggccaan nctanttgat aactgctnaa ncatgattcc gggngggaaa cagaaaaann   1140

tnntggaaaa ancntgnaac ccttnagggt ttaaaancc                          1179


<210>  40
<211>  1302
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (935)..(935)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (958)..(958)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (971)..(971)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (975)..(975)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (996)..(996)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1011)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1019)..(1019)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1030)..(1030)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1043)..(1043)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1049)..(1049)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1052)..(1052)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1082)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1100)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1103)..(1103)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1123)..(1123)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1147)..(1147)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1149)..(1149)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1167)..(1168)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1172)..(1172)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1176)..(1176)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1182)..(1182)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1187)..(1187)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1193)..(1193)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1200)..(1200)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1223)..(1223)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1225)..(1225)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1228)..(1228)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1231)..(1231)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1233)..(1233)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1237)..(1237)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1260)..(1261)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1265)..(1265)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1282)..(1282)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1289)..(1289)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1302)..(1302)
<223>  n is a, c, g, or t

<400>  40
naantagaga aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgtatgccc tatgtctgta gatcaaaagg    120

acactacgcc ttattctagc aaattactaa aatcatgtct tgaaacagtt gcctccaacc    180

caggaatgcc tgtgaagtgt ctaacttcta atttactcca gtctaggaaa aggctggcca    240

catccagtgc cagtagtcaa tcccacacct tcatatccag tgtggaatca gaatgccaca    300

gcagtcccaa atgggaaaaa gattgccagg aaagtgatga agcattgggc ccaacaatga    360

tgagttggaa tgcagttgaa aagttatgcg caaaatctgc aaatgccatt gagacgaaag    420

gtttcaataa aaaggatctg gagttagctc tttctcccat tcataacagc agtgcccttc    480

ccaccactgg acgctcttgt gtaaaccttg ctaaaaaatg cttctctggg gaagtttctt    540

gggaagcagt agaactggat gtaaataata taaatatgga cactgacaca agtcagttag    600

gtttccatca gtcaaatcag tgggctgtgg attctggtgg gatatctgaa gagcaccttg    660

ggaaaagaag tttaaaaaga aattttgagt tggttgactc cagtccttgt aaaaaaatta    720

tacagaataa aaaaacttgt gtagagtata agcataacga aatgacaaat tgttatacaa    780

atcaaaatac aggcttaaca gttgaagtgc aggaccttaa gctatcagtg cacaaaagtc    840

aacaaaatga ctgtgctaat aaaggagaac attgtcaatt cttttactga taaacaacaa    900

acacccagaa aaattaccta taccaatgga tagcnaaaaa accttatgtg tgaactcnat    960

gaaaactggg naaanaatag taagagggac tacttnaagt tctagttttc naatgttcng   1020

aagaagaaan agcttnnnaa aanaatttnt angaactcng attcctcctt ttccgggaat   1080

tnctaaaaag ggaaantccn ntnaaaaagt ccccccctta aanttcaaaa aaaaacttta   1140

aaaaatncnc ctttttgaaa aacaaanntg gnaaanccct tnttggnacc ccnaatgccn   1200

aaaaaaaccc cccccaaagg ggncnaancc ngncttnaaa aaaaaaccaa aaaaggtggn   1260

ncccnttggg gggggggaaa cnttacccna aaaaaggggg gn                      1302


<210>  41
<211>  1087
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (880)..(880)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (909)..(909)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (920)..(920)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (948)..(948)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (967)..(967)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (990)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(998)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1018)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1023)..(1023)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1025)..(1025)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1036)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1044)..(1044)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1047)..(1047)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1050)..(1050)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1053)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1064)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1067)..(1067)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1073)..(1073)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1075)..(1076)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1080)..(1080)
<223>  n is a, c, g, or t

<400>  41
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccga gagtcctcgc gtggtctcct gcctcgagca    120

cagcctgtgc ccaggggagc cgggcttgca gacaacagca gtggtgtcca tgggctctgg    180

agaccatcag ttcaacctcg cagagatcct gtcacagaac tacagtgtta ggggggagtg    240

cgaggaggcc tcgaggtgcc cagacaagcc caaggaggag ctggagaagg acttcatctc    300

ccagagcaac gacatgccct ttgatgagct gcttgcgctc tatggctacg aggcgtcaga    360

ccccatttca gaccgggaga gtgagggtgg tgacgtggcc ccgaacctcc cagacatgac    420

cctggacaaa gaacaaatag cgaaggattt gctttcaggg gaagaagagg aagagacgca    480

atcatctgct gacgacctca ccccgtccgt gacctcccac gaggcctccg acctcttccc    540

taaccggagt ggatctcgtt tcctggctga tgaagacaga gagcctggct cttctgcctc    600

ctccgacacc gaggaggact ctcttcctgc caacaaatgt aagaaggaga tcatggtggg    660

acctcagttc caagctgacc tcagcaacct gcacttgaac cggcactgtg agaagatcta    720

cgagaacgaa gaccagctgc tctgggaccc cagcgtcctc cctgagaggg aggtggagga    780

gttcctgtac agggcggtga agcggcgttg gcacgagatg gccgggcctc agctcccaga    840

gggagaagcc gtgaaagaca gtgagcaggc gctgtacgan ttggtgaatg caacttcaat    900

gtggaggang ccctgcgaan gctgcggttc acgtgaaggt gatccganat gggctctgtg    960

cttggantga aaaagaatgc angaactttn aacacgnntc cgtgtgcatg gaaaaaantt   1020

tcncntgatc caggcnaaca aggngcnccn acnggtcant gggnnantgn ttnannactn   1080

tacctgt                                                             1087


<210>  42
<211>  2269
<212>  DNA
<213>  Homo sapiens

<400>  42
atgctgcgtg caaaaaatca gctgtttctg ctgtctccgc attatctgcg tcaggttaaa     60

gaaagcagcg gtagccgtct gattcagcag cgtctgctgc accaacaaca gccactgcat    120

ccggaatggg cagcactggc aaaaaaacag ctgaaaggca aaaatccgga agatctgatt    180

tggcatacac cggaaggtat tagcattaaa ccgctgtata gcaaacgtga taccatggat    240

ctgccggaag aactgcctgg tgttaaaccg tttacccgtg gtccgtatcc gaccatgtat    300

acctttcgtc cgtggaccat tcgtcagtat gcaggtttta gcaccgtgga agagagcaac    360

aaattctata aagataacat taaagcaggt cagcagggtc tgagcgttgc atttgatctg    420

gcaacccatc gtggttatga tagcgataat ccgcgtgttc gtggtgatgt tggtatggca    480

ggcgttgcaa ttgataccgt ggaagatacc aaaattctgt ttgatggcat cccgctggaa    540

aaaatgagcg ttagcatgac catgaatggt gcagttattc cggttctggc caattttatt    600

gttaccggtg aagaacaggg tgttccgaaa gaaaaactga ccggcaccat tcagaatgat    660

attctgaaag aatttatggt gcgcaacacc tatatttttc cgcctgaacc gagcatgaaa    720

attatcgccg atatcttcga atataccgcc aaacatatgc cgaaattcaa cagcattagc    780

atcagcggtt atcatatgca ggaagcaggc gcagacgcaa ttctggaact ggcatatacc    840

ctggcagatg gtctggaata tagccgtacc ggtctgcagg caggtctgac cattgatgaa    900

tttgcaccgc gtctgagctt tttttggggc atcggcatga acttttacat ggaaattgca    960

aaaatgcgtg caggtcgtcg tctgtgggca catctgatcg aaaaaatgtt ccagccgaaa   1020

aatagcaaaa gcctgctgct gcgtgctcat tgtcagacca gcggttggag cctgaccgaa   1080

caggacccgt ataataacat tgtgcgtacc gcaattgaag caatggcagc agtttttggt   1140

ggcacccaga gcctgcatac caatagcttt gatgaagcac tgggtctgcc gaccgttaaa   1200

agcgcacgta ttgcacgtaa cacccagatt attattcagg aagaaagcgg tattccgaaa   1260

gttgcagatc cgtggggtgg tagctatatg atggaatgcc tgaccaatga tgtttatgat   1320

gcagccctga aactgattaa cgaaatcgaa gaaatgggtg gtatggcaaa agcagttgca   1380

gaaggcattc cgaaactgcg tattgaagaa tgtgcagcac gtcgtcaggc acgtattgat   1440

agcggtagcg aagttattgt gggcgtgaac aaatatcagc tggaaaaaga agatgcagtt   1500

gaagttctgg caattgataa taccagcgtg cgtaatcgcc agatcgagaa actgaaaaaa   1560

atcaaaagca gccgtgatca ggcactggca gaacattgtc tggcagcact gaccgaatgt   1620

gcagccagcg gtgatggtaa tattctggca ctggcagttg atgcaagccg tgcacgttgt   1680

accgttggtg aaattaccga tgccctgaaa aaagtgtttg gcgaacacaa agccaatgat   1740

cgtatggtta gcggtgcata tcgtcaggaa tttggcgaaa gcaaagaaat taccagcgcc   1800

attaaacgcg tgcataaatt tatggaacgt gaaggtcgcc gtccgcgtct gctggttgca   1860

aaaatgggtc aggatggtca tgatcgtggt gcaaaagtta ttgcaaccgg ttttgcagat   1920

ctgggttttg atgttgatat tggtccgctg tttcagacac cgcgtgaagt tgcacagcag   1980

gccgttgatg cagatgttca tgcagttggt gttagcaccc tggcagcagg tcataaaacc   2040

ctggttccgg aactgattaa agaactgaat agcctgggtc gtccggatat tctggttatg   2100

tgtggtggtg ttattccgcc tcaggattat gaatttctgt ttgaagtggg cgttagcaat   2160

gtttttggtc cgggtacacg cattccgaaa gcagcagttc aggttctgga tgatatcgag   2220

aaatgcctgg aaaaaaaaca acagagcgtg taagcggccg cttaattaa               2269


<210>  43
<211>  960
<212>  DNA
<213>  Homo sapiens

<400>  43
gagaggtcgc atcaccatca ccatcacgga tcctatttag gtgacactat agaatcgtcg     60

acccacgcgt ccgagaagcg ggagctggag ggcaagctcg ccaccctcag cgaccaggtg    120

aaccggcggg actttgagtc agagaagcgg ctgcggaagg acctgaagcg caccaaggcc    180

ctgctggcag atgcccagct catgctggac cacctgaaga acagtgctcc cagcaagcga    240

gagattgccc agctcaagaa ccagctggag gagtcagagt tcacctgtgc ggcagccgtg    300

aaagcacgga aagcaatgga ggtggagatc gaagacctgc acctgcagat tgatgacatc    360

gccaaagcca agacagcgct ggaggagcag ctgagccgcc ttcagcgtga gaagaatgag    420

atccagaacc ggctggagga agatcaggaa gacatgaacg aattgatgaa gaagcacaag    480

gctgccgtgg ctcaggcttc ccgggacctg gctcagataa atgatctcca agctcagcta    540

gaagaagcca acaaagagaa gcaggagctg caggagaagc tacaagccct ccagagccag    600

gtggagttcc tggagcagtc catggtggac aagtccctgg tgagcaggca ggaagctaag    660

atacgggagc tggagacacg cctggagttt gaaaggacgc aagtgaaacg gctggagagc    720

ctggctagcc gtctcaagga aaacatggag aagctgactg aggagcggga tcagcgcatt    780

gcagccgaga accgggagaa ggaacagaac aagcggctac agaggcagct ccgggacacc    840

aaggaggaga tgggcgagct tgccaggaag gaggccgagg cgagccgcaa gaagcacgaa    900

ctggagatgg atctagaaag cctggaggct gctaaccaga gcctgcaggc tgacctaagt    960


<210>  44
<211>  960
<212>  DNA
<213>  Homo sapiens

<400>  44
gagaggtcgc atcaccatca ccatcacgga tcctatttag gtgacactat agaatcgtcg     60

acccacgcgt ccgagaagcg ggagctggag ggcaagctcg ccaccctcag cgaccaggtg    120

aaccggcggg actttgagtc agagaagcgg ctgcggaagg acctgaagcg caccaaggcc    180

ctgctggcag atgcccagct catgctggac cacctgaaga acagtgctcc cagcaagcga    240

gagattgccc agctcaagaa ccagctggag gagtcagagt tcacctgtgc ggcagccgtg    300

aaagcacgga aagcaatgga ggtggagatc gaagacctgc acctgcagat tgatgacatc    360

gccaaagcca agacagcgct ggaggagcag ctgagccgcc ttcagcgtga gaagaatgag    420

atccagaacc ggctggagga agatcaggaa gacatgaacg aattgatgaa gaagcacaag    480

gctgccgtgg ctcaggcttc ccgggacctg gctcagataa atgatctcca agctcagcta    540

gaagaagcca acaaagagaa gcaggagctg caggagaagc tacaagccct ccagagccag    600

gtggagttcc tggagcagtc catggtggac aagtccctgg tgagcaggca ggaagctaag    660

atacgggagc tggagacacg cctggagttt gaaaggacgc aagtgaaacg gctggagagc    720

ctggctagcc gtctcaagga aaacatggag aagctgactg aggagcggga tcagcgcatt    780

gcagccgaga accgggagaa ggaacagaac aagcggctac agaggcagct ccgggacacc    840

aaggaggaga tgggcgagct tgccaggaag gaggccgagg cgagccgcaa gaagcacgaa    900

ctggagatgg atctagaaag cctggaggct gctaaccaga gcctgcaggc tgacctaagt    960


<210>  45
<211>  1226
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (849)..(849)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (885)..(885)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (900)..(900)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (912)..(912)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (953)..(953)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (963)..(963)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1002)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1030)..(1030)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1036)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1049)..(1049)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1051)..(1051)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1083)..(1083)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1100)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1107)..(1107)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1109)..(1109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1114)..(1114)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1120)..(1120)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1128)..(1128)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1130)..(1130)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1134)..(1134)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1146)..(1146)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1154)..(1155)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1158)..(1158)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1160)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1168)..(1168)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1170)..(1170)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1172)..(1172)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1181)..(1181)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1184)..(1184)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1188)..(1188)
<223>  n is a, c, g, or t

<400>  45
aatagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc ggtccgcttt cgtctccgtc ctgctgccgt    120

taccgccgct gctgccgccg cttgcgtccc ccgctccggt ctgtggtgca gccgggaccc    180

aggaccatgt ctctgtctcg ctcagaggag atgcaccggc tcacggaaaa tgtctataag    240

accatcatgg agcagttcaa ccctagcctc cggaacttca tcgccatggg gaagaattac    300

gagaaggcac tggcaggtgt gacgtatgca gccaaaggct actttgacgc cctggtgaag    360

atgggggagc tggccagcga gagccagggc tccaaagaac tcggagacgt tctcttccag    420

atggctgaag tccacaggca gatccagaat cagctggaag aaatgctgaa gtcttttcac    480

aacgagctgc ttacgcagct ggagcagaag gtggagctgg actccaggta tctgagtgct    540

gcgctgaaga aataccagac tgagcaaagg agcaaaggcg acgccctgga caagtgtcag    600

gctgagctga agaagcttcg gaagaagagc cagggcagca agaatcctca gaagtactcg    660

gacaaggagc tgcagtacat cgacgccatc agcaacaagc agggcgagct ggagaattac    720

gtgtccgacg gctacaagac cgcactgaca gaggagcgca ggcgcttctg cttcctggtg    780

gagaagcagt gcgccgtggc caagaactcc gcggcctacc actccaaggg caaggagctg    840

ctggcgcana agctgccgct gtggcaacag gcctgtgccg acccnagcaa gatcccggan    900

cgcgcggtgc anctcatgca gcaggtggcc agcaacggcg ccacccttcc ccnagcgccc    960

tgntcggccc ccaagtccaa cctgggtcat ttccgacccc nnttccgggg ggccaagccc   1020

ctgccggggn cccccnaagc tggcaccgnt ncgtgggggg ggatttctgn cccagaaaaa   1080

ccnacccatc atgaancggn ntccaangnc ccgnatgggn agaaaaanan cccntggggc   1140

tgaccncaag ggtnnccnan ccaaaatncn tntttccccc ngantttnaa aaaaagttta   1200

gggaatctta tttcaaaaaa attccc                                        1226


<210>  46
<211>  1179
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (859)..(859)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (897)..(898)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (906)..(906)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (945)..(945)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (954)..(954)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (979)..(979)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (981)..(981)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (993)..(993)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1018)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1022)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1027)..(1027)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1031)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1036)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1038)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1043)..(1043)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1052)..(1052)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1058)..(1058)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1077)..(1077)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1108)..(1108)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1136)..(1136)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1142)..(1142)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1144)..(1144)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1150)..(1150)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1157)..(1157)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1168)..(1168)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1175)..(1175)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1177)..(1178)
<223>  n is a, c, g, or t

<400>  46
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg ccgccacccg atggaagatt cgatggacat    120

ggacatgagc cccctgaggc cccagaacta tcttttcggt tgtgaactaa aggccgacaa    180

agattatcac tttaaggtgg ataatgatga aaatgagcac cagttatctt taagaacggt    240

cagtttaggg gctggtgcaa aggatgagtt gcacattgtt gaagcagagg caatgaatta    300

cgaaggcagt ccaattaaag taacactggc aactttgaaa atgtctgtac agccaacggt    360

ttcccttggg ggctttgaaa taacaccacc agtggtctta aggttgaagt gtggttcagg    420

gccagtgcat attagtggac agcacttagt agctgtggag gaagatgcag agtcagaaga    480

tgaagaggag gaggatgtga aactcttaag tatatctgga aagcggtctg cccctggagg    540

tggtagcaag gttccacaga aaaaagtaaa acttgctgct gatgaagatg atgacgatga    600

tgatgaagag gatgatgatg aagatgatga tgatgatgat tttgatgatg aggaagctga    660

agaaaaagcg ccagtgaaga aatctatacg agatactcca gccaaaaatg cacaaaagtc    720

aaatcagaat ggaaaagact caaaaccatc atcaacacca agatcaaaag gacaagaatc    780

cttcaagaaa caggaaaaaa ctcctaaaac accaaaagga cctagttctg tagaagacat    840

taaagcaaaa atgcaagcna gtatagaaaa aggtggttct ccttccccaa agtgganncc    900

aattcntcaa ttatgtgaag aattgcttcc ggatgactga ccaanaggct atcnagatct    960

ctggcagtgg aggaagtcnc nttaaaaaaa tantttaaac aattngttaa aaaatttncn   1020

nncttanttc ntttcngnaa canttgaaat cnggctgncc tttttaaaag gcaaaangaa   1080

aactttcccc accggnttga aaaatgtngn ccaggtctat tgccaaaaat ggttgnccaa   1140

angnccgttn atttttnaaa aaggaacncc ccccntnnc                          1179


<210>  47
<211>  856
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (786)..(786)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (804)..(804)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (816)..(816)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (822)..(822)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (829)..(829)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (848)..(848)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (851)..(851)
<223>  n is a, c, g, or t

<400>  47
taagaggaga attaactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgatcccca gcccgccgcc atggccgcct    120

acaaactggt gctgatccgg cacggcgaga gcgcatggaa cctggagaac cgcttcagcg    180

gctggtacga cgccgacctg agcccggcgg gccacgagga ggcgaagcgc ggcgggcagg    240

cgctacgaga tgctggctat gagtttgaca tctgcttcac ctcagtgcag aagagagcga    300

tccggaccct ctggacagtg ctagatgcca ttgatcagat gtggctgcca gtggtgagga    360

cttggcgcct caatgagcgg cactatggcg gtctaaccgg tctcaataaa gcagaaactg    420

ctgcaaagca tggtgaggcc caggtgaaga tctggaggcg ctcctatgat gtcccaccac    480

ctccgatgga gcccgaccat cctttctaca gcaacatcag taaggatcgc aggtatgcag    540

acctcacaga agatcagcta ccctcctgtg agagtctgaa ggatactatt gccagagctc    600

tgcccttctg gaatgaagaa atagttcccc agatcaagga ggggaaacgt gtactgattg    660

cagcccatgg caacagcctc cggggcattg tcaagcatct ggagggtctc tctgaagagg    720

ctatcatgga gctgaacctg ccgactggta ttcccatttg tctatgaatt ggacaagaac    780

ttgaanccta tcaagcccat gcanttttct gggggnatga anagacggng cccaaagcca    840

tggaaagntg nggctg                                                    856


<210>  48
<211>  1371
<212>  DNA
<213>  Homo sapiens

<400>  48
gcccgcctaa gaaacaattg agaggatgca tcaccatcac catcacggtc gacccacgcg     60

tccgcgcgcg gcgaatctca acgctgcgcc gtctgcgggc gcttccgggc caccagtttc    120

tctgctttcc accctggcgc cccccagccc tggctcccca gctgcgctgc cccgggcgtc    180

cacgccctgc gggcttagcg ggttcagtgg gctcaatctg cgcagcgcca cctccatgtt    240

gaccaagcct ctacaggggc ctcccgcgcc ccccgggacc cccacgccgc cgccaggagg    300

caaggatcgg gaagcgttcg aggccgagta tcgactcggc cccctcctgg gtaagggggg    360

ctttggcacc gtcttcgcag gacaccgcct cacagatcga ctccaggtgg ccatcaaagt    420

gattccccgg aatcgtgtgc tgggctggtc ccccttgtca gactcagtca catgcccact    480

cgaagtcgca ctgctatgga aagtgggtgc aggtggtggg caccctggcg tgatccgcct    540

gcttgactgg tttgagacac aggagggctt catgctggtc ctcgagcggc ctttgcccgc    600

ccaggatctc tttgactata tcacagagaa gggcccactg ggtgaaggcc caagccgctg    660

cttctttggc caagtagtgg cagccatcca gcactgccat tcccgtggag ttgtccatcg    720

tgacatcaag gatgagaaca tcctgataga cctacgccgt ggctgtgcca aactcattga    780

ttttggttct ggtgccctgc ttcatgatga accctacact gactttgatg ggacaagggt    840

gtacagcccc ccaaagtgga tctctcgaca ccagtaccat gcactcccgg ccactgtctg    900

gtcactgggc atcctcctct atgacatgga gtgtggggaa attccctttt gaaagggaac    960

aagaaaatcc tggaaactga aactccactt cccaacccag gtctccccaa aatgctgtgc   1020

cctaatccac cggtgcctgg cccccaaccc ttctccccaa cctacctgga aaaaacccgc   1080

tgaaccccta aaagacaacc cactcagaaa ttacccctca tcccctcaag aggcacttcc   1140

cccttcgccc tctccatcac acttaaccat aaagaacgct cgactgccat ccactacaca   1200

acactcctac cagccaaacc cctcatacat gcaatatacc actctcaatc actactccat   1260

caaacttcac aacaccactc aacaaacccc ctcccattac acgatacaca atatacatat   1320

cacaaccaac ctcacacgct acataacatt cctaccaacc cacattcaca t            1371


<210>  49
<211>  1178
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (781)..(781)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (870)..(870)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (888)..(888)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (894)..(894)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (924)..(924)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (978)..(978)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (996)..(996)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1007)..(1007)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1014)..(1014)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1028)..(1028)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1034)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1041)..(1041)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1045)..(1045)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1053)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1060)..(1060)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1063)..(1063)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1072)..(1072)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1076)..(1076)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1083)..(1083)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1121)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1126)..(1127)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1131)..(1131)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1146)..(1146)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1154)..(1154)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1157)..(1157)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1161)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1168)..(1168)
<223>  n is a, c, g, or t

<400>  49
naattagaga aattactatg aagaggatcg catcaccatc accatcacgg atcctattta     60

ggtgacacta tagaatcgtc gacccacgcg tccgggctgg agcgcatctg gtcctccgcg    120

cggaaagcgc tgcttttgcc tggccgccct agccgctggc tcatccaagt ggccttcgcc    180

gctctcttgc gtcccaacca gagcgctggc cacctcgccg cccagctcac gccgcgcccg    240

cgctcccagg ctccgggttt tcttaaatgt tttcttggag ccttaaagat ggagatgaca    300

gaaatgactg gtgtgtcgct gaaacgtggg gcactggttg tcgaagataa tgacagtgga    360

gtcccagttg aagagacaaa aaaacagaag ctgtcggaat gcagtctaac caaaggtcaa    420

gatgggctac agaatgactt tctgtccatc agtgaagacg tgcctcggcc tcctgacact    480

gtcagtactg ggaaaggtgg aaagaattct gaggctcagt tggaagatga ggaagaagag    540

gaggaagatg gactttcaga ggagtgcgag gaggaggaat cagagagttt tgcagacatg    600

atgaagcatg gactcactga ggctgacgta ggcatcacca agtttgtgag ttctcatcaa    660

gggttctcgg gaatcttaaa agaaagatac tccgacttcg ttgttcatga aataggaaaa    720

gatggacgga tcagccattt gaatgacttg tccattccag tggatgagga ggacccttca    780

naagacatat ttacagtttt gacagctgaa gaaaagcagc gattggaaga gctccagctg    840

ttcaaaaata aggaaaccag tgttgccatn gaggttatcg aggacccnaa aaanaaaaga    900

accatcatcc atcaggctat caantctctg tttccggatt aaagacaaaa accgaggata    960

ggggagggga gaaatacntt gtancctacc ccccanctgg gaaaaangct ttgncaatan   1020

gggtctgnga acanntcctc ntgcnagcaa ccntgagggn agncccctcn tnttancttg   1080

ccnttcggtt caaggctact naaggntgcn caaaaaaatt natctnnccc ncctcaaaag   1140

ggaaantgtc cttnaangcn ngcaattntg acctgctg                           1178


<210>  50
<211>  1191
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (784)..(784)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (847)..(847)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (919)..(919)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (934)..(934)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (955)..(955)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (978)..(978)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1016)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1028)..(1028)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1033)..(1033)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1043)..(1043)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1046)..(1046)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1052)..(1052)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1097)..(1097)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1108)..(1108)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1112)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1136)..(1136)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1144)..(1144)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1156)..(1156)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1170)..(1170)
<223>  n is a, c, g, or t

<400>  50
nantagagaa attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cgccaaaatg tcaaaaagac catcttatgc    120

cccacctccc accccagctc ctgcaacaca aatgcccagc acaccagggt ttgtgggata    180

caatccatac agtcatctcg cctacaacaa ctacaggctg ggagggaacc cgggcaccaa    240

cagccgggtc acggcatcct ctggtatcac gattccaaaa cccccaaagc caccagataa    300

gccgctgatg ccctacatga ggtacagcag aaaggtctgg gaccaagtaa aggcttccaa    360

ccctgaccta aagttgtggg agattggcaa gattattggt ggcatgtggc gaggagaaga    420

aagacgacga gaacattccg atggagacag aggagacaca ccttgaagaa acaacagaga    480

gccaacagaa tgatgaagaa aaacaagaat atttaaacga atacgaagca gaaaagatag    540

agtacaatga atctatgaag gcctatcata attcccccgc gtaccttgct tacataaatg    600

caaaaagtcg tgcagaagct gctttagagg aagaaagtcg acagagacaa tctcgcatgg    660

agaaaggaga accgtacatg agcattcagc ctgctgaaga tccagatgat tatgatgatg    720

gcttttcaat gaagcataca gccaccgccc gtttccagag aaaccaccgc ctcatcagtg    780

aaanttctta gtgagagtgt ggtgccagac gttcggtcag ttgtcacaac agctagaatg    840

caggtcntca aacggcaggt ccagtcctta atggttcatc agcgaaaaac tagaagctga    900

acttcttcaa atagagganc gacccccgga aaanaagaga aattcctgga aagcncagat    960

tctttnacaa tgaacttnaa aggttgggcg gtctgaaagt aaaagtggat ttgganaaaa   1020

ttgcaccnaa atngcccagn canagnaacg gncccccaaa ggcaggagga aagggaaaaa   1080

gaggccccaa acaagtngac ncattnanac anctctttct gaggaaaaaa accccntaca   1140

aggngaggaa aaaaanacac caaactttcn atggaacaag gggtccacat t            1191


<210>  51
<211>  1179
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (14)..(14)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (916)..(916)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (921)..(921)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (952)..(952)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (957)..(957)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (967)..(967)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1013)..(1013)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1024)..(1024)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1037)..(1037)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1043)..(1043)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1061)..(1061)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1078)..(1078)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1091)..(1091)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1097)..(1097)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1120)..(1120)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1125)..(1125)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1127)..(1127)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1131)..(1131)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1136)..(1136)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1142)..(1142)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1157)..(1157)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1160)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1168)..(1168)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1174)..(1174)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1177)..(1177)
<223>  n is a, c, g, or t

<400>  51
atagagaaat tacnatgaga ggatcgcatc accatcacca ttcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gctctcggca caagcatgta cggcaaaggc    120

aagagtaaca gcagcgccgt cccgtccgac agccaggccc gggagaagtt agcactctac    180

gtatatgaat atctgctcca tgtaggagct cagaaatcag ctcaaacatt tttatcagag    240

ataagatggg aaaaaaacat cacattgggg gaaccaccag gattcttaca ttcttggtgg    300

tgtgtatttt gggatctcta ctgtgcagct ccagagagac gtgaaacatg tgaacactca    360

agtgaagcaa aagccttcca tgattacagt gctgcagcag ctcccagtcc agtgctagga    420

aacattcccc caggagatgg catgccagta ggtcctgtac caccagggtt ctttcaggca    480

cttggaggtg tcccaggaag tcagccatta ctccccagtg gaatggatcc aactcgacaa    540

caaggacatc caaatatggg tgggccaatg cagagaatga ctcctccaag aggaatggtg    600

cccttaggac cacagaacta tggaggtgca atgagacccc cactgaatgc tttaggtggc    660

cctggaatgc ctggaatgaa catgggtcca ggtggtggta gaccttggcc aaacccaaca    720

aatgccaatt caataccata ctcctcagca tctcctggga attatgtagg tcctccagga    780

ggtggagggc caccaggaac acccatcatg cctagtccag cagattcaac caactctggt    840

gataacatgt atactttaat gaatgcagta cctcctggac ctaacagacc taattttcca    900

atgggccctg ggtcanatgg ntcccatggg tggattagga ggaatggagt cncatcncat    960

gaatggnctc tttaggctca gaanatatgg acagtanttc caaaaattct ccnataaaat   1020

gaancctgaa taatcanccg ggncctccaa gggatgatgg ncaaaatggg ggggaaantt   1080

tcttaaattc nttttcnaag ngaaanttac tcccctaacn tgganangag nggggngatc   1140

cnttaccaag tcccccnagn aaaacccnag ggantcncc                          1179


<210>  52
<211>  1337
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (919)..(919)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (924)..(924)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (941)..(941)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (958)..(958)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (960)..(960)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (968)..(968)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (985)..(985)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1011)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1021)..(1021)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1026)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1034)..(1034)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1041)..(1041)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1047)..(1047)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1052)..(1052)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1063)..(1063)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1065)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1075)..(1075)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1080)..(1080)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1097)..(1097)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1112)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1144)..(1144)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1148)..(1148)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1151)..(1151)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1158)..(1158)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1161)..(1161)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1172)..(1172)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1178)..(1178)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1186)..(1187)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1189)..(1189)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1219)..(1219)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1231)..(1231)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1238)..(1239)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1242)..(1242)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1245)..(1245)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1256)..(1256)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1260)..(1260)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1262)..(1262)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1268)..(1268)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1276)..(1276)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1280)..(1280)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1287)..(1287)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1300)..(1300)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1303)..(1303)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1310)..(1310)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1317)..(1317)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1323)..(1324)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1333)..(1334)
<223>  n is a, c, g, or t

<400>  52
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg gatgacgaaa ggcatcacca tggcaacagc    120

caaagccgtg gcagctggga actcatgtag acaggaggac gtgattgcta ctgccaacct    180

gagccggaaa gccgtgtcag atatgttgac ggcttgcaag caagcatcct tccaccccga    240

tgtcagtgac gaggtgagaa ccagagcctt gcgtttcggg acggagtgca cccttggcta    300

cttggacctc ctggagcacg tcttggtgat tcttcagaaa ccaaccccag aattcaagca    360

gcagctggcc gctttctcca agcgagtcgc cggcgctgtg acagagctca tccaggcggc    420

ggaagccatg aaaggaacag agtgggtgga tccagaagac ccaactgtca ttgcagaaac    480

agagttactg ggggctgcag catccatcga agctgctgct aagaagttag agcaactgaa    540

gccaagagca aaaccaaaac aagcggatga gaccctggac tttgaggaac agatcttgga    600

agctgctaaa tccattgctg ctgccacaag cgccctggtc aaatcggcct cagcagccca    660

gagggagctg gtggcccaag gaaaggtggg ctccatccct gccaatgctg cagacgacgg    720

acagtggtca caggggctga tttctgctgc ccggatggtg gcggctgcga ccagcagtct    780

ctgtgaggcg gccaatgcct ccgttcaggg acacgccagc gaggagaagc tcatctcatc    840

tgccaagcaa ggtcgccgct tccacggctc aactgctggt ggcctgcaag gtgaaaggcc    900

gaccaggatt cagaggccna tgangcggct acaggcggca ngaaatgctg tgaaaaanan    960

cctcaaanaa tcttgtccgt gccancccaa aaaggcagct ttttggcaaa nctgaatgac   1020

naccantttt nnantggaaa ncccaanttt tngggggggg cantngcttn aaatnattcn   1080

ccccccaaaa aaaaatngtt aaaaaaaaac cnaaaaattg gaaaaaacca aggaaaaaac   1140

tggncccnaa ntcccccnac nacaatataa antttttncc ccccanntna aggaaaataa   1200

aggctaaagg tccaacccna atgggacccc nggggatnnc cntgnttaaa tggaanaaan   1260

tnttcttnaa aagtgnggcn cttactngaa accccccccn ccncccgggn aaaccgnaac   1320

ccnngggttt ttnncca                                                  1337


<210>  53
<211>  1268
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (705)..(705)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1243)..(1243)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1261)..(1261)
<223>  n is a, c, g, or t

<400>  53
ngggatatac tgacttacct ataaaaaggc gtatcacgag gccctttcgt cttcacctcg     60

agaaatcata aaaaatttat ttgctttgtg agcggataac aattataata gattcaattg    120

tgagcggata acaatttcac acagaattca ttaaagagga gaaattaact atgagaggat    180

cgcatcacca tcaccatcac ggtcgaccca cgcgtccgcc cacgcgtccg cggggtggca    240

tggcagcgag cacagacatg gctgggctgg aggagagctt ccgcaagttt gccatccatg    300

gtgaccccaa ggccagtggg caagagatga atggcaagaa ctgggccaag ctgtgcaagg    360

actgcaaggt ggctgacgga aagtccgtga cagggaccga tgtggacatc gtcttctcca    420

aagtcaaggg gaagtctgct cgggtcatca actatgagga gttcaagaag gccctggaag    480

agctggcgac caagagattc aaggggaaga gcaaggagga ggccttcgat gccatctgcc    540

agctggtggc aggcaaagag ccagccaatg tgggcgtcac taaagcaaaa acagggggtg    600

ctgtagaccg gctgacggac accagcagat acacgggctc ccacaaggag cgcttcgatg    660

agagcggcaa gggcaagggc attgcgggac ggcaggacat cctgnacgac agtggctacg    720

tgagcgccta caagaatgca ggcacctacg atgccaaggg tgagaagtga ggcttgggaa    780

gaccgccctg ccaagtgcgg ctgcccctgc cagaggctca ggcctgggtc taaggggcac    840

gggaagcaag aaatcctggt cccctccccg gtggacctgc ccccaaaacc tcctgcctaa    900

cccactgggc tggcccacag gccccttgac caggttgctc gggggccctt cccccctccc    960

ttcccggtcc aattttgggc ccccggggga aaactgggcc agaagccccc aaacccccgg   1020

acgccaaatc caggcgaaca ccaataagcg gaccggaacc ccgaacgaaa aaccgcaaaa   1080

ggcccaaaac actgaccgga gggagtcaaa gaacagggag ccgcagggcg acacagcgat   1140

gacaacagcc aacatgcgac cggattccgc acacggagcc agggatagaa acaaaaaacc   1200

gcgataccgc cgacgaagat acgaaaggac accccccagc agnaagagac agaaggacgg   1260

nacaaaac                                                            1268


<210>  54
<211>  1241
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (930)..(930)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1007)..(1007)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1038)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1043)..(1043)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1050)..(1050)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1067)..(1067)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1095)..(1095)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1097)..(1097)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1107)..(1107)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1126)..(1126)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1150)..(1150)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1160)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1166)..(1166)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1168)..(1168)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1171)..(1171)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1173)..(1174)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1178)..(1179)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1185)..(1185)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1188)..(1191)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1193)..(1194)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1200)..(1200)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1210)..(1210)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1215)..(1215)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1219)..(1219)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1223)..(1223)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1234)..(1234)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1236)..(1236)
<223>  n is a, c, g, or t

<400>  54
tagaggaaat tactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg cccacgcgtc cgcggacgcg tgggttcatg    120

actgcagtgc ctcatttgag gaggagccag gagcggacaa ggttgagaac aaatctaatg    180

aagatgtgaa ttcctctgaa ctagatgaag aatacctaat agaactggaa aaaaacatgt    240

cggatgaaga gaaacagaaa agaagagaag agagcactag actaaaggag gagggaaatg    300

aacagtttaa gaaaggagat tatatagaag ctgaaagttc ttatagtcga gccctcgaaa    360

tgtgcccatc ctgcttccaa aaggagaggt cgattctatt ttcaaataga gctgcagcaa    420

ggatgaaaca ggacaagaaa gaaatggcca tcaatgactg cagcaaagca attcaattaa    480

accccagcta tatcagggca atattgagga gagcagagtt gtatgagaag acggacaagc    540

tagatgaagc cctggaagac tataaatcta tattagaaaa agatccatca atacatcaag    600

caagagaagc ttgtatgaga ttacctaagc aaattgaaga acgtaatgaa agactaaaag    660

aagagatgtt aggtaaatta aaagatcttg ggaacttggt tctccgacct tttgggctct    720

ccacggaaaa tttccagatc aaacaggatt cctctaccgg ctcgtactcc atcaatttcg    780

ttcaaaatcc aaataataac agataacaaa gataacaaaa gctttacaag ctgacttgga    840

attgtgtgct gcttgctgtt agctagggga aaggccctgc caatgtttaa cttttaaagc    900

atcttatcta aaagaaaggc tatccagtan agcccagtgc tcccttgtcc ctcttttatg    960

atcagggtga aatgtacttc ctgatgtatg aacctaattt gattccnttt taaggggggt   1020

ctgtgcactg ggtccccnan tcngctgtcn ttgtccggaa aaacccnttt tttgaggctg   1080

acttcctgat ctacncnccc cgcccancaa agcccctctg accaanaacc tgttggtggg   1140

aacctgcccn aaatgatgan gacggntncc ncnngtgnnc ccccntannn nanntaaaan   1200

gtgccccccn tttcngatnc ccngggaaaa aacntntggt t                       1241


<210>  55
<211>  483
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (234)..(234)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (290)..(290)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (294)..(294)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (298)..(298)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (315)..(315)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (409)..(409)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (411)..(411)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (415)..(415)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (438)..(438)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (443)..(444)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (448)..(450)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (456)..(456)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (465)..(465)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (467)..(467)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (472)..(472)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (476)..(476)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (480)..(480)
<223>  n is a, c, g, or t

<400>  55
tgaatagaga gaattactat gagaggatcg catcaccatc accatcacgg gatcctattt     60

aggtgacact atagaatcgt cgacccacgc gtccgcggac gcgtggggga gcatcccctg    120

tccctgtgtg agcaggtggc ccccatcatt gacctcatgg ccgtcagcaa tgcgcttttt    180

gccaagctcc gggacttcat caccctgcgt ctgcctcctg gcttcccagt taanattgaa    240

atcccgatct tccacatcct caacgcccgc atcaccttcg ggaacctcan cggntgcnac    300

gaaccggtgc catcngtgcg aggcagcccc agcagcgaga cgccttcccc aggcagcgac    360

tcctccagcg tcagcagctc cagctccacg acctcctgcc gcggctgcna natcncccca    420

gcgttgttcg aggccccncg cgnntacnnn catgangggc tggcnancgg gnggcngtan    480

acc                                                                  483


<210>  56
<211>  966
<212>  DNA
<213>  Homo sapiens

<400>  56
catcaccatc accatcacgg atcctattta ggtgacacta tagaatcgtc gacccacgcg     60

tccgggctga cccagctcca gctgctgacc caggtcctgt tcgagaacca gctgctgcag    120

atcggagtca agtcagagtt ccgacagaac ctgggccgca tgtatctctt ctatggcaac    180

aagacctcgg tgcagttcca gaatttctca cccactgtgg ttcacccggg agacctccag    240

actcagctgg ctgtgcagac caagcgcgtg gcggcgcagg tggacggcgg cgcgcaggtg    300

cagcaggtgc tcaatatcga gtgcctgcgg gacttcctga cgcccccgct gctgtccgtg    360

cgcttccggt acggtggcgc cccccaggcc ctcaccctga agctcccagt gaccatcaac    420

aagttcttcc agcccaccga gatggcggcc caggatttct tccagcgctg gaagcagctg    480

agcctccctc aacaggaggc gcagaaaatc ttcaaagcca accaccccat ggacgcagaa    540

gttactaagg ccaagcttct ggggtttggc tctgctctcc tggacaatgt ggaccccaac    600

cctgagaact tcgtgggggc ggggatcatc cagactaaag ccctgcaggt gggctgtctg    660

cttcggctgg agcccaatgc ccaggcccag atgtaccggc tgaccctgcg caccagcaag    720

gagcccgtct cccgtcacct gtgtgagctg ctggcacagc agttctgagc cctggactct    780

gccccggggg atgtggccgg cactgggcag ccccttggac tgaggcagtt ttggtggatg    840

ggggacctcc actggtgaca gagaagacac cagggtttgg gggatgcctg ggactttcct    900

ccggcctttt gtatttttat ttttgttcat ctgctgctgt ttacattctg gggggttagg    960

gggagt                                                               966


<210>  57
<211>  881
<212>  DNA
<213>  Homo sapiens

<400>  57
tgagaggatc gcatcaccat caccatcacg gatcctattt aggtgacact atagaatcgt     60

cgacccacgc gtccgaaaaa gcatccaatc ccgtggaggt tggcatccag gtcacgccag    120

aggatgacga ttgtttatca acgtcatcta gaggaatttg ccccaaacag gaacacatag    180

cagataaact tctgcactgg aggggcctct cctcccctcg ttctgcacat ggagctctaa    240

tccccacgcc tgggatgagt gcagaatatg ccccgcaggg tatttgtaaa gatgagccca    300

gcagctacac atgtacaact tgcaaacagc cattcaccag tgcatggttt ctcttgcaac    360

acgcacagaa cactcatgga ttaagaatct acttagaaag cgaacacgga agtcccctga    420

ccccgcgggt tcttcacaca cccccattcg gcgtagtacc cagagagctc aagatgtgtg    480

gcagttttcg gatggaagct cgagagccct taagttctga gaaaatttga agcccccagg    540

ggtggggtgg acgcgtgccg cccagtcgac gtcagcgtgg tctgtcatcc tgctagtttg    600

tgatgttttc tgacagtagc ctccaagaag ccgttgtgcg aagacagagt cctgcagagt    660

ccttccagcc taggcctgca gcgccatttt atttatattt tttaataaaa agtaaaaaca    720

aaaaaacaga cccacattgg aacagtgaat cagtcccata gagagggccc gtggaccatc    780

gctgtcatga gtgatgccct ggcccttctg aaaccagcca acctaattac ctgtattgtg    840

gaaatgcgca tgagtcccca accccttgtt tctatacatt c                        881


<210>  58
<211>  1215
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (864)..(864)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (908)..(908)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (917)..(917)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (948)..(948)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (959)..(959)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (990)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (998)..(998)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1036)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1048)..(1048)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1060)..(1060)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1063)..(1063)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1066)..(1066)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1085)..(1085)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1091)..(1091)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1093)..(1093)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1099)..(1099)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1103)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1119)..(1119)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1125)..(1125)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1132)..(1132)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1140)..(1140)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1145)..(1145)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1151)..(1152)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1155)..(1155)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1163)..(1164)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1167)..(1167)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1181)..(1181)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1184)..(1184)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1187)..(1187)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1190)..(1190)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1194)..(1195)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1201)..(1201)
<223>  n is a, c, g, or t

<400>  58
gagaaattac tatgagagga tcgcatcacc atcaccatca cggatcctat ttaggtgaca     60

ctatagaatc gtcgacccac gcgtccgcgg ctgcggcgct ttgtgctcca gtcgctccta    120

acgctccctg gcccggccgg ggccgcgcag ttagggcatc tgaggcgggg agaagcggcg    180

gggagacgcc ggctgccagc atgtcgctgc ctccggagaa agcctccgag ctgaagcagc    240

tcatccacca gcagctgagc aagatggatg tccatggtag aataagagaa atccttgctg    300

agactatacg ggaagaattg gcacctgatc aacagcattt atcaacagaa gatttgatca    360

aagcccttag acgtcgagga atcattgacg atgtgatgaa agaacttaat tttgttactg    420

acagtgttga gcaagaactc ccttcctctc caaaacaacc tatttgtttt gatagacaat    480

cgacattaaa aaaaactaat attgatccaa cacggaggta tctttacctt caggttttgg    540

gtggaaaagc tttcttggaa catctgcaag aacctgagcc tttacctgga caagtttgtt    600

caacgtttac tttatgttta cattatcgaa accaacgttt tcgttctaaa cctgttccat    660

gtgcctgtga accagatttt catgatggct ttttacttga agtacacaga gaaagcttgg    720

gtgatggaac tagaatggct gattcaacaa caatgttatc aataagtgat ccaattcata    780

tggtgctaat caaaacagac atatttggtg agacgacttt agtagcatca tattttctgg    840

aatggcgatc ggttttgggc tcanaaaatg gagtgaccag tctgactgtg gaacttatgg    900

gtgcacanaa tcaaaangtt tctgtgggaa tttaaatata aaacttgnaa atgtatccnc    960

cactcaatca aacgttatct caagaantan tgaacacnca gctgnctttg gaacgtcaaa   1020

aactgcaaaa aaaaancgat tatttctngt atatgctaan canggnggan aaatattgca   1080

attcnacctc nanaactcng annggttaaa attttgccng gttgnaaatt anttaaaaan   1140

tttangccgg nnttnaaatt tannggnagg ggggaaattc nttnaanttn tttnnaaagg   1200

nttcccaaaa aaaaa                                                    1215


<210>  59
<211>  1150
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (846)..(846)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (884)..(884)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (928)..(928)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (930)..(930)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (953)..(953)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (958)..(958)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (963)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (975)..(975)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (981)..(981)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1000)..(1000)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1018)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1057)..(1057)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1061)..(1061)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1066)..(1066)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1072)..(1072)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1078)..(1078)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1084)..(1084)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1103)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1108)..(1108)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1113)..(1113)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1117)..(1117)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1121)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1124)..(1124)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1136)..(1137)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1147)..(1147)
<223>  n is a, c, g, or t

<400>  59
naatagagaa attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cgtggtgcgc tgtcttcccg cttgcgtcag    120

ggacctgccc gactcagtgg ccgccatggc atcagatgaa ggcaaacttt ttgttggagg    180

gctgagtttt gacaccaatg agcagtcgct ggagcaggtc ttctcaaagt acggacagat    240

ctctgaagtg gtggttgtga aagacaggga gacccagaga tctcggggat ttgggtttgt    300

cacctttgag aacattgacg acgctaagga tgccatgatg gccatgaatg ggaagtctgt    360

agatggacgg cagatccgag tagaccaggc aggcaagtcg tcagacaacc gatcccgtgg    420

gtaccgtggt ggctctgccg ggggccgggg cttcttccgt gggggccgag gacggggccg    480

tgggttctct agaggaggag gggaccgagg ctatgggggg aaccggttcg agtccaggag    540

tgggggctac ggaggctcca gagactacta tagcagccgg agtcagagtg gtggctacag    600

tgaccggagc tcgggcgggt cctacagaga cagttacgac agttacgcta cacacaacga    660

gtaaaaaccc ttcctgctca agatcgtcct tccaatggct gtgtgtttaa agattgtggg    720

agcttcgctg aacgttaatg tgtagtaaat gcacctcctt gtattcccac tttcgtagtc    780

atttcggttc tgatcttgtc aaacccagcc tgaccgcttc tgacgccggg atggcctcgt    840

tactanactt ttctttttta aggaagtgct gttttttttt tganggtttt caaaacattt    900

tgaaaagcat ttactttttt tgaccacnan ccatgaattt ttcaaaaaaa tcnggggntg    960

ggnngggttt ttggnttttg ntttaanttt tgggttgccn ttgccntttt tttttttnag   1020

gggggttggc ccccntgaaa gggggtgccc cccctcnctt nctctnaaan tnaaacgnaa   1080

ttgnaaatcc cccccttttt cnnaaacntn aancaanctg nggntttttt tccaannccc   1140

ggggaanctt                                                          1150


<210>  60
<211>  856
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (581)..(581)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (706)..(706)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (734)..(734)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (746)..(746)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (802)..(802)
<223>  n is a, c, g, or t

<400>  60
attacttgag aggtcgcatc accatcccat cacggatcct atttaggtga cactatagaa     60

tcgtcgactc tggaccttgg ctgtcactca gttaaagaag cagtagtggg tgccatgcac    120

attcaggtga atccgccata ctacatcccg ctggttgagc tggtccccca cccggagacg    180

gcccctacga cagtggacag aacccacgcc ctgatgaaga agattggaca gtgccccatg    240

cgagtccaga aggaggtggc cggcttcgtt ctgaaccgcc tgcaatatgc aatcatcagc    300

gaggcctggc ggctagtgga ggaaggaatc gtgtctccta gtgacctgga ccttgtcatg    360

tcagaagggt tgggcatgcg gtatgcattc attggacccc tggaaaccat gcatctcaat    420

gcagaaggta tgttaagcta ctgcgacaga tacagcgaag gcataaaaca tgtcctacag    480

acttttggac ccattccaga gttttccagg gccactgctg agaaggttaa ccaggacatg    540

tgcatgaagg tccctgatga cccggagcac ttagctgcca ngaggcagtg gagggacgag    600

tgcctcatga gactcgccaa gttgaagagt caagtgcagc cccagtgaat ttcttgtaat    660

gcagcttcca ctcctctcat tggaggccct atttggggac actgcnagcc ccttaatcac    720

cctctgtgac atangtagca gccccngaga atctaagctg gctgtcttgt gtgcaccctg    780

aatggggtgt gcaagcccgt antctcccgt cacttggatc aaaccctggg ctggcggccc    840

acaccactgc gttccg                                                    856


<210>  61
<211>  1268
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (128)..(128)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (911)..(911)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (954)..(954)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (978)..(978)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (983)..(983)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (989)..(989)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1051)..(1051)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1063)..(1063)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1114)..(1114)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1126)..(1126)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1135)..(1135)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1145)..(1145)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1149)..(1149)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1169)..(1169)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1177)..(1177)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1179)..(1179)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1184)..(1184)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1191)..(1191)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1206)..(1206)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1210)..(1210)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1214)..(1214)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1216)..(1216)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1221)..(1221)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1234)..(1234)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1237)..(1237)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1250)..(1250)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1266)..(1266)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1268)..(1268)
<223>  n is a, c, g, or t

<400>  61
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc acagagctca gtgcaaccac cagaaggaga    120

cagtgaanca aaagctcctg aagaatcatc agaggatgtg acaaaatatc aggaaggagt    180

atctgcagaa aacccagttg agaaccatat caatataaca caatcagata agttcacagc    240

caagccattg gattccaact caggagaaag aaatgacctc aatcttgatc gctcttgtgg    300

ggttccagaa gaatctgctt catctgaaaa agccaaggaa ccagaaactt cagatcagac    360

tagcactgag agtgctacca atgaaaataa caccaatcct gagcctcagt tccaaacaga    420

agccactggg ccttcagctc atgaagaaac atccaccagg gactctgctc ttcaggacac    480

agatgacagt gatgatgacc cagtcctgat cccaggtgca aggtatcgag caggacctgg    540

tgatagacgc tctgctgttg cccgtattca ggagttcttc agacggagaa aagaaaggaa    600

agaaatggaa gaattggata ctttgaacat tagaaggccg ctagtaaaaa tggtttataa    660

aggccatcgc aactccagga caatgataaa agaagccaat ttctggggtg ctaactttgt    720

aatgagtggt tctgactgtg gccacatttt catctgggat cggcacactg ctgagcattt    780

gatgcttctg gaagctgata atcatgtggt aaactgcctg cagccacatc cgtttgaccc    840

aattttagcc tcatctggca tagattatga cataaagatc tggtcaccat tagaagagtc    900

aaggattttt naaccgaaaa cttgctgatg aagttataac tcgaaacgaa ctcntgctgg    960

aagaaactag aaacaccntt acngttccng cctctttcat gttgaggatg ttggcttccc   1020

ttaatcatat ccganctgac ggttggaggg ngacaaatca aangctctgg ncacaaaatg   1080

gaaatgagga tgaggataat aactcntttg gcanccctta atgtcngaat ttgtnaaaaa   1140

ctttnttant ttttttctta caaactttng gcatttnang gtanggtttg naattttccc   1200

tttttnggan accnanattg nttggaaaat gggngcnaaa tttgggaatn ttaaaacaaa   1260

ctcccnan                                                            1268


<210>  62
<211>  803
<212>  DNA
<213>  Homo sapiens

<400>  62
tgagaaatta ctatgagagg atcgcatcac catcaccatc acggatccta tttaggtgac     60

actatagaat cgtcgaccca cgcgtccggg aggcgacgcg ccggaggaaa gatggaagac    120

taccaggctg cggaggagac tgcttttgtt gttgatgaag tgagcaacat tgtaaaagag    180

gctatagaaa gcgcaattgg tggtaacgct tatcaacaca gcaaagtgaa ccagtggacc    240

acaaatgtag tagaacaaac tttaagccaa ctcaccaagc tgggaaaacc atttaaatac    300

atcgtgacct gtgtaattat gcagaagaat ggagctggat tacacacagc aagttcctgc    360

ttctgggaca gctctactga cgggagctgc actgtgcgat gggagaataa gaccatgtac    420

tgcatcgtca gtgccttcgg actgtctatt tgacctgcag tccagcctat ggcctttctc    480

cttttgtctc tagttcatcc tctaaccacc agccatgaat tcagtgaact cttttctcat    540

tctctttgtt ttgtggcact ttcacaatgt agaggaaaaa accaaatgac cgcactgtga    600

tgtgaatggc accgaagtca gatgagtatc cctgtaggtc acctgcagcc tgcgttgcca    660

cttgtcttaa ctctgaatat ttcatttcaa aggtgctaaa atctgaaatc tgctagtgtg    720

aaacttgctc tactctctga aatgattcaa atacactaat tttccatact ttatactttt    780

gttagaataa attattcaaa tct                                            803


<210>  63
<211>  972
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (604)..(604)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (650)..(650)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (653)..(653)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (672)..(672)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (691)..(691)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (694)..(694)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (698)..(698)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (701)..(701)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (705)..(705)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (723)..(723)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (733)..(733)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (739)..(740)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (746)..(746)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (750)..(751)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (759)..(759)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (794)..(794)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (799)..(799)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (817)..(817)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (824)..(824)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (829)..(830)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (833)..(833)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (838)..(838)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (849)..(849)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (886)..(887)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (891)..(891)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (913)..(913)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (922)..(922)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (930)..(930)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (936)..(936)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (946)..(946)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (961)..(961)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (969)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (971)..(971)
<223>  n is a, c, g, or t

<400>  63
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc gggcggcggc ggagcgggcg gcggagcggc    120

ggcagcagcg gtgagcgcga gccccggagc cccgggcggc cggcctcccg cgcccgcgca    180

gccccgcgtc tgcgtccggc cggagacgcc gggccccgcg ccgcgccgcg ccatgtcggt    240

gaacatggac gagctgcggc accaggtcat gatcaaccag ttcgtgctgg ccgcgggctg    300

cgcggccgac caggcgaagc agttgctgca ggcggcccac tggcagttcg agaccgcgct    360

gagcacgttc ttccaagaaa ccaacattcc caacagccac caccaccacc agatgatgtg    420

cactcccagc aacacccctg ccacgccgcc caacttcccc gatgcgctgg ccatgttctc    480

caagctccgc gcctccgagg gcctgcagag cagcaacagc cccatgacag ccgcagcctg    540

ctccccacct gcaaacttca gccccttctg ggcctcgtcc ccgcccagcc accaggcgcc    600

ctgnatcccg ccctcctccc ccaccacctt ccaccacctc caccgcccan agnccaagtg    660

gcccccagga tnacagcatg ggggcgccca ncanaaancc ntggnggcca tggacggcca    720

aanattaaac tgnacgccnn ctggcnctgn ntggaaatng ggtgcacccc taggtttgtg    780

gggaacacag taanggtcna tgggaggggg gaacccnggg aagngctann ggnttttncc    840

aaaaatccnc tggaaaaaat tttttaaaaa aaatttttgt ggggtnnggg naaaaaaaaa    900

aattttcctt ganccaattg gnttcttttn aaaaantttt ttaggnaaat ttttttcctt    960

ntttttttna na                                                        972


<210>  64
<211>  1426
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (13)..(14)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (735)..(735)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (757)..(757)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (777)..(777)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (829)..(829)
<223>  n is a, c, g, or t

<400>  64
nnggctaatc tcnncctaag aatactatag aggatcgcat caccatcacc atcacggtcg     60

acccacgcgt ccgcgtaaag ctaatccaca ggataaagta catcccaata aagcggaatt    120

catcagagcc aagtatcaga tgttagcgtt cgtccatcgc ttgccctgcc gggatgacga    180

tagtgtgact gccaaagatc ttagcaagca actccattcg agcgtgagaa cagggaatct    240

tgaaacctgt ttgagactgt tatctttagg agcacaagcc aacttctttc atcctgaaaa    300

aggaaacacc ccactccatg ttgcctccaa agcagggcag attttacagg ctgaattatt    360

ggcagtatat ggagcagacc caggcacaca ggattctagt gggaaaactc ccgttgatta    420

tgcaaggcaa ggagggcacc atgagctggc agagcgcctc gtggaaatac agtatgagct    480

aacggacaga ctagccttct atctctgtgg caggaaacca gatcacaaaa atggacagca    540

ctttataata cctcaaatgg cagacagcag cctggatttg tctgaattgg caaaagctgc    600

taagaagaaa cttcaatctc taagtaatca tttgtttgaa gaacttgcca tggatgtgta    660

cgatgaagtt gacaggcgag agacggatgc agtctggctt ggcacgcaaa accacagcgc    720

cctggtaacc gagancacgg tcgtcccctt tcttccnggt catcctgagt actcatncac    780

acgaaatcag ggcagacaga aagtagctcg gttcaacgcc catgagttng ccacgctggt    840

cattgacatt ctcagtgacg ccagaagaga cggcaaggca gtcccctctc cgggtcaaag    900

aacatgtgga gctcatactg aaaaccatca ttaccagccc ggcgttaaag tcaagacaac    960

gatcacccga ctatgacggc gggcattaaa cgagacccag aattgggaac ccttgaaaca   1020

aaacaaccgg aaaaattggt ttggaaaatg gctattttgg gaaggggcac cccctttggg   1080

ggattttccc aaaaggggcc ttcaaaaaaa aattgaaagc cccccaaaaa aaaaaaaggg   1140

ggccccgccc cctgggcccc aaaataggtg ggacccccgg gaaaacccca aaaccccaac   1200

ccccggtgtt tttacaaccc ccggcccgcg gggttttttt ttgaaaaccc cctctcgggg   1260

atattgccgg gaagaataag gagaaaaacc tgtacccccg tttatcccgc gggaaaaaaa   1320

tgtgttttcc tctgcacaaa acccaccggt gttttcttct taaaaaaaaa aaaattcctc   1380

tttcctcccc ccgcgcccct aaaaaaaaga ggggggggcc tccccc                  1426


<210>  65
<211>  929
<212>  DNA
<213>  Homo sapiens

<400>  65
catcaccatc accatcacgg atcctattta ggtgacacta tagaatcgtc gacccacgcg     60

tccgagctcg cctccttcca ctccacctcc aagggctaca tgggcgagtg tggttacaga    120

ggaggctaca tggaggtgat caacctgcac cctgagatca agggccagct ggtgaagctg    180

ctgtcggtgc gcctgtgccc cccagtgtct gggcaggccg ccatggacat tgtcgtgaac    240

cccccggtgg caggagagga gtcctttgag caattcagcc gagagaagga gtcggtcctg    300

ggtaatctgg ccaaaaaagc aaagctgacg gaagacctgt ttaaccaagt cccaggaatt    360

cactgcaacc ccttgcaggg ggccatgtac gccttccctc ggatcttcat tcctgccaaa    420

gctgtggagg ctgctcaggc ccatcaaatg gctccagaca tgttctactg catgaagctc    480

ctggaggaga ctggcatctg tgtcgtgccc ggcagtggct ttgggcagag ggaaggcact    540

taccacttca ggatgactat cctccctcca gtggagaagc tgaaaacggt gctgcagaag    600

gtgaaagact tccacatcaa cttcctggag aagtacgcgt gaggacgcct gagccccagc    660

gggagacctg tccttggctc ttcctcccaa tgcccgtcag gctgaactcg cctcccccgt    720

gactctgcct cgggcctcgc agaggccgct ggtcacttcg tcatcatttt gcccctggag    780

acgtctttct ttgtgccttg atgttgagag cgcctctctt ttgagcaaac aagcattcta    840

tatgcaacca gagtagaggg gacctgctca gcaggtgtga ccagggttct ctgaatctgt    900

tattgttttt gcttctggaa agttcattt                                      929


<210>  66
<211>  882
<212>  DNA
<213>  Homo sapiens

<400>  66
acagggagat actatgagag gtcgcatcac catcaccatc acggatccta tttaggtgac     60

actatagaat cgtcgactct ggaccttggc tgtcactcag ttaagaagac gacgcccata    120

gaagctgctt ctagtggtgc ccgtgggctg aaggcgaaat ttgagtccat ggctgaggag    180

aagaggaagc gagaggaaga ggagaaggca cagcaggtgg ccaggaggca acaggagcga    240

aaggctgtga caaagaggag ccctgaggct ccacagccag tgatagctat ggaagagcta    300

gcagtaccgg ccccactgcc caagaaaatc tcctcagagg cctggcctcc agttgggact    360

cctccatcat cagagtctga gcctgtgaga accagcaggg aacacccagt gcccttgctg    420

cccattaggc agactctccc ggaggacaat gaggagcccc cagctctgcc ccctaggact    480

ctggaaggcc ttcaggtgga ggaagagcca gtgtacgaag cagagcctga tcctgagcct    540

gagcctgagc ccgagcctga gcccgagcct gagaatgact atgaggacgt tgaggagatg    600

gacaggcatg atcaggagga tgaaccacag ggggactatg aggaggtgct cgagcctcga    660

gattcttcat tttcttctgc tctggatgga tcatcatgct gcccggctgg agctggagct    720

ggggctgtgg ctctggggat ctcagctgtg gctctatatg attacccacg aaatgtaagt    780

gatgagcttt cctttgatcc ggacgacgta tcactgacat tgacatggtc gacaacggct    840

ggtggcggga acttgcccat gccacattgg actctccctg ca                       882


<210>  67
<211>  1179
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (829)..(829)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (850)..(850)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (863)..(863)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (900)..(900)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (932)..(932)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (935)..(935)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (947)..(947)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (962)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (967)..(967)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (989)..(989)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (992)..(992)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (999)..(999)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1004)..(1004)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1011)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1013)..(1013)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1024)..(1024)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1029)..(1029)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1039)..(1039)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1045)..(1045)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1049)..(1049)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1063)..(1063)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1068)..(1068)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1074)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1089)..(1089)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1091)..(1091)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1100)..(1100)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1107)..(1107)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1115)..(1116)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1123)..(1123)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1126)..(1126)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1130)..(1130)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1138)..(1138)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1141)..(1141)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1153)..(1154)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1167)..(1167)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1170)..(1170)
<223>  n is a, c, g, or t

<400>  67
naanagagag aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccggtgaatt ccaggatgcc tatgttctgt    120

tgagtgaaaa gaaaatttct agtatccagt ccattgtacc tgctcttgaa attgccaatg    180

ctcaccgtaa gcctttggtc ataatcgctg aagatgttga tggagaagct ctaagtacac    240

tcgtcttgaa taggctaaag gttggtcttc aggttgtggc agtcaaggct ccagggtttg    300

gtgacaatag aaagaaccag cttaaagata tggctattgc tactggtggt gcagtgtttg    360

gagaagaggg attgaccctg aatcttgaag acgttcagcc tcatgactta ggaaaagttg    420

gagaggtcat tgtgaccaaa gacgatgcca tgctcttaaa aggaaaaggt gacaaggctc    480

aaattgaaaa acgtattcaa gaaatcattg agcagttaga tgtcacaact agtgaatatg    540

aaaaggaaaa actgaatgaa cggcttgcaa aactttcaga tggagtggct gtgctgaagg    600

ttggtgggac aagtgatgtt gaagtgaatg aaaagaaaga cagagttaca gatgccctta    660

atgctacaag agctgctgtt gaagaaggca ttgttttggg agggggttgt gccctccttc    720

gatgcattcc agccttggac tcattgactc cagctaatga agatcaaaaa attggtatag    780

aaattattaa aagaacactc caaaattcca gcaatgacca ttgcctaana atgcaggtgt    840

tgaaggatcn tttgatagtt ganaaaatta tgcaaagttc ctcaaaagtt gggttatgan    900

gctatggctg ggaaattttg tgaaatatgg gnggnaaaaa ggaatcnttg accccacaaa    960

angttgngga aaactgcttt tatgggaang cngcctggng nggncctctc ngnttactac   1020

cgcnaaaant tgtagtccna aaaantccnt aaaaaaaaaa aanacccntg aaangggggc   1080

caatgaatng naatgggaan ggggtantgg gaagnnggcc atnttncaan ccccaaanaa   1140

nggctttccc ttnnaaaaga aacgggnaan ggaaacccc                          1179


<210>  68
<211>  864
<212>  DNA
<213>  Homo sapiens

<400>  68
ctatgagagg tcgcatcacc atcaccatca cggatcctat ttaggtgaca ctatagaatc     60

gtcgacccac gcgtccggcc gctgccaccg caccccgcca tggagcggcc gtcgctgcgc    120

gccctgctcc tcggcgccgc tgggctgctg ctcctgctcc tgcccctctc ctcttcctcc    180

tcttcggaca cctgcggccc ctgcgagccg gcctcctgcc cgcccctgcc cccgctgggc    240

tgcctgctgg gcgagacccg cgacgcgtgc ggctgctgcc ctatgtgcgc ccgcggcgag    300

ggcgagccgt gcgggggtgg cggcgccggc agggggtact gcgcgccggg catggagtgc    360

gtgaagagcc gcaagaggcg gaagggtaaa gccggggcag cagccggcgg tccgggtgta    420

agcggcgtgt gcgtgtgcaa gagccgctac ccggtgtgcg gcagcgacgg caccacctac    480

ccgagcggct gccagctgcg cgccgccagc cagagggccg agagccgcgg ggagaaggcc    540

atcacccagg tcagcaaggg cacctgcgag caaggtcctt ccatagtgac gccccccaag    600

gacatctgga atgtcactgg tgcccaggtg tacttgagct gtgaggtcat cggaatcccg    660

acacctgtcc tcatctggaa caaggtaaaa aggggtcact atggagttca aaggacagaa    720

ctcctgcctg gtgaccggga caacctggcc attcagaccc ggggtggccc agaaaagcat    780

gaagtaactg gctgggtgct ggtatctcct ctaagtaagg aagatgctgg agaatatgag    840

tgccatgcat ccaattccca agga                                           864


<210>  69
<211>  844
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (731)..(731)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (773)..(773)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (780)..(780)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (824)..(824)
<223>  n is a, c, g, or t

<400>  69
nccgatagag agatactatg agaggatgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga ctctggacct tggctgtcac tcagttacca aagaggacag    120

attccaggag ttctctaaca ttgtcatacc tctcatcaag aagaactcac ttgaaagcag    180

tggggtccgg acaaccaaaa atgaagagga gaatgaaaag gaaaaggagc tccagctgga    240

atatctgctg ggtgcctttg aaagcctggg caaagcctgg ccgcgaaacg cggagaccca    300

acgttgttat cgtcaggagc tgtgcaaact gatgtgtgaa cggctaaaac tcagcacgtg    360

gaaagtgcag ctaggagtcc tgcaatcaat gaatgccttt tttcaggggt taatgctttt    420

ggaagaagaa catgccgatc ctgaggcttt ggctgaaatt ctgcttgaaa cttgtaaatc    480

aatcacatat tctttagaaa ataagaccta ctcatctgtg agaacagaag ctttatctgt    540

gatagaattg ctgcttaaaa aacttgaaga atctaaacag tgggaatgtt tgacatctga    600

atgcagagtg ctcctaattg agtctttagc tactatggag ccagacagca gacctgaact    660

gcaggagaaa gcagcgttac tgaagaaaac acttgaaaat ctggaataaa ttagaagggg    720

aagaaacaaa ncagtgccat gttcattggg ggttgaagtg gtggtgttct ttngaaaacn    780

agtgggaaaa agtaagataa tctgtagcat gcatcattcc tggnctgaat aaaagaaaag    840

cctt                                                                 844


<210>  70
<211>  1103
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (942)..(942)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (967)..(967)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (983)..(983)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1046)..(1046)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1050)..(1050)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1067)..(1067)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1079)..(1080)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1084)..(1084)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1086)..(1089)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1099)..(1100)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1103)..(1103)
<223>  n is a, c, g, or t

<400>  70
agaaattact atgagaggat cgcatcacca tcaccattca cggatcctat ttaggtgaca     60

ctattagaat cgtcgaccca cgcgtccggg cttccccagc gaaaagaggg tcaacgcggc    120

cttctacagg cccgtgtccg tctaaagggc ggcgcccacc ctggagaggg ccgggtagaa    180

gtcctgaagg ccagcacatg gggcacagtc tgtgaccgca agtgggacct gcatgcagcc    240

agcgtggtgt gtcgggagct gggcttcggg agtgctcgag aagctctgag tggcgctcgc    300

atggggcagg gcatgggtgc tatccacctg agtgaagttc gctgctctgg acaggagctc    360

tccctctgga agtgccccca caagaacatc acagctgagg attgttcaca tagccaggat    420

gccggggtcc ggtgcaacct accttacact ggggcagaga ccagggagac ctggtactgg    480

gactctggga atataacaga ggtggtgatg agtggagtgc gctgcacagg gactgagctg    540

tccctggatc agtgtgccca tcatggcacc cacatcacct gcaagaggac agggacccgc    600

ttcactgctg gagtcatctg ttctgagact gcatcagatc tgttgctgca ctcagcactg    660

gtgcaggaga ccgcctacat cgaagaccgg cccctgcata tgttgtactg tgctgcggaa    720

gagaactgcc tggccagctc agcccgctca gccaactggc cctatggtca ccggcgtctg    780

ctccgattct cctcccagat ccacaacctg ggacgagctg acttcaggcc caaggctggg    840

cgccactcct gggtgtggca cgagtgccat gggcattacc acagcatgga catcttcact    900

cactatgata tcctcacccc aaatggcacc aaggtggctg anggccacaa agctagtttc    960

tgtctcnaaa aactgantgt cangagnatg tctccaaccg gtatgagtgt gccaactttn   1020

gaaaacaagg catcnctgtg ggttgntggn atctctaccg gcatganatt nactgtcann   1080

ggantnnnnt cccggatgnn aan                                           1103


<210>  71
<211>  3097
<212>  DNA
<213>  Homo sapiens

<400>  71
atggcaccgg atctgccgga aatgctggat ctggcaggca cccgtagccg tctggcaagc     60

gttagcgcag atgcagaagt tgcacgtcgt aaaagcgttc cgagcgaaac cgttgttgaa    120

gatagccgta ccggtctgcc tccggttacc gatgaaaacc atgtgattgt gaaaaccgat    180

agccagctgg aagatctggg ttattgcgtg tttaataaat ataccgttcc gctgccgtca    240

ccggttcagg atagcgaaaa tctgagcggt gaaagcggca ccttttatga aggcaccgat    300

gataaagttc gtcgtgatct ggcaaccgat ctgagcctga ttgaagttaa actggcagca    360

gcaggtcgtg ttaaagatga gtttagcgtg gataaagaag caagcgcaca tattagcggt    420

gataaaagcg gtctgagcaa agagttcgat caggaaaaaa aagcaaacga tcgtctggat    480

accgttctgg aaaaaagcga agaacatgcc gatagcaaag aacatgccaa aaaaaccgaa    540

gaagcaggcg acgaaattga aacctttggt ctgggtgtta cctatgaaca ggcactggca    600

aaagatctga gcattccgac cgatgcaagc agcgaaaaag cagaaaaagg tctgagcagc    660

gttccggaaa ttgcagaagt tgaaccgagc aaaaaagttg aacagggtct ggattttgca    720

gttcagggtc agctggatgt gaaaattagc gattttggtc agatggcaag cggtctgaat    780

attgatgatc gtcgtgcaac cgaactgaaa ctggaagcaa cccaggatat gaccccgagc    840

agcaaagcac cgcaggaagc agatgcattt atgggtgttg aaagcggtca tatgaaagaa    900

ggcaccaaag ttagcgaaac cgaggttaaa gaaaaagttg ccaaaccgga tctggttcat    960

caggaagccg ttgataaaga agaaagctac gaaagcagcg gtgaacatga aagcctgacc   1020

atggaaagcc tgaaagccga tgaaggtaaa aaagaaacct ctccggaaag cagcctgatt   1080

caggatgaaa ttgccgttaa actgagcgtt gaaattccgt gtccgcctgc agttagcgaa   1140

gcagatctgg ccaccgatga acgtgcagat gtgcagatgg aatttattca gggtccgaaa   1200

gaagaatcta aagagacacc ggatattagc attaccccgt ctgatgttgc agaaccgctg   1260

catgaaacca ttgttagcga accggcagaa attcagagcg aagaagaaga aattgaagcc   1320

cagggcgaat atgataaact gctgtttcgt agcgataccc tgcagattac cgatctgggt   1380

gttagcggtg cacgtgaaga atttgttgaa acctgcccga gcgaacacaa aggtgttatt   1440

gaaagcgtgg tgaccatcga agatgatttt attaccgttg ttcagaccac caccgatgaa   1500

ggtgaaagcg gtagccatag cgttcgtttt gcagcactgg aacagccgga agttgaacgt   1560

cgtccgtcac cgcatgatga agaagaattt gaggttgaag aagcagcaga agcacaggca   1620

gaaccgaaag atggttctcc ggaagcaccg gcatctccgg aacgtgaaga agttgcactg   1680

agcgaatata aaaccgaaac ctatgacgat tataaagacg aaaccaccat cgatgatagc   1740

attatggatg cagatagcct gtgggttgat acccaggatg atgatcgtag cattatgacc   1800

gaacagctgg aaaccattcc taaagaagag aaagccgaaa aagaagcacg tcgtagcagc   1860

ctggaaaaac atcgtaaaga aaaaccgttt aaaaccggtc gtggtcgtat tagcacaccg   1920

gaacgtaaag ttgcaaaaaa agaaccgagc accgttagcc gtgatgaagt tcgtcgcaaa   1980

aaagccgtgt ataaaaaagc cgaactggcg aaaaaaacag aagttcaggc acatagcccg   2040

agccgtaaat ttattctgaa accggcaatt aaatataccc gtccgaccca tctgagctgt   2100

gttaaacgta aaaccaccgc agccggtggt gaaagcgcac tggcaccgag cgtttttaaa   2160

caggccaaag ataaagtttc tgatggtgtg accaaatctc cggaaaaacg tagctctctg   2220

cctcgtccga gcagcattct gcctccgcgt cgtggtgttt ctggtgatcg tgatgaaaat   2280

agctttagcc tgaatagcag cattagcagc agcgcacgtc gtaccacccg tagcgaaccg   2340

attcgtcgtg caggtaaaag cggcaccagc accccgacca caccgggtag caccgcaatt   2400

acaccgggta cacctccgag ctatagcagc cgtactccgg gtacaccagg cactccgagc   2460

tatccgcgta caccgcatac ccctggcacc ccgaaaagcg caattctggt gccgagcgaa   2520

aaaaaagttg caattatccg tacccctccg aaatctccgg caaccccgaa acagctgcgt   2580

ctgatcaatc agccgctgcc ggatctgaaa aacgtgaaaa gcaaaattgg cagcaccgat   2640

aacattaaat atcagccgaa aggtggtcag gttcagattg tgaccaaaaa aatcgatctg   2700

agccatgtta ccagcaaatg tggcagcctg aaaaatattc gtcatcgtcc gggtggtggt   2760

cgtgtgaaaa ttgaatccgt gaaactggat tttaaagaga aagcacaggc aaaagttggt   2820

agcctggata atgcacatca tgttccgggt ggcggtaatg ttaaaatcga cagccagaaa   2880

ctgaattttc gtgaacatgc aaaagcacgt gttgatcatg gtgcagaaat tattacccag   2940

tctccgggtc gtagcagcgt tgcatctccg cgtcgtctga gcaatgttag cagctctggt   3000

agcattaatc tgctggaatc tccgcagctg gcaaccctgg cagaagatgt taccgcagca   3060

ctggccaaac agggactgta agcggccgct taattaa                            3097


<210>  72
<211>  1148
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (921)..(921)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (927)..(927)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (937)..(937)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (951)..(951)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (958)..(958)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (972)..(972)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (980)..(980)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1014)..(1014)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1021)..(1021)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1025)..(1025)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1041)..(1041)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1050)..(1050)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1060)..(1060)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1068)..(1072)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1085)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1090)..(1090)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1099)..(1099)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1109)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1132)..(1132)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1141)..(1141)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1147)..(1147)
<223>  n is a, c, g, or t

<400>  72
attagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc ggagagactg cggcgggagg gccaggccgt    120

gggagagacg cgggaaagtg cgggtcgcag aggcacttga ccaccccgcc ctaggccgac    180

ccggcggacg cggcgtctgg tcccaggtct ccccgctgcg ctgcttgagg ctcagccatg    240

gcccagcaga gagccctgcc ccagagcaag gagacgctgc tgcagtccta caacaagcgg    300

ctgaaggacg acattaagtc catcatggac aacttcaccg agatcatcaa gaccgccaag    360

attgaggacg agacgcaggt gtcacgggcc actcagggtg aacaggacaa ttacgagatg    420

catgtgcgag ccgccaacat cgtccgagcc ggcgagtccc tgatgaagct ggtgtccgac    480

ctcaagcagt tcctgatcct caatgacttc ccctccgtga acgaggccat tgaccagcgc    540

aaccagcagc tgcgcacact gcaggaggag tgcgaccgga agctcatcac gctgcgagac    600

gagatctcca ttgacctcta cgagctggag gaggagtatt actcgtccag ctcaagcctt    660

tgcgaagcta atgacctgcc tctgtgcgaa gcttacggga ggctggacct cgacacagac    720

tctgctgatg gcctctcggc ccctctgctg gcatccccgg agcccagtgc tggcccccta    780

caggtggcag cccctgccca ctcccatgct ggtggccctg gccccactga gcacgcctga    840

gcctccgggg ccacgcttcg ttctcaggaa caaaacctga ggcagcccct ttggatgccc    900

tcacagcctt gcttctctca ncctagnttc ccatttnggg gacttcagga ncccaaancc    960

cctaggactt tnttgggaan cccgttnncc ccagggtggg tccccnccag gaanagtagg   1020

naaanaattt tttttcctta nccattttcn aaaaacccan tcatttcnnn nncatcatct   1080

tnnnntttgn tgcccttcng ggccagccnn gggggaaaaa aaattttcca anctaggttt   1140

nggcccnt                                                            1148


<210>  73
<211>  867
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (623)..(623)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (675)..(675)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (711)..(711)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (716)..(716)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (736)..(736)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (754)..(754)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (772)..(772)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (783)..(783)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (795)..(795)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (832)..(832)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (837)..(837)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (843)..(843)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (845)..(845)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (849)..(850)
<223>  n is a, c, g, or t

<400>  73
ttcattaaag aggagaaatt aactatgaga ggatcgcatc accatcacca tcacggatcc     60

tatttaggtg acactataga atcgtcgacc cacgcgtccg gtgagaagga gaaggagcgg    120

ctgggaggcg gtttgggagt ggcgggtggt aacagcacac gagagcggct gctgtctgcg    180

cttgaggact tggaggtcct gtctagggaa cttatagaaa tgctggcaat ttcaagaaac    240

caaaagttgt tacaggctgg agaggaaaac caggtcctgg agttgttaat tcaccgagat    300

ggggaatttc aagaactaat gaaattggca cttaatcagg gaaaaattca tcatgaaatg    360

caagttttag aaaaagaagt agagaagaga gacagtgata ttcagcagct acaaaaacag    420

ctaaaggaag cagaacaaat actggcaaca gctgtttacc aagcgaagga gaaactcaag    480

tcaatagaaa aagcaagaaa aggtgctatc tcctctgaag aaataattaa gtatgcacat    540

aggatcagtg caagtaatgc tgtatgtgct ccactgacct gggttccagg ggacccccgg    600

gagaccctac ccaactgatt tanagatgag aagtgggtta ctgggtcaga tgaacaatcc    660

ttccactaat ggcgngaatg gccatttacc aggagatgca ctttgcagca nggaanattg    720

ccaaatgtcc ttgctncaca gtatccatgg cagncaaatg acatgtcgat gnatttgtta    780

ccnccaaatc atagnaggga ctttttggtg gaacctcctg ggcataataa anaaaangga    840

aangntgtnn aaattttgtc aacggga                                        867


<210>  74
<211>  948
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (900)..(900)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (924)..(924)
<223>  n is a, c, g, or t

<400>  74
atngagnaat tactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg agcaggaccc gaagcctaaa ttccaggagg    120

gtgagcgagt gctgtgcttt catgggcctc ttctttatga agcaaagtgt gtaaaggttg    180

ccataaagga caaacaagtg aaatacttca tacattacag tggttggaat aaaaattggg    240

atgaatgggt tccggagagc agagtactca aatacgtgga caccaatttg cagaaacagc    300

gagaacttca aaaagccaat caggagcagt atgcagaggg gaagatgaga ggggctgccc    360

caggaaagaa gacatctggt ctgcaacaga aaaatgttga agtgaaaacg aaaaagaaca    420

aacagaaaac acctggaaat ggagatggtg gcagtaccag tgagacccct cagcctcctc    480

ggaagaaaag ggcccgggta gatcctactg ttgaaaatga ggaaacattc atgaacagag    540

ttgaagttaa agtaaagatt cctgaagagc taaaaccgtg gcttgttgat gactgggact    600

taattaccag gcaaaaacag ctcttttatc ttcctgccaa gaagaatgtg gattccattc    660

ttgaggatta tgcaaattac aagaaatctc gtggaaacac agataataag gagtatgcgg    720

ttaatgaagt tgtggcaggg ataaaagaat acttcaacgt aatgttgggt acccagctac    780

tctataaatt tgagagacca cagtatgctg aaattcttgc agatcatccc gatgcaccca    840

tgtcccaggt gtatggagcg ccacatctcc tgagattatt tgtacgaatt ggagcaatgn    900

tggcttatac acctctggaa tganaagagc cttgctttat tactcaat                 948


<210>  75
<211>  912
<212>  DNA
<213>  Homo sapiens

<400>  75
cgcatcacca tcaccatcac ggatcctatt taggtgacac tatagaatcg tcgacccacg     60

cgtccgtgca ggctgtgaga aacgcggggt cgcggttcct gcggtcctgg acttggcccc    120

agacagccgg cagggtcgtg gccagaacgc cggccgggac catctgcaca ggcgctcgac    180

agctccaaga cgctgcggcc aagcagaaag ttgaacagaa cgcggctccc agccacacca    240

agttcagcat ttaccctccc attccaggag aggagagctc tctgaggtgg gcaggaaaga    300

aatttgagga gatcccaatt gcacacatta aagcatccca caacaacaca cagatccagg    360

tagtctctgc tagtaatgag ccccttgcct ttgcttcctg tggcacagag ggatttcgga    420

atgccaagaa gggcacaggc atcgcagcac agacagcagg catagccgca gcggcgagag    480

ctaaacaaaa gggcgtgatc cacatccgag ttgtggtgaa aggcctgggg ccaggacgct    540

tgtctgccat gcacggactg atcatgggcg gcctggaagt gatctcaatc acagacaaca    600

ccccaatccc acacaacggc tgccgcccca ggaaggctcg gaagctgtga tgggaaggag    660

gcctgcactt ggacctgacc tcaagcctca gctccagtgg gaccttgtaa aatgctccct    720

gtcagagctc tccagaatat gcttgttgga gatccttcag gcagtaaggg agagttttgc    780

ctccttacac agtggccttt gcttgcacct ccagctggag atgggtgtgc cccagaagta    840

agctttgcat ctcttacaag aggggagcta caggggcagc cgtggcctag cccaaactct    900

gctctgagaa at                                                        912


<210>  76
<211>  1072
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (768)..(768)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (861)..(861)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (870)..(870)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (874)..(874)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (877)..(877)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (906)..(906)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (922)..(922)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (927)..(927)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (969)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (978)..(978)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (983)..(983)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (991)..(991)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1014)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1024)..(1024)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1037)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1044)..(1044)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1047)..(1047)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1049)..(1049)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1054)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1065)..(1065)
<223>  n is a, c, g, or t

<400>  76
tagaggaaat tactatgaag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc ggtttaaagg aggaaactgc ttattggaag    120

gaactttcct tgaagtataa gcaaagcttc caggaagctc gggatgagct agttgaattc    180

caggaaggaa gcagagaatt agaagcagag ttggaggcac aattagtaca ggctgaacaa    240

agaaatagag acttgcaggc tgataaccaa agactgaaat atgaagtgga ggcattaaag    300

gagaagctag agcatcaata tgcacagagc tataagcagg tctcagtgtt agaagatgat    360

ttaagtcaga ctcgggccat taaggagcag ttgcataagt atgtgagaga gctggagcag    420

gccaacgacg acctggagcg agccaaaagg gcaacaatag tttcactgga agactttgaa    480

caaaggctaa accaggccat tgaacgaaat gcatttttag aaagtgaact tgatgaaaag    540

gaatctttgt tggtctctgt acagaggtta aaggatgaag caagagattt aaggcaagaa    600

ctagcagttc gggaaagaca acaggaagta actagaaagt cggctcctag ctctccaact    660

ctagactgtg aaaagatgga ctccgccgtc caagcatcac tttctttgcc agctacccct    720

gttggcaaag gaacggagaa cacttttcct tcaccgaaag ctataccnaa tggttttggt    780

accagtccac taaactccct ctgctaggat atcagcccta aacatcgtgg ggggatctct    840

tacggaaagt aggggcttta naatcccaan ttancanctt gcaggaattt tgccaaggac    900

ccagcntccc gaaaatccta tntttcnggg aatgttaact ggggggggct gaatggcaat    960

ggccccaant tctccccnat cangggcata natcttttct tccacaaagg ggcnntaaac   1020

cggnttttga ccccncnncn cccnccncng ggnnggggtc ccccncggtc cc           1072


<210>  77
<211>  1157
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (66)..(67)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (853)..(853)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (899)..(899)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (973)..(973)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (981)..(981)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (985)..(985)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (991)..(991)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1007)..(1007)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1012)..(1012)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1027)..(1027)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1047)..(1047)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1051)..(1051)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1061)..(1061)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1063)..(1063)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1067)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1085)..(1086)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1095)..(1095)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1103)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1111)..(1111)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1113)..(1113)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1122)..(1122)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1152)..(1153)
<223>  n is a, c, g, or t

<400>  77
gagaaattac tatgagagga tcgcatcacc atcaccatca cggatcctat ttaggtgaca     60

ctatannaat cgtcgaccca cgcgtccgcc atggcggagc tgcaggaggt gcagatcaca    120

gaggagaagc cactgttgcc aggacagacg cctgaggcgg ccaagactca ctctgtggag    180

acaccatacg gctctgtcac tttcactgtc tatggcaccc ccaaacccaa acgcccagcg    240

atccttacct accacgatgt gggactcaac tataaatctt gcttccagcc actgtttcag    300

ttcgaggaca tgcaggaaat cattcagaac tttgtgcggg ttcatgtgga tgcccctgga    360

atggaagagg gagcccctgt gttccctttg ggatatcagt acccatctct ggaccagctt    420

gcagacatga tcccttgcgt cctgcagtac ctaaatttct ctacaataat tggagttggt    480

gttggagctg gagcctacat cctggcgaga tatgctctta accacccgga cactgttgaa    540

ggtcttgtcc tcatcaacat tgatcccaat gccaagggtt ggatggattg ggcagcccac    600

aagctaacag gcctcacctc ttccattccg gagatgatcc ttggacatct tttcagccag    660

gaagagctct ctggaaattc tgagttgata caaaagtaca gaaatatcat tacacatgca    720

cccaacctgg ataacattga attgtactgg aacagctaca acaaccgccg agacctgaac    780

tttgagcgtg gaggtgatat caccctcagg tgtcctgtga tgctggtggt aggagaccaa    840

gcacctcatg aanatgcagt gatggctgac tccggaggtc agcccccagc tgaactcanc    900

caggcaagct gaccgaggcc ttcaagtact tcctgcaggg catgggctac atggcctcat    960

cctgcatgac tcncctgtcc nggtntcgta nagcctctct gaccaangca ancatccgtt   1020

gatgggnaac cgggncccgc ttctccnacc nggtccaaaa nancgannnn nggaaatttt   1080

ttttnngggc ccccnggggc annccntgga ngncccccgg tnaaaggccc tgtttcccaa   1140

aaaggggaac cnncccc                                                  1157


<210>  78
<211>  1575
<212>  DNA
<213>  Homo sapiens

<400>  78
accaaaagcc ctccggcaga agaagcagca agtccggaaa aagaagcaaa aagtccggtt     60

aaagaagaag ccaaatcacc ggcagaagca aaatcacctg aaaaagaaga agcgaaaagc    120

cctgcagaag ttaaatctcc ggaaaaagca aaaagcccag caaaagaaga ggcaaaatct    180

cctccggaag ccaaaagtcc tgagaaagag gaagctaaat ctccagccga agttaaaagc    240

cctgaaaaag cgaaatctcc tgccaaagag gaagccaaga gtccggctga agccaaatcc    300

ccagagaaag ccaaatctcc ggtgaaagaa gaggcgaaga gtccagccga agcgaaatca    360

cccgttaaag aggaagcgaa gtcccctgcg gaagtgaaaa gtccagaaaa agctaaaagt    420

ccgaccaaag aagaagcaaa gtcgcctgag aaagcaaagt ctccagaaaa agaggaagca    480

aagagcccag aaaaagcaaa atcaccggtt aaagccgaag caaaatctcc cgagaaagcg    540

aaaagtcccg tgaaagctga ggccaaatct cctgaaaagg ccaaatcccc tgttaaagaa    600

gaagctaaaa gtcccgaaaa agccaagagc ccagtgaaag aggaagcgaa atcaccggaa    660

aaagcgaaat ccccagtgaa agaagaagca aagactccgg aaaaggccaa gagtcctgtc    720

aaagaagagg ccaagtcccc agaaaaggcg aaaagcccag agaaggcaaa aaccctggat    780

gttaaaagtc cggaagcaaa aacccctgcg aaagaagaag cacgtagtcc ggcagataaa    840

tttccagaga aagctaagtc ccctgtcaaa gaggaagtta agtcgccaga gaaggctaaa    900

tcaccactga aagaggatgc aaaagcaccc gagaaagaaa ttccgaaaaa agaagaggtg    960

aaatcgcctg taaaagaaga ggaaaaaccg caagaggtca aagttaaaga gcctccgaaa   1020

aaagccgaag aagaaaaagc accggcaacc ccgaaaaccg aagagaaaaa agactcgaag   1080

aaagaagagg caccgaaaaa agaggctccg aaaccgaaag tggaagaaaa aaaagaacct   1140

gcagtggaaa agccgaaaga aagtaaagtg gaagctaaga aagaagaagc cgaagataaa   1200

aaaaaagtgc cgaccccaga aaaagaagct ccggcaaaag ttgaagttaa agaagatgcg   1260

aaacctaaag aaaaaaccga ggtggccaaa aaagaaccgg atgatgcaaa agccaaagaa   1320

ccgagcaaac cggctgaaaa aaaagaggca gcaccggaaa aaaaagacac caaagaggaa   1380

aaagccaaaa aacctgaaga gaagccgaaa acagaagcca aagcgaaaga agatgataaa   1440

accctgagca aagaaccgtc aaaaccgaaa gcagaaaaag ccgaaaaatc aagcagcacc   1500

gatcagaaag atagcaaacc gccagaaaaa gccaccgaag ataaagcagc caaaggcaaa   1560

taagcggccg cttga                                                    1575


<210>  79
<211>  638
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (51)..(51)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (221)..(221)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (263)..(263)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (279)..(279)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (301)..(301)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (306)..(306)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (310)..(310)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (326)..(326)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (383)..(383)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (395)..(395)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (405)..(405)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (409)..(409)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (427)..(427)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (429)..(429)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (444)..(444)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (448)..(449)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (458)..(458)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (460)..(460)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (462)..(462)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (484)..(484)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (487)..(487)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (495)..(495)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (507)..(507)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (509)..(509)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (512)..(512)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (516)..(516)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (521)..(521)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (536)..(536)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (543)..(544)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (549)..(549)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (575)..(575)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (577)..(577)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (594)..(594)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (597)..(597)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (601)..(601)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (605)..(605)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (607)..(607)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (617)..(617)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (626)..(626)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (631)..(631)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (633)..(633)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (636)..(636)
<223>  n is a, c, g, or t

<400>  79
ntagagagat tactatgaga ggatcgcatc accactcacc atcacggatc ntatttaggt     60

gacactatag aatcgtcgac ccacgcgctc cgcaggcgcc gccgggacgg gcacgggcgc    120

gcgggctccg gcgggcgccg gctgccttcc tccgtcgctc gctgtctctc ccggccgcat    180

tctcctccgc tgcggggccg agctctcccc agcgctcgca ngaaggaaga agggagccga    240

ggacgccgag aagttcccgc ggnagccgcg gatcccggnc aaggcggagg ctgcggctcc    300

nacggngcan gagcgcgatc cacggngagg ggcgtacggc caaagggtcc gcggcgtgga    360

gcgctcggac cttccgctct ccnccgggcg tgggncggga ccccntgana cgcgcccacg    420

aggggcncna gattcctaac ttgngcgnng ctaggcgnan gnaggtgttg cagccgccgg    480

agancanata gctgncggca tgatgantnt gnagcnagaa nttgaacttg gcgtcngaag    540

cgnncgccnc ggattccccc gtaggagctg ggtcncnaag ggaatgtgtt cgcngtnaat    600

ncccntngat tggcctnagc cattcnacag ncnccnac                            638


<210>  80
<211>  878
<212>  DNA
<213>  Homo sapiens

<400>  80
ctatgagagg atcgcatcac catcaccatc acggatccta tttaggtgac actatagaat     60

cgtcgaccca cgcgtccgcc caggccccag cccagcagga cctgcagggg acgagccagc    120

cgagagccca tcggagaccc caggcccccg cccagcagga cctgcagggg acgagccagc    180

cgagagccca tcggagaccc caggcccccg cccggcagga cctgcagggg acgagccagc    240

cgagagccca tcggagaccc caggccccag cccggcagga cctacaaggg atgagccagc    300

cgagagccca tcggagaccc caggcccccg cccggcagga cctgcagggg acgagccagc    360

cgagagccca tcggagaccc caggcccccg cccggcagga cctgcagggg acgagccagc    420

cgagagccca tcggagaccc caggccccag cccggcagga cctacaaggg atgagccagc    480

caaggcgggg gaggcagcag agttgcagga cgcagaggtg gagtcttctg ccaagtctgg    540

gaagccttaa ggaaaggagt gcccgtcggc gtcttggtcc tcctgtccct gctgcagggg    600

ctggggcctc cggagctgct gcgggctccc ctcaggctct gcttcgtgac ccgtgaccca    660

tgacccacag tgctggcctc ctgtggggcc actatagcag ccaccagaag ccgcgaggcc    720

ctcagggaag cccaaggcct gcagaagcct cctggcctgg ctgtgtcttc cccacccagc    780

tctcccctgc gcccctgtct ttgtaaattg acccttctgg agtggggggc ggcgggcagg    840

gctgcttttc ttagtctgat accaagcaag gccttttc                            878


<210>  81
<211>  1189
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (859)..(859)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (919)..(919)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (938)..(938)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (981)..(981)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1031)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1034)..(1034)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1047)..(1047)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1053)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1055)..(1055)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1057)..(1057)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1064)..(1064)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1068)..(1068)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1073)..(1073)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1084)..(1085)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1090)..(1090)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1092)..(1092)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1094)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1099)..(1099)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1105)..(1105)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1107)..(1107)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1116)..(1116)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1124)..(1126)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1142)..(1142)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1147)..(1147)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1153)..(1153)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1158)..(1158)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1165)..(1165)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1171)..(1171)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1176)..(1176)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1178)..(1179)
<223>  n is a, c, g, or t

<400>  81
tagagagaat tactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg ctggagacaa tgggaggatg atttgctcta    120

ttcaagataa cctccctttt ttcctgaaac cgaccttcaa gaactttttc actctagttt    180

ctgaaaaagc actggacaga gagagccaag ccgagtacaa catcacgatc accgtcacag    240

acttggggac acccaggctg aaaaccgagt acaacataac cgtgctgctc tctgacgtca    300

atgacaacgc ccccaccttc acccaaacct cctacaccct gttcgtccgc gagaacaaca    360

gccccgccct gcacatcggc agcgtcagcg ccacagacag agactcaggc accaacgccc    420

aggtcaacta ctcgctgctg ccgccccagg accggcacct gcccctcgcc tccttggtct    480

ccatcaacgc ggacaatggc cacctgtttg ccctcaggtc gctggactac gaggccctac    540

aggagttcga gtttcgcgtg ggcgccacag accgcgggtc cccggcgttg agcagcgagg    600

cgctggtgcg agtgctggtg ctggacgcca acgacaactc gcccttcgtg ctgtacccgc    660

tgcagaacgg ctccgcgccc tgcaccgagc tggtgccccg ggcggccgag ccgggctacc    720

tggtgaccaa ggtggtggcg gtggacggcg actcgggcca gaacgcctgg ctgtcgtacc    780

agctgctcaa ggccacggag cccgggctgt tcggcgtgtg ggcgcacaat ggcgaggtgc    840

gcaccgccag gctgctganc gagcgcgacg cggccaagca caggctggtg gtgctggtca    900

aggacaatgg cgagcctcng cgctcggcca cgccacgntg cacgtggttc tggtgnaagg    960

tttctnccag ccctacntgc ngctccntga gggggccccg gcccangcca aggccgaatt   1020

ccctcaacgt ntanctgggg ggtggantgg ccncngngtc gtcncttntt ctntttcggg   1080

gctnntgttn cngnggggng gctgngncag aagaanaggg ggcnnngggg gttcctgtcc   1140

gngcccnaag gtnctttncc gggtntttgg nggaangnng ggcccggaa               1189


<210>  82
<211>  1342
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (922)..(922)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (933)..(933)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (999)..(999)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1012)..(1012)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1019)..(1019)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1021)..(1021)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1041)..(1041)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1053)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1055)..(1055)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1058)..(1058)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1076)..(1076)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1078)..(1078)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1090)..(1090)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1108)..(1108)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1112)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1122)..(1123)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1146)..(1147)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1163)..(1163)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1171)..(1171)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1174)..(1174)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1205)..(1206)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1210)..(1210)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1216)..(1216)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1221)..(1221)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1230)..(1230)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1235)..(1235)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1240)..(1240)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1248)..(1248)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1271)..(1271)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1284)..(1284)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1287)..(1288)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1294)..(1294)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1302)..(1302)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1320)..(1320)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1331)..(1336)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1338)..(1340)
<223>  n is a, c, g, or t

<400>  82
aatagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gattcattca gtgaggctca ctccgagttc    120

ctaaaagcag ccagcaactt gagggataac taccgatttg cacatacgaa tgttgagtct    180

ctggtgaacg agtatgatga taatggagag ggtatcatct tatttcgtcc ttcacatctc    240

actaacaagt ttgaggacaa gactgtggca tatacagagc aaaaaatgac cagtggcaaa    300

attaaaaagt ttatccagga aaacattttt ggtatctgcc ctcacatgac agaagacaat    360

aaagatttga tacagggcaa ggacttactt attgcttact atgatgtgga ctatgaaaag    420

aacgctaaag gttccaacta ctggagaaac agggtaatga tggtggcaaa gaaattcctg    480

gatgctgggc acaaactcaa ctttgctgta gctagccgca aaacctttag ccatgaactt    540

tctgattttg gcttggagag cactgctgga gagattcctg ttgttgctat cagaactgct    600

aaaggagaga agtttgtcat gcaggaggag ttctcgcgtg atgggaaggc tctggagagg    660

ttcctgcagg attactttga tggcaatctg aagagatacc tgaagtctga acctatccca    720

gagagcaatg atgggcctgt gaaggtagtg gtagcagaga attttgatga aatagtgaat    780

aatgaaaata aagatgtgct gattgaattt tatgcccctt ggtgtggtca ttgtaagaac    840

ctggagccca agtataaaga acttggcgag aagctcagca aagacccaaa tatcgtcata    900

gccaagatgg atgccacagc cnatgatgtg ccntctccat atgaagtcag aggttttcct    960

accatatact tctctccagc caacaagaag ctaaatccna aaaaatatga angggggcng   1020

ngaattaagt gattttatta nctatctaca aananaanct acaacccccc ctgtantnca   1080

ggaaaaaaan cccaaaaaaa aaaaaagncc cnggaggatc cnnaagccgt acccaacccc   1140

cctttnnaaa agaccctccc ccnaaaaggg naanccttgg ggagaacaag accctatggg   1200

aattnntccn cccggnccaa ngaaaaaggn aaaanccgan ccggtaantt tcccaacggt   1260

tctacccccg ntttggaaaa cccnccnntt tttngggttg gnaaaaattt tttgggaaan   1320

ttgggggggg nnnnnngnnn tt                                            1342


<210>  83
<211>  642
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (37)..(37)
<223>  n is a, c, g, or t

<400>  83
tcgagaaata taaaaattat ttgctttgtg agcgganaca atataataga ttaattgtga     60

gcggataaca atttacacag aattattaaa gaggagaaat taactatgag aggatcgcat    120

caccatcacc atcacggatc ctatttaggt gacactatag aatcgtcgac ccacgcgtcc    180

gactggttcc tgggccaggc aggcagctcc atcccatcaa cttggccccg gttctatgac    240

acccgctaca accaagagac accaatggag atctgcctca atggaacccc tgctctggcc    300

tacctggcga gtgcgccccc acccctgtgt ccaagtggcc gcactccaga cctgaaggct    360

ctactcaacg tggtggacaa tgcccggagt ttcatctacg tcgctgtcat gaactacctg    420

cccactctgg agttctccca ccctcacagg ttctggcctg ccattgacga tgggctgcgg    480

cgggccacct acgagcgtgg cgtcaaggtg cgcctgctca tcagctgctg gggacactcg    540

gagccatcca tgcgggcctt cctgctctct ctggctgccc tgcgtgacaa ccatacccac    600

tctgacatcc aggtgaaact ctttgtggtc cccgcggatg ag                       642


<210>  84
<211>  1379
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (6)..(7)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (616)..(616)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (635)..(635)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (936)..(936)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1294)..(1294)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1361)..(1361)
<223>  n is a, c, g, or t

<400>  84
cccccnncct agggatacta gagaggatcg catcaccatc accatcacgg tcgacccacg     60

cgtccggcca tggggaagcg acagcaccaa aaggacaaaa tgtacattac ctgtgctgaa    120

tacactcact tttatggtgg caagaagcca gatctcccac aaacaaattt tcgtcgttta    180

ccttttgacc actgcagtct ctctctgcag ccctttgtct acccagtctg cactcccgat    240

ggcatcgtct ttgacttact gaacattgtt ccatggctta agaagtacgg gaccaacccc    300

agcaatggag agaagctgga cgggaggtcc ctgatcaagc tgaacttttc caagaacagt    360

gaggggaagt accactgccc agtgctgttt accgtgttca ccaacaacac ccacatcgtg    420

gctgtgagga cgaccggcaa cgtctacgcc tatgaggcag tggaacagct aaatatcaag    480

gccaagaact tccgggacct gctgaccgac gagcccttct cccggcagga catcatcacc    540

ctccaggacc ccaccaattt ggacaagttc aatgtctcta acttctatca tgtgaagaat    600

aacatgaaaa taatanaccc agatgaagag aaggncaaac aggacccttc ttattatctg    660

aaaaatacca atgccgagac ccgacagacc ctgcaggact tctaccagga cgtccctacc    720

actcaaaact cctccatacc cctctcaatc ccctccccca cccaatcata cctaaaaacc    780

ccaccctacc ccctatctca aatcattctt aaaaacccac ctacactccc tctatattcc    840

cctaacatac ccctcccttc acctctattc ctaaatcccc acccaccacc tttttcttac    900

atacttcttc acaccactaa cacatcaact ctcccntctc ccctcccaac aatcctctac    960

ccccccctcc acctcctcta ccaaacttca cctccaccta cccacctacc caacctccat   1020

tcccctcaac acatccatcc aacctcccat atcactctac ccccaaacct cccccacacc   1080

accaccatca cctatccacc catctcttct cactcccccc tacccaccct cctccacccc   1140

ctaccaacct cccctcactc cctctcttta ccacccaacc ccccctctac ttccaccctc   1200

cacctccctc actcatccct acacccctat cccttctata ttcaccttac tctccacact   1260

atcctatctc tcaacctcct tcatttcccc ccantctacc cactttcttc ccttcctacc   1320

ccactcacct tctaccacac tacacccctc tctccctcat nctcaacccc caacctacc    1379


<210>  85
<211>  762
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (638)..(638)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (656)..(656)
<223>  n is a, c, g, or t

<400>  85
ttnactatga gaggatcgca tcaccatcac catcacggat cctatttagg tgacactata     60

gaatcgtcga cccacgcgtc cgatgccttg gttaatcaag atattctcga aaataaagaa    120

agctgggata agattttagc ccttgttcct gaaacaattc atgatgaact tcaacaaagc    180

ttccaaaagt ctcacaattc acttcagcgt tgggagcact tgaagaaagt agccagcaga    240

tatcagaata acatcaaaaa tgacaaatat ggaccctggc tggagtggga gattatgctc    300

cagtactgtt ttccacggct ggatatcaat gtcagcaaag gaatcaatca tctactgaag    360

agccctttta gtgttcatcc taaaacaggt cgcatctctg tgcctattga tttgcagaaa    420

gtggaccagt ttgatccatt tactgttccg accataagct tcatctgccg tgaattggat    480

gccatttcca ctaatgaaga ggaaaaagag gagaatgaag ctgaatctga tgtcaaacat    540

agaaccagag attataagaa gaccagtcta gcaccttatg tgaaagtttt tgaacatttt    600

cttgaaaatc tggataaatc ccgaaaagga gaacttcntt aagaagagtg atttanaaaa    660

agatttctga agacagagct cctcaaacca ttggtggata tcttctgcct tcaccacaga    720

tcaaatactt caagagccat ttaataaata tggcagaact at                       762


<210>  86
<211>  973
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (5)..(5)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (930)..(930)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (945)..(946)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (948)..(948)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (955)..(955)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (960)..(960)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (963)..(963)
<223>  n is a, c, g, or t

<400>  86
agagngaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg ccgcaaccag gcccgcgccg ccaccatgtt    120

tcgaaatcag tatgacaatg atgtcactgt ttggagcccc cagggcagga ttcatcaaat    180

tgaatatgca atggaagctg ttaaacaagg ttcagccaca gttggtctga aatcaaaaac    240

tcatgcagtt ttggttgcat tgaaaagggc gcaatcagag cttgcagctc atcagaaaaa    300

aattctccat gttgacaacc atattggtat ctcaattgcg gggcttactg ctgatgctag    360

actgttatgt aattttatgc gtcaggagtg tttggattcc agatttgtat tcgatagacc    420

actgcctgtg tctcgtcttg tatctctaat tggaagcaag acccagatac caacacaacg    480

atatggccgg agaccatatg gtgttggtct ccttattgct ggttatgatg atatgggccc    540

tcacattttc caaacctgtc catctgctaa ctattttgac tgcagagcca tgtccattgg    600

agcccgttcc caatcagctc gtacttactt ggagagacat atgtctgaat ttatggagtg    660

taatttaaat gaactagtta aacatggtct gcgtgcctta agagagacgc ttcctgcaga    720

acaggacctg actacaaaga atgtttccat tggaattgtt ggtaaagact tggagtttac    780

aatctatgat gatgatgatg tgtctccatt cctggaaggt cttgaagaaa gaccacagag    840

aaaggcacag cctgctcaac ctgctgatga acctgcagaa aaggctgatg aaccaatgga    900

acattaagtg ataagccagt ctatatatgn tattatcaaa tatgnnanaa atacngggcn    960

ccncatactg gat                                                       973


<210>  87
<211>  827
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(4)
<223>  n is a, c, g, or t

<400>  87
tnnnaggaga attaactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccggcagtgc cggtgtgggc cgcacaggct    120

gctttatcgt catcgacgcc atgcttgagc ggatcaagcc agagaagaca gtcgatgtct    180

atggccacgt gacgctcatg aggtcccagc gcaactacat ggtgcagacg gaggaccagt    240

acagcttcat ccacgaggcc ctgctggagg ccgtgggctg tggcaacaca gaagtgcccg    300

cacgcagcct ctatgcctac atccagaagc tggcccaggt ggagcctggc gaacacgtca    360

ctggcatgga actcgagttc aagcggctgg ctaactccaa ggcccacacg tcacgcttca    420

tcagtgccaa tctgccttgt aacaagttca agaaccgcct ggtgaacatc atgccctatg    480

agagcacacg ggtctgtctg caacccatcc ggggtgtgga gggctctgac tacatcaacg    540

ccagcttcat tgatggctac aggcagcaga aggcctacat cgcgacacag gggccgctgg    600

cggagaccac ggaagacttc tggcgcatgc tgtgggagaa caattcgacg atcgtggtga    660

tgctgaccaa gctgcgggag atgggccggg agaagtgtca ccagtactgg ccggccgagc    720

gctctgcccg ctaccagtac tttgtggtag atccgatggc agaatacaac atgcctcagt    780

atatcctgcg agagttcaag gtcacagatg cccgggatgg ccagtcc                  827


<210>  88
<211>  1135
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (766)..(766)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (868)..(868)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (885)..(885)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (891)..(891)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (899)..(899)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (912)..(912)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (914)..(914)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (927)..(927)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (937)..(937)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (941)..(941)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (943)..(943)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (949)..(949)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (969)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (973)..(973)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1013)..(1013)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1051)..(1052)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1065)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1074)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1078)..(1078)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1080)..(1080)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1087)..(1087)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1095)..(1095)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1097)..(1097)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1100)..(1100)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1113)..(1113)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1118)..(1118)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1131)..(1131)
<223>  n is a, c, g, or t

<400>  88
atagagaaat tactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg aggccatgta caggtcaatc cgctggctgg    120

accggtgcat tgcagcccat cagcggccgg acaagcagaa cctcttcgcc attatccagg    180

gtgggctgga cgcagatctc cgggccacct gccttgaaga gatgaccaag cgagacgtgc    240

ctggcttcgc catcgggggc ctgagcgggg gtgagagcaa gtcgcagttc tggcggatgg    300

tggcgctgag cacctctcgg ctgccgaagg acaagccccg atatctgatg ggggttgggt    360

atgttgtgga tagggaagcc agagccctac ctgtgggaag tggattcctg gggaccccct    420

accctgcttg gggaggtggc atttggggga aacggacaca ggtctgatct gaggagacta    480

ggaagacatg gctgtccctt gggggccatt ctgagggaat atggcccagt ctggggcagt    540

gtgagggttg ggaggggccc tgggaagccc ctgaggttct ctgccccctc ccgtcatggc    600

tgcaacccca gctatgccac tgatctggta gtctgcgtgg ctcttggatg tgacatgttc    660

gactgcgtct tccccacacg gacagcgcgc tttggctctg ccctggtgcc cactgggaac    720

ctgcagttga ggaagaaggt gtttgagaag gacttcggcc ccatanaccc ggagtgcacc    780

tgccccacgt gccaaaagca cagccgcgcc ttcctgcacg cactgctgca cagtgacaac    840

acggccgcgc tgcaccacct cacggtcnac aacatcgcct accanctgca nctcatganc    900

gccgtccgca cnancatcgt ggaaaancgc ttcccgnact ncntgcggna cttcatgggc    960

gccatgtang ggnatcccac cctctgtncc acttgggcca ctgannctct ggncctctgt   1020

gggaatccca ctgggcttga cctggcattg nnaaaaggaa ggaanaaaga aggnaggnan   1080

ggcctgnaaa aaaantnaan gattcctttt ttnaaagntt tttttttttt nactt        1135


<210>  89
<211>  764
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (754)..(755)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (758)..(758)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (764)..(764)
<223>  n is a, c, g, or t

<400>  89
tatagagaga tactatgaga ggtcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgactc tggaccttgg ctgtcactca gttataggtc ccggcccgag    120

cctccggccg cccgccgggt ttgtcccgcg atccccgacc atgcccgccg acctcagcgg    180

tacttggacc ctgctcagca gcgacaactt cgagggctac atgctggccc taggtattga    240

ctttgccact cgtaaaatag ccaagttgct gaagccacag aaagtgattg agcagaatgg    300

ggattctttt accatccaca cgaacagcag cctaaggaac tactttgtga aatttaaagt    360

tggagaagaa tttgatgaag ataacagagg cctggacaac agaaaatgca agagtttggt    420

tatctgggac aatgacaggc tcacctgtat ccagaaggga gaaaagaaga acagaggctg    480

gacccattgg atcgaaggag acaaactcca cctggaaatg ttctgtgaag gtcaagtgtg    540

caaacagaca ttccagagag cctgatccac atccagcagc agagcccact tgtggctgca    600

gctttatgcc aaattatatt gcagactgaa cagacgttta tctatcccat ttggcgacga    660

ggactcgtgg ctggagagag ccacacagcg tgtaacctga agtcatctag attatgggga    720

aactgctcag cttcaataaa cctgtcccaa tgannaanaa atan                     764


<210>  90
<211>  1033
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (775)..(775)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (794)..(794)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (869)..(869)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (901)..(901)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (915)..(915)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (921)..(921)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (923)..(923)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (961)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (964)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (968)..(968)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (972)..(972)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (975)..(976)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (978)..(978)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (998)..(998)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1000)..(1000)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1002)..(1002)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1010)..(1010)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1022)..(1022)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1024)..(1024)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1027)..(1027)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1030)..(1030)
<223>  n is a, c, g, or t

<400>  90
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg tcgggccgga ccttggagcg cgcgggccgg    120

cggcggcgcg agtggctcgg gagcgcggct gatcacaggg ccagaggagg cggaccggcc    180

cccttcaatg tccagtcatg atacagcctc tccagcggcc cccagccgca acccctgctg    240

cctgtgctgg tgctgctgct gtagctgctc ctggaaccaa gagcggcggc gcgcgtggca    300

ggcctcccgg gagagcaagc tgcagcccct ccccagctgt gaagtatgtg ccacgccaag    360

tcctgaggag gtgcagagct gggcgcagtc ttttgacaag ctgatgcaca gcccagcggg    420

acgcagcgtg ttccgggcgt tcctgcggac agagtacagc gaggagaaca tgctcttctg    480

gttggcctgc gaggagctga aggccgaggc caaccagcat gtggtagacg agaaggcgag    540

gctcatctac gaggactacg tatccatcct gtcccccaag gaggtgagcc tggactcccg    600

tgtgcgggag ggcatcaaca agaagatgca ggagccgtcc gcacacacgt tcgacgacgc    660

gcagctgcag atctacacgc tcatgcaccg ggactcctac ccccgcttcc tcagctctcc    720

cacctaccgt gccctgctgc tgcaggggcc atcacagtcc tcctccgagg cctangccgc    780

ccccagcagc acanaccccg ccgcctccta cggccgactc tgggttccct tcaggtgttg    840

ttgtcggcag ggctgtcagg gcacatgcnt ggccggctgg ggtccccacc ccgcggaaaa    900

nggtcctaaa cccantgggg nantgctgtg tctcctgggt tctgcccacc cgtgggccaa    960

nnangaantc cnagnngnaa gggngggcct tccaggtngn angggggggn caaaaacccc   1020

cntnatnggn ccc                                                      1033


<210>  91
<211>  839
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (652)..(652)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (696)..(696)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (758)..(758)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (815)..(816)
<223>  n is a, c, g, or t

<400>  91
atactatgag aggacgcatc accatcacca tcacggatcc tatttaggtg acactataga     60

atcgtcgact ctggaccttg gctgtcactc agttgggccc tttggcttcc tggacaggta    120

cgaccccgac cacgtgtgca atgcctccga caacaccggc cgctacgcgt acagcaagca    180

gcccgaggtg tgcaggtgga acctgcggaa gctggccgag gccctgcagc cggaactgcc    240

cctggagctg ggggaggcca tcctggccga ggagtttgac gccgagttcc aaaggcacta    300

cctgcagaag atgcgcagga agctgggcct cgtgcaggtg gagctggagg aagacggggc    360

gctggtgtcc aagctcctgg agaccatgca tctgaccggt gccgacttca caaacacctt    420

ctacttgctg agctccttcc cagtggagct agagtcgcca ggcctggcgg aattcctggc    480

caggctgatg gagcagtgtg cctccctgga ggagctgagg ctggccttcc ggccccagat    540

ggatccccgg cagctatcca tgatgctgat gctggcgcag tcaaacccgc agctgttcgc    600

gcttatgggc acccgggcag gcatcgccag ggagctggag cgtgtggagc ancagtctcg    660

gctggagcag ctgagtgcgg cagagctgca gagcangaac cagggccact gggctgactg    720

gctacaggcg tacagagccc ggctgggaca ggacctgnaa ggcgctgggg acgctgccgc    780

tggcaggctg agcacgtgcg cgtgatgcac gccanncacc cgaatacgtg ctgaggact     839


<210>  92
<211>  1234
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (743)..(743)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (750)..(750)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (775)..(775)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (807)..(807)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (810)..(810)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (828)..(828)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (831)..(831)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (834)..(834)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (854)..(854)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (870)..(870)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (874)..(874)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (904)..(904)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (930)..(930)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (933)..(933)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (937)..(937)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (946)..(946)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (963)..(963)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (968)..(968)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (970)..(970)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (972)..(972)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (991)..(991)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1014)..(1014)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1017)..(1017)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1023)..(1023)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1034)..(1034)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1038)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1044)..(1044)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1066)..(1066)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1075)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1083)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1087)..(1087)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1099)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1105)..(1105)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1117)..(1117)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1131)..(1131)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1146)..(1146)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1155)..(1155)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1158)..(1159)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1166)..(1167)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1169)..(1169)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1177)..(1177)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1184)..(1184)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1214)..(1214)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1219)..(1219)
<223>  n is a, c, g, or t

<400>  92
gagaaattac tatgagagga tcgcatcacc atcaccatca cggatcctat ttaggtgaca     60

ctatagaatc gtcgacccac gcgtccgcgg acgcgtgggc gcaaaatcat gctgccgtgt    120

tccgtgtggg aagcttgttg caagaaggtt gtgggaaaat cagcaagctc tatggagacc    180

tgaagcatct gaagacgttt gactggggaa tggtctggaa cacggacctg gtggagaccc    240

tggagctgca gaacctggtg ctgtgtgcgc tgcagaccgt caatggagca gaggcgcaga    300

aggagtcacg gggcgcgcac gccggggaag actacaaggt gcggattgat gagtacgatc    360

actccaagcc catccagggg caacagaaga agccctttga ggagtactgg aggaagcaca    420

ccctgtccta tgtggacgtc ggcactggga aggtcactgt ggaatataga cccataatcg    480

acaaaacttt gaacgaggct gactgtgcca ccgtcccccc agccattcgc tcctactgat    540

gagacaagat gcggtgatga cagaatcagc tttttgcaca gccagagaac aacacatcac    600

acacaagaaa cagttgtgct catgtgatgg gggcctcagc gctaggaagg agtggactgt    660

tggcgcacgc agcagcttga ataaatctga aagtcactac gctgcgtaag agaagccaaa    720

taaagcgcat gctgtgtaca ganggtgtcn agaatgcctc ctacgtgacg ggaancaaat    780

ccgtggttcc ctgcaaactg gcaggancan attccaaggc acaggaanaa nctngcaggt    840

aaaatgtgtt catnaccttc tgcccatttn accncaaaaa agctgggaaa aaaaatgcta    900

accnaaaaaa aaggtgaaag taaataaaan ttntcanctg ggtgantggg taaacntgca    960

ggnttgcngn cntgcttttt ttaaaaaact ngggggtaaa aggactctca tacntcnttg   1020

ggnaatgcaa aacnttcncc cccntggaaa aagatttggc accttntaan aaannaaatg   1080

gnntttnccc ttaaaccnnc aattntaaaa tccgccncaa aaaaatttgg naaaaaaaaa   1140

aaggantttt tcccnaannt tttttnncnc cccgaanggt tttntcccca aaatttttct   1200

tggggggttt tttnaaaang aaaaaaaaaa aatt                               1234


<210>  93
<211>  1053
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (858)..(858)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (901)..(901)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (911)..(911)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (932)..(932)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (934)..(934)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (936)..(936)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (961)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (967)..(967)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (971)..(971)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (974)..(974)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (979)..(979)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (983)..(983)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1007)..(1008)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1012)..(1012)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1016)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1019)..(1019)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1026)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1028)..(1028)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1038)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1041)..(1041)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1053)
<223>  n is a, c, g, or t

<400>  93
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc ggacgcgtgg gcccagagcc gaagccggca    120

ctgtgaggag ctcctcccag ggtccagcgc ctgtgctgga aacagcagcc agagccgccc    180

ctgcccctac agcgagattc ccgtcatcct gccagcctcc agcatggagg aggccaccgg    240

ctgtgcaggt aaaagaaacc ggccctacct catgctgcgg tcctcccagc cctccggcac    300

cccactccaa agtctggact ctttccacat cctgctccag acagccaagc tttgttgggg    360

tccccactgc tttgagatgg tgtgtagggt ggtctgggca gttccctcca tgcccccccc    420

agctaggagg ccatcatcag tctgtaccca aggaagagtc atctgactct agaccctctg    480

gttgccacct ctgacttgag ccacagggta ccttgtgaaa gaggtcccca gtgacagcct    540

ccccagcctc cctgtttcct ttggctgtgg cctcagagcc ctttccagga tgcctcagag    600

cctcctgttg ctgtttctgc tcccagggag gcaggcagga gtctgtcctc ttcacagtgg    660

ccctcatctt actacctgcc tctcttcccc tagggttcaa tctcatccac ttggtggcca    720

cgggcatctc ctgcttcttg ggctctgggc tcctgaccct agcagtgtac ctgtcttgcc    780

agcactgcca gcgtcagtcc caggagtcca cactggtcca tcctgccacc cccaaccatt    840

tgcactacaa gggcggangc accccgaaaa atgaaaagta cacacccatg gaattcaaga    900

ncctgaacaa naataacttg atccctgatg anananccaa cttctaccca ttgcancaaa    960

nnaatgngta nacnaatant tantaccnag ccccctgaaa aaaaaanntt tncggnccna   1020

aggctnanct ggaaaaangg ngtttcccaa aan                                1053


<210>  94
<211>  892
<212>  DNA
<213>  Homo sapiens

<400>  94
catcaccatc accatcacgg atcctattta ggtgacacta tagaatcgtc gacccacgcg     60

tccggtggca agggtctgag gcgtccccat tgtactgtgg aggagggtgt tcaaaaagag    120

gaaagagaga agtaccgaaa gttattggaa cgacttaaag aaagtggtca tggaaactct    180

gtctgtcctg taacttcaaa ttatcacagt tctcaaagaa gtcagatgga cacattaaag    240

accaaaggct ggggggaaga gcaaaatcac ggagtcaaaa caactcagtt tgttccaaaa    300

caatatagac ttgttgaaac aaggggacct ctatgttcat tgagaagtga aaagaggtgt    360

tcaaagggga aaattactga tacagagacg atggtcggaa tcagatttga aaatgaaagt    420

aggaggggat accaactgga gcctgaccta tcagaagaag tgtcggcccg actccgcctg    480

ggcagtggaa gcaatggctt actcaggagg aaagtgtcaa taattgagac aaaggaaaag    540

aattgctcag gcaaagagag ggacagaaga acggacgatc tccttgaact tacagaggac    600

atggaaaagg aaatcagtaa tgccctaggc catggcccac aggatgaaat cctaagtagt    660

gctttcaaat tgcgaattac tcgaggagat attcagacat taaagaacta tcactggctc    720

aatgatgaag tcattaattt ttacatgaat cttctggtgg aaagaataaa aagcaaggct    780

atccagcact tcatgtattc agtactttct tctatcctaa attaaagtct gggggttacc    840

aagcagtgaa acgatggacc aaaggggtaa atctctttga acaagaaatt at            892


<210>  95
<211>  810
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (706)..(706)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (755)..(755)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (758)..(758)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (793)..(794)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (803)..(803)
<223>  n is a, c, g, or t

<400>  95
aatactatga gaggacgcat caccatcacc atcacggatc ctatttaggt gacactatag     60

aatcgtcgac tctggacctt ggctgtcact cagttaagga actgggctca tccacaaatg    120

ccttgagaca gctactagga tttccatttt atggtaaacc aatgcgaata cagtatgcaa    180

aaacagattc ggatataata tcaaaaatgc gtggaacttt tgctgacaaa gaaaagaaaa    240

aagaaaagaa aaaagccaaa actgtggaac agactgcaac aaccacaaac aaaaagcctg    300

gccagggaac tccaaattca gctaataccc aaggaaattc aacaccaaat cctcaggtcc    360

ctgattaccc tccaaactat attttattcc ttaataactt accagaagag actaatgaga    420

tgatgttatc catgctgttt aatcagttcc ctggcttcaa ggaagtacgt ctggtaccag    480

ggaggcatga cattgctttt gttgaatttg aaaatgatgg gcaggctgga gctgccaggg    540

atgctttaca gggatttaag atcacaccgt cccatgctat gaagatcacc tatgccaaga    600

aataacattt gggatagtcg tctttaaaag acttggtgtt atttacagtg tttgttttga    660

taacatttgg ctgggtcatt ttaatagtta gagatgagga ggagtnaaag tgaaattttt    720

gtgaaggact taatttatca gtgtttcttt agccntgntg aactatgaaa tacgaaggcc    780

ttaattttgt acnnataact ttnattttgt                                     810


<210>  96
<211>  1179
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (221)..(221)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (258)..(258)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (311)..(311)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (314)..(314)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (860)..(860)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (896)..(896)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (906)..(906)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (923)..(923)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (928)..(928)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (969)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (973)..(973)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (991)..(991)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1008)..(1008)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1021)..(1021)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1032)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1038)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1042)..(1042)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1056)..(1056)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1064)..(1064)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1066)..(1067)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1082)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1086)..(1086)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1121)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1134)..(1134)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1137)..(1137)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1141)..(1141)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1155)..(1155)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1161)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1166)..(1166)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1168)..(1171)
<223>  n is a, c, g, or t

<400>  96
gnantagaga aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgatccctc gcttcagatt gacatacctg    120

atgcgctcag tgagagagac aaagtcaaat ttacagtgca cacaaagatt ccacctgctc    180

ctacgaagcc cgactttgat ggtcctcgag agaagatgca naaactggga gaaggtgaag    240

ggtctatgac caaagaanaa tttgccaaga tgaaacaaga actggaagct gagtatctcg    300

ctgtgtttaa naanactgtg tcctcccatg aagtctttct tcagcggctt tcttctcacc    360

ctgttctcag taaagatcgc aactttcatg ttttcctgga atatgatcag gatctaagtg    420

ttaggcggaa aaatactaaa gaaatgtttg gtggcttctt caaaagtgtg gtgaaaagtg    480

ctgatgaagt cctttttact ggagttaagg aggtagatga cttctttgag caagagaaga    540

acttccttat taactattac aataggatca aagattcttg tgtgaaagct gacaaaatga    600

ccagatctca taaaaatgtt gccgatgact atatccacac cgcagcctgc ttacatagcc    660

tggctttaga agagcccaca gtcatcaaaa agtacctatt gaaggttgct gagctatttg    720

aaaaactaag gaaagtagag ggtcgagttt catcagatga agatttgaag ctaacagagc    780

tcctccgata ctacatgctc aacattgaag ctgctaagga tctcttatac agacgcacca    840

aagccctcat tgactatgan aactcaaaca aagctctgga taaggcccgg ttaaanagca    900

aagacntcaa gttggctgag gcncccanca ggagtgctgc caaaatttga acaactttcc    960

gaatctgcna aanaaaactg aaaatttcaa ncggaanaaa gggccncntt taaaaaaatc   1020

naattgaaat gnccggancn gnaaaaaaac atgccnggaa acangnnccc ctttttgcaa   1080

anctgnattg acttgttcaa aaaaactgaa atgccctccc ncaaaaaaaa aaanganggg   1140

naaaaaaacc caccnccctn nccttnannn nttccccgg                          1179


<210>  97
<211>  673
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (531)..(531)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (541)..(542)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (556)..(556)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (558)..(559)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (575)..(575)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (580)..(580)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (583)..(583)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (595)..(595)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (600)..(600)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (612)..(613)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (615)..(615)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (617)..(617)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (625)..(625)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (630)..(630)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (636)..(636)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (644)..(644)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (646)..(646)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (651)..(651)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (655)..(655)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (663)..(663)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (666)..(666)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (669)..(673)
<223>  n is a, c, g, or t

<400>  97
taagaggaga attaactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgcccggag cacgcagccc gtgccccgct    120

tcgactgcgt gctcaagctg gtgcaccact acatgccgcc ccctggagcc ccctccttcc    180

cctcgccacc tactgaaccc tcctccgagg tgcccgagca gccgtctgcc cagccactcc    240

ctgggagtcc ccccagaaga gcctattaca tctactccgg gggcgagaag atccccctgg    300

tgttgagccg gcccctctcc tccaacgtgg ccactcttca gcatctctgt cggaagaccg    360

tcaacggcca cctggactcc tatgagaaag tcacccagct gccggggccc attcgggagt    420

tcctggacca gtacgatgcc ccgctttaag gggtaaaggg cgcaaagggc atgggtcggg    480

gagaggggac gcaggccccc tctcctccgt ggcacatggc acaagcacaa naagccaacc    540

nnggagagag tcctgnannc tctggggggg aaaanagggn ggnacagggc ccctnccctn    600

tgccttctcc cnngnanaat ggggnaaggn ggaccntgga atgngnttgg naggnaaagg    660

ggnaanacnn nnn                                                       673


<210>  98
<211>  1059
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (806)..(806)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (899)..(899)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (903)..(903)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (909)..(909)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (963)..(963)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (969)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (976)..(976)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (990)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (992)..(992)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (994)..(994)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (998)..(998)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1010)..(1010)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1013)..(1014)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1026)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1029)..(1029)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1037)..(1037)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1042)..(1042)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1045)..(1045)
<223>  n is a, c, g, or t

<400>  98
ntnagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gccgacatgg aagtcatcga gctgaacaaa    120

tgcacctcgg gccaatcctt tgaagtcatc ctgaagccac cctcctttga tggggttccc    180

gagttcaacg cctccctgcc aaggcggcga gacccatccc tggaagagat ccagaagaaa    240

ctagaagcgg ctgaggagcg aaggaagtac caggaagcgg agctcctgaa acacctagca    300

gagaaacggg aacatgagag agaggtgatc caaaaggcca ttgaggaaaa caacaacttc    360

atcaagatgg ctaaggaaaa actggcccag aagatggaat ccaacaagga gaacagggag    420

gcccacctcg ccgccatgtt ggaacggctg caagagaagg acaagcacgc cgaggaggtg    480

cggaaaaaca aggagctgaa ggaagaggcc tccaggtaaa gcctagaggc caaagaactt    540

tccaggtcag ccggacagct ccagcagctc cacgttccag gcagcctcgc ccgccggctg    600

cgctcccagc actggggttt ggggggaggg gggtggccaa ggggcgtttc ctctgctttt    660

ggtgtttgta catgttaaga attgaccagt gaagccatcc tatttgtttc cggggaacaa    720

tgacggggtg ggagagggga gaggagagag tttgggaaag ggagatggag aagaactcaa    780

ggacattgca accctgcccg gcgcanatct gattttcaca tctctacctg gacattgagc    840

ctccaggcac catgttgagg agaaatgaaa accagggcgg tagaacttca gggtgaagna    900

canaattcnt gggtggggca cggctgcagg cgcaccaaaa aacccagcca aagggggtgt    960

gantaccant ggtgtngctt ccccctgcan cngntggnat gaggtctgtn tgnngtgtgt   1020

gaaccntcnt tttttgntct cntgncccat gaaactttg                          1059


<210>  99
<211>  614
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (352)..(352)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (360)..(360)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (371)..(371)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (415)..(415)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (425)..(425)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (442)..(443)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (446)..(446)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (475)..(475)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (479)..(479)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (486)..(487)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (496)..(497)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (512)..(512)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (522)..(522)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (535)..(536)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (539)..(539)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (558)..(558)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (568)..(569)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (573)..(573)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (575)..(575)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (591)..(591)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (593)..(593)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (598)..(601)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (609)..(610)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (612)..(612)
<223>  n is a, c, g, or t

<400>  99
ntngagaaat tactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg tgaataagtc gtcctacaaa tatgaagcag    120

acacggtgga cctgaattgg tgcgtcattt ccgacatgga agtcatcgag ctgaacaaat    180

gcacctcggg ccaatccttt gaagtcatcc tgaagccacc ctcctttgat ggggttcccg    240

agttcaacgc ctccctgcca aggcggcgag acccatccct ggaagagatc cagaagaaac    300

tagaagcggc tgaggagcga aggaagtacc aggaagcgga gctcctgaac cncttagcan    360

agaaacggga ncatgagaga gagtgatcca aaggccattg aggaaaacac aactncttca    420

gatgntaaag aaaaactggc cnnaanatgg attccaccag gaaacgggag gcccnctcnc    480

cccctnnttg aaacgnngca aaaaaggaaa anccccccaa gnggggggaa aaaannggnc    540

ctttaaggaa aaaggccncc cggttaannc ctnanggccc aaaaaatttt ncnggttnnn    600

nggggaaann tncc                                                      614


<210>  100
<211>  931
<212>  DNA
<213>  Homo sapiens

<400>  100
tgagaggtcg catcaccatc accatcacgg atcctattta ggtgacacta tagaatcgtc     60

gacccacgcg tccgcccacg cgtccgcgga cgcgtgggcg aggttcctcg cggacagctc    120

agggttgctc tcttgttctg aagacatgtc catcagatac tgggatctgg acatcagtcc    180

atatagcctg tacttcgcca gcgggtccca cgaccgcacc gccaggctgt ggtcatttga    240

tcggacgtac ccgctgagga tatatgcagg acacctggca gatgtggact gtgtcaaatt    300

ccaccctaat tcaaactact tggccacggg ctcaaccgac aagaccgtcc ggctgtggag    360

cgctcagcag gggaactcgg tgaggctttt cacaggccac cgtggccccg tgctttctct    420

cgccttttct cccaacggta agtacttggc gtctgctggc gaggaccagc ggttgaagct    480

gtgggacttg gcctctggga ccctttataa agagttgaga ggccacacag acaatatcac    540

cagcctcacc ttcagtccag acagcggctt gattgcctct gcctccatgg acaactcggt    600

gcgcgtctgg gacatcagga acacttactg cagtgcacct gccgacggct cctccagcga    660

gctcgtgggc gtgtacaccg ggcagatgag caacgtcctg agcgtgcagt tcatggcctg    720

taaccttctt ctggtgactg gaattacaca agaaaatcag gaacattatt ttttaacttt    780

gttggaacgg actggggtaa cagtgggaaa gcctccagtt gcaatccttc aatgagctga    840

gattgaatca ttgactgtga aagagccccc tcctcccctc tctcctgggc cctcattccg    900

ggcaggtccc cttcactcag cccccagtgt c                                   931


<210>  101
<211>  1061
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (958)..(958)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (994)..(994)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1033)..(1033)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1057)..(1057)
<223>  n is a, c, g, or t

<400>  101
tagagagaat tactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg cccacgcgtc cgatgtaggc accggtccga    120

gtgcctgccc tctgtccccg cggctgggtc tcgtctgctc cggttcctgg gctcctaatt    180

cttggtccag cttcttccag gacaggaaaa ggaggggaaa tctcgacatg gaaaaactct    240

acagtgaaaa tgaaggaatg gcttcaaacc aaggaaagat ggaaaatgaa gaacagccac    300

aagacgagag aaagccagaa gtaacttgta ctctggaaga caagaagtta gaaaacgagg    360

gaaagacaga aaacaagggc aaaacaggag atgaggaaat gttaaaggat aaaggaaagc    420

cagagagtga gggagaggca aaagaaggaa agtcagagag ggagggagag tcagagatgg    480

agggaggatc agagagagag ggaaaaccag agatagaggg aaagccagag agtgaaggag    540

agccagggag tgaaacaagg gctgcaggaa agcgcccagc tgaggatgat gtacccagga    600

aagccaaaag aaaaactaat aaggggctgg ctcattacct caaggagtat aaagaggcca    660

tacacgatat gaatttcagc aatgaggaca tgataagaga atttgacaat atggctaagg    720

tgcaggatga gaagagaaaa agcaaacaga aattgggggc gtttttgtgg atgcaaagaa    780

atttacagga ccccttctac cctagaggtc caagggaatt caggggtggc tgcagggccc    840

cacgaaggga cattgaagac attccttatg tgtagtgtcc ctggcaggca tttaccaggc    900

catgtgcttt accgttacgg taatacttta ctttaggcat ccctcctgtt gctagcancc    960

ttttgaccta tctgcatgca gtgttctcag tagnaatgtt cctctgttac atggaaaaat   1020

tgttgatggt gcnttgtaaa ttaaaaaccc acttgcnaac c                       1061


<210>  102
<211>  882
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (720)..(720)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (759)..(759)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (761)..(762)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (769)..(769)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (803)..(803)
<223>  n is a, c, g, or t

<400>  102
agagagatac tatgagaggt cgcatcacca tcaccatcac ggatcctatt taggtgacac     60

tatagaatcg tcgactctgg accttggctg tcactcagtt agaaaccaac aaaggatttt    120

ggagcaaaat aaggaccaga aggaagccac caatactacc agtgagcctt ctgccccatc    180

tcaagatctc ctcgacctaa gtcccagtcc ccggatgcct agggccactc tgggagaact    240

caacaccatg aataatcaac tttcaggctt aaatttcagc cttccaagtt ctgatgtaac    300

aaacaactta aaacccagtc ttcatccaca gatgaacttg ctagccttgg agaatacaga    360

gatacccccg tttgcccaaa ggaccagcca aaacctcacc tcaagccacg catatgataa    420

ttttctggaa cattcaaatt cagtgtttct acagccagtt agtctacaaa ccattgcagc    480

agcaccatca aaccagagtc tgccaccttt gcccagcaat catccagcga tgacaaaaag    540

tgatctccag ccacctaatt actacgaggt aatggagttt gatcccttag ctcctgctgt    600

cactacagaa gctatttatg aagaaattga tgctcaccag cacaaaggag ctcaaaatga    660

tggtgactga gaagaaagtg gatgatcagc tcactaccac atcaaaggtg ccaactctcn    720

taaacgtaga ctctgtgcag ctttgaagcc tggaagacna nntactacna catgtcaaag    780

ccatggtggc acatttctgc tantatgaag ataaatagaa tacagttcag gatacactga    840

ttctgacaca gcgtgagatt cacagaactg ttggaacaat ac                       882


<210>  103
<211>  1381
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (849)..(849)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (867)..(867)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (883)..(883)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (904)..(904)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (954)..(954)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (957)..(957)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (964)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (971)..(971)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (975)..(975)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (981)..(981)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (994)..(994)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1007)..(1007)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1013)..(1013)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1017)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1027)..(1027)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1039)..(1039)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1052)..(1052)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1056)..(1057)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1068)..(1068)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1076)..(1076)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1092)..(1093)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1097)..(1097)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1099)..(1099)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1136)..(1136)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1138)..(1138)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1164)..(1164)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1172)..(1172)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1177)..(1177)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1195)..(1195)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1199)..(1199)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1214)..(1214)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1222)..(1222)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1230)..(1230)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1238)..(1238)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1251)..(1251)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1262)..(1262)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1264)..(1265)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1267)..(1267)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1291)..(1291)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1296)..(1297)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1304)..(1304)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1313)..(1313)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1324)..(1324)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1326)..(1327)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1334)..(1334)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1339)..(1339)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1343)..(1343)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1348)..(1348)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1354)..(1354)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1359)..(1359)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1368)..(1368)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1376)..(1376)
<223>  n is a, c, g, or t

<400>  103
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg aaagaaaaga acatttgatg aaacagtttc    120

tacatatgtg ccccttgcac agcaagttga agacttccat aaacgaaccc ctaacagata    180

tcatttgagg agcaagaagg atgatattaa cctgttaccc tccaaatctt ctgtgaccaa    240

gatttgcaga gacccacaga ctcctgtact gcaaaccaaa caccgtgcac gggctgtgac    300

ctgcaaaagt acagcagagc tggaggctga ggagctcgag aaattgcaac aatacaaatt    360

caaagcacgt gaacttgatc ccagaatact tgaaggtggg cccatcttgc ccaagaaacc    420

acctgtgaaa ccacccaccg agcctattgg ctttgatttg gaaattgaga aaagaatcca    480

ggagcgagaa tcaaagaaga aaacagagga tgaacacttt gaatttcatt ccagaccttg    540

ccctactaag attttggaag atgttgtggg tgttcctgaa aagaaggtac ttccaatcac    600

cgtccccaag tcaccagcct ttgcattgaa gaacagaatt cgaatgccca ccaaagaaga    660

tgaggaagag gacgaaccgg tagtgataaa agctcaacct gtgccacatt atggggtgcc    720

ttttaagccc caaatcccag aggcaagaac tgtggaaata tgccctttct cgtttgattc    780

tcgagacaaa gaacgtcagt tacagaagga gaagaaaata aaagaactgc agaaagggga    840

ggtggcccna gttcaaggca cttcccnttg cctcattttg acnccattaa cctgccagag    900

aaanaaggta aagaatgtga ccaaattgaa ccttttctgc ttggaaactg acanaanagg    960

tgcnctgaag nccanacttg naagccccgc tggnaaaaaa aactganacc gcnaaannaa   1020

ccgctgnttc agggtcgtnc aaaacccggt cnttcnnagg agcccttngt tccaanaaaa   1080

aaaaaaaatc anntgcngng ggcctttttg ggtttcctag ttcagaacct tttccncngg   1140

ttctggaaaa aaaacccaaa aacngcccgg ancttgnaaa aaaaaaggct gaggnaaanc   1200

ccaaaacccc cccnttgggg gnggcccccn tcgggggnaa aacaaaaaaa nggaccggcc   1260

cncnncngaa aaagggggtt agggaaccca ncccgnnccg gggnggaaaa aanaaggacc   1320

cccngnnggg gggnccccna ttnccccntt ccgngaaanc gggggggnaa ccccgngggg   1380

a                                                                   1381


<210>  104
<211>  1179
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (850)..(850)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (915)..(915)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1014)..(1014)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1038)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1056)..(1056)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1065)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1073)..(1073)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1082)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1085)..(1085)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1089)..(1089)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1092)..(1092)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1099)..(1099)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1103)..(1103)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1136)..(1136)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1138)..(1138)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1144)..(1144)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1175)..(1175)
<223>  n is a, c, g, or t

<400>  104
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc ggacgcgtgg gcggacgcgt ggggttgcct    120

ggagggcggg agggaggcgg cggaggaaga gggcgagcct gaggtgaaaa agcggcgact    180

tctgtgtgtg gagtttgcct cggtcgcaag ctgcgatgcc gcagtggctc agtgcttcct    240

ggccgagaac gactgggaga tggaaagggc tctgaactcc tacttcgagc ctccggtgga    300

ggagagcgcc ttggaacgcc gacctgaaac catctctgag cccaagacct atgttgacct    360

aaccaatgaa gaaacaactg attccaccac ttctaaaatc agcccatctg aagatactca    420

gcaagaaaat ggcagcatgt tctctctcat tacctggaat attgatggat tagatctaaa    480

caatctgtca gagagggctc gaggggtgtg ttcctactta gctttgtaca gcccagatgt    540

gatatttcta caggaagtta ttcccccata ttatagctac ctaaagaaga gatcaagtaa    600

ttatgagatt attacaggtc atgaagaagg atatttcaca gctataatgt tgaagaaatc    660

aagagtgaaa ttaaaaagcc aagagattat tccttttcca agtaccaaaa tgatgagaaa    720

ccttttatgt gtgcatgtga acgtgtcagg aaatgagctt tgccttatga catcccattt    780

ggagagcacc agagggcatg ctgcggaacg aatgaatcag ttaaaaatgg ttttaaagaa    840

aatgcaagan gctccagagt cagctacagt tatatttgca ggagatacaa atctaaggga    900

tcgagaggtt accanatgtg gtggtttacc caacaacatt gtggatgtct gggagttttt    960

gggcaaacct aaacatngcc agtatacatg ggatacncaa atgaactcta tctnggaaaa   1020

ctgctgcttg taacttcntt ttgatcgaat attttncaaa caccnccaaa nanggaccct   1080

tnttncccna anttggacnt ctnggataaa aaaactggac gggggaaatt tccaangnat   1140

cccnggggcc tccgggccac ttaaaaaaaa attgnaaaa                          1179


<210>  105
<211>  966
<212>  DNA
<213>  Homo sapiens

<400>  105
catcaccatc accatcacgg atcctattta ggtgacacta tagaatcgtc gacccacgcg     60

tccgaggaac ttttacaaag ccagctgact gaaaaggact ctatgattga aaatatgaaa    120

tcttcccaaa catctggcac aaatgaacag tcttcagcaa tagtttcagc tagagattct    180

gaacaagttg cagaattaaa acaggaactg gcaactttaa agtctcagtt aaactcacaa    240

tctgtggaga tcaccaaact acagacagaa aagcaggaac tgttacagaa aacagaagcg    300

tttgcaaaat cagttgaggt acaaggagag accgagacta taatagccac caaaactact    360

gatgtagaag gaagactgtc agcattatta caagagacca aagagttaaa gaatgaaatt    420

aaagctctgt ctgaggaaag aactgccatt aaagagcagc tggattcatc taatagtacc    480

attgccattt tacaaactga gaaagacaaa ctagagttgg aaattacaga ttctaaaaaa    540

gaacaagatg atctcttggt gctcttggcc gatcaagatc agaaaatact gtcattgaag    600

aataaactca aggatcttgg tcatccagtt gaagaagagg atgaacttga atctggagac    660

caagaggatg aggatgatga aagtgaagat cctggcaagg atctagatca tatctagttt    720

tcaaatctct aggaacaata gagattatat cataactctg aagatggact ctaaactttg    780

gtttacctcc atggaaaata aagatttaga aaccaggtgg aaaacattca ctattaagac    840

tattgatata tttttgtaat gttgccaccc atgttgaaaa ccttaaaact gaatttatgt    900

agaacacaca tcttttattt aaatccatct gaactgtccc aaaatgtaat ttgcaaagag    960

cttcaa                                                               966


<210>  106
<211>  849
<212>  DNA
<213>  Homo sapiens

<400>  106
tgagaggatc gcatcaccat caccatcacg gatcctattt aggtgacact atagaatcgt     60

cgacccacgc gtccggcgag agagacccca ttcagccacc tgagctccag ctggtgaccc    120

ctatggctga gggggacaca gggcttcccc gggtgtgggc agcccctgac cggggtcctg    180

tgcccagcac cagtggaatt tcttctgaga tgctggccag tgggcccatt gaggttggct    240

ccttgccagc tggcgagagg gtgtcccgac ccgaagctgc tgtgcctggg taccagcatc    300

caagtgaagc tatgaatgcc cacacacccc agttcttcat ctataaaatt gattcatcca    360

accgagagca gcggctagag gacaaaggag acaccccact ggagctgggt gacgactgta    420

gcctggctct cgtctggcgg aacaatgagc gcttgcagga gtttgtgttg gtagcctcca    480

aggagctgga atgtgctgag gatccaggct ctgccggtga ggctgcccgg gccggccact    540

tcaccctgga ccagtgcctc aacctcttca cacggcctga ggtgctggca cccgaggagg    600

cctggtactg cccacagtgc aaacagcacc gtgaggcctc caagcagctg ttgctatggc    660

gcctgccaaa tgttctcatc gtgcagctca agcgcttctc ctttcgtagt tttatctggc    720

gtgacaagat caatgacttg gtggagttcc ctgttaggaa cctggacctg agcaagttct    780

gcattggtca gaaagaggag cagctgccca gctacgatct atatgctgtc atcaaccact    840

atggaggca                                                            849


<210>  107
<211>  971
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  n is a, c, g, or t

<400>  107
antnagaggn aaattactat gagaggatcg catcaccatc accattcacg gatcctattt     60

aggtgacact atagaatcgt cgacccacgc gtccgcacag ttcctaatac aagaggagtt    120

taataaagaa actgggcagc cccttgttgg tatagaaaca ttaccaccgg atttgagaga    180

ttttgttgag gaagacaacc aacgatttga aaaagaacta gaagaatggg atgcacaact    240

tgcccagaaa gctttgcagg aaaagctttt agcgtctcag aaattgagag agtcagagac    300

ttctgtgaca acagcacaag cagcaggaga cccagaatat ctagagcagc catcaagaag    360

tgatttctca aagcacttga aagaagaaac tattcaaata attaccaagg catcacatga    420

gcatgaagat aaaagtcctg aaacagtttt gcagtcggca attaagttgg aatatgcaag    480

gttggttaag ttggcccaag aagacacccc accagaaacc gattatcgtt tacatcatgt    540

agtggtctac tttatccaga accaggcacc aaagaaaatt attgagaaaa cattactaga    600

acaatttgga gatagaaatt tgagttttga tgaaaggtgt cacaacataa tgaaagttgc    660

tcaagccaaa ctggaaatga taaaacctga agaagtaaac ttggaggaat atgaggagtg    720

gcatcaggat tataggaaat tcagggaaac aactatgtat ctcataattg ggctagaaaa    780

ttttcaaaga gaaagttata tagattcctt gctgttcctc atctgtgctt atcagaataa    840

caaagaactc ttgtctaaag gcttatacag aggacatgat gaagaattga tatcacatta    900

tagaagagaa tgtttgctaa aattaaatga gcaagccgca gaactcttcg aatctggaga    960

ggatcgagaa g                                                         971


<210>  108
<211>  860
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (730)..(730)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (747)..(747)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (751)..(751)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (754)..(754)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (758)..(758)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (761)..(761)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (764)..(764)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (778)..(778)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (783)..(783)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (787)..(787)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (794)..(794)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (802)..(802)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (805)..(805)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (835)..(835)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (837)..(837)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (845)..(845)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (848)..(850)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (859)..(859)
<223>  n is a, c, g, or t

<400>  108
tagagaaatt actatggaga ggatcgcatc accattcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gcccacgcgt ccgagcaccg ccccctggac    120

gagcgggccc tgcaggagaa gctgaagtac tttcccgtgt gcgtgagcac caagccggag    180

cccgaggacg atgcagaaga gggacttggg ggtcttccca gcaacatcag ctctgtcagc    240

tccttgctgc tcttcaacac cactgagaac ctgtacaaga agtatgtctt cctggacccc    300

ctggctggtg ctgtaacaaa gacccatgtg atgctggggg cagagacaga ggagaagctg    360

tttgatgccc ccttgtccat cagcaagaga gagcagctgg aacagcaggt cccagagaac    420

tacttctatg tgccagacct gggccaggtg cctgagattg atgttccgtc ctacctgcct    480

gacctgcccg gcattgccaa cgacctcatg tacagtgccg acctgggccc cggcattgcc    540

ccctctgccc ctggcaccat tccggaactg cccaccttcc acactgaggt agccgagcca    600

ctcaaggcag acctacaaga tggggtacta acagcaccac caccaccccc accgccccca    660

ccacctcccc cagctcctga ggtgctggcc agtgcatccc cactcccacc ctcaaccgcg    720

gcccctgtan gccaaggcgc caggcangac nacngcanca ncancgcgtc tccttcantc    780

cangganctc ccanggaagt gntcnacccc tccggtggcc gggccactct gctanantcc    840

atccnccnnn ctggggggna                                                860


<210>  109
<211>  1333
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (910)..(910)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (938)..(938)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (941)..(941)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (947)..(947)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (962)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (998)..(998)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1004)..(1004)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1024)..(1024)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1045)..(1045)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1056)..(1056)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1060)..(1060)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1081)..(1081)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1122)..(1122)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1125)..(1125)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1134)..(1134)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1146)..(1146)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1156)..(1156)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1161)..(1161)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1163)..(1163)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1170)..(1170)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1180)..(1180)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1183)..(1183)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1193)..(1193)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1203)..(1203)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1206)..(1206)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1219)..(1219)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1221)..(1222)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1228)..(1228)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1232)..(1233)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1239)..(1239)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1249)..(1249)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1254)..(1255)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1260)..(1260)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1262)..(1262)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1267)..(1267)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1271)..(1271)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1278)..(1278)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1286)..(1287)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1294)..(1294)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1299)..(1299)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1302)..(1302)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1304)..(1304)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1313)..(1313)
<223>  n is a, c, g, or t

<400>  109
nntagagaga ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gcccacgcgt ccgctctgcc agcaggttgg    120

gagatggcaa agacatcttc tggtcagaga tacttcttaa atcacatcga tcagacaaca    180

acatggcagg accccaggaa ggccatgctg tcccagatga acgtcacagc ccccaccagt    240

ccaccagtgc agcagaatat gatgaactcg gcttcaggtc ctcttcctga tggatgggaa    300

caagccatga ctcaggatgg agaaatttac tatataaacc ataagaacaa gaccacctct    360

tggctagacc caaggcttga ccctcgtttt ggtaaagcca tgaaccagag aatcagtcag    420

agtgctccag tgaaacagcc accacccctg gctccccaga gcccacaggg aggcgtcatg    480

ggtggcagca actccaacca gcagcaacag atgcgactgc agcaactgca gatggagaag    540

gagaggctgc ggctgaaaca gcaagaactg cttcggcagg caatgcggaa tatcaatccc    600

agcacagcaa attctccaaa atgtcaggag ttagccctgc gtagccagtt accaacactg    660

gagcaggatg gtgggactca aaatccagtg tcttctcccg ggatgtctca ggaattgaga    720

acaatgacga ccaatagctc agatcctttc cttaacagtg gcacctatca ctctcgagat    780

gagagtacag acagtggact aagcatgagc agctacagtg tccctcgaac cccaaatgac    840

tttcctgaac agtgtgggat gagatggata caggtgatac tatcaaccaa agcaccctgg    900

ccctcaaagn caaaaccgtt ttcccaaaac tacctttnaa nccattncct gggaaaaatg    960

tnggaccttt ggaaaccctg ggaagggnaa tggaatgnac nttnaaaggg aaagggagct   1020

tgantgccca agttntggca agaanccttt gaattntgan ttccttaatg acttggaatt   1080

ntgtttttgg ctgccnccaa cctaaaaaaa aaaaaagctt tnttnaattg gttntaaaaa   1140

cccccngggg aaattnaatt ntnaattctn ggaaggattn tanggaaaaa ttngccccga   1200

aanttnctta aaccagttng nntttttngg gnnaaaacna aaaaaaatna aaannccccn   1260

cnaaaanttt nacccccntt tggccnnttt gtcnatggng gntnaagatt ggngaccctt   1320

tcccaggggc ctc                                                      1333


<210>  110
<211>  833
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (674)..(674)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (696)..(696)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (772)..(772)
<223>  n is a, c, g, or t

<400>  110
tatagagaat tactatgaga ggtcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgactc tggaccttgg ctgtcactca gttgaagaac aagcacagat    120

tgatgctgaa atggactcta ctcctgttgg ctatcagtac ggtcaaggat ctgatgtcac    180

atccaaaagc tttccagatg atctgcctcg gatgcgattc aagtgcccgt actgcacaca    240

tgtggtgaag cggaaggcag acctaaagcg ccaccttcgt tgtcatacag gagaaaggcc    300

ctatccatgt caagcttgtg gaaaaagatt tagcaggcta gaccatctaa gtagccattt    360

tcgaacaatt caccaggcat gtaaactcat ctgcagaaaa tgtaaacgtc atgtgacaga    420

tctaacaggg caagtggtac aggagggaac caggcgctac agactgtgta atgagtgtct    480

tgcagaattt ggcatagaca gcctccccat tgacttggaa gctgaacaac atcttatgtc    540

cccatcagat ggagataagg attccagatg gcacttgagt gaagatgaga atagatccta    600

tgtggagatt gtagaagatg ggtctgctga tctggtcatc caacaggttg atgatagtga    660

agaagaagaa gaanaagaaa ttaagcccaa cattangtag ctgtaatgtg aaccaacaga    720

gctggcatgt ctgcaattta cattgacttc ctgtatctct cccttctatg gncggagtct    780

agttaacaat ttatcacact gactttaaag aatgatctga tataactgca tgc           833


<210>  111
<211>  1322
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (835)..(835)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (866)..(866)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (947)..(947)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (952)..(952)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (954)..(954)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (959)..(959)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (963)..(963)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (965)..(965)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1016)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1018)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1028)..(1028)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1041)..(1041)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1092)..(1092)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1112)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1114)..(1114)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1127)..(1128)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1130)..(1130)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1150)..(1150)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1168)..(1168)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1178)..(1178)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1184)..(1184)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1193)..(1193)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1198)..(1198)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1201)..(1201)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1213)..(1213)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1221)..(1222)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1224)..(1224)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1249)..(1249)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1253)..(1255)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1265)..(1265)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1267)..(1267)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1269)..(1269)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1271)..(1271)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1273)..(1274)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1289)..(1289)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1295)..(1295)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1297)..(1297)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1299)..(1299)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1317)..(1317)
<223>  n is a, c, g, or t

<400>  111
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc ccacgcgtcc gtggtgctgg aacagttcct    120

gagcgcgctg cccgccgaca cgcaggcctg ggtgtgcagc cggcagccgc agagcgggga    180

ggaggcggtg gccctgctgg aggagctctg ggggccagca gcctcccccg atgggtcgtc    240

agcaacgagg gtgcctcagg atgtgacgca gggccctggg gccacaggtg gaaaggagga    300

cagtgggatg attcccttag gcaccgcccc tggggctgag gggccggcgc ctggggactc    360

ccaggctgtg cgcccctaca agcaggagcc cagcagcccc ccgctggcgc ctggcctgcc    420

cgccttccta gcggccccgg gcaccacgtc ctgccccgag tgcggcaaaa cgtccctgaa    480

accagctcac ctgctgcgcc accggcagag ccactcgggc gagaagccgc acgcctgccc    540

tgagtgcggg aaggcctttc ggcgcaagga gcacctgcgg cgccaccgcg acacgcaccc    600

cggcagcccc ggcagccccg ggcccgcgct gcgccctctg cccgcccgtg agaagcccca    660

cgcgtgctgc gagtgtggca agaccttcta ctggcgcgag cacctggtgc gccaccgcaa    720

gacgcactcg ggagcgcggc cctttgcctg ctgggagtgt ggcaagggct tcgggcgccg    780

cgagcacgtg ctgcgccacc agcgcatcca cggccgggca gcggccagcg cgcanggggc    840

ggtagctccg ggcccggatg gtggangccc ctttccgccc tggccttggg ttagccgcct    900

cccggccagc gccatctccg cccttggtgc tgcccccggg cggtacntgc tntntccanc    960

gcnanttggc ctcttcctct cttctttcct ccaatcgtct tcttcaactt gggctncntt   1020

gtttgaantt ccaangcctt nctattcttt tcaattcttt ttccccaaan tttaattttt   1080

tttttaaggt tnacttaacc cccccttttc cntnattttc ggctttnncn tggtgaaagg   1140

gcctctcccn aaggttcctc tttccccntt tttttttntg gggncaacct ccnttccncc   1200

natttttttt ccngcctttt nncnaaaaaa aaataaaatt ggaacttang gannnaaaaa   1260

atttngncna ncnncccttt taaaaaaana aaaangntng ttttccaaaa tttcccnaaa   1320

tg                                                                  1322


<210>  112
<211>  1346
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1257)..(1257)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1287)..(1287)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1310)..(1310)
<223>  n is a, c, g, or t

<400>  112
tactgactta cctataaata ggcgtatccg aggccctttc gtcttcacct cgagaaatca     60

taaaaaattt atttgctttg tgagcggata acaattataa tagattcaat tgtgagcgga    120

taacaatttc acacagaatt cattaaagag gagaaattaa ctatgagagg atcgcatcac    180

catcaccatc acggtcgacc cacgcgtccg gagacagctg agaagtgcag ccagtccaac    240

aaccagttcc agaagatctc agaggaactc aaagtgaaag gtcccaagga ctccaaggac    300

agccacacgt ctgtcaccat ggaagctctg ctctacaagc ccattgaccg ggtcactcgg    360

agcaccctag tcctacacga cctgctgaag cacacacctg tggaccaccc cgactacccg    420

ctgctgcagg atgccctccg catctcccag aacttcctgt ccagcatcaa cgaggacatc    480

gacccccgcc ggactgcagt gacaacgccc aagggggaga cgcgacagct ggtgaaggac    540

ggcttcctgg tggaagtgtc agagagctcc cggaagctgc ggcacgtctt cctctttaca    600

gatgtcctac tgtgtgccaa gctgaagaag acctctgcag ggaagcacca gcagtatgac    660

tgtaagtggt acatccccct ggccgacctg gtgtttccat cccccgagga atctgaggcc    720

agcccccagg tgcacccctt cccagaccat gagctggagg acatgaagat gaagatctct    780

ggccctcaga gtgaaatcca gaaggagaaa gccaacaaag gccagagccg ggccatcgag    840

cgcctggaaa aaaaaagttt tgagaatgag ttcctgctgc tgctcacctc ccccacggcc    900

gcaaatcgca tgcgagctca attagctgaa cctggaaccc tgttgataaa tccagaatga    960

acctcaaaac tccatccgga attggtcaaa acccctcgtt gccccccggg gctttttatt   1020

tgggagaaac cacgccaccc ttgccaaatt tttcgggcac ctgggaagcc aaaacggaaa   1080

aaaaaaccct ggaataacac ccgtggaaat taccccaggg actgaaagaa aaccttttcg   1140

gggcttcgcc catgatgcct cccggccact ataaaaatcg cccctgcata ttaggccttt   1200

cttaaacacc tcacaaaaga accgcacact tgccaggccg tagtcctctt gcgaccnagc   1260

ggatatgccc actaaatacc aacgctncaa aactcgacgc caccaaggan aaacaactat   1320

ccccaacgac ccacgacaca tcagac                                        1346


<210>  113
<211>  915
<212>  DNA
<213>  Homo sapiens

<400>  113
ctatgagagg tcgcatcacc atcaccatca cggatcctat ttaggtgaca ctatagaatc     60

gtcgacccac gcgtccgctc tctcgtccgg tgtctgcgtg ccaagctgta ttaccaactg    120

cttgtggact aaagaggatg gacatagaac ttccacctct gctgtcccta acctgtttgt    180

tccattgaac actaacccaa aagaggtcca ggagatgagg aacaagatcc gagagcagaa    240

tttacaggac attaagacgg ctggccctca gtcccaggtt ttgtgtggtg tagtgatgga    300

caggagcctc gtccagggag agctggtgac ggcctccaag gccatcattg aaaaggagta    360

ccagccccac gtcattgtga gcaccacggg ccccaacccc ttcaccacac tcacagaccg    420

tgagctggag gagtaccgca gggaggtgga gaggaagcag aagggctctg aagagaatct    480

ggacgaggct agagaacaga aagaaaagag tcctccagac cagcctgcgg tcccccaccc    540

gcctcccagc actcccatca agctggagga aggagacgga tgcgctagag agtacctgtt    600

accctaacct tgtgccggag ccgactactg gagatgacag tgatgctgcc acctttaagc    660

caactctccc cgatctgtcc cctgatgaac cttcagaagc actcggcttc ccaatgttag    720

agaaggagga ggaagcccat agacccccaa gccccactga ggcccctact gaggccagcc    780

ccgagccagc cccagaccca gccccggtgg ctgaagaggc tgccccctca gctgtcgagg    840

agggggccgc cgcggaccct ggcagcgatg ggtctccagg caagtccccg tccaaaaaga    900

agaagaagtt ccgta                                                     915


<210>  114
<211>  839
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (769)..(769)
<223>  n is a, c, g, or t

<400>  114
gagagatact atgagaggtc gcatcccatc accatcacgg atcctattta ggtgacacta     60

tagaatcgtc gactctggac cttggctgtc actcagttgg agcgcggccc ctgggttcga    120

acacggcacc cgcactgcgc gtcatggtgc aggcctggta tatggacgac gccccgggcg    180

acccgcggca accccaccgc cccgaccccg gccgcccagt gggcctggag cagctgcggc    240

ggctcggggt gctctactgg aagctggatg ctgacaaata tgagaatgat ccagaattag    300

aaaagatccg aagagagagg aactactcct ggatggacat cataaccata tgcaaagata    360

aactaccaaa ttatgaagaa aagattaaga tgttctacga ggagcatttg cacttggacg    420

atgagatccg ctacatcctg gatggcagtg ggtacttcga tgtgagggac aaggaggacc    480

agtggatccg gatcttcatg gagaagggag acatggtgac gctccccgcg gggatctatc    540

accgcttcac ggtggacgag aagaactaca cgaaggccat gcggctgttt gtgggagaac    600

cggtgtggac agcgtacaac cggcccgctg accattttga agcccgcggg cagtacgtga    660

aatttctggc acagaccgcc tagcagtgct gcctgggaac taacacgtgc ctcgtaaagg    720

tcccccatgg tatgactgag cagaaaatca tactttctct tgcttttana gatagccttg    780

agctagttat ctttcttttg tagatattga tcagatattt gtatgaagga tctagaagc     839


<210>  115
<211>  857
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<400>  115
ngatagagag atactatgag aggatgcatc ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgactc tggaccttgg ctgtcactca gttaaaaatg gagtgaagca    120

aataccattt ccatctggta ctccactgca cgctaattca atggtttctg acaatgtgat    180

acagtctaca gcactaacaa acgtatcttc tgctacgaca cacttcataa aatgacgaac    240

tggagacgac aacaaagcca aagataaaat tgaaaataaa ggagataaca atgagagaga    300

acacccatca atagctggaa gtgcctactc taagccaata gatgtttccc gtctggatct    360

tcgaagtgga tgcatcataa ctgctagaat acaccctgat gcatattctt tgtatgtgga    420

aagaatatat gtcgtgacaa ctaccacaat gacagttgtc actggcctgg tgacatctgg    480

tcctcttgaa catatgccaa atcggatggt gattttacat tgtaacctga aacctgccaa    540

gatgagggga ctattatctc acgcaatgtc aagtgtgcta gttccccaga aaaattgaaa    600

tcctggctcc tcccaatggg tctgttcctg gacacagaat tacttttgat gctttgccac    660

gagagcctga caaggagctg aatcctagca tgaccattgt gaagcgatcc gcctgatcct    720

cacactatga tgactgtgtg gctacatcaa agcattccct ttgaggtgaa aggaaaggat    780

tagtaggctc caacctgatc aacgtggatc aataaaagct ccgctaacag agaaattcag    840

acaactttaa ggataag                                                   857


<210>  116
<211>  912
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (346)..(346)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (366)..(366)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (455)..(455)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (484)..(484)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (490)..(490)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (495)..(495)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (504)..(504)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (537)..(537)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (637)..(637)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (666)..(666)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (678)..(678)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (698)..(698)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (721)..(721)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (730)..(730)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (740)..(740)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (748)..(748)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (755)..(755)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (781)..(781)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (790)..(790)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (792)..(792)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (794)..(794)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (799)..(799)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (803)..(803)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (821)..(822)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (846)..(846)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (848)..(848)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (855)..(855)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (858)..(858)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (862)..(863)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (868)..(868)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (872)..(872)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (878)..(879)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (881)..(881)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (890)..(890)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (899)..(899)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (905)..(905)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (907)..(907)
<223>  n is a, c, g, or t

<400>  116
antagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gcccacgcgt ccggaaagtc ccactcgccc    120

tcggcttctc cctgcccggc cgccggtgtc ccgcccgccg cctccccgcg cagcccggcc    180

cgacccgcgg cgatggccca gcccggggac ccgcggcgcc tctgcaggct ggtgcaggag    240

ggccggctgc gcgccctgaa ggaggagctg caggcggccg ggggctgccc ggggccggcc    300

ggggataccc tcctgcactg cgccgcgcgc cacgggcatc gggacntgct ggcctatctg    360

gccgangcct ggggcatgga catcgaggtc accaaccgag actacaagcg gcctctgcac    420

gaggcggcct ccatgggcca ccgagactgc gtgcnctacc tgctgggccg gggggcagcg    480

gtcnactgcn tgaanaaggc cgantggact cctctgatga tggcctgcac aaggaanaac    540

ctgggggtga tccaggagct ggtggaacat ggcgccaatc cactcctgaa gaacaaagat    600

ggctggaaca gtttccacat tgccagtcga gaaggcnacc ctctgatcct ccaagtacct    660

gctcantgtt tgcccagngt gccctggaat acagaganca aaattagaag gactcctctg    720

natactgcan caatgcatgn accatttnga ggcantcaaa gtgcttcttt aagaggtgcc    780

natatgaacn anantacana aanaattgtt ggcgtcaccg nnttgatgga actcaattca    840

attttntnca catcnaantc tnntaagnct gntccttnna ntaaaaatgn ggctttgcnt    900

ttcananaaa aa                                                        912


<210>  117
<211>  492
<212>  DNA
<213>  Homo sapiens

<400>  117
gatagagaga tactatgaga ggtcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgactc tggaccttgg ctgtcactca gttggaggag atgggcagcc    120

ggacccgcga ccgcctggac gaggtgaagg agcaggtggc ggaggtgcgc gccaagctgg    180

aggagcaggc ccagcagata cgcctgcagg ccgaggcctt ccaggcccgc ctcaagagct    240

ggttcgagcc cctggtggaa gacatgcagc gccagtgggc cgggctggtg gagaaggtgc    300

aggctgccgt gggcaccagc gccgcccctg tgcccagcga caatcactga acgccgaagc    360

ctgcagccat gcgaccccac gccaccccgt gcctcctgcc tccgcgcagc ctgcagcggg    420

agaccctgtc cccgccccag ccgtcctcct ggggtggacc ctagtttaat aaagattcac    480

caagtttcac gc                                                        492


<210>  118
<211>  1393
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (868)..(868)
<223>  n is a, c, g, or t

<400>  118
nccgcactcc ccctaaggaa tactagagag gacgcatccc atcacatcac ggtcgaccca     60

cgcgtccggg ccagcaggtg tctctggctg aaggggatag gttcctactg cttcgaaaga    120

ccaactccga ctggtggttg gcaagacgcc tagaagctcc ctccacctct cgacccatct    180

tcgtcccagc agcctatatg atagaggaat ccatcccttc ccagagtcca actaccgtca    240

tccccggcca attgctctgg actcctgggc cgaagttgtt tcatggttcc ctggaggagt    300

tgtctcaggc cctcccaagc agggctcagg ctagctcgga gcagcctcct ccacttcccc    360

gcaaaatgtg taggagcgtc agcactgaca atctgagccc cagccttctg aagcctttcc    420

aggaaggacc aagcggaaga tccctctccc aggaagactt gccgtcagaa gccagtgcca    480

gcacagcagg cccccagccc ctcatgtcag agccccctgt gtactgtaac ctggtggacc    540

ttcgccgctg tcctcggtcc ccacccccag gccctgcatg ccccctgctg cagaggctgg    600

atgcctggga gcagcacctg gaccccaact ctggacgctg cttctacata aattcactga    660

ctggctgcaa gtcctggaag ccccggcgcc gcagtcgcag cgagacgaac cctggctcca    720

tggaggggac acagaccctg aagaggaaca atgatgtcct gcaacctcag gcaaagggct    780

tcagatctga cacagggacc ccagaaccgc ttgacccaca gggttcactc agcctcagcc    840

aacgcacctc gcagcttgac cctccagnct tgcaggcccc tcgacctctg ccgcagcttc    900

tggacgaccc ccatgaggtg gaaaaagccg gtctgctccc atgaccaaaa tggccaaggg    960

gggcgcaagc tcaagaaaaa agggggtccc tcttgggggg cgataaaagc acaccaccgg   1020

cgctctacca aaagccccaa cccacacccg cccacctccg atgggaacac cgttcccgcc   1080

cccaacaaac ctgacacttc tccgctcaca cgacacacgt cgaccactca cccacgcaat   1140

atccctctcc atcaacacta catgattctc tacaccaccc atcccaccca cacatatatg   1200

ctctccacaa catcgaaatc ttaagtccga ctacacttac cccaaccgaa catcgcacac   1260

accagaccca gatcacccac ataataacca acacaaccac cgtacaacaa tctactctat   1320

ataacaccta aacagcttaa actatcataa tatcatgcac cgactagtac acaaaaatct   1380

cgaatataac cat                                                      1393


<210>  119
<211>  879
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (687)..(687)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (741)..(741)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (744)..(744)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (761)..(761)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (773)..(773)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (817)..(817)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (821)..(821)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (841)..(843)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (877)..(877)
<223>  n is a, c, g, or t

<400>  119
gagatactat gagaggtcgc atcccatcac catcacggat cctatttagg tgacactata     60

gaatcgtcga ctctggacct tggctgtcac tcagttagtg aggtggctga ggagagggag    120

cggctgggcc agcaggcagc caggcagcgg gcggagctgg aagagctgag gcagcagctg    180

gaggagagca gctctgcact gacccgagcc ctgagggctg agtttgagaa gggcagggag    240

gagcaggagc gccggcacca gatggagctg aataccctga agcagcagct ggagctggag    300

aggcaggcgt gggaggccgg ccgcaccagg aaggaggagg cgtggctgct gaaccgggaa    360

caggagctga gggaagaaat ccggaaaggc cgggacaagg agattgagct ggtcattcac    420

cggctggagg ccgacatggc gctggccaag gaggagagtg agaaggctac cgagagccgc    480

atcaagcgct tacgggacaa gtacgaggcc gagctctccg agctggagca gtcggagcgg    540

aagcttcagg agcggtgctc ggagctgaag ggccagcttg gggaggccga gggcgagaat    600

ctgcgtctgc agggccttgt gcggcagaag gagcgggcgc tggaggatgc gcaggcggtg    660

aacgagcagc tttctagcga gcgcagncac ctggcccagg tgatccgccc aggagtcgag    720

gaccggctgg cagcctctga nggnagagac gcgcaggcca nggccgagct ggncacgctg    780

caggcccgca gcagctggag ctgggagagt gcaccgnagg ntgagacagc ctcgcgagaa    840

nnngagagcg tgagcagctc cggaccacat gagctgngt                           879


<210>  120
<211>  869
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (720)..(720)
<223>  n is a, c, g, or t

<400>  120
agagagatac tatgagaggt cgcatcacca tcaccatcac ggatcctatt taggtgacac     60

tatagaatcg tcgactctgg accttggctg tcactcagtt atgatgaaga agcagaaagt    120

gaagaccatc ttcccgcaca ctgcgggctc caacaagacc ttactcagct ttgcacaggg    180

agatgtcatc acgctgctca tccccgagga gaaggatggc tggctctatg gagaacacga    240

cgtgtccaag gcgaggggct ggttcccgtc gtcgtacacg aagttgctgg aagaaaatga    300

gacagaagca gtgaccgtgc ccacgccaag ccccacacca gtgagaagca tcagcaccgt    360

gaacttgtct gagaatagca gtgttgtcat ccccccaccc gactacttgg aatgcttatc    420

catgggggca gctgccgaca ggagagcaga ttcggccagg acgacatcca cctttaaggc    480

cccagcgtcc aagcccgaga ccgcggctcc taacgatgcc aacgggactg caaagccgcc    540

ttttctcagc ggagaaaacc cctttgccac tgtgaaactc cgcccgactg tgacgaatga    600

tcgctcggca cccatcattc gatgagagga cagccaagga ctctcccggg cctctccggt    660

tctcccttgc ggaatgatgg gcgcatcctg tctgcacgtg ctgacggtcg ggaagctcan    720

tggagaggct actctaatgt cgctgctaag caatcaggct cctgtccagg aatttgggtg    780

acagttctgc cttagataat gataatatct atgacactca ccttaaatat tcttctatct    840

gtcagaaaga aactggttta tcttaaaaa                                      869


<210>  121
<211>  1146
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (863)..(863)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (887)..(887)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (917)..(917)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (983)..(983)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (993)..(993)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1025)..(1025)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1036)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1042)..(1042)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1055)..(1055)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1060)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1065)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1076)..(1076)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1089)..(1090)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1093)..(1093)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1120)..(1120)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1125)..(1125)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1132)..(1132)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1144)..(1144)
<223>  n is a, c, g, or t

<400>  121
aggaaantta nctatgaaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg gtttagttat ggcagagaac gatgtggaca    120

atgagctctt ggactatgaa gatgatgagg tggagacagc agctggggga gatggggctg    180

aggcccctgc caagaaggat gtcaagggct cctatgtctc catccacagc tctggctttc    240

gtgacttcct gctcaagcca gagttgctcc gggccattgt cgactgtggc tttgagcatc    300

cgtcagaagt ccagcatgag tgcatccctc aggccattct gggaatggat gtcctgtgcc    360

aggccaagtc gggcatggga aagacagcag tgtttgtctt ggccacactg caacagctgg    420

agccagttac tgggcaggtg tctgtgctgg tgatgtgtca cactcgggag ttggcttttc    480

agatcagcaa ggaatatgag cgcttctcta aatacatgcc caatgtcaag gttgctgttt    540

tttttggtgg tctgtctatc aagaaggatg aagaggtgct gaagaagaac tgcccgcata    600

tcgtcgtggg gactccaggc cgtatcctag ccctggctcg aaataagagc ctcaacctca    660

aacacattaa acactttatt ttggatgaat gtgataagat gcttgaacag ctcgacatgc    720

gtcgggatgt ccaggaaatt tttcgcatga ccccccacga gaagcaggtc atgatgttca    780

gtgctacctt gagcaaagag atccgtccag tctgccgcaa gttcatgcaa gatccaatgg    840

agatcttcgt ggatgatgag acnaagttga cgctgcatgg gttgcancag tactacgtga    900

aactgaagga caacganaag aaccggaagc tctttgacct tctggatgtc cttganttca    960

accaggtggt gatctttgtg aantctgggc acnggtgcat ngccttggcc cacctactan   1020

tggancaaaa ctcccngcca tngccatccc ccggnggann ccccnagaan aaaagncttt   1080

tcccggaann acnatttnaa nattttcaca aaaattttgn ggctncaacc tnttggccaa   1140

gctnga                                                              1146


<210>  122
<211>  1190
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (979)..(979)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (990)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (995)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1014)..(1014)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1023)..(1023)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1077)..(1077)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1089)..(1089)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1120)..(1120)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1123)..(1123)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1127)..(1127)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1129)..(1129)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1139)..(1139)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1152)..(1152)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1155)..(1155)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1160)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1164)..(1164)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1169)..(1169)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1173)..(1173)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1177)..(1177)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1179)..(1179)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1182)..(1182)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1186)..(1186)
<223>  n is a, c, g, or t

<400>  122
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc caagctcccc aaaaaggcca caaagacagc    120

cccacctgcc ctgcctacag gttatgattc agaggaggag gaagagagca ggcccatgag    180

ttacgatgag aagcggcagc tgagcctgga catcaacaaa ttacctgggg agaagctggg    240

ccgagttgtg catataatcc aagccaggga gccctcttta cgtgattcaa acccagaaga    300

gattgagatt gattttgaaa cactcaagcc atccacactt agagagcttg agcgctatgt    360

cctttcctgc ctacgtaaga aaccccggaa gccctacacc attaagaagc ctgtgggaaa    420

gacaaaggag gaactggctt tggagaaaaa gcgggaatta gaaaagcggt tacaagatgt    480

cagcggacag ctcaattcta ctaaaaagcc ccccaagaaa gcgaatgaga aaacagagtc    540

atcctctgca cagcaagtag cagtgtcacg ccttagcgct tccagctcca gctcagattc    600

cagctcctcc tcttcctcgt cgtcgtcttc agacaccagt gattcagact caggctaagg    660

ggtcaggcca gatggggcag gaaggctccg caggaccgga cccctagacc accctgcccc    720

acctgcccct tccccctttg ctgtgacact tcttcatctc acccccccct gcccccctct    780

aggagagctg gctctgcagt gggggaggga tgcagggaca tttactgaag gagggacatg    840

gacaaaacaa cattgaattc ccagccccat tggggagtga tctcttggac acagagcccc    900

cattcaaatg gggcagggca agggtgggag tgtgcaaagc cctgatctgg agttacctga    960

ggccatagct gcccctatnc cttctanggn cctgntttga natggttgtt ctanttattt   1020

tanctaggta agctggggga aggtggggcc ctggtccctc acctcctggg gaggganaag   1080

gggagctcnt tttttacntg attttttttt cacccggttn ccntttncnt ccccccttng   1140

ggcccggggg tncanccttn cccnttggnc ccnggangnt tnttgntcca              1190


<210>  123
<211>  856
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (836)..(837)
<223>  n is a, c, g, or t

<400>  123
cccgaacaat aagaaatact agagaggatg catcccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg actctggacc ttggctgtca ctcagttata gaggagacgg    120

attcagaagg gctacagacc aaggttgttg aaaaccagac atatgatgag cgtctagaga    180

ttaacgactc cgaagaggtt gcaagtattt atactccaac cccaagacac caaggacttc    240

ctcgttctgc ccatcttcct aacaaggcta tggctgataa cagcagtgat gagtgtgaag    300

aggaaaataa caaggagaag aagaagacct cacagttgac acctcaacgg ggctttagtg    360

aaaatgagga tgacgatgat gatgatgatg attcatctga aactgattct gattctgatg    420

atgatgatga agagcatgga gcccctctgg aaggggccta tgaccctgca gactatgagc    480

atttgccagt ttctgctgaa attaaggaac tcttccagta catcagtagg tacacacctc    540

agttgattga cctggaccac aaactgaagc ctttcattcc tgattttatc ccagctgtcg    600

gggatattga tgcattctta aaggtcccac gtcctgatgg aaagcctgac aaccttggcc    660

tattggtatt ggatgaacct tctacaaagc agtcagaccc tacggtgctc tcactctggt    720

taacagagaa tttctagcag cacaacatca cacaacatat gaaagtaaaa agcctagaag    780

atgcagaaaa gaatcccaag cccatgacac gtggattgag acatctctga atacanncgt    840

ctagcccctg cgatgt                                                    856


<210>  124
<211>  1347
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (644)..(644)
<223>  n is a, c, g, or t

<400>  124
cgtccctgcc ttaggaatac ttgagaggat gcatcacatc acatcacggt cgacccacgc     60

gtccgctcag agcagcgaca gtgaggccgg tgaccctgca agccagagct gacagcccca    120

ctgtgcctga gcccgtgcac cgcccacagg acccatggca cattcccggt gtgcctgagc    180

ccgtgcaccg cccacaggac ccgtggcaca ttcccggtgt gcctgagccc gtgcaccgcc    240

cacaggaccc gtggcacatt cccggtgtgc ctgagcccgt gcaccgccca caggacccgt    300

ggcacattcc cggtgtgcct gagcccgtgc accgcccaca ggacccgtgg ccttggcttc    360

agttggtgcc tccagccgag ttggcctatt gcctgctcat gctgctgctt gcacactgca    420

tgaaacagca ggccagacca ggacatccag actttctcca tcgtgaggcc tgggcctgcc    480

tttctgcagc cggaggtctc gccagccctg gactcctgct ttgggccaca gcaagacctc    540

gggcgagtgg agaggcgggg ccaggccggg cccttgtggg tgctgatgct gcatgttgtc    600

cccgacacag cgtcctctcc ctggtggaca tccccagcgg tcangtgctt ccccaagggc    660

agtgaggggt gaacatccag ggcctacctg gctgtgcacg ctgcagccac actgtggaag    720

ctgcccctcc ccgaggaccc gcctcccttg ctgatgccag gatctcggcg catagaccac    780

tctgccccag cggtcgtaac aaaaaggtct ctctgtttct ccaactcaac ttcaaaataa    840

cctgggaggc caaaaaaagg tcagctcttc tagatcgggc agtgcttaaa accgggagct    900

ccaccgggcg caagggtcat gccataaatc ccacactttt cgaacccaag ggtgaaagat    960

ttctttaagc ccaaatttca aaacaccctt gggaaacaaa aaaaaccctt ttttttaaaa   1020

aaatacccaa agggaaaacc gggaaatttt tcccaaaatt tattcacccc ccccccaacc   1080

ctgaaaaaac tgcagagagg ggttggtttt tccaaaaaaa tttccccccc cccaaaaaga   1140

aaaacccacc cctcttcccc ccagtttttt tgtcttctaa gatccactcc cccccgaggg   1200

gatacaccaa acaccctctc atatcactcc tataaaaaaa cacactcccc caccacccct   1260

cctggacaac acataacttt gaaaaaaaca aacattcctc ccctctgatt ccctaaaccc   1320

cataaaagaa actcctcccc cgttcgc                                       1347


<210>  125
<211>  632
<212>  DNA
<213>  Homo sapiens

<400>  125
agatactatg agaggtcgca tcaccatcac catcacggat cctatttagg tgacactata     60

gaatcgtcga ctctggacct tggctgtcac tcagtttttg gagccttgct gggcactcct    120

gtaggaggcc tgctgatggc atttcagaag tactctggtg agactgttca ggaaagaaaa    180

cagaaggatc gaaaggcact ccatgagcta aaactggaag agtggaaagg cagactacaa    240

gttactgagc acctccctga gaaaattgaa agtagtttac aggaagatga acctgagaat    300

gatgctaaga aaattgaagc actgctaaac cttcctagaa acccttcagt aatagataaa    360

caagacaagg actgaaagtg ctctgaactt gaaactcact ggagagctga agggagctgc    420

catgtccgat gaatgccaac agacaggcca ctctttggtc agcctgctga caaatttaag    480

tgctggtacc tgtggtggca gtggcttgct cttgtctttt tcttttcttt ttaactaaaa    540

atggggctgt tgtactctca ctttacttat ccttaaattt aaatacatac ttatgtttgt    600

attaatctat caatatatgc atacatgaat at                                  632


<210>  126
<211>  968
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (804)..(804)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (942)..(942)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (946)..(968)
<223>  n is a, c, g, or t

<400>  126
naattagaga aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgggaagct gttcggggct ggagggggta    120

aggccggcaa gggcggcccg accccccagg aggccatcca gcggctgcgg gacacggaag    180

agatgttaag caagaaacag gagttcctgg agaagaaaat cgagcaggag ctgacggccg    240

ccaagaagca cggcaccaaa aacaagcgcg cggccctcca ggcactgaag cgtaagaaga    300

ggtatgagaa gcagctggcg cagatcgacg gcacattatc aaccatcgag ttccagcggg    360

aggccctgga gaatgccaac accaacaccg aggtgctcaa gaacatgggc tatgccgcca    420

aggccatgaa ggcggcccat gacaacatgg acatcgataa agttgatgag ttaatgcagg    480

acattgctga ccagcaagaa cttgcagagg agatttcaac agcaatttcg aaacctgtag    540

ggtttggaga agagtttgac gaggatgagc tcatggcgga attagaagaa ctagaacagg    600

aggaactaga caagaatttg ctggaaatca gtggacccga aacagtccct ctaccaaatg    660

ttccctctat agccctacca tcaaaacccg ccaagaagaa agaagaggag gacgacgaca    720

tgaaggaatt ggagaactgg gctggatcca tgtaatgggg tccagcgctg gctgggccca    780

gacagactgt ggtggcctgc gcancgagca ggcgtgtgcg tgtgtggggc aggcaggatg    840

tggtgcaggc aggttccatc gctttcgact ctcactccaa agcagtaggg ccgcgttgct    900

gctcactctc tgcatagcat ggtctgcact ggaaaaattg gncggnnnnn nnnnnnnnnn    960

nnnnnnnn                                                             968


<210>  127
<211>  1000
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (783)..(783)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (800)..(800)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (805)..(805)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (859)..(859)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (908)..(908)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (922)..(922)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (940)..(940)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (945)..(946)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (952)..(952)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (955)..(955)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (960)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (975)..(976)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (992)..(992)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (995)..(996)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1000)..(1000)
<223>  n is a, c, g, or t

<400>  127
aatagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gctccgggga gcagctcctg tggggcagaa    120

cggctacaca cagttggggg acctggctca gcccggcccc gagctttctc ccacagcggg    180

gtacacagcc tggacggcgg agaagtagac agtcaggcgc tacaggaact gacgcagatg    240

gtgtctggcc ctgcatcgta ctctggccca aagccttcta cccagtatgg agctccagga    300

ccctttgcag cccctggtga gggaggtgcc ttggcggcca ctgggcggcc cccgctgctg    360

cccacccgag cttctcgttc tcagcgtgcg gccagtgagg acatgacgag tgatgaggag    420

cgcatggtca tctgtgagga ggaaggggat gatgatgtca ttgctgacga tggcttcggc    480

accactgaca ttgatctcaa gtgcaaggag cgggtgaccg acagcgagag tggggacagc    540

tctggggagg acccagaggg caacaagggc tttggtcgga aggtgttttc acctgtgatc    600

cgttcctcct ttacccactg ccgcccccca ctggaccctg agcccccagg gcccccggat    660

cctcctgtag cctttggcaa aggctatggt tccgccccat cctcctctgc gtcctcgcct    720

gcttcctcct cagcctcggc agccacctcc ttctcactgg gctcaggaac cttcaaggcc    780

cangagtctg gtcagggcan cacancgggc cccctacggc ccccaccccc tggggctggg    840

ggtccagcga caccttccna aggcaacccg gttcctccca atggatcctg ccacctttcc    900

ggcgcaanaa acccaaaagt gngggttggc ctggaaaccn accanncccc tnaantcatn    960

nnggccccct cccannggaa gaagaaactt cntgnnaaan                         1000


<210>  128
<211>  992
<212>  DNA
<213>  Homo sapiens

<400>  128
tgagaggatc gcatcaccat caccatcacg gatcctattt aggtgacact atagaatcgt     60

cgacccacgc gtccgtctac accgaggtcc gcgagctggt gagcctcaag caggagcagc    120

aggctttcaa ggaggcggcc gacacggagc ggctcgccct gcaggccctc acggagaagc    180

ttctcaggtc tgaggagtcc gtctcccgcc tcccggagga gatccggaga ctggaggaag    240

agctccgcca gctgaagtcc gattcccacg ggccgaagga ggacggaggc ttcagacact    300

cggaagcctt tgaggcactc cagcaaaaga gtcagggact ggactccagg ctccagcacg    360

tggaggatgg ggtgctctcc atgcaggtgg cttctgcgcg ccagaccgag agcctggagt    420

ccctcctgtc caagagccag gagcacgagc agcgcctggc cgccctgcag gggcgcctgg    480

aaggcctcgg gtcctcagag gcagaccagg atggcctggc cagcacggtg aggagcctgg    540

gcgagaccca gctggtgctc tacggtgacg tggaggagct gaagaggagt gtgggcgagc    600

tccccagcac cgtggaatca ctccagaagg tgcaggagca ggtgcacacg ctgctcagtc    660

aggaccaagc ccaggccgcc cgtctgcctc ctcaggactt cctggacaga ctttcttctc    720

tagacaacct gaaagcctca gtcagccaag tggaggcgga cttgaaaatg ctcaggactg    780

ctgtggacag tttggttgca tactcggtca aaatagaaac caacgagaac aatctggaat    840

cagccaaggg tttactagat gacctgagga atgatctgga taggttgttt gtgaaagtgg    900

agaagattca cgaaaaggtc taaatgaatt gcgtgtgcag ggcgcggatt taaagtccaa    960

tttctcatga ccaaaaatgt gtggtttttc cc                                  992


<210>  129
<211>  609
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (14)..(14)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (22)..(22)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (42)..(43)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (84)..(84)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (101)..(101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (104)..(104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (157)..(161)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (169)..(169)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (172)..(172)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (183)..(183)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (196)..(196)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (262)..(262)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (275)..(276)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (285)..(285)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (320)..(323)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (335)..(335)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (341)..(341)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (391)..(391)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (393)..(394)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (396)..(397)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (486)..(486)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (524)..(524)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (537)..(537)
<223>  n is a, c, g, or t

<400>  129
ncnaaatagn cttncaaacc cnaattcttt gggccccaaa annttaccta tgagaggatc     60

gcatcaccat aaccatcacg gatnctattt aggggacact ntanaatcgt cgacccacgc    120

gtccgcaaca ccacgatcac cagctatctg gtccagnnnn nttacttcnc cnaccaatac    180

atnacagaat actttntctc caagtgcatt tgattatgac acagaaaata tgaactctga    240

agatatttat agctctctta gnggggtcac tgaanntttt ttttntttca gcttccgtag    300

ccaagaagat atgaatgagn nnntgaaaag ggatnccccc naaagatgat ggcgattcaa    360

tgtgtggtgg tcctgggatg tctgacccaa nannannaag agatgctact gactcaagtc    420

aaacagctct tgataataaa gcttcattgc tccattcaat gcctactcac tcctctccac    480

gctctngaga ctataatcca tataactatt cagatagcat cagncccttc aacaagnctg    540

ccctcaagga agccatgttt gatgatgatg ctgaccagtt tcctgacgat ctttccctag    600

atcattctg                                                            609


<210>  130
<211>  1260
<212>  DNA
<213>  Homo sapiens

<400>  130
tttagataat actgacttac ctataaatag gcgtatcacg aggccctttc gtcttcacct     60

cgagaaatca taaaaaattt atttgctttg tgagcggata acaattataa tagattcaat    120

tgtgagcgga taacaatttc acacagaatt cattaaagag gagaaattaa ctatgagagg    180

atcgcatcac catcaccatc acggtcgacc cacgcgtccg cccctgctcc actgcgcgcc    240

cggcttctgc ttccccggcg tggcctgcat ccagacggag agcggcgcgc gctgcggccc    300

ctgccccgcg ggcttcacgg gcaacggctc gcactgcacc gacgtcaacg agtgcaacgc    360

ccacccctgc ttcccccgag tccgctgtat caacaccagc ccggggttcc gctgcgaggc    420

ttgcccgccg gggtacagcg gccccaccca ccagggcgtg gggctggctt tcgccaaggc    480

caacaagcag gtttgcacgg acatcaacga gtgtgagacc gggcaacata actgcgtccc    540

caactccgtg tgcatcaaca cccggggctc cttccagtgc ggcccgtgcc agcccggctt    600

cgtgggcgac caggcgtccg gctgccagcg gcgcgcacag cgcttctgcc ccgaacgctc    660

gcccagcgag tgccacgagc atgcaaactg cctcctaaaa cgcgatggct cgcggccggg    720

ctggggggcc cttggttggc cgggcaacgg aacctctgtg ggcccgaaac tgaacctaaa    780

gggttccccg aaaaaaaatt gccctgcccg gaaccccaaa ggccctaagg aatcatgcgg    840

gacggggccc cacccagggc cggagattcg ggaaccccaa tgccactcaa aaacccctgc    900

tacccaaatc ccaagaagaa cgtcatccac aaataataaa aaaacacccc ttatggaaga    960

aaacccatat cacctaatcc gcattaataa attgttgggg ccattcacac caatataacc   1020

cgctccataa caacacaatc acccacccaa caacataaca cacacaggtc actctctttt   1080

ccatcacaca ttattccact ctccgtcatt cttcctcctt actccctttc tttataacac   1140

atctcatccc cctctaccaa ccaaagcaca caacacccac aaagactccc aacagcacca   1200

ctcccctctt catacacgca accttccacg caaccaacac tagttactcg tacattctat   1260


<210>  131
<211>  927
<212>  DNA
<213>  Homo sapiens

<400>  131
atgagaggtc gcatcaccat caccatcacg gatcctattt aggtgacact atagaatcgt     60

cgacccacgc gtccgcccac gcgtccgatt acagtgagtt ctctggtgat gttgatagcc    120

tggaactggg ggacatggtc gagtatagct tgtccaaagg caaaggcaac aaagtcagtg    180

cagaaaaagt gaacaaaaca cactcagtga atggcattac tgaggaagct gatcccacca    240

tttactctgg caaagtaatt cgccccctga ggagtgttga tccaacacag actgagtacc    300

aaggaatgat tgagattgtg gaggagggcg atatgaaagg tgaggtctat ccatttggca    360

tcgttgggat ggccaacaaa ggggattgcc tgcagaaagg ggagagcgtc aagttccaat    420

tgtgtgtcct gggccaaaat gcacaaacta tggcttacaa catcacaccc ctgcgcaggg    480

ccacagtgga atgtgtgaaa gatcagtttg gcttcattaa ctatgaagta ggagatagca    540

agaagctctt tttccatgtg aaagaagttc aggatggcat tgagctacag gcaggagatg    600

aggtggagtt ctcagtgatt cttaatcagc gcactggcaa gtgcagcgcc tgtaatgttt    660

ggcgagtctg tgagggcccc aaggctgttg cagctcctcg acctgatcgg ttggtcaatc    720

gcttgaagaa tatcactctg gatgatgcca gtgctcctcg cctaatggtt cttcgtcagc    780

caaggggacc agataactca atggggtttg gtgcagaaag aaagatccgt caagctggtg    840

tcattgacta accacatcca caaagcacac cattaatcca ctatgatcaa gttgggggga    900

atctggtgaa gggttctgaa tatctcc                                        927


<210>  132
<211>  1027
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (817)..(817)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (829)..(829)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (835)..(835)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (842)..(842)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (849)..(849)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (851)..(851)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (862)..(862)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (875)..(875)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (903)..(903)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (918)..(918)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (928)..(928)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (931)..(931)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (955)..(955)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (963)..(963)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (979)..(979)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (994)..(994)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (999)..(999)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1011)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1014)..(1014)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1017)..(1017)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1022)..(1022)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1024)..(1024)
<223>  n is a, c, g, or t

<400>  132
naatagagaa attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cggatcagca gaggctgcag aggatgatga    120

gatccgcatg atcaatgagt tcccccgtgt ggccagtgtg gcctcctctc tggctgcccg    180

tggccctgac tcaggcatcc agcaggatgc agatggtctg agtgacacat cctgcgaacc    240

acctgcccct gacacctggt ataagggccg aaaggcaggg ctgctgctgc caggtgcagg    300

agccactctc tacagagagg aggggccccc agccactgcc acagccttcc tggggggctg    360

tggcctgagc cctgcaccca ctggggacta tggcttccca gcagatggca agccatgtgt    420

ggcaggtgcg ctgacagcca ttgtggccgg cgaggaggag ctccgtggca gctataactg    480

ggactacctg ctgagctggt gccctcagtt ccaaccactg gccagtgtct tcacagagat    540

cgctcggctc aaggatgaag ctcggccatg tcccccagct ccccgtatcg acccaccacc    600

cctcatcact gccgtggccc acccaggagc caagtctgtg ccccccaagc cagcaaacac    660

agctgcagcc cgggccatct tcccaccagc ttctcaccgc tcccccatca gccatgaagg    720

ctccctgtcc tcagctgcca tgtcccccag cttctcaccc tctctgtctc ctctggctgc    780

tcgctcaccc gttgtctcac catttggggt ggcccanggg tcccctcanc ctcancactc    840

ancgcaaant ntggccttgg anccacctga tgacncgaag ctgcacatct aactgtggcc    900

cangctgggc ccccaacntg ggaatgcnca nagtgtcccc aacgcaagcc cccanttttg    960

aancctgccc tggggcaanc ctccgaannn tgantgggnt acgggggaag nccnccnccn   1020

angnccc                                                             1027


<210>  133
<211>  1081
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (636)..(636)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (822)..(822)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (875)..(875)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (906)..(906)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (908)..(909)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (916)..(916)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (922)..(922)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (957)..(957)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (970)..(970)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (974)..(974)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (992)..(992)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (998)..(998)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1009)..(1009)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1011)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1017)..(1017)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1026)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1031)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1034)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1045)..(1045)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1051)..(1051)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1063)..(1063)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1075)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1078)..(1078)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1080)..(1080)
<223>  n is a, c, g, or t

<400>  133
agaaattaac tatgagagga tcgcatcacc atcaccatca cggatcctat ttaggtgaca     60

ctatagaatc gtcgacccac gcgtccgcgc tggtgtatga tgaggaaatc atggctggct    120

gggcacctga tgactctaac ctcaacacaa cctgcccctt ctgcgcctgc ccctttgtgc    180

ccctgctcag tgtccagacc cttgattccc ggcccagtgt ccccagcccc aaatctgctg    240

gtgccagtgg cagcaaagat gctcctgtcc ctggtggtcc tggccctgtg ctcagtgacc    300

gaaggctctg ccttgctctg gatgagcccc agctctgcaa cgggcacatg ggggtaaggg    360

ctgggccaaa ggggcatgag gaacgggaat gttgccctgt gtggggcctg tggggtgcca    420

gggagagatg ggcacatctc ttgcccttga gggcaagggg catcccaaaa gctgttggat    480

gtggtggctc agtgggaggc aaggctctgg ggatgtacat gccctctact gccctccccc    540

tttgtgcctg atagggagcc tcccggcggg ttgagagtgg ggcatgggca tacctgagcc    600

ccctggtgct gcgtaaggag ctggagtcgc tggtanagaa cgagggcagt gaggtgctgg    660

cgttgcctga actgccctct gcccacccca tcatcttctg gaaccttttg tggtatttcc    720

aacggctacg cctgcccagt attctaccag gcctggtgct ggcctcctgt gatgggcctt    780

cgcactccca ggccccatct ccttggctaa cccctgatcc anccctctgt tcaggtacgg    840

ctgctgtggg atgtactgac ccctgacccc aatanctgcc cacctctcta tgtgctctgg    900

aaggtncnna attgantctg gnatttggcc tgggtgggga agggtggggt cccatanccc    960

aaaaaggctn aatnaattct ggggggnctt tnttttcntt ttcatccang ncaaaantcc   1020

cccaancggg nggnnaaggn ccagnccctg naactgcatc ccnttaattt ggcnntgntn   1080

g                                                                   1081


<210>  134
<211>  1277
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (838)..(838)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (860)..(860)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (895)..(895)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (916)..(916)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (928)..(928)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (946)..(946)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (957)..(957)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (972)..(972)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (976)..(976)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (978)..(978)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (986)..(986)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (991)..(991)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (996)..(996)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1021)..(1021)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1039)..(1039)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1062)..(1063)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1069)..(1069)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1073)..(1073)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1080)..(1080)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1091)..(1091)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1095)..(1095)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1097)..(1097)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1109)..(1109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1115)..(1115)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1120)..(1120)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1126)..(1126)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1174)..(1175)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1177)..(1177)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1180)..(1180)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1187)..(1187)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1191)..(1191)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1197)..(1197)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1211)..(1211)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1222)..(1222)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1224)..(1224)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1234)..(1234)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1239)..(1239)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1244)..(1244)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1255)..(1257)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1260)..(1260)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1266)..(1266)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1269)..(1269)
<223>  n is a, c, g, or t

<400>  134
gatagagaaa attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cgccctcggc tcctccgccg tgatgctgtc    120

ccgatcccgc tgtgtgtctc gggcgttcag ccgctcgctc tccgccttcc agaaggggaa    180

ctgccctcta gggagacgtt ccctgcctgg ggtctcctta tgccagggac caggttaccc    240

taacagcagg aaggttgtca ttaacaacag tgtcttcagt gttcgctttt tcagaactac    300

agctgtatgc aaggatgact tggttacagt caaaacccca gcgtttgcag aatctgtcac    360

agagggagat gtcaggtggg agaaagctgt tggagacaca gttgcagaag atgaagtggt    420

ttgtgagatt gaaactgaca agacatctgt gcaggttcca tcaccagcaa atggcgtgat    480

tgaagctctt ttggtacctg atgggggaaa agtcgaagga ggcactccac ttttcacact    540

caggaaaact ggtgctgctc ctgctaaggc caagccggct gaagctcctg ctgctgcagc    600

cccaaaagca gaacctacag cagcggcagt tcctccccct gcagcaccca tacccactca    660

gatgccaccg gtgccctcgc cctcacaacc tccttctggc aaacctgtgt ctgcagtaaa    720

acccactgtt gccccaccac tagctgagcc aggagctggc aaaggtctgc gttcagaaca    780

tcgggagaaa atgaacagga tgcggcagcg cattgctcag cgtctgaagg aggcccanaa    840

tacatgtgca atgctgacan cttttaatga gattgacatg agtaacatcc agganatgag    900

ggctcggcac aaagangctt ttttgaanaa acataacctc aactangctt catgtcngca    960

tttgtgaagg cntcancntt tgcctngcag naacancctg nttgtaatgc agtgattgac   1020

nacccaccaa agaggtggng taaagggata aattgacttc anngttgcng ngnccccccn   1080

cggggtctgg nggtncngtc ctcnggaang ggaanctttn aatttnccaa aatgaacgga   1140

ccctccctga ctgggaaaaa aggcccaaaa aganntnccn ttaaaantga ngggggnact   1200

tcccataaaa nggaggcttt tngnccccct ttgnaaccna taanaccccc ccaannnccn   1260

ccgggnaang ggccctt                                                  1277


<210>  135
<211>  1018
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (832)..(832)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (836)..(836)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (840)..(840)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (859)..(859)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (865)..(865)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (871)..(871)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (877)..(877)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (882)..(882)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (894)..(894)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (899)..(899)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (903)..(904)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (920)..(920)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (935)..(935)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (945)..(945)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (949)..(949)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (953)..(953)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (961)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (967)..(968)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (973)..(973)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (990)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (992)..(992)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (994)..(994)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1000)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<400>  135
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccga gcagtcgccc tccagcaagc acagccccct    120

gaccgccagc gcccgtgggg actgtgtgcc gagccacggg caggacagtc gcaggcgcgg    180

ccggcggaag cgagcatctg cggggacgcc cagcttgagc gcaggcgtgt cccccaagcg    240

ccgagccctg ccgtccgtcg ctggcctttt cacacagcct tcggggtctc ccctcaacct    300

caactccatg gtcagtaaca tcaaccagcc cctggagatt acagccatct cgtccccgga    360

gacctccctg aagagctccc ctgtgcccta ccaggaccac gaccagcccc ccgtgctcaa    420

gaaggagcgg cctctgagcc agaccaatgg ggcacactac tccccactca cctcagacga    480

ggagccaggc tctgaggacg agcccagcag tgctcgaatt gagagaaaaa ttgcaacaat    540

ctccttagaa agcaaatctc ccccgaaaac cttggaaaat ggtggtggct tggcgggaag    600

gaagcccgcg cccgccggcg agccagtcaa tagcagcaag tggaagtcca ccttctcgcc    660

catctccgac atcggcctgg ccaagtcggc ggacagcccg ctgcaggcca gctccgccct    720

cagccagaac tccctgttca cgttccggcc cgccctggag gagccctctg ccgatgccaa    780

gctggccgct caccccagga aaggctttcc cggctccctg tcgggggctg anggantcan    840

cccgggcacc aaccctgcna acggntgcac nttcggnggg gnctggccgc gganctgant    900

tanncagctt cagtgatggn gcttctcttc cccanaaggg ccccnaggng gcnggcctga    960

nntcccnntg aanttccctc cnaacgnggn angnagggtn ngaanccaac cctttctg     1018


<210>  136
<211>  865
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (857)..(858)
<223>  n is a, c, g, or t

<400>  136
nnttatagag agaatactat gagaggatgc atcccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga ctctggacct tggctgtcac tcagttacaa cgtgtgatgc    120

cattagtgta ttggagaaag aacatgacta ctcagatgac cgttttgatt ttattcagtc    180

acatatccgg aagttttgtt tacagtatgg tgcggcactt atttacactc tcctgagaga    240

tcacaccaaa atacacttat gatataaata cttccttcat aaactatatg gatttcccta    300

tacgattcct gctgttgttg tggaaaagga tgcagtattt attccagcac ggtgggataa    360

tgataagaaa ataggactat tacatgaaga ttttcaaaca ttaaaggcag aagataattt    420

tgaagacatc ataactaacc cacctgttcg aacgtttgta catgagaagg atattatggc    480

ggaagatgat caggtgtttc ttatgaagct acagtccctt ttagcagagc aaccaccaac    540

tgcagctgga acgccggtgg atgcctcacc aagagtccca ggaggctccc cacgaacacc    600

agatatatct gtatcatcta atgttgccaa cgagtcaccc attcctgctg ggtcagacaa    660

cattgatcca tacatggaag ctggagctac gagtgaaggc gttctggcag atttcttcaa    720

cacgtgtgtg agtaacaaga ctggctctcc acgaggcact ggtgtgagtg gtgctagtcc    780

tgcacgtgga gctggaggtg aagcactggt ttacaccatc cacaaaagtc aggcaaaagc    840

tgtcgtagat gtctgcnnac tagac                                          865


<210>  137
<211>  844
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (569)..(569)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (702)..(702)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (790)..(790)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (793)..(793)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (800)..(800)
<223>  n is a, c, g, or t

<400>  137
ataagagata ctatgagagg acgcatcacc atcaccatca cggatcctat ttaggtgaca     60

ctatagaatc gtcgactctg gaccttggct gtcactcagt taaggtggtg tgtgtgggca    120

tgaattatgt ggaccactgc aaggaacaga acgtgcccgt gcccaaggag cccatcatct    180

tcagcaagtt tgccagctcc atcgtggggc cctatgatga ggtggtcctc ccaccacaga    240

gccaggaggt agattgggaa gtggagctgg ccgtggtcat tggaaagaaa ggcaagcaca    300

tcaaggccac agatgctatg gcccacgtgg ccggcttcac tgtggctcat gacgtgagtg    360

ctcgtgactg gcaaatgaga cgtaatggga aacaatggct gctgggaaaa accttcgaca    420

ccttctgccc tctgggccct gccttggtga ccaaggacag tgtagcagat ccacacaact    480

taaagatctg ctgccgagtg aatggggaag tggtccagag cggcaacacc aaccagatgg    540

tattcaaggc agaggacctg atagcctgng tctcccagtt tgttaccttt tacccagggg    600

atgtcatcct aactgggacc cccccaggtg tcggtgtatt caggaaacct cctgtctttc    660

tcaagaaggg ggatgaagtc cagtgtgaga ttgaagaact angtgtcaat catcacaagg    720

tggtgtgatg gctcctgcac aggccctgca cataggatga gggcatctgc tcccactcag    780

cctagcccan ggnaaagccn agtgacaggt gtggacaggt gcaagccctg caagcccgct    840

cttt                                                                 844


<210>  138
<211>  740
<212>  DNA
<213>  Homo sapiens

<400>  138
tactatgaga ggtcgcatca ccatcaccat cacggatcct atttaggtga cactatagaa     60

tcgtcgactc tggaccttgg ctgtcactca gttgggggca aatctctgct gtcgtcagca    120

tctgccacag taggtcatgg attgacggca gtcaaggaaa aagcaggagc cactctacgg    180

attcatggtg taaattctgg atcttctgaa ggagcccaac caaatactga aagcggagtc    240

cctgaaataa cagatgcagc cacagatcag ggccctgcag aaagcccacc cacctcccct    300

tcatcagcct ctcggggtat gctgtctgcc atcaccaatg tggttcaaaa cacaggtaaa    360

agtgtcttaa ctggaggcct tgatgcgttg gaattcatcg gcaagaaaac catgaatgtc    420

cttgcagaaa gtgacccggg ctttaagcgg accaagacgc tcatggagag aactgtttcc    480

ttgtctcaga tgttaaggga agctaaggag aaggagaagc agagactggc acagcagctc    540

acgatggaga gaaccgcgca ctacgggatg ctgtttgatg aatatcaagg cttgtcacac    600

ctggaagccc tggaaattct gtccaatgaa agcgaaagca aggtacttct gcactactcg    660

tttgaaatgg catgcttagt catgtgttgc ttaaacatga aagaaactgg aaaatctgcc    720

attaaaagat ctcatttttt                                                740


<210>  139
<211>  818
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (746)..(746)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (756)..(756)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (772)..(773)
<223>  n is a, c, g, or t

<400>  139
atactatgag aggtcgcatc ccatcaccat cacggatcct atttaggtga cactatagaa     60

tcgtcgactc tggaccttgg ctgtcactca gttaaaaaaa gtcacaaaga tgacagtgaa    120

ttagactttt cagctctttg tcctaagatt agcctcacgg ttgctgccaa agagttatct    180

gtgtctgaca cagacgtctc agaggtatcc tggactgata atgggacctt caacctttca    240

gaaggataca ctccacagac agacacttct gatgatcttg accgacccag tgaggaagtt    300

ttctctagag atctttcaga ttttccatct ctagaaaatg gcatgggaac aaatgatgaa    360

gatgaattaa gccttggttt gcccactgag ctcaagagaa agaaggaaca gttggacagt    420

ggtcacagac caagcaaaga gacgcaatca gcagctggtc tcacccttcc tctgaacagt    480

gaccaaacct ttcacctgat gagcaacctg gctggggatg ttatcacagc tgcagtgact    540

gcagctatca aagaccagtt agagggtgtg cagcaagcac tttctcaggc tgcccccatc    600

ccagaagagg acacagacac tgaagaaggt gatgactttg aactacttga ccagtcagag    660

ctggatcaaa ttgagagtga attgggactt acacaagacc aggaagcaga agcacagcaa    720

aataagaagt cttcaggttt cctttncaat ctgctnggag gcattaatct anngatcagc    780

ttgcacagag cacaaaaaca ccaaaaaatt tcaaacag                            818


<210>  140
<211>  844
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (694)..(695)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (734)..(734)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (744)..(744)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (834)..(834)
<223>  n is a, c, g, or t

<400>  140
atagagagat actatgagag gacgcatcac catcaccatc acggatccta tttaggtgac     60

actatagaat cgtcgactct ggaccttggc tgtcactcag ttaggaaagg agtgaaggaa    120

cccacgaagc ttttaaaaaa acattctacc caagtctacc tgggaccttc caagaagacg    180

tctgtgtcaa acgcaggcca atggctttat gaagaaaaac cacataaaat ggatttgctc    240

catgaaaatg gtcctcgtcc tggtcttcat gaaaatggaa tttcggacat cgatgaagag    300

ttcatcttga aacagtttga cattgactat gagaccaaac caagccatga tgcgctccac    360

acgatgaagc taaatcaggt tcctctggag ctacagcgta gtgtggggct cagtaaactg    420

caggagacag agttcttcca gaaactaggc tatgagagga aactccagaa accacagaat    480

ccttataagc caaagtgggt gaagatgagg tatggagcat ggtatttgaa ccccaagttg    540

tggaaaaagc aaagagtaga cgagcctctg gttgaccctg aggtctcaca taaggctcaa    600

gaggagaatt ttaaaaagga gctgcaggaa cagttccttg agaatatgta tatcgggaag    660

gaaatgtaac gtgcatgtaa taagactcct atannacgaa actcagcata gaagaatcgt    720

aagagaatga ttangcagat tttnatacta cgtacttggc tatttctctg tctccttttt    780

aagattaaca gagtttatga tgagtgtcca ctgtggatgt tcactttgac ttgncacatc    840

tgta                                                                 844


<210>  141
<211>  1133
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (843)..(843)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (915)..(915)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (931)..(931)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (942)..(942)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (947)..(947)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (957)..(957)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (965)..(965)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (993)..(993)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1009)..(1009)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1041)..(1041)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1054)..(1054)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1061)..(1061)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1064)..(1064)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1066)..(1066)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1073)..(1075)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1085)..(1085)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1089)..(1089)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1094)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1102)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1105)..(1105)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1111)..(1112)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1123)..(1123)
<223>  n is a, c, g, or t

<400>  141
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg gaaacgcaag tgcctgcgag agggcttcat    120

cactgaggac tgggaccagc ccgtggccga ctggaagatc ttctacttct tacggagcct    180

gcacaggaac ctcctgcaca acccgtgcgc tgaagagggg ttcgagttct ggagcctgga    240

tgtgaatgga ggcgatgagt ggaaggtgga ggatctctct cgagaccaga ggaaggaatt    300

ccccaatgac caggtcaaga aatacttcgt tacttcatat tagtaagatc cggggacttg    360

gggtagggga aagcccaaat caatttaccc tggggtctct cccaccctgg aaggggcagt    420

cctagcccct cactgcccta gtggtgagcc cagcccctcc cacccctctg cctgccccca    480

gcacctgcct caagtcccag gtggtggacc tcaaggccga agggtattgg gaggagctga    540

tggataccac acggccggac atcgaggtca aggactggtt cgcagccagg ccagattgcg    600

ggtccaagta ccagctgtgc gttcagctcc tgtcgtccgc gcacgcgcct ctggggacct    660

tccagccaga cccggcgacc atccagcaga agagcgatgc caagtggagg gaggtctccc    720

acacattctc caactacccg cccggcgtcc gctacatctg gtttcagcac ggcggcgtgg    780

acactcatta ctgggccggc tggtacggcc cgagggtcac caacagcagc atcaccatcg    840

ggnccccgct gccctgacac cccctgagcc cccatctgct gaaccctgac tggtaaacaa    900

ctgctgtcaa aaaanggctg ggcttgggaa ngggaagtgg angccangtg tccccanacc    960

tctanccttg cccctancac ctctttttgt gancctctca ngggggcanc cctcccatgn   1020

tggggtcggg ccactctccc naaagtcttg actnatgatg nccngnaacc ngnnnggccc   1080

tttcnaaang aacncngaaa tnggnagggc nntgttccct ggnccctcaa aat          1133


<210>  142
<211>  1323
<212>  DNA
<213>  Homo sapiens

<400>  142
attctgactt acctaaaaat aggcgtatcc gaggcccttt cgtcttcacc tcgagaaatc     60

ataaaaaatt tatttgcttt gtgagcggat aacaattata atagattcaa ttgtgagcgg    120

ataacaattt cacacagaat tcattaaaga ggagaaatta actatgagag gatcgcatca    180

ccatcaccat cacagtcgac ccacgcgtcc ggtccccaag cttggtgggg actttgttcg    240

ataccattac aactgttctt tgctggacgg cacccagctg ttcacctcgc atgactacgg    300

ggccccccag gaggcgactc tcggggccaa caaggtgatc gaaggcctgg acacgggcct    360

gcagggcatg tgtgtgggag agaggcggca gctcatcgtg cccccgcacc tggcccacgg    420

ggagagtgga gcccggggag tcccaagcag tgctgtgctg ctgtttgagg tggagctggt    480

gtcccgggag gatgggctgc ccacaggcta cctgtttgtg tggcacaagg accctcctgc    540

caacctgttt gaagacatgg acctcaacaa ggatggcgag gtccctccgg aggagttctc    600

caccttcatc aaggctcaag tgagtgatgg caaaggacgc ctcatgcctg ggcaggaccc    660

tgagaaaacc ataggagaca tgttccaaaa ccaagaccgc aaccaggacg gcaagatcac    720

agtccaacga gctcaagctg aagtccaatg acgaccacga gcgggtccac gacgacctct    780

gaagggcatg gaccccgtcc cagccctgaa aaccaacgcc cccctgcaag ggggcacctc    840

gcgccacaac cgacctaccg cacaaacccc tcacccaccg tcatctgtca tgcccacccc    900

caccaccaca ccaccacaac ccacccccct catcctacca cccaacaacc caataccaca    960

ccccacccca cccccataac cgcaaccgcc ccaccactct tcgcccacct cacccccacc   1020

aacccccacc actcacatct cgatcgcaca accaccacac caacccccct ttgcccataa   1080

cacacccccc ccacccaccc ccccatcccc cctcccctaa caccccccaa ccccccatgc   1140

ccccttacca ccaccaactg caaaaataac acacgtccag catctcatcc acacctaaaa   1200

ccctataaca tcatcacact accactaaaa actctcaaac cctttcgtca cccagtataa   1260

ctcccaacac acacccagca tctccatcgc tcccactctc cccacacccc acacccctca   1320

cac                                                                 1323


<210>  143
<211>  1198
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (16)..(16)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (180)..(180)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (627)..(627)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (748)..(748)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (801)..(801)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (803)..(803)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (884)..(884)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (896)..(896)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (959)..(959)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (961)..(961)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (995)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1044)..(1044)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1050)..(1050)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1055)..(1055)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1057)..(1057)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1073)..(1074)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1080)..(1080)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1083)..(1084)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1089)..(1089)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1093)..(1093)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1114)..(1114)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1126)..(1126)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1140)..(1140)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1143)..(1143)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1156)..(1156)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1162)..(1162)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1181)..(1182)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1188)..(1188)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1191)..(1191)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1195)..(1196)
<223>  n is a, c, g, or t

<400>  143
gaantagaga gattanctat gagaggatcg catcaccatc accatcacgg atcctattta     60

ggtgacacta tagaatcgtc gacccacgcg tccgcggacg cgtgggccac catctctagt    120

tcttcttcca ctaaaggaat aaagaggaaa gctacagaaa ttagcactgc agtggttcan    180

aggtcagcta ccattggcag ttctccagtt ctctatagcc agtcagctat agctacaggt    240

caccaggcag cagggattgg aaaccaggca acaggaattg gacatcagac aataccagtt    300

agccttccag cagcaggaat gggtcatcag gccagaggaa tgagcctgca gtcaaattac    360

cttggactag cggcagcacc tgcaattatg agttatgcag aatgttctgt cccaattgga    420

gtgactgctc cctcattgca gccagttcag gcccgaggtg ctgtgcctac cgctaccatt    480

atagaaccac caccaccacc tcctcctcct cctcctccac caccaccagc tcccaaaatg    540

ccaccacctg aaaagacaaa aaaaggaagg aaagacaagg caaagaagag taagaccaaa    600

atgccatctt tggtaaaaaa gtggcanagt atccagcgtg agttagatga agaggacaat    660

tctagttcca gtgaagagga tcgggaatca actgcacaga agcgaattga agagtggaaa    720

cagcagcagc tggttagtgg catggcanag agaaatgcta attttgaagc ccttcctgag    780

gattggagag caaggctgaa nanaaggaaa atggctccaa acacatagtt tttaagtttt    840

taaaactttt ttgtattatt gtttgttttg ggttcagttc aaangtctta accagntttt    900

attgtcaaat aaactataaa tgttatgggg ggaaatcttt ataaattttc ctgggcaana    960

ntgtatgcat acaaagtttt tcacttttgg gaaangtaat ttttcngttt ttgcnaaagg   1020

gatgaggtga atggaaatgc tttnaaccan gctgncnttt attcccaaat ggnnaaattn   1080

acnngttang ggnattaacc ccancntctt gganaaaatg gggctnagaa aaaaaacctn   1140

tgnaaggaat ccctgnaaaa antgaaaatt aatttccccc nnaaaaantg naatnnaa     1198


<210>  144
<211>  1229
<212>  DNA
<213>  Homo sapiens

<400>  144
ggaacgctta tactgaatta cctataaaaa ggcgtatccg aggccctttc gtcttcacct     60

cgagaaatca taaaaaattt atttgctttg tgagcggata acaattataa tagattcaat    120

tgtgagcgga taacaatttc acacagaatt cattaaagag gagaaattaa ctatgagagg    180

atcgcatcac cctcaccatc acggtcgacc cacgcgtccg gctgcctcgg gccgggccga    240

gaccccgcag aagcctccct acagctacat cgcgctcatc gccatggcga tccaggacgc    300

gcccgagcag agggtcacgc tcaacggcat ctaccagttc atcatggacc gcttcccctt    360

ctaccacgac aaccggcagg gctggcagaa cagcatccgc cacaacctct cgctcaacga    420

ctgcttcgtc aaggtgcccc gcgagaaagg gcggccgggc gggggcaact actggacgct    480

ggactcccgc tgcctgaaca tgtttgagaa cggcgactac cggcgacgga agaggcagcc    540

cctcccgggc cccccagtgc cacaaccgcg cagctacaca ggcccccacc aaccacgacg    600

tgaaccgcga acgagcaatc ccagcagccg atcgaccaca gtctgcccta ccggcctccc    660

cgtgcacccg accccaaagt ccacagaaca acaccattaa ccgcccaaaa tcacgcaagc    720

aaagagcacc gcccaacccc cacccagagc gacaacagac tggagcaatc ccacagcccc    780

ctccgaaccc gcgccagatg cccgcaaagc gaccagacca gaaccatcac aaacgtacac    840

caccctcaac cacgctgcga cacgacccgc aagcccggcc cgcagcgcgg ccctacccac    900

agcctacaat cggacgacca cagcctgcgc cgagcctatc agacaggccc cccccaccca    960

agcacagcaa ccaaccaccc aagaccacta cacagcatga ccacagagca cgattaccaa   1020

agagcccaca tcgagacgac agcataaccg gcaacactat ccacaaagtc ccggcaccgt   1080

gacccgacac ataaactggg gccgccccta ctccgacgag accaccagtt ccacccctac   1140

gcagcccccc caagaacaac aggctcaacg agcaccaagc ttgagcacca cgtccccccg   1200

ccaggcgatc ataacacaac gatcacgcg                                     1229


<210>  145
<211>  1206
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (861)..(861)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (884)..(884)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (902)..(902)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (915)..(915)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (942)..(942)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (945)..(945)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (986)..(986)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1029)..(1029)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1048)..(1048)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1081)..(1083)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1103)..(1103)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1105)..(1106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1113)..(1113)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1124)..(1126)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1129)..(1129)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1131)..(1131)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1133)..(1133)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1138)..(1138)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1145)..(1145)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1150)..(1150)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1169)..(1169)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1174)..(1175)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1177)..(1177)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1188)..(1188)
<223>  n is a, c, g, or t

<400>  145
cnaatagaga gattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgataactc caagtcagac tcctgccggg    120

aggtgactgt aactcccaac gcagcctggg gtggagaggg cagtctggga tgtggcattg    180

gctatgggta tctacaccgg atcccaactc agccccccag ctaccacaag aagccacctg    240

gcaccccacc accttctgct ctaccacttg gtgccccacc acctgatgct ctaccacctg    300

gacccacccc cgaggactct ccttccctgg agacaggttc caggcagagt gactacatgg    360

aggccctgct gcaggcacct ggctcctcca tggaggatcc ccttcctggg cctgggagtc    420

ccagccacag tgctccagac cctgatggac ttccccattt catggagact cctcttcagc    480

ccccacctcc agtgcagcga gttatggacc caggcttcct ggacgtgtcg ggaatttctc    540

tcttggacaa cagcaatgcc agtgtgtggc ccagcctgcc ctcttccaca gaactgacca    600

ccacagctgt ctcaacctca gggccagagg acatctgctc cagcagcagt tctcatgagc    660

ggggtggtga ggctacatgg tctgggtcag agtttgaggt ctccttcctg gacagcccag    720

gtgcccaagc ccaggcggac cacctgcctc agctgactct tcctgacagt ctcacctctg    780

cagcctcacc aaaagatggg ctgtccgccg agctgcttga agctcaggct gaggaggaac    840

cagcaagcac agagggccta natactggga cggaagctga gggnctggac agccaggccc    900

anatctctac cacanaataa caccctgggg ctgtgacaag gnccnatgat gaaatttcat    960

gaggcccaaa tgtgggcagg cagccngggc tgcactatgc ggtcangatt cttgctgctt   1020

tggtgggant gaaggcctca tgggtggnga aaaggggccc atgggccctt gggggaagaa   1080

nnnttttggc cgggaaccct cangnncagn ggntgggccc tgcnnnggnc ncnggggntt   1140

cccanaaagn aaacagggtt tggtcttant ccanntnaaa aaaaattnaa aaaaaaaggg   1200

tttctt                                                              1206


<210>  146
<211>  1028
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (613)..(613)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (746)..(746)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (827)..(827)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (835)..(835)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (857)..(857)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (865)..(865)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (871)..(871)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (879)..(879)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (901)..(901)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (908)..(908)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (917)..(917)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (936)..(936)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (939)..(939)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (944)..(944)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (948)..(948)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (959)..(959)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (964)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (969)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (975)..(975)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (991)..(991)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (993)..(994)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (998)..(1000)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1008)..(1008)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1026)
<223>  n is a, c, g, or t

<400>  146
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg ctacatcatt ctgtacaact accgccatgg    120

tggccgccag gggcagataa tctataactg gcagggtgcc cagtctaccc aggatgaggt    180

cgctgcatct gccatcctga ctgctcagct ggatgaggag ctgggaggta cccctgtcca    240

gagccgtgtg gtccaaggca aggagcccgc ccacctcatg agcctgtttg gtgggaagcc    300

catgatcatc tacaagggcg gcacctcccg cgagggcggg cagacagccc ctgccagcac    360

ccgcctcttc caggtccgcg ccaacagcgc tggagccacc cgggctgttg aggtattgcc    420

taaggctggt gcactgaact ccaacgatgc ctttgttctg aaaaccccct cagccgccta    480

cctgtgggtg ggtacaggag ccagcgaggc agagaagacg ggggcccagg agctgctcag    540

ggtgctgcgg gcccaacctg tgcaggtggc agaaggcagc gagccagatg gcttctggga    600

ggccctgggc ggnaaggctg cctaccgcac atccccacgg ttgaaggaca agaagatgga    660

tgcccatcct cctcgcctct ttgcctgctc caacaagatt ggacgttttg tgatcgaaga    720

ggttcctggt gagctcatgc aggaanacct ggcaacggat gacgtcatgc ttctggacac    780

ctgggaccag gtctttgttt gggttggaaa ggattctcaa gaagaanaaa agacngaagc    840

cttgacttct gctaagnggt acatngaaaa nggacccanc caatcgggaa tcgggggaac    900

ncccatcncc cgggggngaa aaaaagggtt tttganccnt cccntccntt ttggggggnt    960

tggntnccnt tgggntggga aaanaanaat nanngggnnn tgggggancc ccctttggan   1020

aagggncc                                                            1028


<210>  147
<211>  489
<212>  DNA
<213>  Homo sapiens

<400>  147
atggttctga gtccggcaga taaaaccaat gttaaagcag catggggtaa agttggtgca     60

catgccggtg aatatggtgc cgaagcactg gaacgtatgt ttctgagctt tccgaccacc    120

aaaacctatt ttccgcattt tgatctgagc catggtagcg cacaggttaa aggtcatggt    180

aaaaaagttg cagatgcact gaccaatgca gttgcacatg ttgatgatat gccgaatgcc    240

ctgagcgcac tgagcgatct gcacgcacat aaactgcgtg ttgatccggt taactttaaa    300

ctgctgagcc attgtctgct ggttaccctg gcagcacatc tgcctgcaga atttacaccg    360

gcagttcatg caagcctgga taaatttctg gcaagcgtta gcaccgttct gaccagcaaa    420

tatcgtagat cttaagcggc cgcggtacct ggagcacaag actggcctca tgggccttcc    480

gctcactgc                                                            489


<210>  148
<211>  633
<212>  DNA
<213>  Homo sapiens

<400>  148
aatataaaaa attatttgct ttgtgagcgg atacaattat aatagattaa ttgtgagcgg     60

ataacaattt cacacagaat tcattaaaga ggagaaatta actatgagag gatcgcatca    120

ccatcaccat cacggatcct atttaggtga cactatagaa tcgtcgaccc acgcgtccgc    180

acagactcag agagaaccca ccatggtgct gtctcctgcc gacaagacca acgtcaaggc    240

cgcctggggt aaggtcggcg cgcacgctgg cgagtatggt gcggaggccc tggagaggat    300

gttcctgtcc ttccccacca ccaagaccta cttcccgcac ttcgacctga gccacggctc    360

tgcccaggtt aagggccacg gcaagaaggt ggccgacgcg ctgaccaacg ccgtggcgca    420

cgtggacgac atgcccaacg cgctgtccgc cctgagcgac ctgcacgcgc acaagcttcg    480

ggtggacccg gtcaacttca agctcctaag ccactgcctg ctggtgaccc tggccgccca    540

cctccccgcc gagttcaccc ctgcggtgca cgcctccctg gacaagttcc tggcttctgt    600

gagcaccgtg ctgacctcca aataccgtta agc                                 633


<210>  149
<211>  590
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (433)..(433)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (501)..(501)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (538)..(539)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (550)..(550)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (552)..(553)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (556)..(556)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (563)..(564)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (568)..(569)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (571)..(571)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (581)..(581)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (590)..(590)
<223>  n is a, c, g, or t

<400>  149
tagagagatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc gggacgcgct tggccttgcc cgcgcccgct    120

cgcctcgtct cgcccggcct ccccgcgtcg cctcgtcgcc tgttccgcgc caggcatggc    180

ccccagcact gtggccgtgg agctgctcag ccccaaagag aaaaaccgac tgcggaagcc    240

ggtggtggag aagatgcgcc gcgaccgcat caacagcagc atcgagcagc tgaagctgct    300

gctggagcag gagttcgcgc ggcaccagcc caactccaag ctggagaagg ccgacatcct    360

ggagatggct gtcagctacc tgaagcacag caaagccttc gtcgccgccg ccggccccaa    420

gagcctgcac cangactaca gcgaaggcta ctcgtggtgc ctgcaggagg ccgtgcagtt    480

cctgacgctc cacgccgcca ncgacacgca aatgaagctg ctgtaccact tccagtgnnc    540

tccggccgcn cnngcngtgc ccnncaanna ncccaaggca ncaggcgccn               590


<210>  150
<211>  978
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (260)..(260)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (636)..(636)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (789)..(789)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (834)..(834)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (867)..(867)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (869)..(869)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (896)..(897)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (912)..(912)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (919)..(920)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (928)..(928)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (932)..(934)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (938)..(938)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (942)..(942)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (950)..(950)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (955)..(955)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (965)..(965)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (970)..(971)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (978)..(978)
<223>  n is a, c, g, or t

<400>  150
naatagagaa attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cgtgctctca aaagacattg aagctaagat    120

gatggccctg gaccgagagg tgcagtatct gctcaataag gccaagttta ccaagccccg    180

gccccggcct aaggacaaga atgggacccg ggcagagcca cccctcaatg ccagtgccag    240

tgaccagggg gagaaggtcn tccctccagc aggccagact gaagatgcag agcccatttc    300

agaacctgag aaagtagaga ctgcaggatc cgagccagga gacactgagc ctttggagtt    360

aggaggtcct ggagcagaac ctgaacagaa agaacaatcg acaggacaga agcggccttt    420

gaagaacgac gaactataac ccccacctct gttttcccca ttcatctcca cccccttccc    480

ccaccacttc tatttattta acatcgaggg ttgggggagg ggttggtcct gccctcggct    540

ggagttcctt tctcacccct gtgatttgga ggtgtggaga aggggaaggg agggacagct    600

cactggttcc ttctgcagta cctctgtggt taaaantgga aactgttctc ctccccagcc    660

ccactccctg ttccctaccc atataggccc taaatttggg aaaaatcact attaatttct    720

gaatcctttg cctgtgggta ggaaagaaaa tggctgccaa gtggctgatg ggtcccggtg    780

atggcaaang gtatcaggtt gccggggagt ttccactcct tctctggtga ttgnttcctt    840

ccctcccttt cctctcccaa ccatggnant gaacatccct tttcaagggc cagtgnntgg    900

caaagccttc antttaccnn ggtttggntt tnnnaagngc cntatctggn gcttntttcc    960

tcccntctgn nggctttn                                                  978


<210>  151
<211>  959
<212>  DNA
<213>  Homo sapiens

<400>  151
gaggatcgca tcaccatcac catcacggat cctatttagg tgacactata gaatcgtcga     60

cccacgcgtc cgggcccttt gtaccacata tcccatttga cttctatttg tgtgaaatgg    120

cctttccccg ggtcaagcca gcacctgatg aaacttcctt cagtgaggcc ttgctgaaga    180

ggaatcagga cctggctccc aattctgctg aacaggcatc tatcctttct ctggtgacaa    240

aaataaacaa tgtgattgat aatctgattg tggctccagg gacatttgaa gtgcaaattg    300

aagaagttcg acaggtggga tcctataaaa aggggacaat gactacagga cacaatgtgg    360

ctgacctggt ggtgatactc aagattctgc caacgttgga agctgttgct gccctgggga    420

acaaagtcgt ggaaagccta agagcacagg atccttctga agttttaacc atgctgacca    480

acgaaactgg ctttgaaatc agttcttctg atgctacagt gaagattctc attacaacag    540

tgccacccaa tcttcgaaaa ctggatccag aactccattt ggatatcaaa gtattgcaga    600

gtgccttagc agccatccga catgcccgct ggttcgagga aaatgcttct cagtccacag    660

ttaaagttct catcagacta ctgaaggact tgaggattcg ttttcctggc tttgagcccc    720

tcacaccctg gatccttgac ctactaggcc attatgctgt gatgaacaac cccaccagac    780

agcctttggc cctaaacgtt gcatacaggc gctgcttgca gattctggct gcaggactgt    840

tcctgccagg ttcagtgggt atcactgacc cctgtgagag tggcaacttt agagtacaca    900

cagtcatgac cctagaacag caggacatgg tctgctatac agctcagact ctcgtccga     959


<210>  152
<211>  1067
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (786)..(786)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (804)..(804)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (836)..(836)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (847)..(847)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (867)..(867)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (877)..(877)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (879)..(879)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (891)..(891)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (906)..(906)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (942)..(942)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (946)..(946)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (955)..(955)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (957)..(958)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (962)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (971)..(971)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (976)..(976)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (995)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1004)..(1004)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1007)..(1007)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1014)..(1014)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1016)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1025)..(1025)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1028)..(1028)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1032)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1051)..(1051)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1064)..(1064)
<223>  n is a, c, g, or t

<400>  152
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg gctgcctgga ggcagatgct cagccagcat    120

tgggcagccc ccgcttcctg ctcccctacc cccttcacat ggcagtagtt ctgggcaccc    180

cagcaaacca tattatgctc caggggcgcc cactccaaga cccctccatg ggaagctgga    240

atccctgcat ggctgtgtgc aggcattgct ccgggagcca gcccagccag ggctttggga    300

acagcttggg caactgtacg agtcagagca cgatagtgag gaggccacac gctgctacca    360

cagcgccctt cgatacggag gaagcttcgc tgagctgggg ccccgcattg gccgactgca    420

gcaggcccag ctctggaact ttcatactgg ctcctgccag caccgagcca aggtcctgcc    480

cccactggag caagtgtgga acttgctaca ccttgagcac aaacggaact atggagccaa    540

gcggggaggt cccccggtga agcgagctgc tgaaccccca gtggtgcagc ctgtgcctcc    600

tgcagcactc tcaggcccct caggggagga gggcctcagc cctggaggca agcgaaggag    660

aggctgcaac tctgaacaga ctggccttcc cccagggctg ccactgcctc caccaccatt    720

accaccacca ccaccaccac caccaccacc accaccacca ccacccctgc ctggcctggc    780

taccancccc ccatttcagc taancaagcc agggctgtgg agtaccctgc atgganatgc    840

ctggggnccc aaagcgcaag ggttcancac cccccananc gccaggagca ncggcactcg    900

ctgccntcac ccatatccat acccagctcc agcgtaaacc gngcancccc ctggncnncg    960

gntggtccgg ntgctncccc angnccangc ccccnccccc caanaanaaa aaancntggn   1020

tggcntgnct gncacccgtc ccccggaaat naccttaaaa aaanaaa                 1067


<210>  153
<211>  1244
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (949)..(949)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (960)..(960)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1003)..(1003)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1026)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1036)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1043)..(1043)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1053)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1080)..(1082)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1086)..(1087)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1091)..(1091)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1095)..(1095)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1103)..(1103)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1113)..(1113)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1116)..(1116)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1119)..(1119)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1125)..(1125)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1139)..(1139)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1141)..(1142)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1148)..(1149)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1160)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1162)..(1162)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1188)..(1188)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1195)..(1195)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1212)..(1212)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1228)..(1228)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1230)..(1230)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1236)..(1236)
<223>  n is a, c, g, or t

<400>  153
antagagaga ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gaagaaaatg cagccactga caatattgcc    120

ttcatgatta ccgaaaccac tgtccaggtt ctttccagtg gggaggtgca tgatattgtt    180

agccaaaagg gagaagacat acagacggtt aatatcgatg ccagaaaaga gatgaccccc    240

cgacaagaag ggactgacaa tgaggatcca gtcgtgtgcc tggacaagaa accagtgatc    300

atcattttcg atgagcccat ggacatccgg tctgcctata agagactttc aactatcttt    360

gaggaatgtg atgaggaatt agagagaatg atgatggagg aaaagataga ggaggaggaa    420

gaggaggaaa atggggattc tgtagtccag aataataaca cttcccagat gtctcataag    480

aaggtggccc caggcaatct tagaaccgga caacaggtgg aaacaaagtc acagccacac    540

tccctggcca cagagaccag aaacccagga ggacaggaaa tgaacagaac ggagctgaac    600

aagttcagcc acgtggattc tccaaattcg gaatgcaagg gtgaggacgc gaccgatgac    660

cagtttgaaa gccccaagaa aaagtttaaa ttcaaattcc ctaagaagca actcgccgct    720

ctcactcaag ccattcgcac cggaactaaa acagggaaga agactttgca agtggtagtc    780

tatgaagaag aggaagagga tggcaccctg aaacagcaca aagaagccaa gcgcttcgaa    840

atcgctaggt ctcaacctga agacacccct gaaaacacag tgaggaggca agagcagccc    900

agcatcgaga gtacatctcc gatttcagaa ctgatgaatt agaaaaacnc ctaccgaacn    960

ttggatagcc tggagcaaac cnttaacagc tcgaaataca tcngtgaaat gagtcccaag   1020

ccctanttga acctcntgtt ctnccacaaa atnctgttgc agttcctccc natagcccan   1080

nngccnnccc naccntgcta ntncggagaa ggnccntgnc caaancccct agtcaaacnt   1140

nncttccnna ggaactgggn tncggaaaag aaaaaccccc tgctttcnaa tcgcnaaacc   1200

cttaggaagg gnctggaatt attttttntn cggggntttt tttt                    1244


<210>  154
<211>  1012
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (833)..(833)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (840)..(840)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (847)..(847)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (856)..(856)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (861)..(861)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (880)..(880)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (883)..(883)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (886)..(886)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (898)..(898)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (920)..(920)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (935)..(935)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (941)..(941)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (950)..(950)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (955)..(955)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (970)..(971)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (976)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (979)..(980)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (986)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (991)..(992)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1000)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1003)..(1003)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1010)..(1010)
<223>  n is a, c, g, or t

<400>  154
taatagagaa attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cggctgtgac gactcagccc tggcacgaag    120

cccagcccgc ggcctgctgg gctctcggct gagcaaaatc tattcccagt ccaccctgtc    180

actgtccact gtggccaacg aggcccacaa taacctcggg gtgaagaggc ccacgtctcg    240

ggctccctcc ccgtcaggtc tcatgtcccc aagccgcctg cctggaagcc gcgaacggga    300

ctgggaaaat ggcagcaatg cctcctcccc agcgtcagtg cccgagtaca caggtccacg    360

gctgtacaaa gaacccagcg ccaagtccaa caagttcatc atccacaatg ccctatcaca    420

ctgctgcctg gcgggcaagg tgaacgaacc gcagaagaat cgcattctgg aggaaattga    480

gaaaagcaag gccaaccact tcctgatcct ctttcgcgac tcgagctgcc agttccgggc    540

gctctacacg ctgtcggggg agacagagga gctgtcgcgg ctggcagggt atgggccccg    600

gaccgtcacg cccgccatgg tggaaggcat ctacaagtac aactcggacc gcaagcgctt    660

cacccagatc cccgccaaga ccatgtccat gagcgtcgat gccttcacca tccagggaca    720

cctctggcag ggcaagaaac ccaccactcc caagaagggc ggcggcaccc ccaaatagcc    780

ccacccgggc ggtccacggg ccgggccctg tgtgctgcgg ccgctcccta tantgagtcn    840

tattaanctt aattanctga ncttggactc ctgttgatan atncantaat gacctcanaa    900

ctccatctgg atttgttcan aacgctcggt tgccnccggg ngtttttttn ttggngaaaa    960

tccaanctan nttggnnann attttnngga nntaaggaan ntnaaatggn aa           1012


<210>  155
<211>  941
<212>  DNA
<213>  Homo sapiens

<400>  155
catcaccatc accatcacgg atcctattta ggtgacacta tagaatcgtc gacccacgcg     60

tccgatgact cccagcttga aaaggcaaat ctcatagagc tggaagatga cagtcacagc    120

ggaaagcggg gaatcccaca tagcctgagt ggcctgcaag atccaattat agctcggatg    180

tccatttgtt cagaagacaa gaaaagccct tccgaatgca gcttgatagc cagcagccct    240

gaagaaaact ggcctgcatg ccagaaagcc tacaacctga accgaactcc cagcaccgtg    300

actctgaaca acaatagtgc tccagccaac agagccaatc aaaatttcga tgagatggag    360

ggaattaggg agacttctca agtcattttg aggcctagtt ccagtcccaa cccaaccact    420

attcagaatg agaatctaaa aagcatgaca cataagcgaa gccaacgttc aagttacaca    480

aggctctcca aagatcctcc ggagctccat gcagcagcct cttctgagag cacaggcttt    540

ggagaagaaa gagaaagcat tctttgagaa aaacaagcaa aggagaagag tgttactgta    600

cccttatgac agaattgtcc tggattttga ctccatccac gcccatcacc tttctacatt    660

ttgctgacag ataactaacc gatgatgagg ccgaggtaaa agagacatct gcagtgtgac    720

agaagggagc atgagaagca tggctcacca gccagcctct gtggtctttg taattagaag    780

cttcagaact cactaatact actgtacctt tcattggcgc attaccccat aaaacttttt    840

gagacgaggt gagatctgag tataaagata ggtcagaagt attttaaagg gcttaatgtg    900

ccaaaagaaa aaaagctaga gacccttttt gcaaacattt g                        941


<210>  156
<211>  958
<212>  DNA
<213>  Homo sapiens

<400>  156
tatgagagga tcgcatcacc atcaccatca cggatcctat ttaggtgaca ctatagaatc     60

gtcgacccac gcgtccgccc acgcgtccgc ccacgcgtcc ggcaaggtgg agctggaggc    120

caaggtggat gccctgaatg atgagatcaa cttcctcagg accctcaatg agacggagtt    180

gacagagctg cagtcccaga tctccgacac atctgtggtg ctgtccatgg acaacagtcg    240

ctccctggac ctggacggca tcatcgctga ggtcaaggca cagtatgagg agatggccaa    300

atgcagccgg gctgaggctg aagcctggta ccagaccaag tttgagaccc tccaggccca    360

ggctgggaag catggggacg acctccggaa tacccggaat gagatttcag agatgaaccg    420

ggccatccag aggctgcagg ctgagatcga caacatcaag aaccagcgtg ccaagttgga    480

ggccgccatt gccgaggctg aggagcgtgg ggagctggcg ctcaaggatg ctcgtgccaa    540

gcaggaggag ctggaagccg ccctgcagcg ggccaagcag gatatggcac ggcagctgcg    600

tgagtaccag gaactcatga gcgtgaagct ggccctggac atcgagatcg ccacctaccg    660

caagctgctg gagggcgagg agagccggtt ggctggagat ggagtgggag ccgtgaatat    720

ctctgtgatg aattccactg gtggcagtag cagtggcggt ggcattgggc tgaccctcgg    780

gggaaccatg ggcagcaatg ccctgagctt ctccagcagt gcgggtcctg gggctcctga    840

aggcttattc catccggacc gcatccgcca gtcgcaggag tgcccgcgac tgagccgcct    900

cccaccactc cactcctcca gccaccaccc acaatcacaa gaagattccc acccctgc      958


<210>  157
<211>  455
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (454)..(455)
<223>  n is a, c, g, or t

<400>  157
atagagagat actatgagag gtcgcatcac catcaccatc acggatccta tttaggtgac     60

actatagaat cgtcgactct ggaccttggc tgtcactcag tttataaaca aggaagtaaa    120

gggggcccct tgtgctctca gaactccaag catgaaacga ttttctgcca tttcagttcc    180

tgttatcgtg ctttgaggtg cactgaactg cagcaaaccc aggggatcca aggctacgtt    240

gaaaagcctt tgaccacagt gcagggagca gaagacatta atgacgtgat gtcgacacag    300

cccgcactca ggatcctcca ggaaaagaac acagagataa ccccggatcg atggtacttt    360

ttgaaaatgc tttattgcaa aagagtggct agggttttac aagggctatg aagaaacata    420

ttaaggttaa taaagctttt tattgagtgt ttann                               455


<210>  158
<211>  951
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (721)..(721)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (770)..(771)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (775)..(775)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (778)..(778)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (781)..(781)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (786)..(786)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (789)..(790)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (809)..(809)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (825)..(826)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (859)..(860)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (862)..(866)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (868)..(868)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (874)..(874)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (897)..(897)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (903)..(903)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (907)..(907)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (917)..(917)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (927)..(928)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (936)..(936)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (939)..(939)
<223>  n is a, c, g, or t

<400>  158
nnngggatat actgacttac ctataaatag gcgtatcacg aggccctttc gtcttcacct     60

cgagaaatca taaaaaattt atttgctttg tgagcggata acaattataa tagattcaat    120

tgtgagcgga taacaatttc acacagaatt cattaaagag gagaaattaa ctatgagagg    180

atcgcatcac catcaccatc acggtcgacc cacgcgtccg cacgcgtacc cgggcgccgg    240

cgtggcccac gacgagctgg gcccgcacgc tcacccgcac catcaccatc atcaccaagc    300

gtcgccgccg ccgtccagcg ccgctagccc ggcgcaacag ctgcccacta gccaccccgg    360

gcccgggccg cacgcgacgg cctcggcgac ggcggcgggc ggcaacggca gcgtggagga    420

ccgcttctcc gacgaccagc tcgtgtccat gtccgtgcgc gagctgaacc gccacctgcg    480

gggcttcacc aaggacgagg tgatccgcct gaagcagaag cggcggaccc tgaagaaccg    540

gggctacgcc cagtcttgca ggtataaacg cgtccagcag aagcaccacc tggagaatga    600

aaagacgcag ctcattcaac aggtggagca gctaagcaag aggtgtcccg gctggcccgc    660

aaaaaaacgc ctagaggtca agtgcgaaaa actcgccaac tccggctttc aggagagcgg    720

nttcatgaaa ggaaaccccc actactcaca agatttactg gtaatcgtan ncganctnga    780

ncctcnccnn aagaaatggc cagaagtgng ttctcggacc aaaannccta ccttacaggc    840

cacaatacat acaaccaann annnnnanac aaanagaaag acctcatgtc taaccantaa    900

atnccangca aaaacanata ctatccnnta acctcnggnt cccagtacat a             951


<210>  159
<211>  509
<212>  DNA
<213>  Homo sapiens

<400>  159
atgagcgttg atccgctgag cagcaaagca ctgaaaatta aacgcgaact gagcgaaaat     60

acaccgcatc tgtctgatga agcactgatg ggtctgagcg ttcgtgaact gaatcgtcat    120

ctgcgtggtc tgagcgcaga agaagttacc cgtctgaaac agcgtcgtcg taccctgaaa    180

aatcgtggtt atgcagcaag ctgtcgtgtt aaacgtgttt gccagaaaga agaactgcag    240

aaacagaaaa gcgaactgga acgtgaagtt gataaactgg cacgtgaaaa tgcagcaatg    300

cgtctggaac tggatgcact gcgtggtaaa tgtgaagcac tgcagggttt tgcacgtagc    360

gttgcagcag cacgtggtcc ggcaaccctg gttgcaccgg caagcgttat taccattgtt    420

aaaagcacac cgggtagcgg tagcggtccg gcacatggtc ctgatccggc tcatggtccg    480

gcaagctgta gctaagcggc cgcgagctc                                      509


<210>  160
<211>  1179
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (774)..(774)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (838)..(838)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (872)..(872)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (892)..(892)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (898)..(898)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (925)..(925)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (938)..(938)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (967)..(967)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(983)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (994)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1002)..(1003)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1012)..(1012)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1021)..(1021)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1062)..(1063)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1076)..(1076)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1092)..(1092)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1094)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1097)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1121)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1129)..(1129)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1131)..(1132)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1138)..(1138)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1144)..(1144)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1146)..(1146)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1150)..(1150)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1158)..(1158)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1171)..(1172)
<223>  n is a, c, g, or t

<400>  160
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc gcagtctctg tgcgttgaag ccggagaccg    120

cggcggcctc agcgaggacc ctccgccccg gagccgccgg ccggagccgc agcctctgcc    180

gcagcgcccc cgccacctgt cccctccccc tccgcctccg ccggagccgc ctcgtgcact    240

ctggggtatg gccgtcaatg tgtactccac atctgtgacc agtgaaaatc tgagtcgcca    300

tgatatgctt gcatgggtca acgactccct gcacctcaac tataccaaga tagaacagct    360

ttgttcaggg gcagcctact gccagttcat ggacatgctc ttccccggct gtgtgcactt    420

gaggaaagtg aagttccagg ccaaactaga gcatgaatac atccacaact tcaaggtgct    480

gcaagcagct ttcaagaaga tgggtgttga caaaatcatt cctgtagaga aattagtgaa    540

aggaaaattc caagataatt ttgagtttat tcagtggttt aagaaattct ttgacgcaaa    600

ctatgatgga aaggattaca accctctgct ggcgcggcag ggccaggacg tagcgccacc    660

tcctaaccca ggtgatcaga tcttcaacaa atccaagaaa ctcattggca cagcagttcc    720

acagaggacg tcccccacag gcccaaaaaa catgcagacc tctggccggc tgancaatgt    780

ggcccccccc tgcattctcc ggaagaatcc tccatcagcc cgaaatggcg gccatganac    840

tgatgcccaa aattcttgaa ctcaaccaac anctggtgga cttgaaactg anagtggnat    900

gggctggaaa aaagaaagtg acttntactt cagcaaantt cgtgaaatcg agctcatctg    960

ccaggancat gaaagtgaaa anngccctgt tatnncagga annttggcat cntttatgcc   1020

naaaaagaaa ggattcccac cccctggagg agaatgaaaa tnnaaaaacc tccacnaaaa   1080

aaaaccggga cnantnntgg agggggggcg cctcccctaa nagggaggnc nnattaanct   1140

ttantnaacn gaaacttngg aaccccggtt nnaaaaatc                          1179


<210>  161
<211>  1280
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (876)..(876)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (944)..(944)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (986)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1027)..(1027)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1048)..(1048)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1058)..(1058)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1087)..(1088)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1111)..(1111)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1117)..(1117)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1124)..(1124)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1133)..(1133)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1136)..(1137)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1142)..(1142)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1144)..(1144)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1161)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1164)..(1164)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1166)..(1166)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1172)..(1172)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1177)..(1177)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1183)..(1183)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1187)..(1187)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1189)..(1189)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1191)..(1191)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1208)..(1208)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1225)..(1225)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1228)..(1228)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1256)..(1256)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1258)..(1258)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1263)..(1263)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1272)..(1272)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1278)..(1278)
<223>  n is a, c, g, or t

<400>  161
antagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gcccacgcgt ccggcatcac agatggcaac    120

atgccaggga ccaggcctgc cagccgccgg atgcagcagg ctggagctgt ctcccccttt    180

gggatgctgg gaatgtcggg tggtttcatg gacatgtttg ggatgatgaa tgacatgatt    240

ggaaacatgg aacacatgac agctggaggc aattgccaga ccttctcatc ttccactgtc    300

atctcctact ccaatacggg tgatggtgcc cccaaggtct accaagagac atcagagatg    360

cgctcggcac caggcgggat ccgggagaca cggaggactg ttcgggattc agacagtgga    420

ctggagcaga tgtccattgg gcatcacatc cgggacaggg ctcacatcct ccagcgctcc    480

cgaaaccatc gcacggggga ccaggaggag cggcaggact atatcaacct ggatgagagt    540

gaggccgcag cgtttgatga cgagtggcgg cgggagacct cccgattccg gcagcagcgt    600

cccctggagt ttcggcggct tgagtcctca ggggctgggg gacgaagggc ggaggggcct    660

ccccgcctgg ccatccaggg acctgaggac tccccttccc gacagtcccg ccgctatgac    720

tggtgagggc cccgggccct cagcctctct tgtacaggct gagaggctga aaaatcatcc    780

cctgaataac tttttcctct cgattcccat ccccaatttt aatattaaat taacaggcaa    840

gccggccccc acctctccct ggggggtctc aggganaacc tttcacggca ccctttccct    900

accttttcct tctttaatct cctggtttac cattgatgac ttcncctctt gcatctactg    960

aatttgattt ttcattntgc cnctcnntct ttcaaacccc ctcacntttt ccatcctaat   1020

cctggcntgg cattgaaagg gtcatgcntt tttggggnga acctcttggg tttaagggcc   1080

ccctccnntc ctcaantnac ctggattttt ncccccnctt cctnaaaacc ccnctnnagg   1140

gncntacccc tatttagggn ntgngnaaga anaaaanggt tcnaaantnc ntcccccccc   1200

ccggcccnaa aataaaaaat ttccnacncc ctttccccct ttttttttta tttgcncntt   1260

tantggggtt tnggaaangg                                               1280


<210>  162
<211>  958
<212>  DNA
<213>  Homo sapiens

<400>  162
taactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt gacactatag     60

aatcgtcgac ccacgcgtcc gcagaaaagc tcacagatca ggtgatgcag aatcctcgag    120

ttctggcagc tttacaggag cgacttgaca atgtccctca caccccttcc agctacatcg    180

aaactttacc taaagcagta aaaagaagaa ttaatgcatt gaaacaactt caggtgagat    240

gtgctcacat agaagccaag ttctatgaag aggtacatga cttggaaaga aagtatgcag    300

cgctatacca gcctctcttt gacaagagaa gagaatttat caccggcgat gttgaaccaa    360

cagatgcgga atcggaatgg cacagtgaaa atgaagagga agagaaattg gctggagaca    420

tgaaaagtaa agtagtcgtc acagaaaaag cagcggcaac ggctgaagag ccagatccca    480

aaggaattcc agagttctgg tttaccatct tcagaaatgt ggacatgctg agtgaattag    540

tccaggaata tgatgaacca atcttgaaac acctgcagga tattaaagtg aaattttctg    600

accctggaca gcctatgtct tttgtgttag agttccactt tgaacccaac gactacttta    660

ccaactcagt cctgacaaaa acctacaaga tgaaatcaga accagataag gctgatccct    720

tttcctttga aggtcctgag attgtggact gtgacgggtg tactattgac tggaagaaag    780

gaaagaatgt tactgtcaaa accatcaaga aaaagcagaa gcataagggt cgaggcactg    840

ttagaacaat tacgaaacaa gtacccaatg agtccttttt caacttcttc aatccattga    900

aagcatccgg ggatggagaa tcactggatg aagattctga attcacatta gcctctga      958


<210>  163
<211>  1458
<212>  DNA
<213>  Homo sapiens

<400>  163
ccctcccccc cctaggcata cttgagagga tcgcatcacc atcaccatca cggtcgaccc     60

acgcgtccgg cgatggagtg tgtctggaag cagaagctat atgagccagt ggtgatccct    120

gtgggcaggc tgtttcgacc aaatgagaga caagtggctc agctggccaa gaaggattac    180

ctaggcaagg cgacggtcgt ggcatctgtg gtggatcaag acagtttctc tgggtttgcc    240

cctctgcaac cacaggcagc tgagcctcca cccagaccga aaaccccaga gatcttcagg    300

gctctggaag gggaggctca ccgtgtgcta tttgggtttg tgcctgagac aaaagaagag    360

ctccaggtca tgccagggaa cattgtcttt gtcttgaaga agggcaatga taactgggcc    420

acggtcatgt tcaacgggca gaaggggctt gttccctgca actaccttga accagttgag    480

ctgcggatcc accctcagca gcagccccag gaggaaagct ctccgcagtc cgacatccca    540

gctcctccta gttccaaagc ccctggaaga ccccagctgt caccaggcca gaaacaaaaa    600

gaagagccta aggaagtgaa gctcagtgtt cccatgccct acacactcaa ggtgcactac    660

aagtacacgg tagccatgaa tactccaccc gggctcccct acagccaggt ccgcgacttg    720

ctgctaaaga aacttcacct ccgcctgacc actcccacct tccacctatc cccctcgctc    780

acaccttgcc cccgccgccc cttccacccc caacctacct atatccccga ccaccatccc    840

ccacttcccg cctcgaccca ccgcactcaa aaaccaaaat gcactcccca acattaccca    900

ttaacccccc caccctcata atctgatcac ctcacccatt ccatccacct tcctcttccc    960

acaaccacac caataccacc acccccccta cacatccaac cctccccaaa cacattattc   1020

cccacatccc ccattcactt ccacccaaac cacacaactc cttaacatca cttacttccc   1080

aaatcaacac tgctcctcac aaatacaccc tgcacccccc cctcaccgcc caacacctcc   1140

ctctacaatc cctccctcac accccaccta cacccccctc cacaccaccc acccctcatc   1200

atatctccca tcactcatct ccccccttca ccaccactca cacccctgcc accacgcacc   1260

ccctctcacc accactcaca cccacacatc catcacttca cctcccttct cctcaactaa   1320

ccccctccca cccctcctca ccaacactta ccttcaccac cccaccccta aaccctaccc   1380

tccccccact cactctctac cacatgctat ccccctcccc ctccaccacc tcacactact   1440

accacctcat tacctctt                                                 1458


<210>  164
<211>  904
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (797)..(797)
<223>  n is a, c, g, or t

<400>  164
tatgagaggt cgcatcacca tcaccatcac ggatcctatt taggtgacac tatagaatcg     60

tcgactctgg accttggctg tcactcagtt taccccaacc agttgacagt gaactcatta    120

aattcagatg ccacagtcaa cacagatttt ggtgatgaat tttattctgc tttcatagct    180

gagcccagta tcagcaacag catgccctca cctgctactt taagccattc actctctgaa    240

cttctaaatg ggcccattga tgtttctgat ctatcacttt gcaaagcttt caaccaaaac    300

caccctgaaa gcacagcaga attcaatgat tctgactccg gcatttcact aaacacaagt    360

cccagtgtgg catcaccaga acactcagtg gaatcttcca gctatggaga cacactactt    420

ggcctcagtg attctgaagt ggaagagcta gatagtgccc ctggaagtgt caaacagaat    480

ggtcctaaaa caccagtaca ttcttctggg gatatggtac aacccttgtc accatctcag    540

gggcagagca ctcacgtgca tgatgcccaa tgtgagaaca caccagagaa agaattgcct    600

gtaagtcctg gtcatcggaa aaccccattc acaaaagaca aacattcaag ccgcttggag    660

gctcatctca caagagatga acttagggca aaagctctcc atatcccatt ccctgtagaa    720

aaatcattaa cctccctgtt gttgacttca cgaaatgatg tccaaagagc agttcaatga    780

aggctcactt gccatanttc gggatatcgt aggaggggta agataaagtg gctgctcaga    840

atgcagaaaa gaaactggaa atatatagac tagagcagat ttaatctttg aagatgaaag    900

aaaa                                                                 904


<210>  165
<211>  1199
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (815)..(815)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (863)..(863)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (870)..(870)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (882)..(882)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (924)..(924)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (934)..(934)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (961)..(961)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (965)..(965)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (979)..(979)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (995)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1031)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1042)..(1042)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1054)..(1054)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1061)..(1061)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1064)..(1064)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1079)..(1079)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1108)..(1108)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1123)..(1125)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1129)..(1129)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1146)..(1146)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1148)..(1148)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1152)..(1152)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1157)..(1157)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1161)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1166)..(1167)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1170)..(1170)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1177)..(1177)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1180)..(1180)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1187)..(1187)
<223>  n is a, c, g, or t

<400>  165
ntagagaaat tactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg cggacgcgtg ggcggacgcg tgggtgcgaa    120

gtgagctctc tggcctcccc ttctattgga atttccactg catgctagct agtccttccc    180

tggtctccca acatttgatt cgtcctctga tgggcatgag tctggcatta cagtgccaag    240

tgagggagct agcaacgtta cttcatatga aagacctaga gatccaagac taccaggaga    300

gtggggctac gctgattcga gatcgattga agacagaacc atttgaagaa aattccttct    360

tggaacaatt tatgatagag aaactgccag aggcatgcag cattggtgat ggaaagccct    420

ttgtcatgaa tctgcaggat ctgtatatgg cagtcaccac acaagaggtc caagtgggac    480

agaagcatca aggcgctgga gatcctcata cctcaaacag tgcttccctg caaggaatcg    540

atagccaatg tgtaaaccag ccagaacaac tggtctcctc agccccaacc ctctcagcac    600

ctgagaaaga gtccacgggt acttcaggcc ctctgcagag acctcagctg tcaaaggtca    660

agaggaagaa gccaaggggt ctcttcagtt aatctgttgt ggcctcagct gctgaggatg    720

gacttggaga atagcttcca agcttcacct tgaaagaagc ttacatggca gcaatatttc    780

taaaaatagt gatacagtca gaggcctcct gtaanggcga gagaactgaa gttgatgttg    840

acaggcccac agggaattgg ccntccctgn ttcaagtgga anccagtctc tgagaatccc    900

gtgctctcct ctcttttggt ggangtttct gtangttcag gtttctacca tggactttta    960

ngtanatagg ggcaagtcng ccanaaagca ccacncacct cagggaagcc cttgtctaac   1020

cttttcccta ncggntctct anccagccag cccnaaaant nctncaaaaa cccccttcnc   1080

tcttttgcag ggaaaaaaag cccnccantc ccggcttttg gannncttnt gctgggaaac   1140

caaaancnaa tnccttnctn nctggnnccn ccccttntgn tcccggnaaa atccacccc    1199


<210>  166
<211>  1325
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (872)..(872)
<223>  n is a, c, g, or t

<400>  166
nncccgccta cccccctaag aatactagag aggacgcatc accatcacca tcacggtcga     60

cccacgcgtc cggccaacca gaccctgacc gagctggacc tgagcttcaa tgtgctcacg    120

gatgctggag ccaaacacct ttgccagaga ctgagacagc cgagctgcaa gctacagcga    180

ctgcagctgg tcagctgtgg cctcacgtct gactgctgcc aggacctggc ctctgtgctt    240

agtgccagcc ccagcctgaa ggagctagac ctgcagcaga acaacctgga tgacgttggc    300

gtgcgactgc tctgtgaggg gctcaggcat cctgcctgca aactcatacg cctggggctg    360

gaccagacaa ctctgagtga tgagatgagg caggaactga gggccctgga gcaggagaaa    420

cctcagctgc tcatcttcag cagacggaaa ccaagtgtga tgacccctac tgagggcctg    480

gatacgggag agatgagtaa tagcacatcc tcactcaagc ggcagagact cggatcagag    540

agggcggctt cccatgttgc tcaggctaat ctcaaactcc tggacgtgag caagatcttc    600

ccaattgctg agattgcagg caagagccac gaggaaagct ccccagaggt agtaccggtg    660

gaactcttgt gcatgccttc tcctgcctct caaggggacc tgcatacgaa gcctttgggg    720

actgacgatg acttctgggg ccccacgggg cctgtggcta ctgaggtagt tgacaaagaa    780

aagaacttgt accgagttca cttccctgta gctggctcct accgctggcc caacacgggt    840

ctctgctttg tgatgagaga agcggtgacc gntgagattg aatctgtgtg tgggaccagt    900

tcccgggtga gatcaaccca cagcacagct ggatggtggc aagccctctg ctggacatca    960

aagctgaccc cgaagctgtg gaaactgtgc ccccccttca ctttggggct ctccaggaac   1020

tggaactccg ctaatcaaac cccgaaaaaa acaactggtc cccgaaattc tacttggcca   1080

ctgggaaaca gggacccggc cccaatgcaa accaaacaaa ttaactctcg gggggcgagc   1140

ctggtgaaaa ccgaaaaacc ccagcctgca aaaaccacga ccccaccacc ccgaaaacca   1200

aaccttcccc cctgaacccc cccatctacc acatatgata cacaaccaaa acatctccct   1260

acaccaacac cactgcgaaa gcctcctcac aaactatcag tacacgcccg acccacacaa   1320

ccacc                                                               1325


<210>  167
<211>  1133
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (808)..(808)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (823)..(823)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (859)..(859)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (861)..(861)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (866)..(866)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (879)..(879)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (887)..(887)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (897)..(897)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (918)..(918)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (947)..(947)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (952)..(952)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (969)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (974)..(974)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (981)..(981)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (991)..(991)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1014)..(1014)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1017)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1022)..(1022)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1034)..(1034)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1049)..(1050)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1054)..(1054)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1057)..(1057)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1065)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1074)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1081)..(1083)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1088)..(1089)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1105)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1108)..(1108)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1112)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1124)..(1124)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1132)..(1132)
<223>  n is a, c, g, or t

<400>  167
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg gaccaggcag ccactttcct ggtgctctct    120

gggcccagct ggtgctgtag ggccacgcag gcaggggcgt caaggggttt ctctgcccaa    180

ggaagacaga acatggagaa ccgtcagggc aggaacccca cagactgtcc cttccagccc    240

acactctgcc acctcctggc cctgtcccaa ttctgagcca aggcctcccc gaggcagaag    300

ttgcctggtc ctctgtcccc acagtgacct gactgggggt gagggagaag gaggagagag    360

cccatgtgtg gtgtgtgtgc ccctgagaac ttcgtggtga ctgcctttgg gagcccgcag    420

gtggccagag gcaggggtag ctgagttcct ggagacccct tttttgcccc caggttcccc    480

agagggcaac gccatcagta gcagtgtggt gtttcaggca gagctctggc caggctgtgc    540

cagtgtgtcc cggacgcatc actaaggaag agagagttta tttagtcaac tggcccaagg    600

cagcgaggct tctacagtcc cacaccccat agccgcctgg gctggggctt actgggggct    660

gaaggttctg gacatgaaca agggtcaggt agaagagaaa ggcttcccct acaccccagc    720

ctcctgctgt cccctgaagc ccaggactgc gttgtatgct ttccatccac tcaccttacc    780

ccatagcatc ttgcggccca aaaaccanag ccatttgtct canaccctaa atcaataatc    840

acaaacccca aaacgggana nagcantgaa aacatgcang gctgtgnacg ggggaanggt    900

tgtggcgggt gttctgangc tgaaaagaca cctatatgcg tatttcntct anacacatca    960

ccccccttnt atantcttaa nccatgacta ncctggnggc gtgtaaattt ctgnccnntt   1020

tnaccccctc atgngcttct tctgaaaann gaangtnant gtttnaaaac tggnaaaatt   1080

nnnccccnnt tattgnaaaa aaanntgnaa ancttggaaa tttntttttt tnc          1133


<210>  168
<211>  885
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (17)..(17)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (25)..(25)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (59)..(59)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (253)..(253)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (256)..(257)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (744)..(744)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (860)..(860)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (868)..(868)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (874)..(874)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (876)..(876)
<223>  n is a, c, g, or t

<400>  168
ttcnttaaag aggaganatt aactntgaga ggatcgcatc accatcacca tcacggatnc     60

tatttaggtg acactataga atcgtcgacc cacgcgtccg gaaggccctc aggaaaaggc    120

attgttgagt tctcagggaa gccagctgct cggaaagctc tggacagatg cagtgaaggc    180

tccttcctgc taaccacatt tcctcgtcct gtgactgtgg agcccatgga ccagttagat    240

gatgaagagg ganttnnaga gaagctggtt ataaaaaacc agcaatttca caaggaacga    300

gagcagccac ccagatttgc acagcctggc tcctttgagt atgaatatgc catgcgctgg    360

aaggcactca ttgagatgga gaagcagcag caggaccaag tggaccgcaa catcaaggag    420

gctcgtgaga agctggagat ggagatggaa gctgcacgcc atgagcacca ggtcatgcta    480

atgagacagg atttgatgag gcgccaagaa gaacttcgga ggatggaaga gctgcacaac    540

caagaggtgc aaaaacgaaa gcaactggag ctcaggcagg aggaagagcg caggcgccgt    600

gaagaagaga tgcggcggca gcaagaagaa atgatgcggc gacagcagga aggattcaag    660

ggaaccttcc ctgatgcgag agagcaggag attcggatgg gtcagatggc tatgggaggt    720

gctatgggca taaacaacag aggngccatg ccccctgctc ctgtgccagc tggtacccca    780

gctcctccag gacctggcca ctatgatgcc cggtggaact ttggggattg accccaccaa    840

caactgaacg ctttggtcan gctgcttnaa tggnangaat tgggg                    885


<210>  169
<211>  838
<212>  DNA
<213>  Homo sapiens

<400>  169
attactatga gaggtcgcat caccatcaca tcacggatcc tatttaggtg acactataga     60

atcgtcgact ctggaccttg gctgtcactc agttaaaagg gatagccata tgaaacagct    120

cctcctcatc caagagagat ggaaaagggc ccagcgtgaa gaaagattga aagcccagca    180

gaacacagac aaggatgcag ctgcccatct tcagacatct cacaaaccct ctgcagagga    240

tgcagagggc cagagtcccc tttctcagaa gtacagccct tccacagaga aatgcctgcc    300

tgagattcag gggatctttg acagggatcc agacacacta ctttatttac ttcagcaaaa    360

gagtgagcca gcagagccat gtattggaag caaagcccca aaagatgata aaacaattat    420

agaggagcag gcaaccaaaa ttgcagattt gaagaggcat gtggaattcc ttgtggctga    480

gaatgaaaga ttaaggaaag aaaataaaca actaaaggcc gaaaaggcca gacttctaaa    540

aggtccaata gaaaaggagc tggatgtaga tgctgatttt gtagaaacgt cagagttatg    600

gagcttgcca ccacatgcag aaactgctac tgcctcctca acctggcaga agttcgcagc    660

aaatactggg aaagccaagg acattccaat ccccaatctt cctcccttgg attttccatc    720

tccagaactt cctcttatgg agctctctga ggatattctg aaaggattta tgaataatta    780

aaatggaagg ccacagaaaa ggggaaaaga agaaaatata cagtaatcgt taatccag      838


<210>  170
<211>  1401
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (9)..(10)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<400>  170
acgcccncnn cctaagagat actagagagg atcgcatcac catcaccatc acggtcgacc     60

cacgcgtccg cccacgcgtc cgggccgccc agcggcgccg caggggaagc caggccggca    120

gccgcgcgct ccccagccgg ccaccaatcc cgccctcccc ggctcctccg gacctcctcg    180

gcaggcggcg gcggggcctg cctgtgcgct ctgcgcccgc ccgcgcctac cctccatggc    240

gtttatccgg aagaagcagc aggagcagca gctgcagctc tactccaagg agagattttc    300

cttgctgctg cttaacttgg aggagtacta ctttgaacag catagagcca atcacatttt    360

gcacaagggc agtcaccatg aaaggaaaat cagaggctcc ttaaaaatat gttcaaaatc    420

ggtgattttt gaaccagatt caatatccca gcccatcatc aagattcctt tgagagactg    480

tataaaaata ggaaagcatg gagaaaatgg agccaataga cacttcacaa aggcaaaatc    540

tgggggtatt tcactcattt tcagtcaggt atatttcatt aaagaacata atgttgttgc    600

accatataaa atagaaaggg gcaaaatgga atatgttttt gaattggatg ttcccgggaa    660

agtggaagat gttgtggaga cgttgcttca gcttcacaga gcatcctgcc ttgacaaatt    720

gggtgaccaa accgccatga taacagctat tttgcagtct cgtttagcta gaacatcatt    780

tgacaaaaac aggttccaaa acatttctga aaagctgcac atggaatgca aagcagaaat    840

ggtgacgcct ctggtgacta atcctggaca cgtgtgcatc acggacacaa acctgtattt    900

tcaaccccct cacggctacc cgaaaccctg tggtcagatt acactccaag atgtccgccg    960

catctacaaa aggaggcacg gccctctgcc tctgggcttg gaagnatttt gcaacaaaaa   1020

tgatttgtgg tcccaacttt aactaaagtt tctagaacct caaaaaagag aagaacccta   1080

tttttacatt gccacaaccc aaaaaaacct gggggggaac aacctgctga aaaattattg   1140

gtgaacggac aggaggaaac cttccaatat aaaaactcct ttaccctaaa aaccggggca   1200

aacccatgta aaaacccctc aaaaaccggg gttcccgcga aaaaaatggt gatctccctt   1260

gaaaaacaat tgcaataccc gaaactccct tgttttccaa aactagtgcc ccataaaaac   1320

aggctgtgaa gcactgaacc catcacagtg ctgacaactc tatgtgggac aactcttccg   1380

cgctttacat atcactccta t                                             1401


<210>  171
<211>  948
<212>  DNA
<213>  Homo sapiens

<400>  171
tgagaggatc gcatcaccat caccatcacg gatcctattt aggtgacact atagaatcgt     60

cgacccacgc gtccggcaag gagttgaagc ggctggtgat ggccgagtca gagaagagcc    120

agaagctgga ggagaggctg cgcctgctgc aggcagagac agccagcaac agtgccagag    180

ctgcagaacg cagctctgct ctgcgggagg aggtgcagag cctccgggag gaggctgaga    240

aacagcgggt ggcttcagag aacctgcggc aggagctgac ctcacaggct gagcgtgcgg    300

aggagctggg ccaagaattg aaggcgtggc aggagaagtt cttccagaaa gagcaggccc    360

tctccaccct gcagctcgag cacaccagca cacaggccct ggtgagtgag ctgctgccag    420

ctaagcacct ctgccagcag ctgcaggccg agcaggccgc tgccgagaaa cgccaccgtg    480

aggagctgga gcagagcaag caggccgctg ggggactgcg ggcagagctg ctgcgggccc    540

agcgggagct tggggagctg attcctctgc ggcagaaggt ggcagagcag gagcgaacag    600

ctcagcagct gcgggcagag aaggccagct atgcagagca gctgagcatg ctgaagaagg    660

cgcatggcct gctggcagag gagaaccggg ggctgggtga gcgggccaac cttggccggc    720

agtttctgga agtggagttg gaccaggccc gggagaagta tgtccaagag ttggcagccg    780

tacgtgctga tgctgagacc cgtctggctg aggtgcagcg agaagcacag agcactgccc    840

gggagctgga ggtgatgact gccaagtatg agggtgccaa ggtcaaggtc ctggaggaga    900

ggcagcggtt ccaggaagag aggcagaact cactgcccag gtggaaga                 948


<210>  172
<211>  993
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (892)..(892)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (970)..(971)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (973)..(976)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (981)..(981)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (983)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (986)..(993)
<223>  n is a, c, g, or t

<400>  172
attagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gcgtctcctc aggggggcca gattgcgatc    120

gcgatgaggc ttcggaacca gctccagtca gtgtacaaga tggacccgct acggaacgag    180

gaggaggttc gagtgaagat caaagacttg aatgaacaca ttgtttgctg cctatgcgcc    240

ggctacttcg tggatgccac caccatcaca gagtgtcttc atactttctg caagagttgt    300

attgtgaagt acctccaaac tagcaagtac tgccccatgt gcaacattaa gatccacgag    360

acacagccac tgctcaacct caaactggac cgggtcatgc aggacatcgt gtataagctg    420

gtgcctggct tgcaagacag tgaagagaaa cggattcggg aattctacca gtcccgaggt    480

ttggaccggg tcacccagcc cactggggaa gagccagcac tgagcaacct cggcctcccc    540

ttcagcagct ttgaccactc taaagcccac tactatcgct atgatgagca gttgaacctg    600

tgcctggagc ggctgagttc tggcaaagac aagaataaaa gcgtcctgca gaacaagtat    660

gtccgatgtt ctgttagagc tgaggtacgc catctccgga gggtcctgtg tcaccgcttg    720

atgctaaacc ctcagcatgt gcagctcctt tttgacaatg aagttctccc tgatcacatg    780

acaatgaagc agatatggct ctcccgctgg ttcggcaagc catccccttt gcttttacaa    840

tacagtgtga aagagaagag gaggtagggg ccaagccccc accccatccc antccccttc    900

cctccccaga tatttatgtg aaatgaactg cagctttatt tttttgaaat aaaaaacttt    960

taaaangccn nannnnaaaa nannannnnn nnn                                 993


<210>  173
<211>  1048
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (758)..(758)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (783)..(783)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (819)..(819)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (831)..(831)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (842)..(842)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (892)..(892)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (908)..(908)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (917)..(917)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (945)..(945)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (974)..(974)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (979)..(979)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1003)..(1003)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1010)..(1010)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1022)..(1022)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1027)..(1031)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1034)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1043)..(1048)
<223>  n is a, c, g, or t

<400>  173
agaaattact atgagaggat cgcatcacca tcaccatcac ggatcctatt taggtgacac     60

tatagaatcg tcgacccacg cgtccggccc gctggaaggc tccccgtttc accgtctgct    120

gcacgtgttc gcgtgcgcct gccccggctg tagcaccggc ggtgcgcgca gctggaaggt    180

gttccgctcc cagtgcctgc aggtgccaga gagagaggcg caggacgctc agaaacaggg    240

aaacagcctt gcagctgagg actggtgtga aggtgctgat gactggggaa gtgatactga    300

ggaggggcct tcaccacagt ttaccttgga ttttgggaat gatgccagca gtgccaaaga    360

cgtagactgg actgctcggc tccaagacct ccgcctgcag gatgctgtcc tgggtgctgc    420

ccatcctgtg cctcctgggc tgccgctctt cctgccctac tacatctgtg ttgcagatga    480

ggatgattac agggactttg tcaacctgga tcatgcccac agccttctga gggactatca    540

gcagagagaa ggcattgcca tggatcagtt gctttcccaa agccttccta atgatggtga    600

tgaaaaatat gagaagacca taattaaaag tggagatcag acgttttaca aattcatgaa    660

gcgaattgct gcttgtcagg agcagatttt gaggtattcc tggagtggag agccactctt    720

tttgacctgc cctacatcag aagtcaccga gctcccancc tgcagccagt gtggaggcca    780

aangatattt gagtttcagc ttatgccagc actggtcanc atgctcaaga ntgctaattt    840

angtctttct gtggaatttg gaaacaattc tagtttacac atgtgaaaaa anttgctggc    900

cccccaantc atcaaantcc ccatggaaaa attttgtatt atacnagaaa aacccaaatg    960

aattattgtt taantaaanc antttcnttt tattaaaata aanttaaaan aaatgtttta   1020

cntcccnnnn naannnnnan aannnnnn                                      1048


<210>  174
<211>  1338
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (991)..(991)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1018)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1024)..(1024)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1038)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1056)..(1056)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1090)..(1090)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1125)..(1125)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1173)..(1173)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1193)..(1193)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1197)..(1197)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1209)..(1209)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1216)..(1216)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1221)..(1221)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1225)..(1225)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1228)..(1228)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1242)..(1242)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1251)..(1252)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1258)..(1258)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1260)..(1261)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1276)..(1276)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1279)..(1279)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1281)..(1281)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1287)..(1287)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1293)..(1293)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1303)..(1303)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1309)..(1309)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1311)..(1311)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1328)..(1328)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1334)..(1335)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1337)..(1338)
<223>  n is a, c, g, or t

<400>  174
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg aaagatggcg tcctcggagc aggcagagca    120

gccgagccag ccaagctcta ctccaggaag tgaaaatgtg ctgcctcgag agccgctgat    180

tgccacggca gtgaagtttc tacagaattc ccgggtccgc cagagcccac ttgcaaccag    240

gagagcattc ctaaagaaga aagggctgac agatgaagag attgatatgg ccttccagca    300

gtcgggcact gctgccgatg agccttcgtc cttgggccca gccacacagg tggttcctgt    360

ccagccccct cacctcatat ctcagccata cagtcccgca ggctcccgat ggcgagatta    420

cggcgccctg gccatcatca tggcaggcat tgcatttggc tttcaccagc tctacaagaa    480

atacctgctc cccctcatcc tgggcggccg agaggacaga aagcagctgg agaggatgga    540

ggccggtctc tctgagctga gtggcagcgt ggcccagaca gtgactcagt tacagacgac    600

cctcgcctcc gtccaggagc tgctgattca gcagcagcag aagatccagg agcttgccca    660

cgagctggcc gctgccaagg ccaccacatc caccaactgg atcctggagt cccagaatat    720

caacgaactc aagtccgaaa ttaactcctt gaaagggctt cttttaaatc ggaggcagtt    780

ccctccatcc ccatcagccc cgaagatccc ctcctggcag atcccagtca agtcaccgtc    840

accctccagc cctgcggccg tgaaccacca cagcagcagc gacatctcac ctgtcagcaa    900

cgagtccacg tcgtcctcgc ctgggaagga gggccacagc cccgagggct ccacggtcac    960

ctaccacttg ctgggcccca agaagaaggc naagggggtg gtggacgtca agggccangt   1020

gcgnatggaa gtgcaagncn agaagaaaaa aaggangaca ggaggacaag aggatgagag   1080

gatgatgatn tgaccctgtg nacaagaaga tgcctggggg gcaanggaga ccccggggcg   1140

ggatggcaaa tcacaacagg ggaaaactgg ggncccaggg gcccccaaaa aantaangga   1200

aaagggttnc ccgttncccc ncccnganaa gaataagggg cngggggggc nncccgcncn   1260

ncctgggccg gggggnttnt nccccanggg ggnaaatttc ccncccggng nggggggggg   1320

gggaaaantt tttnngnn                                                 1338


<210>  175
<211>  876
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (602)..(602)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (678)..(679)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (702)..(702)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (744)..(744)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (754)..(755)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (778)..(779)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (781)..(781)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (783)..(783)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (792)..(793)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (799)..(799)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (811)..(811)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (817)..(817)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (819)..(819)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (829)..(829)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (832)..(832)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (841)..(844)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (849)..(849)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (851)..(851)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (858)..(858)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (860)..(860)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (870)..(870)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (876)..(876)
<223>  n is a, c, g, or t

<400>  175
aaaatagaga aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgcccacgc gtccgcccac gcgtccggtg    120

gaggccagca tcctcgcgga gctggccagg cgagcctcgg gacccatttg tctgctgttg    180

gccagcctgc tgtcgctggt ctcagctgtc agtgcctgcc gagtgttcaa gctctggccc    240

ctgtccttcc tcgggagcaa actctccacg tgcgaacagc tccggcaccg gctggagcac    300

ctcacgctaa tcttcagtac acggaaggcg gagaaccctg cccagctgat gaggaaggcc    360

aacacggtgg cctctgtgct gctggacgtg gccctgggcc tcatgctgct gtcctggctc    420

cacgggagaa gccgcatcgg gcatctggcc gacgccctcg ttcctgtggc tgaccacgtg    480

gccgaggagc tccagcatct gctgcagtgg ctgatgggtg ctcccgccgg gctcaagatg    540

aaccgtgcac tggaccaggt gctgggccgc ttcttcctct accacatcca cctgtggatc    600

anctacatcc acctcatgtc ccccttcgtg gagcacatcc tttggcacgt gggcctctcg    660

gcctgcctgg gcctgacnnt ggccctgtcc ctcctctcgg anattatcgc ccctcctcac    720

cttccacatc tactgctttt tacntctatg gaanncaggc tgtaatgcct gaaaaatnna    780

ngncccttgt cnntcattnt gacgtctgtt ncggggnana aaaaattgna ancttttttg    840

nnnnaacgna nggaactncn tgtttcctan tacctn                              876


<210>  176
<211>  1186
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (880)..(880)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (947)..(947)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (959)..(959)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (975)..(975)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (992)..(992)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1023)..(1023)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1028)..(1028)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1038)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1045)..(1045)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1063)..(1063)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1084)..(1084)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1088)..(1088)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1091)..(1091)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1108)..(1108)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1119)..(1119)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1132)..(1132)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1137)..(1137)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1144)..(1145)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1148)..(1148)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1150)..(1150)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1154)..(1154)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1156)..(1156)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1166)..(1166)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1168)..(1168)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1179)..(1179)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1181)..(1182)
<223>  n is a, c, g, or t

<400>  176
naatagagaa attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cgagatccca gtggtagcta ttatggccac    120

tggtggtggg atccgggcaa tgacttccct gtatgggcag ctggctggcc tgaaggagct    180

gggcctcttg gattgcgtct cctacatcac cggggcctcg ggctccacct gggccttggc    240

caacctttat gaggacccag agtggtctca gaaggacctg gcagggccca ctgagttgct    300

gaagacccag gtgaccaaga acaagctggg tgtgctggcc cccagccagc tgcagcggta    360

ccggcaggag ctggccgagc gtgcccgctt gggctaccca agctgcttca ccaacctgtg    420

ggccctcatc aacgaggcgc tgctgcatga tgagccccat gatcacaagc tctcagatca    480

acgggaggcc ctgagtcatg gccagaaccc tctgcccatc tactgtgccc tcaacaccaa    540

agggcagagc ctgaccactt ttgaatttgg ggagtggtgc gagttctctc cctacgaggt    600

cggcttcccc aagtacgggg ccttcatccc ctctgagctc tttggctccg agttctttat    660

ggggcagctg atgaagaggc ttcctgagtc ccgcatctgc ttcttagaag gtatctggag    720

caacctgtat gcagccaacc tccaggacag cttatactgg gcctcagagc ccagccagtt    780

ctgggaccgc tgggtcagga accaggccaa cctggacaag gagcaggtcc cccttctgaa    840

gataaaaaaa ccaccctcaa cagccggcag gatagctgan tttttcaccg atcttctgac    900

gtggcgtcca ctggcccagg ccacacataa tttcctgcgt ggcctcnatt tccacaaana    960

atactttcag catcntcact tttccanatg gnaagctaca ctctggatgg gctccccaac   1020

canctganac cctcggancc ccacntgtgc ctgctggaat gtnggctacc tcataaaaac   1080

aagntgcntg nccttctgga ncccantngg gaagtgganc tctatcctgt antggantaa   1140

aacnnccngn aacntncaaa aattgnanct ctgggccgnt nnccaa                  1186


<210>  177
<211>  1416
<212>  DNA
<213>  Homo sapiens

<400>  177
gcccccccct gagagatact agagaggatg catcaccatc accatcacgg tcgacccacg     60

cgtccgatca gctccacctg cgacatggtg tccgcagcct atgcctccac caaggagagc    120

tacccgcaca tcaagactgt ctgcgacgca gcagagaagg gagtgaggac cctcacggcg    180

gctgctgtca gcggggctca gccgatcctc tccaagctgg agccccagat tgcatcagcc    240

agcgaatacg cccacagggg gctggacaag ttggaggaga acctccccat cctgcagcag    300

cccacggaga aggtcctggc ggacaccaag gagcttgtgt cgtctaaggt gtcgggggcc    360

caagagatgg tgtctagcgc caaggacacg gtggccaccc aattgtcgga ggcggtggac    420

gcgacccgcg gtgctgtgca gagcggcgtg gacaagacaa agtccgtagt gaccggcggc    480

gtccaatcag tcatgggctc ccgcttgggc cagatggtgc tgagtggggt cgacacggtg    540

ctggggaagt cggaggagtg ggcggacaac cacctgcccc ttacggatgc cgaactggcc    600

cgcatcgcca catccctgga tggcttcgac gtcgcgtccg tgcagcagca gcggcaggaa    660

cagagctact tcgtacgtct gggctccctg tcggagaggc tgcggcagca cgcctatgag    720

cactcgctgg gcaagcttcg agccaccaag cagagggcac aggaggctct gctgcagctg    780

tcgcaggccc taagcctgat ggaaactgtc aagcaaggcg ttgatcagaa gctggtggaa    840

gggcaggaga aactgcacca gatgtggctc agctggaacc agaagcagct ccagggcccc    900

gagaaggacc cgcccagcca gagcaggtcg agtcccgggc gctctcccag gtcccgggaa    960

tttgcccccc aatgcaggcc cctggtcctc cctgggtcca acaatccagc ccccccacca   1020

ggtaaagccc cgggccccag cccccccccg tcgaagaccc tctaaccatc ttccgattcc   1080

ctctctctca cctgccccca cattctgccc atatgcacat tttgcccctt ctctcccccc   1140

tcattacctg cgcaatgtgt cccactaccc tgctcatctc gcgacctctc tcccctacct   1200

catacccccc taaacattac cggtctacca cctacacccc ccccccatct aaccctcgca   1260

tctgccccct atcctcttat ccctctctca ccctcgtgcc aataccctcc gtccctccct   1320

tcacaccccc accatacacc attcgcccca ccacagcatc tcactccctc accaactctc   1380

cctaccacgc agcctatccc cacacccaca ccttac                             1416


<210>  178
<211>  1349
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (858)..(858)
<223>  n is a, c, g, or t

<400>  178
ctccccangg ggaacaacct cccaaggaat actcgagagg acgcatcaca tcaccatcac     60

ggtcgaccca cgcgtccggt tcctcgtgcc aacgtgtctt gtaaggtgcg gctagaaact    120

ggggacatgg cagcgcctgg cccagcgctc tgcctcttcg acgtggatgg gaccctcacc    180

gccccgcggc agaaaattac caaagaaatg gatgacttcc tacaaaaatt gaggcagaag    240

atcaaaatcg gagtggtagg cggatcggac tttgagaaag tgcaggagca actgggaaat    300

gatgtggttg aaaaatacga ttatgtgttt ccagaaaatg gcttggtagc atacaaagat    360

gggaaactct tgtgtagaca gaatattcaa agtcatctgg gtgaggccct aatccaagat    420

ttaatcaact actgtctgag ctacattgcg aaaattaaac tcccgaagaa gaggggtact    480

ttcattgaat tccgaaatgg gatgttaaac gtgtccccta ttggaagaag ctgcagccaa    540

gaagaacgca ttgagttcta cgaactcgat aaaaaagaaa atataagaca aaagtttgta    600

gcagatctac ggaaagagtt tgctggaaaa ggcctcacgt tttccatagg aggccagatc    660

agctttgatg tctttcctga tggatgggac aagagatact gtctgcgaca tgtggaaaat    720

gacggttata agaccattta tttctttgga gacaaaacta tgccaggtgg caatgaccat    780

gagatcttca cagaccccag aaccatgggc tactccgtga cagcgcctga ggacacgcgc    840

aggatctgtg aactgctngt ctcctaacgt tggaaccgaa aggggcgggg gtcccggctg    900

acaagccagc atagggcatc cgtggccaga aaccgaaggc cccccacacg tgctcacccc    960

ccgcagccta agcaagctct gcatgcttag ccaggcaggg gcaaacctgg atttcccccc   1020

ccaggcccaa aatttccaaa aggaaagaaa aacctccgtc caaaagggcc caaaagaagg   1080

gccccccaaa aaggtttccc cccccccccc cccccccaaa taaaaacccc ccctaaaacg   1140

ggcaacattg gaattttgcc ccaatatccc cacctctccg tatagaacca aaaaaaaatg   1200

ggcccggcac cccccctccg aggggctccg caaaaaaaac gcattattaa aggcaccccc   1260

acaaacaaca aatggcgatt gcaaataaac aaccaccccc tccctcgcga ctcctctccc   1320

acatagagct accaaccccc ctaccacac                                     1349


<210>  179
<211>  1114
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (5)..(5)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (912)..(912)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (918)..(918)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (947)..(947)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (955)..(955)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (957)..(957)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (970)..(971)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (974)..(975)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (978)..(978)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (998)..(998)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1034)..(1034)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1044)..(1044)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1058)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1080)..(1080)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1095)..(1097)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1102)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1108)..(1108)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<400>  179
naatngagaa aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgcgagcaa gatggccacc accaagcgcg    120

tcttgtacgt gggtggactg gcagaggaag tggacgacaa agttcttcat gctgcgttca    180

ttccttttgg agacatcaca gatattcaga ttcctctgga ttatgaaaca gaaaagcacc    240

gaggatttgc ttttgttgaa tttgagttgg cagaggatgc tgcagcagct atcgacaaca    300

tgaatgaatc tgagcttttt ggacgtacaa ttcgtgtcaa tttggccaaa ccaatgagaa    360

ttaaggaagg ctcttccagg ccagtttggt cagatgatga ctggttgaag aagttttctg    420

ggaagacgct tgaagagaat aaagaggaag aagggtcaga gcctcccaaa gcagagaccc    480

aggagggaga gcccattgct aaaaaggccc gctcaaatcc tcaggtgtac atggacatca    540

agattgggaa caagccggct ggccgcatcc agatgctcct gcgttctgat gtcgtgccca    600

tgacagcaga gaatttccgc tgcctgtgca ctcatgaaaa gggctttggc tttaagggaa    660

gcagcttcca ccgcatcatc ccccagttca tgtgccaggg cggtgatttc acaaaccaca    720

atggcactgg gggcaagtcc atctatggga agaagttcga tgatgaaaac tttatcctca    780

agcatacggg accaggtcta ctatccatgg ccaactctgg cccaaacacc aatggctctc    840

agttcttcct gacatgtgac aagacagact ggctggatgg caagcatgtg gtgtttggag    900

aggtcaccga angcctanat gtcttgcggc aaatttgaga aaacagnaag agtcnancaa    960

ttaccacccn nccnnagntc ctggaanctg acgtaaanct cgtgccgacg gcaaaacctg   1020

ccggccgtgg gaanccgtgg aacntcctct gcaggganna aaagggccan ggtctttttn   1080

tgggggttcc cactnnnggg cncctacntn tggg                               1114


<210>  180
<211>  934
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (847)..(847)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (883)..(883)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (890)..(890)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (892)..(892)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (895)..(896)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (907)..(913)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (920)..(920)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (924)..(924)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (927)..(927)
<223>  n is a, c, g, or t

<400>  180
taagagaaat tactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg ggaggagaaa gatggcggct accttactag    120

ctgctcgggg agccgggcca gcaccggctt gggggccgga ggcgttcact ccagactggg    180

aaagccgaga agtttccact gggaccacta tcatggccgt gcagtttgac gggggcgtgg    240

ttctgggggc ggactccaga acaaccactg ggtcctacat cgccaatcga gtgactgaca    300

agctgacacc tattcacgac cgcattttct gctgtcgctc aggctcagct gctgataccc    360

aggcagtagc tgatgctgtc acctaccagc tcggtttcca cagcattgaa ctgaatgagc    420

ctccactggt ccacacagca gccagcctct ttaaggagat gtgttaccga taccgggaag    480

acctgatggc gggaatcatc atcgcaggct gggaccctca agaaggaggg caggtgtact    540

cagtgcctat ggggggtatg atggtaaggc agtcctttgc cattggaggc tccgggagct    600

cctacatcta tggctatgtt gatgctacct accgggaagg catgaccaag gaagagtgtc    660

tgcaattcac tgccaatgct ctcgctttgg ccatggagcg ggatggctcc agtggaggag    720

tgatccgcct ggcagccatt gcagagtcag gggtagagcg gcaagtactt ttgggagacc    780

agatacccaa attcgccgtt gccactttac cacccgcctg aatcctggga ttctagtatg    840

caataanaga tgcccctgta ctgatgcaaa atttaataaa agntttgtcn cngannaaaa    900

aaaaaannnn nnnaaaaaan gggnggnccg ctcc                                934


<210>  181
<211>  1216
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (808)..(808)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (847)..(847)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (850)..(850)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (909)..(909)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (921)..(921)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (936)..(936)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (963)..(963)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (965)..(965)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (983)..(983)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (990)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (993)..(993)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (998)..(998)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1011)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1018)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1024)..(1025)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1029)..(1029)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1032)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1051)..(1051)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1057)..(1057)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1076)..(1076)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1078)..(1078)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1119)..(1119)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1127)..(1127)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1129)..(1130)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1135)..(1135)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1148)..(1148)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1160)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1164)..(1164)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1186)..(1186)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1191)..(1192)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1202)..(1202)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1210)..(1210)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1214)..(1214)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1216)..(1216)
<223>  n is a, c, g, or t

<400>  181
atagagaaat tactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg ccatgtcctt gaagcttcag gcaagcaatg    120

taaccaacaa gaatgacccc aagtccatca actctcgagt cttcattgga aacctcaaca    180

cagctctggt gaagaaatca gatgtggaga ccatcttctc taagtatggc cgtgtggccg    240

gctgttctgt gcacaagggc tatgcctttg ttcagtactc caatgagcgc catgcccggg    300

cagctgtgct gggagagaat gggcgggtgc tggccgggca gaccctggac atcaacatgg    360

ctggagagcc taagcctgac agacccaagg ggctaaagag agcagcatct gccatataca    420

gtggctacat ctttgactat gattactacc gggacgactt ctacgacagg ctcttcgact    480

accggggccg tctgtcgccc gtgccagtgc ccagggcggt ccctgtgaag cgaccccggg    540

tcacagtccc tttggtccgg cgtgtcaaaa ctaacgtacc tgtcaagctc tttgcccgct    600

ccacagctgt caccaccagc tcagccaaga tcaagttaaa gagcagtgag ctgcaggcca    660

tcaagacgga gctgacacag atcaagtcca atatcgatgc cctgctgagc cgcttggagc    720

agatcgctgc ggagcaaaag gccaatccag atggcaagaa gaagggtgat ggaggtggcg    780

ccggcggcgg cggcggtggt ggtggcancg gtggcggtgg cagtggtggt ggcggtggcg    840

gtggcancan ccggccacca gccccccaag agaacacaac ttctgaggca ggcctgcccc    900

agggggaanc acggacccga nacgacggcg atgagnaaag gctcctgaca cacagcgagg    960

aananctgga acacagccag ganacaaacn cgnatgangg ggccnttgca ntaancancc   1020

tganngganc antggccacn accaggtgaa nggcatngnt tgccccaggc ctcaancngg   1080

gcaccaaccc tggatgcccc ccccancggg taccaaaana aactggnann agggncctcc   1140

tccccaanga atccaaccan ggcnatgttc tttgcagggg aattangggc nnattcttcc   1200

cnagaacccn cctntn                                                   1216


<210>  182
<211>  939
<212>  DNA
<213>  Homo sapiens

<400>  182
tatgagaggt cgcatcacca tcaccatcac ggatcctatt taggtgacac tatagaatcg     60

tcgacccacg cgtccggttc taagagggac atggcctcca atgaaggcag tcgcatcagt    120

gctgcctctg tggccagcac tgccattgct gcggcccagt gggccatctc acaggcctcc    180

caaggtgggg agggtacctg ggccacctcc gaggagccgc cggtcgacta cagctactac    240

caacaggatg agggctatgg caacagccag ggcacagagt cttccctcta tgcccatggc    300

tacctcaagg gcaccaaggg ccctggcatc actggaacca aaggggatcc cactggagca    360

ggtcccgagg cctccctaga gcctggggcc gactctgtgt cgatgcaggc tttctctcgc    420

gcccagcctg gtgctgctcc tggcatctac caacaatcag ccgaggcgag cagtagccag    480

ggcactgctg ccaacagcca gtcgtatacc atcatgtcac ccgctgtgct caaatctgag    540

ctccagagcc ctacccatcc tagttctgct ctcccaccgg ctaccagccc cactgcccag    600

gaatcctaca gccagtaccc tgttcccgac gtctctacct accagtacga tgagacctcc    660

ggctactact atgaccccca gaccggcctc tactatgacc ccaactccca gtattactac    720

aatgctcaga gccagcagta cctgtactgg gatggggaga ggcggaccta tgttcccgcc    780

ctggagcagt cggccgacgg acataaggag acaggggcac cctcgaagga gggcaaagag    840

aagaaggaga agcacaagac caagacagct caacagattg ccaaggacat ggaacgctgg    900

gcccgcagtc tcaacaaaca aaaagaaaac ttcaaaaat                           939


<210>  183
<211>  1041
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (668)..(668)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (698)..(698)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (723)..(723)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (725)..(725)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (766)..(766)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (842)..(842)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (844)..(844)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (853)..(853)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (877)..(877)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (893)..(893)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (898)..(898)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (903)..(903)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (907)..(907)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (914)..(914)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (922)..(922)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (925)..(925)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (930)..(931)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (933)..(933)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (940)..(940)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (944)..(944)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (947)..(948)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (953)..(953)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (955)..(955)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (958)..(958)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (969)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (972)..(972)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (983)..(983)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1003)..(1003)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1016)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1028)..(1028)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1031)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1034)..(1034)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<400>  183
tagagagatt aactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg acgccaccaa gagtcaagtg tttgaccacg    120

agaccaaggg cagcgtggcc gtgcgcgtgg ctctggggga aacccagctc gtccaggaag    180

tgcggcgttt tctcatagac aacggggtca gcctggattc cttcagccag gctgcagcag    240

agcgaagcaa gactgtgatt ctggtcaaga acctcccggc aggcaccctg gcggccgagc    300

tgcaggagac cttcggccat tttggcagcc tgggccgcgt gctgctgcca gagggcggaa    360

tcactgccat cgtggagttc ctggagcccc tggaggcccg caaggccttc aggcatctgg    420

cctattccaa gttccatcat gtccccctct atctggagtg ggctccagtt ggcgtcttct    480

ccagcacagc cccacagaag aaaaagctcc aagacacacc ttcagaaccc atggaaaagg    540

acccagcaga gccagaaaca gtgcctgatg gcgaaacccc agaagatgaa aatccaacag    600

aggaaggagc agacaactct tcagcaaaga tggaagagga ggaggaggaa gaggaagaag    660

aagaaganag cctcccagga tgtactctgt ttattaanaa tctcaatttt gacacaacag    720

aananaagct gaaggaagtg ttttcaaaag tggggacagt gaaaanctgc tccatctcca    780

agaaaaaaaa acaaagcagg agtgctcctt tccatggggg tttggatttt gtgggaatac    840

angnaagccg gancaagccc aaaaagctct caagcanctc cagggtcacg tcntggangg    900

ccncaanctg gaantgagga tntcngaacn nanccctaan ccanccnnga aantngcntc    960

gaaaaaaana anttcccaaa aanaaancac cctccaaaaa tcntgggggg aaaaancccc   1020

ttccaggncc naanccgggn a                                             1041


<210>  184
<211>  877
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (790)..(790)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (807)..(807)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (839)..(839)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (853)..(853)
<223>  n is a, c, g, or t

<400>  184
gagagatact atgagaggac gcatcaccat caccatcacg gatcctattt aggtgacact     60

atagaatcgt cgactctgga ccttggctgt cactcagtta aggcctattt ccaaaccgac    120

cgaccagcag agcagttcca cctccagaat aatgcaccag gaaactgtga ccatcctcta    180

ccagagacaa cagctactgg ggatcctacc cattccaaca caactgaatc tggggagcaa    240

catcaccaag tagacttaac agggaatcag ccacatcaag catatttatc tggggaccca    300

gaaaaggcca gaattacttc agttccctta gactcagaga agtctgatga tcatgtaagt    360

ttccctgaag accagtctgg gaagaacagt atgccaactg tctccttctt ggatcaggac    420

cagtctccac cccgtttcta cagtggagat cagcctcctt cttatcttgg tgcaagtgtg    480

gataaactcc atcacccttt agaatttgca gacaaatctc ccacacctcc taatttacct    540

agcgataaaa tctaccctcc ttctgggtcc cccgaagaga ataccagcac agccaccatg    600

acttacatga caactactcc agcaacagcc caaatgagca ccaaggaagc cagctgggat    660

gtggctgaac aacccaccac tgctgatttt gctgctgcca cacttcagcg cacgcacaga    720

actaatcgtc cccttccccc tccgccttcc agagatctgc agagcagccc cacagtgtgg    780

ggcaggtacn agcagcaacc catatangga ttaataattc ccccaggttc aaggagtant    840

tcagtttcag aanagcactg acctcgagca tgatgac                             877


<210>  185
<211>  1410
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (713)..(714)
<223>  n is a, c, g, or t

<400>  185
nggcaaaata cttccaagaa ttactagaga ggatcgcatc accatcacca tcacggtcga     60

cccacgcgtc cgactggaga aaacattgat acttccagtg accttatgct ggctcagatg    120

ctacagatgg aatatgacag agaatatgat gcacagctta ggcgtgaaga aaaaaaattc    180

aatggagata gcaaagtttc catttccttt gaaaattatc gaaaagtgca tccttatgaa    240

gacagcgata gctctgaaga tgaggttgac tggcaggata ctcgtgatga tccctacaga    300

ccagcaaaac cggttcccac tcctaaaaag ggctttattg gaaaaggaaa agatatcacc    360

accaaacatg atgaagtagt atgtgggaga aagaacacag caagaatgga aaattttgca    420

cctgagtttc aggtaggaga tggaattgga atggatttaa aactatcaaa ccatgttttc    480

aatgctttaa aacaacatgc ctactcagaa gaacgtcgaa gtgcccgcct acatgagaaa    540

aaggagcatt ctacagcaga aaaagcagtt gatcctaaga cacgtttact tatgtataaa    600

atggtcaact ctggaatgtt ggagacaatc actggctgta ttagtacagg aaaggagtct    660

gttgtctttc atgcatatgg agggagcatg gaggatgaaa aggaagatag tannagtata    720

cctacagaat gtgccatcaa ggtattttaa acaaccctta atgaattaag aatcgtgaca    780

aatatattaa agatgatttc aggtttaaag atcgcttccg aaaactaatc cacgttaaat    840

catcccgcat ggggggcaaa aaaaaaatgc ccattcccca aaaatgcgaa aaactgggaa    900

tccttggccc accgttggac caatgaaaaa accactttaa gttaaggcct ttatgggccc    960

ggaccaatcc cccaccccca aattaaaaaa agtaagcctc caaagtgcaa aaatgaaaaa   1020

acccccttaa cctccttttt ttatccccga ttatctctaa agggccacct ccccagctcc   1080

acaccaaaaa aacacaccac gcctaaccaa aaacaccaga cacacactaa ccaccaacaa   1140

acaccaccca cccacaccca cattacacta accacccacc acccatccta ctctttaact   1200

aaacaccacc acacccatcc ctcgcctcac ccgtccacaa caccccccct cacacagaca   1260

catcctacca caacaccacc aataatacac cgtctaccct accaccctca cacacttcct   1320

ccccactcac aacactactc caatcaacaa ccaccacacc aaacacaaca agctcccacc   1380

tccaaccaaa ccaccgctca cacaacctca                                    1410


<210>  186
<211>  1408
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (605)..(606)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (608)..(609)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (611)..(613)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (615)..(618)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (623)..(623)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (626)..(626)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (628)..(628)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (644)..(644)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (681)..(681)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (782)..(782)
<223>  n is a, c, g, or t

<400>  186
cgcncttaag agatactaga gaggatgcat cccatcacca tcacggtcga cccacgcgtc     60

cggctcccgc tgctgctgct ctggactcgg gggactcagg ggtccgagct ggaccccaaa    120

gggcagcacg tctgtgtggc cagcagcccc tctgctgagc tgcagtgctg cgcaggctgg    180

aggcagaagg atcaagaatg caccatcccc atctgtgagg ggccggacgc ctgccagaaa    240

gacgaggtgt gtgtgaagcc gggcctctgt cgatgcaagc ctggattctt tggggcccac    300

tgcagctccc gctgcccggg ccagtactgg ggccccgact gccgtgagag ctgcccctgc    360

cacccgcacg gccagtgcga gccagccacg ggcgcgtgcc agtgccaggc cgaccgctgg    420

ggagcccgct gcgagttccc gtgcgcctgc ggcccccacg ggcgctgcga ccccgcgacc    480

ggcgtgtgcc actgcgaacc cggctggtgg tcgtccacgt gccgccgccc gtgccagtgc    540

aacaccgcgg cggcgcgctg cgagcaggcc acgggcgcct gcgtgtgcaa gccgccctgg    600

tgggnncnnc nnngnnnntt ccnctncnct gccccccctc cccntgccag catggttccc    660

gcccctgtcc ctgccgctcg nttgcccgct tccgcacacg ccccaaaacc ggcacattgc    720

tatcctgatt ataaccaacc cctacatcca caacactctt cctcccgctc cccccatcct    780

tnaaaaaaag ttatattata cctcttattt taatttaata tccacgccaa ctcttatacc    840

cacaaaacac cccactaccc attcccccac catcaacccc aaacaccact tcccctaaca    900

ctatccccta cactccacat gacctccccc tcaaatacac ccactctttc caaactcaca    960

tcacactcca tactcaaacc cactcactaa ttcttccccc ccaccattct cacccaaatc   1020

tcaacaccct cacatcaccc ttccttactc accccctcta ccatccatcc cacccctatc   1080

acccctctca caccaacacc cccaccctct acacccccca ctccctctcc ctctctccac   1140

cacccccttc acactccaca caccacccac actcgctctc ctctcacctc actcctcccc   1200

ccattccgcc gcctcccctc ctctcccaca ccctcccctc ttctttcttc actccacttt   1260

ccccccactt acacactatc aaaatacact cacctacatc atcccacacc ccaccacttc   1320

cactctctcc cccacaccca cacctacaat cacctctcca tacctcatcc catctcccac   1380

taatctcgct ccctttacct tcccctca                                      1408


<210>  187
<211>  1083
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (855)..(855)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (860)..(860)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (878)..(878)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (913)..(913)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (928)..(928)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (930)..(930)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (940)..(940)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (951)..(951)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(957)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (960)..(960)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (962)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (980)..(980)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (990)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (996)..(996)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (999)..(999)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1009)..(1009)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1018)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1021)..(1021)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1026)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1043)..(1043)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1053)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1067)..(1067)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1072)..(1072)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1075)..(1075)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1080)..(1080)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1083)..(1083)
<223>  n is a, c, g, or t

<400>  187
ntanttagag aaattactat gagaggatcg catcaccatc accatcacgg atcctattta     60

ggtgacacta tagaatcgtc gacccacgcg tccgtgctgc gggaggcggc agaggctggg    120

gccgaagcga ggctcgccct ggacggggag acgctgggcg aggaggaaca ggaggatgag    180

cagccaccct gggccagccc gagccccacc tcaaggcaga gcccggcgtc ccccccgccc    240

ctgggaggtg gcgccccggt gcggacggcc aaagctgaac ggcgccacca ggagcggctg    300

cgcgtgcaga gtccggagcc accggcaccc gagcgtgccc tgtcccctgc cgagctccgg    360

gccctggagg ccgagaagcg tgcgctgtgg agggcagcca ggatgaagtc attggaacag    420

gacgctctcc gagcacagat ggtcctcagc aggtcccagg aaggccgggg cacgcggggg    480

cccctggagc gactggccga ggccccttcc cctgcgccca ccccgtcgcc cacccctgtg    540

gaagacctcg gcccccagac cagcacctcc ccgggacgcc tgcccttgtc tggaaagaag    600

tttgactaca gggcctttgc ggccctgcct tcttccagac ctgtctatga catccagtca    660

ccggactttg ctgaggagtt gaggtccctg gaaccatctc ccagccctgg cccgcaggag    720

gaggatggag aagtggctct ggtgcttctg ggcaggccct cacccggcgc tgtgggccct    780

gaagatgtgg cactgtgcag cagccgccgc cccgtaaggc ctgggcgccg tggcctgggc    840

cctgtgccct cctanaggan caggcacctc ccccagantt ggggtggggg ccctgccagc    900

tccagcacca ccnttgccca agtctttnan ctgggtgtan cattttaaaa nacccnnagn    960

anttttggcc tgtgactaan taantgcccn acccanccna aactnggcna aatgtaanta   1020

ntgatntttt acaaccaaaa atnttttttt tgnttaagna aaaaaanttn antanttttn   1080

ctn                                                                 1083


<210>  188
<211>  759
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (17)..(17)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (22)..(22)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (25)..(25)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (67)..(67)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (81)..(81)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (91)..(91)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (116)..(116)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (184)..(184)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (229)..(229)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (245)..(245)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (282)..(282)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (294)..(294)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (337)..(337)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (343)..(343)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (364)..(364)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (371)..(371)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (391)..(391)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (396)..(396)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (415)..(416)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (419)..(419)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (423)..(424)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (427)..(427)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (429)..(429)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (450)..(450)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (455)..(455)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (485)..(485)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (506)..(508)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (514)..(514)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (516)..(516)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (532)..(532)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (543)..(543)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (550)..(550)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (563)..(563)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (584)..(584)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (586)..(586)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (589)..(589)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (593)..(593)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (604)..(604)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (614)..(614)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (621)..(622)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (633)..(634)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (640)..(640)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (658)..(659)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (661)..(661)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (668)..(668)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (678)..(678)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (682)..(682)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (695)..(695)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (699)..(699)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (701)..(701)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (707)..(707)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (726)..(726)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (731)..(731)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (745)..(745)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (750)..(750)
<223>  n is a, c, g, or t

<400>  188
aanaaantag agaaaantta cntangagag gatcgcatca ccatcaccat cacggtatcc     60

tatttangat gacacttatt nttaatcgtc nacccacgtc gtccgggcgg cgtccncggt    120

ttcgcaggtc tttcgctgag cgtctctgct tagccgcggt catgagccgg cacagtccgg    180

ctgnagaggc aggttctgag cctgtaccgc gatctgctgc gcgccgggng tgggaagccg    240

ggcgncgagg cgcgagtgcg ggcagagttc cggcagcatg cnggcctgcc gcgntccgac    300

gtgctgcgca tcgagtacct gtaccgccgc gggcggngcc agntgcagct gctacgctcg    360

ggcnacgcca ncgccatggg cgccttcgta ngcccncggg ccccgaccgg ggagnntgnc    420

ggnntgngnt cccagcctga cgacggctan agtcnaagga acccccacaa cagttacggg    480

ggcancggag acccggcccg actgannnag acangnaaat agccaaaact cnctcgatgg    540

canggtggan ccaggaagct cgnctgactg catgggggga ctgngnaanc cancctaagg    600

tganagatct taanaaacta nnttgacgaa ttnnggatgn catagactcc tccttggnna    660

ngcaaggngc ctacagancc cnttgatgga ctgcnaggna ngccccncct ttttcgatgc    720

ttgganactg ntctgtgctc ctccnccatn atggcttag                           759


<210>  189
<211>  0
<212>  DNA
<213>  Homo sapiens

<400>  189
<210>  190
<211>  880
<212>  DNA
<213>  Homo sapiens

<400>  190
cattgagaga tactatgaga ggatgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgactc tggaccttgg ctgtcactca gtttatggcc taggcatggc    120

tcagccagca gccccctccc tgacgcggcc cttcctggca gaggccccga cagcactggt    180

cccacacagc cccctgcctg gggccctgtc aagcgcccct ggcccgaagc agcccccgac    240

ggcaagcaca ggcccggagc tgctgctgct gcctccttcc tccttcatgc cctgcggggc    300

ggctgcacca gccggggtgt cagcacagcg ggctactcct agggataagc ccccggtccc    360

ctcatccctg gccagtgtcc ctgaccccca tctactcctt cctggggact tctcagccac    420

cagggctggg cctggacttt caactgcagg cagcctggac cttgaggctg aacttgagga    480

gatccagcat caactactgc actaccagac caccaagcag aacctctggt cctgtcggcg    540

gcaagcgagc agcctgcgca ggtggctgga gctgaacaga gaggagccag ggcctgagga    600

ccaggaagta gagcaccacg tgcagaaaga gcaggaacag gtggaaatgc atatccacct    660

gctggcaaag gagctccagg ctcagcgcca gcccattggc gcctgcgtta gccgcaatct    720

ggccctgcag caggctctgt gctagcgtgt tcgcaccaga aaagcaagtg ctgggctgtc    780

agggaagctc aagctactcc cggaacaaac caagatttag tttgattttt atattcaaaa    840

tctttgcaat tagtgagtac tgttcaaaaa aaattaaaaa                          880


<210>  191
<211>  468
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (8)..(9)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (20)..(20)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (24)..(24)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (27)..(27)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (29)..(29)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (31)..(31)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (36)..(36)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (42)..(42)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (54)..(54)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (83)..(83)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (280)..(280)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (286)..(286)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (325)..(326)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (342)..(342)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (398)..(398)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (404)..(405)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (412)..(412)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (433)..(433)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (440)..(440)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (443)..(443)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (451)..(451)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (467)..(467)
<223>  n is a, c, g, or t

<400>  191
aaanangnnt naaaaaaacn aatnctntng ngcagnagta tnttaactat gagnaggatc     60

gcatcaccat acaccatcac ggnatcctat ttaggtgaca ctatagaatc gtcgacccac    120

gcgtccgctg gagagaaaac ttacacacag cgatgtcggt tgtttgttgg gaatctacct    180

gctgatatca cggaggatga attcaaaaga ctatttgcta aatatggaga accaggagaa    240

gtttttatca acaaaggcaa aggattcgga tttattaagn tttttntaga gctttggctg    300

aaattgccaa agccgaactg ggtgnnacac ccatgagagg cnccacagct tcgagttcgc    360

tttgccacac atgctgctgc cctttctgtt cgtaaaanaa aaanntatgt tnccaatgaa    420

ctgttggaag aancctttan ccnatttggt nctattgaaa gggctgnt                 468


<210>  192
<211>  895
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (792)..(792)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (836)..(837)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (839)..(840)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (844)..(846)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (848)..(851)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (853)..(856)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (858)..(862)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (866)..(866)
<223>  n is a, c, g, or t

<400>  192
tagagagaat tactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg gtgcagctgc cgctaccgcc gccctctgcc    120

cgccggcccg tctgtctacc cccagcatga gcggcctgcg cgtctacagc acgtcggtca    180

ccggctcccg cgaaatcaag tcccagcaga gcgaggtgac ccgaatcctg gatgggaagc    240

gcatccaata ccagctagtg gacatctccc aggacaacgc cctgagggat gagatgcgag    300

ccttggcagg caaccccaag gccaccccac cccagattgt caacggggac cagtactgtg    360

gggactatga gctcttcgtg gaggctgtgg aacaaaacac gctgcaggag ttcctgaagc    420

tggcttgagt caagcctgtc cagagttccc ctgctggact ccatcaccac actcccccca    480

gccttcacct ggccatgaag gaccttttga ccaactccct gtcattccta acctaacctt    540

agagtccctc ccccaatgca ggccacttct cctccctcct ctctaaatgt agtcccctct    600

cctccatcta aaggcaacat tccttaccca ttagtctcag aaattgtctt aagcaacagc    660

cccaaatgct ggctgccccc agccaagcat tggggccgcc atcctgcctg gcactggctg    720

atgggcacct ctgttggttc catcagccag agctctgcca aaggccccgc agtccctctc    780

ccaggaggac cntaaaaggc aattaaatga tgtcctgttc cattggaaaa aaaaannann    840

aaannnannn nannnnannn nngggncggc cgctccctta taaggagtcc gtatt         895


<210>  193
<211>  1023
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (836)..(836)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (838)..(838)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (843)..(843)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (864)..(864)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (871)..(871)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (874)..(874)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (878)..(878)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (880)..(880)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (921)..(921)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (930)..(930)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (943)..(943)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (973)..(974)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (981)..(981)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1002)..(1002)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1008)..(1008)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1012)..(1013)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1021)..(1021)
<223>  n is a, c, g, or t

<400>  193
nttagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gcccagcaac acgctcctga cttcccttcc    120

caaggactcg acctgagaac cgccatgtac tcggagatcc agagggagcg ggcagacatt    180

gggggcctga tggcccggcc agaatacaga gagtggaatc cggagctcat caagcccaag    240

aagctgctga accccgtgaa ggcctctcgg agtcaccagg agctccaccg ggagctgctc    300

atgaaccaca gaaggggcct tggtgtggac agcaagccag agctgcagcg tgtcctagag    360

caccgccggc ggaaccagct catcaagaag aagaaggagg agctggaagc caagcggctg    420

cagtgcccct ttgagcagga gctgctgaga cggcagcaga ggctgaacca gctggaaaaa    480

ccaccagaga aggaagagga tcacgccccc gagtttatta aagtcaggga aaacctgcgg    540

agaattgcca cactgaccag cgaagagaga gagctgtagg gccagctgcc gggctcaggc    600

cactgcccac cctggcctgg acagcctcct tcagcccttc tgtacctggc agccctgggc    660

cccaggccct gggacgtctg tgatgttccc acctgcttct gtagaaatgt gtcaccccag    720

agggcctggc tctccctggg aggctggggc ccctaagctc ctaggttttc cttccaagca    780

cccagccctc ctgctccaag agggataacc tgcacccctc cctgcaaggg gttcanancc    840

cancacagga gctttctctg gcanaattga ngangaanan gtggccctct gacttgacaa    900

gccttctgtt ctgcccaggc nttccaccan gaatctccga ggntcccagg gcccgcttct    960

ccgtanaccc canntcntag ntctcaaaaa ctccccncct gnggtttnct gnnccnnnaa   1020

ntt                                                                 1023


<210>  194
<211>  828
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (749)..(749)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (751)..(751)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (762)..(762)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (785)..(785)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (796)..(796)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (804)..(804)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (812)..(812)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (821)..(822)
<223>  n is a, c, g, or t

<400>  194
tnaactatga gaggatcgca tcaccatcac catcacggat cctatttagg tgacactata     60

gaatcgtcga cccacgcgtc cgacagcttg gagagagcag gatccaagca gtacagtgca    120

gccattgcct tcaccctggc cctcttttcc cacctcgtca atcatgtcaa catacggctg    180

caggctgagc tggaagaggg cgagaatccc gtcccggcat tccagagtga tggcacagat    240

gaaccagagt ccaaggaacc tgtggagaaa gaggaggagc cagatcctga gcctcctcct    300

gtaacacccc aagtgggtga gggcagaaag agccgtaagt tctctcgcct ctcctgtctc    360

cgccgtcgcc gccacccacc caaagttggt gatgacagtg acctgagtga aggctttgaa    420

tcggactcaa gccatgactc agcccgggcc agtgagggct cagacagtgg ctctgacaag    480

agtcttgaag gtgggggaac ggcctttgat gctgaaacag actcggaaat gaatagccag    540

gagtcccgat cagacttgga agatatggag gaagaggagg ggacacgggt caccaaccct    600

gggagccccc tcggggcaga tcagaggctc ccgattccct caatggccca ctgggcccca    660

gtgaggctag cattgccagc aatctacaag ccatgtccac ccaagatgtt ccagactaag    720

cgctgcttcc cgactggccc ccacctttna naacctgttt cntccagccc aaccaccaaa    780

ccctnatacc ttcggncagc ccanaggcct tngcgttcaa nnggggaa                 828


<210>  195
<211>  1338
<212>  DNA
<213>  Homo sapiens

<400>  195
ccatatactg acttacctat aaataggcgt atcacgaggc cctttcgtct tcacctcgag     60

aaatcataaa aaatttattt gctttgtgag cggataacaa ttataataga ttcaattgtg    120

agcggataac aatttcacac agaattcatt aaagaggaga aattaactat gagaggatcg    180

catcaccatc accatcacgg tcgacccacg cgtccgcggc cgccgggagt cgggaccgcc    240

agtcggggcg ccgggaccat ggcgctgcgc gcccgggcgc tgtacgactt caggtcggag    300

aacccaggag agatctcgct gcgagagcac gaggtgctga gcctgtgcag cgagcaggac    360

atcgagggct ggctcgaggg ggtcaacagc cgcggcgacc gcggcctctt cccggcctcc    420

tatgtgcagg tgatccgcgc ccccgagcct ggcccggcgg gagacggcgg cccgggcgcc    480

ccggcccgct acgccaatgt gccccccggg ggatcccacc ccccgacccg gccgcccccc    540

accgcgttca tcccccaccc caaaccctcc atctacatgc cgagcccacg acccccacca    600

catctccaac ccatacaacg ctcccaacaa cacctcacac cacccctaca cccctcaaca    660

ttcccccccc tatcacccca ctcttccata tacttcccca caaccgacca tcactacaca    720

caacaaacat acacctccac cctcatctac acaaccgcca cccacatccg ttactcctca    780

ccattcccca caccatgcac ctcactacat acagcaacca tcttccaagc aatcctactc    840

ctacaccaca cttccgcgat ccacacgaat acaccccgca aaccccctgc aatccaacca    900

cacccgatcc acccacacac acatccacat ctctacccct ctatacaaca ctcacaccac    960

aaacaccaca caacttaaca cactcctcct caacacccca cgcattacca ccaccactac   1020

acactctatc acacaacata tcgcccaaca cactaaacac acacaactca ccccccccat   1080

tttttggttg ccctgctccc atccatacct aaccaacaca catatccaac acacaccacc   1140

atacctaaac cttccgtaca aacaccctcc aaccactcca tatacccctc aaaaccctaa   1200

cacatcaccc acattaaaca atatcctact atcaccacaa ctgacacaca ctacacatac   1260

caccacctat tcataatgca aaaggcacac aaccaccaca ccgccataca gacgacctct   1320

ccattactcg cacagcag                                                 1338


<210>  196
<211>  497
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (373)..(373)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (379)..(380)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (382)..(382)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (385)..(385)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (391)..(391)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (404)..(404)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (406)..(407)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (414)..(414)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (416)..(416)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (438)..(438)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (440)..(440)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (455)..(455)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (460)..(460)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (463)..(463)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (466)..(466)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (469)..(469)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (477)..(477)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (487)..(487)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (489)..(489)
<223>  n is a, c, g, or t

<400>  196
taagaggaga attaactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgagatcct ggaggagatc aagcaggagc    120

ggaggctgcg cccggtgcgg ggcgagggct gggctgcccg cgggtttggc tctctgccct    180

gcatcctcaa cgcctgctcc ggagatgcca agtccacctc ctgcatcaac ctgtcagtca    240

cagatgctgg gggcagcgcc cagcgcccgc ggccccgcgt gctgctcaag gcgcctacct    300

tggctgaaat ggaagagatg aatacatctg aggaagaaga gtctccgtgt ggggaggtga    360

cgctgaaaag ggnaccgcnn cnttntcaaa naatgacctg gccnanntcc gaangngggg    420

gccttttggc ctgaaatngn cccccacccc ccggngggan ggnccnccnc gcccccnaat    480

tggaaangnc atttggg                                                   497


<210>  197
<211>  1388
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (8)..(12)
<223>  n is a, c, g, or t

<400>  197
gcagaaannn nnggatatac tgacttacct ataaataggc gtatcacgag gccctttcgt     60

cttcacctcg agaaatcata aaaaatttat ttgctttgtg agcggataac aattataata    120

gattcaattg tgagcggata acaatttcac acagaattca ttaaagagga gaaattaact    180

atgagaggat cgcatcacca tcaccatcac ggtcgaccca cgcgtccgga agtctctaca    240

ccattcccac ctcttccgcc agaacctgag ggtggtgggg aggagaaggt tgtaggcatg    300

gaagagagcc aggcagcccc gaaagaagag cctgggccac ggccacgtat aaacctccga    360

ggggtcatga ggtccatcag tcttctggag ccctccttgg agctggagag cacctcagag    420

accagtgaca tgccagaggt cttctcttcc cacgagtctt cacatgaaga gcctctgcag    480

cccttcccac agcttgcaag gaccaaggga ggccagcagg tggacagggg gcctcagcct    540

gccctgaagt cccgccagtc agtggttacc ctccagggca gtgccgtggt ggccaaccgg    600

acccaggcct tccaggagca ggagcagggg caggggcagg ggcagggaaa cccctgcatt    660

tcctctacgc ccaggtccct gaaggggtga aaagccccca tatgcatgac agtgcatagg    720

aaggccacgc cttgacactc acacaagccc ctcctacccc taatatgaaa accaaccatc    780

ccaaccacga aacatatcac catcaccctc gcccacaaac acaccctaca tacccccccc    840

ctctcattcc acataaccac ctaacacata actgataaat ccatgaccca aacccccacc    900

caccaatact atccaaacct tctatacaac gcaaacctca caaaatatcc aactctaccc    960

cacgctctat aacacactac accccatccc cctctcactc aacataacat cacacacatc   1020

aacaaatact cactttttca gtcccactct accactaccc actcccccat ctcactcacc   1080

acactatcaa ccaacaacac caacaagccc attcaaaccc actccaccct cagaacacat   1140

agattccctc acccccatac atctaaaatc aaatcactcc aatccctcca cccctatttc   1200

tcaacatact acctcttccc ccctccacat aaaccattac cctcacatac cacatctcta   1260

acacaacttc tggagtaaca agatcatttg accatcaacc acgcacacta acactactca   1320

ccccacatta caaaattcaa tctaaactcc accaatatat cttttaatct tcaacaatct   1380

tgtctaat                                                            1388


<210>  198
<211>  879
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (11)..(12)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (14)..(15)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (38)..(38)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (50)..(50)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (56)..(56)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (59)..(59)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (69)..(69)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (101)..(101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (166)..(167)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (169)..(169)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (183)..(183)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (286)..(287)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (291)..(291)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (328)..(330)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (636)..(636)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (662)..(662)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (702)..(702)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (732)..(732)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (739)..(739)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (742)..(742)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (769)..(769)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (774)..(774)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (784)..(784)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (788)..(788)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (791)..(791)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (797)..(797)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (802)..(802)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (806)..(806)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (815)..(815)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (821)..(821)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (825)..(825)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (834)..(834)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (842)..(842)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (850)..(850)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (853)..(853)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (856)..(856)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (860)..(861)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (865)..(865)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (868)..(868)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (871)..(872)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (876)..(876)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (879)..(879)
<223>  n is a, c, g, or t

<400>  198
tgcaaaaatt nntnntaaaa ccccaattct ttaagccnga aataatttan ctatgnagng     60

gtttcgcanc accatacacc atcacggtat cctatttagg ngacactata aaatcgtcga    120

cccacgcgtc cgttttagaa ggtgttcact ttttacacac tcgggnngna gttcatcctg    180

atnagaagcc tcagaatatt ctgttgacaa gtgaatctcc attgggtgac attaagattg    240

ttgattttgg cctttcaaga atattgaaga acagtgaaga gctccnnttt nttatgggta    300

cccctgaata tgtggctcct gaaattgnnn gttatgatcc tataaccctg gcaacagata    360

tgtggagcat tggagtgtta acatatgtca tgcttacagg aatataacct ttcttaggca    420

atgataaaca agaaacattc ttaaacatct cacagatgaa tttaagttat tctgaggaag    480

aatttgatgt tttgtctgag tcggctgttg atttcatcag gacactttta gttaagaaac    540

ctgaagatcg agccactgct gaagaatgtc taaagcaccc ctggttgaca cagagcagta    600

ttcaagagcc ttctttcagg atggaaaagg cactanaaga agcaaatgcc ctccaagaag    660

gncattctgt gcctgaaatt aattcggata ccgacaaatc anaaaccgag gaatccattg    720

gaaccgaaga gntaattgna gntacttcat atactctagg acaatgcana cagnctgaaa    780

aganaaangg ngcaaanggc cntttnccaa acganttaaa nttgnggaac cttngctaca    840

anaaattccn ggnaanttan ntacnggnca nntttnccn                           879


<210>  199
<211>  1179
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (929)..(929)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (932)..(932)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (952)..(952)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (983)..(983)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (999)..(999)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1024)..(1024)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1038)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1046)..(1046)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1065)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1069)..(1069)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1109)..(1109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1112)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1121)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1128)..(1128)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1130)..(1130)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1152)..(1152)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1154)..(1154)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1159)..(1159)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1161)..(1162)
<223>  n is a, c, g, or t

<400>  199
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg ttgttcagtt gtgacatcag atagcttcaa    120

aacaaaagac agctttagaa ctgcaaaaag taaaaagaag aggcgaatca caaggtatga    180

tgcacagtta atcctagaaa ataactctgg gattcccaaa ttgactcttc gtaggcgtca    240

tgatagcagc agcaaaacaa atgaccaaga gaatgatgga atgaactctt ccaaaataag    300

catcaagtta agcaaagacc atgacaacga taacaatctc tatgtagcaa agcttaataa    360

tggatttaac tcaggatcag gcagtagttc tacaaaatta aaaatccagc taaaacgaga    420

tgaggaaaat agggggtctt atacagaggg gcttcatgaa aatggggtgt gctgcagtga    480

tcctctttct ctcttggagt ctcgaatgga ggtggatgac tatagtcagt atgaggaaga    540

aagtacagat gattcctcct cttctgaggg cgatgaagag gaggatgact atgatgatga    600

ctttgaagac gattttattc ctcttcctcc agctaagcgc ttgaggttaa tagttggaaa    660

agactctata gatattgaca tttcttcaag gagaagagaa gatcagtctt taaggcttaa    720

tgcctaagct cttggtctta acttgacctg ggataactac tttaaagaaa taaaaaattc    780

cagtcaatta ttcctcaact gaaagtttag tggcagcact tctattgtcc cttcacttat    840

cagcatacta ttgtagaaag tgtacagcat actgactcaa ttcttaagtc tgatttgtgc    900

aaatttttat cgtacttttt aaatagccnt cntacgtgca attctgagtt anaggtaaag    960

ccctgttgta aaataaaggc tcnagcnaaa ttgtacagng atagcacttt ccccncagga   1020

cgtngaaaac agtaatgngg ctaccngttt tttaactgna aaacntccnc tggctcttta   1080

tttttgacta accatatttt aaccaatcnt antaccccct nttagggntn ctagttgcta   1140

aatccccccc angnacttng nntttgattt tttgcaaag                          1179


<210>  200
<211>  879
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (745)..(745)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (747)..(747)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (753)..(772)
<223>  n is a, c, g, or t

<400>  200
aaaactatga gaggtcgcat caccatcacc atcacggatc ctatttaggt gacactatag     60

aatcgtcgac tctggacctt ggctgtcact cagttgaaat agccgcagcc tctgcgcgtc    120

gccctccacg gttaccgcgg ctctccgccc ctccttctcg cggcgctcga gggaccatgg    180

ccgatcctcg cgtgagacag atcaagatca agaccggcgt ggtgaagcgg ttggtcaaag    240

aaaaagtgat gtatgaaaaa gaggcaaaac aacaagaaga aaagattgaa aaaatgagag    300

ctgaagacgg tgaaaattat gacattaaaa agcaggctgg tcttcaactc ctggcctcca    360

gtgatcctcc caccccagcc tctcagagtc ctgggatgat aagcgcagag atcctacaag    420

aatccaggat gatgatccca gattgccagc gcaggttgga agccgcatat ttggatcttc    480

aacggatact agaaaatgaa aaagacttgg aagaagctga ggaatataaa gaagcacgtt    540

tagtactgga ttcagtgaag ttagaagcct gaaacttttc tcgtatgggg tggtttttgc    600

attaaatcct ggggtccatt ttacaatcca ttatttttga ccactgctat gtgttcaagt    660

agtatgagaa tgtgattgtt tttatctggt tacatatata tttctttgtc taatttaata    720

tgtcaaataa atgagttcat ctaananaaa aannnnnnnn nnnnnnnnnn nncgagcggc    780

cgctcctata gtgagtcgta ttagcttaat agctgagctg gactcctgtg ataatcagta    840

tgactcaaac tcatctggat tgtcaaacgc tcgtgcgcc                           879


<210>  201
<211>  743
<212>  DNA
<213>  Homo sapiens

<400>  201
ctatgagagg atcgcatcac catcaccatc acggatccta tttaggtgac actatagaat     60

cgtcgactct ggacttggct gtcactcagt taaatggtac tttcttcgtt taccatgcta    120

tctatctaga agaactaaca gctgttgaat tgacagaaaa aattgctcag cttttcagca    180

tttccccttg ccagatcagc cagatttaca agcaggggcc aacaggaatt catgtgctca    240

tcagtgatga gatgatacag aactttcagg aagaagcatg ttttattctg gacacaatga    300

aagcagaaac caatgatagc tatcatatca tactgaagta ggagtgcggc gtttcatgcc    360

cagtggctgc tccttccttc acctctgaaa acggccctct tgaaggggga tgtgaatgga    420

gatttgaagg tctgcaagaa cctgactcgt ctgactgtgt gtggaggagt ccaggccatg    480

gaggcagaat cctggccctc tgtgttggcc caagctcttg tggtacacac agattactgc    540

ccaatatgca gttctgcagc tgttttagtt aaatttctgg accttgttgt tgttaaatat    600

cagtagaaac tctacataat ttagagtgta tgtagggcat aatgatgatg ggaattgtgt    660

gatgtttaac aggaagatct taaattttgt gatatggagc cctgtaattt ttttcttata    720

taaaaatggg tatctatatt cat                                            743


<210>  202
<211>  1318
<212>  DNA
<213>  Homo sapiens

<400>  202
accacacccc gccccacccc cccccaagaa attactagag aggatcgcat caccatcacc     60

atcacggtcg acccacgcgt ccgcgcaggc gattcaacat taacgacagg atcaaggaac    120

tgggcactct catccctaag tccagtgacc cggagatgcg ctggaacaag ggcaccatcc    180

tgaaggcctc tgtggattat atccgcaagc tgcagaagga gcagcagcgc tccaaagacc    240

tggagagccg gcagcgatcc ctggagcagg ccaaccgcag cctgcagctc cgaattcagg    300

aactagaact gcaggcccag atccatggcc tgccagtacc tcccactcca gggctgcttt    360

ccttggccac gacttcggct tctgacagcc tcaagccaga gcagctggac attgaggagg    420

agggcaggcc aggcgcagca acgttccatg tagggggggg acctgcccag aatgctcccc    480

atcagcagcc ccctgcaccg ccctcagatg cccttctgga cctgcacttt cccagcgacc    540

acctggggga cctgggagac cccttccacc tggggctgga ggacattctg atggaggagg    600

aggagggggt ggtgggagga ctgtcggggg gtgccctgtc cccactgcgg cctgcctccg    660

atcccctgct ctcctcagtg tcccctgctg tctcccacgt caacaatccc cgcaacaacc    720

ttagcatgga agaccagccc tgcccaaatc ccccccatca catgaaaccc tcccccccta    780

caaacaagta cccacccaga cccatccccc actatatcac caccctccaa acaccaccac    840

cacccactcc ccatatccca ccaccaacca cccccaacac ccccctacca ccaccactca    900

ccctacaaca ctcaatccaa cactccatcc accttaccct cacaccatat tctatcccac    960

atactaccac caaccacccc catccaaaca ttacactacc caacacctcc actacccatc   1020

ctcccacaac aaccaaccca ccacaacaat ccacacataa ctcaataacc acaaccccac   1080

cccctatcaa cccaactttc cataaaaaca cattcctacc acccacaccc taccgcacac   1140

aatcaccact caccccacac cctaccttta ccaccacaca ccaccccaac acactcatcc   1200

aaccatcaac acacccacac cactaacacc tctccataac ttatcacaca actctcacca   1260

ccatcacaat ccctcataca aacatcccca ctcacaccat ccatcacctc aactccac     1318


<210>  203
<211>  617
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (42)..(42)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (46)..(47)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (52)..(52)
<223>  n is a, c, g, or t

<400>  203
tcgagaatnt aaaaattatt tgctttgtga gcggatacaa tntaanngat tnattgtgag     60

cggataacaa tttacacaga attcattaaa gaggagaaat taactatgag aggatcgcat    120

caccatcacc atcacggatc ctatttaggt gacactatag aatcgtcgac ccacgcgtcc    180

gagcacttcc ggccagagtg cttcagcgcc tttggaaacc gcaagaacct aaagcacaat    240

gccgtgccca cggtgttcgc ctttcaggac cccacacagc aggtgaggga gaacacagac    300

cctgccagtg agagaggaaa tgccagctct tctcagaaag aaaaggtcct ccctgaggcg    360

ggggccggag aggacagtcc tgggagaaac atggacactg cacttgaaga gcttcagttg    420

cccccaaatg ccgaaggcca cgtaaaacag gtctcgccac ggaggccgca agcaacagag    480

gctgttggcc ggccgactgg ccctgcaggc ctgagaagga cccccaacaa gcagccatct    540

gatcacagct atgccctttt ggacttagat tccctgaaga aaaaactctt cctcactctg    600

aaggaaaatg aaaagct                                                   617


<210>  204
<211>  852
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (712)..(712)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (761)..(761)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (804)..(804)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (820)..(820)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (842)..(843)
<223>  n is a, c, g, or t

<400>  204
ggaattacta tgagaggtcg catcccatca ccatcacgga tcctatttag gtgacactat     60

agaatcgtcg actctggacc ttggctgtca ctcagttaat gaacggtttg aacggttccg    120

aacaggccag accaccaagg ccccaagtga ggccgagccg gcagctgacc tgatcgacat    180

gggccctgac ccagcagcca ccggcaacct ctcatcccag ctggcaggaa tgaacctggg    240

ctccagcagt gtgagagctg gcctgcagtc tctggaggcc tctggtcgac tggaagatga    300

gtttgacatg tttgcgctga cacggggcag ctcactggct gaccaacgga aagaggtaaa    360

atacgaagcc ccccaagcaa cagacggcct ggctggagcc ctggacgccc ggcagcagag    420

cactggcgcg atcccagtca cccaggcctg cctcatggag gacatcgagc agtggctgtc    480

cactgacgtg ggtaatgatg cggaagagcc taagggggtc accagcgaag aatttgacaa    540

attcctgaaa gaacgggcca aagccgcgga ccgattgccc aacctctcca gcccctcagc    600

tgaggggccc ccgggtcccc catctggccc agcgccccgg aagaagaccc aggagaaaga    660

tgatgacgtg ctgtttgcct atgagtgtgg ggtctggcac cctgcagccc angtcccact    720

gctctcacac cttaggctgg gacctcctcc ctctcctgtg ntaggctgct ttggggggtg    780

cttggtaccc cctttctcct cttngagacg gactgcccan ctgtggctgg ggtgtggagc    840

annggataac tg                                                        852


<210>  205
<211>  1041
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1003)..(1003)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1011)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1013)..(1013)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1030)..(1030)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1039)..(1039)
<223>  n is a, c, g, or t

<400>  205
nantagagaa attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cgcgtccggc gcgatggcgg ggagtagctc    120

gctggaggcg gtgcgcagga agatccggag cctgcaggag caggcggacg ccgctgagga    180

gcgcgcgggc accctgcagc gcgagctgga ccacgagagg aagctgaggg agaccgctga    240

agccgacgta gcttctctga acagacgcat ccagctggtt gaggaagagt tggatcgtgc    300

ccaggagcgt ctggcaacag ctttgcagaa gctggaggaa gctgagaagg cagcagatga    360

gagtgagaga ggcatgaaag tcattgagag tcgagcccaa aaagatgaag aaaaaatgga    420

aattcaggag atccaactga aagaggcaaa gcacattgct gaagatgccg accgcaaata    480

tgaagaggtg gcccgtaagc tggtcatcat tgagagcgac ctggaacgtg cagaggagcg    540

ggctgagctc tcagaaggcc aagtccgaca gctggaagaa caattaagaa taatggatca    600

gaccttgaaa gcattaatgg ctgcagagga taagtactcg cagaaggaag acagatatga    660

ggaagagatc aaggtccttt ccgacaagct gaaggaggct gagactcggg ctgagtttgc    720

ggagaggtca gtaactaaat tggagaaaag cattgatgac ttagaagacg agctgtacgc    780

tcagaaactg aagtacaaag ccatcagcga ggagctggac cacgctctca acgatatgac    840

ttccatataa gtttctttgc ttcacttctc ccaagactcc ctcgtcgagc tggatgtccc    900

acctctctga gctctgcatt tgtctattct ccagctgacc ctggttctct ctcttaacat    960

cctgccttaa agccaggcac acactgtgct ttctatngta canaanctct ncntttcagt   1020

gtcaataacn ctgtgtaanc t                                             1041


<210>  206
<211>  1026
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (824)..(824)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (837)..(837)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (857)..(857)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (874)..(874)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (890)..(890)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (894)..(894)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (898)..(898)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (965)..(965)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (979)..(979)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1009)..(1009)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1016)
<223>  n is a, c, g, or t

<400>  206
tagagaaatt anctatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg cccggtgcgc gggtatggcg gccagcctgt    120

ggatgggcga cgtgagtgag ggcagccgtc cggggtctga agacaaggaa gcatctcggt    180

ttcgcgagag actggaaccc tacatggatg agaacttcat ctccagagcc tttgccacca    240

tgggggagac cgtaatgagc gtcaaaatta tccgaaaccg cctcactggg atcccagctg    300

gctactgctt tgtagaattt gcagatttgg ccacagctga gaagtgtttg cataaaatta    360

atgggaaacc ccttccagga gccacacctg cgaaacgttt taaactgaac tatgccactt    420

acgggaaaca accagataac agccctgagt attccctctt tgtgggggac ctgaccccgg    480

acgtggatga tggcatgctg tatgaattct tcgtcaaagt ctacccctcc tgtcggggag    540

gcaaggtggt tttggaccag acaggcgtgt ctaagggtta tggttttgtg aaattcacag    600

atgaactgga acagaagcga gccctgacgg agtgccaggg agcagtggga ctggggtcta    660

agcctgtgcg gcagagcacc atgcagacat atgaagaagt tggagatgat gcattggaag    720

accccatgcc acagctggat gtgactgagg ccaacaagga gttcatggaa cagagtgagg    780

agctgtatga cgctctgatg gactgtcact ggcagcccct gganacagtg tcttcanaga    840

tccctgccat gatgtancca ggccaaagga caancccagg ttgcatgatn tgangganat    900

gaaaaactcc tttttaaaaa ttgtgaaaac cttttttgga aaaaatgatt tggaaaaatt    960

ttaanaatga ctgtttttng anaatcatga atgtttntta naaaaactng ctggcntttc   1020

tttttg                                                              1026


<210>  207
<211>  1393
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (4)..(8)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1152)..(1152)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1182)..(1182)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1203)..(1203)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1223)..(1223)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1241)..(1242)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1272)..(1272)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1287)..(1287)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1344)..(1344)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1369)..(1369)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1375)..(1375)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1386)..(1386)
<223>  n is a, c, g, or t

<400>  207
aacnnnnnct aagagatact agagaggatg catcaccatc accatcacgg tcgacccacg     60

cgtccggaga aaaacccagt gttggtgtcc ccagagtttg tggatgaagc tctgtgtgcg    120

tgcgaggagt accttagcaa cttggcccac atggacatcg acaaggacct ggaggccccg    180

ctgtacctca cccccgaggg ctggtccctc ttcctccagc gctactacca agtggtccac    240

gaaggggcag aactcaggca cctcgacact caggtccagc gctgtgagga catcctgcag    300

cagctgcagg ccgtggtacc ccagatagac atggaagggg atcgcaacat ctggatcgtg    360

aagccaggag ccaagtcccg tggacgaggc atcatgtgca tggaccacct ggaggagatg    420

ctgaagctgg tgaacggcaa ccccgtggtg atgaaggacg gcaagtgggt ggtgcagaag    480

tatattgagc ggcccctcct catctttggc accaagtttg acctcagaca gtggttcctg    540

gtaactgact ggaacccact taccgtgtgg ttctaccgcg acagctatat ccgcttttcc    600

acgcagccct tctccctgaa gaacctggac aactcagtgc acctgtgcaa caactccatc    660

cagaagcacc tggagaactc atgccatcgg catccactgc ttccgccaga caacatgtgg    720

tctagccaga ggttccaggc ccacctgcag gagatgggtg ccccaaatgc ttggtccacc    780

atcatcgtgc ctggcatgaa ggatgctgtg atccacgcac ttcagacctc ccaggacacc    840

gtgcaatgtc ggaaggccag ctttgacctc tatggcgctg acttcgtgtt cggggaggac    900

ttccagccct ggctgattga gatcacgcca gcccccgatg gcaccctcca cacagtcact    960

gcccggctct gtgctggcgg gcaactgaaa ccttgcccgg ggctttacac caagccgccc   1020

cccaatgtga cacagagcct ttgacctctc tataaacacc tgctttgcag gtcctcatta   1080

ggcgcattcc tttcctgaag agagcttccc caaaaaccct tctgtatgtt tcctccgaga   1140

gagccctcct cnccccccct ccccaggact ccctgcacaa anaaccccgc ctatccctcc   1200

gcntcctttc tctctctcca acntacttcc tcccctcacc nnccaggccc ccacacaaac   1260

caccatttgg tntacccctc atccctntct cttctccccc ccatatttct tctctccccc   1320

tccctgtccc tcccccttcc taancttact tgccctcatt tcaaatccng caacntcccc   1380

gcaacntcct cta                                                      1393


<210>  208
<211>  1118
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (4)..(5)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (703)..(703)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (790)..(790)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (794)..(794)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (796)..(796)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (807)..(807)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (812)..(812)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (815)..(815)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (831)..(831)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (838)..(838)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (859)..(859)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (877)..(877)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (948)..(948)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (950)..(951)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (965)..(965)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (973)..(973)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (978)..(978)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (981)..(981)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (991)..(991)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (995)..(996)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1004)..(1004)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1008)..(1008)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1018)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1022)..(1022)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1025)..(1027)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1031)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1039)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1043)..(1043)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1052)..(1052)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1063)..(1064)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1067)..(1067)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1079)..(1079)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1112)
<223>  n is a, c, g, or t

<400>  208
anannagaga aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt tccggctcct tcgggaaacc cagccccgtc    120

accgggctcc gagcggctcg caggcgagcg acagcggcct cagccccggc agcgcccagc    180

ggcggctgcg gaaagcggag ggagtccgac gcgggcgcgg gcggggagcg tgcgtccgtt    240

cgcacaggca gcgggaggag gggcggcgcg aaccatggcc ggggacagcg agcagaccct    300

gcagaaccac cagcagccca acggcggcga gcccttcctt ataggcgtca gcgggggaac    360

agctagcggc aagtcttccg tgtgtgctaa gatcgtgcag ctcctggggc agaatgaggt    420

ggactatcgc cagaagcagg tggtcatcct gagccaggat agcttctacc gtgtccttac    480

ctcggagcag aaggccaaag ccctgaaggg ccagttcaac tttgaccacc cggatgcctt    540

tgacaatgaa ctcattctca aaacactcaa agaaatcact gaagggaaaa cagtccagat    600

ccccgtgtat gactttgtct cccattcccg gaaggaggag acagttactg tctatcccgc    660

aaacgtggtg ctctttgaag ggatcctggc cttctactcc cangaggtac gagacctgtt    720

ccagatgaag ctttttgtgg atacagatgc ggacacccgg ctctcacgca aaagtattaa    780

gggacatcan cgananaggc agggatnttg ancanatttt tatctcagta natttacntt    840

cgtcaagcct gcctttgang aaattctgct tgccaanaaa aaaatatgct gatgtgatca    900

tcccctaaag gtgcaaataa tttggtgggc cattaaactt cattgtgnan naaattcaga    960

aattnttgaa tgnagggncc ntccaaangg naaannaatg ggtntttnaa aggttaancc   1020

cnttnnncaa naggaaggnn ttngaaatcc anaaaaaggc ccnnttnaac ccgttttcna   1080

ttggaaccca cccctttttt naaaaaaaaa anaaaggg                           1118


<210>  209
<211>  821
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (764)..(764)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (775)..(775)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (784)..(784)
<223>  n is a, c, g, or t

<400>  209
ttanctatga gaggatcgca tcaccatcac catcacggat cctatttagg tgacactata     60

gaatcgtcga cccacgcgtc cggagttttg cacgtggatc gccgttcggg tgggcgagat    120

ggagacagcc cccaagccgg gcaaggatgt cccgcccaag aaagacaaac ttcagaccaa    180

gagaaagggc ctcctcgtaa caagaagaat cgggagctcc gtcctcagag accaaaaaat    240

gcttacatct taaagaagtc tcggatctct aagaagcctc aggtcccgaa gaaaccccga    300

gaatggaaga acccggagtc ccagcgcggc ttgtccgggg cccaagatcc attcccaggc    360

cccgcccccg tccctgtgga agtggtccag aagttctgtc gcattgacaa atcccgaaag    420

ctaccacatt ctaaagccaa aactcgaagc cgacttgagg tggctgaagc tgaggaagag    480

gaaacaagta tcaaagctgc tcgttctgag ctgctgcttg ctgaagaacc tgggtttctg    540

gaaggggagg atggggaaga cacagcaaag atatgccagg ctgacattgt ggaggctgtg    600

gacattgcaa gtgcagccaa gcactttgac ttgaatctgc ggcagtttgg accctacaga    660

ctaaactact ctcgaactgg aagacacctg gcttttggag ggcgccgagg tcatgtggct    720

gcccttgatt gggtaacaaa gaagcttatg tgcgagatca acgntcatgg gaggnggtgg    780

gggnacatcc ggttttctcc attctgaggc actggtttgc t                        821


<210>  210
<211>  850
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (652)..(654)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (656)..(656)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (658)..(661)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (664)..(666)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (802)..(802)
<223>  n is a, c, g, or t

<400>  210
atagggaaat actatgagag gacgcatccc atcaccatca cggatcctat ttaggtgaca     60

ctatacaatc gtcgactctg gaccttggct gtcactcagt tcagagggga gcaaaattat    120

gcgtggttaa aacccagcgg aaggcaaaac aagctgagac tctaactcag gactacatca    180

tcacccctca tgccttgcct atgttccgtg agccccgcca acggagtaca aggaaacagc    240

tggagaagga cagactggat cccctgaagt cgcataaacc tgaacctcct gtagcaggcc    300

caggtcgtgg tggccgagtt ggaacccacg ggggcactct ctcttcctat attgtgaaga    360

acattgcttt ggacaagacc gatgacagta atcctcggga agccattttg cgtcatgcca    420

aagcagcaga agacagccca tattgggttt ctccagcata ttccaagact cagcccaaaa    480

ccatgtttgc ccaagttgaa tctgatgatg aggaagcaaa gaatgagcca gaatggaaaa    540

aacgtaaaat ttgaagaatc tcatttgaga gctgtttgca tgagtgggag gggtatggga    600

caggtttggg ttttttttta tgctcatgaa attaaaaatt catttttatg annnanannn    660

naannnaaaa aaaaacgagc ggccgctccc tatagtgagt cgtattaagc ttaattagct    720

gagcttggac tcctgttgat agatccagta atgacctcag aactccatct ggattttgtc    780

agaacgctcg gttgccgccg gncgtttttt attgtgagaa tccagctagc ttggcgagat    840

ttcaggagct                                                           850


<210>  211
<211>  1239
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (889)..(889)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (927)..(927)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (968)..(968)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1021)..(1021)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1023)..(1023)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1034)..(1034)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1037)..(1037)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1044)..(1045)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1050)..(1050)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1057)..(1057)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1068)..(1068)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1072)..(1072)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1082)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1100)..(1100)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1113)..(1113)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1115)..(1115)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1119)..(1120)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1130)..(1130)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1140)..(1140)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1145)..(1145)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1148)..(1148)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1151)..(1151)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1158)..(1158)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1166)..(1166)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1168)..(1168)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1186)..(1186)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1191)..(1191)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1196)..(1196)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1199)..(1199)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1204)..(1204)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1209)..(1210)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1216)..(1216)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1219)..(1219)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1223)..(1223)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1226)..(1226)
<223>  n is a, c, g, or t

<400>  211
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg cctcactgtc aacccccagg acaacaactg    120

cctggcagtt ggggccagcg ggcccttcgt gaggctctat gacatccgca tgatccataa    180

ccacagaaag agcatgaagc agagcccttc agcgggtgtg cacaccttct gtgaccggca    240

gaaacccctt ccggacggtg cagcccagta ttacgtagca ggtcacctgc cagtgaagct    300

tcctgactac aacaaccgtt tgagagtgct ggttgccacc tatgtgacct tcagccccaa    360

tggcacagag ctactagtca acatgggggg ggaacaggtc tatttgtgct ggttgccacc    420

tatgtgacct tcagccccaa tggcacagag ctactagtca acatgggggg ggaacaggtc    480

tatttgtttg acttgactta caagcagcgg ccgtacacct tcctcttgcc tagaaaatgc    540

cactcctcgg gggaagtcca gaatggcaag atgtccacca ccgttggaca caccgttgag    600

cggccgctcc ctatagtgag tcgtattaag cttaattagc tgagcttgga ctcctgttga    660

tagatccagt aatgacctca gaactccatc tggatttgtt cagaacgctc ggttgccgcc    720

gggcgttttt tattggtgag aatccaagct agcttggcga gattttcagg agctaaggaa    780

gctaaaatgg agaaaaaaat cactggatat accaccgttg atatatccca atggcatcgt    840

aaagaacatt ttgaggcatt tcagtcagtt gctcaatgta cctataacna gaccgttcag    900

ctggatatta cggccttttt aaagacngta aagaaaaata agcacaagtt ttatccggcc    960

tttattcnca ttcttgnccc ccctgangaa tgctcatccg naattcctat ggcaatgaaa   1020

nanggggaac tggngantgg aaanngttcn ccttgtnacc cgttttcntg ancaaactga   1080

angtttttct cccttggagn gaaacnccaa aantncggnn gttttaaaan attccaaatn   1140

ggggntangg naaactgnct attccnangg ttttgaaaaa tttttncccc ncccanccng   1200

gggnttccnn tttttnaang gcnaangaaa aatttcccc                          1239


<210>  212
<211>  1183
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (15)..(15)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (921)..(921)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (927)..(927)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (964)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (976)..(976)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (992)..(992)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (999)..(999)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1007)..(1007)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1017)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1024)..(1024)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1044)..(1044)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1060)..(1060)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1066)..(1066)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1068)..(1068)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1072)..(1072)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1076)..(1076)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1081)..(1081)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1088)..(1088)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1097)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1102)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1105)..(1105)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1118)..(1118)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1125)..(1125)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1129)..(1129)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1136)..(1136)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1139)..(1139)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1155)..(1155)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1160)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1168)..(1168)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1177)..(1177)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1179)..(1181)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1183)..(1183)
<223>  n is a, c, g, or t

<400>  212
naatagagaa attanctatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgaagcctt catccagagc tccaagctgc    120

ttctgcacca gattattcac actggagaaa agccctatgt gtgcagttat tgtgggaaag    180

gctttattca gaggtcaaac ttccttcaac accagaaaat tcatactgaa gagaagctct    240

atgaatgtag tcagtatggg agagatttta actcaactac aaacgttaaa aataatcaaa    300

gggttcacca agagggactc tccttgagta aggcccccat acatttgggt gagaggtctg    360

tagataaggg ggaacacaca ggtaacttat aaaataatta ctttcccgcc cagtgagtga    420

tgtttggaaa tgcgtggaat taggattcat gtggtttcta agatttggac atgtcagaat    480

tttgtgagtc atggatgggg ctgcttttgc agtgggtgcc acctgccact gtgcagccct    540

actcggctca gcccttctcc tcagctgtga gcactgtcct caggagagtc acagggcttg    600

acacctgact ctgagctgga acagtagggg cagggagaag acaggtctca agaaaaggtt    660

tttaagaagt ttcatcccca gttaagcaga gtccatcctt gacttaaatc ccttattaca    720

gcacaactgt gtatctaatc ttacgattta ggagaatgtt acctaggaca ttttgatgtg    780

ttaagttgaa gaaaggtaac tcgtgtatga accccgagcc atttccctgt tgtcctgagg    840

aggaactcca ggcctcccat cgtgtgccct aaggcctcct gcgtcctgga gccctgcctc    900

ccactgcctg acttcctgcc ncacggntta atgctgcagc aacaccgact gcttcatctt    960

cccnggtgct ccacgnggct tcctacctct cncgccttng ttcctgnttg aaggnnncct   1020

cccnccttat taacnctgaa tcanggttca aaaaagcccn caggcntnct gnccangggg   1080

ngtttccncc agcctanntg gnccnccccc cccccttngg ggccnaggna taccgncant   1140

acaaattttc ctgcnaaggn caaaaggnag ggaaaanann ncn                     1183


<210>  213
<211>  1202
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (927)..(927)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (936)..(936)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (999)..(999)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1024)..(1024)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1034)..(1034)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1044)..(1044)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1056)..(1056)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1065)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1068)..(1068)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1079)..(1079)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1081)..(1081)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1083)..(1083)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1130)..(1130)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1139)..(1139)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1158)..(1159)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1172)..(1172)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1176)..(1176)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1188)..(1192)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1195)..(1195)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1197)..(1198)
<223>  n is a, c, g, or t

<400>  213
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc tctggttctc gggacagcag ccacggttct    120

gcagcagggc agcttcagtg tggatgacgt gcagactgtg agtgcaggag cattaggctg    180

tctggtggct ctgcccatga agaacttgag tgacgaccca ctggctttga cctccaatag    240

taacttagca gcacatatca ccacaccgac ctcttcgagc accccccgag aaaatgccag    300

tgtcccggaa ctgctggctc caatcaaggt ggagccggac tcgccttctc gcccaggagc    360

agttgggcag caggaaggaa gccatgggct gccccagtcc acgttgccca gtccagcaga    420

gcagcacggt gcccaggaca cagagctcag tgcaggcact ggcaacttct atttggaaag    480

tgggggctca gcaagaactg attaccgagc cattcaacta gccaaggaaa aaaagcagag    540

aggagcgggg agcaatgcag gtgaggccgt gtgtgctgca gccggacgag caagggcctg    600

agggttctct gtcactgtta ctggcagaag aaacacagca ggtgtttctg tgctcttggt    660

tttacttttc tgttcagaat acccttttat caactcctta gttttatttg aacttaaggg    720

aaaaaattag taacaaaatt cccagcatca gtatgaacat attttatttg cctaaacaag    780

ctttgtgaaa gttaagcgtt caaacaccag tgtcagttac ctggaaggct actaaggtaa    840

ataagcaaag caggccagtt gtcaggaaag cagagattgt gcctggtgct gaatggcctt    900

gggggcctga tcttggcatg gcaaaanacc tggggnactg ccactgttcc ccaggtacgt    960

gtacatggag cccaaactgt gtgttcctgt ggcatttgnc naatttttgt tgaantctta   1020

tttnaaaatg ttancaactt actngcattt tttaanaacc aaaanaanan ctggtaacnt   1080

ntnggcctca agcatttgtt ctttcttaaa atgaaaaaat gggaattagn gcttaaagna   1140

aactgcttaa tttttttnnt aaaaactaac gnggantttt taaatttnnn nnaanannaa   1200

aa                                                                  1202


<210>  214
<211>  856
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (427)..(427)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (533)..(533)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (584)..(584)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (666)..(666)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (670)..(670)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (684)..(684)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (725)..(725)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (745)..(745)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (752)..(752)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (765)..(765)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (770)..(770)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (776)..(776)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (787)..(787)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (789)..(789)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (797)..(797)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (800)..(801)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (808)..(808)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (811)..(811)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (813)..(813)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (817)..(817)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (829)..(831)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (834)..(834)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (847)..(847)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (849)..(849)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (855)..(855)
<223>  n is a, c, g, or t

<400>  214
tagagagatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc cggaccggga cgcagagtct gcggacccgg    120

cgccgaggcg gccacccgag acgcggcgcg cacgctccgg cctgcgcccg gcccggccat    180

ggcggccccc cgcccgtctc ccgcgatctc cgtttcggtc tcggctccgg ctttttacgc    240

cccgcagaag aagttcggcc ctgtggtggc cccaaagccc aaagtgaatc ccttccggcc    300

cggggacagc gagcctcccc cggcacccgg ggcccagcgc gcacagatgg gccgggtggg    360

cgagattccc ccgccgcccc cggaagactt tcccctgcct ccacctcccc ttgctgggga    420

tggcgangat gcatagggtg ctctgggagg tgccttcccg ccgccccctc ccccgatcga    480

ggaatcattt ccccctgcgc ctctggagga ggagatcttc ccttccccgc cgnctcctcc    540

ggaggaggag ggagggcctg aggcccccat accgccccca ccanagccca gggagaaggt    600

gagcagtatt gatttggaga tcgactctct gtcctcactg ctggatgaca tgaccaagaa    660

tgatcntttn aaagcccggg tgtnatctgg atatgtgccc ccaccagtgg ccacttccat    720

ttcanttcca agtccagtac caaancctgc anccgggggc aaaanacccn tgcctncttt    780

ggaagtncnc tttcagnttn ncagcctntg ncnaaanttt cggccttcnn nctnaaagcc    840

aaaaaanant ttccnt                                                    856


<210>  215
<211>  942
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (690)..(690)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (699)..(699)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (711)..(711)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (727)..(727)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (747)..(747)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (755)..(755)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (757)..(757)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (764)..(764)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (768)..(768)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (784)..(784)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (791)..(791)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (797)..(797)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (799)..(799)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (808)..(808)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (810)..(811)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (813)..(813)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (824)..(824)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (829)..(829)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (839)..(839)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (857)..(858)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (874)..(874)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (877)..(878)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (893)..(893)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (920)..(920)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (924)..(924)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (930)..(931)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (937)..(937)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (939)..(939)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (942)..(942)
<223>  n is a, c, g, or t

<400>  215
nnattagaga aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgcggacgc gtgggtcggc atcgacacca    120

tcatcgagca gatgcgcaag aagaccatga agaccggttt cgacttcaac atcatggtcg    180

ttggccagag tggactgggc aaatcaacgc tggtcaacac gctcttcaaa tcccaagtga    240

gccgcaaggc ctccagctgg aaccgggagg agaagatccc caagacagtg gagatcaaag    300

ctatcgggca tgtgatagag gaaggcggtg tcaaaatgaa gctgaccgtc atcgacaccc    360

caggctttgg agaccaaatc aacaatgaaa actgctggga gcccattgag aagtacatca    420

atgagcagta cgagaagttc ctgaaggagg aggtcaacat cgccaggaag aaacgcatcc    480

ctgacactcg tgtccactgc tgcctttact tcatctctcc cacaggacac tccttgcgac    540

ctctggatct tgagttcatg aaacacctca gcaaggttgt gaacatcatc cctgtcattg    600

ctaaggctga caccatgacc ctggaggaga agtctgaatt caagcaaagg ggttcgcaag    660

gagcttgaag taaatggcat tgaattctan ccccagaang aatttgatga ngatttggag    720

gataaanacg gagaatgacc aaatccnggc agganancat gccntttngc tgtgggtggg    780

aaantgacaa ngggtancna agtgaatngn nanaagggtc ctcnggccna aaaactccnt    840

ggggggatcc atccaanntg gaaaaaacct caancanngg ggaattttgc ccnggctttc    900

caaaactttt ttccttccan gaancccccn ncccggnanc cn                       942


<210>  216
<211>  949
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (842)..(842)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (890)..(890)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (893)..(893)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (914)..(914)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (923)..(923)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (930)..(930)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (938)..(938)
<223>  n is a, c, g, or t

<400>  216
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc ccacgcgtcc gcccacgcgt ccgagcagtt    120

tgagcagtac ttccgtgatg agagcggcct caaccgaaag aacatccaag acaaccgagt    180

gcactgctgc ctatacttca tctccccctt cgggcatggg ctgcggccag tggatgtggg    240

tttcatgaag gcattgcatg agaaggtcaa catcgtgcct ctcatcgcca aagctgactg    300

tcttgtcccc agtgagatcc ggaagctgaa ggagcggatc cgggaggaga ttgacaagtt    360

tgggatccat gtataccagt tccctgagtg tgactcggac gaggatgagg acttcaagca    420

gcaggaccgg gaactgaagg agagcgcgcc cttcgccgtt ataggcagca acacggtggt    480

ggaggccaag gggcagcggg tccggggccg actgtacccc tgggggatcg tggaggtgga    540

gaaccaggcg cattgcgact tcgtgaagct gcgcaacatg ctcatccgca cgcatatgca    600

cgacctcaag gacgtgacgt gcgacgtgca ctacgagaac taccgcgcgc actgcatcca    660

gcagatgacc agcaaactga cccaggacag ccgcatggag agccccatcc cgatcctgcc    720

gctgcccacc ccggacgccg agactgagaa gcttatcagg atgaaggatg aggaactgag    780

gcgcatgcag gagatgctgc agaggatgaa gcagcagatg caggaccagt gacgctcgcc    840

gnggacacac cgtccgtctc cgggacgccc tcgcaccccc tggacaccan acnggactgt    900

tcccgacccg gaanacgcgg ggnccacagn cccccagntg acccctaat                949


<210>  217
<211>  1261
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (842)..(842)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (873)..(873)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (904)..(904)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (922)..(922)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (942)..(942)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (944)..(944)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (947)..(947)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (951)..(951)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (962)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (967)..(967)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (995)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1003)..(1003)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1008)..(1008)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1041)..(1041)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1079)..(1079)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1083)..(1083)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1088)..(1088)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1092)..(1093)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1105)..(1105)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1108)..(1109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1118)..(1118)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1151)..(1151)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1166)..(1166)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1176)..(1176)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1198)..(1198)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1216)..(1216)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1219)..(1219)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1224)..(1225)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1229)..(1229)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1232)..(1232)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1236)..(1236)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1240)..(1240)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1249)..(1249)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1251)..(1251)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1254)..(1254)
<223>  n is a, c, g, or t

<400>  217
ctattagaga aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccggcgaggc ggaccctgaa gcggaccccg    120

aggaagccac tgctgccagg gtgattgaca ggtttgatga aggggaagat ggggaaggtg    180

atttcctagt agtgggtagc attagaaaac tggcatcagc ctccctcttg gacacggaca    240

aaaggtattg cggcaaaacc acctctagaa aagcatggaa tgaagaccat tgggagcaga    300

ctctgccagg atcgtctgat gaggaaatat ctgatgagga agggtctgga gatgaagatt    360

cagagggact gggtctggag gaatatgatg aggacgacct gggtgctgct gaggaacagg    420

agtgtggtga tcacagggag agcaagaaga gcagaagcca ctctgcaaaa acaccgggct    480

tcagtgtcca gagtatcagt gactttgaga aatttaccaa gggaatggat gaccttggga    540

gcagtgagga ggaggaagac gaagagagtg gcatggaaga aggggatgac gcggaagact    600

cccaaggcga gagtgaggaa gacagggctg gagatagaaa cagtgaggat gatggtgtgg    660

tgatgacctt ctctagtgtc aaagtttctg aggaagtgga gaaaggaaga gccgtgaaga    720

accagatagc actgtgggac cagctcttgg aaggaaggat caaactacaa aaagctctgt    780

tgaccaccaa ccagcttcct caaccagatg ttttcccatt gttcaaggac aaaggtggcc    840

cnaaaatttt ccagtgcccc tgaaaaatag tcncaaggca ctttaaagca ttgttgaggt    900

catnggtagg tcttccagga anagttgctt ttccagtacc cnanacncta natatctagt    960

anatggnaca aagcccnatg cgggaagtgg agganatttc tantgaanat gatgacctgn   1020

taaaaaaaaa aaacccccac naaaaaaggt ccctgccaaa aagaaactgg aaatggagna   1080

ctntcccncc tnntgggcaa ncccnttnnc ccattttnag tctacggaac cccccccttc   1140

aaaattggcc naaaaaaccc aactgntttc tgaaanctgg gaaagggttt tggggccntt   1200

taacccaaaa cttggnccna atcnnccant tntganggan aaaaaaatnt nttnaaagaa   1260

a                                                                   1261


<210>  218
<211>  764
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (739)..(739)
<223>  n is a, c, g, or t

<400>  218
nnnccataga gaaatactat gagaggatgc atcccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga ctctggacct tggctgtcac tcagtttatg aggtgacaag    120

agcccgagag ctgaaccagc tgctggggcc caaggcctcg ggccaggcct ttgactttgt    180

ccttgacctg cacaacacca cggccaacat gggcacctgc ttaatcgcga agtcctccca    240

cgaagtcttt gccatgcacc tgtgccgcca tctgcagctg cagtaccccg agctgtcctg    300

ccaggtcttc ctgtaccagc ggtctgggga ggagagctac aacctggact ctgtggccaa    360

aaatggactg ggtctggagc tgggccccca gccacagggt gtgctgcggg ctgacatttt    420

ctcaaggatg aggaccctgg tggccacagt tctggacttc atcgaactct tcaaccaggg    480

tacggccttt cctgcctttg agatggaagc ccatagaccc gtgggcgtcg tggacttccc    540

ccgcaccgag gccgggcacc tggcaggcac tgtgcatcct cagctgcagg accgagactt    600

ccagccactg cagcctggtg ctccatcttc cagatgttca gtggggagga cctgctctat    660

gagggagagt ccacggtgta ccccgtgttc attaacgaag ctgctactat gagaagggcg    720

ttgcctttgt caaactgana agtcacattc ccgtgcctgc atgc                     764


<210>  219
<211>  816
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (692)..(692)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (749)..(749)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (786)..(786)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (815)..(816)
<223>  n is a, c, g, or t

<400>  219
gatactatga gaggtcgcat cccatcacca tcacggatcc tatttaggtg acactataga     60

atcgtcgact ctggaccttg gctgtcactc agttccctgc ctggcgactc tccccctgca    120

gtgctcagta acctgtggca acggcaccca ggagcggcca gtgctctgcc gcaccgcgga    180

cgacagcttc ggcatctgcc aggaggagcg tcctgagaca gcgaggacct gcaggcttgg    240

cccctgtccc cgaaacatct cagatccctc caagaagagc tacgtagttc agtggctgtc    300

ccgcccggac cccgactcgc ccatccggaa gatctcgtca aagggccact gccaaggcga    360

caagtcaata ttctgtagga tggaagtctt gtcccgctat tgctccatcc caggctacaa    420

caagctgtgc tgcaagtcct gtaacctgta caacaacctc accaacgtgg agggcaggat    480

agagccaccg cctgggaagc acaacgacat tgacgtgttc atgcctaccc tcccagtgcc    540

cactgtagcc atggaggtgc ggccatcacc aagcaccccc ctggaggtcc ctctcaatgc    600

ctccagcacc aatgccacag aggatcaccc agaaaccaat gccgtagatg aaccctacaa    660

aatccatggc ctggaagatg aagtccagcc ancccaccta atccctcgac gaccgagccc    720

ctatgaaaag accagaaacc aaagatccna gagctcattg atgagatgcg gaagaaagag    780

atgctncgaa agttttctat aaatggggaa gatann                              816


<210>  220
<211>  932
<212>  DNA
<213>  Homo sapiens

<400>  220
cgcatcacca tcaccatcac ggatcctatt taggtgacac tatagaatcg tcgacccacg     60

cgtccggtgg cttagagaag aaaacgcagg ttctgcagcc tgaggagaag aagactgtgg    120

cataccacga agcaggccat gcggttgccg gctggtatct ggagcacgca gacccgcttt    180

taaaggtatc catcatccca cgtggcaaag gactaggtta tgctcagtat ttaccaaaag    240

aacaatacct ctataccaaa gagcagctct tggataggat gtgtatgact ttaggtggtc    300

gagtctctga agaaatcttc tttggaagaa ttacaactgg tgctcaagat gacttgagaa    360

aagtaactca gagtgcatat gcccaaattg ttcagtttgg catgaatgaa aaggttgggc    420

aaatctcctt tgacctccca cgtcaggggg acatggtatt ggagaaacct tacagtgaag    480

ccactgcaag attgatagat gatgaagtac gaatacttat taatgatgct tataaaagaa    540

cagtagctct tctcacagaa aagaaagctg acgtggagaa ggttgctctt ctgttgttag    600

aaaaagaagt attagataag aatgatatgg ttgaactttt gggccccaga ccatttgcgg    660

aaaaatctac ctatgaagaa tttgtggaag gcactggcag cttggatgag gacacctcac    720

ttccagaagg ccttaaggac tggaacaagg agcgggaaaa ggagaaagag gagcccccgg    780

gtgagaaagt tgccaactag aggcccagag ggaggccatc tcagtctgtc cactgtggtt    840

tcagccggtg cattatttca gctgtggctt tcagaagaat gggaatgctg cgctgatttt    900

agccagccac tggcccagct gaaatgatgg gg                                  932


<210>  221
<211>  1279
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (876)..(876)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (946)..(946)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (951)..(951)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (955)..(955)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (959)..(959)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (985)..(985)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (994)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1009)..(1009)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1021)..(1021)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1036)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1062)..(1062)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1092)..(1092)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1099)..(1099)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1103)..(1103)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1120)..(1120)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1125)..(1125)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1127)..(1127)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1146)..(1146)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1150)..(1150)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1164)..(1164)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1177)..(1178)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1186)..(1186)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1189)..(1191)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1194)..(1194)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1196)..(1196)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1200)..(1200)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1204)..(1206)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1216)..(1216)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1218)..(1218)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1222)..(1222)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1234)..(1234)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1238)..(1238)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1243)..(1243)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1248)..(1248)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1254)..(1254)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1257)..(1257)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1260)..(1260)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1270)..(1270)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1274)..(1274)
<223>  n is a, c, g, or t

<400>  221
aatagagaga ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gcccacgcgt ccgcagaaat ggattcgaaa    120

taccagtgtg tgaagctgaa tgatggtcac ttcatgcctg tcctgggatt tggcacctat    180

gcgcctgcag aggttcctaa aagtaaagct ctagaggccg tcaaattggc aatagaagcc    240

gggttccacc atattgattc tgcacatgtt tacaataatg aggagcaggt tggactggcc    300

atccgaagca agattgcaga tggcagtgtg aagagagaag acatattcta cacttcaaag    360

ctttggagca attcccatcg accagagttg gtccgaccag ccttggaaag gtcactgaaa    420

aatcttcaat tggactatgt tgacctctat cttattcatt ttccagtgtc tgtaaagcca    480

ggtgaggaag tgatcccaaa agatgaaaat ggaaaaatac tatttgacac agtggatctc    540

tgtgccacat gggaggccat ggagaagtgt aaagatgcag gattggccaa gtccatcggg    600

gtgtccaact tcaaccacag gctgctggag atgatcctca acaagccagg gctcaagtac    660

aagcctgtct gcaaccaggt ggaatgtcat ccttacttca accagagaaa actgctggat    720

ttctgcaagt caaaagacat tgttctggtt gcctatagtg ctctgggatc ccatcgagaa    780

agaaccatgg gtggacccga actccccggt gctcttggag gacccagtcc tttgtgcctt    840

ggcaaaaagc acaagcgaac cccagcccct gattgncctg cgctaccaac tgcagcgtgg    900

ggttgtggtc ctggccaaaa gctaccatga gcagcgcatc aaacanaacg ngcangtgnt    960

tgaattccag ttgacttccg aaganatgaa gccnnanatg gcctaacana aatgngcgaa   1020

nttttgaccc ttgaantttt ggcgggcccc cctaattatc cnttttcgga ngaaaattaa   1080

catggaaggc cntgcttgng gcngcccaaa agccctgcgn gggangngaa cccaagaaag   1140

gccctngcgn ggggacggga ccancccccc gggtaanncc cccgcnggnn nctncngaan   1200

cctnnnctaa cccccncncg gnaaaaaaaa aaantttntt ttnttttnaa aaanaangcn   1260

cccccaaaan ttcncccaa                                                1279


<210>  222
<211>  1303
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (831)..(831)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (857)..(857)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (980)..(980)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1029)..(1029)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1033)..(1033)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1079)..(1079)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1109)..(1109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1114)..(1114)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1123)..(1123)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1138)..(1138)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1147)..(1148)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1153)..(1153)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1163)..(1163)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1174)..(1174)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1178)..(1178)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1181)..(1181)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1186)..(1186)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1190)..(1190)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1198)..(1198)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1200)..(1200)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1209)..(1209)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1214)..(1214)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1216)..(1216)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1227)..(1227)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1230)..(1230)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1232)..(1232)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1254)..(1254)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1256)..(1257)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1270)..(1271)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1280)..(1281)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1289)..(1289)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1291)..(1294)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1299)..(1299)
<223>  n is a, c, g, or t

<400>  222
aatagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gcccacgcgt ccggagagaa cttggatgag    120

aatttggttc ctgtagcagc agccgaaggg agacctcgct taaaccaaca caatcacttc    180

ttccatttcg atgggtctcg gattgcgagc tggctgccga gtttttcggt tgaagtgatg    240

cacaccacca acattcttgg cattacgcag gccagcaact cccagctcaa tgcaatggct    300

catcagattc aagagatgtt tccccaggtt ccataccatc tggtactgca ggacctccag    360

ctgacacgct cagttgaaat aacaacagac aatattttag aaggacggat tcaagtacct    420

tttcctacac agcggtcaga tagcatcaga cctgcattga acagtcctgt ggaaaggcca    480

agcagtgacc aggaagaggg agaaacttct gctcagaccg agcgtgtgcc actggacctc    540

agtcctcgcc tggaggagac gctggacttc ggcgaggtgg aagtggagcc cagtgaggtg    600

gaagacttcg aggctcgtgg gagccgcttc tccaagtctg ctgatgagag acagcgcatg    660

ctggtgcagc gtaaggacga actcctccag caagctcgca aacgtttctt gaacaaaagt    720

tctgaagatg atgcggcctc agagagcttc ctcccctcgg aaggtgcgtc ctctgacccc    780

gtgaccctgc gtcgaaggat gctggctgcc gccgcggaac ggaggcttca naagcagcaa    840

acctcctagc gctcccnttg ccttcctcag ctgcctcctg cgcccctgtg cccgactgac    900

tggagggagg cctgtcccaa ttctgcccgc tccatggaaa aacgggcttg actgcattgc    960

cgctgtataa agcatgnggn cttatagtgt ttggacagct gaaaaattaa tcccttcttt   1020

ggaaaaacnt ttntatggga catttttcct ccccttaaaa accctgcaaa tttttactng   1080

gagggaggat ccccttcngg gggttnacng gaangcttgg ggngggggga aaaatcanga   1140

agaaaannaa aantccccct gcntggaaaa ggantttnaa ntctgncctn aggaaaantn   1200

cccaaaagna gggntncgga acccccnccn anggaaaagg gggggaagcc aaangnnacc   1260

cccccccccn nggggaaacn nttaaaaang nnnnttttng gaa                     1303


<210>  223
<211>  1134
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (933)..(933)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (962)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (980)..(980)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1021)..(1021)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1039)..(1039)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1062)..(1062)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1074)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1089)..(1089)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1093)..(1093)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1099)..(1099)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1103)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1113)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1117)..(1117)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1124)..(1124)
<223>  n is a, c, g, or t

<400>  223
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg ttatcatcaa caagaccagc agcaccagaa    120

ttcagtttgc tcccaggaaa gcctttttgt ggaaaacagt aggctcttgg aagacagtaa    180

catatgcaat gagacctata agaaaagaca gctctttcgg ggcaacagag atggctcagg    240

gagaacatct gggagtcgac agagcagctc agaaaatgaa ctcaagtggt ctgaccacca    300

aagggcctgg agcagcacag actccgacag ttccaaccgc aatctaaagc ccgccatgac    360

caagacggcg agttttgggg gcatcacggt gctgaccagg ggtgacagca cttccagtac    420

taggagtacc gggaagctgt ccaaagcagg ttccgagtct tccagcagtg caggctcctc    480

aggatcgctg tcccgcaccc atccacctct ccagagcaca cccctagtct caggtgtggc    540

agctggctct ccaggctgtg tgccttatcc agagaatgga atagggggcc aggttgctcc    600

cagcagcacc agctacatcc tccttccact tgaagctgca acaggcatcc cgcctggaag    660

catccttctt aatccacaca caggccagcc ctttgtgaat cccgatggaa ctcctgcaat    720

atacaaccca cccaccagtc agcagcccct gcgaagcgcc atggtggggc agtcccaaca    780

gcagccacca cagcagcagc cctccccgca gccccaacag caggtccagc caccgcagcc    840

acagatggca ggccctctgg tcactcagtc tgtccagggg ctgcaggctt cctcccagtc    900

agtgcaatat ccagcagtct cttttcctcc ccnagcacct cctacctgtg tctccaacgc    960

ancacttttc ccatganaan atgatgtggc aacccagttt gggcnaaatg accctgaacc   1020

nggcagtccc tcgggggana actcctgaac ccccatcagg gnctggtcta cccnatcctc   1080

cctttggcna aanccnggnc cannancccn anntttngta atcncctttt aaag         1134


<210>  224
<211>  1095
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (810)..(810)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (839)..(839)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (850)..(850)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (856)..(856)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (916)..(916)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (930)..(930)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (964)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (967)..(967)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (995)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1007)..(1007)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1011)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1043)..(1043)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1052)..(1052)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1067)..(1067)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1069)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1073)..(1073)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1076)..(1076)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1082)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1088)..(1088)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1090)..(1090)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1092)..(1092)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1095)
<223>  n is a, c, g, or t

<400>  224
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc ccacgcgtcc gcccacgcgt ccggcgggct    120

gccggtgctt gtggaactgc tgcagtctga gaccgacaag gtggtgcgcg ccgtcgccat    180

cgctctgcgc aacctctcgc tggaccggcg caacaaagac ctcatcggga gctacgccat    240

ggctgagctt gtgcggaatg tgcgcaatgc acaggctccg ccgcgaccgg gggcctgcct    300

ggaggaagac accgtggtgg cggtgctcaa caccatccac gaaatcgtgt ccgacagcct    360

ggataacgcg cgctcgctcc tgcaggcacg cggggtgcca gcgttggtgg ctctcgtggc    420

ctccagccaa tcggtacgcg aagcgaaggc ggcgtcacac gtgctgcaga cagtgtggag    480

ctacaaggag ctgcgtggta ccttgcagaa agatggttgg accaaggcgc gcttccagtc    540

agctgctgct actgccaagg ggcctaaggg agcactgagt cctgggggct tcgatgacag    600

cacgctgcca ctggtggaca agagccttga gggcgagaaa actggcagcc gggatgtgat    660

ccccatggat gcgctgggcc cagacggata ctccacggtg gaccagaggg agcggaggcc    720

acggggcgcc agctctgcag gagaggcctc tgagaaggaa cccttgaaac tcgaccccag    780

caggaaggcc cctccccccg ggcccagcan gcccgcggtc aggctggtgg acgccgtang    840

ggacgctaan cctcancccg ttgattcctg ggtctagctt gcatgcctgg gcccaggccc    900

agcctcttgt tcttanggct tggatcgtgn aaaaaggcca ccctgaacaa atcgtgccgt    960

gganctngaa ccccctggcg gcaggggttg gcacncctcc cccancnaac ntganttggg   1020

gaaaccttct gcccccaacc cantccccca tntaataaat cctaagncnn aantantgtt   1080

antgaaangn gntnn                                                    1095


<210>  225
<211>  898
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (827)..(827)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (855)..(855)
<223>  n is a, c, g, or t

<400>  225
agatactatg agaggatcgc atcaccatca ccatcacgga tcctatttag gtgacactat     60

agaatcgtcg actctggacc ttggctgtca ctcagttggg cgtcggggag cggcggtacc    120

gggcggctgc ggggctggct cgacccagct tgaggtctcg gcgtccgcgt cctgcggtgc    180

cctgggatcc gccgacatga atcccatcgt agtggtccac ggcggcggag ccggtcccat    240

ctccaaggat cggaaggagc gagtgcacca gggcatggtc agagccgcca ccgtgggcta    300

cggcatcctc cgggagggcg ggagcgccgt ggatgccgta gagggagctg tcgtcgccct    360

ggaagacgat cccgagttca acgcaggttg tgggtctgtc ttgaacacaa atggtgaggt    420

tgaaatggat gctagtatca tggatggaaa agacctgtct gcaggagcag tgtccgcagt    480

ccagtgtata gcaaatccca ttaaacttgc tcggcttgtc atggaaaaga cacctcattg    540

ctttctgact gaccaaggcg cagcgcagtt tgcagcagct atgggggttc cagagattcc    600

tggagaaaaa ctggtgacag agagaaacaa aaagcgcctg gaaaaagaga agcatgaaaa    660

aggtgctcag aaaacagatt gtcaaaaaaa cttgggaacc gtgggtgctg ttgccttgga    720

ctgcaaaggg aatgtagcct acgcaacctc cacaggcggt atcgttaata aaatggtcgg    780

ccgcgttggg gactcaccgt gtctaggagc tggaggttat gccgacnatg acatcggagc    840

cgtctcacca caggncatgg ggaagcatcc tgaaggtgaa ctggctagac tcacctgt      898


<210>  226
<211>  850
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (823)..(823)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (828)..(850)
<223>  n is a, c, g, or t

<400>  226
tagagagaat tactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg gacctacagc cgcccgggag aagatggctg    120

ccccagcagt gtccgggctc tcccggcagg tgcgatgctt cagtacctct gtggtcagac    180

catttgccaa gcttgtgagg cctcctgttc aggtatacgg tattgaaggt cgctatgcca    240

cagctcttta ttctgctgca tcaaaacaga ataagctgga gcaagtagaa aaggagttgt    300

tgagagtagc acaaatcctg aaggaaccca aagtggctgc ttctgttttg aatccctatg    360

tgaagcgttc cattaaagtg aaaagcctaa atgacatcac agcaaaagag aggttctctc    420

ccctcactac caacctgatc aatttgcttg ctgaaaatgg tcgattaagc aatacccaag    480

gagtcgtttc tgccttttct accatgatga gtgtccatcg cggagaggta ccttgcacag    540

tgacctctgc atctccttta gaagaagcca cactctctga attaaaaact gtcctcaaga    600

gcttcctaag tcaaggccaa gtattgaaat tggaggctaa gactgatccg tcaatcttgg    660

gtggaatgat tgtgcgcatt ggcgagaaat atgttgacat gtctgtcaag accaagattc    720

agaagctggg cagggctatg cgggagattg tctaaaagtg ttggttttct gccatcagtg    780

aaaattctta aacttggagc aacaataaaa agcttccaga acngatcnnn nnnnnnnnnn    840

nnnnnnnnnn                                                           850


<210>  227
<211>  1196
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (898)..(898)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (914)..(914)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (922)..(922)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (926)..(926)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (962)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (979)..(979)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (986)..(986)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (992)..(992)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1027)..(1028)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1044)..(1045)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1052)..(1052)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1077)..(1077)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1097)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1107)..(1107)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1115)..(1115)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1119)..(1119)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1126)..(1126)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1130)..(1130)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1132)..(1133)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1142)..(1142)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1145)..(1145)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1147)..(1147)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1153)..(1153)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1155)..(1155)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1159)..(1159)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1167)..(1167)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1175)..(1175)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1177)..(1177)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1183)..(1183)
<223>  n is a, c, g, or t

<400>  227
agagaaatta ctatgagagg atcgcatcac catcaccatc acggatccta tttaggtgac     60

actatagaat cgtcgaccca cgcgtccggc cgctgggcgc tcccgcggcg caggaggatg    120

ggctgcggcg ggagccgggc ggatgccatc gagccccgct actacgagag ctggacccgg    180

gagacagaat ccacctggct cacctacacc gactcggacg cgccgcccag cgccgccgcc    240

ccggacagcg gccccgaagc gggcggcctg cactcgggca tgctggaaga tggactgccc    300

tccaatggtg tgccccgatc tacagcccca ggtggaatac ccaacccaga gaagaagacg    360

aactgtgaga cccagtgccc aaatccccag agcctcagct caggccctct gacccagaaa    420

cagaatggcc ttcagaccac agaggctaaa agagatgcta agagaatgcc tgcaaaagaa    480

gtcaccatta atgtaacaga tagcatccaa cagatggaca gaagtcgaag aatcacaaag    540

aactgtgtca actagcagag agtccaagca gaagggcaga tggacttctt cagtgtcctt    600

cacggcactg gatcccatca aagaaccttg aagaagtggc tgccccttgc tggacctgaa    660

ttctactgag tccctggcaa gactgtctta cctggcagca aactgctgcc tgatttgttg    720

ggaccttctg agccttctac ttatcatgta aatgtattgg cacagtgctt acatatgtta    780

ataaactgca aatgtgcagt tcagtttgtc tctttgcaac tcctgtaata cggtctggtg    840

taaaaagtag tgagttaaag ctacaggtca gtttatgaaa cagaaaagta ggaatgcntt    900

ttctgggtga aaantcacac cnttantgct ataactctcc tgcccatgat agtgtattct    960

gntttcaggc aagcttatnc tttccntctt tncatttaaa nattgncatt acaatcttac   1020

caggttnntt taaancttgg tttnntccac tntaaacccc attttgaaaa ntcaagntac   1080

gggaaactcc ttgttnncct tgtttcntaa cttgnaagna aaaatngatn cnntttccat   1140

gnccnanccc tgncntggnt ttttttngaa ggttntntaa aanttacttt tttttt       1196


<210>  228
<211>  1410
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (10)..(12)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (812)..(812)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (906)..(906)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (942)..(942)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1327)..(1327)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1337)..(1339)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1343)..(1343)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1389)..(1389)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1405)..(1406)
<223>  n is a, c, g, or t

<400>  228
nggcccggcn nncgagagat actagagagg atcgcatcac catcaccatc acggtcgacc     60

cacgcgtccg ggctacattc ccattcctgt gctccatgaa ggcgctgaga accggcaggt    120

gcaccctttc catgtctatc cccagcctgg gatgcagcga ttccgaactg aggcggcagc    180

agcggcccct cagaggtccc agtcacctct gcggggcatg ccagaaacca ctcagccaga    240

taaacagtgt ggacaggtgg cagcggcggc ggcagcccag cccccagcct cccacggacc    300

tgagcggtcc cagtctccag ctgcctctga ctgctcatcc tcatcctcct cggccagcct    360

gccttcctcc ggcaggagca gcctgggcag tcaccagctc ccgcgggggt acatctccat    420

tccggtgata cacgagcaga acgttacccg gccagcagcc cagccctcct tccaccaagc    480

ccagaagacg cactacccag cgcagcaggg ggagtaccag acccaccagc ctgtgtacca    540

caagatccag ggggatgact gggagccccg gcccctgcgg gcggcatccc cgttcaggtc    600

atctgtccag ggtgcatcga gccgggaggg ctcaccagcc aggagcagca cgccactcca    660

ctccccctcg cccatccgtg tgcacaccgt ggtcgacagg cctcagccca tgacccatcg    720

agaaactgca cctgtttccc agcctgaaaa caaaccagaa agtaagccag gcccagttgg    780

accagaactc cctcctggac acatcccaat tncagtgatc cgcaaagagg tggattctaa    840

acctgtttcc cagaagcccc cacctccctc tgagaaggta gaggtgaaag ttccccctgc    900

tccagntcct tgtcctcctc cagccctggc ccttctgctg tnccctcttc ccccagagtg    960

tggctacaga agagagggca gcccccagca ctgcccctgc agaaactaca cctcaaaacc   1020

aggagagccg aagctccccc aaacatccag agtgctgaaa gtgaaagcat cctggaaaag   1080

gaacgggcct gagcaggtgg aaccacttga aggaaaaaac tgacaaaata ctgatgacca   1140

agatatttaa caagactgcg gcctgattca gggacccaag gacacccatg gtcccagcaa   1200

gaaaagggtc agaagtcaaa ctctggaaaa tgaagaaacc tggtcccggt agcccgcttg   1260

atcaccccac ctgaaaatcc ctgggcatgt aaaggggcgg acaaaggaaa aagggatgta   1320

atccccnaac ctcaaannnc ggnttcccga ggaagcctgc cccccctcga aaaacagatg   1380

gtgattgtnt aataattttt ttttnnggga                                    1410


<210>  229
<211>  1048
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (692)..(692)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (744)..(744)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (759)..(759)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (801)..(801)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (806)..(806)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (848)..(848)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (864)..(864)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (880)..(880)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (882)..(882)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (891)..(891)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (895)..(895)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (905)..(905)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (928)..(929)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (938)..(938)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (949)..(949)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (962)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (964)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (976)..(976)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (978)..(978)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (981)..(981)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (990)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (993)..(994)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(998)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1003)..(1003)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1022)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1028)..(1028)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1041)..(1041)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1048)..(1048)
<223>  n is a, c, g, or t

<400>  229
natatagaga aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgagtgggt gactgtgggt gacacgtccc    120

tgaggatatt taagtgggtt cctgtgacag acagcaagga gaaagaaaag tcaaaatcga    180

acagttcagc agcccgagaa cctaatggct ttccttctga tgcctcagcc aattcctctc    240

tccttcttga attccaggac gaaaacagca accagagttc cgtgtctgac gtctatcagc    300

ttaaggtgga cagcagcacc aactcaagcc ccagccccca gcagagtgag tccctgagcc    360

cagcacacac ctccgacttc cgcacggatg actcccagcc cccaacgctg ggccaggaga    420

tcctggagga gccctccctg ccctcctcgg aagttgctga tgaacctcct accctcacca    480

aggaagaacc agttccacta gagacacagg tcgttgagga agaggaagac tcaggtgccc    540

cgcccctgaa gcgcttctgt gtggaccaac ccacagtgcc gcagacggcg tcagaaagct    600

agcaccatcc cggccctccg cctcctggcc ctgcctctat ttattgcatt ctggttctgg    660

ccgcgccgcg ttgctggggt aagggcaagc antggggtca agagcctgca cacatgagcc    720

ttccgggctg gaaggctggc gtangacttg gggctgtanc atcatcttcc tgaccctggc    780

acctgtgtct acttgctccc naaaanagga gcgctcatgt ctttttttgc accccaagtt    840

ggctgganca tcggccaccc caanattcat ctgtgacctn cnaggcatta ntctntgctc    900

aaaantctct gggacggaac tgctggcnnc tttctgcnaa aaaaaaaana ttttgnaagg    960

cncnttctta aaaaanancg ngcctcaagn ttnnttnnac ttnaacggga aaatgtaaan   1020

nnccggantt tcccntaaga ntgggggn                                      1048


<210>  230
<211>  1149
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (859)..(859)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (875)..(875)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (899)..(899)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (909)..(909)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (943)..(943)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (957)..(957)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (964)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1010)..(1010)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1021)..(1021)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1026)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1031)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1037)..(1037)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1072)..(1072)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1081)..(1081)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1089)..(1089)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1093)..(1094)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1105)..(1105)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1117)..(1117)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1136)..(1137)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1143)..(1146)
<223>  n is a, c, g, or t

<400>  230
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgt ctcagacacc tttgcccctt cgccagacaa    120

aaccatcgac tgcgatgtca tcaccctgat gggcacaccg tctggcacag ctgagcccta    180

tgatggcacc aaggctcgcc tctatagcct gcagtcggac ccagcaacct actgtaatga    240

accagatggg cccccggaat tgtttgacgc ctggctttcc cagttctgct tggaggagaa    300

gaagggggag atctcagagc tccttgtagg cagcccctcc atccgggccc tctacaccaa    360

gatggttcca gcagctgttt cccattcaga attctggcat cggtatttct ataaagtcca    420

tcagttagag caggagcagg cccggaggga cgccctgaag cagcgggcgg aacagagcat    480

ctctgaagag cccggctggg aggaggagga agaggagctc atgggcattt cacccatatc    540

tccaaaagag gcaaaggttc ctgtggccaa aatttctaca ttccctgaag gagaacctgg    600

cccccagagc ccctgtgaag agaatctggt gacttcagtt gagcccccag cagaggtgac    660

tccatcagag agcagtgaga gcatctccct cgtgacacag atcgccaacc cggccactgc    720

acctgaggca cgagtgctac ccaaggacct gtcccaaaag ctgctagagg catccttgga    780

ggaacagggc ctggctgtgg atgtgggtga gactggaccc tcacccccta ttcactccaa    840

gcccctaacg cctgctggnc acaccggcgg cccanagccc aggcctccag ccagagtana    900

gactctgang gaggaggcgc ccacagactt acgggtgttt ganctgaact cggaaantgg    960

gaantctaca ccctccaaca atggaaanaa aggctcagcc cggacatcan tgaggactgg   1020

naaaanactt nacttgnaat gactgaaaag aagggcaaat ggcctttcca anggatgctc   1080

ngggactgna aanntaangg nagantggaa tgaggancca aggacacctc cccccnngga   1140

ttnnnnctc                                                           1149


<210>  231
<211>  816
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (690)..(690)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (723)..(723)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (732)..(732)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (739)..(739)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (760)..(760)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (792)..(793)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (796)..(796)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (800)..(800)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (805)..(805)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (807)..(807)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (815)..(815)
<223>  n is a, c, g, or t

<400>  231
tcttaangag ganaattaac tatgagagga tcgcatcacc atcaccatca cggatcctat     60

ttaggtgaca ctatagaatc gtcgacccac gcgtccggaa aaagatgtcc caatgctgcc    120

ccaaagccag agaagaaaga tggggtgtcc ttctgtgctg aacatgtccg taggaatgcc    180

ctggcacttc atgctcaaat gaagaagacc aacccagggc ctgtgggtga aacactcctg    240

tgccagctga gctcatatgc taagacagag ctggggtctc agactccaga aagtagtcgc    300

agtgaagcca gccgaatact agatgaagac agctggagtg atggggagca ggaacccatt    360

actgtggatc agacatggag aggtgaccct gacagtgaag ctgatagcat agacagtgat    420

caagaagatc ccctaaaaca tgctggtgtc tacacagcag aagaagtggc cctgattatg    480

cgtgaaaagc taattcgttt gcagtcgttg tatattgatc agtttaaacg acttcagcat    540

ctgctcaagg agaagaagcg ccgatactta cataatcgca aagtggaaca tgaagctcta    600

ggcagtagtc tcctgactgg cccagaaggg acttttggcc aaagaacgag agaacttaaa    660

gcgattaaaa tgtctgcgac gataccgccn gcgctatgga gtggaagcct tactgcatag    720

gcngttgaag gnaacggana atgctggcca cagatggtgn ttgcccaaca ggcccatacc    780

actcgttcca gnncanaggn gcttngncct tttgng                              816


<210>  232
<211>  1114
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (858)..(858)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (860)..(861)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (863)..(869)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (871)..(876)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (899)..(899)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (910)..(910)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (913)..(913)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (918)..(918)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (953)..(953)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (974)..(974)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (978)..(978)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1002)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1021)..(1021)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1038)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1043)..(1043)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1060)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1075)..(1075)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1103)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1107)..(1107)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<400>  232
aaatagagaa attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cgccgagacc gcggcggagc ctacggtccc    120

tgcagtgcct gctgctgagg aggccaccga agctcgggga cgcgaggagc cggcgtggcc    180

ctggaaagac gccccgatcc ggacgctggt gcagcgcatc caccagctgc aggctgagcg    240

cgcgcagggc ttccgccgac tggaggagtg gttggcgccg gtgcagggcc tgagagcctg    300

ggggcgcggc ctcagggtcc ccacatgccg cagaggccac cgccagtacc tgcgcagcgg    360

ccctgactac gacttcgcgc gctaccggag cacagtgcac ggggtgaccc aggccttcgc    420

cgccgcctcg cgggaggtgc tggcggtgga agcagagctg ggcgggcctc gcaggcagcc    480

gctgctcgcc ggccacgtgc gcagcctgca ggagctggag cagacgcggc tgggcacggt    540

ggccctgctg cagttgatgg agacgccaga gctggcgggg caggaggacg ctgtacggat    600

gcagcagctg aaaatgaagg taattaaaac catggaggcg atcagcgagg ttctccagga    660

ccttaggttt gatgcggaat ctgccgagtg atggcggctc cccagggatg cgccgaggga    720

gatgggaaac ggggcggatg gcgcccagcc cagccctaac tgccagctgg ctggggtcgc    780

gccccactgc gctgctgacc ttcctgcagt tccagacacc tcccacaata aagagctcct    840

cctctgtaaa aaaaaaanan nannnnnnna nnnnnnaaag ggcggccgct cccctatant    900

gagtcttatn aancttantt aactgaactt ggactccttg ttgaaaaatc cantaaatga    960

cctcaaaatc catnttgnat ttttttcaaa aacctcggtt nnccnccggg gcgttttttt   1020

ntttggtgaa aatccaanct aanctttggc aaaattttnn ggaacttaag gaacntaaaa   1080

tggaaaaaaa aatccttgga tnntccnccn ttta                               1114


<210>  233
<211>  438
<212>  DNA
<213>  Homo sapiens

<400>  233
gatagagaga ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gataaggagc agagtcctcc tggccttcga    120

ggcttcccat ttcgcactcc actaaagaaa aatcaaaatg cttctcttta caaagactgt    180

gtattcaata ccttaaacga acttgaagtg gagcttttga aatttgtgtc cgaagtgcag    240

aatcttaaag gtgccatggc aacaggcagt ggcagtaacc tcaagcttcg aaggtcagag    300

atgcctgcag atccatacca tgtcacaatc tgtaaaatat ggggagaaga aagctctagc    360

tgaatggatt tgtgtgtcag gagagaaaaa agttgagtgt tgacaaactg tatgcaaact    420

aataaaacta ttctgaag                                                  438


<210>  234
<211>  885
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (686)..(686)
<223>  n is a, c, g, or t

<400>  234
gatactatga gaggtcgcat caccatcacc atcacggatc ctatttaggt gacactatag     60

aatcgtcgac tctggacctt ggctgtcact cagttactca actaagaagc caggggagcc    120

aaaagtatgc cctccgcagt tttcagatgg cccgggtgat cttcaaccaa gacggctgct    180

cagtcttaca caggcattcc agggacaccc acttctaccc actggaggaa ggaagtacat    240

ctttggatga tgaaaagcca aacccacgac tgtcaaagga tattactcat ttcctctagc    300

atcataatgt aatgaaacac ctgtaactgg tgccgggtgg tgtgcatggt agtaatggag    360

gtgctgatgc catgaccatc actgttggtg gccacccaca tcccctaggg tcactggcca    420

gctctgtgtg cccaatccca attaagtgct ttgacgttaa acgctggcac ctgtgacctg    480

atattggagc cagtcatccc atatggagag ccagcaaggt ctgggagttc tccgtcctct    540

tggccaaggc cgctgactga ctgggctact agtcaaaagc ccatctccct tgcctcaagg    600

aatgacattc tctgacgagt aaattatgct ctagcactcc ctttcctcta gatcggcctg    660

aggctgggac attacatgaa atcacnccct tgctgggctt aatcccttta cctaccctcc    720

catttatata ctggtgtctc tgggagcctt tccttatgaa cctcttatat ctgagagaaa    780

taaaaaaaaa ctaaattagc ggccgctcct atagtgagtc gaataagctc aatatctgac    840

ttggactctg ttgatggatc catatgactc aaactcgtca gaatt                    885


<210>  235
<211>  962
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (5)..(6)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (853)..(853)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (860)..(860)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (882)..(882)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (888)..(888)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (900)..(900)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (904)..(904)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (909)..(909)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (913)..(913)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (915)..(915)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (917)..(917)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (920)..(920)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (922)..(922)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (925)..(925)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (928)..(928)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (936)..(936)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (943)..(943)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (948)..(949)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (952)..(952)
<223>  n is a, c, g, or t

<400>  235
ancanntaga gaaattacta tgagaggatc gcatcaccat caccatcacg gatcctattt     60

aggtgacact atagaatcgt cgacccacgc gtccgcccac gcgtccgaat ttctcttgga    120

caaatctgca gaaaaggctc ttgggaaggc agcatctcac attaaaagca ttaagaatgt    180

gacagagctg aagctttctg ataatcctgc ctgggaaggg gataaaggaa acactaaagg    240

tgacaagcac gatgacctcc agcgggcgcg tttcatctgc cccgttgtgg gcctggagat    300

gaacggccga cacaggttct gcttccttcg gtgctgcggc tgtgtgtttt ctgagcgagc    360

cttgaaagag ataaaagcgg aagtttgcca cacgtgtggg gctgccttcc aggaggatga    420

tgtcatcgtg ctcaatggca ccaaggagga tgtggacgtg ctgaagacaa ggatggagga    480

gagaaggctg agagcgaagc tggaaaagaa aacaaagaaa cccaaggcag cagagtctgt    540

ttcaaaacca gatgtcagtg aagaagcccc agggccatca aaagttaaga cagggaagcc    600

tgaagaagcc agccttgatt ctagagagaa gaaaaccaac ttggctccca aaagcacagc    660

aatgaatgag agctcttctg gaaaagctgg gaagcctccg tgtggagcca caaagaggtc    720

catcgctgac agtgaagaat cggaggccta caagtccctc tttaccactc acagctccgc    780

caagcgctcc aaggaggagt ctgccccact gggtcaccca cacgtcctac tgcttctgaa    840

gcccgcactg ccnccgctcn tgccccaaaa aggttgttta antttccncg taaggcaggn    900

cccntttgng ccncngnaan gnccngcngg ggggtncccc ccnaaaannt cnggggcaaa    960

aa                                                                   962


<210>  236
<211>  944
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (620)..(620)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (647)..(647)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (671)..(671)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (723)..(723)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (731)..(731)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (740)..(740)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (742)..(742)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (778)..(778)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (780)..(780)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (785)..(785)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (793)..(793)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (802)..(802)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (813)..(813)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (819)..(819)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (826)..(826)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (836)..(836)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (852)..(852)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (854)..(854)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (859)..(859)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (864)..(864)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (872)..(872)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (876)..(876)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (890)..(890)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (900)..(900)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (902)..(902)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (904)..(904)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (917)..(919)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (925)..(925)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (928)..(929)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (933)..(934)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (937)..(937)
<223>  n is a, c, g, or t

<400>  236
naattagaga aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgcgctgtt gcggcagctg gagacgaacc    120

agctggacat ggacgccacg ctggaggagc tgtcggtgca gcaggagacg gaggaccaga    180

actacggcat cttcctggag atgatggagg ctcgcagccg tggccatgcg tccccactgg    240

cggccaacgg gcagagccca tccccgggct cccagtcacc agtggtgcct gcaggcgctg    300

tgtccacggg gagctccagc cccggcacac cccagcccgc cccacagctg cccctcaatg    360

ctgccccacc atcctctgtg ccccctgtac caccctcaga ggccctgccc ccacctgcgt    420

gcccctcagc ccccgcccca cggcgcagca tcatctctag gctgtttggg acgtcacctg    480

ccaccgaggc agcccctcca cctccagagc cagtcccggc cgcacagggc ccagcaacgg    540

tccagagtgt ggaggacttt gttcctgacg accgcctgga ccgcagcttc ctggaagaca    600

caacccccgc cagggacgan aagaaggtgg gggccaaggc tgcccancag gacagcgaca    660

gtgatgggga ngccctgggc ggcaacccga tggtggcagg gttccaggac gatgtggacc    720

tcnaaaacca nccacgtggn antcccccgc tgccttgcag gccccgtccc aattcaanan    780

atcantcttt tcnagtgagg angaaacaaa aantggcanc tcccanaaaa ggcctngccc    840

caactcccca anantgctna aaanccaaaa ancaantggt cctccatacn actttcaaan    900

cnangaaggg ggaaaannnt cccanaanna acnnaanacc ccct                     944


<210>  237
<211>  867
<212>  DNA
<213>  Homo sapiens

<400>  237
tatgagaggt cgcatcacca tcaccatcac ggatcctatt taggtgacac tatagaatcg     60

tcgacccacg cgtccggccg agagaacttc tttcctgtga cagtggtgcc cacagcccct    120

gaccctgtgc cagctgactc tgtccagcgg cccagtgatg ctcacaccaa gcctcgccct    180

gcactagctg ccgccacaac tattatcacc tgccctccgt cagcatcagc ttccaccctg    240

gaccagtcca aggaccctgg gcctccccgg ccacacaggc ctgaagctac ccccagcatg    300

gcctctctgg gcccagaggg agaagagctg gcgagagtgg cagagggcac cagcttcccg    360

cctcaggagc cacggcacag tccgcaggtg aagatggccc ccacaagttc cccggcagag    420

ccacactgct ggccggcaga ggctgccctg ggcacaggcg ctgagcccac ctgcagccag    480

gctgccagct ccaaggcccc cagcagtggg agtgcccagc caccagaggg tcacccaggc    540

aagcctgagc ccagccgggc taagtcccgc cccctgccca acatgccaaa gctggtcatc    600

ccctccgccg ccaccaagtt cccccctgag atcaccgtca cgccacccac cccaaccctg    660

ctctccccca aaggcagcat ctcggaggag accaagcaga agctgaagtc agccatcctt    720

tctgcccagt ctgctgccaa cgtgaggaag gagagcctat gccagccagc cctggaggtc    780

ctggagacat ccagccagga gtcctcgctg gagagcgaga cagacgagga cgacgactac    840

atggacattt gaggggccac tgcagcc                                        867


<210>  238
<211>  1176
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (908)..(908)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (947)..(947)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (970)..(970)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (974)..(974)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (994)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (999)..(999)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1011)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1013)..(1013)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1028)..(1028)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1046)..(1046)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1048)..(1048)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1056)..(1056)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1060)..(1060)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1062)..(1062)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1066)..(1066)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1069)..(1069)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1076)..(1076)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1099)..(1099)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1109)..(1109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1111)..(1111)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1119)..(1119)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1125)..(1125)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1140)..(1140)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1150)..(1151)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1160)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1162)..(1162)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1173)..(1174)
<223>  n is a, c, g, or t

<400>  238
naattagaga aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgatcagcg gacacttact ctgtcctctt    120

ccaaagatgc caacattctt tcggagcaga tgagcctcaa agaagttctg gatgcgagtg    180

tgaaggaggt ggggtccagc tcctcagatg tctcgggaaa agagagcgtc cccgtggagg    240

agcctctgag gagcagggcc agcctcattg aagtggacct ctccgacctg aaggcccccg    300

acgaggatgg ggagctggta agcctcgatg gctcggcgga ccttgtcagc gaaggcgacc    360

agaagccggg ggtcggcttc ttcttcaagg atgaacagaa agcggaagat gagctcgcca    420

agaagcgggc ggccttcctc ctgaagcagc agcgcaaggc cgaggaggcc cgcgtgcgca    480

agcagcagct ggaagcggag gtggagctca agcgtgacga agcccggcgc aaagctgagg    540

aagaccgggt gcggaaggag gaggagaagg cgcggcgcga gctcatcaag caggagtacc    600

tgcggaggaa gcagcagcag atcctagagg agcaggggct cggcaagccc aagtcaaagc    660

cgaagaagcc gcggccgaag tcggtgcacc gggaagagtc gtgcagcgac tccggcacca    720

agtgctcctc cacccctgat aacttgagcc ggactcagtc aggctccagc ctgtccttgg    780

cctctgcggc gacgacagaa cccgagagcg ttcattccgg gggcacaccc tctcagcgag    840

tggaatcgat ggaagccctg cccatactga gccgtaaccc aagcaggagc acagaccgag    900

actggganac cgcgtcggcg gcatcttccc tggcctcagt ggccgantac acaggtccca    960

agctctttan ggancccagt antaattcaa acanncnant attcccaatg ncntatccca   1020

ttgctgcntg gctggaaaag tgaacnancc cccaanaatn cntatngang aactgnaaaa   1080

tgtgatgcca atccctacnt caactgttnc nggagctgnt gccanttcgg ggctttatgn   1140

tcttcctgan ntgagaaatn tnaaattcct ggnngg                             1176


<210>  239
<211>  1348
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (793)..(793)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (805)..(805)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1182)..(1182)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1198)..(1198)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1255)..(1255)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1262)..(1262)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1269)..(1270)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1274)..(1274)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1313)..(1313)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1341)..(1342)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1348)..(1348)
<223>  n is a, c, g, or t

<400>  239
nggatatact gacttaccta taaataggcg tatcacgagg ccctttcgtc ttcacctcga     60

gaaatcataa aaaatttatt tgctttgtga gcggataaca attataatag attcaattgt    120

gagcggataa caatttcaca cagaattcat taaagaggag aaattaacta tgagaggatc    180

gcatcaccat caccatcacg gtcgacccac gcgtccgggc tacatggcct tcctcaccta    240

tgatgaggtc caagagcgtc tgcaggcctg cagggacaag ccaggcagtt acatcttccg    300

gcccagctgt actcgcctgg ggcagtgggc catcggctat gtgagctcag atggcagcat    360

cctgcagacc atccctgcca acaaacccct gtcccaggtg ctcctggagg gacagaagga    420

cggcttctac ctctacccag atggaaagac ccacaaccca gacctgactg agctcggcca    480

ggcagaaccc cagcagcgca tccacgtgtc agaggagcag ctgcagctct actgggccat    540

ggactccaca tttgagctct gcaagatctg tgctgagagc aacaaggatg tgaagattga    600

gccgtgcggg cacctgctct gcagctgctg cctggctgcc tggcagcact cggacagcca    660

gacctgcccc ttctgccgct gcgagattaa gggctgggag gccgtgagta tctaccagtt    720

ccacggtcag gctactgctg aggactcagg gaacagcagt gaccaggaag gcagggagtt    780

ggagctgggg cangtgcccc tttcngctcc tccattgccc ccacggccag atctgccccc    840

caggaagccc agaacggccg cgatccgcat gcgagctcga ttacctgaac ctggactcct    900

gttgataaaa tcagtaatga ccctcaaact ccatctggat ttgttcaaaa accccggttg    960

gcccccgggc gttttttatt gggaaaaatc caactactta gggaaaattt ccggaactag   1020

gaaaccaaaa ggaaaaaaaa acccacgaaa ataccaccat gaaaaaaccc aaggcctcaa   1080

aaaaaaatta aaggatttcc acaaccatta agcacctaaa acagaccgta tacgaagatt   1140

cccgcccttt taacccgtaa aaaaacacac acaaattacc tnccctaacc ccattcancc   1200

acaaaaaaca gccccccaat ttcatacaca aaaaacgaaa cacgaataac ccacnacccc   1260

cntccacann actntaaaaa ccacaaatcc acaccgacaa aaaaaccacc cancacatac   1320

caaaacccca ctaaaaacga nnaaacan                                      1348


<210>  240
<211>  837
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (741)..(741)
<223>  n is a, c, g, or t

<400>  240
agatactatg agaggtcgca tcccatcacc atcacggatc ctatttaggt gacactatag     60

aatcgtcgac tctggacctt ggctgtcact cagttgagga ccctgacccc aagatggcgg    120

cgcccagcga agtggccgcg atagcccctg gcgaaggcga tggcggaggc ggcggctttg    180

gctcctggct ggacggacgg ttggaggcac tgggagtgga ccgagccgtt tatggagcct    240

acatcttggg tatcctgcag gaggaggagg aagaagagaa gctggacgct ctgcagggga    300

tcctctctgc tttcctggaa gaagattccc tccttaatat ctgcaaggag attgtggaac    360

gatggtcaga aactcagaat gttgtcacca aagtgaaaaa agaagatgaa gtacaggcca    420

ttgccaccct aattgagaag caggcacaaa tcgtagtaaa gccaaggatg gtgtcagaag    480

aggagaagca gagaaaagct gccctcctgg cccagtatgc tgatgtgaca gatgaagagg    540

aatatccttt ctggagtctc ggcaccattc cctaaagctc aagccagaca tatttgtggg    600

tttacagtga cctttggcaa gttgctaatc cccctctata gcttaatttt cccctctaaa    660

atggcagtaa tctatggccc tttgtggata tgcggagtga tattggatta gttgatactg    720

gacttatatt ttttcacaca ntatcattat attcctgaaa actttggtgt aaaacaataa    780

tgtcttaata gtcatttata ttatgctttc aaaaatacaa tatagctgta attcttt       837


<210>  241
<211>  1195
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (960)..(960)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (965)..(965)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (976)..(976)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1012)..(1012)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1023)..(1023)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1039)..(1039)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1073)..(1073)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1077)..(1077)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1083)..(1083)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1085)..(1085)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1087)..(1087)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1119)..(1119)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1128)..(1128)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1130)..(1130)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1136)..(1136)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1149)..(1149)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1152)..(1152)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1170)..(1170)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1175)..(1176)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1178)..(1178)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1183)..(1183)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1189)..(1190)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1192)..(1192)
<223>  n is a, c, g, or t

<400>  241
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg ggcagagcaa tggtggccag gctcgggctg    120

gggctgctgc tgctggcact gctcctaccc acgcagattt attccagtga aacaacaact    180

ggaacttcaa gtaactcctc ccagagtact tccaactctg ggttggcccc aaatccaact    240

aatgccacca ccaaggcggc tggtggtgcc ctgcagtcaa cagccagtct cttcgtggtc    300

tcactctctc ttctgcatct ctactcttaa gagactcagg ccaagaaacg tcttctaaat    360

ttccccatct tctaaaccca atccaaatgg cgtctggaag tccaatgtgg caaggaaaaa    420

caggtcttca tcgaatctac taattccaca ccttttattg acacagaaaa tgttgagaat    480

cccaaatttg attgatttga agaacatgtg agaggtttga ctagatgatg gatgccaata    540

ttaaatctgc tggagtttca tgtacaagat gaaggagagg caacatccaa aatagttaag    600

acatgatttc cttgaatgtg gcttgagaaa tatggacact taatactacc ttgaaaataa    660

gaatagaaat aaaggatggg attgtggaat ggagattcag ttttcatttg gttcattaat    720

tctataaggc cataaaacag gtaatataaa aagcttccat gattctattt atatgtacat    780

gagaaggaac ttccaggtgt tactgtaatt cctcaacgta ttgtttcgac agcactaatt    840

taatgccgat atactctaga tgaagtttta cattgttgag ctattgctgt tctcttggga    900

actgaactca ctttcctcct gaggctttgg atttgacatt gcatttgacc ttttatgtan    960

taatngacat gtgccnaggg caatgatgaa tgaaaatcta ccccccaaat cnagcatcct   1020

gancaactct tgatnatcnt attgagtcaa tggtaggcat ttcctatcac tgnttcnttc   1080

aananancac tacttntttt actnaacgga tccaaaaana aaattgcntn gacccnacta   1140

atttcaaang cntttaataa taatattttn aaaanncncc ttntccccnn gncgg        1195


<210>  242
<211>  1241
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (828)..(828)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (911)..(911)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (922)..(922)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (932)..(932)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (936)..(936)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (953)..(953)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (964)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (985)..(985)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (996)..(996)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1025)..(1025)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1028)..(1028)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1030)..(1030)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1044)..(1044)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1047)..(1047)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1060)..(1060)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1091)..(1091)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1094)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1102)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1120)..(1122)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1127)..(1127)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1129)..(1129)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1142)..(1142)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1147)..(1147)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1150)..(1150)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1163)..(1163)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1178)..(1178)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1191)..(1192)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1198)..(1198)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1201)..(1201)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1207)..(1207)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1215)..(1215)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1219)..(1219)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1223)..(1223)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1227)..(1228)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1230)..(1230)
<223>  n is a, c, g, or t

<400>  242
nttagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc ggccaaggca agatggtgga ctacagcgtg    120

tgggaccaca ttgaggtgtc tgatgatgaa gacgagacgc accccaacat cgacacggcc    180

agtctcttcc gctggcggca tcaggcccgg gtggaacgca tggagcagtt ccagaaggag    240

aaggaggaac tggacagggg ctgccgcgag tgcaagcgca aggtggccga gtgccagagg    300

aaactgaagg agctggaggt ggccgagggc ggcaaggcag agctggagcg cctgcaggcc    360

gaggcacagc agctgcgcaa ggaggagcgg agctgggagc agaagctgga ggagatgcgc    420

aagaaggaga agagcatgcc ctggaacgtg gacacgctca gcaaagacgg cttcagcaag    480

agcatggtaa ataccaagcc cgagaagacg gaggaggact cagaggaggt gagggagcag    540

aaacacaaga ccttcgtgga aaaatacgag aaacagatca agcactttgg catgcttcgc    600

cgctgggatg acagccaaaa gtacctgtca gacaacgtcc acctggtgtg cgaggagaca    660

gccaattacc tggtcatttg gtgcattgac ctagaggtgg aggagaaatg tgcactcatg    720

gagcaggtgg cccaccagac aatcgtcatg caatttatcc tggagctggc caagagccta    780

aaggtggacc cccgggcctg cttccggcag ttcttcacta agattaanac agccgatcgc    840

cagtacatgg agggcttcaa cgacgagctg gaagccttca aggagcgtgt gcggggccgt    900

gccaagctgc ncatcgagaa gncatgaagg antacnagga ggaggaccgc aanaagcggc    960

tcgncccggc ggcctgnacc cgtcnaggtc tacaantcct tccctgagaa ctccaaaatg   1020

cttcnatntn aagacttgca aatnctncag aaccccttcn caaaatggac cccccgacca   1080

aattacccat ncancctnct tnatttggcc ttggtcccan nnttagncnc cagccaagag   1140

gnaaaangcn gtctgggacc ttntgaactt ttccaaangg caaaaaagat nnttttantt   1200

nccattnccc ccctntttng ccntttnncn tttaaaaaaa a                       1241


<210>  243
<211>  865
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (753)..(753)
<223>  n is a, c, g, or t

<400>  243
agagatacta tgagaggtcg catcaccatc accatcacgg atcctattta ggtgacacta     60

tagaatcgtc gactctggac cttggctgtc actcagttag tgttgtgatg cagccgaaaa    120

gaaaacattt tattaaggat attcgtcatc ttcctgtgaa cagtaaggag tcccttgcaa    180

aagaagaaag ccaaatacca gtggatgaag tgtttttcca caggtattat aaaaaagttg    240

ctgttaaaga gaaacaaaaa cgggatgcag atgaagaaag tatagaagac gtggatgatg    300

aagaatttga agagctgatt gacacatttg aagatgataa ctgtttcagc tctggaaagg    360

atgatatgga ttttgctgga aacgtgaaaa agagaacaaa aggagctaag gataacacat    420

tagatgaaga ttcagaaggt agtgatgatg aacttggtaa cctggatgac gatgaagttt    480

ctttaggaag tatggatgat gaagaatttg ctgaagttga tgaagatgga ggaacattca    540

tggatgtgtt agatgatgaa agtgagagcg ttccagaact tgaagtccac tccaaagtca    600

gtactaagaa aagcaagaga aaaggtacag atgattttga ctttgctggc tcatttcaag    660

ggccaagaaa aaagaaaaga aacttaaatg attccagcct atttgtatct gctgaagagt    720

ttggccatct attggatgaa aatatgggat ccnagtttga taacattggc atgaatgcca    780

tggctaaaca agataatgca gtctcaacag cttaaatggg aggctgacgt gatgactggc    840

taccacagag atgcaaagta tctca                                          865


<210>  244
<211>  978
<212>  DNA
<213>  Homo sapiens

<400>  244
atgagaggtc gcatcaccat caccatcacg gatcctattt aggtgacact atagaatcgt     60

cgacccacgc gtccgcttcg cggctgctca agatgaaccg actcttcggg aaagcgaaac    120

ccaaggctcc gccgcccagc ctgactgact gcattggcac ggtggacagt agagcagaat    180

ccattgacaa gaagatttct cgattggatg ctgagctagt gaagtataag gatcagatca    240

agaagatgag agagggtcct gcaaagaata tggtcaagca gaaagccttg cgagttttaa    300

agcaaaagag gatgtatgag cagcagcggg acaatcttgc ccaacagtca ttcaacatgg    360

aacaagccaa ttataccatc cagtctttga aggacaccaa gaccacggtt gatgctatga    420

aactgggagt aaaggaaatg aagaaggcat acaagcaagt gaagatcgac cagattgagg    480

atttacaaga ccagctagag gatatgatgg aagatgcaaa tgaaatccaa gaagcactga    540

gtcgcagtta tggcacccca gaactggatg aagatgattt agaagcagag ttggatgcac    600

taggtgatga gcttctggct gatgaagaca gttcttattt ggatgaggca gcatctgcac    660

ctgcaattcc agaaggtgtt cccactgata caaaaaacaa ggatggagtt ctggtggatg    720

aatttggatt gccacagatc cctgcttcat agatttgcat cattcaagca tatcttgtaa    780

aacaaacaca tattatggga ctaggaaata tttatctttc caaatttgcc ataacagatt    840

taggtttctt tcctttcttt gaaggaaagt ttaattacat tgctctttta ttttttccat    900

taagagactc attgcttggg aaatgctttc ttcgtactaa aatttgattc cctttttttc    960

ttatgaaaaa cgaactca                                                  978


<210>  245
<211>  988
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (579)..(579)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (788)..(789)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (791)..(791)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (795)..(795)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (801)..(802)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (804)..(805)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (809)..(809)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (811)..(811)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (817)..(817)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (872)..(872)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (901)..(901)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (904)..(905)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (913)..(913)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (916)..(917)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (934)..(935)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (941)..(941)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (944)..(944)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (971)..(973)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (976)..(976)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (985)..(985)
<223>  n is a, c, g, or t

<400>  245
nnantagaga aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgcacagct gtacagcacc cgtgaaaagc    120

aacagctggc cagcctggtg ggcacgatgc tcgcttacag cctgacctac cgccaggagc    180

gcacgcccga tggccagtac atctacaggc tggagccgaa cgtggaggaa ctctgccgct    240

tccctgagct gcctgcccgc aagcccctca cctaccagac gaagcagctc atcgcccgcg    300

agatcgaggt ggagaagatg cggcgggcgg aggcttctgc ccgggtagag aacagccccc    360

aggtggatgg gagcccccca gggctcgagg gtctgctggg gggcattggg gagaaagggg    420

tgcaccgacc tgccccacgc aaccatgagc agcggctgga gcacatcatg aggcgagcgg    480

cccgggagga acagcctgag aaggacttct ttggacgtgt ggtcgtcagg agcacagcag    540

tcccgagtgc aggggacacg gccccggagc aggactcant ggagcggcgc atgggcacag    600

cggtgggcag gagcgaggtc tggttccgct tcaacgaggg tgtctccaac gccgtgcggc    660

gcagcctgta catcagggac ttgctctagt tctctgagcc gcggacatgc cctcgcattg    720

cttcccgcag agtgcagaga caggaagctg gagatgtctt tataaagtca cacctttaca    780

gactgttnna naaantttta nnannttana ntaatantaa aagggcggcc cgctccctat    840

agtgagtcgt attaagcttt aattagcttg ancttggaat tcctgttgat aaatcccagt    900

natnnacctc canaanntcc atctgggatt tttnnaaaac nctnggtttg cccccggggg    960

gttttttttt nnnganaatc ccaancta                                       988


<210>  246
<211>  986
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (881)..(881)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (899)..(899)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (972)..(972)
<223>  n is a, c, g, or t

<400>  246
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg tctcatgaag ccgctggtcg tgttcgtcct    120

cggcggcccc ggcgccggca aggggaccca gtgcgcccgc atcgtcgaga aatatggcta    180

cacacacctt tctgcaggag agctgcttcg tgatgaaagg aagaacccag attcacagta    240

tggtgaactt attgaaaagt acattaaaga aggaaagatt gtaccagttg agataaccat    300

cagtttatta aagagggaaa tggatcagac aatggctgcc aatgctcaga agaataaatt    360

cttgattgat gggtttccaa gaaatcaaga caaccttcaa ggatggaaca agaccatgga    420

tgggaaggca gatgtatctt tcgttctctt ttttgactgt aataatgaga tttgtattga    480

acgatgtctt gagaggggaa agagtagtgg taggagtgat gacaacagag agagcttgga    540

aaagagaatt cagacctacc ttcagtcaac aaagccaatt attgacttat atgaagaaat    600

ggggaaagtc aagaaaatag atgcttctaa atctgttgat gaagtttttg atgaagttgt    660

gcagattttt gacaaggaag gctaattcta aacctgaaag catccttgaa atcatgcttg    720

aatattgctt tgatagctgc tatcatgacc cctttttaag gcaattctaa tctttcataa    780

ctacatctca attagtggct ggaaagtaca tggtaaaaca aagtaaattt ttttatgttc    840

ttttttttgg ccacaggagt agacagtgaa ttcaggttta ncttcacctt agttatggng    900

ctcaccaaac gaagggtatc agctattttt ttttaaattc aaaaaaaaat atccctttta    960

tagttggggc cntctgggag caaaac                                         986


<210>  247
<211>  1177
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (866)..(866)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (992)..(992)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (994)..(994)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1011)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1016)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1027)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1029)..(1029)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1048)..(1048)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1050)..(1050)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1057)..(1057)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1068)..(1068)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1075)..(1075)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1077)..(1077)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1081)..(1081)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1087)..(1087)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1095)..(1095)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1097)..(1097)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1102)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1127)..(1128)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1131)..(1131)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1133)..(1133)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1152)..(1152)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1156)..(1156)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1170)..(1170)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1176)..(1176)
<223>  n is a, c, g, or t

<400>  247
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc tgacatcatc cagggcaagc tggaccagcg    120

aaaccagctg ctggaagtgg atttctgcat tggccgtgac atccgaaaga aggatatcaa    180

taatattgtc aagaccctgc atgaatggtg tgatggctgt gaagcagttc tactgggcat    240

cgagcagcaa gttctgagag ccaaccagta caaagagaac cacaaccgaa ctcagcagca    300

ggtagaagca gaggttacca acatcaagaa gacactcaaa gccaccgcat cctcctcggc    360

tcaggagatg gagcagcagc tggctgaacg ggagtgtccc cctcacgctg agcagaggca    420

gcccaccaag aagatgtcca aagtgaaagg tctggtctcc agccgccact agggccggct    480

ggggcagctg gcactcacca ggcctgggtc aggtggggag gggacaccaa gggcccattt    540

cctcccctct ctacctgcag tgagttccag acctgcccgt cccctcacca gcgcctcccc    600

accctgttgg tactgttcca gaaaaactgt tactccccct cacccactcc ctccttcccc    660

agttgttccc ttcagactca ggggctccac caatgccatc ccaaaacagg gtcagacact    720

gcccagcttc cctccaggag gttcttgtct ctgtgtaagg gcttgtctcc ctcccagttt    780

ttcttttgct ccacgtcatt ttgtcaggct ggttataagc cggaggcagc tttaaccagc    840

ccccagggat gattgtttga aaggangccc cttccccttg tgaaggaggg ggcactcctc    900

tccagcccct ggtaccacag tcctcacgaa tggtgcagtg atttctagcc aggcgtcaag    960

atgcgctgct tttcctctcc tgcctcatcc cntngttggc agctccattt nagccntggn   1020

aagganntna tttttgggct tttttttntn aaacccncgg gttttttncc ccttnanccc   1080

ncctccnatt tccantnttt tnaaagggcn ggggtgaaaa accctgnnat ntnaaaaaaa   1140

aaaaaagggg gnttgntttt tttgggtggn aaaaang                            1177


<210>  248
<211>  586
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (5)..(7)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (345)..(345)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (361)..(361)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (429)..(429)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (475)..(475)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (496)..(496)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (505)..(505)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (520)..(520)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (531)..(531)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (534)..(534)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (538)..(539)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (541)..(541)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (545)..(545)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (552)..(553)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (558)..(558)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (562)..(562)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (568)..(568)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (570)..(570)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (572)..(572)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (581)..(581)
<223>  n is a, c, g, or t

<400>  248
aaaannnagg anaataacta tgagaggatc gcatcaccat caccatcacg gatcctattt     60

aggtgacact atagaatcgt cgacccacgc gtccggcgcc ctgtcctccg tcggctctgc    120

gggctcccgg gcctacagcg gcctgcggca gaaatgcccc tccgggctag gagcgacggc    180

gccggcccgc tatactcgca ccacctcccc acctccccgc tgcagaaagc gctgttggcc    240

gccggctccg cggcgatggc gctctataac ccctaccgcc acgacatggt cgcagttcta    300

ggggagacca caggacaccg caccctgaag gtcctcaggg accanatgag gagggatcca    360

nagggtgccc agatcctgca ggagcgtccc cggatttcga catccaccct cgacctgggc    420

aagctccana gcctgccgga aggctccctc ggtcgcgagt atctccgttt cctgnatgtg    480

aacagggtct ccccanacac ccgancaccc acccgcttcn tggatgatga nganctanng    540

natgngattc annggtancg gnaggtgnan anatgcttca naccct                   586


<210>  249
<211>  1047
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (909)..(909)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (934)..(934)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (940)..(940)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (944)..(944)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (964)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (976)..(976)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (999)..(999)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1007)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1017)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1028)..(1028)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1034)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1047)..(1047)
<223>  n is a, c, g, or t

<400>  249
agaaattaac natgagagga tcgcatcacc atcaccatca cggatcctat ttaggtgaca     60

ctatagaatc gtcgacccac gcgtccgaga cagagcgcgg acgccgcagg aggcagtgcc    120

tggaccccag ctgcccagga gagacggagc ccgtggctgg tgaggccgca gagcagggcc    180

aggccgggcc ctgcccgcaa ggacgaccaa acccctcacc ggcccctggg ccccagagcc    240

caccaggctc tcctgctggc cccaccatga cttcagagtc gacgtcaccc ccagttgtgc    300

ccccgctcca ctcccccaag tccccagtct ggcccacctt ccccttccac agggagggca    360

gcagggtctg ggagcggggt ggtgtcccac ctcgggacct acccagccct ctgcccacca    420

agcggaccag gacctattca gcgacagccc gggcctcagc tggccccgtg ttcaagggcg    480

tctgtaagca gttctcacgc tcacagggcc atggcttcat cacccccgag aacgggtccg    540

aggacatctt cgtacatgtg tctgacatcg agggggagta cgtgccagtg gagggcgacg    600

aggtgaccta caagatgtgc cctatccctc ccaagaacca gaagttccag gccgtggagg    660

tggtgctcac tcagctggcc ccccacactc cccacgagac gtggtctggc caggtcgtgg    720

gctcctaggc tgagtggttc acaggccagc tggccggggg ttggggagcc acacagggtg    780

aacgggcagc agccggctcc atgccccact gccctggctg atgagtcctt cggtggcctc    840

agtgtgcacg tctgtctgtc cgtctgtgct tgtggctatg aacgtgtgcc tccacccacc    900

ccacgaccng tgactactgt gcaagctggc aagnaggtan gtgnaggcaa gccacnaaac    960

tggnttcggc tgtcantggc tntntcttcc ctccttggng aaaaannaga accgntnncn   1020

tttgttancg tccnngggan tgaattn                                       1047


<210>  250
<211>  877
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (658)..(658)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (728)..(728)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (738)..(738)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (745)..(745)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (752)..(752)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (768)..(768)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (781)..(781)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (800)..(800)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (802)..(802)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (808)..(808)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (834)..(834)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (836)..(836)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (839)..(839)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (868)..(868)
<223>  n is a, c, g, or t

<400>  250
ttattaaaga ggagaaataa ctatgagagg atcgcatacc atcaccatca cggatcctat     60

ttaggtgaca ctatagaatc gtcgacccac gcgtccgtcc aaaacaagtg gctgcggccg    120

tcgcccagga gtcatcggac gccagaatct ggccgggttc tgagcttgtt ccgcctccct    180

cccccgggaa tggcgctatc cgggtcgacc ccggccccgt gctgggagga ggatgagtgc    240

ctggactact acgggatgct gtcgcttcac cgtatgttcg aggtggtggg cgggcaactg    300

accgagtgcg agctggagct cctggccttt ctgctggatg aggctcctgg cgccgccgga    360

ggcttagccc gggcccgcag cggcctagag ctcctgctgg agctggagcg ccgcgggcag    420

tgcgacgaga gcaacctgcg gctgctgggg caactcctgc gcgtgctggc ccgccacgac    480

ctgctgccgc acctggcgcg caagcggcgc cggccagtgt ctccagaacg ctatagctat    540

ggcacctcca gctcttcaaa gaggacagag ggtagctgcc gtcgccgtcg gcagtcaagc    600

agttctgcaa attctcagca gggtcagtgg gagacaggct cccccccaac caagcggnag    660

cggcggagtc ggggccggcc cagtggtggt gccaaacggc ggcggaaagg ggccccagcc    720

gcacccanca gcagtcanag cccgncagac cnttctttga agcaaagnga cctgggacat    780

ncggcttcgg gttcgaacan antactgnga gcatgggcca accttggaaa aggngnggna    840

ttccgggggg cccaggcgct ggggcggnaa ttggacg                             877


<210>  251
<211>  1275
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (827)..(827)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (889)..(889)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (932)..(932)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (951)..(951)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (961)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (975)..(975)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (980)..(980)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1032)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1036)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1044)..(1044)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1069)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1083)..(1083)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1103)..(1103)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1124)..(1124)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1126)..(1126)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1130)..(1132)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1170)..(1170)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1185)..(1185)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1188)..(1188)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1192)..(1192)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1209)..(1209)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1218)..(1218)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1239)..(1239)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1247)..(1247)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1249)..(1249)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1254)..(1254)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1258)..(1258)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1274)..(1275)
<223>  n is a, c, g, or t

<400>  251
tagagaaaat tactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg gccgccgccg gggcatagag gagcatcgac    120

tgtacgaaat ggccaacctt cggcgccagt tcaaggagct gttggaggac cacgggctgc    180

tggctggggc ccaggccgcg caggtagggg acagctacag tcggttgcag cagcgccggg    240

agcgccgggc cctgcaccag ctgaaacgcc agcacgagga gggcgcgggg cgcaggcgca    300

aggtgctgcg gctgcaggag gagcaggacg gcggctccag tgacgaggac agggctggcc    360

cagccccccc aggggccagt gatggcgtgg acatccagga tgtgaagttc aagcttcggc    420

atgacctggc gcagctgcag gccgctgcca gctcagccca ggacctgagc cgcgagcagc    480

tggctctgct gaagctggtg ctgggccggg gcctgtaccc acagctggcc gtccccgacg    540

ccttcaacag cagccgaaag gactcagacc agattttcca cacgcaggcc aagcagggcg    600

ccgtgctgca ccccacctgc gtcttcgctg gcagccccga ggtgctgcac gcacaggagc    660

tggaggccag caactgcgac ggaagccgag gcatggctgc gtgctgggag tcacattcag    720

atttggctga ccttcttgtc tgagccaggc caccaaagcc atgccacgac aaggacaaga    780

tgagcagcaa acaccagctc ctcagcttcg tgtccctgct ggagacnaac aagccgtacc    840

tggtgaactg cgtccgcatc cctgcccctc cagtcctcct gctttttanc cggtctttga    900

aaccaatggt gactgctccc gcctggtggc cnatggctgg ctgaactgca nctacaaaaa    960

nngaaagtgc catcnantcn tggngggntt cctgcggttc gtgcccgctg gaaaannncc   1020

ttgaaccgga antggncaac aagncccaac accattggaa gaaaaagann aaaaaaaccc   1080

cantcacccc aaagaagngg ccncccttga aaaaggaaat tctngnattn nnggattcca   1140

aaatttttaa gcctccgggg gttcaaaggn ttaaaatcca aaaanttntt tnggaaccca   1200

aaaatccanc cccccccntt tttttgggtt ttttggaant tcccctntnc cccncccnaa   1260

aagggggtaa aaann                                                    1275


<210>  252
<211>  1214
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (902)..(902)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (928)..(928)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (950)..(950)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (965)..(965)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (989)..(989)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1004)..(1004)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1018)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1022)..(1022)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1048)..(1048)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1050)..(1050)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1061)..(1061)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1066)..(1066)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1068)..(1068)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1085)..(1085)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1087)..(1087)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1117)..(1117)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1119)..(1119)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1122)..(1122)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1130)..(1130)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1132)..(1132)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1137)..(1137)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1148)..(1148)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1155)..(1155)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1162)..(1162)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1181)..(1181)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1185)..(1185)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1199)..(1199)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1208)..(1209)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1212)..(1212)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1214)..(1214)
<223>  n is a, c, g, or t

<400>  252
attagagaga ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gagacgctgc aaattgcttg tggacggtgt    120

aggccgctgc aggccaccat gaaccggctt ccggatgact acgaccccta cgcggttgaa    180

gagcctagcg acgaggagcc ggctttgagc agctctgagg atgaagtgga tgtgctttta    240

catggaactc ctgaccaaaa acgaaaactc atcagagaat gtcttaccgg agaaagtgaa    300

tcatctagtg aagatgaatt tgaaaaggag atggaagctg aattaaattc taccatgaaa    360

acaatggagg acaagttatc ctctctggga actggatctt cctcaggaaa tggaaaagtt    420

gcaacagctc cgacaaggta ctacgatgat atatattttg attctgattc cgaggatgaa    480

gacagagcag tacaggtgac caagaaaaaa aagaagaaac aacacaagat tccaacaaat    540

gacgaattac tgtatgatcc tgaaaaagat aacagagatc aggcctgggt tgatgcacag    600

agaaggggtt accatggttt gggaccacag agatcacgtc aacaacagcc tgttccaaat    660

agtgatgctg tcttgaattg tcctgcctgc atgaccacac tttgccttga ttgccaaagg    720

catgaatcat acaaaactca atatagagca atgtttgtaa tgaattgttc tattaacaaa    780

gaggaggttc taagatataa agcctcagag aacaggaaga aaaggcgggt ccataagaag    840

atgaggtcta accgggaaga tgctgctgag aaggcagaga cagatgtgga aaaaatctat    900

cncccagtca tgtgcactga atgttccnct gaagtggcag tctacgacan ggatgaagtc    960

tttcnttttt cccatgtttt ancaagccnt tcctaaacag cccnactggc atttattncc   1020

cnatactgta tataaggcaa attggacngn tactttccnc ntgccngntc naatccttca   1080

gggantngag gaaccntgtt ncctttttaa ggaaaanant gncaccttcn tnctccntta   1140

atcccccncc ccccnttttt tncttgattt cccccctatg ngggnacgaa atccttcgnt   1200

ttgaaaannt tngn                                                     1214


<210>  253
<211>  1090
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (753)..(753)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (795)..(795)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (815)..(815)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (818)..(818)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (844)..(844)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (851)..(851)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (868)..(868)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (876)..(876)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (882)..(882)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (915)..(915)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (918)..(918)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (920)..(920)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (922)..(922)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (941)..(941)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (948)..(948)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (951)..(951)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (955)..(955)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (964)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (967)..(967)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (979)..(979)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(985)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (993)..(993)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (995)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1004)..(1004)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1009)..(1009)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1012)..(1012)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1028)..(1028)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1032)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1045)..(1045)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1050)..(1050)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1052)..(1052)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1057)..(1057)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1069)..(1069)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1076)..(1076)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1080)..(1080)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1089)..(1089)
<223>  n is a, c, g, or t

<400>  253
nagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg ccctgccggc cccgcgggtc atggaggagt    120

tccggcgctc ctacagccgc ctgtgcaggg agagtggggc cgagccccag gaggctgtcc    180

tgcagcagct gcaccagctt cccaggggcc ggctggacct ggccacgcaa agcctgacgg    240

tggagacctg cagggccctg ggcaagctgc tgccgaggga gacgctgtgc acggagctgg    300

tcctgagtga ctgcatgctc agcgaggaag gggccacact gctgctccga ggcctgtgtg    360

ccaacaccgt gctgcgcttt ctggacttaa agggcaacaa ccttcgggct gcaggggccg    420

aggctctggg aaaactcctc caacagaaca agtccattca gagcctcacg ctggagtgga    480

acagcctggg cacgtgggac gatgccttcg ccaccttctg cgggggcctg gcggccaacg    540

gcgccctgca gcggctggac ctccgcaaca accagatcag tcacaagggc gcggaggagc    600

tggccctagc cctgaagggc aacaccaccc tccagcagct ggacctgcgc tggaataacg    660

ttggcctcct ggggggccgg gccctcatga actgtctccc cagcaacaga accctgtgga    720

gactggacct ggctgggaac aacatccctg ganacgtcct cagagccgtg gagcaagcca    780

tgggccacag ccagnaccgg ctcaccacct tccanganaa ccaagcccgc actcacgtcc    840

tcancaagga ngtccagcac ctccgggnag gaaaantcca ancagttcct cgacttgatg    900

gaaactattg ataancancn anaaaaaatg gccaaaaaca ncagggcntc ngcancccgt    960

gtanggnaac ttcaggaanc cctnnaatga aangnantcc atcntnaang cnttnaaggn   1020

caaactgnaa antaaaaaaa agccnccctn gnttttntcg aaacaaaang nccaanaacn   1080

tgggggaant                                                          1090


<210>  254
<211>  548
<212>  DNA
<213>  Homo sapiens

<400>  254
tgagaggtcg catcaccatc accatcacgg atcctattta ggtgacacta tagaatcgtc     60

gacccacgcg tccgcccacg cgtccgctcg cctggccacc gggccacggc cccacagacc    120

cagtgacaat gaggaggagg acaaggaggc ggcacagctg cgggaggagc ggctacggca    180

gtacgcggag aagaaggcca agaagcctgc actggtggcc aagtcctcca tcctgctgga    240

tgtcaagcct tgggatgatg agacggacat ggctcagctg gaggcctgtg tgcgctctat    300

ccagctggac gggctggtct ggggggcttc caagctggtg cccgtgggct acggtatccg    360

gaagctacag attcagtgtg tggtggagga cgacaaggtg gggacagact tgctggagga    420

ggagatcacc aagtttgagg agcacgtgca gagtgtcgat atcgcagctt tcaacaagat    480

ctgaagcctg agtgtgtgta cgtgcgcgcg tgcgtgaggc cctgccacga ttaaagactg    540

agaccggc                                                             548


<210>  255
<211>  1163
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (5)..(5)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (829)..(829)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (845)..(845)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (905)..(905)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (943)..(943)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (969)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (971)..(971)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (974)..(974)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (994)..(994)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (996)..(996)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1008)..(1009)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1017)..(1017)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1022)..(1022)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1027)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1031)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1043)..(1043)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1049)..(1050)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1073)..(1073)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1076)..(1076)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1081)..(1081)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1085)..(1085)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1107)..(1107)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1122)..(1122)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1127)..(1127)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1129)..(1129)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1132)..(1132)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1134)..(1137)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1147)..(1147)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1160)
<223>  n is a, c, g, or t

<400>  255
agagnaatta ctatgagagg atcgcatcac catcaccatc acggatccta tttaggtgac     60

actatagaat cgtcgaccca cgcgtccgcg agagcaaacc cagtgactca cctccgccgt    120

gctaactcct cgctagctct ccctctcaca cacgctcaca cccggctcga gatggcggcg    180

gcggcggcgg cggcggggga ctcggactcc tgggacgccg acgctttctc cgtggaagac    240

ccagtgcgga aggtgggggg cggcggcact gccggcgggg accgctggga aggcgaggac    300

gaggacgagg acgtcaagga taactgggat gacgatgatg atgaaaaaaa agaggaagca    360

gaagtaaaac cagaggtaaa aatttcagaa aagaaaaaaa tagcagagaa gataaaagag    420

aaagaacggc aacagaagaa aaggcaagaa gaaattaaaa agaggttaga agaacccgaa    480

gaacctaaag tgctaacacc agaagaacaa ttagcagata aactgcggct aaagaaatta    540

caggaagagt cagacctcga attagcaaag gaaacttttg gtgttaataa tgcagtttat    600

ggaatagatg ctatgaaccc atcttcaaga gatgacttta cagagtttgg aaagttacta    660

aaagataaaa ttacacaata tgaaaagtca ctatattatg ccagtttttt ggaagtctta    720

gttcgagatg tgtgtatttc attggaaatt gatgacttga aaaaaattac caattcactg    780

actgtgcttt gcagtgaaaa acagaagcaa gaaaagcaaa gcaaagccna aaagaagaag    840

aaagntgtgg ttcctggagg gggattaaaa gccaccatga aagatgatct ggcaaattat    900

ggtgnttatg atggaggatt tgtacaagac tatgaagact tcntgtgaca ttttatcttt    960

tcttggggnc ntcntttatg ttgcccccaa tccntngaac ttgtagcnna actttcnttt   1020

tntttnngtt ntgccaaatg ctncaatcnn aagtgcagta tctttttggn tgnttnttta   1080

ncccnttgaa ctttaggngc ctattgncca attgaaggaa cnttggntnt tntnnnncca   1140

ggggttnaaa ttgggaaacn taa                                           1163


<210>  256
<211>  920
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (739)..(739)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (759)..(759)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (765)..(765)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (767)..(767)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (773)..(773)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (782)..(783)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (795)..(795)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (802)..(803)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (818)..(818)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (836)..(836)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (868)..(868)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (873)..(874)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (876)..(876)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (885)..(885)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (887)..(887)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (889)..(891)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (897)..(898)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (901)..(901)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (910)..(910)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (914)..(914)
<223>  n is a, c, g, or t

<400>  256
caatagagag aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccggccgccg ccgccgccgc cgccgggtcg    120

cccctggccc ggcgcgcccg tccccggcag cgacaatgag tgaacagagt atctgccaag    180

cccgggcttc cgtgatggtc tacgatgaca ccagtaagaa atgggtacca atcaaacctg    240

gccagcaggg attcagccgg atcaacatct accacaacac tgccagcaac accttcagag    300

tcgttggagt caagttgcag gatcagcagg ttgtgatcaa ttattcaatc gtgaaagggc    360

tgaagtacaa tcaggccacg ccaaccttcc accagtggcg agatgcccgc caggtctacg    420

gcttaaactt tgcaagtaaa gaagaggcaa ccacgttctc caatgcaatg ctgtttgccc    480

tgaacatcat gaattcccaa gaaggaggcc cctccagcca gcgtcaggtg cagaatggcc    540

cctctcctga tgagatggac atccagagaa gacaagtgat ggagcagcac cagcagcagc    600

gtcaggaatc tctagaaaga agaacctcgg ccacagggcc catcctccca ccaggacatc    660

cttcatctgc agccagcgcc cccgtctcat gtagtgggcc tccaccgccc cccccacccc    720

cagtcccacc tccacccant ggggctaccc cactccccna ccccnantgc canccggagg    780

annccagggg tccanccacg annagagctc catgtcanga ctggccgctg ccatanctgg    840

ggccaactga aaaaattcaa acggccanaa aanncntctg gaagntncnn ntcccanngg    900

nacttcaaan tccnatgcca                                                920


<210>  257
<211>  1129
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (700)..(700)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (785)..(785)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (802)..(802)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (811)..(811)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (815)..(815)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (823)..(824)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (846)..(846)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (854)..(854)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (877)..(877)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (887)..(887)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (891)..(891)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (901)..(901)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (908)..(908)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (919)..(919)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (922)..(922)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (944)..(944)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (958)..(958)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (961)..(961)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (970)..(970)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (978)..(978)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (980)..(980)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (999)..(999)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1011)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1017)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1027)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1036)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1039)..(1042)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1055)..(1055)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1067)..(1067)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1076)..(1076)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1082)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1094)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1125)..(1126)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1128)..(1128)
<223>  n is a, c, g, or t

<400>  257
ntagagaaat tactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg gggacaatga taagactcgc tatatgggga    120

agggtgtctc aaaggctgtt gagcacatca ataaaactat tgcgcctgcc ctggttagca    180

agaaactgaa cgtcacagaa caagagaaga ttgacaaact gatgatcgag atggatggaa    240

cagaaaataa atctaagttt ggtgcgaacg ccattctggg ggtgtccctt gccgtctgca    300

aagctggtgc cgttgagaag ggggtccccc tgtaccgcca catcgctgac ttggctggca    360

actctgaagt catcctgcca gtcccggcgt tcaatgtcat caatggcggt tctcatgctg    420

gcaacaagct ggccatgcag gagttcatga tcctcccagt cggtgcagca aacttcaggg    480

aagccatgcg cattggagca gaggtttacc acaacctgaa gaatgtcatc aaggagaaat    540

atgggaaaga tgccaccaat gtgggggatg aaggcgggtt tgctcccaac atcctggaga    600

ataaagaagg cctggagctg ctgaagactg ctattgggaa agctggctac actgataagg    660

tggtcatcgg catggacgta gcggcctccg agttcttcan gtctggggaa gtatgacctg    720

gacttcaagt ctcccgatga ccccagccag gtacatctcc ccctgaccag ctggctgaac    780

tgtanaagtc cttcatcaaa gnactaccca ntggngtcct atnnaaaaat ccctttgacc    840

aagatnactg gggnaacttt ggcaaaaaat ttcccancca ggggcangaa ntccaggtaa    900

ntgggggnat gatctcccna gngaacccaa ccccaaaaaa gganccccca aggccngnaa    960

ncaaaaaatn cttggaantn ccccctgntc caaattcanc caaanttggc nccccnngac   1020

ccaaannccc ttcaanggnn nnaaacttgg cccanaacca aaggttnggg cccccngggg   1080

tntccccccc cttncngggg naaaanaaaa aaaacctcct ccccnnanc               1129


<210>  258
<211>  1002
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (884)..(884)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (889)..(889)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (925)..(925)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (939)..(939)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (958)..(958)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (968)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1001)
<223>  n is a, c, g, or t

<400>  258
tagagngaat tactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg cattgcttga acaaaataat tgggacttag    120

tggcagctat caatggtgta ataccacagg aaaatggcat tctacaaagt gaatatggag    180

gtgagaccat accaggacct gcatttaatc cagcaagtca tccagcttca gctcctactt    240

cctcttcttc ttcagcgttt cgacctgtaa tgccatccag gcagattgta gaaaggcaac    300

ctcggatgct ggacttcagg gttgaataca gagacagaaa tgttgatgtg gtacttgaag    360

acacctgtac tgttggagag attaaacaga ttctagaaaa tgaacttcag atacctgtgt    420

ccaaaatgct gttaaaaggc tggaagacgg gagatgtgga agacagtacg gtcctaaaat    480

ctctacactt gccaaaaaac aacagtcttt atgtccttac accagatttg ccaccacctt    540

catcatctag tcatgctggt gccctgcagg agtcattaaa tcaaaacttc atgctgatca    600

tcacccaccg agaagtccag cgggagtaca acctgaactt ctcaggaagc agtactattc    660

aagaggtaaa gagaaatgtg tatgacctta caagtatccc cgttcgccac caattatggg    720

agggctggcc aacttctgct acagacgact caatgtgtct tgctgaatca gggctctctt    780

atccctgcca tcgacttaca gtgggaagaa gatcttcacc tgcacagacc cggggaacag    840

tcggaagaaa gaaagcttct tgctatctac ctccaccatg atgnaaagng tgttaaccaa    900

cgggttctgc tcacaaatgc tttgngctga atccattgnt tcttatctga gtcaaaantt    960

tataancnng ggcttgggga tctgacaaag gactcccaca na                      1002


<210>  259
<211>  1023
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (836)..(836)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (838)..(838)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (843)..(843)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (864)..(864)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (871)..(871)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (874)..(874)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (878)..(878)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (880)..(880)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (921)..(921)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (930)..(930)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (943)..(943)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (973)..(974)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (981)..(981)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1002)..(1002)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1008)..(1008)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1012)..(1013)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1021)..(1021)
<223>  n is a, c, g, or t

<400>  259
nttagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gcccagcaac acgctcctga cttcccttcc    120

caaggactcg acctgagaac cgccatgtac tcggagatcc agagggagcg ggcagacatt    180

gggggcctga tggcccggcc agaatacaga gagtggaatc cggagctcat caagcccaag    240

aagctgctga accccgtgaa ggcctctcgg agtcaccagg agctccaccg ggagctgctc    300

atgaaccaca gaaggggcct tggtgtggac agcaagccag agctgcagcg tgtcctagag    360

caccgccggc ggaaccagct catcaagaag aagaaggagg agctggaagc caagcggctg    420

cagtgcccct ttgagcagga gctgctgaga cggcagcaga ggctgaacca gctggaaaaa    480

ccaccagaga aggaagagga tcacgccccc gagtttatta aagtcaggga aaacctgcgg    540

agaattgcca cactgaccag cgaagagaga gagctgtagg gccagctgcc gggctcaggc    600

cactgcccac cctggcctgg acagcctcct tcagcccttc tgtacctggc agccctgggc    660

cccaggccct gggacgtctg tgatgttccc acctgcttct gtagaaatgt gtcaccccag    720

agggcctggc tctccctggg aggctggggc ccctaagctc ctaggttttc cttccaagca    780

cccagccctc ctgctccaag agggataacc tgcacccctc cctgcaaggg gttcanancc    840

cancacagga gctttctctg gcanaattga ngangaanan gtggccctct gacttgacaa    900

gccttctgtt ctgcccaggc nttccaccan gaatctccga ggntcccagg gcccgcttct    960

ccgtanaccc canntcntag ntctcaaaaa ctccccncct gnggtttnct gnnccnnnaa   1020

ntt                                                                 1023


<210>  260
<211>  1184
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (879)..(879)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (882)..(882)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (896)..(896)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (957)..(957)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (974)..(974)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1018)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1034)..(1034)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1062)..(1062)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1088)..(1088)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1126)..(1127)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1130)..(1130)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1132)..(1134)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1166)..(1166)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1169)..(1169)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1174)..(1174)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1177)..(1177)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1179)..(1179)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1181)..(1181)
<223>  n is a, c, g, or t

<400>  260
gagaaattac tatgagagga tcgcatcacc atcaccatca cggatcctat ttaggtgaca     60

ctatagaatc gtcgacccac gcgtccgcca tggctgagct gcagcagctc cgggtgcagg    120

aggcggtgga gtccatggtg aagagtctgg aaagagagaa catccggaag atgcagggtc    180

tcatgttccg gtgcagcgcc agctgttgtg aggacagcca ggcctccatg aagcaggtgc    240

accagtgcat cgagcgctgc catgtgcctc tggctcaagc ccaggctttg gtcaccagtg    300

agctggagaa gttccaggac cgcctggccc ggtgcaccat gcattgcaat gacaaagcca    360

aagattcaat agatgctggg agtaaggagc ttcaggtgaa gcagcagctg gacagttgtg    420

tgaccaagtg tgtggatgac cacatgcacc tcatcccaac tatgaccaag aagatgaagg    480

aggctctctt atcaattgga aaataaaagt atttgccagt ggccatcagg gctgagggca    540

agaatatatt ttttataagg aattgggaat tttagtcttt taagcaaagt ttacgaatga    600

agaaatgaag gatggccaca agcgtaaggc atatgtcact tgcctctgga cactggttat    660

tttatgtttc agtccctaaa aaatgaaatg gaaaaaagtg gtgctaaatc gagtcagaga    720

tattacagga gagttttaga gcttattatt tcctgtggcc agtgcttgtc ctggcagtaa    780

ggctctcccc tgtaacaagc cagagccctc caaggtacca gactcttctt actacacagg    840

tactaacagg ctggcaggtt aaagttggtg gagtctgang anagatattt ttctcntttg    900

ttgccaacat cctgtttacc aaaagtgtca ccccaccatc ttccataagc tgtgaancaa    960

aatcaatgag gtcnctaact taaaagggaa aaaaagtttt ctgggtcttt gttttctnga   1020

tttgggggta attnatacan ggcatacaag ttgattttaa angtggaact ggggaggtaa   1080

actaattnga aaaaancttt gaangntcct tgggaatccc catttnnggn cnnnaaaagg   1140

ggaaggacat tttttaaaaa tataanagng ggcnccntnc nccc                    1184


<210>  261
<211>  974
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (858)..(858)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (870)..(870)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (915)..(915)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (930)..(930)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (958)..(958)
<223>  n is a, c, g, or t

<400>  261
attagagnaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gcaaagaacg aacggcaggt gatgaagcca    120

ctatacgaca ggtaccggct ggtcaaacag atcctctccc gagctaacac catacccatc    180

attggttccc cctccagcaa gcggagaagc cctttgctgc agccaattat cgagggcgaa    240

actgcttcct tcttcaagga gataaaggaa gaagaggagg ggtcagaaga cgatagcaat    300

gtgaagccag acttcatggt cactctgaaa accgatttca gtgcacgatg ctttctggac    360

caattcgaag atgacgctga tggatttatt tccccaatgg atgataaaat accatcaaaa    420

tgcagccagg acacagggct ttcaaatctc catgctgcct caatacctga actcctggaa    480

cacctccagg aaatgagaga agaaaagaaa aggattcgaa agaaacttcg ggattttgaa    540

gacaactttt tcagacagaa tggaagaaat gtccagaagg aagaccgcac tcctatggct    600

gaagaataca gtgaatataa gcacataaag gcgaaactga ggctcctgga ggtgctcatc    660

agcaagagag acactgattc caagtccatg tgaggggcat ggccaagcac agggggctgg    720

cagctgcggt gagagtttac tgtccccaga gaaagtgcag ctctggaagg cagccttggg    780

gctggccctg caaagcatgc agcccttctg cctctagacc atttggcatc ggctcctggt    840

ttccattgcc tgccttanaa actggctggn aagaagacaa tgtggacctg acttaggcat    900

tttgtaattg gaaangtcaa gactggcagn tatgtgcaca tgcgcacgcg catgcacnca    960

cacacacacc cagt                                                      974


<210>  262
<211>  1179
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (895)..(895)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (918)..(918)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (946)..(946)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (990)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1010)..(1010)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1012)..(1012)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1027)..(1027)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1036)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1049)..(1050)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1054)..(1054)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1063)..(1063)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1074)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1085)..(1085)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1088)..(1088)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1108)..(1108)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1114)..(1115)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1127)..(1127)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1130)..(1130)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1137)..(1137)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1140)..(1141)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1149)..(1149)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1154)..(1154)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1173)..(1173)
<223>  n is a, c, g, or t

<400>  262
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggaatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg gtgtcatgga ggcctacgag caggtccaaa    120

agggacccct gaagctgaaa ggcgtcgcag agctgggagt gaccaagcgg aagaagaaaa    180

agaaggacaa agacaaagcg aaactcctgg aagcaatggg aacgagcaaa aagaacgagg    240

aggagaagcg gcgcggcctg gacaagcgga ccccggccca ggcggccttc gagaaaatgc    300

aggagaagcg gcaaatggaa aggatcctaa agaaggcatc caaaacccac aagcagagag    360

tggaggactt caacagacac ctggacacac tcacggagca ttacgacatt cccaaagtca    420

gctggacgaa gtagccgcct gcccccagta tggagcagca tcgagggttc gcaaaaggcc    480

acactggggt tgtgtgtgtt tcctttggta tattctggaa acatggctac acacaccctt    540

gcatcttctg ctacagactg cttttcgaag ctgtgtaccc tcattctgga acttgattaa    600

agtaagatcg tccttgtact cagtttaggc ttcttggcaa catacagaag atacaccctt    660

ttcgtttgga tggaaagttt ctaagtttat ccagaggtaa agcccattgt gtgtctgtgt    720

catgtaaaaa tgttttcacc cgagttgcat gtaacgctct gaggccagcc agctgtcttc    780

tcctggatga gacagactcc agagggtaag gagctagcgc catggtggcc tgcagtatgc    840

agagcccccg caggacccag cgtgggcgcc cttccagctt cctctagctt tgggncctat    900

gctgtcccct gcaggccnta gggaaacccc cttgcaacta tgcggncttt caaacttcct    960

cctcagccac ctggccnctg aaaacagccn tagcctgggt taacggaaan anccncctta   1020

aggcaanaat ggaannggaa ccccccttnn ctcnttttnt gancccgttt nccnaaaacc   1080

ccccnttnca ggtgcttntt aagggggntt gccnntaaca aaacctnctn aatggcntcn   1140

naacatttnt tttnaaatgg aaaccaaaaa aancctggc                          1179


<210>  263
<211>  1070
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (756)..(756)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (790)..(790)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (839)..(839)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (867)..(867)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (927)..(927)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (933)..(933)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (939)..(939)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (964)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (969)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (974)..(974)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (999)..(999)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1002)..(1002)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1004)..(1004)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1010)..(1010)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1014)..(1014)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1019)..(1019)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1031)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1039)..(1039)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1045)..(1045)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1051)..(1051)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1054)..(1054)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1056)..(1056)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1058)..(1058)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1060)..(1060)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1062)..(1062)
<223>  n is a, c, g, or t

<400>  263
ggaatagaga gaattactat gagaggatcg catcaccatc accatcacgg atcctattta     60

ggtgacacta tagaatcgtc gacccacgcg tccgctggga ctctgggagc agcagtgaag    120

tcttcagata ctgccctacc tccacctcca gtgcctccca aatctgaagc cgtcagagaa    180

gaatgccggc tcctgaacgc cccacctgtt ccaccccgaa gcgcaaagcc tttgtccacc    240

agtccctcca tccctcctcg cacagtcaag ccagcgcggc aacagactcg ctctcccagc    300

cccaccttgt cctactattc ttcagggcta cacaacatcg tcactaaaac tgacacaaat    360

ccttctgaaa gcactcctgt ttcctgctat ccatgtaacc gagtgaaaac tgattctgtg    420

gacctgaaat ccccgtttgg aagtccttct gctgaagctg tgtcctctcg gctctcatgg    480

cctaaccatt attcaggagc atcagaaagc cagaccagga gtgacttcct gctggatcca    540

agcaggagtt atagttaccc tagacaaaag acgccaggca caccaaagag aaactgccca    600

gcaccttttg attttgatgg ctgtgagctc ctggccagcc ccactagccc agtcactgca    660

gaattcagta gcagcgtctc tggttgtccc aagtcagcca gctactctct ggagagcaca    720

gatgtgaaat ctcttgcagc tggtgtgaca aagcanagta cgtcatgccc tgccttaccc    780

cccagggctn ccaaaactag tggaagagaa ggtcgcctcc gaaacatctc ctttgcctnt    840

gaaaattgat ggtgctgaag gaaaganccc aagtctgggg tcaccaaaat ctctcggagg    900

gaccagtatt tttggttaaa aaggggnatg gcnggaaant cttctctggc ctcctaacct    960

tttntnatnt ccgnctncaa tctccaagtg ggccccaana tncntntggn gaanggttnc   1020

cccatggaag nccacctgnt gaacntaatc nggnantntn tnaggaggga              1070


<210>  264
<211>  720
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (529)..(530)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (532)..(532)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (544)..(544)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (584)..(584)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (594)..(594)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (602)..(602)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (626)..(627)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (629)..(629)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (645)..(645)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (653)..(653)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (658)..(659)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (663)..(664)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (678)..(679)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (682)..(682)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (684)..(684)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (699)..(699)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (703)..(704)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (709)..(709)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (712)..(712)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (715)..(716)
<223>  n is a, c, g, or t

<400>  264
nantagagaa attaactatg gagaggatcg catcaccatc accatcacgg atcctattta     60

ggtgacacta tagaatcgtc gacccacgcg tccgcctgtg gctacctctg gccctgcgta    120

ttccccaggc ccagcctcgc caggccaggc ctattcagct gctcccccct cctcctgcgc    180

cccctcctcc tcctcttctt ctgaatggca ggaaccagtc ctggagccct tcgatccctt    240

tgagctgggg cagggcagtt ctccagagcc tgagctgctg cgttctcagg agcccagagc    300

agtggggaca cctgggcctg gaccccgcct ttcaccactt ggcccctcca aggcctttga    360

gcctgaaggt ttggtgctgc accaggtccc caccccactg tcaccagctg ctctgcaggg    420

acccgaggcg ggaggagcac tttttctaac ccaagggcgc ctggaagggc ctcctgccag    480

tccccgggat ggagccacag gctttggagt ccgagatgcc tcctcctgnn anccccctgc    540

tganctgtct gcactctccc tggaggaggt ctctcgcaat ctgngtttca tcgngctctc    600

anaggatgtg gtgagcttct ttgccnnana acgcatcgat ggtancatct ttntgcannt    660

canngaagac aatcctgnna anangacttt ccacctcanc aanntgaang tnaannaaaa    720


<210>  265
<211>  1214
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (8)..(9)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (811)..(811)
<223>  n is a, c, g, or t

<400>  265
cccacccnnc ctgagagata ctagagagga tcgcatcacc atcaccatca cggtcgaccc     60

acgcgtccgg gggagccggc tggcacagac ccagggctgg acgacctgga tgtggccctg    120

agcaacctgg aggtgaagct ggaggggtcg gcgcccacag atgtgctgga cagcctcacc    180

accatcccag agctcaagga ccatctccga atctttcggc cccggaagct gaccctgaag    240

ggctaccgcc aacactgggt ggtgttcaag gagaccacac tgtcctacta caagagccag    300

gacgaggccc ctggggaccc cattcagcag ctcaacctca agggctgtga ggtggttccc    360

gatgttaacg tctccggcca gaagttctgc attaaactcc tagtgccctc ccctgagggc    420

atgagtgaga tctacctgcg gtgccaggat gagcagcagt atgcccgctg gatggctggc    480

tgccgcctgg cctccaaagg ccgcaccatg gccgacagca gctacaccag cgaggtgcag    540

gccatcctgg ccttcctcag cctgcagcgc acgggcagtg ggggcccggg caaccacccc    600

cacggccctg atgcctctgc cgagggcctc aacccctacg gcctcgttgc cccccgtttc    660

cagcgaaagt tcaaggccaa gcagctcacc ccacggatcc tggaagccca ccagaatgtg    720

gcccagttgt cgctggcaga ggcccagctg cgcttcatcc aggcctggca gtccctgccc    780

gacttcggca tctcctatgt catggtcagg ntcaagggca gcaggaaaga cgagatcctg    840

ggcatcgcca acaaccgact gatccgcatc gacttggccg cgggcgacgt ggtcaaaacc    900

tggcgtttca gcaaaatggg ccaatggaat gtcaactggg aaatcccaca ggtggacatt    960

caaatttaat gaaaactccc atgcgtcctc ccctagcatc accggcccct cgcccaatgt   1020

aacacaacta tttcccgcgc taaatatctc cttccactcc caccacacac cccccgttga   1080

ttagctcaac aaactaactc ttcaaaagat aaccaatccc caccacatac tccgacttcc   1140

ttcatttaca acctccacct cacatcactt ctccacctca ccccctacaa tatccttcaa   1200

acgtctctac cact                                                     1214


<210>  266
<211>  1179
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (913)..(913)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (951)..(951)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (954)..(954)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (965)..(965)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1036)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1049)..(1049)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1078)..(1078)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1081)..(1081)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1085)..(1085)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1089)..(1089)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1123)..(1123)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1126)..(1126)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1138)..(1138)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1140)..(1140)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1145)..(1146)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1149)..(1149)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1155)..(1155)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1167)..(1167)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1172)..(1172)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1175)..(1176)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1178)..(1178)
<223>  n is a, c, g, or t

<400>  266
aattagagaa attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cgggaaaggg gactcagaag ctgaggcact    120

ctcagagata aaagatggtt cccttccacc cgaactgtct tgcatcccat cccacagagt    180

tctagggccc ccgacttcaa ttccacctga gcccctaggc cctgtatcca tggactctga    240

gtgtgaggag tcacttgctg ccagcccaat ggcagctaag cccgacaacc catcaggaaa    300

ggtctgtgtc agggaagtag caccagatgg cccactacaa gaaagctcca caagactgtc    360

cctgacctca gaccccgagg agggggaccc actggcctta gggcctgaaa gcccaggaga    420

gcctcagcct ccacagctca agaaagatga tgtcactagc tccaccggtc cccacaagga    480

gctgtcaagc acagaggcag gttccacagt tgcaggagca gccctcagac ccagccatca    540

ttcccagcgt tccagtctct ctggggatga agaggatgaa ctgtttaaag gggcaactct    600

gaaagctctg aggcccaaag cacagcctga ggaggaggat gaagacgagg tgagcatgaa    660

gggacgcccg cccccaacgc ccctttttgg agatgatgat gatgacgatg acattgactg    720

gctgggatga agacccagga aactggtgca aaggtttctc tgcaaccctt ccctaagcat    780

gattttgcac agccaaccct gggtctaggc gagccacagg gtgaggtcaa ggtgagcatt    840

ctgggaacaa tatttgggct cagagggtgg gttggccacc ttctgagccc cacccccgcc    900

agacctggtg aanaggatca taaccctgtc ttcaaaacac tgggatttca ncancaagtt    960

ggaanaagga ctggtangtt ccctccnagc cagtcacctg taaaantcct gtcctctgcc   1020

aaatttttaa tctctncata actcccaant gactggganc cctctctact tgaatccntg   1080

ntcantggnc ccggcaanaa actggntgag tttcctggta aantanggaa ttaccctntn   1140

atccnnggnt caaanctggc taaatcngga anganntnt                          1179


<210>  267
<211>  1166
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (932)..(932)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (941)..(941)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (954)..(954)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (978)..(978)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (986)..(986)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (995)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1010)..(1010)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1075)..(1075)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1112)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1123)..(1123)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1137)..(1137)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1144)..(1145)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1147)..(1147)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1150)..(1150)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1157)..(1157)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1160)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1163)..(1163)
<223>  n is a, c, g, or t

<400>  267
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg gcctggctcc tggccgccgt ctgggtcctg    120

gcacccgcct ctccctggct cgaatgcccc ctccactccc gacccgggtg gatttctccc    180

tggctggggc actcaatgct ggcttcaagg agacccgggc cagtgagcgg gcagagatga    240

tggagctcaa tgaccgcttt gccagctaca tcgagaaggt tcgcttcctg gaacagcaaa    300

acaaggcgct ggctgctgag ctgaaccagc tgcgggccaa ggagcccacc aagctggcag    360

acgtctacca ggctgagctg cgagagctgc ggctgcggct cgatcaactc accgccaaca    420

gcgcccggct ggaggttgag agggacaatc tggcacagga cctggccact gtgaggcaga    480

agctccagga tgaaaccaac ctgaggctgg aagccgagaa caacctggct gcctatagac    540

aggaagcaga tgaagccacc ctggcccgtc tggatctgga gaggaagatt gagtcgctgg    600

aggaggagat ccggttcttg aggaagatcc acgaggagga ggttcgggaa ctccaggagc    660

agctggcccg acagcaggtc catgtggagc ttgacgtggc caagccagac ctcaccgcag    720

ccctgaaaga gatccgcacg cagtatgagg caatggcgtc cagcaacatg catgaagccg    780

aagagtggta ccgctccaag tttgcagacc tgacagacgc tgctgcccgc aacgcggagc    840

tgctccgcca ggccaagcac gaagccaacg actaccggcg ccagttgcag tccttgacct    900

gcgacctgga gtctctgcgc ggcacgaacg antccttgga naggcaaatg cccnancagg    960

aagaacggca cgtgcggnag gcgncnantt atcangaagc nctgncccgn ctgaagaaaa   1020

agggcaaaac ctcangaaca aatggccccc ccttgcagga atacaagaac tgctnatgtc   1080

agctggcctg aaatcnaaat ccccctaagn anctgctaag ggnaagaaaa cggatcncat   1140

tccnngnaan cttttcnacn tgnaat                                        1166


<210>  268
<211>  883
<212>  DNA
<213>  Homo sapiens

<400>  268
catcaccatc accatcacgg atcctattta ggtgacacta tagaatcgtc gacccacgcg     60

tccgtgcgtg cggcgggaat catggctgct cgcagagctc tgcacttcgt attcaaagtg    120

ggaaaccgct tccagacggc gcgtttctat cgggacgtcc tggggatgaa ggttctgcgg    180

catgaggaat ttgaagaagg ctgcaaagct gcctgtaatg ggccttatga tgggaaatgg    240

agtaaaacaa tggtgggatt tgggcctgag gatgatcatt ttgtcgcaga actgacttac    300

aattatggcg tcggagacta caagcttggc aatgacttta tgggaatcac gctcgcttct    360

agccaggctg tcagcaacgc caggaagctg gagtggccac tgacggaagt tgcagaaggt    420

gtttttgaaa ccgaggcccc gggaggatat aagttctatt tgcagaatcg cagtctgcct    480

cagtcagatc ctgtattaaa agtaactcta gcagtgtctg atcttcaaaa gtccttgaac    540

tactggtgta atctactggg aatgaaaatt tatgaaaaag atgaagaaaa gcaaagggct    600

ttgctgggct atgctgataa ccagtgtaag ctggagctac agggcgtcaa gggtggggtg    660

gaccatgcag cagcttttgg aagaattgcc ttctcttgcc cccagaaaga gttgccagac    720

ttagaagact tgatgaaaag ggagaaccag aagattctga ctcccctggt gagcctggac    780

accccaggga aaagcaacag tacaggtggt cattctggcc gaccctgacg gacatgaaat    840

ttgctttgtc ggggatgaag catttcgaga actttctaag atg                      883


<210>  269
<211>  1171
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (888)..(888)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (922)..(922)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (947)..(947)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (963)..(963)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1019)..(1019)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1023)..(1023)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1042)..(1042)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1057)..(1057)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1074)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1088)..(1088)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1090)..(1090)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1093)..(1093)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1095)..(1095)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1103)..(1103)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1105)..(1105)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1109)..(1109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1120)..(1120)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1124)..(1124)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1132)..(1132)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1141)..(1142)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1145)..(1145)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1148)..(1148)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1152)..(1152)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1168)..(1168)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1171)..(1171)
<223>  n is a, c, g, or t

<400>  269
atagagagaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gggcaaaaag caattgcaga agttgatgtg    120

ggtacagata aggcccagaa ttctgacccg atacttgata cttcatcact agttcctgga    180

tgttcctctg tagataacat caagtcatct caaacctcac aaaaccaggg acttggacgt    240

cctactcttg aaggtgatga agagacttca gaggttgagt acacagtgaa taagggccca    300

gcttccagca atagagacag ggtaccacct tcatctgaag ctagtgagca tcacccgcgg    360

catcgtgttt caagtcaagc ggaagatact tccagcagct ttgacaacct gtttattgac    420

aggttacaga ggatcaccat tgcggaccaa ggtgaacaac agtcagaaga aaacgcaagt    480

actaagaact tgacaggcct ttccagtggg actgagaaga aacctcatta catggaagtg    540

ctagaaatgc gagccaaaaa cccagtgccc cagctgcgta aatttaaaac caatgtgtta    600

ccttttcgac aaaatgattc atctagtcat tgccagaaga gtgggtctcc tatttcctca    660

gaagagcggc ggcgcaggga taagcagcat cttgatgaca tcacagcagc tcggcttcta    720

ccacttcacc atatgcccac gcagctgctc tccatagaag aatccttggc acttcagaaa    780

cagcagaaac agaattatga ggagatgcaa gcaaagctcg cagcgcaaaa attagctgaa    840

agactgaata ttaaaatgcg gagttataat ccagaagggg agtcttcngg gagataccga    900

gaagtaaggg atgaagatga cnattggtcc tctgatgaat tctgaanata atctcctaaa    960

tcnctgacgt tgaaatgtca tcatcttaca tcaaactttc taactagtat cagatcagng   1020

tcnaaattgt tgagggaagt antttataaa gttaccnang gtagtttaaa aaanccccat   1080

ttgtcttncn aangngactt ncngngctng aaaggttaan tttngaaatt gngtttaccc   1140

nnggnatnaa antttgcaaa aattgggnat n                                  1171


<210>  270
<211>  461
<212>  DNA
<213>  Homo sapiens

<400>  270
atgcgtggtc gtgaactgcc gctggttctg ctggcactgg ttctgtgtct ggcaccgcgt     60

ggtcgtgcag ttccgctgcc tgctggcggt ggtacagttc tgaccaaaat gtatccgcgt    120

ggtaatcatt gggcagttgg tcatctgatg ggtaaaaaaa gcaccggtga aagcagcagc    180

gttagcgaac gtggtagcct gaaacagcag ctgcgtgaat atattcgttg ggaagaagca    240

gcacgtaatc tgctgggtct gattgaagca aaagaaaatc gcaatcatca gcctccgcag    300

ccgaaagcac tgggtaatca gcagccgagc tgggatagcg aagatagcag caactttaaa    360

gatgtgggca gcaaaggtaa agttggtcgt ctgagcgcac cgggtagcca gcgtgaaggt    420

cgtaatccgc agctgaatca gcagtaagcg gccgcgagct c                        461


<210>  271
<211>  802
<212>  DNA
<213>  Homo sapiens

<400>  271
ctatgagagg tcgcatcacc atcaccatca cggatcctat ttaggtgaca ctatagaatc     60

gtcgacccac gcgtccgggt tgagctgctg ccgccgccgc ctctgtcgtc gtcgcgagtg    120

tggagtcggg actggagctg ctgccgcggc gacgccgggg atctttgtcg ctagctcccg    180

gcccttctgc cccgccgcct tccctcagtc agcgttgccc actcctctcc ggccgggcgc    240

ccctgcctcc atttctcgct ctctgtccac cacacacacg gcccccccga tcatggatcc    300

gggcagtggc ggcggcggcg gcggcggcgg cggcggcggc gggagcagca gcggcagcag    360

cagcagcgac tcggcgcctg actgctggga ccaggcggac atggaagccc ccgggccggg    420

cccttgcggc ggcggcggct ccctggcggc ggcggccgag gcccagcggg agaacctcag    480

cgcggccttc agccggcaac tcaacgtcaa cgccaagccc ttcgtgccca acgtccacgc    540

cgccgagttc gtgccgtcct tcctgcggtg cccggcagcg ccgccacccc cagctggcgg    600

cgccgccaat aaccacggag ccggcagcgg cgcgggaggc cgtgcggcac ctgtggaatc    660

ctctcaagag gaacagtcat tgtgtgaagg ttcaaattca gctgttagca tggaactttc    720

agaacctatt gtagaaaatg gagagacaga aatgtctcca gaagaatcat gggagcacaa    780

agaagaaata agtgaagcag ag                                             802


<210>  272
<211>  897
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (794)..(794)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (798)..(799)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (817)..(817)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (826)..(826)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (849)..(849)
<223>  n is a, c, g, or t

<400>  272
atagagagat actatgagag gtcgcatcac catcaccatc acggatccta tttaggtgac     60

actatagaat cgtcgactct ggaccttggc tgtcactcag ttaagaattt attaataatg    120

tgtaaggaga aggagaagct acagaaaaag gcccacgagc tgaagcgcag gcttctcctc    180

tctcagagga agcgggagct ggcagatgtc ctggatgccc agatcgagat gctcagcccc    240

ttcgaggcag tggccacacg cttcaaggag caatacagga cattcgccac ggccctggac    300

gctaccaggc acgagctgcc cgtgaggtcc atccacctgg agggagatgg gcagcagctc    360

ttagacgccc tgcagcatga actggtgacc actcagcgcc tcctgggaga acttgatgtt    420

ggtgattcgg aagaaaatgt gcaggtgctg gacttactga gcgaactcaa ggacgtgaca    480

gcgaaaaagg accttgagct ccgaaggagc tttgcccagg tgctggaact ctccgcagag    540

gcaagcaaag aggcagcctt ggcaaaccag gaagtctggg aagagaccca gggcatggcg    600

ccccccagcc ggtggtattt caatcaagac agtgcctgca gagaatctgg gggagcaccc    660

aagaacacgc ccctgtctga ggacgacaac ccgggtgcct cgtcagcccc cgctcaggcc    720

acgttcatca gcccaagcga agaatttttc ttcagcagcc aggcagaagt cccgcctctc    780

tctctcgttc aggnaggnna ctgtcatgac tcatggntac attcangata cttgagcact    840

ttaatactna cgtacactgt agctattttt atgtgataat ctgttgataa aaagtaa       897


<210>  273
<211>  1334
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (876)..(876)
<223>  n is a, c, g, or t

<400>  273
ncccgtgcct nctaagagat actagagagg atcgcatcac catcaccatc acggtcgacc     60

cacgcgtccg gccaccctct caagccaggt gatcaacccc actgccatca ctgtgtcggc    120

cgcacagacc acgctgacag cggcaggcgg gctcacaacc ccaaccatca ccatgcagcc    180

cgtgtcccag cccacccagg taactctgat cacggcacct agtggggtgg aggcccagcc    240

tgtgcatgac ctccctgtgt ccattctggc ctccccgact acagaacagc ccaccgccac    300

agttaccatc gccgactcag gccagggtga tgtgcagcct ggcactgtca ccttggtgtg    360

ctccaaccca ccctgtgaga cccacgagac tggcaccacc aacacggcca ccactactgt    420

tgtggctaac cttgggggac acccccagcc cacccaagtg cagttcgtct gtgacagaca    480

ggaggcagct gcttctcttg tgacctcgac tgtgggccag cagaatggta gcgtggtccg    540

agtctgttcg aacccgccct gcgagaccca cgagacgggc accaccaaca ccgccaccac    600

cgccacctcc aacatggccg ggcagcatgg ctgctcaaac ccaccctgcg agacccacga    660

gacgggcacc accaacactg ccactacagc catgtcgagc gtcggcgcca accaccagcg    720

agatgcccgt cgggcctgtg cagctggcac ccctgccgtg atccggatca gtgtggccac    780

tggggcgctg gaggcagccc agggttctaa agtcccatgc caaacccgcc agaacagcgc    840

gaccacacca ccatgactgg gatgggcaac gggggncccc gggttcgccg gcccaattcc    900

tggggccaac atggaaccga accccggggg ccccacccct gttttgggca atttgccccc    960

ctgacaaaca aaaccaggtg gaacacccca aactttagga ctttcctggg ggcgccccaa   1020

cactggggca acacccctcc aaaacctttt caccggaggg tttccgacac caccctaact   1080

cttcacccac aacctaaaca tcattacacc aacctaactc tatctaactc aacccccaaa   1140

tttctcacct actccctcca atcaaaaatc tatccacatc acaacatata acacaccacc   1200

ctccacacca cacctccaac ccacacattc acttaaccta cccaatacat ccacaaaact   1260

catcccccat cacaacctac tctttaacca cacaccataa aatcattatt accatcaacc   1320

tcttttccac ttac                                                     1334


<210>  274
<211>  872
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (722)..(722)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (737)..(737)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (744)..(744)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (774)..(774)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (781)..(781)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (808)..(809)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (840)..(840)
<223>  n is a, c, g, or t

<400>  274
atagagaatt actatgagag gtcgcatccc atcaccatca cggatcctat ttaggtgaca     60

ctatagaatc gtcgactctg gaccttggct gtcactcagt ttttcgcaag gtgcgcgaca    120

gcactggagc acgtgtcatc ttccctgcgg ctgaggacaa ggaccaggac ctgatcacca    180

tcattggaaa ggaggacgcc gtccgagagg cacagaagga gctggaggcc ttgatccaaa    240

acctggataa tgtggtggaa gactccatgc tggtggaccc caagcaccac cgccacttcg    300

tcatccgcag aggccaggtc ttgcgggaga ttgctgaaga gtatggcggg gtgatggtca    360

gcttcccacg ctctggcaca cagagcgaca aagtcaccct caagggcgcc aaggactgtg    420

tggaggcagc caagaaacgc attcaggaga tcattgagga cctggaagct caggtgacat    480

tagaatgtgc tataccccag aaattccatc gatctgtcat gggccccaaa ggttccagaa    540

tccagcagat tactcgggat ttcagtgttc aaattaaatt cccagacaga gaggagaacg    600

cagttcacag tacagagcca gttgtccagg agaatgggga cgaagctggg gaggggagag    660

aggctaaaga ttgtgacccc ggctctccaa ggaggtgtga catcatcatc atctctggcg    720

gnaaagaaaa gtgtgangct gccnaggaag ctctggaggc attggttcct gtcnacattg    780

nagtagaggt gccctttgac cttcacgnnt acgtatgggc agaaggaagt ggatcgcagn    840

atgatgatga gtttgagtga catactgtcc gg                                  872


<210>  275
<211>  1177
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (808)..(808)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (827)..(827)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (852)..(852)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (869)..(869)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (884)..(884)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (891)..(891)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (897)..(897)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (901)..(901)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (921)..(921)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (923)..(923)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (929)..(930)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (955)..(955)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (964)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (975)..(975)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (994)..(994)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1000)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1003)..(1003)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1016)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1026)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1028)..(1028)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1032)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1034)..(1034)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1049)..(1049)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1072)..(1072)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1115)..(1115)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1119)..(1119)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1131)..(1131)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1164)..(1164)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1167)..(1168)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1170)..(1171)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1173)..(1176)
<223>  n is a, c, g, or t

<400>  275
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg caaaaaagat ctgacagagt acttgtctcg    120

atttggggaa gttgtagact gcacaattaa aacagatcca gtcactggga gatcaagagg    180

atttggattt gtgcttttca aagatgctgc tagtgttgat aaggttttgg aactgaaaga    240

acacaaactg gatggcaaat tgatagatcc caaaagggcc aaagctttaa aagggaaaga    300

acctcccaaa aaggtttttg tgggtggatt gagcccggat acttctgaag aacaaattaa    360

agaatatttt ggagcctttg gagagattga aaatattgaa cttcccatgg atacaaaaac    420

aaatgaaaga agaggatttt gttttatcac atatactgat gaagagccag taaaaaaatt    480

gttagaaagc agataccatc aaattggttc tgggaagtgt gaaatcaaag ttgcacaacc    540

caaagaggta tataggcagc aacagcaaca acaaaaaggt ggaagaggtg ctgcagctgg    600

tggacgaggt ggtacgaggg gtcgtggccg aggtcagggc caaaactgga accaaggatt    660

taataactat tatgatcaag gatatggaaa ttacaatagt gcctatggtg gtgatcaaaa    720

ctatagtggc tatggcggat atgattatac tgggtataac tatgggaact atggatatgg    780

acagggatat gcagactaca gtggccanca gagcacttat ggcaagncat ctcgaggggg    840

tggcaatcac cnaaaacaat taccagccnt actaaaggaa aacnttggaa naaaacnggg    900

nggagatgtt aaagtaaccc ntncttgcnn gacgaccttg aaaaattggc cctcnggtga    960

atcnaagagg aatanttttg taaaaaanct ttcntagggn ncnaaacccc ctttgnggcc   1020

cactgntnaa ancngcccan taagtttcnt tggttttacc ttggcccttg cnaacccggg   1080

gtaagaccca aggggaattg gttaaacccn ttttnttgna ccattcccgg naaaccccca   1140

aaaaagcctt cccttttggg aaanaannan nannnna                            1177


<210>  276
<211>  1337
<212>  DNA
<213>  Human


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (15)..(15)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (922)..(922)
<223>  n is a, c, g, or t

<400>  276
nncccactcc cnccncctag gatactagag aggatgcatc accatcacca tcacggtcga     60

cccacgcgtc cgctttcaga gctgttaagg tactacacat ctgcctctgg tgatgagatg    120

gtttctctca aggactactg caccagaatg aaggagaacc agaaacatat ctattatatc    180

acaggtgaga ccaaggacca ggtagctaac tcagcctttg tggaacgtct tcggaaacat    240

ggcttagaag tgatctatat gattgagccc attgatgagt actgtgtcca acagctgaag    300

gaatttgagg ggaagacctt agtgtcagtc accaaagaag gcctggaact tccagaggat    360

gaagaagaga aaaagaagca ggaagagaaa aaaacaaagt ttgagaacct ctgcaaaatc    420

atgaaagaca tattggagaa aaaagttgaa aaggtggttg tgtcaaaccg attggtgaca    480

tctccatgct gtattgtcac aagcacatat ggctggacag caaacatgga gagaatcatg    540

aaagctcaag ccctaagaga caactcaaca atgggttaca tggcagcaaa gaaacacctg    600

gagataaacc ctgaccattc cattattgag accttaaggc aaaaggcaga ggctgataag    660

aacgacaagt ctgtgaagga tctggtcatc ttgctttatg aaactgcgct cctgtcttct    720

ggcttcagtc tggaagatcc ccagacacat gctaacagga tctacaggat gatcaaactt    780

ggtctgggta ttgatgaaga tgaccctact gctgatgata ccagtgctgc tgtaactgaa    840

gaaatgccac ccctttgaag gagatgacga cacatcacgc attggaagaa gtagactaat    900

ctctggctga gggatgacta ancctggtca gtactctaca atcctctgat attatttttc    960

caaggatgtt tttcctttat tttggtaata ataaaaaggc tgtatgcatg acactacttt   1020

aagggaaaga aaaaattctg tcactaaggg aggcggggat acttagcact aagcaaacta   1080

gaaggctttt taggtcccgg gggggttatt tcccaaaagg ggggaacggc cccgtaaacc   1140

atgaaaatat ggttactttt ggcgggccaa agggttatcg tccacccggt ccaaaaaaaa   1200

aatttttttt gagagccccg ccacctcctt gtaaaaaaaa atctcccctt cgggaacttc   1260

cctattctct ctcgcgggaa aaatactgcg aacccccaaa aagaacacaa ccctgtgggg   1320

gcccccccgc ttccccc                                                  1337


<210>  277
<211>  1308
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (935)..(935)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (960)..(960)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (963)..(963)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (976)..(976)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (986)..(986)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1018)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1028)..(1028)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1042)..(1042)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1053)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1056)..(1056)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1062)..(1062)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1065)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1092)..(1092)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1094)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1112)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1122)..(1122)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1125)..(1125)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1128)..(1128)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1164)..(1164)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1167)..(1167)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1190)..(1191)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1213)..(1213)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1254)..(1254)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1265)..(1266)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1273)..(1274)
<223>  n is a, c, g, or t

<400>  277
atagagagat tactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg cccacgcgtc cgaaaagagc gattacatta    120

agctctatgt gcgccgtgta ttcatcacag acgacttcca tgatatgatg cctaaatacc    180

tcaattttgt caagggtgtg gtggactcag atgatctccc cttgaatgtt tcccgcgaga    240

ctcttcagca acataaactg cttaaggtga ttaggaagaa gcttgttcgt aaaacgctgg    300

acatgatcaa gaagattgct gatgataaat acaatgatac tttttggaaa gaatttggta    360

ccaacatcaa gcttggtgtg attgaagacc actcgaatcg aacacgtctt gctaaacttc    420

ttaggttcca gtcttctcat catccaactg acattactag cctagaccag tatgtggaaa    480

gaatgaagga aaaacaagac aaaatctact tcatggctgg gtccagcaga aaagaggctg    540

aatcttctcc atttgttgag cgacttctga aaaagggcta tgaagttatt tacctcacag    600

aacctgtgga tgaatactgt attcaggccc ttcccgaatt tgatgggaag aggttccaga    660

atgttgccaa ggaaggagtg aagttcgatg aaagtgagaa aactaaggag agtcgtgaag    720

cagttgagaa agaatttgag cctctgctga attggatgaa agataaagcc cttaaggaca    780

agattgaaaa ggctgtggtg tctcagcgcc tgacagaatc tccgtgtgct ttggtggcca    840

gccagtacgg atggtctggc aacatggaga gaatcatgaa agcacaagcg taccaaacgg    900

gcaaggacat ctctacaaat tactatgcga gtcanaaaaa acatttgaaa ttaatcccan    960

acncccgctg atcaanacat gcttcnacga attagggaag atgaanatga aaaaccantt   1020

tggatctngc tgggntttgt tngaaacacc acnctncggt cnggnatctt ttcccgacct   1080

aagctatgga ananaaaaaa aaangctccc cncatttgaa cntgnccnga gccaaggggg   1140

aaaaaacccc aaaaaacctg aaanccncca aaacccccaa aacccacccn nccaaaaaaa   1200

atgggggggg acnaataaaa aaaccccagg atcccccgaa aaaaaatgga attncccccc   1260

cttgnncggg ggnngaggaa attccttttt tgggaaaagt tgggcccc                1308


<210>  278
<211>  1493
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (11)..(12)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (761)..(761)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(987)
<223>  n is a, c, g, or t

<400>  278
nccccacccc nnctaagaat actagagagg atgcatcacc atcaccatca cggtcgaccc     60

acgcgtccga cggccgccgc catcgcctac ggcctggaca gaacgggcaa gggggagcgc    120

aacgtgctca tctttgacct gggcgggggc accttcgacg tgtccatcct gacgatcgac    180

gacggcatct tcgaggtgaa ggccacggcc ggggacaccc acctgggtgg ggaggacttt    240

gacaacaggc tggtgaacca cttcgtggag gagttcaaga gaaaacacaa gaaggacatc    300

agccagaaca agcgagccgt gaggcggctg cgcaccgcct gcgagagggc caagaggacc    360

ctgtcgtcca gcacccaggc cagcctggag atcgactccc tgtttgaggg catcgacttc    420

tacacgtcca tcaccagggc gaggttcgag gagctgtgct ccgacctgtt ccgaagcacc    480

ctggagcccg tggagaaggc tctgcgcgac gccaagctgg acaaggccca gattcacgac    540

ctggtcctgg tcgggggctc cacccgcatc cccaaggtgc agaagctgct gcaagacttc    600

ttcaacgggc gcgacctgaa caagagcatc aaccccgacg aggctgtggc ctacggggcg    660

gcggtgcagg cggccatcct gatgggggac aagtccgaga acgtgcagga cctgctgctg    720

ctggacgtgg ctcccctgtc gctggggctg gagacggccg naggcgtgat gactgccctg    780

atcaagcgca actccaccat ccccaccaag cagaccgcaa tcttccccac ctactccgaa    840

acccaccccg ggtgctgatc ccagtgtacg aaggcgaaag gcccttacta aaaacacaac    900

cttgttgggc cgctccagtt gaccgaatcc ccccgccccc cggggccggc ccccaaaaca    960

ggggaccttc aacaccaagg ccacggnatc ctaaactccg gccccggaaa aaaaccctca   1020

cagacgccac aaaccccctc cctacttcaa ggccccctct ccacgaagaa atcttgtcct   1080

tggctctacg gcaccaaacc caatccacat ctcattctct cttcaaactt ccacccacaa   1140

ccccatggct cctacctccc ataccccacc cctaatgata ggcgctcctc taaacctctc   1200

gagccactaa caaaacctcc catatcttct acacacttct gtacgccaac cctctcacat   1260

ttcgcaacct cacctcccac tccccaccgt cccgctcccc acctcccctc ctcacgcccc   1320

taccccgaca atacctgcca acctgtcgtg tccccaccac cccctcccct cccaccttcc   1380

ccctactcta agccctcagc acctcctact acctcccacc cttccactcc tctccctcca   1440

catacccatc ctatattcac tcctccctct gaccccccca cccccccata ctc          1493


<210>  279
<211>  942
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (605)..(605)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (692)..(692)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (722)..(722)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (736)..(736)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (804)..(804)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (841)..(841)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (847)..(847)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (852)..(852)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (864)..(864)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (869)..(870)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (884)..(884)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (888)..(888)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (890)..(891)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (902)..(902)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (909)..(910)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (915)..(917)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (919)..(919)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (921)..(923)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (929)..(930)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (932)..(932)
<223>  n is a, c, g, or t

<400>  279
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc tagagcagag tcagccagca tgaccgagcg    120

ccgcgtcccc ttctcgctcc tgcggggccc cagctgggac cccttccgcg actggtaccc    180

gcatagccgc ctcttcgacc aggccttcgg gctgccccgg ctgccggagg agtggtcgca    240

gtggttaggc ggcagcagct ggccaggcta cgtgcgcccc ctgccctccg ccgccatcga    300

gagccccgca gtggccgcgc ccgcctacag ccgcgcgctc agccggcaac tcagcagcgg    360

ggtctcggag atccggcaca ctgcggaccg ctggcgcgtg tccctggatg tcaaccactt    420

cgccccggac gagctgacgg tcaagaccaa ggatggcgtg gtggagatca ccggcaagca    480

cgaggagcgg caggacgagc atggctacat ctcccggtgc ttcacgcgga aatacacgct    540

gccccccggt gtggacccca cccaagtttc ctcctccctg tcccctgagg gcacactgac    600

cgtgnaggcc cccatgccca agctagccac gcagtccaac gagatcacca tcccagtcac    660

cttcgagtcg cgggcccagc ttgggggccc anaagctgca aaatccgatg agactgccgc    720

cnaagtaaag ccttangccc ggatgcccac ccctgctgcc gccactggct gtgcctcccc    780

ccgccaactg tgtgttcttt tganacattt atcttctgtt tttctcaaat aaagttcaaa    840

ncaaccnccc anaaaataaa aaanaaaann ataataataa aaanaatnan nttaatagaa    900

tntaaaaann atttnnnana nnntataann anaaaggggg gg                       942


<210>  280
<211>  843
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (679)..(679)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (733)..(733)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (739)..(739)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (766)..(766)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (791)..(791)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (812)..(812)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (823)..(823)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (825)..(825)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (834)..(834)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (843)..(843)
<223>  n is a, c, g, or t

<400>  280
tagagagatt acttgagagg atgcatcacc atcaccatca cggatcctat ttaggtgaca     60

ctatagaatc gtcgactctg gaccttggct gtcactcagt taaaaacaca gtcaccaccg    120

ggatcgtgag caccacccag cgaggcggca aagagctggg gctccgcaac tcagacatgg    180

actacatcca gaccgacgcc atcatcaact atggaaactc gggaggcccg ttagtaaacc    240

tggacggtga agtgattgga attaacactt tgaaagtgac agctggaatc tcctttgcaa    300

tcccatctga taagattaaa aagttcctca cggagtccca tgaccgacag gccaaaggaa    360

aagccatcac caagaagaag tatattggta tccgaatgat gtcactcacg tccagcaaag    420

ccaaagagct gaaggaccgg caccgggact tcccagacgt gatctcagga gcgtatataa    480

ttgaagtaat tcctgatacc ccagcagaag ctggtggtct caaggaaaac gacgtcataa    540

tcagcatcaa tggacagtcc gtggtctccg ccaatgatgt cagcgacgtc actaaaaggg    600

aaagcaccct gaacatggtg gtccgcaggg gtaatgaaga tatcatgatc acagtgattc    660

ccgagaaatt gacccatang cagaggcatg agctggactt catgtttccc tcaagactct    720

cccgtggatg acngatgang actctgggct gctggaatag acactncaga ctttgactgc    780

ccatttgttt ngtcagtgga gactccctgg cnacagaatc ctncntgata gttngcaggc    840

aan                                                                  843


<210>  281
<211>  956
<212>  DNA
<213>  Homo sapiens

<400>  281
tgagaggtcg catcaccatc accatcacgg atcctattta ggtgacacta tagaatcgtc     60

gacccacgcg tccgctcagg agcttgatcc agacctctac aagcaaatgg agaagttcag    120

gaaggtacaa acacaagtgc gccttgcaaa aaaaaacttt gacaaattga agatggatgt    180

ttgtcaaaaa gtggatcttc ttggagcgag cagatgcaat ctcttgtctc acatgctagc    240

aacataccag accactctgc ttcatttttg ggagaaaact tctcacacta tggcagccat    300

ccatgagagt ttcaaaggtt atcaaccata tgaatttact actttaaaga gcttacaaga    360

ccctatgaaa aaattagttg agaaagaaga gaagaagaaa atcaaccagc aggaaagtac    420

agatgcagcc gtgcaggagc cgagccaatt aatttcatta gaggaagaaa accagcgcaa    480

ggaatcctct agttttaaga ctgaagatgg aaaaagtatt ttatctgcct tagacaaagg    540

ctctacacat actgcatgct caggacccat agatgaacta ttagacatga aatctgagga    600

aggtgcttgc ctgggaccag tggcagggac cccggaacct gaaggtgctg acaaagatga    660

cctgctgctg ttgagtgaga tcttcaatgc ttcctccttg gaagagggcg agttcagcaa    720

agagtgggcc gctgtgtttg gagacggcca agtgaaggag ccagtgccca ctatggccct    780

gggagagcca gaccccaaag gcccagacag gctcaggttt ccttccttcg cagcttttag    840

accaaaatat gaaagactta caggcctcgc tacaagaacc tgctaaggct gcctcagacc    900

tgactgcctg gttcagcctc ttcgctgacc tcgaccccac tctcaatcct gatgct        956


<210>  282
<211>  973
<212>  DNA
<213>  Homo sapiens

<400>  282
tgagaggatc gcatcaccat caccatcacg gatcctattt aggtgacact atagaatcgt     60

cgacccacgc gtccgcccac gcgtccgctc ctgaggctga catgaatatt tttgaagaca    120

ttggggatta cgtaccctcc acaaccaaga cacctcggga caaggagcgg gagagatatc    180

gggaacggga gcgtgatcgg gaaagagaca gagaccgtga ccgagagcga gagcgagaac    240

gagatcggga acgagagcga gagcgggacc gagagagaga agaggaaaag aagagacaca    300

gctactttga gaagccaaaa gtagatgatg agcccatgga cgttgacaaa ggacctgggt    360

ctaccaagga gttgatcaag tccatcaatg aaaagtttgc tgggtctgct ggctgggaag    420

gcacagaatc gttgaagaag ccagaagaca aaaagcagct gggagatttc tttggcatgt    480

ccaacagtta tgcagagtgc tacccagcca cgatggatga catggctgtg gatagtgatg    540

aggaggtgga ttatagcaaa atggaccagg gtaacaagaa ggggccctta ggccgttggg    600

actttgatac ccaggaagaa tacagcgagt atatgaacaa caaagaagct ttgcccaagg    660

ctgcattcca gtatggtatc aaaatgtctg aagggcggaa aaccaggcgc ttcaaggaaa    720

ccaatgacaa agcagagctt gatcgccagt ggaagaagat tagtgcaatc attgagaaga    780

ggaagaagat ggaagctgat ggggttgaag tcaaaagacc aaaatactaa tcactagtta    840

caaccagaga tgctccacaa ggatatgctc cccacggttt tctttctaca atttccaaag    900

gttgcagatg tttttttgtg atgaatataa aattttattg tgtattactt ggtttcatta    960

aaattggtta act                                                       973


<210>  283
<211>  1091
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (58)..(58)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (834)..(834)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (860)..(860)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (885)..(885)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (887)..(887)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (902)..(902)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (910)..(910)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (943)..(943)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (954)..(954)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (961)..(961)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (967)..(967)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (975)..(975)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (999)..(999)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1009)..(1009)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1011)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1018)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1024)..(1024)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1026)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1034)..(1034)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1037)..(1037)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1046)..(1046)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1060)..(1061)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1067)..(1067)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1069)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1083)..(1083)
<223>  n is a, c, g, or t

<400>  283
aatagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttangt     60

gacactatag aatcgtcgac ccacgcgtcc ggccgcccgc ccggggtgtg gagcccggcc    120

gctgctcgcg ggctgagtgt ctgtcgctgc tgccgcctcc acccagcctc cgccatggac    180

ctcttcgggg acctgccgga gcccgagcgc tcgccgcgcc cggctgccgg gaaagaagct    240

cagaaaggac ccctgctctt tgatgacctc cctccggcca gcagtactga ctcaggatca    300

gggggacctt tgctttttga tgatctccca cccgctagca gtggcgattc aggttctctt    360

gccacatcaa tatcccagat ggtaaagact gaagggaaag gagcaaagag aaaaacctcc    420

gaggaagaga agaatggcag tgaagagctt gtggaaaaga aagtttgtaa agcctcttcg    480

gtgatctttg gtctgaaggg ctatgtggct gagcggaagg gtgagaggga ggagatgcag    540

gatgcccacg tcatcctgaa cgacatcacc gaggagtgta ggcccccatc gtccctcatt    600

actcgggttt catattttgc tgtttttgat ggacatggag gaattcgagc ctcaaaattt    660

gctgcacaga atttgcatca aaacttaatc agaaaatttc ctaaaggaga tgtaatcagt    720

gtagagaaaa accgtgaaga gatgcctttt ggacactttc aagcatactg atgaagagtt    780

tccttaaaca agcttccagc caaaaagcct gcctggaaaa gatgggtcca ctgnccacgt    840

gtgttctggc tgtaaacaan attctttata ttgccaacct cggananaag tccgggcaat    900

cntgtgttcn ttataatgag gaaaagtcaa aaacatgcag ccnttaaacc ctcnacaaaa    960

nagcatnaat cccanctcat tntnaaanag cggaatgang atacnnaang ntggaagnaa   1020

actncnggga tggnccntgt tttggncctg ctaaaaggtn ncccccncnn ttgggaaggg   1080

aantaaaacc c                                                        1091


<210>  284
<211>  1175
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (911)..(911)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (916)..(916)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (926)..(926)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (980)..(980)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1023)..(1023)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1026)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1030)..(1030)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1038)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1068)..(1068)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1072)..(1072)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1075)..(1076)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1082)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1095)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1099)..(1099)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1126)..(1127)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1156)..(1156)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1160)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1171)..(1172)
<223>  n is a, c, g, or t

<400>  284
naattagaga aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgatgctaa caacactgag aatagcacta    120

ctgtgaagaa ttctagtttg ttgagtggat tcagaggagg ttctagctac aaccatgaaa    180

cagagactat ctttgcatta ccaaggatgc agcttgactt taaatccatt catgttcaag    240

aaccacagga gccttcatta caggatgcca gcctgaagcc aaaagtagaa tgtagtgtgg    300

tgacagagtt cactgaccac atttgtgtga ctatggatgc tgagctcatc atgtttcttc    360

atgatttagt atcagcttat cttaaagaaa aagaaaaagc catctttcca cctcggattt    420

tatctactcg accaggacaa aaaagtccaa ttattataca tgacgacaat tcctctgata    480

aagatagaga agatagcatc acttatacta ctgtggactg gagagatttt atgtgcaata    540

catggcatct agaacctact cttagattaa tttcttggac tggaagaaag attgatccag    600

taggtgttga ttatattctt caaaaattgg gctttcatca tgctaggact actattccta    660

aatggcttca aagaggagtc atggatccac tggacaaggt tctgtcagtt cttatcaaaa    720

agctcggtac tgcactacag gatgaaaagg aaaagaaagg caaagacaaa gaagaacact    780

aaaaaagtaa tttgatctgt gaacaaatta tgattgtgtc tgttttatta cactggagtg    840

tttttttagt ataataattt gaaatataac tttaaaataa attctaaaat ttgtggctat    900

aattaaaaag ntttgnaagt taaccnggtt ctagttccat cattctgtgt accagngaag    960

tattgcatga taatggnaan ttttggggaa aaactanatt aaaaaaaata accgncttgn   1020

tanggnttan aattaaanaa ggggcaaaca attccggcnt ctttaaangc cngcnnaaaa   1080

cngggaattt tttnnttang gattggccgn aacttttaaa aaaaanntgg tgaagaaaag   1140

gggattttgg gggggncctn aattgctttt nnttt                              1175


<210>  285
<211>  1466
<212>  DNA
<213>  Homo sapiens

<400>  285
atgagcattc gtgttaccca gaaaagctat aaagttagca ccagcggtcc gcgtgcattt     60

agcagccgta gctatacctc tggtccgggt agccgtatta gcagcagcag ctttagccgt    120

gttggtagca gcaattttcg tggtggtctg ggtggtggtt atggtggtgc aagcggtatg    180

ggtggtatta ccgcagttac cgttaatcag agcctgctgt ctccgctggt tctggaagtt    240

gatccgaata ttcaggcagt tcgtacccag gaaaaagaac aaatcaaaac cctgaataat    300

aaatttgcca gctttattga taaagtgcgc tttctggaac agcagaacaa aatgctggaa    360

accaaatggt cattactgca gcagcaaaaa accgcacgta gcaatatgga taatatgttt    420

gaaagctata ttaacaatct gcgtcgtcag ctggaaaccc tgggtcagga aaaactgaaa    480

ctggaagccg aactgggtaa tatgcagggt ctggtggaag attttaaaaa caagtacgaa    540

gatgaaatta ataaacgcac cgaaatggaa aatgaatttg tgctgattaa aaaagatgtg    600

gatgaagcct atatgaacaa agtggaactg gaaagccgtc tggaaggtct gaccgatgaa    660

attaactttc tgcgccagct gtatgaagaa gaaattcgcg aactgcagag ccagattagc    720

gataccagcg ttgttctgag catggataat agccgtagcc tggatatgga tagcattatc    780

gccgaagtta aagcccagta tgaagatatt gcaaatcgta gccgtgcaga ggcagaaagc    840

atgtatcaga tcaaatatga agaactgcag tctctggcag gtaaacatgg tgatgatctg    900

cgtcgtacca aaaccgaaat cagcgaaatg aatcgcaata ttagccgtct gcaggcagaa    960

attgaaggtc tgaaaggtca gcgtgcaagc ctggaagcag caattgcaga tgcagaacag   1020

cgtggtgaac tggcaattaa agatgccaat gccaaactga gcgaactgga agcagccctg   1080

cagcgtgcaa aacaggatat ggcacgtcag ctgcgtgaat atcaagaact gatgaacgtt   1140

aaactggccc tggatattga aattgccacc tatcgtaaac tgctggaagg tgaagaatct   1200

cgtctggaaa gcggtatgca gaatatgagc attcatacca aaaccacctc tggttatgcc   1260

ggtggtctga gcagcgcata tggtggtctg acctctccgg gtctgagcta tagcctgggt   1320

agcagctttg gtagcggtgc aggtagcagc tcttttagcc gtaccagcag cagccgtgca   1380

gttgttgtga aaaaaattga aacccgtgat ggtaaactgg ttagcgaaag ctctgatgtt   1440

ctgccgaaat aagcggccgc gagctc                                        1466


<210>  286
<211>  912
<212>  DNA
<213>  Homo sapiens

<400>  286
actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga cactatagaa     60

tcgtcgaccc acgcgtccgg tgctcctgag ccctccacca tcgcccgctc tctaccaacc    120

actgtcccag agtcaccaaa ctaccgcaac accaggaccc ctcgcactcc ccggacacca    180

cagctcaaag actcaagcca gacatcacgg ttttacccag tggtgaaaga aggacggaca    240

ctggatgcca agatgcctcg aaaaagaaag acaagacaca gttcaaaccc acccttggag    300

agccatgtgg gctgggtgat ggattcccgt gagcacaggc cccgtactgc ttccatcagc    360

tccagcccct cagaagggac gcctacagtt ggcagctatg gctgtacccc tcagtcattg    420

cccaagttcc agcatccttc ccatgaactg ctcaaggaaa atggcttcac acaacacgtc    480

taccataagt atcgtaggcg ctgccttaat gagcggaaac gcttgggcat tggccagtct    540

caggagatga acacactctt ccgcttctgg tccttcttcc tccgagatca cttcaacaaa    600

aagatgtatg aggagttcaa gcagctggct ctggaggacg ccaaagaagg ctacagatat    660

ggtttggagt gcctttttcg atactacagt tatggcctgg aaaagaagtt ccggctggac    720

atattcaagg attttcagga ggaaacggtg aaggactatg aagctggcca actgtatggg    780

ctggagaagt tctgggcctt cttgaaatat tccaaagcca aaaatttgga cattgacccc    840

aaactgcaag aatacctcgg caaattccga cgtcttgaag acttccgagt agatcccccc    900

atgggtgagg ag                                                        912


<210>  287
<211>  1327
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (858)..(858)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (928)..(928)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (944)..(944)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (972)..(972)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (995)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1009)..(1009)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1011)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1014)..(1014)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1044)..(1044)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1065)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1085)..(1085)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1090)..(1090)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1094)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1119)..(1119)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1127)..(1127)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1129)..(1129)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1136)..(1136)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1142)..(1142)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1154)..(1154)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1156)..(1156)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1166)..(1166)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1168)..(1168)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1172)..(1172)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1177)..(1177)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1180)..(1180)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1185)..(1186)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1197)..(1198)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1207)..(1207)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1219)..(1219)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1228)..(1228)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1230)..(1230)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1242)..(1242)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1249)..(1250)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1257)..(1258)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1261)..(1261)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1267)..(1267)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1275)..(1275)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1284)..(1284)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1290)..(1291)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1314)..(1316)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1322)..(1322)
<223>  n is a, c, g, or t

<400>  287
aatagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gatgtaaagt tagccctgga catggaaatc    120

agtgcttaca ggaaactctt agaaggcgaa gaagagaggt tgaagctgtc tccaagccct    180

tcttcccgtg tgacagtatc ccgagcatcc tcaagtcgta gtgtacgtac aactagagga    240

aagcggaaga gggttgatgt ggaagaatca gaggcgagta gtagtgttag catctctcat    300

tccgcctcag ccactggaaa tgtttgcatc gaagaaattg atgttgatgg gaaatttatc    360

cgcttgaaga acacttctga acaggatcaa ccaatgggag gctgggagat gatcagaaaa    420

attggagaca catcagtcag ttataaatat acctcaagat atgtgctgaa ggcaggccag    480

actgttacaa tttgggctgc aaacgctggt gtcacagcca gccccccaac tgacctcatc    540

tggaagaacc agaactcgtg gggcactggc gaagatgtga aggttatatt gaaaaattct    600

cagggagagg aggttgctca aagaagtaca gtctttaaaa caaccatacc tgaagaagag    660

gaggaggagg aagaagcagc tggagtggtt gttgaggaag aacttttcca ccagcaggga    720

accccaagag catccaatag aagctgtgca attatgtaaa attttcaact gtcttcctca    780

aaataaagaa gtatggtaat ctttacctgt atacagtgca gagccttctc agaagcacag    840

aatattttta tatttccntt atgtgaaatt ttaagctgca aatctgatgg ccttaatttc    900

ctttttgaca ctgaaagttt tgtaaaanaa atcatgtcca tacnctttgt tgcaagatgt    960

gaattattga cnctgaacta ataactgtgt actgntcgga aggggtccnc naantttttg   1020

acttttttgg aggggggttt ttcntttttt taagtcttat gaggngggag ggtaataacc   1080

cctgngcgcn tggngtattt gaaattgccc ctctaaacna catcctntnt tttccngtaa   1140

tnaaaacggg ggtngngggg gggaancntt tncaaantgn acttnnacga atttctnnaa   1200

aacaccnggt taatttttna aaaaattntn aaggaattac cnccccggnn cccgggnngg   1260

ncccaantgg tttgnttttt cttntttttn nggggggggg gggggggggg gtcnnnaaac   1320

cngtttt                                                             1327


<210>  288
<211>  1046
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (809)..(809)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (885)..(885)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (931)..(931)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (934)..(934)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (945)..(945)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (963)..(963)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (980)..(980)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (993)..(993)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1002)..(1002)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1016)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1021)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1027)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1029)..(1029)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1037)..(1037)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1039)..(1039)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1041)..(1041)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1043)..(1043)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1045)..(1045)
<223>  n is a, c, g, or t

<400>  288
aaatagagaa attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cgcagaaaga gccaggatga agggaggaga    120

gaagataggt attgcggagt ttgccgcctc cctggaagtc cccgtttctg acttgctgga    180

agacatgttt tcactgttcg acgagagcgg cagcggcgag gtggacctgc gagagtgtgt    240

ggttgccctg tctgtcgtct gccggccggc ccggaccctg gacaccatcc agctggcttt    300

caagatgtac ggagcgcaag aggacggcag cgtcggcgaa ggtgacctgt cctgcatcct    360

caagacggcc ctgggggtgg cagagctcac cgtgaccgac ctattccgag ccattgacca    420

agaggagaag gggaagatca cattcgctga cttccacagg tttgcagaaa tgtaccctgc    480

cttcgcagag gaatacctgt acccggatca gacacatttc gaaagctgtg cagagacctc    540

acctgcgcca atcccaaacg gcttctgtgc cgatttcagc ccggaaaact cagacgctgg    600

gcggaagcct gttcgcaaga agctggatta ggacccaggg ttgcggagag acgcggcccc    660

tcccgcgtgg acatcaccgc catgagcctc tttgcgagtg acctctgggc tccgctcctc    720

actcctgctg tacaggcact gtcttcagcc cgagttccag gggcctcggg ggctgtttgt    780

atcttgttcc tttgtgaagt gtgttgcana accgacgctt actgtgcgag aatcggaggg    840

cgcgcacgcg gatcccccgc ctggcctgga ccccgtgggg gtcangttcc ctgcccgggg    900

cggggggggc acccggtgcc cgcccccgtg nttntcccac ggggnccctg gtttcnaagt    960

ctntgtcaca agccttttcn ggcggccagc gtngcaccgg gnggggcctt ccgtgncaan   1020

ntcaannana nncctgncna nananc                                        1046


<210>  289
<211>  1114
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (653)..(653)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (692)..(692)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (709)..(709)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (712)..(712)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (745)..(745)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (764)..(764)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (771)..(771)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (782)..(782)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (796)..(796)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (817)..(817)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (822)..(822)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (846)..(846)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (860)..(861)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (881)..(881)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (884)..(884)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (886)..(887)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (898)..(898)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (905)..(905)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (929)..(929)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (939)..(939)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (943)..(943)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (951)..(951)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (965)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (979)..(979)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1008)..(1009)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1022)..(1023)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1030)..(1030)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1041)..(1041)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1055)..(1055)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1057)..(1057)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1064)..(1064)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1074)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1077)..(1079)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1082)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1086)..(1089)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1092)..(1092)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<400>  289
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc caaaaaggtc agccatgtgg ctgatacaaa    120

ggtcaataca aaggctcagg agactgaggc tgcaccctct caggccccag cagatgaacc    180

tgagcctgag agtgcagctg cccagtctca ggagaatcag gatactcggc ccaaggtcaa    240

agccaagaaa gcccgaaagg tgaagcatct ggatggggaa gaggatggca gcagtgatca    300

gagtcaggct tctggaacca caggtggccg aagggtctca aaggccctaa tggcctcaat    360

ggcccgcagg gcttcaaggg gtcccatagc cttttgggcc cgcagggcat caaggactcg    420

gttggctgct tgggcccgga gagccttgct ctccctgaga tcacctaaag cccgtagggg    480

caaggctcgc cgtagagctg ccaagctcca gtcatcccaa gagcctgaag caccaccacc    540

tcgggatgtg gcccttttgc aagggagggc aaatgatttg gtgaagtacc ttttggctaa    600

agaccagacg aagattccca tcaagcgctc ggacatgctg aaggacatca tcnaagaata    660

cactgatgtg taccccgaaa tcattgaacg ancaggctat tccttggana angtatttgg    720

gattcaattg aaggaaattg ataanaatga ccacttgtac attncttctc nccaccttaa    780

ancccactga tgcagncata ctgggaaacg actaagnact cnccccaagc tgggtctgct    840

catggngctt cttaacatcn ntcttcatga aagggaaatc ngtncnntga ggctgtcntt    900

ttggnaagtg cttcccaaat ttggggctnc ccccctggna aanatcattc nctcttttgg    960

ggaannggaa aaaacctcnt cnctggatga attttttaaa caaaaaannc cctggaatta   1020

tnnccaaaan tccccaaaaa naatcccccc tgaananaaa tttntttttg gggnccnnnc   1080

cncttnnnnt tnaaancncc aaaaaaaaan tcct                               1114


<210>  290
<211>  839
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (471)..(471)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (495)..(495)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (543)..(543)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (550)..(550)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (567)..(567)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (583)..(583)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (610)..(610)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (634)..(634)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (649)..(649)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (656)..(656)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (694)..(695)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (701)..(701)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (708)..(708)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (717)..(717)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (721)..(721)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (723)..(723)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (727)..(727)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (731)..(731)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (760)..(760)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (770)..(770)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (788)..(789)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (794)..(794)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (797)..(797)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (802)..(802)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (811)..(811)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (814)..(814)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (826)..(826)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (829)..(829)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (831)..(832)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (834)..(834)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (839)..(839)
<223>  n is a, c, g, or t

<400>  290
nnatagagaa attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cgccgagacc cccagtgacg ccgcagccat    120

ggagagcggc ccgcgtgcgg agctgggggc gggcgcaccc ccagctgtgg tcgccaggac    180

ccccccagag ccaagacctt ctccagaagg tgacccttcc cccccaccac caccaatgtc    240

agccctggtc cccgacactc ccccggacac ccctcctgcc atgaagaatg ccactagctc    300

taagcagctc ccactggaac cagagagccc ctcagggcag gtcgggccta ggccagcccc    360

cccgcaggaa gagtcccctt cctctgaagc aaagagcaga ggacccaccc caccagccat    420

gggcccacgg gatgccagac ctcctcgaag gagcagccag ccatctccaa nagcagtgcc    480

agcctccgac agccntccca ccaagcaaga ggtgaagaag gcaggagaga gacacaagct    540

ggnaaaggan cggcgagaag agcgggncaa gtacctggcg gcnaagaagg cagtgtggct    600

ggagaaggan gagaaggcca aggcgctgcg gganaagcag ctccagganc gccggngccg    660

gctggaggag caacgtctta aagccgagca agcnntgcag ncctgtanga acggcancgg    720

nanaagnttc nagaaaaaca atggatcgct atgaaagcan ccattccaan ggtcagtgaa    780

aaaagacnnt gggncgnaat tncggcaaca ncgnctggtc ctgggnagng nncncttgn     839


<210>  291
<211>  801
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (752)..(752)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (789)..(789)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (798)..(798)
<223>  n is a, c, g, or t

<400>  291
nanctntgag aggatcgcat caccatcacc atcacggatc ctatttaggt gacactatag     60

aatcgtcgac ccacgcgtcc gcccacgcgt ccggtaacat tgtagtcaag tctgattgca    120

cattgaaaat cctggacttt ggactggcca ggacagcagg cacaagcttc atgatgactc    180

catatgtggt gacacgttat tacagagccc ctgaggtcat cctggggatg ggctacaagg    240

agaacgtgga tatatggtct gtgggatgca ttatgggaga aatggttcgc cacaaaatcc    300

tctttccagg aagggactat attgaccagt ggaataaggt aattgaacaa ctaggaacac    360

catgtccaga attcatgaag aaattgcaac ccacagtaag aaactatgtg gagaatcggc    420

ccaagtatgc gggactcacc ttccccaaac tcttcccaga ttccctcttc ccagcggact    480

ccgagcacaa taaactcaaa gccagccaag ccagggactt gttgtcaaag atgctagtga    540

ttgacccagc aaaaagaata tcagtggacg acgccttaca gcatccctac atcaacgtct    600

ggtatgaccc agccgaagtg gaggcgcctc cacctcagat atatgacaag cagttggatg    660

aaagagaaca cacaattgga agaatggaaa gaacttatct acaagggaag taatgaattc    720

agaagaaaag actaaaaatg gtgtagtaaa anggacagcc tttctccttc agcacaggtg    780

cagcagtgna acagcagngg a                                              801


<210>  292
<211>  817
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (803)..(803)
<223>  n is a, c, g, or t

<400>  292
cttaagagga gaattaacta tgagaggatc gcatcaccat caccatcacg gatcctattt     60

aggtgacact atagaatcgt cgacccacgc gtccgcggac gcgtgggcag tgaacgtata    120

ctcaacgtca gtgaccagtg ataacctaag tcgacatgac atgctggcct ggatcaatga    180

gtctctgcag ttgaatctga caaagatcga acagttgtgc tcaggggctg cgtattgtca    240

gtttatggac atgctgttcc ctggctccat tgccttgaag aaagtgaaat tccaagctaa    300

gctagaacac gagtacatcc agaacttcaa aatactacaa gcaggtttta agagaatggg    360

tgttgacaaa ataattcctg tggacaaatt agtaaaagga aagtttcagg acaattttga    420

attcgttcag tggttcaaga agtttttcga tgcaaactat gatggaaaag actatgaccc    480

tgtggctgcc agacaaggtc aagaaactgc agtggctcct tcccttgttg ctccagctct    540

gaataaaccg aagaaacctc tcacttctag cagtgcagct ccccagaggc ccatctcaac    600

acagagaacc gctgcggctc ctaaggctgg ccctggtgtg gtgcgaaaga accctggtgt    660

gggcaacgga gacgacgagg cagctgagtt gatgcagcag gtcaacgtat tgaaacttac    720

tgttgaagac ttggagaaag agagggattt ctacttcgga aagctacgga acattgaatt    780

gatttgccag gagaacgagg ggnaaaacga ccctgta                             817


<210>  293
<211>  1256
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (810)..(810)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (843)..(843)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (865)..(865)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (868)..(868)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (873)..(873)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (891)..(891)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (915)..(915)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (926)..(926)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (932)..(932)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (934)..(935)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (941)..(941)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (945)..(945)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (947)..(947)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (960)..(960)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (970)..(970)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (979)..(979)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (986)..(986)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (993)..(993)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1008)..(1008)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1019)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1023)..(1023)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1049)..(1049)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1054)..(1055)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1068)..(1068)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1084)..(1086)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1114)..(1115)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1123)..(1124)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1138)..(1138)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1146)..(1146)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1153)..(1153)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1155)..(1155)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1163)..(1164)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1187)..(1188)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1196)..(1196)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1207)..(1207)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1216)..(1216)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1229)..(1229)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1243)..(1244)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1253)..(1253)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1256)..(1256)
<223>  n is a, c, g, or t

<400>  293
naattagaga aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccggctctgg tgaacctcca aaatcagggg    120

atcgcagcgg ctacagcagc cccggctccc caggcactcc cggcagccgc tcccgcaccc    180

cgtcccttcc aaccccaccc acccgggagc ccaagaaggt ggcagtggtc cgtactccac    240

ccaagtcgcc gtcttccgcc aagagccgcc tgcagacagc ccccgtgccc atgccagacc    300

tgaagaatgt caagtccaag atcggctcca ctgagaacct gaagcaccag ccgggaggcg    360

ggaaggtgca aatagtctac aaaccagttg acctgagcaa ggtgacctcc aagtgtggct    420

cattaggcaa catccatcat aaaccaggag gtggccaggt ggaagtaaaa tctgagaagc    480

ttgacttcaa ggacagagtc cagtcgaaga ttgggtccct ggacaatatc acccacgtcc    540

ctggcggagg aaataaaaag attgaaaccc acaagctgac cttccgcgag aacgccaaag    600

ccaagacaga ccacggggcg gagatcgtgt acaagtcgcc agtggtgtct ggggacacgt    660

ctccacggca tctcagcaat gtctcctcca ccggcagcat cgacatggta gactcgcccc    720

cagctcgcca cgctagctga cgaggtgtct gcctccctgg ccaagcaggg tttgtgatca    780

ggcccctggg ggcggtcaat aattgtggan aggaaaaaat gaaaaagtgt ggaaaaaaaa    840

aanaataatg gaccggggcc cccgnccntt tgnccccagg ttgctcctcg naattcggtt    900

aaattggtta aaccncttaa acctgntttt tntnnctcgg ntttngnctc gggaanttcn    960

aaatcngtgn gtggggaana aaaaanaaat ttnttttttt ccaaantnga agggngggnn   1020

tantaataaa aaatttttta aaaaaaaant tttnnaaaaa attggccnat tccaaaattt   1080

tccnnnggga aatccctttt taaatttttt tttnntcccc ccnncggtaa aaaaaggnaa   1140

aaaaanaaaa gtntntaaaa ttnntttttg ggggaatttt aaggggnngg ggggtnccaa   1200

acccccntgg ggcctnttgg ggggggttnc aaaaaggggg ggnnaaaaaa aanatn       1256


<210>  294
<211>  1122
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (826)..(826)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (882)..(882)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (887)..(887)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (900)..(900)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (911)..(911)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (919)..(919)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (923)..(923)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (942)..(942)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (952)..(952)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (962)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1003)..(1003)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1012)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1022)..(1022)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1028)..(1028)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1032)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1037)..(1037)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1061)..(1061)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1065)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1073)..(1074)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1077)..(1077)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1082)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1088)..(1088)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1092)..(1092)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1095)..(1095)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1103)..(1103)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1112)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1117)..(1117)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1120)..(1121)
<223>  n is a, c, g, or t

<400>  294
agagaattaa ctatgagagg atcgcatcac catcaccatc acggatccta tttaggtgac     60

actatagaat cgtcgaccca cgcgtccgcc ctgctccaca ccagccgcag cctttcttcc    120

cttaaccgct ccttgtcatc aggggagagt gggccaggct ctcccacaca cagccacagc    180

ctttcccccc gatctcccac tcaaggctac cgggtgaccc ccgatgctgt gcattcagtg    240

ggagggaatt catcacagag cagctccccc agctccagcg tgcccagttc cccagccggc    300

tctgggcaca cacggcccag ctccctccac ggtctggcac ccaagctcca acgccagtac    360

cgctctccac ggcgcaagtc agcaggcagc atcccactgt caccactggc ccacacccct    420

tctcccccac ccccaacagc ttcacctcag cggtccccat cgcccctgtc tggccatgta    480

gcccaggcct ttcccacaaa gcttcacttg tcacctcccc tgggcaggca actctcacgg    540

cccaagagtg cggagccacc ccgttcacca ctactcaaga gggtgcagtc ggctgagaaa    600

ctggcagcag cacttgccgc ctctgagaag aagctagcca cttctcgcaa gcacagcctt    660

gacctgcccc actctgaact aaagaaggaa ctgccgccca gggaagtgag ccctctggag    720

gtagttggag ccaggagtgt gctgtctggc aagggggccc tgccagggaa gggggtgctg    780

cagcctgctc cctcacgggc cctaggcacc ctccggcagg accganccga acgacgggag    840

tcgctgcaaa acaagaagcc attcgtgagg tggactcctc anaggangac accgaggaan    900

ggcctgaaaa nagccaggng canaggaact gaacttggca cntcacccaa antganccaa    960

anggggccct aaaggaacag gaaaaaantg ggaaaaagaa tcntttccgt nnaaaaacct   1020

angaaccngg gnccaanggn ccaagcctat tgaaagggat naaantgggg gcnnccnaaa   1080

anggaaantc cnagnggtcc canaggaggn tnggganccn na                      1122


<210>  295
<211>  1075
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (852)..(852)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (855)..(855)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (885)..(885)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (899)..(899)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (941)..(941)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (943)..(943)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (950)..(950)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (958)..(958)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (964)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (969)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (972)..(972)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (974)..(974)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (993)..(993)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1002)..(1002)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1007)..(1007)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1010)..(1010)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1013)..(1013)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1026)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1033)..(1033)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1047)..(1047)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1058)..(1058)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1061)..(1061)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1073)..(1073)
<223>  n is a, c, g, or t

<400>  295
agagagaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccga gagccgccag cgcgtgcgct acgactcctc    120

caaccaggtc aagggcaagc ccgacctgaa cacggcgctg cccgtgcgcc agacggcgtc    180

catcttcaag cagccggtga ccaagattac caaccacccc agcaacaagg tcaagagcga    240

cccgcagaag gcggtggacc agccgcgcca gctcttctgg gagaagaagc tgagcggcct    300

gaacgccttc gacattgctg aggagctggt caagaccatg gacctcccca agggcctgca    360

gggggtggga cctggctgca cggatgagac gctgctgtcg gccatcgcca gcgccctgca    420

cactagcacc atgcccatca cgggacagct ctcggccgcc gtggagaaga accccggcgt    480

atggctcaac accacgcagc ccctgtgcaa agccttcatg gtgaccgacg aggacatcag    540

gaagcaggaa gagctggtgc agcaggtgcg gaagcggctg gaggaggcgc tgatggccga    600

catgctggcg cacgtggagg agctggcccg tgacggggag gcgccgctgg acaaggcctg    660

cgctgaggac gacgacgagg aagacgagga ggaggaggag gaggagcccg acccggaccc    720

ggagatggag cacgtctagg gcagaggccc tgccgagagc ccgtgctgcc tgctggagcc    780

gcctgcagac gcggtcctcg gccccacgtg aaccaggctc ggcggcgaag cccagccttg    840

gagacaccca gnagnaaggc cgtgctcctg gcttccttcc tcggnccgtc ccacttccng    900

gggcctcggg gcacacagct ggggctgccc ccacccgaaa nancctccan gctcgtcntc    960

taanantcng gntncggaaa tgccgggtgc tcntggncct gnctggntcn tananctttg   1020

ggctcnaggc cantcctccc atgcccnttt tccacttntt naaatggaan aanca        1075


<210>  296
<211>  864
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (549)..(549)
<223>  n is a, c, g, or t

<400>  296
gggattacta tgagaggtcg catcaccatc accatcacgg atcctattta ggtgacacta     60

tagaatcgtc gactctggac cttggctgtc actcagttac caacattgac ttcttactca    120

acctgtctgg ccacccagag tttgaagctg ggaacgtgca cactgatttc acccctcaac    180

accacaaaca gttgttgctc agtcggaagg ctgcagccaa agagccttta tgccaggcag    240

ccctgggtct catcctcaag gagaaagcca tgaccgacac tttcactctt caggcacatg    300

atcaattctc tccattttcg tctagcagtg gaagaagact gaatatctcg tataccagaa    360

acatgactct taaagatggt aaaaacaatg tagccatagc tgtaacgtat aaccatgatg    420

ggtcttatag catgcagatt gaagataaaa ctttccaagt ccttggtaat ctttacagcg    480

agggagactg cacttacctg aaatgttctg ttaatggagt tgctagtaaa gcgaagctga    540

ttatcctgna aaacactatt tacctatttt ccaaggaagg aagtattgag attgacattc    600

cagtccccaa atacttatct tctgtgagct cacaagaaac tcagggcggc cccttagctc    660

ctatgactgg aaccattgaa aaggtgtttg tcaaagctgg agacaaagtg aaagcgggag    720

attccctcat gggtatgatc gccatgaaga tggagcatac cataaagtct caaaggatgg    780

cacagtaaag aaagtgttct acagaaaagt gctcaggcca acgacacact ctttagtcca    840

gtggaggagg aaaatcaacc aagg                                           864


<210>  297
<211>  976
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (814)..(814)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (833)..(833)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (866)..(866)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (904)..(904)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (933)..(933)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (937)..(937)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (945)..(945)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (948)..(948)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (952)..(952)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (957)..(959)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (965)..(976)
<223>  n is a, c, g, or t

<400>  297
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc aggagccacc tgtaacctgg attgcagaag    120

gggccagttt gggcccagct gcaccctgca ctgtgactgc gggggtgggg ctgactgcga    180

ccctgtcagt gggcagtgtc actgtgtgga tggctacatg gggcccacgt gccgggaagg    240

tgggcccctc cggctccccg agaacccgtc cttagcccag ggctcagcgg gcacactgcc    300

cgcctccagc agacccacat cccggagcgg tggaccagcg aggcactagt agaggcagtc    360

ccgtggagcc cgcctctcca gtcccagcca gaggggaccc tggcctttgg tgaccactga    420

gaaggacact tcacgggccc agagctcctg gtactgccct tcctttgagg gccgtggagg    480

gctgtggaca gcccagcaac ctgtcgctct tggaggctgg tgtggccttg aggagggaag    540

cctcgcatgg ccgctggaag agaggcgcct cctggcctgg ctctgcagaa cccaggggca    600

cgctctgggc ctgggctgag gaagtcccgc tctccccgcg gctctgagtt ggactgagga    660

caggtgtggg cgccagtgtg ggtgcaggcg caggtgcagg cacagggcca ctgtcctcca    720

ggcaggcttt ttggtgctag gccctgggac tggaagtcgc ccagcccgta tttatgtaaa    780

ggtatttatg ggccactgca catgcccgct gcanccctgg gatcagctgg aanctgcctg    840

tcatctcctg cccaatcccc aaaaanccct gattcaggtc tgcaggctcc tgcgggctca    900

ccangctgct ggctccggta catgtaaacc tangaangta aagancangc ancctcnnna    960

aaaannnnnn nnnnnn                                                    976


<210>  298
<211>  1269
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (826)..(826)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (852)..(852)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (854)..(854)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (877)..(877)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (880)..(880)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (901)..(901)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (948)..(948)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (974)..(974)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (986)..(986)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1007)..(1007)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1011)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1013)..(1013)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1023)..(1023)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1031)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1054)..(1054)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1056)..(1056)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1062)..(1062)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1064)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1080)..(1081)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1089)..(1089)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1093)..(1093)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1099)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1113)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1129)..(1129)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1137)..(1137)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1139)..(1139)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1147)..(1147)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1151)..(1151)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1154)..(1154)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1156)..(1156)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1165)..(1165)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1171)..(1171)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1190)..(1190)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1199)..(1199)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1204)..(1205)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1212)..(1213)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1222)..(1222)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1240)..(1241)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1248)..(1248)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1256)..(1256)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1259)..(1259)
<223>  n is a, c, g, or t

<400>  298
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc ttcagcagca agagcagcag ctccagcaac    120

tccagcagct cctggcctcc ccgcagctga ccccggaaca ccagactgtt gtctaccaga    180

tgatccagca gatccagcag aaacgggagc tgcagcgcct gcagatggct gggggctccc    240

agctgcccat ggccagcctg ctggcaggaa gctccacccc gctgctgtct gcgggtaccc    300

ctggcctgct gcccacagcg tctgctccac ccctgctgcc cgctggagcc ctagtggctc    360

cctcgcttgg caacaacaca agtctcatgg ccgcagcagc tgcagctgca gcagtagcag    420

cagcaggcgg acctccagtc ctcactgccc agaccaaccc cttcctcagc ctgtcgggag    480

cagagggcag tggcggtggc cccaaaggag ggaccgctga caaaggagcc tcagccaacc    540

aggaaaaagg ctaaatccac ccttacccct cctgaccccc ccaagtggag ggaacagatc    600

ctggcctgag gggtcctagc ctggagcagg cgcctgcgcc cagaccctgg agagccttga    660

cccagagcct gtgctgaggt ccagggagtg tggagagctc ctggtgtcga ggactgagac    720

tgagagggga gccccctcca tctggccccc ttccctttcc gcactgtccg ctttgtgagg    780

ctcagaggaa ggacagtctg caagcccgcc taggaggtcc atcccnagca aatgttttgg    840

aggtcccccc ananagcaaa gtgggccatg gcaaaantan ggggttggtt ggacctgtca    900

natgaaaatg gatcagcact ttgaatggga aaaattggaa ggaaaagncc ttggcctgtc    960

cctgcgggga aatnttttat ggaaanaagg gctgganccc actttanctg nanttttttn   1020

ccnacttggg naaaatggaa aaaggaaccc ttgnantttt tntnncatcc cccccccagn   1080

naaggggcna aanttgannt tttaaaaacc cnnaaatttt gggggctgna aaagggnang   1140

aaaaaantaa nttnanccca gcctnttaaa nttttgggcc ccttaaaggn aaaaaaggna   1200

aggnngggaa anntttgcct tntttgggcc cccctttttn ncaattgnaa ataaangcna   1260

aaggggaaa                                                           1269


<210>  299
<211>  1380
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (8)..(11)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<400>  299
aatgaatnnn nggatatact gacttaccta taaataggcg tatccgaggc cctttcgtct     60

tcacctcgag aaatcataaa aaatttattt gctttgtgag cggataacaa ttataataga    120

ttcaattgtg agcggataac aatttcacac agaattcatt aaagaggaga aattaactat    180

gagaggatcg catcaccatc accatcacgg tcgacccacg cgtccgccca cgcgtccggc    240

cgagagaaag acaaagttgt ccaagaatct gctgcgcatg aagtttatgc aaaggggact    300

ggactcagaa accaagaaac aactagaaga agaagaaaag aaaatcatta gtgaagagca    360

ctggtacttg gatttgccag agcttaaaga gaaagagagt ttcataatag aagagcagag    420

tttcttacta tgtgaagatc ttctctatgg aagaatgtca ttcagaggat ttaatcctga    480

ggttgagaaa ttgatgcttc agatgaatgc taagcacaaa gcagaagaag ttgaagatga    540

aacagtagag cttgatgtgt cagatgaaga gatcggccgc gatccgcatg cgagctcgat    600

tagctgagct tggactcctg ttgatagatc cagtaatgac ctcagaactc catctggatt    660

tgttcagaac gctcggttgc cgccgggcgt tttttattgg tgagaatcca agctagcttg    720

gcgagatttt caggagctaa ggaagctaaa atggagaaaa aaatcactgg atataccacc    780

gttgatatat cccaatggca tcgtaaagaa cattttgagg catttcagtc agttgctcaa    840

tgtacctata accagaccgt tcagctggat attacggcct ttttaaagac cgtaaagaaa    900

ataagcacaa gttttatccg gccttatcac attcttggcc gcctgatgat gctcatccgg    960

atttcnttgg caatgaaaga cgggacctgg gatatgggaa aaggttcccc ttgttacccc   1020

gttttcccga acaaactgaa cgttttcccc cctggaagga ataccccgac atttccgggg   1080

ttcctcccat atattcccaa ataggggcgg tctacggtaa ccccctcctt ttccctaagc   1140

accatccgaa aataattttc cctccaccca cccccgggag atttacccat tttcttacac   1200

ttgtcctacg tgcaacactc tccccctatt tcccgatggc ctaaataata acgcgatagg   1260

ttccacacta cgccaacatt ggacctccta ccttcctctc acaatttgcc ctttacccaa   1320

ccattccacc tacaagtcgc tctgtagcat catctgaact acacgcccct ctatgccaca   1380


<210>  300
<211>  877
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (848)..(849)
<223>  n is a, c, g, or t

<400>  300
agaattacta tgagaggtcg catcaccatc accatcacgg atcctattta ggtgacacta     60

tagaatcgtc gactctggac cttggctgtc actcagttaa aaaggaaaat acgaaaaaag    120

acttgttagg cattattaag ggcatgaaag ttgaattaag cacagtaaat gtacgaacaa    180

caaagccccc caaaagaaga ccacttaaaa gtttggaagc tacacttggc aggcttcgaa    240

gagctacaga atatgctcca aagaagagaa ttgagcccct gagtcctgag ttggtggcag    300

ctgcatctgc tgtggcaggt tctctccctt ttgataagca aacaaccaag tcagagctgc    360

tgagccagct ccagcagcat gaggaagagt caagggcaca gagagatgca aagcgaccta    420

aaatcagttt cagtaacata atatcagata tgaaagttgc cagatctgct acagctagag    480

ttcgttcaag accagagctt cggattcagt ttgatgaagg ctatgacaat tatcctggcc    540

aggagaagac ggatgatctt aaaaaaagga aaaatatatt cacagggaaa agacttaata    600

tttttgacat gatggcagtt actaaagaag cacctgaaac agacacatca ccttcacttt    660

gggatgtgga atttgctaag cagttagcca cagtaaatga acaacccctt cagaatggat    720

ttgaagagct gatccagtgg acaaaagagg ggaaactatg ggagtttcca ttttacatga    780

gcaggtttga tgatgatggt cagaattcat gacatatatt ctggagaaca ctgagagctt    840

tcaaacanng acatcgcatt catgagctgt gactgtg                             877


<210>  301
<211>  1238
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (753)..(753)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (852)..(852)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (870)..(870)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (878)..(878)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (893)..(893)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (899)..(899)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (909)..(909)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (954)..(954)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (971)..(971)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (990)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (995)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1003)..(1003)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1024)..(1025)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1033)..(1033)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1037)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1044)..(1044)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1046)..(1046)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1057)..(1057)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1082)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1087)..(1087)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1092)..(1092)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1102)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1105)..(1105)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1113)..(1115)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1123)..(1123)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1127)..(1127)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1151)..(1152)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1154)..(1154)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1184)..(1184)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1197)..(1197)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1201)..(1201)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1203)..(1203)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1210)..(1210)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1227)..(1227)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1231)..(1231)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1234)..(1234)
<223>  n is a, c, g, or t

<400>  301
attagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gttaaggtga aaagcactga agttgagatc    120

ctagagaagt ctcaaattga agccattgct tcctcgttag cctcacagaa tgaggttcct    180

gcggcacccc tggaagaact ggcctacaga cggtcgcttc gcgtggctct ggacgttctg    240

agcgagggct cgatttggag tcaagaaagc tctgcaggga caggtagagc tgaccggtct    300

ctgcgaggga agcccatgga gcatgtctcc tcgccctgtg attcgaactc ctcatctctt    360

ccccgcggag acgtgttggg cagttccaga cctcacagga ggaggccatg tgtgcaacaa    420

agcctgtcaa tttcgttcac ttgtgaaaag gaccccgagt gcaaagtgga ccacaagaag    480

gggctcagga aaagtgaaaa cccaagaggc ccgttggtcc tcccagctgg aggtggtgcc    540

caagatgaga gtgggtccag aatccaccac aaaaattgga ctcttgcaag taagagggga    600

agaaactcag cgcagaaggc tagcttgtgc ctgaatggat cttccctttc agaggacgac    660

acggagagag acatggggag caaaggaggc agctgggcag ccccgtcctt gccctccggg    720

gtcagggagg acgatccctg tgccaacgct ganggacacg accccggtct gccgttgggc    780

agcctcactg cgcccccagc ccctgagccc tcggcctgct caaagcctgg agaatgccct    840

gcgaaaaaag angccgcgcc tggatggcan ccaaaagncc gcctgccgtg canctgganc    900

ccatggcanc aggggccgca ccatcccccg ggccggggcc agggcccaaa aaantctgtg    960

accccncgca ncacccnccc gggntggggn cccgncttcc ctnccnaagc cttttggggg   1020

aatnnaaaca aantntnntt tccntngccc ggaattncca aaaaacttgg aaaaaaaaat   1080

gncccantct tnccaaaaaa anccnagggg gtnnnaaatt ccnatgnggt ttctatcctg   1140

ggaggaaaaa nnanggaaaa accaaggaac ccccccaaaa ttcnttttta aaccccnaaa   1200

ncnccttttn tttttaaaaa aaaaatntta nttntggc                           1238


<210>  302
<211>  1384
<212>  DNA
<213>  Homo sapiens

<400>  302
gcatatatct gacttaccta taaatggcgt atcacgaggc cctttcgtct tcacctcgag     60

aaatcataaa aaatttattt gctttgtgag cggataacaa ttataataga ttcaattgtg    120

agcggataac aatttcacac agaattcatt aaagaggaga aattaactat gagaggatcg    180

catcaccatc accatcacgg tcgacccacg cgtccgcggc cggactacga gattgagatt    240

tcggatgctt cagaggtaga aaaggaaatt aataaagccc agaatgccat cgccggggaa    300

ggaatgggaa tcagtcatga gctaatcacc ctggagatca gctcccgaga tgtcccggat    360

ctgactctaa tagaccttcc tggcataacc agagtggctg tgggcaatca gcctgctgac    420

attgggtata agatcaagac actcatcaag aagtacatcc agaggcagga gacaatcagc    480

ctggtggtgg tccccagtaa tgtggacatc gccaccacag aggctctcag catggcccag    540

gaggtggacc ccgagggaga caggaccatc ggaatcttga cgaagcctga tctggtggac    600

aaaggaactg aagacaaggt tgtggacgtg gtgcggaacc tcgtgttcca cctgaagaag    660

ggttacatga ttgtcaagtg ccggggccag caggagatcc aggaccagct gagcctgtcc    720

gaagccctgc agagagagaa gatcttcttt gagaaccacc catatttcaa ggatctgctg    780

gaggaaggaa aggccaccgt tccctgcctg gcacaaaact ttaccaccga acccggccgc    840

gaatccgcaa tgcaagctcc attaactgaa cctcgaaccc cgttgataca tcccgcaatg    900

gacccccgaa ctccctcagg attttgttca gaacccaccg cataacacaa cgctccttct    960

tctcactaaa actcccccac cacactccac actcagaccc cccagacctc acacaaccac   1020

aaatggccca accaccccac cctgacaacc cacactgcag cccactctaa ccagacaccc   1080

ccctgacgca ccccaccacc ccccactcac accttacacc tacctctata acacaccgac   1140

gcacctcagc taattcaact tcaccgctat tcacctctgc acacacacat cagactccca   1200

acaagaacac tacctcagcc caaccacctg tctcaagccc taaaatccca ctgacagtct   1260

acgacctatc gcgcactaca gtggatccca tcatctctac tctactccat cacgcctaca   1320

tacccagctt tcacaccttc atcaaacaca ccacacctag atactcaacc ctatcagcat   1380

cacg                                                                1384


<210>  303
<211>  777
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (682)..(682)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (751)..(751)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (755)..(777)
<223>  n is a, c, g, or t

<400>  303
atagagagat actatgagag gtcgcatcac catcaccatc acggatccta tttaggtgac     60

actatagaat cgtcgactct ggaccttggc tgtcactcag ttgggacgga ggtagaggcc    120

agggcagcgc gtccgggagc ggagtccgcg cccgccgccg ccatgccgga cagctgggac    180

aaggatgtgt accctgagcc cccgcgccgc acgccggtgc agcccaatcc catcgtctac    240

atgatgaaag cgttcgaccc catcgtggac cgacccgtga ccctcgtgag agaatttata    300

gagcggcagc acgcaaagaa caggtattac tactaccacc ggcagtaccg ccgcgtgcca    360

gacatcactg agtgcaagga ggaggacatc atgtgcatgt atgaagccga aatgcagtgg    420

aagagggact acaaagtcga ccaagaaatt atcaacatta tgcaagatcg gctcaaagcc    480

tgtcagcaga gggaaggaca gaactaccag cagaactgta tcaaggaagt ggagcagttc    540

acccaggtgg ccaaggccta ccaggaccgc tatcaggacc tgggggccta cagttctgcc    600

aggaagtgcc tggccaaaca gaggcagagg atgctgcaag agagaaaagc tgcaaaagag    660

gccgccgctg ccacctcctg angcagctgt gggtgcccct gctgtgtggc tctgtatgac    720

tgttgctgaa atataaagcc cctgcacctg ncaannnnnn nnnnnnnnnn nnnnnnn       777


<210>  304
<211>  1100
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (16)..(16)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (740)..(740)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (776)..(776)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (804)..(804)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (816)..(816)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (840)..(840)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (844)..(844)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (866)..(866)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (891)..(891)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (894)..(894)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (906)..(906)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (916)..(916)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (930)..(930)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (935)..(935)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (938)..(938)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (961)..(961)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (973)..(973)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (975)..(975)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (986)..(986)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (996)..(996)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1008)..(1008)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1013)..(1013)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1024)..(1024)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1032)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1034)..(1034)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1036)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1038)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1047)..(1047)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1054)..(1054)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1075)..(1075)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1078)..(1079)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1082)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1091)..(1091)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1099)..(1099)
<223>  n is a, c, g, or t

<400>  304
naattagaga aattanctat gagaggatcg catcaccatc accatcacgg atcctattta     60

ggtgacacta tagaatcgtc gacccacgcg tccgtgcaga gcaatgacga ggtgttggct    120

gaggtgactt cgtgggacct gcccccgttg actgaccgct accgcagggc ctgccagagc    180

ctggggcaag gggagcacca acaggtgctg caggccgtgg agctccaggg cttgggcctc    240

tcgttcagcg cctgctccct ggccctggac caggcccagc ttacacccct gctgcgggcc    300

ctcaagctgc acacagcact ccgggagctg cgcctggcag ggaaccggct gggggacaag    360

tgtgtggctg agctggtggc tgccctgggc accatgccca gcctggccct ccttgacctc    420

tcctccaatc acctgggtcc cgaaggcctg cgccagcttg ccatggggct cccaggccaa    480

gccaccttgc agagtttgga ggagctggac ttaagcatga accccctggg ggacggctgt    540

ggccagtccc tggcctccct cctgcacgcc tgccccttac tcagcaccct gcgcctgcag    600

gcgtgtggct tcggccccag cttctttctg agccaccaga cagcactggg tagtgctttc    660

caagatgctg agcacctgaa gaccctgtcc ctgtcctaca acgccctggg agcccctgcc    720

ctggccagga ccctgcagan cctgcccgcc ggcaccctcc tgcacttaaa gctcanctcc    780

gtggcagccg gcaagggtga ttcngacctc atggancctg tattccgata cctggccaan    840

gaangctgtg ctctaaccca cctgancctg tctgcaaacc acctggggga naangctgtt    900

aaaaanctgt gcaaangtct ctctctgtgn ccctncantc atctcactgg atttgtctgc    960

naaccctgaa atnanctgtg cnactngnaa aactcntgtc caccntcnaa aancggcccc   1020

aagncttaac tncntngnct gtcaggntgc cccntcaang gtccctgggn ctggnctnng   1080

gnaaaaaaaa ncccccaant                                               1100


<210>  305
<211>  1215
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (815)..(815)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (905)..(905)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (945)..(945)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (957)..(957)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (970)..(970)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1002)..(1002)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1013)..(1013)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1017)..(1017)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1026)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1028)..(1028)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1042)..(1042)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1048)..(1048)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1067)..(1067)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1087)..(1087)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1095)..(1095)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1100)..(1100)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1102)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1116)..(1116)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1120)..(1120)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1124)..(1124)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1126)..(1126)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1138)..(1138)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1151)..(1151)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1154)..(1154)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1157)..(1157)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1170)..(1170)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1172)..(1172)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1175)..(1175)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1180)..(1180)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1194)..(1194)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1205)..(1205)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1211)..(1213)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1215)..(1215)
<223>  n is a, c, g, or t

<400>  305
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg cggcggtggc ggcggagacc cgaacatggc    120

gaccgcgcgc accttcgggc ccgagcggga agccgagccg gccaaggaag cgcgcgtcgt    180

gggctcggag cttgtggaca cttatacggt ttacatcatc caggtcactg atggcagcca    240

tgagtggaca gtaaagcacc gctacagcga cttccatgac ctgcatgaaa agctcgttgc    300

agagagaaag attgataaaa acctgcttcc gcccaaaaag ataattggga aaaactcaag    360

aagcttggtg gagaagaggg agaaggatct ggaggtctac ctccagaagc tcctggctgc    420

cttccctggc gtgaccccca gagtactggc ccacttcttg cattttcact tctatgagat    480

aaatggcatc accgcggcac tggctgaaga gctctttgag aaaggagaac agctcctggg    540

ggccggcgag gtctttgcca ttggacccct gcagctgtat gccgtcacgg agcagctgca    600

gcagggaaag cccacgtgcg ccagtgggga tgccaagacc gacctcgggc acatcctgga    660

cttcacctgt cgccttaagt accttaaggt ttctggcaca gaaggacctt ttgggaccag    720

caacattcag gagcagctcc tgccgttcga cctatcaata ttcaagtccc tgcatcaggt    780

ggagataagt cactgtgatg ctaagcacat caganggctg gtcgcatcga agcccacctt    840

agccacgctg agtgtccgct tctcagcaac ctcgatgaag gaagtccttg ttcctgaagc    900

ctcanaattt gatgagtggg agcctgaagg cacaacccta gaagncctgt gactgcngtc    960

atccccactn ggcaggcatt gaccccgctt gaacctggac cncaanagca ttntccnaaa   1020

tcgacnantc tgtgaaatga tncccaanat tgatttctgg acctgantcn aatggattgc   1080

tggttgngga aatcngcacn cntgtnaact tgggcnttgn actntnctaa aaaagctncc   1140

tcttggaagg nttnccncca gttggggaan tncanacttn acctgggggc accnctaaag   1200

ttganggccg nnnan                                                    1215


<210>  306
<211>  888
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (648)..(648)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (650)..(650)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (672)..(672)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (695)..(695)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (733)..(733)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (737)..(737)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (740)..(740)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (747)..(747)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (754)..(754)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (760)..(760)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (765)..(765)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (769)..(769)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (805)..(805)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (807)..(807)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (828)..(828)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (831)..(831)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (842)..(843)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (846)..(846)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (858)..(858)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (876)..(876)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (881)..(881)
<223>  n is a, c, g, or t

<400>  306
cnatgagagg atcgcatcac catcaccatc acggatccta tttaggtgac actatagaat     60

cgtcgaccca cgcgtccgct ccttcactct accctaagaa cacagatcta tttgagatga    120

ttgagaagat gcagggaagc aggatggatg aacaacgctg ctccttcccg ccgcccctca    180

aaacagagga ggactacatt ccatacccga gcgtgcacga ggtcttgggg cgagaaggac    240

ccttccccct catcctgctg ccccagtttg ggggctactg gattgagggc accaaccacg    300

aaatcaccag catccccgag acagagccac tgcagtcgcc cacaaccaag gtgaagctcg    360

agtgcaaccc cacagcccgc atctaccgga agcactttct cggcaaggag catttcaatt    420

actactcact ggacactgcc ctcggccacc ttgtcttctc actcaagtac gatgtcatcg    480

gggaccaaga gcacctgcgg ctgctgctca ggaccaagtg ccggacatac catgatgtca    540

tccccatctc ctgcctcacc gagttcccta atgttgtcca gatggcaaag ttggtgtgtg    600

aagacgtcaa tgtggatcgg ttctatccct gtgctctacc cccaaggntn ccgggctcat    660

cgttcacctt tngacgagca tgtcatcaag caatnaactt ccaagtttgg gggtcctttt    720

atcagaaagc ttngggnaan acctccngag gaanaaactn ctttncgcnc ccaatggggg    780

aaaagtcccc cccttttcgg ggggngntcc cttggaaatt tccttggncc nagaaagggt    840

cnnaanttgg cagggacntt ttaaaggggg tttccngaag ngaaggcc                 888


<210>  307
<211>  752
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (584)..(584)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (608)..(608)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (622)..(622)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (639)..(639)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (649)..(649)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (677)..(677)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (680)..(680)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (703)..(704)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (708)..(708)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (710)..(710)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (718)..(718)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (720)..(720)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (723)..(723)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (730)..(730)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (739)..(741)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (745)..(750)
<223>  n is a, c, g, or t

<400>  307
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg cctcgagttt ggaagaaaac aaggcagtag    120

taaggaggaa caggaaagga agaggctgat ccacaaacac aagcgtgaat ttaaaggggc    180

cgttcgagaa atccgcaagg acaatcagtt cctggcgagg atgcaactct cagaaatcat    240

ggaacgggat gcggaaagaa agcggaaagt aaagcagctt tttaacagcc tggctacaca    300

ggaaggcgaa tggaaggctc tgaagaggaa aaagttcaaa aaataaatta cattttataa    360

ataaggcaag gaactggaca ttacctcaca tctgcaattc caaccctctg ggaggccaag    420

gcaggaggat tgcttcagcc cgggagttcg agaccagcct gggcaacaca ggaagacccc    480

gtctctacca gaaaaacata aaaattagcc aagtgtggtg gcacgcacct gtggtcccaa    540

ctactcggga ggctgaagca ggaggactgc ttgagctgag tccnaggtta cagtgagccg    600

tgattgancc actgcactcc ancctcggcc acagtgcang actgtgtcnc ttaaaaaaaa    660

attttttttt ttttganacn gaatttttgc tcttgttgcc cannctgnan tgcactgncn    720

canccttccn cctccctgnn nttcnnnnnn at                                  752


<210>  308
<211>  872
<212>  DNA
<213>  Homo sapiens

<400>  308
aagagattac tatgagaggt cgcatcacca tcaccatcac ggatcctatt taggtgacac     60

tatagaatcg tcgactctgg accttggctg tcactcagtt ggaagtgtta agagacccaa    120

agcccggaga gtgggctccc aggacagctt gctggagatc accttccgct ccggagccct    180

gcccgtgctc tgtgacccca cgacccctaa gccagaggac ctgcattcgc cgccgctggg    240

cgcgggcttg gctgactttg cccaccctgc gggcagcccc ttaggtaggc gcgactgctt    300

ggtgaagctg gagtgctttc gctttcttcc gcccgaggac accccgcccc cagcgcaggg    360

cgaggcgctc ctgggcggtc tggagctcat caagttccga gagtcaggca tcgcctcgga    420

gtacgagtcc aacacggacg agagcgagga gcgcgactcg tggtcccagg aggagctgcc    480

gcgcctgctg aatgtcctgc agaggcagga actgggcgac ggcctggatg atgagatcgc    540

cgtgtaggtg ccgagggcga ggagatggag gcggcggcgt ggctggaggg gccgtgtctg    600

gctgctgccc gggtagggga tgcccagtga atgtgcactg ccgaggagaa tgccagccag    660

ggcccgggag agtgtgaggt tttcaggaag tattgagatt ctgctttgga gggtaaagtg    720

gggaaagaaa tcgattccca gaggtgaatc agctcctctc ctacttgtga ctagagggtg    780

gtggaggtaa ggccttccag agcccatggc ttcaagagag ggtctctctc caggactgcc    840

aggctgctgg aagactgccc ctactgctgc at                                  872


<210>  309
<211>  1213
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (925)..(925)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (935)..(935)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (939)..(939)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (941)..(941)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (948)..(948)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (986)..(986)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (989)..(989)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (991)..(991)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1014)..(1014)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1021)..(1021)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1031)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1049)..(1049)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1053)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1056)..(1056)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1069)..(1069)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1082)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1090)..(1090)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1100)..(1100)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1108)..(1108)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1115)..(1115)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1129)..(1129)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1138)..(1138)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1146)..(1146)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1153)..(1153)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1162)..(1162)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1172)..(1172)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1175)..(1175)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1177)..(1177)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1182)..(1182)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1185)..(1185)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1196)..(1196)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1204)..(1204)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1207)..(1207)
<223>  n is a, c, g, or t

<400>  309
atngagaaat tactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg agcgcagctg tgagggagtc gctgtgatcc    120

ggggccccgg aacccgagct ggagctgaag cgcaggctgc ggggcgcgga gtcgggagtg    180

caggcctgag tgttccttcc agcatgtcgg agggggagtc ccagacagta cttagcagtg    240

gctcagaccc aaaggtagaa tcctcatctt cagctcctgg cctgacatca gtgtcacctc    300

ctgtgacctc cacaacctca gctgcttccc cagaggaaga agaagaaagt gaagatgagt    360

ctgagatttt ggaagagtcg ccctgtgggc gctggcagaa gaggcgagaa gaggtgaatc    420

aacggaatgt accaggtatt gacagtgcat acctggccat ggatacagag gaaggtgtag    480

aggttgtgtg gaatgaggta cagttctctg aacgcaagaa ctacaagctg caggaggaaa    540

aggttcgtgc tgtgtttgat aatctgattc aattggagca tcttaacatt gttaagtttc    600

acaaatattg ggctgacatt aaagagaaca aggccagggt catttttatc acagaataca    660

tgtcatctgg gagtctgaag caatttctga agaagaccaa aaagaaccac aagacgatga    720

atgaaaaggc atggaagcgt tggtgcacac aaatcctctc tgccctaagc tacctgcact    780

cctgtgaccc ccccatcatc catgggaacc tgacctgtga caccatcttc atccagcaca    840

acggactcat caagattggc tctgtggctc ctgacactat caacaatcat gtgaagactt    900

gtcgagaaga gcaaaaaaat ctacncttct ttgcnccana ntatgganaa gtcactaatg    960

tgacaacagc agtggacatc tactcnttng ncatgtgtgc nctggaaatg gcantgcttg   1020

naaattcagg ncaatggaaa gtcctcatnt gtnccnaagg aagccctcng cagtgccctc   1080

cngcttctan aaaacccttn cagagggntt ttttncaaag tgcctgcant ttgacctntt   1140

ccaaancaaa acnaaaaaat tntgttcccc cnacntnttg anggncctcc ttaaantctt   1200

gggnccntgg ttg                                                      1213


<210>  310
<211>  1147
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (912)..(912)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (922)..(922)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (926)..(926)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (952)..(952)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (958)..(958)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (960)..(960)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (994)..(994)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1004)..(1004)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1058)..(1058)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1061)..(1061)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1076)..(1076)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1079)..(1079)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1084)..(1085)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1087)..(1087)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1097)..(1097)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1102)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1107)..(1107)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1122)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1127)..(1127)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1130)..(1130)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1139)..(1139)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1146)..(1146)
<223>  n is a, c, g, or t

<400>  310
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccga tgagatcgac cttcagaaga tgcccttggg    120

gaagctgagc aaaaggcaga tccaggccgc atactccatc ctcagtgagg tccagcaggc    180

ggtgtctcag ggcagcagcg actctcagat cctggatctc tcaaatcgct tttacaccct    240

gatcccccac gactttggga tgaagaagcc tccgctcctg aacaatgcag acagtgtgca    300

ggccaaggtg gaaatgcttg acaacctgct ggacatcgag gtggcctaca gtctgctcag    360

gggagggtct gatgatagca gcaaggatcc catcgatgtc aactatgaga agctcaaaac    420

tgacattaag gtggttgaca gagattctga agaagccgag atcatcagga agtatgttaa    480

gaacactcat gcaaccacac acaatgcgta tgacttggaa gtcatcgata tctttaagat    540

agagcgtgaa ggcgaatgcc agcgttacaa gccctttaag cagcttcata accgaagatt    600

gctgtggcac gggtccagga ccaccaactt tgctgggatc ctgtcccagg gtcttcggat    660

agccccgcct gaagcgcccg tgacaggcta catgtttggt aaagggatct atttcgctga    720

catggtctcc aagagtgcca actactgcca tacgtctcag ggagacccaa taggcttaat    780

cctgttggga gaagttgccc ttggaaacat gtatgaactg aagcacgctt cacatatcag    840

caagttaccc aagggcaagc acagtgtcaa aggtttgggc aaaactaccc ctgatccttc    900

agctaacatt antctggatg gngtanacgt tcctcttggg gaccgggatt cntctggngn    960

gaatgacccc tctctactat ttancgagta catngtctat gaanttgctc aggtaaatct   1020

gaagtatctg ctgaaactga aattcatttt taaaaccncc ngggggtatt gggganagnt   1080

agcnnantcc ccccggnggc tntggtngaa tttccccgaa nngtttntgn accaattcnc   1140

tgggcnc                                                             1147


<210>  311
<211>  871
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (680)..(680)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (750)..(751)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (756)..(756)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (766)..(766)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (826)..(826)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (843)..(843)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (851)..(851)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (868)..(868)
<223>  n is a, c, g, or t

<400>  311
taaggaatta ctatgagagg tcgcatcacc atcaccatca cggatcctat ttaggtgaca     60

ctatagaatc gtcgactctg gaccttggct gtcactcagt taaggaagtc aagaaggcct    120

atgtggaggc caaccagatg ctgggcgatc tcatcaaggt gacgccctcc tccaagatcg    180

tgggggacct ggcccagttt atggtgcaga atggattgag ccgggcagag gccgaagctc    240

aggcggaaga gctgtccttt ccccgctccg tggtggagtt cctgcagggc tacatcggtg    300

tcccccatgg ggggttcccc gaaccctttc gctctaaggt actgaaggac ctgccaaggg    360

tggaggggcg gcctggagcc tccctccctc ccctggatct gcaggcactg gagaaggagc    420

tggtagaccg gcatggggag gaggtgacgc cggaagatgt gctctcagca gctatgtacc    480

ccgatgtgtt tgcccacttc aaggacttca ctgccacctt tggccccctg gatagcctga    540

atactcgcct cttcctgcag ggacccaaga tcgcagagga gtttgaggtg gagctggagc    600

ggggcaagac gctgcacatc aaagccctgg ccgtgagcga cctgaaccgg gccggccaga    660

ggcaggtctt ctttgagctn catgggcagc tgcggtccat cttggtcagg acaccaggcc    720

atgaaggaga tgcacttcca ccccaggccn ntaagnacgt gagggncaga tcgggcgcca    780

tgcctgggaa gtgataaatc aagtggtgca ggggcaggtg ccaggncagc ccctggtgtg    840

tcntgcatga natgaaaatg gtgactcncc t                                   871


<210>  312
<211>  1096
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (809)..(809)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (882)..(882)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (901)..(901)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (924)..(924)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (929)..(929)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (951)..(951)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (958)..(958)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (961)..(961)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (973)..(973)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (983)..(983)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (985)..(985)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (995)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1019)..(1019)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1031)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1034)..(1034)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1039)..(1039)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1041)..(1041)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1045)..(1045)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1049)..(1049)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1054)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1060)..(1060)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1067)..(1067)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1085)..(1085)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1092)..(1092)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1095)..(1095)
<223>  n is a, c, g, or t

<400>  312
tantagagag attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cgctgaactc cagctggatg agggctggat    120

ggatgatgac aggaacgact ttctggatga cctgcacatg gacatgctgg aggagcagca    180

ccaccaggcc atgcaattca cagctagcgt gctgcagcag aagaagcacg acgaagacgg    240

tgggaccaca gatacagcca ccatcttgtc caaccagcac gagaaggaca gcggtgtggg    300

gcggaccgac gagagcaccc gtaatgacga gagctcggag caagagaaca atggcgacga    360

cgccaccgca tcctccaacc cgctggcggg gcagaggaag ctcacctgca gccaggacac    420

cttgggcagc ggcgacctgc ccttcagcaa cgagtctttc atttcggccg actgcacgga    480

cgccgactac ctggggatcc cggtggacga gtgcgagcgc ttccgcgagc tcctggagct    540

caagtgccag gtgaagagcg ccacccctta cggcctgtac taccctagcg gccccctgga    600

cgccggcaag agtgaccctg agagcgtgga caaggagctg gagctgctga acgaagagct    660

gcgcagcatc gagctggagt gcctgagcat cgtgcgcgcc cacaagatgc agcagctcaa    720

ggagcagtac cgcgagtcct ggatgctgca caacagcggc ttccgcaact acaacaccag    780

catcgacgtg cgcagacacg agctctcana tatcaccgag ctcccggaga aatccgacaa    840

ggacagctcg agcgcctaca acacaggcga gagctgccgc ancaccccgc tcaccctgga    900

natctccccc gacaactcct tgangaaanc ggcggaaggc atcactgccc naacancnaa    960

ngggctgtgg ggnaccacgg aancntacgg gccancntcc aaaaatctgc tctccatcnc   1020

ggaaaatccc naantgggnc ncccntacnt atnncccgtn cctgaangan cttggacccc   1080

accancccct gnaanc                                                   1096


<210>  313
<211>  1094
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (788)..(788)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (862)..(862)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (870)..(870)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (882)..(882)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (907)..(907)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (920)..(920)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (922)..(922)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (931)..(931)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (992)..(992)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (995)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1009)..(1009)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1017)..(1017)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1030)..(1030)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1033)..(1033)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1043)..(1043)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1049)..(1049)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1054)..(1054)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1060)..(1060)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1062)..(1062)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1064)..(1064)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1074)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1080)..(1081)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1084)..(1085)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1087)..(1087)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1092)..(1092)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1094)
<223>  n is a, c, g, or t

<400>  313
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc ggacgcgtgg gcggacgcgt gggtcaagtc    120

ggcctgcaag gaagacatcc ccagcgaaaa gagtgaggag atcactactg gcagtgcctg    180

gtttagcttc ctggagagcc acaacaagct ggacaaagac aacctctcct acattgagca    240

catctttgag atctcccgcc gtcctgacct actcactatg gtggttgact acagaacccg    300

tgtgctgaag atctctgagg aggatgagct ggacaccaag ctaacccgta tccccagtgc    360

caagaagtac aaagacatta tccggcagcc ctctgaggaa gagatcatca aattggctcc    420

cccaccgaag aaggcctgag caagggggag gaagaggagg aaggttggac cttcatcaga    480

ccactccctt cccccatcct ccaggagagg gggcaagggc aacccaccat ctacccactt    540

actaacctgg tcctaacccc cttactgtgc gcgtgtgtgt gcgtgtgcgc acgctctggc    600

tgtttgtcta tatgtctagc tcatctagtt cctcttctta aggggatggg ggtcaggggc    660

taggggaggg ggctgagttt ccccacttta ggaggaggtg ggggctattt ctatgcaaat    720

agaaatcagc acattcctcc tacttccctt tcctccactc cccccatatc tttaaagtgt    780

ggaagcanaa aggacctgca ttttcctaca ttgaggagct gacatagggg taaggtatgg    840

gagaggtagg tggatccagg gnaaaagcan tggggacgga angctttttc aaaaaacatt    900

aaattcncat gcagtctcan anactattta nacaaagttc agttaggagc ttttangatg    960

ggggagtaaa ctttaatggg aagggaaggc tnggntgctg gaaaaaagna aaaaccnaan   1020

tgggttaaan agnantctta aantcctanc ccancctaan gngncctgcc cctntggccn   1080

ntgnngnaaa ancn                                                     1094


<210>  314
<211>  873
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (781)..(782)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (792)..(792)
<223>  n is a, c, g, or t

<400>  314
nnggaaggat atggaagtga cgtgagagga tgcatcccat caccatcacg gatcctattt     60

aggtgacact atagaatcgt cgactctgga ccttggctgt cactcagtta gggacatgac    120

ctctgtgctg aagcaggatc gggagcggct ccgagccatg cagaagcagc agcctcggtt    180

ttctgaggac cagcggcggg aactgggtgc tgtgcactcc tgggtccgga agggccaact    240

gcctcgggct cttgatgtga tggcctgtgt ggactgtggg agcagcaccc aagatcctgg    300

tcaccctgat gacccactct tctcagagct ggatggactg gggctggagc ccatggaaga    360

gggtggaggc gagcagggca gcagcggtgg cggcagtggt gagggagagg gctgcgagga    420

ggcccaaggc ggggccaagg cttcaagctc tcaggacttg gctatggagg aggaggaaga    480

aggcaggagc tcatccagtc cagccttacc tacagcagga aactgcacca gctagactcc    540

attctgggac catctccagg agtccatgag aggctttctt ctcctatgtc ccaattctca    600

gaactcagat gtggctagac caaccagtgg gaaactgccc cagcttctcc caccataggg    660

ggccggaccc ccatcaccag cctaggatcc aggggctgcc tctggcctct tagggagcag    720

agagcagaac tccgcagccc agcccagagg agtgtcacct cccacctttg gagagaatcc    780

nntcctccct gnacaaagtg ctgacagctg ctgaagtgcc tctcatattc agctgagctg    840

atctgactct gagggtgggc tgcactattt tat                                 873


<210>  315
<211>  1114
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (829)..(829)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (932)..(932)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (936)..(936)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (940)..(940)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1010)..(1010)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1016)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1022)..(1023)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1031)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1033)..(1033)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1036)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1042)..(1042)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1044)..(1044)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1050)..(1050)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1064)..(1064)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1078)..(1078)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1100)..(1100)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1114)..(1114)
<223>  n is a, c, g, or t

<400>  315
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg gaaacatgcc tgcatattct acgatgagaa    120

taccaaacat tatgagctgt taaactacag tgagcatggg acaacggtgg acaatgtgct    180

gtattcatgt gacttctcgg agaagacccc gccaaccccc ccaagcagta ttgttgccaa    240

agtgcagagt gtcatcaggc gccgccggca ccagaaacag gacgaagagc caagtgagga    300

ggcagccatg atgagttccc aggcccaggg gccgcagcgg agaccctgca attgcaaagc    360

cagcagctcg agcttgattg ggggcagtgg ggccggctgg gagggcacag ccttactgca    420

ccatggcagc tacatcaagc tgggctgcct gcagtttgtc ttcagcatca ctgagtttgc    480

gaccaaacag cccaaaggcg atgccagcct gctgcaggat ggggtcttgg ccgagaagct    540

ctctctcaag ccccaccagg gccctgtgct gcgctccaac tctgttcctt aggactggcg    600

gctaccccgc cactggcctg tacacccacc caagactcct gcaatgcaaa aatgtacaca    660

aaccaagccc gggtgttttc tatactctac cagaaaccct tcaactacaa tctttgcatg    720

aaatgaagaa aaccttttga ctgtttttta aaaatccttt ttcttttctc aagttctagg    780

gggcatttgc acatatattt gtactcaaca tttcatggga aagcggcana cctgagctga    840

agaacagcgt gggcagggag ggaaaagacc cagggtctgg acacttcctc caacacaaaa    900

cctttcccaa ccaacttcct ggtccctccc cntcgnccan attgtaaata atcaaaaact    960

tgttctattt ttggggcatg acantanttt tatattaaaa aaaaaataan gttttncata   1020

cnncaaaatc nanacnaaan cntngttttn ttaaaaaaaa atcnctaccc ncccttcntt   1080

ccagggttcc cccccncccn tttnttttcc tttn                               1114


<210>  316
<211>  548
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (5)..(5)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (36)..(36)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (38)..(38)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (46)..(46)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (68)..(68)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (431)..(431)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (452)..(452)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (457)..(457)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (470)..(470)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (475)..(475)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (483)..(483)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (504)..(504)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (507)..(507)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (521)..(521)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (524)..(526)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (530)..(531)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (540)..(543)
<223>  n is a, c, g, or t

<400>  316
gaatntaaaa attatttgct ttgtgagcgg atacantnta tgattnattg tgagcggata     60

acaatttnca cagaattatt aaagaggaga aattaactat gagaggatcg catcaccatc    120

accatcacgg atcctattta ggtgacacta tagaatcgtc gacccacgcg tccggccgaa    180

ccgcagcttc ttggcttagg tacttctact cacagcggcc gattccgagg ccaactccag    240

caatggcttt tgcaaatctg cggaaagtgc tcatcagtga cagcctggac ccttgctgcc    300

ggaagatctt gcaagatgga gggctgcagg tggtggaaaa gcagaacctt agcaaagagg    360

agctgatagc ggagctgcag gactgtgaag gccttattgt tcgctctgcc accaaggtga    420

ccgctgatgt natcaacgca gctgagaaac tncaggnggt ggggcagggn ctggnacagg    480

tgnggacaat gtggatctgg aggncgnaac aaaggaaggg natnnntggn natgaacacn    540

nnnaatgg                                                             548


<210>  317
<211>  1251
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (858)..(858)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (892)..(892)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (899)..(899)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (901)..(901)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (941)..(941)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (945)..(945)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (972)..(972)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (976)..(976)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (986)..(986)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1030)..(1030)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1038)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1041)..(1042)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1045)..(1045)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1066)..(1066)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1073)..(1073)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1079)..(1079)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1081)..(1081)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1092)..(1092)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1100)..(1100)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1122)..(1122)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1126)..(1126)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1147)..(1147)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1152)..(1152)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1158)..(1158)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1193)..(1193)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1195)..(1195)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1200)..(1200)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1205)..(1205)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1212)..(1212)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1214)..(1214)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1216)..(1216)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1224)..(1224)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1240)..(1240)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1242)..(1242)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1244)..(1245)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1251)..(1251)
<223>  n is a, c, g, or t

<400>  317
aaagagaaat tactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg cgcagagccg cgtcgccaag ccgcatcagc    120

gcgagaagat cctaaatgag attgagctgc accgagacct gcagcaccgc cacatcgtgc    180

gtttttcgca ccactttgag gacgctgaca acatctacat tttcttggag ctctgcagcc    240

gaaagtccct ggcccacatc tggaaggccc ggcacaccct gttggagcca gaagtgcgct    300

actacctgcg gcagatcctt tctggcctca agtacttgca ccagcgcggc atcttgcacc    360

gggacctcaa gttgggaaat tttttcatca ctgagaacat ggaactgaag gtgggggatt    420

ttgggctggc agcccggttg gagcctccgg agcagaggaa gaagaccatc tgtggcaccc    480

ccaactatgt ggctccagaa gtgctgctga gacagggcca cggccctgag gcggatgtat    540

ggtcactggg ctgtgtcatg tacacgctgc tctgcgggag ccctcccttt gagacggctg    600

acctgaagga gacgtaccgc tgcatcaagc aggttcacta cacgctgcct gccagcctct    660

cactgcctgc ccggcagctc ctggccgcca tccttcgggc ctcaccccga gaccgcccct    720

ctattgacca gatcctgcgc catgacttct ttaccaaggg ctacaccccc gatcgactcc    780

ctatcagcag ctgcgtgaca gtcccagacc tgacaccccc caacccagct aggagtctgt    840

ttgccaaagt taccaaancc ctctttggca gaaagaagaa aattaagaat cntgcccang    900

naaaggatga agtctccggt tttggtgagc ggcctcatgc nccanatccg tttggccatc    960

aggatgccag gnccanaagg ctccancaac ttttggncca ncccntgtca gcctngttaa   1020

aaaaacaccn tgaaaaanag nntcnccccc gtgggaaact ggcaancaan ggnaaatgna   1080

ntttaaaaaa gntttnantn tggccccaaa aaatggaatc cncccntttg tgtctcgaaa   1140

aattttnaaa cncttttncc cccacggaaa aaaaacccgg ccccctgggc cancnaaaan   1200

ccttnggggg gntnanaaag gggnttaaaa cccaaaaaan tncnntttgg n            1251


<210>  318
<211>  2697
<212>  DNA
<213>  Homo sapiens

<400>  318
atggcactgc agctctgggc cctgaccctg ctgggcctgc tgggcgcagg tgccagcctg     60

aggccccgca agctggactt cttccgcagc gagaaagagc tgaaccacct ggctgtggat    120

gaggcctcag gcgtggtgta cctgggggcg gtgaatgccc tctaccagct ggatgcgaag    180

ctgcagctgg agcagcaggt ggccacgggc ccggccctgg acaacaagaa gtgcacgccg    240

cccatcgagg ccagccagtg ccatgaggct gagatgactg acaatgtcaa ccagctgctg    300

ctgctcgacc ctcccaggaa gcgcctggtg gagtgcggca gcctcttcaa gggcatctgc    360

gctctgcgcg ccctgagcaa catctccctc cgcctgttct acgaggacgg cagcggggag    420

aagtctttcg tggccagcaa tgatgagggc gtggccacag tggggctggt gagctccacg    480

ggtcctggtg gtgaccgcgt gctgtttgtg ggcaaaggca atgggccaca cgacaacggc    540

atcatcgtga gcactcggct gttggaccgg actgacagca gggaggcctt tgaagcctac    600

acggaccacg ccacctacaa ggccggctac ctgtccacca acacacagca gttcgtggcg    660

gccttcgagg acggccccta cgtcttcttt gtcttcaacc agcaggacaa gcacccggcc    720

cggaaccgca cgctgctggc acgcatgtgc agagaagacc ccaactacta ctcctacctg    780

gagatggacc tgcagtgccg ggaccccgac atccacgccg ctgcctttgg cacctgcctg    840

gccgcctccg tggctgcgcc tggctctggc agggtgctat atgctgtctt cagcagagac    900

agccggagca gtggggggcc cggtgcgggc ctctgcctgt tcccgctgga caaggtgcac    960

gccaagatgg aggccaaccg caacgcctgt tacacaggca cccgggaggc ccgtgacatc   1020

ttctacaagc ccttccacgg cgatatccag tgcggcggcc acgcgccggg ctccagcaag   1080

agcttcccat gtggctcgga gcacctgccc tacccgctgg gcagccgcga cgggctcaga   1140

ggcacagccg tgctgcagcg tggaggcctg aacctcacgg ccgtgacggt cgccgccgag   1200

aacaaccaca ctgttgcttt tctgggcacc tctgatggcc ggatcctcaa ggtgtacctc   1260

accccagatg gcacctcctc agagtacgac tctatccttg tggagataaa caagagagtc   1320

aagcgcgacc tggtactgtc tggagacctg ggcagcctgt acgccatgac ccaggacaag   1380

gtgttccggc tgccggtgca ggagtgcctg agctacccga cctgcaccca gtgccgcgac   1440

tcccaggacc cctactgcgg ctggtgcgtc gtcgagggac gatgcacccg gaaggccgag   1500

tgtccgcggg ccgaggaggc cagccactgg ctgtggagcc gaagcaagtc ctgcgtggcc   1560

gtcaccagcg cccagccaca gaacatgagc cggcgggccc agggggaggt gcagctgacc   1620

gtcagccccc tccctgccct gagcgaggag gacgagttgc tgtgcctttt tggggagtcg   1680

ccgccacacc ccgcccgcgt ggagggcgag gccgtcatct gcaactcccc aagcagcatc   1740

cccgtcacac cgccaggcca ggaccacgtg gccgtgacca tccagctcct ccttagacga   1800

ggcaacatct tcctcacgtc ctaccagtac cccttctacg actgccgcca ggccatgagc   1860

ctggaggaga acctgccgtg catctcctgc gtgagcaacc gctggacctg ccagtgggac   1920

ctgcgctacc acgagtgccg ggaggcttcg cccaaccctg aggacggcat cgtccgtgcc   1980

cacatggagg acagctgtcc ccagttcctg ggacccagcc ccctggtgat ccccatgaac   2040

cacgagacag atgtgaactt ccagggcaag aacctggaca ccgtgaaggg ttcctccctg   2100

cacgtgggca gtgacttgct caagttcatg gagccggtga ccatgcagga atctgggacc   2160

ttcgcctttc ggaccccaaa gctgtcccac gatgccaacg agacgctgcc cctgcacctc   2220

tacgtcaagt cttacggcaa gaatatcgac agcaagctcc atgtgaccct ctacaactgc   2280

tcctttggcc gcagcgactg cagcctgtgc cgggccgcta accccgacta caggtgtgcg   2340

tggtgcgggg gccagagcag gtgcgtgtat gaggccctgt gcaacaccac ctccgagtgc   2400

ccgccgcccg tcatcaccag gatccagcct gagacgggcc ccctgggtgg gggcatccgc   2460

atcaccatcc tggggtccaa tttgggcgtc caagcagggg acatccagag gatctctgtg   2520

gccggccgga actgctcctt tcagccggaa cgttactccg tgtccacccg gatcgtgtgt   2580

gtgatcgagg ctgcggagac gcctttcacg gggggtgtcg aggtggacgt cttcgggaaa   2640

ctgggccgtt cgcctcccaa tgtccagttc accttccaac agcccaagcc tctcagt      2697


<210>  319
<211>  847
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (816)..(816)
<223>  n is a, c, g, or t

<400>  319
agaaatacta tgagaggtcg catcccatca ccatcacgga tcctatttag gtgacactat     60

agaatcgtcg actctggacc ttggctgtca ctcagttgaa aagaggcgga gctgcagggg    120

tggttggctg aggctggctt ctgcgtggtg cagctgcgca cgtgtttcag ccggcagcgc    180

tttaagattt ccggggatgg aatccgaaat ggaaacgcag agcgccgggg cagaggaggg    240

ctttacccag gtcacccgca agggtggccg acgggcgaag aaacgacagg ctgaacagct    300

gtccgcagca ggagagggcg gggatgcggg ccgcatggac acagaggagg ccaggccggc    360

gaagaggccc gtcttcccac ccctctgtgg ggacgggctc ctgagtggga aagaagaaac    420

aaggaaaatt ccagtcccag ctaacagata cacaccattg aaagaaaact ggatgaagat    480

atttactcct attgtggaac atttgggact tcagatacgc tttaacttga aatcaaggaa    540

tgtagaaatc aggacttgta aggaaaccaa ggatgttagt gctctgacaa aagcagctga    600

ttttgtgaaa gcttttattc tcggctttca ggtggaggat gcacttgccc tcatcaggtt    660

ggatgacctc ttcctagagt cttttgaaat tacagatgtt aaacccctaa agggagacca    720

tctatccagg gcaataggaa gaatcgctgg caaaggagga aaaacaaatt caccatagag    780

aatgtgacac ggaccaggat agttttggct gatgtngaag tcacatcctt ggctccttca    840

aatatca                                                              847


<210>  320
<211>  880
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (656)..(656)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (693)..(693)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (716)..(716)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (750)..(750)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (783)..(783)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (785)..(785)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (794)..(794)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (802)..(803)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (806)..(806)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (810)..(810)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (812)..(812)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (814)..(814)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (821)..(821)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (829)..(830)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (837)..(837)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (859)..(859)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (863)..(863)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (873)..(874)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (878)..(878)
<223>  n is a, c, g, or t

<400>  320
nnntagagag aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgcccacgc gtccgccgag ccggaggggg    120

gaaacggcgc ccgccgcccg cccggagccc gcgagcaacc ccagtccccc ccacccgcgc    180

gtggcggcgc cggctcccta gccaccgcgg ccccaccctc ttccggcctc agctgtccgg    240

gctgccttcg cctccgcctg tggatgctgc gcctctccga acgcaacatg aaggtgctcc    300

ttgccgccgc cctcatcgcg gggtccgtct tcttcctgct gctgccggga ccttctgcgg    360

ccgatgagaa gaagaagggg cccaaagtca ccgtcaaggt gtattttgac ctacgaattg    420

gagatgaaga tgtaggccgg gtgatctttg gtctcttcgg aaagactgtt ccaaaaacag    480

tggataattt tgtggcctta gctacaggag agaaaggatt tggctacaaa aacagcaaat    540

tccatcgtgt aatcaaggac ttcatgatcc agggcggaga cttcaccagg ggagatggca    600

caggaggaaa gagcatctac ggtgagcgct tccccgatga gaacttcaaa ctgaancact    660

acgggcctgg ctgggtgagc atggccaacg cangcaaaga caccaacggc tcccanttct    720

tcatcacgac agtcaagaca gcctggctan atggcaagca tgtggtgttt ggcaaagttc    780

tananggcat gtangtggtg cnnaangtgn anancaccaa naaagacann ccggganaaa    840

acccctgaag gatgtgatna tcncaaactg cgnnaaantt                          880


<210>  321
<211>  738
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (499)..(500)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (510)..(510)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (557)..(557)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (560)..(560)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (591)..(591)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (594)..(594)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (644)..(644)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (649)..(649)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (657)..(657)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (668)..(668)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (671)..(671)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (685)..(685)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (695)..(695)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (698)..(698)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (711)..(711)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (714)..(714)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (716)..(717)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (720)..(721)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (723)..(723)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (726)..(726)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (732)..(732)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (734)..(734)
<223>  n is a, c, g, or t

<400>  321
nanttagaga aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgccaagga ccacgggggc ggcggcggcg    120

gtggcaaaga ccagcagcag cagcagcagg aggcaccttt aggcccgggt cccaagtttt    180

gcaaagccgg ccccctccac cactacccat ccccctcccc ggaaagcagc aacccatccg    240

ctgccgccgg cggcagcagc gcgaagccat ccacagactt ccacaacctg gccagggagc    300

tggaaaactc ccggggaggc agcagctgct ccccagccca gagcctcagc agcggtagcg    360

gcagcggcgg cggcggcggc caccaggagg cggagctgag tcccgacggc atcgccacgg    420

gcggcggcaa aggaaagagg aaattcccgg aggaggcggc ggagggcggc ggtggcgctg    480

gtctggtagg gggccgggnn cgcttcgtan agcggcccct cccggcctcc aaggaggatc    540

tggtgtgcac accgcancan taccgagcct cgggcagcta cttcggcctg naanagaacg    600

gccgcctctt cgcgccgcca agtcccgaga cgggcgaggc gaancgcanc gccttcntgg    660

aggtgaanaa ngctgcccgc gcggncagcc tgcanganga ggggacagcc nacngnncgn    720

nantcncctc cnangacc                                                  738


<210>  322
<211>  1179
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (3)..(4)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (676)..(676)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (732)..(732)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (811)..(811)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (820)..(820)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (822)..(822)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (870)..(870)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (920)..(920)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (948)..(948)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (964)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (968)..(968)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (971)..(971)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (974)..(974)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (978)..(978)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (983)..(983)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1003)..(1003)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1013)..(1013)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1032)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1074)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1083)..(1083)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1086)..(1087)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1090)..(1090)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1102)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1109)..(1109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1121)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1141)..(1141)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1155)..(1155)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1176)..(1176)
<223>  n is a, c, g, or t

<400>  322
ganntagagg agaattaact atgagaggat cgcatcacca tcaccatcac ggatcctatt     60

taggtgacac tatagaatcg tcgacccacg cgtccgccca cgcgatccga agagatcgag    120

ctccctggct gccggctcgc cttctgcgtg gagttctcgc ggtctgggtt tcgctgtctg    180

ctcttggccc ggggtcattt tgtcggcgtc gggtgccctc tcttgcccag ctggggcaca    240

gcgaggcggc cccttctccc gacgacgttc gatggagtag ggtcccagac cgttgtcccg    300

aagagcgaga tcgagcttgg ccccctcccc cccctccttc cctccctcct tccttccgcc    360

gcaacatggc taacaacagc cccgcgctga caggcaactc gcagccgcag caccaggcgg    420

ctgcagctgc ggctcagcaa cagcagcagt gcggcggcgg cggcgctacc aagccggcgg    480

tctccggcaa gcagggcaat gtgctcccgc tctggggcaa cgagaagacc atgaacctca    540

accccatgat cctgaccaac atcctgtcgt cgccttactt caaagtacag ctctacgagc    600

tcaagaccta ccacgaggtg gtggacgaga tctactttaa ggtcacgcac gttgaaccat    660

gggagaaagg aagcangaaa acagcgggcc agacagggat gtgcggaggg gttcgaggtg    720

ttggaacagg angaattgtt tctacagcat tttgcctgtt atacaaatta tttaccctga    780

agttaactcg aaagcaagtg atgggtctta naacacacan anactctcca tatattaaag    840

cgcttggaat tatgtaaaat aaaaatatan acagcccccc taaaaaaatc tggtgggaac    900

tgggtttgaa aatccttccn ttgaagaatg aaaaaggaac ctaaaatntg aaaggcctgg    960

ttgnaagnct ngtntaanga acnattngga aaaaatgctt aanaantttt ttntncaaaa   1020

aaactgggaa gnggtttttn taactttgtt ttccaaaaaa ttcaaatttc caanttcaaa   1080

aanaannttn gattcaanaa anttaaaanc cccgacctta naaaaaaaca aaaaaaaaaa   1140

ngggaaagga aggtncttaa aaaaaaaaaa caaaanttt                          1179


<210>  323
<211>  1057
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (17)..(17)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (36)..(36)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (72)..(72)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (761)..(761)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (865)..(865)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (925)..(925)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (952)..(952)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (954)..(954)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (970)..(970)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (991)..(991)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1002)..(1002)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1023)..(1024)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1028)..(1028)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1038)..(1057)
<223>  n is a, c, g, or t

<400>  323
attagagaga attactntga gaggatcgca tccccntcat ccatcacgga tcctatttag     60

gtgacactat anaatcgtcg acccacgcgt ccggtaagat cccctgcaac tggaagaagc    120

aatttggcgc ggagtgcaaa taccagttcc aggcctgggg agaatgtgac ctgaacacag    180

ccctgaagac cagaactgga agtctgaagc gagccctgca caatgccgaa tgccagaaga    240

ctgtcaccat ctccaagccc tgtggcaaac tgaccaagcc caaacctcaa gcagaatcta    300

agaagaagaa aaaggaaggc aagaaacagg agaagatgct ggattaaaag atgtcacctg    360

tggaacataa aaaggacatc agcaaacagg atcagttaac tattgcattt atatgtaccg    420

taggctttgt attcaaaaat tatctatagc taagtacaca ataagcaaaa acaaaaagaa    480

aagaaaattt ttgtagtagc gttttttaaa tgtatactat agtaccagta ggggcttata    540

ataaaggact gtaatcttat ttaggaagtt gacttatagt acatgataaa tgatagacaa    600

ttgaggtaag ttttttgaaa ttatgtgaca ttttacatta aatttttttt acattttttg    660

ggcagcaatt taaatgttat gactatgtaa actacttctc ttgttaggta atttttttca    720

cctagatttt tttcccaatt gagaaaaata tatactaaac naaaatagca ataaaacata    780

atcactctat ttgaagaaaa tatcttgttt tctgccaata gattttttaa aatgtagtca    840

gcaaaatggg ggtggggaag cagancatgt cctagttcaa tgttgacttt tttttttttt    900

ttaaagaaaa agcttttaag acctnaaaat ttcttttccc ttttggcaaa ancnttttgt    960

tttcttggtn aaaattnttt ttccctcctg naggaaaaaa antacttagg gaaaataaan   1020

tcnngggnga tgcgggannn nnnnnnnnnn nnnnnnn                            1057


<210>  324
<211>  1040
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (14)..(15)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (37)..(37)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (823)..(823)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (837)..(837)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (840)..(840)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (843)..(843)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (852)..(852)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (857)..(857)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (862)..(862)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (868)..(868)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (898)..(898)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (909)..(909)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (916)..(916)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (928)..(928)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (933)..(933)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (935)..(935)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (938)..(939)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (952)..(952)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (963)..(963)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (967)..(967)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (981)..(981)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (986)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (990)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (998)..(998)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1002)..(1002)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1017)..(1017)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1023)..(1023)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1032)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<400>  324
atagaganaa ttannctatg agaggatcgc atcatcntca tccatcacgg aatcctattt     60

agggtgacac tatattaatc gtcgacccac gcgtccgccc ggatctcctg gctctcatcc    120

ctggactggg aagccaaaga gactcaggtg tcagggaccc tggccggaac tgtcactgtc    180

accagccgct tcaccttggt gccctcgggc cgagcagatg gtgtcacggt cacctgcaaa    240

gtggagcatg agagcttcga ggaaccagcc ctgatacctg tgaccctctc tgtacgctac    300

cctcctgaag tgtccatctc cggctatgat gacaactggt acctcggccg tactgatgcc    360

accctgagct gtgacgtccg cagcaaccca gagcccacgg gctatgactg gagcacgacc    420

tcaggcacct tcccgacctc cgcagtggcc cagggctccc agctggtcat ccacgcagtg    480

gacagtctgt tcaataccac cttcgtctgc acagtcacca atgccgtggg catgggccgc    540

gctgagcagg tcatctttgt ccgagaaacc cccagggcct cgccccgaga tgtgggcccg    600

ctggtgtggg gggccgtggg ggggacactg ctggtgctgc tgcttctggc tggggggtcc    660

ttggccttca tcctgctgag ggtgaggagg aggaggaaga gccctggagg agcaggagga    720

ggagccagtg gcgacggggg attctacgat ccgaaagctc aggtgttggg aaatggggac    780

cccgtcttct ggacaccagt agtccctggt cccatggaac canatggcaa ggatgangan    840

gangaggagg angaaanaaa angcaaanaa aggcctcatg ttgcctccac ccccccanca    900

attcgaggna tgaaanggaa atccccanct ggnanggnnt ccctcatctt cncggngggg    960

cantttnatg tgtgacctgg nacncnnacn gaaaaacnga anccngggcc cgggccnttc   1020

ccnccccccg anctgaacan                                               1040


<210>  325
<211>  927
<212>  DNA
<213>  Homo sapiens

<400>  325
tgagaggtcg catcaccatc accatcacgg atcctattta ggtgacacta tagaatcgtc     60

gacccacgcg tccggctccg ggaatgagcc ggtgccatct gtgggggctt tgggccaggg    120

gtctccggac agcatgagcg tgggcttcat cggcgctggc cagctggctt ttgccctggc    180

caagggcttc acagcagcag gcgtcttggc tgcccacaag ataatggcta gctccccaga    240

catggacctg gccacagttt ctgctctcag gaagatgggg gtgaagttga caccccacaa    300

caaggagacg gtgcagcaca gtgatgtgct cttcctggct gtgaagccac acatcatccc    360

cttcatcctg gatgaaatag gcgccgacat tgaggacaga cacattgtgg tgtcctgcgc    420

ggccggcgtc accatcagct ccattgagaa gaagctgtca gcgtttcggc cagcccccag    480

ggtcatccgc tgcatgacca acactccagt cgtggtgcgg gagggggcca ccgtgtatgc    540

cacaggcacg cacgcccagg tggaggacgg gaggctcatg gagcagctgc tgagcagcgt    600

gggcttctgc acggaggtgg aagaggacct gattgatgcc gtcacggggc tcagtggcag    660

cggccccgcc tacgcattca cagccctgga tgccctggct gatgggggtg tgaagatggg    720

acttccaagg cgcctggcag tccgcctcgg ggcccaggcc ctcctggggg ctgccaagat    780

gctgctgcac tcagaacagc acccaggcca gctcaaggga caacgtcagc tctcctggtg    840

gggccaccat ccatgccttg catgtgctgg agagtggggg cttccgctcc ctgctcatca    900

acgctgtgga ggcctcctgc atccgca                                        927


<210>  326
<211>  1179
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (819)..(819)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (870)..(870)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (872)..(872)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (910)..(910)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (913)..(914)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (929)..(929)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (953)..(953)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (959)..(960)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (962)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (972)..(972)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (979)..(979)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (983)..(983)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (995)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1004)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1010)..(1010)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1018)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1025)..(1025)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1038)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1047)..(1047)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1060)..(1060)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1075)..(1075)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1080)..(1082)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1088)..(1089)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1112)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1117)..(1117)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1127)..(1127)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1137)..(1137)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1139)..(1139)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1141)..(1141)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1148)..(1148)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1152)..(1152)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1156)..(1156)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1159)..(1159)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1166)..(1166)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1169)..(1169)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1173)..(1173)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1176)..(1176)
<223>  n is a, c, g, or t

<400>  326
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg ccagctccac cagcacgtgc agcagctaca    120

cctgggcacc cggctgcctg tggtggtcgt ggccaacaaa gctgacctgt tgcacatcaa    180

acaggttgac cctcagcttg gactgcagct agccagcatg ctaggctgct cattctatga    240

agtgtctgtc agtgaaaatt ataatgatgt ctacagcgcc ttccacgtcc tctgtaaaga    300

ggtcagtcac aaacagcagc ctagcagtac acccgagaag cgaagaacct ccctcattcc    360

caggcccaag tcacccaaca tgcaggacct gaagaggagg tttaagcaag ccctctctgc    420

caaagtgagg actgtcacct ccgtctgaag caggaggagc actcaagggg gtttggtctt    480

cccaggaaga gggcctgagg ttctcctagt gcaggaacgt tgaatattgg caatgattcc    540

tggttccaga aagggctgga gcagaagggc caagagggcc tgtggaactg ctacagaaaa    600

ggaagtgttg ttctgagcag ggggacagga ttgatgaggc ttgaaagagc ccactgagcc    660

actctctgaa tatgtgaaat gtactctgtg tcttttcctt tagagtgggg agggggcata    720

atcgtttcgg tttctgcatt caactacctt gtaaatggtg gtccgttgca gtttcaccaa    780

atgtattgat gtgatttaca gtgggaatga aagaaacana taaggcattg ataggctttc    840

cttttttccc cccttttttt ccttttttcn cntttcctcc tttccttttc cccccttttt    900

tcccccaaan aannaaaaat tggcttttnc cccttaacca aaaatgaatt tgntaaacnn    960

tngaaacacc tnattcttna aanaatggcc ctttntaaaa cctnnaaagn aaaccccnaa   1020

atttnttttt ttttttgnaa aaaaaangaa aaatcccccn taccccccaa aaaanaggtn   1080

nnattttnng ggccccaaaa ntattttttt anacccnaaa aattggnaaa ctcctcngng   1140

nttaaaanaa ancctntgnt tccccnccnc canganata                          1179


<210>  327
<211>  905
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (14)..(14)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (18)..(18)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (28)..(28)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (668)..(668)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (787)..(787)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (800)..(800)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (812)..(812)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (843)..(843)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (856)..(856)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (861)..(862)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (864)..(864)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (866)..(866)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (870)..(871)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (875)..(875)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (878)..(878)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (886)..(886)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (889)..(889)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (896)..(896)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (900)..(900)
<223>  n is a, c, g, or t

<400>  327
ganagagaga ttantatnag aggatcgnat caccagtcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cgggagcaca gaaaatggtt ctgccccctc    120

cacagctccc acagaccaga gccggccacc gttggagcac gtggaccagc acctgttcac    180

gctgccgcag ggctacggac agtttgcttt cggcatcttc gatgacagct tcgagatccc    240

cacgttccct cctggggcgc aggctgacga cggcagggac cctgagagcc ggcgggagag    300

agaccatccg tcccggcacc ggtacggcgc ccgacagccc cgcgcccgcc tcaccacgcg    360

gcgggccacc ggccggcacg aaggcgtccc cacgctggaa gggatcatcc agcagctcgt    420

caacggcatc atcacgcccg ccaccatccc cagcctgggc ccctggggag tcctgcactc    480

aaaccctatg gactacgcct ggggggccaa cggcctggat gccatcatca cacagctcct    540

caatcagttt gaaaacacag gccccccacc ggcagataaa gagaaaatcc aggccctccc    600

caccgtcccc gtcactgagg agcacgtagg ctccgggctc gagtgccctg tgtgcaagga    660

cgactacncg ctgggtgagc gtgtgcggca gctgccctgc aaccacctgt tccacgacgg    720

ctgcatcgtg ccctggctgg agcagcacga cagctgcccc gtctgccgaa aaagcctcac    780

gggacanaaa cacggccacn aacccccctg gnctcactgg ggtgagcttt ctcctcctcg    840

tcntcatcgt ccttcntcca nntngnccan naacnaanaa cgccanaanc aactcntgan    900

cccac                                                                905


<210>  328
<211>  1126
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (881)..(881)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (915)..(915)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (919)..(919)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (947)..(947)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (952)..(952)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (969)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (973)..(973)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (975)..(975)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (986)..(986)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (989)..(989)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (999)..(999)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1008)..(1008)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1033)..(1033)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1041)..(1042)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1053)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1055)..(1055)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1078)..(1078)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1091)..(1091)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1093)..(1093)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1113)..(1113)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1117)..(1117)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1120)..(1121)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1124)..(1124)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1126)..(1126)
<223>  n is a, c, g, or t

<400>  328
ganttagaga ganttaacta tgagaggatc gcatcaccat caccagtcac gggatcctat     60

ttaggtgaca ctatagaatc gtcgacccac gcgtccgtga aggtccagga gcagatggcc    120

aactgcccca agttcgtccc cgtggtgccc acatcacagc ctatccccag caacatcccc    180

aacaggtcca ccttcgcctg cccgtactgt ggtgcccgca acctggacca gcaggagctg    240

gtgaagcact gtgtggaaag ccaccgcagc gaccccaacc gcgtggtgtg ccccatctgc    300

tcggcaatgc cctgggggga ccccagctac aagagcgcca acttcctgca gcacctgctt    360

caccgacaca agttctccta cgacaccttt gtggactaca gtattgacga ggaggccgcc    420

ttccaggctg ctctggccct gtctctctct gagaactgaa gggaagcgca gccacccgcc    480

tgcgtctggg gtcagggatg tccccgctcc tgtgtcgcac ctggcacctg ctcgggagcg    540

cacctcaccg gactgagctc acaggaggag cctgcacccg cgcagaaggg gagccggggc    600

cgagcctccg ggcctgaata cgggccagcc gccgaggccg ccagagcagg gccgcctggt    660

cccaccggcg tcgctgggtt cttcggtgct tctggccgag caggcggcct acttgggcag    720

ggctggacgc tgggacctgg agctgccgcc gtctcttcaa agccatgata ccccctcgtg    780

ggaagaaggg accgacgcgc gagtcgcgct ccgcagtcga gccgggagga acccaggctg    840

ctgccctgcc cagcccgacc ctgcccccgc cccgcttcac nttgcgcatt tggtactggc    900

ttttgtgata cttangaanc ctggcatctt tttctatatt atccagnggg anaatctttt    960

tcacgtttna tanancaaaa ananancant tactcttcnt attgnaanat ctgtgtttga   1020

ctaagaataa aantattttt nngggaaaat ttnanaaaat tatatttttt aaaaaaanaa   1080

atcaaaaaaa ncnttngggg gatnggggca agnatgnaan naanan                  1126


<210>  329
<211>  816
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (693)..(693)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (729)..(729)
<223>  n is a, c, g, or t

<400>  329
tgagaggtcg catcaccatc accatcacgg atcctattta ggtgacacta tagaatcgtc     60

gactctggac cttggctgtc actcagttga gcaactagag aagactttcc aggaagagga    120

acagcatctt cagggtttgg agatagccca aggagaaaag gacctgaagc aacagctggc    180

ccaggctctg caggaggaag agaaggagaa gatgcaagca cagaaggaag aagttcttag    240

ccacatgaat gatgtgctag agaatgagct ccaatgtatt atttgttcag aatacttcat    300

tgaggctgtc accttgaact gtgcccacag tttctgctcc tactgtatca atgaatggat    360

gaagcggaag atagaatgcc ccatttgtcg gaaggacatt aagtccaaaa cgtactcttt    420

ggttctggac aattgcatta ataagatggt aaataatctg agctcagaag tgaaagaacg    480

acgaattgtt ctcattaggg aacgaaaagc aaagagattg ttctgaagac cgtgctctaa    540

gggcatttga aagactgcca ggtagtgcga gcctgagatg gtctggagga ttctctctag    600

ccgtgactcc gctgctctga aggtcaactg agaagtcttg tgggacagag acttgagtta    660

ggaagccctc agtcacttgc cttccacggt ggncagccct gctgccatca ttggctgaag    720

caccaccang attcacggca ccccactgct tcagggtact tcgtaaactc tgcctcacta    780

catgtcgaaa gagttatttg agttctcttc cggttt                              816


<210>  330
<211>  1134
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (878)..(878)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (880)..(880)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (904)..(904)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (941)..(941)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (979)..(979)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (986)..(986)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (999)..(999)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1002)..(1002)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1008)..(1008)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1012)..(1012)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1017)..(1017)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1029)..(1029)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1079)..(1079)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1084)..(1084)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1087)..(1089)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1100)..(1102)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1108)..(1108)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1112)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1118)..(1118)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1121)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1128)..(1128)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1130)..(1130)
<223>  n is a, c, g, or t

<400>  330
naantagaga aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccggctcaat tcagcaaaaa acagatctga    120

tgggatttgg ttattctcta cctgatcaga acaaaggtaa caatggtggg aaaggtggaa    180

aaaagaagaa aaataaaaac tcttctaaac cacagaaaaa caatggatcc acttgggcca    240

atgtccctct acctcccccc ccagtccagc cccttcctgg cacggagctg gaacactatg    300

cagtggaaca acaagaaaat ggctatgaca gtgatagctg gtgcccacca ttgccagtac    360

aaacttactt acaccaaggt ctggaagatg aactggaaga agatgatgat agggtcccaa    420

cacctcctgt tcgaggcgtg gcttcttctc ctgctatctc ctttggacag cagtccactg    480

caactcttac tccatcccca cgggaagaga tgcaacccat gctgcaggct cacctggatg    540

agttgacaag agcctatcag tttgatatag caaaacaaac atggcacatt caaagcaata    600

atcaacctcc acagcctcca gttccaccgt taggttatgt gtctggagcc ttgatttctg    660

atttggaaac ggatgttgca gatgatgatg ccgacgacga agaggaagct ttagaaatcc    720

ccaggcccct gagagcactg gaccagactc ctggatccag catggacaat ctagacagct    780

ctgtgacagg aaaagccttt acctcctctc aaagacctcg acctaccagc ccattttcta    840

ctgacagtaa caccagtgca gccctgagtc aaagtcanan gcctcggccc actaaaaaac    900

acangggagg gcggatggac caacaaccca gcattgcctc ntcgaaggga aggaatgaca    960

gatgaggagg ccttggngnc ctanancagg cccagtttnc cnatctcnag gnggccncag   1020

ctccatcang aaaagcttct tctaagggat tcccctggga cctaggaaaa acccaaggng   1080

tttnaannna gggcccccan nncaatgncc ancgaacntt nttgaaanan gaaa         1134


<210>  331
<211>  978
<212>  DNA
<213>  Homo sapiens

<400>  331
taactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt gacactatag     60

aatcgtcgac ccacgcgtcc ggcagctcag agccagagga gtggtgcccg ccaatgcctg    120

agagaagtca cctgacggag cccagctcca gtggagggtg cctggtcacc ccatcccgaa    180

gggaaacccc ctctcccaca ccttcctatg gacagcagtc cacagccact cttacaccct    240

cacctcctga ccctccccag cccccaactg acatgcccca tctccatcag atgcccagga    300

gggtgcccct tgggccgagt tcccctctca gtgtatccca gcccatgctg ggcatccgtg    360

aagcgaggcc tgctggcttg ggtgctggcc ctgcagcctc accccacctc agccccagtc    420

ctgcccctag cacagccagc agtgccccag gcagaacctg gcaggggaat ggggagatga    480

ctcccccact tcaaggaccc cgtgctcgat tccggaagaa acccaaggct cttccctaca    540

ggagggagaa cagtcctggg gacttgcccc caccaccctt gccaccgcca gaggaagagg    600

cgagctgggc cctagagctg agggcagcag gcagcatgtc ctccctggag cgggagcgca    660

gtggggagag gaaagcggtc caggccgtgc ccctggcagc ccagcgggtg ctccacccag    720

atgaagaggc ctggctccca tacagcagac caagcttcct gtcccggggc cagggcacca    780

gcacatgttc cacggccggc agcaactctt ccaggggctc cagcagctct aggggctccc    840

ggggccctgg ccggagccgg agtcggagtc agagccggag ccagagccaa agggccagga    900

cagaaacgcc gagaggaacc aagatgaccc ttgttggggc attgagaata tcatgagtgc    960

cacggggaag gggagtag                                                  978


<210>  332
<211>  620
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (33)..(33)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (36)..(36)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (40)..(40)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (45)..(45)
<223>  n is a, c, g, or t

<400>  332
aatntaaaaa ttatttgctt tgtgagcgga tanatntatn gattnattgt gagcggataa     60

caatttacac agaattatta aagaggagaa attaactatg agaggatcgc atcaccatca    120

ccatcacgga tcctatttag gtgacactat agaatcgtcg acccacgcgt ccggcaaagt    180

ctctcgcgac accctgtacg aggcggtgcg ggaagtcctg cacgggaacc agcgcaagcg    240

ccgcaagttc ctggagacgg tggagttgca gatcagcttg aagaactatg atccccagaa    300

ggacaagcgc ttctcgggca ccgtcaggct taagtccact ccccgcccta agttctctgt    360

gtgtgtcctg ggggaccagc agcactgtga cgaggctaag gccgtggata tcccccacat    420

ggacatcgag gcgctgaaaa aactcaacaa gaataaaaaa ctggtcaaga agctggccaa    480

gaagtatgat gcgtttttgg cctcagagtc tctgatcaag cagattccac gaatcctcgg    540

cccaggttta aataaggcag gaaagttccc ttccctgctc acacacaacg aaaacatggt    600

ggccaaagtg gatgaggtga                                                620


<210>  333
<211>  436
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<400>  333
canttagaga gaattactat gagaggatcg catcaccatc accatcacgg atcctattta     60

ggtgacacta tagaatcgtc gacccacgcg tccgggaagc acaaaaaggg acagtcggaa    120

gaaattcaaa agaaaagaac ccgccgagca gtcaaattcc agagggccat tactggtgca    180

tctcttgctg atataatggc caagaggaat cagaaacctg aagttagaaa ggctcaacga    240

gaacaagcta tcagggctgc taaggaagca aaaaaggcta agcaagcatc taaaaagact    300

gcaatggctg ctgctaaggc acctacaaag gcagcaccta agcaaaagat tgtgaagcct    360

gtgaaagttt cagctccccg agttggtgga aaacgctaaa ctggcagatt agatttttaa    420

ataaagattg gattat                                                    436


<210>  334
<211>  1112
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (809)..(809)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (811)..(811)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (819)..(819)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (852)..(852)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (863)..(863)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (908)..(908)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (912)..(912)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (925)..(925)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (945)..(945)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (953)..(953)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (955)..(955)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (963)..(963)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (968)..(968)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (980)..(980)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (990)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (993)..(993)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (999)..(999)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1010)..(1010)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1017)..(1017)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1026)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1029)..(1029)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1043)..(1043)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1051)..(1052)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1062)..(1062)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1064)..(1064)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1066)..(1067)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1072)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1086)..(1086)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1109)..(1110)
<223>  n is a, c, g, or t

<400>  334
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg tggagaagag cgagtacttg agaaagaaga    120

ggaagaagat gatgatgaag atgaagatga agaagatgat gtgtcagagg gctctgaagt    180

gcccgagagt gaccgtcctg caggtgccca gcaccaccag cttaacggcg agcggggacc    240

tcagagtgcc aaggagaggg tcaaggagtg gaccccctgc ggaccgcacc agggccagga    300

tgaagggcgg gggccagccc cgggcagcgg cacccgccag gtgttctcca tggcagccat    360

gaacaaggaa gggggaacag cttctgttgc caccgggcca gactccccgt cccccgtgcc    420

tttgccccca ggcaaaccag ccctacctgg ggccgacggg accccctttg gctgtcctcc    480

cgggcgcaaa gagaagccat ctgatcccgt cgagtggacc gtgatggatg tcgtcgaata    540

ttttactgag gctggattcc cggagcaggc gacagctttc caagagcagg aaattgatgg    600

caaatctttg ctgctcatgc agcgcacaga tgtgctcacc ggcctgtcca tccgcctcgg    660

gccagccctg aaaatctacg agcaccacat caaggtgctt cagcaaggcc actttgagga    720

tgatgacccc gatggcttct taggctgagc gcccagcctc acccctgccc cagcccattc    780

cggcccccat ctcacccaag atcccccana ntccagganc tggacgggga caccctcagc    840

ccttcataac anattccaag ganagggcac cctcttgtcc ttatctttgc cccttgtgtc    900

tgtctcanac anatctgctc ctcancacgt cggtgtgggg agggnattgc tcntnaaccc    960

cangtggntg accctccccn cccntccngn acnttttang aaaaaaaaan tgaatgnggg   1020

gggttntcnt tccccaaaat ctnttccttt nnccaaattt tncngnnaaa nntttggatt   1080

gcctgntttt tttggggggg ggtttttcnn cc                                 1112


<210>  335
<211>  883
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (787)..(787)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (817)..(817)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (849)..(850)
<223>  n is a, c, g, or t

<400>  335
gatactatga gaggtcgcat caccatcacc atcacggatc ctatttaggt gacactatag     60

aatcgtcgac tctggacctt ggctgtcact cagttaaaaa aaatacttcg gaggacagcg    120

aaaacttccc atcaagttct aaaaagtctg aggagtggcc tgactggagt gaacctgagg    180

agcctgaaaa tcaaactgtc aacatacaga tttggcctag agaaccttgt gatgatgtca    240

agtcccagtg cactaccttg gatgtggaag agtcatcttg ggatgactgc gagcccagca    300

gcttagatac taaagtaaac ccaggaggtg gaatcactgc tacaaaacct gttacctcag    360

cggagcagaa gcctattcct gctttgcttt cactcactga agagtctatg ccttggaaat    420

caagcttacc ccaaaagatt agccttgtac aaagggggga tgacgcagac caaatcgagc    480

cgccaaaagt gtcatcacaa gaaaggcccc ttaaggttcc atcagaactt ggtttaggag    540

aggaattcac cattcaagta aaaaagaagc cagtaaaaga tcctgagatg gattggtttg    600

ctgatatgat cccagaaatt aagccttctg ctgcttttct tatattacct gaactgagga    660

cagaaatggt cccaaaaaag gatgatgtct ccccagtgat gcagttttcc tcaaatttgc    720

tgcagcagaa atactgaggg agagctgaag gctgggaaga gaaggggagc tgaactggga    780

agataantac tgtgacatag atgtgagtta actttangaa aaggattccc tttttaaaaa    840

aatcatacnn tcaaagcagc ttggacagaa aaccaaagtg cct                      883


<210>  336
<211>  1016
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (794)..(794)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (819)..(819)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (869)..(869)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (887)..(887)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (894)..(894)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (912)..(912)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (923)..(923)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (931)..(931)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (937)..(937)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (943)..(943)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (949)..(949)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (951)..(951)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (971)..(971)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (979)..(979)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (989)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (992)..(992)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (994)..(994)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (996)..(996)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1008)..(1008)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1012)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1016)
<223>  n is a, c, g, or t

<400>  336
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc ctccaccctg ccggctggag aggggcccaa    120

ggagggagag gctgtagtcc tgccagaagt ggagcctggc ctcaccgccc gggagcagga    180

ggccaccccc cgacccaggg agaccacaca gctcccgacc actcatcagg cctcaacgac    240

cacagccacc acggcccagg agcccgccac ctcccacccc cacagggaca tgcagcctgg    300

ccaccatgag acctcaaccc ctgcaggacc cagccaagct gaccttcaca ctccccacac    360

agaggatgga ggtccttctg ccaccgagag ggctgctgag gatggagcct ccagtcagct    420

cccagcagca gagggctctg gggagcagga cttcaccttt gaaacctcgg gggagaatac    480

ggctgtagtg gccgtggagc ctgaccgccg gaaccagtcc ccagtggatc agggggccac    540

gggggcctca cagggcctcc tggacaggaa agaggtgctg ggaggggtca ttgccggagg    600

cctcgtgggg ctcatctttg ctgtgtgcct ggtgggtttc atgctgtacc gcatgaagaa    660

gaaggacgaa ggcagctact ccttggagga gccgaaacaa gccaacggcg gggcctacca    720

gaagcccacc aaacaggagg aattctatgc ctgacgcggg agccatgcgc cccctccgcc    780

ctgccactca ctangccccc acttgcctct tccttgaana attgcaggcc ctggcctccc    840

ctgccaccag gccacctccc cagcattcna gcccttctgg tcgctcntgc ccanggaaat    900

cttggggtgt gntggaactc cantctgctt ntctganttt tgnctggana nttaagggca    960

ccaggggttt ntcgcatang ancttttcnn cnananccag aacctggnat nncaan       1016


<210>  337
<211>  634
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (5)..(5)
<223>  n is a, c, g, or t

<400>  337
tcganaatat aaaaaattat ttgctttgtg agcggataca atataataga ttaattgtga     60

gcggataaca atttacacag aattcattaa agaggagaaa ttaactatga gaggatcgca    120

tcaccatcac catcacggat cctatttagg tgacactata gaatcgtcga cccacgcgtc    180

cggtgccccg ccttcactgc gtcctctgct ggacagcatc gtcaacgcca caggagagct    240

cgcctggggg gtggacgaga ccctggccca gctggagaag gtgctgcacc tgtaccggag    300

cgggcagtat ctgcagaact ccacggcaag cagcagtacc gagtaccagt gtatcccaga    360

cagcaccatc ccccaggaag actaccgctg ctggccatcc taccaccacg ggagctgcct    420

cctttcagtg ttcaacctgg ctgaggctgt ggatgtctgt gagagccatg cccagtgtcg    480

ggcctttgtg gtcaccaacc agaccacctg gacaggtcgg cagctggtct ttttcaagac    540

tggatggagc caagtggtcc ctgatcccaa caagaccaca tatgtgaagg cctctggctg    600

acctatctga gggctcggct gaccagctga ctat                                634


<210>  338
<211>  1027
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (740)..(740)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (788)..(788)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (799)..(799)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (801)..(801)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (803)..(803)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (823)..(823)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (849)..(849)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (870)..(870)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (890)..(890)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (892)..(892)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (907)..(907)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (913)..(913)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (925)..(925)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (927)..(927)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (929)..(929)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (932)..(933)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (935)..(935)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (944)..(944)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (950)..(950)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (961)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (970)..(970)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (983)..(983)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(998)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1007)..(1007)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1010)..(1010)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1016)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1023)..(1024)
<223>  n is a, c, g, or t

<400>  338
cantagagag aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccggaaaagc catcgagctc aacccagcca    120

acgccgtcta tttctgcaac agagccgcag cctacagcaa actcggcaac tacgcaggcg    180

cggtgcagga ctgtgagcgg gccatctgca ttgacccggc ctacagcaag gcctacggca    240

ggatgggcct ggcgctctcc agcctcaaca agcacgtgga ggccgtggct tactacaaga    300

aggcgctgga gctggacccc gacaacgaga catacaagtc caacctcaag atagcggagc    360

tgaagctgcg ggaggccccc agccccacgg gaggcgtggg cagcttcgac atcgccggcc    420

tgctgaacaa ccctggcttc atgagcatgg cttcgaacct aatgaacaat ccccagattc    480

agcagctcat gtccggcatg atttcgggtg gcaacaaccc cttgggaact cccggcacca    540

gcccctcgca gaacgacctg gccagcctca tccaggcggg ccagcagttt gcccagcaga    600

tgcagcagca gaacccagag ttgatagagc agctcaggag ccagatccgg agtcggacgc    660

ccagcgccag caacgacgac cagcaggagt gacgctgcct gctcccggtg tgaccgcgtc    720

cttccctggc cgacccgaan gaagccttct ggttgtctgc cacttcctcc tgttggactg    780

cctgaaanag gggaaaaana nanacctcgg acctgcatgt cangatggat tttccccttt    840

tatctctgnc ctcctccact ccctttttgn aactccctta cagcccccan ancctttttg    900

aaacganagc cancaagctg aacanananc annancgact tccnttccan cccccaaaaa    960

nntcggtcan ttgagtgttt tcnaaaatcc tgggggnntt cccgggnccn cttttnaaaa   1020

aannggg                                                             1027


<210>  339
<211>  1270
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (890)..(890)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (934)..(934)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (949)..(949)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (986)..(986)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (992)..(992)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1000)..(1000)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1019)..(1019)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1022)..(1022)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1050)..(1050)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1064)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1102)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1112)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1117)..(1117)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1125)..(1125)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1133)..(1133)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1143)..(1143)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1145)..(1145)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1149)..(1149)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1156)..(1156)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1159)..(1159)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1185)..(1185)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1191)..(1191)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1204)..(1204)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1218)..(1218)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1220)..(1222)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1227)..(1229)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1237)..(1237)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1239)..(1239)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1242)..(1243)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1252)..(1252)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1258)..(1258)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1261)..(1261)
<223>  n is a, c, g, or t

<400>  339
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg catcttgaac attgttaaag aaggacagat    120

ctctctcctg ccacacctag ctgcagacaa tctagacaaa attcacgacg aaaatggaaa    180

caatctatta catattgcgg cgtcacaggg acacgcagag tgtctacagc acctcacttc    240

tttgatggga gaagactgcc tcaatgagcg caacactgag aagttgactc cagcaggcct    300

ggccattaag aatggtcagt tggagtgcgt acgctggatg gtgagcgaaa cagaagccat    360

tgcagaactg agttgttcta aggattttcc aagccttatt cattacgcag gttgctatgg    420

ccaggaaaag attcttctgt ggcttcttca gtttatgcaa gaacagggca tctcgttgga    480

tgaagtagac caggatggca acagtgccgt tcacgtagcc tcacagcatg gctaccttgg    540

atgcatacag accttggttg aatatggagc aaatgtcacc atgcagaacc acgctgggga    600

aaagccctcc cagagcgccg agcggcaggg gcacaccctg tgctccaggt acctggtggt    660

ggtggagacc tgcatgtcgc tggcctctca agtggtgaag ttaaccaagc agctaaagga    720

acaaacagta gaacgtgtca cgctgcagaa ccaactccaa caatttctag aagcccagaa    780

atcagagggc aagtcactcc cttcttcacc cagttcacca tcctcacctg cctccagaaa    840

gtcccagtgg aatctccaga tgcagatgat gattctgtag ccaaaagcan gccaggagtc    900

caagagggga ttcaggttct tggaagcctg tcancctcca ccgggctana ccaagcaaaa    960

atgaanattc tgataaatct tacncngtta tngggaaagn aatctcaaaa atgtctgcnc   1020

cnagaaaaaa ctgtccttgg aatcccggan tgctcaggct cccnnaaaaa attttaaaaa   1080

atccccctgg aaaaaaggga anctgaaatt ancccgnctg aaaanctgat gcnaaggtcc   1140

tgnanggant cgaacnaanc tccaaaactt taagacccca aaaanccccg ngggaaggtg   1200

accnaccagg cccccccntn nnaaaannna aaaaatngna cnnccaaaac cngcccgnaa   1260

naaaaacccc                                                          1270


<210>  340
<211>  1087
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (917)..(917)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (934)..(934)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (953)..(953)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (960)..(960)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (992)..(992)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1027)..(1027)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1031)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1043)..(1043)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1049)..(1049)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1064)..(1064)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1087)..(1087)
<223>  n is a, c, g, or t

<400>  340
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc ccacgcgtcc gcggacctac tgggctccat    120

cctgagctcc atggagaagc cacccagcct cggtgaccag gagactcggc gcaaggcccg    180

agaacaggcc gcccgcctga agaaactaca agagcaagag aaacaacaga aagtggagtt    240

tcgtaaaagg atggagaagg aggtgtcaga tttcattcaa gacagtgggc agatcaagaa    300

aaagtttcag ccaatgaaca agatcgagag gagcatacta catgatgtgg tggaagtggc    360

tggcctgaca tccttctcct ttggggaaga tgatgactgt cgctatgtca tgatcttcaa    420

aaaggagttt gcaccctcag atgaagagct agactcttac cgtcgtggag aggaatggga    480

cccccagaag gctgaggaga agcggaagct gaaggagctg gcccagaggc aagaggagga    540

ggcagcccag caggggcctg tggtggtgag ccctgccagc gactacaagg acaagtacag    600

ccacctcatc ggcaagggag cagccaaaga cgcagcccac atgctacagg ccaataagac    660

ctacggctgt gtgcccgtgg ccaataagag ggacacacgc tccattgaag aggctatgaa    720

tgagatcaga gccaagaagc gtctgcggca gagtggggaa gagttgccgc caacctccta    780

ggcgccccgc ccagctccct ttgacccctg gggcagggca gggggcaggg aaagacaagg    840

ctgctgctat tagagcccat cctggagccc cacctctgaa ccacctccta ccagctgtcc    900

ctcaggctgg gggaaancag gtgttgattt gtcnccgttg gagcttggat atntgcctgn    960

catgtgtgtg tgtgtgtgaa antgtgaatg cncaggtggg tatttatctg tattattccc   1020

cgttctngga nttttcttcc ccntggggnc tggggtactt tacnttcaat aaatactgtt   1080

taacccn                                                             1087


<210>  341
<211>  1147
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (769)..(769)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (794)..(794)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (804)..(804)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (836)..(836)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (840)..(840)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (849)..(849)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (860)..(860)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (862)..(862)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (877)..(878)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (883)..(883)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (896)..(896)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (917)..(917)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (951)..(951)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (963)..(963)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (965)..(965)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (969)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (971)..(971)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (991)..(991)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (998)..(998)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1023)..(1023)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1025)..(1025)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1032)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1037)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1048)..(1048)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1052)..(1052)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1063)..(1063)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1065)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1073)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1081)..(1081)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1089)..(1090)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1102)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1105)..(1105)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1146)..(1146)
<223>  n is a, c, g, or t

<400>  341
naaatagaga nattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgattgccc gctccaccct ccacatgccc    120

tttctaactc ctcagttgac ctagggtccc caagccttgc cagtcacccc cggggcctgc    180

tgcagaaccg tggcctcaac aatgacagtc ctgagcggag gcgcaggcct ggccatggca    240

gcctgaccaa catcagccgg cacgactccc tcaagaagat cgacagccct cccattagaa    300

ggtccacgtc atcagggcaa tacacgggct tcaatgacca caagccactg gacccagaga    360

caattgctca ggatattgaa gaaacgatga acacagcttt gaatgaactc cgagaactgg    420

agagacagag cacagcaaag catgcccctg atgtggtgct ggataccctg gagcaagtga    480

aaaactctcc cacccctgcc acttccacgg aatctctcag ccctttgcac aacgttgccc    540

tcaggagctc cgagcctcag attcgacgta gcacgagctc ctccagtgac acaatgagta    600

ctttcaagcc tatggtggca cccagaatgg gcgtgcagct gaagcctcca gcccttaggc    660

caaaacctgc tgttcttcca aaaacaaatc ctaccatagg acctgccccc acctccccag    720

ggtccaacag acaagtcatg cacaatgtaa aaaccagccc aagcaaggnc ataaagggag    780

gtgacttaaa aaanaaaatg gatnagtgac aaaagtcact gatccataac tttccntaan    840

ttttgggcnt ataactggan ancttttggc ttttttnngt tgnccaaagg taatgnctga    900

aaataactta atttaancgg gcattggatt ttgaaatttt tttaaaaaaa ngggaaaatt    960

gtncntttna ngacaataaa aaancttaaa nttatttnaa aatccaatgg tggcnccctt   1020

gtnanagaaa gnaaannccn ctttcccnat tntaaaaanc ttncngtttt nnnttacccc   1080

nctttaatnn aaaaggttgg anctnaaggn aaaaaaaccc caaaggcccc ccccctttgg   1140

aaaaanc                                                             1147


<210>  342
<211>  1238
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (799)..(799)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (873)..(873)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (922)..(922)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (939)..(939)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (969)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1007)..(1007)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1011)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1017)..(1017)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1030)..(1030)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1049)..(1049)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1063)..(1064)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1066)..(1066)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1080)..(1080)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1083)..(1084)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1093)..(1093)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1100)..(1100)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1105)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1121)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1130)..(1131)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1134)..(1134)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1144)..(1144)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1171)..(1171)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1179)..(1179)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1183)..(1183)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1189)..(1189)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1193)..(1193)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1195)..(1195)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1219)..(1219)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1223)..(1223)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1235)..(1235)
<223>  n is a, c, g, or t

<400>  342
naatagagaa attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cggtagcctg ctaaaatcaa aagatttgtt    120

aaaacaaagg tacttatttg caaaagctgg ctatcctcta agaaggtctc agtctttacc    180

aaccacctta ttgagcccag taagggttgt gtcctctgtc aatgttcgat tatctccagg    240

aaaagagacc agatgcagcc caccttcctt cacctataag tacacacctg aagaggagca    300

ggaattggaa aagcgggtga tggaacatga tggtcagtct ttagttaaat cgaccatttt    360

catctctcca tcatctgtga agaaagaaga agccccccag agtgaggcgc cgcgggtgga    420

ggaatgccat catggaagga ctcctacctg ttcacggctt gctccaccac caatgtctca    480

gtctacctgt tcccttcatt ccatccactc tgagtggcaa gaaaggcccc tgtgtgagca    540

cacaagaact ctgagcactc acagtgttcc caacatatca ggggctactt gtagtgcctt    600

cgcttcccct ttcgggtgtc cttactcaca tagacatgcc acctaccctt accgagtgtg    660

ctctgtgaat cctccttcag ccatagaaat gcagttgcga agagtattac atgatattag    720

aaactcactg cagaatcttt cacagtaccc tatgatgaga ggacctgatc ctgctgctgc    780

tccatatagt actcagaant catctgttct acctctttat gaaaatactt ttcaggagct    840

ccaggtaatg aggcggagcc tgaatttgtt tanaacacaa atgatggatt tagaattggc    900

aatgctgcgt cagccaaacc anggtttatc atcatatgna ctgaggagga gaggtttgaa    960

gttgatcanc tcccagggtt tgaaaaattc agtccgaatg gaacttncag nacctgnaac   1020

tgcacctggn agaaccccct gctgggccnt gaaaaaaaac ttnngnggtg ggggaaggcn   1080

ttnncccttt cgnctcctcn gaannctggg gaaagggggg ncaaaaaaan nctnaaactg   1140

gccngccctt ccccttgaag gaaggaaccc ntccctgant tgngcgganc ccntnacctg   1200

aatcttaatg ggccgggant tgnaaaaagg gattnaaa                           1238


<210>  343
<211>  1154
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (878)..(878)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (902)..(902)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (907)..(907)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (925)..(925)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (983)..(983)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (990)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (996)..(996)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1012)..(1012)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1021)..(1021)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1033)..(1033)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1036)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1038)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1047)..(1047)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1062)..(1062)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1064)..(1064)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1073)..(1073)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1087)..(1087)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1093)..(1093)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1097)..(1097)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1118)..(1118)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1125)..(1125)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1133)..(1154)
<223>  n is a, c, g, or t

<400>  343
tagagaaaat taactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gctgccttgg acagcctccg ctgccgccgc    120

tgcatcatcg tgggcaatgg aggcgttctt gccaacaagt ctctggggtc acgaattgac    180

gactatgaca ttgtggtgag actgaattca gcaccagtga aaggctttga gaaggacgtg    240

ggcagcaaaa cgacactgcg catcacctac cccgagggcg ccatgcagcg gcctgagcag    300

tacgagcgcg attctctctt tgtcctcgcc ggcttcaagt ggcaggactt taagtggttg    360

aaatacatcg tctacaagga gagagtgagt gcatcggatg gcttctggaa atctgtggcc    420

actcgagtgc ccaaggagcc ccctgagatt cgaatcctca acccatattt catccaggag    480

gccgccttca ccctcattgg cctgcccttc aacaatggcc tcatgggccg ggggaacatc    540

cctacccttg gcagtgtggc agtgaccatg gcactacacg gctgtgacga ggtggcagtc    600

gcaggatttg gctatgacat gagcacaccc aacgcacccc tgcactacta tgagaccgtt    660

cgcatggcag ccatcaaaga gtcctggacg cacaatatcc agcgagagaa agagtttctg    720

cggaagctgg tgaaagctcg cgtcatcact gatctaagca gtggcatctg agtgggccca    780

gcacatggcc atagaggccc aggcaccacc aggagcagca gccagcacca cctacacagg    840

agtcttcaga cccagagaag gacggtgcca agggcccnag gggcagcaag gccttggtgg    900

ancagcnaga gctgtgcctg ctcancagcc agtctcaaaa aacaagcact cagcctcatt    960

cagcatgggt tccttgatgc canaaggncn agcagnctcc tggctgtgcc ancaggccca   1020

ncatgcaggg ggnggnanac tgggcancaa ggctgctgcc gnantccttc ncnatcaggg   1080

ttggggnata acnttgnaaa attnggaagg gggagggnag gaaanttttt ttnnnnnnnn   1140

nnnnnnnnnn nnnn                                                     1154


<210>  344
<211>  1374
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (6)..(7)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1154)..(1154)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1344)..(1344)
<223>  n is a, c, g, or t

<400>  344
tttaanngga tatactgact tacctataaa taggcgtatc acgaggccct ttcgtcttca     60

cctcgagaaa tcataaaaaa tttatttgct ttgtgagcgg ataacaatta taatagattc    120

aattgtgagc ggataacaat ttcacacaga attcattaaa gaggagaaat taactatgag    180

aggatcgcat caccatcacc atcacggtcg acccacgcgt ccgcccacgc gtccgcccac    240

gcgtccgaaa gccatcatcc tctccatcaa tctctgcagc cctgagttca cccaggctga    300

cagcaaggag agccgggacc tgcaggatcg cttgtcgcag atgaatgggc gctgggaccg    360

agtgtgctct ctgctggagg agtggcgggg cctgctgcag gatgccctga tgcagtgcca    420

gggtttccat gaaatgagcc atggtttgct tcttatgctg gagaacattg acagaaggaa    480

aaatgaaatt gtccctattg attctaacct tgatgcagag atacttcagg accatcacaa    540

acagcttatg caaataaagc atgagctgtt ggaatcccaa ctcagagtag cctctttgca    600

agacatgtct tgccaactac tggtgaatgc tgaaggaaca gactgtttag aagccaaaga    660

aaaagtccat gttattggaa atcggctcaa acttctcttg aaggaggtca gtcgtcatat    720

caaggaactg gagaaagtat taaacgtgtc aagtaatcag caggatttgc cttcctggtc    780

ttctgctgat gaactggaca cctcagggcc tgggagtccc actttcagga aagacacccc    840

aaacagaaca aaaacccccc gagggcaggg gaatctctcc cacctggaac cctcggcaac    900

aatcccccta tcaggtccca aaaaggtggc ccccaatccc cctttcgaaa ccagagccag    960

tccgacccaa cccaaatcca atcaaattca atcacataaa ttaatttcct gcgaaaaaac   1020

aatatacaat caaaacttcc tactaattta atacaacgct cgattcacac cgatataatt   1080

ttcagaaaca ataaacccca aacgctaaaa caaataacca ataaaacacc gtatatcaaa   1140

tcttcctatt ccanctacac taatcataca ctccattaac cccttctaac aaatcatttt   1200

atataccatc acaactcaat caccaaccta taacgatatt aattcaatac acaataaaaa   1260

ataccacata attacaatat aacaccaatt cagttaagcc catccaacca tcacacccaa   1320

gattctcacc cctacgacta atanaaatcg cgaatcagaa ctaagcaaaa caca         1374


<210>  345
<211>  814
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (9)..(10)
<223>  n is a, c, g, or t

<400>  345
tnanagggnn aattaactat gagaggatcg catcaccatc accatcacgg atcctattta     60

ggtgacacta tagaatcgtc gacccacgcg tccgtaaaga tgagtaaaag caaagatgat    120

gctcctcacg aactggagag ccagtttatc ttacgtctgc ctccagaata tgcctctact    180

gtgagaaggg cagtacagtc tggtcatgtc aacctcaagg acagactgac aattgagtta    240

catcctgatg ggcgtcatgg aatcgtcaga gtggaccgtg ttccattggc ctcaaaatta    300

gtagacctgc cctgtgttat ggaaagcttg aaaaccattg ataaaaaaac tttttacaag    360

acagctgata tctgtcagat gcttgtatcc acagttgatg gtgatctcta tcctcctgtg    420

gaggagccag ttgctagcac tgatcctaaa gcaagcaaga aaaaggataa ggacaaagag    480

aaaaagttta tctggaacca cggaattact ctgcctctaa agaatgtcag gaagagaagg    540

ttccggaaga cagcaaagaa gaaatatatt gaatctccag atgttgaaaa agaagtgaaa    600

cgattgctga gtacagatgc tgaagctgtt agtactcggt gggaaataat tgccgaagat    660

gaaacaaagg aggcagaaaa tcaaggcctg gatatctctt ctccaggaat gtctggtcac    720

aggcagggcc atgactcatt agaacatgat gagcttcggg agatattcaa tgacctcagc    780

agcagcagtg aggatgaaga tgagacccag catc                                814


<210>  346
<211>  488
<212>  DNA
<213>  Homo sapiens

<400>  346
tatgagaggt cgcatcacca tcaccatcac ggatcctatt taggtgacac tatagaatcg     60

tcgacccacg cgtccgggcg cgtggaggct gcagtcacgg tggcgcccgc ggggacggag    120

gagggaatga gtgaagagga gcaaggctcc ggcactacca cgggctgcgg gctgcctagt    180

atagagcaaa tgctggccgc caacccaggc aagaccccga tcagccttct gcaggagtat    240

gggaccagaa tagggaagac gcctgtgtac gaccttctca aagccgaggg ccaagcccac    300

cagcctaatt tcaccttccg ggtcaccgtt ggcgacacca gctgcactgg tcagggcccc    360

agcaagaagg cagccaagca caaggcagct gaggtggccc tcaaacacct caaagggggg    420

agcatgctgg agccggccct ggaggacagc agttcttttt ctcccctaga ctcttcactg    480

cctgagga                                                             488


<210>  347
<211>  1127
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (873)..(873)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (902)..(902)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (911)..(911)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (914)..(914)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (918)..(918)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (926)..(926)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (937)..(937)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (949)..(949)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (954)..(954)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (979)..(979)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (981)..(981)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1016)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1023)..(1023)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1041)..(1041)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1048)..(1048)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1051)..(1051)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1054)..(1054)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1062)..(1062)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1067)..(1067)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1075)..(1075)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1083)..(1083)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1094)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1099)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1107)..(1107)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1113)..(1113)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1115)..(1116)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1121)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1123)..(1125)
<223>  n is a, c, g, or t

<400>  347
agagaattac tatgagagga tcgcatcacc atcaccatca cggatcctat ttaggtgaca     60

ctatagaatc gtcgacccac gcgtccgtgc aggtagccgg ccggccgggg gtcgcgggta    120

tggccgaggc caggaagcgg cgggagctac ttcccctgat ctaccaccat ctgctgcggg    180

ctggctatgt gcgtgcggcg cgggaagtga aggagcagag cggccagaag tgtttcctgg    240

ctcagcccgt aacccttctg gacatctata cacactggca acaaacctca gagcttggtc    300

ggaagcggaa ggcagaggaa gatgcggcac tgcaagctaa gaaaacccgt gtgtcagacc    360

ccatcagcac ctcggagagc tcggaagagg aggaagaagc agaagccgaa accgccaaag    420

ccaccccaag actagcatct accaactcct cagtcctggg ggcggacttg ccatcaagca    480

tgaaagaaaa agccaaggca gagacagaga aagctggcaa gactgggaat tccatgccac    540

accctgccac tgggaagacg gtggccaacc ttctttctgg gaagtctccc aggaagtcag    600

cagagccctc agcaaatact acgttggtct cagaaactga ggaggagggc agcgtcccgg    660

cctttggagc tgctgccaag cctgggatgg tgtcagcggg ccaggccgac agctccagcg    720

aggacacctc cagctccagt gatgagacag acgtggaggg gaaaccctca gtaaaaccag    780

cccaggtcaa agcctcatca gtttctacta aggagtctcc agcaagaaag gcggccccag    840

cccctgggaa ggtgggggat gtgacacccc agntcaaagg aggggccctg cccccagcca    900

anagggccaa naanccanaa aaggantcaa aaagtantga ggagggatnt gaantgagga    960

ggaggccctt gcagggacnc naaaccaggt aaaggcntct gaaaaatttt caggtnaaan   1020

tgnctcaccc ctgcnaggga nccctggnaa nggntaccca cnccccntgg naggnagggc   1080

tgnaccttcc aacnaggnng gaacccnagn gantnnaaac ncnnnag                 1127


<210>  348
<211>  1131
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (788)..(788)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (808)..(808)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (834)..(834)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (869)..(869)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (880)..(880)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (882)..(882)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (890)..(890)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (897)..(897)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (908)..(908)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (928)..(928)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (932)..(932)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (942)..(943)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (952)..(952)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (958)..(958)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (964)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (967)..(967)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (969)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1012)..(1012)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1014)..(1014)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1016)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1034)..(1034)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1048)..(1048)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1050)..(1050)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1055)..(1055)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1065)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1074)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1079)..(1079)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1081)..(1081)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1083)..(1083)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1097)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1107)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1109)..(1109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1121)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1129)..(1129)
<223>  n is a, c, g, or t

<400>  348
aatagagaaa ttaactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cggcacctcc tcccgtcagg cgctttctcg    120

gacgccttgc ccagcgggcc gcccgacccc ctgcaccatg gaccccgctc gccccctggg    180

gctgtcgatt ctgctgcttt tcctgacgga ggctgcactg ggcgatgctg ctcaggagcc    240

aacaggaaat aacgcggaga tctgtctcct gcccctagac tacggaccct gccgggccct    300

acttctccgt tactactacg acaggtacac gcagagctgc cgccagttcc tgtacggggg    360

ctgcgagggc aacgccaaca atttctacac ctgggaggct tgcgacgatg cttgctggag    420

gatagaaaaa gttcccaaag tttgccggct gcaagtgagt gtggacgacc agtgtgaggg    480

gtccacagaa aagtatttct ttaatctaag ttccatgaca tgtgaaaaat tcttttccgg    540

tgggtgtcac cggaaccgga ttgagaacag gtttccagat gaagctactt gtatgggctt    600

ctgcgcacca aagaaaattc catcattttg ctacagtcca aaagatgagg gactgtgctc    660

tgccaatgtg actcgctatt attttaatcc aagatacaga acctgtgatg ctttcaccta    720

tactggctgt ggagggaatg acaataactt tgttagcagg gaggattgca aacgtgcatg    780

tgcaaaanct ttgaaaaaga aaaagaanat gccaaagctt cgctttgcca gtanaatccg    840

gaaaattcgg aaaaaagcaa ttttaaaana ttcttaatan gncatcttgn tttggcnttt    900

atggcctnat ttgcccttta agggttgnaa cngaaaaata annatgaaag cntgaagnaa    960

aacnaantnt ttggggnatt tntttcnccc agttttttta ttaataacaa gncncntttt   1020

taaaaaaatt tggnaatttt ttttaaanan aaaanaacct gctantcaaa atgngaaanc   1080

nanccatttt taaattnngg ttcnanntnt tttgggaaaa ntaaatttnt t            1131


<210>  349
<211>  1179
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (883)..(883)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (915)..(915)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (944)..(944)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (946)..(946)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (950)..(950)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (967)..(967)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (975)..(975)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1000)..(1000)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1012)..(1012)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1032)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1037)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1051)..(1051)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1054)..(1055)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1058)..(1058)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1067)..(1067)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1079)..(1079)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1093)..(1093)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1102)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1133)..(1133)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1158)..(1158)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1160)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1162)..(1162)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1166)..(1166)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1170)..(1170)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1176)..(1176)
<223>  n is a, c, g, or t

<400>  349
naaaagagaa attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cggcctgagc ctgagcctga gcccgagccg    120

ggagccggtc gcgggggctc cgggctgtgg gaccgctggg cccccagcga tggcgaccct    180

gtggggaggc cttcttcggc ttggctcctt gctcagcctg tcgtgcctgg cgctttccgt    240

gctgctgctg gcgcagctgt cagacgccgc caagaatttc gaggatgtca gatgtaaatg    300

tatctgccct ccctataaag aaaattctgg gcatatttat aataagaaca tatctcagaa    360

agattgtgat tgccttcatg tcgtggagcc catgcctgtg cgggggcctg atgtagaagc    420

atactgtcta cgctgtgaat gcaaatatga agaaagaagc tctgtcacaa tcaaggttac    480

cattataatt tatctctcca ttttgggcct tctacttctg tacatggtat atcttactct    540

ggttgagccc atactgaaga ggcgcctctt tggacatgca cagttgatac agagtgatga    600

tgatattggg gatcaccagc cttttgcaaa tgcacacgat gtgctagccc gctcccgcag    660

tcgagccaac gtgctgaaca aggtagaata tgcacagcag cgctggaagc ttcaagtcca    720

agagcagcga aagtctgtct ttgaccggca tgttgtcctc agctaattgg gaattgaatt    780

caaggtgact agaaagaaac aggcagacaa ctggaaagaa ctgactgggt tttgctgggt    840

ttcattttaa taccttgttg atttcaccaa ctgttgctgg aanaatcaaa actggaagca    900

aaaaacttgc ttganttttt ttttcttgtt aacgtaataa aaananaaan tttttaaaag    960

cccacanctc aaagncagcc caaaaanncc ttttccctan tttgggactt tnacnaaaaa   1020

aaaaaaaaat cntgccnnnn aaattatctt ngannccntt tacctgnaaa aagcccctnc   1080

tttttttccc ccnaaaattt tnancttgac tttcaaaaaa aattttccgg ggnttttggg   1140

ggggggtggt tttttggntn gnttgntttn gggggnaaa                          1179


<210>  350
<211>  1007
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (788)..(788)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (800)..(800)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (832)..(832)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (839)..(839)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (854)..(854)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (856)..(856)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (875)..(875)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (877)..(877)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (880)..(880)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (885)..(885)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (888)..(888)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (891)..(891)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (896)..(896)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (902)..(902)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (905)..(906)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (908)..(908)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (920)..(920)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (930)..(930)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (942)..(943)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (953)..(953)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (957)..(957)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (960)..(960)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (963)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (981)..(981)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (990)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (998)..(998)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1000)..(1000)
<223>  n is a, c, g, or t

<400>  350
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc ccacgcgtcc gtagggaagc agcagacaga    120

tgaggacgtc cggaagatgt ttgagccctt cgggaccatc gacgagtgca ctgtgctccg    180

ggggccagat ggcaccagca aaggctgcgc cttcgtgaag ttccagaccc acgctgaggc    240

ccaggcggcc atcaacaccc ttcacagcag ccggaccctg ccaggtgcct cgtccagcct    300

ggtggtgaag tttgctgaca ctgagaagga gcgaggtctc cgccgcatgc agcaggtggc    360

cacccagttg ggcatgttca gccccatcgc cctccagttt ggagcctaca gcgcctacac    420

ccaggccctg atgcagcagc aggcggccct ggtagcggct cacagtgcct acctcagccc    480

catggccacc atggctgccg tgcagatgca gcacatggct gccatcaatg ccaatggcct    540

catcgccacc cccatcaccc catcctcagg aaccagcacc cctcctgcca tcgctgccac    600

gcctgtctct gccattccgg ctgccctggg cgtcaacggc tacagcccgg tgcccaccca    660

gcccactggg cagcctgccc ctgatgctct gtatcccaac ggggttcacc cctacccagc    720

ccagagcccc gcggcccccg tggaccccct gcagcaggcc tacgcgggga tgcagcacta    780

cacagcancc tacccagcan cctacagcct ggttgcacct gcgttcccgc ancctccanc    840

cctggtcgcc caanancccc caccaccacc tcaanancan cacancanca ncacancaac    900

ancannanca caaaaaaaan gcctgatggn tgcaaatctt tnnttacact tgnccangan    960

ttnntgaatc aaaatcctcc naagtttgtn ccctttgncn cgtcatt                 1007


<210>  351
<211>  615
<212>  DNA
<213>  Homo sapiens

<400>  351
tagagaaatt aactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg cccacgcgtc cggtctttgt gtgtgtatgt    120

gtgatctctg cctgcaggac cagcccggtg gcaccctgga tctgaccctg atccgtgccc    180

gcctccagga gaagttgtca cctccctaca gctccccaca ggagtttgcc caggatgtgg    240

gccgcatgtt caagcaattc aacaagttaa ctgaggacaa ggcagacgtg cagtccatca    300

tcggcctgca gcgcttcttc gagacgcgca tgaacgaggc cttcggtgac accaagttct    360

ctgctgtgct ggtggagccc ccgccgatga gcctgcctgg tgctggcctg agttcccagg    420

agctgtctgg tggccctggt gatggcccct gaggctggag cccccatggc cagcccagcc    480

tggctctgtt ctctgtcctg tcaccccatc cccactcccc tggtggcctg actcccactc    540

cctggtggcc ccatccccca gttcctcacg atatggtttt tacttctgtg gatttaataa    600

aaacttcacc agttc                                                     615


<210>  352
<211>  716
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (383)..(383)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (426)..(426)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (437)..(437)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (458)..(458)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (466)..(466)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (470)..(470)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (501)..(501)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (529)..(529)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (541)..(541)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (547)..(547)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (565)..(565)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (571)..(571)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (577)..(577)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (584)..(584)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (588)..(588)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (591)..(591)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (594)..(595)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (598)..(598)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (600)..(600)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (611)..(611)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (622)..(622)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (624)..(624)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (626)..(626)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (639)..(639)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (652)..(652)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (660)..(660)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (663)..(663)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (665)..(665)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (668)..(668)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (685)..(685)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (689)..(689)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (699)..(699)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (702)..(702)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (709)..(709)
<223>  n is a, c, g, or t

<400>  352
antagagaga attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cgcccacgcg tccgctagtc caagtgtccg    120

gcaaacttgg atccatgaaa tcaaccaaat tttagaaaac cagcgcaatt ttttaaatgc    180

cttgacatcg ccaatcgagt accagaggaa ccacagcggg ggcggcggcg gcggcggcag    240

cgggggcagc ggcgggggtg ggggcagcgg cggcggcggg gcccccagtg gcggcagcgg    300

ccacagtggc ggccccagca gctgcggcgg cgcccccagc acgagcagga gccggccctc    360

ccggatcccc cagcctgtcc ganaccaccc ccccgtgctg gtctcctctg cagcctcgag    420

ccaggnagag gcagatnaga tgtcagagtg aaagcaanag cagtancaan atctccacca    480

tgttggtgac acacgattac ncggccagtg aaggaggatg atatcaacnt ctaccaagga    540

naggtcnttc aaattctggc cagcnaacca ncataanatg tttntggngt ntcnnagncn    600

ccactgacca ntgccccgca antnanggct ggattccang ctttgtcctg gnccaaccan    660

tgnantcntc gtgaagaacc cgganttgna ctcttcagna antccactnt cttggc        716


<210>  353
<211>  816
<212>  DNA
<213>  Homo sapiens

<400>  353
agaggatcgc atcaccatca ccatcacgga tcctatttag gtgacactat agaatcgtcg     60

acccacgcgt ccgatgagac ctattgcatt gacaacgagg ccctctatga tatctgcttc    120

cgcactctga agctgaccac accaacctac ggggatctga accaccttgt ctcagccacc    180

atgagtggtg tcaccacctg cctccgtttc cctggccagc tcaatgctga cctccgcaag    240

ttggcagtca acatggtccc cttcccacgt ctccatttct ttatgcctgg ctttgcccct    300

ctcaccagcc gtggaagcca gcagtatcga gctctcacag tgccggaact cacccagcag    360

gtcttcgatg ccaagaacat gatggctgcc tgtgaccccc gccacggccg atacctcacc    420

gtggctgctg tcttccgtgg tcggatgtcc atgaaggagg tcgatgagca gatgcttaac    480

gtgcagaaca agaacagcag ctactttgtg gaatggatcc ccaacaatgt caagacagcc    540

gtctgtgaca tcccacctcg tggcctcaag atggcagtca ccttcattgg caatagcaca    600

gccatccagg agctcttcaa gcgcatctcg gagcagttca ctgccatgtt ccgccggaag    660

gccttcctcc actggtacac aggcgagggc atggacgaga tggagttcac cgaggctgag    720

agcaacatga acgacctcgt ctctgagtat cagcagtacc aggatgccac cgcagaagag    780

gaggaggatt tcggtgagga ggccgaagag gaggcc                              816


<210>  354
<211>  866
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  n is a, c, g, or t

<400>  354
aatngagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gctggcggtg aacatggtgc ccttccctcg    120

cctgcacttc ttcatgcccg gcttcgcgcc cctgaccagc cggggcagcc agcagtaccg    180

ggcgctcacg gtgcccgagc tcacccagca gatgttcgac tccaagaaca tgatggccgc    240

ctgcgacccg cgccacggcc gctacctgac ggtggctgcc atcttccggg gccgcatgtc    300

catgaaggag gtggacgagc agatgctcaa cgtgcagaac aagaacagca gctacttcgt    360

ggagtggatc cccaacaacg tgaagacggc cgtgtgcgac atcccgcccc gcggcctgaa    420

gatgtcggcc accttcatcg gcaacagcac ggccatccag gagctgttca agcgcatctc    480

cgagcagttc acggccatgt tccggcgcaa ggccttcctg cactggtaca cgggcgaggg    540

catggacgag atggagttca ccgaggccga gagcaacatg aacgacctgg tgtccgagta    600

ccagcagtac caggacgcca cggccgacga acaaggggag ttcgaggagg aggagggcga    660

ggacgaggct taaaaacttc tcagatcaat cgtgcatcct tagtgaactt ctgttgtcct    720

caagcatggt ctttctactt gtaaactatg gtgctcagtt ttgcctctgt tagaaattca    780

cactgttgat gtaatgatgt ggaactcctc taaaaattac agtattgtct gtgaaggtat    840

ctatactaat aaaaaagcat gtgtag                                         866


<210>  355
<211>  1227
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (902)..(902)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (971)..(971)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (995)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1023)..(1023)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1027)..(1027)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1030)..(1030)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1033)..(1034)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1047)..(1047)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1050)..(1050)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1063)..(1063)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1069)..(1069)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1073)..(1073)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1078)..(1078)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1092)..(1093)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1149)..(1149)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1151)..(1151)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1172)..(1172)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1178)..(1178)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1180)..(1180)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1186)..(1186)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1193)..(1196)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1208)..(1208)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1216)..(1216)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1219)..(1219)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1222)..(1222)
<223>  n is a, c, g, or t

<400>  355
tagaggaaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc ggtcaaatcc tggaaacagt ctacaaacac    120

agctgtgggg ggttgcctcc tgttcgaagt gcactggaaa aaatcctggc cgtttgtcat    180

ggggtcatgt ataaacagct ctcagcctgg atgctccatg gactcctctt ggaccagcat    240

gaagaattct ttatcaaaca ggggccatct tctggtaatg tcagtgccca gccagaagag    300

gacgaggagg acctgggcat tgggggactg acaggaaaac aactgagaga actgcaggac    360

ttgcgcctga ttgaggaaga gaacatgctg gcaccatctc tgaagcagtt ttccctacga    420

gtggagattt tgccatccta cattccagtg agggttgctg aaaaaatcct atttgttgga    480

gaatctgtcc agatgtttga gaatcaaaat gtgaacctga ctagaaaagg atccattttg    540

aaaaaccagg aagacacttt tgctgcagag ctgcaccgtc tcaagcagca gccactcttc    600

agcttggtgg actttgaaca ggtggtggat cgcattcgca gcactgtggc tgagcatctc    660

tggaagttga tggtagaaga atccgattta ctgggtcagc tgaagatcat taaagacttt    720

taccttctgg gacgtggaga actgtttcag gccttcattg acacagctca acacatgttg    780

aaaacaccac ccactgcagt aactgagcat gatgtgaatg tggcctttca acagtcagca    840

cacaaggtat tgctagatga tgacaacctt ctccctctgt tgcacttgac aatcgagtat    900

cncggaaagg agcacaaaga tgctactcag gcaagagaag ggccttctcg ggaaacttct    960

cccccgggaa nccctgcatc tggctgggca gcccntaggt ttttccctac aaaagtaagn   1020

ggncccntan aannttctct tcccccnacn tgtcctggaa aantacaang ttnttttnaa   1080

atacttactg anngggcccc gggngcaaac ttaacttgca cccttgctgg gccctaaaat   1140

ggcgggcang nccctcagtc aaaccaaatg gngattcnan gggccnaaaa aannnnggat   1200

tttggggnaa acctcnaana tncccgg                                       1227


<210>  356
<211>  875
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (856)..(856)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (863)..(864)
<223>  n is a, c, g, or t

<400>  356
gagatactat gagaggtcgc atcccatcac catcacggat cctatttagg tgacactata     60

gaatcgtcga ctctggacct tggctgtcac tcagttaaga aggcgaatgc aatgctggac    120

gaggacgagg atgagcgtgt ggacgaggct gccctgcggc agctcacggg gatgggcttt    180

ccggagaaca gagccaccaa ggcccttcag ctgaaccaca tgtcggtgcc tcaggccatg    240

gagtggctaa ttgaacacgc agaagacccg accatagaca cgcctcttcc tggccaagct    300

cccccagagg ccgagggggc cacagcagct gcctccgagg ctgccgcggg agccagcgcc    360

accgatgagg aggccagaga tgagctgacg gaaatcttca agaagatccg gaggaaaagg    420

gagtttcggg ctgatgctcg ggccgtcatt tccctgatgg agatggggtt cgacgagaaa    480

gaggtgatag atgccctcag agtgaacaac aaccagcaga atgccgcgtg cgagtggctg    540

ctgggggacc ggaagccctc tccggaggag ctggacaagg gcatcgaccc cgacagtcct    600

ctctttcagg ccatcctgga taacccggtg gtgcagctgg gcctgaccaa cccaaaaaca    660

ttgctagcat ttgaagacat gctggagaac ccactgaaca gcacccagtg gatgaatgat    720

ccagaaacgg ggcctgtcat gctgcagatc tctagaatct tccagacact aaatcgcacg    780

taggtggcgt cgttccactc ggctatcagg ccacagcagc cccctggtgc ggcccgagac    840

cgggcagagt ggaccntcac tgnnaaactc acttc                               875


<210>  357
<211>  553
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (261)..(261)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (276)..(276)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (286)..(286)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (289)..(289)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (302)..(302)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (314)..(314)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (316)..(316)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (327)..(327)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (332)..(332)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (338)..(338)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (356)..(356)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (370)..(370)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (372)..(372)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (381)..(381)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (383)..(383)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (386)..(386)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (388)..(388)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (407)..(407)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (428)..(428)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (432)..(432)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (435)..(435)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (442)..(442)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (464)..(464)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (471)..(471)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (491)..(493)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (495)..(496)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (499)..(499)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (504)..(504)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (508)..(509)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (512)..(512)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (526)..(527)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (529)..(529)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (537)..(537)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (547)..(547)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (549)..(549)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (552)..(552)
<223>  n is a, c, g, or t

<400>  357
taagaggaga attaactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgcccacgc gtccgcccac gcgtccgagc    120

agaggttgat ctttgccgga aaacagctgg aagatggtcg caccctgtct gactacaaca    180

tccagaaaga gtccaccttg cacctggtgc tccgtctcag aggtgggatg cagatcttcg    240

tgaagaccct gactggtaaa ncatcactct cgaggnggag ccgagnganc cattgagaat    300

gncagggcaa agancnaaaa aaggganggc tnccctcnga acaacaaaag ttgttntttt    360

gtgggaaaan cntggaaaaa ngngcncncc ctttttggtt taaaaanttc caaaaaaagg    420

cccccccngc cnccnggggg gncccctttt aaaggggggg gagnaaaatt nttttttgga    480

aaaacccttt nnngnngana aaancccnnc cncctcaggg gggggnncng gggggcnccc    540

ctttttngna ang                                                       553


<210>  358
<211>  948
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (4)..(12)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (16)..(16)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (21)..(21)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (23)..(23)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (30)..(30)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (41)..(41)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (45)..(45)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (59)..(59)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (62)..(62)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (383)..(383)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (587)..(587)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (750)..(750)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (822)..(822)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (847)..(848)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (866)..(866)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (876)..(877)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (887)..(887)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (891)..(891)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (896)..(896)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (912)..(912)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (917)..(917)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (925)..(925)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (930)..(930)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (932)..(932)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (936)..(936)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (942)..(942)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (944)..(944)
<223>  n is a, c, g, or t

<400>  358
tntnnnnnnn nncctnctcg ngnattatcn tatgtagagg ntcgnatcac catcaccant     60

cncgggatcc tatttaggtg acactataga atcgtcgacc cacgcgtccg ccggaccgca    120

tctcccccca cgggggtcgg tgcctgggga tcctgtccgc atccactgca acatctggtc    180

ggtggagtct gatgacccta acttggctgc tgtcttggag aggctggtgg acataaagaa    240

agggaatact ctgctattgc agcatctgaa gaggatcatc tccgacctgt gtaaactcta    300

taacctccct cagcatccag atgtggagat gctggatcaa cccttgccag cagagcagtg    360

cacacaggaa gacgtgtctt canaagatga agatgaggag atgcctgagg acacagaaga    420

cttagatcac tatgaaatga aagaggaaga gccagctgag ggcaagaaat ctgaagatga    480

tggcattgga aaagaaaact tggccatcct agagaaaatt aaaaagaacc agaggcaaga    540

ttacttaaat ggtgcagtgt ctggctcggt gcaggccact gaccggntga tgaaggagct    600

cagggatata taccgatcac agagtttcaa aggcggaaac tatgcagtcg aactcgtgaa    660

tgacagtctg tatgattgga atgtcaaact cctcaaagtt gaccaggaca gcgctttgca    720

caacgatctc cagatcctca aagagaaaan aaggagccga ctttcattct actttaactt    780

ttcctttaaa gaaaactttt cccttttgac ccaccatttg tncaggggtt tgtgtctcca    840

gtccctnntc tggaggggta tgtttnttgg ggcggnnggg ccccatnctg ncatgnaaaa    900

ctttctcacc cnaaaanagg ggctnggaan cnaagngccc tncntccc                 948


<210>  359
<211>  984
<212>  DNA
<213>  Homo sapiens

<400>  359
ctatgagagg atcgcatcac catcaccatc acggatccta tttaggtgac actatagaat     60

cgtcgaccca cgcgtccgga gatgaaaaag aattggacaa aagagaaaaa gccaagaaat    120

tggacaaaga gaatctcagt gatgaaagag ccagtgggca aagttgtaca ttgcccaagc    180

gttctgatag cgaacttaaa gatgaaaaac caaagagacc tgaagatgag agcggcagag    240

actataggga gagggaacgg gaatatgaac gagatcagga gcgcatactt cgagaaagag    300

agaggctgaa gcggcaagaa gaagagcgcc gtaggcagaa ggagcgctat gagaaagaga    360

agacttttaa gagaaaagaa gaagaaatga aaaaagagaa agacacactt cgggataaag    420

gaaagaaggc tgaaagtaca gaatcaatag gcagctcaga aaaaactgaa aagaaagaag    480

aagtggtcaa gagagatcga ataagaaaca aggatcgtcc agcgatgcag ctttaccaac    540

caggagctcg aagccgaaat cgactctgtc cccctgatga cagcaccaag tctggagatt    600

cagcagcaga aaggaagcag gaaagtggta ttagccatag aaaagaagga ggagaggagt    660

gataagtcca gatggcctta ggtgtcctga ctgtctaggc agccaaagag cacacgttaa    720

gcaatccaga ggtgccttca gggcaaagaa tagagagaaa gggagccgct gtgctggtgg    780

ggtacactgc agaggagtaa gtcttgtgtc aaagcaggaa tctgatcaga ggttcagaat    840

tggaagtaca atttcattgc ttttgcaatt tctacaaatt aattttaaag tgtcagaaaa    900

aggtgacggc aaggacatgc attgcaattt gcagggggaa ttgtcaagtg aggacttcat    960

cacatatgac acgagagaaa gtaa                                           984


<210>  360
<211>  874
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (710)..(710)
<223>  n is a, c, g, or t

<400>  360
agagattact atgagaggtc gcatcccatc accatcacgg atcctattta ggtgacacta     60

tagaatcgtc gactctggac cttggctgtc actcagttga ttcgagtgct ccggcgcaca    120

gacccgcgcc ccgccgtccg cgagcctccc gagagccgtc ccttcgtccg gccctggagc    180

attgcgtttg tcgccggtgt cgcagtgcga ggatggcgcc gcgggtgtag cggctctctg    240

cgcaggccga gtgggcccag agaagcgagg aactccgcag ctcgtcgaca cgtctcgtct    300

cctgtcccaa ttcagggctt ggtgaggtga ctcgcggtcg cgggtgactc gccggcagga    360

cactgcctgg aacgcctgga gcgcctccca ctgcagacgt ctgtccgcct ccagccgctc    420

tcctctgacg ggtcctgcct cagttggcgg aatggcggcc acgggagcca atgcagagaa    480

agctgaaagt cacaagtctg gagcccggca ctgtggtcat aacagagcat gcagtggata    540

cctgcttcaa ggcagagttt gagcagattg tcctggggaa gcgggtcatc cggaaaacgg    600

accttaacaa gaagctggtg caggagctgt tgctgtgttc tgcagagctg agcgagttca    660

ccacagtggt ggggaacacc atgtgcacct tggacttcta tgaaaggcan ggccgtctgg    720

atggggctct ctgctcctac acggagaaag gacagcaggc gtatctggag gcagcctatg    780

cagccggcgt ccgcaatatc gagatggagt cctcggtgtt tgccgccatg tgcagcgcct    840

gcggcctcca gcggccgtgt gtgtgtcacc tcct                                874


<210>  361
<211>  1314
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (617)..(617)
<223>  n is a, c, g, or t

<400>  361
ncatataatg acttacctat aaaataggcg tatcacgagg ccctttcgtc ttcacctcga     60

gaaatcataa aaaatttatt tgctttgtga gcggataaca attataatag attcaattgt    120

gagcggataa caatttcaca cagaattcat taaagaggag aaattaacta tgagaggatc    180

gcatcaccat caccatcacg gtcgacccac gcgtccgccc acgcgtccgg gggacctgat    240

gttcctgctg gacagctcag ccagcgtctc tcactacgag ttctcccggg ttcgggagtt    300

tgtggggcag ctggtggctc cactgcccct gggcaccggg gccctgcgtg ccagtctggt    360

gcacgtgggc agtcggccat acaccgagtt ccccttcggc cagcacagct cgggtgaggc    420

tgcccaggat gcggtgcgtg cttctgccca gcgcatgggt gacacccaca ctggcctggc    480

gctggtctat gccaaggaac agctgtttgc tgaagcatca ggtgcccggc caggggtgcc    540

caaagtgctg gtgtgggtga cagatggcgg ctccagcgac cctgtgggcc cccccatgca    600

ggagctcaag gacctgngcg tcaccgtgtt cattgtcagc accggccgag gcaacttcct    660

ggagctgtca gccgctgcct cagcccctgc cgagaagcac ctgcactttg tggacgtgca    720

tgacctgcac cttcattgtc caagaactga aggggtccat ctccacgcaa tgcggccgca    780

ccagctccat gccacggaga atcagttcca gggctttcgc ctgggctggc ccacccctgc    840

tgaacgcaaa atccggctaa ctatgtggtg gagattgtgc cccaccctca tccctggggg    900

tcataaaacg cccaatctcc ctcggaaccc acagaacgga atttcgacac ccccatcccc    960

cttcttcaaa ttacacttcg gctactggcc aagaacaaaa gctccctacc taaagcctca   1020

aacacaccca cgactaatac aaatccatta tcaccataat caaccactct actatacctc   1080

atcccaatgt gataacctac cccttttcta cttactcact tacatctcaa atacattctc   1140

acaccactat aagtaaccaa cccactatca aactcaaaac cacaagaacc caacttatat   1200

aatattccta ctcatcacac actcatctca aaacaacaac atctcgacaa ccaatgcaaa   1260

tcaacaaagg tcaatcacta aatgccagct tccactcact atatcaaacc tcct         1314


<210>  362
<211>  1167
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (842)..(842)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (980)..(980)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (983)..(983)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1013)..(1013)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1022)..(1022)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1036)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1039)..(1039)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1046)..(1046)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1050)..(1050)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1053)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1057)..(1058)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1064)..(1064)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1072)..(1072)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1076)..(1076)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1082)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1086)..(1086)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1090)..(1090)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1099)..(1099)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1102)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1116)..(1116)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1136)..(1136)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1146)..(1146)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1156)..(1157)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1160)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1164)..(1164)
<223>  n is a, c, g, or t

<400>  362
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc ggtctttcta tggagcatga ggtcctacac    120

gttaattcgg aagctagagg gccatcaaag cagtgttgtc tcttgtgact tctcccccga    180

ctctgccctg cttgtcacgg cttcttacga taccaatgtg attatgtggg acccctacac    240

cggcgaaagg ctgaggtcac tccaccacac ccaggttgac cccgccatgg atgacagtga    300

cgtccacatt agctcactga gatctgtgtg cttctctcca gaaggcttgt accttgccac    360

ggtggcagat gacagactcc tcaggatctg ggccctggaa ctgaaaactc ccattgcatt    420

tgctcctatg accaatgggc tttgctgcac attttttcca catggtggag tcattgccac    480

agggacaaga gatggccacg tccagttctg gacagctcct agggtcctgt cctcactgaa    540

gcacttatgc cggaaagccc ttcgaagttt cctaacaact taccaagtcc tagcactgcc    600

aatccccaag aaaatgaaag agttcctcac atacaggact ttttaagcaa caccacatct    660

tgtgcttctt tgtagcaggg taaatcgtcc tgtcaaaggg agttgctgga ataatgggcc    720

aaacatctgg tcttgcattg aaatagcatt tctttgggat tgtgaataga atgtagcaaa    780

accagattcc agtgtactag tcatggatct ttctctccct ggcatgtgaa agtcagtctt    840

anaggaagag attccacttg cacggcaaca gagccttacg ttaaaatttt cagtccagtt    900

atgaacagca agtgttgaac tctttctgct tgttttgatt caaagtgcag ttactgatgt    960

tgttttgata tgcaactaan tangcctcca aagcctctct agtggcaaaa canctcaaac   1020

tncccccgct gggaangang gcttcngccn aanaccnncc ttgngttctg angcanggga   1080

ancatnggtn caagttccnc cngctggggn caaaantgct ccaaggtggc caaggntttt   1140

tttttngggc tccttnngan ctgnagg                                       1167


<210>  363
<211>  1032
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (828)..(828)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (863)..(863)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (906)..(907)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (916)..(917)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (944)..(944)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (946)..(946)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (951)..(951)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (955)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (962)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (980)..(983)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (993)..(993)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1003)..(1003)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1017)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1027)..(1027)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1030)..(1030)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1032)..(1032)
<223>  n is a, c, g, or t

<400>  363
gattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag gtgacactat     60

agaatcgtcg acccacgcgt ccggtgaaat taaaaaaaca gtagttttgc cacccattgt    120

tgccagcaga ggacaatcag aggagcctgc aggtaaaaca aagtctatgc aggaggtgca    180

catcaagacg ctggaagaaa ttaaactgga gaaggcactg agggtgcagc agagctctga    240

gagcagcacc agctccccgt ctcaacacga ggccactcca ggggcaaggc ggctgctgcg    300

aatcaccaaa agaacaggga tgaaagaaga gaagaacctt caggaaggaa atgaagttga    360

ttctcagagc agtattagaa cagaagctaa agaggcttca ggtgagacca caggagttga    420

catcactaaa attcaagtca agagatgtga gaccatgaga gagaagcaca tgcagaaaca    480

gcaggagagg gaaaaatcag tcttgacacc tcttcgggga gatgtagcct cttgcaatac    540

ccaagtggca gagaaaccag tgctcactgc tgtgccagga atcacacggc acctgaccaa    600

gcggcttccc acaaagtcat cccagaaggt ggaggtagaa acctcaggga ttggagactc    660

attattgaat gtgaaatgtg cagcacagac cttggaaaaa aggggtaaag ctaaacccaa    720

agtgaacgtg aagccatctg tggttaaagt tgtgtcatcc cccaaattgg ccccaaaaac    780

gtaaggcagt ggaagatgca cgctgctgtc attgccgctg tgaagccnct cagctccagc    840

agtgtcctac aggaaccccc cancccaaaa aggcagctgt ggctgtttgt cccgcttgtc    900

tctgannaac aaatcnntcc cctgtgcctg aaaccaaaaa aatncnaaaa naacnntctt    960

tntggctgcc tcccaacccn nnnccttctt tcnaattcct ccnccccccg ggaaggnntn   1020

tgggccnttn cn                                                       1032


<210>  364
<211>  879
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (733)..(733)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (761)..(761)
<223>  n is a, c, g, or t

<400>  364
agatactatg agaggtcgca tcaccatcac catcacggat cctatttagg tgaactatag     60

aatcgtcgac tctggacctt ggctgtcact cagttagtgt aaaaggagat aagtgtaagt    120

tctcccatga cttgactctg gagagaaaat gtgaaaagcg aagtgtttac attgatgcaa    180

gagatgaaga acttgaaaaa gatactatgg ataattggga tgagaaaaag ctggaagaag    240

tagtgaacaa gaagcacggt gaggcggaaa agaaaaaacc aaaaactcaa atagtgtgca    300

ggcatttcct ggaagctatt gaaaacaaca agtatggctg gttttgggta tgccctggag    360

ggggtgatat ttgcatgtat cgtcatgcac ttcctcctgg atttgtgttg aaaaaagata    420

aaaagaaaga agagaaagaa gatgaaattt cattagaaga tctaattgag agagagcgtt    480

ctgccctagg tccaaatgtt accaaaatca ctctagaatc ttttcttgcc tggaagaaaa    540

ggaaaagaca agaaaagatt gataaacttg aacaagatat ggaaagaagg aaagctgact    600

tcaaagcagg gaaagcacta gtgatcagtg gtcgtgaagt gtttgaattt cgtcctgaac    660

tggtcaatga tgatgatgag gaagcagatg atacccgcta cacccaggga acaggtggtg    720

atgaagttga tgnatcagtg agtgtaaatg acatagattt nagcctgtac atcccaagag    780

atgtagatga aacaggtatt actgtagcca gtctttgaag atcagcacat atacttcgaa    840

taagatgaaa caattaagtg agcttctgga gtaggctga                           879


<210>  365
<211>  1172
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (19)..(19)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (892)..(892)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (904)..(904)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (929)..(929)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (974)..(974)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (985)..(985)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (994)..(994)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (998)..(998)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1003)..(1003)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1010)..(1010)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1022)..(1022)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1027)..(1027)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1037)..(1037)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1045)..(1045)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1048)..(1048)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1051)..(1051)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1060)..(1060)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1062)..(1062)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1075)..(1075)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1083)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1085)..(1085)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1089)..(1089)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1095)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1103)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1108)..(1109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1121)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1135)..(1136)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1144)..(1144)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1152)..(1152)
<223>  n is a, c, g, or t

<400>  365
gnnatataga gagaattanc tatggagagg atcgcatcac catcaccatc acggatccta     60

tttaggtgac actatagaat cgtcgaccca cgcgtccgcc cacgcgtccg ctgacacgca    120

cgactccccc cgcggcaact gcacaggttc aggtgaggct attgggaaaa tgcagcaaca    180

gggaattcct ggaggaattt tcttccactg tgagagattt gatcaaccca taggagaaga    240

ttcattatgt tctattttag aagaactgtg gcaagataat gaccagctag agcaacgtca    300

ggaaaaccag aataaccttt taagtcatgt gaaagtattg attaaggaga ggggctatga    360

acataaaaac attgaaaaaa taattcatgt gactaccaag cttgttcctt caattaaaag    420

actccataac tgtgacacaa ttttgaagca tactttaaac tcacataatc ataatagaaa    480

cagtgcaaca aagaaccttg gcaagatttt tggaaatggt aacaatttcc cccatagccc    540

ttcctctact aagaatgaga atgctaaaac aggagcaaat tcctgtgaac atgaccacta    600

tgaaaaacat ctcagccaca aacaagctcc cacccaccat cagaaaattc atcctgagga    660

gaagctttat gtgtgtactg aatgtgtaat gggcttcact cagaagtcac atctgtttga    720

gcatcagaga attcatgctg gagaaaagtc ccgtgaatgt gacaaaagca acaaagtctt    780

cccccagaaa ccccaggttg atgtacatcc aagtgtttat acagggagaa aaaccctatc    840

tgtgtactca atgtgggaaa gtctttaccc ctcaaatcaa accttcatta cncatcaaaa    900

aaantcatta ccgggcaaaa aaccctaana aaatgccagt ggaatgtgga aaaacctttt    960

ttcccaaaaa tcanaacctc ttttnaaacc ttcngganaa ttncataccn gggaaaaaaa   1020

anccttnaga aattgcncgn ggaanggngg naaaaaggcn tnctccccaa aactncaacc   1080

cnntngtant ccttnnaaaa acnncctnnc cggaaaaaaa nccctttgaa ttccnntgaa   1140

tggngggaag gnctttcccc aaaaaaatct cc                                 1172


<210>  366
<211>  1211
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (796)..(796)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (803)..(803)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (931)..(931)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (949)..(949)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (958)..(958)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (964)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (969)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (974)..(974)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (981)..(981)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (994)..(994)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1000)..(1000)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1004)..(1004)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1019)..(1019)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1023)..(1024)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1048)..(1048)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1069)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1080)..(1080)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1086)..(1086)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1089)..(1089)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1103)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1112)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1120)..(1121)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1123)..(1123)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1126)..(1126)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1130)..(1130)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1143)..(1143)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1146)..(1146)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1151)..(1151)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1156)..(1156)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1162)..(1163)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1168)..(1168)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1176)..(1176)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1181)..(1181)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1184)..(1184)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1192)..(1192)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1200)..(1200)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1202)..(1202)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1211)..(1211)
<223>  n is a, c, g, or t

<400>  366
tagaggnaat tactatggag aggatcgcat caccatcacc atcacgggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cgctcttact gaacataaga taattcatac    120

tggagagaaa ccctacaaat gtgaagaatg tggcaaagca tttagccaat cctcaaccct    180

aactagacat acgaggatgc acactggaga gaaaccatac aaatgtgaag aatgtggcaa    240

agcttttaat cgatcctcaa agcttactac acataagata attcatactg gagagaaacc    300

ttacaagtgt gaagaatgtg gcaaagcatt tatatcatcc tcaaccctaa atggacataa    360

gagaattcat actagagaga aaccctacaa atgtgaagaa tgtggcaaag catttagcca    420

atcttcaacc ctaactagac ataagaggtt gcacaccgga gagaaaccct acaaatgtgg    480

agaatgtggc aaagccttta aagagtcctc agctcttact aaacataaga taattcacac    540

tggagagaaa ccctacaaat gtgaaaaatg tggcaaagcc tttaaccagt cttcaatcct    600

tactaaccat aagaaaattc atactatcac acctgtaatc ccagcacttt gggaggccga    660

ggcgggcgga tcacgaggtc aggagatgga gaccatcctg gctaacacag tgaaacccct    720

tctctactaa aaaatacaaa aaattagccg ggcgtggtgg cgggcgcctg tagtcccagc    780

tatgcgagag gctgangcag ganaatggcg tgaacccggg aggcggagct tgcagtgagc    840

cgagatcacg ccactgcact caagcctggg cgacagagcg agactccgtc tcaaaaaaaa    900

aaaaaagaaa attcctacta gagagaaccc ntacaaatat aaagaatgng gcaaatcntt    960

ttancgggnc ttcnaccttt nctnaacata aggnaattcn tacnggaatt aaactctana   1020

atnnggaaaa agggggcaan cctttttncg ggcccccccc ctacccgann taaaaaaatn   1080

cttccnggnc agcaccctac aanngggaaa anttggcaan ncnttnaccn gttttccccc   1140

ttnctncgaa naaaanaccc cnntgggnaa aaaacnttaa nggngggaaa angggggaan   1200

gncttaaaaa n                                                        1211


<210>  367
<211>  837
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (723)..(724)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (761)..(762)
<223>  n is a, c, g, or t

<400>  367
aggtcgcatc accatcacca tcacggatcc tatttaggtg acactataga atcgtcgact     60

ctggaccttg gctgtcactc agttaggaag cccgggactg tgagcttcgc ggacgtggcc    120

gtgtacttct ccccggagga gtggggctgt ctgcggcccg cgcagagggc tctgtaccgg    180

gacgtgatgc aggagaccta cggccacctg ggcgcgctcg gattcccagg ccccaaacca    240

gccctcatct cttggatgga acaggagagt gaggcttgga gccccgccgc ccaggatcct    300

gagaaggggg aaagactggg aggagctcgg agaggagatg tcccaaacag gaaggaagag    360

gaaccggagg aagtcccaag agccaaaggg cctagaaagg ctcctgtgaa ggagagtcct    420

gaagtgctgg tggaacgcaa ccctgaccca gctattagcg tggccccggc acgggcacag    480

ccacccaaaa atgctgcctg ggacccgacc acaggagcac agcccccggc acccataccc    540

agcatggatg ctcaggccgg ccagcggcgc cacgtgtgca cggactgcgg ccgctcccta    600

tagtgagtcg tattaagctt aattagctga gcttggactc ctgttgatag atccagtaat    660

gacctcagaa ctccatctgg atttgttcag aacgctcggt tgccgccggg cgttttttat    720

tgnntgagat ccagctagct tggcgagatt ttcagagcta nngagctaaa tggagaaaaa    780

tcactggaat acaccgtgat tatccatggc tcgtaagaca tttgagcatt cagtcgt       837


<210>  368
<211>  1169
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (871)..(871)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (936)..(936)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (954)..(954)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (990)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1002)..(1002)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1045)..(1045)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1061)..(1061)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1067)..(1067)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1069)..(1069)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1079)..(1079)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1082)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1084)..(1084)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1086)..(1086)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1091)..(1091)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1094)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1118)..(1118)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1127)..(1127)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1136)..(1136)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1158)..(1158)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1160)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1165)..(1165)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1168)..(1168)
<223>  n is a, c, g, or t

<400>  368
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccga gaaaatggcg gcaggggtcg aagcggcggc    120

ggaggtggcg gcgacggaga tcaaaatgga ggaagagagc ggcgcgcccg gcgtgccgag    180

cggcaacggg gctccgggcc ctaagggtga aggagaacga cctgctcaga atgagaagag    240

gaaggagaaa aacataaaaa gaggaggcaa tcgctttgag ccatatgcca atccaactaa    300

aagatacaga gccttcatta caaacatacc ttttgatgtg aaatggcagt cacttaaaga    360

cctggttaaa gaaaaagttg gtgaggtaac atacgtggag ctcttaatgg acgctgaagg    420

aaagtcaagg ggatgtgctg ttgttgaatt caagatggaa gagagcatga aaaaagctgc    480

ggaagtccta aacaagcata gtctgagcgg aagaccactg aaagtcaaag aagatcctga    540

tggtgaacat gccaggagag caatgcaaaa ggtgatggct acgactggtg ggatgggtat    600

gggaccaggt ggcccaggaa tgattactat cccacccagt atcctaaata atcccaacat    660

cccaaatgag attatccatg cattacaggc tggaagactt ggaagcacag tatttgtagc    720

aaatctggat tataaagttg gctggaagaa actgaaggaa gtatttagta tggctggtgt    780

ggtggtccga gcagacattc ttgaagataa agatggaaaa agtcgtggaa taggcactgt    840

tacttttgaa cagtccattg aagctgtgca ngctatatct atgttcatgg ccagctgcta    900

tttgatagac catgcacgtc aagatggatg agaggnctta ccaaaaggag attnctttcc    960

ctcctgagcg tccccacact tcccatggcn tggtggtatt gncatgggtt agacnggagg   1020

cacccttgag ccatccctga ataangcctc gaatggaact nggtccncng gatggaggnc   1080

cntngngggg ntgnaaantg gtcnattgat ttggaganct ggccganaat gaatcntata   1140

tgcctgaaaa agaaaatntn caacnggng                                     1169


<210>  369
<211>  949
<212>  DNA
<213>  Homo sapiens

<400>  369
ctatgagagg tcgcatcacc atcaccatca cggatcctat ttaggtgaca ctatagaatc     60

gtcgacccac gcgtccgcgg acgcgtgggt gacaactgaa gttgaaaaaa tcaagacgac    120

agtgaaggag tcagccacag aggagaagct gacccctgtg ttgctggcta aacagctggc    180

agccctgaag cagcagctgg ttgcttccca cctggagaag ctgctgggac cagatgctgc    240

aatcaacctt accgaccccg atggcgccct ggctaagcgc ctactactgc agctggaagc    300

aacaaagaac agcaaagggg gatcaggggg aaaaaccact gggacccccc cagatagcag    360

ccttgtcact tatgaactac attctcggcc tgagcaggac aagttctctc aagctgccaa    420

agtcgcagaa cttgaaaagc gcctgacaga gctggagaca gctgtacgtt gtgatcagga    480

tgctcagaat cccctttctg caggtctaca gggagcctgt ctcatggaga ctgtagagct    540

gttgcaagca aaggtgagcg ccctagacct tgcagttttg gatcaagtgg aggctcggct    600

acagagtgtc ctgggaaagg tgaacgagat tgccaagcat aaagcctctg tagaagatgc    660

agatacacaa agcaaggtgc accagctata tgaaactata cagcgctgga gccccattgc    720

ctccaccctc cctgagctgg tgcagagact tgtcaccatc aagcagctgc acgagcaagc    780

catgcagttt ggtcagctcc tgacacactt ggataccacc cagcagatga ttgctaattc    840

cttgaaggac aataccaccc tcttgaccca ggtgcagaca accatgcgtg aaaacctggc    900

cacagttgag gggaactttg ccagcattga tgaacggatg aagaagctg                949


<210>  370
<211>  1427
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  n is a, c, g, or t

<400>  370
nggcgccgcc tnccgggaga tactagagag gatgcatcac catcaccatc acggtcgacc     60

cacgcgtccg cgcttcgacg ggctgggctg tgcgcctgcg cagtgtgggt cgctcccgat    120

tccctgcccc ggccggcccc gcctcggctc cgcaccctcg ccccgctctc agccgccgct    180

ctgccccgca gcagccagcc ccgtgtccgg cagtatgttc agctgggtca gcaaggatgc    240

ccgccgcaag aaggagccgg agctcttcca gacggtggct gaggggctgc ggcagctgta    300

cgcgcagaag ctgctacccc tggaggagca ctaccgcttc cacgagttcc actcgcccgc    360

gctggaggac gctgacttcg acaacaagcc tatggtgctc ctcgtggggc agtacagcac    420

gggcaagacc accttcatcc gacacctgat cgtgcaggac ttcccgggga tgcgcatcgg    480

gcccgagccc accaccgact ccttcatcgc cgtcatgcac ggccccactg agggcgtggt    540

gccgggcaac gcgctcgtgg tggacccgcg gcgccccttc cgcaagctca acgcgtttgg    600

caacgctttc ctcaacaggt tcatgtgtgc ccagctgccc aaccccgtcc tggacagcat    660

cagcaatcat cgacaccccc gggatcctgt ctggagagaa gcatcggatc agcagaggct    720

atgactttgc cagccgcctg gagcggatcc cggaacgagc gaaccgcatc atcctgctct    780

tcgacgccca caagctggac atcaccgatg agaaccccga agaagataag gctcccaaaa    840

accatgaaga aaaaaaaacg ctcggggttt aaaaaagtga tccccaatag aaaccacacc    900

aattcaaata gaacaatgac ccccccatgt gaacccagcg caaagaccaa aataacaccc    960

atcttaatca ccacgattat ccaaaaacag taaccaccca attcaaacta accaaagtaa   1020

ccaaccttaa cgaatacact aataataaaa acaaaataaa aaacactgca taaaaccacc   1080

acacctcaaa taagacacaa caaaaattat aataatacca caatcaccac taatccaaac   1140

catctataca cacttaaaat acctacaata caccatccaa cacatcacca caacacaaaa   1200

gataccaaac ctaacaacaa acaagataat taaatcaata atcaaactca atcaagttaa   1260

acgtacctaa caacaatgta ctcaacatca ccacatccac cccctaaacc acaaaaccta   1320

ccaatacctc acctcatccc atagacccac acacaacaaa ataactgaga tatcgtataa   1380

ccatacatga acacatcaca caaaatatca ctctccctgt ctacact                 1427


<210>  371
<211>  489
<212>  DNA
<213>  Homo sapiens

<400>  371
atggctgtgc tgccggcact tctgcgcagc ggcgcccgca gccgcagccc cctgctccgg     60

aggctggtgc aggaaataag atatgtggaa cggagttatg tatcaaaacc cactttgaag    120

gaagtggtca tagtaagtgc tacaagaaca cccattggat cttttttagg cagcctttcc    180

ttgctgccag ccactaagct tggttccatt gcaattcagg gagccattga aaaggcaggg    240

attccaaaag aagaagtgaa agaagcatac atgggtaatg ttctacaagg aggtgaagga    300

caagctccta caaggcaggc agtattgggt gcaggcttac ctatttctac tccatgtacc    360

accataaaca aagtttgtgc ttcaggaatg aaagccatca tgatggcctc tcaaagtctt    420

atgtgtggac atcagatcaa gcaagagaca ggctccttag caaaaatatg ctgtcatgtc    480

aggaggtga                                                            489


<210>  372
<211>  889
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (771)..(771)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (781)..(782)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (820)..(820)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (880)..(880)
<223>  n is a, c, g, or t

<400>  372
agagatacta tgagaggtcg catcccatca ccatcacgga tcctatttag gtgacactat     60

agaatcgtcg actctggacc ttggctgtca ctcagttagc gcggcctgcc gggacggcct    120

tcgggcagtg atggattgtc gcaatgtcac ccatctcctg caacaagagc tgaccgaggc    180

ccagaagggc tttcaggatg tggaggccca ggccgccacc tgcaaccaca ctgtgatggc    240

cctaatggct tccctggatg cagagaaggc ccaaggacaa aagaaagtgg aggagcttga    300

gggagagatc actacattaa accataagct tcaggacgcg tctgcagagg tggagcgact    360

gagaagagaa aaccaggtct taagcgtgag aatcgcggac aagaagtact accccagctc    420

ccaggactcc agctccgctg cggcgcccca gctgctgatt gtgctgctgg gcctcagcgc    480

tctgctgcag tgagatccca ggaagctggc acatcttgga aggtccgtcc tgctcggctt    540

ttcgcttgaa cattcccttg atctcatcag ttctgagcgg gtcatggggc aacacggtta    600

gcggggagag cacggggtag ccggagaagg gcctctggag caggtctgga ggggccatgg    660

ggcagtcctg ggtgtgggga cacagtcggg ttgacccagg gctgtctccc tccagagccc    720

tcctccgaca atgagtcccc cctcttgtct ccaccctgag attggcatgg ngtgcggtgt    780

nnggggctgt gctgcctgtg gtatggtttt tttgccgggn ggttgctttt tcctgggcct    840

taactcccaa ataaaccttc ctttgagaaa ccactctttn gaaaaagaa                889


<210>  373
<211>  345
<212>  DNA
<213>  Homo sapiens

<400>  373
atgggcccgc gccgccggag ccgaaagccc gaggccccga ggaggcgcag cccgagcccg     60

accccgaccc ccggcccctc ccggcggggc ccctccttag gcgcttcctc ccatcaacac    120

agtcggcgga gacaaggttg gctaaaggag atccgaaagc ttcagaagag cacacacctc    180

ttgataagga agctgccctt cagccgcctg gcagcagaag catttctagt tcatctcttt    240

gaggacgcct atctcctcac cttacatgca ggccgagtta ctctcttccc aaaggatgtg    300

caactggccc ggaggatccg gggccttgag gagggactcg gctga                    345


<210>  374
<211>  1142
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (907)..(907)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (934)..(934)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (954)..(954)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1004)..(1004)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1008)..(1008)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1014)..(1014)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1026)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1033)..(1033)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1037)..(1037)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1041)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1046)..(1046)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1055)..(1055)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1058)..(1058)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1081)..(1081)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1083)..(1083)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1087)..(1087)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1091)..(1091)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1109)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1113)..(1115)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1123)..(1123)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1131)..(1131)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1134)..(1134)
<223>  n is a, c, g, or t

<400>  374
agagaaatta ctatgagagg atcgcatcac catcaccatc acggatccta tttaggtgac     60

actatagaat cgtcgaccca cgcgtccggg gagaaagaaa aggagaagga gttgcgagct    120

tcaacaaatg ctatgcttat cagtgctgga ttaccacctt tgaaagcttc ccattcagct    180

cactcaaccc actcagcaca ttcaacgcat tcaacacatt ctgctcattc aacgcatgcc    240

ggacatgcag gtcacacgtc acttccacag tgcattaatc cgttcaccaa cttaccccat    300

actcctcgat actatgatat tctaaagaaa cgtcttcagc tccctgtttg ggaatacaag    360

gataggttta cagatattct ggttagacat cagtcctttg tactggttgg tgagactggg    420

tctggtaaaa caacacagat tccacagtgg tgtgtggagt acatgcgatc attaccagga    480

cccaagagag gagttgcctg tacccaaccc aggagagtgg ctgcaatgag tgtggctcag    540

agagttgctg atgagatgga tgtgatgttg ggccaggaag ttggttactc cattcgattt    600

gaagactgca gtagtgcaaa aaccattctt aagtatatga ctgatgggat gttacttcgt    660

gaagctatga atgatcccct cctggagcgt tatggtgtaa taattcttga tgaggctcat    720

gagaggacac tggctacaga tattctaatg ggtgttctga aggaagttgt aagacagaga    780

tcagatttaa aggttatagt tatgagcgct actctagatg caggaaaatt ccagatttac    840

tttgataact gtcctctcct aactattcct gggcgtacac atcctgttga gatcttctat    900

actccanaac cagagagaga ttatcttgaa gcancaattc gaacagttat ccanattcat    960

atgtgtgaaa agaaaaagga aatcttcttc ttttctnaac tggncaanag gaantgatga   1020

acctgnaaaa aanaaancgn naattnagat ttggnccnga aattggggac ttaaaatcat   1080

ncntggnatc naacttcncc tcanagcann aannnttttt ganccccccc nccnaaaaaa   1140

aa                                                                  1142


<210>  375
<211>  3114
<212>  DNA
<213>  Homo sapiens

<400>  375
atggatcgga tggccagctc catgaagcag gtgcccaacc cactgcccaa ggtgctgagc     60

cggcgcgggg tcggcgctgg gctggaggcg gcggagcgcg agagcttcga gcggactcag    120

actgtcagca tcaataaggc cattaatacg caggaagtgg ctgtaaagga aaaacacgcc    180

agaacgtgca tactgggcac ccaccatgag aaaggggcac agaccttctg gtctgttgtc    240

aaccgcctgc ctctgtctag caacgcagtg ctctgctgga agttctgcca tgtgttccac    300

aaactcctcc gagatggaca cccgaacgtc ctgaaggact ctctgagata cagaaatgaa    360

ttgagtgaca tgagcaggat gtggggccac ctgagcgagg ggtatggcca gctgtgcagc    420

atctacctga aactgctaag aaccaagatg gagtaccaca ccaaaaatcc caggttccca    480

ggcaacctgc agatgagtga ccgccagctg gacgaggctg gagaaagtga cgtgaacaac    540

tttttccagt taacagtgga gatgtttgac tacctggagt gtgaactcaa cctcttccaa    600

acagtattca actccctgga catgtcccgc tctgtgtccg tgacggcagc agggcagtgc    660

cgcctcgccc cgctgatcca ggtcatcttg gactgcagcc acctttatga ctacactgtc    720

aagcttctct tcaaactcca ctcctgcctc ccagctgaca ccctgcaagg ccaccgggac    780

cgcttcatgg agcagtttac aaagttgaaa gatctgttct accgctccag caacctgcag    840

tacttcaagc ggctcattca gatcccccag ctgcctgaga acccacccaa cttcctgcga    900

gcctcagccc tgtcagaaca tatcagccct gtggtggtga tccctgcaga ggcctcatcc    960

cccgacagcg agccagtcct agagaaggat gacctcatgg acatggatgc ctctcagcag   1020

aatttatttg acaacaagtt tgatgacatc tttggcagtt cattcagcag tgatcccttc   1080

aatttcaaca gtcaaaatgg tgtgaacaag gatgagaagg accacttaat tgagcgacta   1140

tacagagaga tcagtggatt gaaggcacag ctagaaaaca tgaagactga gagccagcgg   1200

gttgtgctgc agctgaaggg ccacgtcagc gagctggaag cagatctggc cgagcagcag   1260

cacctgcggc agcaggcggc cgacgactgt gaattcctgc gggcagaact ggacgagctc   1320

aggaggcagc gggaggacac cgagaaggct cagcggagcc tgtctgagat agaaaggaaa   1380

gctcaagcca atgaacagcg atatagcaag ctaaaggaga agtacagcga gctggttcag   1440

aaccacgctg acctgctgcg gaagaatgca gaggtgacca aacaggtgtc catggccaga   1500

caagcccagg tagatttgga acgagagaaa aaagagctgg aggattcgtt ggagcgcatc   1560

agtgaccagg gccagcggaa gactcaagaa cagctggaag ttctagagag cttgaagcag   1620

gaacttgcca caagccaacg ggagcttcag gttctgcaag gcagcctgga aacttctgcc   1680

cagtcagaag caaactgggc agccgagttc gccgagctag agaaggagcg ggacagcctg   1740

gtgagtggcg cagctcatag ggaggaggaa ttatctgctc ttcggaaaga actgcaggac   1800

actcagctca aactggccag cacagaggaa tctatgtgcc agcttgccaa agaccaacga   1860

aaaatgcttc tggtggggtc caggaaggct gcggagcagg tgatacaaga cgccctgaac   1920

cagcttgaag aacctcctct catcagctgc gctgggtctg cagatcacct cctctccacg   1980

gtcacatcca tttccagctg catcgagcaa ctggagaaaa gctggagcca gtatctggcc   2040

tgcccagaag acatcagtgg acttctccat tccataaccc tgctggccca cttgaccagc   2100

gacgccattg ctcatggtgc caccacctgc ctcagagccc cacctgagcc tgccgactca   2160

ctgaccgagg cctgtaagca gtatggcagg gaaaccctcg cctacctggc ctccctggag   2220

gaagagggaa gccttgagaa tgccgacagc acagccatga ggaactgcct gagcaagatc   2280

aaggccatcg gcgaggagct cctgcccagg ggactggaca tcaagcagga ggagctgggg   2340

gacctggtgg acaaggagat ggcggccact tcagctgcta ttgaaactgc cacggccaga   2400

atagaggaga tgctcagcaa atcccgagca ggagacacag gagtcaaatt ggaggtgaat   2460

gaaaggatcc ttggttgctg taccagcctc atgcaggcta ttcaggtgct catcgtggcc   2520

tctaaggacc tccagagaga gattgtggag agcggcaggg gtacagcatc ccctaaagag   2580

ttttatgcca agaactctcg atggacagaa ggacttatct cagcctccaa ggctgtgggc   2640

tggggagcca ctgtcatggt ggatgcagct gatctggtgg tacaaggcag agggaaattt   2700

gaggagctaa tggtgtgttc tcatgaaatt gctgctagca cagcccagct tgtggctgca   2760

tccaaggtga aagctgataa ggacagccct aacctagccc agctgcagca ggcctctcgg   2820

ggagtgaacc aggccactgc cggcgttgtg gcctcaacca tttccggcaa atcacagatc   2880

gaagagacag acaacatgga cttctcaagc atgacgctga cacagatcaa acgccaagag   2940

atggattctc aggttagggt gctagagcta gaaaatgaat tgcagaagga gcgtcaaaaa   3000

ctgggagagc ttcggaaaaa gcactacgag cttgctggtg ttgctgaggg ctgggaagaa   3060

ggaacagagg catctccacc tacactgcaa gaagtggtaa ccgaaaaaga atag         3114


<210>  376
<211>  631
<212>  DNA
<213>  Homo sapiens

<400>  376
ctatgagagg tcgcatcacc atcaccatca cggatcctat ttaggtgaca ctatagaatc     60

gtcgactctg gaccttggct gtcactcagt tggagtctct ttgcggcgct acactagagc    120

agagtacgag tctgaggcgg agggagtaat ggcaggacaa gcgtttagaa agtttcttcc    180

actctttgac cgagtattgg ttgaaaggag tgctgctgaa actgtaacca aaggaggcat    240

tatgcttcca gaaaaatctc aaggaaaagt attgcaagca acagtagtcg ctgttggatc    300

gggttctaaa ggaaagggtg gagagattca accagttagc gtgaaagttg gagataaagt    360

tcttctccca gaatatggag gcaccaaggt agttctagat gacaaggatt atttcctatt    420

tagagatggt gacattcttg gaaagtacgt agactgaaat aagtcactat tgaaatggca    480

tcaacatgat gctgcccatt ccactgaagt tctgaaatct ttcgtcatgt aaataatttc    540

catatttctc ttttataata aactaatgat gactaatgac atccagtgtc tccaaaattg    600

tttccttgta ctgatataaa cacttccaaa t                                   631


<210>  377
<211>  601
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (476)..(476)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (499)..(499)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (525)..(525)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (528)..(528)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (531)..(531)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (544)..(544)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (550)..(550)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (552)..(553)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (556)..(556)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (559)..(559)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (561)..(561)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (564)..(564)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (581)..(581)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (590)..(590)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (597)..(599)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (601)..(601)
<223>  n is a, c, g, or t

<400>  377
agagagaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccga gccgctgctg aacaagtggc tggaggaggc    120

ggactcaagc accggcagcc ccacaagcat cgacaagatc gcggcgcagg gccgcaagcg    180

caagaagcgg acctctatcg aggtgagcgt caagggcgcg ctggagagcc acttcctcaa    240

gtgccccaag ccctccgcgc aggagatcac caacctggcc gacagcctgc agctcgagaa    300

ggaggtggtg cgggtctggt tctgcaatcg gcgccaaaag gagaagcgca tgacgccgcc    360

cgggatccaa cagcagacgc ccgacgacgt ctactcgcag gtgggcaccg tgagcgccga    420

cacgccgccg cctcaccacg ggctgcagac gagcgttcag tgaagccagg gcgcanagcg    480

aatagggccg ccgccgccnc cgcctccgca gccgccgtca gcatngcngc ngcccctgcc    540

gccnccgccn cnnccnccnt ncgncgctgc caccgccgcg ncaaccctgn acctggnnng    600

n                                                                    601


<210>  378
<211>  846
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (819)..(819)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (827)..(828)
<223>  n is a, c, g, or t

<400>  378
nttatgagaa atactatgag aggatgcatc ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgactc tggaccttgg ctgtcactca gttttgtggg aaatgacaac    120

acaggtgtca cactactact tggcacagct cactagtgtg aggcagtgga aaactaatga    180

tgatacaatt gattttgatt atactgttct acttcatgaa ttatcaacac aggaaataat    240

tccctgtcgc attcacttgg tctggtaccc tggcaaacct cttaaagtga agtaccactg    300

tcaagagcta cagacaccag aagaagcctc cggaactgaa gaaggatcag ctgtagtacc    360

aacagagctt agtaatttct aaaaagaaaa aatgatcttt ttccgacttc taaacaagtg    420

actatactag cataaatcat tcttctagta aaacagctaa ggtatagaca ttctaataat    480

ttgggaaaac ctatgattac aagtaaaaac tcagaaatgc aaagatgttg gttttttgtt    540

tctcagtctg ctttagcttt taactctgga agcgcatgca cactgaactc tgctcagtgc    600

taaacagtca ccagcaggtt cctcagggtt tcagccctaa aatgtaaaac ctggataatc    660

agtgtatgtt gcaccagaat cagcattttt tttttaactg caaaaaatga tggtctcatc    720

tctgaatttt atttctcatt cttttgacat actatactaa tatatttatg ttgctaattg    780

ctctatctgc atgttaacaa gatatatact tcgatgaang tattatnnga aaattactgt    840

ttaaaa                                                               846


<210>  379
<211>  689
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<400>  379
naatagagag attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cggcaacttc cttcggtcgt cccgaatccg    120

ggttcatccg acaccagccg cctccaccat gccgccgaag ttcgacccca acgagatcaa    180

agtcgtatac ctgaggtgca ccggaggtga agtcggtgcc acttctgccc tggcccccaa    240

gatcggcccc ctgggtctgt ctccaaaaaa agttggtgat gacattgcca aggcaacggg    300

tgactggaag ggcctgagga ttacagtgaa actgaccatt cagaacagac aggcccagat    360

tgaggtggtg ccttctgcct ctgccctgat catcaaagcc ctcaaggaac caccaagaga    420

cagaaagaaa cagaaaaaca ttaaacacag tgggaatatc acttttgatg agattgtcaa    480

cattgctcga cagatgcggc accgatcctt agccagagaa ctctctggaa ccattaaaga    540

gatcctgggg actgcccagt cagtgggctg taatgttgat ggccgccatc ctcatgacat    600

catcgatgac atcaacagtg gtgctgtgga atgcccagcc agttaagcac aaaggaaaac    660

atttcaataa aggatcattt gacaactgg                                      689


<210>  380
<211>  849
<212>  DNA
<213>  Homo sapiens

<400>  380
atggcagttc ccgagacccg ccctaaccac actatttata tcaacaacct caatgagaag     60

atcaagaagg atgagctaaa aaagtccctg tacgccatct tctcccagtt tggccagatc    120

ctggatatcc tggtatcacg gagcctgaag atgaggggcc aggcctttgt catcttcaag    180

gaggtcagca gcgccaccaa cgccctgcgc tccatgcagg gtttcccttt ctatgacaaa    240

cctatgcgta tccagtatgc caagaccgac tcagatatca ttgccaagat gaaaggcacc    300

ttcgtggagc gggaccgcaa gcgggagaag aggaagccca agagccagga gaccccggcc    360

accaagaagg ctgtgcaagg cgggggagcc acccccgtgg tgggggctgt ccaggggcct    420

gtcccgggca tgccgccgat gactcaggcg ccccgcatta tgcaccacat gccgggccag    480

ccgccctaca tgccgccccc tggtatgatc cccccgccag gccttgcacc tggccagatc    540

ccaccagggg ccatgccccc gcagcagctt atgccaggac agatgccccc tgcccagcct    600

ctttctgaga atccaccgaa tcacatcttg ttcctcacca acctgccaga ggagaccaac    660

gagctcatgc tgtccatgct tttcaatcag ttccctggct tcaaggaggt ccgtctggta    720

cccgggcggc atgacatcgc cttcgtggag tttgacaatg aggtacaggc aggggcagct    780

cgcgatgccc tgcagggctt taagatcacg cagaacaacg ccatgaagat ctcctttgcc    840

aagaagtag                                                            849


<210>  381
<211>  480
<212>  DNA
<213>  Homo sapiens

<400>  381
atgcccaagt tttattgtga ctactgcgat acatacctca cccatgactc tccatctgtg     60

agaaagacac actgcagtgg aaggaaacac aaagagaatg tgaaagacta ttatcagaaa    120

tggatggaag agcaggctca gagcctgatt gacaaaacaa cggctgcatt tcaacaagga    180

aagatacctc ctactccatt ctctgctcct cctcctgcag gggcgatgat accacctccc    240

cccagccttc cgggtcctcc tcgccctggt atgatgccag caccccatat ggggggccct    300

cccatgatgc caatgatggg ccctcctcct cctgggatga tgccagtggg acctgctcct    360

ggaatgaggc cgcccatggg aggccatatg ccaatgatgc ctgggccccc aatgatgaga    420

cctcctgccc gtcccatgat ggtgcccact cggcccggaa tgactcgacc agacagataa    480


<210>  382
<211>  567
<212>  DNA
<213>  Homo sapiens

<400>  382
atgaacggag acgacgcctt tgcaaggaga cccacggttg gtgctcaaat accagagaag     60

atccaaaagg ccttcgatga tattgccaaa tacttctcta aggaagagtg ggaaaagatg    120

aaagcctcag agaaaatctt ctatgtgtat atgaagagaa agtatgaggc tatgactaaa    180

ctaggtttca aggccaccct cccacctttc atgtgtaata aacgggccga agacttccag    240

gggaatgatt tggataatga ccctaaccgt gggaatcagg ttgaacgtcc tcagatgact    300

ttcggcaggc tccagggaat ctccccgaag atcatgccca agaagccagc agaggaagga    360

aatgattcgg aggaagtgcc agaagcatct ggcccacaaa atgatgggaa agagctgtgc    420

cccccgggaa aaccaactac ctctgagaag attcacgaga gatctggacc caaaaggggg    480

gaacatgcct ggacccacag actgcctgag agaaaacagc tggtgattta tgaagagatc    540

agcgaccctg aggaagatga cgagtaa                                        567


<210>  383
<211>  1204
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (849)..(849)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (914)..(914)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (916)..(916)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (923)..(923)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (942)..(943)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (948)..(948)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (963)..(963)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (968)..(968)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (974)..(974)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (992)..(992)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1029)..(1029)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1031)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1033)..(1033)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1047)..(1047)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1054)..(1054)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1057)..(1057)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1063)..(1063)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1080)..(1080)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1121)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1126)..(1126)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1129)..(1129)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1131)..(1131)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1138)..(1138)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1142)..(1142)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1148)..(1149)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1158)..(1158)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1163)..(1163)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1168)..(1168)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1172)..(1172)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1183)..(1183)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1188)..(1188)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1190)..(1190)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1193)..(1193)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1195)..(1195)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1197)..(1197)
<223>  n is a, c, g, or t

<400>  383
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc ccacgcgtcc ggtttatcaa gtgagtccca    120

cgtggggccc acgggtgcag gccttttccc tcattgcctg cctgcctccc gcctgctccc    180

tcgggtcacc tctgtccacc ttccagacta cgctcattat tacaccattg ggcccggcat    240

gttcccgtca tctcagatcc ctagctggaa ggactgggct aagcctgggc cctatgacca    300

gcctctggtg aacaccctgc agcgccgcaa agagaagcga gaaccggacc ccaacggggg    360

aggacccact accgccagcg gcccacctgc agcagctgag gaggctcaga gaccacggag    420

catgactgta tcggctgcca ccaggcctgg tgaggagatg gaggcttgtg aggagctggc    480

cctggccctg tctcggggcc tgcagctgga cacccagagg agcagccggg actcgcttca    540

gtgctccagc ggctacagca cccagacaac caccccctgc tgctctgagg acaccatccc    600

ttcccaagtt tcagattatg attatttctc tgtaagtggt gaccaggagg cagatcagca    660

ggagttcgac aagtcctcca ccattccaag aaacagcgac atcagccagt cctaccgacg    720

gatgttccaa gccaagcgtc cagcctcaac tgctggcctc cccaccaccc tgggacctgc    780

tatggtcact ccaggggttg caactatccg acggacccct tccaccaagc cttctgtccg    840

ccggggaanc attggagctg gtcccatccc catcaagaca cccgtgatcc ctgtcaagac    900

cccaaccgtc ccananctcc cangggtgtt gccagcccct cnnatggnca aaaaacgggg    960

gancacancc tgantcccat ctgtggtgag gnccccaagg gtcacaacat gccctcctca   1020

tgtgaacgnc nancttcgtn aacctcnctt cagnccnaac cantatcctg agaacaaaan   1080

ggcattccaa aatgaactaa aacagaaggg aacccaatgc ntgttnccng ncaattcnaa   1140

angacctnna actgaccnag ganttccnag gnaaaaattt aancctcnan ggngnantaa   1200

aaaa                                                                1204


<210>  384
<211>  881
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (608)..(608)
<223>  n is a, c, g, or t

<400>  384
aagagagata ctatgagagg tcgcatcacc atcccatcac ggatcctatt taggtgacac     60

tatagaatcg tcgactctgg accttggctg tcactcagtt acgctgctgg cctccaatga    120

agcctttaaa aagcaggctt ttagtgctag tgaggcggcc aagaagtaca tggaggagaa    180

tgaccagctc aagaagggag ctgctgttga cggaggcaag ttggatgtcg ggaatgctga    240

ggtgaagttg gaggaagaga acaggagcct gaaggctgac ctgcagaagc taaaggacga    300

gctggccagc actaagcaaa aactagagaa agctgaaaac caggttctgg ccatgcggaa    360

gcagtctgag ggcctcacca aggagtacga ccgcttgctg gaggagcacg caaagctgca    420

ggctgcagta gatggtccca tggacaagaa ggaagagtaa gggcctcctt cctcccctgc    480

ctgcagctgg cttccacctg gcacgtgcct gctgcttcct gagagcccgg cctctccctc    540

cagtacttct gtttgtgccc ttctgcttcc cccattccct tccacagctc atagctcgtc    600

atctcggncc ttgtccacac tctccaagca cattacaggg gacctgattg ctacacgttc    660

agaatgcgtt gctgtcatcc tgcttggcct ggccaggcct gacacagcct tggcttccac    720

gcctgaacgt ggagagcacg agtaatttgt agtccgcttg ccgtggggct gaactcctgg    780

tggcttgacg ccctttttgg ttgccccctg gtgttttcct tgacccccaa gaggtgggtg    840

gaagaaggga ctggagttcc ctgagggcaa aaaagttgcc t                        881


<210>  385
<211>  1179
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (887)..(887)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (990)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (998)..(998)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1014)..(1014)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1030)..(1030)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1038)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1056)..(1056)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1064)..(1064)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1087)..(1087)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1100)..(1100)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1112)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1129)..(1129)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1137)..(1137)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1147)..(1147)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1156)..(1156)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1161)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1168)..(1168)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1170)..(1170)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1179)..(1179)
<223>  n is a, c, g, or t

<400>  385
naattagaga aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccggagccag cagtaaggac tggaaaagaa    120

gcattcgcta cgcgggccga cccttgcagt gcctcatcca ggatgggatc ttaaaccctc    180

acgctgcctc ttgcacctgt gctgcctgct gcgacgacat gaccttaagt ggcccagtca    240

ggctttttgt gccttacaaa aggcgcaaga aggagaatga actgcccaca actcccgtca    300

agaaggactc ccccaagaac atcacattgc ttccagccac cgcggctacc accttcaccg    360

tgaccccctc gggacagatc acgacctcgg gggcactgac ctttgaccga gcgtccacgg    420

tagaggccac tgctgtcata tcagagagtc cggcccaggg cgacgtcttc gcaggggcca    480

cagtccaaga ggccagcgtg cagcccccat gcagggccag ccaccctgag cctcactacc    540

ccggctatca ggacagctgc cagatcgcac cgtttccaga agctgcgttg ccaacgtcac    600

atcccaaaat agtgttgaca tccctgcctg cgctggcggt cccacccccg actcccacca    660

aagcggcacc tcccgcgttg gtcaatgggc tggagctgtc agagcagcgg agctggctgt    720

acctagaaga gatggtcaac tccttgctca acacagcgca gcagctgaag acgctgtttg    780

agcaagccaa gcatgccagc acctaccgag aagctgccac aaaccaggcc aagatccacg    840

ctgacgcaaa gcggaaggag cagtcctgcg ttaactgcgg ccgggangct atgaacgagt    900

gcaccggctg ccacaaggtc aactactgct ccaccttctg ccaacgcaag gactggaagg    960

atcaccagca catatgcggc cagtcagcan ctgtcacngt ccaggcaaaa aaantccacn   1020

tggctgaaan cgtgatgnaa aagggaccgt gtgagntcca tcgncccccc tgggaactgg   1080

ggccctncca tcctggaagn ttttgcaggt cnaaggcccc ttgagaatnt ggggganttt   1140

aaaaaanggg gtgggnaagn naaaaaantn ttggaaaan                          1179


<210>  386
<211>  938
<212>  DNA
<213>  Homo sapiens

<400>  386
ggatcgcatc accatcacca tcacggatcc tatttaggtg acactataga atcgtcgacc     60

cacgcgtccg gaggcacaga ggctccggga ggcagcgctg ccccccgcgc cccgcaccgc    120

tgcgggaccc gcgccgcgag aggggcggac ttcggcgcct cgcgcgtccg ccggcgcctg    180

ggttggcgct gcggggcgga ggcggtgtct gagcgccgct ccggctctgc tctctctcga    240

gcttcggcac ccgcccgagc cgctcgcgcg cccgccacct gtctgcccac tcggctgtct    300

gtctgccctc ccgccgccag ctcctgcctc gggcctgccc tctccggtct cggtgctccg    360

aggggcgacg agaagcgcga cggggccgtg gcgcaccggg cagggcgcgc ggggcgcacg    420

gcctgggggc gcacggtgcg gcgccggccc atgaggcttt ccagcgcggg gagcggcagc    480

gccggccggc catggggggt agcctgcggg tggccgttct aggcgccccg ggcgtgggca    540

agacggccat catccgccag ttcctgttcg gtgactaccc cgagcgccac cggcccacgg    600

acgggccgcg cctctaccga cccgcggtgc tgctcgacgg cgccgtctac gacttgagca    660

tccgcgacgg cgacgtcgct ggccccggct cgagccccgg gggtccggag gagtggccag    720

acgctaagga ctggagcttg caggacacgg acgccttcgt gctcgtctac gacatctgca    780

gcccggacag tttcgactac gtgaaggccc tgcggcagcg catcgcggag accaggccgg    840

cgggcgcgcc cgaagcgccc atcctcgtgg taggcaacaa gcgggacagg cagcggctgc    900

gcttcggacc gcggcgcgcg ctggccgccc tagtgcgc                            938


<210>  387
<211>  744
<212>  DNA
<213>  Homo sapiens

<400>  387
gagatactat gagaggtcgc atcccatccc atcacggatc ctatttaggt gacactatag     60

aatcgtcgac tctggacctt ggctgtcact cagttgacct ttctaaggaa gccgagcgga    120

agctgctaac gtgggaatcg gtgcataagg agaactttct gctggcacgc gctagggaca    180

agcgggagag cgactccgag cgtctgaagc gcacgtccca gaaggtggac ttggcactga    240

aacagctggg acacatccgc gagtacgaac agcgcctgaa agtgctggag cgggaggtcc    300

agcagtgtag ccgcgtcctg gggtgggtgg ccgaggccct gagccgctct gccttgctgc    360

ccccaggtgg gccgccaccc cctgacctgc ctgggtccaa agactgagcc ctgctggcgg    420

acttcaagga gaagccccca caggggattt tgctcctaga gtaaggctca tctgggcctc    480

ggcccccgca cctggtggcc ttgtccttga ggtgagcccc atgtccatct gggccactgt    540

caggaccacc tttgggagtg tcatccttac aaaccacagc atgcccggct cctcccagaa    600

ccagtcccag cctgggagga tcaaggcctg gatcccgggc cgttatccat ctggaggctg    660

cagggtcctt ggggtaacag ggaccacaga cccctcacca ctcacagatt cctcacactg    720

gggaaaataa gccatttcag aaag                                           744


<210>  388
<211>  600
<212>  DNA
<213>  Homo sapiens

<400>  388
atggagaact tccgtaaggt gcgctccgaa gaggcgccag cggggtgcgg ggccgaggga     60

ggcggcccgg gctccggccc cttcgcagac ctggcgccgg gcgcggtgca catgcgggtc    120

aaggaaggca gcaagatccg gaacctgatg gccttcgcca ccgccagcat ggcgcagcca    180

gccacgcgcg ccatcgtctt cagcggctgc ggccgggcca ccaccaaaac cgtcacgtgc    240

gccgagatcc tcaagcgccg cctggcgggc ctgcaccagg tcacgcggct gcgctaccgg    300

agcgtacgcg aggtgtggca gagcctcccg cctgggccca cgcagggtca gacgcctggc    360

gagccggccg ctagtctcag cgtacttaag aacgtgcccg gcctcgccat cctactttcc    420

aaggacgcgc tggatccgcg acagcccggc taccagcccc cgaatcccca tcctggtccc    480

tcgtccccgc cagccgcgcc agcgtccaag aggagcctag gggaacccgc agctggagaa    540

ggctccgcga agcgatcgca acccgagcca ggggttgcgg acgaggatca gacggcctga    600


<210>  389
<211>  779
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (636)..(636)
<223>  n is a, c, g, or t

<400>  389
atagagagat tactatgaga ggtcgcatcc catcaccatc acggatccta tttaggtgac     60

actatagaat cgtcgactct ggaccttggc tgtcactcag ttcaacagca tttgatcgag    120

ctgatccgcc agcgggagac agaggcggcg ctggagtttg cacagactca gctggcggag    180

cagggcgagg agagccgaga gtgcctcaca gagatggagc gtaccctggc actgctggcc    240

tttgacagtc ccgaggagtc gcccttcgga gacctcctcc acaccatgca gaggcagaag    300

gtgtggagtg aagttaacca agctgcgcta gattatgaaa atcgcgagtc aacacccaaa    360

ctggcaaaat tactgaaact actactttgg gctcagaacg agctggacca gaagaaagta    420

aaatatccca aaatgacaga cctcagcaag ggtgtgattg aggagcccaa gtagcgcctg    480

cgcttgcgtg gtggatccaa caccagccct gcgtcgtggg acttgcctca gatcagcctg    540

cgactgcaag attcttactg cagtagagaa ctctttttct cccttgtact tttttttgac    600

ctggcatctt tttataggga aaaatggcct ttgtangcag tggaaaactt gcaaggaaag    660

ctgccgtctc tttggcagcc tgatgcaaag cctgcactct ggcactcgct gaagaatctg    720

gaaggttgcg gtttgctctt tccgtgttcg ggggcctctg gctgctgaag ggatcggtc     779


<210>  390
<211>  1198
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (918)..(919)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (969)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1012)..(1012)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1041)..(1041)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1052)..(1052)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1055)..(1055)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1068)..(1068)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1081)..(1081)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1087)..(1089)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1096)..(1096)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1113)..(1113)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1121)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1126)..(1126)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1129)..(1129)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1133)..(1133)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1135)..(1135)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1145)..(1145)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1149)..(1149)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1162)..(1163)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1168)..(1168)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1170)..(1170)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1184)..(1185)
<223>  n is a, c, g, or t

<400>  390
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc acacttctcg gaaaaacaca cactagagca    120

aaaaacagac accagagaaa atccacagga atatccggat ttctatgact tctcaaatgc    180

tgcttgcaga ccttctactc ctgctctcag cagacgcacc ccttcccctt cgcaaggtgg    240

atattttggt cccgatctgt acagccacaa taaggcatca ccaagtggct taaagtcagc    300

ctacctacct ggtcagacgt ctcctaaaaa acaggaagaa gctaggagag aatatccact    360

ttcccctgac gggcatctac acagacaaaa gaatgagccg atacacctgg atgtcgttga    420

gcaacctccc cagcggtcag actttccttt ggcagcccca gaaaatgcta gtaccggtcc    480

agcccatgtc aggggacgaa ctgcagtaga aactgacttg acttttgggc tgactcctaa    540

cagaccttca ctttctgcat gtagctctga agctcccgaa gagagatccg gtagaagact    600

ggcagacagt gagtccctgg gccatggagc tcagagaaat acagatttgg aaagggaaga    660

ttcaataagc agaggaagga ggtcaccaag caagccggac ttcctctaca aaaagtctgc    720

cctctgagag caacctccaa gtcgtctgtg cctgagatgt gaaacatccc attttatgat    780

gtaacccaac aacttacaga ccagttcatc aatgccagct gataactcgg tttcacatga    840

tttggttcta gtttttgtgt atatatgtgt ttattagaca tggcatgcta agaaggtttt    900

gttttttttt tttaatgnng catctgtcta atttgtcttt gaacaattat gtcgggaggc    960

atttttaana acaagcaggc tggcactttt ttatttctct ttacaaatgg anggaatttt   1020

ttttgccctt ggaacattta ntttcccggg antgnatttt aaaacagnan ggtaaacttt   1080

nttgccnnnt ttaaanggac nggnttttcc aanctttttg natttnacnt tcncncacca   1140

acccngggna ttggatggcc cnnaaaangn ttttcttaaa aaanntcggg gttttttt     1198


<210>  391
<211>  903
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (819)..(819)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (843)..(843)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (892)..(892)
<223>  n is a, c, g, or t

<400>  391
cantagagag aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgggaactt gcaccgaagc atcactcgag    120

accccaaacc tccaggcctg aggcccagcc agcgcccaat ggatgacaaa aagaagaaac    180

ggagtcccaa gccctgcctg gcccagccag cccaggcccc aggcacacta cggagggtcc    240

ctgtgcctac cagccacagc ggctccttgg ccctaggact tcctcatctg ccatccccca    300

agcagcgggc caagttcaag agagtaggca aagagaagtg ccgcccagtc ctggctggag    360

gtggaagcgg ctctgcaggc acgcccctgc agcactcctt cctgaccgag gtgactgatg    420

tctatgagat ggagggggga ctcctgaacc tgctcaatga tttccactct ggccggctgc    480

aggccttcgg gaaggaatgc tcctttgagc agctggagca cgttcgggag atgcaggaga    540

agctagcccg gctgcacttc agcctggatg tgtgtgggga ggaggaggac gatgaagagg    600

aagaggatgg ggtcactgag gggctgccag aggagcagaa gaagacaatg gctgaccgta    660

acctggacca gctgcttagc aatctggaag acctcagtaa ttctatccag aagctgcacc    720

tggccgagaa cgccgagcct gaggagcagt ccgctgcgta ggcgtcccac gcaggcccac    780

actgcccctc tcattctctt caaactgtga cttttttana gactcgggcg ggtgttctgc    840

ggncccccag gtgctatggg ggaagggggg cgttgaatgg aattaaaacc anaaaagaaa    900

agc                                                                  903


<210>  392
<211>  1179
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (4)..(6)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1081)..(1081)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1126)..(1126)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1129)..(1129)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1134)..(1135)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1148)..(1148)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1152)..(1152)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1154)..(1154)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1158)..(1158)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1160)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1162)..(1162)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1164)..(1174)
<223>  n is a, c, g, or t

<400>  392
ctcnnnctaa gagatactat gagaggatcg catcaccatc accatcacgg tcgacccacg     60

cgtccgctga acagaaaaga tctggaaggg aaaatagaag agcagcaaca aaccagtcat    120

gaaagaccca ctgatgtagc tcatagccac cttgaacaac agcagagcca tgagacagcc    180

ccccagacag gcctgcagtc aaatgctcca atcattcctc aaggagtcaa tgagcccagc    240

actactacaa gtcagaaatc tggaagcgta accacagaac agctccaaga ggttcttttg    300

tcagcttatg accctcaaat tccaacacgg gctgctgccc tgcgtactct ttcccactgg    360

atagagcaga gagaagcaaa agcccttgag atgcaagaga agcttctcaa gatattcttg    420

gaaaacttgg aacatgaaga cacttttgta tatctatctg caattcaggg ggttgccctg    480

ctgtcagacg tctatcctga gaaaatcttg ccggacttgt tggctcaata tgacagcagc    540

aaagacaagc acacaccaga gaccagaatg aaagtcgggg aagtccttat gcgaatcgtc    600

agggcattag gagacatggt ctcaaagtac cgagaacctt tgatccatac cttcctgagg    660

ggagtgagag atcctgatgg tgctcacagg gccagcagct tggccaacct tgggggagct    720

gtgccagagg ctggactttc tgctgggctc cgtggtccat gaggtaacag cttgccctga    780

tgctgtggcc aaacagatgg gtgaaagtca agtacgcaaa gctgccatac atgggggttg    840

ggctgctgct ttcggggact cagcccaaaa actactggag tggttgacgc cggccctcag    900

gaaccctacc actgctgaac acctaaaggg ttcgggaccc aataccgggc caaatccctg    960

cccagttggc cctaaaaaat cggatgactt ctgaaaaatt cccgttcccc ccaaaaaatt   1020

gaaaaaaaat tttggccttc ccaaacccgg ctccgggaag tgaagaaggn aaaaggccaa   1080

nccccaaacc ggcccagntt tcaaaagggg ccccttcctc ttaggnggnc aaannaaccc   1140

cccggggntt tnanacancn cncnnnnnnn nnnnccccc                          1179


<210>  393
<211>  1168
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (852)..(852)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (892)..(892)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (924)..(924)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (926)..(926)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (932)..(932)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (962)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (967)..(967)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (972)..(972)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1045)..(1045)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1049)..(1049)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1052)..(1052)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1055)..(1056)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1073)..(1073)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1108)..(1109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1113)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1118)..(1119)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1122)..(1122)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1132)..(1132)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1134)..(1134)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1152)..(1152)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1160)
<223>  n is a, c, g, or t

<400>  393
agagaaatta ctatgagagg atcgcatcac catcaccatc acggatccta tttaggtgac     60

actatagaat cgtcgaccca cgcgtccggc ccggcaatgg cggcctcgac ggcctcgcac    120

cggcccatca aggggatctt gaagaacaag acctctacga cttcctctat ggtggcgtcg    180

gccgaacagc cccgcgggaa tgtcgacgag gagctgagca aaaaatccca gaagtgggat    240

gaaatgaaca tcttggcgac gtatcatcca gcagacaaag actatggttt aatgaaaata    300

gatgaaccaa gcactcctta ccatagtatg atgggggatg atgaagatgc ctgtagtgac    360

accgaggcca ctgaagccat ggcgccagac atcttagcca ggaaaaaaaa agcgacaatt    420

tgaaatgaaa aggaagcttc actacaatga aggactcaat atcaaactag ccagacaatt    480

aatttcaaaa gacctacatg atgatgatga agatgaagaa atgttagaga ctgcagatgg    540

agaaagcatg aatacggaag aatcaaatca aggatctact ccaagtgacc aacagcaaaa    600

caaattacga agttcataga cgagatttgt tcaacactgc aattgtttgt tagatgtaaa    660

ccctgtgact atagtacgtt gcttcttgtt cttcacaatt catgacttaa gtaccaaaat    720

gcataccagt tattatatat tgccaagaat taaatgataa acttagagac tgattagact    780

gaaaatgcct aatcgatata tatattcttg tgcctagtac tttaccacaa atacagtgta    840

atatcatcag tnccaaaact gcattacttt tgtaaaaaca ctggttaatt tngtataaga    900

tattatagag ctttttatgc tttnanaagt tnaaccaata tctttggggg ggaactattt    960

tnttttntcc cntgaaatgg ggtagctctt acaagtttat ggatttgatt tttttaaaat   1020

caaagccatt gaacacgggn atttngacng anaannttng gctgaaagan ttnaccctgc   1080

ctcactgatt gccgttaatg aaaaaatnna annttacnnt gnttttcgac cncntttaaa   1140

ttcggtgagt tntttggttn caagaagg                                      1168


<210>  394
<211>  381
<212>  DNA
<213>  Homo sapiens

<400>  394
atgcctgaac cggcaaaatc cgctccggcc cctaaaaagg gctccaagaa agccgtcacc     60

aaagcccaga agaaagacgg caagaagcgc aagcgcagcc gcaaagagag ctactccatc    120

tacgtgtaca aggtgctgaa gcaggtccac cccgacaccg gcatctcgtc caaggccatg    180

ggcatcatga actccttcgt caacgacatc ttcgagcgca tcgcgggaga ggcttcccgc    240

ctggcgcact acaacaagcg ctccaccatc acatcccgcg agatccagac ggccgtgcgc    300

ctgctgctgc ccggcgagct ggccaagcac gccgtgtccg agggcaccaa ggcggtcacc    360

aagtacacca gctccaagtg a                                              381


<210>  395
<211>  1141
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (779)..(779)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (884)..(884)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (906)..(906)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (920)..(920)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (935)..(935)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (942)..(942)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (944)..(944)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (946)..(946)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (953)..(953)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (955)..(955)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (961)..(961)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (968)..(968)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1000)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1022)..(1022)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1028)..(1028)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1035)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1073)..(1073)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1076)..(1077)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1079)..(1079)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1085)..(1085)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1093)..(1093)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1109)..(1109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1114)..(1114)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1129)..(1129)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1133)..(1133)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1135)..(1135)
<223>  n is a, c, g, or t

<400>  395
nantagagaa attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cggagaaaca tcaatggatt ctcgacttca    120

aaggatacat gctgagatta aaaattcact caaaattgat aatcttgatg tgaacagatg    180

cattgaggcc ttggatgaac ttgcttcact tcaggtcaca atgcaacaag ctcagaaaca    240

cacagagatg attactacac tgaaaaaaat acggcgattc aaagttagtc aggtaatcat    300

ggaaaagtct acaatgttgt ataacaagtt taagaacatg ttcttggttg gtgaaggaga    360

ttccgtgatc acccaagtgc tgaataaatc tcttgctgaa caaagacagc atgaggaagc    420

gaataaaacc aaagatcaag ggaagaaagg gccaaacaaa aagctagaga aggaacaaac    480

agggtcaaag actctaaatg gaggatctga tgctcaagat ggtaatcagc cacaacataa    540

cggggagagc aatgaagaca gcaaagacaa ccatgaagcc agcacgaaga aaaagccatc    600

cagtgaagag agagagactg aaatatctct gaaggattct acactagata actaggttga    660

catacctgga atatagagaa cacttgagaa gtttgtaatg gttttcattt gaaatagact    720

gctgaaagtt ttaaattttt ataagcatag gtttgatgtt gaaaacttgt tttgagggna    780

gaaaaatccc tttgttttaa agtaaagtaa acattatcgc taagtgtact tgtgcagtat    840

taacagctac attatacagt aaatgtggga taaaatccat ttanaaaatg ttaaactgct    900

tttccngaca tgggttgtan catattttca attantgtgg gnangnttaa tgngnaaatg    960

naaaatanaa caaagttaca tttttaaaac tgctacttgn nataaaccct tgcccccttt   1020

tnccaaanaa ctggngggtt ttgggcatag ttttttacaa accttggaat ttnccnnanc   1080

gggcnttttc ccngtttggg gggttttgna aaanttaccc ctttttttng ggnanaaaaa   1140

a                                                                   1141


<210>  396
<211>  1252
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (900)..(900)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (936)..(936)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (964)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (985)..(985)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1014)..(1014)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1016)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1023)..(1023)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1032)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1036)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1045)..(1045)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1075)..(1075)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1077)..(1077)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1084)..(1084)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1091)..(1091)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1093)..(1093)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1095)..(1095)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1103)..(1103)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1111)..(1111)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1113)..(1113)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1124)..(1124)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1126)..(1126)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1130)..(1130)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1132)..(1132)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1139)..(1139)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1149)..(1149)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1151)..(1151)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1155)..(1155)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1158)..(1158)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1170)..(1170)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1208)..(1208)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1213)..(1213)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1219)..(1219)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1225)..(1225)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1239)..(1240)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1243)..(1243)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1245)..(1245)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1252)..(1252)
<223>  n is a, c, g, or t

<400>  396
attagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gctcccctcc tcaattcagg agctggtttt    120

ccatccatcc cagtcggcaa gagccccatg gtggagcagg ctgtgcagac tggttctgct    180

gacaacctga atgctaaaaa gctgttacct ggcaagggca ccacagggac gcagctcaac    240

ggtcgtcagg cccagccgag cagcaagacg gccagcgatg tagtccagcc ggcagctgtg    300

caagctcaag ggcaggtgaa tgacgagaac agaagacctc agaggaggcg atcaggaaac    360

aggcgaacaa ggaatcgctc cagagggcaa aaccgtccaa ctaacgttaa ggaaaacaca    420

atcaaatttg agggtgactt tgatttcgag agtgcaaatg cccagttcaa ccgagaggag    480

cttgacaaag aatttaagaa gaaactgaat tttaaagatg acaaggctga gaagggggaa    540

gagaaggacc tggctgtggt gacccagagt gccgaagcgc ccgctgagga agaccttctg    600

gggcccaact gctactatga caaatccaag tcgttcttcg acaacatctc ttctgaactc    660

aagaccagct ccaggcggac gacgtgggcc gaagagagga agctcaacac agagaccttt    720

ggggtgtcag ggaggtttct tcgtggccgc agttctcggg gcggattccg aggaggcagg    780

ggcaatggga ccacccgtcg caaccccact tcccacaggg ccgggactgg cagggtgtga    840

gggtgcagcc aaaggctcct actgaagtgg cgcataactg acgctgtgtg tgtcaggacn    900

cgaggaaaac gctgcactta cagggaaagg gggtcncttt gtttacggag tttggaaaaa    960

cccntactgc tacttgtgtt ttggnactta actgaacttg gaaatgggcc tgantnaaaa   1020

ccnctttttt tngggnaaat attcntgggg taaccccctt tggaggcctt tttancnggg   1080

gttncctttt nantngccca nancccaatt ntnaaggttt tggnantttn cnaaaaggnt   1140

ttctaaaang naaanctnaa cccttacttn gggacttttt ttttttttta tgacaacctt   1200

tacttttnaa aangaaccna atctnttggg aaagggggnn ccnanaattt tn           1252


<210>  397
<211>  1296
<212>  DNA
<213>  Homo sapiens

<400>  397
atgcacgtgc gctcactgcg agctgcggcg ccgcacagct tcgtggcgct ctgggcaccc     60

ctgttcctgc tgcgctccgc cctggccgac ttcagcctgg acaacgaggt gcactcgagc    120

ttcatccacc ggcgcctccg cagccaggag cggcgggaga tgcagcgcga gatcctctcc    180

attttgggct tgccccaccg cccgcgcccg cacctccagg gcaagcacaa ctcggcaccc    240

atgttcatgc tggacctgta caacgccatg gcggtggagg agggcggcgg gcccggcggc    300

cagggcttct cctaccccta caaggccgtc ttcagtaccc agggcccccc tctggccagc    360

ctgcaagata gccatttcct caccgacgcc gacatggtca tgagcttcgt caacctcgtg    420

gaacatgaca aggaattctt ccacccacgc taccaccatc gagagttccg gtttgatctt    480

tccaagatcc cagaagggga agctgtcacg gcagccgaat tccggatcta caaggactac    540

atccgggaac gcttcgacaa tgagacgttc cggatcagcg tttatcaggt gctccaggag    600

cacttgggca gggaatcgga tctcttcctg ctcgacagcc gtaccctctg ggcctcggag    660

gagggctggc tggtgtttga catcacagcc accagcaacc actgggtggt caatccgcgg    720

cacaacctgg gcctgcagct ctcggtggag acgctggatg ggcagagcat caaccccaag    780

ttggcgggcc tgattgggcg gcacgggccc cagaacaagc agcccttcat ggtggctttc    840

ttcaaggcca cggaggtcca cttccgcagc atccggtcca cggggagcaa acagcgcagc    900

cagaaccgct ccaagacgcc caagaaccag gaagccctgc ggatggccaa cgtggcagag    960

aacagcagca gcgaccagag gcaggcctgt aagaagcacg agctgtatgt cagcttccga   1020

gacctgggct ggcaggactg gatcatcgcg cctgaaggct acgccgccta ctactgtgag   1080

ggggagtgtg ccttccctct gaactcctac atgaacgcca ccaaccacgc catcgtgcag   1140

acgctggtcc acttcatcaa cccggaaacg gtgcccaagc cctgctgtgc gcccacgcag   1200

ctcaatgcca tctccgtcct ctacttcgat gacagctcca acgtcatcct gaagaaatac   1260

agaaacatgg tggtccgggc ctgtggctgc cactag                             1296


<210>  398
<211>  861
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (680)..(680)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (730)..(730)
<223>  n is a, c, g, or t

<400>  398
agatactatg agaggtcgca tcccatcacc atcacggatc ctatttaggt gacactatag     60

aatcgtcgac tctggacctt ggctgtcact cagttggaac gaactacatc tcccggcagg    120

ctgcggaagg gggtctagta gaaggaccgc cgctccggcc tcccgcgact tctcgaaggt    180

gggcaggtcc caccttgtgg aggatggagg tgaccgggga cgccggggta ccagaatctg    240

gcgagatccg gactctaaag ccgtgtctgc tgcgccgcaa ctacagccgc gaacagcacg    300

gcgtggccgc ctcctgcctc gaagacctga ggagcaaggc ctgtgacatt ctggccattg    360

ataagtccct gacaccagtc accctggtcc tggcagagga tggcaccata gtggatgatg    420

acgattactt tctgtgtcta ccttccaata ctaagtttgt ggcattggct agtaatgaga    480

aatgggcata caacaattca gatggaggta cagcttggat ttcccaagag tcctttgatg    540

tagatgaaac agacagcggg gcagggttga agtggaagaa tgtggccagg cagctgaaag    600

aagatctgtc cagcatcatc ctcctatcag aggaggacct ccagatgctt gttgacgctc    660

cctgctcaga cctggctcan gaactacgtc ggagttgtgc caccgtccag cggctgcagc    720

acacactccn acaggtgctt gacccaagag aggaagtgcg tcagtccaag cagctcctgc    780

agctgtacct ccaggctttg gagaaagaag gcagcctcct gtcaaagtag gaagagtcca    840

agctggcttt gggtgaggag g                                              861


<210>  399
<211>  1215
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (944)..(944)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (981)..(981)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (992)..(992)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (999)..(999)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1004)..(1004)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1018)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1021)..(1021)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1030)..(1030)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1052)..(1052)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1074)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1111)..(1111)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1118)..(1119)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1150)..(1150)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1153)..(1154)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1177)..(1177)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1179)..(1179)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1202)..(1202)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1209)..(1209)
<223>  n is a, c, g, or t

<400>  399
tanaganatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgttccg ctatcttccc ttctgagtac ctcagcagcc    120

acctggaggc cagactcaac agagccattg tgtggctggc tggctacaat gccacgaccc    180

aggagatcgt acggccttct gagctgttgg caggagtcaa agcatacatt ggtttcatac    240

agtcactggc ccagtttttg ggtgcagatg cttccagagt catccgcaac gccctcctgc    300

agcagacaca accactggat tcctgtgggg aacagacaat caccacactc tacacaaact    360

ggtacctgga aagtctgctt agacaggcaa gcagtgggac catcatcctc tccccagcca    420

tgcaggcctt cgtcagcctg cccagagaag gggagcagaa cttcagtgca gaggagttct    480

ctgacatctc tgagatgcgg gccttggcag aactcctggg cccctatggc atgaagttcc    540

tgagtgaaaa cctgatgtgg catgtgacct ctcagattgt ggagctgaag aagctggtgg    600

tggaaaacat ggacatactt gttcagatca gatccaactt tagcaagccg gacttgatgg    660

cttccctgct gccccagctg acaggggctg aaaatgtgct aaagcgcatg accatcattg    720

gggttatcct cagtttcagg gccatggccc aagagggact tcgggaggtt ttctcctccc    780

actgcccatt tcttatgggt cccattgagt gcttgaagga gttttgtcac tccagacaca    840

gacatcaagg tgaccttgag tatctttgag ctggcatctg ctgcaggtgt gggctgtgac    900

attgacccag ccttggtggc tgccatggct atctgaaagc tganacttca tctcctgaag    960

aagaanataa gggggccggc nggctcttga tnttttggna gttncctccc ctccttgnca   1020

ntgacccttn ttccttttta agccttggaa angagggtta caaaaacatn ttcntggttg   1080

acaaagccat catccagggg nttggggcct nttccgcnnt aaaaaaaaaa attgaaactc   1140

ccccaggaan ttnngggggg gccttttcac cccttgnant ggccagaaat gaaagtttaa   1200

ancaaatcng aaacc                                                    1215


<210>  400
<211>  669
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (639)..(639)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (641)..(641)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (643)..(643)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (648)..(648)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (650)..(653)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (655)..(669)
<223>  n is a, c, g, or t

<400>  400
tactgactta cctataaata ggcgtatcac gaggcccttt cgtcttcacc tcgagaaatc     60

ataaaaaatt tatttgcttt gtgagcggat aacaattata atagattcaa ttgtgagcgg    120

ataacaattt cacacagaat tcattaaaga ggagaaatta actatgagag gatcgcatca    180

ccatcaccat cacggtcgac ccacgcgtcc gcggccgccg ccacccccag gcgcgttggg    240

gccgccgcgc ctggctgcgc tcaaggacga gccacagacg gtgcccgacg tgccgagctt    300

cggcgagagc ccgccgttgt cgcccatcga catggacacg caggagcgca tcaaggcgga    360

gcgcaagcgg ctgcgcaacc gcatcgccgc ctccaagtgc cgcaagcgca agctggagcg    420

catctcgcgc ctggaagaga aagtgaagac cctcaagagt cagaacacgg agctggcgtc    480

cacggcgagc ctgctgcgcg agcaggtggc gcagctcaag cagaaagtcc tcagccacgt    540

caacagcggc tgccagctgc tgccccagca ccaggtgccc gcgtactgag tccgcgcgcg    600

gggcgcatgc gcggccaccc tccccaaggg gcgggctcnc ngnggggngn nnngnnnnnn    660

nnnnnnnnn                                                            669


<210>  401
<211>  735
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (714)..(715)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (734)..(735)
<223>  n is a, c, g, or t

<400>  401
atagagagat tactatgaga ggtcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgactc tggaccttgg ctgtcactca gttaaatcaa tcaacttcat    120

cggaggccag cccctccggc cccagggacc cccgatgatg ccaccttacc ctggtcccgg    180

acattgccat caacagctga acagcctgcc caccatggaa ggacccccaa ccttcaaccc    240

gcctgtgcca tatttcggga ggctgcaagg agggctcaca gctcgaagaa ccatcatcat    300

caagggctat gtgcctccca caggcaagag ctttgctatc aacttcaagg tgggctcctc    360

aggggacata gctctgcaca ttaatccccg cataggcaac ggtaccgtgg tccggaacag    420

ccttctgaat ggctcgtggg gatccgagga gaagaagatc acccacaacc catttggtcc    480

cggacagttc tttgatctgt ccattcgctg tggcttggat cgcttcaagg tttacgccaa    540

tggccagcac ctctttgact ttgcccatcg cctctcggcc ttccagaggg cggacacatt    600

ggaaatccag ggtgatgtca ccttgtccta tgtccagatc taatctattc ctggggccat    660

aactcatggg gaaacagaat tatcccctag gactcctttc taagccccta atannatgtc    720

tgaggggtga aaann                                                     735


<210>  402
<211>  2832
<212>  DNA
<213>  Homo sapiens

<400>  402
atggcccggg gctcggcgct cccgcggcgg ccgctgctgt gcatcccggc cgtctgggcg     60

gccgccgcgc ttctgctctc agtgtcccgg acttcaggtg aagtggaggt tctggatccg    120

aacgaccctt taggacccct tgatgggcag gacggcccga ttccaactct gaaaggttac    180

tttctgaatt ttctggagcc agtaaacaat atcaccattg tccaaggcca gacggcaatt    240

ctgcactgca aggtggcagg aaacccaccc cctaacgtgc ggtggctaaa gaatgatgcc    300

ccggtggtgc aggagccgcg gcggatcatc atccggaaga cagaatatgg ttcacgactg    360

cgaatccagg acctggacac gacagacact ggctactacc agtgcgtggc caccaacggg    420

atgaagacca ttaccgccac tggcgtcctg tttgtgcggc tgggtccaac gcacagccca    480

aatcataact ttcaggatga ttaccacgag gatgggttct gccagcctta ccggggaatt    540

gcctgtgcac gcttcattgg caaccggacc atttatgtgg actcgcttca gatgcagggg    600

gagattgaaa accgaatcac agcggccttc accatgatcg gcacgtctac gcacctgtcg    660

gaccagtgct cacagttcgc catcccatcc ttctgccact tcgtgtttcc tctgtgcgac    720

gcgcgctccc gggcacccaa gccgcgtgag ctgtgccgcg acgagtgcga ggtgctggag    780

agcgacctgt gccgccagga gtacaccatc gcccgctcca acccgctcat cctcatgcgg    840

cttcagctgc ccaagtgtga ggcgctgccc atgcctgaga gccccgacgc tgccaactgc    900

atgcgcattg gcatcccagc cgagaggctg ggccgctacc atcagtgcta taacggctca    960

ggcatggatt acagaggaac ggcaagcacc accaagtcag gccaccagtg ccagccgtgg   1020

gccctgcagc acccccacag ccaccacctg tccagcacag acttccctga gcttggaggg   1080

gggcacgcct actgccggaa ccccggaggc cagatggagg gcccctggtg ctttacgcag   1140

aataaaaacg tacgcatgga actgtgtgac gtaccctcgt gtagtccccg agacagcagc   1200

aagatgggga ttctgtacat cttggtcccc agcatcgcaa ttccactggt catcgcttgc   1260

cttttcttct tggtttgcat gtgccggaat aagcagaagg catctgcgtc cacaccgcag   1320

cggcgacagc tgatggcctc gcccagccaa gacatggaaa tgcccctcat taaccagcac   1380

aaacaggcca aactcaaaga gatcagcctg tctgcggtga ggttcatgga ggagctggga   1440

gaggaccggt ttgggaaagt ctacaaaggt cacctgttcg gccctgcccc gggggagcag   1500

acccaggctg tggccatcaa aacgctgaag gacaaagcgg aggggcccct gcgggaggag   1560

ttccggcatg aggctatgct gcgagcacgg ctgcaacacc ccaacgtcgt ctgcctgctg   1620

ggcgtggtga ccaaggacca gcccctgagc atgatcttca gctactgttc gcacggcgac   1680

ctccacgaat tcctggtcat gcgctcgccg cactcggacg tgggcagcac cgatgatgac   1740

cgcacggtga agtccgccct ggagcccccc gacttcgtgc accttgtggc acagatcgcg   1800

gcggggatgg agtacctatc cagccaccac gtggttcaca aggacctggc cacccgcaat   1860

gtgctagtgt acgacaagct gaacgtgaag atctcagact tgggcctctt ccgagaggtg   1920

tatgccgccg attactacaa gctgctgggg aactcgctgc tgcctatccg ctggatggcc   1980

ccagaggcca tcatgtacgg caagttctcc atcgactcag acatctggtc ctacggtgtg   2040

gtcctgtggg aggtcttcag ctacggcctg cagccctact gcgggtattc caaccaggat   2100

gtggtggaga tgatccggaa ccggcaggtg ctgccttgcc ccgatgactg tcccgcctgg   2160

gtgtatgccc tcatgatcga gtgctggaac gagttcccca gccggcggcc ccgcttcaag   2220

gacatccaca gccggctccg agcctggggc aacctttcca actacaacag ctcggcgcag   2280

acctcggggg ccagcaacac cacgcagacc agctccctga gcaccagccc agtgagcaat   2340

gtgagcaacg cccgctacgt ggggcccaag cagaaggccc cgcccttccc acagccccag   2400

ttcatcccca tgaagggcca gatcagaccc atggtgcccc cgccgcagct ctacatcccc   2460

gtcaacggct accagccggt gccggcctat ggggcctacc tgcccaactt ctacccggtg   2520

cagatcccaa tgcagatggc cccgcagcag gtgcctcctc agatggtccc caagcccagc   2580

tcacaccaca gtggcagtgg ctccaccagc acaggctacg tcaccacggc cccctccaac   2640

acatccatgg cagacagggc agccctgctc tcagagggcg ctgatgacac acagaacgcc   2700

ccagaagatg gggcccagag caccgtgcag gaagcagagg aggaggagga aggctctgtc   2760

ccagagactg agctgctggg ggactgtgac actctgcagg tggacgaggc ccaagtccag   2820

ctggaagctt ga                                                       2832


<210>  403
<211>  1260
<212>  DNA
<213>  Homo sapiens

<400>  403
atgcacttgc tgggcttctt ctctgtggcg tgttctctgc tcgccgctgc gctgctcccg     60

ggtcctcgcg aggcgcccgc cgccgccgcc gccttcgagt ccggactcga cctctcggac    120

gcggagcccg acgcgggcga ggccacggct tatgcaagca aagatctgga ggagcagtta    180

cggtctgtgt ccagtgtaga tgaactcatg actgtactct acccagaata ttggaaaatg    240

tacaagtgtc agctaaggaa aggaggctgg caacataaca gagaacaggc caacctcaac    300

tcaaggacag aagagactat aaaatttgct gcagcacatt ataatacaga gatcttgaaa    360

agtattgata atgagtggag aaagactcaa tgcatgccac gggaggtgtg tatagatgtg    420

gggaaggagt ttggagtcgc gacaaacacc ttctttaaac ctccatgtgt gtccgtctac    480

agatgtgggg gttgctgcaa tagtgagggg ctgcagtgca tgaacaccag cacgagctac    540

ctcagcaaga cgttatttga aattacagtg cctctctctc aaggccccaa accagtaaca    600

atcagttttg ccaatcacac ttcctgccga tgcatgtcta aactggatgt ttacagacaa    660

gttcattcca ttattagacg ttccctgcca gcaacactac cacagtgtca ggcagcgaac    720

aagacctgcc ccaccaatta catgtggaat aatcacatct gcagatgcct ggctcaggaa    780

gattttatgt tttcctcgga tgctggagat gactcaacag atggattcca tgacatctgt    840

ggaccaaaca aggagctgga tgaagagacc tgtcagtgtg tctgcagagc ggggcttcgg    900

cctgccagct gtggacccca caaagaacta gacagaaact catgccagtg tgtctgtaaa    960

aacaaactct tccccagcca atgtggggcc aaccgagaat ttgatgaaaa cacatgccag   1020

tgtgtatgta aaagaacctg ccccagaaat caacccctaa atcctggaaa atgtgcctgt   1080

gaatgtacag aaagtccaca gaaatgcttg ttaaaaggaa agaagttcca ccaccaaaca   1140

tgcagctgtt acagacggcc atgtacgaac cgccagaagg cttgtgagcc aggattttca   1200

tatagtgaag aagtgtgtcg ttgtgtccct tcatattgga aaagaccaca aatgagctaa   1260


<210>  404
<211>  435
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (234)..(234)
<223>  n is a, c, g, or t

<400>  404
gatactatga gaggtcgcat caccatcacc atcacggatc ctatttaggt gacactatag     60

aatcgtcgac tctggacctt ggctgtcact cagttagcaa agaagcagcc cagctttcag    120

aagcagcccc agtgcccaca gagccccagg cctcacagct cctggatctg ctagatctcc    180

tggatggggc ttctggggat gtccagcatc ctccccatct ggacccctcc ccangaggtg    240

ccctggtaca cctgcttgac cttccctgtg tacctccacc cccaactccc atcccagatc    300

tcaaagtgtt tgagcgtgag ggagtacagc tgaatctgtc tttcattcga ccccctgaaa    360

accctgcttt gctgttaatc accatcactg ccaccaactt ctcagagggt gatgtcaccc    420

atttcatctg ccacg                                                     435


<210>  405
<211>  1112
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (868)..(868)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (877)..(877)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (927)..(927)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (962)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (970)..(970)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (979)..(979)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (983)..(983)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (991)..(991)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (996)..(996)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1030)..(1030)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1038)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1050)..(1050)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1053)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1060)..(1060)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1064)..(1064)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1080)..(1080)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1085)..(1085)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1088)..(1089)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1091)..(1091)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1093)..(1093)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1103)..(1103)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1105)..(1105)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1108)..(1108)
<223>  n is a, c, g, or t

<400>  405
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccga cctgatccgg cagcagcttg agttcgaggc    120

ccagcacatc cgctcgctga tggaggagcg cttcggcacc tcggacgaga tggtgcagcg    180

ggcacagatc cgcgcctcgc gcctggagca gattgacaag gagctgctgg aggcgcagga    240

ccgagtgcag cagacggagc cccaggcctt gctggcggtg aagtcggtgc cggtggacga    300

ggaccccgag acagaggtcc ccacacaccc tgaggatggc acccctcagc cgggcaacag    360

caaggtggag gtggtcttct ggctgttgtc catgttggcg acgcgcgacc aggaggatac    420

agcgcgcacg ctgctggcca tgtccagctc gcccgagagc tgcgtggcca tgcgccgctc    480

gggctgtctg cctctgctgc tgcaaatcct ccacggcacc gaggccgcgg ccgggggtcg    540

cgccggggcc ccaggggcac cgggcgccaa ggacgcacgc atgcgcgcca acgcggcgct    600

gcacaacatc gtcttctcgc agccggacca gggcctggcg cgcaaggaga tgcgcgtcct    660

gcacgtgctg gagcagatcc gggcctactg cgagacctgc tgggactggc tgcaggcccg    720

agacggcggg cccgaaggag gtggcgccgg cagcggtgag tgcctggcct ggtgggcccc    780

ctccgcgcaa ttaacgtgca gctagggctt cccgggggat gggcgactag gaacctccag    840

cctttgctgc ctgccttctg gcgtttgnag gctgcantac caggctccgg ccgaggcctg    900

tggggggcat ttgacgttgg gaaaaanaac ccgcccatga tcgtacttgg cgcaaaatta    960

ancgctcggn aaatccctna atncatgnat ngatcngggg taactctgaa aagttgggtg   1020

ccaaaatttn aaaatttntt ttttttgcan ttnaatcccn aaantttaaa attgggggcn   1080

gggcnctnnt nantcaaaac ctngnaantc cc                                 1112


<210>  406
<211>  1626
<212>  DNA
<213>  Homo sapiens

<400>  406
atgtcccagc tggtggaatg cgtccccaac ttttcggagg ggaagaacca ggaggtgatc     60

gacgccatct ctggagccat cacacagacc ccgggctgcg tgctgctgga tgtggacgca    120

ggcccttcca ccaaccgcac cgtgtacacc ttcgtggggc cgccggagtg cgtggtggag    180

ggggccctca acgctgcccg ggtagcttcc cgacttatcg acatgagcag gcaccaagga    240

gagcaccccc gcatgggggc cctagacgtc tgccccttca tccccgtgag gggcgtcagc    300

gtggatgagt gtgtgctctg cgcccaggcc tttggccaga ggctggcaga ggagctggac    360

gtgccagttt acctgtacgg cgaggcagcc aggatggaca gtcgccggac cctgccggcc    420

atccgggccg gggagtacga ggccctccct aagaagctcc agcaggccga ctgggcgccc    480

gactttggtc ccagctcctt tgtccccagt tggggggcca cggccacggg ggcgaggaag    540

ttcctcattg cttttaacat caacctgctc ggcacaaagg agcaagccca ccgcatcgcg    600

ctcaacctgc gggagcaggg ccgcgggaag gaccagccag gacgtctgaa gaaagttcag    660

ggcattggct ggtacctgga tgagaagaac ctggctcagg tgtccaccaa tcttctggac    720

tttgaggtca cggcactgca cacggtctac gaggagacct gccgagaagc acaggagctg    780

agcctcccag tggtgggctc acagctggtg ggcctggtgc ccctgaaggc tctgctggat    840

gcggccgcct tctactgcga gaaggagaac ctcttcatcc tggaggagga gcagcggatc    900

aggctggtgg tgagccggct gggcctggac tccctgtgcc ccttcagccc taaggagcgg    960

atcatcgagt acctggtccc tgagcgcggg cctgagcgag gcctgggcag caagtccctg   1020

cgcgccttcg tgggggaggt gggtgcccgc tctgcggccc ccgggggcgg ctcggtggcg   1080

gcggccgctg cggccatggg tgcggcgctg ggctccatgg tgggcctcat gacctacggg   1140

cggcgccaat tccagtccct ggacacgacg atgcggcgcc tgatcccgcc cttccgcgag   1200

gcttcggcca agctaaccac gctggtggat gccgacgccg aggccttcac cgcctacctg   1260

gaagcaatga ggctccccaa gaacacacct gaggaaaagg acaggcgcac ggcggcccta   1320

caggagggtc tgaggcgggc agtctctgtg ccgctgacgc tggcggagac ggtggcctcg   1380

ctgtggccgg cgctgcagga actggcccgg tgtgggaacc tggcctgccg gtcagacctc   1440

caggtggcgg ccaaagccct ggagatgggc gtgtttggcg catatttcaa cgtgctcatc   1500

aacctgaggg acatcacaga cgaggcattt aaggaccaga tccaccatcg tgtttccagc   1560

ctcctgcagg aagccaagac ccaggctgca ctggtgctgg actgcttgga gacccggcag   1620

gagtga                                                              1626


<210>  407
<211>  877
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (811)..(811)
<223>  n is a, c, g, or t

<400>  407
tagagagata ctatgagagg tcgcatccca tcaccatcac ggatcctatt taggtgacac     60

tatagaatcg tcgactctgg accttggctg tcactcagtt ggtaaaggtc aggccgaggc    120

cggcgcggag aatctgctgt cgcctgcagc tgctcgcctg tctccgtcgg aagggagccc    180

aagctttgca gagaacatga acgattggat gcccatcgcc aaggagtatg atccactcaa    240

agcgggcagc attgatggca ccgatgaaga cccacacgac cgcgcggtct ggagggcaat    300

gctggcacga tatgtcccca acaaaggtgt cataggagat cccctcctca ccctgtttgt    360

ggccagacta aacttgcaga ccaaggagga caaattaaag gaagtctttt cccgctatgg    420

tgacatccgg cggcttcggc tggtcaggga cttggtcaca ggtttttcaa agggctacgc    480

cttcatcgaa tacaaggagg agcgtgccgt gatcaaagct taccgagatg ctggtggcct    540

ggttattgac cagcatgaga tatttgtgga ctacgagctg gaaaggactc tcaaagggtg    600

gatccctcgg cgacttggag gcggtcttgg gggaaaaaag gagtctgggc aactgagatt    660

tgggggacgg gaccggcctt ttcgaaacct attaacttgc cagttgttaa aaacgacctc    720

tatagagagg gaaaacggga aaggcgggag cgatctcgat cccgagaaga cactgggact    780

cgaggacagg gatcgagaca tgacagggcc ngggagagag atggcagaaa gagagcgaca    840

ggtgtggccg acatgactgg agagaggagg acttcaa                             877


<210>  408
<211>  1045
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (905)..(905)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (932)..(932)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (973)..(973)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (985)..(985)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (989)..(989)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1018)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1031)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1042)..(1042)
<223>  n is a, c, g, or t

<400>  408
cnattagaga aattactatg agaggatcgc atcaccatca ccatcacgga atcctattta     60

ggtgacacta tagaatcgtc gacccacgcg tccgcccacg cgtccgccca cgcgtccggt    120

tgtgctcggt gcgctgagct ccgcggctcc gcgagccggt tccgtcccct tcccgccgcc    180

gccatgaagt ggatgttcaa ggaggaccac tcgctggaac acagatgcgt ggagtccgcg    240

aagattcgag cgaaatatcc cgacagggtt ccggtgattg tggaaaaggt ctcaggctct    300

cagattgttg acattgacaa acggaagtac ttggttccat ctgatatcac tgtggctcag    360

ttcatgtgga tcatcaggaa aaggatccag cttccttctg aaaaggcgat cttcctgttt    420

gtggataaga cagtcccaca gtccagccta actatgggac agctttacga gaaggaaaaa    480

gatgaagatg gattcttata tgtggcctac agcggagaga acacttttgg cttctgaggg    540

ccattgctgg gctaggtgca ccgtaactgc ttgtgtatct tgtaaatagc cagccatttt    600

cagttattat accagaacct cttcacatag acctattagt gcatttgtaa ctggatttat    660

ttcttaatat attggaaggt tttgtttcct tagactagta aattatcata cagagtttta    720

ttttgagttt ttctttttgt gcattgtcct catgcctgta ttctccagga aacttgtcct    780

tctggaaatc atattgaatg atatttctat atcgaagtga ggtaggtgcg gtattaaagt    840

gaaagggaag gtgatgcatt tattctgggt tatgcttgaa gtgttagatg gctaagtatt    900

aaaantatcc aaattaaatc cttagcagtc anaacacttg cttccctaga atatgccaac    960

tgccaatcat gtnggactga gctantttnt tcctctttcg naactnttag ggtaatantt   1020

accataaaaa ntttcttaaa anggc                                         1045


<210>  409
<211>  1142
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (908)..(908)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (916)..(916)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (964)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1013)..(1013)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1017)..(1017)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1022)..(1022)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1039)..(1039)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1047)..(1047)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1063)..(1063)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1066)..(1066)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1075)..(1076)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1080)..(1080)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1084)..(1084)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1088)..(1088)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1095)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1097)..(1097)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1102)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1117)..(1117)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1124)..(1124)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1128)..(1128)
<223>  n is a, c, g, or t

<400>  409
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc ccacgcgtcc ggtgacatga atggtgtcat    120

gacaattcaa gcaaaaccgc ttcagcggag acctgcctat tttgctgaca gaacgcagaa    180

tgagaaggag gacaaagcat cgggtggagg ggcaggtgct ctctcctccg caccgcacag    240

actgggacgg gcctcagaca ctcatggatt atcaccttct gcaaagaaaa caccagtgcc    300

ctggaggctg ccttctcttg cttcagattc acagagacta aaaactccca acatctatag    360

tgacgaagtt cttcggggaa caaaactgcc gactggcgtg gaccacatgg cttccccact    420

ggttcaaacg tcacggagca ggttcccccc gctagtcacg gagaccaggg ggcagaatac    480

agcagttcct ggatgccgcc ttgtttctta cagaggaagg catctacaaa accgtgtgtt    540

gagtgccatg cctgacggta cagaacgatc gcgtcttcga gaaagaacag ccaccctgga    600

acggttgtca aggcccagca caacccacac gttccggcag tcggatacac ctcgaaaaag    660

ttcattgaca caaatggaat ttgctgctca cacatggaca ggtcaaagta ttttgacagg    720

ttcacaatat gtgcctaaat cttttcagag gacaactttg actttcaaga ggagattcca    780

agtgacatct tgaaaccacc tcaccagaac cattggagca cctgtggcct cggcacactg    840

cttatcactt gaaaaatgga ggaacaagtg ttatatttat ctgtgtgtct gacagtgtga    900

gatgttanac cgaganaaaa gcaaacaaat aaatcactta atcttgaaca ctttgccctg    960

taangaaagt ggaaagtcaa acccaccnag ctgccttgct gaaancatct ccnaggnttt   1020

gntaggcttt gttcaaaanc ccctganggg ggtttgcant ccntcntttt ntcanngaan   1080

cccnaacnta attnncntgg gnttgntctc ccccccnaat ttantgtnaa aaaaatttat   1140

ct                                                                  1142


<210>  410
<211>  764
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (4)..(7)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (9)..(15)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (442)..(442)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (464)..(464)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (469)..(469)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (509)..(509)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (516)..(516)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (527)..(527)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (537)..(537)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (541)..(541)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (556)..(556)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (579)..(579)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (581)..(582)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (596)..(596)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (619)..(619)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (635)..(636)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (638)..(638)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (678)..(678)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (681)..(682)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (687)..(687)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (694)..(694)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (706)..(706)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (725)..(725)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (730)..(730)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (738)..(739)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (742)..(742)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (745)..(745)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (752)..(752)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (762)..(763)
<223>  n is a, c, g, or t

<400>  410
gncnnnntnn nnnnnattat taagagagaa ttaactatga gaggatcgca tcaccatcac     60

catcacggat cctatttagg tgacactata gaatcgtcga cccacgcgtc cggctcctca    120

ggcaccccgt atctgggcag caagatcagc ctcatctcca aggcgcagat ccgctacgag    180

ggcattctct acaccatcga caccgacaac tccaccgtgg cgctcgccaa agtgaggtcc    240

tttggcactg aagaccgtcc cacagatagg cctgcgcccc ccagagagga gatttatgag    300

tacatcattt tccgaggaag tgacatcaag gatatcactg tgtgtgaacc tccgaaagct    360

cagcacacac tcccgcagga tcccgccatt gttcagtctt ccctgggttc tgcctccgcc    420

tcgcccttcc agccgcacgt gncttacagc ccctttccga gggnatggng cccctacggc    480

ccgttggccg gccagctccc ctgctcagnc agcagntatg ccgcctnccc tggggtntag    540

nagaagttgg taaagnccct ccagcccttc agccggccng nntttccagg ccctangctc    600

cttcctccaa tctcccacna ggccccggtt tccannangt tttggacttt tgttcccttc    660

cagaaaggcc aacaaggnaa nnttttnact tggncccaag gggaangcct tggttttttt    720

tccanttccn ttcccccnng gntcnggtaa anaaagcccc cnna                     764


<210>  411
<211>  850
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (637)..(644)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (646)..(648)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (651)..(651)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (721)..(721)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (788)..(788)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (800)..(800)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (837)..(837)
<223>  n is a, c, g, or t

<400>  411
agagatacta tgagaggatg catcccatca ccatcacgga tcctatttag gtgacactat     60

agaatcgtcg actctggacc ttggctgtca ctcagttaga caagtaacag ctgctcagct    120

tcacctgagg gatccagtgg caattgtaaa actagctatt tatggtatgc tgccaaaaaa    180

ccttcacaga agaacaatga tggaaaggtt gcatcttttt ccagatgagt atattccaga    240

agatattctt aagaatttag tagaggagct tcctcaacca cgaaaaatac ctaaacgtct    300

agatgagtac acacaagaag aaatagacgc cttcccaaga ttgtggactc cacctgaaga    360

ttatcggcta taagagaata agaattgcag aaaataacag tgaagtgatt gaaactttct    420

tctgatgagt ttctctaacc tacaggatgg agtaaaacaa ctgctacagt tcagcacctg    480

ttttatgtgc cgaatcactg tggggaaagg tcaggaaggt atagtccttc aataggaaat    540

tgtaattaaa atataatttt atagaaccat ttttatgtaa tctgatttga atgttatagt    600

tgataataat aaaatcactt acttggttga ctaaaannnn nnnnannnaa naaaaaaaaa    660

acgagcggcc gctccctata gtgagtcgta ttaagcttaa ttagctgagc ttggactcct    720

ngtgatagat ccagtaatga actcagaact ccatctgaat ttgttcaaaa cgctcggttg    780

ccgccggncg ttttttatgn tgaaaatcca gctagcttgc gagattttca gagctangaa    840

gctaaatgga                                                           850


<210>  412
<211>  1189
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (876)..(876)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (892)..(892)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (925)..(925)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (946)..(946)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (954)..(954)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(989)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (993)..(993)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (996)..(996)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (999)..(999)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1008)..(1008)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1014)..(1014)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1019)..(1019)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1030)..(1030)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1073)..(1073)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1082)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1100)..(1100)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1109)..(1109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1112)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1118)..(1118)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1125)..(1125)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1130)..(1130)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1137)..(1137)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1142)..(1142)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1148)..(1148)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1151)..(1153)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1161)..(1161)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1170)..(1170)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1174)..(1174)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1176)..(1176)
<223>  n is a, c, g, or t

<400>  412
naatagagag attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cggtgatata ttcatctgta cccaaaaagc    120

agccaggaat atgtcatacc agggctttac caaagacaat ggcgtggtgc ctgttgttaa    180

ggaattaatg ggggaggaaa ttcttggtgc atcactttct gcacctttaa catcatacaa    240

ggtgatctat gttctcccaa tgctaactat taaggaggat aaaggcactg gtgtggttac    300

aagtgttcct tccgactccc ctgatgatat tgctgccctc agagacttga agaaaaagca    360

agccttacga gcaaaatatg gaattagaga tgacatggtc ttgccatttg agccggtgcc    420

agtcattgaa atcccaggtt ttggaaatct ttctgctgta accatttgtg atgagttgaa    480

aattcagagc cagaatgacc gggaaaaact tgcagaagca aaggagaaga tatatctaaa    540

aggattttat gagggtatca tgttggtgga tggatttaaa ggacagaagg ttcaagatgt    600

aaagaagact attcagaaaa agatgattga cgctggagat gcacttattt acatggaacc    660

agagaaacaa gtgatgtcca ggtcgtcaga tgaatgtgtt gtggctctgt gtgaccagtg    720

gtacttggat tatggagaag agaattggaa gaaacagaca tctcagtgct tgaagaacct    780

ggaaacattc tgtgaggaga ccaggaggaa ttttgaagcc cccttaggtt ggctacaaga    840

acatgcttgc tcaagaactt atggtctagg cactcncctg ccttgggatg ancagtggct    900

gaattgaatc actttctgac tcccnctatt tacatggcat tttacncagt tgcncnccta    960

ttgcaggggg gtaactngca tggacagnna aantcnccnc tgggcntnaa accnccacna   1020

gatgacccan ggaagtttgg gaatatgttt tcttcaagga ggctccattt ncnaaaaact   1080

cnaattgcaa ggaaaaattn aatncgttna ancgggantt gaatnccggn aaccggntga   1140

cnttcccncc nnnggaaaga ntcttgtccn aacncntttc aaataacct               1189


<210>  413
<211>  1375
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (933)..(933)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (942)..(942)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (960)..(960)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (975)..(975)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (981)..(981)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (984)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1017)..(1017)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1020)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1023)..(1023)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1025)..(1025)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1032)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1043)..(1043)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1066)..(1066)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1094)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1107)..(1108)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1115)..(1115)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1119)..(1120)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1122)..(1122)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1143)..(1143)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1147)..(1147)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1157)..(1158)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1177)..(1177)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1183)..(1183)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1189)..(1189)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1192)..(1192)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1195)..(1195)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1200)..(1200)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1202)..(1202)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1213)..(1213)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1221)..(1221)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1223)..(1223)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1229)..(1229)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1233)..(1233)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1240)..(1240)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1248)..(1248)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1253)..(1253)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1255)..(1255)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1257)..(1257)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1272)..(1272)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1278)..(1278)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1291)..(1291)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1314)..(1314)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1317)..(1317)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1321)..(1321)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1327)..(1327)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1329)..(1330)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1341)..(1341)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1345)..(1345)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1358)..(1358)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1367)..(1367)
<223>  n is a, c, g, or t

<400>  413
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc ccacgcgtcc gagactgtct ctgaggcacc    120

acctttgctg ttcagcgatg aagaagagaa ggaggcacaa cttggagtga agtctgtgga    180

taagaaggtt gagagtgcca aggagtcatt aaaatttggg agaactgatg tggctgagtc    240

agaaaaggaa ggacttttga ctagatctgc tcaggaaaca gtcaagcatt ctgatttatt    300

ttcttcatca tccccatggg acaaaggaac caagcctaga accaaaactg ttcttagctt    360

gtttgatgag gaagaggata aaatggaaga tcaaaacatt atccaggctc cacagaaaga    420

agtaggaaag ggctgcgatc ctgatgccca ccccaagagc acaggtgtct tccaggatga    480

agagctgctt ttcagccaca agctccaaaa ggacaatgac ccagatgttg acctttttgc    540

tggcaccaaa aaaaccaagc tgttagagcc aagtgttggg agcctgtttg gggatgatga    600

agatgatgat cttttcagct ctgccaagtc ccagcctttg gtacaagaga aaaagagagt    660

agtgaaaaaa gaccactctg ttaactcttt caaaaaccag aaacatcctg aatccattca    720

aggtagtaaa gaaaaaggca tatggaagcc ggaaacacct caggactcat caggtctcgc    780

tccatttaaa accaaagaac catccactcg gatcgggaag atacaagcaa atttagcgat    840

caacccagcg gccttgctgc ccacagcggc ttcccagatc tctgaagtaa agcctgtttt    900

gccagaattg gcttttcctt catctgaaca canaaggagc cncggtctgg aaagtgtgcn    960

tgtccttccc gggantgggg nagnccggtg tgaattttga tcttccagct caggcanacn   1020

ccntnaacaa gngcaaacaa aanccgtgtt caaaatgaaa gggaancgta aaccccaaac   1080

ccgtgcacct aggnggctgg gtgctcnngg atccncgcnn gnctgagaaa tgaacctccc   1140

ccnaagnacc cttgccnngg gggctgaggg ccctttnccc aanggcccnc gnccnccccn   1200

cnaaaaaccc cgnggaaaaa nanccctgng agncccggcn cccccccncc ccntngnaaa   1260

gggccctgtc cngaaggnaa aaaccccttt naaatcctgg gttttccaaa gggnggngac   1320

ntttttntnn gggaattttt nccgngcggg tttccccngg gaaaaanccc gggaa        1375


<210>  414
<211>  826
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (714)..(714)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (747)..(748)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (784)..(784)
<223>  n is a, c, g, or t

<400>  414
gatagagaga tactatgaga ggtcgcatcc catcaccatc acggatccta tttaggtgac     60

actatagaat cgtcgactct ggaccttggc tgtcactcag ttgatccggt gctgtgcaca    120

ctggtggggg agagtccgac gcgcctggct aggagcgccg accgcagggc ctctacggac    180

cttactagaa aaatgaaacc tgatgaaact cctatgtttg acccaagtct actcaaagaa    240

gtggactgga gtcagaatac agctacattt tctccagcca tttccccaac acatcctgga    300

gaaggcttgg ttttgaggcc tctttgtact gctgacttaa atagaggttt ttttaaggta    360

ttgggtcagc taacagagac tggagttgtc agccctgaac aatttatgaa atcttttgag    420

catatgaaga aatctgggga ttattatgtt acagttgtag aagatgtgac tctaggacag    480

attgttgcta cggcaactct gattatagaa cataaattca tccattcctg tgctaagaga    540

ggaagagtag aagatgttgt tgttagtgat gaatgcagag gaaagcagct tggcaaattg    600

ttattatcaa cccttacttt gctaagcaag aaactgaact gttacaagat tacccttgaa    660

tgtctaccac aaaatgttgg tttctataaa aagtttggat atactgtatc tgangaaaac    720

tacatgtgtc ggaagtttct aaagtannaa tctttgtaga aattgtcaaa ggggctaatg    780

ctancaggct acactcttcc tagagtgaaa tattttgtgc tgcagc                   826


<210>  415
<211>  1329
<212>  DNA
<213>  Homo sapiens

<400>  415
atgggtctgg ccatggagca cggagggtcc tacgctcggg cggggggcag ctctcggggc     60

tgctggtatt acctgcgcta cttcttcctc ttcgtctccc tcatccaatt cctcatcatc    120

ctggggctcg tgctcttcat ggtctatggc aacgtgcacg tgagcacaga gtccaacctg    180

caggccaccg agcgccgagc cgagggccta tacagtcagc tcctagggct cacggcctcc    240

cagtccaact tgaccaagga gctcaacttc accacccgcg ccaaggatgc catcatgcag    300

atgtggctga atgctcgccg cgacctggac cgcatcaatg ccagcttccg ccagtgccag    360

ggtgaccggg tcatctacac gaacaatcag aggtacatgg ctgccatcat cttgagtgag    420

aagcaatgca gagatcaatt caaggacatg aacaagagct gcgatgcctt gctcttcatg    480

ctgaatcaga aggtgaagac gctggaggtg gagatagcca aggagaagac catttgcact    540

aaggataagg aaagcgtgct gctgaacaaa cgcgtggcgg aggaacagct ggttgaatgc    600

gtgaaaaccc gggagctgca gcaccaagag cgccagctgg ccaaggagca actgcaaaag    660

gtgcaagccc tctgcctgcc cctggacaag gacaagtttg agatggacct tcgtaacctg    720

tggagggact ccattatccc acgcagcctg gacaacctgg gttacaacct ctaccatccc    780

ctgggctcgg aattggcctc catccgcaga gcctgcgacc acatgcccag cctcatgagc    840

tccaaggtgg aggagctggc ccggagcctc cgggcggata tcgaacgcgt ggcccgcgag    900

aactcagacc tccaacgcca gaagctggaa gcccagcagg gcctgcgggc cagtcaggag    960

gcgaaacaga aggtggagaa ggaggctcag gcccgggagg ccaagctcca agctgaatgc   1020

tcccggcaga cccagctagc gctggaggag aaggcggtgc tgcggaagga acgagacaac   1080

ctggccaagg agctggaaga gaagaagagg gaggcggagc agctcaggat ggagctggcc   1140

atcagaaact cagccctgga cacctgcatc aagaccaagt cgcagccgat gatgccagtg   1200

tcaaggccca tgggccctgt ccccaacccc cagcccatcg acccagctag cctggaggag   1260

ttcaagagga agatcctgga gtcccagagg ccccctgcag gcatccctgt agccccatcc   1320

agtggctga                                                           1329


<210>  416
<211>  1075
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (674)..(674)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (683)..(683)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (720)..(720)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (733)..(733)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (807)..(807)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (813)..(813)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (815)..(815)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (817)..(817)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (824)..(824)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (833)..(833)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (836)..(836)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (853)..(853)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (866)..(866)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (874)..(874)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (878)..(878)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (886)..(886)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (911)..(911)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (914)..(914)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (919)..(919)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (924)..(925)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (935)..(935)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (946)..(946)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (951)..(952)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (958)..(958)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (968)..(968)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (973)..(973)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (999)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1017)..(1017)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1019)..(1019)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1053)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1055)..(1055)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1058)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1062)..(1062)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1066)..(1066)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1072)..(1072)
<223>  n is a, c, g, or t

<400>  416
tagagaaatt aactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg cccacgcgtc cgggggcgcc cgaccccgcc    120

gccgccgcag cggcgcgcag cccccgacgc gccctgtggg gacccggacc aggagggacc    180

ctgccccggg aaaaggctgt ggagacctgg gctccgaccc cagttcatcc ccccacaccc    240

ccgccgcccc gtgccaccct ggtccgcgct gggaacccta tcctgcccct cgtgtcagcc    300

cggcactggc cagaatcgcg ggcatggcgg tgaccatgct gcaggactgg tgccggtgga    360

tgggggtcaa cgctcgcagg ggcctgctca tcctgggcat cccggaggac tgtgatgatg    420

ccgaattcca agagtccctc gaggctgccc tgaggcctat gggacacttt acagtgctag    480

gcaaagcgtt tcgagaggag gataatgcca ccgcggccct ggtcgagctc gaccgggaag    540

tcaactatgc tttggtcccc agggaaatcc ccggcactgg gggcccgtgg aacgtggtct    600

ttgtgccccg ttgctcaggc gaggagtttc tcggtctcgg tcgcgtgttc cacttcccgg    660

agcaagaggg gcanatggtg ganagcgtgg ccggcgccct gggtgtgggg ctgcgcaagn    720

tgtgctggct gcnatccatc ggtcaggcgg tccagccctg ggtggaagcc gtgaggtgcc    780

aaaacctggg gtgtgttttc cgggaangac cancnanccc ccangggaag gantcntttg    840

aagttttggc tanaaccaca ccaccnaaat gctncatntg tggcangggg ttctcgaaaa    900

ggaaaaagaa naanaagtnt tttnnaaagt tttgnttggg aacccncctt nnaatttntt    960

ggaaancnct tcntggngaa aaaacccccc caggaaagnn ncaanaattt tttgngngnt   1020

cctgggccca atttttttga aaaaaaaaaa ttncnaanna anattngggg tnaaa        1075


<210>  417
<211>  273
<212>  DNA
<213>  Homo sapiens

<400>  417
atgaagttct tagcagtcct ggtactcttg ggagtttcca tctttctggt ctctgcccag     60

aatccgacaa cagctgctcc agctgacacg tatccagcta ctggtcctgc tgatgatgaa    120

gcccctgatg ctgaaaccac tgctgctgca accactgcga ccactgctgc tcctaccact    180

gcaaccaccg ctgcttctac cactgctcgt aaagacattc cagttttacc caaatgggtt    240

ggggatctcc cgaatggtag agtgtgtccc tga                                 273


<210>  418
<211>  1089
<212>  DNA
<213>  Homo sapiens

<400>  418
atggcggagg taccgcctgg gcctagcagc ctcctcccac caccagcacc tccggccccg     60

gcggcggtcg agccccgctg tcccttcccg gcgggggccg ccctcgcctg ctgcagcgag    120

gacgaggagg acgacgaaga gcacgaaggc ggcggcagca ggagcccggc gggcggagag    180

tcggcgacgg tggcggccaa ggggcatccg tgcctccgct gccctcagcc gccgcaggag    240

cagcagcagc tcaacggatt gattagcccc gaactgcggc acctccgggc ggccgcctcc    300

ctcaagagca aggtcctgag cgtagcagag gtggccgcga ccacagccac ccctgacgga    360

ggccccagag cgactgcaac aaaaggagcc ggggtacact cgggcgagag gccccctcac    420

tccctctcta gtaatgcaag aactgcggtc cccagcccgg tggaggcagc ggcggcgagc    480

gatcccgcgg cggcccgcaa tggactggcc gagggcaccg agcaggagga ggaggaggaa    540

gacgagcagg tgcggctgct gtcttcgtcc ctgaccgccg actgcagctt aagaagccct    600

tcgggcaggg aggttgagcc tggggaggat cggacgatac gatatgtccg atatgaatcc    660

gagctacaaa tgcccgatat catgagactg atcaccaaag atctgtccga accctactcc    720

atttatacct atagatattt tatccacaac tggccacagc tgtgcttctt ggccatggta    780

ggggaggagt gtgtaggtgc catcgtttgc aagttggata tgcacaaaaa gatgttccgc    840

agaggttata tagccatgtt agccgtggat tccaaataca ggagaaatgg cattggtact    900

aacttggtta agaaagctat atatgccatg gttgagggag actgtgatga ggttgttttg    960

gaaaccgaaa taacaaataa gtccgctttg aaactttatg aaaatcttgg ttttgttcga   1020

gataagaggc tgttcagata ctatttaaat ggagttgatg cactgcgact taaactgtgg   1080

ctgcgttga                                                           1089


<210>  419
<211>  1311
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (781)..(781)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (932)..(932)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1283)..(1284)
<223>  n is a, c, g, or t

<400>  419
atcgacttac ctataaatag gcgtatccga ggccctttcg tcttcacctc gagaaatcat     60

aaaaaattta tttgctttgt gagcggataa caattataat agattcaatt gtgagcggat    120

aacaatttca cacagaattc attaaagagg agaaattaac tatgagagga tcgcatcacc    180

atcaccatca cggtcgaccc acgcgtccgg ttgtccctaa tgaggaagat tggaagaaga    240

ggctggagtt gaggaaggaa gtagagggag atgatgtgcc tgaatctata atgctggaga    300

tgaaagccaa cttctctttg cctgaaaaat gcgactatat ggatgaggtg acatatgggg    360

agctggagaa ggaggaagct cagcccattg tcactaagta caaggaggag gcaaggaagc    420

ttctgccccc ctccgagaag cggacaaatc gccgaaacaa ccgaaacaag cgtaaccggc    480

agaaccgaag ccggggccaa ggctatgtgg gcgggcagcg ccgaggctac gacaaccggg    540

cctacgggca gcagtactgg gggcagcctg gaaacagagg gggttaccgt aatttctatg    600

atcgatacag gggagactat gatcgatttt acgggcgaga ttatgagtac aacagataca    660

gagactatta cagacaacgg ccgcgatccg catgcgagct cgattagctg agcttggact    720

cctgttgata gatccagtaa tgacctcaga actccatctg gatttgttca aaacgctcgg    780

ntgccgccgg gcgtttttta ttggtgagaa tccaagctag cttggcgaga ttttcaggag    840

ctaaggaagc taaaatggag aaaaaaatca ctggatatac caccgttgat atatcccaat    900

ggcatcgtaa agaacatttt ggagcatttc antcagttgc ttcatgtacc tataaccaaa    960

ccggtcagct ggatattacg gcccttttaa aaaccgaaaa aaaaataacc acaagtttta   1020

tccgcccttt attccattcc tgcccgcctg aaggaagctc acccggaatt tctatggcat   1080

gaaaaacggg aactggggga atgggaaaag gttcccccct gttaacccgt ttccatagcc   1140

aacgaaaagt ttcctcccct ggagggaata accaaaaatt ccgcaatttc tccctatatc   1200

ccaaaatggg ggggtagggg aaaaccgcca tatccccaag ggttatgaaa aatgttttcc   1260

cccccccccc gggggagtcc cannttgtat aaaggggcaa agaaaatgtc g            1311


<210>  420
<211>  643
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (627)..(627)
<223>  n is a, c, g, or t

<400>  420
gatagagaga tactatgaga ggtcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgactc tggaccttgg ctgtcactca gttgatacag tgacctcggg    120

cggtgggtca cgtcggccgg gcatggctgc atggagcccg gccgcggcag cgcctctcct    180

ccgcgggatc cgcgggcttc cacttcacca tcggatgttt gccactcaga ctgaggggga    240

gctcagagtg acccaaattc tcaaagaaaa gtttccacga gctacagcta taaaagtcac    300

tgacatttca ggaggttgtg gggcgatgta tgaaattaaa attgaatcag aagaatttaa    360

ggagaagaga actgtccagc agcaccagat ggttaatcag gcactaaaag aagaaatcaa    420

agagatgcat ggattgcgga tatttacctc tgtccccaaa cgctgaccac gccctggctg    480

catagatgct gctgcttaag accttggatg aacttcactg acatcattct tccctaagca    540

gtcaccaaaa aaatttatat attttgctca tatacatttc catattataa ttatagaaga    600

tgtgtagtct atttagatgt taattanagg aaacaaacaa ctg                      643


<210>  421
<211>  1125
<212>  DNA
<213>  Homo sapiens

<400>  421
atgctgtcca catctcgttc tcggtttatc agaaatacca acgagagcgg tgaagaagtc     60

accacctttt ttgattatga ttacggtgct ccctgtcata aatttgacgt gaagcaaatt    120

ggggcccaac tcctgcctcc gctctactcg ctggtgttca tctttggttt tgtgggcaac    180

atgctggtcg tcctcatctt aataaactgc aaaaagctga agtgcttgac tgacatttac    240

ctgctcaacc tggccatctc tgatctgctt tttcttatta ctctcccatt gtgggctcac    300

tctgctgcaa atgagtgggt ctttgggaat gcaatgtgca aattattcac agggctgtat    360

cacatcggtt attttggcgg aatcttcttc atcatcctcc tgacaatcga tagatacctg    420

gctattgtcc atgctgtgtt tgctttaaaa gccaggacgg tcacctttgg ggtggtgaca    480

agtgtgatca cctggttggt ggctgtgttt gcttctgtcc caggaatcat ctttactaaa    540

tgccagaaag aagattctgt ttatgtctgt ggcccttatt ttccacgagg atggaataat    600

ttccacacaa taatgaggaa cattttgggg ctggtcctgc cgctgctcat catggtcatc    660

tgctactcgg gaatcctgaa aaccctgctt cggtgtcgaa acgagaagaa gaggcatagg    720

gcagtgagag tcatcttcac catcatgatt gtttactttc tcttctggac tccctataat    780

attgtcattc tcctgaacac cttccaggaa ttcttcggcc tgagtaactg tgaaagcacc    840

agtcaactgg accaagccac gcaggtgaca gagactcttg ggatgactca ctgctgcatc    900

aatcccatca tctatgcctt cgttggggag aagttcagaa gcctttttca catagctctt    960

ggctgtagga ttgccccact ccaaaaacca gtgtgtggag gtccaggagt gagaccagga   1020

aagaatgtga aagtgactac acaaggactc ctcgatggtc gtggaaaagg aaagtcaatt   1080

ggcagagccc ctgaagccag tcttcaggac aaagaaggag cctag                   1125


<210>  422
<211>  351
<212>  DNA
<213>  Homo sapiens

<400>  422
atgagttggc gaggaagatc gacctatcgg cctagaccaa gacgctacgt agagcctcct     60

gaaatgattg ggcctatgcg gcccgagcag ttcagtgatg aagtggaacc agcaacacct    120

gaagaagggg aaccagcaac tcaacgtcag gatcctgcag ctgctcagga gggagaggat    180

gagggagcat ctgcaggtca agggccgaag cctgaagctg atagccagga acagggtcac    240

ccacagactg ggtgtgagtg tgaagatggt cctgatgggc aggagatgga cccgccaaat    300

ccagaggagg tgaaaacgcc tgaagaaggt gaaaagcaat cacagtgtta a             351


<210>  423
<211>  1191
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (876)..(876)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (918)..(918)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (930)..(930)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (991)..(991)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1000)..(1000)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1018)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1025)..(1025)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1078)..(1079)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1088)..(1088)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1099)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1107)..(1108)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1114)..(1114)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1116)..(1116)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1121)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1123)..(1123)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1134)..(1134)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1136)..(1136)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1141)..(1141)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1148)..(1148)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1157)..(1157)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1166)..(1166)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1170)..(1170)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1175)..(1176)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1178)..(1178)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1180)..(1181)
<223>  n is a, c, g, or t

<400>  423
gagaaaatta ctatgagagg atcgcatcac catcaccatc acggatccta tttaggtgac     60

actatagaat cgtcgaccca cgcgtccgcg ctccgggagc tgccgacgga cggagcgccc    120

ccgcccccgc ccggccgccc gcccgccgcc gccatgccct tctccaacag ccacaacgca    180

ctgaagctgc gcttcccggc cgaggacgag ttccccgacc tgagcgccca caacaatcac    240

atggccaagg tgctgacccc cgagctgtac gcggagctgc gcgccaagag cacgccgagc    300

ggcttcacgc tggacgacgt catccagaca ggcgtggaca acccgggcca cccgtacatc    360

atgaccgtgg gctgcgtggc gggcgacgag gagtcctacg aagtgttcaa ggatctcttc    420

gaccccatca tcgaggaccg gcacggcggc tacaagccca gcgatgagca caagaccgac    480

ctcaaccccg acaacctgca gggcggcgac gacctggacc ccaactacgt gctgagctcg    540

cgggtgcgca cgggccgcag catccgtggc ttctgcctcc ccccgcactg cagccgcggg    600

gagcgccgag ccatcgagaa gctcgcggtg gaagccctgt ccagcctgga cggcgacctg    660

gcgggccgat actacgcgct caagagcatg acggaggcgg agcagcagca gctcatcgac    720

gaccacttcc tcttcgacaa gcccgtgtcg cccctgctgc tggcctcggg catggcccgc    780

gactggcccg acgcccgcgg tatctggcac aatgacaata agaccttcct ggtgtgggtc    840

aacgaggagg accacctgcg ggtcatctcc atgcanaagg ggggcaacat gaaggaggtg    900

ttcacccgct tctgcacngg cctcacccan attgaaaact ctcttcagtc taaggactat    960

gagttcatgt ggaaaccctc acctgggcta natcctcacn tgcccatcca acctgggnac   1020

cgggntgcgg gcaggtgtgc atatcagctg cccaacttgg ggcaaacatg aaaatttnnc   1080

ggaagtgntt aagcgggtnn naatttnnaa aacnanggca nanggggggg tggnanccgg   1140

nttggggngg ggggggnttt ttaaantttn caaanntnan ncctgggttt t            1191


<210>  424
<211>  1092
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (25)..(25)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (908)..(908)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (914)..(914)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (920)..(920)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (941)..(941)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(957)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (962)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (967)..(967)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (986)..(986)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (994)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1019)..(1020)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1027)..(1027)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1036)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1045)..(1045)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1049)..(1050)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1052)..(1052)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1054)..(1054)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1064)..(1064)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1079)..(1079)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1081)..(1081)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1083)..(1083)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1086)..(1086)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1090)..(1090)
<223>  n is a, c, g, or t

<400>  424
atngagaaat tactatgaga ggatngcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg gcaggagctg tcgggaagat cagaagccag    120

tcatggatga ccagcgcgac cttatctcca acaatgagca actgcccatg ctgggccggc    180

gccctggggc cccggagagc aagtgcagcc gcggagccct gtacacaggc ttttccatcc    240

tggtgactct gctcctcgct ggccaggcca ccaccgccta cttcctgtac cagcagcagg    300

gccggctgga caaactgaca gtcacctccc agaacctgca gctggagaac ctgcgcatga    360

agcttcccaa gcctcccaag cctgtgagca agatgcgcat ggccaccccg ctgctgatgc    420

aggcgctgcc catgggagcc ctgccccagg ggcccatgca gaatgccacc aagtatggca    480

acatgacaga ggaccatgtg atgcacctgc tccagaatgc tgaccccctg aaggtgtacc    540

cgccactgaa ggggagcttc ccggagaacc tgagacacct taagaacacc atggagacca    600

tagactggaa ggtctttgag agctggatgc accattggct cctgtttgaa atgagcaggc    660

actccttgga gcaaaagccc actgacgctc caccgaaaga gtcactggaa ctggaggacc    720

cgtcttctgg gctgggtgtg accaagcagg atctgggccc agtccccatg tgagagcagc    780

agaggcggtc ttcaacatcc tgccagcccc acacagctac agctttcttg ctcccttcag    840

cccccagccc ctcccccatc tcccaccctg tgcctcatcc catgaaaccc tggtgcctgg    900

ctctttcntc accnttggan aaaaaaacca agtcggaaca ncaaataaca atgcannaag    960

gncctgntgc ccaatctcca tttgtnaaag gggnntgagg tcccagaagt ggccaaaann   1020

taaaaanatc ccgttnctta aaatnaaann ancntccaaa aaanggttcc aaaaactang   1080

ntnttngaan aa                                                       1092


<210>  425
<211>  1006
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (751)..(751)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (776)..(776)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (822)..(822)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (853)..(853)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (861)..(861)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (863)..(864)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (866)..(866)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (871)..(871)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (901)..(901)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (904)..(904)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (908)..(908)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (910)..(910)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (918)..(918)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (926)..(926)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (932)..(932)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (939)..(939)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (941)..(941)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (948)..(948)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (979)..(979)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (995)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (998)..(998)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1003)..(1003)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<400>  425
gantagagag attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cgccggagga gaacgggcgg agggcgcggg    120

ccgaccgggc gcaccgacca tggcctccaa atgccccaag tgcgacaaga ccgtgtactt    180

cgccgagaag gtgagctccc tggggaagga ctggcacaag ttctgcctca agtgcgagcg    240

ctgcagcaag acgctgacgc ccgggggcca cgccgagcat gacgggaagc cgttctgcca    300

caagccgtgc tacgccaccc tgttcggacc caaaggtgag ctccggctgc cctcggcctg    360

ccctgggacc tgctgggagg ggcgtggcgc tggcgctggg gagggctggg ggtcccggcc    420

gccgtggatc cccgcccaga gtccctgcca ccctggaaag cctagtgccc cccagtcccc    480

agcgggccgt tttctgagat gcccggtggc cgcggccccc accccacgta cccccgcccc    540

acgtaccccc acccgcaggc gtgaacatcg ggggcgcggg ctcctacatc tacgagaagc    600

ccctggcgga ggggccgcag gtcaccggcc ccatcgaggt ccccgcggcc cgagcagagg    660

agcggaaggc gagcggcccc ccgaaggggc ccagcagagc ctccagtgtc accactttca    720

ccggggagcc caacacgtgc ccgcgctgca ncaagaaggt gtacttcgct gaaaangtga    780

cgtctctggg caaggattgg caccggccct gcctgcgctg cnagcgctgc gggaaaaaca    840

ctgacccccc ggncgggcac ncnnangtga ngggggtgca aacggggctt ggggggccgg    900

ncangggncn cggggtcngg gggatnaagg tnaaaagcnc ncctaaangg attggggggt    960

ggtgcttctg ggaactncnt tnccttttcc cccanggnaa ncngnc                  1006


<210>  426
<211>  1185
<212>  DNA
<213>  Homo sapiens

<400>  426
atacatttaa gagggagaat taactatgag aggatcgcat caccatcacc atcacggatc     60

ctatttaggt gacactatag aatcgtcgac ccacgcgtcc gcccacgcgt ccgcccacgc    120

gtccgcaacg aggacggggg agtgcgactg cgtctcgggc agcatggccg agaagcggca    180

cacacgggac tccgaagccc agcggctccc cgactccttc aaggacagcc ccagtaaggg    240

ccttggacct tgcggatgga ttttggtggc gttctcattc ttattcaccg ttataacttt    300

cccaatctca atatggatgt gcataaagat tataaaagag tatgaaagag ccatcatctt    360

tagattgggt cgcattttac aaggaggagc caaaggacct ggtttgtttt ttattctgcc    420

atgcactgac agcttcatca aagtggacat gagaactatt tcatttgata ttcctcctca    480

ggagatcctc acaaaggatt cagtgacaat tagcgtggat ggtgtggtct attaccgcgt    540

tcagaatgca accctggctg tggcaaatat caccaacgct gactcagcaa cccgtctttt    600

ggcacaaact actctgagga atgttctggg caccaagaat ctttctcaga tcctctctga    660

cagagaagaa attgcacaca acatgcagtc tactctggat gatgccactg atgcctgggg    720

aataaaggtg gagcgtgtgg aaattaagga tgtgaaacta cctgtgcagc tccagagagc    780

tatggctgca gaagcagaag cgtcccgcga ggcccgcgcc aaggttattg cagccgaagg    840

agaaatgaat gcatccaggg ctctgaaaga agcctccatg gtcatcactg aatctcctgc    900

agcccttcag ctccgatacc tgcagacact gaccaccatt gctgctgaga aaaactcaac    960

aattgtcttc cctctgccca tagatatgct gcaaggaatc ataggggcaa aacacagcca   1020

tctaggctag tgtagagatg agcgctagcc ttccaagcat gagtcgggga ctaattagcc   1080

tttactcata aagaagagta ggctttttct ttttccatat gtcaaattgt tgtgtcccag   1140

gatgtatagc aggtataaaa tagtgaaaga attgttagcc ttgta                   1185


<210>  427
<211>  1196
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (834)..(834)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (891)..(891)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (920)..(920)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (976)..(976)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (987)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (990)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (994)..(994)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (996)..(996)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1021)..(1021)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1034)..(1034)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1041)..(1041)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1044)..(1045)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1053)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1056)..(1056)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1064)..(1064)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1078)..(1078)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1082)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1092)..(1092)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1097)..(1097)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1107)..(1107)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1112)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1120)..(1120)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1122)..(1122)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1125)..(1127)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1134)..(1134)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1140)..(1140)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1149)..(1149)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1157)..(1157)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1159)..(1159)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1167)..(1167)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1169)..(1169)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1179)..(1179)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1181)..(1181)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1196)..(1196)
<223>  n is a, c, g, or t

<400>  427
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccga gccagtggac gtggtagaca acgctgatgg    120

cacccagacc gtcaattatg tgcccagccg agaagggccc tacagcatct cagtactgta    180

tggagatgaa gaggtacccc ggagcccctt caaggtcaag gtgctgccta ctcatgatgc    240

cagcaaggtg aaggccagtg gccccgggct caacaccact ggcgtgcctg ccagcctgcc    300

cgtggagttc accatcgatg caaaggacgc cggggagggc ctgctggctg tccagatcac    360

ggatcccgaa ggcaagccga agaagacaca catccaagac aaccatgacg gcacgtatac    420

agtggcctac gtgccagacg tgacaggtcg ctacaccatc ctcatcaagt acggtggtga    480

cgagatcccc ttctccccgt accgcgtgcg tgccgtgccc accggggacg ccagcaagtg    540

cactgtcaca ggtgctggca tcggccccac cattcagatt ggggaggaga cggtgatcac    600

tgtggacact aaggcggcag gcaaaggcaa agtgacgtgc accgtgtgca cgcctgatgg    660

ctcagaggtg gatgtggacg tggtggagaa tgaggacggc actttcgaca tcttctacac    720

ggccccccag ccgggcaaat acgtcatctg tgtgcgcttt ggtggcgagc acgtgcccaa    780

cagccccttc caagtgacgg ctctggctgg ggaccagccc tcggtgcagc cccntctacg    840

gtctcagcag ctggccccac agtacaccta cgccccaggg gcggccagca nacttgggcc    900

cccggaaaag gcccctggtn gggtgtcaat gggctggatg tgacccagcc tgaggccctt    960

tgaccttgtc atcccnttca catcaanaan ggcnanatcc caggggaggt ttggaatgcc   1020

ntcaggcaag nngngcaccc nccnntcctt ganaanaaaa aggnaccgtg gaccgtgngg   1080

tntgccccaa cnaaggntgg cttgccnaaa antggaattn cnctnnnaaa aatngcaatn   1140

ccaagaaanc ccctttngnt ttttttngna taacctcant ngggcatttc ctggcn       1196


<210>  428
<211>  1719
<212>  DNA
<213>  Homo sapiens

<400>  428
atggagaccc cgtcccagcg gcgcgccacc cgcagcgggg cgcaggccag ctccactccg     60

ctgtcgccca cccgcatcac ccggctgcag gagaaggagg acctgcagga gctcaatgat    120

cgcttggcgg tctacatcga ccgtgtgcgc tcgctggaaa cggagaacgc agggctgcgc    180

cttcgcatca ccgagtctga agaggtggtc agccgcgagg tgtccggcat caaggccgcc    240

tacgaggccg agctcgggga tgcccgcaag acccttgact cagtagccaa ggagcgcgcc    300

cgcctgcagc tggagctgag caaagtgcgt gaggagttta aggagctgaa agcgcgcaat    360

accaagaagg agggtgacct gatagctgct caggctcggc tgaaggacct ggaggctctg    420

ctgaactcca aggaggccgc actgagcact gctctcagtg agaagcgcac gctggagggc    480

gagctgcatg atctgcgggg ccaggtggcc aagcttgagg cagccctagg tgaggccaag    540

aagcaacttc aggatgagat gctgcggcgg gtggatgctg agaacaggct gcagaccatg    600

aaggaggaac tggacttcca gaagaacatc tacagtgagg agctgcgtga gaccaagcgc    660

cgtcatgaga cccgactggt ggagattgac aatgggaagc agcgtgagtt tgagagccgg    720

ctggcggatg cgctgcagga actgcgggcc cagcatgagg accaggtgga gcagtataag    780

aaggagctgg agaagactta ttctgccaag ctggacaatg ccaggcagtc tgctgagagg    840

aacagcaacc tggtgggggc tgcccacgag gagctgcagc agtcgcgcat ccgcatcgac    900

agcctctctg cccagctcag ccagctccag aagcagctgg cagccaagga ggcgaagctt    960

cgagacctgg aggactcact ggcccgtgag cgggacacca gccggcggct gctggcggaa   1020

aaggagcggg agatggccga gatgcgggca aggatgcagc agcagctgga cgagtaccag   1080

gagcttctgg acatcaagct ggccctggac atggagatcc acgcctaccg caagctcttg   1140

gagggcgagg aggagaggct acgcctgtcc cccagcccta cctcgcagcg cagccgtggc   1200

cgtgcttcct ctcactcatc ccagacacag ggtgggggca gcgtcaccaa aaagcgcaaa   1260

ctggagtcca ctgagagccg cagcagcttc tcacagcacg cacgcactag cgggcgcgtg   1320

gccgtggagg aggtggatga ggagggcaag tttgtccggc tgcgcaacaa gtccaatgag   1380

gaccagtcca tgggcaattg gcagatcaag cgccagaatg gagatgatcc cttgctgact   1440

taccggttcc caccaaagtt caccctgaag gctgggcagg tggtgacgat ctgggctgca   1500

ggagctgggg ccacccacag cccccctacc gacctggtgt ggaaggcaca gaacacctgg   1560

ggctgcggga acagcctgcg tacggctctc atcaactcca ctggggaaga agtggccatg   1620

cgcaagctgg tgcgctcagt gactgtggtt gaggacgacg aggatgagga tggagatgac   1680

ctgctccatc accaccacgt gagtggtagc cgccgctga                          1719


<210>  429
<211>  519
<212>  DNA
<213>  Homo sapiens

<400>  429
cacgcgtccg ggtcaagcac accgggtggt gaaaaagaaa ccagcgcaac ccagcgtagc     60

agcgttccga gcagcaccga aaaaaatgca ctgagcaccg gtgttagctt ttttttcctg    120

agctttcata ttagcaacct gcagtttaat agcagcctgg aagatccgag caccgattat    180

tatcaagaac tgcagcgtga tatcagcgaa atgtttctgc agatctataa acagggtggt    240

tttctgggtc tgagcaacat caaatttcgt ccgggtagcg ttgttgttca gctgaccctg    300

gcatttcgtg aaggcaccat taatgttcat gatgtggaaa cccagtttaa ccagtataaa    360

accgaagcag caagccgtta taatctgacc attagtgatg ttagcgtttc cgatgttccg    420

tttccgttta gcgcacagag cggtgccggt gttccgggtt ggtaagcggc cgcggtacct    480

ggagcacaag actggcctca tgggccttcc gctcactgc                           519


<210>  430
<211>  1254
<212>  DNA
<213>  Homo sapiens

<400>  430
atgtcgcttt ctaacaagct gacgctggac aagctggacg ttaaagggaa gcgggtcgtt     60

atgagagtcg acttcaatgt tcctatgaag aacaaccaga taacaaacaa ccagaggatt    120

aaggctgctg tcccaagcat caaattctgc ttggacaatg gagccaagtc ggtagtcctt    180

atgagccacc taggccggcc tgatggtgtg cccatgcctg acaagtactc cttagagcca    240

gttgctgtag aactcaaatc tctgctgggc aaggatgttc tgttcttgaa ggactgtgta    300

ggcccagaag tggagaaagc ctgtgccaac ccagctgctg ggtctgtcat cctgctggag    360

aacctccgct ttcatgtgga ggaagaaggg aagggaaaag atgcttctgg gaacaaggtt    420

aaagccgagc cagccaaaat agaagctttc cgagcttcac tttccaagct aggggatgtc    480

tatgtcaatg atgcttttgg cactgctcac agagcccaca gctccatggt aggagtcaat    540

ctgccacaga aggctggtgg gtttttgatg aagaaggagc tgaactactt tgcaaaggcc    600

ttggagagcc cagagcgacc cttcctggcc atcctgggcg gagctaaagt tgcagacaag    660

atccagctca tcaataatat gctggacaaa gtcaatgaga tgattattgg tggtggaatg    720

gcttttacct tccttaaggt gctcaacaac atggagattg gcacttctct gtttgatgaa    780

gagggagcca agattgtcaa agacctaatg tccaaagctg agaagaatgg tgtgaagatt    840

accttgcctg ttgactttgt cactgctgac aagtttgatg agaatgccaa gactggccaa    900

gccactgtgg cttctggcat acctgctggc tggatgggct tggactgtgg tcctgaaagc    960

agcaagaagt atgctgaggc tgtcactcgg gctaagcaga ttgtgtggaa tggtcctgtg   1020

ggggtatttg aatgggaagc ttttgcccgg ggaaccaaag ctctcatgga tgaggtggtg   1080

aaagccactt ctaggggctg catcaccatc ataggtggtg gagacactgc cacttgctgt   1140

gccaaatgga acacggagga taaagtcagc catgtgagca ctgggggtgg tgccagtttg   1200

gagctcctgg aaggtaaagt ccttcctggg gtggatgctc tcagcaatat ttag         1254


<210>  431
<211>  866
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (792)..(792)
<223>  n is a, c, g, or t

<400>  431
tgtaattaag agatacttga gaggatgcat cccatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgact ctggaccttg gctgtcactc agttaagaac ctgaagaaga    120

attactgtcg taaccccgat agggagctgc ggccttggtg tttcaccacc gaccccaaca    180

agcgctggga actttgcgac atcccccgct gcacaacacc tccaccatct tctggtccca    240

cctaccagtg tctgaaggga acaggtgaaa actatcgcgg gaatgtggct gttaccgtgt    300

ccgggcacac ctgtcagcac tggagtgcac agacccctca cacacataac aggacaccag    360

aaaactttcc ctgcaaaaat ttggatgaaa actactgccg caatcctgac ggaaaaaggg    420

ccccatggtg ccatacaacc aacagccaag tgcggtggga gtactgtaag ataccgtcct    480

gtgactcctc cccagtatcc acggaacaat tggctcccac agcaccacct gagctaaccc    540

ctgtggtcca ggactgctac catggtgatg gacagagcta ccgaggcaca tcctccacca    600

ccaccacagg aaagaagtgt cagtcttggt catctatgac accacaccgg caccagaaga    660

ccccagaaaa ctacccaaat gctggcctga caatgaacta ctgcaggaat ccagatgccc    720

gataaggccc ctggtgtttt accacagacc ccagcgtcag gtgggagtac tgcaacctga    780

aaaaatgctc angaacagaa gcgaagtgtg tagccactcc gcctggtgtc ctggctccag    840

atgtaaagac tctttccgag aagact                                         866


<210>  432
<211>  916
<212>  DNA
<213>  Homo sapiens

<400>  432
tgagaggatc gcatcaccat caccatcacg gatcctattt aggtgacact atagaatcgt     60

cgacccacgc gtccgagacc ttctcctctt cctcctcatc caagaagatg ggcagcatct    120

tcgaccgcga ggaccaggcc agcccacggg ccggcagcct ggcggcgctc gagaaacggc    180

aggccgagaa gaagaaagag ctgatgaagg cgcagagtct gcccaagacc tcagcctccc    240

aggcgcgcaa ggccatgatt gagaagctgg agaaggaggg cgcggccggc agccctggcg    300

gaccccgcgc agccgtgcag cgatccacca gcttcggggt ccccaacgcc aacagcatca    360

agcagatgct gctggactgg tgtcgagcca agactcgcgg ctacgagcac gtcgacatcc    420

agaacttctc ctccagctgg agtgatggga tggccttctg tgccctggtg cacaacttct    480

tccctgaggc cttcgactat gggcagctta gccctcagaa ccgacgccag aacttcgagg    540

tggccttctc atctgcggag acccatgcgg actgcccgca gctcctggat acagaggaca    600

tggtgcggct tcgagagcct gactggaagt gcgtgtacac gtacatccag gaattctacc    660

gctgtctggt ccagaagggg ctggtaaaaa ccaaaaagtc ctaacccctg ctcggggccc    720

cacggatgct ggtggactgt gtgcccctgg tggaggtgga cgacatgatg atcatgggca    780

agaagcctga ccccaagtgt gtcttcacct atgtgcagtc gctctacaac cacctgcgac    840

gccacgaact gcgcctgcgc ggcaagaatg tctagcctgc ccgcccgcat ggccagccag    900

tggcaagctg ccgccc                                                    916


<210>  433
<211>  993
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (749)..(749)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (801)..(801)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (816)..(816)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (835)..(835)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (841)..(841)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (847)..(847)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (850)..(850)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (866)..(866)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (875)..(875)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (898)..(898)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (918)..(918)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (921)..(921)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (923)..(924)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (926)..(926)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (928)..(928)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (937)..(937)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (947)..(947)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (951)..(951)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (958)..(959)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (961)..(961)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (991)..(993)
<223>  n is a, c, g, or t

<400>  433
aatagagaaa ttactatgag aggatcgcat caccatcacc atcacgggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cgcttcctca ttaagagctt caatgacttc    120

aactcctccc cctccagtac ctcccccacc tccacctcca gccactgctt tgcaagctcc    180

agcagtacca ccacctccag ctcctcttca gattgcccct ggagttcttc acccagctcc    240

tcctccaatt gcacctcctc tagtacagcc ctctccacca gtagctagag ctgccccagt    300

atgtgagact gtaccagttc atccactccc acaaggtgaa gttcaggggc tgcctccacc    360

cccaccaccg cctcctctgc ctccacctgg cattcgacca tcatcacctg tcacagttac    420

agctcttgct catcctccct ctgggctaca tccaactcca tctactgccc caggtcccca    480

tgttccatta atgcctccat ctcctccatc acaagttata cctgcttctg agccaaagcg    540

ccatccatca accctacctg taatcagtga tgccaggagt gtgctactgg aagcaatacg    600

aaaaggtatt cagctacgca aagtagaaga gcagcgtgaa caggaagcta agcatgaacg    660

cattgaaaac gatgttgcca ccatcctgtc tcgccgtatt gctgttgaat atagtgattc    720

ggaagatgat tcagaatttg atgaagtana ttggttggag taagaaaaaa tgcattgata    780

aatattacaa aactgaatgc naatgtcctt tgtggngctt gttccttgaa aatgnttggg    840

ncattcnagn gttttgcttt cttttncctt ataanaaatg acccttttcc tccataantt    900

ttgatttcta aggaaaanat nannananat ttcaaantaa aggtttnaaa nggggntnnc    960

nttttttttc ccctgaaaag antaatttgg nnn                                 993


<210>  434
<211>  816
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (728)..(728)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (786)..(786)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (795)..(795)
<223>  n is a, c, g, or t

<400>  434
tnanaggaga attaactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgctaggat cgcgacggga actggagccc    120

gaggtccccg cgcggcccgg gcctggcgcc ctgaggggaa gagcggcccg gcccgagcca    180

tgacggacgg gatcctaggg aaggcagcca caatggagat ccctatccac gggaacggcg    240

aagccaggca gcttcctgaa gatgatgggc tggagcagga cctccagcag gtgatggtgt    300

caggacccaa cctcaatgaa accagcattg tgtctggtgg ctatgggggc tctggtgatg    360

gactcatccc cacagggtct ggccgccatc catctcacag caccactcct tctggccctg    420

gagatgaggt ggctcggggc attgctggag aaaagtttga catcgtcaag aaatggggca    480

tcaacaccta taagtgcaca aagcaactgt tatcagaacg atttggtcga ggctcacgga    540

ctgtggacct ggagctagag ctgcagattg agttgctgcg tgagacgaag cgcaagtatg    600

agagtgtcct gcagctgggc cgggcactga cagcccacct ctacagcctg ctgcagaccc    660

agcatgcact gggtgatgcc tttgctgacc tcagccagaa gtccccagag cttcaggagg    720

aatttggnct acaatgcaga gacacagaaa actactatgc aagaatgggg gaaacgctgc    780

tagganccgt gaacntcttt gtctctagca tcaaac                              816


<210>  435
<211>  950
<212>  DNA
<213>  Homo sapiens

<400>  435
atgagaggtc gcatcaccat caccatcacg gatcctattt aggtgacact atagaatcgt     60

cgacccacgc gtccgcacag cccctgctgg gacaacagag acttgagcac agcagcttcc    120

ccgaagggcc gggacctggc tcaggggacg aagccaatgg gccccgggga gagaggcaga    180

cccggactcg gggcccggcc ccatctgcaa tgccccagag caggtctacc gagtcagccc    240

atgctgccac cctgccgcct cgaggcccag agccatctgc ccaggagcag atggagggga    300

tgctgtgccg caagcaggag atggaggcct tcgggaagaa ggctgccaac aggtcctggc    360

agaacgtgta ctgtgtcctg cggcgtggga gcctcgactt ttacaaggat gccaaggcag    420

ccagcgcggg agtgccatac cacggagaag tgcctgtcag cctggccagg gcccagggca    480

gcgtcgcctt tgattaccga aagcgcaaac atgtcttcaa gctgggctta caggatggaa    540

aagaatattt attccaggcc aaggatgagg cagagatgag ctcgtggcta cgggtggtga    600

atgcagccat tgccacagcg tcttctgcct ctggagagcc tgaagagccg gtggtgccca    660

gcaccacccg gggcatgacc cgggccatga ccatgccccc agtgtcaccc gtcggggctg    720

aggggcctgt tgtgctccgc agcaaagacg gcagagaacg agagcgagaa aaacgcttca    780

gcttctttaa gaagaacaag tagttggggg caaggtccca ggccaactcc ctccctccgt    840

tcaggaaact gccagggaca gtcgacaggg accgccctct tgtcaggaca actgcctgct    900

gctagggtct gttgccaagg tcaacccatc accaggaact gtcactgggg               950


<210>  436
<211>  1515
<212>  DNA
<213>  Homo sapiens

<400>  436
atggttctag cagaccttgg aagaaaaata acatcagcat tacgctcgtt gagcaatgcc     60

accattatca atgaagaggt attgaatgct atgctaaaag aagtctgtac cgctttgttg    120

gaagcagatg ttaatattaa actagtgaag caactaagag aaaatgttaa gtctgctatt    180

gatcttgaag agatggcatc tggtcttaac aaaagaaaaa tgattcagca tgctgtattt    240

aaagaacttg tgaagcttgt agaccctgga gttaaggcat ggacacccac taaaggaaaa    300

caaaatgtga ttatgtttgt tggattgcaa gggagtggta aaacaacaac atgttcaaag    360

ctagcatatt attaccagag gaaaggttgg aagacctgtt taatatgtgc agacacattc    420

agagcagggg cttttgacca actaaaacag aatgctacca aagcaagaat tccattttat    480

ggaagctata cagaaatgga tcctgtcatc attgcttctg aaggagtaga gaaatttaaa    540

aatgaaaatt ttgaaattat tattgttgat acaagtggcc gccacaaaca agaagactct    600

ttgtttgaag aaatgcttca agttgctaat gctatacaac ctgataacat tgtttatgtg    660

atggatgcct ccattgggca ggcttgtgaa gcccaggcta aggcttttaa agataaagta    720

gatgtagcct cagtaatagt gacaaaactt gatggccatg caaaaggagg tggtgcactc    780

agtgcagtcg ctgccacaaa aagtccgatt attttcattg gtacagggga acatatagat    840

gactttgaac ctttcaaaac acagcctttt attagcaaac ttcttggtat gggcgacatt    900

gaaggactga tagataaagt caacgagttg aagttggatg acaatgaagc acttatagag    960

aagttgaaac atggtcagtt tacgttgcga gacatgtatg agcaatttca aaatatcatg   1020

aaaatgggcc ccttcagtca gatcttgggg atgatccctg gttttgggac agattttatg   1080

agcaaaggaa atgaacagga gtcaatggca aggctaaaga aattaatgac aataatggat   1140

agtatgaatg atcaagaact agacagtacg gatggtgcca aagtttttag taaacaacca   1200

ggaagaatcc aaagagtagc aagaggatcg ggtgtatcaa caagagatgt tcaagaactt   1260

ttgacacaat ataccaagtt tgcacagatg gtaaaaaaga tgggaggtat caaaggactt   1320

ttcaaaggtg gcgacatgtc taagaatgtg agccagtcac agatggcaaa attgaaccaa   1380

caaatggcca aaatgatgga tcctagggtt cttcatcaca tgggtggtat ggcaggactt   1440

cagtcaatga tgaggcagtt tcaacagggt gctgctggca acatgaaagg catgatggga   1500

ttcaataata tgtaa                                                    1515


<210>  437
<211>  871
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (5)..(5)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (17)..(17)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (20)..(20)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (25)..(27)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (29)..(29)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (77)..(77)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (155)..(155)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (259)..(260)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (268)..(268)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (306)..(306)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (321)..(322)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (324)..(325)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (379)..(380)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (698)..(698)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (738)..(738)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (741)..(741)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (743)..(743)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (757)..(757)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (772)..(772)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (796)..(796)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (800)..(800)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (807)..(807)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (826)..(826)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (829)..(829)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (837)..(838)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (842)..(842)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (855)..(855)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (858)..(858)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (866)..(866)
<223>  n is a, c, g, or t

<400>  437
aaaancccaa ttnttanagn ggagnnntna ctctgagagg atcgcatcac catcaccatc     60

acggatccta tttaggngac actatagaat cgtcgaccca cgcgtccgat tttaaatcca    120

gctccataca acgctccgcc gccgctgctg ccgcnacccg gactgcgcgc cagcaccccc    180

ctgccgacag ctccgtcact atggaggata tgaacgagta cagcaatata gaggaattcg    240

cagagggatc caagatcann tttttttnga atcagcagga tgacggtaaa atgtttattg    300

gagggnggag ctgggataca nncnnaaaag atctgacaga gtacttgtct cgatttgggg    360

aagttgtaga ctgcacaann aaaacagatc cagtcactgg gagatcaaga ggatttggat    420

ttgtgctttt caaagatgct gctagtgttg ataaggtttt ggaactgaaa gaacacaaac    480

tggatggcaa attgatagat cccaaaaggg ccaaagcttt aaaagggaaa gaacctccca    540

aaaaggtttt tgtgggtgga ttgagcccgg atacttctga agaacaaatt aaagaatatt    600

ttggagcctt tggagagatt gaaaatattg aacttcccat gggtacaaaa acaaatgaaa    660

agaagaggat tttgttttat cacgtatact gatgaaanag ccagcaaaaa aaaatgttag    720

aaagcagata ccatcaantt ngnttctggg aaggggngaa atcaaagttg cncaccccaa    780

aaaggttttt taggcnggcn accagcnacc accaaaaagg gggaanagng gctgcanntg    840

gngggacaag ggggnccnag gggtcngggc c                                   871


<210>  438
<211>  1191
<212>  DNA
<213>  Homo sapiens

<400>  438
atgttcctga aggccgtggt cctgaccctg gccctggtgg ctgtcgccgg agccagggct     60

gaggtcagtg ctgaccaggt ggccacagtg atgtgggact acttcagcca gctgagcaac    120

aatgccaagg aggccgtgga acatctccag aaatctgaac tcacccagca actcaatgcc    180

ctcttccagg acaaacttgg ggaagtgaac acttacgcag gtgacctgca gaagaagctg    240

gtgccctttg ccaccgagct gcatgaacgc ctggccaagg actcggagaa actgaaggag    300

gagattggga aggagctgga ggagctgagg gcccggctgc tgccccatgc caatgaggtg    360

agccagaaga tcggggacaa cctgcgagag cttcagcagc gcctggagcc ctacgcggac    420

cagctgcgca cccaggtcaa cacgcaggcc gagcagctgc ggcgccagct gaccccctac    480

gcacagcgca tggagagagt gctgcgggag aacgccgaca gcctgcaggc ctcgctgagg    540

ccccacgccg acgagctcaa ggccaagatc gaccagaacg tggaggagct caagggacgc    600

cttacgccct acgctgacga attcaaagtc aagattgacc agaccgtgga ggagctgcgc    660

cgcagcctgg ctccctatgc tcaggacacg caggagaagc tcaaccacca gcttgagggc    720

ctgaccttcc agatgaagaa gaacgccgag gagctcaagg ccaggatctc ggccagtgcc    780

gaggagctgc ggcagaggct ggcgcccttg gccgaggacg tgcgtggcaa cctgaggggc    840

aacaccgagg ggctgcagaa gtcactggca gagctgggtg ggcacctgga ccagcaggtg    900

gaggagttcc gacgccgggt ggagccctac ggggaaaact tcaacaaagc cctggtgcag    960

cagatggaac agctcaggca gaaactgggc ccccatgcgg gggacgtgga aggccacttg   1020

agcttcctgg agaaggacct gagggacaag gtcaactcct tcttcagcac cttcaaggag   1080

aaagagagcc aggacaagac tctctccctc cctgagctgg agcaacagca ggaacagcag   1140

caggagcagc agcaggagca ggtgcagatg ctggcccctt tggagagctg a            1191


<210>  439
<211>  1085
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (344)..(344)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (474)..(474)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (525)..(525)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (566)..(566)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (642)..(642)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (750)..(750)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (805)..(805)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (814)..(814)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (861)..(861)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (893)..(893)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (896)..(896)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (913)..(913)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (924)..(924)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (927)..(928)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (938)..(938)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (952)..(952)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (954)..(954)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (961)..(961)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (963)..(963)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (998)..(998)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1007)..(1007)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1016)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1019)..(1019)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1027)..(1030)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1032)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1042)..(1042)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1051)..(1051)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1060)..(1060)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1074)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1076)..(1076)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1078)..(1080)
<223>  n is a, c, g, or t

<400>  439
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgttccg cccacgcgtc cgcccacgcg ttccgcgccg    120

gcggttgcct cgcggggttg cggcgagccc ggcccgcgaa cgtcacgtcc ctgcgcgctc    180

cctgcactct cccgagctgc gctaggcggg cgccacggct gcccggcgaa ggaaaccgaa    240

accgagtccg ggcccgtccc tccgcggccc catccgcccg gtgcacccgg ggtcgcgctc    300

gccaggccgc ggagcccaga gctgcgcgca cgaaccgtgc gccnggaggg cgtgggcgtg    360

gcgccgaagg gtcccgggtc ttcgacgcct ctgcggcggc tcctccctcc ttgcagttgg    420

atccctggcg ggtgcggccc ggcccggccc gtgagcggcg cacagaatgg gccnatgctg    480

cttctacacg gcggggacgt tgtccctgct cctgctggtg accancgtca cgctgctggt    540

ggcccgggtc ttccagaagg ctgtanacca gagtatcgag aagaaaattg tgttaaggaa    600

tggtactgag gcatttgact cctgggagaa gccccctctg cntgtgtata ctcagttcta    660

tttcttcaat gtcaccaatc cagaggagat cctcagaggg gagacccctc gggtggaaaa    720

aatggggcca tacacctaca gggaactcan aaacaaagca aatattcaat ttggagataa    780

tggaacaaca atatctgctg ttaanaacaa aggnctatgt ttttgaacga aaaccaatct    840

gtttggaaaa ccctaaaatt naactttaat taaaaaattt aaataattcc tgnaantgac    900

ttgtcaaaaa aantgggtcc caangtnnac tttcctcnag ggaaaatcat cnanggccca    960

ntntttaaaa agccttatta ancaaaaaac tttttttntg aaatcanaac aagttnaana   1020

aaatttnnnn tnttgggggc tnaaaaaaaa naaaaaattn ttgtcccctt taancnannn   1080

ttttt                                                               1085


<210>  440
<211>  921
<212>  DNA
<213>  Homo sapiens

<400>  440
atggccagca acgttaccaa caagacagat cctcgctcca tgaactcccg tgtattcatt     60

gggaatctca acactcttgt ggtcaagaaa tctgatgtgg aggcaatctt ttcgaagtat    120

ggcaaaattg tgggctgctc tgttcataag ggctttgcct tcgttcagta tgttaatgag    180

agaaatgccc gggctgctgt agcaggagag gatggcagaa tgattgctgg ccaggtttta    240

gatattaacc tggctgcaga gccaaaagtg aaccgaggaa aagcaggtgt gaaacgatct    300

gcagcggaga tgtacgggtc agtaacagaa cacccttctc cgtcccctct actcagctcc    360

tcttttgact tggactatga ctttcaacgg gactattatg ataggatgta cagttaccca    420

gcacgtgtac ctcctcctcc tcctattgct cgggctgtag tgccctcgaa acgtcagcgt    480

gtatcaggaa acacttcacg aaggggcaaa agtggcttca attctaagag tggacagcgg    540

ggatcttcca agtctggaaa gttgaaagga gatgaccttc aggccattaa gaaggagctg    600

acccagataa aacaaaaagt ggattctctc ctggaaaacc tggaaaaaat tgaaaaggaa    660

cagagcaaac aagcagtaga gatgaagaat gataagtcag aagaggagca gagcagcagc    720

tccgtgaaga aagatgagac taatgtgaag atggagtctg gggggggtgc agatgactct    780

gctgaggagg gggacctact ggatgatgat gataatgaag atcgggggga tgaccagctg    840

gagttgatca aggatgatga aaaagaggct gaggaaggag aggatgacag agacagcgcc    900

aatggcgagg atgactctta a                                              921


<210>  441
<211>  1248
<212>  DNA
<213>  Homo sapiens

<400>  441
atgatgctgg gccctgaggg aggtgaaggc tttgtggtca agctccgtgg cctgccctgg     60

tcctgctctg ttgaggacgt gcagaacttc ctctctgact gcacgattca tgatggggcc    120

gcaggtgtcc atttcatcta cactagagag ggcaggcaga gtggtgaggc ttttgttgaa    180

cttggatcag aagatgatgt aaaaatggcc ctgaaaaaag acagggaaag catgggacac    240

cggtacattg aggtgttcag gtcccacaga accgagatgg attgggtgtt gaagcacagt    300

ggtcccaaca gtgccgacag cgccaacgat ggcttcgtgc ggcttcgagg actcccattt    360

ggatgcacaa aggaagaaat tgttcagttc ttctcagggt tggaaattgt gccaaacggg    420

atcacattgc ctgtggaccc cgaaggcaag attacagggg aagcgttcgt gcagtttgcc    480

tcgcaggagt tagctgagaa ggctctaggg aaacacaagg agaggatagg gcacaggtac    540

attgaggtgt ttaagagcag ccaggaggaa gttaggtcat actcagatcc ccctctgaag    600

ttcatgtccg tgcagcggcc agggccctat gaccggcccg ggactgccag gaggtacatt    660

ggcatcgtga agcaggcagg cctggaaagg atgaggcctg gtgcctacag cacaggctac    720

gggggctacg aggagtacag tggcctcagt gatggctacg gcttcaccac cgacctgttc    780

gggagagacc tcagctactg tctctccgga atgtatgacc acagatacgg cgacagtgag    840

ttcacagtgc agagcaccac aggccactgt gtccacatga ggggcctgcc gtacaaagcg    900

accgagaacg acatttacaa cttcttctct cctctcaacc ctgtgagagt ccatattgag    960

attggcccag atggaagagt gacgggtgaa gcagatgttg agtttgctac tcatgaagaa   1020

gctgtggcag ctatgtccaa agacagggcc aatatgcagc acagatatat agaactcttc   1080

ttgaattcaa caacaggggc cagcaatggg gcgtatagca gccaggtgat gcaaggcatg   1140

ggggtgtctg ctgcccaggc cacttacagt ggcctggaga gccagtcagt gagtggctgt   1200

tacggggccg gctacagtgg gcagaacagc atgggtggct atgactag                1248


<210>  442
<211>  1203
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (649)..(649)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (809)..(809)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (901)..(901)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (952)..(952)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (960)..(961)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (965)..(965)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (967)..(967)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (970)..(970)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (990)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (999)..(999)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1012)..(1012)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1025)..(1025)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1032)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1039)..(1039)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1060)..(1060)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1097)..(1097)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1107)..(1107)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1125)..(1125)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1132)..(1132)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1136)..(1136)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1139)..(1139)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1144)..(1144)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1163)..(1163)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1176)..(1176)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1179)..(1179)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1183)..(1183)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1187)..(1187)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1189)..(1189)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1196)..(1196)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1200)..(1200)
<223>  n is a, c, g, or t

<400>  442
tagagaaaat tactatgaga ggatcgcatc accatcacca tcacggaatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gtaggagaag tgattcttgt gggtggcatg    120

actaggatgc ccaaggttca gcagactgta caggatcttt ttggcagagc cccaagtaaa    180

gctgtcaatc ctgatgaggc tgtggccatt ggagctgcca ttcagggagg tgtgttggcc    240

ggcgatgtca cggatgtgct gctccttgat gtcactcccc tgtctctggg tattgaaact    300

ctaggaggtg tctttaccaa acttattaat aggaatacca ctattccaac caagaagagc    360

caggtattct ctactgccgc tgatggtcaa acgcaagtgg aaattaaagt gtgtcagggt    420

gaaagagaga tggctggaga caacaaactc cttggacagt ttactttgat tggaattcca    480

ccagcccctc gtggagttcc tcagattgaa gttacatttg acattgatgc caatgggata    540

gtacatgttt ctgctaaaga taaaggcaca ggacgtgagc agcagattgt aatccagtct    600

tctggtggat taagcaaaga tgatattgaa aatatggtta aaaatgcana gaaatatgct    660

gaagaagacc ggcgaaagaa ggaacgagtt gaagcagtta atatggctga aggaatcatt    720

cacgacacag aaaccaagat ggaagaattc aaggaccaat tacctgctga tgagtgcaac    780

aagctgaaag aagagatttc caaaatgang gagctcctgg ctagaaaaga cagcgaaaca    840

ggagaaaata ttagacaggc agcatcctct cttcagcagg catcactgaa gctgttcgaa    900

ntggcataca aaaagatggc atctgaacga gaaggctctg gaagttctgg cnctggggan    960

naaangnaan atcaaaagga ggaaaaacgn tataaatanc aaaattttga ancccgaagg   1020

acacntatga anctaggant gaaaaactcc tgaacaaaan ggggaacttc agccttttac   1080

ggggttttgc agaatcnaaa aaaattncct aattggaaat taggncctta cnaggntcnt   1140

ttanggacag ggattccaaa ganaagtcaa aatttngtnc ccnccgncnt tttccngcgn   1200

gaa                                                                 1203


<210>  443
<211>  588
<212>  DNA
<213>  Homo sapiens

<400>  443
atggccctcc tgttccctct actggcagcc ctagtgatga ccagctatag ccctgttgga     60

tctctgggct gtgatctgcc tcagaaccat ggcctactta gcaggaacac cttggtgctt    120

ctgcaccaaa tgaggagaat ctcccctttc ttgtgtctca aggacagaag agacttcagg    180

ttcccccagg agatggtaaa agggagccag ttgcagaagg cccatgtcat gtctgtcctc    240

catgagatgc tgcagcagat cttcagcctc ttccacacag agcgctcctc tgctgcctgg    300

aacatgaccc tcctagacca actccacact ggacttcatc agcaactgca acacctggag    360

acctgcttgc tgcaggtagt gggagaagga gaatctgctg gggcaattag cagccctgca    420

ctgaccttga ggaggtactt ccagggaatc cgtgtctacc tgaaagagaa gaaatacagc    480

gactgtgcct gggaagttgt cagaatggaa atcatgaaat ccttgttctt atcaacaaac    540

atgcaagaaa gactgagaag taaagataga gacctgggct catcttga                 588


<210>  444
<211>  1100
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (855)..(855)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (972)..(972)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (996)..(996)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (998)..(998)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1016)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1022)..(1022)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1024)..(1024)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1027)..(1027)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1037)..(1037)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1063)..(1063)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1084)..(1084)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1087)..(1087)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1094)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1100)..(1100)
<223>  n is a, c, g, or t

<400>  444
agagaaatta ctatgagagg atcgcatcac catcaccatc acggatccta tttaggtgac     60

actatagaat cgtcgaccca cgcgtccgtg aaagccacag atcaggaaaa gagcagaaaa    120

ctacatgaac ttacggttat gcaagataga cgagaacaag caagacaaga cttgaagggt    180

ttggaagaga cagtggcaaa agaacttcag actttacaca acctgcgcaa actctttgtt    240

caggacctgg ctacaagagt taaaaagagt gctgagattg attctgatga caccggaggc    300

agcgctgctc agaagcaaaa aatctccttt cttgaaaata atcttgaaca gctcactaaa    360

gtgcacaaac agttggtacg tgataatgca gatctccgct gtgaacttcc taagttggaa    420

aagcgacttc gagctacagc tgagagagtg aaagctttgg aatcagcact gaaagaagct    480

aaagaaaatg catctcgtga tcgcaaacgc tatcagcaag aagtagatcg cataaaggaa    540

gcagtcaggt caaagaatat ggccagaaga gggcattctg cacagattgc taaacctatt    600

cgtcccgggc aacatccagc agcttctcca actcacccaa gtgcaattcg tggaggaggt    660

gcatttgttc agaacagcca gccagtggca gtgcgaggtg gaggaggcaa acaagtgtaa    720

tcgtttatac atacccacag gtgttaaaaa gtaatcgaag tacgaagagg acatggtatc    780

aagcagtcat tcaatgacta taacctctac tcccttggga ttgtagaatt ataactttta    840

aaaaaaatgt ataanttata cctggcctgt acagctgttt cctacctact cttcttgtaa    900

actctgctgc ttcccaacac aactagagtg cattttggca tcttaggagg gaaaaggaca    960

gtttacaact gnggccctat ttattaccca gtttgncnat cgggcctaaa tttagnctta   1020

cngngcnagc tactgtncct aaaggacgga cttttggatt ttngggaggt tatttttaac   1080

cccnttnaat accnaccgcn                                               1100


<210>  445
<211>  1169
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (922)..(922)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (933)..(933)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (955)..(955)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (961)..(961)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1003)..(1003)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1012)..(1012)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1022)..(1022)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1030)..(1030)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1032)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1053)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1075)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1084)..(1084)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1088)..(1088)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1108)..(1108)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1111)..(1111)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1126)..(1128)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1131)..(1132)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1138)..(1138)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1142)..(1142)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1145)..(1145)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1148)..(1148)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1162)..(1163)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1165)..(1165)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1168)..(1168)
<223>  n is a, c, g, or t

<400>  445
tagagaaaat tactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg ggcccttgct catcaccttc accccagcca    120

ctgaccccag cgacctctgg aaggatgggc agcagcagcc acagcccgag aagccagagt    180

ccaccctgga tggggctgca gccctagctt tctatgaggc cctgattggg gatgagagca    240

gcgctcctga ctcccagaga tctcagactg aacctgccag agaaagaaag agaaagaaaa    300

gaagaataat gaaggcacca gcagcagaag cagtggcaga aggagcatca ggaagacatg    360

gacaagggag atcccttgag gctgaggata agatgactca ccggatactg agggcagccc    420

aggaggggga cctgccagaa cttaggagac tgctggaacc gcatgaggca ggaggagctg    480

gggggaatat caacgcccgg gatgccttct ggtggacccc actgatgtgt gctgctcgag    540

cgggccaggg ggcagctgtg agctatctcc tgggccgtgg ggctgcctgg gtgggggtct    600

gtgagctgag tggcagggat gcggctcagc tcgctgaaga agctggcttc cctgaggtag    660

cccgcatggt cagggagagc catggagaga caaggagccc ggaaaaccgg tctcctactc    720

cctccctcca gtactgtgag aactgtgaca cccacttcca agattccaac caccgcacat    780

ccactgctca cctgctgtca ctgtcgcagg gtcctcaccc tcccaacctt ccacttgggg    840

tgcccatctc cagcccgggc ttcaactgct gctgaagggg gggctgggaa ccagaatggg    900

ggctgggaac cccgggggtg anggccgtgc cantcccatc cccactgtcc tcaanaggga    960

nccaggaaag aactaggcta cngatcaccc cccccanccc ccnantgaaa cntttttccc   1020

ancttgggan ancccaaact tgtggctggg aanggaaaaa accccccctc gggnnggccc   1080

cccntganct tggagggnag naaaaaanga nggaaagaaa aaaaannngg nnttgggnaa   1140

cnggnttnta aggactttac tnnanccnc                                     1169


<210>  446
<211>  623
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (623)..(623)
<223>  n is a, c, g, or t

<400>  446
tagagagata ctatgagagg acgcatcacc atcaccatca cggatcctat ttaggtgaca     60

ctatagaatc gtcgactctg gaccttggct gtcactcagt tatcactgtc atgtctggtc    120

gtggcaagca aggaggcaag gcccgcgcca aggccaagtc gcgctcgtcc cgcgctggcc    180

ttcagttccc ggtagggcga gtgcatcgct tgctgcgcaa aggcagctac gcggagcgag    240

tgggggccgg cgcgcccgtc tacatggctg cggtcctcga gtatctgacc gccgagatcc    300

tggagctggc gggcaacgcg gctcgggaca acaagaagac gcgcatcatc cctcgtcacc    360

tccagctggc catccgcaac gacgaggaac tgaacaagct gctgggcaaa gtcaccatcg    420

cccagggcgg cgtcttgcct aacatccagg ccgtactgct ccctaagaag acggagagtc    480

accacaaggc aaagggcaag tgaggctgac gtccggccca agtgggccca gcccggcccg    540

cgtctcgaag gggcacctgt gaactcaaaa ggctcttttc agagccaccc acgttttcaa    600

ataaaagagt tgttaatgct gan                                            623


<210>  447
<211>  1179
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (479)..(479)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (944)..(944)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (985)..(985)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (992)..(992)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1015)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1051)..(1051)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1054)..(1054)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1056)..(1056)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1066)..(1066)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1074)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1094)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1100)..(1100)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1107)..(1107)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1116)..(1116)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1121)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1128)..(1128)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1132)..(1132)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1145)..(1145)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1150)..(1150)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1153)..(1153)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1169)..(1169)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1172)..(1172)
<223>  n is a, c, g, or t

<400>  447
anaatngaga aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgcggacgc gtgggtggcg gctgggctgc    120

ggaaacgcgg ccggtccggt tccgcggccc aggcagaggg actctgcaag caatggctgc    180

agcgcgcctg gcaagagcgg cgcctgctgc tgcgggagcc gcgctacacg ctgctggtgg    240

ccgcctgcct ctgcctggcg gaggtgggca tcaccttctg ggtcattcac agggtggcat    300

acacagagat tgactggaag gcctacatgg ccgaggtaga aggcgtcatc aatggtacct    360

atgactatac ccaactgcag ggtgacaccg gaccacttgt gtacccagct ggtttcgtgt    420

acatctttat ggggttgtac tatgccacca gccgaggcac tgacatccgc atggcccana    480

acatctttgc tgtgctctac ctggctacct tgctgcttgt cttcttgatc tatcaccaga    540

cctgcaaggt acctcccttc gtctttttct tcatgtgctg cgcctcttac cgtgtccact    600

ccatctttgt gctgcggctc ttcaatgacc cagtggccat ggtgctgctc ttcctcagta    660

tcaacctcct gctggcccag cgctggggct ggggttgctg ctttttcagc ctggcagtct    720

ctgtgaagat gaatgtgctg ctcttcgccc ctgggttact gtttcttctc ctcacacagt    780

ttggcttccg tggggccctc cccaagctgg gaatctgtgc tggccttcag gtggtgctgg    840

ggctgccctt cctgctggag aaccccagcg gctacctgtc ccgctccttt gaccttggcc    900

gccagtttct gttccactgg acagtgaact ggcgctttcc tccnaaaggc gctctttctg    960

catcgagcct tccacctggc cctgntgact gnccacctca ccctgctcct gctgntttgc   1020

cctctgcagg tggcacagga aaggggaaaa nttntngtcc ctgctnaagg aatncctcca   1080

aaaggaaggt tccnccccan ccccttnaan cccaanccat nttccttnaa antttgggga   1140

aaggnaaatn ttngccctcc tctaagggnc tnaaaaaaa                          1179


<210>  448
<211>  1293
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  n is a, c, g, or t

<400>  448
nccgcccctt cgnctaagaa ttactagaga ggacgcatca ccatcaccat cacggtcgac     60

ccacgcgtcc ggacagcccc tcgcctggct cctcactgcc atcacccctg agtgacccac    120

gccgggagcc catgaacatc tacaacctga tcgctatcat ccgtgaccag atcaagcacc    180

tgcaggcagc cgtggaccgc accacggagc tgtcacgcca gcgcattgcc tctcaggagc    240

tgggccccgc cgtggacaag gacaaggaag cgcttatgga ggagatcctc aagctgaagt    300

cgctgctcag caccaagcgg gagcagatca ccacgctgcg cactgtgctc aaggccaaca    360

agcagacggc cgaggtggcc cttgccaacc tgaagagcaa gtatgagaat gagaaggcca    420

tggttaccga gaccatgatg aagctgcgca atgagctcaa ggccctcaag gaggacgcag    480

ccaccttctc ctcgctgcgt gctatgtttg ccaccaggtg tgacgagtac attacacagc    540

tggatgagat gcagcggcag ctggcggctg ctgaggacga gaagaagacg ctgaactcgc    600

tgctgcgcat ggccatccag cagaagctgg cgctgaccca gcggctggag ctgctcgagc    660

tggaccatga gcagacccgg cgtggccgtg ccaaagccgc cccgaagacc aagccagcca    720

caccgagcct gtagagtagc tgccaggagg acttggccac ccggccctgt cacactgcag    780

ccccttcccc ttccctctcg tggcccacaa ggaggaagga agggcaacct aaaagcccac    840

ttagaaactt tttggatatg ccactgcaat tcttttcaaa atagcattcc cccagttttt    900

tatgggagga aaaaaagctt taatggtgag catgctgcga gctgctgcgt ggaaaggcct    960

ctgtatgggc cgaagaccct ttctccctgg ctgccaggct cgccaggagc ccactgggaa   1020

cgcccaacac gggggctcct gttacacatg gtcttttttt atccgatcaa cctgtgcact   1080

tttgaaattt gaaataaatt tgcttcccct aatccccgcg aaaagacggc tccggtgccg   1140

gggccaatgc tccgggccct gaacttggcg cctcacctcc ccccggtttt tctgggggca   1200

cccccaagca aaaaatgtgg gccccaaagg gggagcctta aaccccaaaa aaggggcttt   1260

ccccccgagg ggccccctaa tggtttcccc ctg                                1293


<210>  449
<211>  1403
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (13)..(15)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (873)..(873)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(957)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (993)..(993)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (998)..(999)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1003)..(1003)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1012)..(1015)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1027)..(1032)
<223>  n is a, c, g, or t

<400>  449
nncgactatc gtnnnccaag agatactata gaggatgcat caccatcacc atcacggtcg     60

acccacgcgt ccgcccacgc gtccggagaa gatgacagtt caactagaag agactggtaa    120

gagattgcag tttgcagaaa gcagaggtcc acagcttgaa ggtgctgaca gtaagagctg    180

gaaatccatt gtggttacaa gaatgtatga aaccaagtta aaagaattgg aaactgatat    240

tgccaaaaaa aatcaaagca ttactgacct taaacagctt gtaaaagaag caacagagag    300

agaacaaaaa gttaacaaat acaatgaaga ccttgaacaa cagattaaga ttcttaaaca    360

tgttcctgaa ggtgctgaga cagagcaagg ccttaaacgg gagcttcaag ttcttagatt    420

agctaatcat cagctggata aagagaaagc agaattaatc catcagatag aagctaacaa    480

ggaccaaagt ggagctgaaa gcaccatacc tgatgctgat caactaaagg aaaaaataaa    540

agatctagag acacagctca aaatgtcaga tctagaaaag cagcatttga aggaggaaat    600

aaagaagctg aaaaaagaac tggaaaattt tgatccttca ttttttgaag aaattgaaga    660

tcttaagtat aattacaagg aagaagtgaa gaagaatatt ctcttagaag agaaggtaaa    720

aaaactttca gaacaattgg gagttgaatt aactagccct gttgctgctt ctgaagagtt    780

tgaagatgaa gaagaaagtc ctgttaattt ccccatttac taaaggtcac ctataaactt    840

tgtttcattt aactatttat taactttata agntaaatat acttggaaat aagcagttct    900

ccgaactgta gtatttcctt ctcactacct tgtaccttta tacttagatt gaattnncta    960

ataaataaaa ttatatgaaa ttttcaaaaa aanaaaanna aanaaaaaaa annnnaaaaa   1020

aaaaaannnn nnaagggggg ccgctgcaag acctcgcgcc gactcgcgac ggagaacgct   1080

tgcacgccag aaagtccctc tatggctgct gaacggctct gaaccaacaa cccccctcgg   1140

ctcggaacaa atcccaaaac gaaaggagtg aatggcaaac catgatgccc tgaacacggg   1200

gcttccccaa gaacaagggt tgccctcccc gccccccggg gggtggggaa ttcccacccc   1260

tccacccaaa aaaaccccac gcttcacgcc taggggaaca tacaacgggg gaaaaattcc   1320

cacccttttt tttggtgccc catttaaaac cccccccctc ctccccccat taaaaccata   1380

ttcccccgct acggagacct tca                                           1403


<210>  450
<211>  846
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (811)..(811)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (837)..(837)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (845)..(845)
<223>  n is a, c, g, or t

<400>  450
tnagaggaga aattaactat gagaggatcg catcaccatc accatcacgg atcctattta     60

ggtgacacta tagaatcgtc gacccacgcg tccggcgccg gctccagggc catgaagccc    120

ccaggaggag aatcgagcaa tctttttgga agtccagaag aagctactcc ttccagcagg    180

cctaatagga tggcatctaa tatttttgga ccaacagaag aacctcagaa catacccaag    240

aggacaaatc ccccaggggg taaaggaagt ggtatctttg acgaatcaac ccccgtgcag    300

actcgacagc acctgaaccc acctggaggg aagaccagcg acatttttgg gtctccggtc    360

actgccactt cacgcttggc acacccaaac aaacccaagg atcatgtttt cttatgtgaa    420

ggagaagaac caaaatcgga tcttaaagct gcaaggagca tcccggctgg agcagagcca    480

ggtgagaaag gcagcgccag aaaagcaggc cccgccaagg agcaggagcc catgcccaca    540

gtcgacagcc atgagccccg gctggggccg cggcctcgct ctcacaacaa ggtcctgaac    600

ccaccgggag gcaaatccag catctccttc tactaagaga agccactgct ccacccggag    660

ccagaccaga aactcaagag atagggtagc catgttttca tttccttttg cccaaatgag    720

cggggtggga agagggttag tcttatgtga gcctggctgc tcagcgtctc ctggccgtca    780

tgacagctgc ttggagaccc gggccttcca natggctggg agatgcctct gtggggnatg    840

aaaang                                                               846


<210>  451
<211>  557
<212>  DNA
<213>  Homo sapiens

<400>  451
ccattaagaa ggaagaatta actatgagag gtcgcatcac catcaccatc acggatccta     60

tttaggtgac actatagaat cgtcgaccca cgcgtccgcc cacgcgtccg cccacgcgtc    120

cgcccacgcg tccggcgggg cgctcggctt cccgtgttcc tctccccgcc ccagccccgt    180

gggcgcgaga ggaggcgggg ggctccttgt gcaccagaga cgcagctgcc ttgttcgccc    240

ggtggggtgt ggatcctccg agcggtgctg ggaagggggt tctctctgcc cgcgcgccca    300

ggactctacc cagggcggag gtcccgagtg ggccgccccc cgcagcgccc tgggttcgcg    360

ggcccagagg ctggaggcag cggggagcta gggtccttca ccctcccctc gccgcgtgcc    420

tccgcaggag tcgggctccc cgttccccgc gatggccgcg ggccgcagtc gtacggagcc    480

gccgcgcgga ccccggggcg cccctcccta gcggggcgca gctccttctt gttccccgcc    540

ctgccagcgg gatgggg                                                   557


<210>  452
<211>  0
<212>  DNA
<213>  Homo sapiens

<400>  452
<210>  453
<211>  1083
<212>  DNA
<213>  Homo sapiens

<400>  453
atgtgcaagg ccggcttcgc gggcgacgat gccccccggg ccgtcttccc ctccatcgtg     60

gggcgcccca ggcaccaggg cgtgatggtg ggcatgggtc agaaggattc ctatgtgggc    120

gacgaggccc agagcaagag aggcatcctc accctgaagt accccatcga gcacggcatc    180

gtcaccaact gggacgacat ggagaaaatc tggcaccaca ccttctacaa tgagctgcgt    240

gtggctcccg aggagcaccc cgtgctgctg accgaggccc ccctgaaccc caaggccaac    300

ctcgagaaga tgacccagat catgtttgag accttcaaca ccccagccat gtacgttgct    360

atccaggctg tgctatccct gtacgcctct ggccgtacca ctggcatcgt gatggactcc    420

ggtgacgggg tcacccacac tgtgcccatc tacgaggggt atgccctccc ccatgccatc    480

ctgcgtctgg acctggctgg ccgggacctg actgactacc tcatgaagat cctcaccgag    540

cgcggctaca gcttcaccac cacggccgag cgggaaatcg tgcgtgacat taaggagaag    600

ctgtgctacg tcgccctgga cttcgagcaa gagatggcca cggctgcttc cagctcctcc    660

ctggagaaga gctacgagct gcctgacggc caggtcatca ccattggcaa tgagcggttc    720

cgctgccctg aggcactctt ccagccttcc ttcctgggca tggagtcctg tggcatccac    780

gaaactacct tcaactccat catgaagtgt gacgtggaca tccgcaaaga cctgtacgcc    840

aacacagtgc tgtctggcgg caccaccatg taccctggca ttgccgacag gatgcagaag    900

gagatcactg ccctggcacc cagcacaatg aagatcaaga tcattgctcc tcctgagcgc    960

aagtactccg tgtggatcgg cggctccatc ctggcctcgc tgtccacctt ccagcagatg   1020

tggatcagca agcaggagta tgacgagtcc ggcccctcca tcgtccaccg caaatgcttc   1080

tag                                                                 1083


<210>  454
<211>  1662
<212>  DNA
<213>  Homo sapiens

<400>  454
atgctgtccg tgcgcgttgc tgcggccgtg gtccgcgccc ttcctcggcg ggccggactg     60

gtctccagaa atgctttggg ttcatctttc attgctgcaa ggaacttcca tgcctctaac    120

actcatcttc aaaagactgg gactgctgag atgtcctcta ttcttgaaga gcgtattctt    180

ggagctgata cctctgttga tcttgaagaa actgggcgtg tcttaagtat tggtgatggt    240

attgcccgcg tacatgggct gaggaatgtt caagcagaag aaatggtaga gttttcttca    300

ggcttaaagg gtatgtcctt gaacttggaa cctgacaatg ttggtgttgt cgtgtttgga    360

aatgataaac taattaagga aggagatata gtgaagagga caggagccat tgtggacgtt    420

ccagttggtg aggagctgtt gggtcgtgta gttgatgccc ttggtaatgc tattgatgga    480

aagggtccaa ttggttccaa gacgcgtagg cgagttggtc tgaaagcccc cggtatcatt    540

cctcgaattt cagtgcggga accaatgcag actggcatta aggctgtgga tagcttggtg    600

ccaattggtc gtggtcagcg tgaactgatt attggtgacc gacagactgg gaaaacctca    660

attgctattg acacaatcat taaccagaaa cgtttcaatg atggatctga tgaaaagaag    720

aagctgtact gtatttatgt tgctattggt caaaagagat ccactgttgc ccagttggtg    780

aagagactta cagatgcaga tgccatgaag tacaccattg tggtgtcggc tacggcctcg    840

gatgctgccc cacttcagta cctggctcct tactctggct gttccatggg agagtatttt    900

agagacaatg gcaaacatgc tttgatcatc tatgacgact tatccaaaca ggctgttgct    960

taccgtcaga tgtctctgtt gctccgccga ccccctggtc gtgaggccta tcctggtgat   1020

gtgttctacc tacactcccg gttgctggag agagcagcca aaatgaacga tgcttttggt   1080

ggtggctcct tgactgcttt gccagtcata gaaacacagg ctggtgatgt gtctgcttac   1140

attccaacaa atgtcatttc catcactgac ggacagatct tcttggaaac agaattgttc   1200

tacaaaggta tccgccctgc aattaacgtt ggtctgtctg tatctcgtgt cggatccgct   1260

gcccaaacca gggctatgaa gcaggtagca ggtaccatga agctggaatt ggctcagtat   1320

cgtgaggttg ctgcttttgc ccagttcggt tctgacctcg atgctgccac tcaacaactt   1380

ttgagtcgtg gcgtgcgtct aactgagttg ctgaagcaag gacagtattc tcccatggct   1440

attgaagaac aagtggctgt tatctatgcg ggtgtaaggg gatatcttga taaactggag   1500

cccagcaaga ttacaaagtt tgagaatgct ttcttgtctc atgtcgtcag ccagcaccaa   1560

gccttgttgg gcactatcag ggctgatgga aagatctcag aacaatcaga tgcaaagctg   1620

aaagagattg taacaaattt cttggctgga tttgaagctt aa                      1662


<210>  455
<211>  1590
<212>  DNA
<213>  Homo sapiens

<400>  455
atgttggggt ttgtgggtcg ggtggccgct gctccggcct ccggggcctt gcggagactc     60

accccttcag cgtcgctgcc cccagctcag ctcttactgc gggccgctcc gacggcggtc    120

catcctgtca gggactatgc ggcgcaaaca tctccttcgc caaaagcagg cgccgccacc    180

gggcgcatcg tggcggtcat tggcgcagtg gtggacgtcc agtttgatga gggactacca    240

ccaattctaa atgccctgga agtgcaaggc agggagacca gactggtttt ggaggtggcc    300

cagcatttgg gtgagagcac agtaaggact attgctatgg atggtacaga aggcttggtt    360

agaggccaga aagtactgga ttctggtgca ccaatcaaaa ttcctgttgg tcctgagact    420

ttgggcagaa tcatgaatgt cattggagaa cctattgatg aaagaggtcc catcaaaacc    480

aaacaatttg ctcccattca tgctgaggct ccagagttca tggaaatgag tgttgagcag    540

gaaattctgg tgactggtat caaggttgtc gatctgctag ctccctatgc caagggtggc    600

aaaattgggc tttttggtgg tgctggagtt ggcaagactg tactgatcat ggagttaatc    660

aacaatgtcg ccaaagccca tggtggttac tctgtgtttg ctggtgttgg tgagaggacc    720

cgtgaaggca atgatttata ccatgaaatg attgaatctg gtgttatcaa cttaaaagat    780

gccacctcta aggtagcgct ggtatatggt caaatgaatg aaccacctgg tgctcgtgcc    840

cgggtagctc tgactgggct gactgtggct gaatacttca gagaccaaga aggtcaagat    900

gtactgctat ttattgataa catctttcgc ttcacccagg ctggttcaga ggtgtctgca    960

ttattgggcc gaatcccttc tgctgtgggc tatcagccta ccctggccac tgacatgggt   1020

actatgcagg aaagaattac cactaccaag aagggatcta tcacctctgt acaggctatc   1080

tatgtgcctg ctgatgactt gactgaccct gcccctgcta ctacgtttgc ccatttggat   1140

gctaccactg tactgtcgcg tgccattgct gagctgggca tctatccagc tgtggatcct   1200

ctagactcca cctctcgtat catggatccc aacattgttg gcagtgagca ttacgatgtt   1260

gcccgtgggg tgcaaaagat cctgcaggac tacaaatccc tccaggatat cattgccatc   1320

ctgggtatgg atgaactttc tgaggaagac aagttgaccg tgtcccgtgc acggaaaata   1380

cagcgtttct tgtctcagcc attccaggtt gctgaggtct tcacaggtca tatggggaag   1440

ctggtacccc tgaaggagac catcaaagga ttccagcaga ttttggcagg tgaatatgac   1500

catctcccag aacaggcctt ctatatggtg ggacccattg aagaagctgt ggcaaaagct   1560

gataagctgg ctgaagagca ttcatcgtga                                    1590


<210>  456
<211>  1125
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (232)..(232)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (475)..(475)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (553)..(553)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (596)..(596)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (608)..(608)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (635)..(635)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (649)..(649)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (657)..(657)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (715)..(715)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (730)..(730)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (735)..(735)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (747)..(747)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (752)..(752)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (765)..(766)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (779)..(779)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (787)..(788)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (827)..(828)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (843)..(843)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (845)..(845)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (861)..(861)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (882)..(882)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (886)..(886)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (889)..(889)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (899)..(900)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (908)..(909)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (911)..(913)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (929)..(929)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (933)..(933)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (942)..(942)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (948)..(948)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(957)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (970)..(970)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (976)..(976)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (985)..(986)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (991)..(991)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1008)..(1008)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1016)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1024)..(1024)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1032)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1041)..(1042)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1049)..(1050)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1052)..(1052)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1054)..(1054)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1065)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1067)..(1067)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1075)..(1075)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1078)..(1078)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1090)..(1090)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1094)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1105)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1116)..(1117)
<223>  n is a, c, g, or t

<400>  456
gaatagagag attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cgggtttggt tgtgagatcg agaataacag    120

aagcagcgga gcattctgga aatattacta tgatggaaag gactacattg aattcaacaa    180

agaaatccca gcctgggtcc ccttcgaccc agcagcccag ataaccaagc anaagtggga    240

ggcagaacca gtctacgtgc agcgggccaa ggcttacctg gaggaggagt gccctgcgac    300

tctgcggaaa tacctgaaat acagcaaaaa tatcctggac cggcaagatc ctccctctgt    360

ggtggtcacc agccaccagg ccccaggaga aaagaagaaa ctgaagtgcc tggcctacga    420

cttctaccca gggaaaattg atgtgcactg gactcgggcc ggcgaggtgc aggancctga    480

gttacgggga gatgttcttc acaatggaaa tggcacttac cagtcctggg tggtggtggc    540

agtgcccccg cangacacag ccccctactc ctgccacgtg cagcacagca gcctgnccca    600

gcccctcntg gtgccctggg aggccagcta ggaancaagg gttggaggna atgtggnatc    660

tcaaacccag taagctgccc ttcctgcctg atgtgggagc tgaaccacag aaatncacat    720

gtcaatggan ccacnaggcc ctgaagnagc antgtggggg ggacnnaaca ggaggttgna    780

tttggannac cgaaagactg ggatgcctgt cttgaagtat aacttgnnac ccaaaaaaaa    840

tcntntcacc cttgagcccc ncccccaccc cccttggtct antctngtna gaagctaann    900

aaaataannc nnnccctcct ttccctaanc aanaaaaatg antaatanac taaaanntta    960

ttttctactn agggcnggcc ccccnnccat naaggagtcc ncaatnanat cttaantcac   1020

cttnatcttt gncaccctgt nnaaaaaann cncnaaattg actcncnaac ctccnttncg   1080

aattgttttn aaanactctc gttnngcccc ggcgtnnatt ttttt                   1125


<210>  457
<211>  1400
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1022)..(1022)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1119)..(1119)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1128)..(1128)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1179)..(1179)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1198)..(1198)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1212)..(1212)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1217)..(1217)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1220)..(1221)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1243)..(1243)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1266)..(1266)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1278)..(1280)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1355)..(1355)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1368)..(1368)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1371)..(1371)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1394)..(1394)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1396)..(1396)
<223>  n is a, c, g, or t

<400>  457
nnnggatata ctgacttacc tataaatagg cgtatcacga ggccctttcg tcttcacctc     60

gagaaatcat aaaaaattta tttgctttgt gagcggataa caattataat agattcaatt    120

gtgagcggat aacaatttca cacagaattc attaaagagg agaaattaac tatgagagga    180

tcgcatcacc atcaccatca cggtcgaccc acgcgtccgc ggccgcggcc gcctacaccc    240

ctatacccca tgatgtgccc catggaacac cccctttctg ctgacatcgc catggccacc    300

cgtgcagatg aggacggaga cacgcctctc catattgctg tggtgcaggg taacctgcca    360

gctgtgcacc ggctggtcaa cctcttccag caggggggcc gggagctcga catctacaac    420

aacctacggc agacaccgct ccacctggct gtgatcacca cattaccgtc tgtggtccgg    480

ctcctggtga cagctggtgc cagccccatg gcgctggacc gccatggcca gacggccgct    540

cacctggcgt gcgagcaccg cagcccgacc tgcctgcgag ccctgctgga cagcgcagct    600

ccgggcacgt tggacctgga ggcccgcaat tatgacgggc tcaccgccct gcacgtggca    660

gtgaacaccg agtgccaaga aaccgtgcag ctcttgctag agcgcggtgc cgacatcgac    720

gcagtggaca ttaagagcgg ccgctccccg ctcatccacg ccgtggaaaa caacagcctt    780

aacatggggc aactgctgct gcagcacggc gccaacctga acgcgcaaat ggacttccgg    840

cagctccgcc ctgcactcaa gcgtccggcc gccgggctcc ctcccgctgg gggcgcacgc    900

gggtccccca acgggcctaa aaaaaaaccc tcaaaaaatt ggcccaacaa acacccgccc    960

taatgggggg ggcccaaccc ccaagggcaa ctcaacaatc tgaaagggga aaagccccca   1020

cnagccgggt ctacaccacg gacagacata acgccaagaa accctcaaaa agccaactcc   1080

agcgaccccc ttagaaaaaa ccacacgaca acagccaana accccccncg cgaccatata   1140

aacccaacgc cagcaatacc cgccccccac caattatang tacacaaaca cccccaancc   1200

acaaccacac cnaaacncan naaacccacc acaaacacaa canaccccca aaacaacaca   1260

ccaccncaca ctcaaacnnn tcaaacgccc acacatacac accaaaaacc acaaacaaca   1320

cggcttcacg acccgaacaa caaccaccca ccacncataa cccaaatnac ncacacacaa   1380

taaacaacac ccanancaca                                               1400


<210>  458
<211>  1437
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (14)..(14)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (16)..(16)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1376)..(1376)
<223>  n is a, c, g, or t

<400>  458
nnccgcaccc cccncnctaa gaattactag agaggatcgc atcaccatca ccatcacggt     60

cgacccacgc gtccgcttcg agacaccaag tccacagatc agaagatgac gttgttacac    120

ttcttggctg agttgtgtga gaatgactat cccgatgtcc tcaagtttcc agacgagctt    180

gcccatgtgg agaaagccag ccgagtttct gctgaaaact tgcaaaagaa cctagatcag    240

atgaagaaac aaatttctga tgtggaacgt gatgttcaga atttcccagc tgccacagat    300

gaaaaagaca agtttgttga aaaaatgacc agctttgtga aggatgcaca ggaacagtat    360

aacaagctgc ggatgatgca ttctaacatg gagaccctct ataaggagct gggcgagtac    420

ttcctctttg accccaagaa gttgtctgtt gaagaatttt tcatggatct tcacaatttt    480

cggaatatgt ttttgcaagc agtcaaggag aaccagaagc ggcgggagac agaagaaaag    540

atgaggcgag caaaactagc caaggagaag gcagagaagg agcggctaga gaagcagcag    600

aagagagagc aactcataga catgaatgca gagggcgatg agacaggtgt gatggacagt    660

cttctagaag ccctgcagtc aggggcagca ttccgacgga agagagggcc ccgtcaagcc    720

aacaggaagg ccgggtgtgc agtcacatct ctgctagctt cggagctgac caaggatgat    780

gccatggctg ctgttcctgc ccaggtgtcc aagaacagtg agacattccc cacaatcctt    840

gaggaagcca aaggagtggt tggccgtgca gctaatgtgg gtcctgtgac cgcggcagct    900

cctcagcgga gccgcagact gtcctgccct gcagcatgtg cctaaaggct caaggggaat    960

cccctcctgg ggtggcactt cccaccaccc gaccctgtct ttctctctgg gccgctgctc   1020

tctcaacatc acatacagct tccactggct ggagggcaaa aaggaaaggc cagtgccacg   1080

gaaagcctga acccgaactt accaaccccg gtttgttcta ttaccaacca agcccccagg   1140

ttcctaccct aaccctctcc ccatcctgaa ccccaaacaa cctcactcct accagcgccc   1200

cccgctcctt ctcatcctca gctttacatg ggcttctcca ccccccccaa cctacctccc   1260

taagcaccct ccacatctct caaacccact aaccaacttt actccccatc caccacttct   1320

tacaccccct ccacctggac tttccactct ccattctaac tcgtcaccac cacatnctca   1380

tcaccttctc gacccccacg ccacgccacc cacaccacac ccaattacac acttcca      1437


<210>  459
<211>  1182
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (913)..(913)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (915)..(928)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (930)..(935)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (960)..(960)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (973)..(975)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (999)..(999)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1026)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1044)..(1044)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1046)..(1046)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1051)..(1051)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1055)..(1055)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1058)..(1058)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1078)..(1078)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1083)..(1083)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1113)..(1113)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1128)..(1128)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1132)..(1132)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1135)..(1135)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1137)..(1137)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1159)..(1161)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1166)..(1166)
<223>  n is a, c, g, or t

<400>  459
nnattagaga aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgcctgcat taaccagccc cagttccggg    120

ctgtcttggg ggaagtgaaa ctgtgtgaga agatggccca gtttgatgct aaaaagtttg    180

cagagaccca acctaaaaag gacacaccac ggaaagagaa gggttcacgg gaagagaagc    240

agaagcccca ggctgagcgg aaggaggaga aaaaggcggc tgcccctgct cctgaggagg    300

agatggatga atgtgagcag gcgctggctg ctgagcccaa ggccaaggac cccttcgctc    360

acctgcccaa gagtaccttt gtgttggatg aatttaagcg caagtactcc aatgaggaca    420

cactctctgt ggcactgcca tatttctggg agcactttga taaggacggc tggtccctgt    480

ggtactcaga gtatcgcttc cctgaagaac tcactcagac cttcatgagc tgcaatctca    540

tcactggaat gttccagcga ctggacaagc tgaggaagaa tgccttcgcc agtgtcatcc    600

tttttggaac caacaatagc agctccattt ctggagtctg ggtcttccga ggccaggagc    660

ttgcctttcc gctgagtcca gattggcagg tggactacga gtcatacaca tggcggaaac    720

tggatcctgg cagcgaggag acccagacgc tggttcgaga gtacttttcc tgggaggggg    780

ccttccagca tgtgggcaaa gccttcaatc agggcaagat cttcaagtga acatctcttg    840

ccatcaccta gctgcctgca cctgcccttc agggagatgg gggtcattaa aggaaactga    900

acattgaaaa aanannnnnn nnnnnnnnan nnnnnaaaag ggggggccgc tccctatagn    960

gagtcgtatt aannnttaat tacctgaact tggaactcng gttganaaat ccagtaatga   1020

cccccnaaac tccctctgga tttntncaaa ncccncgntt gcccccgggn gttttttntt   1080

ggngaaaatc caagctagct gggcgaaaat ttncgggaac taaggaangc tnaantnggg   1140

aaaaaaaatc cctgggaann nccccngttt aatttcccat gg                      1182


<210>  460
<211>  1171
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (810)..(810)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (948)..(948)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (969)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1009)..(1009)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1022)..(1022)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1029)..(1029)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1045)..(1045)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1054)..(1054)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1056)..(1056)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1067)..(1067)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1078)..(1078)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1092)..(1092)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1109)..(1109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1113)..(1113)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1121)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1124)..(1124)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1128)..(1128)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1138)..(1138)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1145)..(1145)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1153)..(1153)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1165)..(1165)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1171)..(1171)
<223>  n is a, c, g, or t

<400>  460
attagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gggatcatgt ctgcgagcca ggattcccga    120

tccagagaca atggccccga tgggatggag cccgaaggcg tcatcgagag taactggaat    180

gagattgttg acagctttga tgacatgaac ctctcggagt cccttctccg tggcatctac    240

gcctatggtt ttgagaagcc ctctgccatc cagcagcgag ccattctacc ttgtatcaag    300

ggttatgatg tgattgctca agcccaatct gggactggga aaacggccac atttgccata    360

tcgattctgc agcagattga attagatcta aaagccaccc aggccttggt cctagcaccc    420

actcgagaat tggctcagca gatacagaag gtggtcatgg cactaggaga ctacatgggc    480

gcctcctgtc acgcctgtat cgggggcacc aacgtgcgtg ctgaggtgca gaaactgcag    540

atggaagctc cccacatcat cgtgggtacc cctggccgtg tgtttgatat gcttaaccgg    600

agatacctgt cccccaaata catcaagatg tttgtactgg atgaagctga cgaaatgtta    660

agccgtggat tcaaggacca gatctatgac atattccaaa agctcaacag caacacccag    720

gtagttttgc tgtcagccac aatgccttct gatgtgcttg aggtgaccaa gaagttcatg    780

agggacccca ttcggattct tgtcaagaan gaagagttga ccctggaggg tatccgccag    840

ttctacatca acgtggaacg agaggagtgg aagctggaca cactatgtga cttgtatgaa    900

accctgacca tcacccaggc agtcatcttc atcaacaccc ggaggaangt ggactggctc    960

accganaana tgcatgctcg aaatttcnct gtatccncca tgcatggana tatggaccaa   1020

angaacgana cgtgattatg agggntttcg ttcngnctct accaaanttt tgattacnct   1080

gacctgctgg cnaaagcatt gatgtgcanc agntttttta ntcntcanct aagacctncc   1140

cccanaggga aantatttcc caaantcgtc n                                  1171


<210>  461
<211>  1280
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (823)..(823)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (861)..(861)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (893)..(893)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (939)..(939)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (945)..(945)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (947)..(947)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (949)..(949)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (973)..(973)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (979)..(979)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (983)..(984)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (991)..(991)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1002)..(1002)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1027)..(1028)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1031)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1051)..(1051)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1057)..(1057)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1066)..(1066)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1072)..(1072)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1076)..(1076)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1087)..(1087)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1090)..(1090)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1094)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1109)..(1109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1123)..(1123)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1125)..(1126)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1128)..(1128)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1133)..(1133)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1138)..(1138)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1140)..(1141)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1147)..(1147)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1156)..(1156)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1158)..(1158)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1161)..(1161)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1184)..(1184)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1188)..(1188)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1194)..(1194)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1202)..(1202)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1204)..(1204)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1214)..(1214)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1225)..(1226)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1249)..(1249)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1256)..(1256)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1279)..(1280)
<223>  n is a, c, g, or t

<400>  461
tagagagatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc ccacgcgtcc gaaccgccgc caggtcgctg    120

ttggtccacg ccgcccgtcg cgccgcccgc ccgctcagcg tccgccgccg ccatgggagt    180

gcaggtggaa accatctccc caggagacgg gcgcaccttc cccaagcgcg gccagacctg    240

cgtggtgcac tacaccggga tgcttgaaga tggaaagaaa tttgattcct cccgggacag    300

aaacaagccc tttaagttta tgctaggcaa gcaggaggtg atccgaggct gggaagaagg    360

ggttgcccag atgagtgtgg gtcagagagc caaactgact atatctccag attatgccta    420

tggtgccact gggcacccag gcatcatccc accacatgcc actctcgtct tcgatgtgga    480

gcttctaaaa ctggaatgac aggaatggcc tcctccctta gctccctgtt cttggatctg    540

ccgtggaggg atctggtgcc tccagacatg tgcacatgag tccatatgga gcttttcctg    600

atgttccact ccactttgta tagacatctg ccctgactga atgtgttctg tcactcagct    660

ttgcttccga cacctctgtt tcctcttccc ctttctcctc gtatgtgtgt ttacctaaac    720

tatatgccat aaacctcaag ttactcattt tattttgttt tcattttggg gtgaagattc    780

agtttcagtc ttttggatat aggtttccaa ttaagtacat ggntcaaagt attaacagca    840

caagtggtaa gttaacatta naataggaat tggtgtttgg gggggggggt ttngcaaaga    900

aaaattttat tttaattttt ttggaaggaa atttttaanc taatnanana ttaaaacatt    960

tcttgnctgc tgngctgcna aannccataa ncaaaatttt anggcccttg tttgaagaac   1020

tgaaatnnct ntcccaagtt tgaaaaaaat ntttttnggt ttaaantaaa ancccntacc   1080

ttaaaantgn aggnggggaa nggggnaana accttttgcc ttnannantt ccnacccnan   1140

nctcccnttt aaaccntncg ncttttaaaa aaaaattatg tttncttnca atgngggaaa   1200

cntnaaggat tttntccttg ggccnncagg gacctttgaa acctttttng tgggcntttt   1260

ttttttcccc ggggttttnn                                               1280


<210>  462
<211>  552
<212>  DNA
<213>  Homo sapiens

<400>  462
atgacgaccg cgtccacctc gcaggtgcgc cagaactacc accaggactc agaggccgcc     60

atcaaccgcc agatcaacct ggagctctac gcctcctacg tttacctgtc catgtcttac    120

tactttgacc gcgatgatgt ggctttgaag aactttgcca aatactttct tcaccaatct    180

catgaggaga gggaacatgc tgagaaactg atgaagctgc agaaccaacg aggtggccga    240

atcttccttc aggatatcaa ggaaccagac tgtgatgact gggagagcgg gcagaatgca    300

atggagtgtg cattacattt ggaaaaaaat gtgaatcagt cactactgga actgcacaaa    360

ctggccactg acaaaaatga cccccatttg tgtgacttca ttgagacaca ttacctgaat    420

gagcaggtga aagccatcaa agaattgggt gaccacgtga ccaacttgcg caagatggga    480

gcgcccgaat ctggcttggc ggaatatctc tttgacaagc acaccctggg agacagtgat    540

aatgaaagct aa                                                        552


<210>  463
<211>  1008
<212>  DNA
<213>  Homo sapiens

<400>  463
atggggaagg tgaaggtcgg agtcaacgga tttggtcgta ttgggcgcct ggtcaccagg     60

gctgctttta actctggtaa agtggatatt gttgccatca atgacccctt cattgacctc    120

aactacatgg tttacatgtt ccaatatgat tccacccatg gcaaattcca tggcaccgtc    180

aaggctgaga acgggaagct tgtcatcaat ggaaatccca tcaccatctt ccaggagcga    240

gatccctcca aaatcaagtg gggcgatgct ggcgctgagt acgtcgtgga gtccactggc    300

gtcttcacca ccatggagaa ggctggggct catttgcagg ggggagccaa aagggtcatc    360

atctctgccc cctctgctga cgcccccatg ttcgtcatgg gtgtgaacca tgagaagtat    420

gacaacagcc tcaagatcat cagcaatgcc tcctgcacca ccaactgctt agcacccctg    480

gccaaggtca tccatgacaa ctttggtatc gtggaaggac tcatgaccac agtccatgcc    540

atcactgcca cccagaagac tgtggatggc ccctccggga aactgtggcg tgatggccgc    600

ggggctctcc agaacatcat ccctgcctct actggcgctg ccaaggctgt gggcaaggtc    660

atccctgagc tgaacgggaa gctcactggc atggccttcc gtgtccccac tgccaacgtg    720

tcagtggtgg acctgacctg ccgtctagaa aaacctgcca aatatgatga catcaagaag    780

gtggtgaagc aggcgtcgga gggccccctc aagggcatcc tgggctacac tgagcaccag    840

gtggtctcct ctgacttcaa cagcgacacc cactcctcca ccttcgacgc tggggctggc    900

attgccctca acgaccactt tgtcaagctc atttcctggt atgacaacga atttggctac    960

agcaacaggg tggtggacct catggcccac atggcctcca aggagtaa                1008


<210>  464
<211>  1050
<212>  DNA
<213>  Homo sapiens

<400>  464
atggctagca agaaagtctg cattgtaggc tccgggaact ggggctcagc catcgccaag     60

atcgtgggtg gcaatgcagc ccagctggca cagtttgacc cacgggtgac catgtgggta    120

tttgaggaag acattggagg caaaaagctg actgagatca tcaacacgca gcatgagaat    180

gtcaaatacc tgccagggca caagttgccc ccaaatgtgg tggctgtccc agatgtggtc    240

caggctgcag aggatgctga catcctgatc tttgtggtgc cccatcagtt catcggcaag    300

atctgtgacc agctcaaggg ccatctgaag gcaaacgcca ctggcatatc tcttattaag    360

ggggtagacg agggccccaa tgggctgaag ctcatctcgg aagtgattgg ggagcgcctc    420

ggcatcccca tgagtgtgct gatgggggcc aacattgcca gcgaggtggc tgatgagaag    480

ttctgtgaga caaccattgg ctgcaaggac ccggcccagg gacaactcct gaaagagctg    540

atgcagacac caaacttccg tatcacagtg gtgcaagagg tggacacagt agagatctgt    600

ggagccttaa agaatgtagt ggccgtgggg gctggcttct gtgatggcct gggctttggc    660

gacaacacca aggcggcagt gatccggctg ggactcatgg agatgatagc cttcgccaag    720

ctcttctgca gtggccctgt gtcctctgcc accttcttgg agagctgtgg tgttgctgac    780

ctgatcacta cctgctatgg agggcggaac cggaaagtgg ctgaggcctt tgcgcgtaca    840

ggaaagtcca ttgagcagct ggagaaagag ttgctgaatg ggcagaaact gcaggggccc    900

gagacagccc gggagctata cagcatcctc cagcacaagg gcctggtaga caagtttccc    960

ttgttcatgg ctgtgtacaa ggtgtgctac gagggccagc cagtgggtga attcatccac   1020

tgcctgcaga atcatccaga acatatgtga                                    1050


<210>  465
<211>  1227
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (968)..(968)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (970)..(970)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (975)..(975)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1007)..(1007)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1010)..(1010)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1017)..(1017)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1031)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1065)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1089)..(1089)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1094)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1100)..(1100)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1111)..(1111)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1113)..(1113)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1115)..(1115)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1132)..(1132)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1134)..(1134)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1153)..(1153)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1168)..(1168)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1170)..(1170)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1182)..(1183)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1191)..(1191)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1201)..(1201)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1204)..(1204)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1209)..(1209)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1214)..(1215)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1220)..(1220)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1225)..(1225)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1227)..(1227)
<223>  n is a, c, g, or t

<400>  465
atagagaaat tactatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactataga atcgtcgacc cacgcgtccg gccagaaact ccctccattt tcttatgctt    120

atacggaact ggaagctatt atgtatgccc ttggagtggg agcgtcaatc aaggatccaa    180

aagatttgaa atttatttat gaaggaagtt ctgatttctc ctgtttgccc accttcggag    240

ttatcatagg tcagaaatct atgatgggtg gaggattagc agaaattcct ggactttcaa    300

tcaactttgc aaaggttctt catggagagc agtacttaga gttatataaa ccacttccca    360

gagcaggaaa attaaaatgt gaagcagttg ttgctgatgt cctagataaa ggatccggtg    420

tagtgattat tatggatgtc tattcttatt ctgagaagga acttatatgc cacaatcagt    480

tctctctctt tcttgttggc tctggaggct ttggtggaaa acggacatca gacaaagtca    540

aggtagctgt agccatacct aatagacctc ctgatgctgt acttacagat accacctctc    600

ttaatcaggc tgctttgtac cgcctcagtg gagactggaa tcccttacac attgatccta    660

actttgctag tctagcaggt tttgacaagc ccatattaca tggattatgt acatttggat    720

tttctgccag gcgtgtgtta cagcagtttg cagataatga tgtgtcaaga ttcaaggcag    780

ttaaggctcg ttttgcaaaa ccagtatatc caggacaaac tctacaaact gagatgtgga    840

aggaaggaaa cagaattcat tttcaaacca aggtccaaga aactggagac attgtcattt    900

caaatgcata tgtggatctt gcaccaacat ctggtacttc agctaaaaca ccctctgagg    960

gcgggnancn tccanantac ctttgtattt gaggaaatag gaccccnccn aaagganatt   1020

gggcctgagg nggtgaaaaa agtaaatgct gtatttgagt ggcanaaacc naaggcggaa   1080

aaattgggnc taanggacan tgacctgaaa ngngntctgg aaaatgtacc angncccgca   1140

aagggctgct gancaacaat ccaacttncn aaaaaaaatt cnnggggggg nccgggcaac   1200

ntgnccccna aggnnttttn tggcngn                                       1227


<210>  466
<211>  1926
<212>  DNA
<213>  Homo sapiens

<400>  466
atggctactg ccaagggaat cgccataggc atcgacctgg gcaccaccta ctcctgtgtg     60

ggggtgttcc agcacggcaa ggtggagatc atcgccaacg accagggcaa ccgcaccacc    120

cccagctacg tggccttcac agacaccgag cggctcattg gggatgcggc caagaaccag    180

gtagcaatga atccccagaa cactgttttt gatgctaaac gtctgatcgg caggaaattt    240

aatgatcctg ttgtacaagc agatatgaaa ctttggcctt ttcaagtgat taatgaagga    300

ggcaagccca aagtccttgt gtcctacaaa ggggagaata aagctttcta ccctgaggaa    360

atctcttcga tggtattgac taagttgaag gagactgctg aggccttttt gggccaccct    420

gtcaccaatg cagtgattac cgtgccagcc tatttcaatg actctcaacg tcaggctact    480

aaggatgcag gtgtgattgc tggacttaat gtgctaagaa tcatcaatga gcccacggct    540

gctgccattg cctatggttt agataaagga ggtcaaggag aacgacatgt cctgattttt    600

gatctgggtg gaggcacatt tgatgtgtca attctgacca tagatgatgg gatttttgag    660

gtaaaggcca ctgctgggga cactcacctg ggtggggagg actttgacaa caggcttgtg    720

agccacttcg tggaggagtt caagaggaaa cacaaaaagg acatcagcca gaacaagcga    780

gccgtgaggc ggctgcgcac cgcctgcgag agggccaaga ggaccctgtc gtccagcacc    840

caggccaacc tagaaattga ttcactttat gaaggcattg acttctatac atccatcacc    900

agagctcgat ttgaagagtt gtgtgcagac ctgtttaggg gtaccctgga gcctgtagaa    960

aaagcgcttc gggatgccaa gatggataag gctaaaatcc atgacattgt tttagtaggg   1020

ggctccaccc gcatccccaa ggtgcagcgg ctgcttcagg actacttcaa tggacgtgat   1080

ctcaacaaga gcatcaaccc tgatgaggcc gtagcatatg gggctgcggt acaagcagcc   1140

atcctgatgg gggacaagtc tgagaaggta caggacctgc tgctgctgga cgtggctccc   1200

ctgtccctgg ggctggagac ggctgggggc gtgatgactg ccttgatgaa gcgcaactcc   1260

accatcccca ccaagcagac acagattttc accacctact ctgacaacca acccggggtg   1320

ctgatccagg tgtatgaggg cgagagggcc atgacaaagg acaacaacct gctggggcgg   1380

tttgacctga ctggaatccc tccagcaccc aggggagttc ctcagatcga ggtgacgttt   1440

gacattgatg ccaatggtat tctcaatgtc acagccatgg acaagagcac cggcaaggtg   1500

aacaagatca ccatcgccaa tgacaagggc cgcctgagca aggaggagat tgagcgcatg   1560

gttctggatg ctgagaaata taaagctgaa gatgaggtcc agagggagaa aattgctgca   1620

aagaatgcct tagaatccta tgcttttaac atgaagagtg ttgtgagtga tgaaggtttg   1680

aagggcaaga ttagtgagtc tgataaaaat aaaatattgg ataaatgcaa cgagctcctt   1740

tcgtggctgg aggtcaatca actggcagag aaagatgagt ttgatcataa gagaaaggaa   1800

ttggagcaga tgtgtaaccc tatcatcaca aaactctacc aaggaggatg cactgggcct   1860

gcctgcggaa cagggtatgt gcctggaagg cctgccacag gccccacaat tgaagaagta   1920

gattaa                                                              1926


<210>  467
<211>  1941
<212>  DNA
<213>  Homo sapiens

<400>  467
atgtccaagg gacctgcagt tggtattgat cttggcacca cctactcttg tgtgggtgtt     60

ttccagcacg gaaaagtcga gataattgcc aatgatcagg gaaaccgaac cactccaagc    120

tatgtcgcct ttacggacac tgaacggttg atcggtgatg ccgcaaagaa tcaagttgca    180

atgaacccca ccaacacagt ttttgatgcc aaacgtctga ttggacgcag atttgatgat    240

gctgttgtcc agtctgatat gaaacattgg ccctttatgg tggtgaatga tgctggcagg    300

cccaaggtcc aagtagaata caagggagag accaaaagct tctatccaga ggaggtgtct    360

tctatggttc tgacaaagat gaaggaaatt gcagaagcct accttgggaa gactgttacc    420

aatgctgtgg tcacagtgcc agcttacttt aatgactctc agcgtcaggc taccaaagat    480

gctggaacta ttgctggtct caatgtactt agaattatta atgagccaac tgctgctgct    540

attgcttacg gcttagacaa aaaggttgga gcagaaagaa acgtgctcat ctttgacctg    600

ggaggtggca cttttgatgt gtcaatcctc actattgagg atggaatctt tgaggtcaag    660

tctacagctg gagacaccca cttgggtgga gaagattttg acaaccgaat ggtcaaccat    720

tttattgctg agtttaagcg caagcataag aaggacatca gtgagaacaa gagagctgta    780

agacgcctcc gtactgcttg tgaacgtgct aagcgtaccc tctcttccag cacccaggcc    840

agtattgaga tcgattctct ctatgaagga atcgacttct atacctccat tacccgtgcc    900

cgatttgaag aactgaatgc tgacctgttc cgtggcaccc tggacccagt agagaaagcc    960

cttcgagatg ccaaactaga caagtcacag attcatgata ttgtcctggt tggtggttct   1020

actcgtatcc ccaagattca gaagcttctc caagacttct tcaatggaaa agaactgaat   1080

aagagcatca accctgatga agctgttgct tatggtgcag ctgtccaggc agccatcttg   1140

tctggagaca agtctgagaa tgttcaagat ttgctgctct tggatgtcac tcctctttcc   1200

cttggtattg aaactgctgg tggagtcatg actgtcctca tcaagcgtaa taccaccatt   1260

cctaccaagc agacacagac cttcactacc tattctgaca accagcctgg tgtgcttatt   1320

caggtttatg aaggcgagcg tgccatgaca aaggataaca acctgcttgg caagtttgaa   1380

ctcacaggca tacctcctgc accccgaggt gttcctcaga ttgaagtcac ttttgacatt   1440

gatgccaatg gtatactcaa tgtctctgct gtggacaaga gtacgggaaa agagaacaag   1500

attactatca ctaatgacaa gggccgtttg agcaaggaag acattgaacg tatggtccag   1560

gaagctgaga agtacaaagc tgaagatgag aagcagaggg acaaggtgtc atccaagaat   1620

tcacttgagt cctatgcctt caacatgaaa gcaactgttg aagatgagaa acttcaaggc   1680

aagattaacg atgaggacaa acagaagatt ctggacaagt gtaatgaaat tatcaactgg   1740

cttgataaga atcagactgc cgagaaggaa gaatttgaac atcaacagaa agagctggag   1800

aaagtttgca accccatcat caccaagctg taccagagtg caggaggcat gccaggagga   1860

atgcctgggg gatttcctgg tggtggagct cctccctctg gtggtgcttc ctcagggccc   1920

accattgaag aggttgatta a                                             1941


<210>  468
<211>  979
<212>  DNA
<213>  Homo sapiens

<400>  468
taactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt gacactatag     60

aatcgtcgac ccacgcgtcc gccgacaaat gcaaatgcgt ggacttccag accctgaagc    120

tgcaggagct gcctgatgca gtcccccacg gggagatgcc cagacacatg cagctctact    180

gcgacaggta cctgtgtgac aaggtcgtcc ctgggaacag ggttaccatc atgggcatct    240

actccatcaa gaagtttggc ctgactacca gcaggggccg tgacagggtg ggcgtgggca    300

tccgaagctc ctacatccgt gtcctgggca tccaggtgga cacagatggc tctggccgca    360

gctttgctgg ggccgtgagc ccccaggagg aggaggagtt ccgtcgcctg gctgccctcc    420

caaatgtcta tgaggtcatc tccaagagca tcgccccctc catctttggg ggcacagaca    480

tgaagaaggc cattgcctgc ctgctctttg ggggctcccg aaagaggctc cctgatggac    540

ttactcgccg aggagacatc aacctgctga tgctagggga ccctgggaca gccaagtccc    600

agcttctgaa gtttgtggag aagtgttctc ccattggggt atacacgtct gggaaaggca    660

gcagcgcagc tggactgaca gcctcggtga tgagggaccc ttcgtcccgg aatttcatca    720

tggagggcgg agccatggtc ctggccgatg gtggggtcgt ctgtattgac gagtttgaca    780

agatgcgaga agatgaccgt gtggcaatcc acgaagccat ggagcagcag accatctcta    840

tcgccaaggc tgggatcacc accaccctga actcccgctg ctccgtcctg gctgctgcca    900

actcagtgtt cggccgctgg gatgagacga agggggagga caacattgac ttcatgccca    960

ccatcttgtc gcgcttcga                                                 979


<210>  469
<211>  1190
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (14)..(14)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (981)..(981)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1037)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1109)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1134)..(1134)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1137)..(1137)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1141)..(1141)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1155)..(1155)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1160)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1164)..(1166)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1171)..(1171)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1174)..(1178)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1184)..(1184)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1189)..(1189)
<223>  n is a, c, g, or t

<400>  469
nncccgttct tccnctaaga gatactagag aggatcgcat caccatcaca tcacggtcga     60

cccacgcgtc cgcaccggga cattaaggga gccaacatcc tccgagactc tgctgggaat    120

gtaaagctgg gggactttgg ggccagcaaa cgcctgcaga cgatctgtat gtcggggacg    180

ggcatgcgct ccgtcactgg cacaccctac tggatgagcc ctgaggtgat cagcggcgag    240

ggctatggaa ggaaagcaga cgtgtggagc ctgggctgca ctgtggtgga gatgctgaca    300

gagaaaccac cgtgggcaga gtatgaagct atggccgcca tcttcaagat tgccacccag    360

cccaccaatc ctcagctgcc ctcccacatc tctgaacatg gccgggactt cctgaggcgc    420

atttttgtgg aggctcgcca gagaccttca gctgaggagc tgctcacaca ccactttgca    480

cagctcatgt actgagctct cacggccaca cagctgccgg tcgccctttg ctgcatggca    540

gggggctgct gctgggctca gtgaagttgc tgcttctccc aggcaaggct gtggaccatg    600

gagtggcagc ccagccagcg tcggtctgtg ccccttccgc cactggggct cagagccggg    660

ggtggggtgg ctgcagcctc aggactggga gcccccagcc tgtcagatcc aggagctcca    720

gtgtcctgag ctcagcgtgg aggggtaggg gctgggaaca gggtgcaagg aagccggggg    780

ccccaccccc gggggagtgg cctgaccctg caattggcac caagcccaaa gggccggtgg    840

cccaaaaatg accccagggt ataaaaagtg tattttcctc caaagggatt ttgtttttcc    900

ctccagggcc gggggccccc agggatttct ggggtggaac actccccaaa aacggggaaa    960

acccccaccc cctaacatgt naggaaaacc cccgactccc ccccaagaac ccgggagtac   1020

cccaccgccc tttccnnaaa aaggcccaac ttccccccca tttcccaaag ggaaaacctc   1080

ctggccccgc ccactccccc ncgggcccnn ggcaaccgcc ccctccccca cccnccncac   1140

nccccccctc tcccnccccn gggnnntccc nccnnnnnag ccgnccccnc              1190


<210>  470
<211>  1253
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (945)..(945)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (957)..(957)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (962)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (983)..(983)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1008)..(1008)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1012)..(1012)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1018)..(1018)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1021)..(1021)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1030)..(1031)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1042)..(1042)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1053)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1065)..(1065)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1095)..(1095)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1124)..(1124)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1130)..(1130)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1140)..(1140)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1144)..(1144)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1146)..(1146)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1151)..(1151)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1154)..(1154)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1158)..(1159)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1161)..(1161)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1175)..(1175)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1185)..(1185)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1195)..(1195)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1203)..(1204)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1206)..(1206)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1220)..(1221)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1230)..(1230)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1244)..(1244)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1250)..(1250)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1252)..(1253)
<223>  n is a, c, g, or t

<400>  470
aatagagaga ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gcggacgcgt gggctcgaaa agataaagac    120

caaaggaagc aacaggcaat gtggcgagtg ccctctgatt taaagatgct aaaaagactc    180

aaaactcaaa tggccgaagt tcgatgtatg aaaactgatg taaagaatac actttcagaa    240

ataaaaagca gcagtgctgc ttctggagac atgcagacaa gccttttttc tgctgaccag    300

gcagctctgg ctgcatgtgg aactgaaaac tctggcagat tgcaggattt gggaatggaa    360

ctcctggcaa agtcatcagt tgccaattgt tacatacgaa actccacaaa taagaagagt    420

aattcgccca agccagctcg atccagtgta gcaggtagtc tatcacttcg aagagcagtg    480

gaccctggag aaaatagtcg ttcaaaggga gactgtcaga ctctgtctga aggctcccca    540

ggaagctctc agtctgggag caggcacagt tctccccgag ccttgataca tggcagtatc    600

ggtgatattc tgccaaaaac tgaagaccgg cagtgtaaag ctttggattc agatgctgtt    660

gtggttgcag ttttcagtgg cttgcctgcg gttgagaaaa ggaggaaaat ggtcaccttg    720

ggggctaatg ctaaaggagg tcatctggaa ggactgcaga tgactgattt ggaaaataat    780

tctgaaactg gagagttaca gcctgtacta cctgaaggag cttcagctgc ccctgaagaa    840

ggaatgagta gcgacagtga cattgaatgt gacactgaga atgaggagca ggaagagcat    900

accagtgtgg gcgggtttcc cgactccttc atggtcatga cacanccccg gatgaanata    960

cncattccag ttttcctgat ggngaacaaa taggccctga aaatctcncc tncatacnga   1020

ntgaaaaaan nggaaggtan tngccaaatc aanaaactga cttgncaagc taccttgacc   1080

ctgaatttgc tgaantgggg cccaaattgt ctccgccaaa aacnaaattn ggcctttttn   1140

ttcntntccc nccngaanna naatttgaaa cggtnggagg gggcnctttt ttctnaaacc   1200

ccnntnttcc tgggaaaacn nttgggaaan tttttttatg ggangaaaan ann          1253


<210>  471
<211>  933
<212>  DNA
<213>  Homo sapiens

<400>  471
tatgagaggt cgcatcacca tcaccatcac ggatcctatt taggtgacac tatagaatcg     60

tcgacccacg cgtccgctgg tatcagcgat gtttttgcta aaaatgatct tgctgttgtg    120

gatgtcagaa ttggtatgac taggaaattt ggttatgtgg attttgaatc tgctgaagac    180

ctggagaaag cgttggaact cactggtttg aaagtctttg gcaatgaaat taaactagag    240

aaaccaaaag gaaaagacag taagaaagag cgagatgcga gaacactttt ggctaaaaat    300

ctcccttaca aagtcactca ggatgaattg aaagaagtgt ttgaagatgc tgcggagatc    360

agattagtca gcaaggatgg gaaaagtaaa gggattgctt atattgaatt taagacagaa    420

gctgatgcag agaaaacctt tgaagaaaag cagggaacag agatcgatgg gcgatctatt    480

tccctgtact atactggaga gaaaggtcaa aatcaagact atagaggtgg aaagaatagc    540

acttggagtg gtgaatcaaa aactctggtt ttaagcaacc tctcctacag tgcaacagaa    600

gaaactcttc aggaagtatt tgagaaagca acttttatca aagtacccca gaaccaaaat    660

ggcaaatcta aagggtatgc atttatagag tttgcttcat tcgaagacgc taaagaagct    720

ttaaattcct gtaataaaag ggaaattgag ggcagagcaa tcaggctgga gttgcaagga    780

cccaggggat cacctaatgc cagaagccag ccatccaaaa ctctgtttgt caaaggcctg    840

tctgaggata ccactgaaga gacattaaag gagtcatttg acggctccgt tcgggcaagg    900

atagttactg accgggaaac tgggtcctcc aaa                                 933


<210>  472
<211>  656
<212>  DNA
<213>  Homo sapiens

<400>  472
catcaccatc accatcacgg atcctattta ggtgacacta tagaatcgtc gacccacgcg     60

tccgcccttg ggtaccatgt ctaccctacc tgtaggaaca catccgggat tctaggattt    120

tctgtcactg tggggactca ggcaaccaaa tacaattctg aagttgttga taagaagata    180

gaagagtttc tttctagctt tgaggagaag attgagaacc tcactgaaga ggcattcaac    240

acccaggtca cagctctcat caagctgaag gagtgtgagg atacccacct tggggaggag    300

gtggatagga actggaatga agtggttaca cagcagtacc tctttgaccg ccttgcccac    360

gagattgaag cactgaagtc attctcaaaa tcagacctgg tcaactggtt caaggcccat    420

agagggccag gaagtaaaat gctcagcgtt catgttgttg gatatgggaa gtatgaactg    480

gaagaggatg gtaccccttc tagtgaggat tcaaattctt cttgtgaagt gatgcagctg    540

acctacctgc caacctctcc tctgctggca gattgtatca tccccattac tgatatcagg    600

gctttcacaa caacactcaa ccttctcccc taccataaaa tagtcaaata aataaa        656


<210>  473
<211>  979
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (6)..(11)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (14)..(14)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (526)..(526)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (637)..(637)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (639)..(639)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (671)..(671)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (707)..(707)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (732)..(732)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (734)..(734)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (746)..(746)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (773)..(773)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (788)..(788)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (790)..(790)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (792)..(792)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (800)..(800)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (810)..(810)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (823)..(823)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (835)..(835)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (838)..(838)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (844)..(844)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (848)..(848)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (869)..(869)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (883)..(883)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (886)..(886)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (894)..(894)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (902)..(902)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (906)..(906)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (918)..(918)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (923)..(923)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (931)..(931)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (936)..(936)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (939)..(939)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (941)..(941)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (944)..(944)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (946)..(946)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (949)..(949)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (974)..(975)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (979)..(979)
<223>  n is a, c, g, or t

<400>  473
antccnnnnn ngantagaga aattactatg agaggatcgc atcaccatca ccatcacgga     60

tcctatttag gtgacactat agaatcgtcg acccacgcgt ccggcggacc ccagagagcc    120

ctgagcagcc ccaccgccgc cgccggccta gttaccatca caccccggga ggagccgcag    180

ctgccgcagc cggccccagt caccatcacc gcaaccatga gcagcgaggc cgagacccag    240

cagccgcccg ccgccccccc cgccgccccc gccctcagcg ccgccgacac caagcccggc    300

actacgggca gcggcgcagg gagcggtggc ccgggcggcc tcacatcggc ggcgcctgcc    360

ggcggggaca agaaggtcat cgcaacgaag gttttgggaa cagtaaaatg gttcaatgta    420

aggaacggat atggtttcat caacaggaat gacaccaagg aagatgtatt tgtacaccag    480

actgccataa agaagaataa ccccaggaag taccttcgca gtgtangaga tggagagact    540

gtggagtttg atgttgttga aggagaaaag ggtgcggagg cagcaaatgt tacaggtcct    600

ggtggtgttc cagttcaagg cagtaaatat gcagcananc gtaaccatta tagacgctat    660

ccacgtcgta ngggtccttc cacgcaatta ccagcaaaat ttaccanaat agtgagagtg    720

gggaaaaaaa cnangggatt ggaaantgct tccgaaggcc aagcccaaca aangccgggc    780

cctaccgnan gngaaggttn cccaccttan taacatgcgg ganacccttt ggggngtnca    840

aacncaanta ttccaaccct tctttttcng ggaaaaattt atnganggtt gttnaaaaac    900

cngggntgta ggaaaaanaa ggnttaaacc ntttgnggna naantnttnt ttttcggggg    960

aattaaaaac cccnnattn                                                 979


<210>  474
<211>  1160
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (768)..(768)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (874)..(874)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (881)..(881)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (885)..(885)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (898)..(898)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (962)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (982)..(982)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (991)..(991)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1024)..(1024)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1028)..(1028)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1033)..(1033)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1036)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1054)..(1054)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1058)..(1058)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1060)..(1060)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1062)..(1062)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1105)..(1105)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1112)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1118)..(1118)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1122)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1125)..(1125)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1133)..(1133)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1143)..(1143)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1160)
<223>  n is a, c, g, or t

<400>  474
aatagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gcccacgcgt ccggcgtctt cccgagccag    120

tgtgctgagc tctccgcgtc gcctctgtcg cccgcgcctg gcctaccgcg gcactcccgg    180

ctgcacgctc tgcttggcct cgccatgccg gtggacctca gcaagtggtc cgggcccttg    240

agcctgcaag aagtggacga gcagccgcag cacccgctgc atgtcaccta cgccggggcg    300

gcggtggacg agctgggcaa agtgctgacg cccacccagg ttaagaatag acccaccagc    360

atttcgtggg atggtcttga ttcagggaag ctctacacct tggtcctgac agacccggat    420

gctcccagca ggaaggatcc caaatacaga gaatggcatc atttcctggt ggtcaacatg    480

aagggcaatg acatcagcag tggcacagtc ctctccgatt atgtgggctc ggggcctccc    540

aagggcacag gcctccaccg ctatgtctgg ctggtttacg agcaggacag gccgctaaag    600

tgtgacgagc ccatcctcag caaccgatct ggagaccacc gtggcaaatt caaggtggcg    660

tccttccgta aaaagtatga gctcagggcc ccggtggctg gcacgtgtta ccaggccgag    720

tgggatgact atgtgcccaa actgtacgag cagctgtctg ggaagtangg ggttagcttg    780

gggacctgaa ctgtcctgga ggccccaagc catgttcccc agttcagtgt tgcatgtata    840

aataaaattt ctcctcttcc tgcccccctt tggnaatggg ntganaacct gaaccaantc    900

aaatggtagt tgaagggtga ctttttcctg ctggcctggc cttttataat tttacncact    960

cnctctgatt ttatgttttg ancaaatttg naactttcat tttggggggg aattttggta   1020

atgnggangg ggntcntcaa attattaaat ctgnaaanan cnaacccaaa atgtaaaaaa   1080

aaaaaaactt gggggaaaaa aaaanagttn cnccattnga nnaancaaac ctncaaaaaa   1140

atnttttatg gaaaggtttn                                               1160


<210>  475
<211>  1596
<212>  DNA
<213>  Homo sapiens

<400>  475
atgtcgaagc cccatagtga agccgggact gccttcattc agacccagca gctgcacgca     60

gccatggctg acacattcct ggagcacatg tgccgcctgg acattgattc accacccatc    120

acagcccgga acactggcat catctgtacc attggcccag cttcccgatc agtggagacg    180

ttgaaggaga tgattaagtc tggaatgaat gtggctcgtc tgaacttctc tcatggaact    240

catgagtacc atgcggagac catcaagaat gtgcgcacag ccacggaaag ctttgcttct    300

gaccccatcc tctaccggcc cgttgctgtg gctctagaca ctaaaggacc tgagatccga    360

actgggctca tcaagggcag cggcactgca gaggtggagc tgaagaaggg agccactctc    420

aaaatcacgc tggataacgc ctacatggaa aagtgtgacg agaacatcct gtggctggac    480

tacaagaaca tctgcaaggt ggtggaagtg ggcagcaaga tctacgtgga tgatgggctt    540

atttctctcc aggtgaagca gaaaggtgcc gacttcctgg tgacggaggt ggaaaatggt    600

ggctccttgg gcagcaagaa gggtgtgaac cttcctgggg ctgctgtgga cttgcctgct    660

gtgtcggaga aggacatcca ggatctgaag tttggggtcg agcaggatgt tgatatggtg    720

tttgcgtcat tcatccgcaa ggcatctgat gtccatgaag ttaggaaggt cctgggagag    780

aagggaaaga acatcaagat tatcagcaaa atcgagaatc atgagggggt tcggaggttt    840

gatgaaatcc tggaggccag tgatgggatc atggtggctc gtggtgatct aggcattgag    900

attcctgcag agaaggtctt ccttgctcag aagatgatga ttggacggtg caaccgagct    960

gggaagcctg tcatctgtgc tactcagatg ctggagagca tgatcaagaa gccccgcccc   1020

actcgggctg aaggcagtga tgtggccaat gcagtcctgg atggagccga ctgcatcatg   1080

ctgtctggag aaacagccaa aggggactat cctctggagg ctgtgcgcat gcagcacctg   1140

attgcccgtg aggcagaggc tgccatctac cacttgcaat tatttgagga actccgccgc   1200

ctggcgccca ttaccagcga ccccacagaa gccaccgccg tgggtgccgt ggaggcctcc   1260

ttcaagtgct gcagtggggc cataatcgtc ctcaccaagt ctggcaggtc tgctcaccag   1320

gtggccagat accgcccacg tgcccccatc attgctgtga cccggaatcc ccagacagct   1380

cgtcaggccc acctgtaccg tggcatcttc cctgtgctgt gcaaggaccc agtccaggag   1440

gcctgggctg aggacgtgga cctccgggtg aactttgcca tgaatgttgg caaggcccga   1500

ggcttcttca agaagggaga tgtggtcatt gtgctgaccg gatggcgccc tggctccggc   1560

ttcaccaaca ccatgcgtgt tgttcctgtg ccgtga                             1596


<210>  476
<211>  1289
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (889)..(889)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (942)..(942)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (944)..(944)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (957)..(957)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (969)..(969)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (980)..(980)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (988)..(988)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (992)..(992)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1025)..(1025)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1033)..(1033)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1055)..(1055)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1066)..(1066)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1101)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1108)..(1108)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1120)..(1120)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1122)..(1122)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1125)..(1125)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1128)..(1128)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1134)..(1134)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1146)..(1146)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1151)..(1151)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1159)..(1159)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1166)..(1166)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1172)..(1172)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1177)..(1177)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1179)..(1179)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1184)..(1184)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1191)..(1191)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1195)..(1195)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1199)..(1200)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1211)..(1211)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1214)..(1214)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1217)..(1217)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1237)..(1237)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1247)..(1247)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1257)..(1257)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1261)..(1261)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1269)..(1269)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1277)..(1277)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1281)..(1281)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1286)..(1286)
<223>  n is a, c, g, or t

<400>  476
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc ccacgcgtcc gatttggatg ggaaacatgt    120

ggtgtttggc caagtaatta aaggaatagg agtggcaagg atattggaaa atgtggaagt    180

gaaaggtgaa aaacctgcta aattgtgcgt tattgcagaa tgtggagaat tgaaggaagg    240

agatgacggg ggaatattcc caaaagatgg ctctggcgac agtcatccag atttccctga    300

ggatgcggat atagatttaa aagatgtaga taaaatttta ttaataacag aagacttaaa    360

aaacattgga aatacttttt tcaaatccca gaactgggag atggctatta aaaaatatgc    420

agaagtttta agatacgtgg acagttcaaa ggctgttatt gagacagcag atagagccaa    480

gctgcaacct atagctttaa gctgtgtact gaatattggt gcttgtaaac tgaagatgtc    540

aaattggcag ggagcaattg acagttgttt agaggctctt gaactagacc catcaaatac    600

caaagcattg taccgcagag ctcaaggatg gcaaggatta aaagaatatg atcaagcatt    660

ggctgatctt aagaaagctc aggggatagc accagaagat aaagctatcc aggcagaatt    720

gctgaaagtc aaacaaaaga taaaggcaca gaaagataaa gagaaggcag tatatgcaaa    780

aatgtttgct tagaaaggat tcagttttgc ttattgtgtg ttgattgtat aaatgcaata    840

agaaaatgta aaggtttttg tctatgaata tgatccctaa tgtgtttcnt ttgacacctt    900

agttccttac tgtttacagt ttaggagtac tgataggggg tncntgctta ataaacntgt    960

cccaatacng taagtaaagn ggttttgntt gnttcctttg aaatggagtc ttgctctgtc   1020

ccccnggctg gangcggggg cgcaatcccg gctcnctgca tccccnggcc ccccggggtc   1080

caagcaattc ccccgccccc ncctcccnag tagctgggan tnacnggncc cggncccccc   1140

cccccnccta ntttttgtnt ttttanaaaa anggggntnc cccnaattgg ncccncccnn   1200

tgggcctgaa nccntgnccc tgggaccccc ccccccntgg ccccccnaag ggggggnaaa   1260

ngggggganc ccccccnccc nccccnaaa                                     1289


<210>  477
<211>  913
<212>  DNA
<213>  Homo sapiens

<400>  477
catcaccatc accatcacgg atcctattta ggtgacacta tagaatcgtc gacccacgcg     60

tccgcccacg cgtccgcaat cggcactggg tatgacctgt cagcctctac attctctcct    120

gacggaagag tttttcaagt tgaatatgct atgaaggctg tggaaaatag tagtacagct    180

attggaatca gatgcaaaga tggtgttgtc tttggggtag aaaaattagt cctttctaaa    240

ctttatgaag aaggttccaa caaaagactt tttaatgttg atcggcatgt tggaatggca    300

gtagcaggtt tgttggcaga tgctcgttct ttagcagaca tagcaagaga agaagcttcc    360

aacttcagat ctaactttgg ctacaacatt ccactaaaac atcttgcaga cagagtggcc    420

atgtatgtgc atgcatatac actctacagt gctgttagac cttttggctg cagtttcatg    480

ttagggtctt acagtgtgaa tgacggtgcg caactctaca tgattgaccc atcaggtgtt    540

tcatacggtt attggggctg tgccatcggc aaagccaggc aagctgcaaa gacggaaata    600

gagaagcttc agatgaaaga aatgacctgc cgtgatatcg ttaaagaagt tgcaaaaata    660

atttacatag tacatgacga agttaaggat aaagcttttg aactagaact cagctgggtt    720

ggtgaattaa ctaatggaag acatgaaatt gttccaaaag atataagaga agaagcagag    780

aaatatgcta aggaatctct gaaggaagag atgaatcaga tgatgataat atgtaacatt    840

tactccagca tctattgtat tttaaatttc tactccagtc caatgtaact atttagccct    900

ggattataca tac                                                       913


<210>  478
<211>  1013
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (763)..(763)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (786)..(786)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (802)..(802)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (860)..(860)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (875)..(875)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (893)..(893)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (905)..(905)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (931)..(931)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (944)..(945)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (948)..(948)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (983)..(983)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (990)..(990)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (992)..(992)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<400>  478
nttagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gcccacgcgt ccggcaagat ggcgggtgaa    120

aaagttgaga agccagatac taaagagaag aaacccgaag ccaagaaggt tgatgctggt    180

ggcaaggtga aaaagggtaa cctcaaagct aaaaagccca agaaggggaa gccccattgc    240

agccgcaacc ctgtccttgt cagaggaatt ggcaggtatt cccgatctgc catgtattcc    300

agaaaggcca tgtacaagag gaagtactca gccgctaaat ccaaggttga aaagaaaaag    360

aaggagaagg ttctcgcaac tgttacaaaa ccagttggtg gtgacaagaa cggcggtacc    420

cgggtggtta aacttcgcaa aatgcctaga tattatccta ctgaagatgt gcctcgaaag    480

ctgttgagcc acggcaaaaa acccttcagt cagcacgtga gaaaactgcg agccagcatt    540

acccccggga ccattctgat catcctcact ggacgccaca ggggcaagag ggtggttttc    600

ctgaagcagc tggctagtgg cttattactt gtgactggac ctctggtcct caatcgagtt    660

cctctacgaa gaacacacca gaaatttgtc attgccactt caaccaaaaa tcgatatcag    720

caatgtaaaa atcccaaaac atcttactga tgcttacttc agnaagaaga agctgcggaa    780

gcccanacac caggaaggtg anatcttcga cacagaaaaa gagaaatatg agattacgga    840

accagcgcaa gattgatcan aaagctgtgg actcncaaat ttttaccaaa atncaaagct    900

attcntcagc ctccagggct acctgcgatt nggttttgct ctgnnaangg aatttttcct    960

cccaaatttg gtgtttctaa atntcttaan ancctattta aatacntgac tac          1013


<210>  479
<211>  814
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (655)..(655)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (745)..(745)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (756)..(756)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (784)..(784)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (791)..(791)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (794)..(794)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (796)..(796)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (811)..(811)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (814)..(814)
<223>  n is a, c, g, or t

<400>  479
tcttaangag gagaattaac tatgagagga tcgcatcacc atcaccatca cggatcctat     60

ttaggtgaca ctatagaatc gtcgacccac gcgtccgcca tggagggtgt agaagagaag    120

aagaaggagg ttcctgctgt gccagaaacc cttaagaaaa agcgaaggaa tttcgcagag    180

ctgaagatca agcgcctgag aaagaagttt gcccaaaaga tgcttcgaaa ggcaaggagg    240

aagcttatct atgaaaaagc aaagcactat cacaaggaat ataggcagat gtacagaact    300

gaaattcgaa tggcgaggat ggcaagaaaa gctggcaact tctatgtacc tgcagaaccc    360

aaattggcgt ttgtcatcag aatcagaggt atcaatggag tgagcccaaa ggttcgaaag    420

gtgttgcagc ttcttcgcct tcgtcaaatc ttcaatggaa cctttgtgaa gctcaacaag    480

gcttcgatta acatgctgag gattgtagag ccatatattg catgggggta ccccaatctg    540

aagtcagtaa atgaactaat ctacaagcgt ggttatggca aaatcaataa gaagcgaatt    600

gctttgacag ataacgcttt gattgctcga tctcttggta aatacggcat catcntgcat    660

gggaggattt gattcatgag atctatactg ttggaaaacg cttcaaagag gcaaataact    720

tcctgtggcc cttcaaattg tcttnctccc cgaggnggaa tgaagaaaaa gacacccctt    780

tttngtaaaa nggngnagat gctggccaaa nggn                                814


<210>  480
<211>  945
<212>  DNA
<213>  Homo sapiens

<400>  480
tatgagagga tcgcatcacc atcaccatca cggatcctat ttaggtgaca ctatagaatc     60

gtcgacccac gcgtccgcgc cgcccaagat gccgaaagga aagaaggcca agggaaagaa    120

ggtggctccg gccccagctg tcgtgaagaa gcaggaggct aagaaagtgg tgaatcccct    180

gtttgagaaa aggcctaaga attttggcat tggacaggac atccagccca aaagagacct    240

cacccgcttt gtgaaatggc cccgctatat caggttgcag cggcagagag ccatcctcta    300

taagcggctg aaagtgcctc ctgcgattaa ccagttcacc caggccctgg accgccaaac    360

agctactcag ctgcttaagc tggcccacaa gtacagacca gagacaaagc aagagaagaa    420

gcagagactg ttggcccggg ccgagaagaa ggctgctggc aaaggggacg tcccaacgaa    480

gagaccacct gtccttcgag caggagttaa caccgtcacc accttggtgg agaacaagaa    540

agctcagctg gtggtgattg cacacgacgt ggatcccatc gagctggttg tcttcttgcc    600

tgccctgtgt cgtaaaatgg gggtccctta ctgcattatc aagggaaagg caagactggg    660

acgtctagtc cacaggaaga cctgcaccac tgtcgccttc acacaggtga actcggaaga    720

caaaggcgct ttggctaagc tggtggaagc tatcaggacc aattacaatg acagatacga    780

tgagatccgc cgtcactggg gtggcaatgt cctgggtcct aagtctgtgg ctcgtatcgc    840

caagctcgaa aaggcaaagg ctaaagaact tgccactaaa ctgggttaaa tgtacactgt    900

tgagttttct gtacataaaa ataattgaaa taatacaaat tttcc                    945


<210>  481
<211>  875
<212>  DNA
<213>  Homo sapiens

<400>  481
tatgagagga tcgcatcacc atcaccatca cggatcctat ttaggtgaca ctatagaatc     60

gtcgacccac gcgtccggaa caggacccgt cgccatgggc cgtgtgatcc gtggacagag    120

gaagggcgcc gggtctgtgt tccgcgcgca cgtgaagcac cgtaaaggcg ctgcgcgcct    180

gcgcgccgtg gatttcgctg agcggcacgg ctacatcaag ggcatcgtca aggacatcat    240

ccacgacccg ggccgcggcg cgcccctcgc caaggtggtc ttccgggatc cgtatcggtt    300

taagaagcgg acggagctgt tcattgccgc cgagggcatt cacacgggcc agtttgtgta    360

ttgcggcaag aaggcccagc tcaacattgg caatgtgctc cctgtgggca ccatgcctga    420

gggtacaatc gtgtgctgcc tggaggagaa gcctggagac cgtggcaagc tggcccgggc    480

atcagggaac tatgccaccg ttatctccca caaccctgag accaagaaga cccgtgtgaa    540

gctgccctcc ggctccaaga aggttatctc ctcagccaac agagctgtgg ttggtgtggt    600

ggctggaggt ggccgaattg acaaacccat cttgaaggct ggccgggcgt accacaaata    660

taaggcaaag aggaactgct ggccacgagt acggggtgtg gccatgaatc ctgtggagca    720

tccttttgga ggtggcaacc accagcacat cggcaagccc tccaccatcc gcagagatgc    780

ccctgctggc cgcaaagtgg gtctcattgc tgcccgccgg actggacgtc tccggggaac    840

caagactgtg caggagaaag agaactagtg ctgag                               875


<210>  482
<211>  1077
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (749)..(749)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (830)..(830)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (855)..(855)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (857)..(857)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (889)..(889)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (919)..(919)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (922)..(922)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (943)..(943)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (945)..(945)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (967)..(967)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (972)..(972)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (983)..(983)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1000)..(1000)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1003)..(1003)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1012)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1027)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1054)..(1077)
<223>  n is a, c, g, or t

<400>  482
naatagagaa attaactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgcggacgc gtgggcaaaa caccaaatgg    120

cggatgacgc cggtgcagcg ggggggcccg ggggccctgg tggccctggg atggggaacc    180

gcggtggctt ccgcggaggt ttcggcagtg gcatccgggg ccggggtcgc ggccgtggac    240

ggggccgggg ccgaggccgc ggagctcgcg gaggcaaggc cgaggataag gagtggatgc    300

ccgtcaccaa gttgggccgc ttggtcaagg acatgaagat caagtccctg gaggagatct    360

atctcttctc cctgcctatt aaggaatcag agatcattga tttcttcctg ggggcctctc    420

tcaaggatga ggttttgaag attatgccag tgcagaagca gacccgtgcc ggccagcgca    480

ccaggttcaa ggcatttgtt gctatcgggg actacaatgg ccacgtcggt ctgggtgtta    540

agtgctccaa ggaggtggcc accgccatcc gtggggccat catcctggcc aagctctcca    600

tcgtccccgt gcgcagaggc tactggggga acaagatcgg caagccccac actgtccctt    660

gcaaggtgac aggccgctgc ggctctgtgc tggtacgcct catccctgca cccaggggca    720

ctggcatcgt ctccgcacct gtgcctaana agctgctcat gatggctggt atcgatgact    780

gctacacctc agcccggggc tgcactgcca ccctgggcaa cttcgccaan gccacctttg    840

atgccatttt ctaanancta cagctacctg aacccccgac ctctggaang aaactgtatt    900

caccaagtct ccctatcang anttcactga ccacctcgtc aananccaca ccaaaatctc    960

cgtgcancgg antcaggctc canctgtggc tacaaaatan ggnttttttt nncaaaaaaa   1020

ataaanntga attaaccgtg aaaaaaaaaa aaannnnnnn nnnnnnnnnn nnnnnnn      1077


<210>  483
<211>  846
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (708)..(708)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (738)..(738)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (781)..(781)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (785)..(785)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (788)..(788)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (812)..(812)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (816)..(816)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (822)..(822)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (836)..(836)
<223>  n is a, c, g, or t

<400>  483
taagaggaga attaactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgctctgac cagcaccatg gcggttggca    120

agaacaagcg ccttacgaaa ggcggcaaaa agggagccaa gaagaaagtg gttgatccat    180

tttctaagaa agattggtat gatgtgaaag cacctgctat gttcaatata agaaatattg    240

gaaagacgct cgtcaccagg acccaaggaa ccaaaattgc atctgatggt ctcaagggtc    300

gtgtgtttga agtgagtctt gctgatttgc agaatgatga agttgcattt agaaaattca    360

agctgattac tgaagatgtt cagggtaaaa actgcctgac taacttccat ggcatggatc    420

ttacccgtga caaaatgtgt tccatggtca aaaaatggca gacaatgatt gaagctcacg    480

ttgatgtcaa gactaccgat ggttacttgc ttcgtctgtt ctgtgttggt tttactaaaa    540

aacgcaacaa tcagatacgg aagacctctt atgctcagca ccaacaggtc cgccaaatcc    600

ggaagaagat gatggaaatc atgacccgag aggtgcagac aaatgacttg aaaaaaagtg    660

gtcaataaat tgattccaga cagcattgga aaagacatag aaaagggntt gccaatctat    720

ttatcctctc catgatgnct tcgttagaaa agtaaaaatg ctgaagaaac cccaagtttg    780

naatnggnaa agctcatgga gcttcatggg gnaagncagt anttctggaa aagccnctgg    840

ggacga                                                               846


<210>  484
<211>  844
<212>  DNA
<213>  Homo sapiens

<400>  484
ctatgagagg acgcatcacc atcaccatca cggatcctat ttaggtgaca ctatagaatc     60

gtcgactctg gaccttggct gtcactcagt taaaagagcc caggagagtc agattgattt    120

cctaaattca gtaatagtgg accttcaaag gaagaatcaa gacctcaaga tgaaggtgga    180

gatgatgtca gaagcagccc tgaatgggaa cggggatgac ctaaacaatt atgacagtga    240

tgatcaggag aaacagtcca agaagaaacc tcgcctcttc tgtgacattt gtgactgctt    300

tgatctccac gacacagagg attgtcctac ccaggcacag atgtcagagg accctcccca    360

ttccacacac catggcagtc ggggtgagga acgcccatac tgtgaaatct gtgagatgtt    420

tggacactgg gccaccaact gcaatgacga cgaaaccttc tgatgaagcc tccagtggag    480

aactgggctt gctcagacgc actcgcattg acacaacgta acaccagcat tgtgtgtgca    540

gacttcaaga gaactcatgt tattttttaa ccccgtcaac agatctagga aaatattttg    600

atcttcaaca aattgccctt tactctcccc gtatgagtta gaataataaa tatttagtag    660

gtgagttttc acctcgaatt ctgttttctt gatttttacg tttgaagaca tagcagcaga    720

tgccattaca attattgacc ccccgacctt gtataaaacc cctaccctca cataccttag    780

tcagtgaact taattgagcc gtgcctttcc cagttgcccc gatctttcgg gccgaattgc    840

ttat                                                                 844


<210>  485
<211>  435
<212>  DNA
<213>  Homo sapiens

<400>  485
atggcctcat tcctcctgtt ctcccagttt gctttccact taagacaaag ccttgtctat     60

gtggggggcg gggaccgggg aaagagggag gctgaaatgt ttattctgct tctcccgtgt    120

ttcatgccat ctcgcgtccc ccttcctgca catgggtgtg aatgcacaca catacgcgta    180

cacacaggac ttggtctgct ggcctggcct cttctgccca ggtgggttgg aacacgtttg    240

ctgcctgagc ctgtgccact gagcatgtta ggtggagcag ttggtgtggc acgtgcgggg    300

tgttggcacc ggaggcatgg aaaagcacag gctgtactgc caggctgcga tgcgtgctgg    360

cccccgcaca ggctcctgtg tgcagggact gattcctcag cacacgaggc ttccacaacc    420

cagtctgctc catag                                                     435


<210>  486
<211>  795
<212>  DNA
<213>  Homo sapiens

<400>  486
atggagtctg gcaagacggc ttctcccaag agcatgccga aagatgcaca gatgatggca     60

caaatcctga aggatatggg gattacagaa tatgagccaa gagttataaa tcagatgttg    120

gagtttgcct tccgatatgt gaccacaatt ctagatgatg caaaaattta ttcaagccat    180

gctaagaaag ctactgttga tgcagatgat gtgcgattgg caatccagtg ccgcgctgat    240

cagtctttta cctctcctcc cccaagagat tttttattag atattgcaag gcaaagaaat    300

caaacccctt tgccattgat caagccatat tcaggtccta ggttgccacc tgatagatac    360

tgcttaacag ctccaaacta taggctgaaa tctttacaga aaaaggcatc aacttctgcg    420

ggaagaataa cagtcccgcg gttaagtgtt ggttcagtta ctagcagacc aagtactccc    480

acactaggca caccaacccc acagaccatg tctgtttcaa ctaaagtagg gactcccatg    540

tccctcacag gtcaaaggtt tacagtacag atgcctactt ctcagtctcc agctgtaaaa    600

gcttcaattc ctgcaacctc agcagttcag aatgttctga ttaatccatc attaatcggg    660

tccaaaaaca tttttattac cactaatatg atgtcatcac aaaatactgc caatgaatca    720

tcaaatgcat tgaaaagaaa acgtgaagat gatgatgatg acgatgatga tgatgatgac    780

tatgataatc tgtaa                                                     795


<210>  487
<211>  429
<212>  DNA
<213>  Homo sapiens

<400>  487
atggcctccg gtaacgcgcg catcggaaag ccagcccctg acttcaaggc cacagcggtg     60

gttgatggcg ccttcaaaga ggtgaagctg tcggactaca aagggaagta cgtggtcctc    120

tttttctacc ctctggactt cacttttgtg tgccccaccg agatcatcgc gttcagcaac    180

cgtgcagagg acttccgcaa gctgggctgt gaagtgctgg gcgtctcggt ggactctcag    240

ttcacccacc tggcttggta tgagcagggg ccaaagaggg aggttgcagc taagctcaca    300

ccctcaggtc ctagcagtgt ggcttcgtgg ccattgctca acctctggaa cctgcgtttc    360

cccatcgtga aaataatgga aacattgccg cccaagtctt taaggatgat gacagtaatt    420

agcatttga                                                            429


<210>  488
<211>  1221
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (911)..(911)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (958)..(958)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (981)..(981)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (983)..(983)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1004)..(1004)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1011)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1044)..(1044)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1055)..(1055)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1057)..(1057)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1063)..(1063)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1075)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1082)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1091)..(1091)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1095)..(1095)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1108)..(1108)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1116)..(1116)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1129)..(1129)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1138)..(1138)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1143)..(1143)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1147)..(1147)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1149)..(1149)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1152)..(1152)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1159)..(1159)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1172)..(1172)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1179)..(1179)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1181)..(1181)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1187)..(1187)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1190)..(1190)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1194)..(1194)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1196)..(1196)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1200)..(1200)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1202)..(1202)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1205)..(1205)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1217)..(1217)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1220)..(1220)
<223>  n is a, c, g, or t

<400>  488
tagagaaatt anctatgaga ggatcgcatc accatcacca tcacggatcc tatttaggtg     60

acactcctag aatcgtcgac ccacgcgtcc gcaaatctga aaactcacat taagtctaaa    120

catggtaaca atttgccata taaatgtgag cattgtcccc aagcatttgg tgatgagagg    180

gagcttcaac gccatctgga tttgtttcaa ggacataaga cacaccagtg tcctcattgt    240

gaccataaga gcaccaattc aagtgacctt aagcggcaca tcatatctgt ccatactaag    300

gattttcctc acaaatgtga ggtctgtgat aaaggttttc atcgtccttc tgagctcaaa    360

aagcatagtg atatccataa gggtaggaag attcatcagt gcaggcactg tgactttaaa    420

acatccgatc catttattct tagtggccat atcctttcag ttcatactaa agatcagcca    480

ttgaaatgta aaaggtgcaa gagaggattc agacaacaaa atgagctaaa aaaacatatg    540

aagacccata ctggaaggaa gatttaccaa tgtgagtatt gtgaatacag cactacagat    600

gcatctggct ttaaacgaca tgtgatatca atacatacaa aagactatcc acacaggtgt    660

gaattctgca agaagggatt ccgaagacca tcagaaaaaa atcagcatat tatgaggcac    720

cacaaagagg ctcttatgta ataagatcaa tataaagaaa gaagctattt aggagatatg    780

atatgctact tgggagaaaa ctctcactaa ctgtctcacc gggtttcaaa gcttgatact    840

aaaccatgac tttacattct ttgtattaaa gatcttaaaa tatttgaatt cacaggggat    900

cccatagccc nttgaaaatt actttaaaga atttaagaag ccctatagaa tggttacngg    960

aaaaccttct taagtatctg ngnaaaagta ttatatgcat actnaacctc ngaggggaaa   1020

gcaaagacaa aacttttttt gggntgatat gttananaca aangttttga aaanngaaaa   1080

cnttaattga nttanggngg tttggctnaa gcaagncaaa ccccttttnt gcaatttnaa   1140

aangggncng gnaaaaaang ggggccttcc cngcccctna nccttgngcn tttnantggn   1200

cnggnaatta attcccncan g                                             1221


<210>  489
<211>  708
<212>  DNA
<213>  Homo sapiens

<400>  489
atgaacatcc gcaatgcgag gccagaggac ctaatgaaca tgcagcactg caacctcctc     60

tgcctgcccg agaactacca gatgaaatac tacttctacc atggcctttc ctggccccag    120

ctctcttaca ttgctgagga cgagaatggg aagattgtgg ggtatgtcct ggccaaaatg    180

gaagaggacc cagatgatgt gccccatgga catatcacct cattggctgt gaagcgttcc    240

caccggcgcc tcggtctggc tcagaaactg atggaccagg cctctcgagc catgatagag    300

aacttcaatg ccaaatatgt ctccctgcat gtcaggaaga gtaaccgggc cgccctgcac    360

ctctattcca acaccctcaa ctttcagatc agtgaagtgg agcccaaata ctatgcagat    420

ggggaggacg cctatgccat gaagcgggac ctcactcaga tggccgacga gctgaggcgg    480

cacctggagc tgaaagagaa gggcaggcac gtggtgctgg gtgccatcga gaacaaggtg    540

gagagcaaag gcaattcacc tccgagctca ggagaggcct gtcgcgagga gaagggcctg    600

gctgccgagg atagtggtgg ggacagcaag gacctcagcg aggtcagcga gaccacagag    660

agcacagatg tcaaggacag ctcagaggcc tccgactcag cctcctag                 708


<210>  490
<211>  1725
<212>  DNA
<213>  Homo sapiens

<400>  490
atggaggcgt ctttggggat tcagatggat gagccaatgg ctttttctcc ccagcgtgac     60

cggtttcagg ctgaaggctc tttaaaaaaa aacgagcaga attttaaact tgcaggtgtt    120

aaaaaagata ttgagaagct ttatgaagct gtaccacagc ttagtaatgt gtttaagatt    180

gaggacaaaa ttggagaagg cactttcagc tctgtttatt tggccacagc acagttacaa    240

gtaggacctg aagagaaaat tgctctaaaa cacttgattc caacaagtca tcctataaga    300

attgcagctg aacttcagtg cctaacagtg gctggggggc aagataatgt catgggagtt    360

aaatactgct ttaggaagaa tgatcatgta gttattgcta tgccatatct ggagcatgag    420

tcgtttttgg acattctgaa ttctctttcc tttcaagaag tacgggaata tatgcttaat    480

ctgttcaaag ctttgaaacg cattcatcag tttggtattg ttcaccgtga tgttaagccc    540

agcaattttt tatataatag gcgcctgaaa aagtatgcct tggtagactt tggtttggcc    600

caaggaaccc atgatacgaa aatagagctt cttaaatttg tccagtctga agctcagcag    660

gaaaggtgtt cacaaaacaa atcccacata atcacaggaa acaagattcc actgagtggc    720

ccagtaccta aggagctgga tcagcagtcc accacaaaag cttctgttaa aagaccctac    780

acaaatgcac aaattcagat taaacaagga aaagacggaa aggagggatc tgtaggcctt    840

tctgtccagc gctctgtttt tggagaaaga aatttcaata tacacagctc catttcacat    900

gagagccctg cagtgaaact catgaagcag tcaaagactg tggatgtact gtctagaaag    960

ttagcaacaa aaaagaaggc tatttctacg aaagttatga atagtgctgt gatgaggaaa   1020

actgccagtt cttgcccagc tagcctgacc tgtgactgct atgcaacaga taaagtttgt   1080

agtatttgcc tttcaaggcg tcagcaggtt gcccctaggg caggtacacc aggattcaga   1140

gcaccagagg tcttgacaaa gtgccccaat caaactacag caattgacat gtggtctgca   1200

ggtgtcatat ttctttcttt gcttagtgga cgatatccat tttataaagc aagtgatgat   1260

ttaactgctt tggcccaaat tatgacaatt aggggatcca gagaaactat ccaagctgct   1320

aaaacttttg ggaaatcaat attatgtagc aaagaagttc cagcacaaga cttgagaaaa   1380

ctctgtgaga gactcagggg tatggattct agcactccca agttaacaag tgatatacaa   1440

gggcatgctt ctcatcaacc agctatttca gagaagactg accataaagc ttcttgcctc   1500

gttcaaacac ctccaggaca atactcaggg aattcattta aaaaggggga tagtaatagc   1560

tgtgagcatt gttttgatga gtataatacc aatttagaag gctggaatga ggtacctgat   1620

gaagcttatg acctgcttga taaacttcta gatctaaatc cagcttcaag aataacagca   1680

gaagaagctt tgttgcatcc attttttaaa gatatgagct tgtga                   1725


<210>  491
<211>  979
<212>  DNA
<213>  Homo sapiens

<400>  491
tatgagaggt cgcatcacca tcaccatcac ggatcctatt taggtgacac tatagaatcg     60

tcgacccacg cgtccgtgct tggaaagatg gcgtcccgca aggaaggtac cggctctact    120

gccacctctt ccagctccac cgccggcgca gcagggaaag gcaaaggcaa aggcggctcg    180

ggagattcag ccgtgaagca agtgcagata gatggccttg tggtattaaa gataatcaaa    240

cattatcaag aagaaggaca aggaactgaa gttgttcaag gagtgctttt gggtctggtt    300

gtagaagatc ggcttgaaat taccaactgc tttcctttcc ctcagcacac agaggatgat    360

gctgactttg atgaagtcca atatcagatg gaaatgatgc ggagccttcg ccatgtaaac    420

attgatcatc ttcacgtggg ctggtatcag tccacatact atggctcatt cgttacccgg    480

gcactcctgg actctcagtt tagttaccag catgccattg aagaatctgt cgttctcatt    540

tatgatccca taaaaactgc ccaaggatct ctctcactaa aggcatacag actgactcct    600

aaactgatgg aagtttgtaa agaaaaggat ttttcccctg aagcattgaa aaaagcaaat    660

atcacctttg agtacatgtt tgaagaagtg ccgattgtaa ttaaaaattc acatctgatc    720

aatgtcctaa tgtgggaact tgaaaagaag tcagctgttg cagataaaca tgaattgctc    780

agccttgcca gcagcaatca tttggggaag aatctacagt tgctgatgga cagagtggat    840

gaaatgagcc aagatatagt taaatacaac acatacatga ggaatactag taaacaacag    900

cagcagaaac atcagtatca gcagcgtcgc cagcaggaga atatgcagcg ccagagccga    960

ggagaacccc gctccctga                                                 979


<210>  492
<211>  1217
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (934)..(934)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (939)..(939)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (971)..(971)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (986)..(986)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1011)..(1011)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1016)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1031)..(1031)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1038)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1049)..(1049)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1063)..(1063)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1071)..(1071)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1073)..(1073)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1084)..(1084)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1102)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1109)..(1109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1113)..(1113)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1121)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1141)..(1142)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1150)..(1150)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1163)..(1163)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1168)..(1170)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1174)..(1174)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1177)..(1177)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1196)..(1196)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1201)..(1201)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1206)..(1207)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1210)..(1210)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1214)..(1215)
<223>  n is a, c, g, or t

<400>  492
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccga gatcttccag tccatcccca ttggtgccag    120

cgtggacctt gaactctgcc gaggttatcc attgcctttt gatccagatg accccaatac    180

aagtttagtg acctcggtag ccattttgga taaagaacca attattgtga atgggcaaga    240

gacctatgat tcaccagcta gccacagtag taaaacaggc aaagtcaatg gcatgaagga    300

tgccaggcca agcagcccag cggacgtggc ttcaaatagt tctcatggtt atcctaatga    360

cactgtttct ttggcttcct ccatagccac tcagccagaa ctcataactg ttcatattgt    420

caaagggcca atgggctttg gttttactat cgcagacagt cctggtgggg gtggccaaag    480

agtgaaacag attgttgaca gcccaaggtg ccgaggcctg aaagaagggg atctcatagt    540

ggaagttaat aagaagaacg tgcaggccct aactcacaac caagtggtgg atatgctggt    600

tgagtgtcct aagggaagtg aggtcacatt gttggtgcaa cgaggagggc tgccagttcc    660

caagaagagc ccaaagtcgc aaccactgga aaggaaagac agccagaata gttctcagca    720

cagtgtttcc agccaccgaa gcctgcacac agcatcccca agccacagca cacaggtgct    780

ccccgagttc ccacctgcag aggcccaagc tccagatcaa actgacagct ctggccagaa    840

aaaaccagat ccttttaaaa tctgggccca gtccaggagc atgtatgaaa aaccgacttc    900

cagattacca ggaacaggac atcttcctct gganaaaana gactggattt ggatttagga    960

ttctgggtgg naaatgaacc aggggnaacc tattttatat tggtcacatc ntaccnctgg   1020

gtgctgctga nactgacngn ccccctgang tctggaaang aantaatctg ngnggatggg   1080

aacnccagta attggaaaat cncnccacnt tgnggtccac nttatgcaaa aagctgccaa   1140

nnaaggcccn gtcaatcccc ggngcggnnn aaanggnttt tggggggccc aaaccnaaaa   1200

naaggnnccn cccnncc                                                  1217


<210>  493
<211>  814
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (130)..(130)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (224)..(224)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (450)..(450)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (454)..(454)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (795)..(795)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (801)..(801)
<223>  n is a, c, g, or t

<400>  493
taanaggaga attaactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgggacccg ggacgacgag tacgactacc    120

tattcaaagn ggtgctcatc ggggactcag gcgtgggcaa gagcaacctg ctgtcgcgct    180

tcacccgcaa cgagttcaac ctggagagca agagcaccat cggngtggag ttcgccaccc    240

gcagcatcca ggtggacggc aagaccatca aggcgcagat ctgggacacc gctggccagg    300

agcgctaccg cgccatcacc tccgcgtact accgtggtgc agtgggcgcc ctgctggtgt    360

acgacatcgc caagcacctg acctatgaga acgtggagcg ctggctgaag gagctgcggg    420

accacgcaga cagcaacatc gtcatcatgn tggngggcaa caagagtgac ctgcgccacc    480

tgcgggctgt gcccactgac gaggcccgcg ccttcgcaga aaagaacaac ttgtccttca    540

tcgagacctc agccttggat tccactaacg tagaggaagc attcaagaac atcctcacag    600

agatctaccg catcgtgtca cagaaacaga tcgcagaccg tgctgcccac gacgagtccc    660

cggggaacaa cgtggtggac atcagcgtgc cgcccaccac ggacggacag aagcccaaca    720

agctgcagtg ctgccagaac ctgtgacccc tgcgcctcca cccagcgtgg gggcacgtcc    780

tccgcccgtc cccgncacgg natcctctgg cccc                                814


<210>  494
<211>  930
<212>  DNA
<213>  Homo sapiens

<400>  494
atggatgcat taacagccaa tgggacaacc aacatacaga catctgttac aggagtgact     60

gccagcaaaa ggaaatttat tgacgacaga agagaccagc cttttgacaa gcgattgcgt    120

ttcagcgtga ggcaaacaga aagtgcctac agatacagag atattgtggt caggaagcag    180

gatggcttca cccacatctt gttatccaca aagtcctcag agaataactc actaaatcca    240

gaggtaatga gagaagtcca gagtgctctg agcacggccg ctgccgatga cagcaagctg    300

gtactgctca gcgccgttgg cagcgtcttc tgttgtggac ttgactttat ttattttata    360

cgacgtctga cagatgacag gaaaagagaa agcactaaaa tggcagaagc tatcagaaac    420

ttcgtgaata ctttcattca atttaagaag cccattattg tagcagtcaa tggcccagcc    480

attggtctag gagcatctat attgcctctt tgcgatgtgg tttgggctaa tgaaaaggct    540

tggtttcaaa caccctatac caccttcgga cagagtccag atggctgttc taccgttatg    600

tttcccaaga taatgggagg agcatctgca aacgagatgc tgctcagtgg acggaagctg    660

acagcgcagg aggcgtgtgg caagggcctg gtctcccagg tgttttggcc cgggacgttc    720

actcaggaag tgatggttcg cattaaggag cttgcctcgt gcaatccagt tgtgcttgag    780

gaatccaaag ccctcgtgcg ctgcaacatg aagatggagc tggagcaggc caacgagagg    840

gagtgtgagg tgctgaagaa aatctggggc tcggcccagg ggacggactc catgttaaag    900

tacatgcaga ggaagatcga tgagttctga                                     930


<210>  495
<211>  1205
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (887)..(887)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (904)..(904)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (943)..(943)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (965)..(965)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (974)..(974)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (989)..(989)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (994)..(994)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1004)..(1004)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1026)..(1026)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1033)..(1033)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1042)..(1042)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1053)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1055)..(1057)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1064)..(1064)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1077)..(1077)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1086)..(1086)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1090)..(1090)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1095)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1121)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1126)..(1126)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1134)..(1134)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1138)..(1138)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1148)..(1148)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1157)..(1157)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1162)..(1162)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1165)..(1165)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1168)..(1168)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1181)..(1181)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1187)..(1187)
<223>  n is a, c, g, or t

<400>  495
agagagatta ctatgagagg atcgcatcac catcaccatc acggatccta tttaggtgac     60

actatagaat cgtcgaccca cgcgtccggt tctgggaaga tggcgaaggt ctcagagctt    120

tacgatgtca cttgggaaga aatgagagat aaaatgagaa aatggagaga agaaaactca    180

agaaatagtg agcaaattgt ggaagttgga gaagaattaa ttaatgaata tgcttctaag    240

ctgggagatg atatttggat catatatgaa caggtgatga ttgcagcact agactatggt    300

cgggatgact tggcattgtt ttgtcttcaa gagctgagaa gacagttccc tggcagtcac    360

agagtcaagc gattaacagg catgagattt gaagccatgg aaagatatga tgatgctata    420

cagctatatg ataggatttt acaagaagat ccaactaaca ctgctgcaag aaagcgtaag    480

attgccattc gaaaagccca ggggaaaaat gtggaggcca ttcgggagct gaatgagtat    540

ctggaacaat ttgttggaga ccaagaagcc tggcatgaac ttgcagaact ttacatcaat    600

gaacatgact atgcaaaagc agccttttgt ttagaggaac taatgatgac taatccacac    660

aaccacttat actgtcagca gtatgctgaa gttaagtata cccaaggtgg acttgaaaac    720

ctcgaacttt caagaaagta ttttgcacag gcattgaaac tgaacaacag aaatatgaga    780

gctttgtttg gactttatat gtcggcaagt catattgctt ctaatccaaa agcaagtgca    840

aaaacgaaaa aggacaacat gaaatatgct agttgggcag ctagtcnaat aaccgagctt    900

atcngtttgc aggtcgaagt agaaggaacc caatatctct tangctgtcg aaacatgttg    960

gaaanttgca atcncccgtc taaggttcna aacncttgac ttanattccc actgcccatt   1020

gacttntggc cgnactttta cnaagcccgg ctntnnntnc acgnatttcc gttaaangcg   1080

tgtaanatgn tttnnaacca aaagcctttc gctaggggaa ngggancctg gaanattnaa   1140

cttggtgncc ccccccntcc cnacngtnta taacccgggg nacctgnaaa cccgggtttt   1200

actcc                                                               1205


<210>  496
<211>  2745
<212>  DNA
<213>  Homo sapiens

<400>  496
atggatatca aacgtaaaga aaataaaggc aatgataccc ctttggccct agagagtaca     60

aacactgaaa aggagacaag cctggaggaa acaaaaatcg gggagatcct gatccagggc    120

ttgacagaag atatggtgac tgttttaatc cgggcctgcg tgagcatgct gggagtccct    180

gtggacccag atactttgca tgccaccctt cgtctctgtc tgaggctcac ccgggaccac    240

aaatatgcca tgatgtttgc agaactgaag agtacccgca tgatcttgaa tttgacccag    300

agctcaggct tcaatgggtt tactcccctg gtcacccttc tcttaagaca catcattgag    360

gacccctgta cccttcgtca taccatggaa aaggttgttc gctcagcagc tacaagtgga    420

gctggtagca ctacctctgg tgttgtgtct ggcagcctcg gctctcggga gatcaactac    480

atccttcgtg tccttgggcc agccgcatgc cgcaatccag acatattcac agaagtggcc    540

aactgctgta tccgcatcgc ccttcctgcc cctcgaggct caggaactgc ttcagatgat    600

gaatttgaga atcttagaat taaaggccct aatgctgtac agctggtgaa gaccacccct    660

ttgaagccct cacctctgcc tgtcatccct gatactatca aggaagtgat ctatgatatg    720

ctgaatgctc tggctgcata ccatgctcca gaggaagcag ataaatctga tcctaaacct    780

ggggttatga cccaagaggt tggccagctc ctgcaagaca tgggtgatga tgtataccag    840

cagtaccggt cacttacgcg tcagagcagt gactttgata cgcagtcagg tttttccatt    900

aatagtcagg tctttgctgc agatggtgcc tccactgaga cttccgcatc tgggacctcc    960

caaggagagg cttcaactcc agaggagtct cgagatggga agaaagataa agaaggggac   1020

cgggcctctg aggaaggcaa acagaaaggc aagggcagca aacctttaat gcctacctcc   1080

actatccttc gtcttctggc agagttggtg aggtcctatg ttggtattgc taccctgatt   1140

gccaactaca gctacactgt gggccagtct gaactgatca aagaggactg cagtgtgcta   1200

gcttttgttc tggaccacct gctcccacat acccagaatg cagaagacaa ggacacccct   1260

gccttggccc gcctgttcct cgcaagcctg gctgctgcag ggagtggcac agatgcccag   1320

gtggccctag tgaatgaagt aaaagcagcc cttggacggg cactggctat ggctgagagt   1380

acagagaaac atgccaggct tcaggcagtg atgtgtatca tcagtactat catggagtcc   1440

tgcccctcca cctccagctt ctacagcagt gccacagcga agacccagca caatggcatg   1500

aacaacatca ttcggctttt cctgaagaag ggactggtta atgacctggc cagagtacct   1560

cacagcttag acctgtccag tcccaacatg gccaacacag tcaatgctgc tctgaagcct   1620

ttggaaacac tttcccggat tgtgaaccag cccagtagcc tttttggcag caagagtgct   1680

tctagcaaga acaagtctga gcaggatgcc caaggagcct ctcaagattc cagtagcaac   1740

cagcaggacc caggcgagcc tggggaagca gaagtgcagg aggaggatca tgatgtcact   1800

cagacagagg tggcagatgg ggatatcatg gatggggagg ctgaaaccga ctcagtggtg   1860

attgctgggc agcctgaggt gctcagttca caagagatgc aggttgagaa tgagctggag   1920

gacctgatag atgagttgct tgagagggat ggcggatctg ggaacagtac aattatagtg   1980

agcagaagtg gagaggatga atcacaagag gacgtgctga tggatgaagc tccttccaac   2040

ctcagccaag cttccacctt gcaggccaac cgagaagatt ccatgaatat cctggaccct   2100

gaggatgagg aggagcacac tcaggaagag gacagcagtg gcagtaacga ggatgaggat   2160

gatagtcagg atgaagagga ggaggaggag gaagatgagg aagatgatca ggaggatgat   2220

gaaggtgaag agggagatga agacgatgac gacgatggct ctgagatgga attggatgag   2280

gattatcctg atatgaacgc ttctcccttg gtccgatttg agcgctttga ccgggaggat   2340

gatctcatca ttgagtttga caacatgttc tccagtgcta cagacatccc cccatcccca   2400

ggaaatatcc ctaccaccca tccactgatg gtgcgccatg cagaccacag ttctctgaca   2460

ctgggcagtg gctcttcaac aactcgtctc acccagggca tcgggcgcag tcagaggacc   2520

ctaaggcagc tgacggccaa tactggccac accattcatg ttcactaccc tgggaatcgc   2580

cagcccaacc ctcctcttat actgcagagg ttgcttggtc cctcagctgc tgctgacatc   2640

cttcagctga gcagcagcct tcccctacaa agccggggtc gggcccgcct cctggtaggc   2700

aacgatgacg tccacatcat cgcccgttct gatgatgagc tgctg                   2745


<210>  497
<211>  853
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  n is a, c, g, or t

<400>  497
nncccatatt ccnccctaga gatactagag aggatgcatc accatcacca tcacggtcga     60

cccacgcgtc cgcttgaaaa tcttccggca tccaaggatt ccattgtgca tcaagctggc    120

atgttgaagc gaaattgttt tgcctctgtc tttgaaaaat acttccaatt ccaagaagag    180

ggcaaggaag gagagaacag ggcagttatc cattataggg atgatgagac catgtatgtt    240

gagtctaaaa aggacagagt cacagtagtc ttcagcacag tgtttaagga tgacgacgat    300

gtggtcattg gaaaggtgtt catgcaggag ttcaaagaag gacgcagagc cagccacaca    360

gccccacagg tcctctttag ccacagggaa cctcctctgg agctgaaaga cacagacgcc    420

gctgtgggtg acaacattgg ctacattacc tttgtgctgt tccctcgtca caccaatgcc    480

agtgctcgag acaacaccat caacctgatc cacacgttcc gggactacct gcactaccac    540

atcaagtgct ctaaggccta tattcacaca cgtatgcggg cgaaaacgtc tgacttcctc    600

aaggtgctga accgcgcacg cccagatgcc gagaaaaaag aaatgaaaac aatcacgggg    660

aagacgtttt catcccgcta atcttgggaa taagaggagg aagcggctgg caactgaagg    720

ctggaacact tgctactgga taatcgtagc ttttaatgtt gcgcctcttc aggttcttaa    780

gggattctcc gttttggttc cattttgtac acgtttggaa aataatctgc agaaacgagc    840

tgtgcttgca aag                                                       853


<210>  498
<211>  976
<212>  DNA
<213>  Homo sapiens

<400>  498
tgagaggtcg catcaccatc accatcacgg atcctattta ggtgacacta tagaatcgtc     60

gacccacgcg tccgcccacg cgtccgggga tgctcacgct gttgacttca gaggtaggga    120

tgctcctcca tctgacttca ggggccgggg cacttatgat ttagatttta gaggccggga    180

tggatcccat gcagatttta ggggaaggga tttatcagat ttggatttta gggccagaga    240

acagtcccgt tctgatttta ggaatagaga tgtatctgat ttggacttta gagacaaaga    300

cggaacacaa gtagacttta gaggccgagg ttcaggtact actgatctag actttaggga    360

cagggatacg ccacattcag atttcagagg tagacaccga tctaggactg atcaggattt    420

taggggcaga gagatgggat cttgtatgga atttaaagat agggagatgc cccctgtgga    480

tccaaatatt ttggattaca ttcagccctc tacacaagat agagaacatt ctgcaagaac    540

ccaagagaag tgacagaggc caagcaagaa ttaataacct accctcagcc tcagaaaaca    600

tccataccag caccattgga aaaacagccc aaccagcccc taagaccagc tgataaggaa    660

cctgaaccca ggaagaggga agaaggccaa gagtcacgct taggacatca aaagagagaa    720

gcagaaaggt atctgcctcc ttctcgaagg gaagggccaa ctttccgaag agaccgagag    780

agggagtcat ggtctggaga gacacgccag gatggagaga gcaaaactat catgctaaag    840

cgtatctatc gttccacacc acctgaggtg atagtggaag tgctggagcc ctatgtccgc    900

cttactactg ccaacgtccg tatcatcaag aacagaacag gccctatggg gcatacctat    960

ggctttattg acctcg                                                    976


<210>  499
<211>  1122
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (717)..(717)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (738)..(738)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (786)..(786)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (833)..(833)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (835)..(835)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (859)..(859)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (861)..(861)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (868)..(868)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (875)..(875)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (881)..(881)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (908)..(908)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (949)..(949)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (958)..(958)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (960)..(960)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (971)..(971)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (985)..(987)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (991)..(991)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1003)..(1003)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1009)..(1010)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1013)..(1013)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1016)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1027)..(1027)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1029)..(1029)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1041)..(1041)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1058)..(1058)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1079)..(1079)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1082)..(1082)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1085)..(1085)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1099)..(1101)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1113)..(1113)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1118)..(1118)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1121)..(1121)
<223>  n is a, c, g, or t

<400>  499
agagaaatta ctatgagagg atcgcatcac catcaccatc acggatccta tttaggtgac     60

actatagaat cgtcgaccca cgcgtccgcc gggcccgagc ggatcgcggg ctcgggctgc    120

ggggctccgg ctgcgggcgc tgggccgcga ggcgcggagc ttgggagcgg agcccaggcc    180

gtgccgcgcg gcgccatgaa gggcaaggag gagaaggagg gcggcgcacg gctgggcgct    240

ggcggcggaa gccccgagaa gagcccgagc gcgcaggagc tcaaggagca gggcaatcgt    300

ctgttcgtgg gccgaaagta cccggaggcg gcggcctgct acggccgcgc gatcacccgg    360

aacccgctgg tggccgtgta ttacaccaac cgggccttgt gctacctgaa gatgcagcag    420

cacgagcagg ccctggccga ctgccggcgc gccctggagc tggacgggca gtctgtgaag    480

gcgcacttct tcctggggca gtgccagctg gagatggaga gctatgatga ggccatcgcc    540

aatctgcagc gagcttacag cctggccaag gagcagcggc tgaacttcgg ggacgacatc    600

cccagcgctc ttcgaatcgc gaagaagaag cgctggaaca gcattgagga gcggcgcatc    660

caccaggaga gcgagctgca ctcctacctc tccaggctca ttgccgcgga gcgtganagg    720

gagctggaaa agtgccancg aaaccacgag ggtgatgagg acgacagcca cgtccgggcc    780

cagcangcct gcattgaggc caagcacgac aagtacatgg cggaacatgg acnanctttt    840

ttctcaggtg gatgaaaana ngaaaaancg agacntcccc nactacctgt gtggcaaaat    900

caactttnaa ctgatgcggg aacccgtgca tcacgcccaa ttggcattnc cttacaancn    960

caaggacatc naggaacaac ctgcnnngtg ngggttnatt ttnancccnn ganccngaaa   1020

ccccctnanc caagaaaaaa ntttatcccc aatttggnta ttaaagaagt ttatttganc   1080

cnttnttttc taaaatggnn nggggngaaa aanaattnaa nt                      1122


<210>  500
<211>  789
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (756)..(756)
<223>  n is a, c, g, or t

<400>  500
taagaggaga attaactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgccggtcg ttcggacgtc ttgcctgtcg    120

ctggaggaga ggtccgggct ctccaggaag gtggctgcgg cgacaaaatg aagatattcg    180

tgggcaacgt cgacggggcg gatacgactc cggaggagct ggcagccctc tttgcgccct    240

acggcacggt catgagctgc gccgtcatga aacagttcgc cttcgtgcac atgcgcgaga    300

acgcgggcgc gctgcgcgcc atcgaagccc tgcacggcta cgagctgcgg ccggggcgcg    360

cgctcgtggt ggagatgtcg cgcccaaggc ctcttaatac ttggaagatt ttcgtgggca    420

atgtgtcggc tgcatgcacg agccaggaac tgcgcagcct cttcgagcgc cgcggacgcg    480

tcatcgagtg tgacgtggtg aaagactacg cgtttgttca catggagaag gaagcagatg    540

ccaaagccgc aatcgcgcag ctcaacggca aagaagtgaa gggcaagcgc atcaacgtgg    600

aactctccac caagggtcag aagaaggggc ctggcctggc tgtccagtct ggggacaaga    660

ccaagaaacc aggggctggg gatacggcct tccctggaac tggtggcttc tctgccacct    720

tcgactacca gcaggctttt ggcaacagca ctgggnggct ttgatgggca agcccgtcag    780

cccacacca                                                            789


<210>  501
<211>  1284
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (936)..(936)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (938)..(938)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (952)..(952)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (989)..(989)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1005)..(1005)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1030)..(1030)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1046)..(1046)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1048)..(1048)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1053)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1055)..(1055)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1070)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1083)..(1083)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1091)..(1091)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1128)..(1129)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1151)..(1151)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1157)..(1159)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1165)..(1165)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1169)..(1170)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1172)..(1172)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1180)..(1181)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1200)..(1200)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1211)..(1212)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1217)..(1217)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1225)..(1225)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1227)..(1227)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1241)..(1241)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1257)..(1257)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1269)..(1269)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1279)..(1280)
<223>  n is a, c, g, or t

<400>  501
tagagaaatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgg cagcatggcg gcgggggcgg ctgaggcagc    120

tgtagcggcc gtggaggagg tcggctcagc cgggcagttt gaggagctgc tgcgcctcaa    180

agccaagtcc ctccttgtgg tccatttctg ggcaccatgg gctccacagt gtgcacagat    240

gaacgaagtt atggcagagt tagctaaaga actccctcaa gtttcatttg tgaagttgga    300

agctgaaggt gttcctgaag tatctgaaaa atatgaaatt agctctgttc ccacttttct    360

gtttttcaag aattctcaga aaatcgaccg attagatggt gcacatgccc cagagttgac    420

caaaaaagtt cagcgacatg catctagtgg ctccttccta cccagcgcta atgaacatct    480

taaagaagat ctcaaccttc gcttgaagaa attgactcat gctgccccct gcatgctgtt    540

tatgaaagga actcctcaag aaccacgctg tggtttcagc aagcagatgg tggaaattct    600

tcacaaacat aatattcagt ttagcagttt tgatatcttc tcagatgaag aggttcgaca    660

gggactcaaa gcctattcca gttggcctac ctatcctcag ctctatgttt ctggagagct    720

cataggagga cttgatataa ttaaggagct agaagcatct gaagaactag atacaatttg    780

tcccaaagct cccaaattag aggaaaggct caaagtgctg acaaataaaa gcttctgtga    840

tgctctttat gaaaggaaac aaacaggaag caaaatgtgg attcagcaaa caaattctgg    900

aaatactaat agtactgggg ttgaatatga aacatncnat atattggagg angaaaaaat    960

tcggcaagga ttaaagctta ctcaaaatng gccaacatac ccccnacctg tatgtgaaag   1020

gggaactggn ggaggattgg aaattngnga agnanctgaa aaaaaatggn gaattgctgc   1080

ctntactgga nagaaaaaaa taaaaaatct taaacttggg gcccactnnt ggaaaaaaat   1140

tttattactt ngggacnnnt tctgnattnn tnccccaaan nggactaaga aaaaaaaatn   1200

cccgccttcc nnaaaangtt tgggnanttc caaggccggc naaaaaaagg aggtaanttt   1260

tttcccccna aaaaaaggnn aaaa                                          1284


<210>  502
<211>  2158
<212>  DNA
<213>  Homo sapiens

<400>  502
atggcaaaat ctccggaaaa tagcaccctg gaagaaattc tgggtcagta tcagcgtagc     60

ctgcgtgaac atgcaagccg tagcattcat cagctgacct gtgcactgaa agaaggtgac    120

gttaccattg gtgaagatgc accgaatctg agctttagca ccagcgttgg taatgaagat    180

gcacgtaccg catggcctga actgcagcag agccacgcag ttaatcagct gaaagatctg    240

ctgcgtcagc aggcagataa agaaagcgaa gttagcccga gccgtcgtcg taaaatgtct    300

ccgctgcgta gcctggaaca tgaagaaacc aatatgccga ccatgcatga tctggtgcat    360

accattaatg atcagagcca gtatattcat catctggaag ccgaagtgaa attttgcaaa    420

gaagaactga gcggcatgaa aaataaaatt caggtggtgg tgctggaaaa tgaaggtctg    480

cagcagcagc tgaaaagcca gcgtcaggaa gaaaccctgc gcgaacagac cctgctggat    540

gcaagcggta atatgcataa tagctggatt accacaggcg aagatagcgg tgttggtgaa    600

accagcaaac gtccgtttag ccatgataat gccgattttg gtaaagcagc atctgccggt    660

gaacagctgg aactggaaaa actgaaactg acctacgaag aaaaatgcga aattgaagaa    720

agccagctga aatttctgcg taatgatctg gcagaatatc agcgtacctg tgaagatctg    780

aaagagcagc tgaaacacaa agaatttctg ctggcagcaa atacctgtaa tcgtgttggt    840

ggtctgtgtc tgaaatgtgc acagcatgaa gcagttctga gccagaccca taccaatgtt    900

catatgcaga ccattgaacg tctggttaaa gaacgtgatg atctgatgag cgcactggtt    960

agcgttcgta gcagcctggc agatacccag cagcgtgaag caagcgcata tgaacaggtt   1020

aaacaggttc tgcagattag cgaagaagcc aactttgaaa aaaccaaagc cctgattcag   1080

tgtgatcagc tgcgtaaaga actggaacgt caggcagaac gtctggaaaa agaactggca   1140

agccagcagg aaaaacgcgc aatcgagaaa gacatgatga aaaaagagat caccaaagaa   1200

cgcgaatata tgggcagcaa aatgctgatt ctgtctcaga atattgcaca gctggaagca   1260

caggttgaaa aagtgaccaa agagaaaatt agcgccatta accagctgga agaaatccag   1320

agccaactgg ctagccgtga aatggatgtt accaaagttt gcggtgaaat gcgctatcag   1380

ctgaacaaaa ccaacatgga aaaagatgaa gccgaaaaag aacatcgtga atttcgtgcc   1440

aaaaccaatc gcgatctgga aatcaaagac caggaaatcg aaaaactgcg cattgaactg   1500

gatgaaagca aacagcatct ggaacaggaa cagcagaaag cagcactggc acgtgaagaa   1560

tgtctgcgtc tgaccgaact gctgggtgaa agcgaacatc agctgcatct gacccgtcag   1620

gaaaaagata gcattcagca gagctttagc aaagaagcaa aagcacaggc actgcaggca   1680

cagcagcgcg aacaggaact gacccagaaa attcagcaga tggaagccca gcatgataaa   1740

accgaaaacg aacagtatct gctgctgacc agccagaata cctttctgac caaactgaaa   1800

gaagaatgtt gcaccctggc aaaaaaactg gaacaaatca gccagaaaac ccgtagcgaa   1860

attgcccagc tgagccagga aaaacgttat acctacgaca aactgggtaa actgcagcgt   1920

cgtaatgaag aactggaaga acagtgtgtt cagcatggtc gtgttcatga aaccatgaaa   1980

cagcgtctgc gtcagctgga taaacatagc caggcaaccg cacagcagct ggttcagctg   2040

ctgagcaaac agaatcaact gctgctggaa cgccagagcc tgagcgaaga agttgatcgt   2100

ctgcgtaccc agctgccgag catgccgcag agcgattgct aagcggccgc ttaattaa     2158


<210>  503
<211>  1425
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (10)..(13)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1151)..(1151)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1164)..(1164)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1166)..(1167)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1173)..(1173)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1191)..(1191)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1229)..(1229)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1236)..(1236)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1273)..(1274)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1291)..(1292)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1295)..(1295)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1304)..(1304)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1342)..(1342)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1348)..(1348)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1357)..(1357)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1371)..(1371)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1378)..(1378)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1387)..(1387)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1405)..(1405)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1419)..(1419)
<223>  n is a, c, g, or t

<400>  503
nggcgaaggn nnnggatata ctgacttacc tataaatagg cgtatcacga ggccctttcg     60

tcttccctcg agaaatcata aaaaatttat ttgctttgtg agcggataac aattataata    120

gattcaattg tgagcggata acaatttcac acagaattca ttaaagagga gaaattaact    180

atgagaggat cgcatcacca tcaccatcac ggtcgaccca cgcgtccgcc cacgcgtccg    240

ggaatggcag aggagcttac gatggacggt gttgcaggcg agcattccca aatcccaaat    300

ggctccagaa gtcatgaacc tctgtctgtg gattctgtga gcaacaacct tgcagcagac    360

gctgtaggac atggtggtgt gatacccatg catgggaatg gcctggagct ccctgtggtc    420

atggagacag accacattgc aagtcgggtc aatggcatgt ctgacagtgc cctcagtgac    480

tccattcaca ctgtggccat gagcaccaac tctgtaagcg tggcactctc tacctcacac    540

aaccttgcct ccctagaatc tgtttccctc catgaagttg gcctcagcct agaacctgtg    600

gctgtctcct ccatcaccca ggaggttgct atggggacag gtcatgtaaa tgtatcttca    660

aacagtcttt cttttgtatc accttcactg caaatggaag actccaattc aaacaaggag    720

aacatggcaa ccttgtttac aatttggggt actctgtgtg accgcgccta tccctcggac    780

tgtcccgaac atggaccaat gacctttggt cctgaccctc ccataaaaaa caaaaacagg    840

gctttccctc ccaaacagcc ttgttccccc tccagtcaat tggggggagc aaaaattggg    900

ggtttgaact ggaaaaacca tttcttgggc ggaattgctt tggacctcca attggcccac    960

aaaagtccct cctgggaaaa aacccaaatg gaacaaaaag ggaccttacc atatcctaga   1020

aaaaatacca acagggggcc ctcaaattcc ggctccttcc ccctaataaa aaagaatcga   1080

attgcctaat cttattatct caccccccca aaccaattaa aaatcaaatc tcttgctacc   1140

ctccccactg naaacatatt tttncnnact acnaaaacaa cccccctcta naatacacgt   1200

tttatttcaa aacaccaaaa aaaacctcna aaatcntaat ataaaaaaaa aattataaat   1260

aacactcata atnntatcta gaaccttacc nnacnctaaa gcanatatca actaaaaaaa   1320

aaccactcct ccttctatcc anctcccnca aaattanaaa cccataataa ncccaacnct   1380

tgcaaantat atctcaaaca tcctntcaat aataaagana tataa                   1425


<210>  504
<211>  1052
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (835)..(835)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (845)..(846)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (851)..(851)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (863)..(863)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (873)..(873)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (884)..(884)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (891)..(891)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (905)..(905)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (909)..(910)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (928)..(928)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (931)..(931)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (936)..(936)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (938)..(938)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (946)..(947)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (952)..(952)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (957)..(957)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (962)..(962)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (964)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (973)..(973)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (980)..(980)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (992)..(993)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (998)..(998)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1007)..(1007)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1009)..(1009)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1016)..(1017)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1024)..(1024)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1034)..(1035)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1038)..(1038)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1041)..(1041)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1044)..(1044)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1049)..(1049)
<223>  n is a, c, g, or t

<400>  504
aatagagaaa ttactatgag aggatcgcat caccatcacc atcacggatc ctatttaggt     60

gacactatag aatcgtcgac ccacgcgtcc gaaaaaagtg acattgacct attggaggaa    120

cataaacacg aactggatcg gatggccaag gctgataggt tcctttttga gatgagccga    180

attaatcact atcagcaaag gttgcaatcg ctgtacttca aaaagaagtt tgcagagcgt    240

gtggcagaag tgaaacctaa agtggaagca attcgttctg gctcagaaga ggtgtttagg    300

agtggtgccc tcaagcagtt gctggaggtg gttttggcat ttggaaatta tatgaataaa    360

ggtcaaagag ggaatgcata tggattcaag atatctagcc taaacaaaat tgctgacaca    420

aaatccagca tcgacaaaaa cattaccctt ttgcactatc tcatcactat tgtggaaaat    480

aagtacccca gtgttctcaa tctaaatgaa gaattgcgag atattcctca agctgcgaaa    540

gtaaacatga ctgagctgga caaagaaata agtaccttga gaagtggctt gaaagcagta    600

gagacagagc tggaatatca gaagtctcag cccccacagc ccggagataa gtttgtgtct    660

gttgtcagcc agttcatcac agtagccagc ttcagcttct ctgatgttga agaccttcta    720

gcagaagcta aagacctgtt tactaaagca gtgaagcact ttggggaaga ggctggcaaa    780

atacaaccag atgagttctt tggcattttt gatcaatttc ttcaagctgt gtcanaagcc    840

aaacnngaaa ncgaaaatat ganaaagaaa aanggaggaa aaanaacgtc nagctcccat    900

ggaanctcnn cctcaaagaa caacgtgnaa ngggancnta aaatgnnaaa anctaanaaa    960

anantgaaaa aancggaaan ttgatgacct tnntttcnct ttacccncng gaaaanngtt   1020

tganaaaacc tttnnaantt naancgaanc cc                                 1052


<210>  505
<211>  1331
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (777)..(777)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (885)..(885)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1276)..(1276)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1324)..(1324)
<223>  n is a, c, g, or t

<400>  505
gtccgagcnc caaagagata ctagagagga tgcatcacca tcaccatcac ggtcgaccca     60

cgcgtccgtt catggtgaag ctggctgaag agacagatgg gataattgtc tccaatgacc    120

agttccggga cctggcggag gagtctgaga agtggatggc aatcatcaga gaacgcctgc    180

tgccctttac ctttgtggga aacctcttca tggtacctga tgacccactg gggcgaaacg    240

gccccaccct ggatgaattt ctgaagaagc cagccaggac acaggggtct tctaaggctc    300

agcatccttc caggggcttt gcagaacatg gtaaacagca gcaggggaga gaagaggaaa    360

aaggtagtgg tggcattcgg aagacccggg aaacagagcg gctccggcgg cagctgctgg    420

aggtgttttg gggtcaggat cacaaagtgg acttcatcct gcagcgggag ccatactgcc    480

gggacatcaa ccaactgtct gaggccctgc tcagtcttaa cttttgagcc tcacctgctt    540

gagtggctgc cgccctgtca gctccagccg cctccagctc agccctttct gtgagagtcc    600

ctctgctgct cactctgatc cagaggcacc ctgagttggt gctttggatc agggaagcca    660

ctttgggaca ggtccataaa gtgaactgat cttaccgagt caggacctca gccagctctc    720

aagaggttct gctcagcctt aacttctcaa ctttgcctta gcacagggtt tctgtangga    780

gtgggggctg ctagaggggg attagttccg gagactgaga ctgttggctc cacctccaag    840

ctgagctagg gtggagggca gggtgggcag gaagtgacag gaaantaagc tggtcctctc    900

cctggctgct gctctggatg gccagagaac aagatgctcc cttgctgagc tcctggaaac    960

gtggaaggag aagctaggcc ctggcacagt ggtaagtgga ctgggccaca taggggggaa   1020

tgagccatgg aaaaaagcaa aggaaacctt gcttctggct caccattgct gttttggacc   1080

ttgttgaatt ccttggcttt actctgccta caactcggga aaaatcccgc cggcacgaca   1140

atcaaacctc gggaaccccc ttcccaaagc ggctcgccca cccccgggtg ttccctgcgg   1200

cccccggccc ttaccaaacc cctcttcaac aagcgcccct tcctccggac ccccccaaat   1260

tacccgcccc cccaancccc ccaaggggct cccttgcgcc cccaacccct ctcggcgtca   1320

cacngtctcc c                                                        1331


<210>  506
<211>  579
<212>  DNA
<213>  Homo sapiens

<400>  506
catcaccatc accatcacgg atcctattta ggtgacacta tagaatcgtc gacccacgcg     60

tccgggagcc gtgagcgctc accatcccct ctgcggggca acgtggtccc aagcccactg    120

cccactcgcc ggacgaggac cttctcggcg acggtgcggg cttcacaggg ccccgtctac    180

aaaggagtct gcaaatgctt ctgccggtcc aagggccatg gcttcattac cccagctgat    240

ggcggccccg acatcttcct gcacatctct gatgtggaag gggagtatgt cccagtggaa    300

ggcgacgagg tcacctataa aatgtgctcc atcccaccca agaatgagaa gctgcaggcc    360

gtggaggtcg tcatcactca cctggcacca ggcaccaagc atgagacctg gtctggacat    420

gtcatcagct cctaggatat ggtggaagca ccccttgtcc tgtgcttgtg ggagactttg    480

cggggaggag gcagcagaca ctggagatga cattcttcca cacgagacgg ggcttcagcc    540

gggcatggtc cctctcaagt atctcctgta ggaaggggt                           579


<210>  507
<211>  613
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (42)..(42)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (74)..(74)
<223>  n is a, c, g, or t

<400>  507
tcgagaatnt aaaaaattat ttgctttgtg agcggataca tntaatagat taattgtgag     60

cggataacaa tttncacaga attcattaaa gaggagaaat taactatgag aggatcgcat    120

caccatcacc atcacggatc ctatttaggt gacactatag aatcgtcgac ccacgcgtcc    180

ggtaacatcc tttcatgtaa ggtggtttgt gatgaaaatg gttccaaggg ctatggattt    240

gtacactttg agacgcagga agcagctgaa agagctattg aaaaaatgaa tggaatgctc    300

ctaaatgatc gcaaagtatt tgttggacga tttaagtctc gtaaagaacg agaagctgaa    360

cttggagcta gggcaaaaga attcaccaat gtttacatca agaattttgg agaagacatg    420

gatgatgagc gccttaagga tctctttggc aagtttgggc ctgccttaag tgtgaaagta    480

atgactgatg aaagtggaaa atccaaagga tttggatttg taagctttga aaggcatgaa    540

gatgcacaga aagctgtgga tgagatgaac ggaaaggagc tcaatggaaa acaaatttat    600

gttggtcgag ctc                                                       613


<210>  508
<211>  863
<212>  DNA
<213>  Homo sapiens

<400>  508
tgagaggatc gcatcaccat caccatcacg gatcctattt aggtgacact atagaatcgt     60

cgacccacgc gtccggcgcc atggcggaag cagaggagca ggaaactggg tcccttgaag    120

aatctacaga tgagtctgag gaagaagaga gcgaagagga acccaagctg aagtatgaaa    180

ggctttccaa tggggtaact gaaatacttc agaaggatgc agctagctgc atgacagtcc    240

atgacaagtt tttggcattg ggcacacatt atggcaaggt ttatttactt gatgtccagg    300

ggaacatcac tcagaagttt gatgtagtgc aggtatttgg actgtattct ggagaagaat    360

ttcacgagac ttttgactgt cccattaaaa ttattgctgt gcacccacat ttcgtgagat    420

ccagttgcaa gcagtttgtg accggaggga agaagctgct actgtttgaa cggtcttgga    480

tgaacagatg gaagtctgct gttctgcatg aaggggaagg gaacataagg agtgtgaagt    540

ggagaggcca tctgattgct tgggccaata atatgggtgt gaagattttt gacatcatct    600

caaagcaaag aatcaccaat gtgccccggg atgatataag tcttcgccca gacatgtatc    660

cctgcagcct ctgctggaag gacaatgtga cactgattat tggctggggg acttctgtca    720

aggtgtgctc agtgaaggac ggcatgccag tgaaatgagg gatttgccaa gtcgatatgt    780

tgaaatagtg tctcagtttg aaactgaatt ctacatcagt ggacttgcac ctctctgtga    840

tcagcttgtt gtactttcgt atg                                            863


<210>  509
<211>  700
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (17)..(18)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (29)..(29)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (39)..(39)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (45)..(45)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (47)..(48)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (57)..(57)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (91)..(91)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (103)..(103)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (105)..(105)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (111)..(111)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (113)..(113)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (178)..(178)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (191)..(192)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (198)..(198)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (203)..(204)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (333)..(334)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (341)..(341)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (344)..(344)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (346)..(346)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (351)..(351)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (354)..(355)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (399)..(399)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (415)..(415)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (422)..(423)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (426)..(426)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (509)..(509)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (532)..(532)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (581)..(581)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (627)..(627)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (653)..(653)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (659)..(659)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (670)..(670)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (693)..(694)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (700)..(700)
<223>  n is a, c, g, or t

<400>  509
tnacatgaga ggtcgcnnca ccaggaccnt cacggatcnt atttncnnca caaaagngaa     60

tcgtcgaccc acgcgtccgg cgccagggaa ntttttcccc cananggggg ngngagagcc    120

ggaaagatgg tggttaccag atctgcacgg gctaaggcca gcatccaagc cgcgtccncc    180

cccagttccg nnaaaaanag ggnngctgct aatgggattc aagcgcatcc agaaagtagt    240

actggatctg atgcccgaac tactgctgaa tcacagacca ctgggaagca aagtttaatc    300

cctagaactc ctaaagctag aaagaggaag agnntttttt ntgncncccc nccnnagggg    360

actgaaccat ctacggatgg agagacctct gaggaaaana aaaaatattc tgtgnggggg    420

cnncgngata ccattttaag ggtaactagg agaaggcaga tcttaattgc atgctcccca    480

gtgtccagtg ttaggaaaaa gccgaaagna actccaacaa aggagtctta cnctgaagaa    540

atagtgtctg aagcagaatc tcatgtttca ggtatttcta naattgtgct tcccacagaa    600

aaaaactaca ggagccagaa agaagtnagg ctaaatctct gacagatccc aangccaana    660

atctcatacn gaagctatat ctggatgctt gannacatcn                          700


<210>  510
<211>  1295
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (681)..(681)
<223>  n is a, c, g, or t

<400>  510
tcacccaaaa cccccctcct tagagatact atagaggatc gcatcaccat caccatcacg     60

gtcgacccac gcgtccggag gaaatgacac aaagaagatg ggagaatatg ccagtttccc    120

agtcattaca aacaaataga ggaccccagc caggaagaat aagggctgta ggaattgtag    180

gtattgaaag gaaactggaa gaaaaaagaa aagaaactga caaaaacatt tctgaggcct    240

ttgaagacct cagcaaacta atgatcaagg ctaaggaaat ggtggaatta tcaaaatcaa    300

ttgctaataa aattaaagac aaacaaggtg acatcacaga agatgagacc atcaggttta    360

aatcctactt gctgagcatg ggaatagcta acccagttac cagagaaacc tacggctcag    420

gcacacagta ccacatgcag ctggccaaac aactggctgg aatattgcag gtgcctttag    480

aggaacgagg gggaataatg tcactcacgg aggtgtactg cttagtaaac cgagctcgag    540

gaatggaatt gctctcacca gaagatttag tgaatgcgtg caagatgctg gaagcactga    600

aattacctct caggtaaagg aactctgcag gaagttgcca cctgcaccca tgatctgcat    660

ggggtagatg ggaagccaag ncaagttgcc atccctattg ccaagcaaat atttctcttg    720

aattaaataa ttcatgttaa tagggctggc atggccctac agggctagaa tcaaactctg    780

gggatttggg gaatgaataa aaagggggtt tttcccatga aatcaaaaaa ctacccccct    840

ttccctaaaa atttgggtaa acccccggaa agttccccgg gaaattattt tcctttttta    900

aggttaaaaa aaacccgggg ggggggcggg gggccccccc tggaaccccc cttttgggag    960

gggggggggg aaaaccccgg gggggcggga tccaaacccc cctccccacg ggaacacccc   1020

cccccccaaa aaaaaaaaaa cacacgtggg gggagagtcc ctaacccccc tcggggagac   1080

ggggcgcgaa attttttccc acgagggggg agagcgaaca caacacacct ctcttctcac   1140

accggagaag aaaaaaattc ttcaacaaaa acatcattca ttctcgccga tccacccact   1200

atacataaca ccacccccaa gccctcctac atccctacaa atcatacacc aaacccatcc   1260

aaccccactc tccaaaccca acaccacacc caatt                              1295


<210>  511
<211>  1202
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (906)..(906)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (958)..(958)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (976)..(976)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (997)..(997)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1010)..(1010)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1032)..(1032)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1073)..(1073)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1084)..(1084)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1094)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1099)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1102)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1113)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1120)..(1120)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1137)..(1137)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1144)..(1145)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1147)..(1147)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1152)..(1152)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1156)..(1156)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1161)..(1161)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1166)..(1167)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1183)..(1183)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1187)..(1187)
<223>  n is a, c, g, or t

<400>  511
tagaganatt actatgagag gatcgcatca ccatcaccat cacggatcct atttaggtga     60

cactatagaa tcgtcgaccc acgcgtccgc ccacgcgtcc gcccacgcgt ccgctccgcg    120

cctcgcgcta tgggacagag cccccgatcc gccagcacca cctgaggatc cagaaaccgc    180

cccagcgatg gaagaggatc aggagctgga gaggaaagca atagaagaac tgcttaagga    240

ggcaaaacgt gggaaaacta gagctgaaac aatgggaccc atgggttgga tgaagtgtcc    300

tcttgctagc accaataaaa gatttctaat taacacaatt aaaaacacat tgccctctca    360

taaagagcaa gaccatgaac aaaaagaggg cgataaggaa ccagccaaga gccaggccca    420

gaaagaagaa aacccaaaga aacacagaag ccatccttac aagcacagct tccgcgctcg    480

aggttccgcc agttactccc cgccacgaaa gcggagcagc caggacaagt acgaaaagcg    540

gtccaaccgg cggtgaggct ggaaccaggg ccagccagcc ctgcgggcct ccgtgctcct    600

tcggggtgcg gtgtgcggag aaggcctgag ctggcagggc aaacacctga gagtgacttt    660

gacattaggt cctttgttgt ttttaaagag gctgctggcc acaggcaaaa aaaaaatgac    720

ctagcaactc ttgaggaaac aagtgcaaag gaggatgtct tggcaagttt aagctacttc    780

tgcagtgtag tagacttaca tattgttgtt tatcttgttt ggaagtgtgt ttcaaaataa    840

acatgtctag aatttaaagt tttcagagat tgttaaactg gttccaattt tttggtcatt    900

tctcanaaaa ttaaaatact tataaaatcc tatattttac tttttggggg gtattacntt    960

taaaatttag aaatcntcag tccagtgacc atttttntga aaagctgtan ccctccaagg   1020

tctgggaatt tntcgaaaag cttttgatgc tctgcatttg ttttccctta ggngaaaatg   1080

tagnaatcct caangggnnt tngaatttan gnncccttcn gttcccaagg ttaaaanggg   1140

gttnntnttt cngggntttc ncaacnnttt ttttaaaaaa aancttncaa tttatttttt   1200

aa                                                                  1202


<210>  512
<211>  843
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (769)..(769)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (795)..(795)
<223>  n is a, c, g, or t

<400>  512
agagagatac tatgagaggt cgcatcacca tcaccatcac ggatcctatt taggtgacac     60

tatagaatcg tcgactctgg accttggctg tcactcagtt aagacttact tgaagattgc    120

taggctatat ctggaggatg atgatccagt ccaggcagag gcttacataa atcgagcatc    180

gttgcttcag aatgaatcaa ccaatgaaca attacagata cattataagg tatgctatgc    240

acgtgttctt gattatagaa gaaaattcat tgaagctgca caaaggtaca atgagctctc    300

ttacaagaca atagtccacg aaagtgaaag actagaggcc ttaaaacatg ctttgcactg    360

tacgatctta gcatcagcag ggcagcagcg ttctcggatg ctagctactc tttttaagga    420

tgaaaggtgc cagcaacttg ctgcctatgg gatcctagag aaaatgtatc tagataggat    480

catcagagga aatcaacttc aagaatttgc tgccatgctg atgcctcacc aaaaagcaac    540

tacagctgat ggttccagca tcttggacag agctgttatt gaacacaatt tgttgtctgc    600

aagcaaatta tataataata ttaccttcga agaacttgga gctcttttag agatccctgc    660

agctaaggcg gaaaagatag catctcaaat gataaccgaa ggacgtatga atggatttat    720

tgaccagaat gatggaatag ttcattttga aacacgagaa gccctgccna cgtgggataa    780

gcagatccaa tcacntttgt ttcaagtgaa taactttttg agaaattagt caacagcacc    840

gaa                                                                  843


<210>  513
<211>  1205
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (961)..(961)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (967)..(967)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (970)..(970)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (975)..(976)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (986)..(986)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (995)..(995)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1001)..(1001)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1053)..(1053)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1100)..(1100)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1109)..(1109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1115)..(1115)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1141)..(1141)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1152)..(1152)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1166)..(1166)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1169)..(1169)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1172)..(1172)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1176)..(1176)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1180)..(1180)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1187)..(1187)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1191)..(1191)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1196)..(1196)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1200)..(1201)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1205)..(1205)
<223>  n is a, c, g, or t

<400>  513
cantagagaa attactatga gaggatcgca tcaccatcac catcacggat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cgaccagcag cagcgtcagg aatctctaga    120

aagaagaacc tcggccacag ggcccatcct cccaccagga catccttcat ctgcagccag    180

cgcccccgtc tcatgtagtg ggcctccacc gcccccccca cccccagtcc cacctccacc    240

cactggggct accccacctc ccccaccccc actgccagcc ggaggagccc aggggtccag    300

ccacgacgag agctccatgt caggactggc cgctgccata gctggggcca agctgagaag    360

agtccaacgg ccagaagacg catctggagg ctccagtccc agtgggacct caaagtccga    420

tgccaaccgg gcaagcagcg ggggtggcgg aggaggcctc atggaggaaa tgaacaaact    480

gctggccaag aggagaaaag cagcctccca gtcagacaag ccagccgaga agaaggaaga    540

tgaaagccaa atggaagatc ctagtacctc cccctctccg gggacccgag cagccagcca    600

gccacctaac tcctcagagg ctggccggaa gccctgggag cggagcaact cggtggagaa    660

gcctgtgtcc tcgattctgt ccagaacccc gtctgtggca aagagccccg aagctaagag    720

cccccttcag tcgcagcctc actctaggat gaagcctgct gggagcgtga atgacatggc    780

cctggatgcc ttcgacttgg accggatgaa gcaggagatc ctagaggagg tggtgagaga    840

gctccacaag gtgaaggagg agatcatcga cgccatcagg caggagctga gtgggatcag    900

caccacgtaa ggggccggcc tcgctgcgct gattcgtcga gcccatccgg cgacagagga    960

nagccanaan ccagnnagcc ccaaanttcc agtgnacaaa ncacgcacag aacctgggcg   1020

cgctgctgtg aaacgtcctg acctgtgatc cantgacagt gagaaacaag tgcactctgg   1080

ttttttaaat ttgctgaaan gaanacagnc gcccnctttt tggtttaatt gctataagga   1140

nttttttggt tnaaaacccc taatcntgnt tntaangttn cggtttnccc ngggantttn   1200

ncctn                                                               1205


<210>  514
<211>  1333
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (836)..(836)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1164)..(1164)
<223>  n is a, c, g, or t

<400>  514
ggggaagcat aactgactta cctataaata ggcgtatcac gaggcccttt cgtcttccct     60

cgagaaatca taaaaaattt atttgctttg tgagcggata acaattataa tagattcaat    120

tgtgagcgga taacaatttc acacagaatt cattaaagag gagaaattaa ctatgagagg    180

atcgcatcac catcaccatc acggtcgacc cacgcgtccg cggacgcgtg ggaccgccac    240

aggcccagaa gctgccccaa agccaagcgc caagtctatc tatgagcaga ggaagcgtta    300

ctccacagtt gttatggctg atgtatccca gtacccagtc aatcacctgg tgacgttctg    360

cctgggtgag gacgatggcg tgcataccgt ggaggatgcc tccaggaagt tggccgtcat    420

ggatagccag ggccgagtct gggcacagga gatgctgctg cgagtgtctc ccgaccatgt    480

cacgctgctc gacccggcct ccaaggagga gctggagtcg tacccactgg gcgccatcgt    540

gcgctgtgac gcggtgatgc cacccggcag gagccgctcg ttgctgctgc tcgtgtgcca    600

ggaacccgag cgcgcgcagc ccgacgtgca cttcttccag ggcctgcgcc tcggggcgga    660

gctgatccga gaggacatcc agggggctct gcacaattac cgctcgggcc gcggggagcg    720

cagggcggcg gcgctcaggg ccacgcagga aggagtgcag cgcgaccgct cgcccgccgc    780

tgagaccccg cccctgcagc gccgcccgtc agtccgcgca gtgatccgca ccgtanaagc    840

ggggcgccgg gccgcggacc aaccccagcc aaagcccatt cccgaggcaa aggaagcgcc    900

aaagcctgaa accggggggg aacctctaac aaccctgatt cggcctcccc ggactgggac    960

cccgggggtc cctgactgga ggaactccca aggggaaaca gaattgtaat atctcttacc   1020

acaacgtcaa tacaatacta aaatctcctt accaaatctc catcactcaa atatatcacc   1080

tccttgcaca ccaaacaact aaaaatacgg cttatcctta tcatatcatc aaaatcatac   1140

tcttatcgcc attacctaaa cacncaacat atccgtacac tttcaccatt ctaaaagcat   1200

cacatacaac acaacctcct ttacacatat ctagtacacc ggtcttacca ttccagctcg   1260

caacactcta ctgtaatcaa tgcacaccca catccctctt caccaaatca gccatcaact   1320

gaacaccaca tac                                                      1333


<210>  515
<211>  1171
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (843)..(843)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (908)..(908)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (911)..(911)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (918)..(918)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (920)..(920)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (928)..(928)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (930)..(930)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (936)..(936)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (951)..(951)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (985)..(985)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1029)..(1029)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1037)..(1037)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1048)..(1048)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1052)..(1052)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1069)..(1070)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1074)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1077)..(1077)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1088)..(1088)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1094)..(1094)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1098)..(1098)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1105)..(1105)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1108)..(1109)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1115)..(1116)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1125)..(1125)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1128)..(1128)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1132)..(1132)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1140)..(1140)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1142)..(1142)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1148)..(1148)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1151)..(1151)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1158)..(1158)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1164)..(1164)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1166)..(1166)
<223>  n is a, c, g, or t

<400>  515
ntantagaga gattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgctgacac cggggaggca gtgtatcgct    120

cccgggaccc cgtgcgcaac ttgcgcctcc gagtccacct gcaaagaatc acatcaagca    180

actttcttca ttatcagcct gctgccgagc tcgggaagga cctcatagac ttggccactt    240

ttaggcctca gccaactgcc agtggacacc gcccagagga agacgaagag gaggagattg    300

tgattgggtg gcaggagaag ctctttagcc agtttgaagt agatctgtac caaaatgaaa    360

cagcctgtca gagtcctttg gattatcagt accgtcagga gatcctgaag ctggagaatt    420

cgggtggcaa gaaaaaccga cgaatcttta cctacactga ctctgataga tacaccaatt    480

tggaggagca ctgtcagaga atgaccactg cagccagcga ggtgccttca ttcttggtcg    540

agcgaatggc aaatgtcagg cgtcgccggc aggacaggcg agggatggag ggcggcatcc    600

tcaagtcacg catcgtcacc tgggagccct cagaagagtt tgtcaggaac aaccacgtca    660

ttaacacccc tcttcagaca atgcacatca tggcagacct ggggccctat aaaaagcttg    720

gctataagaa gtatgaacat gtcctgtgta ctctgaaggt ggatagcaat ggtgtgatca    780

cagtaaagcc tgacttcacg ggcctcaaag gaccctacag gattgagacg gagggggaga    840

aancaggagc tgtggaaata tacgatcgac aatgtttccc cccacgcaca gccggaagaa    900

gaagaacngg naacggcnan tgttcaangn atcttnatgg ccggcaaagg nagtatctca    960

acagcctcgt aggcccgact ttganatgac tgtcccaggt gccctccggc tctttgtaaa   1020

tggaaaagnt cgtttcnccc caaggctntg antatgaaaa tctctacgnn cccnttnttt   1080

gaaaaatngc caantgtncc tgggncannc ccaanntttc accanttntt angaaaaacn   1140

anacttgncc nccaaatncc tggnanggaa a                                  1171


<210>  516
<211>  866
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (745)..(745)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (798)..(798)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (803)..(803)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (817)..(818)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (866)..(866)
<223>  n is a, c, g, or t

<400>  516
agatactatg agaggtcgca tcaccatcac catcacggat cctatttagg tgacactata     60

gaatcgtcga ctctggacct tggctgtcac tcagttacag accagggcgg cgaggaggag    120

gaggactatg aaagtgagga gcagttgcag caccgcatcc tgacggcagc ccttgagttt    180

gtgcccgccc acgggtggac agcagaggcg attgcagaag gagcccagtc tctgggtctc    240

tccagtgcag cagccagcat gttcgggaag gatggcagtg agctaatact gcattttgtg    300

acccagtgca atacccggct cacacgtgtg ctagaagagg agcagaagct ggtacagttg    360

ggccaggcgg agaagaggaa gacagaccag ttcctgaggg atgcagtgga aaccagactg    420

agaatgctga tcccatacat tgagcactgg ccccgggccc tcagcatcct catgctccct    480

cacaacatcc cgtccagcct gagcctgctc accagcatgg tggatgacat gtggcattac    540

gctggggacc agtccactga ttttaactgg tacacccgcc gagccatgct ggctgccatc    600

tacaacacaa cagagctggt gatgatgcag gactcctctc cagactttga ggacacttgg    660

cgcttcctgg aaaaccgggt taatgatgca atgaacatgg gccacactgc caagcaggta    720

aagtccacag gagaggcact ggtgncagga ctcatgggtg cagcagtgac gctcaagaac    780

ttgacaggtc taaaccancg tcngtgagag gaagggnngt atagctacat gcctagagaa    840

gatgagcgga cagattgaag agcttn                                         866


<210>  517
<211>  429
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (147)..(147)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (257)..(257)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (265)..(265)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (289)..(289)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (297)..(297)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (301)..(301)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (303)..(303)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (333)..(333)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (336)..(336)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (345)..(345)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (350)..(350)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (384)..(384)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (387)..(388)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (391)..(393)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (395)..(395)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (400)..(400)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (406)..(406)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (409)..(409)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (411)..(411)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (419)..(419)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (424)..(424)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (429)..(429)
<223>  n is a, c, g, or t

<400>  517
nntagagaga ttactatgag aggatcgcat caccatcacc atcacggtat cctatttagg     60

tgacactata gaatcgtcga cccacgcgtc cgggcggccg gccggctgca tggcgcgctg    120

cgagaggctg cgcggagcgg ccctgcncga cgtgctgggc cgggcgcagg gggtcctgtt    180

cgactgtgac ggggtgctgt ggaacggcga gcgcgccgtg ccgggcgccc cggagctgct    240

ggagcggctg gcgcggnccg gcaangcgac tctgtttgtg agcaacaana gccggcncgc    300

ncngcccgag ctggccctgc acttcacgcg ccncgnattc ggggngctgn tcaccatagc    360

agctcttcaa ctccacgctg tgcnccnnga nnntnctgcn ccaganaant naccatggnc    420

tccntacgn                                                            429


<210>  518
<211>  1339
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1260)..(1260)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1279)..(1279)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1327)..(1327)
<223>  n is a, c, g, or t

<400>  518
tactgactta cctataaata ggcgtatcac gaggcccttt cgtcttcacc tcgagaaatc     60

ataaaaaatt tatttgcttt gtgagcggat aacaattata atagattcaa ttgtgagcgg    120

ataacaattt cacacagaat tcattaaaga ggagaaatta actatgagag gatcgcatca    180

ccatcaccat cacggtcgac ccacgcgtcc gcccacgcgt ccgggccggt gggagtcagg    240

gaacgagagg agccttgaca tcagcatcag tgtcaccaca gacacaggcc agaccactct    300

cgagggagag ttgggtcaga ctacacccga ggaccattcg ggaaaccaca agaacagtct    360

caagtcgcca gccatcccag agggtaagga gacgctgagc aaagtattgg aaacagaggc    420

ggtagaccag ccagatgtcg tgcagagaag ccacacggtc ccttaccctg acataactaa    480

cttcctgtca gtagactgca ggacaaggtc ctatggatct aggtatagtg agagcaattt    540

tagcgttgat gaccaagacc tttctaggac agagtttgat tcctgtgatc agtactctat    600

ggcagcagaa aaggactcgg gcaggtccga cgtgtcagac attgggtcgg acaactgttc    660

actagccgat gaagagcaga caccccggga ctgcctaggc caccggtccc tgcgaactgc    720

cgccctgtct ctaaaactgc tgaagaacca ggaggcggat cagcacagcg ccaggctgtt    780

catacagtcc ctggaaggcc tcctccctcg gctcctgtct ctctccaatg tagaggaggt    840

ggacaccgct ctgcagaact ttgcctctac tttctgctca ggcatgatgc actctcctgg    900

ctttgacggg aatagcagcc tcagcctcca gatgctgaag gacgcaaaaa gcctctacac    960

agctgcacac tgcgccccgc tcctcaacct gaagctctcc cacggtgact actaacggaa   1020

acgggcccca atccgcatgc gaactcgatt aacttaactt ggaaccctgt gaataaatcc   1080

gaaatgacct ccaaacccca ctcggaattg ttcaaaccct cggcgccccc ggggcttttt   1140

ttttggggaa acccaaccaa ccttgccaaa tttccggacc tagggaacct aatgggaaaa   1200

acactcccgg atatccccgc gaaatatccc cagccctcca aaaagcatta aggcgttcan   1260

acttccccaa gaaccaacnc accccaccag caacatcccc gtttataacc ctacaaaaaa   1320

accaganttc tacccacac                                                1339


<210>  519
<211>  1296
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (876)..(876)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (879)..(879)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (915)..(915)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (937)..(937)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (942)..(942)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (953)..(953)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (966)..(966)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1008)..(1008)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1017)..(1017)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1036)..(1036)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1040)..(1040)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1059)..(1059)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1061)..(1061)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1066)..(1066)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1078)..(1078)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1083)..(1083)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1097)..(1097)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1102)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1104)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1106)..(1106)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1111)..(1111)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1115)..(1115)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1118)..(1118)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1130)..(1130)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1143)..(1145)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1152)..(1152)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1160)..(1160)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1163)..(1163)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1165)..(1165)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1181)..(1182)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1190)..(1190)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1217)..(1217)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1221)..(1221)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1226)..(1226)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1229)..(1229)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1234)..(1234)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1240)..(1240)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1242)..(1242)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1250)..(1250)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1254)..(1254)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1258)..(1258)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1262)..(1262)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1282)..(1282)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1284)..(1284)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1292)..(1292)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1295)..(1295)
<223>  n is a, c, g, or t

<400>  519
naaatagaga aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgcccacgc gtccgcggcg gcgggagcgg    120

tcatggaggc gggcgccgga gccggcgcgg gagccgcggg ctggagctgc ccgggcccag    180

gacccacagt gaccactcta ggctcctatg aggcttccga gggctgtgag aggaagaagg    240

gccaacgctg ggggtccctg gaacgacggg ggatgcaagc tatggagggg gaggtgttac    300

tcccagctct ctatgaggag gaagaggaag aggaagagga ggaagaagag gtggaagaag    360

aagaagaaca agtgcagaaa ggtggcagtg ttggctctct gtcagtcaac aagcaccggg    420

gactgagcct cacggagaca gagctggagg agctgcgggc tcaggtgctg cagctggtgg    480

cagaactgga ggagacccgg gaactggcag ggcagcatga ggatgactcc ttggagctac    540

aggggctcct ggaggatgaa cggctagcca gcgcccagca ggcagaggtg ttcaccaagc    600

agatccagca gctccaaggt gagctgcgtt ctctacggga ggagatttcc ctgttagagc    660

atgagaaaga aagcgaactt aaggaaatag aacaggaatt gcatttggcc caggctgaga    720

tccagagtct gcggcaagca gcagaggatt ccgcaactga acatgagagt gacatagcat    780

ccctgcagga ggatctctgc cggatgcaga atgaacttga agacatggaa cgcattcggg    840

gagattatga gatggagatc gcctccctcc gtgcanaant ggaaatgaag agctctgaac    900

catccggtag tttangtctc tcaaattact ctgggtnaca anaaaaactg canganctgc    960

ggaacnctac catttcctga atgaagaata ccgggccctg caggaaanca acagcancct   1020

cccggggcaa cttgcnaatn tggaaatgaa aggaccccna nagcanccaa aaatggcntc   1080

atnccaaacc tgatttnacc tncncnaatt ncaanttnaa aattgatttn ttaaacccta   1140

tcnnnaatgc cntttttacn ccncncctcc gattctaaaa nnaatctttn ctttaaaaaa   1200

tttccaaatt ttttttnatt naaaantcnc ctcnccccgn cntaaaaaan aaancctnca   1260

anaactcatt tccaaaaagt tntnttttaa cnccna                             1296


<210>  520
<211>  817
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (716)..(716)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (740)..(740)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (758)..(758)
<223>  n is a, c, g, or t

<400>  520
nnnaatatag agaaatacta tgagaggatg catcccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg actctggacc ttggctgtca ctcagttaca gataaccacc    120

tggcccccag tgaggagtat gggctggtgg tacggctcct cactggcatt ggaaggtaca    180

acgagatgac atacatattt gatttgctgc ataaaaagca ctactttgaa gtgctaatga    240

ggaagaagtt ggatccgagt ggtaccctga aaacagccct gctggactac atcaaacgct    300

gccgtcctgg agacagtgaa aagcacaata tgattgccct gtgcttcagc atgtgccggg    360

agattggcga gaaccacgag gcagctgccc gcatccaact gaaattgatt gagtctcagc    420

cctgggagga cagcctcaag gatgggcacc agctgaaaca actgctgctg aaggccctga    480

ctctgatgtt ggatgcagca gagagttatg ccaaggactc ctgtgtgcga caggcccagc    540

actgtcagcg gctcaccaag ttgataactc tgcagattca ctttctgaac actggccaga    600

acacaatgct catcaacttg ggccgccaca agctgatgga ctgtattctg gccctacctc    660

ggttctaccg gcttctattg tggctgaagc ctacgatttt gttccagatg ggctgnaatt    720

tataccagca gtgattctan ggagacttta ttacttgnaa gatttagcag caagggttat    780

aagtcagtat atttgagaga tttcaaaata taacaca                             817


<210>  521
<211>  700
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (650)..(651)
<223>  n is a, c, g, or t

<400>  521
agagatacta tgagaggtcg catcaccatc accatcacgg atcctattta ggtgacacta     60

tagaatcgtc gactctggac cttggctgtc actcagttaa tgagatggtc cacttcgacc    120

tgccagggca ggaggaacgg gagcgcctgg tgagaatgta ttttgacaag tatgttctta    180

agccggccac agaaggaaag cagcgcctga agctggccca gtttgactac gggaggaagt    240

gctcggaggt cgctcggctg acggagggca tgtcgggccg ggagatcgct cagctggccg    300

tgtcctggca ggccacggcg tatgcctccg aggacggggt cctgaccgag gccatgatgg    360

acacccgcgt gcaagatgct gtccagcagc accagcagaa gatgtgctgg ctgaaggcgg    420

aagggcctgg gcgtggggac gagccctccc catcctgagt ccacagggag atccacagct    480

cacggagcct ggccgcggac ccctcccacc cctgccttgc cggcccctgc acatttagga    540

tatgctcctg ggtggggact gggctgtgcc cagggcctct gtcccccagg atgtcttgtg    600

gtggcggtcg gtcgttctgc cccccagggc accccctgtt gtaggctggn ntaagggaag    660

ggcaggccct cctttctgcc cctcgagaca ctcttgggag                          700


<210>  522
<211>  1209
<212>  DNA
<213>  Homo sapiens

<400>  522
atgagacggt ttaagcggaa gcatcttact gccattgact gccagcattt ggctcggagt     60

cacttggctg tgacccagcc cttcggtcaa agatggacaa acagagatcc gaaccatggt    120

ctctatccta aaccgagaac aaaaagaggg agtaggggtc agggaagtca aagatgcatc    180

cctgagttct tcctagcagg caagcagccg tgcaccaatg acatggccaa aagcaattct    240

gttggccagg acagctgtca ggactctgag ggtgacatga tctttcctgc agagagcagc    300

tgtgcactgc ctcaggaagg cagtgcaggg ccgggctcac cagggtctgc cccgccctcc    360

aggaagcggt cttggtcctc tgaggaagag agtaaccagg ctaccgggac cagccggtgg    420

gatggagttt ctaagaaagc tccacggcac catttgtctg tgccatgcac aaggcctagg    480

gaggccaggc aagaagcaga ggacagtacg tctcggctct ctgcggagtc tggtgaaacc    540

gaccaagatg ctggggacgt gggtcctgat cccattcctg actcatacta tgggcttctt    600

gggaccttgc cctgccagga agcactgagc cacatttgca gcctgcctag tgaggtcctg    660

aggcacgtgt ttgccttcct cccggtggaa gacctctatt ggaacctgag cttggtgtgc    720

cacttgtgga gggagatcat cagtgacccg ctgttcattc cttggaagaa gctgtaccat    780

cgatacctga tgaatgaaga gcaagctgtc agcaaagtgg acggcatcct gtctaactgt    840

ggcatagaaa aggagtcaga cctgtgtgtg ctgaacctca tacgatacac agccaccact    900

aagtgctctc cgagtgtgga tcccgagagg gtgctgtgga gtctgaggga ccaccccctc    960

ctccccgagg ctgaggcgtg tgtgcggcaa cacctccccg acctctacgc tgctgccggg   1020

ggtgtcaaca tctgggccct ggtggcggct gtggtgctcc tctccagcag tgtgaatgac   1080

atccagcgac tgctcttctg cctccggaga cccagctcca cggtgaccat gccagatgtc   1140

accgagaccc tgtactgcat agccgtgctt ctctacgcca tgagggagaa ggggattaac   1200

atcagcaat                                                           1209


<210>  523
<211>  2655
<212>  DNA
<213>  Homo sapiens

<400>  523
atgagccatc ctgactacag aatgaacctc cggcccctgg ggacccccag aggtgtgtct     60

gctgtggctg gtccacatga cattggtgct tcgccaggtg acaaaaagtc aaagaacagg    120

tccacacgag ggaagaaaaa gagcatattt gaaacttaca tgtccaagga ggatgtttca    180

gaaggcttga agagaggaac actcatccag ggtgtattga gaattaatcc aaagaagttt    240

catgaagcct tcattccttc cccggatggt gatcgagaca tttttattga tggggttgtt    300

gctcgtaata gagccttaaa tggggatctg gtggtcgtga aactgcttcc cgaggagcat    360

tggaaggtag ttaaaccaga gagcaatgac aaagaaacag aagctgcgta tgaatcagat    420

atccccgagg agctctgtgg acaccatctc ccgcaacagt ccctgaaaag ctataatgac    480

agtcctgatg tcattgtaga ggctcagttt gatggcagcg actcagaaga tggacatggc    540

atcacacaaa atgtgctggt tgatggtgtt aagaaactct cagtttgtgt ttctgagaaa    600

ggaagagagg atggtgatgc accggttaca aaagatgaga ccacctgcat ttcacaagac    660

acaagagctt tatcggagaa atccctgcaa agatcagcaa aggtggttta catcttggag    720

aaaaaacatt ctcgagcagc aaccggcttc ctcaaactct tggctgataa gaacagcgaa    780

ctgtttagga aatacgccct gttttctccc tcagaccacc gagtgcctag aatttatgtg    840

cctctcaagg actgtcccca ggactttgtg gcacggccta aagattatgc caacacactg    900

ttcatctgcc gcattgtgga ctggaaggag gactgcaatt ttgccctggg gcagctggct    960

aagagtcttg ggcaggctgg tgaaattgag cctgaaacag aaggaatact aacagagtat   1020

ggcgtggatt tctctgattt ctcttcagaa gttctagaat gtcttcctca aggcctgcca   1080

tggacaattc caccagagga gttcagcaag agaagggatt taagaaaaga ctgtatcttc   1140

accattgacc catcaaccgc ccgagacctc gatgatgccc tctcctgcaa gccactcgct   1200

gacggcaact tcaaagtggg agttcacatt gctgacgtga gttactttgt tccggaggga   1260

tctgatctgg ataaagtggc tgccgagagg gctacaagcg tctacttggt tcaaaaggtg   1320

gtccccatgc ttcccaggct gctgtgtgag gagctgtgca gcctcaaccc catgtccgac   1380

aagctgacct tctctgtgat ctggacactg actccagagg gcaagatcct tgatgaatgg   1440

tttggccgga ccatcatccg ctcctgcacc aaacttagct acgagcatgc acagagcatg   1500

attgaaagcc caactgagaa aatccctgcg aaagagctgc cccccatttc cccagagcat   1560

agcagcgagg aggtacacca ggccgtcttg aatctccacg gaattgccaa gcagttacgc   1620

cagcagcgct ttgtggacgg cgcacttcgt ttggatcagc taaagcttgc tttcactctg   1680

gaccacgaga ccggattgcc tcaaggatgt catatctatg agtaccgcga gagcaacaag   1740

ctcgtggagg agttcatgct cttggccaac atggcagtgg cccacaagat ccaccgcgcc   1800

ttccccgagc aggccctgct gcgccggcac cccccgcccc aaacaaggat gctcagtgac   1860

ctggtggaat tctgcgacca gatggggctg cccgtggact tcagctccgc aggagccctc   1920

aataaaagcc tgacccaaac atttggagat gacaagtact cactggcccg caaggaggtg   1980

ctcaccaaca tgtgctcccg gcccatgcag atggcactgt acttctgctc ggggctgctg   2040

caggacccag cgcagttccg gcactacgcg ctcaatgtgc ccctgtacac acacttcacc   2100

tcgcccatcc gccgctttgc cgacgtcctg gtgcaccgcc tcctggctgc cgcgttaggc   2160

tatagggagc gactagacat ggcgcccgat accctgcaga aacaggcgga ccactgtaac   2220

gaccgccgca tggcgtccaa gcgcgtgcag gagctcagta ccagtctctt ctttgctgtt   2280

ctggtcaagg agagtggccc cctggagtca gaagccatgg tgatgggcat cctgaagcaa   2340

gccttcgacg tgctggtgct gcgctacggc gtgcagaagc gcatctactg caacgcactg   2400

gccctgcggt cccaccactt ccagaaggtg ggcaagaagc cggaactcac gctggtctgg   2460

gagcctgagg acatggagca ggagccagca cagcaggtca tcaccatctt cagcctggtg   2520

gaggtggtcc tgcaggcaga gtccacagcc ctcaagtaca gcgccatcct gaagcggcca   2580

ggcacccagg gccacctggg ccctgagaag gaggaggagg agtctgacgg tgagcccgag   2640

gactcaagca ccagc                                                    2655


<210>  524
<211>  646
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (29)..(29)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (31)..(31)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (33)..(34)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (37)..(37)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (39)..(39)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (380)..(380)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (424)..(424)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (462)..(462)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (505)..(505)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (546)..(546)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (564)..(564)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (628)..(628)
<223>  n is a, c, g, or t

<400>  524
taaaaattan tttgctttgt agcggatana ntnntantng attaattgtg agcggataca     60

atttacacag aattattaag aggagaaatt actatgagag gatcgcatca ccatcaccat    120

cacggatcct atttaggtga cactatagaa tcgtcgaccc acgcgtccgg gccaggaggc    180

gggaggcggt tgccggctgc gcgccgaagc ctgcgcgcca gtcctccggc cactgctatc    240

gcccacggcc gcaccatggc cctaaaggcc gagggcgccg cactcgactg cttcgaggtg    300

acgctgaaat gcgaggaagg ggaggacgag gaggaggcca tggtggtggc cgtaattccg    360

cggcccgagc cgatgctcan agtgacccaa caggagaaga ccccaccgcc tagacccagc    420

ccgntagagg caggcagtga tggctgtgag gagccgaagc ancaggtgtc ttgggagcag    480

gagttcctgg tgggcagcag cccangaggc agcgggcggg cactgtgcat ggtgtgtggc    540

gctganatcc gggcaccctt cggncgacac agctcgctcg cacatcttgg agcagcaccc    600

tcacaccttg gacctgagcc cttctganaa gagcaatatc ctggaa                   646


<210>  525
<211>  936
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(6)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (768)..(768)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (866)..(866)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (881)..(881)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (893)..(893)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (896)..(896)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (899)..(900)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (903)..(903)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (905)..(906)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (908)..(909)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (921)..(921)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (931)..(932)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (935)..(935)
<223>  n is a, c, g, or t

<400>  525
nnnnnnggcg cggggccccc taagaatact agagaggatc gcatcaccat caccatcacg     60

gtcgacccac gcgtccggac ctggcccagg gcttctcccc tgtaatccag ggccacactg    120

atgagctctg ggggctctgc acacacccct cccagaaccg cttcctcacc tgcggccacg    180

accggcagct ctgcctgtgg gatggggaga gccatgcact ggcctggagc atcgacctca    240

aggagactgg tctctgtgct gacttccacc cgagtggggc agttgtggcc gtaggactga    300

acacggggag gtggttggtt ttggacacag agaccagaga gatcgtgtct gatgtcattg    360

atggcaatga gcagctctca gtggtccggt acagcccaga tgggttgtac ctggccattg    420

gttcccatga caacgtgatc tacatctata gtgtttccag tgatggtgcc aaatccagcc    480

gctttggccg ctgtatgggt cactccagct tcatcactca tcttgactgg tccaaggatg    540

ggaatttcat catgtccaat tctggggact atgagattct ttactgggac gtggctggag    600

gctgcaagca gctgaagaat cgctatgaga gccgagaccg ggaatgggct acctacacct    660

gtgtgctggg ctttcacgtc tacggtgagc aggggcgtgg aaacctgctg gaagggtggg    720

ggacaaggtg gagcccagtt tgggcttgga acgctgggcg tgtgtcgntg ggtgagagtc    780

caaaaacctg aagatccagc ccaggaagcc cctcgggaac gggaaagctt gcctggaacg    840

cggcagtggg tggccccggc tgccgnaaac cctgaaatgg ngaaactctg ggnccnggnn    900

ggngnngnnt aaaaagatcc ncctaacccc nnccnt                              936


<210>  526
<211>  1179
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (914)..(914)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (926)..(926)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (964)..(964)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (977)..(977)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1002)..(1002)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1006)..(1006)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1008)..(1008)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1010)..(1010)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1072)..(1072)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1074)..(1074)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1084)..(1084)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1090)..(1090)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1092)..(1092)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1099)..(1099)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1103)..(1104)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1110)..(1110)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1112)..(1112)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1119)..(1119)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1127)..(1127)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1133)..(1133)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1135)..(1136)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1146)..(1146)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1156)..(1156)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1166)..(1166)
<223>  n is a, c, g, or t

<400>  526
naaatagaga aattactatg agaggatcgc atcaccatca ccatcacgga tcctatttag     60

gtgacactat agaatcgtcg acccacgcgt ccgatttcgt gtttggccag agtggagccg    120

ggaataactg ggccaagggc cactacacag agggagccga gctggtcgac tcggtcctgg    180

atgtggtgag gaaggagtca gagagctgtg actgtctcca gggcttccag ctgacccact    240

ctctgggggg cggcacgggg tccgggatgg gcaccctgct catcagcaag atccgggaag    300

agtacccaga ccgcatcatg aacaccttca gcgtcatgcc ctcacccaag gtgtcagaca    360

cggtggtgga gccctacaac gccaccctct cggtccacca gctggtggaa aacacagatg    420

aaacctactg cattgacaac gaggccctgt atgacatctg cttccgcacc ctgaagctga    480

ccacccccac ctacggggac ctcaaccacc tggtgtcggc caccatgagc ggggtcacca    540

cctgcctgcg cttcccgggc cagctgaacg cagacctgcg caagctggcg gtgaacatgg    600

tgcccttccc tcgcctgcac ttcttcatgc ccggcttcgc gcccctgacc agccggggca    660

gccagcagta ccgggcgctc acggtgcccg agctcaccca gcagatgttc gactccaaga    720

acatgatggc cgcctgcgac ccgcgccacg gccgctacct gacggtggct gccatcttcc    780

ggggccgcat gtccatgaag gaggtggacg agcagatgct caacgtgcag aacaagaaca    840

gcagctactt cgtggagtgg atccccaaca acgtgaaaga cggccgtgtg cgacatcccg    900

cccgcggcct gaanatgtcg gccacnttca tcggcaacag cacggccatc cagganctgt    960

tcangcgcat ctccgancag ttcacggcat gttccggcgc anggcntncn tgcactggta   1020

cacggcgaag gcatggacaa aatggatttc ccgaggccga aagcaacatg ancnactggt   1080

gtcnaatacn ancattacna gannccccgn cnaaaaaang ggaattnaag aanannaggg   1140

caaganaagc ttaatncccc ccaaanggtt aggaaacga                          1179


<210>  527
<211>  1926
<212>  DNA
<213>  Homo sapiens

<400>  527
atggccaaag ccgcggcgat cggcatcgac ctgggcacca cctactcctg cgtgggggtg     60

ttccaacacg gcaaggtgga gatcatcgcc aacgaccagg gcaaccgcac cacccccagc    120

tacgtggcct tcacggacac cgagcggctc atcggggatg cggccaagaa ccaggtggcg    180

ctgaacccgc agaacaccgt gtttgacgcg aagcggctga tcggccgcaa gttcggcgac    240

ccggtggtgc agtcggacat gaagcactgg cctttccagg tgatcaacga cggagacaag    300

cccaaggtgc aggtgagcta caagggggag accaaggcat tctaccccga ggagatctcg    360

tccatggtgc tgaccaagat gaaggagatc gccgaggcgt acctgggcta cccggtgacc    420

aacgcggtga tcaccgtgcc ggcctacttc aacgactcgc agcgccaggc caccaaggat    480

gcgggtgtga tcgcggggct caacgtgctg cggatcatca acgagcccac ggccgccgcc    540

atcgcctacg gcctggacag aacgggcaag ggggagcgca acgtgctcat ctttgacctg    600

ggcgggggca ccttcgacgt gtccatcctg acgatcgacg acggcatctt cgaggtgaag    660

gccacggccg gggacaccca cctgggtggg gaggactttg acaacaggct ggtgaaccac    720

ttcgtggagg agttcaagag aaaacacaag aaggacatca gccagaacaa gcgagccgtg    780

aggcggctgc gcaccgcctg cgagagggcc aagaggaccc tgtcgtccag cacccaggcc    840

agcctggaga tcgactccct gtttgagggc atcgacttct acacgtccat caccagggcg    900

aggttcgagg agctgtgctc cgacctgttc cgaagcaccc tggagcccgt ggagaaggct    960

ctgcgcgacg ccaagctgga caaggcccag attcacgacc tggtcctggt cgggggctcc   1020

acccgcatcc ccaaggtgca gaagctgctg caagacttct tcaacgggcg cgacctgaac   1080

aagagcatca accccgacga ggctgtggcc tacggggcgg cggtgcaggc ggccatcctg   1140

atgggggaca agtccgagaa cgtgcaggac ctgctgctgc tggacgtggc tcccctgtcg   1200

ctggggctgg agacggccgg aggcgtgatg actgccctga tcaagcgcaa ctccaccatc   1260

cccaccaagc agacgcagat cttcaccacc tactccgaca accaacccgg ggtgctgatc   1320

caggtgtacg agggcgagag ggccatgacg aaagacaaca atctgttggg gcgcttcgag   1380

ctgagcggca tccctccggc ccccaggggc gtgccccaga tcgaggtgac cttcgacatc   1440

gatgccaacg gcatcctgaa cgtcacggcc acggacaaga gcaccggcaa ggccaacaag   1500

atcaccatca ccaacgacaa gggccgcctg agcaaggagg agatcgagcg catggtgcag   1560

gaggcggaga agtacaaagc ggaggacgag gtgcagcgcg agagggtgtc agccaagaac   1620

gccctggagt cctacgcctt caacatgaag agcgccgtgg aggatgaggg gctcaagggc   1680

aagatcagcg aggcggacaa gaagaaggtt ctggacaagt gtcaagaggt catctcgtgg   1740

ctggacgcca acaccttggc cgagaaggac gagtttgagc acaagaggaa ggagctggag   1800

caggtgtgta accccatcat cagcggactg taccagggtg ccggtggtcc cgggcctggg   1860

ggcttcgggg ctcagggtcc caagggaggg tctgggtcag gccctaccat tgaggaggtg   1920

gattag                                                              1926


<210>  528
<211>  1311
<212>  DNA
<213>  Homo sapiens

<400>  528
atgaggctgg cgcggctgct tcgcggagcc gccttggccg gcccgggccc ggggctgcgc     60

gccgccggct tcagccgcag cttcagctcg gactcgggct ccagcccggc gtccgagcgc    120

ggcgttccgg gccaggtgga cttctacgcg cgcttctcgc cgtccccgct ctccatgaag    180

cagttcctgg acttcggatc agtgaatgct tgtgaaaaga cctcatttat gtttctgcgg    240

caagagttgc ctgtcagact ggcaaatata atgaaagaaa taagtctcct tccagataat    300

cttctcagga caccatccgt tcaattggta caaagctggt atatccagag tcttcaggag    360

cttcttgatt ttaaggacaa aagtgctgag gatgctaaag ctatttatga ctttacagat    420

actgtgatac ggatcagaaa ccgacacaat gatgtcattc ccacaatggc ccagggtgtg    480

attgaataca aggagagctt tggggtggat cctgtcacca gccagaatgt tcagtacttt    540

ttggatcgat tctacatgag tcgcatttca attagaatgt tactcaatca gcactcttta    600

ttgtttggtg gaaaaggcaa aggaagtcca tctcatcgaa aacacattgg aagcataaat    660

ccaaactgca atgtacttga agttattaaa gatggctatg aaaatgctag gcgtctgtgt    720

gatttgtatt atattaactc tcccgaacta gaacttgaag aactaaatgc aaaatcacca    780

ggacagccaa tacaagtggt ttatgtacca tcccatctct atcacatggt gtttgaactt    840

ttcaagaatg caatgagagc cactatggaa caccatgcca acagaggtgt ttacccccct    900

attcaagttc atgtcacgct gggtaatgag gatttgactg tgaagatgag tgaccgagga    960

ggtggcgttc ctttgaggaa aattgacaga cttttcaact acatgtattc aactgcacca   1020

agacctcgtg ttgagacctc ccgcgcagtg cctctggctg gttttggtta tggattgccc   1080

atatcacgtc tttacgcaca atacttccaa ggagacctga agctgtattc cctagagggt   1140

tacgggacag atgcagttat ctacattaag gctctgtcaa cagactcaat agaaagactc   1200

ccagtgtata acaaagctgc ctggaagcat tacaacacca accacgaggc tgatgactgg   1260

tgcgtcccca gcagagaacc caaagacatg acgacgttcc gcagtgccta g            1311


<210>  529
<211>  1271
<212>  DNA
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(3)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (501)..(501)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (580)..(580)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (607)..(607)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (620)..(620)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (628)..(629)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (639)..(639)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (648)..(648)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (662)..(662)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (769)..(769)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (771)..(771)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (830)..(830)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (832)..(833)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (846)..(846)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (857)..(857)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (860)..(860)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (871)..(871)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (876)..(877)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (884)..(884)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (892)..(892)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (896)..(896)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (903)..(904)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (906)..(906)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (931)..(932)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (944)..(945)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (951)..(951)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (956)..(956)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (991)..(991)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (999)..(999)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1003)..(1003)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1012)..(1012)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1043)..(1043)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1076)..(1076)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1102)..(1102)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1171)..(1172)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1203)..(1204)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1207)..(1207)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (1264)..(1264)
<223>  n is a, c, g, or t

<400>  529
nnnaagatat actgacttac ctataaatag gcgtatcacg aggccctttc gtcttcacct     60

cgagaaatca taaaaaattt atttgctttg tgagcggata acaattataa tagattcaat    120

tgtgagcgga taacaatttc acacagaatt cattaaagag gagaaattaa ctatgagagg    180

atcgcatcac catcaccatc acggtcgacc cacgcgtccg cggccgtccc cgggctccac    240

cgcgcccgca gcccacggtg tcacctcggc cccggagagc aggccggccc cgggctccac    300

cgccccccca gcccacggtg tcacctcggc cccggacacc aggccggccc cgggctccac    360

cgccccccca gcccacggtg tcacctcggc cccggacacc aggccggccc cgggctccac    420

cgccccccca gcccacgggg tcacctcggc cccggacacc aggccggccc cgggctccac    480

cgccccccca acccacgggg ncaccacagc cccggacgac aagccggccc cgggcaccac    540

cgcccccaca gcccaaaggg acacacggcc cccgacaacn agccaggcgc agaaaccacc    600

agcaccncaa cccaaaaagn aaccacgnnc acacgaccna gcacaaanga agcacaacaa    660

anaacgggcc acaaaaaaaa acgaaccacg gaagaaccac aacggaaaac cccaaggccc    720

ggaacaaagg aaaaaacaaa aaacagaaag gaccacaccc gaaacacana nagaccgaaa    780

aaaaaaaaca aagccacacc ccaaaaagac ccccaaaaaa caccacaccn cnnaacaaca    840

aacaanccca cacgacnaan caacccaaaa naaaannaaa cacnaacaga anaacnaaac    900

ccnnanaccc caaaaaaaaa acccaacaca nncaaaaaaa aaannaaaaa nccaancaac    960

ccccaaaacc cgacacaaag acaacaaaac naacacccnc ccnagacagc cnaaaaaaaa   1020

ccagcacaaa caacaaccca ccncccacca acagaaaaaa aacgcacgaa acccanaaac   1080

aacaagacac aacacacaaa cnaacaaaac aaaaccgccc accccgaaaa accccacaaa   1140

gcaacacacc caccccagcg aaagcaaaac nnaagaccca accagaaaac acccaaacaa   1200

cannganaca cccgcacgac agaacacgaa acacacaaaa cccaccaaaa gccaacacaa   1260

caancacaac a                                                        1271


<210>  530
<211>  10831
<212>  DNA
<213>  Human

<400>  530
agtttgcggc actgttgtca tttccggggt aagatggctg cagtccgtat gctgagaacc     60

tggagcagga atgcggggaa gctgatttgt gttcgctatt ttcaaacatg tggtaatgtt    120

catgttttga agccaaatta tgtgtgtttc tttggttatc cttcattcaa gtatagtcat    180

ccacatcact tcctgaaaac aactgctgct ctccgtggac aggttgttca gttcaagctc    240

tcagacattg gagaagggat tagagaagta actgttaaag aatggtatgt aaaagaagga    300

gatacagtgt ctcagtttga tagcatctgt gaagttcaaa gtgataaagc ttctgttacc    360

atcactagtc gttatgatgg agtcattaaa aaactctatt ataatctaga cgatattgcc    420

tatgtgggga agccattagt agacatagaa acggaagctt taaaagattc agaagaagat    480

gttgttgaaa ctcctgcagt gtctcatgat gaacatacac accaagagat aaagggccga    540

aaaacactgg caactcctgc agttcgccgt ctggcaatgg aaaacaatat taagctgagt    600

gaagttgttg gctcaggaaa agatggcaga atacttaaag aagatatcct caactatttg    660

gaaaagcaga caggagctat attgcctcct tcacccaaag ttgaaattat gccacctcca    720

ccaaagccaa aagacatgac tgttcctata ctagtatcaa aacctccggt attcacaggc    780

aaagacaaaa cagaacccat aaaaggcttt caaaaagcaa tggtcaagac tatgtctgca    840

gccctgaaga tacctcattt tggttattgt gatgagattg accttactga actggttaag    900

ctccgagaag aattaaaacc cattgcattt gctcgtggaa ttaaactctc ctttatgcct    960

ttcttcttaa aggctgcttc cttgggatta ctacagtttc ctatccttaa cgcttctgtg   1020

gatgaaaact gccagaatat aacatataag gcttctcata acattgggat agcaatggat   1080

actgagcagg gtttgattgt ccctaatgtg aaaaatgttc agatctgctc tatatttgac   1140

atcgccactg aactgaaccg cctccagaaa ttgggctctg tgagtcagct cagcaccact   1200

gatcttacag gaggaacatt tactctttcc aacattggat caattggtgg tacctttgcc   1260

aaaccagtga taatgccacc tgaagtagcc attggggccc ttggatcaat taaggccatt   1320

ccccgattta accagaaagg agaagtatat aaggcacaga taatgaatgt gagctggtca   1380

gctgatcaca gagttattga tggtgctaca atgtcacgct tctccaattt gtggaaatcc   1440

tatttagaaa acccagcttt tatgctacta gatctgaaat gaagactgat aagacattct   1500

tgaacttttt gagcttccaa agagtatgta aaccctagct gtgccagcac atgttcatct   1560

ttacaattta tattgtaaat gatttgtatc gtatgattaa ggatctaagg cacaatattt   1620

gtcactgttc tattagactt tttactgaaa atgaataatg gtgtaatggt tctcctgggg   1680

ctgtcacatt ttataggtca gagtgtgact tcttaatatg gtgctgatgt ttttgtgtca   1740

atggcttgaa actggcaaga ttaacaaaat taggccgggc atggtggctc acgcctgtaa   1800

tcccagcact ttgggaggcc caggtgggcg gatcacctga ggttagaagt ttgagaccag   1860

cctggccaac atggtgaaac ctggcctcta ctaaaaatac aaaaattagc cgggtgtggt   1920

ggtgggtacc tataatccca gctacttggg aggctgaggc aggagaatcg cttgaacctg   1980

ggaggtggag gttgcagtga gctgagatcg tgctattgca ctccagcctg ggcgacagag   2040

caagacgcca tctcaaaaac aaaaaaacaa aattcatgtt actaaaagac aggtagccat   2100

atacagacag tatatgccct atttttttta actgactctt aatgaaactt taattttact   2160

taattaagaa atggaattta tatacaaaaa tattttccat ttccgttatt atgctaattg   2220

ttgtatgaaa taagtgcaat tatacttctc ttttgagata tccaagagta tattcttgct   2280

ctgtatagag aatatcatct gatagtgtct tatttatatt aattaatgtc tttgaaaagg   2340

gaaaagtata aactggcctt aaaattgtcc aattatagtt ttataaccag tctattaaag   2400

gtgtttgttt aaaatggata tagttttaga tttgtggtaa tgctttggta ttttcttggg   2460

gaagaccttc acctttgcaa acttccctca tgtaaggaag gtactttaaa tgtagcagcc   2520

actgacattt ctttttttaa aaaaaatttg agaagtctac ttccttttaa cttttttggt   2580

cttcagctaa aaaataggat aagaaattaa ggtctattcc attctccata tcctgggtaa   2640

gaatgtaaat aagaggagaa ggaagagtct aatagtaatt atggatataa aaaataagaa   2700

attttgtata gaaatgaagg tttcataatg atcattttgt taaaggtcta ctttaatcag   2760

aaatagcaac gagatgaatg tatccaacat ttcaatttgc attcggaaat ccatgttgtt   2820

tctaatattg tccagttgaa aactgtatgc caaaattagt tgtttaagtg aagttttgtg   2880

acagaaaaaa ggttgtttta atatctactt ggtttttctc aaaatggaaa taattttaaa   2940

atcaggaaag aataaatcag ccaggtgtga tgacttgtaa ctgtaatccc agttataggg   3000

gaggctgaag caggaggatc acttgaggcc aggagtttga gaccagcctg ggcaacatag   3060

tgagatccca tctcaaaaaa cattattttt aaaattagcc tggtggctca cgcctgtaat   3120

cccagcactt tgggaggccg aggtggccag atcacctgag gtcaggagtt cgagaccacc   3180

ctggccaaca tggtgaaacc ccatctctac agttttgtaa aaatacaaaa aattacctgg   3240

gcctggtggc acacgcctgt agtcccagct acttgggagg ctgaggcagg agaattgctt   3300

gagcccaaga ggtggaggtt acagtgagca gagatcacac cactgcactc cagcctgggt   3360

ggcagagcaa cactttgtct cagaaaaaaa aaaaaaaacc aaaaagccaa gtgtggtggt   3420

gtgcacctat agtcccagct actcaggaag ctgagacaag aggatcaatt gagcccagga   3480

gttcaaagct gtagtgagct gtcattgtgc cactatcctc cagtatgggt gacagagtga   3540

gacctggtct ctaaaaaata aaataaaata aaaaaaacag gtcaaataaa tgctgttgtt   3600

gtaaaatttc agataataca aagagttaac caataaaaga aaaagtcatt cataatctta   3660

ccactattaa cattttgatg tatctatctg tatgtatggc tattcttttt tgttaaaaca   3720

tgatcatagc atatctacta ttttattatt tgatttttaa aatttaacat tatattatgg   3780

gtaaccttac atgtcaataa acaattccac attgtcatgc tttaaatggc tgcataggct   3840

gggtgtggtg gctcacgcct gtaatcctac cactttggga ggccaaggca ggtagatcac   3900

aaggtcagga gttcgagacc agcctggcca atatggtgaa acctcatctc tattgaaaat   3960

acaaaaatca gccaggcacg gtggcaggcg cctgtagtcc acctactcgg gaggctgagg   4020

caggagaact gcttgaaccc agcggcagag gttgcagtga gccaagattg agccactgca   4080

ctccagcctg gtgatagagc gagactctgt ctctaaataa ataaataaat aaataaatgt   4140

ctgcatagta ttccattgta tgcatttatt atacattcaa acattaaaca tctaccatac   4200

caatcatggt tctaagcata cagtagccac cttcatgctt ccttgattgg gcttacagtc   4260

tagtaaggag acagatatta aataactgca taaaacactg ttcttggtag gtaataaccc   4320

agatgctatg agccatccag taaaggttac cgatcttatc tggaaggatc agaagatgga   4380

tgtcccataa tttaaccaat tatctattga taggcattta ttgagtttta aatgaataat   4440

gacatgatca ataaaaatgt cctcctcact taaagaatag aaaaaccagg agaagggagt   4500

tctgaaataa gtaagtatgt aggtccagca tcaatggctc aagatactct attcccaaat   4560

aacccttaag ttatctggtt ctattccaac ccttgggtat tactatcttc tctttggtct   4620

catgcattga gaattcagca aaggatttgt tccctacagt gtgcacggcc cttaggatag   4680

caggattccc tgaagagggc caaaggggca ggagcgcagc cttagtggca gtgctggtcc   4740

atgaggctct acaaagcaag ggatgggtgt ttgggaggag gaaaaggctc ttgctgtact   4800

cctagaggtt ggaattaaag tggaaaagcc agaaaattca agtcctttac taacatgtct   4860

ggagattaga aggtatatgt acatggggga gaagccaaaa ttattgctgc gagtggtcag   4920

caagaaaatc aaggctcttt tcattatttt gagcattcct ctgatatttg aaaaggaagt   4980

acaacaggaa aggaagtctg aggatggaag ctaaaattgg tatgaattta tattttagag   5040

atcaaaatgt accttatgtt gaaacctatg taagaagtga ttatgtagaa agagtgaaag   5100

tgatagctct tagtctggaa agcccactgg cttgtttggg catttctcat ggcttcccac   5160

tcaaagtgga tccccaaaat cacttgatgg atttccttgc tgatttctaa gtaaactatg   5220

gtttaagaaa gaaatgacag ggctcagcac tgccctacag taccaagaat acaaatgttt   5280

ccatgaagtc ttcaaaggca tttgtaaaat tcaggctgta agtgattagt tagttcattc   5340

tgcacttatt tattaactgt atattcagtt ccaggctcta gggtagagat tatggataaa   5400

ggtgaattag atagatgaag tttttgccct cacagcaaaa gctttagcca ataattaaag   5460

ctatcactgg aagtgggtct gtgccaataa cctagagaag agcagtgctt ttagagttga   5520

gctatattcc caatcagttc ttaatggtgg ttttaccccc ttccctctac actgtctttt   5580

cttgagattg gatcatgtgt gtgaacccac atcatttcca gtcaaaatca ccaagagagg   5640

ccggacacag tggctcatgc ctataatccc agcactttgg gaggcctaaa tgggtgggcc   5700

tcttgagtcc agagtttgag accagcctgg gcgaccccag ctctaccaaa aaaaccaaaa   5760

aacaaaaaat accaaaaaaa aaaaaaatta ggccgatgaa gtgacatgca cctgtgtgcc   5820

acctactcag gaggctgagg tggcaggatc acttgcatct gggggcaaag gctgccgtga   5880

gctgagattg tgccattgcg ctccagcctg ggcgacagag caagactctg tgtgtgtgtg   5940

tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtata cacacacaca   6000

tatatataca cacaccccca ggagaccttt tgtctttctt ggttcatgtg cccatcagtg   6060

tgggcaggag aatagaatac tctgtccaca cttgagtctt agtcaccttt ggagcctagg   6120

agtcagccat cctcattcaa ctacatggat cgagaatggg aatctgggag aattttttta   6180

tgggcagatt aaaaaggaag ttaactatgt aaagtaaggc attgccttcc caccccatcc   6240

cacctcagtt cgtgttaaat tatgaatttt tctaagagag ttctttaatg acatggatag   6300

agaggaagct gaggtggcag tagagtaggg agtggaaggc aaatacataa gatactatta   6360

aactgtgaag ctgtttgtta caattccaag attttataat ttctccaaca aaaaacattt   6420

gtattttctt cccagtttaa gttcaatgtt aatttgagaa ataattctac tctcaaactt   6480

catgttatgc tgacagttca actgatgctg tcaaaatgtg aattactaac ttcagtattc   6540

tctattcatc tgatttttct taaaatgttt gcgtgttaat atactcacta gctttaatgc   6600

tctactctta tactggcacc ttaattatgg taaaaggtaa aaggttaagt taaaattccc   6660

aatcctagtt atttggtcaa acagaagatt aacagaactc catggcttac cacaggaata   6720

tttatcaaga gaaaaagaag atacctattt gaatttacat gacactttct gtgaaatatc   6780

tggattacca gattagtctg aaacaaatgc cttccaaatt ctacagcgca tgcccaaggc   6840

actctttaca gtacctgttc gggtcttttc ttctaatttt aagcacctac ccaaacgtct   6900

tcccaggctt gtcataataa gcaaataacc tcagagcaga caaagtgatt caatctaaga   6960

accttgaatt tctctccttt tcacctcaaa atttctattc tcacactttc tttttgtttc   7020

tctttccgag aagtggttct ccatcagcaa ataccaactg ttttctgtcc tctattattt   7080

attccatctc ttcctcctga tccctgcccc atgttgaacc cccattgccc cactttgatc   7140

cttcagtctc ttcctcacat ccagaactgt accagattta ctcccttagc acactgatta   7200

aaatttattt ccatttcctt atggaggagg tattagagac tgatcccaga cctctacaaa   7260

tttcattgtg gcagggtaat gttatgtgtc cataaacctt gttccttttc tttcagcctg   7320

cagttaggta gagccatgtc atttatttgt aactattaga atatgggtat atgggttgaa   7380

gtaatgtagg ccatttccag acatggccca taacacttct caagagattc ttcatattct   7440

atctcttccc ctccaacatg cacccttcaa ggttgaagat ggcaccacac aagatagaag   7500

gagccagtgt tccaaatgac taggcagagc agaatgctcc cctccctaca ccctagcacc   7560

aattggtttg gatgtgatag ttgaataata cacttttatt gttttaagac attaatattt   7620

tgagattaat ctgcaagtct agttagtaaa actcgaactc tgagctgtct aatgcagtag   7680

cctctagcca catgtagcta tttaaattta aattttaatt ttaattaatc aaaattcaac   7740

tcagatatac tagccacatt tcaattgctc agtagccaca ctaattaaat ttaaatttaa   7800

atagctacat gtggcttata gcaccatacc agatagcaca gatgtagact gtttccatca   7860

tcacagaaaa ttctattgga tagtgctgcc ttaactaata agacacaaat gttcttattt   7920

tttaaatagt ccctaaaaca aacgaaaaac aaagaactcc cttctctaat ggcaaatttc   7980

agtttgccta aaagaagact cagaatgctt ttcttatatt gttacctctg actgccacta   8040

aatgaataaa tttcctgtct tgctccttct gccaaacttc ttgaatgggt gatctttaac   8100

tccttgcaat cctggctttt ttccccagtg ctcacctgta atcagtgttg gccacaactc   8160

ccacccagat gtctcctaaa tagttctctg aacccacctc tgtcctgatc tacagacatt   8220

cattccaatg ctttagcatt tcaaggtcat caaatgactc agtgacatct cagacagtca   8280

gacagaccag gtcaactatg aactatttat gccaaacctt acatggttca tgttatcctt   8340

gctatcccat caaaataacc acaggctttt tttttttttt tttttaattt ttgagatgga   8400

gtctcactct gtcaccccga ctagagtgca gtggtgcgat ctcggctctg ctcactgcaa   8460

cctccgtctc ctgggttcaa acagtgctca ttcctcaact cccaagtagc tgagattaca   8520

ggcatgcacc atcacgcctg gctaattttt ctatttttag cagagatggg gtttcgccat   8580

gttggccagg ctggtctcga actcctgacc tcaagtgatc tgcccgcctc cacctcacaa   8640

agctttggga ttacaggcat gagccacggt gcctggcctg cagcctcctt tattttacaa   8700

aaggcattac cacttaaaca ctgaagatag cacgaatctc tgatgtttgc aagttcagaa   8760

taaaatggaa atgaaaattc attatgtggc agtctcagta ctgagcacaa aggcttttaa   8820

ccacaagcaa attactgtgc tagccagacc gtgtgagaga actccaggcc agcttgctaa   8880

aactgagcag gagaatttgg agagagtcca gaggagagcc acagaaacaa ctgaagcatg   8940

acaagaataa ttgcagttct gttatagaga ggtcatctat atcaggcttt tatggagtac   9000

catgtggaat gttaccacgc agagcatggg gaacagctgt tgtgactcaa caagagacag   9060

gacagaagaa atgagaacag gtggaagatc aataatttag gtttgatatg gggaaagatg   9120

gaacagtcaa agggattcac actgattttt ggctgagcag aaggcagagt ctcctccaac   9180

gggcaatgta agtgccccca ctcatctaca ccccgagaag agccatcaaa ctgtattaaa   9240

cttggaaaaa gctatttaac ttcaagtgtg ctgcgagaaa acttcataat agttcctaag   9300

atgtgctaaa aagtaaagtc caaaaagatc ataaagtctg tagagaagtt ctaagagtgc   9360

agtcagctat aaaaacctag caatttaatt tcttagaaaa atgtagctgg agttcaaact   9420

gtagtaacaa aggcaagtaa attaagttgt gggcaggtgt aattaagtta ataggaatgg   9480

cagggatgaa tataaatcag aacaggacta acagtttgaa acattagata ttcaaatgct   9540

cagagctgat gagccgagcc actacgctaa caactctgca aaccaaaggt ttcacaaatt   9600

gcacaagaac ctggcctcga tcccattgtg ttgctggcat aagattagaa gggcctgttg   9660

gttcaattgt tgctttggac agaggaggac aaacttgcca cagtgaagaa atcattttta   9720

aaaaccacca ctgtccttta gtgcactaat ttctctaata actaggtgta tattagaaat   9780

aatgatatat aagtgcagta tactccagtt tcaacagaat ggtgtcactt ctgtaaaatg   9840

ttgattttca gattgtcata ctttctaaat acaaaaattt gtcacagctt ccacatttac   9900

aagatattaa acattccata aaatatttgt agaaatatga aaaaccaatt tttgtagttg   9960

ccttttgaaa tgtatacaaa atatcccaca tgggcaacat ggtaaaacct cgtctctaca  10020

aaaaaaaaaa aaaaaataca aaaagttagc caggcctggt ggtgcacgcc tgtggtccca  10080

gctactcggg aagctgaagt gagatcacct gtgcccagga ggtcgaagct gcagtgagct  10140

gtgattgcac cactgcactc cagcctgggt gacagagtga gactttgtct caaataaaca  10200

aaaagagaca tatacaaaat atattagaaa gttgggttaa tatcctacaa acaaagtatt  10260

acatagtttg cacaggatta tgtgtgtaaa aagttttaaa ttcagtatag cttttatttc  10320

tgcagaacta aaagtagtgc ataaaaataa aagtgggatg agcatatctt tttaatttgc  10380

tatgcagtaa aaagtatctc agtcaacata taggaaacca gtgccatttc tgtatcattt  10440

gacaccgaag gggtattgtt ttttgttttg ttttgttttt cttttgaaga aagactttta  10500

tgtcttttat tctattcttc cgatttgggg tttaaattac ccccaataag tttgcagaat  10560

attctgatta ctactgctta ggtgatatat ttcatatgag aactatcttt acacaatggg  10620

aaaaaatatg gtaaccactt cattcatcag agaagttgtg ttttgtttac ttgtattttg  10680

tttgctaaat gaaattggtt atttagactc atggcatgct ttttctcaaa tggagattta  10740

aaagtcattt ccaatgtcct tctaacttct ggccaattcc cagtaggcta tagaataaac  10800

agttttcata taataaaaaa aaaaaaaaaa a                                 10831


<210>  531
<211>  4352
<212>  DNA
<213>  Human

<400>  531
acaaacctga aacgaaatct ttgcaaccag tacagcctgc gcggggcgcg gcccagtcca     60

tcccccttcg gatgcgcaga agcagaggtc accacgccgg acccctcgat tccctcgcgg    120

gcgattcctg gctccttcac caccccagca ctccaagacc cccgcccttt ggcctgaggc    180

tcccactgcc ctagccagtt cccgggctca cttccagctt ttccagaaag cttggccacg    240

cccctcggcc cagactctca ggccactcgg ccgcaattaa cccgcgtctc tgcgcctttt    300

taggcccctc cccctcggtc gtgcccttgt catctcttag gccccgtctc accctttcgg    360

atgcctcccc tagaacccta ccactttcca cccctttccg tctgttattt ctcccaaact    420

tgcgcccgca caggcccctc tggaacactc ctgccccgta gtgcccctcg tccccgctcc    480

gtagagaaag agcgtgcgtg ccgcgcattt ctggcctggg gagcgggtgg agtaaacctg    540

cgggaaccat tttacgacaa cgtgcggctg tgcggtgtgg ctgacggcaa cgccgctgct    600

cttggagagg tcactccgga gacggcgttg gttttggggt gtggggggtt ggtggcacta    660

tgtggcgcgt ctgtgcgcga cgggctcaga atgtagcccc atgggcggga ctcgaggctc    720

ggtggacggc cttgcaggag gtacccggaa ctccacgagt gacctcgcga tctggcccgg    780

ctcccgctcg tcgcaacagc gtgactacag ggtatggcgg ggtccgggca ctgtgcggct    840

ggacccccag ttctggggcc acgccgcgga accgcttact gctgcagctt ttggggtcgc    900

ccggccgccg ctattacagt cttcccccgc atcagaaggt tccattgcct tctctttccc    960

ccacaatgca ggcaggcacc atagcccgtt gggaaaaaaa agagggggac aaaatcaatg   1020

aaggtgacct aattgcagag gttgaaactg ataaagccac tgttggattt gagagcctgg   1080

aggagtgtta tatggcaaag atacttgttg ctgaaggtac cagggatgtt cccatcggag   1140

cgatcatctg tatcacagtt ggcaagcctg aggatattga ggcctttaaa aattatacac   1200

tggattcctc agcagcacct accccacaag cggccccagc accaacccct gctgccactg   1260

cttcgccacc tacaccttct gctcaggctc ctggtagctc atatccccct cacatgcagg   1320

tacttcttcc tgccctctct cccaccatga ccatgggcac agttcagaga tgggaaaaaa   1380

aagtgggtga gaagctaagt gaaggagact tactggcaga gatagaaact gacaaagcca   1440

ctataggttt tgaagtacag gaagaaggtt atctggcaaa aatcctggtc cctgaaggca   1500

caagagatgt ccctctagga accccactct gtatcattgt agaaaaagag gcagatatat   1560

cagcatttgc tgactatagg ccaaccgaag taacagattt aaaaccacaa gtgccaccac   1620

ctaccccacc cccggtggcc gctgttcctc caactcccca gcctttagct cctacacctt   1680

cagcaccctg cccagctact cctgctggac caaagggaag ggtgtttgtt agccctcttg   1740

caaagaagtt ggcagtagag aaagggattg atcttacaca agtaaaaggg acaggaccag   1800

atggtagaat caccaagaag gatatcgact cttttgtgcc tagtaaagtt gctcctgctc   1860

cggcagctgt tgtgcctccc acaggtcctg gaatggcacc agttcctaca ggtgtcttca   1920

cagatatccc aatcagcaac attcgtcggg ttattgcaca gcgattaatg caatcaaagc   1980

aaaccatacc tcattattac ctttctatcg atgtaaatat gggagaagtt ttgttggtac   2040

ggaaagaact taataagata ttagaaggga gaagcaaaat ttctgtcaat gacttcatca   2100

taaaagcttc agctttggca tgtttaaaag ttcccgaagc aaattcttct tggatggaca   2160

cagttataag acaaaatcat gttgttgatg tcagtgttgc ggtcagtact cctgcaggac   2220

tcatcacacc tattgtgttt aatgcacata taaaaggagt ggaaaccatt gctaatgatg   2280

ttgtttcttt agcaaccaaa gcaagagagg gtaaactaca gccacatgaa ttccagggtg   2340

gcacttttac gatctccaat ttaggaatgt ttggaattaa gaatttctct gctattatta   2400

acccacctca agcatgtatt ttggcaattg gtgcttcaga ggataaactg gtccctgcag   2460

ataatgaaaa agggtttgat gtggctagca tgatgtctgt tacactcagt tgtgatcacc   2520

gggtggtgga tggagcagtt ggagcccagt ggcttgctga gtttagaaag taccttgaaa   2580

aacctatcac tatgttgttg taactaactc aagaatttct aaactctccc aggtcacact   2640

gattcattct taacaagata tttatatgtt attaaacagg tggttctttt tattttaacc   2700

agttattttt attattgagt ctgtccagat aagttattta taatgggcat tactgaattt   2760

ttaaaatgcc gattacaccc aaatattgtg cacatttaat aatcagacac cagattttta   2820

gctctgtact cctaattaag ggacatgtat gtggccttgc ctagcccttt ggtgataagt   2880

acttcctcta ggaaatgtac gataggtaga attgtggttc cctaaagaca agtacataaa   2940

ggtgaccctg atgaaacctt gaagttctga aatttaactg cctaaaatgt tctccttaga   3000

tgtgagagaa agagaaatca gaaaaattaa ttctcttggg ggaagggctt gaattgaagc   3060

tttactttag aatttagccc tggtttgaaa ttttccatta catgatcttg gtttatcatc   3120

gatgggaagg gtagaaaact tcaaggaaaa taagtgaaat tttaaaagtc agcattttct   3180

tagacctctt cagctgattg tttatttttc tatgaattcc tacacatggt tattcccccc   3240

tacttgagat aatctaaata taaaccagct acttgatgta actgagaatt tgtgtggata   3300

tttatttaaa caaatgtgta attttgagta cagaattcaa cagttacctc caaaaaagaa   3360

acattgttaa tataatttaa cagaagttgt gaaactaaaa ttttctaaga ttaactggta   3420

gttcattgta aatgaacata atgaacagaa tttatgactc cactgtggaa aatgctatca   3480

aataactaag gaatatatat ggaataagtg tacatatgta aaatattgtt actagagtta   3540

gatatgtgcc aaagtccatt tatcccaaat cctgtctgaa aaggaggggt acattggtaa   3600

acattttgga gtgcttaaaa atgccaaaaa caaaatggta atttctactt tgataaagta   3660

aaaaagttaa atgtgtgtaa aaaagtgttc tgtgtccttc tactccagca tcgtctcatg   3720

taaaataaga aagccctaaa atactattgg agagaaaaaa ttaactaggt tgctacttta   3780

tttgcctaaa tacttttttc tattttgtta gattttgcct ttcttttgga aggaaggagg   3840

cgatattctg gattataaaa atgaattggg aacattatca caattccaga ctttctatta   3900

atatttatgt gttttaataa acgtttgaaa ttatttatga ctacttaaaa tgaatctgac   3960

cagtgcttcc tggtatatgt aatatgtgga gttagcccct gaaatttgct ttaagtgttt   4020

cagtgttgaa tctgtttcta aatattcatt attacatggt acacaagtga cactccatat   4080

attccacaca gacttttacc ttgctgtatt attatgaaaa caatacatta atttgatttt   4140

tcagtaatta gtaattttag gttgaagatt atccaaaaga aacaagctta tcacaaggga   4200

ccatcatcaa tatgatccaa atctggttca aacattcaaa acttcaaaga taattcatct   4260

ttcgctaatg cttgtggttc tgttgttccc ttgaaaaaaa ataaaaacag ttgccttcta   4320

ataaacattg ttgagttaaa aattaaaaaa aa                                 4352


<210>  532
<211>  3172
<212>  DNA
<213>  Human

<400>  532
agtgctgggc ggggcgctga ctcacccggg cccgggctgg ccggttctta agcggcagcg     60

cgctgcgggc gccgagtgtc gggcgcggca ggaggacgag gcagggcggg cgggcgctct    120

aagggttctg ctctgactcc aggttgggac agcgtcttcg ctgctgctgg atagtcgtgt    180

tttcggggat cgaggatact caccagaaac cgaaaatgcc gaaaccaatc aatgtccgag    240

ttaccaccat ggatgcagag ctggagtttg caatccagcc aaatacaact ggaaaacagc    300

tttttgatca ggtggtaaag actatcggcc tccgggaagt gtggtacttt ggcctccact    360

atgtggataa taaaggattt cctacctggc tgaagctgga taagaaggtg tctgcccagg    420

aggtcaggaa ggagaatccc ctccagttca agttccgggc caagttctac cctgaagatg    480

tggctgagga gctcatccag gacatcaccc agaaactttt cttcctccaa gtgaaggaag    540

gaatccttag cgatgagatc tactgccccc ctgagactgc cgtgctcttg gggtcctacg    600

ctgtgcaggc caagtttggg gactacaaca aagaagtgca caagtctggg tacctcagct    660

ctgagcggct gatccctcaa agagtgatgg accagcacaa acttaccagg gaccagtggg    720

aggaccggat ccaggtgtgg catgcggaac accgtgggat gctcaaagat aatgctatgt    780

tggaatacct gaagattgct caggacctgg aaatgtatgg aatcaactat ttcgagataa    840

aaaacaagaa aggaacagac ctttggcttg gagttgatgc ccttggactg aatatttatg    900

agaaagatga taagttaacc ccaaagattg gctttccttg gagtgaaatc aggaacatct    960

ctttcaatga caaaaagttt gtcattaaac ccatcgacaa gaaggcacct gactttgtgt   1020

tttatgcccc acgtctgaga atcaacaagc ggatcctgca gctctgcatg ggcaaccatg   1080

agttgtatat gcgccgcagg aagcctgaca ccatcgaggt gcagcagatg aaggcccagg   1140

cccgggagga gaagcatcag aagcagctgg agcggcaaca gctggaaaca gagaagaaaa   1200

ggagagaaac cgtggagaga gagaaagagc agatgatgcg cgagaaggag gagttgatgc   1260

tgcggctgca ggactatgag gagaagacaa agaaggcaga gagagagctc tcggagcaga   1320

ttcagagggc cctgcagctg gaggaggaga ggaagcgggc acaggaggag gccgagcgcc   1380

tagaggctga ccgtatggct gcactgcggg ctaaggagga gctggagaga caggcggtgg   1440

atcagataaa gagccaggag cagctggctg cggagcttgc agaatacact gccaagattg   1500

ccctcctgga agaggcgcgg aggcgcaagg aggatgaagt tgaagagtgg cagcacaggg   1560

ccaaagaagc ccaggatgac ctggtgaaga ccaaggagga gctgcacctg gtgatgacag   1620

cacccccgcc cccaccaccc cccgtgtacg agccggtgag ctaccatgtc caggagagct   1680

tgcaggatga gggcgcagag cccacgggct acagcgcgga gctgtctagt gagggcatcc   1740

gggatgaccg caatgaggag aagcgcatca ctgaggcaga gaagaacgag cgtgtgcagc   1800

ggcagctgct gacgctgagc agcgagctgt cccaggcccg agatgagaat aagaggaccc   1860

acaatgacat catccacaac gagaacatga ggcaaggccg ggacaagtac aagacgctgc   1920

ggcagatccg gcagggcaac accaagcagc gcatcgacga gttcgaggcc ctgtaacagc   1980

caggccagga ccaagggcag aggggtgctc atagcgggcg ctgccagccc cgccacgctt   2040

gtgtctttag tgctccaagt ctaggaactc cctcagatcc cagttccttt agaaagcagt   2100

tacccaacag aaacattctg ggctgggaac cagggaggcg ccctggtttg ttttccccag   2160

ttgtaatagt gccaagcagg cctgattctc gcgattattc tcgaatcacc tcctgtgttg   2220

tgctgggagc aggactgatt gaattacgga aaatgcctgt aaagtctgag taagaaactt   2280

catgctggcc tgtgtgatac aagagtcagc atcattaaag gaaacgtggc aggacttcca   2340

tctgtgccat acttgttctg tattcgaaat gagctcaaat tgatttttta atttctatga   2400

aggatccatc tttgtatatt tacatgctta gaggggtgaa aattattttg gaaattgagt   2460

ctgaagcact ctcgcacaca cagtgattcc ctcctcccgt cactccacgc agctggcaga   2520

gagcacagtg atcaccagcg tgagtggtgg aggaggacac ttggattttt ttttttgttt   2580

tttttttttt tgcttaacag ttttagaata cattgtactt atacacctta ttaatgatca   2640

gctatatact atttatatac aagtgataat acagatttgt aacattagtt ttaaaaaggg   2700

aaagttttgt tctgtatatt ttgttacctt ttacagaata aaagaattac atatgaaaaa   2760

ccctctaaac catggcactt gatgtgatgt ggcaggaggg cagtggtgga gctggacctg   2820

cctgctgcag tcacgtgtaa acaggattat tattagtgtt ttatgcatgt aatggactat   2880

gcacactttt aattttgtca gattcacaca tgccactatg agctttcaga ctccagctgt   2940

gaagagactc tgtttgcttg tgtttgtttg tttgcagtct ctctctgcca tggccttggc   3000

aggctgctgg aaggcagctt gtggaggccg ttggttccgc ccactcattc cttctcgtgc   3060

actgctttct ccttcacagc taagatgcca tgtgcaggtg gattccatgc cgcagacatg   3120

aaataaaagc tttgcaaagg cacgaagcaa aaaaaaaaaa aaaaaaaaaa aa           3172


<210>  533
<211>  487
<212>  DNA
<213>  Human

<400>  533
gattattttc tcaggtgttt gcaacagtgt tctaactatt aacgctacga tgcctgaacc     60

taccaagtct gctcctgccc caaagaaggg ctccaagaag gcggtgacta aggctcagaa    120

gaaggacggg aagaagcgca agcgcagccg caaggagagc tattcagtgt atgtgtacaa    180

ggtgctgaag caggtccatc ccgacaccgg catctcttcc aaggcaatgg ggatcatgaa    240

ttccttcgtc aacgacatct tcgagcgcat cgcaggcgag gcttcccgcc tggcgcatta    300

caacaagcgc tcgaccatca cctccaggga gatccagacg gccgtgcgcc tgctgcttcc    360

gggggagctg gccaagcacg ccgtgtcgga gggcaccaag gccgtcacca agtacaccag    420

ttccaagtaa ctttgccaag taagcatctt tacacctaat cccaaaggct cttttaagag    480

ccacgca                                                              487


<210>  534
<211>  1941
<212>  DNA
<213>  Human

<400>  534
gagagggcga aggtaggctg gcagatacgt tcgtcagctt gctcctttct gcccgtggac     60

gccgccgaag aagcatcgtt aaagtctctc ttcaccctgc cgtcatgtct aagtcagagt    120

ctcctaaaga gcccgaacag ctgaggaagc tcttcattgg agggttgagc tttgaaacaa    180

ctgatgagag cctgaggagc cattttgagc aatggggaac gctcacggac tgtgtggtaa    240

tgagagatcc aaacaccaag cgctccaggg gctttgggtt tgtcacatat gccactgtgg    300

aggaggtgga tgcagctatg aatgcaaggc cacacaaggt ggatggaaga gttgtggaac    360

caaagagagc tgtctccaga gaagattctc aaagaccagg tgcccactta actgtgaaaa    420

agatatttgt tggtggcatt aaagaagaca ctgaagaaca tcacctaaga gattattttg    480

aacagtatgg aaaaattgaa gtgattgaaa tcatgactga ccgaggcagt ggcaagaaaa    540

ggggctttgc ctttgtaacc tttgacgacc atgactccgt ggataagatt gtcattcaga    600

aataccatac tgtgaatggc cacaactgtg aagttagaaa agccctgtca aagcaagaga    660

tggctagtgc ttcatccagc caaagaggtc gaagtggttc tggaaacttt ggtggtggtc    720

gtggaggtgg tttcggtggg aatgacaact tcggtcgtgg aggaaacttc agtggtcgtg    780

gtggctttgg tggcagccgt ggtggtggtg gatatggtgg cagtggggat ggctataatg    840

gatttggtaa tgatggtggt tatggaggag gcggccctgg ttactctgga ggaagcagag    900

gctatggaag tggtggacag ggttatggaa accagggcag tggctatggc gggagtggca    960

gctatgacag ctataacaac ggaggcggag gcggctttgg cggtggtagt ggaagcaatt   1020

ttggaggtgg tggaagctac aatgattttg ggaattacaa caatcagtct tcaaattttg   1080

gacccatgaa gggaggaaat tttggaggca gaagctctgg cccctatggc ggtggaggcc   1140

aatactttgc aaaaccacga aaccaaggtg gctatggcgg ttccagcagc agcagtagct   1200

atggcagtgg cagaagattt taattaggaa acaaagctta gcaggagagg agagccagag   1260

aagtgacagg gaagctacag gttacaacag atttgtgaac tcagccaagc acagtggtgg   1320

cagggcctag ctgctacaaa gaagacatgt tttagacaaa tactcatgtg tatgggcaaa   1380

aaactcgagg actgtatttg tgactaattg tataacaggt tattttagtt tctgttctgt   1440

ggaaagtgta aagcattcca acaaagggtt ttaatgtaga tttttttttt tgcaccccat   1500

gctgttgatt gctaaatgta acagtctgat cgtgacgctg aataaatgtc ttttttttaa   1560

tgtgctgtgt aaagttagtc tactcttaag ccatcttggt aaatttcccc aacagtgtga   1620

agttagaatt ccttcagggt gatgccaggt tctatttgga atttatatac aacctgcttg   1680

ggtggagaag ccattgtctt cggaaacctt ggtgtagttg aactgatagt tactgttgtg   1740

acctgaagtt caccattaaa agggattacc caagcaaaat catggaatgg ttataaaagt   1800

gattgttggc acatcctatg caatatatct aaattgaata atggtaccag ataaaattat   1860

agatgggaat gaagcttgtg tatccattat catgtgtaat caataaacga tttaattctc   1920

ttgaaaaaaa aaaaaaaaaa a                                             1941


<210>  535
<211>  3666
<212>  DNA
<213>  Human

<400>  535
agtggggggg aaggttctag aaaagcggcg gcagcggctc tagcggcagt agcagcagcg     60

ccgggtcccg tgcggaggtg ctcctcgcag agttgtttct cgagcagcgg cagttctcac    120

tacagcgcca ggacgagtcc ggttcgtgtt cgtccgcgga gatctctctc atctcgctcg    180

gctgcgggaa atcgggctga agcgactgag tccgcgatgg agagagaaaa ggaacagttc    240

cgtaagctct ttattggtgg cttaagcttt gaaaccacag aagaaagttt gaggaactac    300

tacgaacaat ggggaaagct tacagactgt gtggtaatga gggatcctgc aagcaaaaga    360

tcaagaggat ttggttttgt aactttttca tccatggctg aggttgatgc tgccatggct    420

gcaagacctc attcaattga tgggagagta gttgagccaa aacgtgctgt agcaagagag    480

gaatctggaa aaccaggggc tcatgtaact gtgaagaagc tgtttgttgg cggaattaaa    540

gaagatactg aggaacatca ccttagagat tactttgagg aatatggaaa aattgatacc    600

attgagataa ttactgatag gcagtctgga aagaaaagag gctttggctt tgttactttt    660

gatgaccatg atcctgtgga taaaatcgta ttgcagaaat accataccat caatggtcat    720

aatgcagaag taagaaaggc tttgtctaga caagaaatgc aggaagttca gagttctagg    780

agtggaagag gaggcaactt tggctttggg gattcacgtg gtggcggtgg aaatttcgga    840

ccaggaccag gaagtaactt tagaggagga tctgatggat atggcagtgg acgtggattt    900

ggggatggct ataatgggta tggaggagga cctggaggtg gcaattttgg aggtagcccc    960

ggttatggag gaggaagagg aggatatggt ggtggaggac ctggatatgg caaccagggt   1020

gggggctacg gaggtggtta tgacaactat ggaggaggaa attatggaag tggaaattac   1080

aatgattttg gaaattataa ccagcaacct tctaactacg gtccaatgaa gagtggaaac   1140

tttggtggta gcaggaacat ggggggacca tatggtggag gaaactatgg tccaggaggc   1200

agtggaggaa gtgggggtta tggtgggagg agccgatact gagcttcttc ctatttgcca   1260

tgggcttcac tgtataaata ggagaggatg agagcccaga ggtaacagaa cagcttcagg   1320

ttatcgaaat aacaatgtta aggaaactct tatctcagtc atgcataaat atgcagtgat   1380

atggcagaag acaccagagc agatgcagag agccattttg tgaatggatt ggattattta   1440

ataacattac cttactgtgg aggaaggatt gtaaaaaaaa atgcctttga gacagtttct   1500

tagcttttta attgttgttt ctttctagtg gtctttgtaa gagtgtagaa gcattccttc   1560

tttgataatg ttaaatttgt aagtttcagg tgacatgtga aacctttttt aagatttttc   1620

tcaaagtttt gaaaagctat tagccaggat catggtgtaa taagacataa cgtttttcct   1680

ttaaaaaaat ttaagtgcgt gtgtagagtt aagaagctgt tgtacattta tgatttaata   1740

aaataattct aaaggaaatt gtgtaattat agacttttta ttttaaataa gttaaggagt   1800

gggtagtata attaaggtcc gttgcaaagc tgttgttata tttgtataag ataaatgctg   1860

gtcagatgta agtgtgttgt ctgcaattca tcaggattaa attatgtaga taacttaagg   1920

gatatctctg caaggagaaa caccttttta gatcttttag atgctgcttc ttcaatgcaa   1980

ggaaaggaaa taaccccagc gaggtactct tcagggacac aggtctagta caagagaact   2040

cttgacggct actaagttca gccagtctta aaaaactgtg ctgtttctac aaaactttaa   2100

ctacagtagt ttataaggat gccaacgaaa gctgagggtg tagagcaaaa tagttctaag   2160

cttcagttaa acttctttag gtaagatctt atttactttt cctttcttaa ttttcctccc   2220

taaaagataa actaatactc ttaaatggtc tttcagtata gtggttctta cgtagtttaa   2280

catagctata aattgagttt aacaatttat aaactcaaga gaataatttt tataaaccct   2340

gttttccaat ctgtcattta cttaaattat tttggttgtt tttccctttt tttccttctt   2400

ttcccacccc ctccccctcc atgtgaagat ttgggtgctt aacatatcat ttttttccct   2460

gccggaattt tagcattgat atgaaccatg gacaagtata ttctgctgcc acaaagactg   2520

taaagtgctt catttcaaca gctgaggcaa gccaagtgat cattaataaa gcttttcttg   2580

gttccttcag tggtgttggt agtaaaatgg taggtaaaag ttaggctgca agttcaataa   2640

atcatgagat ttcccatcgt tacacccttg tgtattcaca tttcttggat caaacatttt   2700

gagtgaacta ggggttttta ttaaagacat ttgttgtatt tatggttgta actgtacatg   2760

cttatcagga tgagactgaa agaaggtagg gcaaaaatgg ttgaatctat tttcagatag   2820

tagttcatac ttgagtgaag tgtcttgtct gcattatgaa gcctggtatg tatccagtac   2880

taaataggtg ggttaaatgt ggtaattcta gttcagtgtc ttaccctgaa gagaaagttg   2940

taggttggct gttgaaattc attccttaga tatgatcagt ttgattgccc ggctttattg   3000

cctttacagg aatgtgatac tcagggctta ctctatacac caatgagtct tctttgatcc   3060

taagaccacc actgaagttg tttaggttct tttggacaaa catgataaac ttcttcagat   3120

actttttttt tcctttggca ggaaggtgtc ttgctgcagg taactaatga agaagtggtc   3180

aaccacagag tcttcaagaa ataagaaatt ctgtaccatc tgaaagtagt tcttgttggt   3240

gccttcattt aaaaagcact ctttaaaata aaagggaaat gttttctgat aaaacaaaca   3300

tttagttgag gttcttgata taaaacaatt acaaaatgag tgttgtttgt aaaacagtaa   3360

catcaaattg gctagagaga taaatgtatc atgttttaaa ttaggttttg tgagtagaca   3420

gattacaatt ctattttaaa tataaagttt ataaaataaa tactttttgt atccaaatac   3480

ttggtgtaat gtttacacat aaaatgtgtg aatcttgttc tataaatatt tggttgtcta   3540

aaagatcacc atcccctaaa tttttaaaag cagtttcaca aagctatgca tattttaata   3600

ttaacaggta aatgagaaga gcattgtgga cattattggc tgtccccaat aaaatgctgt   3660

tcatta                                                              3666


<210>  536
<211>  2943
<212>  DNA
<213>  Human

<400>  536
aactcccaag ccccacccct gggcttggcc tgccttgccc tgccgggaag tgatccccaa     60

ggcagggtga gagttcccca tctgaggcgt ttgttgcagc tacctgcact tctagatgct    120

ccccaggttc atcctgtgtc gtctccccca cctaccagtc atcttcttgt gagccctggg    180

cttaggagtc accatggcaa ctgaagagtt catcatccgc atccccccat accactatat    240

ccatgtgctg gaccagaaca gcaacgtgtc ccgtgtggag gtcgggccaa agacctacat    300

ccggcaggac aatgagaggg tactgtttgc ccccatgcgc atggtgaccg tccccccacg    360

tcactactgc acagtggcca accctgtgtc tcgggatgcc cagggcttgg tgctgtttga    420

tgtcacaggg caagttcggc ttcgccacgc tgacctcgag atccggctgg cccaggaccc    480

cttccccctg tacccagggg aggtgctgga aaaggacatc acacccctgc aggtggttct    540

gcccaacact gccctccatc taaaggcgct gcttgatttt gaggataaag atggagacaa    600

ggtggtggca ggagatgagt ggcttttcga gggacctggc acgtacatcc cccggaagga    660

agtggaggtc gtggagatca ttcaggccac catcatcagg cagaaccagg ctctgcggct    720

cagggcccgc aaggagtgct gggaccggga cggcaaggag agggtgacag gggaagaatg    780

gctggtcacc acagtagggg cgtacctccc agcggtgttt gaggaggttc tggatttggt    840

ggacgccgtc atccttacgg aaaagacagc cctgcacctc cgggctcggc ggaacttccg    900

ggacttcagg ggagtgtccc gccgcactgg ggaggagtgg ctggtaacag tgcaggacac    960

agaggcccac gtgccagatg tccacgagga ggtgctgggg gttgtgccca tcaccaccct   1020

gggcccccac aactactgcg tgattctcga ccctgtcgga ccggatggca agaatcagct   1080

ggggcagaag cgcgtggtca agggagagaa gtcttttttc ctccagccag gagagcagct   1140

ggaacaaggc atccaggatg tgtatgtgct gtcggagcag caggggctgc tgctgagggc   1200

cctgcagccc ctggaggagg gggaggatga ggagaaggtc tcacaccagg ctggggacca   1260

ctggctcatc cgcggacccc tggagtatgt gccatctgcc aaagtggagg tggtggagga   1320

gcgccaggcc atccctctag acgagaacga gggcatctat gtgcaggatg tcaagaccgg   1380

aaaggtgcgc gctgtgattg gaagcaccta catgctgacc caggacgaag tcctgtggga   1440

gaaagagctg cctcccgggg tggaggagct gctgaacaag gggcaggacc ctctggcaga   1500

caggggtgag aaggacacag ctaagagcct ccagcccttg gcgccccgga acaagacccg   1560

tgtggtcagc taccgcgtgc cccacaacgc tgcggtgcag gtgtacgact accgagagaa   1620

gcgagcccgc gtggtcttcg ggcctgagct ggtgtcgctg ggtcctgagg agcagttcac   1680

agtgttgtcc ctctcagctg ggcggcccaa gcgtccccat gcccgccgtg cgctctgcct   1740

gctgctgggg cctgacttct tcacagacgt catcaccatc gaaacggcgg atcatgccag   1800

gctgcaactg cagctggcct acaactggca ctttgaggtg aatgaccgga aggaccccca   1860

agagacggcc aagctctttt cagtgccaga ctttgtaggt gatgcctgca aagccatcgc   1920

atcccgggtg cggggggccg tggcctctgt cactttcgat gacttccata agaactcagc   1980

ccgcatcatt cgcactgctg tctttggctt tgagacctcg gaagcgaagg gccccgatgg   2040

catggccctg cccaggcccc gggaccaggc tgtcttcccc caaaacgggc tggtggtcag   2100

cagtgtggac gtgcagtcag tggagcctgt ggatcagagg acccgggacg ccctgcaacg   2160

cagcgtccag ctggccatcg agatcaccac caactcccag gaagcggcgg ccaagcatga   2220

ggctcagaga ctggagcagg aagcccgcgg ccggcttgag cggcagaaga tcctggacca   2280

gtcagaagcc gagaaagctc gcaaggaact tttggagctg gaggctctga gcatggccgt   2340

ggagagcacc gggactgcca aggcggaggc cgagtcccgt gcggaggcag cccggattga   2400

gggagaaggg tccgtgctgc aggccaagct aaaagcacag gccttggcca ttgaaacgga   2460

ggctgagctc cagagggtcc agaaggtccg agagctggaa ctggtctatg cccgggccca   2520

gctggagctg gaggtgagca aggctcagca gctggctgag gtggaggtga agaagttcaa   2580

gcagatgaca gaggccatag gccccagcac catcagggac cttgctgtgg ctgggcctga   2640

gatgcaggta aaactgctcc agtccctggg cctgaaatca accctcatca ccgatggctc   2700

cactcccatc aacctcttca acacagcctt tgggctgctg gggatggggc ccgagggtca   2760

gcccctgggc agaagggtgg ccagtgggcc cagccctggg gaggggatat ccccccagtc   2820

tgctcaggcc cctcaagctc ctggagacaa ccacgtggtg cctgtactgc gctaactcct   2880

gattaataca atggaagttt ctgggcattt acaatttcaa cacttaaaaa aaaaaaaaaa   2940

aaa                                                                 2943


<210>  537
<211>  1229
<212>  DNA
<213>  Human

<400>  537
gtctgacggg cgatggcgca gccaatagac aggagcgcta tccgcggttt ctgattggct     60

actttgttcg cattataaaa ggcacgcgcg ggcgcgaggc ccttctctcg ccaggcgtcc    120

tcgtggaagt gacatcgtct ttaaaccctg cgtggcaatc cctgacgcac cgccgtgatg    180

cccagggaag acagggcgac ctggaagtcc aactacttcc ttaagatcat ccaactattg    240

gatgattatc cgaaatgttt cattgtggga gcagacaatg tgggctccaa gcagatgcag    300

cagatccgca tgtcccttcg cgggaaggct gtggtgctga tgggcaagaa caccatgatg    360

cgcaaggcca tccgagggca cctggaaaac aacccagctc tggagaaact gctgcctcat    420

atccggggga atgtgggctt tgtgttcacc aaggaggacc tcactgagat cagggacatg    480

ttgctggcca ataaggtgcc agctgctgcc cgtgctggtg ccattgcccc atgtgaagtc    540

actgtgccag cccagaacac tggtctcggg cccgagaaga cctccttttt ccaggcttta    600

ggtatcacca ctaaaatctc caggggcacc attgaaatcc tgagtgatgt gcagctgatc    660

aagactggag acaaagtggg agccagcgaa gccacgctgc tgaacatgct caacatctcc    720

cccttctcct ttgggctggt catccagcag gtgttcgaca atggcagcat ctacaaccct    780

gaagtgcttg atatcacaga ggaaactctg cattctcgct tcctggaggg tgtccgcaat    840

gttgccagtg tctgtctgca gattggctac ccaactgttg catcagtacc ccattctatc    900

atcaacgggt acaaacgagt cctggccttg tctgtggaga cggattacac cttcccactt    960

gctgaaaagg tcaaggcctt cttggctgat ccatctgcct ttgtggctgc tgcccctgtg   1020

gctgctgcca ccacagctgc tcctgctgct gctgcagccc cagctaaggt tgaagccaag   1080

gaagagtcgg aggagtcgga cgaggatatg ggatttggtc tctttgacta atcaccaaaa   1140

agcaaccaac ttagccagtt ttatttgcaa aacaaggaaa taaaggctta cttctttaaa   1200

aagtaaaaaa aaaaaaaaaa aaaaaaaaa                                     1229


<210>  538
<211>  512
<212>  DNA
<213>  Human

<400>  538
cctttcctca gctgccgcca aggtgctcgg tccttccgag gaagctaagg ctgcgttggg     60

gtgaggccct cacttcatcc ggcgactagc accgcgtccg gcagcgccag ccctacactc    120

gcccgcgcca tggcctctgt ctccgagctc gcctgcatct actcggccct cattctgcac    180

gacgatgagg tgacagtcac ggaggataag atcaatgccc tcattaaagc agccggtgta    240

aatgttgagc ctttttggcc tggcttgttt gcaaaggccc tggccaacgt caacattggg    300

agcctcatct gcaatgtagg ggccggtgga cctgctccag cagctggtgc tgcaccagca    360

ggaggtcctg ccccctccac tgctgctgct ccagctgagg agaagaaagt ggaagcaaag    420

aaagaagaat ccgaggagtc tgatgatgac atgggctttg gtctttttga ctaaacctct    480

tttataacat gttcaataaa aagctgaact tt                                  512


<210>  539
<211>  511
<212>  DNA
<213>  Human

<400>  539
ggtttaaccc cgcctcttgc gtcggcgcct tccttttcct ccctgtcgcc accgaggtcg     60

cacgcgtgag acttctccgc cgcctccgcc gcagacgccg ccgcgatgcg ctacgtcgcc    120

tcctacctgc tggctgccct agggggcaac tcctccccca gcgccaagga catcaagaag    180

atcttggaca gcgtgggtat cgaggcggac gacgaccggc tcaacaaggt tatcagtgag    240

ctgaatggaa aaaacattga agacgtcatt gcccagggta ttggcaagct tgccagtgta    300

cctgctggtg gggctgtagc cgtctctgct gccccaggct ctgcagcccc tgctgctggt    360

tctgcccctg ctgcagcaga ggagaagaaa gatgagaaga aggaggagtc tgaagagtca    420

gatgatgaca tgggatttgg cctttttgat taaattcctg ctcccctgca aataaagcct    480

ttttacacat ctcaaaaaaa aaaaaaaaaa a                                   511


<210>  540
<211>  4454
<212>  DNA
<213>  Human

<400>  540
agaataattt tgctgccaag tgaatcagag agacttgcag ttctcggaga gcacggaact     60

tattcctgcc cagagttcag acacagccag aaattaccat ttcatacttc acagaatgga    120

ggtttcagca gccaaagccc caagtgccgc agacttgtct gagattgaaa taaagaaaga    180

gatgaagaaa gaccctctca ccaacaaagc tccagaaaag cccctgcacg aagtgcccag    240

tggaaactct ttgctgtctt ctgaaacgat tttaagaacc aataagagag gcgagcgacg    300

gaggcgccgg tgccaggtgg cattcagcta cctgccccag aatgacgatg aacttgagct    360

gaaagttggc gacatcatag aggtggtagg agaggtagag gaaggatggt gggaaggtgt    420

tctcaacggg aagactggaa tgtttccttc caacttcatc aaggagctgt caggggagtc    480

ggatgagctt ggcatttccc aggatgagca gctatccaag tcaagtttaa gggaaaccac    540

aggctccgag agtgatgggg gtgactcaag cagcaccaag tctgaaggtg ccaacgggac    600

agtggcaact gcagcaatcc agcccaagaa agttaaggga gtgggctttg gagacatttt    660

caaagacaag ccaatcaaac taagaccaag gtcaattgaa gtagaaaatg actttctgcc    720

ggtagaaaag actattggga agaagttacc tgcaactaca gcaactccag actcatcaaa    780

aacagaaatg gacagcagga caaagagcaa ggattactgc aaagtaatat ttccatatga    840

ggcacagaat gatgatgaat tgacaatcaa agaaggagat atagtcactc tcatcaataa    900

ggactgcatc gacgtaggct ggtgggaagg agagctgaac ggcagacgag gcgtgttccc    960

cgataacttc gtgaagttac ttccaccgga ctttgaaaag gaagggaata gacccaagaa   1020

gccaccgcct ccatccgctc ctgtcatcaa acaaggggca ggcaccactg agagaaaaca   1080

tgaaattaaa aagatacctc ctgaaagacc agaaatgctt ccaaacagaa cagaagaaaa   1140

agaaagacca gagagagagc caaaactgga tttacagaag ccctccgttc ctgccatacc   1200

gccaaaaaag cctcggccac ctaagaccaa ttctctcagc agacctggcg cactgccccc   1260

gagaaggccg gagagaccgg tgggtccgct gacacacacc aggggtgaca gtccaaagat   1320

tgacttggcc ggcagttcgc tatctggcat cctggacaaa gatctctcgg accgcagcaa   1380

tgacattgac ttagaaggtt ttgactccgt ggtatcatct actgagaaac tcagtcatcc   1440

gaccacaagc agaccaaaag ctacagggag gcggcctccg tcccagtccc tcacatcttc   1500

atccctttca agccctgata tcttcgactc cccaagtccc gaagaggata aggaggaaca   1560

catttcactt gcgcacagag gagtggacgc gtcaaagaaa acttccaaga ctgttaccat   1620

atcccaagtg tctgacaaca aagcatccct gccgcccaag ccggggacca tggcagcagg   1680

tggcggtggg ccagcccctc tgtcctcagc ggcgccctcc cccctgtcat cctctttggg   1740

aacagctgga cacagagcca actccccgtc tctgttcggc acggaaggaa aaccaaagat   1800

ggagcctgcg gccagcagcc aggcggccgt ggaggagcta aggacacagg tccgcgagct   1860

gaggagcatc atcgagacca tgaaggacca gcagaaacga gagattaaac agttattgtc   1920

tgagttggat gaagagaaga aaatccggct tcggttgcag atggaagtga acgacataaa   1980

gaaagctcta caatcaaaat gaatacttga tcaatgaaat gtcacattat tcatcctgag   2040

tccgagactc aaattttctg ccccagccaa aataatcttg tgccaaaaga ttaaaggttt   2100

gcctcaaaat gtccctgttt gaaagattag cacaaaagtc ttgatagcac aacacaaatt   2160

ccatccaaga ggagaatctt ccccagggtt tagtcctggg gctggcactc gttgtgactt   2220

acacagagca aaattgtgct aaaggctttt ctactctgag atctcaatgc gaaatgaaaa   2280

ctcaggcagt ttagtccata gtggtactat tttgatgata ttttccatta ataaaatgta   2340

atttcagatt attcgtttac aagctttata attttatgat tttttaatcg tgttttgtca   2400

cagacttccc tagtgtttgt actacacgta gtcagaagcg agtgtccttt tcttttgctt   2460

caggctaaga gctgcctcgc tctttgtccc cccattagga ttctattaca tatgcaattg   2520

taggttcaac ctgtcccttt ccctgccagc aaaccccacc accctaagag aaattttagc   2580

ttatatatga cggtatattt acaaaaagag aaagagaaaa tctggtattt gcaatgatct   2640

gtgccttctt tttaccaccc tcttgattgg agcttttgtg atgcagctac catgattcaa   2700

aaaaattaaa aattaaaaaa aaaaaatctg ccacttatcc aagtccacta gaggccactg   2760

tcttcaaagc ttctctcacc ctagccaaag gtcctaagag gagacagctg tgaagttggg   2820

cgtgctctgt ggtaccagct gtgacttttc tatttctcct agttttaggt tgttcatgaa   2880

actagaaatg tcatcctgct tgatttttca tcagccaagt taaacccctg ctttctgtcc   2940

tttgcacctt ttgcgtgaac agaatatgca ttattaaagc aaaaataaat aaaagtaaaa   3000

tgcaaatgaa aacaagggag ggaaagttgt attatttcct gcactgggtt acccgtgtgt   3060

gttatcgttt aaactgtatt cacataatgt catttgcctt gctcacttgt aaccccttcc   3120

tcaggtccaa gagaatggga ggagggtcat gttgaagtgt agccactgga actttcttgc   3180

atttatggag ttgctttttc tttcccaagg aaactgatgt ttgcctgtcc gctttatctt   3240

tgtagtacat gaacagttca gccttagact atgtaactgt tttctcatcc ttagctgaaa   3300

atgaggggcc tactgtattg cgagactgtt caggggtagg ggtggagggg gtggtccctt   3360

aatggcccct gaagatgttg gatgtgtttc tcaaaagctg ctttgtctct ttcctgagtt   3420

taatagtgaa actactaaac attaatagat ttgcacagcc acaaagaatg agagttgata   3480

ataccgaaga agtgatgcaa aaacaaaaaa tcacattact gatcattgat agtattacaa   3540

ataaatgtct cttcctttct cttcctccct tcctccccct gccttcctct taacctatgt   3600

gctcatcctt gctacttgag gctgttattt ccctccgagt atttaaggag cccaaacacc   3660

ttggtcttcc tgggtggggg cataattaag ggaagggagt gtataaggaa ggaaacctca   3720

taccctccat tcccatccct ggatatattg ccttttcagc agcctcgggt tcagtgtgct   3780

tggggtcagg agtgccaggt tcccaagagc agcgtaaaac atccctgtac cccttgacag   3840

ttataagcat ttctgcgtta aacttgaaga ttccagagat tccccacgac ctaatgatct   3900

aagaatgcag attggattct ttgatgttca aatttctcat ttacttatga aaatccctaa   3960

ttatatagtt ttatataatg tgtatacaga gtaggattgt tgatgaaatt gagcggttgg   4020

aacaccctca tggaacactg gcaacatgga atgtagagag ctgatgtctt ccccctcata   4080

gaggccattg gcttcctttg tataaggaga gggagaagtg attctggaag gagaagttgg   4140

tatgtctagc ttcattgcgg cccctcgggc tacccagcaa gaggattctg catcaaggaa   4200

ctggacgagc cgctacccaa actgccacca tctttactct ttacaaaatg gacccatcga   4260

gaatgttgaa aagcttggaa gtatcacttt tgaaaaaaaa aaaaattatt ttgcattcag   4320

catggactcg accaggcatc tatggagatt atttttttgc ttcattttat aaagttgtat   4380

ttagaaaagt cttaagtatt gtgctttgta aagaagatga ttaaaatgaa attttgtgag   4440

aatagttttg ttca                                                     4454


<210>  541
<211>  1940
<212>  DNA
<213>  Human

<400>  541
gcggttcggc gcggaaagcg ggaggtggag gggcggcttg gggcaagcgc gcgcgcgcag     60

tgcagaagcc agccccccgc ggctgaggta ctcaaggtgc ccaaaggcgg ggtagtgacc    120

tcgcgcgtgc gctgtgcccg cggcagcgcc gggtcctagt gtgtgggttg ttgttggcac    180

cgcacggcgc gtgcgcagtg aggacggcgg agggatttgc ggccgggacc caccccctgc    240

tccagtcgct atcggaggcc gcgcgggtgg ctgagcagcg gcctggtgcg ctcgcttagc    300

gggcgacgga atcagacgga cgtggacgcc cccggagtgg aagccgaagc aggagttgtt    360

gttgctgagg ggctgccgca gccgccgcga gcctccggac agacgccaga gcgaggaggg    420

cgctacgcga cttggcaaga tgacccagtt cctgccgccc aaccttctgg ccctctttgc    480

cccccgtgac cctattccat acctgccacc cctggagaaa ctgccacatg aaaaacacca    540

caatcaacct tattgtggca ttgcgccgta cattcgagag tttgaggacc ctcgagatgc    600

ccctcctcca actcgtgctg aaacccgaga ggagcgcatg gagaggaaaa gacgggaaaa    660

gattgagcgg cgacagcaag aagtggagac agagcttaaa atgtgggacc ctcacaatga    720

tcccaatgct cagggggatg ccttcaagac tctcttcgtg gcgagagtga attatgacac    780

aacagaatcc aagctccgga gagagtttga ggtgtacgga cctatcaaaa gaatacacat    840

ggtctacagt aagcggtcag gaaagccccg tggctatgcc ttcatcgagt acgaacacga    900

gcgagacatg cactccgctt acaaacacgc agatggcaag aagattgatg gcaggagggt    960

ccttgtggac gtggagaggg gccgaaccgt gaagggctgg aggccccggc ggctaggagg   1020

aggcctcggt ggtaccagaa gaggaggggc tgatgtgaac atccggcatt caggccgcga   1080

tgacacctcc cgctacgatg agaggcccgg cccctccccg cttccgcaca gggaccggga   1140

ccgggaccgt gagcgggagc gcagagagcg gagccgggag cgagacaagg agcgagaacg   1200

gcgacgctcc cgctcccggg accggcggag gcgctcacgg agtcgcgaca aggaggagcg   1260

gaggcgctcc agggagcgga gcaaggacaa ggaccgggac cggaagcggc gaagcagccg   1320

gagtcgggag cgggcccggc gggagcggga gcgcaaggag gagctgcgtg gcggcggtgg   1380

cgacatggcg gagccctccg aggcgggtga cgcgccccct gatgatgggc ctccagggga   1440

gctcgggcct gacggccctg acggtccaga ggaaaagggc cgggatcgtg accgggagcg   1500

acggcggagc caccggagcg agcgcgagcg gcgccgggac cgggatcgtg accgtgaccg   1560

tgaccgcgag cacaaacggg gggagcgggg cagtgagcgg ggcagggatg aggcccgagg   1620

tgggggcggt ggccaggaca acgggctgga gggtctgggc aacgacagcc gagacatgta   1680

catggagtct gagggcggcg acggctacct ggctccggag aatgggtatt tgatggaggc   1740

tgcgccggag tgaagaggtc gtcctctcca tctgctgtgt ttggacgcgt tcctgcccag   1800

ccccttgctg tcatcccctc ccccaacctt ggccacttga gtttgtcctc caagggtagg   1860

tgtctcattt gttctggccc cttggattta aaaataaaat taatttcctg ttgatagtgg   1920

gcaaaaaaaa aaaaaaaaaa                                               1940


<210>  542
<211>  1153
<212>  DNA
<213>  Human

<400>  542
aactccaggg ctagtgagct ggaccggaag taggtttcta cccgaccgca ttttacgtgg     60

tgctgcattt ccggtagcgg cggcgggaaa tcggctgtgg gagagaggct aggcctctga    120

ggaggcgaat ccggcgggta tcagagccat cagaaccgcc accatgacgg tgggcaagag    180

cagcaagatg ctgcagcata ttgattacag gatgaggtgc atcctgcagg acggccggat    240

cttcattggc accttcaagg cttttgacaa gcacatgaat ttgatcctct gtgactgtga    300

tgagttcaga aagatcaagc caaagaactc caaacaagca gaaagggaag agaagcgagt    360

cctcggtctg gtgctgctgc gaggggagaa tctggtctca atgacagtag agggacctcc    420

tcccaaagat actggtattg ctcgagttcc acttgctgga gctgccgggg gcccagggat    480

cggcagggct gctggcagag gaatcccagc tggggttccc atgccccagg ctcctgcagg    540

acttgctggg ccagtccgtg gggttggcgg gccatcccaa caggtgatga ccccacaagg    600

aagaggtact gttgcagccg ctgcagctgc tgccacagcc agtattgccg gggctccaac    660

ccagtaccca cctggccgtg ggggtcctcc cccacctatg ggccgaggag caccccctcc    720

aggcatgatg ggcccacctc ctggtatgag acctcctatg ggtcccccaa tggggatccc    780

ccctggaaga gggactccaa tgggcatgcc ccctccggga atgcggcctc ctccccctgg    840

gatgcgaggc cttctttgac ccttggccac agagtatgga agtagctccg cagaggcgtg    900

ggctcgattc ctcagggcca cgttaccaca gacctgtttg tttcttatgc tgttgttcgt    960

ggagtctcat gggattgtct ggtttccctt acagggcccc ctcccccggg aatgcgccca   1020

ccaaggccct agactcatct tggccctcct cagctccctg cctgtttccc gtaaggctgt   1080

acatagtcct tttatctcct tgtggcctat gaaactggtt tataataaac tcttaagaga   1140

acattataat tgc                                                      1153


<210>  543
<211>  1326
<212>  DNA
<213>  Human

<400>  543
cagagtggag cggccgccgg agatgcctga cgcatctgtc tgaggagcgg tcagtgacgc     60

gatggagcgg gcaagggatc gcttacacct gagacgaact acagaacagc acgtaccaga    120

ggtggaagtc caagtcaaac gcagaaggac tgcctcactg agcaaccaag agtgtcagtt    180

gtacccgagg cgttctcagc agcagcaagt acctgtggtg gatttccagg ctgaactgag    240

gcaggcattc ttagctgaga caccaagagg tggttaaagc catattggag tagcgaggaa    300

tctgattcca agcaaaaacc aggctccatc tactctttga agcttctgcc cagcttgcat    360

tgtttctagg agaacctgcg tcataccttt atctatagcc ttcccctagg tcttcagaag    420

catcaagttt taactgtgga cattggattt ggtggaacag caatcatgac tgttggcaag    480

agtagcaaga tgctgcagca cattgactat agaatgagat gtatcctgca agatggccga    540

atcttcattg gcacctttaa ggcttttgac aagcatatga atttgatcct ctgtgattgt    600

gatgagttca gaaagatcaa gccaaagaat gcgaagcaac cagagcgtga agaaaagcgg    660

gttttgggtc tggtgttgct gcgtggggag aacttggtat ccatgactgt ggaggggcca    720

ccccccaaag atactggcat tgctcgggta ccacttgctg gagctgctgg aggccctggg    780

gttggtaggg cagctggtag aggagtacca gctggtgtgc caattcccca ggcccctgct    840

ggattggcag gccctgtccg aggagttggg ggaccatccc agcaggtaat gactccacag    900

ggaagaggca ctgtagcagc tgctgctgtt gctgcgactg ccagtattgc tggagcccca    960

acacagtacc caccaggacg gggcactccg cccccacccg tcggcagagc aaccccacct   1020

ccaggcatta tggctcctcc acctggtatg agaccaccca tgggcccacc aattgggctt   1080

ccccctgctc gagggacgcc aataggcatg ccgcctccgg gaatgagacc ccctccacca   1140

ggcattagag gtccacctcc cccaggaatg cgtccaccaa gaccttagca tactgttgat   1200

ccatctcagt cactttttcc cctgcaatgc gtcttgtgaa attgtgtaga gtgtttgtga   1260

gctttttgtt ccctcattct gcattaataa tagctaataa taaatgcata gagcaattaa   1320

actgtg                                                              1326


<210>  544
<211>  2050
<212>  DNA
<213>  Human

<400>  544
agacgctgtg gtctcacctg tcctggcaag gggcctctgc cggctgttcc catgactggc     60

tcagggtctg agttcttatt ccatcaacct tgatcaaaag aaggaaaggg aagaaaaagg    120

cccagggagg ctgaatgaat gtatttcacc agtagcaaat gagatgaacc atcttcctgc    180

acacagccac gatttgcaaa ggtttttgga gaggaataaa tttaatgaaa gatgtacatg    240

acttctaaaa actataagca gtgctgggta aaattaaaca catgatgttc acggaagacc    300

agggtgtaga tgacaggctg ctctatgaca ttgtattcaa gcacttcaaa agaaataagg    360

tggagatttc aaatgcaata aaaaagacat ttccattcct cgagggcctc cgtgatcgtg    420

atctcatcac aaataaaatg tttgaagatt ctcaagattc ttgtagaaac ctggtccctg    480

tacagagagt ggtgtacaat gttcttagtg aactggagaa gacatttaac ctgccagttc    540

tggaagcact gttcagcgat gtcaacatgc aggaataccc cgatttaatt cacatttata    600

aaggctttga aaatgtaatc catgacaaat tgcctctcca agaaagtgaa gaagaagaga    660

gggaggagag gtctggcctc caactaagtc ttgaacaagg aactggtgaa aactcttttc    720

gaagcctgac ttggccacct tcgggttccc catctcatgc tggtacaacc ccacctgaaa    780

atggactctc agagcacccc tgtgaaacag aacagataaa tgcaaagaga aaagatacaa    840

ccagtgacaa agatgattcg ctaggaagcc aacaaacaaa tgaacaatgt gctcaaaagg    900

ctgagccaac agagtcctgc gaacaaattg ctgtccaagt gaataatggg gatgctggaa    960

gggagatgcc ctgcccgttg ccctgtgatg aagaaagccc agaggcagag ctacacaacc   1020

atggaatcca aattaattcc tgttctgtgc gactggtgga tataaaaaag gaaaagccat   1080

tttctaattc aaaagttgag tgccaagccc aagcaagaac tcatcataac caggcatctg   1140

acataatagt catcagcagt gaggactctg aaggatccac tgacgttgat gagcccttag   1200

aagtcttcat ctcagcaccg agaagtgagc ctgtgatcaa taatgacaac cctttagaat   1260

caaatgatga aaaggagggc caagaagcca cttgctcacg accccagatt gtaccagagc   1320

ccatggattt cagaaaatta tctacattca gagaaagttt taagaaaaga gtgataggac   1380

aagaccacga cttttcagaa tccagtgagg aggaggcgcc cgcagaagcc tcgagcgggg   1440

cactgagaag caagcatggt gagaaggctc ctatgacttc tagaagtaca tctacttgga   1500

gaatacccag caggaagaga cgtttcagca gtagtgactt ttcagacctg agtaatggag   1560

aagagcttca ggaaacctgc agctcatccc taagaagagg gtcaggtaaa gaagattagg   1620

atgccaagac ttggcctgca gaatgtcagg aatgtgaatt aaaagctgct gtttccagac   1680

gctttttatt ctgagcacct tcactacctt gtatccagtt catctgggaa ctcctttttg   1740

cattttagaa aatggaaaga ggcaggaaat tatgataaac tcatgtttaa cagaaagagt   1800

ttcactgact aaatgtatgt aattatattt tgttgttgta gaagaaataa atagcaaatt   1860

tgtggtattc ttttttttaa acctgctctc attcctatta acactaagat cttagatttt   1920

tatagtgata aatgggttga catcattgtc atttgtaatt gtaaagcctc aaaagacaac   1980

tgttcctact atgtaattat agacagaaat aaaaacttca gatcaaacac tctcaaacgt   2040

taaaaaaaaa                                                          2050


<210>  545
<211>  10074
<212>  DNA
<213>  Human

<400>  545
cagggatcct tccatgaaga ctgaggcagg cggagctgct aagagcctgc tgacatgaca     60

tcggccacag agtttgaaaa tgtgggcaac cagccacctt acagcaggat caatgcccgc    120

tgggacgccc cagacgacga gctggataat gacaacagct cagccaggct ctttgagagg    180

tcccggataa aggccttggc agatgagcgg gaagttgttc agaaaaagac cttcacgaaa    240

tgggtgaact cgcacctggc tcgagtgtcc tgccgcatca ccgatctcta caaggacctg    300

cgggatgggc gcatgctcat caagctgctg gaggtgctct ctggagagat gctgccaaag    360

cccaccaagg ggaagatgcg catccactgc ctggagaatg tggacaaggc tctccagttc    420

ctcaaggagc agcgtgtaca cctggagaac atgggctccc acgacattgt agatggcaac    480

caccgcctgg tcctgggcct catctggacc atcatcctcc gcttccagat tcaggacatt    540

gtggtccaaa ctcaggaagg tcgtgaaaca cgctcagcca aggatgcgtt gctgttgtgg    600

tgtcagatga agacggcagg ctaccctcat gttaatgtca ccaactttac ctccagctgg    660

aaggatggct tggcctttaa tgccctgata cacaagcacc ggcccgacct gatcgacttt    720

gataagctga aggactccaa tgcccggcac aacctggagc acgcattcaa tgtggctgag    780

cgccagctgg gcatcatccc gctcctcgac cccgaagatg tctttacgga aaaccctgat    840

gagaaatcca tcatcaccta tgtggtggcc ttttaccact acttctccaa gatgaaggtg    900

ctggcagtgg agggcaagcg tgtcggcaag gttattgacc atgccattga gactgagaag    960

atgattgaaa agtacagcgg gctagcctcg gacctgctca cctggatcga gcagaccatc   1020

actgtcctga acagccgcaa gtttgccaac tcgctgacgg gcgtccagca gcagctgcag   1080

gccttcagca cctaccgcac cgtggagaag ccgcccaagt ttcaagagaa ggggaatctg   1140

gaagttctac tttttaccat ccagtcccgg atgagagcca acaatcagaa agtgtacaca   1200

ccccacgatg ggaaactagt gtctgacatc aacagggcct gggaaagcct ggaggaagct   1260

gagtatcggc gggagctggc cctgagaaat gagctcattc ggcaggagaa gctagagcaa   1320

ctggcccggc gctttgaccg gaaggccgca atgagagaga cctggctcag tgaaaaccag   1380

cgcctcgtgg cccaggataa ctttgggtat gacctggcag ctgtggaggc cgccaagaag   1440

aagcatgagg ccatcgagac cgacacggct gcctacgagg agcgggtgag agccctggag   1500

gacctggctc aggagctgga gaaagagaac taccatgacc agaagcgcat cacggcccgc   1560

aaggacaata tactgcgcct atggagctac ctgcaggagc tgctgcagtc ccggcgccag   1620

aggctcgaga ccaccctggc actgcagaag ctcttccagg acatgctgca cagcatcgac   1680

tggatggatg agatcaaggc tcacctcttg tctgccgagt ttgggaagca cttgttggag   1740

gttgaagacc tgctacagaa gcacaagttg atggaagctg acatcgccat ccaaggggac   1800

aaagtgaagg ccatcaccgc agccaccctg aagttcaccg aggggaaagg gtaccagcct   1860

tgtgaccccc aggtcatcca ggaccgcatc agccacttgg agcagtgctt tgaggagctg   1920

agcaacatgg cagctgggcg gaaggcccaa ctggagcagt ccaaacgact ctggaagttc   1980

ttctgggaga tggatgaggc tgagagctgg atcaaggaga aggagcagat ctattcttcc   2040

ctggactatg gcaaagacct gaccagtgtg ctcatcttac agcgcaagca caaggccttt   2100

gaggatgagc tccgtgggct ggatgctcac ctggagcaga tcttccagga ggctcatggc   2160

atggttgcgc gcaagcagtt tgggcacccg cagatcgagg cccgcataaa ggaggtgtcg   2220

gcacagtggg accagctgaa ggacctggct gccttctgca agaagaacct ccaggatgct   2280

gagaactttt tccagttcca gggcgatgcg gatgacctga aggcttggct gcaagacgcc   2340

caccggctgc tctctggtga agatgtgggg caggacgaag gggccacgcg ggccctgggg   2400

aaaaagcaca aggacttcct ggaggagctg gaggagagcc gtggggtgat ggagcacctg   2460

gagcagcagg cccagggatt ccccgaagag tttcgggatt ccccagatgt gacccatcgg   2520

ctgcaggccc tgcgggagct ctaccaacag gtggtggccc aggcggacct gcgtcagcag   2580

aggctgcagg aagccctgga cctgtacacg gtgttcgggg agacagacgc ctgtgagctg   2640

tggatgggag agaaggagaa gtggctggcc gagatggaaa tgccagacac cctggaggac   2700

ctggaggtcg tgcagcacag gttcgacatc ctggaccagg agatgaagac cttgatgact   2760

cagattgatg gtgtgaacct cgctgccaac agcttggtag agagtggcca cccacgcagc   2820

agggaggtga agcagtacca ggaccatctg aacaccaggt ggcaggcatt tcagaccctg   2880

gtgtcggagc ggcgggaggc tgtggactca gccctccgag tgcacaacta ctgcgtagat   2940

tgcgaggaga ccagcaagtg gatcacggac aagacaaagg tagtggagtc cacaaaagac   3000

ctggggcggg acctggcagg tatcatcgcc atccagagga agttgtcagg gctggagcgt   3060

gacgtggccg ccatccaggc ccgtgtggat gccctggagc gtgagtccca gcagctgatg   3120

gactcgcacc ctgagcagaa ggaggatatt ggtcagcggc aaaaacactt ggaggagctg   3180

tggcagggcc tgcagcaatc cctgcagggc caggaggact tgctggggga agtcagccag   3240

ctgcaggcct tcctgcagga tctggatgac ttccaggcct ggctctccat cacccagaag   3300

gctgtggcct ctgaggacat gcccgaatcc ctcccagagg ctgagcagct cctgcagcag   3360

catgcaggta tcaaggatga gattgacggg caccaagaca gctaccagcg tgttaaggag   3420

tctggggaga aagtgatcca aggccagacg gacccagagt atctgcttct gggccagcgg   3480

ctggagggcc tggatactgg ctggaatgcc ctgggcagga tgtgggagag ccgcagccac   3540

accctcgctc agtgccttgg cttccaggag ttccagaaag atgccaagca ggctgaagcc   3600

atcctcagca accaggaata cactctggct cacttggagc ccccagactc cctggaagct   3660

gcagaggctg ggatccggaa gtttgaggat ttcttggggt ctatggagaa caaccgggat   3720

aaggtcttga gtcctgtgga ctctggaaac aagctggtag ctgagggaaa cctatactca   3780

gacaagatca aggagaaggt gcagctgatt gaggacaggc acaggaagaa caacgagaag   3840

gcccaggagg cctctgtcct actgagagac aacctggagc tacagaactt cctccagaac   3900

tgccaggagc tcactctctg gatcaacgac aagctgctga catctcagga tgtctcctat   3960

gatgaagcac gaaaccttca caataaatgg ctaaagcacc aggcgtttgt ggcagagctg   4020

gcttcccatg aagggtggct agagaacatc gatgcggaag gaaagcagct gatggatgag   4080

aagccccagt ttacagccct ggtgtcccaa aagctggaag ccctgcaccg gctctgggac   4140

gagctgcagg ccaccacaaa ggagaagacc cagcacctct cggctgccag gagctccgac   4200

ctgcgcttgc agacccatgc tgacctcaac aagtggatca gcgccatgga ggaccagctg   4260

cggtcagacg acccgggcaa ggacctgacc agtgtcaatc ggatgttggc taagctgaag   4320

cgagtggagg accaagtgaa tgtgcgaaaa gaggagctgg gggagctgtt tgcccaggtg   4380

ccttcaatgg gagaggaggg aggagatgca gacttgagca tcgagaagcg gttcctggac   4440

ctcctggaac ccctaggaag gaggaagaag cagctggaat catccagagc caagctgcag   4500

atcagccggg acttagagga tgagacgctt tgggtggagg agaggctgcc tctggcccag   4560

tcagccgact atggcactaa tctgcaaact gtgcaactgt tcatgaagaa gaaccagaca   4620

ctgcagaatg agattctggg ccatacgccg cgggttgagg atgtgctgca gagagggcag   4680

cagctggtgg aggcggcgga gatcgactgc caggaccttg aggagcgcct ggggcacctg   4740

cagagctcct gggacaggct gcgggaggca gcggccggga ggctgcagcg actgagggac   4800

gccaacgagg cacagcagta ctacctggat gcagacgagg ctgaggcctg gattggcgag   4860

caggagctct acgtcatctc cgatgagatc cccaaggatg aagagggcgc cattgtgatg   4920

ctgaagcgac atttgcggca gcagcgtgcg gtggaggact acggccggaa catcaagcag   4980

ctggccagcc gggcccaggg cctgctgtct gcaggccacc ctgaggggga acagatcatc   5040

agacttcagg ggcaagtgga caagcactac gcagggctga aggacgtggc ggaagagcgc   5100

aagcgcaagc tggagaacat gtaccacctg ttccagctca agcgggagac cgacgacctg   5160

gagcagtgga tttcagaaaa ggagctagtg gcctcttccc cggaaatggg gcaagacttt   5220

gaccacgtga ctcttctgcg ggacaagttc cgggactttg cccgggagac cggggcgatt   5280

gggcaggagc gggtggacaa tgtgaatgcc ttcatcgagc gactcatcga cgcgggccac   5340

agcgaggcgg ccaccatcgc cgagtggaag gacgggctga acgagatgtg ggcagacctc   5400

ctggagctca ttgacacgcg catgcagctg ctggccgcct cctatgacct gcaccgctac   5460

ttctacacgg gtgccgagat cctgggcctc atcgacgaga agcaccgcga gctgcccgag   5520

gacgtggggc tggacgccag cacggccgag tccttccacc gggtgcacac agccttcgag   5580

cgggagctcc acctgctggg tgtccaggtg cagcagttcc aggacgtggc cacccgtctg   5640

cagacagcat atgctgggga gaaggcagag gccatccaga acaaggagca ggaggtgtct   5700

gccgcgtggc aggcgctgct cgatgcctgt gccgggcgcc ggacccagct agtggacacg   5760

gcggataaat tccgcttctt cagcatggcc cgtgacctcc tctcctggat ggagagcatc   5820

atccggcaga tcgagaccca ggagaggccc agggatgtct cctctgtgga actgctcatg   5880

aagtatcacc agggcatcaa tgcagagatt gaaacccgga gcaagaactt cagtgcctgc   5940

ctggagcttg gcgagtccct gctgcagcgg cagcaccagg cctcagagga gatccgcgag   6000

aaactgcagc aggtgatgtc caggaggaaa gagatgaatg agaagtggga agcccgctgg   6060

gagcggctcc gcatgttgct ggaggtgtgc cagttctcga gggatgcctc tgtggctgag   6120

gcgtggctga ttgcccagga gccctacctg gccagcgggg actttggaca cacagtggac   6180

agtgtggaga agctcatcaa gaggcatgag gcttttgaga agtccacggc cagctgggca   6240

gagcgctttg ctgccctgga gaagcccacc acgcttgagc tgaaagaacg ccagattgca   6300

gagagacccg cagaggagac tgggcctcaa gaggaggaag gcgagacagc aggggaggct   6360

ccagtttccc accatgcggc caccgagaga acgtccccgg gggaagaaga gggaacgtgg   6420

cctcagaacc tgcagcagcc accaccgccg ggtcagcaca aggatgggca gaaatccact   6480

ggggatgaga ggcccaccac ggagcccctc tttaaggtcc tagatacgcc tctgagcgag   6540

ggtgatgagc ccgcaacgct gccggccccg cgggaccatg ggcagagtgt gcagatggaa   6600

ggctacctgg gccgcaagca tgacctggag gggcccaaca agaaggcttc caacaggtcc   6660

tggaacaacc tgtactgtgt gctcaggaac agtgagctaa ccttctacaa ggatgccaag   6720

aacctggccc tggggatgcc ctaccatggg gaggaacccc tggccctgag acatgccatc   6780

tgtgagattg ctgccaacta caagaagaag aagcacgtct ttaagctgag gctgagtaat   6840

ggcagcgagt ggctcttcca tggcaaggat gaggaggaga tgctgtcctg gctgcagggc   6900

gtgagcaccg ccatcaacga gtcccagagc atccgcgtca aggcgcagag cctgcccctg   6960

ccttccctct ccggccccga cgccagcctc ggcaagaaag acaaggagaa gagattcagc   7020

ttcttcccca aaaagaagta gcaggtgggg ctggcgggcg cggcggagtc gggacgcgca   7080

gagaccgggc agcccaggcc ttggcctcct ctcgccgccg cccgccggtc gaatcgagat   7140

gagtcgagtc gcgggccggg cccccgggcc ccacgctgca ctgcaaaagc tgccttcgcc   7200

cgcgtgtcct gggccgacgc cccctccatg ccctcgcccg cgctggctcc gctccaggga   7260

caggggctcc cagctcctct ggcgcctttg gggcctccag gcctgggggc aggaaacggt   7320

tctctgaggc acacgccctc ctctcccacc ctcctcctga gccgaggggg cacaggcccc   7380

ttacccccaa ccaaaaaaaa aaaaaaaaaa gagctggaga aggctgatgg ggttcttcaa   7440

acgctgcccg ttcctaaagc aagtcttgct tcgggtcacc tcccacctgg tggcagccag   7500

ggaaagggga aaggaagaag acactggaaa tgcatggcca gccccctagg ggcatgagga   7560

aggagccttc aggtggccca caaagcccta gctctgggcc aggggctctg gggggctgag   7620

gggaccagac tgggtgcagg gccttgggag ctgccagcct ccttcccact gggcttccgc   7680

agaactggga ctctcacttc aggggccacc acatccctcc tctctgcttc tccccccaga   7740

tcaaagggta ccctcccacg gttggcaggg cctggctgag tgcctctagc accctttgtg   7800

ccaccacagg cggtcccagg aagggcagca aggtcagacc attcctcatt gaaaaccgtg   7860

gctagggcac agggctctga tctgaaggag tgacaggtgc gtcacaacac tgcctaaggc   7920

tctccctctc aatgctggga ccctcgcccc actcccagtg gcagccaaac cagcaatatc   7980

caacagacat aggcccccta cgggacagtg tgggccccca gatataagat ggataccccc   8040

cgcacctgca gtaaagcatc ccaaagccaa atgctcaatt gcatcctgtc tgcagctggg   8100

actttggagg gtaatggctg ggcagacagt aaagttgatc atctgttttc tcggggtggc   8160

agacgcagcc atgtcttggt atcaccaccc atgtgacagc tactcctgca caactgggac   8220

aaatgtcagg gccagagcca tgaaggtgtg gtaccccttg atcagcttct ccacgtcctg   8280

gccccaggtc ttggcgggga gggggtcaca tgagtacaga ggtcaaatat ctaccaccct   8340

ccagccctga gcaccagaag ctctgcaacc aacgtcccca ggaatggcct tccccttgct   8400

gctcaggtca tacttctgga ggaagagaaa gctcattcca tattttcccc accactctac   8460

tccgaaagca acacagttct ggcccagtat caaactaggg ttaggtccaa gagagcagtc   8520

aagcgggtcg ggggtggggg ggagggcgga gggcagcagg cattttcccc caaggaaacc   8580

atgaaagtcc ccagggcctg cagtcaagtt tctatcacct tccccgtgag aaggacctta   8640

gttccatgga gatgaagtgg gtgaggttca ggtagaagcc acaggggcag gcatccagaa   8700

tgaggccccc tgaggaaccc tgagtgctga ccagtgccgg cagaaatcag ttccaccctg   8760

tggccctgac actatatgtc agggtgacac caactgcagc aggcaggagc cacaggaagg   8820

aagacgtcat ccgatggagc ctgacatccc caggttcccg ccctggtgag caaggtcttc   8880

atttggcttt ggtacatatg accctataca gggaacctag tgtgtatcac tcaccagcct   8940

ctttctgtat ctggggaaac caaggcagtg aggtgactgc actcacctag caataaagta   9000

ggcctttggt gcacttgcag gcatgtcctc ctctggggca gagagcaggt tccttgctga   9060

agggcagatg gtggcaaaca tctccctcaa ctgtttccct gggccagtct ttagggagcc   9120

tagggacaag ggcccaccct cccccttcca cgtgtgccaa atcagcacct gaagtgaggc   9180

atttccagca agcaactcca cagacccgag aaaggaaggg ctctagtgga agagctagca   9240

tctcaccacc ccaggtcccc tggcctggtc cagggcagcc agctgcatgt gaccattctg   9300

ttgccagctc cccacacatc cctcctgtca cccaggctcc aagacattcg accaactaga   9360

ctgaaaatgc aggcatccag ctttgggaga ccctgtgtgt gccacaccag ggctaagctc   9420

tcccagtgcc ctagcaaggt cttttttttt ttttctctcc ttattctact ctacagtctt   9480

ttgacagtat tcccaaacga ggttgacaca gctccagtcc acaccagcat accaggcttc   9540

cttcccaggg cagtttagag gaagctcctt ctgggcaagg tcaggcggtc ctccttccct   9600

ctctccttcc cctttgtccc agcctcaact gactctggct gtgggaggtg tggagggtcc   9660

ttaggcttcc ctccccaacc tggcctccac caacacccct aacaggaggc ccgtggaagg   9720

ctcagcctct cctccgcatc cctcctcctt cctgcctatc ggagggagcc agggtcccct   9780

aggctgaccc tgaatcctct tcctcccttc atgggagggg ggcaggaatc cagaggagga   9840

tgaagccagc gggaccacat ggcttggtgg cttggacaaa caagctcagg gaggaaatga   9900

ggaggcggcg gctgcagagg aatgcaaccc tgttgggcac agaccatgca atctggggct   9960

ggccctgggg ccagctgggt cctgtcctcc acctgctcaa ccgtgcttcc accaaccaga  10020

ggaaacccat ttactagttt ttctaataaa tcaataatgc tccaaaaaaa aaaa        10074


<210>  546
<211>  1719
<212>  DNA
<213>  Human

<400>  546
gctccacctc gtccgtggcc ctgcccaccc aggccgcaag agctgccggg acggtcccca     60

tcttcttgga gcgctttagg ctggccggcg gcgctgggag gtggagtcgt tgctgttgct    120

gtttgtgagc ctgtggcgcg gcttctgtgg gccggaacct taaagatagc cgcaatggct    180

gaaaatggtg ataatgaaaa gatggctgcc ctggaggcca aaatctgtca tcaaattgag    240

tattattttg gcgacttcaa tttgccacgg gacaagtttc taaaggaaca gataaaactg    300

gatgaaggct gggtaccttt ggagataatg ataaaattca acaggttgaa ccgtctaaca    360

acagacttta atgtaattgt ggaagcattg agcaaatcca aggcagaact catggaaatc    420

agtgaagata aaactaaaat cagaaggtct ccaagcaaac ccctacctga agtgactgat    480

gagtataaaa atgatgtaaa aaacagatct gtttatatta aaggcttccc aactgatgca    540

actcttgatg acataaaaga atggttagaa gataaaggtc aagtactaaa tattcagatg    600

agaagaacat tgcataaagc atttaaggga tcaatttttg ttgtgtttga tagcattgaa    660

tctgctaaga aatttgtaga gacccctggc cagaagtaca aagaaacaga cctgctaata    720

cttttcaagg acgattactt tgccaaaaaa aatgaagaaa gaaaacaaaa taaagtggaa    780

gctaaattaa gagctaaaca ggagcaagaa gcaaaacaaa agttagaaga agatgctgaa    840

atgaaatctc tagaagaaaa gattggatgc ttgctgaaat tttcgggtga tttagatgat    900

cagacctgta gagaagattt acacatactt ttctcaaatc atggtgaaat aaaatggata    960

gacttcgtca gaggagcaaa agaggggata attctattta aagaaaaagc caaggaagca   1020

ttgggtaaag ccaaagatgc aaataatggt aacctacaat taaggaacaa agaagtgact   1080

tgggaagtac tagaaggaga ggtggaaaaa gaagcactga agaaaataat agaagaccaa   1140

caagaatccc taaacaaatg gaagtcaaaa ggtcgtagat ttaaaggaaa aggaaagggt   1200

aataaagctg cccagcctgg gtctggtaaa ggaaaagtac agtttcaggg caagaaaacg   1260

aaatttgcta gtgatgatga acatgatgaa catgatgaaa atggtgcaac tggacctgtg   1320

aaaagagcaa gagaagaaac agacaaagaa gaacctgcat ccaaacaaca gaaaacagaa   1380

aatggtgctg gagaccagta gtttagtaaa ccaatttttt attcatttta aataggtttt   1440

aaacgacttt tgtttgcggg gcttttaaaa ggaaaaccga attaggtcca cttcaatgtc   1500

cacctgtgag aaaggaaaaa tttttttgtt gtttaacttg tctttttgtt atgcaaatga   1560

gatttctttg aatgtattgt tctgtttgtg ttatttcaga tgattcaaat atcaaaagga   1620

agattcttcc attaaattgc ctttgtaata tgagaatgta ttagtacaaa ctaactaata   1680

aaatatatac tatatgaaaa gagcaaaaaa aaaaaaaaa                          1719


<210>  547
<211>  4186
<212>  DNA
<213>  Human

<400>  547
gttcttgggg cgtgggcgaa gcaggctgct cgcctcctgc ctgtagtgtg tgggctgggg     60

ttggtgcgag cttccagctt ggccgcagtt ggttcgtagt tcggctctgg ggtcttttgt    120

gtccgggtct ggcttggctt tgtgtccgcg agtttttgtt ccgctccgca gcgctcttcc    180

cgggcaggag ccgtgaggct cggaggcggc agcgcggtcc ccggccagga gcaagcgcgc    240

cggcgtgagc ggcggcggca aaggctgtgg ggagggggct tcgcagatcc ccgagatgcc    300

ggagttcctg gaagacccct cggtcctgac aaaagacaag ttgaagagtg agttggtcgc    360

caacaatgtg acgctgccgg ccggggagca gcgcaaagac gtgtacgtcc agctctacct    420

gcagcacctc acggctcgca accggccgcc gctccccgcc ggcaccaaca gcaaggggcc    480

cccggacttc tccagtgacg aagagcgcga gcccaccccg gtcctcggct ctggggccgc    540

cgccgcgggc cggagccgag cagccgtcgg caggaaagcc acaaaaaaaa ctgataaacc    600

cagacaagaa gataaagatg atctagatgt aacagagctc actaatgaag atcttttgga    660

tcagcttgtg aaatacggag tgaatcctgg tcctattgtg ggaacaacca ggaagctata    720

tgagaaaaag cttttgaaac tgagggaaca aggaacagaa tcaagatctt ctactcctct    780

gccaacaatt tcttcttcag cagaaaatac aaggcagaat ggaagtaatg attctgacag    840

atacagtgac aatgaagaag actctaaaat agagctcaag cttgagaaga gagaaccact    900

aaagggcaga gcaaagactc cagtaacact caagcaaaga agagttgagc acaatcagag    960

ctattctcaa gctggaataa ctgagactga atggacaagt ggatcttcaa aaggcggacc   1020

tctgcaggca ttaactaggg aatctacaag agggtcaaga agaactccaa ggaaaagggt   1080

ggaaacttca gaacattttc gtatagatgg tccagtaatt tcagagagta ctcccatagc   1140

tgaaactata atggcttcaa gcaacgaatc cttagttgtc aatagggtga ctggaaattt   1200

caagcatgca tctcctattc tgccaatcac tgaattctca gacataccca gaagagcacc   1260

aaagaaacca ttgacaagag ctgaagtggg agaaaaaaca gaggaaagaa gagtagaaag   1320

ggatattctt aaggaaatgt tcccctatga agcatctaca ccaacaggaa ttagtgctag   1380

ttgccgcaga ccaatcaaag gggctgcagg ccggccatta gaactcagtg atttcaggat   1440

ggaggagtct ttttcatcta aatatgttcc taagtatgtt cccttggcag atgtcaagtc   1500

agaaaagaca aaaaagggac gctccattcc cgtatggata aaaattttgc tgtttgttgt   1560

tgtggcagtt tttttgtttt tggtctatca agctatggaa accaaccaag taaatccctt   1620

ctctaatttt cttcatgttg accctagaaa atccaactga atggtatctc tttggcacgt   1680

tcaacttggt ctcctatttt caataactgt tgaaaaacat ttgtgtacac ttgttgactc   1740

caagaactaa aaataatgtg atttcgcctc aataaatgta gtatttcatt gaaaagcaaa   1800

caaaatatat ataaatggac ttcattaaaa tgtttttgaa ctttggacta gtaggagatc   1860

actttgtgcc atatgaataa tcttttttag ctctggaact ttttgtaggc tttatttttt   1920

taatgtgggc atcttatttc atttttgaaa aaatgtatat gttttttgtg tatttgggaa   1980

acgaagggtg aaacatggta gtataatgtg aagctacaca tttaaatact tagaattctt   2040

acagaaaaga ttttaagaat tattctctgc tgaataaaaa ctgcaaatat gtgaaacata   2100

atgaaattca gtaagaggaa aagtaacttg gttgtacttt ttgtaactgc aacaaagttt   2160

gatggtgttt atgaggaaaa gtacagcaat aatctcttct gtaaccttta ttaatagtaa   2220

tgttgttgta gccctatcat actcactttt taagacacag tatcatgaaa gtcctatttc   2280

agtaagaccc atttacatac agtagatttt tagcagagat cttttagtgt aacatacata   2340

ttttagagaa ttgttggcta gctgtacatg ttttgaaaag ctgtttagct agctataagg   2400

ctataattgg aaatttgtat tttttattta cagcaaaaca tttattcagt catccagttt   2460

gctaccaaaa tatgttttag ataagtgtgt gtatgtttgt ttagaagtta gaaattgtaa   2520

acactggtct tatgtttcat ttggattcat tattgcattg tcttgttacc agaaacaaat   2580

tttgccgagc tttttttgcc ctatatttcc cagcataatt tgattagaaa gtacaaaaag   2640

ggccaggcgc ggtggcttac gcctgtaatc ccagcacttt gggaggccag ggcgggtgga   2700

tcacgaggtc aagagatcaa gaccatcctg gccaacatgg tgaaaccccg tctctactaa   2760

aaatacaaaa aaattagctg ggcgtgatga tgtgcgcctg tagtcctgtc tactagggag   2820

actgaggcag gagaatcgtt tgaacccagg aggcagaggt tgcagtgagc agagattacg   2880

tcactgcact gtagcctggc gacagagcaa gactccatct caaaaaaaat aaaaaagtac   2940

aaaaagtact tgcttttata ttacatcata agcagtagtt aataaagttg tatactctta   3000

agaggtgggc attatgatta ttttttattt ttttattttt tatgagatgg agtctcactc   3060

ttgtcaccca gactgtagtg cagtggcacg atctgggctc gatgcaacct ctgcctccca   3120

ggttcaagca attttcctgc ctcggcagag acggggtttc accatgttgg ccaggctggt   3180

ctcgaacccc tgacctcaag tgatcagccc acctcagctt cccaaagtgc tgggattaca   3240

ggtgtgatcc actgcacccg gccggcatta tgattttgtg tactcttgaa atggttatct   3300

ttgtggatga tttttttttt taagctgaaa cttacctcat gaataacttg attaaagtag   3360

taggtgatta aaatttcaat agaatcaaat gagacaaaaa ttttaaactg actcatttga   3420

gtttcaactt tacagtcatt gaccataaag cacactaaaa atgtaagtta tttttaaata   3480

catctgaaat aaaaatactt actaaaaagg aagaagccga agatgtatat ttagaccagc   3540

acacaatttt gatttcaatt agccttattc taatatttag cttttagatc tttcatacac   3600

attttcacgt actttgcaat tgagaccaga aagacttgta ggtctttctg cagaatgagt   3660

gggtccttgc aaagtgagtg ggaaacttac tcctagatca gaaatgtttg cctctctgag   3720

taaaatgttt ctttcagatg agccatagag ggggcacctt ttactcaact tttctttgtt   3780

ttgaaacttt gtttcccata ctgttttcag ccttttgttt ataattagaa attgtgagaa   3840

gcttcattta gtgtttaaaa atgtggggag ataaatcaga cttaacatgt atgtaagatc   3900

aattcactta aaagtatggt ccaaatagca aaaataggac caggtgaaac atgtagtcat   3960

tttttaaaaa catgtacttg gtcttttgtg tgtgtctgtt ttattccatt agaataaatg   4020

tgtccttgat gtaaatgcaa agcatttctt cctgattaaa ttgtagatgt agactttaca   4080

atataattca ataataaaaa gtaattaacc tctagttttg tcgttgcaat aaatggtttt   4140

cagatagcac aaactgtgat ttctggataa catttcttat gaaaaa                  4186


<210>  548
<211>  1946
<212>  DNA
<213>  Human

<400>  548
gcttctgagc ggaaactgaa agtgaaatag ggagctggct accagcgttg agtcccctgt     60

aaagccaaac cccctaaagg tctccacact gctgtttaac ggcacacttg acaatggctt    120

cagcagcacg cttgacaatg atgtgggagg aggtcacatg ccctatctgc ctggacccct    180

tcgtggagcc tgtgagcatc gagtgtggcc acagcttctg ccaggaatgc atctctcagg    240

ttgggaaagg tgggggcagc gtctgtcctg tgtgccggca gcgctttctg ctcaagaatc    300

tccggcccaa tcgacagcta gccaacatgg tgaacaacct taaagaaatc agccaggagg    360

ccagagaggg cacacagggg gaacggtgtg cagtgcatgg agagagactt cacctgttct    420

gtgagaaaga tgggaaggcc ctttgctggg tatgtgccca gtctcggaaa caccgtgacc    480

acgccatggt ccctcttgag gaggctgcac aggagtacca ggagaagctc caggtggcat    540

taggggaact gagaagaaag caggagttgg ctgagaagtt ggaagtggaa attgcaataa    600

agagagcaga ctggaagaaa acagtggaaa cacagaaatc taggattcac gcagagtttg    660

tgcagcaaaa aaacttcctg gttgaagaag aacagaggca gctgcaggag ctggagaagg    720

atgagaggga gcagctgaga atcctggggg agaaagaggc caagctggcc cagcagagcc    780

aggccctaca ggagctcatc tcagagctag atcgaaggtg ccacagctca gcactggaac    840

tgctgcagga ggtgataatt gtcctggaaa ggagtgagtc ctggaacctg aaggacctgg    900

atattacctc tccagaactc aggagtgtgt gccatgtgcc agggctgaag aagatgctga    960

ggacatgtgc agtccacatc actctggatc cagacacagc caatccgtgg ctgatacttt   1020

cagaagatcg gagacaagtg aggcttggag acacccagca gagcatacct ggaaatgaag   1080

agagatttga tagttatcct atggtcctgg gtgcccagca ctttcactct ggaaaacatt   1140

actgggaggt agatgtgaca ggaaaggagg cctgggacct gggtgtctgc agagactctg   1200

tgcgcaggaa ggggcacttt ttgcttagtt ccaagagtgg cttctggaca atttggttgt   1260

ggaacaaaca aaaatatgag gctggcacct acccccagac tcccctccac cttcaggtgc   1320

ctccatgcca agttgggatt ttcctggact atgaggctgg catggtctcc ttctacaaca   1380

tcactgacca tggctccctc atctactcct tctctgaatg tgcctttaca ggacctctgc   1440

ggcccttctt cagtcctggt ttcaatgatg gaggaaaaaa cacagcccct ctaaccctct   1500

gtccactgaa tattggatca caaggatcca ctgactattg atggctttct ctggacactg   1560

ccactctccc cattggcacc gcttctcagc cacaaaccct gcctcttttc cccatgaact   1620

ctgaaccacc tttgtctctg cagaggcatc cggatcccag caagcgagct ttagcaggga   1680

agtcacttca ccatcaacat tcctgcccca gatggctttg tgattccctc cagtgaagca   1740

gcctccttat atttggccca aactcatctt gatcaaccaa aaacatgttt ctgccttctt   1800

tatgggactt aagttttttt tttctcctct ccatctctag gatgtcgtct ttggtgagat   1860

ctctattata tcttgtatgg tttgcaaaag ggcttcctaa aaataaaaaa taaaatttaa   1920

aaaactgtga aaaaaaaaaa aaaaaa                                        1946


<210>  549
<211>  2050
<212>  DNA
<213>  Human

<400>  549
gggttgaggc tgggcaaacg ccgcgaaact atcgctcttc cccgtcccgc ttccgcgcct     60

gtccaccctg ggtaacggaa ccagcatcgc ggtagggaca tcctcgctag gcccggccgg    120

accattcctc agggtgggcc ctttccgaag ccgggaccgc tcctgcttgt cggcatcgct    180

ccccacaggc cgacgtcgag agggcctgct ttactcctcc tctttctcct ccttctcccg    240

cggcttctgc gcggagaggc gtcgcccggg atctgggttt tggaagaagg atctttgtgg    300

gaagacaggg tgaatttatc acagaggaat aacgagggag aggagaaagg tttcctaaag    360

acaaaaaaaa atggaggaat ctgtaaacca aatgcagcca ctgaatgaga agcagatagc    420

caattctcag gatggatatg tatggcaagt cactgacatg aatcgactac accggttctt    480

atgtttcggt tctgaaggtg ggacttatta tatcaaagaa cagaagttgg gccttgaaaa    540

tgctgaagct ttaattagat tgattgaaga tggcagagga tgtgaagtga tacaagaaat    600

aaagtcattt agtcaagaag gcagaaccac aaagcaagag cctatgctct ttgcacttgc    660

catttgttcc cagtgctccg acataagcac aaaacaagca gcatttaaag ctgtttctga    720

agtttgtcgc attcctaccc atctctttac ttttatccag tttaagaaag atctgaagga    780

aagcatgaaa tgtggcatgt ggggtcgtgc cctccggaag gctatagcgg actggtacaa    840

tgagaaaggt ggcatggccc ttgctctggc agttacaaaa tataaacaga gaaatggctg    900

gtctcacaaa gatctattaa gattgtcaca tcttaaacct tccagtgaag gacttgcaat    960

tgtgaccaaa tatattacaa agggctggaa agaagttcat gaattgtata aagaaaaagc   1020

actctctgtg gagactgaaa aattattaaa gtatctggag gctgtagaga aagtgaagcg   1080

cacaagagat gagctagaag tcattcatct aatagaagaa catagattag ttagagaaca   1140

tcttttaaca aatcacttaa agtctaaaga ggtatggaag gctttgttac aagaaatgcc   1200

gcttactgca ttactaagga atctaggaaa gatgactgct aattcagtac ttgaaccagg   1260

aaattcagaa gtatctttag tatgtgaaaa actgtgtaat gaaaaactat taaaaaaggc   1320

tcgtatacat ccatttcata ttttgatcgc attagaaact tacaagacag gtcatggtct   1380

cagagggaaa ctgaagtggc gccctgatga agaaattttg aaagcattgg atgctgcttt   1440

ttataaaaca tttaagacag ttgaaccaac tggaaaacgt ttcttactag ctgttgatgt   1500

cagtgcttct atgaaccaaa gagttttggg tagtatactc aacgctagta cagttgctgc   1560

agcaatgtgc atggttgtca cacgaacaga aaaagattct tatgtagttg ctttttccga   1620

tgaaatggta ccatgtccag tgactacaga tatgacctta caacaggttt taatggctat   1680

gagtcagatc ccagcaggtg gaactgattg ctctcttcca atgatctggg ctcagaagac   1740

aaacacacct gctgatgtct tcattgtatt cactgataat gagacctttg ctggaggtgt   1800

ccatcctgct attgctctga gggagtatcg aaagaaaatg gatattccag ctaaattgat   1860

tgtttgtgga atgacatcaa atggtttcac cattgcagac ccagatgata gagccttgca   1920

aaatacccta ctaaataaat cattttagac atggagtgca ggtggacact gtgtgaactg   1980

tttttggtca gttattgtag aaattgatag atgtaccaaa taaactctat gcacattaaa   2040

aaaaaaaaaa                                                          2050


<210>  550
<211>  2151
<212>  DNA
<213>  Human

<400>  550
gcctctccaa aggctgcaga agtttcttgc taacaaaaag tccgcacatt cgagcaaaga     60

caggctttag cgagttatta aaaacttagg ggcgctcttg tcccccacag ggcccgaccg    120

cacacagcaa ggcgatggcc cagctgtaag ttggtagcac tgagaactag cagcgcgcgc    180

ggagcccgct gagacttgaa tcaatctggt ctaacggttt cccctaaacc gctaggagcc    240

ctcaatcggc gggacagcag ggcgcgtcct ctgccactct cgctccgagg tccccgcgcc    300

agagacgcag ccgcgctccc accacccaca cccaccgcgc cctcgttcgc ctcttctccg    360

ggagccagtc cgcgccaccg ccgccgccca ggccatcgcc accctccgca gccatgtcca    420

ccaggtccgt gtcctcgtcc tcctaccgca ggatgttcgg cggcccgggc accgcgagcc    480

ggccgagctc cagccggagc tacgtgacta cgtccacccg cacctacagc ctgggcagcg    540

cgctgcgccc cagcaccagc cgcagcctct acgcctcgtc cccgggcggc gtgtatgcca    600

cgcgctcctc tgccgtgcgc ctgcggagca gcgtgcccgg ggtgcggctc ctgcaggact    660

cggtggactt ctcgctggcc gacgccatca acaccgagtt caagaacacc cgcaccaacg    720

agaaggtgga gctgcaggag ctgaatgacc gcttcgccaa ctacatcgac aaggtgcgct    780

tcctggagca gcagaataag atcctgctgg ccgagctcga gcagctcaag ggccaaggca    840

agtcgcgcct gggggacctc tacgaggagg agatgcggga gctgcgccgg caggtggacc    900

agctaaccaa cgacaaagcc cgcgtcgagg tggagcgcga caacctggcc gaggacatca    960

tgcgcctccg ggagaaattg caggaggaga tgcttcagag agaggaagcc gaaaacaccc   1020

tgcaatcttt cagacaggat gttgacaatg cgtctctggc acgtcttgac cttgaacgca   1080

aagtggaatc tttgcaagaa gagattgcct ttttgaagaa actccacgaa gaggaaatcc   1140

aggagctgca ggctcagatt caggaacagc atgtccaaat cgatgtggat gtttccaagc   1200

ctgacctcac ggctgccctg cgtgacgtac gtcagcaata tgaaagtgtg gctgccaaga   1260

acctgcagga ggcagaagaa tggtacaaat ccaagtttgc tgacctctct gaggctgcca   1320

accggaacaa tgacgccctg cgccaggcaa agcaggagtc cactgagtac cggagacagg   1380

tgcagtccct cacctgtgaa gtggatgccc ttaaaggaac caatgagtcc ctggaacgcc   1440

agatgcgtga aatggaagag aactttgccg ttgaagctgc taactaccaa gacactattg   1500

gccgcctgca ggatgagatt cagaatatga aggaggaaat ggctcgtcac cttcgtgaat   1560

accaagacct gctcaatgtt aagatggccc ttgacattga gattgccacc tacaggaagc   1620

tgctggaagg cgaggagagc aggatttctc tgcctcttcc aaacttttcc tccctgaacc   1680

tgagggaaac taatctggat tcactccctc tggttgatac ccactcaaaa aggacacttc   1740

tgattaagac ggttgaaact agagatggac aggttatcaa cgaaacttct cagcatcacg   1800

atgaccttga ataaaaattg cacacactca gtgcagcaat atattaccag caagaataaa   1860

aaagaaatcc atatcttaaa gaaacagctt tcaagtgcct ttctgcagtt tttcaggagc   1920

gcaagataga tttggaatag gaataagctc tagttcttaa caaccgacac tcctacaaga   1980

tttagaaaaa agtttacaac ataatctagt ttacagaaaa atcttgtgct agaatacttt   2040

ttaaaaggta ttttgaatac cattaaaact gctttttttt ttccagcaag tatccaacca   2100

acttggttct gcttcaataa atctttggaa aaactcaaaa aaaaaaaaaa a            2151


<210>  551
<211>  3448
<212>  DNA
<213>  Human

<400>  551
acggtttccc cgcccctttc aggcctagca ggaaacgaag cggctctttc cgctatctgc     60

cgcttgtcca ccggaagcga gttgcgacac ggcaggttcc cgcccggaag aagcgaccaa    120

agcgcctgag gaccggcaac atggtgcggt cggggaataa ggcagctgtt gtgctgtgta    180

tggacgtggg ctttaccatg agtaactcca ttcctggtat agaatcccca tttgaacaag    240

caaagaaggt gataaccatg tttgtacagc gacaggtgtt tgctgagaac aaggatgaga    300

ttgctttagt cctgtttggt acagatggca ctgacaatcc cctttctggt ggggatcagt    360

atcagaacat cacagtgcac agacatctga tgctaccaga ttttgatttg ctggaggaca    420

ttgaaagcaa aatccaacca ggttctcaac aggctgactt cctggatgca ctaatcgtga    480

gcatggatgt gattcaacat gaaacaatag gaaagaagtt tgagaagagg catattgaaa    540

tattcactga cctcagcagc cgattcagca aaagtcagct ggatattata attcatagct    600

tgaagaaatg tgacatctcc ctgcaattct tcttgccttt ctcacttggc aaggaagatg    660

gaagtgggga cagaggagat ggcccctttc gcttaggtgg ccatgggcct tcctttccac    720

taaaaggaat taccgaacag caaaaagaag gtcttgagat agtgaaaatg gtgatgatat    780

ctttagaagg tgaagatggg ttggatgaaa tttattcatt cagtgagagt ctgagaaaac    840

tgtgcgtctt caagaaaatt gagaggcatt ccattcactg gccctgccga ctgaccattg    900

gctccaattt gtctataagg attgcagcct ataaatcgat tctacaggag agagttaaaa    960

agacttggac agttgtggat gcaaaaaccc taaaaaaaga agatatacaa aaagaaacag   1020

tttattgctt aaatgatgat gatgaaactg aagttttaaa agaggatatt attcaagggt   1080

tccgctatgg aagtgatata gttcctttct ctaaagtgga tgaggaacaa atgaaatata   1140

aatcggaggg gaagtgcttc tctgttttgg gattttgtaa atcttctcag gttcagagaa   1200

gattcttcat gggaaatcaa gttctaaagg tctttgcagc aagagatgat gaggcagctg   1260

cagttgcact ttcctccctg attcatgctt tggatgactt agacatggtg gccatagttc   1320

gatatgctta tgacaaaaga gctaatcctc aagtcggcgt ggcttttcct catatcaagc   1380

ataactatga gtgtttagtg tatgtgcagc tgcctttcat ggaagacttg cggcaataca   1440

tgttttcatc cttgaaaaac agtaagaaat atgctcccac cgaggcacag ttgaatgctg   1500

ttgatgcttt gattgactcc atgagcttgg caaagaaaga tgagaagaca gacacccttg   1560

aagacttgtt tccaaccacc aaaatcccaa atcctcgatt tcagagatta tttcagtgtc   1620

tgctgcacag agctttacat ccccgggagc ctctaccccc aattcagcag catatttgga   1680

atatgctgaa tcctcccgct gaggtgacaa caaaaagtca gattcctctc tctaaaataa   1740

agaccctttt tcctctgatt gaagccaaga aaaaggatca agtgactgct caggaaattt   1800

tccaagacaa ccatgaagat ggacctacag ctaaaaaatt aaagactgag caagggggag   1860

cccacttcag cgtctccagt ctggctgaag gcagtgtcac ctctgttgga agtgtgaatc   1920

ctgctgaaaa cttccgtgtt ctagtgaaac agaagaaggc cagctttgag gaagcgagta   1980

accagctcat aaatcacatc gaacagtttt tggatactaa tgaaacaccg tattttatga   2040

agagcataga ctgcatccga gccttccggg aagaagccat taagttttca gaagagcagc   2100

gctttaacaa cttcctgaaa gcccttcaag agaaagtgga aattaaacaa ttaaatcatt   2160

tctgggaaat tgttgtccag gatggaatta ctctgatcac caaagaggaa gcctctggaa   2220

gttctgtcac agctgaggaa gccaaaaagt ttctggcccc caaagacaaa ccaagtggag   2280

acacagcagc tgtatttgaa gaaggtggtg atgtggacga tttattggac atgatatagg   2340

tcgtggatgt atggggaatc taagagagct gccatcgctg tgatgctggg agttctaaca   2400

aaacaagttg gatgcggcca ttcaagggga gccaaaatct caagaaattc ccagcaggtt   2460

acctggaggc ggatcatcta attctctgtg gaatgaatac acacatatat attacaaggg   2520

ataatttaga ccccatacaa gtttataaag agtcattgtt attttctggt tggtgtatta   2580

ttttttctgt ggtcttactg atctttgtat attacataca tgctttgaag tttctggaaa   2640

gtagatcttt tcttgaccta gtatatcagt gacagttgca gcccttgtga tgtgattagt   2700

gtctcatgtg gaaccatggc atggttattg atgagtttct taaccctttc cagagtcctc   2760

ctttgcctga tcctccaaca gctgtcacaa cttgtgttga gcaagcagta gcatttgctt   2820

cctcccaaca agcagctggg ttaggaaaac catgggtaag gacggactca cttctctttt   2880

tagttgaggc cttctagtta ccacattact ctgcctctgt atataggtgg ttttctttaa   2940

gtggggtggg aaggggagca caatttccct tcatactcct tttaagcagt gagttatggt   3000

ggtggtctca tgaagaaaag accttttggc ccaatctctg ccatatcagt gaacctttag   3060

aaactcaaaa actgagaaat ttactacagt agttagaatt atatcacttc actgttctct   3120

acttgcaagc ctcaaagaga gaaagtttcg ttatattaaa acacttaggt aacttttcgg   3180

tctttcccat ttctacctaa gtcagctttc atctttgtgg atggtgtctc ctttactaaa   3240

taagaaaata acaaagccct tattctcttt ttttcttgtc ctcattcttg ccttgagttc   3300

cagttcctct ttggtgtaca gacttcttgg tacccagtca cctctgtctt cagcaccctc   3360

ataagtcgtc actaatacac agttttgtac atgtaacatt aaaggcataa atgactcatc   3420

tctctgtgaa aaaaaaaaaa aaaaaaaa                                      3448


<210>  552
<211>  5653
<212>  DNA
<213>  Human

<400>  552
gacaaagaga actaatgctt tgtgctgatt catatttgaa tcgaggcatt gggaaccctg     60

tatgccttgt ttgtggaaag aaccagtgac accatcactg agcttcctaa aagttcgaag    120

aagttagagg actatacact ttcttttgaa cttttataat aaatatttgc tctggttttt    180

ggaacccagg gctgttagag gggtgagtga caagtcttac aagtggcctt attccaactc    240

cagaaattgc ccaacggaac tttgagatta tatgcaatcg aaagtgacag gaaacatgcc    300

aactcaatcc ctcttaatgt acatggatgg gccagaagtg attggcagct ctcttggcag    360

tccgatggag atggaggatg ccttgtcaat gaaagggacc gctgttgttc cattccgagc    420

tacacaagaa aaaaatgtca tccaaatcga ggggtatatg cccttggatt gcatgttctg    480

cagccagacc ttcacacatt cagaagacct taataaacat gtcttaatgc aacaccggcc    540

taccctctgt gaaccagcag ttcttcgggt tgaagcagag tatctcagtc cgcttgataa    600

aagtcaagtg cgaacagaac ctcccaagga aaagaattgc aaggaaaatg aatttagctg    660

tgaggtatgt gggcagacat ttagagtcgc ttttgatgtt gagatccaca tgagaacaca    720

caaagattct ttcacttacg ggtgtaacat gtgcggaaga agattcaagg agccttggtt    780

tcttaaaaat cacatgcgga cacataatgg caaatcgggg gccagaagca aactgcagca    840

aggcttggag agtagtccag caacgatcaa cgaggtcgtc caggtgcacg cggccgagag    900

catctcctct ccttacaaaa tctgcatggt ttgtggcttc ctatttccaa ataaagaaag    960

tctaattgag caccgcaagg tgcacaccaa aaaaactgct ttcggtacca gcagcgcgca   1020

gacagactct ccacaaggag gaatgccgtc ctcgagggag gacttcctgc agttgttcaa   1080

cttgagacca aaatctcacc ctgaaacggg gaagaagcct gtcagatgca tccctcagct   1140

cgatccgttc accaccttcc aggcttggca gctggctacc aaaggaaaag ttgccatttg   1200

ccaagaagtg aaggaatcgg ggcaagaagg gagcaccgac aacgacgatt cgagttccga   1260

gaaggagctt ggagaaacaa ataagggcag ttgtgcaggc ctctcgcaag agaaagagaa   1320

gtgcaaacac tcccacggcg aagcgccctc cgtggacgcg gatcccaagt tacccagtag   1380

caaggagaag cccactcact gctccgagtg cggcaaagct ttcagaacct accaccagct   1440

ggtcttgcac tccagggtcc acaagaagga ccggagggcc ggcgcggagt cgcccaccat   1500

gtctgtggac gggaggcagc cggggacgtg ttctcctgac ctcgccgccc ctctggatga   1560

aaatggagcc gtggatcgag gggaaggtgg ttctgaagac ggatctgagg atgggcttcc   1620

cgaaggaatc catctggata aaaatgatga tggaggaaaa ataaaacatc ttacatcttc   1680

aagagagtgt agttattgtg gaaagttttt ccgttcaaat tattacctca atattcatct   1740

cagaacgcat acaggtgaaa aaccatacaa atgtgaattt tgtgaatatg ctgcagccca   1800

gaagacatct ctgaggtatc acttggagag acatcacaag gaaaaacaaa ccgatgttgc   1860

tgctgaagtc aagaacgatg gtaaaaatca ggacactgaa gatgcactat taaccgctga   1920

cagtgcgcaa accaaaaatt tgaaaagatt ttttgatggt gccaaagatg ttacaggcag   1980

tccacctgca aagcagctta aggagatgcc ttctgttttt cagaatgttc tgggcagcgc   2040

tgtcctctca ccagcacaca aagatactca ggatttccat aaaaatgcag ctgatgacag   2100

tgctgataaa gtgaataaaa accctacccc tgcttacctg gacctgttaa aaaagagatc   2160

agcagttgaa actcaggcaa ataacctcat ctgtagaacc aaggcggatg ttactcctcc   2220

tccggatggc agtaccaccc ataaccttga agttagcccc aaagagaagc aaacggagac   2280

cgcagctgac tgcagataca ggccaagtgt ggattgtcac gaaaaacctt taaatttatc   2340

cgtgggggct cttcacaatt gcccggcaat ttctttgagt aaaagtttga ttccaagtat   2400

cacctgtcca ttttgtacct tcaagacatt ttatccagaa gttttaatga tgcaccagag   2460

actggagcat aaatacaatc ctgacgttca taaaaactgt cgaaacaagt ccttgcttag   2520

aagtcgacgt accggatgcc cgccagcgtt gctgggaaaa gatgtgcctc ccctctctag   2580

tttctgtaaa cccaagccca agtctgcttt cccggcgcag tccaaatccc tgccatctgc   2640

gaaggggaag cagagccctc ctgggccagg caaggcccct ctgacttcag ggatagactc   2700

tagcacttta gccccaagta acctgaagtc ccacagacca cagcagaatg tgggggtcca   2760

aggggccgcc accaggcaac agcaatctga gatgtttcct aaaaccagtg tttcccctgc   2820

accggataag acaaaaagac ccgagacaaa attgaaacct cttccagtag ctccttctca   2880

gcccaccctc ggcagcagta acatcaatgg ttccatcgac taccccgcca agaacgacag   2940

cccgtgggca cctccgggaa gagactattt ctgtaatcgg agtgccagca atactgcagc   3000

agaatttggt gagccccttc caaaaagact gaagtccagc gtggttgccc ttgacgttga   3060

ccagcccggg gccaattaca gaagaggcta tgaccttccc aagtaccata tggtcagagg   3120

catcacatca ctgttaccgc aggactgtgt gtatccgtcg caggcgctgc ctcccaaacc   3180

aaggttcctg agctccagcg aggtcgattc tccaaatgtg ctgactgttc agaagcccta   3240

tggtggctcc gggccacttt acacttgtgt gcctgctggt agtccagcat ccagctcgac   3300

gttagaagga aaaaggcctg tgtcatatca acacttatct aacagcatgg cacaaaagag   3360

aaactatgag aattttattg ggaatgcaca ttatcgacca aatgacaaaa aaacttgatt   3420

cactaattag ggggaaaaaa ggtcttggtg gatgtcagtg cttactcccc atgaaattaa   3480

attttacttc atcctttgag aagcgaatgg tgaaagctac tgaaataagc tgtgattgta   3540

ctgtacataa aacatatgag gaatctgcaa ggaacactac agttgtgtaa agttgttctg   3600

ttaacttttg taccaaatag caatacaaac tagttggaac agttggaact tacatacatg   3660

gggactggaa atctctattt tgtccctgaa taatattttt cttagaattg accaaataag   3720

aagtggaatt tttgcatact tgagcgctgc tgaaaagaaa tcatttgggt tgggtggggc   3780

gggatggggg aaaagtatat aatgcttgca cctcaggtaa aaatctgtaa atatctaagt   3840

tgtaaacctg cttgttcaaa tactgtgtgt attccttttc tctaatgcag ctcatcactt   3900

ggagcagttt ctgctattgt gctctttcat ttaaaatgta tgtttttttt tttttaaact   3960

gtcaatgatt ttgtattatg ttgaatccac ccaaatctat tgttgtctta aaattgttaa   4020

tggaagtatt gaccctctat gatatgtgct gcagatatcg aggtcagcca ttcggaagct   4080

ggcagcattt tatcgcaact ttgagcatct cagatgggga aggcaccttc ttcctcgcct   4140

ctccagattg tcctggaacc tccaggatcc ttgactgagg gcgttgggat ggcttgtagg   4200

atttttaaga gagtgtgtct acagacaagc attttctctg tagagcagcc acacgttgta   4260

taaacataaa ctgtatgtgc agttatttaa atttgtttct gtcaaattaa tcatttttgt   4320

tggacgattc agtggcgggg gggttttgcc taaattagta tataaaaaca aaaatgctaa   4380

attatatctg tgaattgcag gtattgggga acagttttaa gggaaatttt ggggggaaca   4440

ttttaggttt gtatttggta gtcttaatgt atctggcatt tgggtgaact gtggacatac   4500

tagagttgat tatagacaca ttgattttga ataaggaact gctggccgag cccgctggga   4560

gtctagaaag agaaaatctg tttctagacc tcagttattt tcccattttt ggttgttttg   4620

aagcagtaac atttttctca gtgcacatgc aatttgggtt ttagagaaga tggccaccag   4680

ctggcttcct agatatttta aacttttgtt ctttaatatg ctgtccatgg ctgagtttat   4740

tagtacatgg gcttagtgac cacaaaatat tttattaaga aactgtttca aaaataaatt   4800

tgcactgttc atttttctgg cctcgctgtt ctccatagag caagggtaat cctagaaaaa   4860

attttttttt tttaaattat gcaacgtaag atgtcctcct tgatagaagt cttagctcct   4920

gtgttacaag ggagaactca tttgagatca gtctgttggc attgcaatga agtgctttgt   4980

atcaggaaag tgtacactat tgaccttttt tcctgttcac aagctgagcc atatgtacat   5040

aatctagatt ttgttttcat agttttgcac ttttatagcc tatttttgaa gattaacaca   5100

tttgcaagat gattgactca atctttgcct aatccaatga gtgttacaga gagcttgctg   5160

tgactagaac cataaatctt aaagggggta tgtgataata gagggctgga atttaaacct   5220

gtatttaaaa aaaagaatca ccaaatctat ttgaaaacaa gtcgatttgt attatgctgg   5280

aattttttgg gctttcagat ttctcttttt aaccacattt ctgaatgtat aaaaatacca   5340

attattttcc tacagccctt tgtacttcaa aatatgtttt tgtgtccatc agtattaact   5400

attggtatac tactggtttt atattttttt ttctttgaga caacagtaca tataatagag   5460

gtacaattcg ttggattttt gtttatgtat ttatttcatt ccagtttgat ttattttaat   5520

tgttgatact taagttgtcg aacagtagac attacttgtt ttatttatga tatatttcag   5580

cttaaagtta tgttattata tgtggaagtg taaatataga tttggtgttt tgcaaaaaaa   5640

aaaaaaaaaa aaa                                                      5653


<210>  553
<211>  3167
<212>  DNA
<213>  Human

<400>  553
aggggcgttg ctgagggtag ctgggggcga gagcgaggct acggagcagg cgagaggcga     60

cggcgagagc tagagcgggc gcagcgttag ggtggccgtg caaggggagc cgtggcccgg    120

gcccggggcg tgcgagacgg cggaagcagc ccagggcctt gctgccgcca tgactgagga    180

atcagaggag acagtcctgt acattgagca ccgctatgtc tgctctgagt gcaaccagct    240

gtatggatca ctggaagagg tgcttatgca ccaaaactcc cacgtgcccc agcagcactt    300

tgagctggtg ggcgtggctg atcccggagt cactgtggcc acagacacag cttcaggcac    360

gggcctctat cagacccttg tgcaggagag ccagtaccag tgcctggagt gtggtcaact    420

gctgatgtca cccagccagc tcctggagca ccaggagctg cacctgaaga tgatggcacc    480

ccaggaggca gtgccagctg agccatcacc taaggcacca cccctgagct ccagcaccat    540

ccactacgag tgtgtggatt gcaaggctct ctttgccagc caggagctct ggctgaacca    600

ccggcagacg cacctccggg ccacacccac caaggctcct gcccctgttg tcctggggtc    660

cccagttgtt ctagggcctc ctgtgggcca ggcccgagtg gctgtggagc actcataccg    720

aaaggcagaa gagggtgggg aaggggcgac tgtcccatct gccgctgcca ccaccactga    780

ggtagtgact gaggtggagc tgctcctcta caagtgctct gagtgctccc agctcttcca    840

gctgccggcg gatttcctgg agcaccaggc cactcacttc cctgctcctg tacccgagtc    900

tcaggagcct gccttacagc aggaggtgca ggcctcgtca cctgcagagg tgcctgtgtc    960

tcagcctgac cccttgccag cttctgacca cagttacgag ctgcgcaatg gtgaagccat   1020

tgggcgggat cgccgggggc gcagggcccg gaggaacaac agtggagaag caggcggggc   1080

agccacacag gagctcttct gctcagcctg tgaccagctc tttctctcac cccaccagct   1140

acagcagcac ctgcggagtc accgggaggg cgtctttaag tgccccctgt gcagtcgtgt   1200

cttccctagc ccttccagtc tggaccagca ccttggagac catagcagcg agtcacactt   1260

cctgtgtgta gactgtggcc tggccttcgg cacagaggcc ctcctcctgg cccaccggcg   1320

agcccacacc ccgaatcctc tgcattcatg tccatgtggg aagacctttg tcaaccttac   1380

caagttcctt tatcaccggc gtactcatgg ggtagggggt gtccctctgc ccacaacacc   1440

agtcccacca gaggaacctg tcattggttt ccctgagcca gccccagcag agactggaga   1500

gccagaggcc cctgagcccc ctgtgtctga ggagacctca gcagggcccg ctgccccagg   1560

cacctaccgc tgcctcctgt gcagccgtga atttggaaag gccttgcagc tgacccggca   1620

ccaacgtttt gtgcatcggc tggagcggcg ccataaatgc agcatttgtg gcaagatgtt   1680

caagaagaag tctcacgtgc gtaaccacct gcgcacacac acaggggagc ggcccttccc   1740

ctgccctgac tgctccaagc ccttcaactc acctgccaac ctggcccgcc accggctcac   1800

acacacagga gagcggccct accggtgtgg ggactgtggc aaggctttca cgcaaagctc   1860

cacactgagg cagcaccgct tggtgcatgc ccagcacttc ccctaccgct gccaggaatg   1920

tggggtgcgt tttcaccgtc cttaccgcct gctcatgcac cgctaccatc acacaggtga   1980

atacccctac aagtgtcgcg agtgcccccg ctccttcttg ctgcgtcggc tgctggaggt   2040

gcaccagctc gtggtccatg ccgggcgcca gccccaccgc tgcccatcct gtggggctgc   2100

cttcccctcc tcactgcggc tccgggagca ccgctgtgca gccgctgctg cccaggcccc   2160

acggcgcttt gagtgtggca cctgtggcaa gaaagtgggc tcagctgctc gactgcaggc   2220

acacgaggcg gcccatgcag ctgctgggcc tggagaggtc ctggctaagg agccccctgc   2280

ccctcgagcc ccacgggcca ctcgtgcacc agttgcctct ccagcagccc ttggaagcac   2340

tgctacagca tcccctgcgg cccctgcccg ccgccggggt ctagagtgca gcgagtgcaa   2400

gaagctgttc agcacagaga cgtcactgca ggtgcaccgg cgcatccaca caggtgagcg   2460

gccataccca tgtccagact gtggcaaagc gttccgtcag agtacccacc tgaaagacca   2520

ccggcgcctg cacacaggtg agcggccctt tgcctgtgaa gtgtgtggca aggcctttgc   2580

catctccatg cgcctggcag aacatcgccg catccacaca ggcgaacgac cctactcctg   2640

ccctgactgt ggcaagagct accgctcctt ctccaacctc tggaagcacc gcaagaccca   2700

tcagcagcag catcaggcag ctgtgcggca gcagctggca gaggcggagg ctgccgttgg   2760

cctggccgtc atggagactg ctgtggaggc gctacccctg gtggaagcca ttgagatcta   2820

ccctctggcc gaggctgagg gggtccagat cagtggctga ctctgcccga cttcctcttt   2880

ggcacctcca ttccctgttg ctgaaggccc tccagcatcc ccttaagcat ctgtacatac   2940

tgtgtccctt cctcttccca tccccaccac cttgtaagtt ctaaattgga tttattctct   3000

cgtgaggggg gtgctctggg gtccttgaca cacataaagg tgccccccca ccttccacct   3060

cttagcactg gtgaccccaa aaatgaaacc atcaataaag actgagttgc cagcagtgtg   3120

tagagtggaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa                 3167


<210>  554
<211>  3363
<212>  DNA
<213>  Human

<400>  554
gctttttgac agctgtctct tgcacagccg cagccaagtc cggtgggttc gggaacctgt     60

ggcccggctc tctgcgcgtc cccatccccc gtggccccga ccccggccat gaagcgtatc    120

ttctcctgct ccagcacaca ggtggcggtg gagagatgga accgccatga tcagaagctg    180

ctggaggcag tgcacagggg ggatgtggga cgcgtggctg ccctggcctc caggaaatct    240

gcccgaccca ccaagcttga ctcgaatggc cagtccccgt ttcatctggc agcctccaaa    300

ggcctgacag aatgtctgac tatcctgctt gcaaatgggg ctgacatcaa cagcaagaat    360

gaggatggaa gcactgccct acacttggcc accatctcct gccagccaca gtgtgttaag    420

gttctgcttc agcatggtgc taatgaagat gctgtggatg cagaaaaccg tagtccattg    480

cactgggcag cctcctctgg ctgtgcctca agtgtgctcc tgctgtgtga ccacgaagcc    540

ttcctggacg tgttggataa tgatggacgt acacccctga tgatcgcatc gctgggtggg    600

cacgcagcta tctgctcaca gctgctgcag cgaggcgccc gagttaatgt tacagacaag    660

aatgacaaat cggctttgat cctggcctgt gagaaaggca gtgccgaggt ggctgaactg    720

ctcctgagcc acggagctga cgcgggggct gtggacagca cagggcatga tgctctgcac    780

tatgctctgc acacacaaga caaggcactg tggaggcacc tacagcaggc cctgagccgg    840

cggcggcggg gcggtcagag gctagtccag cacccagatc tcgcatccca ggcctctcca    900

tctgagcccc aggcaggttc tcctcctaag agctcatgga gagcagagcc tgaagaggag    960

caagaggaga aggaggatga agacccgtgc tcggaggagt ggaggtggaa gtatgaagag   1020

gagcggagga aagttgttcg gctggagcag gagctggtgc aaaagacaga agagtgtaag   1080

actcaagctg cagcctatct ggaccttgag aaccagattc gagagcaggc gcaggagcta   1140

ggggtcctcc tatcctggga gcccagagct tcaggaaagc aaggctctag tctccggcct   1200

ggaggggatg gcatggagca gggttgtcct aaggacctgc tggctgagag tacacaagag   1260

ctaaagaagc agcagcaggc agcagccaca gtaaatccag tattagctcc aaagaaggct   1320

gaggactcag ccccaggaaa gatccagtat gaagtccatg gaaggtccca accagaagaa   1380

caggggccac cccagagccc agcgtctgag accatcagga aagccacagg acagcaactg   1440

actaccaatg gggcacagac ctttggccct gatcatgctg accagctgcc tgctggtcag   1500

aaggagagtt cccaggttct aggagttgaa ccaggaggca cagtggctga accagtgggc   1560

ccagcagcca tgaaccagct tctgcttcaa ctaagggagg agcttgctgc agtgtggcga   1620

gaaaaggatg ctgcccgggg ggctttgtca agaccggtca tggagggagc cctggggact   1680

ccccgtgctg aggcagcagc agctgcctgg gagaagatgg aagcccgact ggagcgggtg   1740

ctggcaaggc tggaatgggc aaaggcagga ctacaggtga aacctgaggt tccttcccag   1800

gagtccagag agggagccct aaaggcagcc ccagggagca tcaaacagga tgaagagaag   1860

gagaaaaggg ttcctggggc tcgaggagag cctctagggg cccttggagg ggaaaaggcc   1920

ctaggaggcc tggcaaaggg acagctggag aaggagatgt cagtactgag actgagcaac   1980

agtaacttgc tggaggagtt aggggagttg gggcgggagc ggcagaggtt gcagagggag   2040

ctacagtccc tgagccagcg gctgcagcgg gagtttgtgc ccaagccaga ggcgcaggtc   2100

cagctacagc agttgcgaca gagtgtgggg ctgctgacaa atgaactggc catggagaag   2160

gaggccacag agaagctgcg gaagctcctg gcctcccaga gcagcggtct ccgagggctg   2220

tgggactgcc tgcccgcaga cctagtgggc gagaggagtg cacaaagcaa agcagcggag   2280

tccctggagg agctgcgggc ctgcatcagc accctggtgg atcggcaccg ggaggcccag   2340

caggtgctgg ctcggctgca agaagaaaac cagcagttgc gggggtcctt gtccccgtgt   2400

agggagccag gcacctcctt aaaggcccca gcatcccccc aagtggccgc tctggagcaa   2460

gacctgggga agctggagga agagctgcgg gcagttcagg ccacgatgag cgggaagagc   2520

caggagatcg gaaagctgaa gcagctgctc taccaagcca cagaggaagt ggctgagcta   2580

agggcccggg aggcagccag cctacggcaa cacgagaaaa ctcggggttc gctggtggcc   2640

caggctcagg cttggggcca ggagctaaag gctctgttgg aaaagtataa tacggcctgc   2700

cgggaagtgg gtcggctgcg ggaggcggtg gccgaggagc gccgccggag cggggacctg   2760

gccgctcagg cagccgaaca agagcgccag gccagcgaga tgcgggggcg ctccgagcag   2820

tttgagaaaa cggcagagct gctgaaagag aagatggagc atctcattgg ggcttgccga   2880

gacaaggaag ccaagatcaa ggagttgttg aagaagctgg agcagctttc agaagaggtt   2940

ctagcaattc ggggagaaaa tgctcgcctt gccctgcagc tgcaggattc ccagaagaac   3000

catgaagaga tcatctccac ctacaggaat catctactga atgctgctcg gggttacatg   3060

gaacatgaag tgtacaatat cctgctgcaa atccttagca tggaagagga gtgaggcagc   3120

ctcactgtgt gccctcaggg atacgagatt ctctgttgga ataagaaacc ctggttgaca   3180

gaggcttcat caggctgtgg tgggcggggg tgttggccac taggcaatgg tatgggcagg   3240

gcttcacctg acattatgga cctcagacct gagaacctgg accctggaat cagcatggat   3300

gagaccagag gaggtatgga tggaaacaag ctctatggaa aataaagcat gaggcaggac   3360

ggg                                                                 3363


<210>  555
<211>  1549
<212>  DNA
<213>  Human

<400>  555
gccatccgcc ctccacacga ttcagcccgg tggtgttagc cccctggact cgattcctga     60

ggcaaacagt gccccttaag gtcggcgaca gcctcttctg ggttcactgc agtccaaccg    120

gttccctacc ctctgccatt atgaacatcc gcaacgctca gccagacgac ctgatgaata    180

tgcaacactg caacctcctt tgccttcctg agaactacca gatgaaatac tatttatatc    240

atggcctttc ctggccccag ctttcttaca tcgctgagga tgaggacggg aagattgtgg    300

gctatgttct ggccaaaatg gaggaggaac cagatgatgt cccgcatggc catatcacct    360

cactggccgt gaagcgttca caccggcgcc tcggcctggc ccagaagctg atggaccagg    420

cctccagggc catgatagag aactttaacg ccaaatacgt gtctctgcac gtcaggaaga    480

gtaaccggcc agccttgcac ctttattcta acaccctcaa ctttcagatt agtgaggtgg    540

aacctaaata ctatgcagat ggggaagatg cttatgctat gaagcgggat ctctcgcaga    600

tggcagatga gctgagacga caaatggacc tgaagaaggg cgggtatgtg gtcctgggct    660

ccagggagaa ccaggagacc cagggcagca cactttctga ttctgaagag gcctgtcagc    720

aaaagaaccc ggctaccgaa gaaagtggca gtgacagcaa agaacctaag gagtctgtgg    780

agagcaccaa cgtccaggac agctcagaaa gctcggattc cacctcctag agcatgctta    840

agcatttcag gtcctcatgt ctcaaccaca tctactctgt gaaccctggc ttagtctgtc    900

tgctctgcag catctgctgt ggggatcatc tcacagtgac cagaatggct tctcactctt    960

aactctataa acaaccacct ttcacatatc ctgctgggat catgaaggaa tacctggaca   1020

caagagccac tgcacaacag ccaaggaact ttgagacctg ccattacaga acctttcttg   1080

gcctactcac actacgctgc cattttattc tgtttgtagt agtcctctgt tgggtgtggt   1140

tatcctgcaa gtttttctcc ttttagaatg atgaacagga agcagggcaa actcttgaag   1200

atttccagct ttcagttttt gtttttgttt tttaaccatt atttacctga gttttcatcc   1260

ttgaggaggt gaagtagtca ggaccatgaa gtcagacctc atgccctctt cctcctcttt   1320

cctggaagaa gtattcagtt tccttttcct ttctctggta actcctcctt tatactattc   1380

ccccctccct tttttttgag gaggagggca tcaccttccc agtgggaaaa ggtgttaagt   1440

taggagcttc tactgtacaa tcagaacttg gagattttaa gaaaaggaca aacggtaatt   1500

aaattggaat ctctaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa               1549


<210>  556
<211>  7224
<212>  DNA
<213>  Human

<400>  556
gtaccttgat ttcgtattct gagaggctgc tgcttagcgg tagccccttg gtttccgtgg     60

caacggaaaa gcgcgggaat tacagataaa ttaaaactgc gactgcgcgg cgtgagctcg    120

ctgagacttc ctggacgggg gacaggctgt ggggtttctc agataactgg gcccctgcgc    180

tcaggaggcc ttcaccctct gctctgggta aagttcattg gaacagaaag aaatggattt    240

atctgctctt cgcgttgaag aagtacaaaa tgtcattaat gctatgcaga aaatcttaga    300

gtgtcccatc tgtctggagt tgatcaagga acctgtctcc acaaagtgtg accacatatt    360

ttgcaaattt tgcatgctga aacttctcaa ccagaagaaa gggccttcac agtgtccttt    420

atgtaagaat gatataacca aaaggagcct acaagaaagt acgagattta gtcaacttgt    480

tgaagagcta ttgaaaatca tttgtgcttt tcagcttgac acaggtttgg agtatgcaaa    540

cagctataat tttgcaaaaa aggaaaataa ctctcctgaa catctaaaag atgaagtttc    600

tatcatccaa agtatgggct acagaaaccg tgccaaaaga cttctacaga gtgaacccga    660

aaatccttcc ttgcaggaaa ccagtctcag tgtccaactc tctaaccttg gaactgtgag    720

aactctgagg acaaagcagc ggatacaacc tcaaaagacg tctgtctaca ttgaattggg    780

atctgattct tctgaagata ccgttaataa ggcaacttat tgcagtgtgg gagatcaaga    840

attgttacaa atcacccctc aaggaaccag ggatgaaatc agtttggatt ctgcaaaaaa    900

ggctgcttgt gaattttctg agacggatgt aacaaatact gaacatcatc aacccagtaa    960

taatgatttg aacaccactg agaagcgtgc agctgagagg catccagaaa agtatcaggg   1020

tagttctgtt tcaaacttgc atgtggagcc atgtggcaca aatactcatg ccagctcatt   1080

acagcatgag aacagcagtt tattactcac taaagacaga atgaatgtag aaaaggctga   1140

attctgtaat aaaagcaaac agcctggctt agcaaggagc caacataaca gatgggctgg   1200

aagtaaggaa acatgtaatg ataggcggac tcccagcaca gaaaaaaagg tagatctgaa   1260

tgctgatccc ctgtgtgaga gaaaagaatg gaataagcag aaactgccat gctcagagaa   1320

tcctagagat actgaagatg ttccttggat aacactaaat agcagcattc agaaagttaa   1380

tgagtggttt tccagaagtg atgaactgtt aggttctgat gactcacatg atggggagtc   1440

tgaatcaaat gccaaagtag ctgatgtatt ggacgttcta aatgaggtag atgaatattc   1500

tggttcttca gagaaaatag acttactggc cagtgatcct catgaggctt taatatgtaa   1560

aagtgaaaga gttcactcca aatcagtaga gagtaatatt gaagacaaaa tatttgggaa   1620

aacctatcgg aagaaggcaa gcctccccaa cttaagccat gtaactgaaa atctaattat   1680

aggagcattt gttactgagc cacagataat acaagagcgt cccctcacaa ataaattaaa   1740

gcgtaaaagg agacctacat caggccttca tcctgaggat tttatcaaga aagcagattt   1800

ggcagttcaa aagactcctg aaatgataaa tcagggaact aaccaaacgg agcagaatgg   1860

tcaagtgatg aatattacta atagtggtca tgagaataaa acaaaaggtg attctattca   1920

gaatgagaaa aatcctaacc caatagaatc actcgaaaaa gaatctgctt tcaaaacgaa   1980

agctgaacct ataagcagca gtataagcaa tatggaactc gaattaaata tccacaattc   2040

aaaagcacct aaaaagaata ggctgaggag gaagtcttct accaggcata ttcatgcgct   2100

tgaactagta gtcagtagaa atctaagccc acctaattgt actgaattgc aaattgatag   2160

ttgttctagc agtgaagaga taaagaaaaa aaagtacaac caaatgccag tcaggcacag   2220

cagaaaccta caactcatgg aaggtaaaga acctgcaact ggagccaaga agagtaacaa   2280

gccaaatgaa cagacaagta aaagacatga cagcgatact ttcccagagc tgaagttaac   2340

aaatgcacct ggttctttta ctaagtgttc aaataccagt gaacttaaag aatttgtcaa   2400

tcctagcctt ccaagagaag aaaaagaaga gaaactagaa acagttaaag tgtctaataa   2460

tgctgaagac cccaaagatc tcatgttaag tggagaaagg gttttgcaaa ctgaaagatc   2520

tgtagagagt agcagtattt cattggtacc tggtactgat tatggcactc aggaaagtat   2580

ctcgttactg gaagttagca ctctagggaa ggcaaaaaca gaaccaaata aatgtgtgag   2640

tcagtgtgca gcatttgaaa accccaaggg actaattcat ggttgttcca aagataatag   2700

aaatgacaca gaaggcttta agtatccatt gggacatgaa gttaaccaca gtcgggaaac   2760

aagcatagaa atggaagaaa gtgaacttga tgctcagtat ttgcagaata cattcaaggt   2820

ttcaaagcgc cagtcatttg ctccgttttc aaatccagga aatgcagaag aggaatgtgc   2880

aacattctct gcccactctg ggtccttaaa gaaacaaagt ccaaaagtca cttttgaatg   2940

tgaacaaaag gaagaaaatc aaggaaagaa tgagtctaat atcaagcctg tacagacagt   3000

taatatcact gcaggctttc ctgtggttgg tcagaaagat aagccagttg ataatgccaa   3060

atgtagtatc aaaggaggct ctaggttttg tctatcatct cagttcagag gcaacgaaac   3120

tggactcatt actccaaata aacatggact tttacaaaac ccatatcgta taccaccact   3180

ttttcccatc aagtcatttg ttaaaactaa atgtaagaaa aatctgctag aggaaaactt   3240

tgaggaacat tcaatgtcac ctgaaagaga aatgggaaat gagaacattc caagtacagt   3300

gagcacaatt agccgtaata acattagaga aaatgttttt aaagaagcca gctcaagcaa   3360

tattaatgaa gtaggttcca gtactaatga agtgggctcc agtattaatg aaataggttc   3420

cagtgatgaa aacattcaag cagaactagg tagaaacaga gggccaaaat tgaatgctat   3480

gcttagatta ggggttttgc aacctgaggt ctataaacaa agtcttcctg gaagtaattg   3540

taagcatcct gaaataaaaa agcaagaata tgaagaagta gttcagactg ttaatacaga   3600

tttctctcca tatctgattt cagataactt agaacagcct atgggaagta gtcatgcatc   3660

tcaggtttgt tctgagacac ctgatgacct gttagatgat ggtgaaataa aggaagatac   3720

tagttttgct gaaaatgaca ttaaggaaag ttctgctgtt tttagcaaaa gcgtccagaa   3780

aggagagctt agcaggagtc ctagcccttt cacccataca catttggctc agggttaccg   3840

aagaggggcc aagaaattag agtcctcaga agagaactta tctagtgagg atgaagagct   3900

tccctgcttc caacacttgt tatttggtaa agtaaacaat ataccttctc agtctactag   3960

gcatagcacc gttgctaccg agtgtctgtc taagaacaca gaggagaatt tattatcatt   4020

gaagaatagc ttaaatgact gcagtaacca ggtaatattg gcaaaggcat ctcaggaaca   4080

tcaccttagt gaggaaacaa aatgttctgc tagcttgttt tcttcacagt gcagtgaatt   4140

ggaagacttg actgcaaata caaacaccca ggatcctttc ttgattggtt cttccaaaca   4200

aatgaggcat cagtctgaaa gccagggagt tggtctgagt gacaaggaat tggtttcaga   4260

tgatgaagaa agaggaacgg gcttggaaga aaataatcaa gaagagcaaa gcatggattc   4320

aaacttaggt gaagcagcat ctgggtgtga gagtgaaaca agcgtctctg aagactgctc   4380

agggctatcc tctcagagtg acattttaac cactcagcag agggatacca tgcaacataa   4440

cctgataaag ctccagcagg aaatggctga actagaagct gtgttagaac agcatgggag   4500

ccagccttct aacagctacc cttccatcat aagtgactct tctgcccttg aggacctgcg   4560

aaatccagaa caaagcacat cagaaaaagc agtattaact tcacagaaaa gtagtgaata   4620

ccctataagc cagaatccag aaggcctttc tgctgacaag tttgaggtgt ctgcagatag   4680

ttctaccagt aaaaataaag aaccaggagt ggaaaggtca tccccttcta aatgcccatc   4740

attagatgat aggtggtaca tgcacagttg ctctgggagt cttcagaata gaaactaccc   4800

atctcaagag gagctcatta aggttgttga tgtggaggag caacagctgg aagagtctgg   4860

gccacacgat ttgacggaaa catcttactt gccaaggcaa gatctagagg gaacccctta   4920

cctggaatct ggaatcagcc tcttctctga tgaccctgaa tctgatcctt ctgaagacag   4980

agccccagag tcagctcgtg ttggcaacat accatcttca acctctgcat tgaaagttcc   5040

ccaattgaaa gttgcagaat ctgcccagag tccagctgct gctcatacta ctgatactgc   5100

tgggtataat gcaatggaag aaagtgtgag cagggagaag ccagaattga cagcttcaac   5160

agaaagggtc aacaaaagaa tgtccatggt ggtgtctggc ctgaccccag aagaatttat   5220

gctcgtgtac aagtttgcca gaaaacacca catcacttta actaatctaa ttactgaaga   5280

gactactcat gttgttatga aaacagatgc tgagtttgtg tgtgaacgga cactgaaata   5340

ttttctagga attgcgggag gaaaatgggt agttagctat ttctgggtga cccagtctat   5400

taaagaaaga aaaatgctga atgagcatga ttttgaagtc agaggagatg tggtcaatgg   5460

aagaaaccac caaggtccaa agcgagcaag agaatcccag gacagaaaga tcttcagggg   5520

gctagaaatc tgttgctatg ggcccttcac caacatgccc acagatcaac tggaatggat   5580

ggtacagctg tgtggtgctt ctgtggtgaa ggagctttca tcattcaccc ttggcacagg   5640

tgtccaccca attgtggttg tgcagccaga tgcctggaca gaggacaatg gcttccatgc   5700

aattgggcag atgtgtgagg cacctgtggt gacccgagag tgggtgttgg acagtgtagc   5760

actctaccag tgccaggagc tggacaccta cctgataccc cagatccccc acagccacta   5820

ctgactgcag ccagccacag gtacagagcc acaggacccc aagaatgagc ttacaaagtg   5880

gcctttccag gccctgggag ctcctctcac tcttcagtcc ttctactgtc ctggctacta   5940

aatattttat gtacatcagc ctgaaaagga cttctggcta tgcaagggtc ccttaaagat   6000

tttctgcttg aagtctccct tggaaatctg ccatgagcac aaaattatgg taatttttca   6060

cctgagaaga ttttaaaacc atttaaacgc caccaattga gcaagatgct gattcattat   6120

ttatcagccc tattctttct attcaggctg ttgttggctt agggctggaa gcacagagtg   6180

gcttggcctc aagagaatag ctggtttccc taagtttact tctctaaaac cctgtgttca   6240

caaaggcaga gagtcagacc cttcaatgga aggagagtgc ttgggatcga ttatgtgact   6300

taaagtcaga atagtccttg ggcagttctc aaatgttgga gtggaacatt ggggaggaaa   6360

ttctgaggca ggtattagaa atgaaaagga aacttgaaac ctgggcatgg tggctcacgc   6420

ctgtaatccc agcactttgg gaggccaagg tgggcagatc actggaggtc aggagttcga   6480

aaccagcctg gccaacatgg tgaaacccca tctctactaa aaatacagaa attagccggt   6540

catggtggtg gacacctgta atcccagcta ctcaggtggc taaggcagga gaatcacttc   6600

agcccgggag gtggaggttg cagtgagcca agatcatacc acggcactcc agcctgggtg   6660

acagtgagac tgtggctcaa aaaaaaaaaa aaaaaaagga aaatgaaact agaagagatt   6720

tctaaaagtc tgagatatat ttgctagatt tctaaagaat gtgttctaaa acagcagaag   6780

attttcaaga accggtttcc aaagacagtc ttctaattcc tcattagtaa taagtaaaat   6840

gtttattgtt gtagctctgg tatataatcc attcctctta aaatataaga cctctggcat   6900

gaatatttca tatctataaa atgacagatc ccaccaggaa ggaagctgtt gctttctttg   6960

aggtgatttt tttcctttgc tccctgttgc tgaaaccata cagcttcata aataattttg   7020

cttgctgaag gaagaaaaag tgtttttcat aaacccatta tccaggactg tttatagctg   7080

ttggaaggac taggtcttcc ctagcccccc cagtgtgcaa gggcagtgaa gacttgattg   7140

tacaaaatac gttttgtaaa tgttgtgctg ttaacactgc aaataaactt ggtagcaaac   7200

acttccaaaa aaaaaaaaaa aaaa                                          7224


<210>  557
<211>  1969
<212>  DNA
<213>  Human

<400>  557
tgaggtttgg tctctgttgt cacaacattc agtacaatct gctgcccagg acctggacat     60

tgacagataa aatgaagtgg gaagaatatg aagaactgct tcattatgct atagtgactc    120

caaatattga accctgtgct tcacagtcat ctcatcctaa gggagaattg gtgccagatg    180

tcagaatttc tacaattcat gatattcttc atagtcaagg aaataactct gaagtaagag    240

aaactgcaat agaagttgga aaaggatgtg atttccatat ttcaagtcat tcaaagacag    300

atgagtcatc accagtgtta tcgccaagga agccttctca cccagtcatg gattttttca    360

gttcacatct tttagctgac tcttcctcac cagcaacaaa ttctagtcat acagatgccc    420

atgaaatact tgtgagcgat tttcttgttt ctgatgaaaa ccttcagaag atggaaaatg    480

tgcttgatct ttggagttca ggtcttaaga caaacatcat atctgaacta agtaaatgga    540

gacttaattt tattgactgg caccgaatgg aaatgagaaa agagaaagaa aaacatgcag    600

cacatttaaa acaactgtgt aatcagatca atgaattgaa ggagctgcaa aaaacctttg    660

aaatctccat tgggagaaaa gatgaggtga tttctagctt gtctcatgcc ataggcaagc    720

aaaaggaaaa gatagagttg atgagaacat tcttccactg gcgaatcggc catgtcagag    780

ccagacagga tgtttatgaa ggtaaactag ctgaccagta ctaccagaga actttactga    840

agaaagtctg gaaagtctgg cgttccgtag tgcaaaagca gtggaaagat gtggtagaaa    900

gagcttgtca agcaagagct gaagaagttt gtatccagat ttccaatgat tatgaagcca    960

aagttgctat gttatctgga gctttggaaa atgcaaaagc tgagattcaa agaatgcaac   1020

atgaaaaaga gcactttgaa gattccatga aaaaagcttt catgaggggt gtatgtgcat   1080

taaatcttga agccatgact atatttcaaa acagaaatga tgcagggata gactccacaa   1140

ataataaaaa ggaagagtat ggtcctggtg ttcaaggaaa agaacattct gctcatttgg   1200

atccttcagc tcctccgatg cccttaccag ttacatcacc actgctgcca tccccaccag   1260

ccgccgtcgg aggagccagc gcgactgccg ttccctcagc tgcttcgatg acttctacca   1320

gggctgcttc cgcatcttct gttcacgttc ctgtttctgc tcttggtgca ggatctgcag   1380

ctactgctgc atcagaagaa atgtatgtgc caagagttgt aacctctgca caacagaaag   1440

caggaagaac tattacagcc cggatcacag gaagatgtga ttttgcttca aaaaatagaa   1500

ttagcagcag tttagctata atgggagttt ctcctcccat gagctcagtt gttgtggaaa   1560

aacatcatcc agtcacagtg caaaccattc ctcaagcaac tgcagcaaaa tatccccgga   1620

ccattcatcc tgaaagtagt acctcagctt ccagatcact tggaaccaga tcagctcaca   1680

cccagtctct cacaagtgtt cattccataa aagtggttga ctaaagtgaa tatgtccata   1740

gtggggtctt ttaatccctc tggtcttacc aagggttaga agtcttttgg ttttaacttt   1800

tccatattgt tagaacatca tggagacatc atgttcatct gttcaaaatt acaagaggct   1860

ttttcaagct ctaccatgct ttgtaactat atgtagaaat tattttaatg ttatttttta   1920

tttaagcaat taagtaaaac ttttttaaat taaaaaagaa aaaaaaaaa               1969


<210>  558
<211>  1082
<212>  DNA
<213>  Human

<400>  558
ccgtcctgga ggaagaacgg cacagacgga gggaggctgg ggttggcaga gactgggacg     60

gaagtccctc agtcccccag gagcctcctt catggacccg gggatcccaa gaggggctgc    120

ctcaacttag gatgggcaac tgtgtcaagt atccactgag aaatctctca aggaaggata    180

gatcactgcg accagaggaa attgaagagc tccgagaggc cttcagagaa ttcgacaagg    240

acaaggatgg ctacatcaac tgccgggatc tgggcaactg catgcgcacc atgggctaca    300

tgcccaccga gatggagctc atcgaactgt cccagcagat caacatgaac ctgggtggcc    360

atgtagattt tgatgacttc gtggagctaa tggggcctaa actcctggca gagacagcag    420

atatgattgg tgtaaaggaa ctgcgagatg ctttccgaga gtttgacacc aatggtgatg    480

gggaaataag caccagtgag ctgcgagagg ctatgaggaa gctcctgggt catcaggtgg    540

gacaccgaga catagaggaa attatccgag atgtggacct caatggggat ggacgagtgg    600

actttgaaga gtttgtccgg atgatgtccc gctgaggccg cgagggcccc tccaggactg    660

ccaagctccc aaaggcgggg ctaagaggag ctagagcttg cctcacccgc tgtagccgcc    720

gagagcccag gatgtactgg cggatggggc ctgcctgcac cccggggagg cgcccacccc    780

ggacccccac ccctccgcac tgtgaaagac taactcctgc aactggaaag cgggggcgcc    840

cgccgacgag gaggccaccg tgccaagccg gcagaggtca tgccaggcgc caagggccat    900

gtgcccagct gctgctggct gggtgggcca gggagcccgc cagcagaccc cacacagcat    960

gtccgcccca gggcaaagcc tcccaccttc gctctgcgcc cgtcccagct cgcctcagcc   1020

ctgttatctc agaaccaata aaaatatttc caagagcaaa aaaaaaaaaa aaaaaaaaaa   1080

aa                                                                  1082


<210>  559
<211>  1557
<212>  DNA
<213>  Human

<400>  559
agcgacaggc cccgcccccg ccaaccgcct cgcgccttcc gtcgcccggt ttccatggtg     60

acggggcgcc aggctagggc ggcctggcca ctgagccggg gtgcagtggc agcgggagag    120

tacctggcga tggcgatatg agcggtgcgg gggtggcggc tgggacgcgg ccccccagct    180

cgccgacccc gggctctcgg cgccggcgcc agcgcccctc tgtgggcgtc cagtccttga    240

ggccgcagag cccgcagctc aggcagagcg acccgcagaa acggaacctg gacctggaga    300

aaagcctgca gttcctgcag cagcagcact cggagatgct ggccaagctc catgaggaga    360

tcgagcatct gaagcgggaa aacaaggatc tccattacaa gctcataatg aatcagacat    420

cacagaagaa agatggcccc tcaggaaacc acctttccag ggcctctgct cccttgggcg    480

ctcgctgggt ctgcatcaac ggagtgtggg tagagccggg aggacccagc cctgccaggc    540

tgaaggaggg ctcctcacgg acacacaggc caggaggcaa gcgtgggcgt cttgcgggcg    600

gtagcgccga cactgtgcgc tctcctgcag acagcctctc catgtcaagc ttccagtctg    660

tcaagtccat ctctaattca ggcaaggcca ggccccagcc cggctccttc aacaagcaag    720

attcaaaagc tgacgtctcc cagaaggcgg acctggaaga ggagccccta cttcacaaca    780

gcaagctgga caaagttcct ggggtacaag ggcaggccag aaaggagaaa gcagaggcct    840

ctaatgcagg agctgcctgt atggggaaca gccagcacca gggcaggcag atgggggcgg    900

gggcacaccc cccaatgatc ctgccccttc ccctgcgaaa gcccaccaca cttaggcagt    960

gcgaagtgct catccgcgag ctgtggaata ccaacctcct gcagacccaa gagctgcggc   1020

acctcaagtc cctcctggaa gggagccaga ggccccaggc agccccggag gaagctagct   1080

ttcccaggga ccaagaagcc acgcatttcc ccaaggtctc caccaagagc ctctccaaga   1140

aatgcctgag cccacctgtg gcggagcgtg ccatcctgcc cgcactgaag cagaccccga   1200

agaacaactt tgccgagagg cagaagaggc tgcaggcaat gcagaaacgg cgcctgcatc   1260

gctcagtgct ttgagccacc ccaatctggt cagtgccagg cccaccaacc tgcagctgga   1320

gactggctct ctatagcatt tcctgatact tccgctactt ttaggcctgg ctaaattcca   1380

agacagataa cactcaagat agataaagta cttgatctcc aaactgacaa actgtttatt   1440

ttctagctgt tattttgcta tttggcattt acataaaagc acacgatgaa gcaggtatcg   1500

ccttacctgt tgaaactgaa aataaagctt gtttatttcc aaaaaaaaaa aaaaaaa      1557


<210>  560
<211>  1068
<212>  DNA
<213>  Human

<400>  560
cgccggagga gttctgcgtc tcggggtggt gactgggtcc agaatggctt cggattcggg     60

gaaccagggg accctctgca cgttggagtt cgcggtgcag atgacctgtc agagctgtgt    120

ggacgcggtg cgcaaatccc tgcaaggggt ggcaggtgtc caggatgtgg aggtgcactt    180

ggaggaccag atggtcttgg tacacaccac tctacccagc caggaggtgc aggctctcct    240

ggaaggcacg gggcggcagg cggtactcaa gggcatgggc agcggccagt tgcagaatct    300

gggggcagca gtggccatcc tgggggggcc tggcaccgtg cagggggtgg tgcgcttcct    360

acagctgacc cctgagcgct gcctcatcga gggaactatt gacggcctgg agcctgggct    420

gcatggactc cacgtccatc agtacgggga ccttacaaac aactgcaaca gctgtgggaa    480

tcactttaac cctgatggag catctcatgg gggcccccag gactctgacc ggcaccgcgg    540

agacctgggc aatgtccgtg ctgatgctga cggccgcgcc atcttcagaa tggaggatga    600

gcagctgaag gtgtgggatg tgattggccg cagcctgatt attgatgagg gagaagatga    660

cctgggccgg ggaggccatc ccttatccaa gatcacaggg aactccgggg agaggttggc    720

ctgtggcatc attgcacgct ccgctggcct tttccagaac cccaagcaga tctgctcttg    780

cgatggcctc accatctggg aggagcgagg ccggcccatc gctggcaagg gccgaaagga    840

gtcagcgcag ccccctgccc acctttgagc aggacctcac cttggctctg ttgctgtcct    900

ccagggcgag cactttccac ttccagaggg ggccagaggg actttgcctg cccagtcttt    960

ggagagctca gtacagggca ggagctgctg tggtgttccc ttggcaaatg aaagttttat   1020

tttcgtttgg gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa                1068


<210>  561
<211>  691
<212>  DNA
<213>  Human

<400>  561
gacccctcac actcacctag ccaccatgga catcgccatc caccacccct ggatccgccg     60

ccccttcttt cctttccact cccccagccg cctctttgac cagttcttcg gagagcacct    120

gttggagtct gatcttttcc cgacgtctac ttccctgagt cccttctacc ttcggccacc    180

ctccttcctg cgggcaccca gctggtttga cactggactc tcagagatgc gcctggagaa    240

ggacaggttc tctgtcaacc tggatgtgaa gcacttctcc ccagaggaac tcaaagttaa    300

ggtgttggga gatgtgattg aggtgcatgg aaaacatgaa gagcgccagg atgaacatgg    360

tttcatctcc agggagttcc acaggaaata ccggatccca gctgatgtag accctctcac    420

cattacttca tccctgtcat ctgatggggt cctcactgtg aatggaccaa ggaaacaggt    480

ctctggccct gagcgcacca ttcccatcac ccgtgaagag aagcctgctg tcaccgcagc    540

ccccaagaaa tagatgccct ttcttgaatt gcatttttta aaacaagaaa gtttccccac    600

cagtgaatga aagtcttgtg actagtgctg aagcttatta atgctaaggg caggcccaaa    660

ttatcaagct aataaaatat cattcagcaa c                                   691


<210>  562
<211>  6025
<212>  DNA
<213>  Human

<400>  562
gtagaggcgg aagttgaggg gactgacgca gatgggggaa ttttgcctcg atggcacttt     60

cctgtccgcg actccgcccc caccagaggg gctaggctct gggattcaag atggaggcgc    120

tgagtcgagc tgggcaggag atgagcctag cggccctgaa gcaacacgac ccctatatca    180

ccagcatcgc agacctcacg ggccaggtcg ctctgtacac cttctgcccc aaggccaacc    240

agtgggagaa gactgatata gaagggacct tattcgtata tcgaaggtca gcttcccctt    300

accatggttt taccattgtg aatcgactaa atatgcacaa tctagttgaa ccagtgaata    360

aagatttgga atttcagctc catgaaccat ttcttctgta tagaaatgca agcttgtcga    420

tatatagtat ctggttttat gacaagaatg actgtcaccg catagcaaaa ctcatggctg    480

atgtggtaga agaggagaca cggcgatccc agcaagctgc tcgggacaaa cagagtccca    540

gccaggccaa tggctgcagc gaccacaggc ccatcgacat cctggagatg ctgagcagag    600

ccaaggatga gtatgagagg aatcagatgg gtgactcaaa tatctccagc cctgggttac    660

agccaagcac tcagctctcc aatctgggaa gcaccgagac tctagaagaa atgccctccg    720

ggtcacagga taagtctgct ccatctggac acaagcatct gacggtagaa gagttatttg    780

gaacctcttt gccaaaggaa caaccagcag ttgtgggtct ggattcagaa gaaatggaga    840

ggttgccagg agatgcctcc cagaaagagc ccaattcatt cctaccattt ccctttgagc    900

agttaggagg agcccctcaa tcagaaaccc tgggtgtccc ttctgctgcc caccattcag    960

tccagcctga aatcaccacc ccggtgctaa tcactccagc ctccatcaca cagtccaatg   1020

aaaagcatgc tccaacctac acaatcccgt tgagccctgt tctcagtccc actctgccag   1080

ctgaagctcc tactgcacag gttcccccca gcttacctcg aaacagcacc atgatgcagg   1140

cagtgaagac cacgcctaga cagaggtctc cactcctgaa ccagccagtc cctgagctaa   1200

gccatgccag tctgattgcc aaccagagcc ccttcagggc cccattgaac gtgacgaaca   1260

cagctggcac atccctccca agcgttgatc ttctccagaa actcaggttg accccacagc   1320

atgaccaaat acagacacaa ccacttggga aaggtgcaat ggtagccagc ttttctccgg   1380

cagctggtca gctagccaca cctgagagct tcatagagcc tccctctaag acagcagcag   1440

caagagtggc ggcctcagcc tccctgagca acatggtgct tgctcccctt cagtctatgc   1500

agcagaacca ggatcctgaa gtatttgtgc agcctaaggt gttatccagt gccatcccgg   1560

ttgcaggcgc cccactggtt actgcaacga ccactgcagt gtcttcagtc ctgctggccc   1620

caagtgtttt ccagcagaca gttacaagat cttcggacct tgagaggaaa gccagctccc   1680

cttctcctct aactattgga acgccagaaa gtcagagaaa gccttccatt attctcagca   1740

agtctcagct ccaggataca ttaatacatc taataaagaa tgattccagc ttcctcagta   1800

cacttcatga agtctacttg caggttctga ccaagaacaa agacaaccac aacctatgac   1860

tggagcagaa taagtctaaa ggcagagccc cagcctcaga gacaaatagg cttcatcatg   1920

gaaacttctg agcagaacat tgagtttgag aatcctgaaa ttgagcctat gagaaagaga   1980

ctcatttctt aagaatgttt tccaagtgac attctcagtg ataatggagg tttcactgtg   2040

aagcatcacc agcagatcct tgttttgaca aaaaaaaaaa aaaaaaaaaa aaaaaagaga   2100

gcgatcattg tgttaagtta tgtgggtgtt ttcatcagct aggagcaagg ctgtggaata   2160

aggagtcaga ttctcagctt gctttcactt tcaaggactt acagaggagt agtcaccagc   2220

ctcacagcag aagttcagcc cggcccccac cgcttccccc agcctacccc atagaaacgg   2280

gctttgggct gacaagtcaa gttttgaaca gagtagaagg cagctctgca aagtagcttc   2340

tagtttttag gaccagaatt taagccggca aattaggaat tatttcctca agtgaagtat   2400

attttatatg aatgccccat ttgggcctta aaagttgtga aatttcttaa tagcattttg   2460

tttttaagtg ccccagtcct gccctgcagc aggcccccag tgcagcatta ccatttgaat   2520

agggcactgt caggctctgg tggtgtggac acaggcatgt catacctttg aaggaaaggc   2580

tggggctggg aatgcccaca tcctatcaaa tcttcatttt aggttaaact ctccattggt   2640

tctgaaaatg ctaagtttgt gtgtgaagca cagccttatt ttccttttct gtcattgttg   2700

attgttttcc ttaacacttt gacaaaagga ccagtggacc aatctgacaa agccattctg   2760

gttcctttcc ttgagtgtac tgagaatagt tttaaagcta tgcagaaaag ggagctgtta   2820

ttcacactgc ccttattttg ttgtagaatt atggagttaa aagaaaatgt gattccgaac   2880

tctaccaatg tattcctagg ctgtgagtac tttcccggcc caaagtgtga aaatatgtaa   2940

agaagctttg ttatgctgct attgatctgc catgatttct atttattctt ttatggcatg   3000

taatggtgtt tagtaatatt ttaatgtaga ttttgattta tttcagcaat agtaatttta   3060

agatattctt tgaatgaaag tgtcttcgtt tctatgatac aggtcatttt gtagtattta   3120

accaattaag atgcactgct tacttttctg agcactattt aatgatgggg taaaaaccca   3180

attggctcaa ccagctagca taaggattag ctgtgaataa tgctgacaga tatgatggtt   3240

ccttaggaac aatcatttaa gctttaatgg taactcaatc ataagtccat agattatttt   3300

tttctagcta aaattttaga aaattacttg tgaattacat acttgtttta gtttggtctt   3360

agtttttagc ataaagaatg attggctttt gttgatctaa acatgcttcc tggacagggt   3420

ttctgcttct cattttagtg tcttctattg ctgtctacct aattatgtgt gaattgtgca   3480

gaattcaggg aagcttataa gttttcatgc tcaattgtga atagtttgtt ttcacagata   3540

gtatgtaaat taagcaacca aaaatgaatt ccttatgcat catctgggaa cgagaaagct   3600

atagtgggat acagagtgtt gctgacaccg ggagatggtg tccagggagc cacgtgactt   3660

ccataaagtg gacgcaccag taggtgtgat tgcacctcaa gtgtagtctc agtgggcttc   3720

ggtgaacaga cgaatcaagg gattcttgaa tcgaaattat gcttttgagt atgtaatatt   3780

atgagagagt taagagagaa tatcctaaag agagtctgtg atcatactaa ttttcacctt   3840

taatgctagg aatggatatg atagacagta aagagcatct atgataaggc ttccttagtg   3900

tgaaagtaaa cttaagtgcc caagtcatgg agacttgaaa agggtaaacc tgtttcacct   3960

cccaaattta tatattcaaa gtatttactt aaaattcaga agccagaagt tcatgtcatg   4020

attaccagga agttcaggcc agaatgaatc cctagagaag ccaggccaag cctggataat   4080

tgcagctgga tgaccctggc ccgaaagtca cagttcagtt gccttattcc tagttcaggc   4140

ttactatcta gaacctcatg ctagcttagg ttgcatgttt acattgctgc agtgtcttta   4200

ctggaagctt agttggatcg aaatggacac cgagatggag atgcttctgg ctagatttcg   4260

cagaacccca ggagacctgc atttagacca ctctgtccat ttgtgtgccc acccccaccc   4320

ccagggtcta agtgtagact ccaagaggag cagcccagag cttggaggag aggtgtgtct   4380

ggggcaccac tggtgggtgg tgctgctctt ctttttgttg tagttaatgc ggtgtctttt   4440

aatggactct caggcctccc agacagcctt gttcctttaa ggcagaagct cttcttcatt   4500

gtgtacctcc tgggattcat gaggtgtgag atttggcctg cttgactttg aattcaagtt   4560

tttcaagtga ctctcagtgt cagaagaagc atttcatgct gtccacatgt ggtatgtcca   4620

cagctcacct tcaaaggctt agatgtagcc atcacagaga gtggtatttt attaagaacc   4680

caagtcccag cctgaccaac atggtgaaac cccatctcta ctaaaaatac aaaaattagc   4740

cgggcgtggt ggcacgcgcc tatactccca gctacttagg aggctgaggc aggagaatca   4800

cttgaacccg ggaggcagag gttgcagtga gccaagatca caccactgca ctctagcctg   4860

ggcgacagtg agactccacc tcaaaaaaaa aaaaaaaaaa aaaaaaaaaa gtcacgctgg   4920

gcccctctct acagggggac acacaggctt agtttagtat atgtctaacc agattttgca   4980

tgtcaagcat ttgtcctttt cctggcttat gttttcttgt agaaattata taaaccctat   5040

caaatccact actaggtaaa tttttaaacc atgcagcttt attactctcc tcccccaaag   5100

aatgtagttt gaaattttct catttccata gtagaggccc taactgccat tgtattacta   5160

ataatgcaac atgaaattga aggtgcctaa ctgctcaaaa aacaaaatca gccatcatac   5220

tgtaactctg agaggaatga gaggtggcac aggcacgagt gggctcagcc cgtgtgagtg   5280

aggagaactg aggaatccta gggtgcgcat cctgcatcct ggctgcacgt ttgctgcaga   5340

gtatgttttt ctttcttgcc tcccttcagt tttcttcagt tgcgttcagt gtatcttctg   5400

gaaccaatag tgccctgtgt tctcaagtct ctaaaatgct aagatctgag caaagtcaag   5460

cagcttacac taggcttttt tacagctgtg cttgagaaca tttccgagtg gaccagggcc   5520

ttgaggagcc tgtttttcag caaattcaac agatgtgtgc agtgattccc tccgttttgt   5580

atttgacacc ttcatttaaa atgctaagat gcaatatcat tcacttcaaa gtggggaaaa   5640

tgcagaattg tgtttccttt ttatctgtgt gattccttaa gaaacatgtt tttaaaatat   5700

gtgttctaaa tggtttttta ttctgtatta ctgctttggc catgtggctc tcatgacttt   5760

cattgtacca gattctcagc tccctgaaac atggggacga gaagctctgg aattacagca   5820

agatttttgt tccatgagcg caatactgta tcattaacat ttttaatggt atggatttta   5880

tagcatctgt gtatgtttgc aaatattaag ttattacatg ttttaaaatg agcgtttttc   5940

atcttaaatt ttatatgttt gcaaatatat ttttttaata aaatttcaaa accaagtttt   6000

agcacctact aaaaaaaaaa aaaaa                                         6025


<210>  563
<211>  3422
<212>  DNA
<213>  Human

<400>  563
gtcccggcgg ccattgctcc aagatggcgg cggcggcggc agcgggagcg cagctcagct     60

gggctggaac tgccctcctg gaactccccc agcctacaac ctaggaggtg cagggactga    120

ggctcaggcc aaatcgcaac tcagacccag tgaacccaag gcctgaagag aatttggatt    180

catttacctt gttttgtggg gactggagag acaagtaaac tctcagagta actgtcccct    240

ctgactacca tttctaagga tgccccggag gcccagctag ccccagactt cggccccatg    300

cggctcaccc gctgccaggc tgccctggcg gccgccatca ccctcaacct tctggtcctc    360

ttctatgtct cgtggctgca gcaccagcct aggaattccc gggcccgggg gccccgtcgt    420

gcctctgctg ccggcccccg tgtcaccgtc ctggtgcggg agttcgaggc atttgacaac    480

gcggtgcccg agctggtaga ctccttcctg cagcaagacc cagcccagcc cgtggtggtg    540

gcagccgaca cgctccccta cccgcccctg gccctgcccc gcatccccaa cgtgcgtctg    600

gcgctgctcc agcccgccct ggaccggcca gccgcagcct cgcgcccgga gacctacgtg    660

gccaccgagt ttgtggccct agtacctgat ggggcgcggg ctgaggcacc tggcctgctg    720

gagcgcatgg tggaggcgct ccgcgcagga agcgcacgtc tggtggccgc cccggttgcc    780

acggccaacc ctgccaggtg cctggccctg aacgtcagcc tgcgagagtg gaccgcccgc    840

tatggcgcag cccccgccgc gccccgctgc gacgccctgg acggagatgc tgtggtgctc    900

ctgcgcgccc gcgacctctt caacctctcg gcgcccctgg cccggccggt gggcaccagc    960

ctctttctgc agaccgccct tcgcggctgg gcggtgcagc tgctggactt gaccttcgcc   1020

gcggcgcgcc agcccccgct ggccacggcc cacgcgcgct ggaaggctga gcgcgaggga   1080

cgcgctcggc gggcggcgct gctccgcgcg ctgggcatcc gcctagtgag ctgggaaggc   1140

gggcggctgg agtggttcgg ctgcaacaag gagaccacgc gctgcttcgg aaccgtggtg   1200

ggcgacacgc ccgcctacct ctacgaggag cgctggacgc ccccctgctg cctgcgcgcg   1260

ctgcgcgaga ccgcccgcta tgtggtgggc gtgctggagg ctgcgggcgt gcgctactgg   1320

ctcgagggcg gctcactgct gggggccgcc cgccacgggg acatcatccc atgggactac   1380

gacgtggacc tgggcatcta cttggaggac gtgggcaact gcgagcagct gcggggggca   1440

gaggccggct cggtggtgga tgagcgcggc ttcgtatggg agaaggcggt cgagggcgac   1500

tttttccgcg tgcagtacag cgaaagcaac cacttgcacg tggacctgtg gcccttctac   1560

ccccgcaatg gcgtcatgac caaggacacg tggctggacc accggcagga tgtggagttt   1620

cccgagcact tcctgcagcc gctggtgccc ctgccctttg ccggcttcgt ggcgcaggcg   1680

cctaacaact accgccgctt cctggagctc aagttcgggc ccggggtcat cgagaacccc   1740

cagtacccca acccggcact gctgagtctg acgggaagcg gctgaagccc tgataacctc   1800

gcctttgttt ttcgggggtc tgtctggatg tggagaagct ctgtgtgagc ggtgaggggt   1860

ggagggatgt cgcggagagg ggaaggggga aactgaccaa gaaagaaatt ctaaggagag   1920

catgagagaa ggctggcatt ggcaggagga gagcaccagg acgaggatgg gaagcgacct   1980

ccagatttat caaatggtca tgcccactgg gagccgtgga tatgcgtggg gacatcctgg   2040

gtcatctcag tcatggaggg agacggggat gtcacgccgt cccgcagggc ccagcacagc   2100

cccagacccg aaaaaagtgt tctgcccaag attccgagag ccctgcgctc tagggcaggg   2160

gcagagtttt ggaaacagtg caggctctgg agccagactg gcgagattca aatcctggct   2220

ctatcgcttc ggagccaggt gggcctgggg gggcgtcgca gtctctctgt gcctcagttg   2280

cttccaggat gcgggaccct tggctgcagg ggttgcttcc gccactagag ggcgcgccgg   2340

tcccgctcct ggtggcccac tgtggctgcc cgggcgacag tacgcccagg gcctgtgttc   2400

catagccatc tactctcttg agcctttgga cttctctcca agcccctgtg ggaggcggac   2460

agcagtgacc acctcccctt cttttggact gcgacctcct tccctcctgg gagagccctg   2520

tgacctgcat gctactctta actgttctat tcaagactga atagaagtat ttcagtcttg   2580

cagaggagga aatgctcaga gctccgaggt gcggctgtgg tcgagaaccg ggtgctgggc   2640

cgggcgcggg ggctcacgcc tgtaatccca gcactttggg aggccgaggt gggaggatcg   2700

cttgagccca ggagtctgag accagcctcg gcaacatgcc aagaccccgt ctctattttt   2760

aaaaaagaaa aagaaccgac ttctgaatcg cagctccact catgactaat acctcattat   2820

ttcagctgtc tgcacctaat tccccacttg cacggcagtg tagacaataa ccatagctca   2880

cactcactga gcacctactg ggtaccaggc accattctca gtgtttcacc tggatcaact   2940

aatgcgtccc tcacctcagc cctctgaagt gacagctgct attattttca ttacacagat   3000

gaaaaagctg aggccagaat cgtgaagtca cttgctcaag gtcaggcagc ttaggaaggg   3060

gcagatcggg ggcttgaacc caggtggtca ggctctggag cccacaattg tcttacccac   3120

tatgcccctc tctagtcatg gtccccaaga ggggcttgga gacccactta gcaggtgaaa   3180

gcaatggcag ccttccttat ttgattatgc acctaagaat aaatggtatt tgggcatgta   3240

ttcccaatat gtgtatattt atttataaat atatacagat actattatct gtatgttagt   3300

aataaagctt aaattattcc attttaaaat tatgaatatg aatagggttt tttttatgtt   3360

tcttgcctca tcccaatgac ttttgcacac ccaggtgtga gcacccagca ttcaagacca   3420

cg                                                                  3422


<210>  564
<211>  2548
<212>  DNA
<213>  Human

<400>  564
attccacagc ggccgcaacg tgtcgagagc cgtaagtaaa gtgtcgcaaa gcagaaggaa     60

ggcgggagtc ccgactgcaa acattgagga aagccaggca gtagaggccg ctatggcgaa    120

cgttccgtgg gcagaggtct gcgagaaatt ccaggcggcg ctcgctctgt cgcgggtgga    180

actgcataaa aatccggaga aggaaccata caagtccaaa tacagcgccc gggcgctact    240

ggaagaggtc aaggcgctgc tcggccctgc gcctgaggac gaggatgagc ggcctgaggc    300

cgaggacggc ccgggtgccg gtgaccacgc cctggggctg ccggctgagg tggtggagcc    360

cgaggggccc gtcgcccagc gagcggtgag gctggcagtc atcgagttcc acctcggggt    420

gaaccacatc gacacggagg agctgtcggc gggggaggag cacctggtga aatgcctgcg    480

gctgctgcgc aggtaccggc tctcgcacga ctgcatctct ctctgcatcc aggcgcagaa    540

taacctgggt atcttgtggt ctgaaagaga agaaattgaa actgcacagg cttacctaga    600

gtcatcagaa gcactatata atcagtatat gaaagaggtt gggagtcctc ctcttgatcc    660

tactgagcgt tttcttcctg aagaagagaa acttactgaa caagagagat caaaaagatt    720

tgaaaaggtt tatactcata acctatatta cctagctcaa gtctaccagc atctggaaat    780

gtttgagaag gctgctcact attgccatag tacactaaaa cgccagcttg agcacaatgc    840

ctaccatcct atagagtggg ctatcaatgc tgctaccttg tcacagtttt acatcaataa    900

gctatgcttt atggaggcca ggcactgttt atcagctgct aatgtcattt ttggtcaaac    960

tggaaagatc tcagccacag aagacactcc tgaagctgaa ggagaagtgc cagagcttta   1020

tcatcaaaga aagggggaaa tagcaaggtg ctggatcaaa tactgtttga ctctcatgca   1080

gaatgcccaa ctctccatgc aggacaacat aggagagctt gatcttgata aacagtctga   1140

acttagagct ttaaggaaaa aagaactaga tgaggaggaa agcattcgga aaaaagctgt   1200

gcagtttgga accggtgaac tgtgtgatgc catctctgca gtagaagaga aagtgagcta   1260

cttgagacct ttagattttg aagaagccag agaacttttc ttattgggtc agcactatgt   1320

ctttgaggca aaagagttct ttcagattga tggttatgtc actgaccata ttgaagttgt   1380

ccaagaccac agtgctctgt ttaaggtgct tgcattcttt gaaactgaca tggagagacg   1440

gtgcaagatg cataaacgca gaatagccat gctagagccc ctaactgtag acctgaatcc   1500

acagtattat ctgttggtca acagacagat ccagtttgaa attgcacatg cttactatga   1560

tatgatggat ttgaaggttg ccattgctga caggctaagg gatcctgatt cacacattgt   1620

aaaaaaaata aataatctta ataagtcagc actgaagtac taccagctct tcttagactc   1680

cctgagagac ccaaataaag tattccctga gcatataggg gaagatgttc ttcgccctgc   1740

catgttagct aagtttcgag ttgcccgtct ctatggcaaa atcattactg cagatcccaa   1800

gaaagagctg gaaaatttgg caacatcatt ggaacattac aaatttattg ttgattactg   1860

tgaaaagcat cctgaggccg cccaggaaat agaagttgag ctagaactta gtaaagagat   1920

ggttagtctt ctcccaacaa aaatggagag attcagaacc aagatggccc tgacttaatc   1980

cttgttttta aagaaaggaa atgtgcaata ttgaagtgat ctttttccct agtcagacag   2040

gcccaattcc attgtgatgt ttacctttat agccaggtga gtgcagtttg aacttgagat   2100

acagtcaact gagtgtttgc taggatccta aggaacataa agttaattaa aaacttacac   2160

ctaattatgt aaattgcctt gttaaagaca tgtgatttgt attttagatg cttgtttcct   2220

attaaaatac agacatttct accctcagtt tctaaatgta gactatttgt tggctagtac   2280

ttgatagatt ccttgtaaga aaaaatgctg ggtaatgtac ctggtaacaa gcctgttaat   2340

atattaagat tgaaaaagta acttctatag ttactccttc taaaatattt gacttcctaa   2400

attcccccca cccaaaatct ttcccttttg aaaatactaa aaactaagtt atgttattat   2460

aaagtgtaaa atggtttgtc ttaattatag gagaaaaagg ccttgttaga aataaaataa   2520

actgacttat ttcactaatg aaaacaaa                                      2548


<210>  565
<211>  9300
<212>  DNA
<213>  Human

<400>  565
gcggggcggg tcgcgctggt ccccggccgg ccggagcggc ggcggtggcg gcgcgaggcg     60

gcatgaggga gccgctcgtg ctgggtcctg ccaccaccat ggttccagtg gttgagcttt    120

gctgaagccc aggcatcatg tacagtgtag aagacctcct gatctctcat ggatacaagc    180

tgtcaagaga ccccccagca tcacgcgagg ataaccccaa ggggcgccag gcagcgagga    240

ctgggacacg agcaggccag ggcctgcaga acgggcatga ggatggccct gcggccctcg    300

cacatcgtaa gacgtccgcg gggaaaggac atgtgagtga ctccgaaagc cgccgcagca    360

caccgagagg ccacggggag ccccagagca cttctgcttc cagaacctcg gaggcggggt    420

tttgtaatca acccccctca gcatggtcct ctcatccccc gactggtaac gaccaagcct    480

accggagaag aggacggcaa gaagccagga gccagaagcc gagggagcac gaaaacctgg    540

aggccagagg aatggcccaa gcccacagcc tgcctgtcca cgtgagggag ggtccatggg    600

aagttggagg aaggtcagag catgtgatga agaagccagt ttgggaagaa gaattgcgaa    660

tgtcaggtcc tgccaagtgg cagaacgtca gcctggaaag ctggaaccag ccaaggaaat    720

tagggaggca gatgtctgat ggagatgggg agagactgtt tcaagacctg tacccattca    780

ttcaaggaga acatgtgttg aattctcaaa acaaagggaa gtctcgctca ctgcctagag    840

ttctttcccc cgagagcctg agttgcacgg aaattcccat tccattaaat gaaagacatt    900

cacctaaaat gccaccgtat cctcccactt gcgcaccaaa tttggactcc acgaggaatt    960

ctgagaagag tggctgctca gccccatttc cccggcctaa gtttgggagg cccctcaagc   1020

ccccatctta cagctcgcac cagcagtcta ggggaggagc ggacagcagt gactctcagg   1080

acagccagca gatggacgcc tatgtcccca ggcatgagct ctgcctgtca gaccctggat   1140

tggaacctcc agtgtacgtg cctccgccct catacagatc gcccccgcag aacatcccaa   1200

acccctactt ggaagacacg gtgcccataa atgtgtgtgg cggtcacagt caacagcagt   1260

ctccgaccga gaaggctggg gccagcggtc agcctccttc aggcccccct ggaactggga   1320

atgagtatgg tgtgagcccc cgcttgcctc aggggctccc cgcacatccc cgacctgtca   1380

ctgcctatga cggcttcgtt cagtacattc cctttgatga tccacggtta cgacatttta   1440

aactagctca gccccagggt ttctgtgaag acataaagct tgacgataaa tcatataact   1500

ccagtcctgt cactgctcaa gagccggctc atggaggaat gcagcctgat ggtgccattt   1560

ggaatccaca gagcttaata cccccgtcgg gggatgagag aggcctggtc ttggccgatt   1620

ccagcccccg gtggctgtgg ggccagcccc ccggggatgg ggaaaacagt ggcctcccca   1680

accagagaga ccgctgtgtg gcaaggggac agtggcctga tgtgagaggc agccagcacg   1740

ggcacactgg aagacaagtt tcctcccctt actcacaggg cgagagcacc tgcgaaactc   1800

aaaccaagct caaaaagttc caaactggga ctcggaccaa gaaaagttca aagaaaaaaa   1860

tgaacgagac tatattttgc ttggtttcta tcccagtgaa atcagaatca catctgccag   1920

atagagatat ggacaacaat gacttaaagc ccagtgctga tcaaaagaat gggtctgata   1980

agagcccggc tctgcaagaa cagagtctgc tgagcatgtc ttccaccgac ctggagctgc   2040

aggccctcac aggaagcatg ggtgggagaa cggagttcca aaaacaagat ctaggggaac   2100

cagaagaaga cagacaaaca aatgacctca gtttcatcca ccttacaaag cacagagaac   2160

tcaagcattc tggctcttgg ccagggcacc ggtacagaga tcagcaaaca caaaccagtt   2220

tctccgagga gccccaaagt tcgcagctgc tccctggtgc aaagctggga gggccgagtc   2280

gtgcagcatt gagtccaaaa tgttcagacc ctgctgcctc cgaagctcag acgcacacag   2340

cattccctac cggtgatcac aaacagaggc caagtgcccg taacctgaaa ggtcacaggt   2400

ccctcagccc atccagcaac agtgcgttct caaggacttc cttgtccgtg gaccaggcac   2460

cgacgccaaa agcaggccga agtcagccct gcgtggatgt ccacgggctt ggagcccacc   2520

ctgggcctaa gcgggaggtg gtgaaggggg agcccacggg cccttgcaac agtaaacaac   2580

tctttgggca gtttctcctg aaaccggtca gccgtcgtcc ctgggatttg atcagtcagt   2640

tagaaagttt taacaaggag ctccaggaag aggaagaaag cagcagtagc agcagcagca   2700

gcagcagcag cagtgaggag agtgaggcgg agccgcagca ggagaaccgt gctcactgca   2760

gacaggagga tgtgggcttc cgcggaaaca gcccggaaat gagggttgag ccacagccga   2820

ggatgtgggt gccggagagc cctgtgtgta ggtcgggaag aggtgagagt aagtctgaga   2880

gctggagtga ggagctgcag cctggccacc cacgtgcctg gcctccatcc ccgggccgct   2940

ttcgcgtgga agaaggtggc ggtgcacctt tctgctcagc agatggaagc acgagtgcag   3000

agaagagaca cctggaggtt agcaacggaa tggacgagct ggcaggtagc ccatttcctg   3060

tgacgagaat gtcttcaaga tcaagtgacg caaaaccact gcccgcgtcc tatccagctg   3120

aacctaggga gccccaggaa agtccgaaaa tcaccagtgc tttcagctct gtgaaaccaa   3180

gtgaagcggt ccctcggaag tttgacagtg gtggagagag gggggcaggg ctcccactgt   3240

ccctgtctaa caagaaccga gggctctcag ctccagactt acggtctgtg gggctcaccc   3300

ctgggcaaga acagggtgcc agtgagctag aggggtcttt gggtgaagca agcacaatag   3360

aaatcccccc aggtgagtcc ttgcaagcca gggctgcaag gatcctgggc attgaggtgg   3420

cggtggagtc cctcctgccg ggcatccgga gagcgggaca gaaccagcct gctgagcccg   3480

atgcaagtgc ctgcacccca gagtcccccc aggaagagtt gctatctcgc ccagcaccgg   3540

cagatgtccc cagggtgtcc actgatgcct tttatggcag gaggaagtgc ggctggacca   3600

agagccctct ctttgtaggg gacagggaca gtgccaggcg ggctcctcag gcttttgagc   3660

actcagatgt ggacggggtt gtcaccagca cagaccctgt ccctgagcct gagcccagcc   3720

ccttggagtc caagttcttc gaacaaaagg atgtggaaac aaaaccaccc ttcaggtcca   3780

ctttattcca ttttgtagaa agaaccccaa gtgtggcagg ctctgaaaag agacttagaa   3840

gcccttccaa agtgattgaa agtttacaag agaaactggc ctccccgcct aggagagcag   3900

accctgaccg cctgatgaga atgaaagagg tgagctcagt gtcacggatg agagtcctga   3960

gcttcaggaa tgccgactcc caggaggacg ccgaggaatt gaaggccacc acaaggggcc   4020

aggccgggct cccgggaggc cttgtgtctc ctggcagtgg ggaccgtgcc cagagattgg   4080

gccactcact ctctgtgtcc aaggacagca tctccaggga agagaaggag catccggcag   4140

cacaaaagga gaagagcatg gatcaagact tctggtgccc agattcctat gaccctagca   4200

gagtggagag ggtgtgatga aatgccggtg gagcttgcat tccgttgcga attgagtatt   4260

ctcaagtagc tggtagattt agtctatcag ccccacttcc ccatgtagaa gctggaagct   4320

gctgagtttt tagcatcctg ataacattct ttaccactgc cactaggaaa cttgccatcc   4380

tctcagaatt gctttgtggc gataaagcaa tcgtccgttg aaaccatctg tttttatagc   4440

atgaagattt aatgcctata attaggaagg agttttcaca gaaaccctcc ctcatgacag   4500

atttgactaa gctggtaaat agtttggtgt tgctctcatt ctgggtgaag atttcaatgt   4560

ggaagatcta gcaaatgctt tggaaaggcc tgtgaatggt gtgctcccct ctgtgtctcc   4620

atggcctgca gtccatgctc ttgtgaagga gtttgggaca ctggctgttg cccggtgttt   4680

cagcactttc agtttagggg aaatgtgaat caataggtat gatccatttc taatcaattt   4740

ggccttctgc tgctggaagt aactttactt ataagtaact tgccatcaga gaataaaagc   4800

aatatctttt aagttcctga aaaattaaaa cttgtactgt aatatactaa gagtattatt   4860

tatctggcag tgaaatattt tgatcatttg caaacacgcc attgtctgct ttgcactcag   4920

tattatctat ttttattttc tgtatgggta tttagaaatt ctttatatga aaaataattg   4980

ctggtttaaa atagaccatt ttaacaaagt gactatattt ctttttacga aaatgctatt   5040

tttctatgat gtaaacaatt gttaggcggc agatttttaa ggaagtatta ttttatttaa   5100

gagtctgtat ccctttgtgt gagaggaacc caaagagggt tcacttttgc tttaaagctc   5160

tgtcccttac ccactgacaa ctctgctact tttattttat cttagaaaat gtcaatatag   5220

acatatcaca gggttaataa aagaaacttt tcacaaagat ttttgtacaa gtgtagctat   5280

caggttatat ttgaaaataa ccctctgaaa accagccaac attgtcatga caatttttgc   5340

tgccgtatca actagaatta ccaaaaaaca tagttttatc tttgtatgtg tgtggggatc   5400

taccctgaga ccatgctttt cttcccaccc tgccacccca cccctttaaa gaaatacgta   5460

tttttatcta gaatgatctt gaattagtct ctgcatattt ttagaaagtg cttggggaca   5520

ttatatatat gccattacaa aagcattatg aggcctatgt attctactgt gtttaatact   5580

gcattaacct gcacaaagtt tatgcatttt ttcatgcatt tttttccttc tttctaagta   5640

aggtattcct gacaactaac attccctaaa tcatttcccc tccctccctc cctccctccc   5700

ttcctttctt ccttccttct gtcctccctc ccttgctacc tcttgccctc cttccttcac   5760

cctgtcctcc ttttcccttt tattttttcc ccttctcttt cattttattt tcttttagag   5820

aaaccacctt atctattttt agacatttcg aattcctaaa atgtgaaccg ttgggtgatc   5880

tgtcctttgg ccctaaaacg gctggccggg ctgtcccggc ctgttctcat ctgtaccgta   5940

tgattttatt tcataataac tttatgtatt tggactgtaa caaacaaaac agaacctaag   6000

tcgccccgaa aaatctttcc aagccttttc aaaacactta tctgcagtcc agaattcagc   6060

tcttatgaaa agtgagagtg cactccagtt ttcacagcag caataagtgc gggaaacaaa   6120

aagatcctct tcccaggaaa agttgagtgg ggaagagttc agacactgtt gtagctggtg   6180

aatcattgaa gtcacctggt agtaccaaat aagggctgag gcgcctggag gtctttgtgg   6240

ggtcttccct ctttaaatgc aaacgtaaga aggtatatgt gtatatacat ttatatacgt   6300

gcacatgtat actcgtacat gtatgcacac atacccatac atgtatatga actccgttct   6360

gatttcctct gaaattttgt tgataccatc taaatacctc tttgaatcaa aataacttaa   6420

ttttagctca ttcctcaaga gaaagagaag gatccccaag gaagaaaaac tgttgtacct   6480

tctgtgattc tcaaaccaaa atgtgatgcg cttctgtttt gttatcttaa attgttgtat   6540

catatctttc tgaaaccatt ctgaattaag ttgaaatttt caacatttat actttaactg   6600

ttctaaattt aagcctacat gtaaatcttt tttgggggga aggtaacttg aaaagtttaa   6660

cttgaaaatt tgacctttaa actttcatat tctaaggtaa ataatagcct ataaccaaca   6720

acagctttcc cagaggtctt gaatttaaca ctaattgttt agttattgtt tctatttctc   6780

atacatacat aacttcgttt tttgtggctg gaagaaaaag tttctatatt ttgtatttgt   6840

ctttgttctt ctcatgcaca caatttactg ttggtgttta ataatttgga gctcataaaa   6900

ttaaaagttg taattttgac catttgggct aaaaattata tgagggatta catatgcaat   6960

ggattagtat ttcttgattt gcaaaagaag ggaaaatgat ggtaatttag ctcaaattgc   7020

ctttctttga agaaaatttc tgaatgactg aaaaccaaat atctatatta tcactttcaa   7080

cctcatgttt ctgcaaagta cagaaaaact cctcactgac agtgcaccca gcccctgact   7140

gggttttcag gattatgtcc atgtgcataa ctgcttggat ttcttctttt aaagtcccta   7200

aaacatgaat ctgttctttg agatcctggt ttccttagca gagttgtagg ttgcgggttt   7260

cattcacgtg gaaattctaa gtagaacttt tgctgcccca ttttactgtt ggtgaagggc   7320

cgttgttaat ggaagtttac gttttaaaac tcagatgact cagaaaccag actgtgatca   7380

ttttttgcag cagcaaaatg acttattctg acagcatctc ggtttggggc ttctgaagaa   7440

aaaggatgaa gctgatctgt tgaaacaact actttcccaa ctcggaggca aaaggggctg   7500

atagaagata acattcacct accatttcat cttgtgaccc ccagagatca cgtttgcgtg   7560

ttctggctga gttttttatt attgtttgtt ttaaatgatt aaataataca caattaaatg   7620

tcaggatagc atctcttgca aagtgaccag tgcagcagaa ttgtctttct atccatattt   7680

gagcttagag aaacatttcc catgtcctaa gttcttagaa gcaattactt tagcgttggg   7740

gagcattgtt ctaccagacc catttatgca ggggagatga agcttaaaag acgggatgtg   7800

gggtgggagt gtgtttctta agccgaagct gttgcaggct gggggatttt tgcattttct   7860

ttttgttttg tttttgactg cagattctgt acatctgtct gtgggaggag agttgctact   7920

caggacagga tttaagagac acattccagt gacctttaag aatctgcatg gcgggaggtc   7980

cttctccagg agtgtgggtt ggtccactct gggacccacc acactaagaa gggggagatg   8040

ataaaataac attaaaggaa gaatggcctc cagcctgcag gttttgttgg aaagaaataa   8100

aaagggagtc attaagacca taaattcaga ttgaggcctc ttgaaaaggt tgatgtgggc   8160

tagcaacctg cctgtcgaaa cagtccttgg ttcatcagca gtgtgggaag gcagccaagg   8220

ctcctgcaga ttcctggcat cgaccttgga aagcctctgc gatacttgtg tgtacgaata   8280

cagcagagga cagggaggtc cttgttctgt ggtctctgtt tagtgactga aacttaaacc   8340

caaaggcaag cccagattgt ctggccgttc atccccatgc tttgataggg gttaggagga   8400

accctttccg tatgaaagac aggccctact agggcttaca accaagccaa aggaccatct   8460

cttctttctt ccacctccct tcacccctgc cccgcagcag agccgagatg tgagacattc   8520

attgtcacgg agcaaggaga caaaggcaag ttcaagttga gaagcatatg gcagcaaaca   8580

gaaatgaaaa ccatatgtcc cagcaagggg aaaagcagtc atttccagat tataaaaatc   8640

aatgaagtac tctccaccta ggtcagctga aattcgagcc ctcacagtca ggcctgtcag   8700

agaagttaag cagaaacatc tcggggggac ttctaaaatt tagtgaagac aaggccttgc   8760

aactccaaag aaactttttt tccccccctt gaaacagggt cttgctctgt tgcccagcct   8820

ggagtgcagt ggtgcagtca cggctcactg cagcctcaag ctcctgggct caagcactat   8880

ccccacctca acctccttag tagctgggac tacaggtgca caccaccatg cccagctaac   8940

cacagaaact ttcatctctt cattttttct ttgggcacca ttaataccta agacaggtag   9000

aaagggtccc agaaagacac cattggtaat ggccgattgc cggctgcagt catcgccccc   9060

agatcaggct ggtacaggat gccttaaggt gatgagaggt gagggtgcat gaagaataat   9120

gagcacaggg aagagagaag caggacaaag tagcagataa aatgccggca aagcacagat   9180

gaatgtcttc aagaagctct tgtatttctc tgcacagtgt aaatatcctt gctatttcag   9240

gatggcggct ggcctgctca gtaacataca tgttccaaat aaagattttg catgaaagta   9300


<210>  566
<211>  2115
<212>  DNA
<213>  Human

<400>  566
agttccaggt accgccactg ggggcggccg cggcctcccc agcggcaacg gccacgaagc     60

tgcgcggccc tggtttccag ccgggccctt ttcgcggccg ggccccagca tggctgcccc    120

cacggctgag ggcctggcag ctgctgcgcc ctcgctttct tgacattccc tggcttctgt    180

gctctcttcc ccaggccacc ccagcagaca tgtttgccaa ggcctttcgg gtcaagtcca    240

acacggccat caaggggtcg gacaggagaa agcttcgagc tgatgtgaca actgctttcc    300

ccacccttgg aactgatcaa gtctctgagt tagtacctgg aaaggaggag ctcaacattg    360

tgaagttgta tgctcacaaa ggggatgcag tgactgtgta cgtgagtggt ggtaacccca    420

tcctctttga actggagaaa aatctgtatc caacagtgta cacgctgtgg tcctatcctg    480

atcttctgcc aacctttaca acatggcctc tggtgctcga gaaactggta gggggagcag    540

atttgatgct gcctggactg gtgatgcccc ctgctggtct gcctcaggta cagaagggcg    600

acctctgtgc catttctttg gtggggaaca gagcccctgt agccattgga gttgcagcca    660

tgtccacagc tgagatgctc acgtcaggcc tgaagggaag gggcttctct gtgctccaca    720

cttaccagga ccacttgtgg cggtctggaa acaagtcctc tccaccttcc attgctccac    780

tggccctgga ttcagcagat ctcagtgaag agaaggggtc tgtccagatg gactccaccc    840

tgcagggaga catgaggcac atgaccctgg agggggaaga ggagaatggg gaggttcacc    900

aggcacgtga agacaagtct ctctcagaag ccccagaaga caccagcacc aggggcctga    960

accaagactc cacagatagc aaaacgcttc aagaacaaat ggatgagctg ttacagcaat   1020

gcttcttaca tgccttgaag tgccgagtca aaaaggctga cctcccttta ctcaccagca   1080

ctttccttgg cagccacatg ttctcctgct gccccgaagg acgacaactg gacataaaga   1140

agtcaagcta caaaaagctc tctaagttcc tgcagcaaat gcagcaggag cagattatac   1200

aggtgaagga gctgagcaaa ggggtggaga gcattgtggc tgtggactgg aaacacccga   1260

ggattacatc tttcgtcata cccgagccct ccccgacctc ccagactatc caggagggta   1320

gcagggaaca gccctatcac cctccagata taaaacccct ctactgtgtc ccagccagca   1380

tgaccctgct cttccaggag tctggccaca agaaggggag ctttctggag ggcagtgagg   1440

tccgaacgat cgtcattaac tacgccaaga aaaatgacct ggttgatgca gacaacaaaa   1500

atcttgtgag attggatccc atcctatgtg actgcatctt agagaaaaat gaacagcata   1560

cagtcatgaa gcttccatgg gacagtcttc tgaccaggtg tttggaaaaa ttacagcctg   1620

cctatcaagt gacccttccc ggacaagagc ccattgtgaa gaaagggaga atctgtccaa   1680

ttgacatcac cctagcacaa agagcgtcta ataaaaaggt gaccgtggtc cggaacttgg   1740

aggcctatgg tctggaccca tactcagtgg ctgccatcct tcagcagcga tgccaggcta   1800

gcaccaccgt caatcctgcc cctggggcca aggacagcct tcaggtgcag atccagggaa   1860

accaggtcca ccacctcggc tggctattgc ttgaagagta tcagctccct cgaaaacaca   1920

tccaaggtct agaaaaggcc ctcaaacctg gcaagaagaa gtgacagact cttttgtctc   1980

acgtggtgga tccggtggaa atccaagctc tgggctggta atttttatga gcattttcag   2040

cttttgcaaa tacaaaatat aattctttac aaaaataaat ttttattcta atctaaaaaa   2100

aaaaaaaaaa aaaaa                                                    2115


<210>  567
<211>  1234
<212>  DNA
<213>  Human

<400>  567
aaagacttcc ggtcggcgtg agcgtgaggt gtgggtgttc gtttctcagg taaaacatgg     60

ctaaaagctt acggagtaag tggaaaagaa agatgcgtgc tgaaaagaga aaaaagaatg    120

ccccaaagga ggccagcagg cttaaaagta ttctcaaact agacggtgat gttttaatga    180

aagatgttca agagatagca actgtggtgg tacccaaacc caaacattgc caagagaaaa    240

tgcaatgtga ggtaaaagat gaaaaagatg acatgaaaat ggagactgat attaagagaa    300

acaaaaagac tcttctagac cagcatggac agtacccaat atggatgaac caaaggcaaa    360

gaaaaaggct gaaggcaaag cgagagaaaa gaaaggggaa aagcaaagca aaagcagtga    420

aagtggcaaa gggtttggcc tggtagactc ttaaaacctt ggaaaatgcc acatgggata    480

gatgacggat tagaatgtat acacatgtat actttgattt caactgccac caaatgaaaa    540

ccatttgttt tcctatttta acttggcctt ttttcttcaa ttcaaaccca gcataactcc    600

tcaagtttgt tttgggaact tgaataaaat attttctttg atacatccaa gctctactga    660

tactttaact ggatgctacc caatatccag ttataatcag gcctcaacgt tctgtcaggt    720

attaatatgg ttagaattgt tcttacaact ggtaattata gtcaatagag ataaaacaga    780

tgatgtactg acaaattttt gtgaacttag attttaaaga aagttgttgt ataatcatat    840

catttaaaaa tactacatta gggctgggca tggtggctca cacctgtaat cccagcactt    900

tgggaggccg aggcaggtgg atcacgaggt cagttcgaga ctagcctggc taatacagtg    960

aaaccccatc tctactaaaa atacaaaatt agccgggcat gggggcgcgc acctgtagtt   1020

ccagctactc gggaggctga ggcaggataa ttgcttgaac ccaggagatg gaggttgcag   1080

tgagccaaga ttgccccact gcactccacc ctgggcaatg gagtaggact ctgtctcaaa   1140

aaaaaaaaaa ataatggatc ttataaagta cttgtgtgga gctttgattc cacagaataa   1200

aagatatttt gtgtgtaaaa aaaaaaaaaa aaaa                               1234


<210>  568
<211>  7265
<212>  DNA
<213>  Human

<400>  568
gggccgtcgc caccactgta gtcatgtacc caccgccgcc gccgccgcct catcgggact     60

tcatctcggt gacgctgagc tttggcgaga gctatgacaa cagcaagagt tggcggcggc    120

gctcgtgctg gaggaaatgg aagcaactgt cgagattgca gcggaatatg attctcttcc    180

tccttgcctt tctgcttttc tgtggactcc tcttctacat caacttggct gaccattgga    240

aagctccagg aggcatatat ggcaacgaat tggcaagaaa tcaagataaa gagaaaggta    300

gagctgtatg taaccacctg gctagaacac agatgttaat ttgatgctgt ctgactactt    360

tctaggtctc tggtctctgg ctttcaggct agaggaagag cagaagatga ggccagaaat    420

tgctgggtta aaaccagcaa atccacccgt cttaccagct cctcagaagg cggacaccga    480

ccctgagaac ttacctgaga tttcgtcaca gaagacacaa agacacatcc agcggggacc    540

acctcacctg cagattagac ccccaagcca agacctgaag gatgggaccc aggaggaggc    600

cacaaaaagg caagaagccc ctgtggatcc ccgcccggaa ggagatccgc agaggacagt    660

catcagctgg aggggagcgg tgatcgagcc tgagcagggc accgagctcc cttcaagaag    720

agcagaagtg cccaccaagc ctcccctgcc accggccagg acacagggca caccagtgca    780

tctgaactat cgccagaagg gcgtgattga cgtcttcctg catgcatgga aaggataccg    840

caagtttgca tggggccatg acgagctgaa gcctgtgtcc aggtccttca gtgagtggtt    900

tggcctcggt ctcacactga tcgacgcgct ggacaccatg tggatcttgg gtctgaggaa    960

agaatttgag gaagccagga agtgggtgtc gaagaagtta cactttgaaa aggacgtgga   1020

cgtcaacctg tttgagagca cgatccgcat cctggggggg ctcctgagtg cctaccacct   1080

gtctggggac agcctcttcc tgaggaaagc tgaggatttt ggaaatcggc taatgcctgc   1140

cttcagaaca ccatccaaga ttccttactc ggatgtgaac atcggtactg gagttgccca   1200

cccgccacgg tggacctccg acagcactgt ggccgaggtg accagcattc agctggagtt   1260

ccgggagctc tcccgtctca caggggataa gaagtttcag gtaagggggc aggctttctg   1320

gctggatgcg cctcccctgg agctaccttt tgctcatcac agcaggtact gtgtgtgtgt   1380

gtgtatgtgc atgtgtgttt tcaggttttt tactgtgata aaacacacaa aacgcaccac   1440

cttaaccatt tccaggcgtg gtcggtggtg ttacattcac gctgttgcag gcgtgcaggt   1500

cggtggtgtt acacacattc acactgttgc aggcgtgcag gtcggtggtg ttacacacat   1560

ttgggctgtt gcaggcgtac aggtcagtgg tgttacacac atgctgttgc aggagtacag   1620

gtcggtggtg ttacacacat tcatgctgtt gcaggcgtgc aggttggtgc tgttacacac   1680

atgctgttgc aggagtacag gtcggtggtg ttacatgctg ttgcaggcgt gcaggtcggt   1740

ggtgttacat tcacgctgtt gcaggcgtgc aggtcggtgc tgttacacac attcctgctg   1800

ttgcaggagt acaggtcggt ggtgttacac gtgctgttgc aggtgtgcag gtcggtggtg   1860

gtacacacat tcatgctgtt gcaggagtat aggtcggtgg tgttacacac attcacgctg   1920

ttgcagacgt gcaggtcggt gctgttacac acattcatgc tgttgcagga gtacaggtcg   1980

gtggtgttac atgctgttgc aggcgtgcag gtcggtggtt acattcacac tgttgcaggc   2040

gtgcaggttg gtgttacaca cattcacagt tgcaggcgtg caggtcagtg gtgttacaca   2100

ctcacacttg caggcgtgca ggtcggtggt gttacacaca tgctgttgca ggcgtgcagg   2160

tcggtggtgt tacacacatt cactgttgca ggcgtgcagg tcggtggtgt tacacattca   2220

cgctgttgca ggcgtgcagg tcggtggtgt tacattcacg ctgttgcaga cgtgcaggtc   2280

agtgctgtta cacacgctgt tgcaggcgtg caggttggtg gtgttacatt cacactgttg   2340

caggcgtgca ggtcggtggt gttacacaca ttcattctgt tgcaggcgtg caggtcagtg   2400

ttacacacat tcacgctgtt gcaggcgtgc aggtcggtgg tgttacacac attcacgctg   2460

ttgcagatgt gcaggtcggt gctgttacat tcacgctgtt gcaagcgtgc aggtcggtgg   2520

tgttacattc acgctgttgc tggcgtgcag gtcggtggtg ttacacacat tcacactgtt   2580

gcagacatgc aggtcggtgc tgttacacac attcatgctg ttgcaggcgt gcaggtcggt   2640

ggtgttacat tcacacttgc aggcgtgcag gtcggtggtg ttacacacat tcatgctgtt   2700

gcaggcgtgc aggtcggtgg tgttacacac attcacactg ttgcaggcgt gcaggtcggt   2760

ggtgttacat tcatgctgtt gcaggcgtgc aggtcagtgg tgttacacac attcacgctg   2820

ttgcaggcat gcaggtcggt ggtgttacac acattcacgc ttttgcaggc gtgcaggtcg   2880

gtggtcttac attcatactg ttgcaggcgt gcaggtcggt ggtgttacat tcacactgtt   2940

gcaggcgtgc aggttggtgt tacacacatt cacacttgca ggcgtgcagg tcggtggtgt   3000

tacacacatg ctgttgcagg cgtgcaggtc ggtggtgtta cattcacact gttgcaggcg   3060

tgcaggtcgg tggtacacac attcacactg ttgcaggcgt gcaggtcggt ggtgttacac   3120

acattcatgg tgttgcaggc gtgcaggtcg gtgttacaca catgctgttg caggcgtgca   3180

ggtcggtggt acattcatgc tgttgtaggc gtgcaggtcg gtggtgttac acattttcac   3240

gctgttgcag acgtgcaggt cagtggtgtt acattcatgc tgttgcaggc gtgcaggtcg   3300

gtggtgttac attcacgctg gtgcaggcat gcaggtcggt ggtgttacac acaacgctgt   3360

tgcaggcgtg caggtcagtg gtacacacat tcacgctatt gcaggcgtgc aggccggtgg   3420

tgttacattc acgctgttgc aggcgtgcag gttggtgtta cacacattca cacttgcagg   3480

cgtgcgggtc ggtggtgtta cacacattca tgctgttgca ggcgtgcagg tcggtgttac   3540

acacattcac acttgcaggc gtgcaggtcg gtggtgttac acacattcac actgttgcag   3600

gcgtgcaggt ccgtggtgtt acacacatgc tgttgcaggc gtgcaggtcg gtggtgttac   3660

attcacactg ttgcaggtgt gcaggttggt gttacacaca ttcacactgt tgcaggcttg   3720

cggtcggtgg tgttacacac attcacactt gcaggcgtgc aggtcagtgg tgttacacac   3780

attcatgctg ttgcaggcat gcaggtcggt agtgttacac attcatgctg ttgcaggcgt   3840

gcaggtcggt ggtgttgcac attcatgctg ttgcaggcat gcaggtcggt ggtgttacat   3900

tcacgctgtt gcaggagtac aggtcagtgg tgttacacac attcatgctg ttgtgcagct   3960

atcacttcca tctccagagc ccttttcatc ttaaaactga agctctccca tcacacagtg   4020

acccttcatg tccctcccca gtccctgaaa aacactgttc aggtttttct tcctggacct   4080

cattgtgtgg agttcctcgt gtgagtgcag tcacacacga tttgtccttt ttttgttttc   4140

gtttgttgag acagagtctc attctgtcac tcaggctgga gtgcagtggc gtgatctcag   4200

ctcactgcaa cctccactcc caggttcaag tgattctcct gcctcagcct cccaagtagc   4260

tgggattaca ggcgcctgcc accacgccca gctaattttt gtgtttttat tagagacagg   4320

gtttcaccaa gttggccaga ctggtctcaa actcctgacc tcgtgatcca cccgcctggg   4380

cctcccacag tgctgggatg acaggcgtga gctaccacac ccggctgatt tatcctttta   4440

tttgggctcc tttcactcag cgtctttaag cttcatacgc gaaagatgct tcagagattc   4500

ctttttcagg ctgaatatct gctgcgtggc taggccactt tttgtttaat cctctctcct   4560

ctggtggaca ccaggactgt gctgttttgg ttgctgtaag cgcgggtgca cacgcctgcc   4620

tgaggctgtg ttttggccgt tgtgagtgtg agtgcacaca cctgcctgag gctctgcttt   4680

gttgtgagtg cgggtgcaca cacctgcctg aggctgtgtt ttgggtgttg tgagtgtggg   4740

tgcacacacc tgcctgaggc tgtgttttgg gtgttgtgag tgtgggtgca cacacctgcc   4800

tgaggctgtg gcgcgatctc ggctcactgc aacctccacc tcccgggttc aagcgattct   4860

cctgcctcag cctcccgagt agctgggacc acacccacca ccacaccccg ttattttttt   4920

gtatttttag tagagatggg gttttgccat gttggccagg atggtctgga actgacctca   4980

ggtgatccac ccactggcct cccaaagtgc tgggattaca ggtgtgagcc actgtgcccg   5040

gcctcttttt actttgttaa tggtgtattt tgatagataa cagattgtca ttttcatgaa   5100

gcacagctgg ttagtttatt gttgctcatg tatttggcct catgttcgag tccctgtttt   5160

taatcatgag ctggacacag ccctctttag agcaactgtg accacttgtg gtgagaagtg   5220

cagcccacac catccacgtg aggctcccac acgccatcca cgtgaggctc ccatgcagac   5280

atttagaagg cgttttcact gcagctcaga aaatggcccc aggcccccat gggcaccccc   5340

atgtcaccag ggcctctggt tgctgccggt acacagggat aggcagccag gcctcgaagg   5400

tgctgggcat gggtttgggt gtctgcgttg ggtagagacc cggagcgccc ttgctgggcg   5460

tgccctaaca tcccggtacc ctgtgcccct ctgtgggcca ggacgcctgg tgctgccagc   5520

tgggcgtaag ccctgaggag ctgagggtgg ctgtgacttg gaggatgagt aggagctcac   5580

caggagggcg tggagccgag gcgtttaata tcatcaggag caacactggg ctcagaaggc   5640

aggcacactt gccgtccctc cagagccatg gctgacggcc aggcctggtg ggctctcgtg   5700

aggacagtgc ctgtggttgt cagatgctgt cccttcgagt aagggatgag agccatcctg   5760

aagatgggtc agctctgtgg tgaccacccg ttgggagcag tgacattcag gaggcagtgg   5820

agaaggtgac acagcacatc cacggcctgt ctgggaagaa ggatgggctg gtgcccatgt   5880

tcatcaatac ccacagtggc ctcttcaccc acctgggcgt attcacgctg ggcgccaggg   5940

ccgacagcta ctatgagtac ctgctgaagc agtggatcca gggcgggaag caggagacac   6000

agctgctgga agactacgtg gaagccatcg agggtgtcag aacgcacctg ctgcggcact   6060

ccgagcccag taagctcacc tttgtggggg agcttgccca cggccgcttc agtgccaaga   6120

tggaccacct ggtgtgcttc ctgccaggga cgctggctct gggcgtctac cacggcctgc   6180

ccgccagcca catggagctg gcccaggagc tcatggagac ttgttaccag atgaaccggc   6240

agatggagac ggggctgagt cccgagatcg tgcacttcaa cctttacccc cagccgggcc   6300

gtcgggacgt ggaggtcaag ccagcagaca ggcacaacct gctgcggcca gagaccgtgg   6360

agagcctgtt ctacctgtac cgcgtcacag gggaccgcaa ataccaggac tggggctggg   6420

agattctgca gagcttcagc cgattcacac gggtcccctc gggtggctat tcttccatca   6480

acaatgtcca ggatcctcag aagcccgagc ctagggacaa gatggagagc ttcttcctgg   6540

gggagacgct caagtatctg ttcttgctct tctccgatga cccaaacctg ctcagcctgg   6600

atgcctacgt gttcaacacc gaagcccacc ctctgcctat ctggacccct gcctagggtg   6660

gatggctgct ggtgtgggga cttcgggtgg gcagaggcac cttgctgggt ctgtggcatt   6720

ttccaagggc ccacgtagca ccggcaaccg ccaagtggcc caggctctga actggctctg   6780

ggctcctcct cgtctctgct ttaatcagga caccgtgagg acaagtgagg ccgtcagtct   6840

tggtgtgatg cggggtgggc tgggccgctg gagcctccgc ctgcttcctc cagaagacac   6900

gaatcatgac tcacgattgc tgaagcctga gcaggtctct gtgggccgac cagagggggg   6960

cttcgaggtg gtccctggta ctggggtgac cgagtggaca gcccagggtg cagctctgcc   7020

cgggctcgtg aagcctcaga tgtccccaat ccaagggtct ggaggggctg ccgtgactcc   7080

agaggcctga ggctccaggg ctggctctgg tgtttacaag ctggactcag ggatcctcct   7140

ggccgccccg cagggggctt ggagggctgg acggcaagtc cgtctagctc acgggcccct   7200

ccagtggaat gggtcttttc ggtggagata aaagttgatt tgctctaaaa aaaaaaaaaa   7260

aaaaa                                                               7265


<210>  569
<211>  3623
<212>  DNA
<213>  Human

<400>  569
ttttcctcac actaaatcga aaactctccc tgttggtcct gatctgtttc agtcaggcaa     60

attacatcct gggaaaacgt cagatgacag gggaggccac tcgcttcctg ctcatccagt    120

ttcgacactt tctgtgcttt cattagcttc cagacctcag ccctggccct cgctttactg    180

tacagtcaga actggtttct acgcctcgcg agggtgggag gtcgtgtatg ggaggaggac    240

cgcttcccac cagcctcgtt gggaagccag gagaaatctc ttcaaatcct gcgattcaga    300

gtcaagtccc agtcgtcctt tttctggtcg gcccagaact gtttgtgcct cctccctcat    360

gaggaatgat gtcagtgggg ccgcggtcgc cgcccacgaa gagtgtaagg ctgcgaagtc    420

ggggctttcc cgacgccccc tccgtccgcg tctgcgtagg ggaggtgacg agggcggggc    480

gcggcggcgg ggtgacgtca cggccgcgcg cggcgtgggc ggagcctcac tttgaaccca    540

gttggcggga gtggctgctc gcggaggggc agtgtctgcg gggccgctgt atgctgtcca    600

gcgatggatc ccaccgcggg aagcaagaag gagcctggag gaggcgcggc gactgaggag    660

ggcgtgaata ggatcgcagt gccaaaaccg ccctccattg aggaattcag catagtgaag    720

cccattagcc ggggcgcctt cgggaaagtg tatctggggc agaaaggcgg caaattgtat    780

gcagtaaagg ttgttaaaaa agcagacatg atcaacaaaa atatgactca tcaggtccaa    840

gctgagagag atgcactggc actaagcaaa agcccattca ttgtccattt gtattattca    900

ctgcagtctg caaacaatgt ctacttggta atggaatatc ttattggggg agatgtcaag    960

tctctcctac atatatatgg ttattttgat gaagagatgg ctgtgaaata tatttctgaa   1020

gtagcactgg ctctagacta ccttcacaga catggaatca tccacaggga cttgaaaccg   1080

gacaatatgc ttatttctaa tgagggtcat attaaactga cggattttgg cctttcaaaa   1140

gttactttga atagagatat taatatgatg gatatcctta caacaccatc aatggcaaaa   1200

cctagacaag attattcaag aaccccagga caagtgttat cgcttatcag ctcgttggga   1260

tttaacacac caattgcaga aaaaaatcaa gaccctgcaa acatcctttc agcctgtctg   1320

tctgaaacat cacagctttc tcaaggactc gtatgcccta tgtctgtaga tcaaaaggac   1380

actacgcctt attctagcaa attactaaaa tcatgtcttg aaacagttgc ctccaaccca   1440

ggaatgcctg tgaagtgtct aacttctaat ttactccagt ctaggaaaag gctggccaca   1500

tccagtgcca gtagtcaatc ccacaccttc atatccagtg tggaatcaga atgccacagc   1560

agtcccaaat gggaaaaaga ttgccaggaa agtgatgaag cattgggccc aacaatgatg   1620

agttggaatg cagttgaaaa gttatgcgca aaatctgcaa atgccattga gacgaaaggt   1680

ttcaataaaa aggatctgga gttagctctt tctcccattc ataacagcag tgcccttccc   1740

accactggac gctcttgtgt aaaccttgct aaaaaatgct tctctgggga agtttcttgg   1800

gaagcagtag aactggatgt aaataatata aatatggaca ctgacacaag tcagttaggt   1860

ttccatcagt caaatcagtg ggctgtggat tctggtggga tatctgaaga gcaccttggg   1920

aaaagaagtt taaaaagaaa ttttgagttg gttgactcca gtccttgtaa aaaaattata   1980

cagaataaaa aaacttgtgt agagtataag cataacgaaa tgacaaattg ttatacaaat   2040

caaaatacag gcttaacagt tgaagtgcag gaccttaagc tatcagtgca caaaagtcaa   2100

caaaatgact gtgctaataa ggagaacatt gtcaattctt ttactgataa acaacaaaca   2160

ccagaaaaat tacctatacc aatgatagca aaaaacctta tgtgtgaact cgatgaagac   2220

tgtgaaaaga atagtaagag ggactactta agttctagtt ttctatgttc tgatgatgat   2280

agagcttcta aaaatatttc tatgaactct gattcatctt ttcctggaat ttctataatg   2340

gaaagtccat tagaaagtca gcccttagat tcagatagaa gcatcaaaga atcctctttt   2400

gaagaatcaa atattgaaga tccacttatt gtaacaccag attgccaaga aaagacctca   2460

ccaaaaggtg tcgagaaccc tgctgtacaa gagagtaacc aaaaaatgtt aggtcctcct   2520

ttggaggtgc tgaaaacgtt agcctctaaa agaaatgctg ttgcttttcg aagttttaac   2580

agtcatatta atgcatccaa taactcagaa ccatccagaa tgaacatgac ttctttagat   2640

gcaatggata tttcgtgtgc ctacagtggt tcatatccca tggctataac ccctactcaa   2700

aaaagaagat cctgtatgcc acatcagacc ccaaatcaga tcaagtcggg aactccatac   2760

cgaactccga agagtgtgag aagaggggtg gcccccgttg atgatgggcg aattctagga   2820

accccagact accttgcacc tgagctgtta ctaggcaggg cccatggtcc tgcggtagac   2880

tggtgggcac ttggagtttg cttgtttgaa tttctaacag gaattccccc tttcaatgat   2940

gaaacaccac aacaagtatt ccagaatatt ctgaaaagag atatcccttg gccagaaggt   3000

gaagaaaagt tatctgataa tgctcaaagt gcagtagaaa tacttttaac cattgatgat   3060

acaaagagag ctggaatgaa agagctaaaa cgtcatcctc tcttcagtga tgtggactgg   3120

gaaaatctgc agcatcagac tatgcctttc atcccccagc cagatgatga aacagatacc   3180

tcctattttg aagccaggaa tactgctcag cacctgactg tatctggatt tagtctgtag   3240

cacaaaaatt ttccttttag tctagccttg tgttatagaa tgaacttgca taattatata   3300

ctccttaata ctagattgat ctaaggggga aagatcatta tttaacctag ttcaatgtgc   3360

ttttaatgta cgttacagct ttcacagagt taaaaggctg aaaggaatat agtcagtaat   3420

ttatcttaac ctcaaaactg tatataaatc ttcaaagctt ttttcattta tttattttgt   3480

ttattgcact ttatgaaaac tgaagcatca ataaaattag aggacactat tgagagtgag   3540

ccactagctt gattttcttt ctcctctgat ttcagttcac tgttcagttt agcattaaaa   3600

taataaaata atcatacagt tcc                                           3623


<210>  570
<211>  2825
<212>  DNA
<213>  Human

<400>  570
cacacggcca tggcggaggc ctcctcgctg gggaggcaga gtcctcgcgt ggtctcctgc     60

ctcgagcaca gcctgtgccc aggggagccg ggcttgcaga caacagcagt ggtgtccatg    120

ggctctggag accatcagtt caacctcgca gagatcctgt cacagaacta cagtgttagg    180

ggggagtgcg aggaggcctc gaggtgccca gacaagccca aggaggagct ggagaaggac    240

ttcatctccc agagcaacga catgcccttt gatgagctgc ttgcgctcta tggctacgag    300

gcgtcagacc ccatttcaga ccgggagagt gagggtggtg acgtggcccc gaacctccca    360

gacatgaccc tggacaaaga acaaatagcg aaggatttgc tttcagggga agaagaggaa    420

gagacgcaat catctgctga cgacctcacc ccgtccgtga cctcccacga ggcctccgac    480

ctcttcccta accggagtgg atctcgtttc ctggctgatg aagacagaga gcctggctct    540

tctgcctcct ccgacaccga ggaggactct cttcctgcca acaaatgtaa gaaggagatc    600

atggtgggac ctcagttcca agctgacctc agcaacctgc acttgaaccg gcactgtgag    660

aagatctacg agaacgaaga ccagctgctc tgggacccca gcgtcctccc tgagagggag    720

gtggaggagt tcctgtacag ggcggtgaag cggcgttggc acgagatggc cgggcctcag    780

ctcccagagg gagaagccgt gaaagacagt gagcaggcgc tgtacgagtt ggtgaaatgc    840

aacttcaatg tggaggaggc cctgcgaagg ctgcggttca acgtgaaggt gatccgagat    900

gggctctgtg cttggagtga agaggagtgc aggaactttg agcacggctt ccgtgtgcat    960

ggaaagaact ttcacctgat ccaggccaac aaggtgcgca cacggtcagt gggcgagtgt   1020

gtcgagtact actacctgtg gaagaagtcg gagcgctacg actacttcgc ccagcagacg   1080

cggctgggcc ggaggaagta cgtcccgtcc ggaaccacgg acgcagacca ggacctggat   1140

ggcagcgacc ccgatggccc cggccgtccg cgcccggagc aagacaccct gactgggatg   1200

cgcacagatc cactgagcgt ggatggcacg gccggtggtc tcgatgagcc cggagtggcc   1260

tctgatggac tcccgtcctc ggagccaggg ccgtgttcct tccagcagct ggatgagtcc   1320

cccgctgtac ccctgtccca tcggccccca gccctggccg acccagcctc ataccagcca   1380

gctgtcactg ctccggagcc agacgccagc ccaaggctgg ccgtggactt cgccctgccc   1440

aaggagctgc ccctcatctc cagccatgtg gacctcagcg gggatccgga ggagactgtg   1500

gccccagcac aggtggcttt gtcggtcacc gagtttggac tcatcggcat tggggacgtg   1560

aaccccttcc tggccgccca ccccacgtgc ccggcccccg ggctacactc ggagcccctg   1620

tcacactgta acgtgatgac ctgctgactc ctggccgcgg gcggcgtatg cggcccagac   1680

tggacttagc gctgccgctg ggcccgcctc tgtcagtctt cctgacccct tccccacccc   1740

ccgggccttg gggtagcacc tccttctgct tcagaacacg tcaggactgg ggtgaggtgg   1800

ctgggccgtg agcccttgcc cctgtccaca cagaatggac ccacggcccc acccagcgcc   1860

gtcagcgccc ggcactgcca cccgggtccg ggccgctgcc tgcacgtggg atccgtcggg   1920

cagccgggga cagaagagac cccgccgttg ggacgcaggg cagagccggc cacctagtcc   1980

cttccagcca gcagaggcga gggaaggcgt cactgccccg gcggggagac gggcaggacg   2040

ccctgccccg caccagcagc ctccgccggg gcgccctcag ctccctgctt ggctctgtct   2100

ctccacaccc ggcagggccg cgggctgccc cagccctggg ggtcgtgggc agctgctact   2160

cagtgccaac cccgtggggc acagagccat atacctcgct gtccggcccc caccccagcc   2220

tcgccttccc accccatcgt ctccacttca ggaaaagccg cactttacac ccccacctgc   2280

ctcttccccc tccatccctg ctccccgatc ctgagcggtt ggggtggggt ccctcagcaa   2340

ccccaggcgt gggtttgagg agacaggtga tttacatccc ctttgctgtc ctcccccggt   2400

accaaggcag ggagcctccg gaggagccgg ccctgctggc cacgcagggg ccagactcca   2460

gcctgtttcc ccagccctgc aggtcttcct tctgtgggaa gcttcctagc aagatggctt   2520

ggagtcctgg tccccctcct ccctggccct ctcgttcgtt tctgtttctg tttacacgtt   2580

ggagtggggt cctccgtggg cggcggcgcg ccctgccccg ggtgtcgtcc ggcctcttgt   2640

gctcgagccc ctttccgagt tggactcgac catccctcac cccaccaagg accacactgt   2700

gaagtgataa ctgccttgaa cccccctttg ctgttttatt tattaaactt gatttgaagc   2760

ccaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   2820

aaaaa                                                               2825


<210>  571
<211>  3886
<212>  DNA
<213>  Human

<400>  571
aaacgtcatc aggaatgcgc ccatgagagc gctattagat tggctggagg gagggcggtg     60

tcggcctacg cccccagagt cgtccggctg acgctggcgg tggcgcggtt tgtgtgggct    120

tggtgagggc ggggaggcct ggctgtgtgg atgtctgaca ggtgaggcgg gggacgcaga    180

agtgcagccg ccctctccca cagcggagtc caaaacaggc ctaccagtca gttcttattt    240

ctattgggtg tttccatgct ccaccatgtt aagagctaag aatcagcttt ttttactttc    300

acctcattac ctgaggcagg taaaagaatc atcaggctcc aggctcatac agcaacgact    360

tctacaccag caacagcccc ttcacccaga atgggctgcc ctggctaaaa agcagctgaa    420

aggcaaaaac ccagaagacc taatatggca caccccggaa gggatctcta taaaaccctt    480

gtattccaag agagatacta tggacttacc tgaagaactt ccaggagtga agccattcac    540

acgtggacca tatcctacca tgtatacctt taggccctgg accatccgcc agtatgctgg    600

ttttagtact gtggaagaaa gcaataagtt ctataaggac aacattaagg ctggtcagca    660

gggattatca gttgcctttg atctggcgac acatcgtggc tatgattcag acaaccctcg    720

agttcgtggt gatgttggaa tggctggagt tgctattgac actgtggaag ataccaaaat    780

tctttttgat ggaattcctt tagaaaaaat gtcagtttcc atgactatga atggagcagt    840

tattccagtt cttgcaaatt ttatagtaac tggagaagaa caaggtgtac ctaaagagaa    900

gcttactggt accatccaaa atgatatact aaaggaattt atggttcgaa atacatacat    960

ttttcctcca gaaccatcca tgaaaattat tgctgacata tttgaatata cagcaaagca   1020

catgccaaaa tttaattcaa tttcaattag tggataccat atgcaggaag caggggctga   1080

tgccattctg gagctggcct atactttagc agatggattg gagtactcta gaactggact   1140

ccaggctggc ctgacaattg atgaatttgc accaaggttg tctttcttct ggggaattgg   1200

aatgaatttc tatatggaaa tagcaaagat gagagctggt agaagactct gggctcactt   1260

aatagagaaa atgtttcagc ctaaaaactc aaaatctctt cttctaagag cacactgtca   1320

gacatctgga tggtcactta ctgagcagga tccctacaat aatattgtcc gtactgcaat   1380

agaagcaatg gcagcagtat ttggagggac tcagtctttg cacacaaatt cttttgatga   1440

agctttgggt ttgccaactg tgaaaagtgc tcgaattgcc aggaacacac aaatcatcat   1500

tcaagaagaa tctgggattc ccaaagtggc tgatccttgg ggaggttctt acatgatgga   1560

atgtctcaca aatgatgttt atgatgctgc tttaaagctc attaatgaaa ttgaagaaat   1620

gggtggaatg gccaaagctg tagctgaggg aatacctaaa cttcgaattg aagaatgtgc   1680

tgcccgaaga caagctagaa tagattctgg ttctgaagta attgttggag taaataagta   1740

ccagttggaa aaagaagacg ctgtagaagt tctggcaatt gataatactt cagtgcgaaa   1800

caggcagatt gaaaaactta agaagatcaa atccagcagg gatcaagctt tggctgaacg   1860

ttgtcttgct gcactaaccg aatgtgctgc tagcggagat ggaaatatcc tggctcttgc   1920

agtggatgca tctcgggcaa gatgtacagt gggagaaatc acagatgccc tgaaaaaggt   1980

atttggtgaa cataaagcga atgatcgaat ggtgagtgga gcatatcgcc aggaatttgg   2040

agaaagtaaa gagataacat ctgctatcaa gagggttcat aaattcatgg aacgtgaagg   2100

tcgcagacct cgtcttcttg tagcaaaaat gggacaagat ggccatgaca gaggagcaaa   2160

agttattgct acaggatttg ctgatcttgg ttttgatgtg gacataggcc ctcttttcca   2220

gactcctcgt gaagtggccc agcaggctgt ggatgcggat gtgcatgctg tgggcataag   2280

caccctcgct gctggtcata aaaccctagt tcctgaactc atcaaagaac ttaactccct   2340

tggacggcca gatattcttg tcatgtgtgg aggggtgata ccacctcagg attatgaatt   2400

tctgtttgaa gttggtgttt ccaatgtatt tggtcctggg actcgaattc caaaggctgc   2460

cgttcaggtg cttgatgata ttgagaagtg tttggaaaag aagcagcaat ctgtataata   2520

tcctcttttt gttttagctt ttgtctaaaa tattatttta gttatgatca aagaagagag   2580

taaagctatg tcttcaattt aatttcaata cctgatttgt actttccttg aaagctttac   2640

tttaaaatac cttacttata ggcctggtgt catgctataa gtatgtacat acagtttcac   2700

ttcaaaaata aaaaaaaaat ccctaaaaac tctctatact ctctataaca atactttatc   2760

aagaactctg gacaatggta ttatttttaa aaatcatggt gatgtattta ttagaatgtt   2820

tcttataaat ctgtttactt tttatattaa gaattaaact gtacctaaaa aaactctgac   2880

tattcccatt tgtcagttta gcattacatt gtcttgagca ccagaaaata aaatccatat   2940

attaataaaa acctatcttg aaaaactagt ggagtgtatt tacgtggcaa aagagatttt   3000

gggaggagtc ctcagccaaa ttctaccaga atcaccttaa taaaagaagt attaaaatca   3060

agcacagcag gttggaatat ggggaatttg acagtatatt tcttcaagtc tgagtttact   3120

ttcttcctga tcatgaccat ctgaccttgt tatttctggg cttggctcaa gaccaaggag   3180

agtggatgtt gatgaacatt cctttaaata aaagtgctta ggttgtagtt atggctttgt   3240

ctagaatggt gatgtcaact gtgagtgtag gtctgtgata tagaaagaat tcaactttcc   3300

agatctagaa agatgctacc ttgcatagat ttgctcctta aacataaatt gcaaaaataa   3360

aaatatcaca gagaacacct gtactttgct tactgaaaga tttgctcact aaagaaggaa   3420

agttgccatt tacctgttta acaaatctgc acatcctgca catgttcccc agaatgtaaa   3480

ataaaaaaag tttaaataaa aaaggaaagt tgtcctttat tgttaacatg atccattaca   3540

tgaatataac ataaataatt atctttttta ataaatttct attgtattag atcagagagc   3600

agtcttttgg aaagtattat agatacatta ctgtagaatt tacaaactca ttgtaataca   3660

atgtatttaa ttttcagaat atgattatct gaatggtatt gtcatgatta ttgttcccat   3720

tttcagatga acactgactt caagtccaat gatatattca ctatgccatt ttattgactt   3780

ttccttgtaa agcaatgcac actaatttag taagtatttg gtttctgtga tgtgttcagt   3840

tgcgtgctgg gtgacatgtg aaataaactc atccttgagg aattta                  3886


<210>  572
<211>  7546
<212>  DNA
<213>  Human

<400>  572
tccatccctg accgggccga ggctgctgga tgccgcgtct ccgcttctgc tgcctgccgg     60

gcgggctccg gtggccgcag caaagtgggg caccaaggcc ctgtgctaag cactcataat    120

cctctggggg tgctacccct acaaacagca cccccaccat gtttaaccta atgaagaaag    180

acaaggacaa agatggcggg cggaaggaga agaaggagaa aaaggagaaa aaggagcgga    240

tgtcagcggc agagcttcgg agcctggagg agatgagcct gcgacgtggc ttcttcaacc    300

tgaaccgctc ctccaagcgt gaatccaaga cgcgcctgga aatctccaac cccatcccca    360

tcaaggtggc cagcggctct gacctgcacc tgactgacat tgactccgat agtaaccggg    420

gcagcgtcat cctggactcg ggccacctaa gtacagccag ctccagcgat gacctcaagg    480

gtgaggaggg tagcttccgt ggctcggtgc tgcagcgggc agccaagttc ggctcactgg    540

ccaagcagaa ctcacagatg attgtcaagc gcttttcctt ctcccagcgt agccgggatg    600

agagcgcctc agaaacctcg acgccctcag agcactctgc cgccccctcg ccacaggtgg    660

aggtgaggac tctagaggga cagctggtgc agcatcctgg cccaggcatc cctcgaccag    720

ggcaccgatc ccgagcccct gagctagtga ctaaaaagtt cccagtcgac ctgcgcctgc    780

cccccgtggt gcccctgccc ccacctaccc tccgggagct ggagctgcaa cgacggccca    840

ctggagactt tggcttctcc ctgcggcgca caaccatgct ggatcggggc cccgagggcc    900

aggcctgtcg gcgtgtggtc cactttgctg agcctggtgc aggcaccaag gacctggccc    960

tggggctggt gccaggagat cgactggtgg agattaatgg gcacaatgtg gagagcaagt   1020

ccagggatga gattgtggag atgatccggc agtcagggga cagcgtgcgg ctcaaggtgc   1080

agcccattcc agagctcagc gagctcagca ggagctggct gcggagcggc gagggacctc   1140

gcagggagcc atccgatgcg aaaacagaag aacagattgc agcagaagag gcctggaatg   1200

agacggagaa ggtgtggctg gtccataggg acggcttctc actggccagt caactcaaat   1260

ctgaggagct caacttgcct gaggggaagg tgcgtgtgaa gctggaccac gatggggcca   1320

tcctggatgt ggatgaggat gacgttgaga aggctaatgc tccctcctgc gaccgtctgg   1380

aggatctggc ctcactggtg tacctcaatg agtccagcgt cctgcacacc ttgcgccagc   1440

gctatggcgc tagcctgctg cacacgtatg ctggccccag cctgctggtt cttggccccc   1500

gtggggcccc tgctgtgtac tctgagaagg tgatgcacat gttcaagggt tgtcggcggg   1560

aggacatggc accccacatc tatgcagtgg cccagaccgc atacagggcg atgctgatga   1620

gccgtcagga tcagtcaatc atcctcctgg gcagtagtgg cagtggcaag accaccagct   1680

gccagcatct ggtgcagtac ctggccacca tcgcgggcat cagcgggaac aaggtgtttt   1740

ctgtggagaa gtggcaggct ctgtacaccc tcctggaagc ctttgggaac agccccacca   1800

tcattaatgg caatgccacc cgcttctccc agatcctctc cctggacttt gaccaagctg   1860

gccaggtggc ctcagcctcc attcagacaa tgcttctgga gaagctgcgt gtggctcggc   1920

gcccagccag tgaagccaca ttcaacgtct tctactacct gctggcctgt ggggatggca   1980

ccctcaggac agagctccac ctcaaccact tggcagagaa caatgtgttt gggattgtgc   2040

cactggccaa gcctgaggaa aagcagaagg cagctcagca gtttagtaag ctgcaggcgg   2100

ccatgaaggt gctgggcatc tcccccgatg aacagaaggc ctgctggttc attctggctg   2160

ccatctacca cctgggggct gcgggagcca ccaaagaagc tgctgaagct gggcgcaagc   2220

agtttgcccg ccatgagtgg gcccagaagg ctgcgtacct actgggctgc agcctggagg   2280

agctgtcctc agccatcttc aagcaccagc acaagggtgg caccctgcag cgctccacct   2340

ccttccgcca gggccccgag gagagtggcc tgggagatgg gacaggcccg aaactgagtg   2400

cactggagtg ccttgagggc atggcggccg gcctctacag cgagctcttc acccttctcg   2460

tctccctggt gaatagggct ctcaagtcca gccagcactc actctgctcc atgatgattg   2520

tcgacacccc gggcttccag aaccctgagc agggtgggtc agcccgcgga gcctcctttg   2580

aggagctgtg ccacaactac acccaagacc ggctgcagag gctcttccac gagcgcacct   2640

tcgtgcagga gttggaaaga tacaaggagg agaacatcga gctggcgttt gacgacttgg   2700

aacccccgac ggatgactct gtggctgctg tggaccaggc ctcccatcag tccctggtcc   2760

gctcgctggc ccgcacagac gaggcgaggg gcctgctctg gctattggaa gaggaggctc   2820

tggtgccagg ggccagtgag gacaccctcc tggagcgcct tttctcctat tatggccccc   2880

aggaaggtga caaaaaaggc caaagccccc ttctgcacag cagcaaacca caccactttc   2940

tcctgggcca cagccatggc accaactggg tagagtacaa tgtgactggc tggctgaact   3000

acaccaagca gaacccagcc acccagaatg ccccccggct cctgcaggac tcccagaaaa   3060

aaatcatcag caacctgttt ctgggccgcg caggcagtgc cacggtgctc tctggctcca   3120

tcgcgggcct ggagggcggc tcgcagctgg cactgcgccg ggccaccagc atgcggaaaa   3180

cctttaccac aggcatggcg gctgtcaaaa agaagtcact gtgcatccag atgaagctac   3240

aggtggacgc cctcatcgac accatcaaga agtcaaagct gcattttgtg cactgcttcc   3300

tgcctgtagc tgagggctgg gctggggagc cccgttccgc ctcctcccgc cgagtcagca   3360

gcagcagtga gctggacctg ccctcgggag accactgcga ggctgggctc ctgcagctcg   3420

acgtgcccct gctccgcacc cagctccgcg gctcccgcct gctcgatgcc atgcgcatgt   3480

accgccaagg ttaccctgac cacatggtgt tttccgagtt ccgccgccgc tttgatgtcc   3540

tggccccgca cctgaccaag aaacacgggc gtaactacat cgtggtggat gaaaggcggg   3600

cagtggagga gctgctggag tgcttggatc tggagaagag cagctgctgc atgggcctga   3660

gccgggtgtt cttccgggcg ggcaccttgg cacggctgga ggagcagcgg gatgaacaaa   3720

ccagcaggaa cctaaccctg ttccaagcag cctgcagggg ctacctggcc cgccagcact   3780

tcaagaagag aaagatccag gacctggcca ttcgctgtgt acagaagaac atcaagaaga   3840

acaaaggggt gaaggactgg ccctggtgga agctttttac cacagtgagg cccctcatcg   3900

aagtacagct gtcagaggag cagatccgga acaaagacga ggagatccag cagctgcgga   3960

gcaagctcga gaaggcggag aaggagagga acgagctgcg gctcaacagt gaccggctgg   4020

agagccggat ctcagagctg acatcggagc tgacagatga gcgtaacaca ggagagtccg   4080

cctcccagct gctggacgcg gagacagcag agaggctccg ggctgagaag gagatgaagg   4140

aactgcagac ccagtacgat gcactgaaga agcagatgga ggttatggaa atggaggtga   4200

tggaggcccg tctcatccgg gcagcggaga tcaacgggga agtggatgat gatgatgcag   4260

gtggcgagtg gcggctgaag tatgagcggg ctgtgcggga ggtggacttc accaagaaac   4320

ggctccagca ggagtttgag gacaagctgg aggtggagca gcagaacaag aggcagctgg   4380

aacggcggct cggggacctg caggcagata gtgaggagag tcagcgggct ctgcagcagc   4440

tcaagaagaa gtgccagcga ctgacggctg agctgcaaga caccaagctg cacctggagg   4500

gccagcaggt ccgcaaccac gaactggaga agaagcagag gaggtttgac agtgagctct   4560

cgcaggcgca tgaggaggcc cagcgggaga agctgcagcg ggagaagctg cagcgggaga   4620

aggacatgct cctcgctgag gctttcagcc tgaagcagca actagaggaa aaagacatgg   4680

acattgcagg gttcacccag aaggttgtgt ctctagaggc agagctccag gacatttctt   4740

cccaagagtc caaggatgag gcttctctgg ccaaggtcaa gaaacagctc cgggacctgg   4800

aggccaaagt caaggatcag gaagaagagc tggatgagca ggcagggacc atccagatgc   4860

tggaacaggc caagctgcgt ctggagatgg agatggagcg gatgagacag acccattcta   4920

aggagatgga gagtcgggat gaggaggtgg aggaggcccg gcagtcgtgt cagaagaagt   4980

taaaacagat ggaggtgcag ctagaggaag agtatgagga caagcagaag gttctgcgag   5040

agaagcggga gctggagggc aagctcgcca ccctcagcga ccaggtgaac cggcgggact   5100

ttgagtcaga gaagcggctg cggaaggacc tgaagcgcac caaggccctg ctggcagatg   5160

cccagctcat gctggaccac ctgaagaaca gtgctcccag caagcgagag attgcccagc   5220

tcaagaacca gctggaggag tcagagttca cctgtgcggc agccgtgaaa gcacggaaag   5280

caatggaggt ggagatcgaa gacctgcacc tgcagattga tgacatcgcc aaagccaaga   5340

cagcgctgga ggagcagctg agccgccttc agcgtgagaa gaatgagatc cagaaccggc   5400

tggaggaaga tcaggaagac atgaacgaat tgatgaagaa gcacaaggct gccgtggctc   5460

aggcttcccg ggacctggct cagataaatg atctccaagc tcagctagaa gaagccaaca   5520

aagagaagca ggagctgcag gagaagctac aagccctcca gagccaggtg gagttcctgg   5580

agcagtccat ggtggacaag tccctggtga gcaggcagga agctaagata cgggagctgg   5640

agacacgcct ggagtttgaa aggacgcaag tgaaacggct ggagagcctg gctagccgtc   5700

tcaaggaaaa catggagaag ctgactgagg agcgggatca gcgcattgca gccgagaacc   5760

gggagaagga acagaacaag cggctacaga ggcagctccg ggacaccaag gaggagatgg   5820

gcgagcttgc caggaaggag gccgaggcga gccgcaagaa gcacgaactg gagatggatc   5880

tagaaagcct ggaggctgct aaccagagcc tgcaggctga cctaaagttg gcattcaagc   5940

gcatcgggga cctgcaggct gccattgagg atgagatgga gagtgatgag aatgaggacc   6000

tcatcaacag tgagggagac tctgatgtgg actcggagct ggaggaccgt gttgacgggg   6060

tcaagtcctg gttgtcaaaa aacaagggac cttccaaggc agcttctgat gatggcagct   6120

taaagagttc cagccccacc agctactgga agtcccttgc ccctgatcgg tcagatgatg   6180

agcacgaccc tctcgacaac acctccagac cgcgatactc ccacagttat ctgagtgaca   6240

gcgacacaga ggccaagctg acggagacta acgcatagcc caggggagtg gttggcagcc   6300

ctctcacccc agggcctgtg gctgcctggg cacctctccc aggaagtggt ggggcaccgg   6360

tctcccccac ccgactgctg atctgcatgg gaaacaccct gaccttcttc tgtcaggggc   6420

actttccagg ctatgggtgt ctgatgtctc cacgtggaag aggtggggga aagaggagtt   6480

tctgaagaga actttttgct cctctgtctc aaaatgccag actcttggct tctaccctgt   6540

gtcaccgtgg gcagtggcag gtggcctggc actgcatgga gccagcacgt tgacctccct   6600

ctcagctccc tgctcaggga cggtggacag gttgcctact gggacactct aggttgctgg   6660

gtccatgggg aggattgggg gaggagaagc agtgccttcc ctctcgtgtg gggtgggggc   6720

tctctcttct tggtgcctgc tgtctttcta ctttttaatt taaataccca acctctccat   6780

cacagctgca tccctgagag tgggaggggg ctgtagtggt agctggggct cccaagaacg   6840

actcgggaat gtcatctcca tcttcaccct tcagagagca gtcctttctc tgtgcagctg   6900

gagacgctgg tgaggagagc cgggtccagg ttcttaagaa tgaggtgcgg aggggctctc   6960

cggtgctgct gggctgggtt gagcaagcct acgcagacaa gtgtgtgtgt ggaccatccg   7020

cacctccagc ccccacccca ccctctttgt ctcagcgtgt tatgtgcaat gacctattta   7080

aggtaaaccc attccaacta cagcagttca gggctgatcc aagcactgcc tccctcctgc   7140

tctgtccagg tggtctggac cataaactca acttgagagg gaaggcttgg ggttgaggac   7200

ttgtgatcag aaaaactgaa gatggaagtt ttggccggtg ctcattagac atgagtcctc   7260

actctgtgtc ctgagcccgt gtcattcttc caacctccct gcccccacac acttatccca   7320

gacacaacac catgtggtct ggaggtccca gcccccaccc taaaaaggtt atccctgaga   7380

actccaccag acttgggagc ccaagtgcag tgcctggtgc tgctcccatc tgccgccccc   7440

cttctctcct gcaattggtt tgtactcact gggctgtgct ctcccctgtt tacccgatgt   7500

atggaaataa aggccctttt cctcctggct gcgccagtaa aaaaaa                  7546


<210>  573
<211>  1716
<212>  DNA
<213>  Human

<400>  573
agtgcgcctg cgcgcttgtg gagctggtgg cggcgctccg caggggctcg gctgttttcc     60

gcgcggcagg cgcggccatg gcgcagctgg gaaagctgct caaggagcag aagtacgacc    120

ggcagctgag gtattggttc gtttacaatt attgatggaa atcaggtcag cggagaagat    180

gctggaaaca atttcttcct tcaaagaagc agtatcggca agaaccgagc tgaagctgcc    240

atggaattct tacaagaatt aaatagcgat gtctctggaa gttttgtgga agagagtcca    300

gaaaaccttc tagacaatga tccctcattt ttctgtaggt ttactgttgt agttgcaact    360

cagcttcctg aaagcacttc actacgctta gcagatgtcc tctggaattc ccagattcct    420

cttttgatct gtaggacata tggactagtt ggttatatga ggatcattat aaaagaacat    480

ccagtaatag aatctcatcc agataatgca ttagaggatc tacgactaga taagccattt    540

cctgaactga gagaacattt tcagtcctat gatttggatc atatggaaaa aaaggaccac    600

agtcatactc catggattgt gatcatagct aaatatttag cacagtggta tagtgaaaca    660

aatggacgaa tacctaaaac gtataaagaa aaagaggact tcagagattt gattagacaa    720

ggaattctaa aaaatgaaaa tggggctcca gaagatgaag agaattttga agaagctatt    780

aaaaatgtga acacagcact aaatacaact cagatcccaa gcagtattga agatatattt    840

aatgatgatc gctgcataaa tatcaccaaa cagactccat cattttggat tttagctcgt    900

gccttaaagg aatttgtggc caaagagggt caaggaaatt tacctgttcg aggcacaatt    960

cctgatatga ttgcagattc aggcaaatat ataaaactgc aaaacgttta ccgtgaaaaa   1020

gcaaagaaag atgctgccgc tgtgggtaat catgttgcca aattgctgca gtccattggc   1080

caggcaccag agtccatttc agagaaagaa ttaaaattac tctgcagcaa ttctgcattt   1140

cttcgagtgg taagatgtcg atccttagct gaagaatatg gtttggatac aattaacaag   1200

gatgaaatta tttctagcat ggacaatcca gataatgaaa tagtgttgta cttaatgtta   1260

cgggctgttg atagatttca taaacaacag ggtagatatc caggagtatc taactatcaa   1320

gttgaagaag atataggaaa gttgaagtct tgtctcactg gcttccttca ggaatatggt   1380

ttatctgtaa tggtgaaaga tgattatgtc cacgaatttt gccgatatgg agctgctgag   1440

ccacatacca ttgctgcatt cttgggggga gctgctgctc aagaggtcat caaaataatc   1500

accaaacaat ttgtaatttt taataatact tacatttaca gtggcatgtc acaaacttca   1560

gcaactttcc agttgtagag taagcaagca ccttaagtag tgtgttaatg attgaaactg   1620

taattgcctt cgggttgtgc tttagtctgt aaaattctaa aggagagctg ctaaattgtt   1680

ttcttaataa acatttttct catttgtaaa aaaaaa                             1716


<210>  574
<211>  3188
<212>  DNA
<213>  Human

<400>  574
ctctgtggtt cgggtccgct ttcgtctccg tcctgctgcc gttaccgccg ctgctgccgc     60

cgcttgcgtc ccccgctccg gtctgtggtg cagccgggac ccaggaccat gtctctgtct    120

cgctcagagg agatgcaccg gctcacggaa aatgtctata agaccatcat ggagcagttc    180

aaccctagcc tccggaactt catcgccatg gggaagaatt acgagaaggc actggcaggt    240

gtgacgtatg cagccaaagg ctactttgac gccctggtga agatggggga gctggccagc    300

gagagccagg gctccaaaga actcggagac gttctcttcc agatggctga agtccacagg    360

cagatccaga atcagctgga agaaatgctg aagtcttttc acaacgagct gcttacgcag    420

ctggagcaga aggtggagct ggactccagg tatctgagtg ctgcgctgaa gaaataccag    480

actgagcaaa ggagcaaagg cgacgccctg gacaagtgtc aggctgagct gaagaagctt    540

cggaagaaga gccagggcag caagaatcct cagaagtact cggacaagga gctgcagtac    600

atcgacgcca tcagcaacaa gcagggcgag ctggagaatt acgtgtccga cggctacaag    660

accgcactga cagaggagcg caggcgcttc tgcttcctgg tggagaagca gtgcgccgtg    720

gccaagaact ccgcggccta ccactccaag ggcaaggagc tgctggcgca gaagctgccg    780

ctgtggcaac aggcctgtgc cgaccccagc aagatcccgg agcgcgcggt gcagctcatg    840

cagcaggtgg ccagcaacgg cgccaccctc cccagcgccc tgtcggcctc caagtccaac    900

ctggtcattt ccgaccccat tccgggggcc aagcccctgc cggtgccccc cgagctggca    960

ccgttcgtgg ggcggatgtc tgcccaggag agcacaccca tcatgaacgg cgtcacaggc   1020

ccggatggcg aggactacag cccgtgggct gaccgcaagg ctgcccagcc caaatccctg   1080

tctcctccgc agtctcagag caagctcagc gactcctact ccaacacact ccccgtgcgc   1140

aagagcgtga ccccaaaaaa cagctatgcc accaccgaga acaagactct gcctcgctcg   1200

agctccatgg cagccggcct ggagcgcaat ggccgtatgc gggtgaaggc catcttctcc   1260

cacgctgctg gggacaacag caccctcctg agcttcaagg agggtgacct cattaccctg   1320

ctggtgcctg aggcccgcga tggctggcac tacggagaga gtgagaagac caagatgcgg   1380

ggctggtttc ccttctccta cacccgggtc ttggacagcg atggcagtga caggctgcac   1440

atgagcctgc agcaagggaa gagcagcagc acgggcaacc tcctggacaa ggacgacctg   1500

gccatcccac cccccgatta cggcgccgcc tcccgggcct tccccgccca gacggccagc   1560

ggcttcaagc agaggcccta cagtgtggcc gtgcccgcct tctcccaggg cctggatgac   1620

tatggagcgc ggtccatgag cagtggcagc ggcacgctgg tgtccacagt gtgaggacgc   1680

tgaccccggg cagccgctgc tctgaagagc ttccgcgcct tccccctggt ctcgtccgtt   1740

ttcctcctca gctctcgctg gtttgttctt gggttgtttt tcttttccac ctgccccatg   1800

ccttttggtt ggtgacccca gactctgtga tcccccaggg tccatggtgc tgctccatcc   1860

gccccccctc ccctgtgttt acgcgcccca tcctgtgtgt cccagccttt tgagcagaaa   1920

ctgccaggca ggacctgctg ggccgtgcgg ggcaccctcg gcctcaccct gcagtgtctg   1980

tggcactcac tgcttttcta aggctcgccg tgagccaggt ctaaagtttg aagaaaaaga   2040

aaaatcttaa aaaaaaaaaa aaaaaaaaaa agaaaaaaag aaaaacagga aaaaggactt   2100

tttttttcct gaaaaacaaa aaccgatctg catggactcc ggtgtgcgct gttatctcgc   2160

atccgacttc cccggtgcga tggcctctgt ccggacaggg aaggtgctgg ggtccctggc   2220

cgccccggcc cctgtggagg ggtgcacaga gaaagggggc tcgtgccaag ctcgaggggc   2280

ctcctgagga agccggccgc tcctgtgagg gaggccgggc ccgggcacct gagggcttct   2340

ccctctggac actgcgggcc aggtgtacat agagcagcgc ggcacagtgg cctcacctcc   2400

cgtcgggcac tggcgggagc aaggtcgggg gcaggcgctg cccagctggc cgcacacgga   2460

cattccaaag acctccagag accaccccac ccccacattc ctttgaccag ccttgtgagg   2520

gcatcgatgc tgccccgggc tacctggctg ctctgggcag ggtgtgcggg ccgggcccgg   2580

ctgggggagg gcagctctgg gcacgccgca cccacgcccc ccacctgggg gaaacaggcg   2640

gttcctgccc ggttcttcct aaacgctctc gtctttttgt gtgtcttggt gactttagaa   2700

acaaacacag tggactcagt ggctactggt attgtctctt cccacactga actctgggga   2760

attgagtgca gggcacagcc cggctcagcc tgcccgctgg tgggagcccc tgggaagctg   2820

cggcgctcct ttatctgatg tggtttagta aaagcctccc acacacctcc ccgtggcctg   2880

ggacgtggct ggtagtgttt gtgtgggaag cagctcaaga cgcggaccgc gtgacattaa   2940

ggagagctca agggcggacc gggccctgtg tagagaccct tccgcgccgg cgttcccgct   3000

ccgctaaaga tttcaaatcc aggggattcc atgctcaatg gatgaatgta gacacaaaac   3060

agcaacactt gtatgaagat gtaaagtgct gaacatattt ttttcctgtt tcctttcctt   3120

ttttttaaaa aatctgaatt gtgccctgta ctgcagttac ttgtttgaat aaaagtttta   3180

tttattgc                                                            3188


<210>  575
<211>  1449
<212>  DNA
<213>  Human

<400>  575
agaaaggagt ggggttgaaa agcgcttgcg caggacggct acggtacggg ggtgggaggg     60

cttcggagca cgcgcgcgga ggcgggactt gggaagcgct cgcgagatct tcagggtcta    120

tatataagcg cggggagcct gcgtcctttc cctggtgtga ttccgtcctg cgcggttgtt    180

ctctggagca gcgttctttt atctccgtcc gccttctctc ctacctaagt gcgtgccgcc    240

acccgatgga agattcgatg gacatggaca tgagccccct gaggccccag aactatcttt    300

tcggttgtga actaaaggcc gacaaagatt atcactttaa ggtggataat gatgaaaatg    360

agcaccagtt atctttaaga acggtcagtt taggggctgg tgcaaaggat gagttgcaca    420

ttgttgaagc agaggcaatg aattacgaag gcagtccaat taaagtaaca ctggcaactt    480

tgaaaatgtc tgtacagcca acggtttccc ttgggggctt tgaaataaca ccaccagtgg    540

tcttaaggtt gaagtgtggt tcagggccag tgcatattag tggacagcac ttagtagctg    600

tggaggaaga tgcagagtca gaagatgaag aggaggagga tgtgaaactc ttaagtatat    660

ctggaaagcg gtctgcccct ggaggtggta gcaaggttcc acagaaaaaa gtaaaacttg    720

ctgctgatga agatgatgac gatgatgatg aagaggatga tgatgaagat gatgatgatg    780

atgattttga tgatgaggaa gctgaagaaa aagcgccagt gaagaaatct atacgagata    840

ctccagccaa aaatgcacaa aagtcaaatc agaatggaaa agactcaaaa ccatcatcaa    900

caccaagatc aaaaggacaa gaatccttca agaaacagga aaaaactcct aaaacaccaa    960

aaggacctag ttctgtagaa gacattaaag caaaaatgca agcaagtata gaaaaaggtg   1020

gttctcttcc caaagtggaa gccaaattca tcaattatgt gaagaattgc ttccggatga   1080

ctgaccaaga ggctattcaa gatctctggc agtggaggaa gtctctttaa gaaaatagtt   1140

taaacaattt gttaaaaaat tttccgtctt atttcatttc tgtaacagtt gatatctggc   1200

tgtccttttt ataatgcaga gtgagaactt tccctaccgt gtttgataaa tgttgtccag   1260

gttctattgc caagaatgtg ttgtccaaaa tgcctgttta gtttttaaag atggaactcc   1320

accctttgct tggttttaag tatgtatgga atgttatgat aggacatagt agtagcggtg   1380

gtcagacatg gaaatggtgg ggagacaaaa atatacatgt gaaataaaac tcagtatttt   1440

aataaagta                                                           1449


<210>  576
<211>  1762
<212>  DNA
<213>  Human

<400>  576
gctaatccca gtcggtgccg catccccagc ccgccgccat ggccgcctac aaactggtgc     60

tgatccggca cggcgagagc gcatggaacc tggagaaccg cttcagcggc tggtacgacg    120

ccgacctgag cccggcgggc cacgaggagg cgaagcgcgg cgggcaggcg ctacgagatg    180

ctggctatga gtttgacatc tgcttcacct cagtgcagaa gagagcgatc cggaccctct    240

ggacagtgct agatgccatt gatcagatgt ggctgccagt ggtgaggact tggcgcctca    300

atgagcggca ctatgggggt ctaaccggtc tcaataaagc agaaactgct gcaaagcatg    360

gtgaggccca ggtgaagatc tggaggcgct cctatgatgt cccaccacct ccgatggagc    420

ccgaccatcc tttctacagc aacatcagta aggatcgcag gtatgcagac ctcacagaag    480

atcagctacc ctcctgtgag agtctgaagg atactattgc cagagctctg cccttctgga    540

atgaagaaat agttccccag atcaaggagg ggaaacgtgt actgattgca gcccatggca    600

acagcctccg gggcattgtc aagcatctgg agggtctctc tgaagaggct atcatggagc    660

tgaacctgcc gactggtatt cccattgtct atgaattgga caagaacttg aagcctatca    720

agcccatgca gtttctgggg gatgaagaga cggtgcgcaa agccatggaa gctgtggctg    780

cccagggcaa ggccaagaag tgaaggccgg cggggaggat actgtcccca ggagcaccct    840

ccctgcccgt cttgtccctc tgcccctccc acctgcacat gtcacactga ccacatctgt    900

agacatcttg agttgtagct gcagacgggg accagtggct cccattttca ttttagccat    960

tttgtcgcct gcacccactc ccttcataca atctagtcag aatagcagtt ctagagcaca   1020

ggttctcagt ctaagctatg gaaaagctcc ccttatccaa cagagtttaa aagtagtgac   1080

ttgggttttt gcgagtgctt tgtttactaa ggactttggg gaggaaccat gctaagccat   1140

gaccagtgag gagaagcaac agagcctgtc tgtccccatg agcggagtct gtcctctgct   1200

cttctgcagt caggtcactg cctactgcct gggggctcta gtcattccag tggaagacga   1260

atgtaacctg cgtggtgatg tgacaactgt ttcctccctg accccagagg atctggctct   1320

aggttgggat caatcctgaa tttcgttatg tgttaattta cttttattaa aaaagtatag   1380

tatatataat acaaaacaat aacccttctg gggtttcttg tggcggttga aatagtccca   1440

catgtggtca tcagaaaata agccattcct cataccaata taggatcagc tccttgacct   1500

ctgaggggca ggagtgcttc ctggtgtgtg tattagaatc ccttcctgcc ttgtttcatg   1560

gcagtgaaat gcctcttggt cctgtccaag tgtatctttc actgatttct gaatcatgtt   1620

ctagttgctt gaccctgcca catgggtcca gtgttcatct gagcataact gtactaaatc   1680

ctttttccat atcagtataa taaaggagtg atgtgcaata aaaaaaaaaa aaaaaaaaaa   1740

aaaaaaaaaa aaaaaaaaaa aa                                            1762


<210>  577
<211>  2234
<212>  DNA
<213>  Human

<400>  577
aactggctcc gattggctgt ggtacagcag gtgccgcgtc cggattgatc aaagccaggt     60

gggcggggct gtcgcccagg gtgactctcc cgggaggcgc gtgcccaggc tcagtagcat    120

tggggctggc gcgcgcggcg aatctcaacg ctgcgccgtc tgcgggcgct tccgggccac    180

cagtttctct gctttccacc ctggcgcccc ccagccctgg ctccccagct gcgctgcccc    240

gggcgtccac gccctgcggg cttagcgggt tcagtgggct caatctgcgc agcgccacct    300

ccatgttgac caagcctcta caggggcctc ccgcgccccc cgggaccccc acgccgccgc    360

caggaggcaa ggatcgggaa gcgttcgagg ccgagtatcg actcggcccc ctcctgggta    420

aggggggctt tggcaccgtc ttcgcaggac accgcctcac agatcgactc caggtggcca    480

tcaaagtgat tccccggaat cgtgtgctgg gctggtcccc cttgtcagac tcagtcacat    540

gcccactcga agtcgcactg ctatggaaag tgggtgcagg tggtgggcac cctggcgtga    600

tccgcctgct tgactggttt gagacacagg agggcttcat gctggtcctc gagcggcctt    660

tgcccgccca ggatctcttt gactatatca cagagaaggg cccactgggt gaaggcccaa    720

gccgctgctt ctttggccaa gtagtggcag ccatccagca ctgccattcc cgtggagttg    780

tccatcgtga catcaaggat gagaacatcc tgatagacct acgccgtggc tgtgccaaac    840

tcattgattt tggttctggt gccctgcttc atgatgaacc ctacactgac tttgatggga    900

caagggtgta cagcccccca gagtggatct ctcgacacca gtaccatgca ctcccggcca    960

ctgtctggtc actgggcatc ctcctctatg acatggtgtg tggggacatt ccctttgaga   1020

gggaccagga gattctggaa gctgagctcc acttcccagc ccatgtctcc ccagactgct   1080

gtgccctaat ccgccggtgc ctggccccca aaccttcttc ccgaccctca ctggaagaga   1140

tcctgctgga cccctggatg caaacaccag ccgaggatgt acccctcaac ccctccaaag   1200

gaggccctgc ccctttggcc tggtccttgc taccctaagc ctggcctggc ctggcctggc   1260

ccccaatggt cagaagagcc atcccatggc catgtcacag ggatagatgg acatttgttg   1320

acttggtttt acaggtcatt accagtcatt aaagtccagt attactaagg taagggattg   1380

aggatcaggg gttagaagac ataaaccaag tctgcccagt tcccttccca atcctacaaa   1440

ggagccttcc tcccagaacc tgtggtccct gattctggag ggggaacttc ttgcttctca   1500

ttttgctaag gaagtttatt ttggtgaagt tgttcccatt ctgagccccg ggactcttat   1560

tctgatgatg tgtcacccca cattggcacc tcctactacc accacacaaa cttagttcat   1620

atgctcttac ttgggcaagg gtgctttcct tccaataccc cagtagcttt tattttagta   1680

aagggaccct ttcccctagc ctagggtccc atattgggtc aagctgctta cctgcctcag   1740

cccaggattc tttattctgg gggaggtaat gccctgttgt taccccaagg cttctttttt   1800

tttttttttt ttttgggtga ggggacccta ctctgttatc ccaagtgctc ttattctggt   1860

gagaagaacc ttacttccat aatttgggaa ggaatggaag atggacacca ccggacacca   1920

ccagacacta ggatgggatg gatggttttt tgggggatgg gctaggggaa ataaggcttg   1980

ctgtttgttc tcctggggcg ctccctccaa cttttgcaga ttcttgcaac ctcctcctga   2040

gccgggattg tccaattact aaaatgtaaa taatcacgta ttgtggggag gggagttcca   2100

agtgtgccct cctctcttct cctgcctgga ttatttaaaa agccatgtgt ggaaacccac   2160

tatttaataa aagtaataga atcagaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   2220

aaaaaaaaaa aaaa                                                     2234


<210>  578
<211>  3484
<212>  DNA
<213>  Human

<400>  578
gtgcgagccc ggccgccggt gagtcggctg gagcgcatct ggtcctccgc gcggaaagcg     60

ctgcttttgc ctggccgccc tagccgctgg ctcatccaag tggccttcgc cgctctcttg    120

cgtcccaacc agagcgctgg ccacctcgcc gcccagctca cgccgcgccc gcgctcccag    180

gctccgggtt ttcttaaatg ttttcttgga gccttaaaga tggagatgac agaaatgact    240

ggtgtgtcgc tgaaacgtgg ggcactggtt gtcgaagata atgacagtgg agtcccagtt    300

gaagagacaa aaaaacagaa gctgtcggaa tgcagtctaa ccaaaggtca agatgggcta    360

cagaatgact ttctgtccat cagtgaagac gtgcctcggc ctcctgacac tgtcagtact    420

gggaaaggtg gaaagaattc tgaggctcag ttggaagatg aggaagaaga ggaggaagat    480

ggactttcag aggagtgcga ggaggaggaa tcagagagtt ttgcagacat gatgaagcat    540

ggactcactg aggctgacgt aggcatcacc aagtttgtga gttctcatca agggttctcg    600

ggaatcttaa aagaaagata ctccgacttc gttgttcatg aaataggaaa agatggacgg    660

atcagccatt tgaatgactt gtccattcca gtggatgagg aggacccttc agaagacata    720

tttacagttt tgacagctga agaaaagcag cgattggaag agctccagct gttcaaaaat    780

aaggaaacca gtgttgccat tgaggttatc gaggacacca aagagaaaag aaccatcatc    840

catcaggcta tcaaatctct gtttccagga ttagagacaa aaacagagga tagggagggg    900

aagaaataca ttgtagccta ccacgcagct gggaaaaagg ctttggcaaa tccaagaaaa    960

cattcttggc caaaatctag gggaagttac tgccacttcg tactatataa ggaaaacaaa   1020

gacaccatgg atgctattaa tgtactctcc aaatacttaa gagtcaagcc aaatatattc   1080

tcctacatgg gaaccaaaga taaaagggct ataacagttc aagaaattgc tgttctcaaa   1140

ataactgcac aaagacttgc ccacctgaat aagtgcttga tgaactttaa gctagggaat   1200

ttcagctatc aaaaaaaccc actgaaattg ggagagcttc aaggaaacca cttcactgtt   1260

gttctcagaa atataacagg aactgatgac caagtacagc aagctatgaa ctctctcaag   1320

gagattggat ttattaacta ctatggaatg caaagatttg gaaccacagc tgtccctacg   1380

tatcaggttg gaagagctat actacaaaat tcctggacag aagtcatgga tttaatattg   1440

aaaccccgct ctggagctga aaagggctac ttggttaaat gcagagaaga atgggcaaag   1500

accaaagacc caactgctgc cctcagaaaa ctacctgtca aaaggtgtgt ggaagggcag   1560

ctgcttcgag gactttcaaa atatggaatg aagaatatag tctctgcatt tggcataata   1620

cccagaaata atcgcttaat gtatattcat agctaccaaa gctatgtgtg gaataacatg   1680

gtaagcaaga ggatagaaga ctatggacta aaacctgttc caggggacct cgttctcaaa   1740

ggagccacag ccacctatat tgaggaagat gatgttaata attactctat ccatgatgtg   1800

gtaatgccct tgcctggttt cgatgttatc tacccaaagc ataaaattca agaagcctac   1860

agggaaatgc tcacagctga caatcttgat attgacaaca tgagacacaa aattcgagat   1920

tattccttgt caggggccta ccgaaagatc attattcgtc ctcagaatgt tagctgggaa   1980

gtcgttgcat atgatgatcc caaaattcca cttttcaaca cagatgtgga caacctagaa   2040

gggaagacac caccagtttt tgcttctgaa ggcaaataca gggctctgaa aatggatttt   2100

tctctacccc cttctactta cgccaccatg gccattcgag aagtgctaaa aatggatacc   2160

agtatcaaga accagacgca gctgaataca acctggcttc gctgagcagt accttgtcca   2220

cagattagaa aacgtacaca agtgtttgct tcctggctcc ctgtgcattt ttgtcttagt   2280

tcagactcat atatggattt caaatctttg taataaaaat tatttgtatt tttaagtttt   2340

tattagctta aagaaataat ttgcaatatt tgtacatgta cacaaatcct gaggttctta   2400

attttagctc agaatataaa ttagtcaaaa tacacttcag gtgcttaaat cagagtaaaa   2460

tgtcagcttt acaataataa aaaaaggact ttggtttaaa gtagcaggtt taggttttgc   2520

tacattctca aaagacagca ggagtatttg acacatctgt gatggagtat acaacaatgc   2580

attttaagag caaatgcaac aaaacaaatc tggactatgg ataaataatt tgagagctgc   2640

cacccacaaa tataaataca gtactcatgc tgactgaaat aataagacat ctacaaattt   2700

ataaacaaaa agtgattgtc attatcctgc ttatgtacta gattcaggca agcattatag   2760

actttttggt tgcggtggct tttgcattta tattatcaat gccttgcagg aacgttgcat   2820

tgataggccc attttatttt tttatttttt ttttcgagac aggatctcac tctgtagcac   2880

aggctggatt gcagtgcaat cctgcaattc tcaatcttgc actgcagcct cgacctccca   2940

ggctccagtg actctcccac ctcagcctcc taagtagctg ggagtacagg cgcgcaccac   3000

cacgcctagc tgatttttgt atttttttgt agagacgggg gtttggccat gttgccgagg   3060

ctaactcctg ggattacagg catgagctgt gctggccggg tttttttttc ttgatgtaaa   3120

cgtgtacagc tgttttatta gttaaggtct aatttttact ctaggtgcct tttatgttca   3180

gaactctttc cactggactg gtatttgctc aaaaataaat aatggtagag aagaaaacta   3240

taaaaatgga caaggctttc ttctatcagt agcgtttacc ctttgtcacc agtggctttg   3300

gtatttccat gtctggcatt gcataaactt ctctggtgtg aaaggataaa tatgcctttc   3360

taaagttgta tatcaaaatt gtatcaattt ttattttcta tgatttctag aaacaaatgt   3420

aataaatatt tttaaaatct cctttctact ggttatgtaa ataaatcaaa taaatatatc   3480

aaaa                                                                3484


<210>  579
<211>  2425
<212>  DNA
<213>  Human

<400>  579
gctccggacg cgaggggcgg ggcgagcgcg ggacaaaggg aagcgaagcc ggagctgcgg     60

gcgctttttc tgcccgcggt gtctcagatt cattcttaag gaactgagaa cttaatcttc    120

caaaatgtca aaaagaccat cttatgcccc acctcccacc ccagctcctg caacacaaat    180

gcccagcaca ccagggtttg tgggatacaa tccatacagt catctcgcct acaacaacta    240

caggctggga gggaacccgg gcaccaacag ccgggtcacg gcatcctctg gtatcacgat    300

tccaaaaccc ccaaagccac cagataagcc gctgatgccc tacatgaggt acagcagaaa    360

ggtctgggac caagtaaagg cttccaaccc tgacctaaag ttgtgggaga ttggcaagat    420

tattggtggc atgtggcgag atctcactga tgaagaaaaa caagaatatt taaacgaata    480

cgaagcagaa aagatagagt acaatgaatc tatgaaggcc tatcataatt cccccgcgta    540

ccttgcttac ataaatgcaa aaagtcgtgc agaagctgct ttagaggaag aaagtcgaca    600

gagacaatct cgcatggaga aaggagaacc gtacatgagc attcagcctg ctgaagatcc    660

agatgattat gatgatggct tttcaatgaa gcatacagcc accgcccgtt tccagagaaa    720

ccaccgcctc atcagtgaaa ttcttagtga gagtgtggtg ccagacgttc ggtcagttgt    780

cacaacagct agaatgcagg tcctcaaacg gcaggtccag tccttaatgg ttcatcagcg    840

aaaactagaa gctgaacttc ttcaaataga ggaacgacac caggagaaga agaggaaatt    900

cctggaaagc acagattcat ttaacaatga acttaaaagg ttgtgcggtc tgaaagtaga    960

agtggatatg gagaaaattg cagctgagat tgcacaggca gaggaacagg cccgcaaaag   1020

gcaggaggaa agggagaagg aggccgcaga gcaagctgag cgcagtcaga gcagcatcgt   1080

tcctgaggaa gaacaagcag ctaacaaagg cgaggagaag aaagacgacg agaacattcc   1140

gatggagaca gaggagacac accttgaaga aacaacagag agccaacaga atggtgaaga   1200

aggcacgtct actcctgagg acaaggagag tgggcaggag ggggtcgaca gtatggcaga   1260

ggaaggaacc agtgatagta acactggctc ggagagcaac agtgcaacag tggaggagcc   1320

accaacagat cccataccag aagatgagaa aaaagaataa gtgttgcctt gttttgtgtg   1380

ttctaaatac tttttttaat gaaaaaatgt tttttggttt taatggtgtt acgtggtttg   1440

tgtattaatt ttttttcttg tccatatcac accaccaaag gcttttggac catttagcat   1500

catgagccta atggctcagt cagtcacctt tcttaagtgt tgtgaagatg gctcttttct   1560

ttggatcttg tttctagccc tcaactgctg aaagcctcag aatttagatt aattgagaaa   1620

acacccacct cttttagaga attatccttt gatgctgcag aatctactct tacaatgcct   1680

tcctacagct cactggggtg cttaccaaag ccatagcttt aaaccttccc agtccccatc   1740

agtagcttcc tgaaagtctc ctctcttgtt tacttctgca aagggtagct tcttaaaaac   1800

gtgatcatgt atgagtatgt atttgttcac ttaccctttt ttacttttaa tcaatgtcag   1860

ataccaagag ttgtgttaag ctgagtgtag tgtgtaacta actacacttg gatcttactg   1920

atccagaaat agtccccata gttagagtag ttacttatga agtggttatt aaagtgaaca   1980

cagcacatat acattatcta tactgctttt tgttatgatt aatactgggt atgttctggt   2040

aaatccatcc ttattgtata gaaaaaaaat tactttttta ccaggttttc caaagacaga   2100

atagatcaca aagctcaagg aatttaatat tcttgtaatg gactagataa ttcaaactga   2160

ttagcccatt ccagaagaaa aacagctggg aattaagtta atccacttga aattgtttta   2220

caataatcag aacatccaaa cctcaaggct caggatccca tagaccagag cccacctttt   2280

tgataaactt agtaaagtct tggagactag aagcaagata gtttgtgaca cataagcttc   2340

ccaaaaacta gaatagattt ttactgaata gtggtatatc tgatggtata tgtttcttaa   2400

aggtccaaat gtaataaaaa aaaaa                                         2425


<210>  580
<211>  4441
<212>  DNA
<213>  Human

<400>  580
ggcttagccg ccaccgcgcg cttcggaagg ccagagggag ggggaggcct gtcagtctcg     60

cgcgttgcct gggcgaaggg ggcggagctt tggcgtgggg cggccaatag tgggggtggc    120

tgcgtgggtc gccatgggga cggggctgtt cccggggagg ctgtgatggg ttgacaggtg    180

cgtgacagtg ggagctgctc tcggcacaag catgtacggc aaaggcaaga gtaacagcag    240

cgccgtcccg tccgacagcc aggcccggga gaagttagca ctctacgtat atgaatatct    300

gctccatgta ggagctcaga aatcagctca aacattttta tcagagataa gatgggaaaa    360

aaacatcaca ttgggggaac caccaggatt cttacattct tggtggtgtg tattttggga    420

tctctactgt gcagctccag agagacgtga aacatgtgaa cactcaagtg aagcaaaagc    480

cttccatgat tacagtgctg cagcagctcc cagtccagtg ctaggaaaca ttcccccagg    540

agatggcatg ccagtaggtc ctgtaccacc agggttcttt cagcctttta tgtcacctcg    600

gtaccctgga ggtccaaggc ccccattgag gatacctaat caggcacttg gaggtgtccc    660

aggaagtcag ccattactcc ccagtggaat ggatccaact cgacaacaag gacatccaaa    720

tatgggtggg ccaatgcaga gaatgactcc tccaagagga atggtgccct taggaccaca    780

gaactatgga ggtgcaatga gacccccact gaatgcttta ggtggccctg gaatgcctgg    840

aatgaacatg ggtccaggtg gtggtagacc ttggccaaac ccaacaaatg ccaattcaat    900

accatactcc tcagcatctc ctgggaatta tgtaggtcct ccaggaggtg gagggccacc    960

aggaacaccc atcatgccta gtccagcaga ttcaaccaac tctggtgata acatgtatac   1020

tttaatgaat gcagtacctc ctggacctaa cagacctaat tttccaatgg gtcctgggtc   1080

agatggtccc atgggtggat taggaggaat ggagtcacat cacatgaatg gctctttagg   1140

ctcaggagat atggacagta tttccaagaa ttctcccaat aatatgagcc tgagtaatca   1200

accgggcact ccaagggatg atggcgaaat ggggggaaat ttcttaaatc cttttcagag   1260

tgagagttac tcccctagca tgacaatgag cgtgtgatcc attaccaagt ctcctcatga   1320

aaaccacagt gagtcagccc ttcacagaac tactacggaa gaaaattatt catcacagtg   1380

tacagttaaa caaaggaatc tcagtcacac caaaccaacc tttttatttc ctgctctctc   1440

ccctcttttg tgaagaaagc gggtccaaat gtgattcaaa caactgtacg gagtggcata   1500

ttagaattgc cctaaactga actgcaaata attatgtgtg tatgtatatg tgtgggaaag   1560

agaatgtact gtatatgtgt atgttataca gacatataca catacataca ttgacccaca   1620

ggacattgta aaatattatc acatgacatc ttaagtagaa ataagtaggg acttttattc   1680

catccttttt ttcacgttta cattttaatt attacaagtt gctcctgccc cctccctgaa   1740

ctattttgtg ctgtgtatat cactgcttta tataagttat tttttaaggt gaactcagat   1800

gttatggttt tgtaaatgtc tgcaatcatg gataggaata aaatcgctta tttgagagct   1860

ttcattaaat tgcgtctgat gcaagttatc ctgtgaatca caaagtgtac tgtctcaaaa   1920

aatagaagaa aatgtgtctt cgtctttatg ttgaatcaaa caatttctca gttaccttca   1980

gtgaaaagta tttttttaat ttttatttga gaaaaacact tcaaatcagt aaaagcttaa   2040

ctggggcctc acacagtata tttctgcaat aactgcttta aacggagttc ttgatttgtt   2100

tgtcttagat gatacagaaa tcattaaata gcccaaatca tttagaccat agcaataaag   2160

tgaccggggt tgtcatatat ttagcaacat cttttctctt taacatgatg aagcccaaaa   2220

gtgataacaa aagcatttgc ttgaatttgt cacttctcac caggagtact agaggtaaat   2280

ttttaataac atactaatgt gaaatggtat ctggttttta ttcagacttt ttgtgagcat   2340

attcttatag acactagaaa taaatacata gaaggagact ttgagcacaa gggagaagag   2400

agttattagc actcctgagg cctctggaat gctgcttttc tatccaggta tcttgcttgc   2460

taccagcaga attgactggt attggttctc actggccagg gagcctctgc tctgttcctg   2520

gaatataagg cttttattca ggagcaaatc attgatagta actttgcttt atctagccat   2580

tgacttcagc aggctaaaac tacattgtgt aactgactgt tcaaaaaaga ataagtaaat   2640

tttttttaat ctaattccct tatggaaagc accttgctct atggcacttt ccagatcttt   2700

tgggattttg tgcttaatta tacatacata caccaaaatc acaatagaaa gatatgaaga   2760

ctttaatttt agactctgaa agataactgg gtgatccttt gtgttaaaat tgtgatacaa   2820

acaaccattg ataaatacca actatgaatc caaactctag agactttgaa aagcattgtt   2880

taattgcagg taagaggaat cttctctttc ctttaggctt atagtctcta aagtgaaaat   2940

ttggcaggat atagtcatgc agctcataat gacattccaa tcaaccacag actgcatata   3000

cagcagtggt cctataagat tataatacca tatttttagc atatcttttc tatgcttaga   3060

tacacaaata ccattgtatt acagttgcct ttggtattca gtacagtaac atgctgtaca   3120

ggtttgtagc ctaggagcaa tagtttatat tatatagcct aggtgtgtag gagcctatac   3180

catctaggtt tgtgtaagta cactctatga tgttcagaca aggacaatat tgcctgacaa   3240

tgcatttctc agaatgtata cttatcatta agtaacatat gactgtatgt actagttcct   3300

gatgacttac ttctctcaaa ttcataatga tttagtcctt gtaaaaataa agattttgcc   3360

tgtgcctaaa cagggatact aggcagaact gttgagaaaa aaaagctgaa ttaaatttat   3420

gttgcagatt taaactatca taaaatgagc ctcagttaat cacacacagt attcaggtgc   3480

ctaggagtgc acaccggaga acagcctcat gctgtcaagc tgcagaaacc tttcatgcaa   3540

attcagatga aaaggtcttt acctcaagcc agggtaacct gaatgaaggt gatagtttgt   3600

ccagacacct gactttacca agaagaattt tgactttcat attttatgac aatcatataa   3660

aaattgacag tcctttgatt attaagctta atcttataat gctagaattt tcaaatattt   3720

tgttgactct tctccattgt taccgatctt gaaattcttt tcttcgcctt ctgagaaggt   3780

attatttctt atcacaaaga atgatgaata tgattttatc tacccttatt ttgggggtaa   3840

tacgagaata tgaattgcat catgatcccc attatttcta acctaaaagt aaaattcgtt   3900

ttttttttca aggcagagca gtcaattgat tataagtatt tatttctttt ttcttcttgg   3960

agcccagatt aaaaagagtt attttagatt taaaaatttc ctgaaatagt tgaaaaatta   4020

tttttgagga gaaaattgta tccaagaaac ccagaatgta aggatacttg atttttatat   4080

ccagataatt ctttcatgca ctgaatggaa gacagtatat ctgtatatta atttttgttt   4140

agattttgaa tcatttaacc cttatccttt tttcttgtaa taagactatt taatgttttt   4200

ctcttgtgtt ttccatcttt atcaatgcat tcgtgttggt cttgatgtat actacctgtt   4260

cctagtgtta tttttacacg tcatctcaca gtaataatat cagcaattct tgctgcattg   4320

aacatattaa atacacatgt aaaatgaaaa agtaagcagt aggtaaaatc ttgttactct   4380

gctttgcatt ctgcctaact cactgcattt gaaaatacat gtcaaattct ttctgagggt   4440

a                                                                   4441


<210>  581
<211>  11650
<212>  DNA
<213>  Human

<400>  581
atggtggccc tgtccttaaa gatttgtgtg cgccactgca acgtggtgaa gaccatgcag     60

tttgaaccat ctacagctgt gtacgatgcg tgtcgagtca ttcgggaacg ggtgcctgag    120

gcacaaactg ggcaagcttc tgactatgga ctctttcttt cggatgaaga cccgaggaaa    180

gggatttggc tggaagcggg cagaacactg gattactaca tgttgcggaa tggggatatt    240

ttggaatata aaaagaaaca gagacctcag aaaatccgga tgctggatgg atctgtgaag    300

acagtgatgg tggatgattc caagactgtg ggggagctcc tggtcactat ttgtagcaga    360

ataggaataa caaattatga agaatactcc ttaatccaag aaactattga agaaaagaaa    420

gaggaaggaa cgggcacact caaaaaagac aggacactgt tacgagatga gaggaaaatg    480

gagaagttga aggccaagct gcacacagat gatgacctaa attggctgga tcacagccga    540

acattcagag aacaaggagt agatgaaaac gaaacgttgc tgcttagacg gaagttcttt    600

tactctgatc agaatgtaga ttcgagagac cccgtgcagc tgaacttgct ttatgttcag    660

gcacgggatg acatcctgaa tggctctcac cctgtctcct tcgagaaagc ttgtgagttt    720

ggtggatttc aagcccagat acaatttgga cctcatgtgg aacataaaca caaacctgga    780

tttttagatc tgaaggaatt cctgcccaaa gaatatatca agcagagagg agctgaaaag    840

aggatctttc aggagcataa gaactgcgga gagatgagtg agatagaagc caaggtcaag    900

tacgtcaaac tcgcacggtc cctccgcaca tatggcgtgt ccttcttcct ggtgaaggag    960

aagatgaaag gcaagaacaa gctggtgcct cgcctgctgg ggatcaccaa agactcggtg   1020

atgcgcgtgg atgagaagac caaggaagtg ctgcaggagt ggcccctcac caccgtcaag   1080

cgctgggcag cctcacccaa gagcttcaca ctggattttg gggagtatca ggaaagctac   1140

tattcagtac aaaccaccga gggagagcag atatcccagc tgattgcagg ctacattgac   1200

atcatcctga aaaagaaaca aagtaaagat cgatttggac tagaaggtga tgaggagtca   1260

accatgttag aagagtccgt ttccccaaaa aagtccacca tcttgcagca gcagttcaac   1320

cggaccggga aggcagagca cggctcagtg gcgctgccgg ccgtgatgcg ctcgggctcc   1380

agcgggcctg agaccttcaa cgttggcagc atgccctcgc cacagcagca ggtcatggtt   1440

gggcagatgc accgaggcca catgccgcca ctgacctcag cccagcaggc cctgatgggg   1500

accatcaaca caagcatgca cgccgtccag caggcccagg atgatctcag tgagctcgac   1560

tcgctgccac ctctcggcca ggatatggca tctagggtat gggttcagaa caaagtcgac   1620

gaatccaaac acgaaatcca ttctcaagtt gatgctatca cggccggaac ggcttcagtt   1680

gttaacctca cagctggtga ccctgcagac actgactaca cagctgtggg atgtgcgatc   1740

accactattt cttccaacct gacggagatg tccaagggtg tgaagctatt ggccgccctc   1800

atggatgatg aggtgggcag cggggaggac ttgctcagag ctgccaggac cctcgctggg   1860

gcggtgtcag acttgctgaa agctgtgcag cctacttctg gagagcctcg acagacagtt   1920

ttgactgctg ctggcagcat cggacaagcc agtggggatc ttctgagaca gattggagag   1980

aatgagactg atgagcgatt ccaggatgtt ttaatgagtt tggccaaagc tgttgccaat   2040

gcagctgcca tgttggtact aaaggcaaag aatgttgccc aagtggccga agacactgtc   2100

ctacagaaca gggtaattgc tgctgccacc cagtgtgccc tctccacctc ccagcttgtg   2160

gcatgtgcca aggttgtgag ccccactatt agctcccctg tgtgccagga gcagctgatt   2220

gaagcaggga agctggtgga ccgctcggtg gagaactgtg tccgtgcctg ccaggcggcc   2280

actaccgata gtgagctcct gaagcaggtc agcgcagcgg ccagcgtggt cagccaggcc   2340

ctccatgatc tcctgcagca tgtgcggcag tttgccagcc gaggcgagcc catcggccgc   2400

tacgaccagg ctactgacac catcatgtgt gtcaccgaga gcatcttcag ctccatgggt   2460

gacgctggtg aaatggtgcg ccaggcgcgg gttctggccc aagccacatc agacctcgtc   2520

aatgccatga ggtcagatgc agaagccgaa atcgacatgg agaattcaaa gaagctcctg   2580

gcagcagcaa aactcttagc tgactccact gctcgcatgg tggaagctgc aaagggggct   2640

gcagccaacc cagagaatga ggaccagcag caaaggctga gagaagctgc agaaggcctc   2700

cgggtagcaa ccaacgcagc tgcccagaat gctattaaga aaaaaattgt caaccgactg   2760

gaggttgcag ccaagcaggc cgcagcggca gccacacaga ccatcgccgc ctcccagaat   2820

gcagctgttt ccaacaagaa ccctgcggcc cagcagcagc tggtccagag ttgcaaggca   2880

gtggctgatc acatccctca gctggtccag ggagtgaggg ggagccaagc tcaagctgaa   2940

gacctgagtg cccagctggc tctcatcatc tccagccaga acttcctcca gcctggaagc   3000

aagatggtgt cctctgccaa agccgcagtg cccaccgtga gtgaccaggc cgcagccatg   3060

cagctgagcc agtgtgccaa gaacctggcc accagcttgg cggagctgcg taccgcctcg   3120

cagaaggccc atgaagcttg tggtccgatg gaaatcgatt cagctctgaa tacggtgcag   3180

acgcttaaga atgaactgca ggatgccaag atggcagccg tggagagcca gctgaagcca   3240

cttccagggg aaacgctgga aaaatgtgct caggacctgg gaagcacatc caaggcggtg   3300

ggctcctcca tggcacagct gctgacctgt gctgctcaag gcaacgaaca ctacacaggg   3360

gtggctgcta gagagacggc ccaagctctg aaaacactgg cccaggccgc ccgtggagtg   3420

gctgcatcga caaccgaccc cgcggccgcc catgccatgt tagattctgc tcgagacgtg   3480

atggagggct ccgccatgct cattcaagag gccaagcagg ccctgattgc acctggagat   3540

gcagagcgtc aacaaagact ggctcaggtg gctaaagccg tctcacactc cttgaataac   3600

tgcgtaaatt gcctccctgg gcagaaggat gtggacgtgg ccttgaagag catcggggag   3660

tccagcaaga agctgcttgt ggattcgcta cctccaagca cgaagccttt ccaggaagcc   3720

cagagtgaac tgaaccaggc agcagctgat ctgaaccagt ctgctgggga agtggtccat   3780

gccacccggg gccagagtgg agagttggct gcagcctctg gaaagttcag tgatgatttt   3840

gatgaattcc tcgatgctgg cattgagatg gctggccaag ctcagacaaa agaagaccag   3900

atccaagtga tagggaacct caagaatatc tcgatggcat ccagcaagct gctgttagct   3960

gccaagtctc tctctgtaga tccaggagct cccaatgcga aaaatctcct ggctgcagct   4020

gcaagagctg tgacagagag catcaatcaa ctcatcactc tgtgtaccca acaagctccg   4080

ggccagaaag agtgcgataa tgccctgcgg gagctcgaga ctgtgaaggg gatgttggac   4140

aatcctaatg aacctgttag tgacctctct tactttgact gcattgagag tgtgatggaa   4200

aactccaagg ttctgggtga atcgatggca gggatttcac agaatgccaa gaccggagac   4260

ctccctgcct ttggggaatg tgtggggatt gcatccaagg ctctctgtgg gctgacagag   4320

gctgcagccc aggctgcata cttggttggc atctctgatc caaacagcca ggcaggccac   4380

cagggcctgg tggaccccat ccagtttgcc agggctaacc aggccatcca gatggcatgc   4440

cagaacttgg tggaccctgg cagcagccca tcacaggtcc tgtcagccgc cacaattgtt   4500

gccaagcaca cgtcagcctt gtgcaatgcc tgccgcatcg cctcatccaa gacggccaac   4560

ccagtagcca agaggcactt cgtccagtca gccaaggaag tcgccaacag cactgccaac   4620

ctggtgaaga ccatcaaggc cctggatggg gatttctctg aagacaaccg caataagtgt   4680

cgcatcgcca ccgcaccctt gattgaagct gtggagaacc tgacagcgtt cgcctcaaac   4740

cctgagtttg tcagcattcc tgcccagatc agctccgagg gttcccaggc acaggaacca   4800

atcctggtct cagccaagac catgctggag agttcatcgt acctcattcg cactgcacgc   4860

tctctggcca tcaaccccaa agacccaccc acctggtctg tactggctgg acattcccat   4920

acagtgtccg actccatcaa gagtctcatc acttctatca gggacaaggc ccctggacag   4980

agggagtgtg attactccat cgatggcatc aaccggtgca tccgggacat cgagcaggcc   5040

tcgctggccg ccgtcagcca gagcctggcc acgagggacg acatctctgt ggaggccctg   5100

caggagcagc tgacttcggt ggtccaggaa atcggacacc ttatcgatcc catcgccaca   5160

gcggctcggg gagaagcagc tcagctggga cataaggtga cacaactggc aagctatttt   5220

gagcccttga tcttagccgc agttggtgtg gcctccaaga ttcttgatca tcagcagcag   5280

atgacggtgc tggaccagac caagactctc gcagagtctg ccttgcagat gttgtatgca   5340

gccaaagaag gtggcggaaa ccccaaggca caacacaccc atgacgccat cacagaggcc   5400

gcccagttga tgaaggaagc cgtggatgac atcatggtga cgctgaacga agctgccagt   5460

gaagtggggc tggttggggg catggtggac gccattgcag aagccatgag caagctggat   5520

gaaggcactc ctccagaacc aaagggaaca tttgtcgact atcagacgac tgtggttaaa   5580

tactccaaag ccattgcggt gacagctcag gaaatgatga ctaagtcggt tactaacccg   5640

gaggagttgg gaggactggc ttcacaaatg accagtgact atgggcacct ggctttccag   5700

ggccagatgg cagcagccac ggcggaacca gaggagatcg gattccagat tcgcactcgt   5760

gtgcaggacc tgggccacgg ctgtatcttc ctggtgcaga aggcaggggc cctccaggtc   5820

tgccccacag acagctacac caagagggag ctgatcgaat gcgcccgtgc cgtcacggaa   5880

aaggtctcct tggtgctctc ggctctccag gccgggaaca aaggaaccca ggcatgcatt   5940

acagccgcca ccgctgtgtc tgggatcatt gccgacctgg acaccaccat tatgtttgca   6000

acagcgggga cgctgaatgc agagaacagt gagaccttcg cagaccacag ggagaacatt   6060

ctcaagacgg ccaaggcctt ggtagaagac acgaaactac ttgtgtcagg agctgcgtcc   6120

actcctgaca agctggccca ggcggcccag tcctcagcag ccaccatcac ccagctcgca   6180

gaagtggtca agctgggggc agccagcctg ggctccgacg accccgagac ccaggtggtt   6240

ttgatcaatg ccatcaaaga tgtggccaag gccctttctg atctcatcag tgctaccaag   6300

ggagctgcca gcaagccagt ggacgaccct tccatgtacc agctcaaggg ggctgccaag   6360

gtgatggtga ccaatgtcac ctcgctcctc aagactgtaa aggcagtgga ggatgaggcc   6420

acccggggca ccagggcgct tgaggccaca attgaatgca taaagcagga gcttacggtg   6480

ttccagtcaa aagacgtacc tgaaaagaca tcatcacctg aagaatccat aaggatgacg   6540

aaaggcatca ccatggcaac agccaaagcc gtggcagctg ggaactcatg tagacaggag   6600

gacgtgattg ctactgccaa cctgagccgg aaagccgtgt cagatatgtt gacggcttgc   6660

aagcaagcat ccttccaccc cgatgtcagt gacgaggtga gaaccagagc cttgcgtttc   6720

gggacggagt gcacccttgg ctacttggac ctcctggagc acgtcttggt gattcttcag   6780

aaaccaaccc cagaattcaa gcagcagctg gccgctttct ccaagcgagt cgccggcgct   6840

gtgacagagc tcatccaggc ggcggaagcc atgaaaggaa cagagtgggt ggatccagaa   6900

gacccaactg tcattgcaga aacagagtta ctgggggctg cagcatccat cgaagctgct   6960

gctaagaagt tagagcaact gaagccaaga gcaaaaccaa aacaagcgga tgagaccctg   7020

gactttgagg aacagatctt ggaagctgct aaatccattg ctgctgccac aagcgccctg   7080

gtcaaatcgg cctcagcagc ccagagggag ctggtggccc aaggaaaggt gggctccatc   7140

cctgccaatg ctgcagacga cggacagtgg tcacaggggc tgatttctgc tgcccggatg   7200

gtggcggctg cgaccagcag tctctgtgag gcggccaatg cctccgttca gggacacgcc   7260

agcgaggaga agctcatctc atctgccaag caggtcgccg cttccacggc tcagctgctg   7320

gtggcctgca aggtgaaggc cgaccaggat tcagaggcca tgaggcggct acaggcggca   7380

ggaaatgctg tgaaaagagc ctcagacaat cttgtccgtg cagcccagaa ggcagctttt   7440

ggcaaagctg atgacgacga tgttgtagtg aaaaccaagt ttgtgggggg cattgctcag   7500

atcatcgccg cccaggaaga aatgctaaag aaagagcgag aactggaaga agcaaggaaa   7560

aaactggccc aaatccgcca gcagcagtat aagtttttac ccaccgagct gagggaagat   7620

gagggctaaa ggtgcgagcc cagatggcga gccccagggg atggccctgg ctgaactgga   7680

cagacagtgt tcctgagagg ctgggcactt agctggaaac cgcccacctc cctcccgggt   7740

gagcctggag ccctgcgtgc ttgttctcac atctctgtcc cgtcggcact ggctgcatga   7800

tcgtgatgtc acacggtaca atgtcctacc cacaactcct ctgccgcctc ccctcatgcc   7860

tcaccgtgtc tcaggagaga ggggtgcacg tttcatggac tgttaccaac aaagaaaagt   7920

cagtattatg ttgttctcag acactttggc ttttgttggt ccttctctta ggcctgctcc   7980

tggacctctt tatgatattg tgatagggaa aaaaatcatt gacgtcatag aatattcttc   8040

ttcctctcag gagaagacgg aagctggagt tggacatggt tcataaaagc cagaaacaca   8100

aacccgtgtg gactccggga gggtgactca ggtcctcctt ccatgtcttg agcactggct   8160

cacccagggg gtgaaaaatt cccgcccctg tttgcacgct ttcttgcctc cgtgtgtaag   8220

ctccttgtac aacccagacc catcttgtat tttgtggccc agaaaactga acgattattt   8280

tgttcctccg tagtccaaag ggcagagttg cggaaggccg tcggggcttg gtgagcaggg   8340

gctgtaatac agtctgtggg ctccttaccc tgcagaggct gtttcagctc acacagagtc   8400

atccacacaa acccacggct cccagttgac agtcagtgga atgctcgtct ccttagcgtc   8460

cagggtgggg attctgctgg aataaagagc ttcctcagtg actcatcttt aggtcccacg   8520

ctggtttctg tgccttcaga atggtcacaa gcccggattg gaaaggatct gcttacaaac   8580

ctgtcccctg tcctccaacc caaaacgcct ttttttctgt cttaatatcc agaaaatcta   8640

aatgcatcct aaaatcaatg tgaaccttta acaagatagt tttacttatt atcacataag   8700

acataagatg ttttcatttt ctggatgtca cacttccaga atttcatatt tttcccctct   8760

tttctttccc cttttcagag ccctcccata ggaagggaag ggcttgaatt tacccttaat   8820

ctgcaccttt agccaaggca gtgcatggaa gatgaatggc tcgtgggaca gaatctaatg   8880

ccagggagca ggagtgtttg aaagaattca tagtggggaa ggtaaaagtt aatggaagta   8940

catgattttc aaaactggta acagttaaag gcactcaccc tccgcctctc tctctctctc   9000

tctctctggt gtgctatcat gtcttggact ccatccacac tatagtttca aagttccact   9060

gacgggggaa agttggtgct ttggtcctcc gaagatgtca cctttcgacc ttgcccgatc   9120

ttgtttcacc agactctagc ccatgtcatg gttttaaaat acataaactt ctgacagctt   9180

cccatattta taagttactt ataagtgctg cacgtattag aatttttttt tttcagacca   9240

gtaaagttag agaaaagacg ctgtaaagga aaagcaagtg agagtatgtg taggacactg   9300

acagtgtgtg ggcaccagtt ctgaagagga ggggagctgc tggagcccta gcctgttggg   9360

gaaaagctgg cacactcttg gctcgccctc tttgagtgga gctgatccaa cacctcatgc   9420

ctgccttggc cggacactga gaggaggggc acacgtgctt ccagagacac tcaggagtca   9480

gaccccaatg ctcagagtca caatgtgttc atggcctcct gtaacaggac tctggggatc   9540

ccctctgtgg cccagcccac cccaccctct gctcttctat gctgtgccca gggcagctgc   9600

cctcttctgc ctgtgcccca tcccatcctg aaaacccagg accaaggcag gggcaggcag   9660

ccagttcttc caccttgcct cagagtcatt taaaaccttt actgcatttg ataccagaaa   9720

agcctccaga gacaaaccaa atgcaaaggc ctttccttta taactctaaa gaacaggcat   9780

cgaaagttta tttttgtagg agctatataa atactcacct ttctggagtc gtccagtgct   9840

gggagctttg gggagtttgg ttctcagtta tcacctggta tggtcccagt ttctcatctg   9900

tcctttcctc atccaccctg cacatgtgta tgtgaacggc ttcgtggccg gtgtggtggt   9960

ttctcatttc ataagatagt tgaagggcca tgccttgtct ggatgttatt taataggcac  10020

tactgcggtg tcctcagatg gtactgaggg ggccttctgg tccttcaaag gaaaataaca  10080

caggcatgag ttcatttggg agtgtgaact ttcagaacac ctaataagag agtggtgtca  10140

gagtaaaaac ggccccaggt ctggagcata gaagtgtatc tctgtgaaga gagagccggt  10200

gtgttgacat gtggttcttc tcacacccct ctactcctcg agggctttga atccttgggc  10260

tgatttttgt gccagaaatt gctgttcccg atggccaaaa ggggaacctg aactggattt  10320

cagaactgcc cagtgatttg aaaatttaga ttttacttgg gcctttcagg agtctttaga  10380

tagggatgct gaggtcatat ttagttcaat gaacagccct tgtttaagtt ttgccagtgt  10440

ccagccagct gtggccctgg ccatctgtgc aggcaggttc ctcaattcct ggttggccct  10500

gcagtcggtc aacacagtcc ctccaggtcg gctgcagagg cagctgccca gcctgcagtc  10560

tatgcacggg ccttaagaaa tgagctgcct gtagcctcac ggcatatgct tttatcaggg  10620

aaaacccttc gagcttcttc tgattctcac ctgcttgctt tctggctgtc ttagtcagtg  10680

tgtttacagg caactaaagc ctgttcctaa tttatcaaaa aattataacc aaaattcacc  10740

atagcctaag agagtaaacc ccacctccaa agtgatgcca aggccaaaac ctcatcaagg  10800

aaccagacac aggtcaaaag tggtgagcaa gccatggtct ctgctcctgg ggaactcaca  10860

cgctgacccc cgaggagcct tggtttcctc cctggcagat agtccccaga atcttctctc  10920

ccagctttga ggttctgggc tctggaaagg cctctgggat gctggcctta agatctcagc  10980

acagactatc agcatgttcc attctcagat tcctggagga aaggtaccct ctgttgacca  11040

aggggctggc tgcttctgag acttaccaac ccaagaaatt tggagacatt cccctcaggc  11100

taaaaggcag cggtccccag agttcagaaa gcaaaagatc ttgacaactg tgccagtagt  11160

ggctctggtc ctatctctcc acagtgctgg cctctgctgg ggaaggcatc tttcccaaag  11220

gtatccccaa gtaccatgtt gaaaatgtcc tcagtctgtt gctccatctt tctgagcctc  11280

tgcttggtat gtcatgttta tggtcactac ggatgagtgt gtgcagagtt tgggttgatt  11340

cttttaaatg ctacaaacaa gagctatttc ttttcaataa aaaaggtttg gattcggcct  11400

cttcctctga gcccacctcc cagccctcca gggagcatca gtgtacctga gtcactttgt  11460

ctgcatctct tcatcccaca aaacacgagg ctgggtctca ttcagcggcc tctcaccaac  11520

cttcaagatc cagaagaaaa caggaacgtt cagctctgcc ctgtgtcgta tctaatcaca  11580

tacattaatt tatctaacca cataagttat ttttttttat ttgccagaaa taaaccttta  11640

aaggaacaaa                                                         11650


<210>  582
<211>  1146
<212>  DNA
<213>  Human

<400>  582
ggcggagccg cctgggctgc agtcccaccc gggagccggc agggagcgga gctgcggagc     60

cgcctggtct cccgcgtcca tcggtccatt cctgcgtcgt tctgtccttc cgaacgcaca    120

cttcaggagc agccgcgagg agtgagcact gcacgcagga tccgcccagt gcttgggcca    180

agcaccctgt ggcatccaag ctcccctgga cgttaccctt ggtgaaccaa ggtggcatgg    240

cagcgagcac agacatggct gggctggagg agagcttccg caagtttgcc atccatggtg    300

accccaaggc cagtgggcaa gagatgaatg gcaagaactg ggccaagctg tgcaaggact    360

gcaaggtggc tgacggaaag tccgtgacag ggaccgatgt ggacatcgtc ttctccaaag    420

tcaaggggaa gtctgctcgg gtcatcaact atgaggagtt caagaaggcc ctggaagagc    480

tggcgaccaa gagattcaag gggaagagca aggaggaggc cttcgatgcc atctgccagc    540

tggtggcagg caaagagcca gccaatgtgg gcgtcactaa agcaaaaaca gggggtgctg    600

tagaccggct gacggacacc agcagataca cgggctccca caaggagcgc ttcgatgaga    660

gcggcaaggg caagggcatt gcgggacggc aggacatcct ggacgacagt ggctacgtga    720

gcgcctacaa gaatgcaggc acctacgatg ccaaggtgaa gaagtgaggc ttgggaagac    780

cgccctgcca agtgcggctg cccctgccag aggctcaggc ctgggtctaa ggggcacgtg    840

gagcaagaga tcctggtccc ctccctgctg gacctgccac ccagagcttc ctgcctagtc    900

ccactgggct ggcccaccag gcctctgacc caggctgctc tgcggcccct tcctcctcct    960

cttcctgctc caacttctgt ccacctgggg acagtctgtg cctgtagcct catgacccca   1020

acccagcccc aggcatggct aacccctgac tgcttgcctc atatttaagc tgctgctctg   1080

gccaagtgcc taattttaac ccagacctca ataaagacac cttttgtacc aaaaaaaaaa   1140

aaaaaa                                                              1146


<210>  583
<211>  1407
<212>  DNA
<213>  Human

<400>  583
gaccggagaa gctgtgaggt tctttagcgt cacctccctc actgggcagc atgggggaga     60

agtcagagaa ctgtggggtt ccagaggatc tgttaaatgg tttgaaggtt acagatactc    120

aggaagccga gtgtgctggc cctccagttc ctgatcccaa aaatcagcat tcccagagta    180

agctgctcag ggatgatgag gcccatctcc aggaggacca gggagaagag gagtgttttc    240

atgactgcag tgcctcattt gaggaggagc caggagcgga caaggttgag aacaaatcta    300

atgaagatgt gaattcctct gaactagatg aagaatacct aatagaactg gaaaaaaaca    360

tgtcggatga agagaaacag aaaagaagag aagagagcac tagactaaag gaggagggaa    420

atgaacagtt taagaaagga gattatatag aagctgaaag ttcttatagt cgagccctcg    480

aaatgtgccc atcctgcttc caaaaggaga ggtcgattct attttcaaat agagctgcag    540

caaggatgaa acaggacaag aaagaaatgg ccatcaatga ctgcagcaaa gcaattcaat    600

taaaccccag ctatatcagg gcaatattga ggagagcaga gttgtatgag aagacggaca    660

agctagatga agccctggaa gactataaat ctatattaga aaaagatcca tcaatacatc    720

aagcaagaga agcttgtatg agattaccta agcaaattga agaacgtaat gaaagactaa    780

aagaagagat gttaggtaaa ttaaaagatc ttgggaactt ggttctccga ccttttgggc    840

tctccacgga aaatttccag atcaaacagg attcctctac cggctcgtac tccatcaatt    900

tcgttcaaaa tccaaataat aacagataac aaagataaca aaagctttac aagctgactt    960

ggaattgtgt gctgcttgct gttagctagg ggaaaggccc tgccaatgtt taacttttaa   1020

aagcatctta tctaaaagaa aggctatcca gtagagccca gtgctccctt gtccctcttt   1080

tatgatcagg gtgaaatgta cttcctgatg taatgaacct aatttgattt ccattttaag   1140

gtggtgtctg tgcagctggt gtccccgatt ctggctgtcc tatgtccagg aagaagccca   1200

tttgttgagg ctgaccttcc tgatcataca cacacacagc ccagcaaaag cctctcctga   1260

accaaacaaa cctgttggtt gggagactgc ccagacatga ttgatgacgg gttcccgcct   1320

gctgtcccct ccctgatcac acagctaacg aggctgcctc cagcatttcc tgatttcctc   1380

tgtggtaata aaagctttct gtgctta                                       1407


<210>  584
<211>  3203
<212>  DNA
<213>  Human

<400>  584
gcagccccgc gagcaggcag cgccggcccc ccgccccgcg gccccgggcc ccggctccgg     60

cgccgtccct cctccccggc cgggcgccgc ggccccggca tgaggagcgg gcgatgatcc    120

ccgccaacgc ctccgccagg aaggggcccg agggcaagta tccgctgcac tacctcgtgt    180

ggcacaaccg ccaccgcgag ctggagaagg aggtccgcgc gggccaggtg gacatcgagc    240

agctggatcc ccgcggccgg actcccctgc acctggccac cacgctgggg caccttgagt    300

gtgcccgtgt gctcctggcg cacggcgcag acgtgggcag ggagaatcgc agcggctgga    360

cagtgctcca ggaggctgtg agtacccggg acctggagct ggtgcagctg gtgcttcggt    420

accgggacta ccagcgggtg gtgaagcggc tggcgggcat ccccgtgctc ctggagaagc    480

tgcgcaaggc ccaggacttc tacgtggaga tgaaatggga gttcactagc tgggtgcccc    540

tggtgtccaa gatctgccct agtgacacct acaaagtgtg gaagagcggc cagaacctga    600

gggtagacac cacactcctg ggctttgacc acatgacctg gcagcgaggg aaccgcagct    660

ttgtcttcag gggccaagac acaagcgccg tggtcatgga gattgaccac gaccgccggg    720

tggtgtacac agagactctg gcactggctg ggcaggaccg ggagctgctg ctggctgctg    780

ctcagcccac tgaggaacag gtgctgagcc ggcttaccgc gcccgtcgtc accactcagc    840

ttgacaccaa gaatatctcc tttgagagga acaagactgg catcctgggc tggcgcagtg    900

aaaagacgga gatggtgaat gggtatgaag ctaaggtgta tggggcatct aacgtggagc    960

tcatcacccg cacacggaca gaacatcttt cagaacagca caagggcaag gtcaaaggct   1020

gtaagacacc tttgcagtcc ttcctgggaa tcgctgagca gcacgggggc ccccaaaatg   1080

ggaccctgat cactcagact ctgagccaag ccaaccccac tgccatcact gcagaagaat   1140

acttcaaccc caactttgag ctgggcaacc gtgatatggg ccgccccatg gaactgacca   1200

ccaagacaca gaagttcaag gccaagctgt ggctgtgtga ggagcatccc ctgtccctgt   1260

gtgagcaggt ggcccccatc attgacctca tggccgtcag caatgcgctt tttgccaagc   1320

tccgggactt catcaccctg cgtctgcctc ctggcttccc agttaagatt gaaatcccga   1380

tcttccacat cctcaacgcc cgcatcacct tcgggaacct caacggctgc gacgaaccgg   1440

tgccatcggt gcgaggcagc cccagcagcg agacgccttc cccaggcagc gactcctcca   1500

gcgtcagcag ctccagctcc acgacctcct gccgcggctg cgagatctcc ccagcgttgt   1560

tcgaggcccc gcgcggctac agcatgatgg gcggccagcg ggaggcggcg acccgggacg   1620

acgacgacga cctgctgcaa ttcgccatcc agcagagcct gcttgaggcg ggcagtgagt   1680

atgaccaggt caccatctgg gaggcgctaa ccaacagcaa gccaggcacc caccccatgt   1740

cctacgaggg tcgccgacag gacaggagcg ccccgcccac gccgcagcgc cagcctgcgc   1800

ccccggcgtc agtgcccagc cctcggccca gctcagggcc aggttccggc ggccacgtgt   1860

tccggagcta cgacgagcag ctgcggctgg cgatggaact gtcggcgcag gagcaggagg   1920

agaggcggcg gcgcgcgcgc caggaggagg aggagctgga gcgcatcctg aggctctcac   1980

tgaccgagca gtagcgcccc ctgccgggac cctcgccagc gccacgcgcg ccacgcccag   2040

ggccaggagc cagacaaacc ccggcctgcg cgcctgcaga gcggcggctg gagactggag   2100

ccaccgcctc gcgggtgcag cagcacagca ggcacggttc ggggagggat tcggcatggc   2160

cgcggggtac cttcccaggc cagggccctg gaggcaactg gcacggcctg gtccccctgc   2220

tttgctgtat tctgattccc caacccgctc ccctgggctc agatctgtcc tgtcctaggg   2280

cggagccagg cggtcctgag ggggagatga atccttagag gagcgctgtc cctatccctt   2340

gctccttctg gccggtccgc atttctgttc actaacccca ctccaggaca ctgcccctga   2400

agcctttgca tctctgctct tcactcctgg ggggcagctg agctccccgc gtgctgtgtc   2460

actgctttgt tccagacaca aaccagcacg tctagggccc agcccctccc ccaccccggc   2520

atttcagcgt caagtgcact tagcggggta cccggctccc ccagccccca cacccgtcct   2580

gggtctcagg gtggttccag cttctccttg ggcagccaga agttggagtc ccatccccca   2640

aggcacattt tttttttttt ttttttgtga tcagggagtg tgtccaacgt agccccctgg   2700

cctgtgcaag ccctgactcc ctcatggtgc ctcggagagt ggggagcata ttgggctggg   2760

gtaagcacta gacccaagta gactggacac aaagggctcg cccagggccc tggcgccacc   2820

cccacccctt cccaccagct gctgctagcc tctgtggttg tacatcccac ttgcccccac   2880

acggagactg actctaaaac ccttcatcca atggtgctaa cccccggctc tcccctgccc   2940

cacctcaccc acccagagaa gcacagaccc cgccaggggc aggggcccac cgcacaccct   3000

tgtcccgggc ctgtctggga ctggccttcc cggctcagcc agtgaggctc agaagggaca   3060

caaagaggga tggaagaaaa gaacaaagag aaactgttcc tcccaccccc ttccctgatg   3120

ccaggggcac cagactgatt ctgaggcaca aataaaagag gcttcatacc ggaaaaaaaa   3180

aaaaaaaaaa aaaaaaaaaa aaa                                           3203


<210>  585
<211>  3433
<212>  DNA
<213>  Human

<400>  585
cggctcagag ctccggaccg cgggcggagg ggaggggcag ggggcggtgc cacggcctgc     60

cagcccgccc gcccgcccgc cagccagccc tccccgcggc cggctcggct ccttggcgct    120

gcctggggtc ctttccgccc ggtccccgct tgccagcccc cgctgctctg tgccctgtcc    180

ggccaggcct ggagccgaca ccaccgccat catgccggcc gtgtccaagg gcgatgggat    240

gcgggggctc gcggtgttca tctccgacat ccggaactgt aagagcaaag aggcggaaat    300

taagagaatc aacaaggaac tggccaacat ccgctccaag ttcaaaggag acaaagcctt    360

ggatggctac agtaagaaaa aatatgtgtg taaactgctt ttcatcttcc tgcttggcca    420

tgacattgac tttgggcaca tggaggctgt gaatctgttg agttccaata aatacacaga    480

gaagcaaata ggttacctgt tcatttctgt gctggtgaac tcgaactcgg agctgatccg    540

cctcatcaac aacgccatca agaatgacct ggccagccgc aaccccacct tcatgtgcct    600

ggccctgcac tgcatcgcca acgtgggcag ccgggagatg ggcgaggcct ttgccgctga    660

catcccccgc atcctggtgg ccggggacag catggacagt gtcaagcaga gtgcggccct    720

gtgcctcctt cgactgtaca aggcctcgcc tgacctggtg cccatgggcg agtggacggc    780

gcgtgtggta cacctgctca atgaccagca catgggtgtg gtcacggccg ccgtcagcct    840

catcacctgt ctctgcaaga agaacccaga tgacttcaag acgtgcgtct ctctggctgt    900

gtcgcgcctg agccggatcg tctcctctgc ctccaccgac ctccaggact acacctacta    960

cttcgtccca gcaccctggc tctcggtgaa gctcctgcgg ctgctgcagt gctacccgcc   1020

tccagaggat gcggctgtga aggggcggct ggtggaatgt ctggagactg tgctcaacaa   1080

ggcccaggag ccccccaaat ccaagaaggt gcagcattcc aacgccaaga acgccatcct   1140

cttcgagacc atcagcctca tcatccacta tgacagtgag cccaacctcc tggttcgggc   1200

ctgcaaccag ctgggccagt tcctgcagca ccgggagacc aacctgcgct acctggccct   1260

ggagagcatg tgcacgctgg ccagctccga gttctcccat gaagccgtca agacgcacat   1320

tgacaccgtc atcaatgccc tcaagacgga gcgggacgtc agcgtgcggc agcgggcggc   1380

tgacctcctc tacgccatgt gtgaccggag caatgccaag cagatcgtgt cggagatgct   1440

gcggtacctg gagacggcag actacgccat ccgcgaggag atcgtcctga aggtggccat   1500

cctggccgag aagtacgccg tggactacag ctggtacgtg gacaccatcc tcaacctcat   1560

ccgcattgcg ggcgactacg tgagtgagga ggtgtggtac cgtgtgctac agatcgtcac   1620

caaccgtgat gacgtccagg gctatgccgc caagaccgtc tttgaggcgc tccaggcccc   1680

tgcctgtcac gagaacatgg tgaaggttgg cggctacatc cttggggagt ttgggaacct   1740

gattgctggg gacccccgct ccagcccccc agtgcagttc tccctgctcc actccaagtt   1800

ccatctgtgc agcgtggcca cgcgggcgct gctgctgtcc acctacatca agttcatcaa   1860

cctcttcccc gagaccaagg ccaccatcca gggcgtcctg cgggccggct cccagctgcg   1920

caatgctgac gtggagctgc agcagcgagc cgtggagtac ctcaccctca gctcagtggc   1980

cagcaccgac gtcctggcca cggtgctgga ggagatgccg cccttccccg agcgcgagtc   2040

gtccatcctg gccaagctga aacgcaagaa ggggccaggg gccggcagcg ccctggacga   2100

tggccggagg gaccccagca gcaacgacat caacgggggc atggagccca cccccagcac   2160

tgtgtcgacg ccctcgccct ccgccgacct cctggggctg cgggcagccc ctcccccggc   2220

agcacccccg gcttctgcag gagcagggaa ccttctggtg gacgtcttcg atggcccggc   2280

cgcccagccc agcctggggc ccacccccga ggaggccttc ctcagcccag gtcctgagga   2340

catcggccct cccattccgg aagccgatga gttgctgaat aagtttgtgt gtaagaacaa   2400

cggggtcctg ttcgagaacc agctgctgca gatcggagtc aagtcagagt tccgacagaa   2460

cctgggccgc atgtatctct tctatggcaa caagacctcg gtgcagttcc agaatttctc   2520

acccactgtg gttcacccgg gagacctcca gactcagctg gctgtgcaga ccaagcgcgt   2580

ggcggcgcag gtggacggcg gcgcgcaggt gcagcaggtg ctcaatatcg agtgcctgcg   2640

ggacttcctg acgcccccgc tgctgtccgt gcgcttccgg tacggtggcg ccccccaggc   2700

cctcaccctg aagctcccag tgaccatcaa caagttcttc cagcccaccg agatggcggc   2760

ccaggatttc ttccagcgct ggaagcagct gagcctccct caacaggagg cgcagaaaat   2820

cttcaaagcc aaccacccca tggacgcaga agttactaag gccaagcttc tggggtttgg   2880

ctctgctctc ctggacaatg tggaccccaa ccctgagaac ttcgtggggg cggggatcat   2940

ccagactaaa gccctgcagg tgggctgtct gcttcggctg gagcccaatg cccaggccca   3000

gatgtaccgg ctgaccctgc gcaccagcaa ggagcccgtc tcccgtcacc tgtgtgagct   3060

gctggcacag cagttctgag ccctggactc tgccccgggg gatgtggccg gcactgggca   3120

gccccttgga ctgaggcagt tttggtggat gggggacctc cactggtgac agagaagaca   3180

ccagggtttg ggggatgcct gggactttcc tccggccttt tgtattttta tttttgttca   3240

tctgctgctg tttacattct ggggggttag ggggagtccc cctccctccc tttccccccc   3300

aagcacagag gggagagggg ccagggaagt ggatgtctcc tcccctccca ccccaccctg   3360

ttgtagcccc tcctaccccc tccccatcca ggggctgtgt attattgtga gcgaataaac   3420

agagagacgc taa                                                      3433


<210>  586
<211>  2358
<212>  DNA
<213>  Human

<400>  586
tttttttttt ttttttgctt aaaaaaaagc catgacggct ctcccacaat tcatcttccc     60

tgcgccatct ttgtattatt tctaatttat tttggatgtc aaaaggcact gatgaagata    120

ttttctctgg agtctccttc tttctaaccc ggctctcccg atgtgaaccg agccgtcgtc    180

cgcccgccgc cgccgccgcc gccgccgccg cccgccccgc agcccaccat gtctcgccgc    240

aagcaaggca aaccccagca cttaagcaaa cgggaattct cgcccgagcc tcttgaagcc    300

attcttacag atgatgaacc agaccacggc ccgttgggag ctccagaagg ggatcatgac    360

ctcctcacct gtgggcagtg ccagatgaac ttcccattgg gggacattct tatttttatc    420

gagcacaaac ggaaacaatg caatggcagc ctctgcttag aaaaagctgt ggataagcca    480

ccttcccctt caccaatcga gatgaaaaaa gcatccaatc ccgtggaggt tggcatccag    540

gtcacgccag aggatgacga ttgtttatca acgtcatcta gaggaatttg ccccaaacag    600

gaacacatag cagataaact tctgcactgg aggggcctct cctcccctcg ttctgcacat    660

ggagctctaa tccccacgcc tgggatgagt gcagaatatg ccccgcaggg tatttgtaaa    720

gatgagccca gcagctacac atgtacaact tgcaaacagc cattcaccag tgcatggttt    780

ctcttgcaac acgcacagaa cactcatgga ttaagaatct acttagaaag cgaacacgga    840

agtcccctga ccccgcgggt tcttcacaca cccccattcg gcgtagtacc cagagagctc    900

aagatgtgtg gcagttttcg gatggaagct cgagagccct taagttctga gaaaatttga    960

agcccccagg ggtggggtgg acgcgtgccg cccagtcgac gtcagcgtgg tctgtcatcc   1020

tgctagtttg tgatgttttc tgacagtagc ctccaagaag ccgttgtgcg aagacagagt   1080

cctgcagagt ccttccagcc taggcctgca gcgccatttt atttatattt tttaataaaa   1140

agtaaaaaca aaaaaacaga cccacattgg aacagtgaat cagtcccata gagagggccc   1200

gtggaccatc gctgtcatga gtgatgccct ggcccttctg aaaccagcca acctaattac   1260

ctgtattgtg gaaatgcgca tgagtcccca accccttgtt tctatacatt ctatgttgtc   1320

ttttaaaaag tgtgcttaac attgacacaa taaatgttgg agctttaggt ggtgtttgct   1380

tgttctttaa tttttaatgc ttataagaca atgaggctgc ttatgatttt gtacttctgt   1440

acctgtttcc tacagacacc catcgggtgg gtaggaggaa cagatttgag aaatgggcag   1500

gagatgtagg aggggaacta ggttaccgct tatcagatgg cataaatttt caaggagaat   1560

caaaatgcaa aacttgggaa taaatcatag caatatcata attaatgtag tagtaatatt   1620

gctgtttatt aatgctgaag tgtggttttc ctaactgtct gacttataat ttgcatacca   1680

ttaaataatg cataatatgg cacgccgaat cctgtttttc aaatatatgc ttttggtggc   1740

taccatgcag gatttgaatt tgtcttttaa tttagcttag gaaagaacat cactgggcga   1800

gcggtaaatc ctaaagaagg tgataaatgt cagtagtttc ttattaaata ttctaatttt   1860

aggttcccaa accttcagga aatatatctt aatgcagaca aacaaacata aaacttcttt   1920

agtacttaca tcaggaaatt tggggcagat tttagagggg ggaaattata ggaggaaaga   1980

agttcacatc agaacagaca atcacagcaa tgctctattc cttagaaatt agtgccacaa   2040

ataagttaca tctacaaaca ggtggtaaaa attctttctg gcccagttaa tttgcacaga   2100

acttttctca gtttggtatt ttttactgct tggagatcca gaagagaatt agaaacaaca   2160

tagcaaatta aaataggttt gtcaataata gagctcagac acctgtgtgc tgtagattca   2220

catacaggcc gtgaacctaa gtggggaaaa tcctacctat ccaccttctg gctagattac   2280

ctagcttagt gaaaagatag ccaaataatt ggcatgtgaa ttatttcctg cttattcata   2340

ataaataatg actgtcta                                                 2358


<210>  587
<211>  2947
<212>  DNA
<213>  Human

<400>  587
cctgtttgtc cgccactgtt tgaaaacagt tggcgccgcc gccgccgggg cctcatttcc     60

aggtcagccc ccggcctgac gcggcgttgc gtcccccggg agctgcgcta ggcgaacggc    120

tgcggcgctt tgtgctccag tcgctcctaa cgctccctgg cccggccggg gccgcgcagt    180

tagggcatct gaggcgggga gaagcggcgg ggagacgccg gctgccagca tgtcgctgcc    240

tccggagaaa gcctccgagc tgaagcagct catccaccag cagctgagca agatggatgt    300

ccatggtaga ataagagaaa tccttgctga gactatacgg gaagaattgg cacctgatca    360

acagcattta tcaacagaag atttgatcaa agcccttaga cgtcgaggaa tcattgacga    420

tgtgatgaaa gaacttaatt ttgttactga cagtgttgag caagaactcc cttcctctcc    480

aaaacaacct atttgttttg atagacaatc gacattaaaa aaaactaata ttgatccaac    540

acggaggtat ctttaccttc aggttttggg tggaaaagct ttcttggaac atctgcaaga    600

acctgagcct ttacctggac aagtttgttc aacgtttact ttatgtttac attatcgaaa    660

ccaacgtttt cgttctaaac ctgttccatg tgcctgtgaa ccagattttc atgatggctt    720

tttacttgaa gtacacagag aaagcttggg tgatggaact agaatggctg attcaacaac    780

aatgttatca ataagtgatc caattcatat ggtgctaatc aaaacagaca tatttggtga    840

gacgacttta gtagcatcat attttctgga atggcgatcg gttttgggct cagaaaatgg    900

agtgaccagt ctgactgtgg aacttatggg tgtaggcaca gaatcaaaag tttctgtggg    960

aattttaaat ataaaacttg aaatgtatcc accactcaat caaacgttat ctcaagaagt   1020

agtgaacaca cagcttgctt tggaacgtca gaaaactgca gagaaagagc gattatttct   1080

tgtatatgct aagcagtggt ggagagaata tttgcaaatt cgaccctcac acaactcacg   1140

actggttaag atttttgcac aggatgaaaa tgggataaat agaccagtct gttcctatgt   1200

taaaccactt cgagctggac ggcttcttga tactccaagg caagcagcaa gatttgttaa   1260

tgtccttggt tatgaacgag cccctgttat tggaggagga ggtaaacagg agcagtggtg   1320

cactctgctg gcctttctct gtagaaacaa gggtgactgt gaagatcacg ctaaccttct   1380

gtgcagcctt cttcttggat atggattaga agcctttgtt tgtgttggga ccaaggcaaa   1440

aggagtacct catgcatggg ttatgacttg tggaactgat ggggccatca ctttttggga   1500

gagtttaaca ggacacaggt acatccataa acctaccaat cctgatgaac ctccagttgc   1560

tgaacagccc aaaccactgt acccatatcg aacaattggt tgtgttttca accatcagat   1620

gttcctggga aattgtcaac cctctgatgc agtagaaacc tgtgtatttg atttgaacga   1680

tgaatccaaa tggaaaccca tgagtgagga agcaattaaa tctgtgtgtg ctcctggagc   1740

tacaacatcc cttcctccct ttccacctct gtgtgcatcc acaattgacg cgtcagtaac   1800

aagtaatgaa attgaaatgc agctgaggct cctggtgtca gaacacagga aggatcttgg   1860

cctcactact gtttgggaag accagctctc ctacctttta tcaccagctt tggcttctta   1920

tgaatttgag cgtacaacaa gtatatcagc aggcaatgaa gaatttcaag atgccataag   1980

aagggctgta cctgatggtc acacatttaa agggttccca atacattttg tgtatagaaa   2040

tgcaagacgt gcatttgcca catgtcttcg atctcctttc tgtgaagaaa taatctgttg   2100

ccgtggagac caagtgcgac tggcagttcg tgtccgagta tttacttacc ctgaatctgc   2160

atgtgctgtt tggatcatgt ttgcttgtaa atatcgctcg gtattatagg gccaatattt   2220

atataagatt tatacctgtg tttaattgga attttacaca ttgtacatta cttagctatt   2280

tagaggtttg ttattttaaa atcacaatct ggcttgaatg gcatacttca attttgtata   2340

tacttgactg gtaatgttta aaaaaaatca tgcattcctt taaaaattaa ggctgaaaaa   2400

cttgtataaa tctccctgga atttagtata aattaagtgt atattctatt ttaataaatg   2460

ctactttgtt tacagttatc agtagtttaa atattaatat aaaatgcatt cagttttctt   2520

tacacaaaca ggtaatcaaa gagatgtttg tctaagggtt tgagccctag acaaatcagt   2580

atgatcatta cttttcacag gttaatggaa ttattttata cagattagga gaaattaacc   2640

tcatgacaga tttatttatt gcattggtga aaataaatgt taatgaatta ccacttttgt   2700

ggtttattcg tggtccttgg gatatttgag actgtccaga aatttatggt tggaccttga   2760

agcaagagta ggaaaaaact aataccagaa aagcataaat attaataacc tcatatgaaa   2820

gtacatgaat catttagaaa tatttatcac tgtgatttgt tgtaaaaatg aattgggtat   2880

tttagaaaaa ctttattata cctctttgtt atgatactga taaattgtga tcttgcagtc   2940

gatcact                                                             2947


<210>  588
<211>  1397
<212>  DNA
<213>  Human

<400>  588
aggatgtgta gggggcgggg cccggcggaa gcgtatataa ggccgggctc ggggacgccc     60

ccccctcact cgcgcgttag gaggctcggg tcgttgtggt gcgctgtctt cccgcttgcg    120

tcagggacct gcccgactca gtggccgcca tggcatcaga tgaaggcaaa ctttttgttg    180

gagggctgag ttttgacacc aatgagcagt cgctggagca ggtcttctca aagtacggac    240

agatctctga agtggtggtt gtgaaagaca gggagaccca gagatctcgg ggatttgggt    300

ttgtcacctt tgagaacatt gacgacgcta aggatgccat gatggccatg aatgggaagt    360

ctgtagatgg acggcagatc cgagtagacc aggcaggcaa gtcgtcagac aaccgatccc    420

gtgggtaccg tggtggctct gccgggggcc ggggcttctt ccgtgggggc cgaggacggg    480

gccgtgggtt ctctagagga ggaggggacc gaggctatgg ggggaaccgg ttcgagtcca    540

ggagtggggg ctacggaggc tccagagact actatagcag ccggagtcag agtggtggct    600

acagtgaccg gagctcgggc gggtcctaca gagacagtta tgacagttac gctacacaca    660

acgagtaaaa acccttcctg ctcaagatcg tccttccaat ggctgtgtgt ttaaagattg    720

tgggagcttc gctgaacgtt aatgtgtagt aaatgcacct ccttgtattc ccactttcgt    780

agtcatttcg gttctgatct tgtcaaaccc agcctgaccg cttctgacgc cgggatggcc    840

tcgttactag acttttcttt ttaaggaagt gctgtttttt tttgagggtt ttcaaaacat    900

tttgaaaagc atttactttt ttgaccacga gccatgagtt ttcaaaaaaa tcgggggttg    960

tgtgggtttt tggtttttgt tttagttttt ggttgcgttg cctttttttt tttagtgggg   1020

ttggccccat gaagtgggtg ccccactcac ttctctgaga tcgaacggac tgtgaatccg   1080

ctctttgtcg gaagctgagc aagctgtggc ttttttccaa ctccgtgtga cgtttctgag   1140

tgtagtgtgg taggaccccg gcgggtgtgg cagcaactgc cctggagccc cagcccctgc   1200

gtccatctgt gctgtgcgcc ccacagtaga cgtgcagacg tccctgagag gttcttgaag   1260

atgtttattt atattgtcct tttttactgg aagacgtacg catactccat cgatgttgta   1320

tttgcagtgg ctgaggaatt cttgtacgca gttttctttg gctttacgaa gccgattaaa   1380

agaccgtgtg aaatgaa                                                  1397


<210>  589
<211>  1516
<212>  DNA
<213>  Human

<400>  589
gccctccccg gagcccagag ctcgcagctc cgccggcgcc tggtcccagc gcccgcggcg     60

ccgcgtcccc ggcccaacca tggcgtcctc cgcggccggc tgcgtggtga tcgttggcag    120

tggagtcatt gggcgaagct gggccatgct gtttgccagt ggaggcttcc aggtgaaact    180

ctatgacatt gagcaacagc agataaggaa cgccctggaa aacatcagaa aggagatgaa    240

gttgctggag caggcaggtt ctctgaaagg ctccctgagt gtggaagagc agctgtcact    300

catcagtggt tgtcccaata tccaagaagc agtagagggt gccatgcaca ttcaggaatg    360

tgttccagaa gatctagaac tgaagaagaa gatttttgct cagttagatt ccatcattga    420

tgatcgagtg atcttaagca gttccacttc ttgtctcatg ccttccaagt tgtttgctgg    480

cttggtccat gtgaagcaat gcatcgtggc tcatcctgtg aatccgccat actacatccc    540

gctggttgag ctggtccccc acccggagac ggcccctacg acagtggaca gaacccacgc    600

cctgatgaag aagattggac agtgccccat gcgagtccag aaggaggtgg ccggcttcgt    660

tctgaaccgc ctgcaatatg caatcatcag cgaggcctgg cggctagtgg aggaaggaat    720

cgtgtctcct agtgacctgg accttgtcat gtcagaaggg ttgggcatgc ggtatgcatt    780

cattggaccc ctggaaacca tgcatctcaa tgcagaaggt atgttaagct actgcgacag    840

atacagcgaa ggcataaaac atgtcctaca gacttttgga cccattccag agttttccag    900

ggccactgct gagaaggtta accaggacat gtgcatgaag gtccctgatg acccggagca    960

cttagctgcc aggaggcagt ggagggacga gtgcctcatg agactcgcca agttgaagag   1020

tcaagtgcag ccccagtgaa tttcttgtaa tgcagcttcc actcctctca ttggaggccc   1080

tatttgggaa cactgcaagc ccttaatcag ccctctgtga cataggtagc agcccacgga   1140

gatcctaagc tggctgtctt gtgtgcagcc tgagtggggt ggtgcaggcc ggtagtctgc   1200

ccgtcacttt ggatcatagc cctgggcctg gcggcacagc agcacttgcg ttctcggggc   1260

tgtcgatttc ctgccacctg ggcagataac ctggagattt tcaccttttc ttttcagctt   1320

gattgcattt gactatattt tacagccagt gattgtagtt tcatgttaat atgtggcaaa   1380

atatttttgt aattattttc taatcccttt ctgagtactc tggggccctg catttatgag   1440

gcacctacct tcattttgct aacgcttatt ctgaataaaa gtttttgatt ccttaaagac   1500

aaaaaaaaaa aaaaaa                                                   1516


<210>  590
<211>  3360
<212>  DNA
<213>  Human

<400>  590
atctcgcgag aaagggttgg cggggagggt atccaggacg aggagaggga ggagtcgcca     60

tcgcctccgc ctccgcctcc tcctgttgga ggggggctga gggaggagac tgttgctgat    120

ctttggatgt tctggttagt ctaagaagga gagtatgagg cgagctccgg cccgggtgcg    180

gccgggcttc aggggcccag gcgccgctgc tgccaccgcc atctaacgct gcgccctgga    240

ggcccggcgc gcggatggtg ccggtgcggc tcgggtgttg aaacgggtgt cccctccccc    300

tcctcccctc ccccacgcgg tggtctcccc tcccacccgg ctcaggcaga gccatgtctc    360

ggggtggctc ctacccacac ctgttgtggg acgtgaggaa aaggtccctc gggctggagg    420

acccgtcccg gctgcggagt cgctacctgg gaagaagaga atttatccaa agattaaaac    480

ttgaagcaac ccttaatgtg catgatggtt gtgttaatac aatctgttgg aatgacactg    540

gagaatatat tttatctggc tcagatgaca ccaaattagt aattagtaat ccttacagca    600

gaaaggtttt gacaacaatt cgttcagggc accgagcaaa catatttagt gcaaagttct    660

taccttgtac aaatgataaa cagattgtat cctgctctgg agatggagta atattttata    720

ccaacgttga gcaagatgca gaaaccaaca gacaatgcca atttacgtgt cattatggaa    780

ctacttatga gattatgact gtacccaatg acccttacac ttttctctct tgtggtgaag    840

atggaactgt taggtggttt gatacacgca tcaaaactag ctgcacaaaa gaagattgta    900

aagatgatat tttaattaac tgtcgacgtg ctgccacgtc tgttgctatt tgcccaccaa    960

taccatatta ccttgctgtt ggttgttctg acagctcagt acgaatatat gatcggcgaa   1020

tgctgggcac aagagctaca gggaattatg caggtcgagg gactactgga atggttgccc   1080

gttttattcc ttcccatctt aataataagt cctgcagagt gacatctctg tgttacagtg   1140

aagatggtca agagattctc gttagttact cttcagatta catatatctt tttgacccga   1200

aagatgatac agcacgagaa cttaaaactc cttctgcgga agagagaaga gaagagttgc   1260

gacaaccacc agttaagcgt ttgagacttc gtggtgattg gtcagatact ggacccagag   1320

caaggccgga gagtgaacga gaacgagatg gagagcagag tcccaatgtg tcattgatgc   1380

agagaatgtc tgatatgtta tcaagatggt ttgaagaagc aagtgaggtt gcacaaagca   1440

atagaggacg aggaagatct cgacccagag gtggaacaag tcaatcagat atttcaactc   1500

ttcctacggt cccatcaagt cctgatttgg aagtgagtga aactgcaatg gaagtagata   1560

ctccagctga acaatttctt cagccttcta catcctctac aatgtcagct caggctcatt   1620

cgacatcatc tcccacagaa agccctcatt ctactccttt gctatcttct ccagacagtg   1680

aacaaaggca gtctgttgag gcatctggac accacacaca tcatcagtct gataacaata   1740

atgaaaagct gagccccaaa ccagggacag gtgaaccagt tttaagtttg cactacagca   1800

cagaaggaac aactacaagc acaataaaac tgaactttac agatgaatgg agcagtatag   1860

catcaagttc tagaggaatt gggagccatt gcaaatctga gggtcaggag gaatctttcg   1920

tcccacagag ctcagtgcaa ccaccagaag gagacagtga aacaaaagct cctgaagaat   1980

catcagagga tgtgacaaaa tatcaggaag gagtatctgc agaaaaccca gttgagaacc   2040

atatcaatat aacacaatca gataagttca cagccaagcc attggattcc aactcaggag   2100

aaagaaatga cctcaatctt gatcgctctt gtggggttcc agaagaatct gcttcatctg   2160

aaaaagccaa ggaaccagaa acttcagatc agactagcac tgagagtgct accaatgaaa   2220

ataacaccaa tcctgagcct cagttccaaa cagaagccac tgggccttca gctcatgaag   2280

aaacatccac cagggactct gctcttcagg acacagatga cagtgatgat gacccagtcc   2340

tgatcccagg tgcaaggtat cgagcaggac ctggtgatag acgctctgct gttgcccgta   2400

ttcaggagtt cttcagacgg agaaaagaaa ggaaagaaat ggaagaattg gatactttga   2460

acattagaag gccgctagta aaaatggttt ataaaggcca tcgcaactcc aggacaatga   2520

taaaagaagc caatttctgg ggtgctaact ttgtaatgag tggttctgac tgtggccaca   2580

ttttcatctg ggatcggcac actgctgagc atttgatgct tctggaagct gataatcatg   2640

tggtaaactg cctgcagcca catccgtttg acccaatttt agcctcatct ggcatagatt   2700

atgacataaa gatctggtca ccattagaag agtcaaggat ttttaaccga aaacttgctg   2760

atgaagttat aactcgaaac gaactcatgc tggaagaaac tagaaacacc attacagttc   2820

cagcctcttt catgttgagg atgttggctt cacttaatca tatccgagct gaccggttgg   2880

agggtgacag atcagaaggc tctggtcaag agaatgaaaa tgaggatgag gaataataaa   2940

ctctttttgg caagcactta aatgttctga aatttgtata agacatttat tatatttttt   3000

tctttacaga gctttagtgc aattttaagg ttatggtttt tggagttttt cccttttttt   3060

gggataacct aacattggtt tggaatgatt gtgtgcatga atttgggaga ttgtataaaa   3120

caaaactagc agaatgtttt taaaactttt tgccgtgtat gaggagtgct agaaaatgca   3180

aagtgcaata ttttccctaa ccttcaaatg tgggagcttg gatcaatgtt gaagaataat   3240

tttcatcata gtgaaaatgt tggttcaaat aaatttctac acttgccatt tgcatgtttg   3300

ttgctttcta attaaagaaa ctggttgttt taagataccc tgaaaaaaaa aaaaaaaaaa   3360


<210>  591
<211>  774
<212>  DNA
<213>  Human

<400>  591
ggcctgagtg cgcctgcgca gtccgcgcca ctcagggagc cggaggggac gcgccggagg     60

aaagatggaa gactaccagg ctgcggagga gactgctttt gttgttgatg aagtgagcaa    120

cattgtaaaa gaggctatag aaagcgcaat tggtggtaac gcttatcaac acagcaaagt    180

gaaccagtgg accacaaatg tagtagaaca aactttaagc caactcacca agctgggaaa    240

accatttaaa tacatcgtga cctgtgtaat tatgcagaag aatggagctg gattacacac    300

agcaagttcc tgcttctggg acagctctac tgacgggagc tgcactgtgc gatgggagaa    360

taagaccatg tactgcatcg tcagtgcctt cggactgtct atttgacctg cagtccagcc    420

tatggccttt ctccttttgt ctctagttca tcctctaacc accagccatg aattcagtga    480

actcttttct cattctcttt gttttgtggc actttcacaa tgtagaggaa aaaaccaaat    540

gaccgcactg tgatgtgaat ggcaccgaag tcagatgagt atccctgtag gtcacctgca    600

gcctgcgttg ccacttgtct taactctgaa tatttcattt caaaggtgct aaaatctgaa    660

atctgctagt gtgaaacttg ctctactctc tgaaatgatt caaatacact aattttccat    720

actttatact tttgttagaa taaattattc aaatctaaaa aaaaaaaaaa aaaa          774


<210>  592
<211>  1604
<212>  DNA
<213>  Human

<400>  592
attcgaatcg aacgtcctta cgggagccgg gcgctggcgg agcggcgccc cggccaatca     60

gcggcagtcc ccgaacgttg ggccggccca gccccgcccc gcgctgttgt ttgtggtgtc    120

ggccgggccg cgggagtcga accacaacat tcgccgggcg ggcggcggcg gagcgggcgg    180

cggagcggcg gcagcagcgg tgagcgcgag ccccggagcc ccgggcggcc ggcctcccgc    240

gcccgcgcag ccccgcgtct gcgtccggcc ggagacgccg ggccccgcgc cgcgccgcgc    300

catgtcggtg aacatggacg agctgcggca ccaggtcatg atcaaccagt tcgtgctggc    360

cgcgggctgc gcggccgacc aggcgaagca gttgctgcag gcggcccact ggcagttcga    420

gaccgcgctg agcacgttct tccaagaaac caacattccc aacagccacc accaccacca    480

gatgatgtgc actcccagca acacccctgc cacgccgccc aacttccccg atgcgctggc    540

catgttctcc aagctccgcg cctccgaggg cctgcagagc agcaacagcc ccatgacagc    600

cgcagcctgc tccccacctg caaacttcag ccccttctgg gcctcgtccc cgcccagcca    660

ccaggcgccc tggatcccgc cctcctcccc caccaccttc caccacctcc accgcccaca    720

gcccacgtgg cccccaggag cacagcaggg gggcgcccag cagaaagcca tggcggccat    780

ggacggccag agatgagact ggacgccgcc gggcgctggg ctggagctgg gggcagccca    840

gggttgtggg gacacaggag ggccagggag gggggagccg gggagggcag ggggtttccc    900

gaagatcgca ctggaagatt ttataaaaga atttttgtgg gtcgggggga cagtaaactt    960

cctgggccac gtgggtcctt caggagtttt tcaggcaagt ttttcctctg tttttaatat   1020

ataactataa tatatatgaa tagataaata taactaatgt gcgtgagaat gggcctggca   1080

cacctggggt gctcgggggt agggctgcca tgctgcagag ctgatggagt gatgttgtgg   1140

gcacaaggca tctgtcagct gcctccttta acagccatgc cttctggaat ctggaagagg   1200

acaccactcc tgcagtcact gggcagccac atagcagctg caggtcccag gagggcctga   1260

ggtcaaagct gtggaaggcc ctcttggtat cagggctctc tccccatggc ctcttcccca   1320

cctctgattg ctggttgtgg ccccatagct catcacccct gtctcctgct gaatgtgcag   1380

ggctgatgtg gcactgagga gctgactttg gtcaaaggcc aggctctgcc cagcagggga   1440

cttgactgcc ctgggcgccc tgcccctccc gctgcgtgtc caggtccaaa gtggagagcc   1500

tgcctttggg tttagttccc gaatcagaat cccatctcac cagggcgaaa ttttaattta   1560

aaaacttaaa aagagacttt tctaacttca aaaaaaaaaa aaaa                    1604


<210>  593
<211>  5643
<212>  DNA
<213>  Human

<400>  593
acctccccgc gcgtgcgtgc tgtgccaagg ctgcaaggcg ctgaggggag aggcgccgcc     60

gtcagcgccg ccgcagctgg gacccgttag agcggaagcg ccgccgccac cgccgccttt    120

gctgtccccc ggcctctagt tccccgcagg tgggaggtgg gagccatgtc gaaacggctc    180

cggagcagcg aggtgtgcgc tgactgcagc gggccggatc cttcctgggc atcagtaaat    240

aggggaacgt ttttatgtga tgagtgctgc agtgtccatc ggagtctagg gcgccatatc    300

tcccaagtga ggcatctgaa acacacaccg tggcctccaa cactgcttca gatggttgag    360

accttgtata ataacggtgc taactctata tgggagcatt ctttgctgga ccctgcgtct    420

attatgagtg gaagacgtaa agctaatcca caggataaag tacatcccaa taaagcggaa    480

ttcatcagag ccaagtatca gatgttagcg ttcgtccatc gcttgccctg ccgggatgac    540

gatagtgtga ctgccaaaga tcttagcaag caactccatt cgagcgtgag aacagggaat    600

cttgaaacct gtttgagact gttatcttta ggagcacaag ccaacttctt tcatcctgaa    660

aaaggaaaca ccccactcca tgttgcctcc aaagcagggc agattttaca ggctgaatta    720

ttggcagtat atggagcaga cccaggcaca caggattcta gtgggaaaac tcccgttgat    780

tatgcaaggc aaggagggca ccatgagctg gcagagcgcc tcgtggaaat acagtatgag    840

ctaacggaca gactagcctt ctatctctgt ggcaggaaac cagatcacaa aaatggacag    900

cactttataa tacctcaaat ggcagacagc agcctggatt tgtctgaatt ggcaaaagct    960

gctaagaaga aacttcaatc tctaagtaat catttgtttg aagaacttgc catggatgtg   1020

tacgatgaag ttgacaggcg agagacggat gcagtctggc ttgccacgca aaaccacagc   1080

gccctggtaa ccgagacaac ggtcgtcccc tttcttccgg tcaatcctga gtactcatca   1140

acacgaaatc agggcagaca gaagttagct cggttcaacg cccatgagtt tgccacgctg   1200

gtcattgaca ttctcagtga cgccaagagg agacagcagg gcagttctct ctcgggttca   1260

aaagacaatg tggagctcat actgaaaacc atcaataacc agcacagcgt tgagagtcaa   1320

gacaacgatc agcccgacta tgacagcgtg gcatcagacg aagacacaga tttggaaacc   1380

actgcaagca aaacaaaccg gcagaagagc ctagattcag atttatcaga tggaccagtc   1440

actgtacagg aatttatgga ggtcaaaaac gctctagtgg cttctgaggc caagatacag   1500

cagctaatga aggtgaataa caacttgagt gacgagctga gaattatgca gaaaaagctt   1560

caaacactcc agagtgaaaa ttcgaacctc aggaaacagg ccacaaccaa tgtatatcag   1620

gtgcaaactg gttctgagta cacagacact tccaaccact cttccttaaa gagacgtccg   1680

tctgcccggg gcagtaggcc catgtccatg tacgagaccg gatcaggtca gaaaccatat   1740

ctcccaatgg gagaagcgag ccgccccgaa gagagcagga tgagactcca gcccttcccc   1800

gcgcacatcg ggaggagtgc acttgtgacc tcctcttcat ctctgccttc cttcccctcc   1860

acactttcct ggtcgaggga cgaaagcgcc cgaagggcat ccaggctgga gaagcagaac   1920

agcacacctg agagtgacta cgacaacact cccaacgaca tggagccaga tggcatgggg   1980

tcaagccgaa agggacggca aagaagtatg gtgtggccag gggatggctt ggtaccagac   2040

acagcagaac cccatgtggc cccaagcccc actctcccta gcaccgaaga tgtcatcagg   2100

aagactgaac agatcaccaa aaacatacag gagctcttaa gagcagccca agaaaataaa   2160

catgacagtt atattccctg ctcagagagg atacacgtag ctgttacaga aatggcagca   2220

ttattcccca aaaaacccaa gtctgatatg gtgaggactt cccttcgttt actgacgtcc   2280

agtgcctacc gactgcagtc agagtgcaag aagaccctcc caggggaccc cggctcaccc   2340

acagacgttc agctggtcac gcagcaggtc atccagtgtg cgtacgacat cgccaaggct   2400

gccaagcagc tggttaccat caccaccaaa gagaacaaca actgacaagg gcagggcacc   2460

gcctcctctg ttttctaggc tttataaagt ccaatttcaa attcagacgc agaactcttc   2520

agatttctac aaaaagaaac atttaatgac ggtttaaaac tttttaaaag aaaactcagt   2580

attatttttg catgttttct aaccaatttt caactattta acccacttgc cttattttgt   2640

gcctatttgc tggtttagtt tctgatgttc ggttgtgttg tcaacaactg ttgagttgat   2700

cacatacatc caaaagtata gtttcattgt ctaaagtttg tgaaaacttt tccatccctt   2760

aaaactccct gcctatggct gaaactataa atgaaatttt tcataaaaca ttttcttgag   2820

agagttcagt taaaaaagaa aaaatcagcg tcatttgttc cctgccaagc atcgtgcaat   2880

aagtgaattt cctggcctac ttcataatct ctaagtttgg ggtatctcca agcatgtatg   2940

tagagaaagg actttgccgc tttttaaaac tagtgtcaca gtctctcttg ggaggaaaca   3000

atgaattggt tcatttcttc tcagtgtttt accctgttac atgttctgtt atttaatgtt   3060

gttatctcaa gctcctatct cttgatgttt tcttgtcatc ttgaaggctc catggaatga   3120

gataaagcat tgacccacca caggacatct catgaagcca tgttcagggt aggagctcca   3180

cgcacatcac cacccattgt caggtgctct ccctcacccc tgtaagccag acagtttgtt   3240

caaaacctgc agcaaagaga agcatcagtc taacaagcca gaactcattt tgtgccaccc   3300

atttaggtat cactaccatg aactataggg aaaagaaatc acctactccc tgacactgtg   3360

ttgtaccctt catccaaaag tcagcttgct tctctgacca cttacagctt tctcacatga   3420

gttgcttcac atttttcatc atctttaagg acttcttata aggaaagatg tatcgtatcg   3480

cagtcatctg agttagtttc tcctccatca cctcatgagt acttaaaaat tagacatcaa   3540

ctttcaagag ttccttagag agtgtgctct agctggctgc ctgctacccc aaagctctga   3600

aagagtaagg ttgaagtgct ggaacatgct cagattgttt tttagttact caaaagcccc   3660

ttcttgttct gaatgtgaaa gctcttcccg ttcctgctta ctgcagccat tctgtgtgtg   3720

tggttcagac cctggcctag ggccggtgat gtggatgagt gaagggagcc aggtacacgg   3780

cagcagggca gaggagacta tggggagccc accgcctaca cagtaggggc agtagccccc   3840

agctccacgc ctgttgccat gtggaaaagt gggcctaggg tggccacagc tttgattttt   3900

caagagacaa gaaacctaga tgttttttgg tgccatctct ccatttataa atgttggcaa   3960

ccaatttgaa cactttcaga gaccatgtgc aggtgagctg tgtcctctag gctgccagct   4020

cacagccccc accccagggc cctgtaagct gtgcagtgtg agggcctggc ttccccggac   4080

acacctggag cagcctctga gtcttacccg taatggagcc ggccaaccct gtgtgttatg   4140

ttgctgtcgc tcctgttttt aaccatatgt tctgtcccat agcagtcatt cacacatgtg   4200

aagaagacac aagaatcaaa gtacaagttg cctcaataca tgctaataac taagcttcta   4260

ttttcacagg actgatcgat gcacaccttt atagcttgac catatgctgt catgaaagta   4320

gcaccccgac ggtgcttgct ttactaagtc accgtgtgtg gatgcttttg tcgcattttg   4380

cttcactgtg agtagcatgg gaaaagggtc cacgtctcca aaagactctt ccacttgttt   4440

gtcccacagc cctaagtgcc acattgctgt tggatgctcc cgggatgcct tctagaaggg   4500

ggcctcccac cttaagttca ggcgccatct gatagccttt tctgcaggct tcatgtcctt   4560

agctgaccct cctttatctt gcaaacccct gcccctgctg tcccagggag gacgggcttc   4620

tgtagaggct tctgggaaat gagctgtctg caggaggtga agcagtgttt tccttggaat   4680

gtttgaggac ctgcaataga agatgttgcc tttatggccc tagagaaagt caaggaacat   4740

ggggaccaac aaagcatttc cagttgtaag aatatgtcag aagagtgctc ggttagccca   4800

cggtgccaaa actccaaaca agttccccgg tggaatgacg tggccattgg agggctgcag   4860

gtcgtcctct ctgtatgtgc cccgcgcatt tccttggcct catctgagat ctggtgtcag   4920

agttctctgc tcctgttggc aaatcgcacc ttatctgaac atttgttcca gccacctttt   4980

gcacatggat tccgtacctt gcactagcaa tgtctacctt cagtaacgtc gttctttttc   5040

accctgtatt ctcaatgatc ccttcctccc catatgccac ccttccccca aagctgatag   5100

ggcagaggtg cactttatga aactggcact tgactgaaca gaaggaaaca gctgtacctc   5160

taagctcctt tcacagaaat cgtcatctgc cttggaatgc aaatagttct tatttgccaa   5220

agaacagtga attgggccca aagatcaaac acagcatttc atgtaatcag aattctaaac   5280

gcacaactcg ggagctgtgc acggcttctc aagtgattca gttgcagaac caagagcaaa   5340

actcgcctgt ttttgtcctc aatggcaccc atgagctttc caatagtata gttttctttc   5400

tttccttgtc ctggttgaag gtaacgtgtt cctagaaaag aaaatgctgc ataggaaaac   5460

tgagatgcct tttattccaa cgtgtttgat ccctgtcact cattattctg tactttttat   5520

tgtacattct attcctgtaa ttattgtgcc ctttaagtgt tgtaaaatcg ttttggaatt   5580

tgtgcctgct agttatgcaa taaacaggct ctacaagtgt taaaaaaaaa aaaaaaaaaa   5640

aaa                                                                 5643


<210>  594
<211>  3879
<212>  DNA
<213>  Human

<400>  594
aattgttgag cgggccgtgc tgccaggcac cgcacgttgt gtgtctgccc tactctcgtg     60

gaaccaaggt ccagtggaga gaggaacata agcgaatgaa gaaagaagca atagagtctc    120

agtgataagt tcttggaaaa aaggtctttg ccaatcctga ttcccggaag agagtcggca    180

gaattccttc ctttaggccc ctctggagcc ttggccgacc agccacttct gtggtctggg    240

gacagtcacc gagggtatca aaaagccatt cacagaggtc atccgagcca acatcgggga    300

cgcccaggct atggggcagc agccaatcac cttcctccgg caggtgatgg cactatgcac    360

ctacccaaac ctgctggaca gccccagctt cccagaagat gctaagaaac gtgcccggcg    420

gatcctgcag gcttgtggcg ggaacagcct ggggtcctac agtgctagcc agggtgtcaa    480

ctgcatccgt gaagatgtgg ctgcctacat caccaggagg gatggcggtg tgcctgcgga    540

ccccgacaac atctacctga ccacgggagc tagtgacggc atttctacga tcctgaagat    600

cctcgtctcc gggggcggca agtcacggac aggtgtgatg atccccatcc cacaatatcc    660

cctctattca gctgtcatct ctgagctcga cgccatccag gtgaattact acctggacga    720

ggagaactgc tgggcgctga atgtgaatga gctccggcgg gcggtgcagg aggccaaaga    780

ccactgtgat cctaaggtgc tctgcataat caaccctggg aaccccacag gccaggtaca    840

aagcagaaag tgcatagaag atgtgatcca ctttgcctgg gaagagaagc tctttctcct    900

ggctgatgag gtgtaccagg acaacgtgta ctctccagat tgcagattcc actccttcaa    960

gaaggtgctg tacgagatgg ggcccgagta ctccagcaac gtggagctcg cctccttcca   1020

ctccacctcc aagggctaca tgggcgagtg tggttacaga ggaggctaca tggaggtgat   1080

caacctgcac cctgagatca agggccagct ggtgaagctg ctgtcggtgc gcctgtgccc   1140

cccagtgtct gggcaggccg ccatggacat tgtcgtgaac cccccggtgg caggagagga   1200

gtcctttgag caattcagcc gagagaagga gtcggtcctg ggtaatctgg ccaaaaaagc   1260

aaagctgacg gaagacctgt ttaaccaagt cccaggaatt cactgcaacc ccttgcaggg   1320

ggccatgtac gccttccctc ggatcttcat tcctgccaaa gctgtggagg ctgctcaggc   1380

ccatcaaatg gctccagaca tgttctactg catgaagctc ctggaggaga ctggcatctg   1440

tgtcgtgccc ggcagtggct ttgggcagag ggaaggcact taccacttca ggatgactat   1500

cctccctcca gtggagaagc tgaaaacggt gctgcagaag gtgaaagact tccacatcaa   1560

cttcctggag aagtacgcgt gaggacgcct gagccccagc gggagacctg tccttggctc   1620

ttcctcccaa tgcccgtcag gctgaactcg cctcccccgt gactctgcct cgggcctcgc   1680

agaggccgct ggtcacttcg tcatcatttt gcccctggag acgtctttct ttgtgccttg   1740

atgttgagag cgcctctctt ttgagcaaac aagcattcta tatgcaacca gagtagaggg   1800

gacctgctca gcaggtgtga ccagggttct ctgaatctgt tattgttttt gcttctggaa   1860

agttcatttg gggtttacaa caactaggat gtgttgggtg agatgtttca gatctggaga   1920

aatgagcagg tgtcgggaaa tgtgtgactt aaccgtggtg agggctggaa atccaaactc   1980

accaccatga tctgtgaaat aaagccctta gcggtgtgaa gcatccggtc ctttgaacag   2040

aagggcctgg aaggcccctg gggctgagaa agggtccgcc cggtggcctg gaggcaggcg   2100

ccgggagcgc agtagcacgt ggactgggca ggatgttgca ctagcttggg gtagatgctg   2160

ggggctgcgg ccacggtcag agggccccac tgtgaggcgt gggtgtgagc caggctgcag   2220

gaggaactgg gcctccgctt cccagcaacg cagccaggcc tgagaattct gtgcgcccgg   2280

cgggctttgg gaatgagggg ttcccttgaa catgcgtagg ctggaacccc gtctgagagg   2340

tctccctgaa tttcagtgac acatagtgca gcccggcagt gtcccacttc cgtggagaga   2400

gccgctggaa tggtgtggac ccatcccgcg ggtgaccggt gcctgttctc ccctgaccga   2460

gcctgtgagc acatcgcccc ctgctggcga cagcggggaa atgagggctg aaaatatcct   2520

ccccacaagg gcaatccccg ggacctgccg agcagccaag gccctgtcct ttcttgaatg   2580

gtggcgagct gaatctggtc ggtttcctag cttttaggtg gtaaaagtgc ctggcagctt   2640

ggctgccgtg gaggagtcag tcgtggttgg aggttcattg ccgtgctttc atgcagagtg   2700

ttttgccttc atgttagctt ccggctcccc tcccaggctg cagactctga cctgtggcat   2760

caggcttctc ccagtacagg agggtgccat cccccagcat gcggcttctc tgccattagc   2820

agccctgggc gggccgacca cactcgaggc tgcggtgcta cgggcttagc cctcgcctcc   2880

ctcactggga gcttccccat cctccctgcc ttccccagtg ggaagttagg gaagctcagg   2940

agcctgggac cccgcatgtc ccaaaatggg attggagaag ctggagagaa agcagaagag   3000

gccgaggagt gaggcagcag cctctatgct gtgatttcca caccgggtcc gtgcagagga   3060

aacagaaact cccaactgtc cttacccacc gacatcacag cccctatgaa gaaagtagcc   3120

acaatctcaa ataacaaaag ggaatgttct aaaacttttt cttccttaaa aaatggagaa   3180

aattgcactt gtgcttgctg tgtggtatat aaaccaggat tagtcccagg gtcgtgaggt   3240

ttctggtgaa aaggttaaat cgtagaagct agtatatttt ttatattttt gtaacaattg   3300

cttttttcat gggggaggcg gggttagtat ttatagtcct aacaagtcca gtaatttttt   3360

ataaatcttc agattataaa cagcccctaa aaactttaca acgtttacac agttttttaa   3420

aaagagactg tatacacttg atttgctttc aaaataaata aggtcagcta gtctaggagg   3480

ttaacgtcgg gtaggaatgc tgatcatgat aggtttggtt ttctacagat tctgttccgg   3540

tgcctttcct atccaggcac cacctgagaa agttgtcatt tgaggtcgca cttggaagtt   3600

acatctgtga agtttctgtc attcgtccag atctgtgtgt gtagcatgtg ctgaggaagc   3660

acgtgctggg ctgtgcctca gacagtgcat caccgggcac ccagaggctt gcctggctat   3720

tcctgttctg gtgtgtgtgg agtgttgggg aggaacagat gcagatcaac ctgtggctgt   3780

tttcccgtct aggttctcac aggtatctcc tgacagaggt acttaacaat ggctctgctg   3840

gaaatttcta taaataaaat gtccaaaatg gtgaaaaaa                          3879


<210>  595
<211>  2050
<212>  DNA
<213>  Human

<400>  595
gaaaacctga atacggaact gaagcagcag ctcagtttct cactccgaag tggcagcagc     60

cagagaggga gtcggtgtgg acgcgaggag ccgggcgctt agaacagagg cttgcacagg    120

tggagatgtg gaagtctgta gtgggccatg atgtgtctgt ttccgtggag acccagggtg    180

atgattggga cacagatcct gactttgtga atgacatctc tgaaaaggag caacgatggg    240

gagccaagac catcgagggg tctggacgca cagaacacat caacatccac cagctgagga    300

acaaagtatc agaggagcat gatgttctca ggaagaaaga gatggagtca gggcccaaag    360

catcccatgg ctatggaggt cggtttggag tagaaagaga ccgaatggac aagagtgcag    420

tgggccatga gtatgttgcc gaggtggaga agcactcttc tcagacggat gctgccaaag    480

gctttggggg caagtacgga gttgagaggg acagggcaga caagtcagca gtcggctttg    540

attataaagg agaagtggag aagcacacat ctcagaaaga ttactctcgt ggctttggtg    600

gccggtacgg ggtggagaag gataaatggg acaaagcagc tctgggatat gactacaagg    660

gagagacgga gaaacacgag tcccagagag attatgccaa gggctttggt ggccagtatg    720

gaatccagaa ggaccgagtg gataagagcg ctgtcggctt caatgaaatg gaggccccga    780

ccacagctta taagaagacg acgcccatag aagccgcttc tagtggtacc cgtgggctga    840

aggcgaaatt tgagtccatg gctgaggaga agaggaagcg agaggaagag gagaaggcac    900

agcaggtggc caggaggcaa caggagcgaa aggctgtgac aaagaggagc cctgaggctc    960

cacagccagt gatagctatg gaagagccag cagtaccggc cccactgccc aagaaaatct   1020

cctcagaggc ctggcctcca gttgggactc ctccatcatc agagtctgag cctgtgagaa   1080

ccagcaggga acacccagtg cccttgctgc ccattaggca gactctcccg gaggacaatg   1140

aggagccccc agctctgccc cctaggactc tggaaggcct ccaggtggag gaagagccag   1200

tgtacgaagc agagcctgag cctgagcccg agcctgagcc cgagcctgag aatgactatg   1260

aggacgttga ggagatggac aggcatgagc aggaggatga accagagggg gactatgagg   1320

aggtgctcga gcctgaagat tcttcttttt cttctgctct ggctggatca tcaggctgcc   1380

cggctggggc tggggctggg gctgtggctc tggggatctc agctgtggct ctatatgatt   1440

accaaggaga gggaagtgat gagctttcct ttgatccgga cgacgtaatc actgacattg   1500

agatggtgga cgagggctgg tggcggggac gttgccatgg ccactttgga ctcttccctg   1560

caaattatgt caagcttctg gagtgactag agctcactgt ctactgcaac tgtgatttcc   1620

catgtccaaa gtggctctgc ctccaccccc tccctattcc tgctgcaaat gtctaaccag   1680

atgaggttct ggacagactt ccctctcctg cttcattaag ggcttggggc agagacagca   1740

tggggaagga ggtccccttc cccaagagtc ctctctatcc tggatgagct catgaacatt   1800

tctcttgtgt tcctgactcc ttcccaatga acacctctct gccaccccaa gctctgctct   1860

cctcctctgt gagctctggg cttcccagtt tgtttacccg ggaaagtacg tctagattgt   1920

gtggtttgcc tcattgtgct atttgcccac tttccttccc tgaagaaata tctgaacctt   1980

ctttctgttc agtcctaaaa ttcgaaataa agtgagacta tggttcacct gtaaaaaaaa   2040

aaaaaaaaaa                                                          2050


<210>  596
<211>  2339
<212>  DNA
<213>  Human

<400>  596
acgcggtgcc gcggggcggg agtagaggcg gagggagggg acacgggctc attgcggtgt     60

gcgccctgca ctctgtccct cactcgccgc cgacgacctg tctcgccgag cgcacgcctt    120

gccgccgccc cgcagaaatg cttcggttac ccacagtctt tcgccagatg agaccggtgt    180

ccagggtact ggctcctcat ctcactcggg cttatgccaa agatgtaaaa tttggtgcag    240

atgcccgagc cttaatgctt caaggtgtag accttttagc cgatgctgtg gccgttacaa    300

tggggccaaa gggaagaaca gtgattattg agcagagttg gggaagtccc aaagtaacaa    360

aagatggtgt gactgttgca aagtcaattg acttaaaaga taaatacaaa aacattggag    420

ctaaacttgt tcaagatgtt gccaataaca caaatgaaga agctggggat ggcactacca    480

ctgctactgt actggcacgc tctatagcca aggaaggctt cgagaagatt agcaaaggtg    540

ctaatccagt ggaaatcagg agaggtgtga tgttagctgt tgatgctgta attgctgaac    600

ttaaaaagca gtctaaacct gtgaccaccc ctgaagaaat tgcacaggtt gctacgattt    660

ctgcaaacgg agacaaagaa attggcaata tcatctctga tgcaatgaaa aaagttggaa    720

gaaagggtgt catcacagta aaggatggaa aaacactgaa tgatgaatta gaaattattg    780

aaggcatgaa gtttgatcga ggctatattt ctccatactt tattaataca tcaaaaggtc    840

agaaatgtga attccaggat gcctatgttc tgttgagtga aaagaaaatt tctagtatcc    900

agtccattgt acctgctctt gaaattgcca atgctcaccg taagcctttg gtcataatcg    960

ctgaagatgt tgatggagaa gctctaagta cactcgtctt gaataggcta aaggttggtc   1020

ttcaggttgt ggcagtcaag gctccagggt ttggtgacaa tagaaagaac cagcttaaag   1080

atatggctat tgctactggt ggtgcagtgt ttggagaaga gggattgacc ctgaatcttg   1140

aagacgttca gcctcatgac ttaggaaaag ttggagaggt cattgtgacc aaagacgatg   1200

ccatgctctt aaaaggaaaa ggtgacaagg ctcaaattga aaaacgtatt caagaaatca   1260

ttgagcagtt agatgtcaca actagtgaat atgaaaagga aaaactgaat gaacggcttg   1320

caaaactttc agatggagtg gctgtgctga aggttggtgg gacaagtgat gttgaagtga   1380

atgaaaagaa agacagagtt acagatgccc ttaatgctac aagagctgct gttgaagaag   1440

gcattgtttt gggagggggt tgtgccctcc ttcgatgcat tccagccttg gactcattga   1500

ctccagctaa tgaagatcaa aaaattggta tagaaattat taaaagaaca ctcaaaattc   1560

cagcaatgac cattgctaag aatgcaggtg ttgaaggatc tttgatagtt gagaaaatta   1620

tgcaaagttc ctcagaagtt ggttatgatg ctatggctgg agattttgtg aatatggtgg   1680

aaaaaggaat cattgaccca acaaaggttg tgagaactgc tttattggat gctgctggtg   1740

tggcctctct gttaactaca gcagaagttg tagtcacaga aattcctaaa gaagagaagg   1800

accctggaat gggtgcaatg ggtggaatgg gaggtggtat gggaggtggc atgttctaac   1860

tcctagacta gtgctttacc tttattaatg aactgtgaca ggaagcccaa ggcagtgttc   1920

ctcaccaata acttcagaga agtcagttgg agaaaatgaa gaaaaaggct ggctgaaaat   1980

cactataacc atcagttact ggtttcagtt gacaaaatat ataatggttt actgctgtca   2040

ttgtccatgc ctacagataa tttattttgt atttttgaat aaaaaacatt tgtacattcc   2100

tgatactggg tacaagagcc atgtaccagt gtactgcttt caacttaaat cactgaggca   2160

tttttactac tattctgtta aaatcaggat tttagtgctt gccaccacca gatgagaagt   2220

taagcagcct ttctgtggag agtgagaata attgtgtaca aagtagagaa gtatccaatt   2280

atgtgacaac ctttgtgtaa taaaaatttg tttaaagtta aaaaaaaaaa aaaaaaaaa    2339


<210>  597
<211>  1137
<212>  DNA
<213>  Human

<400>  597
actcgcgccc ttgccgctgc caccgcaccc cgccatggag cggccgtcgc tgcgcgccct     60

gctcctcggc gccgctgggc tgctgctcct gctcctgccc ctctcctctt cctcctcttc    120

ggacacctgc ggcccctgcg agccggcctc ctgcccgccc ctgcccccgc tgggctgcct    180

gctgggcgag acccgcgacg cgtgcggctg ctgccctatg tgcgcccgcg gcgagggcga    240

gccgtgcggg ggtggcggcg ccggcagggg gtactgcgcg ccgggcatgg agtgcgtgaa    300

gagccgcaag aggcggaagg gtaaagccgg ggcagcagcc ggcggtccgg gtgtaagcgg    360

cgtgtgcgtg tgcaagagcc gctacccggt gtgcggcagc gacggcacca cctacccgag    420

cggctgccag ctgcgcgccg ccagccagag ggccgagagc cgcggggaga aggccatcac    480

ccaggtcagc aagggcacct gcgagcaagg tccttccata gtgacgcccc ccaaggacat    540

ctggaatgtc actggtgccc aggtgtactt gagctgtgag gtcatcggaa tcccgacacc    600

tgtcctcatc tggaacaagg taaaaagggg tcactatgga gttcaaagga cagaactcct    660

gcctggtgac cgggacaacc tggccattca gacccggggt ggcccagaaa agcatgaagt    720

aactggctgg gtgctggtat ctcctctaag taaggaagat gctggagaat atgagtgcca    780

tgcatccaat tcccaaggac aggcttcagc atcagcaaaa attacagtgg ttgatgcctt    840

acatgaaata ccagtgaaaa aaggtgaagg tgccgagcta taaacctcca gaatattatt    900

agtctgcatg gttaaaagta gtcatggata actacattac ctgttcttgc ctaataagtt    960

tcttttaatc caatccacta acactttagt tatattcact ggttttacac agagaaatac   1020

aaaataaaga tcacacatca agactatcta caaaaattta ttatatattt acagaagaaa   1080

agcatgcata tcattaaaca aataaaatac tttttatcac aacacagtaa aaaaaaa      1137


<210>  598
<211>  7391
<212>  DNA
<213>  Human

<400>  598
atgacctcac ggacaaagcg aaggcagaaa gttaaaatca gcatatcgaa aataaatcac     60

tctagttacc gaaaagaaca taggccgttt tgggagcacc agccacctcc acaccagaac    120

tgggctgtcg ggggccgctg cggcgcaggg gctcgtccgg gactgagtca gcgccggggc    180

cgagaagttc ggcgggaggc gcagggcggg gcttcctccc gccgactccg agcccggctc    240

tacttttctg agtccacgtc tcttcctttg gacaggcgtg gcagcccggg cccgctcggc    300

ccagcccctc acggactgcg gcgcgcggct ccccggggcc cggcccgccg aacgcctcgc    360

tctacagccc tcacctcgcg gcgccgagcg cagcgtccgc ggcatggaga ccggctccga    420

ctcaggtcag aggcccgccc ccgggccgcg ggggactggc cctgcgcgcg cggcggcgcg    480

gttaggccgg gccgcccgca caggccgccg cgtgtcgagt ccgcgcgggg agcgcacgcg    540

gggcgggcgg cgacagatca gcttgaacgg gtctttttac gacttggcca tgctgaaaca    600

gatgaacaat tacagaatat tatatctaaa ttccttcctc ctgttttgct caaactctct    660

agcacccaag aaggagtacg taaaaaggta atggaactgc tggtccatct gaataaacgt    720

ataaaaagcc gccccaaaat acaacttcca gtagagacac tgttggttca gtaccaggac    780

cctgctgcag tttcctttgt cacaaatttt actataattt atgttaaaat gggctatcct    840

cgcctaccag tggaaaaaca atgtgaactg gcccctacgc ttcttactgc catggaaggg    900

aagcctcagc cacagcagga tagcttaatg catcttttaa taccaaccct ttttcacatg    960

aaataccctg ttgaatcatc aaaatcagct tctccattta atcttgctga gaaaccaaag   1020

actgtgcagc tgcttttgga cttcatgcta gatgtccttc tgatgcctta tggttacgtg   1080

ttaaatgaat cccagagtcg ccaaaattca tcttcagcac agggttcttc ttcaaacagt   1140

ggcggaggtt ctggaatccc acagcctcct ccgggaatga gcttttatgc agccaaacga   1200

gttattggtg ataacccatg gacacctgaa caattggaac agtgcaaatt gggaatcgtg   1260

aaattcatag aagctgaaca ggtgcctgaa cttgaagctg ttctccactt ggtgattgcc   1320

tctagtgata cacgccacag tgtggcaacg gcagcagacc tggaattgaa aagcaaacag   1380

agcttaattg actggaataa tcctgccatc attaataaga tgtacaaggt gtaccttgga   1440

gatataccac tgaagacaaa agagggtgca gttctgaagc cagagttgaa aagggaccct   1500

gtcagtacaa gagtcaagtt aaagattgtc ccccatctcc tccgctctag acaagctgct   1560

gaaacgttcc cagccaacat tcaggtggtg tatgatggac tttttggtac aaatacaaat   1620

tcaaagttaa gaacattatc cctgcaattt gtgcatcata tttgtataac ctgtccagaa   1680

atcaagatta agccattagg tccaatgctt ttgaatggcc tcaccaagct aatcaatgaa   1740

tacaaagagg accctaaact actgtcaatg gcatattcag ctgttggaaa actctccagt   1800

cggatgccac atttattcac taaggatata gcgcttgtgc agcagctttt tgaagccctt   1860

tgcaaggaag agcctgagac tcgacttgct attcaagaag ctttatctat gatggttgga   1920

gcgtatagta ctttggaagg ggcacagcga actctcatgg aggcacttgt ggcttcgtac   1980

ttaataaagc ctgaagttca agttcgacaa gtggctgtga aatttgccag tacggtgttt   2040

ccctcagatc atatcccttc cagatatttg ctgctactgg ctgcaggaga tccacgtgaa   2100

gaagttcatg gagaagcaca acgcgtatta aggtgtcttc caggtagaaa cagaaaagaa   2160

agtacttctg agcagatgcc ttccttccca gaaatggttt attacatcca agaaaaggct   2220

tctcatcgaa tgaaaactcc agtcaagtac atgaccggga ccactgtcct tccatttaac   2280

ccagcagcct ttggagagat cgttctgtac ttgcgcatgt gccttgcgca cagtgcgggg   2340

gtggtgccca cctctcagag tttggctgat atgcaggatc atgccccagc cattgggcgc   2400

tacatacgga ctttaatgtc aagcgggcag atggcaccct catcatctaa caagagtggg   2460

gagactaacc ctgtccagat ctacattggc ctgcttcagc agctgttagc aggtgttgga   2520

ggtttgccgg ttatgtactg tctattggaa gctgtgtcag tgtatccaga aaagctggct   2580

accaaatttg tagacaaaac agaatggata aagagtctga tgaataacag taaagaagaa   2640

atgcgcgaac tggcagcgtt gttttattct gtagtggtat caacagtgtc ggggaatgag   2700

ttgaaatcaa tgatagaaca gcttataaag actacaaaag acaatcacag cccggagata   2760

cagcatggat ccttgcttgc attgggattc acggtgggaa ggtatttggc taaaaagaaa   2820

atgagaatgt cagagcaaca agacctggag agaaatgctg acaccctccc tgatcaagag   2880

gaactcattc agagtgctac agaaacaata ggctcatttt tggacagtac atcacccctc   2940

ctggcaattg ctgcctgcac agccctgggt gaaattggca gaaatggtcc acttccaatc   3000

cccagtgagg gatctggctt taccaaattg catcttgtag aaagcttact aagtagaata   3060

ccttccagta aagaaacaaa taagatgaaa gaacgagcaa tccaaacact gggatatttt   3120

ccagttgggg atggagattt tcctcaccag aaactcctct tgcaaggtct gatggattct   3180

gtggaggcca agcagataga acttcagttc actattggcg aagccattac cagtgctgca   3240

ataggaacta gttctgtggc tgcccgagat gcctggcaaa tgactgaaga ggaatatact   3300

ccacctgctg gagccaaagt gaatgatgtg gttccatggg tgttggatgt gattttaaat   3360

aaacatatca tcagccccaa cccacacgtg aggcaagcag cctgcatctg gctcctttcc   3420

cttgtcagga agctaagtac ccacaaagaa gtgaagtctc atcttaaaga aattcaaagt   3480

gcatttgttt cagttctatc agaaaatgat gaacttagcc aagatgttgc atcaaagggc   3540

cttgggttgg tttatgaact aggcaatgaa caagatcaac aggaattggt ttctacactt   3600

gtggaaacac ttatgactgg caaaagagtt aaacatgaag tttctggaga gacagtggta   3660

tttcaagggg gagctcttgg caaaacacca gatggtcagg gcctttctac ttacaaggaa   3720

ctttgttctc tggcaagtga tcttagccag ccagatctgg tgtataaatt tatgaattta   3780

gccaaccatc atgcaatgtg gaactctagg aagggtgctg cttttggttt taatgtaatt   3840

gctaccagag ctggagagca gctggctcct tttctgcctc agctagttcc tcgactttat   3900

cgttaccagt ttgatcccaa ccttggcatt cgacaggcca tgacaagtat ttggaatgcg   3960

ttggtcactg acaaatccat ggtggataaa tatttgaaag aaattcttca agatttggtt   4020

aagaacctta caagcaatat gtggcgagtt cgagaatcca gctgtttagc tttgaatgat   4080

ttattgagag gaagaccctt agatgacatc attgataaac ttccagaaat ttgggaaacg   4140

ctttttagag tacaagatga tatcaaggaa tctgtacgaa aagcggcaga actagctctg   4200

aaaactctga gcaaggtctg tgtgaaaatg tgtgaccctg ccaaaggagc agctggccag   4260

agaaccatcg ctgcccttct gccttgcctt ctggacaaag gaatgatgag caccgtgacg   4320

gaagttcgag ccctcagcat taacaccctt gtgaagatca gcaaaagtgc aggagccatg   4380

ttgaaaccgc atgcaccaaa actcattcca gctctgctag agtccttaag tgtattggag   4440

ccccaagttc tcaattattt gagcctccgg gcgacagagc aagaaaaggc tgcgatggat   4500

agtgctcggc ttagtgctgc caaatcttct ccaatgatgg aaacaatcaa catgtgcctg   4560

caataccttg atgtgtcagt gctgggcgag ctagttccta ggttgtgtga actgatcaga   4620

agtggtgtag gtcttggaac taagggtggc tgtgccagtg tcattgtgtc attaactact   4680

cagtgtcctc aggacctaac accttactca ggtaaactta tgagtgcttt gctgagtggc   4740

ctgacagatc ggaacagtgt gattcagaaa tcttgtgcat ttgctatggg ccatttagtt   4800

cggacctcac gggatagcag cactgaaaaa ctcctgcaga agctcaatgg gtggtatatg   4860

gagaaagaag aacctatcta caagacctct tgtgctttga ctattcatgc tattggacga   4920

tacagccctg atgtattaaa gaatcatgca aaagaagtcc tgcctctggc atttttaggc   4980

atgcatgaaa ttgctgatga ggagaaatcc gaaaaagaag aatgtaattt atggaccgaa   5040

gtgtggcagg aaaacgtacc tggatccttt ggtggcattc gattatacct gcaggagtta   5100

attactatta cccagaaggc tttgcagtct cagtcctgga aaatgaaagc ccagggtgca   5160

attgccatgg catcaattgc aaaacagact agctctctag tacctccata tctcggaatg   5220

atactgaccg cattgctgca aggcctggct ggaagaacgt gggcaggaaa ggaggagcta   5280

ttgaaagcca ttgcctgtgt ggtgacagct tgcagtgcag agctggaaaa gtctgtgccc   5340

aatcaaccca gcacaaatga aattcttcaa gctgttctga aggaatgtag caaagagaat   5400

gtcaaataca agattgtagc aatcagctgt gcagctgata tcttgaaggc caccaaagag   5460

gacagattcc aggagttctc taacattgtc atacctctca tcaagaagaa ctcacttgaa   5520

agcagtgggg tccggacaac caaaaatgaa gaggagaatg aaaaggaaaa ggagctccag   5580

ctggaatatc tgctgggtgc ctttgaaagc ctgggcaaag cctggccgcg aaacgcggag   5640

acccaacgtt gttatcgtca ggagctgtgc aaactgatgt gtgaacggct aaaactcagc   5700

acgtggaaag tgcagctagg agtcctgcaa tcaatgaatg ccttttttca ggggttaatg   5760

cttttggaag aagaacatgc cgatcctgag gctttggctg aaattctgct tgaaacttgt   5820

aaatcaatca catattcttt agaaaataag acctactcat ctgtgagaac agaagcttta   5880

tctgtgatag aattgctgct taaaaaactt gaagaatcta aacagtggga atgtttgaca   5940

tctgaatgca gagtgctcct aattgagtct ttagctacta tggagccaga cagcagacct   6000

gaactgcagg agaaagcagc gttactgaag aaaacacttg aaaatctgga ataaattaga   6060

aggggaagaa acaaacaagt gccatgttca ttgggggttg aagtggtggt gttctttgaa   6120

aaaccaagtg ggaaaaagta aagattaatc tgtagcatgc atcattcctt ggctgaaata   6180

aaaagaaaaa gccttaaatt ttgttcctta ttagctttat tttactttat gtttttaaag   6240

tatctgggct gagtgagctt aatggaacct tggatgtttg aggggtggtt gtaaaggaaa   6300

ctggcagaaa tagttactaa aagagttcaa gctgttatta aaggaattaa tagacagagt   6360

tgcagagcaa gctggataaa aatcttagaa ctgcattcaa attagttatt tcaggaaggg   6420

gccctataaa taacttattt taacctccct cttacacctg aagaaatagg aagctgtgtc   6480

atctcagagg ctttctgagg cctgtgccaa agtcagaacc caggtgttta atgtctggcc   6540

ctggatactt tcttttatgg ccatctgcca aatcagtgct aaccccggct tacccaagaa   6600

acttccaaga tgaggtacgt ttagggtggc acacagcagt ctttgtgcca gaactaaact   6660

gacccttacc attgggtttc tgaaagccag aagctaaaca ttgtcttgtc atgtgtttag   6720

gtggttgatt tggagaaaat gattgtttag catctttaca gatggagagg acagagtcag   6780

tctccttcgg ataattccaa tcgtcttcct tttacaggtg gataaagtag attaggacaa   6840

gatcacacat tctatctgtg tctgtggctg catattttgc aaaaccagaa acaaaatcgc   6900

agactgccgt ggtttagacc atttataatg tcaaaactgt aatgacaaat ttctgttcac   6960

ttttatgcta ccagtatgac tttatagggg agaaggaaag ccttttaatt agccacctgg   7020

gaattactct tttaaaaaat gccttttctc aaaagaacat gataccactc caagtaaatc   7080

attgccacta ggggttttcc tccttccttc tgttgcccat gcccctgcct gaaagtgtag   7140

ggtaagagga aaaacaagta aaaccttagt gttgatggta aactgagaac tctgtagctt   7200

accttggatt ccagagcaga agactggttt acattcagta ctcatcctta ttgacgttaa   7260

caccaggaat ctccatgttt attatttttc gtggaaactc catgtttatt atttttggtg   7320

gtctctattg accaatgtat ttcaaacttt tttgactgca agtcataata aaaataactt   7380

tttacatcac g                                                        7391


<210>  599
<211>  3121
<212>  DNA
<213>  Human

<400>  599
taggactgat ctccaggacc agcactcttc tcccagccct tagggtcctg ctcggccaag     60

gccttccctg ccatgcgacc tgtcagtgtc tggcagtgga gcccctgggg gctgctgctg    120

tgcctgctgt gcagttcgtg cttggggtct ccgtcccctt ccacgggccc tgagaagaag    180

gccgggagcc aggggcttcg gttccggctg gctggcttcc ccaggaagcc ctacgagggc    240

cgcgtggaga tacagcgagc tggtgaatgg ggcaccatct gcgatgatga cttcacgctg    300

caggctgccc acatcctctg ccgggagctg ggcttcacag aggccacagg ctggacccac    360

agtgccaaat atggccctgg aacaggccgc atctggctgg acaacttgag ctgcagtggg    420

accgagcaga gtgtgactga atgtgcctcc cggggctggg ggaacagtga ctgtacgcac    480

gatgaggatg ctggggtcat ctgcaaagac cagcgcctcc ctggcttctc ggactccaat    540

gtcattgagg tagagcatca cctgcaagtg gaggaggtgc gaattcgacc cgccgttggg    600

tggggcagac gacccctgcc cgtgacggag gggctggtgg aagtcaggct tcctgacggc    660

tggtcgcaag tgtgcgacaa aggctggagc gcccacaaca gccacgtggt ctgcgggatg    720

ctgggcttcc ccagcgaaaa gagggtcaac gcggccttct acaggctgct agcccaacgg    780

cagcaacact cctttggtct gcatggggtg gcgtgcgtgg gcacggaggc ccacctctcc    840

ctctgttccc tggagttcta tcgtgccaat gacaccgcca ggtgccctgg ggggggccct    900

gcagtggtga gctgtgtgcc aggccctgtc tacgcggcat ccagtggcca gaagaagcaa    960

caacagtcga agcctcaggg ggaggcccgt gtccgtctaa agggcggcgc ccaccctgga   1020

gagggccggg tagaagtcct gaaggccagc acatggggca cagtctgtga ccgcaagtgg   1080

gacctgcatg cagccagcgt ggtgtgtcgg gagctgggct tcgggagtgc tcgagaagct   1140

ctgagtggcg ctcgcatggg gcagggcatg ggtgctatcc acctgagtga agttcgctgc   1200

tctggacagg agctctccct ctggaagtgc ccccacaaga acatcacagc tgaggattgt   1260

tcacatagcc aggatgccgg ggtccggtgc aacctacctt acactggggc agagaccagg   1320

atccgactca gtgggggccg cagccaacat gaggggcgag tcgaggtgca aataggggga   1380

cctgggcccc ttcgctgggg cctcatctgt ggggatgact gggggaccct ggaggccatg   1440

gtggcctgta ggcaactggg tctgggctac gccaaccacg gcctgcagga gacctggtac   1500

tgggactctg ggaatataac agaggtggtg atgagtggag tgcgctgcac agggactgag   1560

ctgtccctgg atcagtgtgc ccatcatggc acccacatca cctgcaagag gacagggacc   1620

cgcttcactg ctggagtcat ctgttctgag actgcatcag atctgttgct gcactcagca   1680

ctggtgcagg agaccgccta catcgaagac cggcccctgc atatgttgta ctgtgctgcg   1740

gaagagaact gcctggccag ctcagcccgc tcagccaact ggccctatgg tcaccggcgt   1800

ctgctccgat tctcctccca gatccacaac ctgggacgag ctgacttcag gcccaaggct   1860

gggcgccact cctgggtgtg gcacgagtgc catgggcatt accacagcat ggacatcttc   1920

actcactatg atatcctcac cccaaatggc accaaggtgg ctgagggcca caaagctagt   1980

ttctgtctcg aagacactga gtgtcaggag gatgtctcca agcggtatga gtgtgccaac   2040

tttggagagc aaggcatcac tgtgggttgc tgggatctct accggcatga cattgactgt   2100

cagtggattg acatcacgga tgtgaagcca ggaaactaca ttctccaggt tgtcatcaac   2160

ccaaactttg aagtagcaga gagtgacttt accaacaatg caatgaaatg taactgcaaa   2220

tatgatggac atagaatctg ggtgcacaac tgccacattg gtgatgcctt cagtgaagag   2280

gccaacagga ggtttgaacg ctaccctggc cagaccagca accagattat ctaagtgcca   2340

ctgccctctg caaaccacca ctggccccta atggcagggg tctgaggctg ccattacctc   2400

aggagcttac caagaaaccc atgtcagcaa ccgcactcat cagaccatgc actatggatg   2460

tggaactgtc aagcagaagt tttcaccctc cttcagaggc cagctgtcag tatctgtagc   2520

caagcatggg aatctttgct cccaggccca gcaccgagca gaacagacca gagcccacca   2580

caccacaaag agcagcacct gactaactgc ccacaaaaga tggcagcagc tcattttctt   2640

taataggagg tcaggatggt cagctccagt atctccccta agtttagggg gatacagctt   2700

tacctctagc cttttggtgg gggaaaagat ccagccctcc cacctcattt tttactataa   2760

tatgttgcta ggtataattt tattttatat aaaaagtgtt tctgtgattc ttcagagccc   2820

aggagtcagt gctggtggtt ggagggacct gcccccactg gttcatttaa ccctctgtct   2880

cggtgccctc agaacctcag ccagaaaggc aaggaggaaa tcagagcagg agcctcatac   2940

tcttggtgat ctattcattc tgtgacctca ggggtcacat ataaggtcag tgtttctcgt   3000

ccccgccgga tctgcactgc caactgggat tgggttcgaa cagcttcata aacatcttca   3060

gcattttgta ccatctgctc cccaatggcc aaaatcacat caccaggccg cagaccagcc   3120

c                                                                   3121


<210>  600
<211>  9445
<212>  DNA
<213>  Human

<400>  600
gggataatgc tcccggagaa ggattctgca gcagttctca aaggctagac ttgagtggta     60

ttgctgcata tgcgctgatt cttcagcttg tctctaaccg aggaagcatt gattgggagc    120

tactcattca gaaaattaaa agaaagaagc cagaaaatat tatcaaccct ttgagaacac    180

gacacaacga actttatatt ttaccacttc cttgaatagt tgcaggagaa ataacaaggc    240

attgaagaat ggcagatgaa cggaaagatg aagcaaaggc acctcactgg acctcagcac    300

cgctaacaga ggcatctgca cactcacatc cacctgagat taaggatcaa ggcggagcag    360

gggaaggact tgtccgaagc gccaatggat tcccatacag ggaggatgaa gagggtgcct    420

ttggagagca tgggtcacag ggcacctatt caaataccaa agagaatggg atcaacggag    480

agctgacctc agctgacaga gaaacagcag aggaggtgtc tgcaaggata gttcaagtag    540

tcactgctga ggctgtagca gtcctgaaag gtgaacaaga gaaagaagct caacataaag    600

accagactgc agctctgcct ttagcagctg aagaaacagc taatctgcct ccttctccac    660

ccccatcacc tgcctcagaa cagactgtca cagtggagga agatttactt acagcctcga    720

agatggagtt ccacgatcaa caggaattga ctccctctac agctgagcct tcagaccaga    780

aggaaaagga gtcagagaag caaagtaagc ctggtgaaga ccttaaacat gctgccttag    840

tttctcagcc agagacaact aaaacttacc ctgataaaaa ggacatgcaa ggcacggaag    900

aagaaaaagc acccctagct ttgtttgggc acactcttgt tgccagcctg gaagacatga    960

aacagaagac agaaccaagc cttgtagtac ctggcattga cctccctaaa gagcctccaa   1020

ctccaaaaga acaaaaggac tggttcatcg aaatgccaac ggaagcaaaa aaggatgagt   1080

ggggtttagt tgcccccata tctcctggcc ctctgactcc catgagggaa aaagatgtat   1140

ttgatgatat cccaaaatgg gaagggaaac agtttgattc tcccatgcca agtccctttc   1200

aagggggaag cttcactctt cctttagatg tcatgaagaa tgaaatagtt acagaaacat   1260

cgccctttgc ccctgccttt ttacagccag atgacaaaaa atctctgcaa caaaccagtg   1320

gcccagctac tgccaaagat agttttaaaa ttgaagagcc ccatgaggct aaacctgaca   1380

aaatggcaga agcaccaccc tcagaggcaa tgaccttacc caaagatgct cacattccag   1440

ttgtagaaga acatgttatg gggaaagttt tagaggaaga aaaggaggcc ataaatcaag   1500

agactgtgca gcaaagggat actttcaccc ccagtggaca ggaacctata cttactgaaa   1560

aggaaactga gctgaagctt gaagaaaaaa ccaccatttc tgacaaagaa gctgtgccaa   1620

aagagagtaa acccccaaaa cctgcagatg aagaaatagg cataattcag acctccacag   1680

agcacacttt ctcagaacag aaagaccaag agcctaccac agatatgttg aaacaggact   1740

cgttccctgt aagtttggag caagcagtta cagattcagc catgacctct aaaacactgg   1800

agaaagccat gaccgaacca tctgcattaa ttgaaaagag ctcaattcag gaactttttg   1860

aaatgagagt tgatgacaaa gataagattg aaggagttgg agctgcaaca tcagctgagc   1920

ttgatatgcc attttatgaa gataaatcag gaatgtccaa gtactttgaa acatctgcct   1980

tgaaagaaga agcaacaaaa agcattgagc caggcagtga ttactatgaa ctgagtgaca   2040

ctagagaaag tgtccatgag tctattgata ccatgtctcc catgcataaa aatggtgaca   2100

aggagtttca aacaggaaaa gaatcccagc ccagtcctcc agcacaagaa gcagggtaca   2160

gcactctcgc acagagttat ccatcagatt tacctgaaga acccagttct cctcaagaaa   2220

gaatgttcac tattgatcca aaagtgtatg gagagaaaag ggacctccac agtaagaata   2280

aggatgattt gacccttagc aggagtttag gacttggtgg taggtctgca atagaacaaa   2340

gaagcatgtc aatcaatttg ccgatgtctt gcctagattc catagccctt ggatttaact   2400

ttggtcgggg acatgatctt tctcctctgg cttccgatat tctaaccaac actagtggaa   2460

gtatggatga aggggatgat taccttccag ccaccacacc tgcactggag aaagcccctt   2520

gcttccctgt agaaagcaaa gaggaagaac agatagagaa agtaaaagct actggagaag   2580

aaagtactca agcggagata tcatgtgagt ctcctttcct agccaaagat ttttacaaaa   2640

atggtactgt catggcacct gaccttcctg aaatgctaga tctggcaggc acaaggtcaa   2700

gattggcttc tgtgagtgca gatgctgagg ttgccaggag gaaatcagtc ccatcagaga   2760

ctgtggttga ggatagtcgt actggcttgc ccccggtaac tgatgaaaac catgtcattg   2820

taaaaacgga cagtcagctc gaagacctgg gctactgtgt gttcaataag tacacagtcc   2880

cattgccatc acctgttcaa gacagtgaga atttatcagg ggagagtggt accttttacg   2940

aaggcactga tgataaagtt cgaagagatt tggccacaga cctttcactg attgaagtga   3000

aactggcagc agccggaaga gtcaaagatg agttcagtgt tgacaaagaa gcatccgcgc   3060

atatctctgg tgacaaatca ggactgagta aggagtttga ccaagagaag aaagctaatg   3120

ataggttgga tactgtacta gaaaagagtg aagaacatgc tgattcaaaa gaacatgcca   3180

agaaaactga agaggctggt gatgaaatag aaacattcgg attaggagta acctatgagc   3240

aagctttggc caaagatttg tcaataccaa cagatgcatc ctctgagaaa gcagagaagg   3300

gtcttagttc agtgccagag atagctgagg tagaaccatc caaaaaggtg gaacaaggtc   3360

tggattttgc tgtccagggt caactagatg ttaaaattag tgactttgga cagatggctt   3420

cagggctaaa catagatgat agaagggcaa cagagctaaa acttgaggct acacaggaca   3480

tgaccccctc atccaaagca ccgcaggagg cagatgcatt tatgggtgtt gagtctggcc   3540

acatgaaaga aggcactaaa gttagtgaga cagaagtcaa agagaaggtg gccaagcctg   3600

acttggtgca ccaggaggct gtagacaagg aggagtccta tgaatctagt ggtgagcatg   3660

aaagtctcac catggagtcc ttgaaagctg atgagggcaa gaaggaaaca tctccagaat   3720

catctctaat tcaagatgag attgccgtca aattgtcagt ggaaatacct tgcccacctg   3780

ctgtttcaga ggctgattta gccacagatg agagagctga tgtccagatg gaatttattc   3840

aggggccaaa agaagaaagc aaagagaccc cagatatatc catcacgcct tctgatgttg   3900

cagagccatt gcatgaaacg atcgtatctg aaccagcaga gattcagagt gaggaagaag   3960

agatagaagc ccagggagaa tatgataaac tgctcttccg ctcagacacc cttcagataa   4020

ctgacctggg tgtctcaggt gccagggagg aatttgtgga gacctgccca agtgaacaca   4080

aaggagtgat tgagtctgtt gtgaccatcg aggatgattt catcactgta gtgcaaacca   4140

caactgatga aggggagtca gggtcccaca gcgtgcgttt tgcagcccta gagcagcctg   4200

aggtggaaag gagaccatct cctcatgatg aagaagagtt tgaagtagaa gaggcagctg   4260

aagcccaggc agaacccaaa gatggttccc cagaggctcc agcttcccct gagagagaag   4320

aggttgcact ttctgaatat aagacagaaa cctatgacga ttacaaagat gagaccacca   4380

ttgacgactc catcatggac gctgacagcc tctgggtgga cactcaagat gatgatagga   4440

gcatcatgac agaacagtta gaaactattc ctaaagagga gaaagctgaa aaggaagctc   4500

ggagatcatc tcttgagaaa catagaaaag aaaagccttt taaaaccggg agaggcagaa   4560

tttccactcc tgaaagaaaa gtagctaaaa aggaacctag cacagtctcc agagatgaag   4620

tgagaaggaa aaaagcagtt tataagaagg ctgaacttgc taaaaaaaca gaagttcagg   4680

cccactctcc ctccaggaaa ttcattttaa aacctgctat caaatatact agaccaactc   4740

atctctcctg tgttaagcgg aaaaccacag cagcaggtgg ggaatcagct ctggctccca   4800

gtgtatttaa acaggcaaag gacaaagtct ctgacggagt aaccaagagc ccagaaaagc   4860

gctcttctct cccaagacct tcctccattc tccctcctcg gcgaggtgtg tcaggagaca   4920

gagatgagaa ttccttctct ctcaacagtt ctatctcttc ttcagcacgg cggaccacca   4980

ggtcagagcc aattcgcaga gcagggaaga gtggtacctc aacacccact acccctgggt   5040

ctactgccat cactcctggc accccaccaa gttattcttc acgcacacca ggcactcctg   5100

gaacccctag ctatcccagg acccctcaca caccaggaac ccccaagtct gccatcttgg   5160

tgccgagtga gaagaaggtc gccatcatac gtactcctcc aaaatctcct gcgactccca   5220

agcagcttcg gcttattaac caaccactgc cagacctgaa gaatgtcaaa tccaaaatcg   5280

gatcaacaga caacatcaaa taccagccta aaggggggca ggtacaaatt gttaccaaga   5340

aaatagacct aagccatgtg acatccaaat gtggctctct gaagaacatc cgccacaggc   5400

caggtggcgg acgtgtgaaa attgagagtg taaaactaga tttcaaagaa aaggcccaag   5460

ctaaagttgg ttctcttgat aatgctcatc atgtacctgg aggtggtaat gtcaagattg   5520

acagccaaaa gttgaacttc agagagcatg ctaaagcccg tgtggaccat ggggctgaga   5580

tcattacaca gtccccaggc agatccagcg tggcatcacc ccgacgactc agcaatgtct   5640

cctcgtctgg aagcatcaac ctgctcgaat ctcctcagct tgccactttg gctgaggatg   5700

tcactgctgc actcgctaag cagggcttgt gaatatttct catttagcat tgaaataata   5760

atatttaggc atgagctctt ggcaggagtg ggctctgagc agttgttata ttcattcttt   5820

ataaaccata aaataaataa tctcatcccc aaactgtagt aattgttaca attttctatt   5880

taaaaaatga atagtacatg cagaaattga cctgatttcc atttgcaaca ggaagacact   5940

ggctttacat gggttcaatt ggacaattat ttttgctctg ctctgttttg catggagtat   6000

tattatttta aaaattgcat ttttaccttt catgtgcctg aaggctatcc actacattct   6060

gaaggccttg ttaaaatcca agctgctcat ttcactattc tgtttctgag tgagaagata   6120

aaaactgccc attgtaactt atttcaggtt aaattaaacc aaggagtctg attgcaggaa   6180

gggaagagca tgtaagaaat aagttttttt aaagtgttat tttgtataaa tgggaagaaa   6240

gattcaatta agttattaac atttgggacc tggataatta tatcagagta tgtcagtcca   6300

ataaattatt taactaatta aaaaatagtt gcaaagcatt tgagctgtgg ttgaggaagt   6360

ggtgtaaaag tgcatccatt aggaatgatg cactttcatt aggatggact cgtgtctgat   6420

tagaatgtca gttgatcagc tagatttgtg tccacactac cagtttcaca ccccctttcc   6480

atctgtttga tacagtatta tagatataaa tatatatata tttctctgtg gccatttgtg   6540

atacttcctc atatacttga atattatact tctttattca cagtatctgt gtctcctgca   6600

ccctttggtg ttgcaatttt agatatgtga aagtagatgt tagcagggtt ctctccctat   6660

ttaaaaaaaa tacattaaaa aagacaaaaa attttagcat gaagttgctt tctgtaacaa   6720

ctcaaagccg taaccctgtt ttagtgccag atacaagtct ctcccgtgat gctagacaaa   6780

aaattatttt tctttgcttt caccaacatg gagtttgtgg gggtgggtcc agttatacat   6840

gaaagggttt acagattgtt ggtttaagat tatggattta tctcattttt aatcacagga   6900

tagtttgggg tttattccta ttattattca tgaaaccgac ttaagatttt ttctttattt   6960

ttcttttttt ttccatttgc taaagttgaa agttgaaact aactataata gtttgaaaca   7020

tgttttctca tttttccaaa tagtatctgt ttattaaatt ctctaataga agatgtttgt   7080

ctttcttacc caaagtaaag atcccctgat cagaaagaaa aaatacaata ctttgggaag   7140

ctatagctat aaaacacttg agacacagat atctaaatca gtttttttcc aagactccaa   7200

cattgcactc tgtaaagtaa cacactgtga tctagtatta tttatcagta gataatactg   7260

ttctgactgt atatacagtc tagaactcac aaatcaatta gttcctctca caaatcattc   7320

atcttagact tacaaataag gaatgaaata gtcaatggcc tgattaaggc aaagagctac   7380

caggctagat ggacactttt taaaaatttt atctgttctt tttcttgctc agggctggta   7440

ggttggatct gaaccattaa aatcaaatgg tccactaggc gtatgatctc tttgagccaa   7500

atcagttcct gaatataaag gaggaaatga tgaggatgta ctgaggcaac ggggaagtat   7560

agaaacatcc aagacaaaag ccaagggatg caaaggcaga gacacaggtg ctttttggtg   7620

acccagtgga tatggcaacc agtgtaactg ccatacaaga aaccctagga gcaaacccac   7680

accactcatt ctcagctaag agattttaca caggcaaacg tgtcttaaac catctataaa   7740

tcagttattt tatatgacag tcaaaacctt agaaacctta ggatcattat atctattttc   7800

tgcctattaa ttgctgtgag gtttgatttg accaatctgg gcaatttatt catcagcttc   7860

ccttgaagtg caccagaaaa tagaagaaag gtgtgtggag acttagggta ttttattaca   7920

tgttttcata gtcttaaata gtgattaaat ttctctagaa agaagttaac agctcattag   7980

aaaagtttta acctgtgaaa taagtatttt tctcaacatt ctttaaagtt tttatataag   8040

ttaacactag gtaaacattc tgcatactag aagtcagttt attacaaata catgtcaaaa   8100

ataaagatta tacaaggcac caaactacta gatttggcat taaaacaaat gtttatttct   8160

aatcacaaca aaattataat gaataaatgt tcttgctttg tatggaaata caattcttta   8220

ttaaagttaa cagaaaggaa ctgatcgttt gtaccagtaa aagagagaaa cacacaggtt   8280

aaatatcttc ttgtggggtt aaggggtaga acctatcttg ccttcactct caagataacg   8340

actcaaatta agctttttga gcaccactct tgtggggaca cacatacgct gatctaggaa   8400

tgaaatcttc gtggtctcaa ttctagatct actatgccag tttctctctg gctttagcct   8460

ttgagaacct gtataagaat acgtaagtaa tccagagctg tgaagagttt aaaggccaac   8520

ttctccagtg aactcaacct ctgggtcact tgcaaccaga aattggatac ctcataatga   8580

tgcaggaaag acccgagttc atgatgagtt tcaaaggcca cgttcattta ggaaccaact   8640

ctctctggat ttacctgctg agttccagca gcgtgatggg ctgacatccc acctacaagt   8700

atgacacctg tgtaacacca gctaggtacg gctggagaag gctgaagaga gaatgccatt   8760

aaatggaaga atgtactgat tgtagtgacc ttctccacac acacacacac acacacacac   8820

acacacacct acagtaatac agcaagcgtg gaataatcag ccaatatata acattccatc   8880

agtattttat taaggaaata acctgaatgt ggttgatttt gacatagctg caattacagt   8940

tttcttctat ttttcaagcc acaataagga aaataaacta ctcatggtct aaatactaga   9000

gataaagtag attcatggct tggtaaggaa attttaagca ttccttcaaa gattgacgtg   9060

ctaaaataag cattgatgtt ttgagttttt ttacacctag gatttttagc ttgggtgtgt   9120

aggtgaaggc caagactctc tgcaggaaaa agcttatttt caaactcaga aaataaaatg   9180

tcaatcataa aaatctactt caactttagc aaaaagaaaa aaaaatcaac aaaaagtata   9240

ctctgtatgc tgggattccg aggttccaac acactgttac aaatctgtgg ggggtttctt   9300

tcttctgata attctagagc ctgttaccat agaaaggcat ttcttcaatg gctggttgta   9360

gttagttcat gtttttcaat caaatttgca aatgtatttg ttgctgtata gtgattgttt   9420

tgcaaaataa aattgcttgt cacct                                         9445


<210>  601
<211>  1448
<212>  DNA
<213>  Human

<400>  601
aaaaatcgag gcggggctga gaggctgcgg cggctgacta ggttttcgga ccgcggcgcg     60

gcggggaaga gagactgcgg cgggagggcc aggccgtggg agagacgcgg gaaagtgcgg    120

gtcgcagagg cacttgacca ccccgcccta ggccgacccg gcggacgcgg cgtctggtgt    180

gcgggcgctg gggcgggtcc caggtctccc cgctgcgctg cttgaggctc agccatggcc    240

cagcagagag ccctgcccca gagcaaggag acgctgctgc agtcctacaa caagcggctg    300

aaggacgaca ttaagtccat catggacaac ttcaccgaga tcatcaagac cgccaagatt    360

gaggacgaga cgcaggtgtc acgggccact cagggtgaac aggacaatta cgagatgcat    420

gtgcgagccg ccaacatcgt ccgagccggc gagtccctga tgaagctggt gtccgacctc    480

aagcagttcc tgatcctcaa tgacttcccc tccgtgaacg aggccattga ccagcgcaac    540

cagcagctgc gcacactgca ggaggagtgc gaccggaagc tcatcacgct gcgagacgag    600

atctccattg acctctacga gctggaggag gagtattact cgtccagctc aagcctttgc    660

gaagctaatg acctgcctct gtgcgaagct tacgggaggc tggacctcga cacagactct    720

gctgatggcc tctcggcccc tctgctggcg tccccggagc ccagtgctgg ccccctacag    780

gtggcagccc ctgcccactc ccatgctggt ggccctggcc ccactgagca cgcctgagcc    840

tccggggcca cgcttcgttc tcaggaacaa aacctgaggc agccctttgg atgccctcac    900

agccttgctt ctctcagcct aggttcccat ttggggactt caggacccca gagccactag    960

gacttccttg ggaagcccgt tagcccaggg tgggtcccgc caggacagta gggaaacagt   1020

tgtttcccta gccatttccg aatagcccat cattccgagt catcatctct gtttgctgcc   1080

ttcctggcca gccaggtgga agaaagtttc caagctaggt ctggcccgtt ggggatctca   1140

gcagtggggc aggagggtgc ctgatttcgg ggagtcctga cccgagcctg ttgtcagagt   1200

tgggaggggc tctgagcagt gttgggcagg ccgggtctcc catcccgagg ccagcgttcc   1260

tgtgcagagc cccatccact ggttcttgcc ctgagccaca tatgtctgtg ccatgggctg   1320

agtgccacga caggcccgtg tgacagctgc tgcccacgca tgtggaagct aggtgggact   1380

cattcctaat tctgccgttg taatgagact tgattaaaac accgccactt ttttgcaaaa   1440

aaaaaaaa                                                            1448


<210>  602
<211>  2287
<212>  DNA
<213>  Human

<400>  602
ttctcgccac gcacctgcgt cagctcgctc tgcgcgtgcg ccggtggcgg gactctgggg     60

aaaatggctg cgtcttcgag tggtgagaag gagaaggagc ggctgggagg cggtttggga    120

gtggcgggtg gtaacagcac acgagagcgg ctgctgtctg cgcttgagga cttggaggtc    180

ctgtctaggg aacttataga aatgctggca atttcaagaa accaaaagtt gttacaggct    240

ggagaggaaa accaggtcct ggagttgtta attcaccgag atggggaatt tcaagaacta    300

atgaaattgg cacttaatca gggaaaaatt catcatgaaa tgcaagtttt agaaaaagaa    360

gtagagaaga gagacagtga tattcagcag ctacaaaaac agctaaagga agcagaacaa    420

atactggcaa cagctgttta ccaagcgaag gagaaactca agtcaataga aaaagcaaga    480

aaaggtgcta tctcctctga agaaataatt aagtatgcac ataggatcag tgcaagtaat    540

gctgtatgtg ctccactgac ctgggttcca ggggaccccc ggagacccta cccaactgat    600

ttagagatga gaagtgggtt actgggtcag atgaacaatc cttccactaa tggcgtgaat    660

ggccatttac caggagatgc acttgcagca ggaagattgc cagatgtcct tgctccacag    720

tatccatggc agtcaaatga catgtcgatg aatatgttac caccaaatca tagtagtgac    780

tttttgttgg aacctcctgg gcataataaa gaaaatgaag atgatgtaga gattatgtca    840

acggactcct caagcagtag tagtgagtct gattgaaaaa ccttaaaaga caatatacag    900

aattgaatac tgtagaattc tgtttcttta acagtagcag ggaaatgtaa actacaggtg    960

acaaaaaata cccaggtaaa cactggcttt ggtagaattg tgcagtcatt aaaagtcaaa   1020

attttttgac tttcttttta aagccaaaga ccatagtttt agttttaagc cactaggtag   1080

atatttaggg gaatagtcaa aatttactgt tgaaaaagca gttgctatgt gctttcttac   1140

cctgttctgt tccagttttg ctggatttgt acatagccat tctagaaata gagttgaggg   1200

aaattatcca tatacatatc actaataggc ttcttggaat tatttagaaa agcattttta   1260

aactggcagt ggatgactga ataggcatca tatttctttt tgtgtgtcat ttaaaagtaa   1320

caaaaactgc catttgacag taaaggctct tggcttctgt tggaggcatg ggaaattgtc   1380

tcaatttgta cagtttgtaa ttgtaatttt tgtaaataaa tttgtttgta cattgtatgc   1440

ttttttttta gtttaaatat actgtcagtg taggtaggaa attatttctg taaatccagt   1500

tgcattttat aatacttgag tgactaactg aattgaaacc tattacaatt aatagggttc   1560

tcaaaggcct attcctatta gaagaaataa ttttttttaa taattgaaaa aatttaccac   1620

agccttgtct gattttaaga atagattgtg tgaagattta gaatggaaag caaccatttc   1680

ttcccttcac cttcctcttc ttacagttcc ccaggagtca tttttaacca cttttaattt   1740

ctgttggtaa cctctgtgtt taggtaatat gcttatacaa ctatttcttg atgtatcagt   1800

tttagacaat gtatcttctg atttcaaagg taatacaaca tttaatgtga aacatttagt   1860

gaatacagta aaggagaaaa taaaattgtt agcattctac ccagagataa tatcaattca   1920

tattgtagtg tagatttttt taaagttcac atacactttt ttgtaaaatg agaataatgt   1980

ttatttcctg agatactgct gtatttttta attgctaatc tgtattcttc aaatgaactg   2040

agaattccat ttttccatca ttttttcctt ttgattattt tcgatctcta gaaaaattgg   2100

aaaataggag attaatctta tattttcacc atctagaatt aaggacatac aatgtttgaa   2160

tgtctttccc tccagggtta tttttaggaa tggactaaca caatatctaa ttttaacctt   2220

gccttgtccg tatactagga atattgatcc atgtgtatac attcttgaaa gatttacttt   2280

aatggct                                                             2287


<210>  603
<211>  1894
<212>  DNA
<213>  Human

<400>  603
cggcgtgccc tggggcggcg cgggcgcagg ggcgcgtgcg cggcgggctg tcgttggctg     60

gagcagcggc tgcgcgggtc gcggtgctgt gaggtctgcg ggcgctggca aatccggccc    120

aggatgtaga gctggcagtg cctgacggcg cgtctgacgc ggagttgggt ggggtagaga    180

gtagggggcg gtagtcgggg gtggtgggag aaggaggagg cggcgaatca cttataaatg    240

gcgccgaagc aggacccgaa gcctaaattc caggagggtg agcgagtgct gtgctttcat    300

gggcctcttc tttatgaagc aaagtgtgta aaggttgcca taaaggacaa acaagtgaaa    360

tacttcatac attacagtgg ttggaataaa aattgggatg aatgggttcc ggagagcaga    420

gtactcaaat acgtggacac caatttgcag aaacagcgag aacttcaaaa agccaatcag    480

gagcagtatg cagaggggaa gatgagaggg gctgccccag gaaagaagac atctggtctg    540

caacagaaaa atgttgaagt gaaaacgaaa aagaacaaac agaaaacacc tggaaatgga    600

gatggtggca gtaccagtga gacccctcag cctcctcgga agaaaagggc ccgggtagat    660

cctactgttg aaaatgagga aacattcatg aacagagttg aagttaaagt aaagattcct    720

gaagagctaa aaccgtggct tgttgatgac tgggacttaa ttaccaggca aaaacagctc    780

ttttatcttc ctgccaagaa gaatgtggat tccattcttg aggattatgc aaattacaag    840

aaatctcgtg gaaacacaga taataaggag tatgcggtta atgaagttgt ggcagggata    900

aaagaatact tcaacgtaat gttgggtacc cagctactct ataaatttga gagaccacag    960

tatgctgaaa ttcttgcaga tcatcccgat gcacccatgt cccaggtgta tggagcgcca   1020

catctcctga gattatttgt acgaattgga gcaatgttgg cttatacacc tctggatgag   1080

aagagccttg ctttattact caattatctt cacgatttcc taaagtacct ggcaaagaat   1140

tctgcaactt tgttcagtgc cagcgattat gaagtggctc ctcctgagta ccatcggaaa   1200

gctgtgtgag aggcactctc actcacttat gtttggatct ccgtaaacac atttttgttc   1260

ttagtctatc tcttgtacaa acgatgtgct ttgaagatgt tagtgtataa caattgatgt   1320

ttgttttctg tttgatttta aacagagaaa aaataaaagg gggtaatagc tccttttttc   1380

ttctttcttt ttttttttca tttcaaaatt gctgccagtg ttttcaatga tggacaacag   1440

agggatatgc tgtagagtgt tttattgcct agttgacaaa gctgcttttg aatgctggtg   1500

gttctattcc tttgacacta cgcactttta taatacatgt taatgctata tgacaaaatg   1560

ctctgattcc tagtgccaaa ggttcaattc agtgtatata actgaacaca ctcatccatt   1620

tgtgcttttg ttttttttta tggtgcttaa agtaaagagc ccatcctttg caagtcatcc   1680

atgttgttac ttaggcattt tatcttggct caaattgttg aagaatggtg gcttgtttca   1740

tggtttttgt atttgtgtct aatgcacgtt ttaacatgat agacgcaatg cattgtgtag   1800

ctagttttct ggaaaagtca atcttttagg aattgttttt cagatcttca ataaattttt   1860

tctttaaatt tcaaagaaca aaaaaaaaaa aaaa                               1894


<210>  604
<211>  1501
<212>  DNA
<213>  Human

<400>  604
agtcccggaa ctgctagaac gaaccattcg catatggagg gggtgaccca ccatctcaga     60

acattaaaaa agggaaagaa tcccctggtg aactacagtg aaagtcttat tgagcattta    120

aatggaaata aaaatattca gtggacctaa tgaagagtag atgactttcc cttctgtccc    180

ctccccgaca ggcactcatg gtaccggcgc cggcgcagct gtgactgtcg ctgcagacgg    240

aaactgactg gggtcaattc aagtcatgca ggctgtgaga aacgcggggt cgcggttcct    300

gcggtcctgg acttggcccc agacagccgg cagggtcgtg gccagaacgc cggccgggac    360

catctgcaca ggcgctcgac agctccaaga cgctgcggcc aagcagaaag ttgaacagaa    420

cgcggctccc agccacacca agttcagcat ttaccctccc attccaggag aggagagctc    480

tctgaggtgg gcaggaaaga aatttgagga gatcccaatt gcacacatta aagcatccca    540

caacaacaca cagatccagg tagtctctgc tagtaatgag ccccttgcct ttgcttcctg    600

tggcacagag ggatttcgga atgccaagaa gggcacaggc atcgcagcac agacagcagg    660

catagccgca gcggcgagag ctaaacaaaa gggcgtgatc cacatccgag ttgtggtgaa    720

aggcctgggg ccaggacgct tgtctgccat gcacggactg atcatgggcg gcctggaagt    780

gatctcaatc acagacaaca ccccaatccc acacaacggc tgccgcccca ggaaggctcg    840

gaagctgtga tgggaaggag gcctgcactt ggacctgacc tcaagcctca gctccagtgg    900

gaccttgtaa aatgctccct gtcagagctc tccagaatat gcttgttgga gatccttcag    960

gcagtaaggg agagttttgc ctccttacac agtggccttt gcttgcacct ccagctggag   1020

atgggtgtgc cccagaagta agctttgcat ctcttacaag aggggagcta caggggcagc   1080

cgtggcctag gcccaaactc tgctctgaga aaataaatat ctgtaccacc tgtcataatt   1140

ttgagatttt ttgctttcag agttacgtaa ttcctaattc ctcttgaaaa agagagtgtg   1200

aaatgaggtg aggcctcaga tgaaagtaaa atataaatgt gagttgctat ttaccagaca   1260

cttctggttt cagatatttc ttttctagcc ccttacccaa gatttctaga gctaatccta   1320

gtaacttttc ttattaatga cttataattt ggccccaaat tggagctttt tgccacctac   1380

ctctggattc tgatggattt cgccattatg ggcatgttta aagttagccc taaacacagg   1440

attttctaca agtggacagt caaactcccc acactaaagt ggcagtcatc gtttacactc   1500

c                                                                   1501


<210>  605
<211>  2442
<212>  DNA
<213>  Human

<400>  605
gtgcgtcaca gaatggcctc ggacacccag gcagtccctg acgtgtcggg gaggagccgg     60

gcgcggaggt acgctgagtg gagctcgggg ctgcgtaggg gagctgagcc gagcggctgg    120

gcgggcctgg ccgggccagc ggaggggaga cgtcggttga gcggcggcga acatgcgctt    180

ttgacacatt ggaggctttc ttgatcatgg atggtgaaga tataccagat ttttcaagtt    240

taaaggagga aactgcttat tggaaggaac tttccttgaa gtataagcaa agcttccagg    300

aagctcggga tgagctagtt gaattccagg aaggaagcag agaattagaa gcagagttgg    360

aggcacaatt agtacaggct gaacaaagaa atagagactt gcaggctgat aaccaaagac    420

tgaaatatga agtggaggca ttaaaggaga agctagagca tcaatatgca cagagctata    480

agcaggtctc agtgttagaa gatgatttaa gtcagactcg ggccattaag gagcagttgc    540

ataagtatgt gagagagctg gagcaggcca acgacgacct ggagcgagcc aaaagggcaa    600

caatagtttc actggaagac tttgaacaaa ggctaaacca ggccattgaa cgaaatgcat    660

ttttagaaag tgaacttgat gaaaaggaat ctttgttggt ctctgtacag aggttaaagg    720

atgaagcaag agatttaagg caagaactag cagttcggga aagacaacag gaagtaacta    780

gaaagtcggc tcctagctct ccaactctag actgtgaaaa gatggactcc gccgtccaag    840

catcactttc tttgccagct acccctgttg gcaaaggaac ggagaacact tttccttcac    900

cgaaagctat accaaatggt tttggtacca gtccactaac tccctctgct aggatatcag    960

cactaaacat cgtgggggat ctcttacgga aagtaggggc tttagaatcc aaattagcag   1020

cttgcaggaa ttttgcaaag gaccaagcat cacgaaaatc ctatatttca gggaatgtta   1080

actgtggggt gctgaatggc aatggcacaa agttctctcg atcagggcat acatctttct   1140

tcgacaaagg gcaagaaaaa gtcatatttc ccacgttgtt catggggcag taaacggctt   1200

tgaccccgct cctcctcctc ctggtctggg ctcctcgcgt ccatcgtcag cgccgggtat   1260

gctgcctctc agtgtgtgag tgcctagcct ccaggtgggg gctcctgccc tcctccaaca   1320

acccaggaca cccacgcctc acccctcggt gcctgggccc agccccgtgc ccctccgtct   1380

gcctccgcac ggctggcaga gggcaggctg catgcagtgg cggctactgg gccctgccca   1440

gccccggaac tctgcgcgat atcaatactg gctattttct cttctcgccg tagtgccgtt   1500

ggtttcacat gattgcactt ttgtgggtcg caaggtgata catacgtgta ttacttggtc   1560

actggatgca gaagtaccca ttcatcacac ctgccccata gcccccactc tgctgtactg   1620

ataggattta gttgtgtttt aggacattgc aaatcttcta gaagttctcc cccaaatcag   1680

gtcaatgtgt gccctcctga gctcccaccc aggcatctcc agtgctcatg atcatgtgtc   1740

ccccaactcc acccctcaca gtttgggcct gtttctggca aagagtcagg aaggttactg   1800

aattagggaa cattttctgc accttctgat tttacttaag cagctaccat tccatggact   1860

tgcctcccag agcagcacaa tgcccgtctg agccccacgt ggcaggagcc tctgggacgg   1920

ggcacacaca ggcccagcct ctgtgctgtc tcctcctccg tgcgcctcag actcggggtg   1980

agggaggcgg gcagcctctc gccagccttc ccgtccttca gttcaacgac atctttggag   2040

tgtttttgtt ttctcttcca agggccgtcc cgttgtgtta ggaagggtga gtggctggtt   2100

ccagggtggg ccggtgccag ctccggggtg gactgaacag cggcggctgt ccctgtgcat   2160

cctttgatta ctctcatgct gcatttactg tttacatttg ttttattgta cataggtttg   2220

taaacattat tgcctgagat atttgtatat aacttgggct ttgtagcttt tatttattca   2280

gaacgcatac ggcatgttaa tgactctgat ggtgtcctcc tctgggcagc tgtataggat   2340

catcatgtgg ttacaaaaaa tacttccctc aaaaaaattc ttttaatgtg gaaacaataa   2400

atttcacaga aaaaaaggat tgacgttgct ttaaaaaaaa aa                      2442


<210>  606
<211>  2100
<212>  DNA
<213>  Human

<400>  606
cggccccccg cattccccgc ccccacctcc ccgccttgtt gtccaacttc tcccggagca     60

gccggagagc aggcgtcggg acgcagcaaa gagaggagag accccagagt cagaaggagt    120

gagaaccctg acccctaatc ccactgcatc cagccaatag gagcccagcc accatggcgg    180

agctgcagga ggtgcagatc acagaggaga agccactgtt gccaggacag acgcctgagg    240

cggccaagac tcactctgtg gagacaccat acggctctgt cactttcact gtctatggca    300

cccccaaacc caaacgccca gcgatcctta cctaccacga tgtgggactc aactataaat    360

cttgcttcca gccactgttt cagttcgagg acatgcagga aatcattcag aactttgtgc    420

gggttcatgt ggatgcccct ggaatggaag agggagcccc tgtgttccct ttgggatatc    480

agtacccatc tctggaccag cttgcagaca tgatcccttg cgtcctgcag tacctaaatt    540

tctctacaat aattggagtt ggtgttggag ctggagccta catcctggcg agatatgctc    600

ttaaccaccc ggacactgtt gaaggtcttg tcctcatcaa cattgatccc aatgccaagg    660

gttggatgga ttgggcagcc cacaagctaa caggcctcac ctcttccatt ccggagatga    720

tccttggaca tcttttcagc caggaagagc tctctggaaa ttctgagttg atacaaaagt    780

acagaaatat cattacacat gcacccaacc tggataacat tgaattgtac tggaacagct    840

acaacaaccg ccgagacctg aactttgagc gtggaggtga tatcaccctc aggtgtcctg    900

tgatgctggt ggtaggagac caagcacctc atgaagatgc agtggtggaa tgtaactcaa    960

aactggaccc cacccagacc tcgttcctca agatggctga ctccggaggt cagccccagc   1020

tgactcagcc aggcaagctg accgaggcct tcaagtactt cctgcaaggc atgggctaca   1080

tggcctcatc ctgcatgact cgcctgtccc ggtctcgtac agcctctctg accagtgcag   1140

catccgttga tggcaaccgg tcccgctctc gcaccctgtc ccagagcagc gagtctggaa   1200

ctctttcttc ggggcccccg gggcacacca tggaggtctc ctgttgaatg gcccttgttg   1260

ccctagagtg ggacccagcc ctcacctccc ccagagctaa cctgggaggt gctgaagggg   1320

cattgggcca ccgtaagcaa gggaaaaagg gcagatcatg cggggagatg accttgatct   1380

ttgattgcta ccctaacctt gacctttaac ccgtgattcc ccccagctcc tggaagagat   1440

gtcctaatat ctcttaggga cccagacccc taaattctcc tcctccccca ttttgatgtt   1500

aaggtggaga gggcatatgc atcctctgtc ctgatctagg tgtctatagc tgaggggtaa   1560

gaggttgttg tagttgtcct ggtgcctcca tcagactctc cctacttgtc ccatatttgc   1620

aaggggaggg gatttggggc tggggctcca ttcaccaaag ctgaggtggc ttctcattaa   1680

ccctttagga ctctgaaggg tatggaccta cgtgaatgtg tgtcaggggg agacttgctg   1740

gtgggttagt ggtcctcagg atgtgataga aacatccagt gtaaaaagga agttggaatg   1800

ggagttggcg ggcagtgaac gagtgtgggg aaggattggt gctggggcaa caggaagggg   1860

cctggggccg tttggctgca ctaactttgg tagctcagtg tgcatctaga gtgggactgg   1920

ggagggagct aagcttgggc tgggctgctt ggggcttggc atagggtgga aagggctacc   1980

ctggggctct gaccacactg tagtatgtgt ggagggtgcc ctcccgtctc ccacaacttc   2040

tgctataaca ataaactgta gaggaatctg agtaccgtta aaaaaaaaaa aaaaaaaaaa   2100


<210>  607
<211>  3721
<212>  DNA
<213>  Human

<400>  607
aaaagggccg gcgccctggt gctgccgcag tgcctcccgc cccgtcccgg cctcgcgcac     60

ctgctcaggc catgatgagc ttcggcggcg cggacgcgct gctgggcgcc ccgttcgcgc    120

cgctgcatgg cggcggcagc ctccactacg cgctagcccg aaagggtggc gcaggcggga    180

cgcgctccgc cgctggctcc tccagcggct tccactcgtg gacacggacg tccgtgagct    240

ccgtgtccgc ctcgcccagc cgcttccgtg gcgcaggcgc cgcctcaagc accgactcgc    300

tggacacgct gagcaacggg ccggagggct gcatggtggc ggtggccacc tcacgcagtg    360

agaaggagca gctgcaggcg ctgaacgacc gcttcgccgg gtacatcgac aaggtgcggc    420

agctggaggc gcacaaccgc agcctggagg gcgaggctgc ggcgctgcgg cagcagcagg    480

cgggccgctc cgctatgggc gagctgtacg agcgcgaggt ccgcgagatg cgcggcgcgg    540

tgctgcgcct gggcgcggcg cgcggtcagc tacgcctgga gcaggagcac ctgctcgagg    600

acatcgcgca cgtgcgccag cgcctagacg acgaggcccg gcagcgagag gaggccgagg    660

cggcggcccg cgcgctggcg cgcttcgcgc aggaggccga ggcggcgcgc gtggacctgc    720

agaagaaggc gcaggcgctg caggaggagt gcggctacct gcggcgccac caccaggaag    780

aggtgggcga gctgctcggc cagatccagg gctccggcgc cgcgcaggcg cagatgcagg    840

ccgagacgcg cgacgccctg aagtgcgacg tgacgtcggc gctgcgcgag attcgcgcgc    900

agcttgaagg ccacgcggtg cagagcacgc tgcagtccga ggagtggttc cgagtgaggc    960

tggaccgact gtcggaggca gccaaggtga acacagacgc tatgcgctca gcgcaggagg   1020

agataactga gtaccggcgt cagctgcagg ccaggaccac agagctggag gcactgaaaa   1080

gcaccaagga ctcactggag aggcagcgct ctgagctgga ggaccgtcat caggccgaca   1140

ttgcctccta ccaggaagcc attcagcagc tggacgctga gctgaggaac accaagtggg   1200

agatggccgc ccagctgcga gaataccagg acctgctcaa tgtcaagatg gctctggata   1260

tagagatagc cgcttacaga aaactcctgg aaggtgaaga gtgtcggatt ggctttggcc   1320

caattccttt ctcgcttcca gaaggactcc ccaaaattcc ctctgtgtcc actcacataa   1380

aggtgaaaag cgaagagaag atcaaagtgg tggagaagtc tgagaaagaa actgtgattg   1440

tggaggaaca gacagaggag acccaagtga ctgaagaagt gactgaagaa gaggagaaag   1500

aggccaaaga ggaggagggc aaggaggaag aagggggtga agaagaggag gcagaagggg   1560

gagaagaaga aacaaagtct cccccagcag aagaggctgc atccccagag aaggaagcca   1620

agtcaccagt aaaggaagag gcaaagtcac cggctgaggc caagtcccca gagaaggagg   1680

aagcaaaatc cccagccgaa gtcaagtccc ctgagaaggc caagtctcca gcaaaggaag   1740

aggcaaagtc accgcctgag gccaagtccc cagagaagga ggaagcaaaa tctccagctg   1800

aggtcaagtc ccccgagaag gccaagtccc cagcaaagga agaggcaaag tcaccggctg   1860

aggccaagtc tccagagaag gccaagtccc cagtgaagga agaagcaaag tcaccggctg   1920

aggccaagtc cccagtgaag gaagaagcaa aatctccagc tgaggtcaag tccccggaaa   1980

aggccaagtc tccaacgaag gaggaagcaa agtcccctga gaaggccaag tccccagaga   2040

aggaagaggc caagtcccct gagaaggcca agtccccagt gaaggcagaa gcaaagtccc   2100

ctgagaaggc caagtcccca gtgaaggcag aagcaaagtc ccctgagaag gccaagtccc   2160

cagtgaagga agaagcaaag tcccctgaga aggccaagtc cccagtgaag gaagaagcaa   2220

agtcccctga gaaggccaag tccccagtga aggaagaagc aaagaccccc gagaaggcca   2280

agtccccagt gaaggaagaa gctaagtccc cagagaaggc caagtcccca gagaaggcca   2340

agactcttga tgtgaagtct ccagaagcca agactccagc gaaggaggaa gcaaggtccc   2400

ctgcagacaa attccctgaa aaggccaaaa gccctgtcaa ggaggaggtc aagtccccag   2460

agaaggcgaa atctcccctg aaggaggatg ccaaggcccc tgagaaggag atcccaaaaa   2520

aggaagaggt gaagtcccca gtgaaggagg aggagaagcc ccaggaggtg aaagtcaaag   2580

agcccccaaa gaaggcagag gaagagaaag cccctgccac accaaaaaca gaggagaaga   2640

aggacagcaa gaaagaggag gcacccaaga aggaggctcc aaagcccaag gtggaggaga   2700

agaaggaacc tgctgtcgaa aagcccaaag aatccaaagt tgaagccaag aaggaagagg   2760

ctgaagataa gaaaaaagtc cccaccccag agaaggaggc tcctgccaag gtggaggtga   2820

aggaagacgc taaacccaaa gaaaagacag aggtagccaa gaaggaacca gatgatgcca   2880

aggccaagga acccagcaaa ccagcagaga agaaggaggc agcaccggag aaaaaagaca   2940

ccaaggagga gaaggccaag aagcctgagg agaaacccaa gacagaggcc aaagccaagg   3000

aagatgacaa gaccctctca aaagagccta gcaagcctaa ggcagaaaag gctgaaaaat   3060

cctccagcac agaccaaaaa gacagcaagc ctccagagaa ggccacagaa gacaaggccg   3120

ccaaggggaa gtaaggcagg gagaaaggaa catccggaac agccaaagaa actcagaaga   3180

gtcccggagc tcaaggatca gagtaacaca attttcactt tttctgtctt tatgtaagaa   3240

gaaactgctt agatgacggg gcctccttct tcaaacagga atttctgtta gcaatatgtt   3300

agcaagagag ggcactccca ggcccctgcc cccaggccct ccccaggcga tggacaatta   3360

tgatagctta tgtagctgaa tgtgatacat gccgaatgcc acacgtaaac acttgactat   3420

aaaaactgcc cccctccttt ccaaataagt gcatttattg cctctatgtg caactgacag   3480

atgaccgcaa taatgaatga gcagttagaa atacattatg cttgagatgt cttaacctat   3540

tcccaaatgc cttctgtttt ccaaaggagt ggtcaagccc ttgcccagag ctctctattc   3600

tggaagagcg gtccaggtgg ggccggggac tggccactga attatgccag ggcgcacttt   3660

ccactggagt tcactttcaa ttgcttctgt gcaataaaac caagtgctta taaaatgaaa   3720

a                                                                   3721


<210>  608
<211>  11529
<212>  DNA
<213>  Human

<400>  608
cgggggaccc cacttgtgtg cagcctagac gctggttcag ggagtcgtac atggaagcct     60

tgcggaaccc catgcccctg ggcagctctg aggaggccct cggggacctg gcctgcagct    120

ccctgactgg agccagcagg gacctgggga ctggggcagt agccagtggg acccaggagg    180

aaacctctgg cccccgggga gacccccaac agaccccaag tctagagaag gagaggcaca    240

cacccagccg gacaggtcca ggagctgcag ggcggactct tcccaggaga tctcggtcct    300

gggaaagggc acccagaagc tccagagggg cccaggctgc agcctgccac acctcccacc    360

actcagcagg ctccaggcct gggggccacc taggaggaca agctgtgggg accccaaact    420

gtgtcccagt agagggtccc ggctgcacca aagaggaaga cgttcttgca tcctcagcct    480

gtgtcagcac agacggcggc agcctccatt gccacaaccc cagcgggcct tccgatgtgc    540

ctgcccggca gccacacccc gagcaagaag ggtggccacc cggcacagga gacttcccca    600

gccaggtgcc caagcaggtg ctggacgtca gtcaggagct gctgcagtcc ggggtcgtca    660

ccctcccagg gacccgagac cgtcatggca gagcagtggt gcaggtccgc accaggagcc    720

tgctctggac cagggaacac tcgtcctgtg ctgagctgac ccgcctgctg ctgtacttcc    780

atagcatccc caggaaagag gtccgggacc tggggctggt tgtcctggtg gatgcacgca    840

ggagtccagc tgcccctgcc gtctcccagg ccctctcagg attgcagaac aacacatctc    900

ctataattca tagtatcttg ctgttggtag ataaagaatc tgcatttagg cctgacaagg    960

atgcaataat tcagtgtgag gtcgtgagct ccctgaaggc cgtgcacaaa tttgttgaca   1020

gctgccagct gaccgcagac ctcgacggct cctttcccta cagccatggt gactggatct   1080

gcttccgtca gaggctggaa cacttcgctg caaactgtga agaagccatc attttcctac   1140

agaattcatt ctgctccctg aacacccaca gaaccccaag aacagcccag gaagtcgccg   1200

agttaattga ccagcatgag acgatgatga agcttgtcct ggaagaccca ctgcttgtgt   1260

ctctcaggct ggaggggggc accgtcctgg cgcggctgag gagagaagag cttggcacag   1320

aagacagccg ggacaccctg gaggccgcca caagcctgta cgaccgagtg gatgaggagg   1380

tgcacaggct ggtcctcacc tcgaacaatc gtctccagca gctggagcac ctccgggagc   1440

tggcgtcact cctggaaggg aatgaccagc aatcctgcca gaaaggacta cagctggcga   1500

aggagaaccc gcaacgtaca gaggaaatgg tccaggattt cagaaggggc ctgagcgccg   1560

tggtcagcca ggctgagtgc agggagggag agctggccag gtggacccgc tcgtccgagt   1620

tgtgcgagac ggtgagcagc tggatggggc ccctggaccc ggaggcttgt ccctcctcac   1680

ccgtggctga gtgtttgagg agctgtcacc aggaggctac ctcggtggct gcagaggcct   1740

tccccggggc aggtgtggca gtgctgaagc ctcatgccct ggggaaaccg tgggcatcac   1800

agcaagacct gtggctgcag tacccccaga cccggctccg tctggaagag gccctttctg   1860

aggctgcccc agaccccagc ttaccgcccc ttgcccagag ccccccaaag catgagcgtg   1920

cccaggaggc catgaggagg caccagaagc caccctcatt ccccagcacg gacagtgggg   1980

gtggtgcctg ggaacctgcg caaccactgt ccggcctccc tggacgagcg cttctgtgtg   2040

gacaggacgg ggagaccctg cgcccagggc tgtgtgctct gtgggaccca ctgtccctcc   2100

tcaggggcct tccaggggca ggggccacca cggcccacct ggaggacagc tctgcctgtt   2160

cctctgagcc cacccagacc ctggccagcc gccccaggaa acatccccag aagaaaatga   2220

taaagaaaac gcaaagtttc gagatacctc agcccgacag tggccccagg gactcctgcc   2280

agccagacca tactagtgtc ttcagcaagg gcctggaggt aaccagcact gtagccacag   2340

agaagaagct cccgctgtgg cagcatgcca ggagcccccc ggtcactcag agccggagtc   2400

tgtcctcccc ctcggggctc caccctgctg aggaggatgg gaggcagcag gtgggcagca   2460

gccgactgag gcacatcatg gccgagatga tcgccacaga gagggagtac attcggtgct   2520

taggatacgt cattgacaac tattttccag aaatggaaag aatggacttg ccccagggcc   2580

ttcgagggaa gcaccacgtt attttcggca acttggagaa gctccacgac ttccaccagc   2640

agcacttcct ccgggagctg gagcgctgcc agcactgccc cttggccgtg ggccgcagtt   2700

tcctgagaca cgaagagcag tttgggatgt acgtgatcta cagcaaaaac aagccgcagt   2760

cggatgccct gctcagcagc catggcaacg ccttcttcaa ggacaagcag cgggagctag   2820

gtgacaaaat ggacctggcc tcctacctgc tgcggcccgt gcagcgtgtg gccaagtacg   2880

cgctgctact ccaggacctg ctcaaggagg ccagctgtgg cctggcccag gggcaggagc   2940

tgggcgagct ccgagccgcc gaggtcgtgg tctgcttcca gctgcgtcac ggcaatgacc   3000

tgctggccat ggacgccatc cgcggctgtg acgtgaattt gaaggaacag gggcagctga   3060

gatgccggga tgagtttatc gtttgctgcg ggaggaagaa gtatctgagg catgtgttcc   3120

tctttgaaga cctcatcctg tttagcaaga cccagaaggt ggagggcagc cacgacgtct   3180

acctgtacaa gcagtccttc aagacggccg agatcgggat gacagagaac gtcggggaca   3240

gtggcttgag gtttgagatt tggtttcgca ggcggcggaa atctcaggac acctacattc   3300

tccaagcaag ctcggcagag gtcaagagtg catggaccga tgtcataggg aggatcctgt   3360

ggcggcaggc actaaagagc agagaactca gaatccaaga aatggcatcc atgggtatag   3420

gcaaccagcc attcatggat gtcaagccca gagaccggac ccctgactgt gcagtgataa   3480

gcgaccgggc tcccaaatgt gcagtgatga gcgaccgagt ccccgacagc atcgtcaagg   3540

gcacagagtc acaaatgaga gggtccacag cggtgtcctc ctctgaccac gccgccccct   3600

tcaagcgacc acactccacc atctcagaca gcagcacctc ctcttctagc agccagtcct   3660

cctccatcct ggggtcgctg ggcctgcttg tgtcctccag cccagcccac ccgggcctat   3720

ggagccctgc ccacagcccc tggtcatctg atatcagagc ctgcgtcgag gaagatgagc   3780

cagagccaga actagagacg ggcacccagg ctgcagtgtg tgagggggct cctgctgtgc   3840

tgctgagccg cacacgccag gcctgatgac tgtcagggtg gcagtgccca tcatgtggct   3900

agaacaatac agagggagca gcacgccagg cctgatgact ctgggggtgg cggtgcccat   3960

cgcgtggctg gaacgatcca gagggaatag cacagcaggt gtccaggtat ttcccaggat   4020

tttagacatt ccctaacatt ttcaaacaaa tttataattt tgtcttattt aaaaaacaaa   4080

ccttccactt ccacccaaga caacagcata ggaaacagac ctaaaacaag acaaaaaaag   4140

actaaacatg aaacaaaaga tgtcaagaca caagacattt ggcaacaaag gaccgcgatc   4200

cctgagagac aggaaaacgg gaggtgagcc cggtgatggc ctcagacctc cctccgcctt   4260

gagagtttgc aggcctcagt gcagggaggg gcccaggaag agcccagcag cctccgtgag   4320

ttgaagagac caagtcagca ggagttggca ggtcagagtg ccagagagag atgcctgcat   4380

ggggaaagac tcaccagatc agcccctcca gcacctagtg ggttgctacc cattcgcaca   4440

ctcaaacagg gaggctacca aggctgggag caacctttga aaagaccaaa gatcaattcc   4500

tggtactcat gtgggctggg gacaggaccc gttcccacca gccagactag ggaaactctc   4560

aatagatcaa ttcctgatac tcatgtgggc tggggacagg acccactccc accagccaga   4620

ctaggaaaac tcccaatctg tgagcattag gtggagttct cagaaaatct tgcctcagga   4680

atggggataa ttagccctag actgagccct gctcctgact cgcctacaaa atcataaaag   4740

caagacctaa aatgatcaaa ccattcccag ataattcact ttatcccaga acaaagctcc   4800

agatgatcta ggggttacca aagtgtccac accctgcaag gtaaactcac agtgcctgac   4860

ctcggagtgc caggcgtgca gaggagcagc caagggcaaa cactccaagg agagtcgcct   4920

ggcaaagcca accacccaga gccagcgtct gtgctagaat cacagaattc aaactgtggc   4980

tgaaatcgca gcccaggcgt ccagaaagtt aaagttaaga acctataatc ccagcacttt   5040

gggaggccga ggcaggcgga tcacgaggtc aggagatcaa gaccatcctg gctaacatgg   5100

tgaaaccccg cctactaaaa atacaaaaaa ttagccgggc atggtgttgg ccgcctgtag   5160

tcccagctac ttgggaggct gaggcaggag aatggcatga acccgggagg cggagtttgc   5220

agtgagctga gatcacgcca ctgcactcca gcctgggcga cagagcaaga ctctgtctca   5280

caaaaaaggt taagaaatga cttaatggaa gagattcaga agacccagac cgaccttaca   5340

gggatgagaa actacaatat tgacagtgga aactatcctg gatggggtaa cagattggat   5400

ttcacagaag agaccatgag gcaccttgaa gacacatcag tggaaactat ttgcatttgt   5460

tgggcctcca gagagacaga accaatagga gatagctaga tatatataca gacagataga   5520

tagatagata gatcgataga tagatagata gatagataga tagatagata gactgacaga   5580

cagatgagag gggccttagg ggcattggct gacacaattt tggcaggtca agagccccac   5640

aataggccat ccacaagctg gagacccaag gaagctgcta gtgtgcccag tccgagtcct   5700

aaagcctcag agccagggaa gccagtggtg taattctcag aggccaaagg cctgagaacc   5760

tgggggccac tggtataagt ctgagtccat agacccagtg aactccaaac acaagagata   5820

cgagtgcaca tcataatcaa attgcatata accagtgata aacagaaaat cctaaaacca   5880

gtcagaggac aagggcatgt tctgttggga ggcacaaagc tgatgaggat ggctgactcc   5940

tcaggagcag catgggtgag aggcagtgga atgtactaag gagaaaactg ccaaattcac   6000

attctgtacc tgacaaaatc tttccgaagc gatggtgaca taaagacatt ttcatacaca   6060

cagaaactaa gagtttcatc cccagcagac ctgcactaca agaaatgtta aatgatgtgc   6120

ttcagggaaa agaaaaatga agagcatgtg caccatccag gattttcctc gttatttaaa   6180

tccctttagc ccatctccca tttgccccaa ggaatgagtg ctggcagtga gctgcacttt   6240

ttttttctct aaacgggaaa tgggttaaaa gatgagtggc ttggccgggt gcggtggctc   6300

atgtctctaa tcccagcact ttgggaggct gaggccagag gatcacttga cttgagccca   6360

ggaactgggg ggtcatgctg ggaaacatgg caagaccgca tctctattaa aaataaataa   6420

aagttaactg actgtttaaa caaaagtatt aacgtatctg cggtttgtac tatacgcaca   6480

ggtaaactgt gtgaccacag cagcgtgatg gctgggagac gctggatgtg atacgtgaag   6540

tgaggggtat cacttgaagg tagattgtgg taagctaaag atgtactgat aaacccttga   6600

aacacccact aacaaagaat tacagctaat agaccaacag aggagataaa atggaatttt   6660

taaaaatcca gtccaaaaat acgtagagaa agagggaaag ggaagaatgg acttgggggc   6720

gacacagaag acaagtggag agagactgaa gcagccactg gccatcacag caaacacaag   6780

cagggcgcag gacgccggca agccacagac aggcctgctc tctgaattgg tgaccacatg   6840

agtaacttca cgggtctgtt ctatgtccag agttgtcaaa ctgcatgctt taaagatgtg   6900

cagtggatcg tatgtcgctt aaatcccaac aaagcagtat ttttttaaag tacaatcatg   6960

cacacagcac ttcccctggg aggcaggggc tgtgcccaca gaagtcgtta cctctgcgtc   7020

ctgagtatgg acagccacca tcacacagcc ccagaggccg cccaggctct agccacactc   7080

tggcactgcc tgggacaggt gccctcagga acccaaatgc cactgccccc gtgaaagcca   7140

cttcaagcgt gttgcttcaa atcagaaggc atctacgcct gtggaagagg aggctgctgg   7200

gggcccaggt gtgcaggggg cagggccagg tgcaggggca cagcttatgc ctgtggccaa   7260

cccactgggg agcaaggctg gggatatgcc caggccagca gggccagcag gagtgactgc   7320

gccatcctga acacgtcctt gggcctccca ggaccttggt gcctcccatc tgggctggca   7380

caagcctcca gtcaaaagat gggtctctct ctcctgatag catggagcct ggatgtggga   7440

atggagccac accagcccca cgggagcccc acgacccatc gggctgtggg atgcatcccc   7500

acggccggga cccctcagcc tgtgacttgg tctgggcaga tgcaaaggcc accctgcagg   7560

gctgaggtgt ctgtggggaa ggaggtgccc agccctggga ggccatcttg ctcctgcttt   7620

ttatttaacc catggggctc tttggcctca ttttctgttt tttgagtttc tcgtgcactc   7680

caaactgtcc tggagccagc cctggtgtga aacagaggct tcctgctggc agaagaggcc   7740

caccgagtta cgtccacacc agctggccct gggcacctct ctctctggcc ttctgtccac   7800

actgggattt ggctctgatt tccagaaggc agggttagga aacacctgtt tccaggcaga   7860

gtaatgcttc tgtctgaatc aggcctcatg ggcttcacca gcagacacga aggtttcatt   7920

tagatggcga acacgtgttc tcatttctcc agggttctgg acccgtgagc tgaagcaggt   7980

gctgagaagt gggagaggcg gccactgggt ccctcagggt cactcacccc gccacgtgag   8040

gccacttccg cccagcactg ggggcgctgg gagctgaggg gcccacaggg gacgtgggag   8100

acagccccga tgcgtcccca tccgcagtga cgctagcgcg gagtcgtcgc caagcacgtg   8160

gagggacagc cctggagccc tggcctggcc cagcatctcc cagagtcact tcctgatgcc   8220

tccccagccc tgcccaggaa gggtttgtgg ccacagcccc acagcggccc cctcgcctcg   8280

accaccagtg cctccttcca agctgcctga gcaatcctgg gtggtgagct ccaccactcc   8340

cacccacgcc tcagcactgg gaccccccag ggatggtgtg gggattcctg ccccccgtcc   8400

atgcctcagc actgggagct gggaaggtgt gtgatttcct cccccacctc agtactggga   8460

cccccaggaa gggtgtgtgg ccccaccatc ctgaatgctc agggctggtg gtcagcgagg   8520

tggtttctaa accaagccct gggaggagcc atcctgggac tgtgcttgga caaggttggg   8580

gctcccgcag tgagctctag ccctccccag gaccctccca cggccccagg gtgccggcct   8640

tcagattgac cccattcgtg gatgagtcta caaggctccc cagtgcccag caagagtgtt   8700

tttacattca gaggtgagga aggggtgccg gcatctgccc cagacacaac cgggcaggta   8760

cagatgtcat ccccttgagg acagcaggga ggcgactcag gagaggctga tcagacggga   8820

gccgcatccc catcaccttc cagagagacc tcttcttttg ccaggtgtcg tgagggctgt   8880

ggcttagctg ggcctgcgtc catccccggt tctggggaga tgcccgggcc cctcctggat   8940

ggcagcagca gtggaggttt gggttttgag ggagccctaa gaacctgaga gacttagatg   9000

gagcatggca cgccctggag agtccacgtc cccagacccc tcatgccaac accattccac   9060

ccagcagttt cttccctgtg gtcagaacaa aacccccaag cctcaggcct caggctggtt   9120

ttctgacagg caaaatgctc cttacataag gaaagacctt tccttggctg accctaaagt   9180

agccaagggg agctcacatc gcctggcctg ccgccaccac caggctgcct gaccagctca   9240

ccgccttgtt ctagatgctt ctgaagcaac agctcgcctg gccccacccc catcaagcat   9300

ctgctgggca gcctccctcc ccggcccgcc tgtagctccc aaaggtctca agcctcaaca   9360

tcctggtaac caagtgcacc cagagggctg gcagggtcac atggaggcag gggacccttg   9420

gccccagggt ggtcgtcttc ccaggaggtc cgcctgtcag gtcagagggc agcaggaggc   9480

caccccacct ccccgggttc cctcgagcat tcctttgtca ggagcagctc ccccaggatc   9540

caggcatccc tggcccccct ttgcccccgc cctgctctca ggagccccct gccaggtgct   9600

ctgaccacag gaaacaggag ccctcagggc cactgccaga ggacggattc tgctgccaac   9660

cagaggtcct ggggctggcg gcgctggtgt gcctgccctg ggccttcagc agcccccata   9720

aggagaaagc tccagcctcc cgttcagaga aggctccatc ctggggacac gcctctccca   9780

aggtcaccca cgtgggggct ttgttactca tgcttcccag actgcgtgct gtgtcagagt   9840

tttcacacct gcctgatgtc ctgggggggc tcacagagga ccgaccctgc agggagatgc   9900

tgacccaccc tgagacccag gagaagaaaa cggccagggt ccaggctgct cccaccatcc   9960

ctgggggatt agcaccttgg ctgagcccga actgaccacc tggggcgtag gtccaagatt  10020

taattacaaa acgataggtg aatgtgggtt ctgtgtgcct gtgacataga gaatgttttc  10080

cacaccgcgt gtgaaatgac gagagctttt gtgtcacaca tgtagctgct acgagacaga  10140

cgctcttgtt ccggatcaga gcagcagaca gaaccggcac ttttagggtc caaaccctgt  10200

tgcccacaga acgcccatga caccagctgg gtggagctgc cgccgagtcc acgccccgtc  10260

tggctgggac ctggagctcc cctcaagctg cagatccact ctgcaccaca aggtggcctc  10320

gcagaggagc ctcccgagct ttggaaccag aggcaggctc agcgatgctc tccatccggc  10380

ctggccccac cgtgtgtatc aggtgtcaga ggccttgctg ggtgccaggc cacgtctgtg  10440

ctgtcacagc tttgaggggc cagcgggtcc tagggagagg cccgtgcgac gtgagtaaca  10500

gcagtttttc ttctgacagc tgggatggag gtgggtcctc cagggagtgc cccagtcctc  10560

gagagccaga cttgtgcacg ggcctggaaa tgaaggtctc aggcaggggc tgcgcacacc  10620

gatggtcagc attgccgttc ggggcctgca gtcgcccata atgggccctg ccccctaggc  10680

ctggcctctt ttgctttcct cctggatggt tcctctaccc ctggtccagc agggactcag  10740

cagtgcctgc cagctgcaga cccccatgct cctgcagcct ggaaccctcc tgccctccaa  10800

aggtcatggg gtgacccagg gtgggaacac cagaccccct caccccgtgt ccaccgccca  10860

tggccgggct cacagtgtct cagagccgtg gtgagccatc ctaggaccag tgtacctcac  10920

aacctttcag accagtgaag gccagtgggc tgggtggtcc aggcatgtcc ccaacgcagg  10980

tccagccatc tctgcacaga actggaatct cggttcattt cggtttcagc aggtcccatg  11040

tagttagcag gacagcactt gagttaggtc tgagaaagaa cgcctgtttg tcatggcatt  11100

tcctgtaagg agcccagagc cgtggcccca ggttgggacg gcggcgccag agctgggcct  11160

gagtctgacc caacctgtgc tgagtggtcc tgctggaatg ggaaccccaa gaggaccacc  11220

cctctctaaa agaagggaaa acagtaagcg agagggaggc tgcaggggcc cagaccttgg  11280

ctgaccttcc tagccatggt ctccaccctc cgagacccag gggccccgca gtgacagcag  11340

ggtgttgggc cacacagagc ccgagtaggt aaaggaaggt tctggaaacc acttttcaga  11400

acccaaaagg tgtctgggaa atggcgttac ctgccactgt tgttaagtgt ttactttgta  11460

tcaatactga attgttaaaa attttaatca taaaaaccaa tggaacatgt ttttcaaaaa  11520

aaaaaaaaa                                                          11529


<210>  609
<211>  2423
<212>  DNA
<213>  Human

<400>  609
ttccgcctcc agcgcgagcc ccgccgccgc cgagcatgga cgaccccgac tgcgactcca     60

cctgggagga ggacgaggag gatgcggagg acgcggagga cgaggactgc gaggacggcg    120

aggccgccgg cgcgagggac gcggacgcag gggacgagga cgaggagtcg gaggagccgc    180

gggcggcgcg gcccagctcg ttccagtcca gaatgacagg gtccagaaac tggcgagcca    240

cgagggacat gtgtaggtat cggcacaact atccggatct ggtggaacga gactgcaatg    300

gggacacgcc aaacctgagt ttctacagaa atgagatccg cttcctgccc aacggctgtt    360

tcattgagga cattcttcag aactggacgg acaactatga cctccttgag gacaatcact    420

cctacatcca gtggctgttt cctctgcgag aaccaggagt gaactggcat gccaagcccc    480

tcacgctcag ggaggtcgag gtgtttaaaa gctcccagga gatccaggag cggcttgtcc    540

gggcctacga gctcatgctg ggcttctacg ggatccggct ggaggaccga ggcacgggca    600

cggtgggccg agcacagaac taccagaagc gcttccagaa cctgaactgg cgcagccaca    660

acaacctccg catcacacgc atcctcaagt cgctgggtga gctgggcctc gagcacttcc    720

aggcgccgct ggtccgcttc ttcctggagg agacgctggt gcggcgggag ctgccggggg    780

tgcggcagag tgccctggac tacttcatgt tcgccgtgcg ctgccgacac cagcgccgcc    840

agctggtgca cttcgcctgg gagcacttcc ggccccgctg caagttcgtc tgggggcccc    900

aagacaagct gcggaggttc aagcccagct ctctgcccca tccgctcgag ggctccagga    960

aggtggagga ggaaggaagc cccggggacc ccgaccacga ggccagcacc cagggtcgga   1020

cctgtgggcc agagcatagc aagggtgggg gcagggtgga cgaggggccc cagccacgga   1080

gcgtggagcc ccaggatgcg ggacccctgg agaggagcca gggggatgag gcagggggcc   1140

acggggaaga taggccggag cccttaagcc ccaaagagag caagaagagg aagctggagc   1200

tgagccggcg ggagcagccg cccacagagc caggccctca gagtgcctca gaggtggaga   1260

agatcgctct gaatttggag gggtgtgccc tcagccaggg cagcctcagg acggggaccc   1320

aggaagtggg cggtcaggac cctggggagg cagtgcagcc ctgccgccaa cccctgggag   1380

ccagggtggc cgacaaggtg aggaagcgga ggaaggtgga tgagggtgct ggggacagtg   1440

ctgcggtggc cagtggtggt gcccagacct tggcccttgc cgggtcccct gccccatcgg   1500

ggcaccccaa ggctggacac agtgagaacg gggttgagga ggacacagaa ggtcgaacgg   1560

ggcccaaaga aggtacccct gggagcccat cggagacccc aggccccagc ccagcaggac   1620

ctgcagggga cgagccagcc gagagcccat cggagacccc aggcccccgc ccagcaggac   1680

ctgcagggga cgagccagcc gagagcccat cggagacccc aggcccccgc ccggcaggac   1740

ctgcagggga cgagccagcc gagagcccat cggagacccc aggccccagc ccggcaggac   1800

ctacaaggga tgagccagcc gagagcccat cggagacccc aggcccccgc ccggcaggac   1860

ctgcagggga cgagccagcc gagagcccat cggagacccc aggcccccgc ccggcaggac   1920

ctgcagggga cgagccagcc gagagcccat cggagacccc aggccccagc ccggcaggac   1980

ctacaaggga tgagccagcc aaggcggggg aggcagcaga gttgcaggac gcagaggtgg   2040

agtcttctgc caagtctggg aagccttaag gaaaggagtg cccgtcggcg tcttggtcct   2100

cctgtccctg ctgcaggggc tggggcctcc ggagctgctg cgggctcccc tcaggctctg   2160

cttcgtgacc cgtgacccat gacccacagt gctggcctcc tgtggggcca ctatagcagc   2220

caccagaagc cgcgaggccc tcagggaagc ccaaggcctg cagaagcctc ctggcctggc   2280

tgtgtcttcc ccacccagct ctcccctgcg cccctgtctt tgtaaattga cccttctgga   2340

gtggggggcg gcgggcaggg ctgcttttct tagtctgata ccaagcaagg ccttttctga   2400

ataaattcat ttgactttga aaa                                           2423


<210>  610
<211>  2793
<212>  DNA
<213>  Human

<400>  610
atggagatca gaggggcact cgatctgcga aaaaggcaag ttctaatatt ccttgttttg     60

ctgggattgt ctcgggcagg tactgaatct gcacactatt ctgtggcaga ggaaacagaa    120

attggctctt ttgtggctaa tctagcgagg gacctagggc tgggggtgga ggagctgtct    180

tcacgtgaag cccgggtagt gtctgatgat aataaaaagt atttgcacct tgatttgctg    240

actgggaatt tgctcctaaa tgagaaacta gaccgagacg agctgtgtgg ctccaccgag    300

ccctgtgtgc tgcattttca ggtggttttg gaaaaccctt tacagttttt tcggtttgag    360

ctgtgtgtca aagacataaa tgatcactcc cctacatttc tagacaagga aatacttatt    420

aaaatatcag aaggtaccac tgttggagct acctttctaa tggagagtgc tcaagatttg    480

gatgtcggaa gcaacagtct ccaaaactac acaattagcc ccaattctca cttctacatt    540

aaaattcccg acagtagtga cagaaagata tacccagagc tggtcctaga tagagcttta    600

gattatgaac aggaagctga actcagatta acactcacag cagtggatgg tggatccccg    660

cccaagtctg ggacaacttt ggttctcatc aaggtgttgg acatcaatga taatgcccct    720

gagtttcctc agagtctcta tgaggtgcaa gtccccgagg acagacccct tggctcctgg    780

attgccacca tctcagctaa ggatctggat gcaggaaact atggaaaaat atcttacaca    840

tttttccatg catcagaaga tattcgtaaa acatttgaaa ttaatccaat atctggggaa    900

gttaatttga gatcacccct ggattttgaa gtaatacagt cctacactat aaatattcag    960

gcaacagatg gtgggggtct ttcaggaaaa tgcacccttc tagttaaagt tatggatata   1020

aacgacaacc caccagaagt gaccatatcg tcgattacaa agagaattcc agagaatgcc   1080

tcagagaccc tagtagctct ttttagtatc ctagaccaag actctggaga caatgggagg   1140

atgatttgct ctattcaaga taacctccct tttttcctga aaccgacctt caagaacttt   1200

ttcactctag tttctgaaaa agcactggac agagagagcc aagccgagta caacatcacg   1260

atcaccgtca cagacttggg gacacccagg ctgaaaaccg agtacaacat aaccgtgctg   1320

ctctctgacg tcaatgacaa cgcccccacc ttcacccaaa cctcctacac cctgttcgtc   1380

cgcgagaaca acagccccgc cctgcacatc ggcagcgtca gcgccacaga cagagactca   1440

ggcaccaacg cccaggtcaa ctactcgctg ctgccgcccc aggaccggca cctgcccctc   1500

gcctccttgg tctccatcaa cgcggacaat ggccacctgt ttgccctcag gtcgctggac   1560

tacgaggccc tacaggagtt cgagtttcgc gtgggcgcca cagaccgcgg gtccccggcg   1620

ttgagcagcg aggcgctggt gcgcgtgctg gtgctggacg ccaacgacaa ctcgcccttc   1680

gtgctgtacc cgctgcagaa cggctccgcg ccctgcaccg agctggtgcc ccgggcggcc   1740

gagccgggct acctggtgac caaggtggtg gcggtggacg gcgactcggg ccagaacgcc   1800

tggctgtcgt accagctgct caaggccacg gagcccgggc tgttcggcgt gtgggcgcac   1860

aatggcgagg tgcgcaccgc caggctgctg agcgagcgcg acgcggccaa gcacaggctg   1920

gtggtgctgg tcaaggacaa tggcgagcct cctcgctcgg ccaccgccac gctgcacgtg   1980

ctcctggtgg acggcttctc ccagccctac ctgccgctcc ctgaggcggc cccggcccag   2040

gcccaggccg actccctcac cgtctacctg gtggtggcat tggcctcggt gtcgtcgctc   2100

ttcctcttct cggtgctcct gttcgtggcg gtgcggctgt gcaggaggag cagggcggcc   2160

tcggtgggtc gctgctcggt gcccgagggt ccctttccag ggcatctggt ggacgtgagc   2220

ggcaccggga ccctgtccca gagctaccaa tacgaggtgt gtctgacagg aggttccggg   2280

acaaatgagt tcaaatttct gaagccgatt atccccaatt ttcaagttca tgacactggt   2340

aggaatatgg gggaaatcga gaactttcga aatagctttg gacttaacat tcaataaaac   2400

aatttatttt aaatgtctaa tttttggtta ttcttggcaa gctgatggta ctttttgcat   2460

aatcttttgt ggattcttgg ttgtactgta gttgcatgca tgattatagc tcttgttttt   2520

ctcacagttt ctttaaaaat ctttattagt ggctataatg acgtggaaat gtaatctgtg   2580

ttttctggtt tttcatttat ttggccaaaa tgttatatta atggagttat tgctattttt   2640

gctgtgataa tggtattatg caagaccata ttctcaatta tttggatatg caaactaaag   2700

tattaagagc taatgtcatt atatatgtaa cttaaatcta gacaccatca aagcataaaa   2760

taaaaataaa aagcgttgct gaaaaaaaaa aaa                                2793


<210>  611
<211>  3060
<212>  DNA
<213>  Human

<400>  611
gccgggtttg ggggttggga cctccggctg caggtccgcc tgggccagac gcgcgagcgc     60

aagcagcggg ttagtggtcg cgcgcccgac ctccgcagtc ccagccgagc cgcgaccctt    120

ccggccgtcc ccaccccacc tcgccgccat gcgcctccgc cgcctagcgc tgttcccggg    180

tgtggcgctg cttcttgccg cggcccgcct cgccgctgcc tccgacgtgc tagaactcac    240

ggacgacaac ttcgagagtc gcatctccga cacgggctct gcgggcctca tgctcgtcga    300

gttcttcgcc ccctggtgtg gacactgcaa gagacttgca cctgagtatg aagctgcagc    360

taccagatta aaaggaatag tcccattagc aaaggttgat tgcactgcca acactaacac    420

ctgtaataaa tatggagtca gtggatatcc aaccctgaag atatttagag atggtgaaga    480

agcaggtgct tatgatggac ctaggactgc tgatggaatt gtcagccact tgaagaagca    540

ggcaggacca gcttcagtgc ctctcaggac tgaggaagaa tttaagaaat tcattagtga    600

taaagatgcc tctatagtag gttttttcga tgattcattc agtgaggctc actccgagtt    660

cctaaaagca gccagcaact tgagggataa ctaccgattt gcacatacga atgttgagtc    720

tctggtgaac gagtatgatg ataatggaga gggtatcatc ttatttcgtc cttcacatct    780

cactaacaag tttgaggaca agactgtggc atatacagag caaaaaatga ccagtggcaa    840

aattaaaaag tttatccagg aaaacatttt tggtatctgc cctcacatga cagaagacaa    900

taaagatttg atacagggca aggacttact tattgcttac tatgatgtgg actatgaaaa    960

gaacgctaaa ggttccaact actggagaaa cagggtaatg atggtggcaa agaaattcct   1020

ggatgctggg cacaaactca actttgctgt agctagccgc aaaaccttta gccatgaact   1080

ttctgatttt ggcttggaga gcactgctgg agagattcct gttgttgcta tcagaactgc   1140

taaaggagag aagtttgtca tgcaggagga gttctcgcgt gatgggaagg ctctggagag   1200

gttcctgcag gattactttg atggcaatct gaagagatac ctgaagtctg aacctatccc   1260

agagagcaat gatgggcctg tgaaggtagt ggtagcagag aattttgatg aaatagtgaa   1320

taatgaaaat aaagatgtgc tgattgaatt ttatgcccct tggtgtggtc actgtaagaa   1380

cctggagccc aagtataaag aacttggcga gaagctcagc aaagacccaa atatcgtcat   1440

agccaagatg gatgccacag ccaatgatgt gccttctcca tatgaagtca gaggttttcc   1500

taccatatac ttctctccag ccaacaagaa gctaaatcca aagaaatatg aaggtggccg   1560

tgaattaagt gattttatta gctatctaca aagagaagct acaaaccccc ctgtaattca   1620

agaagaaaaa cccaagaaga agaagaaggc acaggaggat ctctaaagca gtagccaaac   1680

accactttgt aaaaggactc ttccatcaga gatgggaaaa ccattgggga ggactaggac   1740

ccatatggga attattacct ctcagggccg agaggacaga atggatataa tctgaatcct   1800

gttaaatttt ctctaaactg tttcttagct gcactgttta tggaaatacc aggaccagtt   1860

tatgtttgtg gttttgggaa aaattatttg tgttggggga aatgttgtgg gggtggggtt   1920

gagttggggg tattttctaa ttttttttgt acatttggaa cagtgacaat aaatgagacc   1980

cctttaaact gtcttatttt ccaccagatt gagaaccaga tgttctctac acactatcac   2040

tgttcaatag agctttcttc agtgatggaa atgctctgta atctacactg ttcagtacag   2100

gtagctacgg agcatctgaa atatggctag aaactacatt tttgttttga ttaatttaaa   2160

tagccataca gttgctacca tactggtcac ggcagctgta gactgactgg gtccatagtt   2220

catcacctca aaattctttc aaaatttatt atctctttct ctccttacat gtttatttcc   2280

caggcctacc ctggtgatta gaacagctga agggcctttc ttgttaggct gtccatgccc   2340

taaggatggg ttcctgttta tccttgccac gcagctgagc ttactgcatg tttatatctc   2400

ccaaggactg ttctctgctc agaaatgccc tgtcaagggt gtggcatcac gcagtttcat   2460

ccaagttgtt tcaggaattg ctgacactgc tgggtgcagt tctatcccct aaagcctagg   2520

gtgtggccct ttaacttccc cttcagtaga actgggaaag gcagtaccat tcctagttat   2580

gagtgaagca tccactttct tttgtaacaa tgaggaacag aaaggataag actgaagagt   2640

gatcttttgt ccaactaaac catttatctc cttttgtagg taaattcaaa tcctgcccag   2700

ttatagtttt cagtcactgg agaattccag gtaggagccc tactttaggt gatcctagga   2760

actcctatgt tcagaaaaga attttcttcc tactatataa ttacagtatt tagctgtcaa   2820

ttttaagatg aatttggtag agccttatag taaagtatgt atcttggtca cacacaaagc   2880

ttggaaaaag taaaagatgt ctaaaccata atcttgtaac tcataacatc tgggctgggg   2940

cccggggatc taattgttta gagagcccca aaagtggctc agatgtaaag ccagggttaa   3000

gaaccatctg ccttggaaga tttaagggaa acatataaac ttgtacaaag gacaaaaaaa   3060


<210>  612
<211>  2200
<212>  DNA
<213>  Human

<400>  612
gcatcctctc accgccggaa gctgaactga ctcgtccgcg gccgctctac cccaacaggc     60

cgccaccagc gagagtgcgg ccataaccat cacgtgaccg cccaccgaca ccagcgagag    120

tgcagtcgta accgtcacgt gaccgcccac cgtcggcccg gcgctcccct ccgcccgaag    180

ctagcaagcg gcgcggccaa tgagaaaggc gcatgcctgg cccccgccgg cctgcagtct    240

agccgtagtg cgcctgcgcg cggctaggag gggccgtcag gcggggatac agcctggaag    300

gtaatgcatg tccatggtac acaaattcac aagtttggag accctgacac acccaccttc    360

tcacctgggc tctgcgtatc ccccagcctt gagggaagat gaagcctaaa ctgatgtacc    420

aggagctgaa ggtgcctgca gaggagcccg ccaatgagct gcccatgaat gagattgagg    480

cgtggaaggc tgcggaaaag aaagcccgct gggtcctgct ggtcctcatt ctggcggttg    540

tgggcttcgg agccctgatg actcagctgt ttctatggga atacggcgac ttgcatctct    600

ttgggcccaa ccagcgccca gccccctgct atgacccttg cgaagcagtg ctggtggaaa    660

gcattcctga gggcctggac ttccccaatg cctccacggg gaacccttcc accagccagg    720

cctggctggg cctgctcgcc ggtgcgcaca gcagcctgga catcgcctcc ttctactgga    780

ccctcaccaa caatgacacc cacacgcagg agccctctgc ccagcagggt gaggaggtcc    840

tccggcagct gcagaccctg gcaccaaagg gcgtgaacgt ccgcatcgct gtgagcaagc    900

ccagcgggcc ccagccacag gcggacctgc aggctctgct gcagagcggt gcccaggtcc    960

gcatggtgga catgcagaag ctgacccatg gcgtcctgca taccaagttc tgggtggtgg   1020

accagaccca cttctacctg ggcagtgcca acatggactg gcgttcactg acccaggtca   1080

aggagctggg cgtggtcatg tacaactgca gctgcctggc tcgagacctg accaagatct   1140

ttgaggccta ctggttcctg ggccaggcag gcagctccat cccatcaact tggccccggt   1200

tctatgacac ccgctacaac caagagacac caatggagat ctgcctcaat ggaacccctg   1260

ctctggccta cctggcgagt gcgcccccac ccctgtgtcc aagtggccgc actccagacc   1320

tgaaggctct actcaacgtg gtggacaatg cccggagttt catctacgtc gctgtcatga   1380

actacctgcc cactctggag ttctcccacc ctcacaggtt ctggcctgcc attgacgatg   1440

ggctgcggcg ggccacctac gagcgtggcg tcaaggtgcg cctgctcatc agctgctggg   1500

gacactcgga gccatccatg cgggccttcc tgctctctct ggctgccctg cgtgacaacc   1560

atacccactc tgacatccag gtgaaactct ttgtggtccc cgcggatgag gcccaggctc   1620

gaatcccata tgcccgtgtc aaccacaaca agtacatggt gactgaacgc gccacctaca   1680

tcggaacctc caactggtct ggcaactact tcacggagac ggcgggcacc tcgctgctgg   1740

tgacgcagaa tgggaggggc ggcctgcgga gccagctgga ggccattttc ctgagggact   1800

gggactcccc ttacagccat gaccttgaca cctcagctga cagcgtgggc aacgcctgcc   1860

gcctgctctg aggcccgatc cagtgggcag gccaaggcct gctgggcccc cgcggaccca   1920

ggtgctctgg gtcacggtcc ctgtccccgc gcccccgctt ctgtctgccc cattgtggct   1980

cctcaggctc tctcccctgc tctcccacct ctacctccac ccccaccggc ctgacgctgt   2040

ggccccggga cccagcagag ctgggggagg gatcagcccc caaagaaatg ggggtgcatg   2100

ctgggcctgg ccccctggcc cacccccact ttccagggca aaaagggccc agggttataa   2160

taagtaaata acttgtctgt aaaaaaaaaa aaaaaaaaaa                         2200


<210>  613
<211>  4128
<212>  DNA
<213>  Human

<400>  613
gtttccgggg cgcgccgcgg aacccggaag tggtcacgga actcggctgc ggctccatgg     60

tctgagttgt cagccgttgt tttttcgtgc tcgctagtcg ccgccgccgc tccgccatgg    120

ggaagcgaca gcaccaaaag gacaaaatgt acattacctg tgctgaatac actcactttt    180

atggtggcaa gaagccagat ctcccacaaa caaattttcg tcgtttacct tttgaccact    240

gcagtctctc tctgcagccc tttgtctacc cagtctgcac tcccgatggc atcgtctttg    300

acttactgaa cattgttcca tggcttaaga agtacgggac caaccccagc aatggagaga    360

agctggacgg gaggtccctg atcaagctga acttttccaa gaacagtgag gggaagtacc    420

actgcccagt gctgtttacc gtgttcacca acaacaccca catcgtggct gtgaggacga    480

ccggcaacgt ctacgcctat gaggcagtgg aacagctaaa tatcaaggcc aagaacttcc    540

gggacctgct gaccgacgag cccttctccc ggcaggacat catcaccctc caggacccca    600

ccaatttgga caagttcaat gtctctaact tctatcatgt gaagaataac atgaaaataa    660

tagacccaga tgaagagaag gccaaacagg acccgtctta ttatctgaaa aatacaaatg    720

ccgagacccg agagaccctg caggagctct acaaggagtt caaaggggac gagattctgg    780

cagccaccat gaaggccccg gagaagaaga aagtggacaa gctgaacgct gcccactatt    840

ccacagggaa ggtcagcgct tccttcacct ccaccgcgat ggtcccggag accacacatg    900

aagcagctgc catcgacgag gatgtgctgc gctaccagtt tgtgaagaag aagggctacg    960

tgcggctgca caccaacaag ggcgacctca acctggagct gcactgcgac ctgacaccaa   1020

aaacctgcga aaacttcatc aggctttgca agaagcatta ttacgatggc accatcttcc   1080

acagatccat ccggaacttt gtgatccaag ggggcgaccc cacaggcaca ggcacgggtg   1140

gggagtcata ctgggggaag cccttcaaag acgagttccg gcccaacctc tcgcacacgg   1200

gccgcggcat cctcagcatg gccaactccg ggcccaacag caacaggtct caattcttca   1260

tcacgtttcg ctcctgtgcc tacctggaca agaagcatac catctttgga cgggttgttg   1320

ggggctttga cgtactgaca gccatggaga atgtggagag tgaccccaaa actgaccgcc   1380

ctaaggagga gatccgcatt gatgccacta cagtgttcgt ggacccctat gaggaggccg   1440

atgcccagat tgcgcaggag cggaagacac agctcaaggt agccccggag accaaagtga   1500

agagcagcca gccccaggca gggagccagg gcccccagac cttccgccag ggcgtgggca   1560

agtacatcaa cccagcagcc acgaagcgag cagcagagga agagccctca accagtgcca   1620

ctgtccccat gtccaagaag aagcccagtc ggggttttgg ggacttcagc tcctggtagc   1680

agcaggttgg ccgctgtgga ccttggtggg gttgcagggc tgggggccca tgtccacatc   1740

tccatttcca gcctttctag cctgccctct gctgccagcc aataaattgc ttgcctgctg   1800

cctgcatccc ctttcctggc ccctgggagc ccacagcctt cccatccctt aacctgttgc   1860

caagggcctt ggccctgttt ccaggacctg gcccagccag agcccactgc tgggaccttc   1920

aagcacaagg cctgccctac acccaggctg gtgcctcagg cctctcctct agtaggcagg   1980

ccaggttagt gaggaaggac tgtgtctcca gattgtggtt tcctctttaa gacagggtct   2040

tgctctgttg cccaggctcc agtgcagtgg tgtgatcatg gctcactgca gcctcgacct   2100

cctgggctca agcaatcctc ctgcctcagc ctcgcaagta gctgggacta cagccgtgca   2160

ccactacatc cagctgtata tgtctggttt tcttacccct acttctgtca tcttctcagg   2220

gacagcctat ttatacaacc agtgtggtcc cctgaccaac gccattacct gggacaagtt   2280

ttcagacccc agacttactg agcctaagcc tctgcagggt gggcttctcg gtctgttttg   2340

acaaaacttc aggggcttct gaaggctggt gttggacggc agcattgagt ttcctgccgt   2400

gccctgcctg agctctcagg gccctgctca cctgctctgg ctgtgaacca cctgggcttc   2460

atctcaagcc tgcctggcgt ctctgtgccc ctgtgagaat cttgagggga cccacactgg   2520

gttgaggcca gtgtctcctg ctgtgagaac aagtggatgt ccctctcccc gccctcctgc   2580

tgaagtggcc ttgctgctct caggcccggc cactgggctc caagactctg ctcctcctgt   2640

cagtcactga ctctgatggc cttgggccgg ctgcatcagc agcccttaaa gaaagacccc   2700

tccctcaacc cccatttttc tgttaaatgt gcccctggct ggctttttct tcgtcttcag   2760

cccaggccag tggtcagtgt tctcatgtca tggactctcc ttgcctgaca cttgcctctt   2820

gggctccctg ttgccctcag gccacccccc acttctagtt cttcacacta agccctaact   2880

taggccttgt tcttggtttt ctcatttttg ttgccccaaa tcttgaacct gtcagcaact   2940

tgcaggctgt acctctgccc ttccttttct catcaatcac tgatgctgaa gctgcaggcc   3000

tgagcccttt gtctccctgg atgctgggtg gcgcctcatc tgcatctctg cctcacccca   3060

tccactgcca caggctgcct gatgaccact agaggtatgt ctgcccctcg tcaccctgct   3120

gcacaccaat ctgtggccct tcatcatgct aagaacaaga actgcgccat ggctggctcc   3180

ttctcttctc cagcccatcc ctctgcagcc tgtcatccct gtctgtgacc attggtcggg   3240

cccctgggct ctagagtgac ttttgacgcc ctccatccct cccgccaggc actgtcctcc   3300

gcaaggcctg gtgcagccct ggcagtaact ggcttgtaag aggctcagac accaagctgg   3360

gcctgcagag gaggggcaca gtaggacaca gtgactgccc aggtgtccac acacctgtag   3420

gcctctgagc cagcgtccag ggtacaggtg cgggtggtgg ggatgaaggc ctgaccaggg   3480

agggagaagc aggtttggag aggaccctgt gcccaccctg acagacaccc tggctggccc   3540

tgactgactg tattctctgg ccacattcaa gtcccccatt ggtgggggca gagaagtagg   3600

accaggccat ccttggctcc agagctcgaa gaccccaaga cagccctctg ctctcagcgg   3660

cgccacagag agcctgggct cagccttctg catcaggaca tggcctcgtc cactgagggc   3720

acgatttaaa catttgacat cagaagcttt atttgtaaac ctcacacaga taaggaccaa   3780

gggctggcgg tgtggccaga ggacagggga agctgaaggc cccgtgcttg agctcggcag   3840

tcctgctcct tgcagtgaag ccaccatggg tgaccgtcca gcctcacccg gtggcctgca   3900

cagtgaggga agggcttcag ggccatctgc tcccagggca ggggacaggc caccaaggac   3960

ctttggcaaa tgaaggttta catttctgta gtttgtttgt tttagagctt aatttgtagt   4020

tttttagcta ttaaaaccat ttgaattttt aacgacctga tgagggcatc aggtaaatta   4080

aaggattttg ggaagattct taaaaaaaaa aaaaaaaaaa aaaaaaaa                4128


<210>  614
<211>  1471
<212>  DNA
<213>  Human

<400>  614
ccgccggccg tgctgttccc gccaattcct gtggtaatcc ttaccgtggc gagttccgcg     60

ctcaatggag acgtttgacc ccaccgagct gcccgagctg cttaaacttt attaccggag    120

gctctttccc tactctcagt actatcgctg gctcaactac ggtggagtga taaagaatta    180

ctttcaacac cgtgaatttt cattcacatt gaaagatgat atttacattc gctaccaatc    240

cttcaacaac cagagtgatc tggaaaagga gatgcagaaa atgaatccat acaagattga    300

tataggcgca gtatattctc acagacccaa tcaacacaat acagtgaagc tgggagcttt    360

ccaggctcag gaaaaagaac tggtatttga cattgacatg acagactatg acgatgtgag    420

gagatgttgt agttctgcag acatatgtcc taagtgctgg accctcatga caatggccat    480

acgcatcatt gacagagcat tgaaggagga ctttggattt aagcatcgtc tctgggtata    540

ttctggaagg agaggtgttc attgttgggt ctgtgatgaa tcagttagaa aactgtcttc    600

tgcagtacgt tctgggatag ttgagtattt gagccttgta aagggtggtc aagacgttaa    660

aaagaaagtt cacctaagtg aaaaaattca cccttttatc agaaaatcta taaacataat    720

aaaaaaatac tttgaagaat atgccttggt taatcaagat attctcgaaa ataaagaaag    780

ctgggataag attttagccc ttgttcctga aacaattcat gatgaacttc aacaaagctt    840

ccaaaagtct cacaattcac ttcagcgttg ggagcacttg aagaaagtag ccagcagata    900

tcagaataac atcaaaaatg acaaatatgg accctggctg gagtgggaga ttatgctcca    960

gtactgtttt ccacggctgg atatcaatgt cagcaaagga atcaatcatc tactgaagag   1020

cccttttagt gttcatccta aaacaggtcg catatctgtg cctattgatt tgcagaaagt   1080

ggaccagttt gatccattta ctgttccgac cataagcttc atctgccgtg aattggatgc   1140

catttccact aatgaagagg aaaaagagga gaatgaagct gaatctgatg tcaaacatag   1200

aaccagagat tataagaaga ccagtctagc accttatgtg aaagtttttg aacattttct   1260

tgaaaatctg gataaatccc gaaaaggaga acttcttaag aagagtgatt tacaaaaaga   1320

tttctgaaga cagagctcct caaaccattg tggatatctt ctgccttcaa ccacagatca   1380

aatacttcaa gagccattta ataaatatgg cagaactata tatgtgtctt aaacctcaaa   1440

gtaaattttc cttgagaaat aaaaaaaaaa a                                  1471


<210>  615
<211>  1281
<212>  DNA
<213>  Human

<400>  615
gatatctctg gaatagactg cgctaccctg cgccgccgcc gtcaaactcc cgcagacttc     60

tctgtagatc gctgagcgat actttcggca gcacctcctt gattctcagt tttgctggag    120

gccgcaacca ggcccgcgcc gccaccatgt ttcgaaatca gtatgacaat gatgtcactg    180

tttggagccc ccagggcagg attcatcaaa ttgaatatgc aatggaagct gttaaacaag    240

gttcagccac agttggtctg aaatcaaaaa ctcatgcagt tttggttgca ttgaaaaggg    300

cgcaatcaga gcttgcagct catcagaaaa aaattctcca tgttgacaac catattggta    360

tctcaattgc ggggcttact gctgatgcta gactgttatg taattttatg cgtcaggagt    420

gtttggattc cagatttgta ttcgatagac cactgcctgt gtctcgtctt gtatctctaa    480

ttggaagcaa gacccagata ccaacacaac gatatggccg gagaccatat ggtgttggtc    540

tccttattgc tggttatgat gatatgggcc ctcacatttt ccaaacctgt ccatctgcta    600

actattttga ctgcagagcc atgtccattg gagcccgttc ccaatcagct cgtacttact    660

tggagagaca tatgtctgaa tttatggagt gtaatttaaa tgaactagtt aaacatggtc    720

tgcgtgcctt aagagagacg cttcctgcag aacaggacct gactacaaag aatgtttcca    780

ttggaattgt tggtaaagac ttggagttta caatctatga tgatgatgat gtgtctccat    840

tcctggaagg tcttgaagaa agaccacaga gaaaggcaca gcctgctcaa cctgctgatg    900

aacctgcaga aaaggctgat gaaccaatgg aacattaagt gataagccag tctatatatg    960

tattatcaaa tatgtaagaa tacaggcacc acatactgat gacaataatc tatactttga   1020

accaaaagtt gcagagtggt ggaatgctat gttttaggaa tcagtccaga tgtgagtttt   1080

ttccaagcaa cctcactgaa acctatataa tggaatacat ttttctttga aagggtctgt   1140

ataatcattt tctagaaagt atgggtatct atactaatgt ttttatatga agaacatagg   1200

tgtctttgtg gttttaaaga caactgtgaa ataaaattgt ttcaccgcct ggtaaaaaaa   1260

aaaaaaaaaa aaaaaaaaaa a                                             1281


<210>  616
<211>  6018
<212>  DNA
<213>  Human

<400>  616
cctcgcgccg cccgcccggc agcccggccg gcgcgcgcac gccgcgagcc gctggcgctc     60

gggctccgct cggatcccat gcaacagcca cgatgtgaag cggggcagag ccgggggagc    120

ccagcccagc cagcctccag acgttgcccc atctgacgct cggctcgagg cctctctgtg    180

agggaccggg gggccatccc cctccagggc ggagatcgga ggtcgctgcc aagcatggcg    240

cccacctggg gccctggcat ggtgtctgtg gttggtccca tgggcctcct tgtggtcctg    300

ctcgttggag gctgtgcagc agaagagccc cccaggttta tcaaagaacc caaggaccag    360

atcggcgtgt cggggggtgt ggcctctttc gtgtgtcagg ccacgggtga ccccaagcca    420

cgagtgacct ggaacaagaa gggcaagaag gtcaactctc agcgctttga gacgattgag    480

tttgatgaga gtgcaggggc agtgctgagg atccagccgc tgaggacacc gcgggatgaa    540

aacgtgtacg agtgtgtggc ccagaactcg gttggggaga tcacagtcca tgccaagctt    600

actgtcctcc gagaggacca gctgccctct ggcttcccca acatcgacat gggcccacag    660

ttgaaggtgg tggagcggac acggacagcc accatgctct gtgcagccag cggcaaccct    720

gaccctgaga tcacctggtt caaggacttc ctgcctgtgg atcctagtgc cagcaatgga    780

cgcatcaaac agctgcgatc aggagccctg cagattgaaa gcagtgagga aaccgaccag    840

ggcaaatatg agtgtgtggc caccaacagc gccggcgtgc gctactcctc acctgccaac    900

ctctacgtgc gagagcttcg agaagtccgc cgcgtggccc cgcgcttctc catcctgccc    960

atgagccacg agatcatgcc agggggcaac gtgaacatca cctgcgtggc cgtgggctcg   1020

cccatgccat acgtgaagtg gatgcagggg gccgaggacc tgacccccga ggatgacatg   1080

cccgtgggtc ggaacgtgct ggaactcaca gatgtcaagg actcggccaa ctacacctgc   1140

gtggccatgt ccagcctggg cgtcattgag gcggttgctc agatcacggt gaaatctctc   1200

cccaaagctc ccgggactcc catggtgact gagaacacag ccaccagcat caccatcacg   1260

tgggactcgg gcaacccaga tcctgtgtcc tattacgtca tcgaatataa atccaagagc   1320

caagacgggc cgtatcagat taaagaggac atcaccacca cacgttacag catcggcggc   1380

ctgagcccca actcggagta cgagatctgg gtgtcggccg tcaactccat cggccagggg   1440

ccccccagcg agtccgtggt cacccgcaca ggcgagcagg ccccggccag cgcgccgcgg   1500

aacgtgcaag cccggatgct cagcgcgacc accatgattg tgcagtggga ggagccggtg   1560

gagcccaacg gcctgatccg cggctaccgc gtctactaca ccatggaacc ggagcacccc   1620

gtgggcaact ggcagaagca caacgtggac gacagcctgc tgaccaccgt gggcagcctg   1680

ctggaggacg agacctacac cgtgcgggtg ctcgccttca cctccgtcgg cgacgggccc   1740

ctctcggacc ccatccaggt caagacgcag cagggagtgc cgggccagcc catgaacctg   1800

cgggccgagg ccaggtcgga gaccagcatc acgctgtcct ggagcccccc gcggcaggag   1860

agtatcatca agtacgagct cctcttccgg gaaggcgacc atggccggga ggtgggaagg   1920

accttcgacc cgacgacttc ctacgtggtg gaggacctga agcccaacac ggagtacgcc   1980

ttccgcctgg cggcccgctc gccgcagggc ctgggcgcct tcacccccgt ggtgcggcag   2040

cgcacgctgc agtccatctc gcccaagaac ttcaaggtga aaatgatcat gaagacatca   2100

gttctgctca gctgggagtt ccctgacaac tacaactcac ccacacccta caagatccag   2160

tacaatgggc tcacactgga tgtggatggc cgtaccacca agaagctcat cacgcacctc   2220

aagccccaca ccttctacaa ctttgtgctg accaatcgcg gcagcagcct gggcggcctc   2280

cagcagacgg tcaccgcctg gactgccttc aacctgctca acggcaagcc cagcgtcgcc   2340

cccaagcctg atgctgacgg cttcatcatg gtgtatcttc ctgacggcca gagccccgtg   2400

cctgtccaga gctatttcat tgtgatggtg ccactgcgca agtctcgtgg aggccaattc   2460

ctgaccccgc tgggtagccc agaggacatg gatctggaag agctcatcca ggacatctca   2520

cggctacaga ggcgcagcct gcggcactcg cgtcagctgg aggtgccccg gccctatatt   2580

gcagctcgct tctctgtgct gccacccacg ttccatcccg gcgaccagaa gcagtatggc   2640

ggcttcgata accggggcct ggagcccggc caccgctatg tcctcttcgt gcttgccgtg   2700

cttcagaaga gcgagcctac ctttgcagcc agtcccttct cagacccctt ccagctggat   2760

aacccggacc cccagcccat cgtggatggc gaggaggggc ttatctgggt gatcgggcct   2820

gtgctggccg tggtcttcat aatctgcatt gtcattgcta tcctgctcta caagaacaaa   2880

cccgacagta aacgcaagga ctcagaaccc cgcaccaaat gcctcctgaa caatgccgac   2940

ctcgcccctc accaccccaa ggaccctgtg gaaatgagac gcattaactt ccagactcca   3000

ggcatgctta gccacccgcc aattcccatc gcagacatgg cggagcacac ggagcggctc   3060

aaggccaacg acagcctcaa gctctcccag gagtatgagt ccatcgaccc tggacagcag   3120

ttcacatggg aacattccaa cctggaagtg aacaagccga agaaccgcta tgccaacgtc   3180

atcgcctatg accactcccg tgtcatcctc cagcccattg aaggcatcat gggcagtgat   3240

tacatcaatg ccaactacgt ggacggctac cggtgtcaga acgcgtacat tgccacgcag   3300

gggccgctgc ctgagacctt tggggacttc tggcgtatgg tgtgggagca gcggtcggcg   3360

accatcgtca tgatgacgcg gctggaggag aagtcacgga tcaagtgtga tcagtattgg   3420

cccaacagag gcacggagac ctacggcttc atccaggtca cgttgctaga taccatcgag   3480

ctggccacat tctgcgtcag gacattctct ctgcacaaga atggctccag tgagaaacgc   3540

gaggtccgcc agttccagtt tacggcgtgg ccggaccatg gcgtgcccga atacccaacg   3600

cccttcctgg ctttcctgcg gagagtcaag acctgcaacc cgccagatgc cggccccatc   3660

gtggttcact gcagtgccgg tgtgggccgc acaggctgct ttatcgtcat cgacgccatg   3720

cttgagcgga tcaagccaga gaagacagtc gatgtctatg gccacgtgac gctcatgagg   3780

tcccagcgca actacatggt gcagacggag gaccagtaca gcttcatcca cgaggccctg   3840

ctggaggccg tgggctgtgg caacacagaa gtgcccgcac gcagcctcta tgcctacatc   3900

cagaagctgg cccaggtgga gcctggcgaa cacgtcactg gcatggaact cgagttcaag   3960

cggctggcta actccaaggc ccacacgtca cgcttcatca gtgccaatct gccttgtaac   4020

aagttcaaga accgcctggt gaacatcatg ccctatgaga gcacacgggt ctgtctgcaa   4080

cccatccggg gtgtggaggg ctctgactac atcaacgcca gcttcattga tggctacagg   4140

cagcagaagg cctacatcgc gacacagggg ccgctggcgg agaccacgga agacttctgg   4200

cgcatgctgt gggagaacaa ttcgacgatc gtggtgatgc tgaccaagct gcgggagatg   4260

ggccgggaga agtgtcacca gtactggccg gccgagcgct ctgcccgcta ccagtacttt   4320

gtggtagatc cgatggcaga atacaacatg cctcagtata tcctgcgaga gttcaaggtc   4380

acagatgccc gggatggcca gtcccggact gtccggcagt tccagttcac agactggccg   4440

gaacagggtg tgccaaagtc gggggagggc ttcatcgact tcattggcca agtgcataag   4500

actaaggagc agtttggcca ggacggcccc atctctgtcc actgcagtgc cggcgtgggc   4560

aggacgggcg tcttcatcac gcttagcatc gtgctggagc ggatgcggta tgaaggcgtg   4620

gtggacatct ttcagacggt gaagatgcta cgaacccagc ggccggccat ggtgcagaca   4680

gaggatgagt accagttctg ttaccaggcg gcactggagt acctcggaag ctttgaccac   4740

tatgcaacct aaagccatgg ttccccccag gcccgacacc actggccccg gatgcctctg   4800

cccctcccgg gcggacctcc tgaggcctgg acccccagtg ggcagggcag gaggtggcag   4860

cggcagcagc tgtgtttctg caccatttcc gaggacgacg cagcccctcg agccccccca   4920

ccggccccgg ccgccccagc gacctccctg gcaccggccg ccgccttcaa atacttggca   4980

cattcctcct ttccttccaa ttccaaaacc agattccggg gtggggggtg gggggatggt   5040

gagcaaatag gagtgctccc cagaaccaga ggagggtggg gcacagacca tagacggacc   5100

cctcgtcctc ccccagcggt ggtaggggga cccggggggc tcctccccgc tctgcagcct   5160

ggggacactg ggctgggacc agaatccagc tttcttttaa aactctcagt gtaactgtat   5220

cccgtgacat ttcatttttt ttaaatagtg tatttttttt tccatttttt tttttaagag   5280

aaacaaacaa aagactcgcc agtcaatgac tttcaaagag aactaacttt ggcttattca   5340

tattctgttc aaagacagtc tattttttca ctgtagaaag cgtccttgtg tgatagttac   5400

gttcgcaaac gcgcacgcca ggcccatggc tgtaccttgg cttttttttt tttttttttt   5460

tttttaattt ttcctaccat cagaaagtgt gctttgctca cagaagaatg ggatgtcctt   5520

ttttctttct tggctttttt tttccccctt tttgtttcat ttttataaat taaattttca   5580

gacatatcaa atacagttct gagggtaagg tcatggggga gctcggaccc agtggcgttg   5640

ggtgcggttg agggggacgc tgctgtaaga ggagagagat gacagtggtc ctcctctgag   5700

agcctgagct gtctccccgt ctcccgcccc caaggagaca gagaggatcc tacttcttcg   5760

gggacagtgg ctgtatggct gtgctgcccc acatcaggga ccctttcccc ctgggactgt   5820

ggggcagttt gggagcaaaa ccagaaggac aggcccccct ctacccgcct accctgagca   5880

agcgagttgt tcctctttgt acaagggcag gtctgcggtt actttcaaca ctgtttattc   5940

cagcggaagc agccgggtgg ttttcccacc cccgtgtatg tagatatatc gactttgtat   6000

taaaggaaga tcgtctga                                                 6018


<210>  617
<211>  1352
<212>  DNA
<213>  Human

<400>  617
ggcccacgtg gttccgacag tcaagatggc gggagcagct acccaggctt ccctggagtc     60

ggccccacgg atcatgcggc tggtggccga atgcagccgc tccagggccc gggcaggcga    120

gctgtggctg ccgcatggga cagtggccac tcctgtgttc atgccagtgg gcacgcaggc    180

caccatgaag ggcatcacga ccgaacagct ggacgctctg ggttgccgca tctgcctggg    240

caatacctac catctgggtc taaggccggg acccgagctg atccagaaag ccaacggtct    300

ccacggcttc atgaattggc ctcataatct gctaacggac agcggcggtt tccagatggt    360

gtcgctggtg tctctgtccg aggtgacgga ggagggcgtc cgcttccgct ccccctacga    420

cggcaatgag accctgctga gcccggagaa atccgtgcag atccagaatg cgctgggctc    480

ggacatcatc atgcagctgg acgacgtggt tagcagtact gtgactgggc cacgtgtgga    540

ggaggccatg tacaggtcaa tccgctggct ggaccggtgc attgcagccc atcagcggcc    600

ggacaagcag aacctcttcg ccattatcca gggtgggctg gacgcagatc tccgggccac    660

ctgccttgaa gagatgacca agcgagacgt gcctggcttc gccatcgggg gcctgagcgg    720

gggtgagagc aagtcgcagt tctggcggat ggtggcgctg agcacctctc ggctgccgaa    780

ggacaagccc cgatatctga tgggggttgg ctatgccact gatctggtag tctgcgtggc    840

tcttggatgt gacatgttcg actgcgtctt ccccacacgg acagcgcgct ttggctctgc    900

cctggtgccc actgggaacc tgcagttgag gaagaaggtg tttgagaagg acttcggccc    960

catagacccg gagtgcacct gccccacgtg ccaaaagcac agccgcgcct tcctgcacgc   1020

actgctgcac agtgacaaca cggccgcgct gcaccacctc acggtccaca acatcgccta   1080

ccagctgcag ctcatgagcg ccgtccgcac cagcatcgtg gagaagcgct tcccggactt   1140

cgtgcgggac ttcatgggcg ccatgtacgg ggatcccacc ctctgtccca cctgggccac   1200

tgacgctctg gcctctgtgg gaatcacact gggctgacct ggcattggga gagggaggga   1260

ggaaggaagg gagggagggg ctggaagata ctgaaggatt cctttttgaa aggttttttt   1320

tattgtaact tacaaaaaaa aaaaaaaaaa aa                                 1352


<210>  618
<211>  704
<212>  DNA
<213>  Human

<400>  618
ggtttatagg tcccggcccg agcctccggc cgcccgccgg gtttgtcccg cgatccccga     60

ccatgcccgc cgacctcagc ggtacttgga ccctgctcag cagcgacaac ttcgagggct    120

acatgctggc cctaggtatt gactttgcca ctcgtaaaat agccaagttg ctgaagccac    180

agaaagtgat tgagcagaat ggggattctt ttaccatcca cacgaacagc agcctaagga    240

actactttgt gaaatttaaa gttggagaag aatttgatga agataacaga ggcctggaca    300

acagaaaatg caagagtttg gttatctggg acaatgacag gctcacctgt atccagaagg    360

gagaaaagaa gaacagaggc tggacccatt ggatcgaagg agacaaactc cacctggaaa    420

tgttctgtga aggtcaagtg tgcaaacaga cattccagag agcctgatcc acatccagca    480

gcagagccca cttgtggctg cagctttatg ccaaattata ttgcagactg aacagacgtt    540

tatctatccc atttggcgac gaggactcgt ggctggagag agccacacag cgtgtaacct    600

gaagtcatct agattatggg gaaactgctc agcttcaata aacctgtcca aatgaaaaaa    660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa                     704


<210>  619
<211>  1593
<212>  DNA
<213>  Human

<400>  619
agctgtaggg gaggcgctgc gcccccggcc ccagccgatc gggggctcct ggcgctagcc     60

tccctccaga gcgccgcagg agtccctcct gccgtctgac ttgagtccct gctgctgcag    120

tgcacgcccc ttcggcagcc agggtggggc ccagacccaa cctggcccct cctgccccca    180

ccccgccttt gggtcgctga cccccaggct gtggtgaggg tctgagagct ggtaccacgg    240

agcctgggca acctcctccg cccacccatg cccaccccgc atgaggctga gaagcagatc    300

acagggccag aggaggcgga ccggccccct tcaatgtcca gtcatgatac agcctctcca    360

gcggccccca gccgcaaccc ctgctgcctg tgctggtgct gctgctgtag ctgctcctgg    420

aaccaagagc ggcggcgcgc gtggcaggcc tcccgggaga gcaagctgca gcccctcccc    480

agctgtgaag tatgtgccac gccaagtcct gaggaggtgc agagctgggc gcagtctttt    540

gacaagctga tgcacagccc agcgggacgc agcgtgttcc gggcgttcct gcggacagag    600

tacagcgagg agaacatgct cttctggttg gcctgcgagg agctgaaggc cgaggccaac    660

cagcatgtgg tagacgagaa ggcgaggctc atctacgagg actacgtatc catcctgtcc    720

cccaaggagg tgagcctgga ctcccgtgtg cgggagggca tcaacaagaa gatgcaggag    780

ccgtccgcac acacgttcga cgacgcgcag ctgcagatct acacgctcat gcaccgggac    840

tcctaccccc gcttcctcag ctctcccacc taccgtgccc tgctgctgca ggggccatca    900

cagtcctcct ccgaggccta ggccgccccc agcagcacag accccgccgc ctcctacggc    960

cgactctggg ttcccttcag gtgttgttgt cggcagggct gtcagggcac atgcctggcc   1020

ggctggggtc cccacccgcg gagacggtcc tagacccagt ggggagtgct gtgtctcctg   1080

ggtctgccca cccgtggcca agcaggaact ccaggtgcag ggcgggcctc caggtgcagg   1140

gcgggccaga agccccctca tcggcccgca gctggctggc ccagtgctcc tggctggggg   1200

ctcttgcgtg gtgagagtag gggtcccccc aggagccatg ctggacccat gagcctcgct   1260

ggggcctcct ccccaggcag ccaatgggcc ccagacaagc ctttggtggg gaacagaacc   1320

tccgcatcgt gtagttttgt gacataagga gacctcctac ttgagctgtc tgtaccccag   1380

aatcaaacac agaacctcag aaccagattt aggacctcag aatcctgcac tcaaggtggc   1440

aggacccaat ttctgtttta tatgttcatg aactttaaac ctggaaacat gtccttacta   1500

ggtgttttat caaaaaaaag ttttcatatt tatctctatc cctaaccccc caaaaatagg   1560

atgtcttatt attgaagata tttttaaagc aaa                                1593


<210>  620
<211>  2327
<212>  DNA
<213>  Human

<400>  620
gcgcggggcg gggcttccgg gcggggcagg ctggcttccg gcgggagcgg ggccgcggat     60

ggccgtatac agggcagcgc tcggggcttc gctcgcggct gcccgactct tgcccctcgg    120

tcgctgttcc ccgtcgccgg cgccccgctc tacgttgtcg ggcgccgcca tggagcccgc    180

gcctcgctgg ctggcggggc tgcgcttcga caaccgcgcc ctgcgcgccc tgcccgtgga    240

ggcgccgccg cccggtcccg agggcgcccc gtccgcgccg cggcccgtgc ccggggcctg    300

cttcacccgc gtgcagccca ccccgctgcg gcagccgcgc ctcgtggcgc tgtcagagcc    360

cgcgctggcg ttgctgggcc tgggcgcgcc gcccgcgcgc gaggccgagg ccgaggccgc    420

gctgttcttc agcggcaacg cgctcctgcc gggcgccgag cccgccgcgc actgctactg    480

cggccaccaa ttcggccagt tcgccgggca gctgggcgac ggcgccgcca tgtacctggg    540

cgaggtgtgc acggcgaccg gcgagcgctg ggagctgcag ctcaagggcg ccgggcccac    600

gcccttctcc agacaggccg acggtcgcaa ggtcctacgg tcaagcatcc gggagtttct    660

atgcagcgaa gccatgttcc acctgggagt ccccaccaca cgggccggcg cctgcgtcac    720

gtccgagtcc acggtggtgc gcgacgtgtt ctatgatggt aatcccaaat atgaacaatg    780

cacggttgtg ttgcgtgtag cttccacttt cataaggttt ggatcctttg agatttttaa    840

gtctgcagat gagcacacag ggcgtgcagg ccccagcgtg gggaggaacg acattcgagt    900

gcagctgctc gactatgtca tcagctcctt ttaccccgag atccaggctg ctcatgccag    960

cgacagcgtg cagagaaatg ctgccttctt ccgggaggtg acgcggcgca cggcgcggat   1020

ggtggccgag tggcagtgtg tgggcttctg ccacggcgtg ctcaacaccg acaacatgag   1080

catcctgggg ctcaccatcg actacgggcc ctttggcttc ctggacaggt acgaccccga   1140

ccacgtgtgc aatgcctccg acaacaccgg ccgctacgcg tacagcaagc agcccgaggt   1200

gtgcaggtgg aacctgcgga agctggccga ggccctgcag ccggaactgc ccctggagct   1260

gggggaggcc atcctggccg aggagtttga cgccgagttc caaaggcact acctgcagaa   1320

gatgcgcagg aagctgggcc tcgtgcaggt ggagctggag gaagacgggg cgctggtgtc   1380

caagctcctg gagaccatgc atctgaccgg tgccgacttc acaaacacct tctacttgct   1440

gagctccttc ccagtggagc tagagtcgcc aggcctggcg gaattcctgg ccaggctgat   1500

ggagcagtgt gcctccctgg aggagctgag gctggccttc cggccccaga tggatccccg   1560

gcagctatcc atgatgctga tgctggcgca gtcaaacccg cagctgttcg cgcttatggg   1620

cacccgggca ggcatcgcca gggagctgga gcgtgtggag cagcagtctc ggctggagca   1680

gctgagtgcg gcagagctgc agagcaggaa ccagggccac tgggctgact ggctacaggc   1740

gtacagagcc cggctggaca aggacctgga aggcgctggg gacgctgccg cctggcaggc   1800

tgagcacgtg cgcgtgatgc acgccaacaa cccgaagtac gtgctgagga actacatcgc   1860

gcagaatgcc atcgaggctg ccgagcgcgg ggacttctca gaggtgcggc gggtgctgaa   1920

actactggag accccttacc actgcgaggc gggggccgcc acagacgccg aggccacgga   1980

agccgacggg gcggacggca ggcagcgctc ctacagcagt aagcccccgc tctgggcagc   2040

agaactgtgc gtgacatgat cttcgtaacg gcctcggcac gctccacacc cctggagtct   2100

cccgaggccc ccatgtgctg ctgagtggcc aagatgatgc caggctgccc tatacactgg   2160

gggattctgc cctggcccat gcacacccgt ctttccatga tggcagagac atccagtcag   2220

gacctgaccc gtctctgtct gaggccggct cagcagtgca gcctggtccc tgggggctgg   2280

acccaggctc ctaaataaac cagcaactcc ctcgaaaaaa aaaaaaa                 2327


<210>  621
<211>  2405
<212>  DNA
<213>  Human

<400>  621
tccggcgtgg tgcgcaggcg cggtatcccc cctcccccgc cagctcgacc ccggtgtggt     60

gcgcaggcgc agtctgcgca gggactggcg ggactgcgcg gcggcaacag cagacatgtc    120

gggggtccgg ggcctgtcgc ggctgctgag cgctcggcgc ctggcgctgg ccaaggcgtg    180

gccaacagtg ttgcaaacag gaacccgagg ttttcacttc actgttgatg ggaacaagag    240

ggcatctgct aaagtttcag attccatttc tgctcagtat ccagtagtgg atcatgaatt    300

tgatgcagtg gtggtaggcg ctggaggggc aggcttgcga gctgcatttg gcctttctga    360

ggcagggttt aatacagcat gtgttaccaa gctgtttcct accaggtcac acactgttgc    420

agcacaggga ggaatcaatg ctgctctggg gaacatggag gaggacaact ggaggtggca    480

tttctacgac accgtgaagg gctccgactg gctgggggac caggatgcca tccactacat    540

gacggagcag gcccccgccg ccgtggtcga gctagaaaat tatggcatgc cgtttagcag    600

aactgaagat gggaagattt atcagcgtgc atttggtgga cagagcctca agtttggaaa    660

gggcgggcag gcccatcggt gctgctgtgt ggctgatcgg actggccact cgctattgca    720

caccttatat ggaaggtctc tgcgatatga taccagctat tttgtggagt attttgcctt    780

ggatctcctg atggagaatg gggagtgccg tggtgtcatc gcactgtgca tagaggacgg    840

gtccatccat cgcataagag caaagaacac tgttgttgcc acaggaggct acgggcgcac    900

ctacttcagc tgcacgtctg cccacaccag cactggcgac ggcacggcca tgatcaccag    960

ggcaggcctt ccttgccagg acctagagtt tgttcagttc caccctacag gcatatatgg   1020

tgctggttgt ctcattacgg aaggatgtcg tggagaggga ggcattctca ttaacagtca   1080

aggcgaaagg tttatggagc gatacgcccc tgtcgcgaag gacctggcgt ctagagatgt   1140

ggtgtctcgg tccatgactc tggagatccg agaaggaaga ggctgtggcc ctgagaaaga   1200

tcacgtctac ctgcagctgc accacctacc tccagagcag ctggccacgc gcctgcctgg   1260

catttcagag acagccatga tcttcgctgg cgtggacgtc acgaaggagc cgatccctgt   1320

cctccccacc gtgcattata acatgggcgg cattcccacc aactacaagg ggcaggtcct   1380

gaggcacgtg aatggccagg atcagattgt gcccggcctg tacgcctgtg gggaggccgc   1440

ctgtgcctcg gtacatggtg ccaaccgcct cggggcaaac tcgctcttgg acctggttgt   1500

ctttggtcgg gcatgtgccc tgagcatcga agagtcatgc aggcctggag ataaagtccc   1560

tccaattaaa ccaaacgctg gggaagaatc tgtcatgaat cttgacaaat tgagatttgc   1620

tgatggaagc ataagaacat cggaactgcg actcagcatg cagaagtcaa tgcaaaatca   1680

tgctgccgtg ttccgtgtgg gaagcgtgtt gcaagaaggt tgtgggaaaa tcagcaagct   1740

ctatggagac ctaaagcacc tgaagacgtt cgaccgggga atggtctgga acacggacct   1800

ggtggagacc ctggagctgc agaacctgat gctgtgtgcg ctgcagacca tctacggagc   1860

agaggcacgg aaggagtcac ggggcgcgca tgccagggaa gactacaagg tgcggattga   1920

tgagtacgat tactccaagc ccatccaggg gcaacagaag aagccctttg aggagcactg   1980

gaggaagcac accctgtcct atgtggacgt tggcactggg aaggtcactc tggaatatag   2040

acccgtgatc gacaaaactt tgaacgaggc tgactgtgcc accgtcccgc cagccattcg   2100

ctcctactga tgagacaaga tgtggtgatg acagaatcag cttttgtaat tatgtataat   2160

agctcatgca tgtgtccatg tcataactgt cttcatacgc ttctgcactc tggggaagaa   2220

ggagtacatt gaagggagat tggcacctag tggctgggag cttgccagga acccagtggc   2280

cagggagcgt ggcacttacc tttgtccctt gcttcattct tgtgagatga taaaactggg   2340

cacagctctt aaataaaata taaatgaaca aactttcttt tatttccaaa aaaaaaaaaa   2400

aaaaa                                                               2405


<210>  622
<211>  4725
<212>  DNA
<213>  Human

<400>  622
caattcggcc tcgctccttg tgattgcgct aaaccttccg tcctcagctg agaacgctcc     60

accacctccc cggatcgctc atctcttggc tgccctccca ctgttcctga tgttatttta    120

ctccccgtat cccctactcg ttcttcacaa ttctgtaggt gagtggttcc agctggtgcc    180

tggcctgtgt ctcttggatg ccctgtggct tcagtccgtc tcctgttgcc caccacctcg    240

tccctgggcc gcctgatacc ccagcccaac agctaaggtg tggatggaca gtagggggct    300

ggcttctctc actggtcagg ggtcttctcc cctgtctgcc tcccggagct aggactgcag    360

aggggcctat catggtgctt gcaggccccc tggctgtctc gctgttgctg cccagcctca    420

cactgctggt gtcccacctc tccagctccc aggatgtctc cagtgagccc agcagtgagc    480

agcagctgtg cgcccttagc aagcacccca ccgtggcctt tgaagacctg cagccgtggg    540

tctctaactt cacctaccct ggagcccggg atttctccca gctggctttg gacccctccg    600

ggaaccagct catcgtggga gccaggaact acctcttcag actcagcctt gccaatgtct    660

ctcttcttca ggccacagag tgggcctcca gtgaggacac gcgccgctcc tgccaaagca    720

aagggaagac tgaggaggag tgtcagaact acgtgcgagt cctgatcgtc gccggccgga    780

aggtgttcat gtgtggaacc aatgcctttt cccccatgtg caccagcaga caggtgggga    840

acctcagccg gactattgag aagatcaatg gtgtggcccg ctgcccctat gacccacgcc    900

acaactccac agctgtcatc tcctcccagg gggagctcta tgcagccacg gtcatcgact    960

tctcaggtcg ggaccctgcc atctaccgca gcctgggcag tgggccaccg cttcgcactg   1020

cccaatataa ctccaagtgg cttaatgagc caaacttcgt ggcagcctat gatattgggc   1080

tgtttgcata cttcttcctg cgggagaacg cagtggagca cgactgtgga cgcaccgtgt   1140

actctcgcgt ggcccgcgtg tgcaagaatg acgtgggggg ccgattcctg ctggaggaca   1200

catggaccac attcatgaag gcccggctca actgctcccg cccgggcgag gtccccttct   1260

actataacga gctgcagagt gccttccact tgccggagca ggacctcatc tatggagttt   1320

tcacaaccaa cgtaaacagc atcgcggctt ctgctgtctg cgccttcaac ctcagtgcta   1380

tctcccaggc tttcaatggc ccatttcgct accaggagaa ccccagggct gcctggctcc   1440

ccatagccaa ccccatcccc aatttccagt gtggcaccct gcctgagacc ggtcccaacg   1500

agaacctgac ggagcgcagc ctgcaggacg cgcagcgcct cttcctgatg agcgaggccg   1560

tgcagccggt gacacccgag ccctgtgtca cccaggacag cgtgcgcttc tcacacctcg   1620

tggtggacct ggtgcaggct aaagacacgc tctaccatgt actctacatt ggcaccgagt   1680

cgggcaccat cctgaaggcg ctgtccacgg cgagccgcag cctccacggc tgctacctgg   1740

aggagctgca cgtgctgccc cccgggcgcc gcgagcccct gcgcagcctg cgcatcctgc   1800

acagcgcccg cgcgctcttc gtggggctga gagacggcgt cctgcgggtc ccactggaga   1860

ggtgcgccgc ctaccgcagc cagggggcat gcctgggggc ccgggacccg tactgtggct   1920

gggacgggaa gcagcaacgt tgcagcacac tcgaggacag ctccaacatg agcctctgga   1980

cccagaacat caccgcctgt cctgtgcgga atgtgacacg ggatgggggc ttcggcccat   2040

ggtcaccatg gcaaccatgt gagcacttgg atggggacaa ctcaggctct tgcctgtgtc   2100

gagctcgatc ctgtgattcc cctcgacccc gctgtggggg ccttgactgc ctggggccag   2160

ccatccacat cgccaactgc tccaggaatg gggcgtggac cccgtggtca tcgtgggcgc   2220

tgtgcagcac gtcctgtggc atcggcttcc aggtccgcca gcgaagttgc agcaaccctg   2280

ctccccgcca cgggggccgc atcttcgtgg gcaagagccg ggaggaacgg ttctgtaatg   2340

agaacacgcc ttgcccggtg cccatcttct gggcttcctg gggctcctgg agcaagtgca   2400

gcagcaactg tggagggggc atgcagtcgc ggcgtcgggc ctgcgagaac ggcaactcct   2460

gcctgggctg cggcgagttc aagacgtgca accccgaggg ctgccccgaa gtgcggcgca   2520

acaccccctg gacgccgtgg ctgcccgtga acgtgacgca gggcggggca cggcaggagc   2580

agcggttccg cttcacctgc cgcgcgcccc ttgcagaccc gcacggcctg cagttcggca   2640

ggagaaggac cgagacgagg acctgtcccg cggacggctc cggctcctgc gacaccgacg   2700

ccctggtgga ggtcctcctg cgcagcggga gcacctcccc gcacacggtg agcgggggct   2760

gggccgcctg gggcccgtgg tcgtcctgct cccgggactg cgagctgggc ttccgcgtcc   2820

gcaagagaac gtgcactaac ccggagcccc gcaacggggg cctgccctgc gtgggcgatg   2880

ctgccgagta ccaggactgc aacccccagg cttgcccagt tcggggtgct tggtcctgct   2940

ggacctcatg gtctccatgc tcagcttcct gtggtggggg tcactatcaa cgcacccgtt   3000

cctgcaccag ccccgcaccc tccccaggtg aggacatctg tctcgggctg cacacggagg   3060

aggcactatg tgccacacag gcctgcccag gctggtcgcc ctggtctgag tggagtaagt   3120

gcactgacga cggagcccag agccgaagcc ggcactgtga ggagctcctc ccagggtcca   3180

gcgcctgtgc tggaaacagc agccagagcc gcccctgccc ctacagcgag attcccgtca   3240

tcctgccagc ctccagcatg gaggaggcca ccgactgtgc aggtaaaaga aaccggacct   3300

acctcatgct gcggtcctcc cagccctcca gcaccccact ccaaagtctg gactctttcc   3360

acatcctgct ccagacagcc aagctttgtt ggggtcccca ctgctttgag atgggttcaa   3420

tctcatccac ttggtggcca cgggcatctc ctgcttcttg ggctctgggc tcctgaccct   3480

agcagtgtac ctgtcttgcc agcactgcca gcgtcagtcc caggagtcca cactggtcca   3540

tcctgccacc cccaaccatt tgcactacaa gggcggaggc accccgaaga atgaaaagta   3600

cacacccatg gaattcaaga ccctgaacaa gaataacttg atccctgatg acagagccaa   3660

cttctaccca ttgcagcaga ccaatgtgta cacgactact tactacccaa gccccctgaa   3720

caaacacagc ttccggcccg aggcctcacc tggacaacgg tgcttcccca acagctgata   3780

ccgccgtcct ggggacttgg gcttcttgcc ttcataaggc acagagcaga tggagatggg   3840

acagtggagc cagtttggtt ttctccctct gcactaggcc aagaacttgc tgccttgcct   3900

gtggggggtc ccatccggct tcagagagct ctggctggca ttgaccatgg gggaaagggc   3960

tggtttcagg ctgacatatg gccgcaggtc cagttcagcc caggtctctc atggttatct   4020

tccaacccac tgtcacgctg acactatgct gccatgcctg ggctgtggac ctactgggca   4080

tttgaggaat tggagaatgg agatggcaag agggcaggct tttaagtttg ggttggagac   4140

aacttcctgt ggcccccaca agctgagtct ggccttctcc agctggcccc aaaaaaggcc   4200

tttgctacat cctgattatc tctgaaagta atcaatcaag tggctccagt agctctggat   4260

tttctgccag ggctgggcca ttgtggtgct gccccagtat gacatgggac caaggccagc   4320

gcaggttatc cacctctgcc tggaagtcta tactctaccc agggcatccc tctggtcaga   4380

ggcagtgagt actgggaact ggaggctgac ctgtgcttag aagtccttta atctgggctg   4440

gtacaggcct cagccttgcc ctcaatgcac gaaaggtggc ccaggagaga ggatcaatgc   4500

cataggaggc agaagtctgg cctctgtgcc tctatggaga ctatcttcca gttgctgctc   4560

aacagagttg ttggctgaga cctgcttggg agtctctgct ggcccttcat ctgttcagga   4620

acacacacac acacacactc acacacgcac acacaatcac aatttgctac agcaacaaaa   4680

aagacattgg gctgtggcat tattaattaa agatgatatc cagtc                   4725


<210>  623
<211>  3207
<212>  DNA
<213>  Human

<400>  623
gggcctctgg tagccctggg gacgctgtat ctgtgggctc ttgaatcgcg tcacaaatca     60

gcgaccgaac tctggcggtg gtggttaaga cggcgaaggc ggcagcggcg gcgacagctc    120

tggggtttgc gtctcggggt gtgtcggccg ccgctgctgc ttgggcctgg tatgtacaga    180

tggctggtta ggattctcgg caccattttc cgtttctgcg accggtcggt gccccctgcc    240

cgggccctcc tgaagaggcg gcgctcagac agcactctgt tttctacagt ggacactgat    300

gaaataccag ccaaaagacc aagattagat tgctttattc accaagtgaa aaacagtctc    360

tacaatgctg ccagcttatt tggattccca ttccagctga ccacaaagcc catggtaact    420

tctgcttgta atggaacacg gaatgtggcc ccttcaggag aggtattttc gaactcttca    480

tcttgtgaac tgacaggttc tggatcctgg aacaacatgc tgaaactggg taataaatct    540

cctaatggaa taagtgacta tccaaagatc agagtgacag ttacccgaga tcagccacgc    600

agagtcctgc cttcctttgg ttttactttg aactcagaag gctgtaatag aagaccaggt    660

ggccgtcgcc atagcaaagg taatccagag agttctttaa tgtggaaacc tcaggaacag    720

gctgtaacag agatgatttc tgaagagagt ggcaagggtc tgaggcgtcc ccattgtact    780

gtggaggagg gtgttcaaaa agaggaaaga gagaagtacc gaaagttatt ggaacgactt    840

aaagaaagtg gtcatggaaa ctctgtctgt cctgtaactt caaattatca cagttctcaa    900

agaagtcaga tggacacatt aaagaccaaa ggctgggggg aagagcaaaa tcacggagtc    960

aaaacaactc agtttgttcc aaaacaatat agacttgttg aaacaagggg acctctatgt   1020

tcattgagaa gtgaaaagag gtgttcaaag gggaaaatta ctgatacaga gacgatggtc   1080

ggaatcagat ttgaaaatga aagtaggagg ggataccaac tggagcctga cctatcagaa   1140

gaagtgtcgg cccgactccg cctgggcagt ggaagcaatg gcttactcag gaggaaagtg   1200

tcaataattg agacaaagga aaagaattgc tcaggcaaag agagggacag aagaacggac   1260

gatctccttg aacttacaga ggacatggaa aaggaaatca gtaatgccct aggccatggc   1320

ccacaggatg aaatcctaag tagtgctttc aaattgcgaa ttactcgagg agatattcag   1380

acattaaaga actatcactg gctcaatgat gaagtcatta atttttacat gaatcttctg   1440

gtggaaagaa ataaaaagca aggctatcca gcacttcatg tattcagtac tttcttctat   1500

cctaaattaa agtctggggg ttaccaagca gtgaaacgat ggaccaaagg ggtaaatctc   1560

tttgaacaag aaattattct ggtgcctatt catcggaagg tacattggag cctggtggtg   1620

attgacctaa gaaaaaagtg tcttaaatat ctggattcta tgggacaaaa gggccacagg   1680

atctgtgaga ttctccttca gtatttacag gatgaaagta agaccaaaag aaatagtgat   1740

ctgaatcttt tagagtggac ccatcacagc atgaaaccac acgagattcc tcaacagctg   1800

aatgggagtg attgtggaat gtttacttgt aaatatgcag attatatttc tagggacaaa   1860

cctatcacat ttactcagca ccagatgcct ctcttccgga agaagatggt gtgggaaatc   1920

cttcatcagc agttgctgtg agaaaacttt gcctggtccc tctagctgct ggtggttctt   1980

tcacagacat ttccatatac ctcatgcatt gtgggttaaa aagtccctgc atcacttctg   2040

ttctcacagg tactgagctg tcaaaagtgc atgaaggcct ctcactgtac tctagtcctg   2100

acttggggtg cagagggctg cttgcaatcc tgtttgtaag gctgtgcctg ctcagagctt   2160

tggactgttc aacccacaca agaacaaacg ctaactaata ttttttttaa gagattcttt   2220

tccctatgaa tgtgggaaat gcaggattta ttctgtgaat tgtttgtttc tgtgtgtttg   2280

ttcagcgtat tcattcactc actcgtttgc aaacataatg ggcagtggtc atttactgct   2340

gctcttttac agttagctct aaattacttg tttgaactat ttatttctga aaggaatgtt   2400

actcaagctg ccactccctg ctgaagagca ggagggaact ctcactgggg gcggaaggaa   2460

gtggagctgg agcagtaact gccaacatga agctggaggg tttgggattt tttttgtttt   2520

tgtttttttg aggctcaaaa aatgctggga gaaatgaaaa tgctgtggga tagggctcct   2580

gttgcctttc agaggaagtc tgacactaca gcgttggcac agtgccgtga acagtggaac   2640

tgtgcccaag ggactctgat tatccaagca tcttccgaag agtgttgtgg tcaccttaaa   2700

gagacttccc cttctggaaa tgtggtgact tggcttagtc ttcaaactgg attcatggat   2760

ttgaagtaac tgtaaaccct aaatcttcat tttcatccca gatctggttg agtataaacc   2820

tcagaattgt aggggctggc ctgagctgtt tatttcaaaa gatactattc aatttaaagc   2880

tatttttcct cagagttttt gttttctata tattaagtct aaattaagtt ttctactcat   2940

taagactaac atctccccac tccatcccca ctgaaatttg tggaagaaaa tttagtactt   3000

ggctctgagg ttgccagtta tacaataatc tattttgcat atgaaagttt gtatttaact   3060

tttttgttca ttaaaaacct tactgatatg gttataactt cagacagttt agagttggtc   3120

agaacatatt ttgcaagatc tagtgcctag tgttgctttt ctgatgtaat aaaaggtggt   3180

ctggcagaac ctaaaaaaaa aaaaaaa                                       3207


<210>  624
<211>  1692
<212>  DNA
<213>  Human

<400>  624
tagacttgtc ggcgctcgat tgaggagcgt ggctacgttg cttccggtgc ctggctccgt     60

ttcctgcttt tggttcttac agtagtcggc gtaggcctta ggtgggttcg tgcgccttct    120

acctcgctgt ttcggttttc ctggctcctc ggcccttttc tcccctgttg cagctgggag    180

cggacgaagc gcgaagctgg gattttttac tgtctcctga agaatttaac acaaacatgg    240

atatcagacc aaatcataca atttatatca acaatatgaa tgacaaaatt aaaaaggaag    300

aattgaagag atccctatat gccctgtttt ctcagtttgg tcatgtggtg gacattgtgg    360

ctttaaagac catgaagatg agggggcagg cctttgtcat atttaaggaa ctgggctcat    420

ccacaaatgc cttgagacag ctacaaggat ttccatttta tggtaaacca atgcgaatac    480

agtatgcaaa aacagattcg gatataatat caaaaatgcg tggaactttt gctgacaaag    540

aaaagaaaaa agaaaagaaa aaagccaaaa ctgtggaaca gactgcaaca accacaaaca    600

aaaagcctgg ccagggaact ccaaattcag ctaataccca aggaaattca acaccaaatc    660

ctcaggtccc tgattaccct ccaaactata ttttattcct taataactta ccagaagaga    720

ctaatgagat gatgttatcc atgctgttta atcagttccc tggcttcaag gaagtacgtc    780

tggtaccagg gaggcatgac attgcttttg ttgaatttga aaatgatggg caggctggag    840

ctgccaggga tgctttacag ggatttaaga tcacaccgtc ccatgctatg aagatcacct    900

atgccaagaa ataacatttg ggatagtcgt ctttaaaaga cttggtgtta tttacagtgt    960

ttgttttgat aacatttggc tgggtcattt taatagttag agatgaggag gagtaaaagt   1020

gaaatttttg tgaaggactt aaattatcca gtgtttcttt agccttggtg aactatgaaa   1080

tacgaaggcc ttaattttgt acaataaact tttatttgta ttctgtgtat ataatgcttt   1140

cttgattgac ccatctccct atcatcaaat gacttctagt ctagaacaca cttaaggttt   1200

ataaacttgt gtaataggat gcttttctag tgttactttg gaggagctaa ttatacaaca   1260

tcattgaacc attcaataaa agttaagtaa aattagatca cagaagctag tagatgactg   1320

ttgtattaat ggtaacaatg attgttctgg gtattagaag aaaatgagac ccaggcagga   1380

tctaaatttg atctttgtat ccttttaaga aatgaatata ttattttgct gctagtaggg   1440

attccacaag ttttcttcat tcagtattaa ataaaggctg ttcttactgt ttactgagaa   1500

aacagaaagg gaatgctatc ttcacacttt gcatttaatg ctgtttcctt catgaggcag   1560

gactgttcta aggttaatat gcaatctctt tattgaaaga cctccagggt aaaaattttt   1620

tgatctatag tctcttttcc cccttaagac aaatagactg attaataaag agttgccagt   1680

gaaaaaaaaa aa                                                       1692


<210>  625
<211>  2058
<212>  DNA
<213>  Human

<400>  625
gagaggcgcc caggcggcgg cggcggcggc ccagcttctt ctttcctcgc acagccaggc     60

ggcccctgct cgagtcccgc gtcgccatgg ccgcggttcc cgagttgctg cagcagcagg    120

aggaggaccg cagcaagctg agatctgtat ctgtggacct gaatgttgat ccctcgcttc    180

agattgacat acctgatgcg ctcagtgaga gagacaaagt caaatttaca gtgcacacaa    240

agaccacact gcccacgttt cagagcccag agttttctgt tacaaggcaa catgaagact    300

ttgtgtggct acatgacact cttattgaaa caacagacta tgctgggctt attattccac    360

ctgctcctac gaagcccgac tttgatggtc ctcgagagaa gatgcagaaa ctgggagaag    420

gtgaagggtc tatgaccaaa gaagaatttg ccaagatgaa acaagaactg gaagctgagt    480

atctcgctgt gtttaagaag actgtgtcct cccatgaagt ctttcttcag cggctttctt    540

ctcaccctgt tctcagtaaa gatcgcaact ttcatgtttt cctggaatat gatcaggatc    600

taagtgttag gcggaaaaat actaaagaga tgtttggtgg cttcttcaaa agtgtggtga    660

aaagtgctga tgaagtcctt tttactggag ttaaggaggt agatgacttc tttgagcaag    720

agaagaactt ccttattaac tattacaata ggatcaaaga ttcttgtgtg aaagctgaca    780

aaatgaccag atctcataaa aatgttgccg atgactatat ccacaccgca gcctgcttac    840

atagcctggc tttagaagag cccacagtca tcaaaaagta cctattgaag gttgctgagc    900

tatttgaaaa actaaggaaa gtagagggtc gagtttcatc agatgaagat ttgaagctaa    960

cagagctcct ccgatactac atgctcaaca ttgaagctgc taaggatctc ttatacagac   1020

gcaccaaagc cctcattgac tatgagaact caaacaaagc tctggataag gcccggttaa   1080

agagcaaaga cgtcaagttg gctgaggcac accagcagga gtgctgccag aaatttgaac   1140

aactttccga atctgcaaaa gaagaactga taaatttcaa acggaagaga gtggcagcat   1200

ttagaaagaa tctaattgaa atgtctgaac tggaaataaa acatgccagg aacaatgtct   1260

cccttttgca gagctgtatt gacttgttca agaataactg atatgccttc actcagaaga   1320

aaagaaatga atgtgaaaga aagccaagca tcacttgcac ttaaatcatt accacggaag   1380

atatattagc ttcaacttta gtttaaaatt atgtgaataa atattttgat ttctacaaat   1440

cttaacattt aaccatgttg gtttaaaaat attattgctt gctacttgga cataactaat   1500

ttttccttgt gcatttaata cctctgggca gaatccaaat actgggttct cccgtagttc   1560

gtctttagtt actaagaaag ggtgtaggac acattagcct tctggaaaca agtagaagcc   1620

atcacctggc ccatgtccct acaaacccat gattgtcagg gaggtgccag ttacagcagg   1680

tgattcagct acttgaggtc ggtaacagac cttccattcc tcactgaagg tggggtttgt   1740

gtttttgttt tgccctgtta ctccactggt agtcatctgg tgtttgtact ataacaacag   1800

caagaaaatc tcatttatct ttatatactc tttgcacctc ctttttttag tcgagatata   1860

aatatttgag gggagagaaa tatctacagg tatatatgga aacaaataat gtggtctgct   1920

ttataagatg gccagatcta cattaggaaa agtataagcc ccctccctaa tggccgctgg   1980

ggggtgaggg cggtgtgttg tatgtctttg ggtgtttgtt tttttataaa gcatataata   2040

aaataatcgt gctactaa                                                 2058


<210>  626
<211>  2746
<212>  DNA
<213>  Human

<400>  626
ggctccgact tggactccct gctccgctgc tgccgcttcg gccccgcacg cagccagccg     60

ccagccgccc gcccggccca gctcccgccg cggccccttg ccgcggtccc tctcctggtc    120

ccctcccggt tggtccgggg gtgcgcaggg ggcagggcgg gcgcccaggg gaagctcgag    180

ggacgcgcgc gcgaaggctc ctttgtggac ttcacggccg ccaacatctg ggcgcagcgc    240

gggccaccgc tggccgtctc gccgccgcgt cgccttgggg acccgagggg gctcagcccc    300

aaggacggag acttcgattc gggaccagcc ccccgggatg cggtagcggc cgctgtgcgg    360

aggccgcgaa gcagctgcag ccgccgccgc gcagatccac gctggctccg tgcgccatgg    420

tcacccacag caagtttccc gccgccggga tgagccgccc cctggacacc agcctgcgcc    480

tcaagacctt cagctccaag agcgagtacc agctggtggt gaacgcagtg cgcaagctgc    540

aggagagcgg cttctactgg agcgcagtga ccggcggcga ggcgaacctg ctgctcagtg    600

ccgagcccgc cggcaccttt ctgatccgcg acagctcgga ccagcgccac ttcttcacgc    660

tcagcgtcaa gacccagtct gggaccaaga acctgcgcat ccagtgtgag gggggcagct    720

tctctctgca gagcgatccc cggagcacgc agcccgtgcc ccgcttcgac tgcgtgctca    780

agctggtgca ccactacatg ccgccccctg gagccccctc cttcccctcg ccacctactg    840

aaccctcctc cgaggtgccc gagcagccgt ctgcccagcc actccctggg agtcccccca    900

gaagagccta ttacatctac tccgggggcg agaagatccc cctggtgttg agccggcccc    960

tctcctccaa cgtggccact cttcagcatc tctgtcggaa gaccgtcaac ggccacctgg   1020

actcctatga gaaagtcacc cagctgccgg ggcccattcg ggagttcctg gaccagtacg   1080

atgccccgct ttaaggggta aagggcgcaa agggcatggg tcgggagagg ggacgcaggc   1140

ccctctcctc cgtggcacat ggcacaagca caagaagcca accaggagag agtcctgtag   1200

ctctgggggg aaagagggcg gacaggcccc tccctctgcc ctctccctgc agaatgtggc   1260

aggcggacct ggaatgtgtt ggagggaagg gggagtacca cctgagtctc cagcttctcc   1320

ggaggagcca gctgtcctgg tgggacgata gcaaccacaa gtggattctc cttcaattcc   1380

tcagcttccc ctctgcctcc aaacagggga cacttcggga atgctgaact aatgagaact   1440

gccagggaat cttcaaactt tccaacggaa cttgtttgct ctttgatttg gtttaaacct   1500

gagctggttg tggagcctgg gaaaggtgga agagagagag gtcctgaggg ccccagggct   1560

gcgggctggc gaaggaaatg gtcacacccc ccgcccaccc caggcgagga tcctggtgac   1620

atgctcctct ccctggctcc ggggagaagg gcttggggtg acctgaaggg aaccatcctg   1680

gtaccccaca tcctctcctc cgggacagtc accgaaaaca caggttccaa agtctacctg   1740

gtgcctgaga gcccagggcc cttcctccgt tttaaggggg aagcaacatt tggaggggat   1800

ggatgggctg gtcagctggt ctccttttcc tactcatact ataccttcct gtacctgggt   1860

ggatggagcg ggaggatgga ggagacggga catctttcac ctcaggctcc tggtagagaa   1920

gacaggggat tctactctgt gcctcctgac tatgtctggc taagagattc gccttaaatg   1980

ctccctgtcc catggagagg gacccagcat aggaaagcca catactcagc ctggatgggt   2040

ggagaggctg agggactcac tggagggcac caagccagcc cacagccagg gaagtgggga   2100

gggggggcgg aaacccatgc ctcccagctg agcactggga atgtcagccc agtaagtatt   2160

ggccagtcag gcgcctcgtg gtcagagcag agccaccagg tcccactgcc ccgagccctg   2220

cacagccctc cctcctgcct gggtggggga ggctggaggt cattggagag gctggactgc   2280

tgccaccccg ggtgctcccg ctctgccata gcactgatca gtgacaattt acaggaatgt   2340

agcagcgatg gaattacctg gaacagtttt ttgtttttgt ttttgttttt gtttttgtgg   2400

gggggggcaa ctaaacaaac acaaagtatt ctgtgtcagg tattgggctg gacagggcag   2460

ttgtgtgttg gggtggtttt tttctctatt tttttgtttg tttcttgttt tttaataatg   2520

tttacaatct gcctcaatca ctctgtcttt tataaagatt ccacctccag tcctctctcc   2580

tcccccctac tcaggccctt gaggctatta ggagatgctt gaagaactca acaaaatccc   2640

aatccaagtc aaactttgca catatttata tttatattca gaaaagaaac atttcagtaa   2700

tttataataa agagcactat tttttaatga aaaaaaaaaa aaaaaa                  2746


<210>  627
<211>  1542
<212>  DNA
<213>  Human

<400>  627
gctctcggcc aatgcggagc cccgcgcgga ggtcacgtgc ctctgtttgg cgcttttgtg     60

cgcgcccggg tctgttggtg ctcagagtgt ggtcaggcgg ctcggactga gcaggacttt    120

ccttatccca gttgattgtg cagaatacac tgcctgtcgc ttgtcttcta ttcaccatgg    180

cttcttctga tatccaggtg aaagaactgg agaagcgtgc ctcaggccag gcttttgagc    240

tgattctcag ccctcggtca aaagaatctg ttccagaatt ccccctttcc cctccaaaga    300

agaaggatct ttccctggag gaaattcaga agaaattaga agctgcagaa gaaagacgca    360

agtcccatga agctgaggtc ttgaagcagc tggctgagaa acgagagcac gagaaagaag    420

tgcttcagaa ggcaatagaa gagaacaaca acttcagtaa aatggcagaa gagaaactga    480

cccacaaaat ggaagctaat aaagagaacc gagaggcaca aatggctgcc aaactggaac    540

gtttgcgaga gaaggataag cacattgaag aagtgcggaa gaacaaagaa tccaaagacc    600

ctgctgacga gactgaagct gactaatttg ttctgagaac tgactttctc cccatcccct    660

tcctaaatat ccaaagactg tactggccag tgtcatttta ttttttccct cctgacaaat    720

attttagaag ctaatgtagg actgtatagg tagatccaga tccagactgt aagatgttgt    780

tttaggggct aaaggggaga aactgaaagt gttttactct ttttctaaag tgttggtctt    840

tctaatgtag ctatttttct tgttgcatct tttctacttc agtacacttg gtgtactggg    900

ttaatggcta gtactgtatt ggctctgtga aaacatattt gtgaaaagag tatgtagtgg    960

cttcttttga actgttagat gctgaatatc tgttcacttt tcaatcccaa ttctgtccca   1020

atcttaccag atgctactgg acttgaatgg ttaataaaac tgcacagtgc tgttggtggc   1080

agtgacttct tttgagttag gttaataaat caagccatag agcccctcct ggttgatact   1140

tgttccagat ggggcctttg gggctggtag aaatacccaa cgcacaaatg accgcacgtt   1200

ctctgccccg tttcttgccc cagtgtggtt tgcattgtct ccttccacaa tgactgcttt   1260

gtttggatgc ctcagcccag gtcagctgtt actttctttc agatgtttat ttgcaaacaa   1320

ccattttttg ttctgtgtcc cttttaaaag gcagattaaa agcacaagcg tgtttctaga   1380

gaacagttga gagagaatct caagattcta cttggtggtt tgcttgctct acgttacagg   1440

tggggcatgt cctcatcctt tcctgccata aaagctatga cacgagaatc agaatattaa   1500

taaaacttta tgtactgctg tagcaaaaaa aaaaaaaaaa aa                      1542


<210>  628
<211>  1352
<212>  DNA
<213>  Human

<400>  628
gaggaagaga gcagctcgct tctaactgga ctgcacgttg gtgacagcgt cccaagctgg     60

tgacagaccc actctgtaac tttcagctag attcagccac cagatcccag aaacatgacc    120

cttgctgcct acaaagagaa gatgaaggag ctcccgctgg tgtccttgtt ctgctcctgc    180

ttcctggccg atcccctgaa taagtcgtcc tacaaatatg aaggctggtg tgggagacag    240

tgtaggagga aggatgaaag ccagcggaaa gacagtgctg actggagaga aagaagagct    300

caggcagaca cggtggacct gaattggtgc gtcatttccg acatggaagt catcgagctg    360

aacaaatgca cctcgggcca atcctttgaa gtcatcctga agccaccctc ctttgatggg    420

gttcccgagt tcaacgcctc cctgccaagg cggcgagacc catccctgga agagatccag    480

aagaaactag aagcggctga ggagcgaagg aagtaccagg aagcggagct cctgaaacac    540

ctagcagaga aacgggaaca tgagagagag gtgatccaaa aggccattga ggaaaacaac    600

aacttcatca agatggctaa ggaaaaactg gcccagaaga tggaatccaa caaggagaac    660

agggaggccc acctcgccgc catgttggaa cggctgcaag agaaggacaa gcacgccgag    720

gaggtgcgga aaaacaagga gctgaaggaa gaggcctcca ggtaaagcct agaggccaaa    780

gaactttcca ggtcagccgg acagctccag cagctccacg ttccaggcag cctcgcccgc    840

cggctgcgct cccagcactg gggtttgggg ggaggggggt ggccaagggg cgtttcctct    900

gcttttggtg tttgtacatg ttaagaattg accagtgaag ccatcctatt tgtttccggg    960

gaacaatgac ggggtgggag aggggagagg agagagtttg ggaaagggag atggagaaga   1020

actcaaggac attgcaaccc tgcccggcgc agatctgatt ttcacatctc tacctggaca   1080

ttgagcctcc aggcaccatg ttgaggagag atgaaaacca gggcggtaga acttcagggt   1140

gaaggacaga gtcctgggtg gggcagcggc tgcagggcgc accagagaac ccagccagag   1200

gggttgtgag taccagtggt gttgcttcca ccctgcagca ggtgggatga ggtctgtgtg   1260

tgtgtgtgaa ccatcatttt ttgatcatca tgaccaatga aacattgact ccaaaaaaaa   1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa                                 1352


<210>  629
<211>  3122
<212>  DNA
<213>  Human

<400>  629
gcggccgccc agagcggcgg cgggggcggc ggggcgcggg gcgcgggggc ccagctgagc     60

cggccgtcgg agtgagaccc tgcggcagag acgacggagg cggaagcaac ccgatcccgg    120

aggcggcggc ggcgggggga gccggagccg cctgggatgt tcagtcatga aacgagtgcg    180

taccgagcag attcagatgg cagtgtcctg ctacctcaaa cgccggcagt acgtggactc    240

agatggtccc ctgaagcaag gactgcggct gtcacagact gctgaagaga tggcggccaa    300

tctaacagtg caatcagaat ctggttgtgc caacatagtg tctgcagccc cttgccaggc    360

agaaccccag caatatgaag tacagtttgg acgactgcgg aattttctca ctgattctga    420

ttcccagcat agccacgaag tgatgcctct cctctatcct ctctttgtct acctccatct    480

caacctggtc caaaacagtc cgaagagcac agtggaaagt ttttacagcc gcttccatgg    540

aatgtttctg cagaatgcta gccagaagga tgtcattgag cagctacaga ccactcaaac    600

catccaggac atcctatcta acttcaagct tcgagcattc ctagataaca agtacgtggt    660

ccgtctccaa gaagacagct acaactacct tatccgctac ctccaaagtg acaacaatac    720

tgccctgtgc aaagtcctca ccttacatat tcatcttgac gtgcagcctg ccaagagaac    780

agactatcag ctgtatgcca gtggcagctc ctcccgcagt gagaacaacg gtttggagcc    840

ccccgacatg cccagcccta ttctgcagaa cgaggctgcc ctagaggtct tacaggagag    900

cattaagcga gtcaaggatg ggcctccctc cctcactacc atctgcttct atgccttcta    960

taacacagag cagctgttga acactgcaga aatctccccc gatagcaagc tgcttgctgc   1020

tgggtttgac aactcctgta taaaactttg gagtttacga tccaagaagt taaaatcaga   1080

gccccaccaa gtagacgtgt cccgcatcca tttggcttgt gatattctgg aggaggagga   1140

tgatgaggat gataatgcag gcacggagat gaagatactg cggggccact gcggaccagt   1200

gtacagcacg aggttcctcg cggacagctc agggttgctc tcttgttctg aagacatgtc   1260

catcagatac tgggatctgg ggagtttcac caacactgtg ttgtaccaag gacatgccta   1320

tcctgtgtgg gatctggaca tcagtccata tagcctgtac ttcgccagcg ggtcccacga   1380

ccgcaccgcc aggctgtggt catttgatcg gacgtacccg ctgaggatat atgcaggaca   1440

cctggcagat gtggactgtg tcaaattcca ccctaattca aactacttgg ccacgggctc   1500

aaccgacaag accgtccggc tgtggagcgc tcagcagggg aactcggtga ggcttttcac   1560

aggccaccgt ggccccgtgc tttctctcgc cttttctccc aacggtaagt acttggcgtc   1620

tgctggcgag gaccagcggt tgaagctgtg ggacttggcc tctgggaccc tttataaaga   1680

gttgagaggc cacacagaca atatcaccag cctcaccttc agtccagaca gcggcttgat   1740

tgcctctgcc tccatggaca actcggtgcg cgtctgggac atcaggaaca cttactgcag   1800

tgcacctgcc gacggctcct ccagcgagct cgtgggcgtg tacaccgggc agatgagcaa   1860

cgtcctgagc gtgcagttca tggcctgtaa ccttcttctg gtgactggaa ttacacaaga   1920

aaatcaggaa cattaatttt ttaactttgt tggaacggac tggggtaaca gtggaaagcc   1980

tccagttgca atccttcaat gagctgagat tgaatcattg actgtgaaag agccccctcc   2040

tcccctctct cctgggccct cattccgggc aggtccccct tcactcagcc ccccagtgtc   2100

gaaggccaag gttggggagg ggaacaggag agaggcaatg atgagtgatc aagaattaga   2160

gtgccctgga ggtcactcac aagtcctcat ggagactctg ccgtgacctc gcgcatgcga   2220

gcaccttcct gtctctcatt ttcaccatct gactggggct aggtttggtt agagggcggc   2280

tgtagagcac cctcaggaga agtggcgccg caggggtcac gcatggtcca gccctcaggt   2340

gggagggaag tccttgttgg cagagggatg tggggcggga atgaggaaag gggagggcat   2400

gatcctggca aatagtcttt ccttttccgt aattacagag aaccaggatt ttttttaatt   2460

attgttatta taattataat tattattatt attgacatga ggaaacctag cactggcaga   2520

gggcaccttc tctgctttta atctttcagg tttgactcct ggcactggtt ttgatacttg   2580

gaattttgag gttcagggaa ttcagagaat ttggtagcac agtgtattgg gagaaaggga   2640

aatttcgggt gacagattga tcaccctggc tgacatgttt ctggaagtgg gtgggtgggt   2700

ttgattgaga acactttggg ctcctgcagt gatggtggga aagaaaaatt ctttccaaag   2760

ctgcacttct cttaataatt ctctcccctc aaaagaaaga ttatgataaa gaataatttg   2820

gagtaataag taacaagata gaattagaaa aatgttgaat ttctgaatga ccattcagag   2880

gtgtggcttt ttccacgtct ttttctcctg caatgaactg ctcccacgtc ctgcactgca   2940

ataccagtct aatgaacact ttgtgaaaca aatcgtaagt atgtacgcac gcatatcaaa   3000

ctatgctctg aggataaagc aagttctaat ttgtggaaaa aggattaaat atttctgttt   3060

tctgaaaaga gttattttgt attttgtttt ctattaaaat gtatttagtt tcaaaaaaaa   3120

aa                                                                  3122


<210>  630
<211>  1294
<212>  DNA
<213>  Human

<400>  630
tgggctgcgg cattcacgtg atctgcacgg gcgcagatgt aggcaccggt ccgagtgcct     60

gccctctgtc cccgcggctg ggtctcgtct gctccggttc ctgggctcct aattcttggt    120

ccagcttctt ccaggtctgc gcgtctgttg ttcccagcgc tctgcgaagc ctgaaaagga    180

ggagcaacct gtccagaatc cccgcaggac aggaaaagga ggggaaatct cgacatggaa    240

aaactctaca gtgaaaatga aggaatggct tcaaaccaag gaaagatgga aaatgaagaa    300

cagccacaag acgagagaaa gccagaagta acttgtactc tggaagacaa gaagttagaa    360

aacgagggaa agacagaaaa caagggcaaa acaggagatg aggaaatgtt aaaggataaa    420

ggaaagccag agagtgaggg agaggcaaaa gaaggaaagt cagagaggga gggagagtca    480

gagatggagg gaggatcaga gagagaggga aaaccagaga tagagggaaa gccagagagt    540

gaaggagagc cagggagtga aacaagggct gcaggaaagc gcccagctga ggatgatgta    600

cccaggaaag ccaaaagaaa aactaataag gggctggctc attacctcaa ggagtataaa    660

gaggccatac atgatatgaa tttcagcaat gaggacatga taagagaatt tgacaatatg    720

gctaaggtgc aggatgagaa gagaaaaagc aaacagaaat tgggggcgtt tttgtggatg    780

caaagaaatt tacaggaccc cttctaccct agaggtccaa gggaattcag gggtggctgc    840

agggccccac gaagggacat tgaagacatt ccttatgtgt agtgtccctg gcaggcattt    900

accaggccat gtgctttaac gttacggtaa tactttactt taggcatccc tcctgttgct    960

agcagccttt tgacctatct gcaatgcagt gttctcagta ggaaatgttc atctgttaca   1020

tggaaaaaat gttgatggtg cattgtaaaa ttaaaaaaca caacttgcag aaccaaatat   1080

atggcatcag tacatttttg taaaactaca aagatactta cctagtaata tagtatagaa   1140

aacaattctg aaagctgtgt ccactaaaag attaacagtg gttatctctg ggtgattttt   1200

tctgttcttt tttgttcatc tgtccatttt tctcctaaaa acagatttct ttagtcataa   1260

aaataataaa atataaagta ttggaaaaaa aaaa                               1294


<210>  631
<211>  2356
<212>  DNA
<213>  Human

<400>  631
cagctcctca cgctcggtgc ccgcgccccg cagcggcagc gcagaacgca ccgcctctgc     60

cagagcccgg gaagcgctcg ggcgaagagg aggagccaag ggtaccgagc gggtggagtc    120

gggagccgga gagcggtgga ggcggatttc ctgggcccgg ccctctggcg ctaccatggc    180

gtttggcaag agtcaccggg atccctacgc gacctccgtg ggccacctca tagaaaaggc    240

tacatttgct ggagttcaga ctgaagattg gggccagttc atgcacatct gtgacataat    300

taacactacc caggatgggc caaaagatgc agtgaaagct ttgaagaaaa ggatttccaa    360

aaactacaat cataaagaaa tccaacttac cttgtcactt attgacatgt gtgtgcagaa    420

ctgtggtcca agtttccagt ctctgattgt gaagaaggaa tttgttaaag agaatttagt    480

taagctactg aatcccagat acaacttgcc attagacatt cagaatagaa tcttgaattt    540

cattaagact tggtcacagg gcttcccagg aggtgtggat gtaagcgaag tcaaagaagt    600

atacctcgac ctggttaaga aaggcgttca gtttcctccc tcagaagcag aggctgaaac    660

agcaagacaa gagactgctc aaatctcatc aaatcctcca acatctgtcc ctactgcacc    720

agctctttct tctgtaattg ctccaaagaa ctcgactgtt acattggtcc cagaacagat    780

tggaaaactg cacagtgaat tggatatggt gaaaatgaat gtgcgagtga tgtccgccat    840

attgatggag aatactcctg ggtctgaaaa ccatgaagac atagagcttc tgcagaaact    900

ctataaaaca ggtcgggaga tgcaggagag gatcatggac ctgcttgtgg tggtggagaa    960

cgaagatgta actgttgagc taattcaggt gaatgaggat ttgaataatg ctatccttgg   1020

atatgagagg tttactagaa accaacaaag gattttggag caaaataaga accagaagga   1080

agccaccaat actaccagtg agccttctgc cccatctcaa gatctcctcg acctaagtcc   1140

cagtccccgg atgcctaggg ccactctggg agaactcaac accatgaata atcaactttc   1200

aggcttaaat ttcagccttc caagttctga tgtaacaaac aacttaaaac ccagtcttca   1260

tccacagatg aacttgctag ccttggagaa tacagagata cccccgtttg cccaaaggac   1320

cagccaaaac ctcacctcaa gccacgcata tgataatttt ctggaacatt caaattcagt   1380

gtttctacag ccagttagtc tacaaaccat tgcagcagca ccatcaaacc agagtctgcc   1440

acctttgccc agcaatcatc cagcgatgac aaaaagtgat ctccagccac ctaattacta   1500

cgaggtaatg gagtttgatc ccttagctcc tgctgtcact acagaagcta tttatgaaga   1560

aattgatgct caccagcaca aaggagctca aaatgatggt gactgagaag aaagtggatg   1620

atcagctcac taccacatca aaggtgccaa ctctctaaaa cgtagactct gtgcagcttt   1680

gaagcctgga agacaatacc taccaacatg tcaaagccat ggtggcacat ttctgctata   1740

atgaagatta aatagaataa cagttccagg ataacactga ttcctgacaa cagcgtgaga   1800

tttcaacaga acttgtttgg aacaaatact cacttaaaac ttcagcagaa gaaaaattac   1860

ttagtcctta ggccaaccaa tttaactgca gtgtcatgtt tcacaggcct tcctacattt   1920

agaaatcgtc acacagctgt gataagagta gattatttta ctatgaaata attctgaata   1980

gatgaaagca taaaatgtga gaaactgaat gtattattca ggaagaatac tgagtgcctt   2040

catttaacta aagttgaatg taaaagtcaa tttgcacttc tttataatcc tctggtttag   2100

aattataaat tgttaaaacc ttgataattg tcatttaatt atatttcagg tgtcctgaac   2160

aggtcactag actctacatt gggcagcctt taaatatgat tctttgtaat gctaaatagc   2220

ctttttttct ctttttactg caacttaata tttctattta gaacacagaa aatgaaaata   2280

tttagaataa gttgtacatt tgatgacaaa taaatcacta ttaaaacaat ttaatacttt   2340

aaaaaaaaaa aaaaaa                                                   2356


<210>  632
<211>  3685
<212>  DNA
<213>  Human

<400>  632
agtggactca cgcaggcgca ggagactaca cttcccagga actccgggcc gcgttgttcg     60

ctggtacctc cttctgactt ccggtattgc tgcggtctgt agggccaatc gggagcctgg    120

aattgctttc ccggcgctct gattggtgca ttcgactagg ctgcctgggt tcaaaatttc    180

aacgatactg aatgagtccc gcggcgggtt ggctcgcgct tcgttgtcag atctgaggcg    240

aggctaggtg agccgtggga agaaaagagg gagcagctag ggcgcgggtc tccctcctcc    300

cggagtttgg aacggctgaa gttcaccttc cagcccctag cgccgttcgc gccgctaggc    360

ctggcttctg aggcggttgc ggtgctcggt cgccgcctag gcggggcagg gtgcgagcag    420

gggcttcggg ccacgcttct cttggcgaca ggattttgct gtgaagtccg tccgggaaac    480

ggaggaaaaa aagagttgcg ggaggctgtc ggctaataac ggttcttgat acatatttgc    540

cagacttcaa gatttcagaa aaggggtgaa agagaagatt gcaactttga gtcagacctg    600

taggcctgat agactgatta aaccacagaa ggtgacctgc tgagaaaagt ggtacaaata    660

ctgggaaaaa cctgctcttc tgcgttaagt gggagacaat gtcacaagtt aaaagctctt    720

attcctatga tgccccctcg gatttcatca atttttcatc cttggatgat gaaggagata    780

ctcaaaacat agattcatgg tttgaggaga aggccaattt ggagaataag ttactgggga    840

agaatggaac tggagggctt tttcagggca aaactccttt gagaaaggct aatcttcagc    900

aagctattgt cacacctttg aaaccagttg acaacactta ctacaaagag gcagaaaaag    960

aaaatcttgt ggaacaatcc attccgtcaa atgcttgttc ttccctggaa gttgaggcag   1020

ccatatcaag aaaaactcca gcccagcctc agagaagatc tcttaggctt tctgctcaga   1080

aggatttgga acagaaagaa aagcatcatg taaaaatgaa agccaagaga tgtgccactc   1140

ctgtaatcat cgatgaaatt ctaccctcta agaaaatgaa agtttctaac aacaaaaaga   1200

agccagagga agaaggcagt gctcatcaag atactgctga aaagaatgca tcttccccag   1260

agaaagccaa gggtagacat actgtgcctt gtatgccacc tgcaaagcag aagtttctaa   1320

aaagtactga ggagcaagag ctggagaaga gtatgaaaat gcagcaagag gtggtggaga   1380

tgcggaaaaa gaatgaagaa ttcaagaaac ttgctctggc tggaataggg caacctgtga   1440

agaaatcagt gagccaggtc accaaatcag ttgacttcca cttccgcaca gatgagcgaa   1500

tcaaacaaca tcctaagaac caggaggaat ataaggaagt gaactttaca tctgaactac   1560

gaaagcatcc ttcatctcct gcccgagtga ctaagggatg taccattgtt aagcctttca   1620

acctgtccca aggaaagaaa agaacatttg atgaaacagt ttctacatat gtgccccttg   1680

cacagcaagt tgaagacttc cataaacgaa cccctaacag atatcatttg aggagcaaga   1740

aggatgatat taacctgtta ccctccaaat cttctgtgac caagatttgc agagacccac   1800

agactcctgt actgcaaacc aaacaccgtg cacgggctgt gacctgcaaa agtacagcag   1860

agctggaggc tgaggagctc gagaaattgc aacaatacaa attcaaagca cgtgaacttg   1920

atcccagaat acttgaaggt gggcccatct tgcccaagaa accacctgtg aaaccaccca   1980

ccgagcctat tggctttgat ttggaaattg agaaaagaat ccaggagcga gaatcaaaga   2040

agaaaacaga ggatgaacac tttgaatttc attccagacc ttgccctact aagattttgg   2100

aagatgttgt gggtgttcct gaaaagaagg tacttccaat caccgtcccc aagtcaccag   2160

cctttgcatt gaagaacaga attcgaatgc ccaccaaaga agatgaggaa gaggacgaac   2220

cggtagtgat aaaagctcaa cctgtgccac attatggggt gccttttaag ccccaaatcc   2280

cagaggcaag aactgtggaa atatgccctt tctcgtttga ttctcgagac aaagaacgtc   2340

agttacagaa ggagaagaaa ataaaagaac tgcagaaagg ggaggtgccc aagttcaagg   2400

cacttccctt gcctcatttt gacaccatta acctgccaga gaagaaggta aagaatgtga   2460

cccagattga acctttctgc ttggagactg acagaagagg tgctctgaag gcacagactt   2520

ggaagcacca gctggaagaa gaactgagac agcagaaaga agcagcttgt ttcaaggctc   2580

gtccaaacac cgtcatctct caggagccct ttgttcccaa gaaagagaag aaatcagttg   2640

ctgagggcct ttctggttct ctagttcagg aaccttttca gctggctact gagaagagag   2700

ccaaagagcg gcaggagctg gagaagagaa tggctgaggt agaagcccag aaagcccagc   2760

agttggagga ggccagacta caggaggaag agcagaaaaa agaggagctg gccaggctac   2820

ggagagaact ggtgcataag gcaaatccaa tacgcaagta ccagggtctg gagataaagt   2880

caagtgacca gcctctgact gtgcctgtat ctcccaaatt ctccactcga ttccactgct   2940

aaactcagct gtgagctgcg gataccgccc ggcaatggga cctgctctta acctcaaacc   3000

taggaccgtc ttgctttgtc attgggcatg gagagaaccc atttctccag acttttacct   3060

acccgtgcct gagaaagcat acttgacaac tgtggactcc agttttgttg agaattgttt   3120

tcttacatta ctaaggctaa taatgagatg taactcatga atgtctcgat tagactccat   3180

gtagttactt cctttaaacc atcagccggc cttttatatg ggtcttcact ctgactagaa   3240

tttagtctct gtgtcagcac agtgtaatct ctattgctat tgccccttac gactctcacc   3300

ctctccccac tttttttaaa aattttaacc agaaaataaa gatagttaaa tcctaagata   3360

gagattaagt catggtttaa atgaggaaca atcagtaaat cagattctgt cctcttctct   3420

gcataccgtg aatttatagt taaggatccc tttgctgtga gggtagaaaa cctcaccaac   3480

tgcaccagtg aggaagaaga ctgcgtggat tcatggggag cctcacagca gccacgcagc   3540

aggctctggg tggggctgcc gttaaggcac gttctttcct tactggtgct gataacaaca   3600

gggaaccgtg cagtgtgcat tttaagacct ggcctggaat aaatacgttt tgtctttccc   3660

tcaaaaaaaa aaaaaaaaaa aaaaa                                         3685


<210>  633
<211>  1940
<212>  DNA
<213>  Human

<400>  633
ggggcggtgc agaggcggca ggaagatgga gttggggagt tgcctggagg gcgggaggga     60

ggcggcggag gaagagggcg agcctgaggt gaaaaagcgg cgacttctgt gtgtggagtt    120

tgcctcggtc gcaagctgcg atgccgcagt ggctcagtgc ttcctggccg agaacgactg    180

ggagatggaa agggctctga actcctactt cgagcctccg gtggaggaga gcgccttgga    240

acgccgacct gaaaccatct ctgagcccaa gacctatgtt gacctaacca atgaagaaac    300

aactgattcc accacttcta aaatcagccc atctgaagat actcagcaag aaaatggcag    360

catgttctct ctcattacct ggaatattga tggattagat ctaaacaatc tgtcagagag    420

ggctcgaggg gtgtgttcct acttagcttt gtacagccca gatgtgatat ttctacagga    480

agttattccc ccatattata gctacctaaa gaagagatca agtaattatg agattattac    540

aggtcatgaa gaaggatatt tcacagctat aatgttgaag aaatcaagag tgaaattaaa    600

aagccaagag attattcctt ttccaagtac caaaatgatg agaaaccttt tatgtgtgca    660

tgtgaacgtg tcaggaaatg agctttgcct tatgacatcc catttggaga gcaccagagg    720

gcatgctgcg gaacgaatga atcagttaaa aatggtttta aagaaaatgc aagaggctcc    780

agagtcagct acagttatat ttgcaggaga tacaaatcta agggatcgag aggttaccag    840

atgtggtggt ttacccaaca acattgtgga tgtctgggag tttttgggca aacctaaaca    900

ttgccagtat acatgggata cacaaatgaa ctctaatctt ggaataactg ctgcttgtaa    960

acttcgtttt gatcgaatat ttttcagagc agcagcagaa gagggacaca ttattccccg   1020

aagtttggac cttcttggat tagaaaaact ggactgtggt agatttccta gtgatcactg   1080

gggtcttctg tgcaacttag atataatatt gtaaaatgct tttcaagtgt gggttttgcc   1140

ctgattgttg caaatacaat ttccaccttc tggaaaggta ggtttgctgt ggaggaaata   1200

atgtactaga tcattgtcac agaaaaacca actatgattt atggttgtgt tttcagaatt   1260

caacattaaa gattaatgtt tatttaaacg aacacattcc tgcattcagg atgtgaggcc   1320

atttaataaa aagggcacaa agcctgtcag agttttcaac ggtgcttata gctgccagct   1380

ggattccaaa caggtaccac attgtctctg agctaatgtt tatatttttc cattcaggca   1440

ccgaaatagt taatatttga aataagtctt caaaagaaaa cataagagat tattgagttc   1500

ttgggactgg atcctttatt tcataagttc agatcatctt aaatgaaaat gccatgatta   1560

tctgcagtta agtagatgac agctattcta catcagactt gatttttgtc agctaattac   1620

ataattggta agctataatt gaaaccttat ggcttaaaat tccttaactc ctttttgatt   1680

catgtttgta gtcatgttgt caacagaggc aaagttaagc ttgatgatgg ttaaaatcgg   1740

tttgatagca ccatgggaca tttttctaac aaaaataaat gcatgaagag acatagcctt   1800

ttagttttgc taattgtgaa atggaaatgc tttacaggaa gtaaatgcaa attactttta   1860

agtgtgcttt aaagaaaaat attttcccca caagagaaat ttaaataaag aattttattt   1920

gtttaaaaaa aaaaaaaaaa                                               1940


<210>  634
<211>  3998
<212>  DNA
<213>  Human

<400>  634
gctggcggct gtttccgggc ttagagggct ggagtggccg ccgagttgga ggcggtggtg     60

gcagcagtag gagtgtgtag agtgcgggat tgggggccag gccctgcgga gggcggggga    120

agttgtcttc ttttttttcc ggaggggccg gtaaacctgg tggctgaacg gcaagatgaa    180

tttcctccgc ggggtaatgg ggggtcagag tgccggaccc cagcacacag aagccgagac    240

gattcaaaag ctttgtgaca gagtagcttc atctacttta ttggatgatc gaagaaatgc    300

tgttcgtgct ctcaaatcat tatctaagaa ataccgcttg gaagtgggta tacaagctat    360

ggaacatctt attcatgttt tacaaacaga tcgttcagat tctgaaataa taggttatgc    420

tttggacata ctatataata taatatctaa tgaagaagaa gaagaagtag aagaaaattc    480

cacaagacag agtgaagatt tgggaagcca atttacagaa attttcatta agcagcagga    540

aaatgtcact cttctgttat ctttattgga ggagtttgat ttccatgtcc gctggcctgg    600

tgtgaagctt cttacttctc ttttaaaaca actagggcct caggtgcaac aaattatttt    660

agtcagtcct atgggtgttt caagattgat ggacttacta gcggattcca gggaagttat    720

acgtaatgat ggcgtcttac tactgcaggc actaacaaga agcaatggtg caatccagaa    780

aattgttgct tttgaaaatg ctttcgagag actactggac attatttcag aggaggggaa    840

cagtgatgga ggtatagtag ttgaagattg tttgattttg ctccaaaact tattaaaaaa    900

caacaactcc aatcaaaatt tttttaaaga aggctcatat attcaacgta tgaaaccttg    960

gtttgaagtt ggagatgaaa attctggctg gtctgcacag aaagtgacca atctacatct   1020

aatgctacag cttgttcgtg tattggtatc tcccaccaac cctcctggtg ctaccagtag   1080

ctgccagaag gctatgttcc agtgtgggtt attgcagcag ctttgtacta tcctaatggc   1140

tactggggtt cctgctgata tcctgactga gaccataaat actgtatcag aagttattcg   1200

aggctgccaa gtaaaccaag actactttgc atctgtaaat gcaccttcaa acccaccaag   1260

accggcaatt gtagtacttc tcatgtccat ggttaatgaa aggcagccat ttgttttgcg   1320

ctgtgctgtt ctctattgtt tccagtgttt cttgtataaa aaccaaaaag gacaaggaga   1380

aatcgtgtca acacttttac cttctaccat tgatgcaaca ggtaattcag tttcagctgg   1440

ccagttatta tgtggaggtt tgttttctac tgattcactt tcaaactggt gtgctgctgt   1500

ggcccttgcc catgcgttgc aagaaaatgc cacccagaaa gaacagttgc tcagggttca   1560

acttgctaca agtattggca accctccagt ttctttactt caacagtgca ccaatattct   1620

ttcacaggga agcaaaatac aaacaagagt tggattatta atgttgcttt gtacctggct   1680

aagcaattgt cccattgcag taacgcattt tcttcacaat tcagccaatg ttccatttct   1740

tacaggacaa attgcagaaa atcttggaga agaagagcag ttggtccaag gcttatgtgc   1800

ccttttgttg ggcatttcga tttatttcaa tgataactca cttgagagct acatgaaaga   1860

gaagctaaaa caactgattg agaagaggat tggcaaagag aatttcatag agaaactagg   1920

atttattagc aaacatgagt tgtattccag agcatctcag aaaccccagc caaactttcc   1980

cagtccagaa tacatgatat ttgatcatga gtttacgaag ctggtaaaag aacttgaagg   2040

tgttataact aaggctattt ataagtccag tgaagaagat aaaaaagaag aagaggtgaa   2100

aaaaacatta gaacagcatg acaatattgt gactcactac aaaaatatga ttcgagagca   2160

ggatctccaa cttgaggaat taaggcagca ggtttctaca ttaaaatgtc aaaatgaaca   2220

gctccagacg gcagtcacac agcaagtatc acagatccag cagcacaaag accagtataa   2280

tcttcttaaa atacagctag gaaaagacaa tcagcatcaa ggttcttaca gtgagggggc   2340

tcagatgaat ggcattcagc cagaagaaat tggtagattg cgagaagaga tagaagaatt   2400

aaaacgtaat caggaacttt tacaaagcca gctgactgaa aaggactcta tgattgaaaa   2460

tatgaaatct tcccaaacat ctggcacaaa tgaacagtct tcagcaatag tttcagctag   2520

agattctgaa caagttgcag aattaaaaca ggaactggca actttaaagt ctcagttaaa   2580

ctcacaatct gtggagatca ccaaactaca gacagaaaag caggaactgt tacagaaaac   2640

agaagcgttt gcaaaatcag ttgaggtaca aggagagacc gagactataa tagccaccaa   2700

aactactgat gtagaaggaa gactgtcagc attattacaa gagaccaaag agttaaagaa   2760

tgaaattaaa gctctgtctg aggaaagaac tgccattaaa gagcagctgg attcatctaa   2820

tagtaccatt gccattttac aaactgagaa agacaaacta gagttggaaa ttacagattc   2880

taaaaaagaa caagatgatc tcttggtgct cttggccgat caagatcaga aaatactgtc   2940

attgaagaat aaactcaagg atcttggtca tccagttgaa gaagaggatg aacttgaatc   3000

tggagaccaa gaggatgagg atgatgaaag tgaagatcct ggcaaggatc tagatcatat   3060

ctagttttca aatctctagg aacaatagag attatatcat aactctgaag atggactcta   3120

aactttggtt tacctccatg gaaaataaag atttagaaac caggtggaaa acattcacta   3180

ttaagactat tgatatattt ttgtaatgtt gccacccatg ttgaaaacct taaaactgaa   3240

tttatgtaga acacacatct tttatttaaa tccatctgaa ctgtcccaaa atgtaatttg   3300

caaagagctt caaacaccaa aaatatacca ttttaaggca tgtggtgaca atgctatttg   3360

ccttagttca ttcgttgttt actttgcaaa atttgtgact tttaagtact aacacatttg   3420

attgaatgtg tattgaattg gaattattat ttctaaattc agcatttgag tccttagttg   3480

atgattttct tttaaagaaa ttagtttatt taaaagcaag atagcctggg ttgggagtta   3540

gtgcatatca tcagccctcc atctaatgtg attgctaaga tgtgcaggat aggacagctt   3600

agaatgagtg ccttgacacc tacatatggc tgcattccat acctcagtga agaagccgaa   3660

ggatgctgac acacagtgat gtggagggca ttccggagaa acttttgcaa cagtgtatta   3720

atgtgattgg ttttcttttt gttttaagct aaacatctaa aacaaatttc aagttaacag   3780

ttcatacaac tcagatttag tattattgtt tatcataaaa catattatgt tcctagtttt   3840

aaaaagaccc aaagtatgat taatataatt tattggcatt tttgctgaat aggtttaagt   3900

cagataatag attttaaaaa agcaaatgag gcaatgtgtc aaaatttaat gtttcataat   3960

aaaaatagat acgttgactt aaaaaaaaaa aaaaaaaa                           3998


<210>  635
<211>  4575
<212>  DNA
<213>  Human

<400>  635
agcttggcgc tccgcctccc tcggccttag ctagaagtcg aaacaaaaca agccgctaag     60

gcggtggcgg cggcgccggg acgggggagg ggcgcgccgg aaccggaacc gacctgcgcc    120

ggaaccggaa cggagagcgg gttgccaggg cccgaagagg gctggctgcg gcggtctcgc    180

tcggctgtcc gttccttgct ggagaatttg gccacaaaga gttgccaaga tagctgggcc    240

aggaagaaag cgccgcagcc ctgacccaga cgctgttgcc gaccccgggg cactctggct    300

gtcgaccaag cggctcaaga tgtctggcgg ggccagtgcc acaggcccaa ggagagggcc    360

cccaggactg gaggacacca ctagtaagaa gaagcagaag gatcgagcaa accaggagag    420

caaggatgga gatcctagga aagagacagg gtctcgatat gttgcccagg ctggtcttga    480

acctctggcc tcaggtgatc cttctgcctc agcctcccat gcagctggga tcacaggctc    540

acgccaccgt acccggctgt tctttccttc atcgtcaggg tcagcatcca ctcctcaaga    600

ggagcagacc aaagagggag cttgtgaaga ccctcatgat ctcttggcta ctcccactcc    660

agagttgttg ctcgattgga ggcagagtgc agaagaggtg attgtcaagc ttcgtgtggg    720

agtaggtccc ctgcagctgg aggatgtaga tgctgctttc acagatacag actgtgtggt    780

gcggtttgca ggtggtcagc agtggggtgg tgtcttctat gctgagataa aaagctcttg    840

tgctaaagtg caaacccgca agggcagtct cctgcacctg acactgccca aaaaggtgcc    900

tatgctcacg tggccctccc tcctggttga ggctgatgaa cagctttgca taccaccgct    960

gaactcccaa acctgcctcc tgggctcaga ggagaattta gcccctttgg caggagagaa   1020

agcagtgcct cccgggaatg acccagtctc tccagccatg gtccggagca gaaaccctgg   1080

gaaagatgac tgtgccaagg aggagatggc agtggcagca gatgctgcaa ccttggtgga   1140

tgagcccgag tcgatggtga acctggcgtt tgtcaagaat gactcgtatg agaagggccc   1200

ggattcagtg gtggtgcacg tgtacgtgaa ggagatctgc agggacacct caagagtact   1260

tttccgtgag caggacttca cgctcatctt ccagaccagg gatggaaact tcctgaggct   1320

gcacccgggc tgtgggcccc acaccacctt ccgttggcag gtgaagctca ggaatctgat   1380

tgagccagag cagtgcacct tctgtttcac ggcttctcgc atcgacatct gccttcgtaa   1440

gaggcagagt cagcgctggg ggggcctgga ggccccggct gcacgagtgg gtggtgcaaa   1500

ggttgccgtg ccgacaggtc caacccctct ggattcaacc ccaccaggag gtgctcccca   1560

ccccctgaca ggccaggagg aggcccgggc tgtggagaag gataaatcca aggcacgatc   1620

tgaggacaca gggctagaca gtgtggcaac ccgcacaccc atggagcatg taaccccaaa   1680

gccagagaca cacctggcct cgcccaagcc tacatgcatg gtgcctccca tgccccacag   1740

cccagttagt ggagacagcg tggaggagga ggaagaggaa gagaagaagg tgtgtctgcc   1800

aggcttcact ggccttgtca atttaggcaa cacctgcttc atgaacagcg tcattcagtc   1860

tctgtccaac actcgggaac tccgggactt cttccatgac cgctcctttg aggctgagat   1920

caactacaac aacccactag ggactggtgg gcgtctggcc attggctttg ccgtgctgct   1980

tcgggcgctg tggaagggca cccaccatgc cttccagcct tccaagttga aggccattgt   2040

ggcgagtaag gccagccagt tcacaggcta tgcacagcat gatgcccagg agttcatggc   2100

tttcctgctg gatgggctgc acgaggacct gaatcgcatt cagaacaagc cctacacaga   2160

gaccgtggat tcagatgggc ggcccgatga ggtggtagct gaggaagcat ggcagcggca   2220

caagatgagg aatgactctt tcatcgtgga cctatttcag gggcagtaca agtcgaagct   2280

ggtgtgccct gtgtgtgcca aggtctccat cacttttgac ccgtttcttt atctgccggt   2340

gcccttgcca caaaagcaaa aggttctccc tgtcttttat tttgcccgag agccccacag   2400

caagcccatc aagttcctgg tgagcgtcag caaggagaac tccactgcga gcgaagtatt   2460

ggactccctc tctcagagtg ttcatgtgaa gcctgagaac ctgcgtttgg cggaggtaat   2520

taagaatcgt tttcatcgtg tgttcctacc ctcccactca ctggacactg tgtccccatc   2580

tgatacgctc ctctgctttg agctgctatc ctcagagttg gctaaggagc gggtagtggt   2640

gctagaggtg caacagcgcc cccaggtgcc cagcgtcccc atctccaagt gtgcagcctg   2700

ccagcggaag caacagtcgg aggatgaaaa gctgaagcgc tgtacccggt gctaccgtgt   2760

gggctactgc aaccagctct gccagaaaac ccactggcct gaccacaagg gcctctgccg   2820

acctgagaac attggctacc ccttcctggt cagtgtacct gcctcacgcc tcacttatgc   2880

ccgcctcgct cagttgctag agggctatgc ccggtactct gtgagtgtat tccagccacc   2940

ctttcagcca ggccgcatgg ccttggagtc tcagagccct ggctgcacca cactgctctc   3000

cacaggttcc ctggaggctg gggacagcga gagagacccc attcagccac ctgagctcca   3060

gctggtgacc cctatggctg agggggacac agggcttccc cgggtgtggg cagcccctga   3120

ccggggtcct gtgcccagca ccagtggaat ttcttctgag atgctggcca gtgggcccat   3180

tgaggttggc tccttgccag ctggcgagag ggtgtcccga cccgaagctg ctgtgcctgg   3240

gtaccagcat ccaagtgaag ctatgaatgc ccacacaccc cagttcttca tctataaaat   3300

tgattcatcc aaccgagagc agcggctaga ggacaaagga gacaccccac tggagctggg   3360

tgacgactgt agcctggctc tcgtctggcg gaacaatgag cgcttgcagg agtttgtgtt   3420

ggtagcctcc aaggagctgg aatgtgctga ggatccaggc tctgccggtg aggctgcccg   3480

ggccggccac ttcaccctgg accagtgcct caacctcttc acacggcctg aggtgctggc   3540

acccgaggag gcctggtact gcccacagtg caaacagcac cgtgaggcct ccaagcagct   3600

gttgctatgg cgcctgccaa atgttctcat cgtgcagctc aagcgcttct cctttcgtag   3660

ttttatctgg cgtgacaaga tcaatgactt ggtggagttc cctgttagga acctggacct   3720

gagcaagttc tgcattggtc agaaagagga gcagctgccc agctacgatc tatatgctgt   3780

catcaaccac tatggaggca tgattggtgg ccactacact gcctgtgcac gcctgcccaa   3840

tgatcgtagc agtcagcgca gtgacgtggg ctggcgcttg tttgatgaca gcacagtgac   3900

aacggtagac gagagccagg ttgtgacgcg ttatgcctat gtactcttct accgccggcg   3960

gaactctcct gtggagaggc cccccagggc aggtcactct gagcaccacc cagacctagg   4020

ccctgcagct gaggctgctg ccagccaggc ttcccggatt tggcaggagc tggaggctga   4080

ggaggagccg gtgcctgagg ggtctgggcc cctgggtccc tgggggcccc aagactgggt   4140

gggcccccta ccacgtggcc ctaccacacc agatgagggc tgcctccggt actttgtcct   4200

gggcaccgtg gcggctttgg tggccctcgt gctcaacgtg ttctatcctc tggtatccca   4260

gagtcgctgg agatgagctc gcctgcaggc agctgctgtg agctggccta cctgcctgcc   4320

ccaggccatg cctgcctttg ttgtggggaa cacctctggg ctttgggcct cagcttatgc   4380

atctggtggg agagggtggg gaggttgtgg cccctgcagg ggcagagtat cctagggtgt   4440

gtatccatct ggctgtctgt ccattcatcc tgctgctctg acccttggcc tcaggcttgg   4500

ccctgcccaa gctacttcct gtacttaaaa gtgttaataa aaccagacta ttcaggccca   4560

aaaaaaaaaa aaaaa                                                    4575


<210>  636
<211>  4968
<212>  DNA
<213>  Human

<400>  636
gcggccgccg tggccctcac agtcggcgtt tcgccgcctg cccgcggtgc ccgcgcacgc     60

cggccgccat cgccttcgcg cctggctggc gggggcgctg tcctcccagg ccgtccgcgc    120

cgctccctgg agctcggcgg agcgcggcag ccagggccgg cggaggcgcg aggagccggg    180

cgccaccgcc gccgccgccg ccgccgccgc gggggccatg accgtggagc agaacgtgct    240

gcagcagagc gcggcgcaga agcaccagca gacgtttttg aatcaactga gagaaattac    300

ggggattaat gacacccaga tactacagca agccttgaag gatagtaatg gaaacttgga    360

attagcagtg gctttcctta ctgcgaagaa tgctaagacc cctcagcagg aggagacaac    420

ttactaccaa acagcacttc ctggcaatga tagatacatc agtgtgggaa gccaagcaga    480

tacaaatgtg attgatctca ctggagatga taaagatgat cttcagagag caattgcctt    540

gagtttggcc gaatcaaaca gggcattcag ggagactgga ataactgatg aggaacaagc    600

cattagcaga gttcttgaag ccagcatagc agagaataaa gcatgtttga agaggacacc    660

tacagaagtt tggagggatt ctcgaaaccc ttatgataga aaaagacagg acaaagctcc    720

cgttgggcta aagaatgttg gcaatacttg ttggtttagt gctgttattc agtcattatt    780

taatcttttg gaatttagaa gattagttct gaattacaag cctccatcaa atgctcaaga    840

tttaccccga aaccaaaagg aacatcggaa tttgcctttt atgcgtgagc tgaggtatct    900

atttgcactt cttgttggta ccaaaaggaa gtatgttgat ccatcaagag cagttgaaat    960

tcttaaggat gctttcaaat caaatgactc acagcagcaa gatgtgagtg agtttacaca   1020

caaattatta gattggttag aagatgcctt ccaaatgaaa gctgaagagg agacggatga   1080

agagaagcca aagaacccca tggtagagtt gttctatggc agattcctgg ctgtgggagt   1140

acttgaaggt aaaaaatttg aaaacactga aatgtttggt cagtacccac ttcaggtcaa   1200

tgggttcaaa gatctgcatg agtgcctaga agctgcaatg attgaaggag aaattgagtc   1260

tttacattca gagaattcag gaaaatcagg ccaagagcat tggtttactg aattaccacc   1320

tgtgttaaca tttgaattgt caagatttga atttaatcag gcattgggaa gaccagaaaa   1380

aattcacaac aaattagaat ttccccaagt tttatatttg gacagataca tgcacagaaa   1440

cagagaaata acaagaatta agagggaaga gatcaagaga ctgaaagatt acctcacggt   1500

attacaacaa aggctagaaa gatatttaag ctatggttcc ggtcccaaac gattcccctt   1560

ggtagatgtt cttcagtatg cattggaatt tgcctcaagt aaacctgttt gcacttctcc   1620

tgttgacgat attgacgcta gttccccacc tagtggttcc ataccatcac agacattacc   1680

aagcacaaca gaacaacagg gagccctatc ttcagaactg ccaagcacat caccttcatc   1740

agttgctgcc atttcatcga gatcagtaat acacaaacca tttactcagt cccggatacc   1800

tccagatttg cccatgcatc cggcaccaag gcacataacg gaggaagaac tttctgtgct   1860

ggaaagttgt ttacatcgct ggaggacaga aatagaaaat gacaccagag atttgcagga   1920

aagcatatcc agaatccatc gaacaattga attaatgtac tctgacaaat ctatgataca   1980

agttccttat cgattacatg ccgttttagt tcacgaaggc caagctaatg ctgggcacta   2040

ctgggcatat atttttgatc atcgtgaaag cagatggatg aagtacaatg atattgctgt   2100

gacaaaatca tcatgggaag agctagtgag ggactctttt ggtggttata gaaatgccag   2160

tgcatactgt ttaatgtaca taaatgataa ggcacagttc ctaatacaag aggagtttaa   2220

taaagaaact gggcagcccc ttgttggtat agaaacatta ccaccggatt tgagagattt   2280

tgttgaggaa gacaaccaac gatttgaaaa agaactagaa gaatgggatg cacaacttgc   2340

ccagaaagct ttgcaggaaa agcttttagc gtctcagaaa ttgagagagt cagagacttc   2400

tgtgacaaca gcacaagcag caggagaccc agaatatcta gagcagccat caagaagtga   2460

tttctcaaag cacttgaaag aagaaactat tcaaataatt accaaggcat cacatgagca   2520

tgaagataaa agtcctgaaa cagttttgca gtcggcaatt aagttggaat atgcaaggtt   2580

ggttaagttg gcccaagaag acaccccacc agaaaccgat tatcgtttac atcatgtagt   2640

ggtctacttt atccagaacc aggcaccaaa gaaaattatt gagaaaacat tactagaaca   2700

atttggagat agaaatttga gttttgatga aaggtgtcac aacataatga aagttgctca   2760

agccaaactg gaaatgataa aacctgaaga agtaaacttg gaggaatatg aggagtggca   2820

tcaggattat aggaaattca gggaaacaac tatgtatctc ataattgggc tagaaaattt   2880

tcaaagagaa agttatatag attccttgct gttcctcatc tgtgcttatc agaataacaa   2940

agaactcttg tctaaaggct tatacagagg acatgatgaa gaattgatat cacattatag   3000

aagagaatgt ttgctaaaat taaatgagca agccgcagaa ctcttcgaat ctggagagga   3060

tcgagaagta aacaatggtt tgattatcat gaatgagttt attgtcccat ttttgccatt   3120

attactggtg gatgaaatgg aagaaaagga tatactagct gtagaagata tgagaaatcg   3180

atggtgttcc taccttggtc aagaaatgga accacacctc caagaaaagc tgacagattt   3240

tttgccaaaa ctgcttgatt gttctatgga gattaaaagt ttccatgagc caccgaagtt   3300

accttcatat tccacgcatg aactctgtga gcgatttgcc cgaatcatgt tgtccctcag   3360

tcgaactcct gctgatggaa gataaactgc acactttccc tgaacacact gtataaactc   3420

tttttagttc ttaacccttg ccttcctgtc acagggtttg cttgttgctg ctatagtttt   3480

taactttttt ttattttaat aactgcaaaa gacaaaatga ctatacagac tttagtcaga   3540

ctgcagacaa taaagctgaa aatcgcatgg cgctcagaca ttttaaccgg aactgatgta   3600

taatcacaaa tctaattgat tttattatgg caaaactatg cttttgccac cttcctgttg   3660

cagtattact ttgcttttat cttttctttc tcaacagctt tccattcagt ctggatcctt   3720

ccatgactac agccatttaa gtgttcagca ctgtgtacga tacataatat ttggtagctt   3780

gtaaatgaaa taaagaataa agttttattt atggctacct atgtgtttgt aagcaggtat   3840

attgtatatt agtgtattag taatactaga taaatgaatt ttgtctgggg attaagattg   3900

gatagttaat agattaatac aatcttttaa ttctgctcta atgctagcaa attggaaaat   3960

gtttaagtct ttgacactta aatttatcta tatttttaac aaagttcttg aacttagtat   4020

ggcaccggaa cctgttttga attcagtcag gtttttactc aagtaagtgg ttgatttttt   4080

ttaagtcaaa ctacactgaa acttttatcc ttttcttaga ttaatcttac tttttaaatg   4140

tatttacaat atacagcaag gtgattattt caagagaatc ccaaagtact tgaataaggg   4200

ctattgtaaa atttaaaaga aatatttata tatacacata tatacacata cacacatgta   4260

tatatatatt cttcataatg gaggacaatg ttttgcaata tataaatcat tctatttttg   4320

taaattgtat atcactttaa ttgaaaatgt tctctactaa ttaatactgt gaaacaaaat   4380

tgatgttgtt taactagaag ttatgagtat cttaactgcc tttattcctt ttcaaaaagg   4440

aaaaagctgt agaacatttt gtagatgaaa ctactgttta agattaatga attaatattg   4500

tgaatgaaaa tcaaaatcca tactttaaag gtaatcatgt tactaacaac ctatttttga   4560

attcataaaa atttctttat aaatgatgtt ttgtgaacat agtaaaatag accattatac   4620

tatgtgtatg tttgatacag cgtcgccaaa actagtgttc tttattagtg cctctcacaa   4680

aagatcctgg atggaggagt aagatgaaat attatgctat tatatgatgc tgtttgtaaa   4740

ggtattaatg tactagtaag gtgttaatga caaggaatta gtactattcc tgttgtaaag   4800

ttagattttg catattgtat ctatcaaaat atgtttgggt ttagatttta agttgtctac   4860

tgagcagatt tctgcattgg ttttccagtc ctgttaaaag tttagaaact tcatatgtgt   4920

catcacagct tttgtaaaga aagtatcctt aatattttat gacattct                4968


<210>  637
<211>  1137
<212>  DNA
<213>  Human

<400>  637
ggaagcggcg gcgggagctt ccgggagggc ggctcgcagg caccatgact cctgtgagga     60

tgcagcactc cctggcaggt cagacctatg ccgtgccctt catccagcca gacctgcggc    120

gagaggaggc cgtccagcag atggcggatg ccctgcagta cctgcagaag gtctctggag    180

acatcttcag cagctccatc ttgtctacaa gattttgtta gaagccgtca aaatcctgct    240

gactcgagat gcgctgtggt gcatgttttc cccgggcaca gcaggctaat aatcctgtta    300

caaagagaaa tgctgtacat ttcgagcagt gctggcccct gggactcacc gtggcctttt    360

ctaagtgctt acagactctc tgtttaataa tccattccag aaattttcca gggctcattg    420

ttgagcttgg tgttcgcaac tttgagtgat cagcccttct cctttgtggg agcaccagga    480

cagagcagcc tttgtccctc cccagtctca gttccctccc actgcccctg tggacctcga    540

atgcagagct tatgcaccta ccgaaggtcg tgtcagcacc caaggcagaa cgaggctgcc    600

ctgggaacta gggtcaatta agacagcttg tgctggagga ccctttacag cagatgaagg    660

cctctcccca gccagaaaag atggagcaca cgctgggtgg tggccccgct tcctcactgg    720

aaggagatgg tgctcttctt ttttctttct gaattgtggc caccttcata ccagtctgtc    780

atggaacact taagtcgctt gagtgcctgc tggtactccc agccctgcca tgcctgagcc    840

ccctgcacac aaggagccag gagtaatcag ggcagaccct ttagggcacg gggacttctg    900

gattgtgaaa ttggctctct gggggccaag gccttctaac gttggtggaa gtggctttgg    960

cttattgggt cggattctag gccattcatt ccaaccttta gagacatccc agctttccct   1020

agcccagagt ctgcagcccc tccaccatcc cacatcctcc ccctcccttt cctcatgaac   1080

cccagtcgcg cctctgcctt ctcaaacccc tccaccatcc cacaccctcc tcctgcc      1137


<210>  638
<211>  5396
<212>  DNA
<213>  Human

<400>  638
gccgccgcca gggaaaagaa agggaggaag gaaggaacaa gaaaaggaaa taaagagaaa     60

ggggaggcgg ggaaaggcaa cgagctgtcc ggcctccgtc aagggagttg gagggaaaaa    120

gttctcaggc gccgcaggtc cgagtgcctc gcagcccctc ccgaggcgca gccgccagac    180

cagtggagcc ggggcgcagg gcgggggcgg aggcgccggg gcgggggatg cggggccgcg    240

gcgcagcccc ccggccctga gagcgaggac agcgccgccc ggcccgcagc cgtcgccgct    300

tctccacctc ggcccgtgga gccggggcgt ccgggcgtag ccctcgctcg cctgggtcag    360

ggggtgcgcg tcgggggagg cagaagccat ggatcccggg cagcagccgc cgcctcaacc    420

ggccccccag ggccaagggc agccgccttc gcagcccccg caggggcagg gcccgccgtc    480

cggacccggg caaccggcac ccgcggcgac ccaggcggcg ccgcaggcac cccccgccgg    540

gcatcagatc gtgcacgtcc gcggggactc ggagaccgac ctggaggcgc tcttcaacgc    600

cgtcatgaac cccaagacgg ccaacgtgcc ccagaccgtg cccatgaggc tccggaagct    660

gcccgactcc ttcttcaagc cgccggagcc caaatcccac tcccgacagg ccagtactga    720

tgcaggcact gcaggagccc tgactccaca gcatgttcga gctcattcct ctccagcttc    780

tctgcagttg ggagctgttt ctcctgggac actgaccccc actggagtag tctctggccc    840

agcagctaca cccacagctc agcatcttcg acagtcttct tttgagatac ctgatgatgt    900

acctctgcca gcaggttggg agatggcaaa gacatcttct ggtcagagat acttcttaaa    960

tcacatcgat cagacaacaa catggcagga ccccaggaag gccatgctgt cccagatgaa   1020

cgtcacagcc cccaccagtc caccagtgca gcagaatatg atgaactcgg cttcaggtcc   1080

tcttcctgat ggatgggaac aagccatgac tcaggatgga gaaatttact atataaacca   1140

taagaacaag accacctctt ggctagaccc aaggcttgac cctcgttttg ccatgaacca   1200

gagaatcagt cagagtgctc cagtgaaaca gccaccaccc ctggctcccc agagcccaca   1260

gggaggcgtc atgggtggca gcaactccaa ccagcagcaa cagatgcgac tgcagcaact   1320

gcagatggag aaggagaggc tgcggctgaa acagcaagaa ctgcttcggc aggcaatgcg   1380

gaatatcaat cccagcacag caaattctcc aaaatgtcag gagttagccc tgcgtagcca   1440

gttaccaaca ctggagcagg atggtgggac tcaaaatcca gtgtcttctc ccgggatgtc   1500

tcaggaattg agaacaatga cgaccaatag ctcagatcct ttccttaaca gtggcaccta   1560

tcactctcga gatgagagta cagacagtgg actaagcatg agcagctaca gtgtccctcg   1620

aaccccagat gacttcctga acagtgtgga tgagatggat acaggtgata ctatcaacca   1680

aagcaccctg ccctcacagc agaaccgttt cccagactac cttgaagcca ttcctgggac   1740

aaatgtggac cttggaacac tggaaggaga tggaatgaac atagaaggag aggagctgat   1800

gccaagtctg caggaagctt tgagttctga catccttaat gacatggagt ctgttttggc   1860

tgccaccaag ctagataaag aaagctttct tacatggtta tagagccctc aggcagactg   1920

aattctaaat ctgtgaagga tctaaggaga cacatgcacc ggaaatttcc ataagccagt   1980

tgcagttttc aggctaatac agaaaaagat gaacaaacgt ccagcaagat actttaatcc   2040

tctattttgc tcttccttgt ccattgctgc tgttaatgta ttgctgacct ctttcacagt   2100

tggctctaaa gaatcaaaag aaaaaaactt tttatttctt ttgctattaa aactactgtt   2160

cattttgggg gctgggggaa gtgagcctgt ttggatgatg gatgccattc cttttgccca   2220

gttaaatgtt caccaatcat tttaactaaa tactcagact tagaagtcag atgcttcatg   2280

tcacagcatt tagtttgttc aacagttgtt tcttcagctt cctttgtcca gtggaaaaac   2340

atgatttact ggtctgacaa gccaaaaatg ttatatctga tattaaatac ttaatgctga   2400

tttgaagaga tagctgaaac caaggctgaa gactgtttta ctttcagtat tttcttttcc   2460

tcctagtgct atcattagtc acataatgac cttgatttta ttttaggagc ttataaggca   2520

tgagacaatt tccatataaa tatattaatt attgccacat actctaatat agattttggt   2580

ggataatttt gtgggtgtgc attttgttct gttttgttgg gttttttgtt ttttttgttt   2640

ttggcagggt cggtgggggg gttggttggt tggttggttt tgtcggaacc taggcaaatg   2700

accatattag tgaatctgtt aatagttgta gcttgggatg gttattgtag ttgttttggt   2760

aaaatcttca tttcctggtt ttttttacca ccttatttaa atctcgatta tctgctctct   2820

cttttatata catacacaca cccaaacata acatttataa tagtgtggta gtggaatgta   2880

tcctttttta ggtttccctg ctttccagtt aatttttaaa atggtagcgc tttgtatgca   2940

tttagaatac atgactagta gtttatattt cactggtagt ttaaatctgg ttggggcagt   3000

ctgcagatgt ttgaagtagt ttagtgttct agaaagagct attactgtgg atagtgccta   3060

ggggagtgct ccacgccctc tgggcatacg gtagatatta tctgatgaat tggaaaggag   3120

caaaccagaa atggctttat tttctccctt ggactaattt ttaagtctcg attggaattc   3180

agtgagtagg ttcataatgt gcatgacaga aataagcttt atagtggttt accttcattt   3240

agctttggaa gttttctttg ccttagtttt ggaagtaaat tctagtttgt agttctcatt   3300

tgtaatgaac acattaacga ctagattaaa atattgcctt caagattgtt cttacttaca   3360

agacttgctc ctacttctat gctgaaaatt gaccctggat agaatactat aaggttttga   3420

gttagctgga aaagtgatca gattaataaa tgtatattgg tagttgaatt tagcaaagaa   3480

atagagataa tcatgattat acctttattt ttacaggaag agatgatgta actagagtat   3540

gtgtctacag gagtaataat ggtttccaaa gagtattttt taaaggaaca aaacgagcat   3600

gaattaactc ttcaatataa gctatgaagt aatagttggt tgtgaattaa agtggcacca   3660

gctagcacct ctgtgtttta agggtctttc aatgtttcta gaataagccc ttattttcaa   3720

gggttcataa caggcataaa atctcttctc ctggcaaaag ctgctatgaa aagcctcagc   3780

ttgggaagat agattttttt ccccccaatt acaaaatcta agtattttgg cccttcaatt   3840

tggaggaggg caaaagttgg aagtaagaag ttttatttta agtactttca gtgctcaaaa   3900

aaatgcaatc actgtgttgt atataatagt tcataggttg atcactcata ataattgact   3960

ctaaggcttt tattaagaaa acagcagaaa gattaaatct tgaattaagt ctggggggaa   4020

atggccactg cagatggagt tttagagtag taatgaaatt ctacctagaa tgcaaaattg   4080

ggtatatgaa ttacatagca tgttgttggg atttttttta atgtgcagaa gatcaaagct   4140

acttggaagg agtgcctata atttgccagt agccacagat taagattata tcttatatat   4200

cagcagatta gctttagctt agggggaggg tgggaaagtt tggggggggg gttgtgaaga   4260

tttaggggga ccttgataga gaactttata aacttctttc tctttaataa agacttgtct   4320

tacaccgtgc tgccattaaa ggcagctgtt ctagagtttc agtcacctaa gtacacccac   4380

aaaacaatat gaatatggag atcttccttt acccctcaac tttaatttgc ccagttatac   4440

ctcagtgttg tagcagtact gtgatacctg gcacagtgct ttgatcttac gatgccctct   4500

gtactgacct gaaggagacc taagagtcct ttcccttttt gagtttgaat catagccttg   4560

atgtggtctc ttgttttatg tccttgttcc taatgtaaaa gtgcttaact gcttcttggt   4620

tgtattgggt agcattggga taagatttta actgggtatt cttgaattgc ttttacaata   4680

aaccaatttt ataatcttta aatttatcaa ctttttacat ttgtgttatt ttcagtcagg   4740

gcttcttaga tctacttatg gttgatggag cacattgatt tggagtttca gatcttccaa   4800

agcactattt gttgtaataa cttttctaaa tgtagtgcct ttaaaggaaa aatgaacaca   4860

gggaagtgac tttgctacaa ataatgttgc tgtgttaagt attcatatta aatacatgcc   4920

ttctatatgg aacatggcag aaagactgaa aaataacagt aattaattgt gtaattcaga   4980

attcatacca atcagtgttg aaactcaaac attgcaaaag tgggtggcaa tattcagtgc   5040

ttaacacttt tctagcgttg gtacatctga gaaatgagtg ctcaggtgga ttttatcctc   5100

gcaagcatgt tgttataaga attgtgggtg tgcctatcat aacaattgtt ttctgtatct   5160

tgaaaaagta ttctccacat tttaaatgtt ttatattaga gaattcttta atgcacactt   5220

gtcaaatata tatatatagt accaatgtta cctttttatt ttttgtttta gatgtaagag   5280

catgctcata tgttaggtac ttacataaat tgttacatta ttttttctta tgtaatacct   5340

ttttgtttgt ttatgtggtt caaatatatt ctttccttaa actcttaaaa aaaaaa       5396


<210>  639
<211>  7333
<212>  DNA
<213>  Human

<400>  639
agaaatccag cccttctgcc ctccggaggc gcctttccca acgtaaagta caattttaaa     60

tttcagctcc tgactaaaat catgatccgc agtcaactgc tagagaatct gggcaccccg    120

gtgtctctgg agcgtgcagc gagtgtgggc aagggcaggg ggagtgggcg aagctgctgg    180

ttggtgcctg aaatctgtgc gttgcccctt taattgtgtc cccagccctc gggcgtttct    240

gtccaacgcc cacgtcagca aatacctttt gtttctctca cgttggggct acttgtttta    300

gggcgcaaag gaacggcctc gaaagggggt ccttccccag ccgagaacca ggaatcttcc    360

ctcggcccgc gcgcgcgacc ggccggtgcg ccgcggcccg cggacaatcc tccaaacaca    420

gactgtttga cttagaatct tccctttttt actccattca agagcagcat tcataaattt    480

ccagaatgga gatctcctct catcagtctc acctcctgca gcaactgaac gagcagcgca    540

ggcaagatgt attttgtgac tgcagtattc tagttgaagg gaaggtcttc aaagcacatc    600

gaaatgtatt attcgctagt agcggctact ttaaaatgct tctttctcag aattcaaagg    660

agacgagtca gccaaccaca gctacatttc aggctttctc ccctgacact tttacagtta    720

tcttggactt cgtatattct ggcaaactgt ctcttactgg tcagaatgtc atagaagtga    780

tgtcggctgc tagcttcctt cagatgactg atgtcataag tgtatgtaag acttttatta    840

aatcttcctt agacattagt gagaaagaaa aagatcgcta tttcagtctc tcagataaag    900

atgccaattc taatggtgta gaacgttcct ctttttatag tggtggctgg caagaaggaa    960

gcagttctcc acgttctcac ctaagcccag agcaaggaac aggtataata agtggaaaat   1020

cttggaataa gtataattat catccagcct cccagaagaa tactcaacaa cccttggcca   1080

agcatgaacc aaggaaagag tccattaaaa agaccaaaca tttgagattg tcacagcctt   1140

ctgaagttac tcattataag tcaagcaaac gagaagtacg aacatctgat tcttccagcc   1200

atgtttccca gtctgaagaa caagcacaga ttgatgctga aatggactct actcctgttg   1260

gctatcagta cggtcaagga tctgatgtca catccaaaag ctttccagat gatctgcctc   1320

ggatgcgatt caagtgcccg tactgcacac atgtggtgaa gcggaaggca gacctaaagc   1380

gccaccttcg ttgtcataca ggagaaaggc cctatccatg tcaagcttgt ggaaaaagat   1440

ttagcaggct agaccatcta agtagccatt ttcgaacaat tcaccaggca tgtaaactca   1500

tctgcagaaa atgtaaacgt catgtgacag atctaacagg gcaagtggta caggagggaa   1560

ccaggcgcta cagactgtgt aatgagtgtc ttgcagaatt tggcatagac agcctcccca   1620

ttgacttgga agctgaacaa catcttatgt ccccatcaga tggagataag gattccagat   1680

ggcacttgag tgaagatgag aatagatcct atgtggagat tgtagaagat gggtctggtg   1740

atctggtcat ccaacaggtt gatgatagtg aagaagaaga agaaaaagaa attaagccca   1800

acattaggta gctgtaatgt gaaccaacag agctggcatg tctgcaattt acattgactt   1860

cctgtatctc tctctttcta tggtcggagt ctagttaaca aatttatcac actgacttta   1920

aagaaatgat ctgatataac ttgcatgctt tctgaacagg ccattgtatc cattctgaac   1980

tttgttgccc taaaatgtgt tgctgcactg gaaagaaaga actagcttga gttggcttga   2040

tggatgaaca attatcctct tactttcatt acaatcctct tactttattc cagagatacc   2100

tttttctttt aatattggag gatctactta gcaaactttt ttcaaagaaa atactttaaa   2160

taaattcacc acaaccaaac tttatgtaag acaatttcaa ggtgtttcaa aaacacataa   2220

ctaccaatgt ttaatttcac agggaaccag ttaagagcac atttaaggat ctggcaaccc   2280

accttactaa acaaattagt ctttctatta atttgagatc tgaaacaacc tgtcattact   2340

ctgatatcct gaacgtttaa ggattatgga agaagactaa agtgtttgaa atcattcata   2400

tttgaaattt ttatcattag cttaaaaatt actctcagta ttgttaaaaa aaaaaaaaag   2460

tagaggctgg ccaaagatta tatacagata ttttcttaaa gcaggaaact aatgttgcct   2520

aaaagtcaag gtagtttgtg aagacaatct gtcaatatgg ttgtccatct ctctaaagaa   2580

aagcaggctg ggcgctgtgg ctcatgccta taatcccaat actttgggag gccgaggcag   2640

gcggatcaca aggtcaggag tttgaaacca gcctggccaa catggtgaaa cctcgtctct   2700

actaaaaaat acaaaattag ccgggcatgg tggcgggtgc ctataatccc agctactcgg   2760

gaggctgagg caggagaatc gattgaacct ggaaggcaga agttgcagtg agccgagatc   2820

acaccattgc actccagcct gggcaacaag agcgaaactc cgtctcaaaa aaaaaaggaa   2880

aacaaactag gaggttctta ccatatgtga gtgatttcta acgtttatgt agtgctatat   2940

tatttataaa gtactctctc atgtattttc tcagtgaggt ggatactatc tccgatttac   3000

aaatgaggaa attaaggtca gaaagtctga gagagaaaac tgatgattgg acaggatctg   3060

attttaaaca atcctctttc agccttctct ccctgtatgt ctcctgaaat ggcaaagaat   3120

agaagtcaaa cctcaccagt tggcagtcat tataaaaata agccaatcag aattagaaag   3180

tatgaaagga ggaattgaat cattttcaac aacatacaat atcttgatct agagattttc   3240

aaataatgct aagtaatgtc cctacagtac ctattggtat gtttttatgt cacgttattt   3300

atatgtaaat ttaaagtata aaactatttg aacaaattat tcacttaaat atgttgaaca   3360

tttttgcttc tcttgtttat ataatatttt caaaacaaac ttttctccta gtatacaaag   3420

tttaaacttc tcccctttgg gctgggccca gtggctcacg cctgtaatcc cagcactttg   3480

ggaggctgag gcaggtggat caccgaggtc gggagtttga gaccagcctg accaacatgg   3540

agaaaccccg tctctactaa aaatacaaaa ttagccgggc gtggtggtgc atgcctgtaa   3600

tcccagctac tcagaaggct gaggcaggag gatagcttga acccaggagg cagaggctgc   3660

ggtgggctga ggttgcgcca ttgcactcca gcctgggcaa caagagcgaa actccgtctc   3720

aaaaaaaaaa aaaaaaaaaa cttctcccct gcataaatta tgaaacattc caaaattaca   3780

gctaaattag agaagcattg tttcagttct aaaggtaaaa tctaaatatc cgaagtaaag   3840

aactgagctt cataaaggtc tcttctgcaa gttatcacag tgaagcttga tagaatttca   3900

ctgtatatgg agaggctcca tctattttac tgttttcttt tttgtttttg tttttttttc   3960

gagacggagt ctcgctctgt cgcccaggct ggagtgcagt ggtgcaatct cagctcactg   4020

caagctccac ctcccgggtt ctcgccattc tcctgcctca gcctcccgag tagctgggac   4080

ttacaggcgc ccaccaccac tcccagctaa ttttttgtat ttttaataga gatggggttt   4140

caccgtgtta gccaggatgg tctcaatctc ctgatctcgt gatccgcccc cctcggcctc   4200

ccaaagtgct gggattacag gcgtgagcca ctgcgcccag ccaattttac tgtattttta   4260

aatgccatga catacctcaa aattatcctt tttatgttac tattttctct tgttctttca   4320

ttaattattg tccttgatac caatttctag gctaaattgg ttactttctt ttaaaaaatt   4380

taaaaataga tgaataacca cttgtttcat ggtacttaat tgagactttt tcaagattcc   4440

cctgatggca catttgcagt tgcttcaaga ctggatgatg tgcattgagt tctctgttct   4500

cccaacatgg ctgttcctaa atcaggattc tggttttttt gagatggact ctcgctctgt   4560

tgtccaagct ggagtgcagt ggcgtgatct cgctcaccac aacctctgcc tcccgggttc   4620

aagcgattct cctgcctcag cctcctgagt agccgggact acaggcatgt gccaccatgc   4680

ctggctaatt tttgtatttt tagtagagac agggtttcgc tatgttggcc aggctggtct   4740

cgaactcctg acctcgtgat ctgcccgcct cagcctccca aagtgctggg attacaggcg   4800

tgagccagca cgcccggcct aaatcaggat tcttaacaat taaagtgtat ctgaatgagg   4860

aaggaaacgc ttgtcattct ctagtcttac ccaattaata ctgacacctt ttgaaattaa   4920

aacctgattt tttagttgtt ggagccagta ggaaaaatgg ctgatttgaa cttttttcct   4980

ataaatgaag tagtgcttgc atgtgtgtac tctaatgcac tttagtctat gatctaaatg   5040

tccttttatg ctattatctt ctgcatgcaa actttacata catcagcatg aatatccaac   5100

attcactgaa cacagtgcca ccagcacttg taattgcctt ttcagaaata atgctttctc   5160

ataattgttt ataacgagca tcaaactatc cccacaaaat gatcaagttc accaaactag   5220

acaaagaatc tgttgtatca ttttaacatc atagaagaac atttaagaca tgtttgtaag   5280

ttgtaaataa tgactccagt tatagcatat atatctaaga cgttagagac cagttatttt   5340

ctagagtgaa actgtctatt gatgattgag aaaattgaat tctttggttt ttacatgtgg   5400

gcaaatgtta cataggggta taatctgttt aaataagctt tatttatgcc aaggattttt   5460

tttttaatat caagacttgg ttagaccaaa gtttgctctt gcaggaatgc catttatcag   5520

cttctgaatg cccttctaac tccattaccc tcaagagtgt ctgggtatag gatgaagcat   5580

tacaaaaaga aagcaccact gcagtcatgc ctagtgtctg ggagaaacaa aatggactag   5640

acctgcagtt taaaataatt taacccgaga aactcttcaa atgaattgtt tcctaaagat   5700

gctcaaattt aagggataaa ctctaaaatc agagctgctg tggttaaagt cccccacaaa   5760

cctttcccca gacacctctg cagaactcag gtgcacaatg ttgaaaacca tggaattaga   5820

caacttcctg aattcccttt gagccttgca gcctcatttc gttactcctg ttactcacgg   5880

tgcttataag caggtaacca tatggtctct tagtgaagca aatcacatcc ttagcacatg   5940

atgttccttc tatgggtatc agatcttaag actttttaaa atttaggaac aaatgtttca   6000

atattatatt ttcagtaatg caatcaaaat aagcatagtt actgttttct gtacggctaa   6060

gtactgccta atggatgaaa gaagtttggt gcttcaatta tttatgagct cagaactcaa   6120

ttcattaaag ttattttgcc aagtcatgcc aagatatatt gaaatttcca ctcatattgg   6180

tttttaaaat tttttttagt cctaaaatta ataagtatgg aaaatcacta aaagcagtgt   6240

aggataaggt gtgtttaact ggccgggcac ggtggctcat gcctgtaatc ctagcacttt   6300

gggaggccga ggcgggcgga tcacttaagg ccaggtgttc gagaccatcc tggccaacat   6360

ggtgaaaccc cgtctctagt aaaaatacaa aaaatagctg ggcatgatgg tgggtgcctg   6420

taatcccagg tactcgggag gctgaggcag gagaatcgct tgaacccggg aggtggaggt   6480

tgcagtggcc gagatcgcac cactgcactc cagcctgggt gacagagcga gactccatca   6540

aaaaaaaaaa aaaaaaaaaa aaagatgtgt ttaactggga agggtgataa taatagaata   6600

ataggtacag gaggaccaaa ctttagatta taaaccagaa agttttgtta ttttatataa   6660

gtgtatcagt attactattt atcatttata tagcatttta tatttgcaaa gtgtttaata   6720

atttttgtta ttctttacat atatatgaaa taggacagtt atcccacatg aacggtaaat   6780

aaattgaggc acagaacagt aaaaaaacct cagggtcagg cgtggtggct cacacctgta   6840

atcccagcac tttgggaggc caaggcgggt ggatcacttt aggtcaagag ttggagacca   6900

gcctggggca atatagtgaa accccttctc tactaaaaat acaaaaatta gccaggcatg   6960

gtggtgggca cctgtaatcc cagctactct gggggctgag acaggagaat tgcttgaact   7020

caggaggcgg aggttgcagt gagccaagat cacgctactg cactccaggc tgggtgacag   7080

agcgagactc cacctcaaaa aaaaaaaaaa aaaaaaaaaa aagaacctaa gacaacccag   7140

tgaaatggta gcaaaaaata ggaaatataa tgatcacatt ttctgaatcc tagaccatca   7200

gcctaattca ctgaggtgtg ttgtgtatca ctctatttta tagatgattt tatataagta   7260

acagtggatt gttttaaagc tgacgtcatt gtatgtggat acattctata tggaataaat   7320

gttatgtaaa gga                                                      7333


<210>  640
<211>  2080
<212>  DNA
<213>  Human

<400>  640
agttgtagtt cggggtgagg ccggggcttc atggggagtt gttgggctga acgagcggct     60

cggagtatgg gattggggga gggggacggg ggagtttggc gcaaagcctg ctggggcatg    120

gagtcccggc gagctttgtg cgcatgtgcg gggaggtgag ggggcttggg gggcctcgcc    180

tgagagagtg aggacaggct gcgggaggag ctgcaggact gaggtacaga ggccaggggc    240

ccagggcagg acccagcctg gacttgactc cctgggatcc caggaagggc acaccctttc    300

ctcaccaccc gagtgagcgc tgccccctca cagagacctc tttgccccct gggccaggca    360

gagcaggcgc tgcggtccgg gaggccccat ggaggtggcg gtgcccgtga agcaggaggc    420

cgagggcctg gcgctggact ccccgtggca ccgcttccgc cgcttccacc tgggcgacgc    480

gccgggcccg cgggaggcgc tggggctgct ccgcgccctg tgccgggact ggctgcggcc    540

cgaggtgcac accaaggagc agatgttgga gctgctggtg ctggaacagt tcctgagcgc    600

gctgcccgcc gacacgcagg cctgggtgtg cagccggcag ccgcagagcg gggaggaggc    660

ggtggccctg ctggaggagc tctgggggcc agcagcctcc cccgatgggt cgtcagcaac    720

gagggtgcct caggatgtga cgcagggccc tggggccaca ggtggaaagg aggacagtgg    780

gatgattccc ttagcaggca ccgcccctgg ggctgagggg ccggcgcctg gggactccca    840

ggctgtgcgc ccctacaagc aggagcccag cagccccccg ctggcgcctg gcctgcccgc    900

cttcctagcg gccccgggca ccacgtcctg ccccgagtgc ggcaaaacgt ccctgaaacc    960

agctcacctg ctgcgccacc ggcagagcca ctcgggcgag aagccgcacg cctgccctga   1020

gtgcgggaag gcctttcggc gcaaggagca cctgcggcgc caccgcgaca cgcaccccgg   1080

cagccccggc agccccgggc ccgcgctgcg ccctctgccc gcccgtgaga agccccacgc   1140

gtgctgcgag tgtggcaaga ccttctactg gcgcgagcac ctggtgcgcc accgcaagac   1200

gcactcggga gcgcggccct ttgcctgctg ggagtgtggc aagggcttcg ggcgccgcga   1260

gcacgtgctg cgccaccagc gcatccacgg ccgggcagcg gccagcgcgc agggggcggt   1320

agctccgggc ccggatggtg gaggcccctt cccgccctgg cccttgggtt agccgcctcc   1380

cggccagcgc catctcccgc ccttggtgct gcccccgggc ggtacctgct ctctcccagc   1440

gccacttggc ctcttcctct cctccttccc tcccatcgtc ctcctccacc tgcgcctccc   1500

ttgtctgaac ttcccaacgc cttcctattc ctttccaact ccttttcccc caaatttcac   1560

tttccttctc aggtctcacc tcagcccccc ccttctccct gatttctcgg cctctctctc   1620

tgtgtgaagg ggcctctccc taatgtctcc tccttccccc ctcttctctc tcctgcggcc   1680

cagcctccct ctccctcctc cattcctctc tccctgccct tttcctgcct gaagagcaga   1740

ggtgaggacc tgggacccct gaggggcagg ccaggaggag ctcgggcgca ggccaggccc   1800

ccttggtgaa gcagaggctg aaggaaaggg gtctgggtct tgtccctagg aattctcctc   1860

cctcaggaga ttgggggttg ggggaggcag cgggtgatgg ctctgaagct gaacccaggg   1920

cctggctgtg gtcttcttgg tcttgctgcc ccctgtgacc caaaggcatg ggatggacag   1980

agatgcctgc ccccgtgaag ctggttgggg agggcagttc accagcatcc atagagtaat   2040

aaagtcactg tgtgtagacc cggaaaaaaa aaaaaaaaaa                         2080


<210>  641
<211>  5069
<212>  DNA
<213>  Human

<400>  641
ttcctgtctg ccctccgcgg gctccggctg ccatggagga ggaagaggag gcgataggct     60

tgctggacaa ggttctggag gacgaagatg tgtttctcct ggaggagtgc gagctgggaa    120

ccccgaccag ccccggctca gggtccccct tcctggtggc tgtgaaggtg gaagcaggga    180

aaggcctgga gatgaggaag ctggttctct cggggttctt ggccagcgaa gagatctaca    240

ttaaccagct ggaagccctg ttgctgccca tgaaacccct gaaggccacc gccaccacct    300

cccagcccgt gctcaccatc cagcagatcg agaccatctt ctacaagatc caggacatct    360

atgagatcca caaggagttc tatgacaacc tgtgccccaa ggtgcaacag tgggacagcc    420

aggtcaccat gggccacctc ttccagaagc tggccagcca gctcggtgtg tacaaagcgt    480

ttgtcgataa ctataaagtc gctctggaga cagctgagaa gtgcagccag tccaacaacc    540

agttccagaa gatctcagag gaactcaaag tgaaaggtcc caaggactcc aaggacagcc    600

acacgtctgt caccatggaa gctctgctct acaagcccat tgaccgggtc actcggagca    660

ccctagtcct acacgacctg ctgaagcaca cacctgtgga ccaccccgac tacccgctgc    720

tgcaggatgc cctccgcatc tcccagaact tcctgtccag catcaacgag gacatcgacc    780

cccgccggac tgcagtgaca acgcccaagg gggagacgcg acagctggtg aaggacggct    840

tcctggtgga agtgtcagag agctcccgga agctgcggca cgtcttcctc tttacagatg    900

tcctactgtg tgccaagctg aagaagacct ctgcagggaa gcaccagcag tatgactgta    960

agtggtacat ccccctggcc gacctggtgt ttccatcccc cgaggagtct gaggccagcc   1020

cccaggtgca ccccttccca gaccatgagc tggaggacat gaagatgaag atctctgccc   1080

tcaagagtga aatccagaag gagaaagcca acaaaggcca gagccgggcc atcgagcgcc   1140

tgaagaagaa gatgtttgag aatgagttcc tgctgctgct caactccccc acaatcccgt   1200

tcaggatcca caatcggaat ggaaagagtt acctgttcct actgtcctcg gactacgaga   1260

ggtcagagtg gagagaagca attcagaaac tacagaagaa ggatctccag gcctttgtcc   1320

tgagctcagt ggagctccag gtgctcacag gatcctgttt caagcttagg actgtacaca   1380

acattcctgt caccagcaat aaagacgacg atgagtctcc aggactctat ggcttccttc   1440

atgtcatcgt ccactctgcc aagggattta agcaatcagc caacctgtac tgtaccctgg   1500

aggtggattc cttcggctat tttgtcagca aagccaaaac cagggtgttc cgggacacag   1560

cggagcccaa gtgggatgag gagtttgaga tcgagctgga gggctcccag tccctgagga   1620

tcctgtgcta tgagaagtgc tatgacaaga ccaaggtcaa caaggacaac aatgagatcg   1680

tggacaagat catgggcaaa ggacagatcc agctggaccc acaaaccgtg gagaccaaga   1740

actggcacac ggacgtgatt gagatgaacg ggatcaaagt ggaattttcc atgaaattca   1800

ccagccgaga tatgagcctg aagaggaccc cgtccaaaaa gcagaccggc gtcttcggtg   1860

tgaagatcag cgtggtgacg aagcgggagc gctccaaggt gccctacatc gtccggcagt   1920

gtgtggagga ggtggagaag aggggtatcg aggaggttgg catctacagg atatcgggcg   1980

tggccacgga catccaggcg ctcaaggccg tcttcgatgc caataacaag gacatcctgc   2040

tgatgctgag tgacatggac atcaacgcca tcgccgggac gctcaagctg tacttccggg   2100

aactgcccga gccgctcctc acggaccgac tctacccagc cttcatggag ggcatcgccc   2160

tgtcagaccc tgctgccaag gaaaactgca tgatgcacct gctccgctcc ctgcccgacc   2220

ccaacctcat caccttcctc ttcctgctgg aacacttgaa aagggttgcc gagaaggagc   2280

ccatcaacaa aatgtcactt cacaacctgg ctaccgtgtt tggacccacg ttactgagac   2340

cctcagaagt ggagagcaaa gcacacctca cctcggctgc ggacatctgg tcccatgacg   2400

tcatggcgca ggtccaggtc ctcctctact acctgcagca cccccccatt tccttcgcag   2460

aactcaagcg gaacacactg tacttctcca ccgacgtgta gcccgaggca gggtggctgc   2520

gggcgggtgg tggaaccagc ccctccagcc tggggtccaa ctcagacttg aaagactgca   2580

atagaaaact cccaaaccca gcactccaga ctcgagggaa gccagcttcc aagaactgga   2640

atgcgtacgt cttttgtgcc accttgtaca aagccggctg cccagcccca gcctcaccac   2700

cgcatcccac ctcctgccct ccatacctct agttgtgtct gatgctccgt gctgttcggg   2760

aattgtttta tgtacacttg tcaggcagaa aaggtagtga ccggcccggc gtgggcacac   2820

agacagcccg ctttgttctt tcatttcctc cagcactttc tttccgcctg agtccagccc   2880

aaggcctttt attttgcgct gtgtaactgc tgccagcttc tctcttggcc ctgctcccag   2940

atggcggtct cctggcagcc tcccctcagt cttcctccac ccgctcttcc ttcccagcct   3000

gcctgcatgc atgtgcaccc ttggtcttcg ctccatcgcc ttgaaagctc tgaagaggcc   3060

ctgggttgcc gcggcagcag tggtctgttt gatgctgccg tttgccgctg ccggcccctc   3120

ctcagactcc gcctttggga gcacacctgc tttgccttgc tgcctgtgca aatgttggac   3180

aagcagacac actcacactc gtccccagct tagcacagag ctggagcgcc catttctgga   3240

attttccgtt tgggaatctc cacttctggg gtttacctgt tcggcctcct gtctatcagt   3300

gaggcatctc tgactgtttc ttctactgct tttcagttcc cttccctgct gttctatttc   3360

ctttgagtgt aaagactcac aggtgacctg ctatcgagat agccagaggg tcaggagaga   3420

atgggggagg aggcggtcag gctgctgagg aaacaccaca ggctgaacgg gggaggaatg   3480

cacatgccac gctgggtgtc ccgggtcgcg gggaggcagc tcagctctta ggagcaagtt   3540

gtgggggctt ttcaagaggg gccaggcttc ctggagggtg actgatgtgg ccgaagcagg   3600

tgtccaggca ggtaggctgc agccaggagc tccctggcac cgcaggacct cgtggtactc   3660

ttgccttaga ttttacacac actccacagc caagcactgc cacggtcctc caggacctgg   3720

gaagcaaagg cacaggccca cggtggccag ccattgtggt gccgccccag cttctggata   3780

cagccttttg ggtaaacact gggaactcca gaagttgtgg ggagagtggg gaatcagaca   3840

gccgcctcta ggggctgggt tctgctgggg cctccttgtt ggtgctgtag gcacccgcca   3900

gggagcaggg acccgacttg cagacgcatt gcccggtact aggaaggagt gaggtgtgtt   3960

cccaccgtac acttcccaca cgagctgcgg ctgccagcct cgggccatca gcctaggaga   4020

gcagatgcag ctccaggggc tcgacttata gccagttaca gctccccggc tcttctgtgt   4080

ggcagagcgt cgtttccggg ccctcagggc tggggagctc agttcccatt gcttgtgctc   4140

agggctgagt cttaaagaag ggtttgccgg ccctaacgct gcagcgcgtg cgcggtgaga   4200

ggcccttttt gagcctgttt actcctgtgg ccttgggcag aacagtaaat actctgtgca   4260

cggaggaaag acatgcccaa gaggaaggaa gtactgacca tcggctgcct gtgagcagct   4320

tagcaaggag cccttgctcc ctgggaaagg cggtgaactt gagtctaaag atgcagtgcc   4380

tggcccttcc taaggtccct gcctggcatc cgagtgtcgg tgtgtggcac agaaggctcc   4440

tgcttgcttc caaagtgatg gacaggaagg ggcagagtga gtcacggccc agactgggca   4500

ccttcgcgtc tcagcctcag ggagccccac agccccaagc tcgctgaggc aacgtgagaa   4560

caggctatgg gaaggctgca aaggctgaga aatgcaaagg ctcatattta taaatcccac   4620

ccccagagtg gggagggtca ggtgccagac ctggactaaa ctgcaccaag gaaacaccca   4680

gcagggtctc ctgtgagccg gggaccatgc agcccgaaac ctccagtcac tgcgcccggc   4740

aggagtcagg agccagggac tgtgcagcct ggaacctcca gtcactgtgc ccagcagggt   4800

gggctgtgcc cagcaggagt caggctaaga aacgccaggt ctgcctgttc ttgctgggca   4860

atggctgatg gctgccagtt tctgctgata cacaggtagg atgggaccct tcatgaatat   4920

ctgactttaa taagttggta aggatatatt tttttgtcta tgttctgttt caacttatgt   4980

agattattat aaattgatgt aaaccacgtg agaggaaaat gttaataaaa aatgcaaagc   5040

cccatcattt gcacaaaact cagaaaaaa                                     5069


<210>  642
<211>  4097
<212>  DNA
<213>  Human

<400>  642
gcacccaggt cgggcggtgg gggcgagcgg aggggctgag gggcggagag gcctggcggg     60

ccgctgctgc gggccagggg acgggggcgg agccggagcc ggagccgacg ggcggtggcc    120

gcactgggac cccggaatcc cgcgcgctgc ccacgattcg cttctgagga acctagaaag    180

attgtacaat gaatggtgat tctcgtgctg cggtggtgac ctcaccaccc ccgaccacag    240

cccctcacaa ggagaggtac ttcgaccgag tagatgagaa caacccagag tacttgaggg    300

agaggaacat ggcaccagac cttcgccagg acttcaacat gatggagcaa aagaagaggg    360

tgtccatgat tctgcaaagc cctgctttct gtgaagaatt ggaatcaatg atacaggagc    420

aatttaagaa ggggaagaac cccacaggcc tattggcatt acagcagatt gcagatttta    480

tgaccacgaa tgtaccaaat gtctacccag cagctccgca aggagggatg gctgccttaa    540

acatgagtct tggtatggtg actcctgtga acgatcttag aggatctgat tctattgcgt    600

atgacaaagg agagaagtta ttacggtgta aattggcagc gttttataga ctagcagatc    660

tctttgggtg gtctcagctt atctacaatc atatcacaac cagagtgaac tccgagcagg    720

aacacttcct cattgtccct tttgggcttc tttacagtga agtgactgca tccagtttgg    780

ttaagatcaa tctacaagga gatatagtag atcgtggaag cactaatctg ggagtgaatc    840

aggccggctt caccttacac tctgcaattt atgctgcacg cccggacgtg aagtgcgtcg    900

tgcacattca caccccagca ggggctgcgg tctctgcaat gaaatgtggc ctcttgccaa    960

tctccccgga ggcgctttcc cttggagaag tggcttatca tgactaccat ggcattctgg   1020

ttgatgaaga ggaaaaagtt ttgattcaga aaaatctggg gcctaaaagc aaggttctta   1080

ttctccggaa ccatgggctc gtgtcagttg gagagagcgt tgaggaggcc ttctattaca   1140

tccataacct tgtggttgcc tgtgagatcc aggttcgaac tctggccagt gcaggaggac   1200

cagacaactt agtcctgctg aatcctgaga agtacaaagc caagtcccgt tccccagggt   1260

ctccggtagg ggaaggcact ggatcgcctc ccaagtggca gattggtgag caggaatttg   1320

aagccctcat gcggatgctc gataatctgg gctacagaac tggctaccct tatcgatacc   1380

ctgctctgag agagaagtct aaaaaataca gcgatgtgga ggttcctgct agtgtcacag   1440

gttactcctt tgctagtgac ggtgattcgg gcacttgctc cccactcaga cacagttttc   1500

agaagcagca gcgggagaag acaagatggc tgaactctgg ccggggcgac gaagcttccg   1560

aggaagggca gaatggaagc agtcccaagt cgaagactaa ggtgtggacg aacattacac   1620

acgatcacgt gaaacccttg ctgcagtctc tctcgtccgg tgtctgcgtg ccaagctgta   1680

ttaccaactg cttgtggact aaagaggatg gacatagaac ttccacctct gctgtcccta   1740

acctgtttgt tccattgaac actaacccaa aagaggtcca ggagatgagg aacaagatcc   1800

gagagcagaa tttacaggac attaagacgg ctggccctca gtcccaggtt ttgtgtggtg   1860

tagtgatgga caggagcctc gtccagggag agctggtgac ggcctccaag gccatcattg   1920

aaaaggagta ccagccccac gtcattgtga gcaccacggg ccccaacccc ttcaccacac   1980

tcacagaccg tgagctggag gagtaccgca gggaggtgga gaggaagcag aagggctctg   2040

aagagaatct ggacgaggct agagaacaga aagaaaagag tcctccagac cagcctgcgg   2100

tcccccaccc gcctcccagc actcccatca agctggagga aggagacgga tgcgctagag   2160

agtacctgtt accctaacct tgtgccggag ccgactactg gagatgacag tgatgctgcc   2220

acctttaagc caactctccc cgatctgtcc cctgatgaac cttcagaagc actcggcttc   2280

ccaatgttag agaaggagga ggaagcccat agacccccaa gccccactga ggcccctact   2340

gaggccagcc ccgagccagc cccagaccca gccccggtgg ctgaagaggc tgccccctca   2400

gctgtcgagg agggggccgc cgcggaccct ggcagcgatg ggtctccagg caagtccccg   2460

tccaaaaaga agaagaagtt ccgtaccccg tcctttctga agaagagcaa gaagaagagt   2520

gactcctgaa agccctgcgc taacactgtc ctgtccggag cgaccctggc tctgccagcg   2580

tccccggcca cgtctgtgct ctgtccttgt gtaatggaat gcaaaaaagc caagccctcc   2640

gcctagaggt cccctcacgt gaccagcccc gtgtagcccc gggctgaccc agtgtgtgct   2700

cagcagcccc accccaccct gccccttgtc ctctcagagc ctcagcttct gggggagaca   2760

tgctctcccc acagggggga ggcactaagt catggtcctg gctggaaggt actgaaggct   2820

tctgcagctt tggctgcacg tcaccctcct gagcctcacc tttcctgccg tccctcctgt   2880

tgtgaaatca ccacattctg tctctgcttg gcttcccctc caccctaaag tctcaggtga   2940

cggactcaga ctcctggctt catgtggcat tctctctgct cagtgatctc acttaaatct   3000

atatacaaag ccttggtccc gtgaaaacac tcgtgtgccc accagcggcc ttgaagaggc   3060

aggtctgggc cagatgctgg gcaggaaacc ccagcggcag atgggcctgt gtgcacccaa   3120

cgtgatgcta tgcatgtctg accgacgatc cctcgaccag aatcagattc aggagctcag   3180

tttctttttc acttgggtct ctggattcct gtcataggga aggtatatca ggaggggaag   3240

aggcctttct agaattttct ttgagcaggt ttacaattta gcttacattt ttcgactgtg   3300

aacgtgaata ggctgctttt tgctttcttc tttccagacc ccacagtaga gcacttttca   3360

cttatttggg ggaggcttca ggggactgtt ctcaccttaa ctcagccaga aagatgccct   3420

agttgtgatc aaaggtaact cgaggtggag ggtagccctg gggcccctcg acatcaccgt   3480

cattgatgga gcctgaaccg tgtgctcctc ggcagatgct gttgttgtta cttccctcca   3540

agaggctgga aaagggctca gagctgctga gcaggaaccg gagggtgacc catttcagga   3600

ggtgccggta ccagcctgac taggtacagg caagcttgtg tgggcccaac aggcccttgg   3660

tagagctggt gccagatgtg ggctcagatc ctgggcatga tgggccgagc cacctcggat   3720

cccactgatt ggccagccga gcgagaacca ggctgctgca tggcactgac cgccgcttcc   3780

agcttcctct gagccgcagg gcctgctacg cgggcaagcg tgctgcctct cttctgtgtc   3840

gttttgttgc caaggcagaa tgaaaagtcc ttaaccgtgg actcttcctt tatcccctcc   3900

tttaccccac atatgcaatg acttttaatt ttcacttttg tagtttaatc ctttgtatta   3960

caacatgaaa tatagttgca tatatggaca ccgacttggg aggacaggtc ctgaatgtcc   4020

tttctccagt gtaacatgtt ttactcacaa ataaaattct ttcagcaagt tccttgtcta   4080

aaaaaaaaaa aaaaaaa                                                  4097


<210>  643
<211>  1685
<212>  DNA
<213>  Human

<400>  643
atgcgcgtcc acgcctccct ataagataaa gcgcggccga cgggctccga gcgcggcccc     60

tgggttcgaa cacggcaccc gcactgcgcg tcatggtgca ggcctggtat atggacgacg    120

ccccgggcga cccgcggcaa ccccaccgcc ccgaccccgg ccgcccagtg ggcctggagc    180

agctgcggcg gctcggggtg ctctactgga agctggatgc tgacaaatat gagaatgatc    240

cagaattaga aaagatccga agagagagga actactcctg gatggacatc ataaccatat    300

gcaaagataa actaccaaat tatgaagaaa agattaagat gttctacgag gagcatttgc    360

acttggacga tgagatccgc tacatcctgg atggcagtgg gtacttcgat gtgagggaca    420

aggaggacca gtggatccgg atcttcatgg agaagggaga catggtgacg ctccccgcgg    480

ggatctatca ccgcttcacg gtggacgaga agaactacac gaaggccatg cggctgtttg    540

tgggagaacc ggtgtggaca gcgtacaacc ggcccgctga ccattttgaa gcccgcgggc    600

agtacgtgaa atttctggca cagaccgcct agcagtgctg cctgggaact aacacgtgcc    660

tcgtaaaggt ccccaatgta atgactgagc agaaaatcaa tcactttctc tttgctttta    720

gaggatagcc ttgaggctag attatctttc ctttgtaaga ttatttgatc agaatatttt    780

gtaatgaaag gatctagaaa gcaacttgga agtgtaaaga gtcaccttca ttttctgtaa    840

ctcaatcaag actggtgggt ccatggccct gtgttagttc atgcattcag ttgagtccca    900

aatgaaagtt tcatctcccg aaatgcagtt ccttagatgc ccatctggac gtgatgccgc    960

gcctgccgtg taagaaggtg caatcctaga taacacagct agccagatag aagacacttt   1020

tttctccaaa atgatgcctt ggggtgggga gtggtagggg gaagagctcc caccctaagg   1080

ggcacacact gagttgctta tgccacttcc ttgttcaaaa taaagtaact gccttaatct   1140

tatactcatg gcttggagtt accttatatt caggtatatg tgatattttg cctggtttgt   1200

taaaattgcc ccatttagat tccttctata attgttctta tagataagta atttatatat   1260

gagctgtgtt agtatttttt cagtgtgaga tctctggatt ctttcacaat aaagctgttg   1320

aattttaaca ggagtattag tacataaatt ttctactcaa caattccgag ataggattat   1380

gcctagtttg tcatatcaca gaaaaactcc aagttaactt catgttttgg aagggcaggt   1440

cgtttttaaa gtatttcttt ttttaactgg atgaaaaatc ttcatgttag gattaatttt   1500

cttaatcacc tccacactgt acagaggaaa ctcaagcctt aaatgtttaa gtaaactctg   1560

tctcagtttt aggattaaaa tacccaccgg tggtgtgatg atgccatata ccgcagggct   1620

tgcttctgtc aagtgtgact ctatctcagt aattaaaata agtgctgatc tactgaaaaa   1680

aaaaa                                                               1685


<210>  644
<211>  3159
<212>  DNA
<213>  Human

<400>  644
agtgacagag cgattactaa gcctacggtt cccaaacgac tcaggtgaac ctgatttaca     60

ggaaaggcgg gctgtagcta gggatggaga cagtacctat cagcaagcgg ctccacagct    120

cggttctcta tctattctga agacatgcgg ggccactcac tgctcctgat agtcctctac    180

ctcccacaga ccccacccac tacgacacgg aaaactggat tacccaaata cctgcctctg    240

agtctgggga cgcaggcaag cacaaagaca agggggatgg agcttctaca cagggcccca    300

gcgctgtcgc tgtggctgct gctgccgcta cggcttagtg caccagacgc tgcatttcag    360

gtgctcctac aaaagaggcc actcctggaa cgccgggagc tcagacgctg ccctttgctc    420

gcgagccaag tcagccaagg ttaaccttcg cggaacccgg cgaggagcgc aagcctggcc    480

ttccccaaac acagatccga gcttttcacc ctctaccctc ccctcagcct ggccttttct    540

tccgccctca cagccaccgc gacccaacgc tgaggaaaga ccccgacttg tggtgtcctt    600

ccccttgccc aaactggcca cgaaaggaca tatagcgaga gagaaagagg attttctgcc    660

gtctcttggc aaaaatggca aataatgatg ctgttctgaa gagactggag cagaagggtg    720

cagaggcaga tcaaatcatt gaatatctta agcagcaagt ttctctactt aaggagaaag    780

caattttgca ggcaactttg agggaagaga agaaacttcg agttgaaaat gctaaactga    840

agaaagaaat tgaagaactg aaacaagagc taattcaggc agaaattcaa aatggagtga    900

agcaaatacc atttccatct ggtactccac tgcacgctaa ttctatggtt tctgaaaatg    960

tgatacagtc tacagcagta acaaccgtat cttctggtac caaagaacag ataaaaggag   1020

gaacaggaga cgaaaagaaa gcgaaagaga aaattgaaaa gaaaggagag aagaaggaga   1080

aaaaacagca atcaatagct ggaagtgccg actctaagcc aatagatgtt tcccgtctgg   1140

atcttcgaat tggttgcatc ataactgcta gaaaacaccc tgatgcagat tctttgtatg   1200

tggaagaagt agatgtcgga gaaatagccc caaggacagt tgtcagtggc ctggtgaatc   1260

atgttcctct tgaacagatg caaaatcgga tggtgatttt actttgtaac ctgaaacctg   1320

caaagatgag gggagtatta tctcaagcaa tggtcatgtg tgctagttca ccagagaaaa   1380

ttgaaatctt ggctcctcca aatgggtctg ttcctggaga cagaattact tttgatgctt   1440

tcccaggaga gcctgacaag gagctgaatc ctaagaagaa gatttgggag cagatccagc   1500

ctgatcttca cactaatgat gagtgtgtgg ctacatacaa aggagttccc tttgaggtga   1560

aagggaaggg agtatgtagg gctcaaacca tgagcaacag tggaatcaaa taaaatgctt   1620

ccactaccaa aagacattag agaaaacctt aaaagtaata aagagaaata tatttgtcac   1680

ttatacctaa aatatgagtg gctcattttt gcattactct cttctagact tgactagtca   1740

tttacttggt atatattgtt ttcattgatt ggggaaacac tagattttta cctcggtttt   1800

tgatcattta taatggagag aggaagttgc ctatgttttg taataattta ttttttagca   1860

ggaatattga ttagcagctt ttttttcttt atacacatag ataactaact agattaatgt   1920

ttagtttctt atttgtaggc acaggatgca tgaaatttca agctctggga ttttttgtat   1980

attgtgtatc tgtatcaaaa atatcctctc cttttcaaaa atgacaggtt ggaaaatgtt   2040

tgtcagactt attaactggt catattataa taatactgat aatgaccaac tgctcattct   2100

gaaagccaaa cataaaagct aggagaagtg gcatctgaac atttttgctt tgctgccaga   2160

gtaaccctga ctaataatac aataacagca atttttttaa aaaactgaga tttcctactg   2220

gcttgaagtt tttctattta gcaaaataat tagtaataag ttttgactag gtctaaagaa   2280

tgaacacatt gtaaacagtt gccacagtag tttctaataa attgatcata aaagcagcta   2340

tccttttttt ttttaattct agcttctttt taaagattat ttgggtacct aataaaggat   2400

aatttatatc ttattacaga ctgatatttt gctttttcat gtgtcatcat actgtcagta   2460

tattaaaaga aattacagcc taaaacttaa catataccat acatatatat taaggtgtca   2520

aatagctatt ctcactcatc ttacaaatat tgtaagagca ataaaaatta attgaggaat   2580

tataagccta caggtcatca gccttgaggt gattactgat gatttgggct tacacacatg   2640

tcagcaagat agggagtgtg gataggggag ggctggtagc taacaagggg cctcacagag   2700

aaatattagt gactttaacc aggtttcaga atctgggcct tacctttaca ggttcaacaa   2760

aagaatggca tcaatagagg cagaagtata gacattgttt taaaaataca cacatgcaca   2820

cacacacaaa acattttagc attatagctg tctgaatcct tcaataagaa ggagaggcac   2880

acacaaatac acacactcac acaaaactca acaaccataa aacaaccctg catgttataa   2940

aaggcagaat taaattttat ttatttaaat ccatggaact ctggtaggcc aggatatatt   3000

atagtaccat tatcaatgtg atattctgaa aatatgaact gagcgtcatt aacaattgtt   3060

ggtacctaaa cacaaaatga atttcaaaag ttactttgtt ctcaagatat gtcattcttt   3120

tgggaataaa tacttctggt gacaaaaaaa aaaaaaaaa                          3159


<210>  645
<211>  2646
<212>  DNA
<213>  Human

<400>  645
ggctggggcg gccctgagga cgcgtgcggg gcaggtcacg cttgggcctg gctgcctcag     60

gagccaccct gcacggcgcc gggcgaggct gtgcgcgccc tcccggaccc tccactttgg    120

ggctttgcgg tgtagcggcg cgccccactc ccttacgtgt tcagtcccga atcacgtacg    180

ggccgctgca gctccaggac ggcggacgcc agcgctctcg gatccccagg cccctccgtg    240

ctcatcccgg accgctccgt ccctgaggaa aaaccgcccc gtgcccggaa ccgcggcttc    300

tcccacgcgg ggcaggccgg ggctgtgagg gggcagcccg cctgcggact aggccggggg    360

tttgaggagg cggctctgcc ggggacaaag ccgggggcgt gaggggcggt tctgccgggt    420

tcggggcgcg cggggcaggt tgcgtgaaga ggcggaaagt cccactcgcc ctcggcttct    480

ccctgcccgg ccgccggtgt cccgcccgcc gcctccccgc gcagcccggc ccgacccgcg    540

gcgatggccc agcccgggga cccgcggcgc ctctgcaggc tggtgcagga gggccggctg    600

cgcgccctga aggaggagct gcaggcggcc gggggctgcc cggggccggc cggggatacc    660

ctcctgcact gcgccgcgcg ccacgggcat cgggacgtgc tggcctatct ggccgaggcc    720

tggggcatgg acatcgaggc caccaaccga gactacaagc ggcctctgca cgaggcggcc    780

tccatgggcc accgagactg cgtgcgctac ctgctgggcc ggggggcagc ggtcgactgc    840

ctgaagaagg ccgactggac tcctctgatg atggcctgca caaggaagaa cctgggggtg    900

atccaggagc tggtggaaca tggcgccaat ccactcctga agaacaaaga tggctggaac    960

agtttccaca ttgccagtcg agaaggcgac cctctgatcc tccagtacct gctcactgtt   1020

tgcccaggtg cctggaagac agagagcaaa attagaagga ctcctctgca tactgcagca   1080

atgcatggcc atttggaggc agtcaaggtg cttcttaaga ggtgccaata tgaaccagac   1140

tacagagaca actgtggcgt caccgccttg atggacgcaa tccagtgtgg gcacatcgac   1200

gtcgctaggc tgctcctcga tgaacatggg gcttgccttt cagcagaaga cagcctgggt   1260

gcccaggctc tgcacagggc agctgtcaca gggcaggacg aagccatccg attcttggtc   1320

tctgaacttg gcgtcgatgt agatgtgaga gccacatcaa cccacctcac agcacttcat   1380

tatgcagcta aggaaggaca tacaagtaca attcagactc tcttatcctt gggagctgac   1440

atcaattcta aagatgaaaa aaatcgatca gccctgcatc tggcctgtgc aggtcagcac   1500

ttggcctgtg ccaagtttct cctgcagtcg ggactgaagg attctgaaga catcacgggc   1560

accctggctc agcagctccc aaggagagca gatgtccttc agggctctgg ccatagcgca   1620

atgacataag gatgtttcca agaggaggca ataaagtgca tgagttgctg ggagcctgag   1680

cacctttcgt ttttcggctc agagaaagcc aagtgcaact tgcttcagtc atcctgaacc   1740

tgagttcaac caaccgcagc cacctacgtt tgaccccagc gagatcaaag ttgtatatct   1800

gaggtgtacc agtggtgaag tcagtgccac atctgcactg gcccccaagg tcagctccct   1860

gggtctgtct ccaaaaatgg ttgctgatga catcaccaac cattgactgg aagagtctga   1920

ggatgatagt gaaactgacc agccacagca gacaggccca gattgaggtg gtgccttctg   1980

cctctgccct gatcgtcaca accctcagga accaccgaca gaaagaaaga aacacaaaaa   2040

catgaaacac agtggtagca ccacttctga tgagattgtc aacattgcct aacagatgca   2100

gcagcagtct ttagccagag aactctctgg aaccattaaa gaattcctgg gggccggttg   2160

cggtggctca tgcctgtaat cccagcactt tgggaggccg aggcgggagg atcatgaggt   2220

caggagatcg agaccatcct ggctaacgtg gtgaaacccc gtctcttact aaaaatacaa   2280

aaaaattagc caggcatggt ggtgggcgcc tgtagtccca gctactcagg aggctgaggc   2340

aggagaatgc tgtgaaccct ggaggcagag cttgcagtga gccgaatatg cgccactgca   2400

ctccagcctg ggcaacagag caagactccg tctccaaaaa aaaaaaaaaa aaaaaagaat   2460

tcctggggcc tgcccagtct gtgagctgcc atgttgatag tatcacagat gataccaaca   2520

gtgaagctgt ggaatgccca gctagttaaa gaatgcaaag gaaaatattt tcacaaaggg   2580

ttatctgata accaaaaaaa aaaaagacat ttcatctaag ccacttaaaa aaaaaaaaaa   2640

aaaaaa                                                              2646


<210>  646
<211>  1223
<212>  DNA
<213>  Human

<400>  646
gggatccttg agtcctactc agccccagcg gaggtgaagg acgtccttcc ccaggagccg     60

actggccaat cacaggcagg aagatgaagg ttctgtgggc tgcgttgctg gtcacattcc    120

tggcaggatg ccaggccaag gtggagcaag cggtggagac agagccggag cccgagctgc    180

gccagcagac cgagtggcag agcggccagc gctgggaact ggcactgggt cgcttttggg    240

attacctgcg ctgggtgcag acactgtctg agcaggtgca ggaggagctg ctcagctccc    300

aggtcaccca ggaactgagg gcgctgatgg acgagaccat gaaggagttg aaggcctaca    360

aatcggaact ggaggaacaa ctgaccccgg tggcggagga gacgcgggca cggctgtcca    420

aggagctgca ggcggcgcag gcccggctgg gcgcggacat ggaggacgtg tgcggccgcc    480

tggtgcagta ccgcggcgag gtgcaggcca tgctcggcca gagcaccgag gagctgcggg    540

tgcgcctcgc ctcccacctg cgcaagctgc gtaagcggct cctccgcgat gccgatgacc    600

tgcagaagcg cctggcagtg taccaggccg gggcccgcga gggcgccgag cgcggcctca    660

gcgccatccg cgagcgcctg gggcccctgg tggaacaggg ccgcgtgcgg gccgccactg    720

tgggctccct ggccggccag ccgctacagg agcgggccca ggcctggggc gagcggctgc    780

gcgcgcggat ggaggagatg ggcagccgga cccgcgaccg cctggacgag gtgaaggagc    840

aggtggcgga ggtgcgcgcc aagctggagg agcaggccca gcagatacgc ctgcaggccg    900

aggccttcca ggcccgcctc aagagctggt tcgagcccct ggtggaagac atgcagcgcc    960

agtgggccgg gctggtggag aaggtgcagg ctgccgtggg caccagcgcc gcccctgtgc   1020

ccagcgacaa tcactgaacg ccgaagcctg cagccatgcg accccacgcc accccgtgcc   1080

tcctgcctcc gcgcagcctg cagcgggaga ccctgtcccc gccccagccg tcctcctggg   1140

gtggacccta gtttaataaa gattcaccaa gtttcacgca aaaaaaaaaa aaaaaaaaaa   1200

aaaaaaaaaa aaaaaaaaaa aaa                                           1223


<210>  647
<211>  2614
<212>  DNA
<213>  Human

<400>  647
ctccctgttt ctgtcttgaa cctgattctt tcttcttatc tccttcctgt gtccacctca     60

agactcccac cactacccag gaccaactcc tgctcctgaa tcttctgatg ggccccacaa    120

ggtgacagtg ctggctacaa tgctatccag ccggtggtgg ccaagttcct gggggatcct    180

agggctgggc ccccgaagcc ctcctcgggg atcccagctc tgtgccctct atgcctttac    240

ttatactggg gcagatggcc agcaggtgtc tctggctgaa ggggataggt tcctactgct    300

tcgaaagacc aactccgact ggtggttggc aagacgccta gaagctccct ccacctctcg    360

acccatcttc gtcccagcag cctatatgat agaggaatcc atcccttccc agagtccaac    420

taccgtcatc cccggccaat tgctctggac tcctgggccg aagttgtttc atggttccct    480

ggaggagttg tctcaggccc tcccaagcag ggctcaggct agctcggagc agcctcctcc    540

acttccccgc aaaatgtgta ggagcgtcag cactgacaat ctgagcccca gccttctgaa    600

gcctttccag gaaggaccaa gcggaagatc cctctcccag gaagacttgc cgtcagaagc    660

cagtgccagc acagcaggcc cccagcccct catgtcagag ccccctgtgt actgtaacct    720

ggtggacctt cgccgctgtc ctcggtcccc acccccaggc cctgcatgcc ccctgctgca    780

gaggctggat gcctgggagc agcacctgga ccccaactct ggacgctgct tctacataaa    840

ttcactgact ggctgcaagt cctggaagcc cccgcgccgc agtcgcagcg agacgaaccc    900

tggctccatg gaggggacac agaccctgaa gaggaacaat gatgtcctgc aacctcaggc    960

aaagggcttc agatctgaca cagggacccc agaaccgctt gacccacagg gttcactcag   1020

cctcagccaa cgcacctcgc agcttgaccc tccagccttg caggcccctc gacctctgcc   1080

gcagctcctg gacgaccccc atgaggtgga aaagtcgggt ctgctcaaca tgaccaagat   1140

tgcccaaggg gggcgcaagc tcaggaagaa ctggggcccg tcttgggtgg tgttaacggg   1200

taacagcctg gtgttctacc gagagccacc gccgacagcg ccctcctcag gctggggacc   1260

agcgggtagc cggcccgaaa gtagcgtgga cctgcgcggg gcggccctgg cgcacggccg   1320

ccacctgtcc agccgccgca acgtcctgca catccgcacg atccctggcc acgagttcct   1380

gctgcagtcg gaccacgaga cagagctgcg agcctggcac cgcgcgctgc ggactgtcat   1440

cgagcggctg gatcgggaga accccctgga gctgcgtctg tcgggctctg gacccgcgga   1500

gctgagcgcc ggggaggacg aagaagagga gtcggagctg gtgtccaagc cgctgctgcg   1560

cctcagcagc cgccggagct ccattcgggg gcccgaaggc accgagcaga accgcgtgcg   1620

caacaaacta aagcggctca tcgcgaagag accgccctta caaagcctgc aggagcgggg   1680

tctgctccga gaccaggtgt tcggctgcca gttggaatca ctctgccagc gggaaggaga   1740

cacggtgccc agctttttgc ggctctgcat tgctgctgtg gataaaagag gtctagatgt   1800

ggatggcatt tatcgggtga gcgggaactt ggcagtggtc cagaagcttc gctttctggt   1860

ggacagagag cgtgcggtca cctccgatgg gaggtatgtg ttcccagaac agccaggaca   1920

agaaggtcgg ttagatttgg acagtactga gtgggatgac attcatgtgg tcaccggagc   1980

cctgaagctt tttctccggg agctgcccca gcctctggtg ccaccactgc tgctgcccca   2040

tttccgtgct gcccttgcac tctccgaatc agagcagtgc ctctctcaga tacaagaatt   2100

aataggctca atgccaaagc ccaaccatga cactctacgg tacctcctgg agcatttatg   2160

cagggtgata gcacactcag ataagaatcg catgacaccc cacaacctgg gaattgtgtt   2220

tggaccaacc ctgtttcggc cagagcagga gacatctgac ccagcagccc atgctctcta   2280

cccagggcag ctggtccagc tgatgctcac caacttcacc agcctcttcc cctgatgcag   2340

ggaaggaaga agagaaaaca tatttccggt catctctggt ggtgagaggc tggtgttctg   2400

ttttgaggat atccctttaa atctcccaaa tgactgtctc tatcttcatg agtgtgactt   2460

gaggtgttgg gatgggtgag ggagcttctc taaagaggaa agtgagtgga ttaacccctg   2520

cttctcttct tgttccctgt tatcattcct ccccaacata ataatacata aagtggcatg   2580

gtattttttc tgatgcaaaa aaaaaaaaaa aaaa                               2614


<210>  648
<211>  3522
<212>  DNA
<213>  Human

<400>  648
ctcaccccgg ccgtccggcc gcttcattgt caccgggcct cggggcagtg ttgggggtgg     60

cggggcgcca ggtcgccgac ccgaggtttg ggcgcgactg gttccgcatc ccctccccgc    120

cggccgaatc tgcaggcccc gcgcgccagg caggcttcgc ggctgcgccc ccggcccgcg    180

caggacctgc cttgtccacc atgaaaggca cccgggccat cggcagcgtc ccggagcgca    240

gcccagcagg tgtggacctg agtctgacag gtctccctcc gcctgtgtcc cggcgtcctg    300

gcagtgccgc caccaccaag cccatcgtcc gctctgtctc cgtggtcaca ggcagcgagc    360

agaagaggaa ggtgctggag gccacagggc ctgggggctc ccaggccatc aacaacctta    420

gaagatccaa cagcaccacg caggtcagcc agcctcggag cggctccccc aggccaacgg    480

agcccacaga cttcctgatg ctcttcgagg gcagccccag tgggaaaaag aggcctgcca    540

gcctgagcac agcccccagc gagaagggag ccacctggaa cgtcctggat gaccagcccc    600

ggggcttcac cttgccatcc aatgcccgga gttccagtgc ccttgactca ccagcgggcc    660

cgcggaggaa agaatgcacc gtggccctgg cccccaactt cactgctaac aacaggagca    720

acaagggagc agtgggcaac tgcgtcacca ccatggtgca caaccgctac accccctcgg    780

agagggcgcc tccgctcaag agctccaacc agactgcccc ctccctcaac aacatcatca    840

aggcagccac ctgtgagggc agtgagagca gcggctttgg gaagctgccg aagaatgtct    900

ccagtgccac ccactcagcc cggaacaata ctgggggcag cacgggcttg cccaggcgga    960

aggaggtgac ggaggaggag gctgagaggt ttatccacca ggtgaaccag gccactgtca   1020

ccatccagcg ctggtaccgg caccaggtgc agcggcgcgg agcaggagct gcccgcctgg   1080

agcacttgct tcaggccaag cgggaggagc agcggcagcg gtcaggcgag gggaccctct   1140

tggacctgca ccagcagaaa gaggcagcca ggaggaaggc ccgggaggag aaggcacgcc   1200

aagccaggcg agcagccatt caggagctgc aacagaaacg agccctgaga gcccagaagg   1260

cgagcactgc cgagcgtggg ccacctgaga atcccaggga gaccagagtg ccaggaatgc   1320

ggcagcctgc tcaggagctg tcccccacac caggcggcac tgcccaccag gccctcaagg   1380

ccaacaatac tggtggtggc ctccctgctg caggccccgg agaccgctgc ctgcccacct   1440

ccgactcatc cccagaacca cagcagcctc cagaggacag gacgcaggac gttcttgccc   1500

aggatgcagc tggggacaac ctggagatga tggccccgag cagggggagc gccaagtcca   1560

gggggccact ggaggagctg ctgcacacac tgcagctgct ggagaaggag ccggacgtgc   1620

tgccccgccc caggacccat cacaggggca gatacgcctg ggccagcgag gaggatgacg   1680

ccagctctct gacagctgac aacttggaga aatttggaaa actcagtgcg ttccccgaac   1740

ctcctgagga tgggacgctg ctatcggagg ccaagctaca aagcatcatg agcttcttgg   1800

acgagatgga gaagtctggg caggaccagc tggactccca gcaggagggg tgggtgccgg   1860

aggcggggcc ggggcccctg gagctggggt ccgaggtgag cacgtctgtg atgcggctga   1920

agctggaggt ggaggagaag aagcaggcca tgctgctgct gcagagagcg ctggcgcagc   1980

agcgagacct cacggcccgg cgggtcaagg agacagagaa ggcgctgagc cggcagctgc   2040

agcggcagag ggagcactac gaggccacca tccagcggca cttggccttc attgaccagc   2100

tgattgagga caagaaggtc ctgagtgaaa agtgcgaggc tgtggtggcc gagctgaagc   2160

aggaggacca gagatgcacc gagcgtgtgg cccaggcaca ggcgcagcac gagctggaga   2220

ttaaaaaact caaagaatta atgagcgcca ccgagaaagc ccgccgggag aagtggatca   2280

gtgagaaaac caagaagatc aaggaggtca ctgtccgagg tctggagccc gagatccaga   2340

agctgattgc aaggcacaag caggaagtgc ggaggctcaa gagcctgcac gaggcggagc   2400

tgctgcagtc ggatgagcgg gcctcgcagc gctgcctgcg ccaggccgag gagctgcggg   2460

agcagctgga gcgggagaag gaggcgctgg gccagcagga gcgcgaacgt gctcggcagc   2520

ggcagcgggc ggagctggaa gagctgaggc agcagctgga ggagagcagc tctgcactga   2580

cccgagccct gagggctgag tttgagaagg gcagggagga gcaggagcgc cggcaccaga   2640

tggagctgaa taccctgaag cagcagctgg agctggagag gcaggcgtgg gaggccggcc   2700

gcaccaggaa ggaggaggcg tggctgctga accgggaaca ggagctgagg gaagaaatcc   2760

ggaaaggccg ggacaaggag attgagctgg tcattcaccg gctggaggcc gacatggcgc   2820

tggccaagga ggagagtgag aaggctgccg agagccgcat caagcgctta cgggacaagt   2880

acgaggccga gctctccgag ctggagcagt cggagcggaa gcttcaggag cggtgctcgg   2940

agctgaaggg ccagcttggg gaggccgagg gcgagaatct gcgtctgcag ggccttgtgc   3000

ggcagaagga gcgggcgctg gaggatgcgc aggcggtgaa cgagcagctt tctagcgagc   3060

gcagcaacct ggcccaggtg atccgccagg agttcgagga ccggctggca gcctctgagg   3120

aggagacgcg gcaggccaag gccgagctgg ccacgctgca ggcccgccag cagctggagc   3180

tggaggaggt gcaccggagg gtgaagacag ccctcgcgag gaaggaggag gccgtgagca   3240

gcctccggac acaacatgag gctgcggtga agcgggccga ccacctggag gagctgctgg   3300

agcagcacag gaggcccacg ccaagtacca agtgaccagg gatgccggga acactgtcga   3360

agaacggaag gcagaggaca gaggctggac gtgggcccag aggcccacag ggacgcccac   3420

ctgcccccca cagaggctgg tggttgagat gcccacggct aagcacctgt ggctgcattt   3480

taacagtaaa ggaggccgtt gttttcagcg caaaaaaaaa aa                      3522


<210>  649
<211>  3682
<212>  DNA
<213>  Human

<400>  649
ggggccgccc ggcccgccca gcttcctctg gcggcgtccg gccgcttctc ctctgctcct     60

cgaagaaggc cagggcggcg ctgccgcaag ttttgacatt ttcgcagcgg agacgcgcgc    120

gggcactctc gggccgacgg ctgcggcggc ggccgaccct ccagagcccc ttagtcgcgc    180

cccggccctc ccgctgcccg gagtccggcg gccacgaggc ccagccgcgt cctcccgcgc    240

ttgctcgccc ggcggccgca gccatgtccc gggggcccga ggaggtgaac cggctcacgg    300

agagcaccta ccggaatgtt atggaacagt tcaatcctgg gctgcgaaat ttaataaacc    360

tggggaaaaa ttatgagaaa gctgtaaacg ctatgatcct ggcaggaaaa gcctactacg    420

atggagtggc caagatcggt gagattgcca ctgggtcccc cgtgtcaact gaactgggac    480

atgtcctcat agagatttca agtacccaca agaaactcaa cgagagtctt gatgaaaatt    540

ttaaaaaatt ccacaaagag attatccatg agctggagaa gaagatagaa cttgacgtga    600

aatatatgaa cgcaactcta aaaagatacc aaacagaaca caagaataaa ttagagtctt    660

tggagaaatc ccaagctgag ttgaagaaga tcagaaggaa aagccaagga agccgaaacg    720

cactcaaata tgaacacaaa gaaattgagt atgtggagac cgttacttct cgtcagagtg    780

aaatccagaa attcattgca gatggttgca aagaggctct gcttgaagag aagaggcgct    840

tctgctttct ggttgataag cactgtggct ttgcaaacca catacattat tatcacttac    900

agtctgcaga actactgaat tccaagctgc ctcggtggca ggagacctgt gttgatgcca    960

tcaaagtgcc agagaaaatc atgaatatga tcgaagaaat aaagacccca gcctctaccc   1020

ccgtgtctgg aactcctcag gcttcaccca tgatcgagag aagcaatgtg gttaggaaag   1080

attacgacac cctttctaaa tgctcaccaa agatgccccc cgctccttca ggcagagcat   1140

ataccagtcc cttgatcgat atgtttaata acccagccac ggctgccccg aattcacaaa   1200

gggtaaataa ttcaacaggt acttccgaag atcccagttt acagcgatca gtttcggttg   1260

caacgggact gaacatgatg aagaagcaga aagtgaagac catcttcccg cacactgcgg   1320

gctccaacaa gaccttactc agctttgcac agggagatgt catcacgctg ctcatccccg   1380

aggagaagga tggctggctc tatggagaac acgacgtgtc caaggcgagg ggttggttcc   1440

cgtcgtcgta cacgaagttg ctggaagaaa atgagacaga agcagtgacc gtgcccacgc   1500

caagccccac accagtgaga agcatcagca ccgtgaactt gtctgagaat agcagtgttg   1560

tcatcccccc acccgactac ttggaatgct tgtccatggg ggcagctgcc gacaggagag   1620

cagattcggc caggacgaca tccaccttta aggccccagc gtccaagccc gagaccgcgg   1680

ctcctaacga tgccaacggg actgcaaagc cgccttttct cagcggagaa aacccctttg   1740

ccactgtgaa actccgcccg actgtgacga atgatcgctc ggcacccatc attcgatgag   1800

aggacagcca aggactctcc cgggcctctc cggttctccc ttgcggaatg atgggcgcat   1860

cctgtctgcc acgtgctgac ggtcgggaag cttcagtgga gaggcctaac tctaatgtcg   1920

cctgcttaag caaatcatgc ttctctgttt cacgtagttg ggttgacaag tttctgcctt   1980

taagataaat gagtaatagt ctaatgacca gctcagccat ttaaaatatt ttcttcctat   2040

tctgttcaag aaacagtaaa cttggtttca atctttactg tattttttaa atgaattttt   2100

tccttaataa cagccagaat aagggatagt ctatgctttc aggactggct ttctgcacct   2160

gatatgaatg agaccagttt tattttataa agcatgtgct cttaatagca ttatgtctaa   2220

agaagatatc acgtaagttt gcatcttagc atgcaaatca taattttaag caatataaat   2280

tatgaaaata ctatataaat gtaatttaac ttaaaatgtt taagtgtaga gcttccagag   2340

atggagaaac ccccaccctc cctccaacca cgccagagct gtagagtgct aagacgcttt   2400

gcctgccctt atcacagcca cacgtagcac tcgacgaaat ctcctccgag agctcctttt   2460

cttggtagtt aggagtcgcc aacggattcg ctgcacacgg cccatccagg acacaggcct   2520

gggcgtcgga gtcacggctc cttgtgttct cactcagcta gttggccaaa gctgcatcca   2580

ttaccagtac actcaaactg ctcggggtcc tggtttctcc gtgtttgaat caggtacaga   2640

ctctcaaagg atacgtgtaa agccaggatg acctctggtg cctggagaag ggcgggtttt   2700

tcagcctagc agccatgatg ccctcggaac ctggccctat ggtatggatg tgaggactac   2760

gcactggctg ccctgagccc ggggctggaa atcatctttg gctgccaagg atctggacct   2820

attttggagt ggagagtcat ggttaaaatt cccagcccgg cccaggtacg ggaatcccag   2880

cattttgtga ggccgaggca gggggatcac ctgaggtcag gagtctctac taaaaataca   2940

aaaattagac aggtgtggtg gtgggcgcca ctcaggaggc tgaggcagga gaatcacttg   3000

aacccgggag gcagaggttg cagtgagcca gatcatgctg ctgcactcca gcccggccgc   3060

tcaccgtgtg tgttgctggg tgctggggct gtgacttatc ccctctcctt tagccttgcc   3120

ataagtgtag tatcctatga ggctgagatt gggaaaggtt acatgcaggt aagccagtgg   3180

acgtggccga tgcttcaggc tccttccagc caggtccagc agtgttacca tctgcttctc   3240

ctgggaggac aaaccaggca cccccaccat gaaggggctg caggcaccat gaactatgtt   3300

aacaacccca gtctgtacta cagaaagggc tgcagccaca tgagaattca gtccacacaa   3360

gccccatggc cgtgttcccc acttcagcca cagggctcag ggagccccat ctggcgctaa   3420

ggggaactgc tggggtgtgg gtgacacctg gcctttggcg ttctgccttg gggaggtttc   3480

tggttttgtt acggggtgga agaataggac ctgggggtct cggatgcaac ctgcagaccc   3540

cgtggctcac ccaaccccag gttctgcctc ccagaccaga acgggcatgg cctggtcctt   3600

ggcaccgagg tgcctgctct gtaaatatca agggattaca actttaataa taaagcagaa   3660

cttgaaaaca aaaaaaaaaa aa                                            3682


<210>  650
<211>  2174
<212>  DNA
<213>  Human

<400>  650
ttccctgaga cttccctcct ccctcccctc agctagggcc tgccggttcc tagtgcgtgc     60

ccagcagtcc tcaggtcacc ttcactaccg ggccaaggac cccgtgggaa ctcgcagcct    120

tcgccacact cgttcctcgc gcatccatgg aggggtgcct acagagaaga cctgcgtggc    180

aaaaacctaa acgaagagat gaggggcatg gagaggagta ggataagaga ataaagataa    240

cagtgggggg gagacgttag tttcctttat atcttttgtt actggcggta gcagtgaagt    300

tagaaacggt tttaaaacaa atttcagaca ggcattttcc aaaggcaagc ctggagcgca    360

cggatctgta taaccgcgga aggccctgtt tccggtccct tgcgcctgcg ctcttgcagc    420

caagaaggcg ggaggctgga gtagagggaa gcctgcaacc ggaagtgaag gcagatttcc    480

ctccttcgtc gctgttgctg ccgccatacg cgctctccct gtttagctct tctgttagaa    540

atagtatctt tgttttcctt tgctgttcct caatccccta ctcttcaccc cttgttttca    600

cctattttgc gagaacccat ccagatcccc cttcccttct tcccctgccg gcccagttat    660

ggcagagaac gatgtggaca atgagctctt ggactatgaa gatgatgagg tggagacagc    720

agctggggga gatggggctg aggcccctgc caagaaggat gtcaagggct cctatgtctc    780

catccacagc tctggctttc gtgacttcct gctcaagcca gagttgctcc gggccattgt    840

cgactgtggc tttgagcatc cgtcagaagt ccagcatgag tgcatccctc aggccattct    900

gggaatggat gtcctgtgcc aggccaagtc gggcatggga aagacagcag tgtttgtctt    960

ggccacactg caacagctgg agccagttac tgggcaggtg tctgtactgg tgatgtgtca   1020

cactcgggag ttggcttttc agatcagcaa ggaatatgag cgcttctcta aatacatgcc   1080

caatgtcaag gttgctgttt tttttggtgg tctgtctatc aagaaggatg aagaggtgct   1140

gaagaagaac tgcccgcata tcgtcgtggg gactccaggc cgtatcctag ccctggctcg   1200

aaataagagc ctcaacctca aacacattaa acactttatt ttggatgaat gtgataagat   1260

gcttgaacag ctcgacatgc gtcgggatgt ccaggaaatt tttcgcatga ccccccacga   1320

gaagcaggtc atgatgttca gtgctacctt gagcaaagag atccgtccag tctgccgcaa   1380

gttcatgcaa gatccaatgg agatcttcgt ggatgatgag acgaagttga cgctgcatgg   1440

gttgcagcag tactacgtga aactgaagga caacgagaag aaccggaagc tctttgacct   1500

tctggatgtc cttgagttca accaggtggt gatctttgtg aagtctgtgc agcggtgcat   1560

tgccttggcc cagctactag tggagcagaa cttcccagcc attgccatcc accgtgggat   1620

gccccaggag gagaggcttt ctcggtatca gcagtttaaa gattttcaac gacgaattct   1680

tgtggctacc aacctatttg gccgaggcat ggacatcgag cgggtgaaca ttgcttttaa   1740

ttatgacatg cctgaggatt ctgacaccta cctgcatcgg gtggccagag caggccggtt   1800

tggcaccaag ggcttggcta tcacatttgt gtccgatgag aatgatgcca agatcctcaa   1860

tgatgtgcag gatcgctttg aggtcaatat tagtgagctg cctgatgaga tagacatctc   1920

ctcctacatt gaacagacac ggtagaagac tcgcccattt tggaatgtga ccgtctgtcc   1980

ttcaggagag gacaccaggg tgggggtgaa ggagacacta ctgcccccac ccctgacagc   2040

ccccacccca tggcttccat cttttgcatc accaccactc ctgaaccccc atttctgatt   2100

tgtcagaatt tttttttaac aaaactaaaa atgaaacaca tgtgtctgtg gtatctataa   2160

aaaaaaaaaa aaaa                                                     2174


<210>  651
<211>  4907
<212>  DNA
<213>  Human

<400>  651
ggactgcggg ataggaagct ggggatatgg acaagcagca gcgttatagc gctctgggtt     60

tcgggacata ggcctgggcc atgcggcccc cttggcccct tggcgcgacc cccaggaacg    120

ttcggaaagc tggtcctcgt ggctggggga aaggcggggg gtggggggga agcgggcacg    180

tgaccccggt cagccaatct gggtgctgct gacgtggccg cgcggccccg atgctctccc    240

caccccccca gcccgttcgg gaagggaggg gctgggggct acgccccctc ccccagcacg    300

gcttcgtttt ctgggggggg gttgacaccc cggattacat accccgtacc aagccgaggg    360

caactttgga ggccccctgg aaggctttag gatccagatt cttcgctgct gctgccttac    420

cgccgagaac caccacccgc caggcgtctt gcggccacac ccctggcggg ttcaggcagg    480

ctacgcccac gcgacccctc ccgtttccct gctttggcca atggaggagc tacgaatggc    540

acgacctgct cgagcttggc agtctccagt tgggctgtgc atggaagctt gggaagactt    600

tgttggaagg ggaggcgggg agagagtgct ggaggctctg gggcgatggc ttccgcacct    660

cttccaacca ccctctttcc ctggagtcgg cggaccacag ctcagccaat tggcttggag    720

atgtggcggg ttgccacttc cctgtgggtc tctgcggcac tcttctgcct ggtgactgac    780

accttggaaa tgaagtttat gacgtcatcg ttgcggctgg ccaatagaaa aagctcccgc    840

ggagaggtgt tccttcccct tcgactcagc ttcttcaccc gcgtgagcga gcgcgcgcgc    900

gcggaggggg tggggaaaag ctcaagcagg gtggcgcgca tgagcggcga agctcctcct    960

ccccgcctat atataaaggg ctggcgcggg gctcggcggc gccatttcgt gctggagtgg   1020

agcagcctct agaacgagct ggaggattct gcctaccgat acagagcctt cgagtcgtcc   1080

ggggccgcca ttacaatcca cctccatccg cttggaaatg gccttcgtcc cggcctatga   1140

ctggtcccag cgggcagtac agacccccta gaagcccctg gagctcccct ttttcgggcc   1200

ccgcccaatc ctcggagtct gtccaccccc tctactccgc cctcaagagg atttcaaaga   1260

tggaggcggc ggctccctaa accacttttc gtgttcatcc gcctccatcc gagatcgaaa   1320

cgggacctcg tcggccccgt aggggcccga caagaagagg gaatccctgc agaccaacag   1380

cgggctatat tgacgacggt gtctgagatc ggggaccgtc ttttgaagag tcagtccctc   1440

cttagttgcc cgcctcagct gaggccgccg ccattttctt gctgtccgcc gtctgcagag   1500

cgcgccaagc tgcccggagc tctccgagag gccccaaaga gactgctttc gtgccggcca   1560

ggcagggggt ttgtcgcctg gaggcccaag aggaacggcc tccccccaac ttagcgggtt   1620

atgctggacc gggcggtgag gggaaccgag gccacccgga ctttccgcgg ctgagggcag   1680

cgccggttcc ttgcggtcaa gatgctgcaa aacgtgactc cccacaataa gctccctggg   1740

gaagggaatg cagggttgct ggggctgggc ccagaagcag cagcaccagg gaagaggatt   1800

cgaaaaccct ctctcttgta tgagggcttt gagagcccca caatggcttc ggtgcctgct   1860

ttgcaactta cccctgccaa cccaccaccc ccggaggtgt ccaatcccaa aaagccagga   1920

cgagttacca accagctgca atacctacac aaggtagtga tgaaggctct gtggaaacat   1980

cagttcgcat ggccattccg gcagcctgtg gatgctgtca aactgggtct accggattat   2040

cacaaaatta taaaacagcc tatggacatg ggtactatta agaggagact tgaaaacaat   2100

tattattggg ctgcttcaga gtgtatgcaa gattttaata ccatgttcac caactgttac   2160

atttacaaca agcccactga tgatattgtc ctaatggcac aaacgctgga aaagatattc   2220

ctacagaagg ttgcatcaat gccacaagaa gaacaagagc tggtagtgac catccctaag   2280

aacagccaca agaagggggc caagttggca gcgctccagg gcagtgttac cagtgcccat   2340

caggtgcctg ccgtctcttc tgtgtcacac acagccctgt atactcctcc acctgagata   2400

cctaccactg tcctcaacat tccccaccca tcagtcattt cctctccact tctcaagtcc   2460

ttgcactctg ctggaccccc gctccttgct gttactgcag ctcctccagc ccagcccctt   2520

gccaagaaaa aaggcgtaaa gcggaaagca gatactacca cccctacacc tacagccatc   2580

ttggctcctg gttctccagc tagccctcct gggagtcttg agcctaaggc agcacggctt   2640

ccccctatgc gtagagagag tggtcgcccc atcaagcccc cacgcaaaga cttgcctgac   2700

tctcagcaac aacaccagag ctctaagaaa ggaaagcttt cagaacagtt aaaacattgc   2760

aatggcattt tgaaggagtt actctctaag aagcatgctg cctatgcttg gcctttctat   2820

aaaccagtgg atgcttctgc acttggcctg catgactacc atgacatcat taagcacccc   2880

atggacctca gcactgtcaa gcggaagatg gagaaccgtg attaccggga tgcacaggag   2940

tttgctgctg atgtacggct tatgttctcc aactgctata agtacaatcc cccagatcac   3000

gatgttgtgg caatggcacg aaagctacag gatgtatttg agttccgtta tgccaagatg   3060

ccagatgaac cactagaacc agggccttta ccagtctcta ctgccatgcc ccctggcttg   3120

gccaaatcgt cttcagagtc ctccagtgag gaaagtagca gtgagagctc ctctgaggaa   3180

gaggaggagg aagatgagga ggacgaggag gaagaagaga gtgaaagctc agactcagag   3240

gaagaaaggg ctcatcgctt agcagaacta caggaacagc ttcgggcagt acatgaacaa   3300

ctggctgctc tgtcccaggg tccaatatcc aagcccaaga ggaaaagaga gaaaaaagag   3360

aaaaagaaga aacggaaggc agagaagcat cgaggccgag ctggggccga tgaagatgac   3420

aaggggccta gggcaccccg cccacctcaa cctaagaagt ccaagaaagc aagtggcagt   3480

gggggtggca gtgctgcttt aggcccttct ggctttggac cttctggagg aagtggcacc   3540

aagctcccca aaaaggccac aaagacagcc ccacctgccc tgcctacagg ttatgattca   3600

gaggaggagg aagagagcag gcccatgagt tacgatgaga agcggcagct gagcctggac   3660

atcaacaaat tacctgggga gaagctgggc cgagttgtgc atataatcca agccagggag   3720

ccctctttac gtgattcaaa cccagaagag attgagattg attttgaaac actcaagcca   3780

tccacactta gagagcttga gcgctatgtc ctttcctgcc tacgtaagaa accccggaag   3840

ccctacacca ttaagaagcc tgtgggaaag acaaaggagg aactggcttt ggagaaaaag   3900

cgggaattag aaaagcggtt acaagatgtc agcggacagc tcaattctac taaaaagccc   3960

cccaagaaag cgaatgagaa aacagagtca tcctctgcac agcaagtagc agtgtcacgc   4020

cttagcgctt ccagctccag ctcagattcc agctcctcct cttcctcgtc gtcgtcttca   4080

gacaccagtg attcagactc aggctaaggg gtcaggccag atggggcagg aaggctccgc   4140

aggaccggac ccctagacca ccctgcccca cctgcccctt ccccctttgc tgtgacactt   4200

cttcatctca cccccccccg cccccctcta ggagagctgg ctctgcagtg ggggagggat   4260

gcagggacat ttactgaagg agggacatgg acaaaacaac attgaattcc cagccccatt   4320

ggggagtgat ctcttggaca cagagccccc attcaaaatg gggcagggca agggtgggag   4380

tgtgcaaagc cctgatctgg agttacctga ggccacagct gccctattca cttctaaggg   4440

ccctgttttg agattgtttg ttctaattta ttttaagcta ggtaaggctg gggggagggt   4500

ggggccgtgg tcccctcagc ctccatgggg agggaagaag ggggagctct ttttttacgt   4560

tgattttttt ttttctactc tgttttccct ttttccttcc gctccatttg gggccctggg   4620

ggtttcagtc atctccccat ttggtcccct ggactgtctt tgttgattct aacttgtaaa   4680

taaagaaaat attattcaag ttttgagtta ccttaatatt tgcttttgta gtgtttcaaa   4740

aggaacatca taagaattgt cttgataatt ttgagggaaa tattactgca gtgagaaaag   4800

gcaatagcta acctataatt ggattgtctt aatttttaaa ccagtaggct tttgctgtgt   4860

ttttaataaa gtaaatatga cttttgtaaa ttgaaaaaaa aaaaaaa                 4907


<210>  652
<211>  1573
<212>  DNA
<213>  Human

<400>  652
ttttgcctag cgactgacaa caggctggtt gcttggcgtg gaatcctaaa gtggcctggc     60

tttgagactg gagtgagacc ccagccctag gctggggttc tttccattat agaggagacg    120

gattcaggag ggctacagac caaggttgtt gaaaaccaga catatgatga gcgtctagag    180

attaacgact ccgaagaggt tgcaagtatt tatactccaa ccccaagaca ccaaggactt    240

cctcgttctg cccatcttcc taacaaggct atggctgata acagcagtga tgagtgtgaa    300

gaggaaaata acaaggagaa gaagaagacc tcacagttga cacctcaacg gggctttagt    360

gaaaatgagg atgacgatgg tgatgatgat gattcatctg aaactgattc tgattctgat    420

gatgatgatg aagagcatgg agcccctctg gaaggggcct atgaccctgc agactatgag    480

catttgccag tttctgctga aattaaggaa ctcttccagt acatcagtag gtacacacct    540

cagttgattg acctggacca caaactgaag cctttcattc ctgattttat cccagctgtc    600

ggggatattg atgcattctt aaaggtccca cgtcctgatg gaaagcctga caaccttggc    660

ctattggtat tggatgaacc ttctacaaag cagtcagacc ctacggtgct ctcactctgg    720

ttaacagaga attctaagca gcacaacatc acacaacata tgaaagtaaa aagcctagaa    780

gatgcagaaa agaatcccaa agccattgac acgtggattg agagcatctc tgaattacac    840

cgttctaagc cccctgcgac tgtgcactac accaggccca tgcccgacat tgacacgctg    900

atgcaggaat ggtccccgga gtttgaagag cttttgggca aggtaagcct gcccacggca    960

gagattgatt gcagcctggc agagtacatt gacatgatct gtgccattct agacatccct   1020

gtctacaaga gtcggatcca gtccctccat ctgctctttt ccctctactc agaattcaag   1080

aactcacagc attttaaagc tctcgctgaa ggcaagaaag cattcactcc ttcatccaat   1140

tccacctccc aagctggaga catggagaca ttaaccttca gctgagacac ttcccaagct   1200

gctgtttcaa ggctgagctg gcccctctgc cccagctgag atggacagat cgttgtcagc   1260

tacttgatgt ccttgcccat gccacagctt ggctcagggg cagtgcatgt cctgctgccc   1320

tctctgccag agggcacaga acatgtttgt ttaatgaacc tgcctgcctc agattgctgt   1380

ccccggagag ttaatgcatc tacaccactg tggggatttg agttataaga attggaattt   1440

ctgagatccc atggaggtta gattgggagg aaagcttaaa agatgtcctt tttgtgagag   1500

ggatggaatt gttttctttc attcgtaaag ttagtgagta aagattttat aaatcaaatg   1560

ctctattata ttg                                                      1573


<210>  653
<211>  1671
<212>  DNA
<213>  Human

<400>  653
aggaagtgcg cgcggccccg cccccgccgg ttcgcgtctc tctgctgcgg cgcggggacc     60

gctgtgctct cggaagccat cttcgacaag agcacaggga aggttgtttt gaagacgttc    120

agcctctaca agaagctgct gactcttttc agagctggcc acgaccaggt ggtggtcctg    180

ctccatgatg tccgtgatgt gagcgtggag gaggagaagg tccggtactt cgggaaaggc    240

tacatggtgg tgctccggct tgcgacgggc ttctcccacc ccctcacgca gagtgcagtc    300

atgggccacc gcagtgatgt ggaagccatc gccaagctca tcaccagctt cctggagctg    360

cactgccttg agagccccac agagctgtct cagagcagcg acagtgaggc cggtgaccct    420

gcaagccaga gctgacagcc ccactgtgcc tgagcccgtg caccgcccac aggacccatg    480

gcacattccc ggtgtgcctg agcccgtgca ccgcccacag gacccgtggc acattcccgg    540

tgtgcctgag cccgtgcacc gcccacagga cccgtggcac attcccggtg tgcctgagcc    600

cgtgcaccgc ccacaggacc cgtggcacat tcccggtgtg cctgagcccg tgcaccgccc    660

acaggacccg tggccttggc ttcagttggt gcctccagcc gagttggcct attgcctgct    720

catgctgctg cttgcacact gcatgaaaca gcaggccaga ccaggacatc cagactttct    780

ccatcgtgag gcctgggcct gcctttctgc agccggaggt ctcgccagcc ctggactcct    840

gctttgggcc acagcaagac ctcgggcgag tggagaggcg gggccaggcc gggcccttgt    900

gggtgctgat gctgcatgtt gtccccgaca cagcgtcctc tccctggtgg acatccccag    960

cggtcaggtg cttccccaag ggcagtgagg ggtgaacatc cagggcctac ctggctgtgc   1020

acgctgcagc cacactgtgg aagctgcccc tccccgagga cccgcctccc ttgctgatgc   1080

caggatctcg gcgcatagac cactctgccc cagcggtcgt cacagaaagg tctctctgtt   1140

cctcacactc agcttcagca taagctgtga ggccagaaaa aaggtcagct cttctagtat   1200

cgtgcagtgc ttaaaaaccg ggagctccag ccgggcgcag tggttcatgc cagtaatccc   1260

agcactttcg gaggccgagg tgggaggatt gcttgaggcc aggagttcaa gaccagcctg   1320

ggcaacacag caagatcctg tctttgtaaa aaaactaacc aaacaggtgc ggtgtgcacc   1380

gagcgcgcct ggcctgatgc cctggcctgt gagctgggga ctcctgggcc ctgtgagccc   1440

ctaggcggca ggcccaggaa cggctgggta ggacagggaa cacctttgcc ccacgtctgg   1500

ctgtgacctc ggtgaaagcc gacaggagag agatgggacc ctcctcctca gtagtggctg   1560

ccagtccctc gttgcaggac agggtcatca taaccataaa taacccttca cgtgtcacct   1620

gcagcttcca ctctttattt ccaaagaatc agtgtcacac atgcagatca c            1671


<210>  654
<211>  1596
<212>  DNA
<213>  Human

<400>  654
tgccccggtc gggcgggact tcctgtgtcg tatttccaag gactccaaag cgaggccggg     60

gactgaaggt gtgggtgtcg agccctctgg cagagggtta acctgggtca aatgcacgga    120

ttctcacctc gtacagttac gctctcccgc ggcacgtccg cgaggacttg aagtcctgag    180

cgctcaagtt tgtccgtagg tcgagagaag gccatggagg tgccgccacc ggcaccgcgg    240

agctttctct gtagagcatt gtgcctattt ccccgagtct ttgctgccga agctgtgact    300

gccgattcgg aagtccttga ggagcgtcag aagcggcttc cctacgtccc agagccctat    360

tacccggaat ctggatggga ccgcctccgg gagctgtttg gcaaagatga acagcagaga    420

atttcaaagg accttgctaa tatctgtaag acggcagcta cagcaggcat cattggctgg    480

gtgtatgggg gaataccagc ttttattcat gctaaacaac aatacattga gcagagccag    540

gcagaaattt atcataaccg gtttgatgct gtgcaatctg cacatcgtgc tgccacacga    600

ggcttcattc gttatggctg gcgctggggt tggagaactg cagtgtttgt gactatattc    660

aacacagtga acactagtct gaatgtatac cgaaataaag atgccttaag ccattttgta    720

attgcaggag ctgtcacggg aagtcttttt aggataaacg taggcctgcg tggcctggtg    780

gctggtggca taattggagc cttgctgggc actcctgtag gaggcctgct gatggcattt    840

cagaagtact ctggtgagac tgttcaggaa agaaaacaga aggatcgaaa ggcactccat    900

gagctaaaac tggaagagtg gaaaggcaga ctacaagtta ctgagcacct ccctgagaaa    960

attgaaagta gtttacagga agatgaacct gagaatgatg ctaagaaaat tgaagcactg   1020

ctaaaccttc ctagaaaccc ttcagtaata gataaacaag acaaggactg aaagtgctct   1080

gaacttgaaa ctcactggag agctgaaggg agctgccatg tccgatgaat gccaacagac   1140

aggccactct ttggtcagcc tgctgacaaa tttaagtgct ggtacctgtg gtggcagtgg   1200

cttgctcttg tctttttctt ttctttttaa ctaagaatgg ggctgttgta ctctcacttt   1260

acttatcctt aaatttaaat acatacttat gtttgtatta atctatcaat atatgcatac   1320

atgaatatat ccacccacct agattttaag cagtaaataa aacatttcgc aaaagattaa   1380

agttgaattt tacagttcgt atattcatgt ggtcctttga aagggtattc tagaaatcac   1440

tggaaagagg agaggaaaga accaggtagg caaatggtct gtgaaaccct tgggtcctgg   1500

aagcagtgtg agtgtaaatg tgtagtgttt ggtttcatct aaataaacaa agatgatttc   1560

tttgacactt gaaataaaat acaaattcaa caaaaa                             1596


<210>  655
<211>  1664
<212>  DNA
<213>  Human

<400>  655
ggtggcgcgg ccgggcccag ctgcggggcg gaggcggagg cggaggagag gcctgcggcg     60

gcagggagcg gcgggactgg gagcgggcgc cggagccgac ccgagccgag ccgagccgag    120

ccgagccgga gcgggcggcg aaggccggcg cggcgagcag caaccatgtc ggtgttcggg    180

aagctgttcg gggctggagg gggtaaggcc ggcaagggcg gcccgacccc ccaggaggcc    240

atccagcggc tgcgggacac ggaagagatg ttaagcaaga aacaggagtt cctggagaag    300

aaaatcgagc aggagctgac ggccgccaag aagcacggca ccaaaaacaa gcgcgcggcc    360

ctccaggcac tgaagcgtaa gaagaggtat gagaagcagc tggcgcagat cgacggcaca    420

ttatcaacca tcgagttcca gcgggaggcc ctggagaatg ccaacaccaa caccgaggtg    480

ctcaagaaca tgggctatgc cgccaaggcc atgaaggcgg cccatgacaa catggacatc    540

gataaagttg atgagttaat gcaggacatt gctgaccagc aagaacttgc agaggagatt    600

tcaacagcaa tttcgaaacc tgtagggttt ggagaagagt ttgacgagga tgagctcatg    660

gcggaattag aagaactaga acaggaggaa ctagacaaga atttgctgga aatcagtgga    720

cccgaaacag tccctctacc aaatgttccc tctatagccc taccatcaaa acccgccaag    780

aagaaagaag aggaggacga cgacatgaag gaattggaga actgggctgg atccatgtaa    840

tggggtccag cgctggctgg gcccagacag actgtggtgg cctgcgcagc gagcaggcgt    900

gtgcgtgtgt ggggcaggca ggatgtggtg caggcaggtt ccatcgcttt cgactctcac    960

tccaaagcag tagggccgcg ttgctgctca ctctctgcat agcatggtct gcacctggga   1020

gatgggcggg gggagggggg cgggcggggt gggaagtgcc tgctgtttat aatgttgaat   1080

ttctgtaaaa taaactgtat ttgcaaatcc aacattgagc ttctggacta cgctgactcc   1140

actgctgaat cctcaatgga aagggtcgac tggttgcagt tgaaatgacc tgaaatgtag   1200

cctctgtcct tgtaagtcag ttgacttgcc gcacatctct ttgtgtactt gtacggtact   1260

ggcagaaaag tcatttttca aaagccatag gcttttcctt gcccttagct gtaataatgc   1320

atctgatttt gatttcctcc agagctgtgt ttctgtccat cacctgtgta ttggccctgt   1380

gtttaccact ctggcccact cctcaccccc ttgctcccct ggtcttctgg agtttgtgac   1440

attgatttga aatggatggt gttctcttga gagcaagtga gattgttaga attaagttcc   1500

aactatacag ttttctaaca tagctataag gtccttgttg ctgtttgtga taactgatag   1560

ataactcatt ggaaacgtgc atacatttat attcagatga aattatggtt tgcactgtct   1620

attaaatatc tcgattaatt ttcatacaaa aaaaaaaaaa aaaa                    1664


<210>  656
<211>  5473
<212>  DNA
<213>  Human

<400>  656
ggaggtgcga gcccctgccg ggtcccccct gcgccggacc atgtattcgg cccacaggcc     60

cctgatgccc gcgtccagcg cggcctcccg tggcctcggc atgttcgtgt ggacgaatgt    120

ggaacctcgc tctgtggctg tgttcccttg gcactcctta gtccccttcc tggcacccag    180

ccagcctgac ccctccgtgc agccgagcga ggcccagcaa cctgccagcc acccagtggc    240

ctccaaccag agcaaagaac ctgctgagtc ggcagctgtt gctcatgaac ggccaccagg    300

tgggacaggg agtgctgacc ctgagcggcc ccctggagcc acatgccctg agagcccagg    360

acccggaccc ccacaccctt tgggggtggt ggaatctggt aagggtccgc ctcccaccac    420

ggaggaggag gcctccggcc ccccaggaga gccccggctg gacagtgaga cagagagtga    480

ccatgatgat gccttcctct ccatcatgtc tcctgagatc cagttgcctc taccgcccgg    540

aaaacgtcgg acccagtccc tcagtgccct acccaaggaa cgggactcat cttctgagaa    600

ggatggacgc agccccaaca agcgggagaa ggaccacatc cggcggccca tgaatgcctt    660

catgatcttc agcaagcggc accgggccct ggtccaccag cgtcatccca accaggacaa    720

ccggaccgtc agcaagatcc tgggcgagtg gtggtatgcc ctggggccca aggagaagca    780

gaagtaccac gacctggcct tccaggtgaa ggaggcccac ttcaaggccc acccagattg    840

gaagtggtgc aacaaggacc gaaagaagtc cagctcagag gccaagccca cgagcctggg    900

gctggcagga gggcacaagg agacgcggga gcggagcatg tcggagacgg gcactgctgc    960

tgcccctggg gtgtcctctg agctcctgtc cgttgcagcc cagacactcc tgagctcaga   1020

caccaaggct ccggggagca gctcctgtgg ggcagaacgg ctacacacag ttgggggacc   1080

tggctcagcc cggccccgag ctttctccca cagcggggta cacagcctgg acggcggaga   1140

agtagacagt caggcgctac aggaactgac gcagatggtg tctggccctg catcgtactc   1200

tggcccaaag ccttctaccc agtatggagc tccaggaccc tttgcagccc ctggtgaggg   1260

aggtgccttg gcggccactg ggcggccccc gctgctgccc acccgagctt ctcgttctca   1320

gcgtgcggcc agtgaggaca tgacgagtga tgaggagcgc atggtcatct gtgaggagga   1380

aggggatgat gatgtcattg ctgacgatgg cttcggcacc actgacattg atctcaagtg   1440

caaggagcgg gtgaccgaca gcgagagtgg ggacagctct ggggaggacc cagagggcaa   1500

caagggcttt ggtcggaagg tgttttcacc tgtgatccgt tcctccttta cccactgccg   1560

ccccccactg gaccctgagc ccccagggcc cccggatcct cctgtagcct ttggcaaagg   1620

ctatggttcc gccccatcct cctctgcgtc ctcgcctgct tcctcctcag cctcggcagc   1680

cacctccttc tcactgggct caggaacctt caaggcccag gagtctggtc agggcagcac   1740

agcgggcccc ctacggcccc caccccctgg ggctgggggt ccagcgacac cttccaaggc   1800

aacccggttc ctcccaatgg atcctgccac cttccggcgc aagagacccg aaagtgtggg   1860

tggcctggag ccaccaggcc cctcagtcat cgcggcccct cccagcggag gaggaaacat   1920

cctgcagaca ctggtgctgc ccccaaacaa ggaggagcaa gagggcggcg gagccagagt   1980

gccctccgcc cccgccccat cactggccta tggggcccca gcagctcccc tgtcccgtcc   2040

tgccgccacc atggtcacca atgtggtgcg gcctgtcagc agcactcctg tgcccatcgc   2100

ctctaagccc ttccccacct ctggccgggc tgaggcgtct ccaaatgaca cagcaggtgc   2160

caggactgaa atgggcactg ggtctcgggt gcctgggggc tccccgctgg gtgtcagctt   2220

agtgtattcg gacaagaagt cggcagcagc cacctcacca gccccacact tggtggctgg   2280

acccctgctg ggcactgtgg ggaaggcgcc tgccactgtc actaacctac tggtgggcac   2340

cccggggtat ggggcccctg cgccccctgc tgtccagttc attgcccagg gggcccctgg   2400

tggtgggacc actgcgggct caggagcagg tgctgggagt ggccccaatg ggccagtacc   2460

cctgggcatc ctgcaaccag gtgccctggg caaggctggg ggaatcaccc aggtacagta   2520

catcctgccc acgctgcccc agcagcttca ggtggcacct gccccagcac cagcccctgg   2580

gaccaaggca gcggctccca gcggccctgc acccaccacc agcatccgtt tcaccctccc   2640

accgggcact tccaccaacg gcaaagtcct ggctgccact gcacccactc ctggcatccc   2700

catcctgcag tctgtaccct ccgccccacc ccccaaagcc cagtcagttt ctcccgtgca   2760

ggccccgccc ccgggtggct cagcccagct gctgcctggg aaggtcctag tgcctctggc   2820

cgcccctagc atgtcagtgc ggggtggagg ggccggccag ccactgccac tggtgagccc   2880

gcccttctca gtacctgtgc agaatggtgc ccagcccccc agcaagatca tccagctgac   2940

cccggtgcct gtgagcacac ccagcggcct ggtgccgccc ctgagcccag ccacactccc   3000

tggacccacc tctcagcctc agaaggtcct gttgccctcc tccaccagaa tcacctatgt   3060

gcagtcagcg ggcgggcacg cgctgcccct gggtaccagc cctgcgtcca gccaggctgg   3120

aacagtcacc tcgtacgggc ccacgagctc tgtagctcta ggcttcacct cgctggggcc   3180

cagcggcccc gccttcgtgc agcccctgct ctcagcaggc caagccccac tgctggctcc   3240

cggtcaggtg ggcgtgtcac ctgtgcccag tccccagctg ccgcctgcct gtgcagcccc   3300

cggaggtcct gtcataacag cattttactc tggcagccct gcacccacct cctcagcacc   3360

cctggcccag ccatcccagg cccccccaag cctggtctac actgtggcca ccagcacaac   3420

cccacctgca gccaccattc tgcccaaggg cccgccagcc cctgccactg ccaccccagc   3480

cccgactagc cctttcccca gcgccacagc aggttccatg acctacagct tagtggcccc   3540

caaggcccag cggcccagcc cgaaggcccc ccagaaagtg aaggcagcca tcgccagcat   3600

tcccgtgggg tcctttgagg caggtgcctc tgggcggcct ggccctgcac cccggcagcc   3660

tctggagcct ggcccagtcc gagagccaac tgccccagag tctgagcttg aggggcagcc   3720

cacaccacca gcccctccac ccctgccaga gacctggact cccacggccc ggagcagccc   3780

cccactgccc ccacctgctg aggagcggac cagcgccaag ggccctgaga ccatggccag   3840

caaattcccc agctcatctt cagactggcg cgtccctggg cagggcctgg agaatcgtgg   3900

ggagcctccc actcctccca gcccggcccc agctccagct gtagcccctg gtggcagcag   3960

cgagagcagc agtgggcggg cagccgggga caccccggag cgcaaggagg cggctggtac   4020

tggcaagaag gtgaaggtgc ggcccccgcc cctgaagaag acctttgact ctgtggacaa   4080

cagggtcctg tcagaagtgg acttcgaaga gcgctttgct gagttgcctg agtttcggcc   4140

tgaggaggtg ctgccctccc ccaccctgca gtctctggcc acctcacccc gggccatcct   4200

gggctcttac cgcaagaaga ggaagaactc cacggacctg gattcagcac ccgaggaccc   4260

cacctcgccc aagcgcaaga tgagaagacg ctccagctgc agctcggagc ccaacacccc   4320

caagagtgcc aagtgcgagg gggacatctt cacctttgac cgtacaggta cagaagccga   4380

ggacgtgctt ggggagctag agtatgacaa ggtgccatac tcctccctgc ggcgcaccct   4440

ggaccagcgc cgggccctgg tcatgcagct ctttcaggac catggcttct tcccgtcagc   4500

ccaggccaca gccgccttcc aggcccgcta tgcagacatc tttccctcca aggtttgtct   4560

gcagttgaag atccgtgagg tgcgccagaa gatcatgcag gctgccactc ccacggagca   4620

gccccctgga gctgaggctc ctctccctgt accgcccccc actggcaccg ctgctgcccc   4680

tgcccccact cccagccccg cagggggccc tgaccccacc tcacccagct cggactctgg   4740

cacggcccag gctgccccgc cactgcctcc acccccagag tcggggcctg gacagcctgg   4800

ctgggagggg gctccccagc cctccccccc acccccaggt ccctccacag ctgccacagg   4860

caggtgaggg acccctgaga agatgccagg acttatagta ccccctcagg acatggacag   4920

tatgtggggg caggaaggtt atctcctccc gggtaaagcc atttcgtcct ctccagtttg   4980

gggcggaatg aggcctgctc ctcttgtaaa tacccccttc cctcgaagct ccctcccggt   5040

gctggggggc agctgagggg ctgcaggggc agtctccctc ctccaagccc ctgtacataa   5100

cctggagcgt gtgaccttca gagcttttca ctttatgcaa aatggctcct gtgagggctg   5160

caagctggag ggtggtgcag gccttgggcc acagggaggc gcctgtggaa tagggggagt   5220

tcatgcaccc cttttttccc cagaggggct ggactcaggt tagtttgggg gtgggggctc   5280

ctgcactttg ccacaggcac ggggagggtt ttctcctcac cccctctgcc ctcccaactt   5340

gggttgtact ttctaagaag gtgattcccc ctgcccttgc ccccttcccc agaacaaaac   5400

atgttgatca tgtgcaatat ttcttactgt gccgagaagc cgcaatgagc gagattaaag   5460

ctgtttaaca cac                                                      5473


<210>  657
<211>  3036
<212>  DNA
<213>  Human

<400>  657
gggggagccc ctgcaagttt cccgggccgc gcgccgcgct cgctcgcctc ccagcccgcg     60

gcccgagccg ccgccgcgcc cgccatgccc tcggccaaac aaaggggctc caagggcggc    120

cacggcgccg cgagcccctc ggagaagggt gcccacccgt cgggcggcgc ggatgacgtg    180

gcgaagaagc cgccgccggc gccgcagcag ccgccgccgc cgcccgcgcc gcacccgcag    240

cagcacccgc agcagcaccc gcagaaccag gcgcacggca agggcggcca ccgcggcggc    300

ggcggcggcg gcggcaagtc ctcctcctcc tcctccgcct ccgccgccgc tgccgccgcc    360

gccgcctcgt cctcggcgtc ctgctcgcgc aggctcggca gggcgctcaa ctttctcttc    420

tacctcgccc tggtggcggc ggccgctttc tcgggctggt gcgtccacca cgtcctggag    480

gaggtccagc aggtccggcg cagccaccag gacttctccc ggcagaggga ggagctgggc    540

cagggcttgc agggcgtcga gcagaaggtg cagtctttgc aagccacatt tggaactttt    600

gagtccatct tgagaagctc ccaacataaa caagacctca cagagaaagc tgtgaagcaa    660

ggggagagtg aggtcagccg gatcagcgaa gtgctgcaga aactccagaa tgagattctc    720

aaagacctct cggatgggat ccatgtggtg aaggacgccc gggagcggga cttcacgtcc    780

ctggagaaca cggtggagga gcggctgacg gagctcacca aatccatcaa cgacaacatc    840

gccatcttca cagaagtcca gaagaggagc cagaaggaga tcaatgacat gaaggcaaag    900

gttgcctccc tggaagaatc tgaggggaac aagcaggatt tgaaagcctt aaaggaagct    960

gtgaaggaga tacagacctc agccaagtcc agagagtggg acatggaggc cctgagaagt   1020

acccttcaga ctatggagtc tgacatctac accgaggtcc gcgagctggt gagcctcaag   1080

caggagcagc aggctttcaa ggaggcggcc gacacggagc ggctcgccct gcaggccctc   1140

acggagaagc ttctcaggtc tgaggagtcc gtctcccgcc tcccggagga gatccggaga   1200

ctggaggaag agctccgcca gctgaagtcc gattcccacg ggccgaagga ggacggaggc   1260

ttcagacact cggaagcctt tgaggcactc cagcaaaaga gtcagggact ggactccagg   1320

ctccagcacg tggaggatgg ggtgctctcc atgcaggtgg cttctgcgcg ccagaccgag   1380

agcctggagt ccctcctgtc caagagccag gagcacgagc agcgcctggc cgccctgcag   1440

gggcgcctgg aaggcctcgg gtcctcagag gcagaccagg atggcctggc cagcacggtg   1500

aggagcctgg gcgagaccca gctggtgctc tacggtgacg tggaggagct gaagaggagt   1560

gtgggcgagc tccccagcac cgtggaatca ctccagaagg tgcaggagca ggtgcacacg   1620

ctgctcagtc aggaccaagc ccaggccgcc cgtctgcctc ctcaggactt cctggacaga   1680

ctttcttctc tagacaacct gaaagcctca gtcagccaag tggaggcgga cttgaaaatg   1740

ctcaggactg ctgtggacag tttggttgca tactcggtca aaatagaaac caacgagaac   1800

aatctggaat cagccaaggg tttactagat gacctgagga atgatctgga taggttgttt   1860

gtgaaagtgg agaagattca cgaaaaggtc taaatgaatt gcgtgtgcag ggcgcggatt   1920

taaagtccaa tttctcatga ccaaaaaatg tgtggttttt tcccatgtgt cccctacccc   1980

ccaatttctt gtcccctctt aaagagcagt tgtcaccacc tgaacaccaa ggcattgtat   2040

tttcatgccc agttaactta tttacaatat ttaagttctc tgcttctgca tttggttggt   2100

ttcctgaagc gcagcccctg tgaataacag gtggcttttc atggatgtct ctagtcagag   2160

aaaaatgata aaggcttaaa ttgaggatta acagaagcag attaacctca gaaatcctgt   2220

ctggctggca gatttcaagt aaaaaaaaaa aaaaggtggg ttggggggac ccttttcttt   2280

ctagttgtct ttaaggaaaa ttaattttac tttttttttt gttctggccg aaatttttat   2340

gagatatctc tcacttgtct tccactttga accggttaaa gctcatagct gtcagctctg   2400

aatgaggagg ggagaagccc ctgggtcttt ctttgaaagg aatccgctgc ttgagggctg   2460

cctccctcat ggtgtgcgtg tcgtttctct tcctgacgca tcttgtgata tcagaggtaa   2520

ctatgcaaag catccaggcg gttctgaatg tgaagcacta cacccagcag agtcccggtg   2580

ccctctgtcc ccactgccgg cccatgttct ctctccggag gtcaccaagg aatgcacagg   2640

tttcgactac cagaaagggg agtccttggg ttctttcaaa aaattcgtga ggagagctgt   2700

ctacagtgga atagggggtc tccctgggga atgcaggcca agtcctttta ttttaacatg   2760

atgtccatga agaggtttgc cgtctgggca gccctgtcgg caaggagcgt gcatactgcg   2820

tttgtgtaat tgtttgctgt atctcccttc cctctgagct gtattgttct ttaatggctg   2880

tcttgccctt ccaaaaaaaa ttgaaaaaaa aaaaaaaaaa aaaacccgaa aagtaaaaaa   2940

aaaaaaaaaa agttttgttt agtttactgt gaaatgaact gtatggctta tttacagtat   3000

ttttaattct taataaacac ttgagctttg ttatga                             3036


<210>  658
<211>  6733
<212>  DNA
<213>  Human

<400>  658
attgctactg attacatgga tatctttagg gaagcagaaa atgattgctg aacacatgcc     60

ttgtgttttg atgattgcat taaaagtccc ccagcgggat ggcatttatt ggctctcaga    120

gcttttctta gattaaattt caggcagcca gtacaaggag aaacatcata acctgtatcc    180

aacagcatat gtgcagctaa agagtaatct taatcaagtc cttctaggct gtgctaaata    240

aacgagggtt ttcagcaaga ccccagactt ttattttgaa gtggagtagc agctgttggc    300

tattgcggtg cagagctgca gcgaggcctg ggtcacacag tgctccgggt gtctgcaggc    360

tgcaggccga gcccagtggc gcaggcactg agctgtactt atttgctgtg ctatttgacc    420

tcttggtttc agagagctcc ctggaccatc taatggctat gggagatgat aaaagcttcg    480

atgatgaaga atcagtggat ggaaataggc catcatcagc tgcatcagcc ttcaaggttc    540

ctgcacctaa aacatccgga aatcctgcca acagtgcaag gaagcctggt tcagcaggtg    600

gccctaaggt tggaggtgct tctaaggaag gaggtgctgg agcagttgat gaagatgatt    660

ttataaaagc ttttacagat gtcccttcta ttcagattta ttctagtcga gaactcgaag    720

aaacattaaa taaaatcagg gaaattttgt cagatgataa acatgactgg gatcagcgtg    780

ccaatgcact gaagaaaatt cgatcactgc ttgttgctgg agctgcacag tatgattgct    840

tttttcaaca tttacgattg ttggatggag cacttaaact ttcagctaag gatcttagat    900

cccaggtggt tagagaagct tgtattactg tagcccacct ttcaacagtt ttgggaaaca    960

agtttgatca tggcgctgaa gccattgtac ctacactttt taatctcgtc cccaatagtg   1020

caaaagtcat ggcaacttct ggatgtgcag caatcagatt tatcattcgg catactcatg   1080

tacccagact tataccttta ataacaagca attgcacatc aaaatcagtt cccgtgagga   1140

gacgttcatt tgaattttta gatttattgt tgcaagagtg gcagactcat tcattggaaa   1200

gacatgcagc cgtcttggtt gaaactatta aaaagggaat tcatgatgct gacgctgagg   1260

ccagagtgga ggcaagaaag acatacatgg gtcttagaaa ccactttcct ggtgaagctg   1320

aaacattata taattccctt gagccatctt atcagaagag tcttcaaact tacttaaaga   1380

gttctggcag tgtagcatct cttccacaat cagacaggtc ctcatccagc tcacaggaaa   1440

gtctcaatcg ccctttttct tccaaatggt ctacagcaaa tccatcaact gtggctggaa   1500

gagtatcagc aggcagcagc aaagccagtt cccttccagg aagcctgcag cgttcacgaa   1560

gtgacattga tgtgaatgct gctgcaggtg ccaaggcaca tcatgctgct ggacagtctg   1620

tgcgaagcgg gcgcttaggt gcaggtgccc tgaatgcagg ttcctatgcg tcactagagg   1680

atacttctga caagctggat ggaacagcat ctgaagatgg ccgggtgaga gcaaaacttt   1740

cagcaccact tgctggcatg ggaaatgcca aggcagattc tagaggaaga agtcgaacaa   1800

aaatggtgtc tcaatcacag cctggtagcc ggtctgggtc tccaggaaga gttctgacca   1860

caacagccct gtccactgtg agctctggtg ttcaaagagt cctggtcaat tcagcctcag   1920

cacaaaaaag aagcaagata ccacggagcc agggctgtag cagagaggct agtccatcta   1980

ggctttcagt ggcccgaagc agtcgtattc ctcgaccaag tgtgagtcaa ggatgcagcc   2040

gggaagctag tcgggagagc agcagagaca caagtcctgt tcgctctttt cagcccctcg   2100

cctccagaca ccattccaga tcaactggtg ccctctacgc ccccgaagtg tatggggcct   2160

caggtccagg ttatgggatc agccaatcaa gtcgactgtc gtcttctgtt agtgccatgc   2220

gagtcctgaa cacaggttct gatgtggagg aggcggtggc agatgccttg aaaaaaccag   2280

ctcgaagaag atatgaatca tatggaatgc attcagatga tgacgccaac agcgatgcat   2340

ctagtgcttg ttcagaacgc tcctatagtt ctcgaaatgg tagtattcct acatatatga   2400

ggcagacgga agatgtggca gaagtcctca atagatgtgc tagttccaat tggtcagaaa   2460

ggaaagaagg cctcctaggt ctgcagaact tattaaaaaa tcagagaaca ctaagtcgag   2520

ttgaactgaa aagattatgt gaaattttca caagaatgtt tgctgaccct catggcaaga   2580

gagtattcag catgtttttg gagactctag tggatttcat acaagtccac aaagatgatc   2640

ttcaagattg gttgtttgta ctgctgacac aactactaaa aaaaatgggt gctgatttgc   2700

ttggatctgt tcaggcaaaa gttcagaaag cccttgatgt tacaagagag tcttttccaa   2760

atgatcttca gttcaatatt ctaatgagat ttacagttga tcagacccag acaccaagct   2820

taaaggtgaa ggttgctatc cttaaataca tagaaactct ggccaaacag atggatccag   2880

gagattttat aaattccagt gaaactcgcc tagcagtgtc tcgggtcatc acttggacaa   2940

cagaacccaa aagttctgat gttcggaagg cagcacagtc agtgctgatt tcattatttg   3000

aactcaatac cccagagttt acaatgttat taggagcttt accaaaaact tttcaggatg   3060

gtgctaccaa gcttcttcat aatcaccttc gaaacactgg caatggaacc cagagttcca   3120

tggggagtcc tttgacaaga ccaacaccac gatcaccagc taactggtcc agtcctctta   3180

cttctcctac caatacatca cagaatactt tatctccaag tgcatttgat tatgacacag   3240

aaaatatgaa ctctgaagat atttatagct ctcttagagg tgtcactgaa gcaatccaga   3300

atttcagctt ccgtagccaa gaagatatga atgagccatt gaaaagggat tctaaaaaag   3360

atgatggcga ttcaatgtgt ggtggtcctg ggatgtctga cccaagagca ggaggtgatg   3420

ctactgactc aagtcaaaca gctcttgata ataaagcttc attgctccat tcaatgccta   3480

ctcactcctc tccacgctct cgagactata atccatataa ctattcagat agcatcagtc   3540

ccttcaacaa gtctgccctc aaggaagcca tgtttgatga tgatgctgac cagtttcctg   3600

acgatctttc cctagatcat tctgacctag ttgcagagtt gttgaaggag ctgtctaacc   3660

ataatgagcg tgtagaagaa agaaaaattg ccctctatga acttatgaaa ctgacacagg   3720

aagaatcttt tagtgtttgg gatgaacact tcaaaacaat attgctttta ttgcttgaaa   3780

cgcttggaga taaagagcct acaatcaggg ctttggcatt aaaggtttta agagaaatcc   3840

taaggcatca accagcaaga tttaaaaact atgcagaatt gactgtcatg aaaacattgg   3900

aagcacataa agatcctcat aaggaggtgg tgagatctgc tgaggaagcg gcatcagtgt   3960

tggccacttc aattagtcca gagcagtgca tcaaagtgct ttgtcctatc attcaaactg   4020

cagactaccc aattaatctg gctgcaatca aaatgcaaac aaaagtgata gagagagtgt   4080

ccaaggaaac cctaaacctg cttttgccag agattatgcc aggtctaata cagggttatg   4140

ataattcaga gagcagtgtt cggaaagctt gtgtcttctg cctggtggct gttcatgcgg   4200

taattggtga tgaactaaaa ccacatctca gtcaacttac tggcagtaaa atgaagctac   4260

tgaatcttta catcaaacgt gcacaaacag gttctggagg agctgatccc actactgatg   4320

tttctggaca aagttagtga agctcatcac agcgaaccag gtctctcaaa agaaaggaca   4380

gatagaccac cctcatcaat gaaaggaagt tctcaaacac atcctttgga acttactatt   4440

gtttcccagt tttagttttt tgtttcgttt cgttttgtat tttctgtaac agaggactat   4500

cctcagtctg catgtaactt ttatgatagt tattccaaat tcaagaagaa gcagtattaa   4560

catcaattga tcgacacaaa gtaattttta atttaattca tcatttcaca tgtttgtact   4620

ttgtcttccc attaaccttt gccagtgtta tgattgtata aattttttta aatgctggtt   4680

aaacaggaat gcttaaagct ttaaaagttt aacagtctaa aacatttttg cttttattca   4740

actgcagaat aatattttta ttgctacttt gagttttgtt tcgtatcatg tcctatgcta   4800

gaaatattta aatgatgtga aacaaagcag gactaatttg aactacagct ggactccgtt   4860

tgtgtgatgg tgatacatgt cattagttgc aacttctttg gggtgatcta tagtttgaaa   4920

actaaaacct caaagacaga tgttacagaa tcagccagtt ctgtaaaact gatattgtct   4980

attggttatt gatcttgcca tctttattta aaaccatgtc ccttctatga tcccttaaga   5040

aagctgcacc aaatcatctg cctgtttttt cttgatactt actgaaatag aaggttttat   5100

tgcagggttt attttggttt gtttatatct ttgttgtgaa tgatgctttt ttgtatttat   5160

taatatcaaa ttcacttatg aataaacttg ataatggaaa cggacaaaaa aaatcaagtg   5220

cgtgtgtgtc cttgaccgtc ttctgtttct cacgtaataa acaaattatc gagacatggg   5280

agtgaccagc accttttctt taaatggtgg aacctggttt ccttttacca tgaaattgtc   5340

ttacttgaaa atattgatcc tgatgagaga gaagatggtg ccaaggctgt ctttgtataa   5400

tgggctcaaa ttctctacct cttcagggct aatactttta actgagctgc tgcctatagt   5460

gtcttttgga aaactactta aagggtgatt ttctgttact ttttagcaaa tttttttaat   5520

cacctcttgc tacacccatt cttttcatgt gcagccgact caaaaattac cagttttggt   5580

gaaaggctaa attagataat ttggaaccag gatactaatg atttctcatc tttacttttt   5640

tttaatccta atataaagtg aatttgattg aaaaggcaaa tagctattag ggaagcagtt   5700

tgccattgtt gcagagttat ctgtactttg tttaactgaa aaaaatgtag aaatatatgt   5760

aaagaattta agacaagagt actgaatgga tgatttgtca taggctttcc cctttctttc   5820

tgttctagca gcaggaaaag tttctctata tcctctccct ctacctgtaa caattttgtt   5880

ttctactgtt aattacattg tgtatttata gttctatgct tactgttgtg catatactgg   5940

caataaaact gtacataaca ttacttgaaa aagttaataa tgtatatcag tttttctgtc   6000

tcactgtgta acaagtcact cagttttatt ttaactttag acggtcttgt atcagtggtg   6060

gtctcttgaa ttttgtaagt tcatctgagg agaaaagatt tttcaggtgt agctaccaca   6120

atcaaaggta tatagctaca tacgcatgta tatattacag cttatctgta agaagaaaat   6180

gcattttaaa cacaactctt ctcagtagca ttttatgacc tttggatatg tttgtaatca   6240

tttcgaatca aaatattgat ttaattttga cctctggttt aagatactgc tttaactact   6300

gttgacaacc aagtagagtg acttaagctg aacagtaact aactggaaaa ttagataagc   6360

acctggcatc taatggcagg caggcactca agaaatgaat taactacata atggaaaagt   6420

atggtttaat gtgtccaaat gaaagctagt agatgtaaac atggaaaaat tgtgtttaca   6480

attttataat ctcagttgat aagactataa gaaagctgat tatttaaatc actatataca   6540

atacaccctt aatttgttca ttccagaaac atactgagat gtcagctact taaaaatggt   6600

cacaaaaagc tactgtttat atttttcctc ctgctattct ctcccaaatt aattattaat   6660

aagtgttgtt catttactgc actgctgaga actaattaaa attatatatt ccagattgta   6720

aaaaaaaaaa aaa                                                      6733


<210>  659
<211>  2471
<212>  DNA
<213>  Human

<400>  659
agaaagcgag cagccaccca gctccccgcc accgccatgg tccccgacac cgcctgcgtt     60

cttctgctca ccctggctgc cctcggcgcg tccggacagg gccagagccc gttgggctca    120

gacctgggcc cgcagatgct tcgggaactg caggaaacca acgcggcgct gcaggacgtg    180

cgggagctgc tgcggcagca ggtcagggag atcacgttcc tgaaaaacac ggtgatggag    240

tgtgacgcgt gcgggatgca gcagtcagta cgcaccggcc tacccagcgt gcggcccctg    300

ctccactgcg cgcccggctt ctgcttcccc ggcgtggcct gcatccagac ggagagcggc    360

gcgcgctgcg gcccctgccc cgcgggcttc acgggcaacg gctcgcactg caccgacgtc    420

aacgagtgca acgcccaccc ctgcttcccc cgagtccgct gtatcaacac cagcccgggg    480

ttccgctgcg aggcttgccc gccggggtac agcggcccca cccaccaggg cgtggggctg    540

gctttcgcca aggccaacaa gcaggtttgc acggacatca acgagtgtga gaccgggcaa    600

cataactgcg tccccaactc cgtgtgcatc aacacccggg gctccttcca gtgcggcccg    660

tgccagcccg gcttcgtggg cgaccaggcg tccggctgcc agcggcgcgc acagcgcttc    720

tgccccgacg gctcgcccag cgagtgccac gagcatgcag actgcgtcct agagcgcgat    780

ggctcgcggt cgtgcgtgtg tgccgttggc tgggccggca acgggatcct ctgtggtcgc    840

gacactgacc tagacggctt cccggacgag aagctgcgct gcccggagcg ccagtgccgt    900

aaggacaact gcgtgactgt gcccaactca gggcaggagg atgtggaccg cgatggcatc    960

ggagacgcct gcgatccgga tgccgacggg gacggggtcc ccaatgaaaa ggacaactgc   1020

ccgctggtgc ggaacccaga ccagcgcaac acggacgagg acaagtgggg cgatgcgtgc   1080

gacaactgcc ggtcccagaa gaacgacgac caaaaggaca cagaccagga cggccggggc   1140

gatgcgtgcg acgacgacat cgacggcgac cggatccgca accaggccga caactgccct   1200

agggtaccca actcagacca gaaggacagt gatggcgatg gtatagggga tgcctgtgac   1260

aactgtcccc agaagagcaa cccggatcag gcggatgtgg accacgactt tgtgggagat   1320

gcttgtgaca gcgatcaaga ccaggatgga gacggacatc aggactctcg ggacaactgt   1380

cccacggtgc ctaacagtgc ccaggaggac tcagaccacg atggccaggg tgatgcctgc   1440

gacgacgacg acgacaatga cggagtccct gacagtcggg acaactgccg cctggtgcct   1500

aaccccggcc aggaggacgc ggacagggac ggcgtgggcg acgtgtgcca ggacgacttt   1560

gatgcagaca aggtggtaga caagatcgac gtgtgtccgg agaacgctga agtcacgctc   1620

accgacttca gggccttcca gacagtcgtg ctggacccgg agggtgacgc gcagattgac   1680

cccaactggg tggtgctcaa ccagggaagg gagatcgtgc agacaatgaa cagcgaccca   1740

ggcctggctg tgggttacac tgccttcaat ggcgtggact tcgagggcac gttccatgtg   1800

aacacggtca cggatgacga ctatgcgggc ttcatctttg gctaccagga cagctccagc   1860

ttctacgtgg tcatgtggaa gcagatggag caaacgtatt ggcaggcgaa ccccttccgt   1920

gctgtggccg agcctggcat ccaactcaag gctgtgaagt cttccacagg ccccggggaa   1980

cagctgcgga acgctctgtg gcatacagga gacacagagt cccaggtgcg gctgctgtgg   2040

aaggacccgc gaaacgtggg ttggaaggac aagaagtcct atcgttggtt cctgcagcac   2100

cggccccaag tgggctacat cagggtgcga ttctatgagg gccctgagct ggtggccgac   2160

agcaacgtgg tcttggacac aaccatgcgg ggtggccgcc tgggggtctt ctgcttctcc   2220

caggagaaca tcatctgggc caacctgcgt taccgctgca atgacaccat cccagaggac   2280

tatgagaccc atcagctgcg gcaagcctag ggaccagggt gaggacccgc cggatgacag   2340

ccaccctcac cgcggctgga tgggggctct gcacccagcc ccaaggggtg gccgtcctga   2400

gggggaagtg agaagggctc agagaggaca aaataaagtg tgtgtgcagg gaaaaaaaaa   2460

aaaaaaaaaa a                                                        2471


<210>  660
<211>  4090
<212>  DNA
<213>  Human

<400>  660
tcactccgcc ccttctcgtg cacgcgcccg gagcccgcaa ctctcgcgag agaagcgaga     60

tttattccta cgtaccgggc cgtgctgctt atggcggcgc tggagagggg gcgctgagct    120

gttgggtatg aagtgtaaca gaacagactt taccacctga aactgctgct tcaagttcag    180

atcaggcaag gaacaaacct cgtaacaact aacaagacca aagaagagta cacttaagtt    240

gaagacacaa cacttgatct gaaacaagaa gtttgtgcct actcaacagc tttgaaagag    300

cacttcccaa cgctgctagt agtctttgtt ttcttcagtg ctgtactgtg agattgcccg    360

gtacagcagc agttgtattc tttattagct tggtagatca ttttctctcg ctcttttttt    420

taatactagc aactttcatc ctttgaaacg tgtgctgaaa aagaagaatc agcaaatact    480

actgaaagtg caatatttga gtatcactgc gagatgagct ttgatccaaa ccttctccac    540

aacaatggac ataatgggta ccctaatggt acttcagcag cactgcgtga aactggggtt    600

attgaaaaac tgttaacctc ttacggattt attcagtgtt cagaacgtca agctagactt    660

ttcttccact gttcacagta taatggcaac ctgcaagact taaaagtagg agatgatgtt    720

gaatttgaag tatcatcgga ccgacggact gggaaaccca ttgctgttaa actggtgaag    780

ataaaacaag aaatcctccc tgaagaacga atgaatggac aagaagtgtt ttatctgact    840

tacacccctg aagatgtcga agggaacgtt cagctggaaa ctggagataa aataaacttt    900

gtaattgata acaataaaca tactggtgct gtaagtgctc gcaacattat gctgttgaaa    960

aagaaacaag cccgctgtca gggagtagtt tgtgccatga aggaggcatt tggctttatt   1020

gaaagaggtg atgttgtaaa agagatattc tttcactata gtgaatttaa gggtgactta   1080

gaaaccttac agcctggcga tgatgtggaa ttcacaatca aggacagaaa tggtaaagaa   1140

gttgcaacag atgtcagact attgcctcaa ggaacagtca tttttgaaga tatcagcatt   1200

gaacattttg aaggaactgt aaccaaagtt atcccaaaag tacccagtaa aaaccagaat   1260

gacccattgc caggacgcat caaagttgac tttgtgatcc ctaaagaact tccctttgga   1320

gacaaagata cgaaatccaa ggtgaccctg ctggaaggtg accatgttag gtttaatatt   1380

tcaacagacc gacgtgacaa attagagcga gcaaccaata tagaagttct gtcaaataca   1440

tttcagttca ctaatgaagc ccgagaaatg ggtgtgattg ctgccatgag agatggtttt   1500

ggtttcatca agtgtgtgga tcgtgatgtt cgtatgttct tccacttcag tgaaattctg   1560

gatgggaacc agctccatat tgcagatgaa gtagagttta ctgtggttcc tgatatgctc   1620

tctgctcaaa gaaatcatgc tattaggatt aaaaaacttc ccaagggcac ggtttcattt   1680

cattcccatt cagatcaccg ttttctgggc acggtagaaa aagaagccac tttttccaat   1740

cctaaaacca ctagcccaaa taaaggcaaa gagaaggagg ctgaggatgg cattattgct   1800

tatgatgact gtggggtgaa actgactatt gcttttcaag ccaaggatgt ggaaggatct   1860

acttctcctc aaataggaga taaggttgaa tttagtatta gtgacaaaca gaggcctgga   1920

cagcaggttg caacttgtgt gcgactttta ggtcgtaatt ctaactccaa gaggctcttg   1980

ggttatgtgg caactctgaa ggataatttt ggatttattg aaacagccaa tcatgataag   2040

gaaatctttt tccattacag tgagttctct ggtgatgttg atagcctgga actgggggac   2100

atggtcgagt atagcttgtc caaaggcaaa ggcaacaaag tcagtgcaga aaaagtgaac   2160

aaaacacact cagtgaatgg cattactgag gaagctgatc ccaccattta ctctggcaaa   2220

gtaattcgcc ccctgaggag tgttgatcca acacagactg agtaccaagg aatgattgag   2280

attgtggagg agggcgatat gaaaggtgag gtctatccat ttggcatcgt tgggatggcc   2340

aacaaagggg attgcctgca gaaaggggag agcgtcaagt tccaattgtg tgtcctgggc   2400

caaaatgcac aaactatggc ttacaacatc acacccctgc gcagggccac agtggaatgt   2460

gtgaaagatc agtttggctt cattaactat gaagtaggag atagcaagaa gctctttttc   2520

catgtgaaag aagttcagga tggcattgag ctacaggcag gagatgaggt ggagttctca   2580

gtgattctta atcagcgcac tggcaagtgc agcgcctgta atgtttggcg agtctgtgag   2640

ggccccaagg ctgttgcagc tcctcgacct gatcggttgg tcaatcgctt gaagaatatc   2700

actctggatg atgccagtgc tcctcgccta atggttcttc gtcagccaag gggaccagat   2760

aactcaatgg ggtttggtgc agaaagaaag atccgtcaag ctggtgtcat tgactaacca   2820

catccacaaa gcacaccatt aatccactat gatcaagttg gggggaatct ggtgaagggt   2880

tctgaatatc tccctcttca tccctcccga aatctggaat acttattcta ttgagctatt   2940

acaccagttt taacaccttc ctcgtgttat gtttaaaaaa ataaataaat ttaagaaaac   3000

cattttaaat aatgcacagt tgcagcctgg aaaaacttaa ggtggcgcct tatagtatca   3060

attttaggag ctttatttgg tgcatttaac gcaactggta attgcagaat ccactttgcc   3120

tgtgtaagtg aaaaatatag actgttatct tgttggccct atgaaattct gcacttttca   3180

ttatatactc taccttcatt aattacttct ggcaagatgt tctgccttag cactcagttg   3240

cattcttttc ctttttcttc ctgttcatta tgctttaatt ctgaggacca tatgagggta   3300

gaatatatta tcttttaaaa attacaaaaa tttgtatagg caaaccattt cttaaagttg   3360

atggccaaat tttaaaatgt tatttttcat atcatttata atcttgtcac aatccactta   3420

aagaagtttg gttatatttc agtgaaaatt ttcttccaga gtaggttttt tttcgtgggt   3480

tggggggtaa ctttactaca attagtaagt atggtgcaga atttcatgca aatgaggagt   3540

gccagcagtg tgataattta aacatattta aacaaaaaca aaaaaaatga atgcacaaac   3600

ttgctgctgc ttagatcact gcagcttcta ggacccggtt tcttttactg atttaaaaac   3660

aaaacaaaaa aaaataaaaa agttgtgcct gaaatgaatc ttgttttttt ttataagtag   3720

ccgcctggtt actgtgtcct gtaaaataca gacacttgac ccttggtgta gcttctgttc   3780

aactttatat cacgggaatg gatgggtctg atttcttggc cctcttcttg aattggccat   3840

atacagggtc cctggccagt ggactgaagg ctttgtctaa gatgacaagg gtcagctcag   3900

gggatgtggg ggagggcggt tttatcttcc cccttgtcgt ttgaggtttt gatctctggg   3960

taaagaggcc gtttatcttt gtaaacacga aacatttttg ctttctccag ttttctgtta   4020

atggcgaaag aatggaagcg aataaagttt tactgatttt tgagacacta gcaaaaaaaa   4080

aaaaaaaaaa                                                          4090


<210>  661
<211>  10759
<212>  DNA
<213>  Human

<400>  661
gcggggggag gggaggggag gggagggggc gcggggccgc ggcagcggag ctcgcatcct     60

cggcggggcg gctgtgcagg aggcggcgcc cgggcgtcag cggacggacc gatcgacggc    120

caagggcgcg cggaccgacg gcggctgccc ggaggggatc gcgggcctcg gagacagcga    180

ctgcggacga tgcgcggccc caggccccgc gcgagcgggc gctgcccggg gggctgaccg    240

cggccggacg gcgccccagc accgggcgag ggagcccgcg tcgcgcggag gtcagggagc    300

ctgagctgga gccagggccc cagtgggacc tgacccaaag tctgaggtca agctgggccc    360

agagcctggc ctggagctgg agcccaaggc acagctggac tacccttgtc atgcagaagg    420

agctgggcat tgtgccttcc tgccctggca tgaagagccc caggccccac ctcctgctac    480

cattgctgct gctgctgctg ctgctgctgg gggctggggt gccaggtgcc tggggtcagg    540

ctgggagcct ggacttgcag attgatgagg agcagccagc gggtacactg attggcgaca    600

tcagtgcggg gcttccggca ggcacggcag ctcctctcat gtacttcatc tctgcccaag    660

agggcagcgg cgtgggcaca gacctggcca ttgacgaaca cagtggggtc gtccgtacag    720

cccgtgtctt ggaccgtgag cagcgggacc gctaccgctt cactgcagtc actcctgatg    780

gtgccaccgt agaagttaca gtgcgagtgg ctgacatcaa cgaccatgct ccagccttcc    840

cacaggctcg ggctgccctg caggtacctg agcatacagc ttttggcacc cgctacccac    900

tggagcctgc tcgtgatgca gatgctgggc gtctgggaac ccagggctat gcgctatctg    960

gtgatggggc tggagagacc ttccggctgg agacacgccc cggtccagat gggactccag   1020

tacctgagct ggtagttact ggggaactgg accgagagaa ccgctcacac tatatgctac   1080

agctggaggc ctatgatggt ggttcacccc cccggagggc ccaggccctg ctggacgtga   1140

cactgctgga catcaatgac catgccccgg ctttcaatca gagccgctac catgctgtgg   1200

tgtctgagag cctggcccct ggcagtcctg tcttgcaggt gttcgcatct gatgccgatg   1260

ctggtgtcaa tggggctgtg acttacgaga tcaaccggag gcagagcgag ggtgatggac   1320

ccttctccat cgacgcacac acggggctgc tgcagttaga gcggccactg gactttgagc   1380

agcggcgggt ccatgaactg gtggtgcaag cacgagatgg tggggctcac cctgagctgg   1440

gctcggcctt tgtgactgtg catgtgcgag atgccaatga caatcagccc tccatgactg   1500

tcatctttct cagtgcagat ggctcccccc aagtgtctga ggccgcccca cctggacagc   1560

tcgttgctcg catctctgtg tcagacccag atgatggtga ctttgcccat gtcaatgtgt   1620

ccctggaagg tggagagggc cactttgccc taagcaccca agacagcgtc atctatctgg   1680

tgtgtgtggc tcggcggctg gatcgagagg agagggatgc ctataacttg agggttacag   1740

ccacagactc aggctcacct ccactgcggg ctgaggctgc ctttgtgctg cacgtcactg   1800

atgtcaacga caatgcacct gcctttgacc gccagctcta ccgacctgag cccctgcctg   1860

aggttgcgct gcctggcagc tttgtagtgc gggtgactgc tcgggatcct gaccaaggca   1920

ccaatggtca ggtcacttat agcctagccc ctggcgccca cacccactgg ttctccattg   1980

accccacctc aggcattatc actacggctg cctcactgga ctatgagttg gaacctcagc   2040

cacagctgat tgtggtggcc acagatggtg gcctgccccc tctagcctcc tctgccacag   2100

ttagcgtggc cctgcaagat gtgaatgata atgagcccca attccagagg actttctaca   2160

atgcctcact gcctgagggc acccagcctg gaacttgctt cctgcaggtg acagccacag   2220

acgcggatag tggcccattt ggcctcctct cctattcctt gggtgctgga cttgggtcct   2280

ccggatctcc cccattccgc attgatgccc atagcggtga tgtgtgcaca acccggaccc   2340

tggaccgtga ccaggggccc tcaagctttg acttcacagt gacagctgtg gatgggggag   2400

gcctcaagtc catggtatat gtgaaggtgt ttctgtcaga cgagaatgac aaccctcctc   2460

agttttatcc acgggagtat gctgccagta taagtgccca gagtccacca ggcacagctg   2520

tgctgaggtt gcgtgcccat gaccctgacc agggatccca tgggcgactc tcctaccata   2580

tcctggctgg caacagcccc ccacttttta ccttggatga gcaatcaggg ctgttgacag   2640

tagcctggcc cttggccaga cgggccaatt ctgtggtgca gctggagatc ggggctgagg   2700

acggaggtgg cctacaggca gaacccagtg cccgagtgga catcagcatt gtgcctggaa   2760

cccccacacc acccatattt gagcaactac agtatgtttt ttctgtgcca gaggatgtgg   2820

caccaggcac cagtgtgggc atagtccagg cacacaaccc accaggtcgc ttggcacctg   2880

tgaccctttc cctatcaggt ggggatcccc gaggactctt ctccctagat gcggtatcag   2940

gactgttgca aacacttcgc cctctggacc gggagctact gggaccagtg ttggagctgg   3000

aggtgcgagc aggcagtgga gtgcccccag ctttcgctgt agctcgggtg cgtgtgctgc   3060

tggatgatgt gaatgacaac tcccctgcct ttcctgcacc tgaagacacg gtattgctac   3120

caccaaacac tgccccaggg actcccatct atacactgcg ggctcttgac cccgactcag   3180

gtgttaacag tcgagtcacc tttaccctgc ttgctggggg tggtggagcc ttcaccgtgg   3240

accccaccac aggccatgta cggcttatga ggcctctggg gccctcagga gggccagccc   3300

atgagctgga gctggaggcc cgggatgggg gctccccacc acgcaccagc cactttcgac   3360

tacgggtggt ggtacaggat gtgggaaccc gtgggctggc tccccgattc aacagcccta   3420

cctaccgtgt ggacctgccc tcaggcacca ctgctggaac tcaggtcctg caagtgcagg   3480

cccaagcacc agatgggggc cctatcacct atcaccttgc agcagaggga gcaagtagcc   3540

cctttggcct ggagccacag agtgggtggc tatgggtgcg ggcagcacta gaccgtgagg   3600

cccaggaatt gtacatactg aaggtaatgg cagtgtctgg gtccaaagct gagttggggc   3660

agcagacagg cacagccacc gtgagggtca gcatcctcaa ccagaatgaa cacagtcccc   3720

gcttgtctga ggatcccacc ttcctggctg tggctgagaa ccagccccca gggaccagcg   3780

tgggccgagt ctttgccact gaccgagact caggacccaa tggacgtctg acctacagcc   3840

tgcaacagct gtctgaagac agcaaggcct tccgcatcca cccccagact ggagaagtga   3900

ccacactcca aaccctggac cgtgagcagc agagcagcta tcagctcctg gtgcaggtgc   3960

aggatggagg gagcccaccc cgcagcacca caggcactgt gcatgttgca gtgcttgacc   4020

tcaacgacaa cagccccacg ttcctgcagg cttcaggagc tgctggtggg ggcctcccta   4080

tacaggtacc agaccgcgtg cctccaggaa cactggtgac gactctgcag gcgaaggatc   4140

cagatgaggg ggagaatggg accatcttgt acacgctaac tggtcctggc tcagagcttt   4200

tctctctgca ccctcactca ggggagctgc tcactgcagc tcccctgatc cgagcagagc   4260

ggccccacta tgtgctgaca ctgagtgctc atgaccaagg cagccctcct cgaagtgcca   4320

gcctccagct gctggtgcag gtgcttccct cagctcgctt ggccgagccg cccccagatc   4380

tcgcagagcg ggacccagcg gcaccagtgc ctgtcgtgct gacggtgaca gcagctgagg   4440

gactgcggcc cggctctctg ttgggctcgg tggcagcgcc agagcccgcg ggtgtgggtg   4500

cactcaccta cacactggtg ggcggtgccg atcccgaggg caccttcgcg ctggatgcgg   4560

cctcagggcg cttgtacctg gcgcggcccc tggacttcga agctggcccg ccgtggcgcg   4620

cgctcacggt acgcgctgag gggccgggag gcgcgggcgc gcggctgctg cgagtgcagg   4680

tgcaagtgca ggacgagaat gagcatgcgc ccgcctttgc gcgcgacccg ctggcgctgg   4740

cgctgccaga gaacccggag cccggcgcag cgctgtacac tttccgcgcg tcggacgccg   4800

acggccccgg ccccaatagc gacgtgcgct accgcctgct gcgccaggag ccgcccgtgc   4860

cggcgcttcg cctggacgcg cgcaccgggg cgctcagcgc tccgcgcggc ctggaccgag   4920

agaccactcc cgcgctgctg ctgctggtgg aagccaccga ccggcccgcc aacgccagcc   4980

gccgtcgtgc agcgcgcgtt tcagcgcgcg tcttcgtcac ggatgagaat gacaacgcgc   5040

ctgtcttcgc ctcgccgtca cgcgtgcgcc tcccagagga ccagccgcct gggcccgcgg   5100

ccctgcacgt ggtagcccgg gacccggatc tgggcgaggc tgcacgcgtg tcctatcggc   5160

tggcatctgg cggggacggc cacttccggc tgcactcaag cactggagcg ctgtccgtgg   5220

tgcggccgtt ggaccgcgaa caacgagctg agcacgtact gacagtggtg gcctcagacc   5280

acggctcccc gccgcgctcg gccacgcagg tcctgaccgt cagtgtcgct gacgtcaacg   5340

acgaggcgcc tactttccag cagcaggagt acagcgtcct cttgcgtgag aacaaccctc   5400

ctggcacatc tctgctcacc ctgcgagcaa ccgaccccga cgtgggggcc aacgggcaag   5460

tgacttatgg aggcgtctct agcgaaagct tttctctgga tcctgacact ggtgttctca   5520

cgactcttcg ggccctggat cgagaggaac aggaggagat caacctgaca gtgtatgccc   5580

aggacagggg ctcacctcct cagttaacgc atgtcactgt tcgagtggct gtggaggatg   5640

agaatgacca tgcaccaacc tttgggagtg cccatctctc tctggaggtg cctgagggcc   5700

aggaccccca gacccttacc atgcttcggg cctctgatcc agatgtggga gccaatgggc   5760

agttgcagta ccgcatccta gatggggacc catcaggagc ctttgtccta gaccttgctt   5820

ctggagagtt tggcaccatg cggccactag acagagaagt ggagccagct ttccagctga   5880

ggatagaggc ccgggatgga ggccagccag ctctcagtgc cacgctgctt ttgacagtga   5940

cagtgctgga tgccaatgac catgctccag cctttcctgt gcctgcctac tcggtggagg   6000

tgccggagga tgtgcctgca gggaccctgc tgctgcagct acaggctcat gaccctgatg   6060

ctggagctaa tggccatgtg acctactacc tgggcgccgg tacagcagga gccttcctgc   6120

tggagcccag ctctggagaa ctgcgcacag ctgcagcctt ggacagagaa cagtgtccca   6180

gctacacctt ttctgtgagt gcagtggatg gtgcagctgc tgggccccta agcaccacag   6240

tgtctgtcac catcacggtg cgcgatgtca atgaccatgc acccaccttc cccaccagtc   6300

ctctgcgcct acgtctgccc cgcccaggcc ccagcttcag taccccaacc ctggctctgg   6360

ccacactgag agctgaagat cgtgatgctg gtgccaatgc ttccattctg taccggctgg   6420

caggcacacc acctcctggc actactgtgg actcttacac tggtgaaatc cgcgtggccc   6480

gctctcctgt agctctaggc ccccgagatc gtgtcctctt cattgtggcc actgatcttg   6540

gccgtccagc tcgctctgcc actggtgtga tcattgttgg actgcagggg gaagctgagc   6600

gtggaccccg ctttccccgg gctagcagtg aggctacgat tcgtgagaat gcgcccccag   6660

ggactcctat tgtctccccc agggccgtcc atgcaggagg cacaaatgga cccatcacct   6720

acagcattct cagtgggaat gagaaaggga cattctccat ccagcctagt acaggtgcca   6780

tcacagttcg ctcagcagag gggctagact tcgaggtgag tccacggctg cgactggtgc   6840

tgcaggcaga gagtggagga gcctttgcct tcactgtgct gaccctgacc ctgcaagatg   6900

ccaacgacaa tgctccccgt ttcctgcggc cccattatgt ggccttcctt cctgagtccc   6960

ggcccttgga ggggcccctg ctgcaggtgg aggcggatga cctggatcaa ggctctggag   7020

gacagatttc ctacagtctg gctgcatccc agccggcacg tggattgttc cacgtagacc   7080

caaccacagg cactatcact accacagcca tcctggaccg tgagatctgg gctgaaacac   7140

ggttggtgct gatggccaca gacagaggga gcccagccct ggtgggctca gctaccttga   7200

cggtgatggt catcgacacc aatgacaatc gccccaccat cccccaaccc tgggagctcc   7260

gagtgtcaga agatgcgtta ttgggctcag agattgcaca ggtaacaggg aatgatgtgg   7320

actcaggacc cgtgctgtgg tatgtgctaa gcccatctgg gccccaggat cccttcagtg   7380

ttggccgcta tggaggccgt gtctccctca cggggcccct ggactttgag cagtgtgacc   7440

gctaccagct gcagctgctg gcacatgatg ggcctcatga gggccgtgcc aacctcacag   7500

tgcttgtgga ggatgtcaat gacaatgcac ctgccttctc acagagcctc taccaggtaa   7560

tgctgcttga gcacacaccc ccaggcagtg ccattctctc cgtctctgcc actgatcggg   7620

actcaggtgc caacggtcac atttcctacc acctggcttc ccctgccgat ggcttcagtg   7680

ttgaccccaa caatgggacc ctgttcacaa tagtgggaac agtggccttg ggccatgacg   7740

ggtcaggagc agtggatgtg gtgctggaag cacgagacca cggggctcca ggccgggcag   7800

cacgagccac agtgcacgtg cagctgcagg accagaacga ccacgccccg agcttcacat   7860

tgtcacacta ccgtgtggct gtgactgaag acctgccccc tggctccact ctgctcaccc   7920

tggaggctac agatgctgat ggaagccgca gccatgccgc tgtggactac agcatcatca   7980

gtggcaactg gggccgagtc ttccagctgg aacccaggct ggctgaggct ggggagagtg   8040

ctggaccagg cccccgggca ctgggctgcc tggtgttgct tgaacctcta gactttgaaa   8100

gcctgacaca gtacaatcta acagtggctg cagctgaccg tgggcagcca ccccaaagct   8160

cagtcgtgcc agtcactgtc actgtactag atgtcaatga caacccacct gtctttaccc   8220

gagcatccta ccgtgtgaca gtacctgagg acacacctgt tggagctgag ctgctgcatg   8280

tagaggcctc tgacgctgac cctggccctc atggcctcgt gcgtttcact gtcagctcag   8340

gcgacccatc agggctcttt gagctggatg agagctcagg caccttgcga ctggcccatg   8400

ccctggactg tgagacccag gctcgacatc agcttgtagt acaggctgct gaccctgctg   8460

gtgcacactt tgctttggca ccagtgacaa ttgaggtcca ggatgtgaat gatcatggcc   8520

cagccttccc actgaactta ctcagcacca gcgtggccga gaatcagcct ccaggcactc   8580

tcgtgaccac tctgcatgca atcgacgggg atgctggggc ttttgggagg ctccgttaca   8640

gcctgttgga ggctgggcca ggacctgagg gccgtgaggc atttgcactg aacagctcaa   8700

caggggagtt gcgtgcgcga gtgccctttg actatgagca cacagaaagc ttccggctgc   8760

tggtgggtgc tgctgatgct gggaatctct cagcctctgt cactgtgtcg gtgctagtga   8820

ctggagagga tgagtatgac cctgtatttc tggcaccagc tttccacttc caagtgcccg   8880

aaggtgcccg gcgtggccac agcttgggtc acgtgcaggc cacagatgag gatgggggtg   8940

ccgatggcct ggttctgtat tcccttgcca cctcttcccc ctattttggt attaaccaga   9000

ctacaggagc cctgtacctg cgggtggaca gtcgggcacc aggcagcgga acagccacct   9060

ctgggggtgg gggccggacc cggcgggaag caccacggga gctgaggctg gaggtgatag   9120

cacgggggcc tctgcctggt tcccggagtg ccacagtgcc tgtgaccgtg gatatcaccc   9180

acaccgcact gggcctggca cctgacctca acctgctatt agtaggggcc gtggcagcct   9240

ccttgggagt tgtggtggtg cttgcactgg cagccctggt cctaggactt gttcgggccc   9300

gtagccgcaa ggctgaggca gcccctggcc caatgtcaca ggcagcaccc ctagccagtg   9360

actcactgca gaaactgggc cgggagccac ctagtccacc accctctgag cacctctatc   9420

accagactct tcccagctat ggtgggccag gagctggagg accctacccc cgtggtggct   9480

ccttggaccc ttcacattca agtggccgag gatcagcaga ggctgcagag gatgatgaga   9540

tccgcatgat caatgagttc ccccgtgtgg ccagtgtggc ctcctctctg gctgcccgtg   9600

gccctgactc aggcatccag caggatgcag atggtctgag tgacacatcc tgcgaaccac   9660

ctgcccctga cacctggtat aagggccgaa aggcagggct gctgctgcca ggtgcaggag   9720

ccactctcta cagagaggag gggcccccag ccactgccac agccttcctg gggggctgtg   9780

gcctgagccc tgcacccact ggggactatg gcttcccagc agatggcaag ccatgtgtgg   9840

caggtgcgct gacagccatt gtggccggcg aggaggagct ccgtggcagc tataactggg   9900

actacctgct gagctggtgc cctcagttcc aaccactggc cagtgtcttc acagagatcg   9960

ctcggctcaa ggatgaagct cggccatgtc ccccagctcc ccgtatcgac ccaccacccc  10020

tcatcactgc cgtggcccac ccaggagcca agtctgtgcc ccccaagcca gcaaacacag  10080

ctgcagcccg ggccatcttc ccaccagctt ctcaccgctc ccccatcagc catgaaggct  10140

ccctgtcctc agctgccatg tcccccagct tctcaccctc tctgtctcct ctggctgctc  10200

gctcacccgt tgtctcacca tttggggtgg cccagggtcc ctcagcctca gcactcagcg  10260

cagagtctgg cctggagcca cctgatgaca cggagctgca catctagctg tggcccaggc  10320

tgggccccga cctgggatgc gcacagtgtc cccaacgcag gccccactct gagcctgccc  10380

tgggcagcct cggactatga ctggctacgg ggaggccacc accaggcccc agctctccac  10440

cctgaactcc ccagccccct cagagtacta ggaccacaga agccctgttg ctcactgacc  10500

tgtgaccagg tccaatgtgg ggagaaatat gaaggaggta gcagccctgg gttctcctca  10560

gtgagggatc cctgccctgc accagcaccc tgagatggag ctgagacttt atttattggg  10620

ggtaggggga tggaggaggt ccctccaaca tgtttggacc cagctccttt gggttccact  10680

gacacccctg cccctgcccc tgcccagaac caagtgccat ttctcactct ggagccttaa  10740

taaactgcaa tttgtatcc                                               10759


<210>  662
<211>  5688
<212>  DNA
<213>  Human

<400>  662
ggtgggggta gcggcggcgc ccgcggcccg gagcgggggt tgggggagta gagaaagcgg     60

ggcgcgcgga ggaacgctgg gtccccggcg ccgcgggagc tgggaggacc gagccggccg    120

agcgagcagc gcggcagcac agtccccgcg tggcgcagcg cggcggggac gcggggaccg    180

cccggatctc cttccactgc gccccgcgct ctgcggtcct cggccgcctc ttcttccttc    240

actcactgcc cgggcgggag cggcgcccaa gtcgggtgcg ccatgtctgg ggccgggtag    300

ccccgccgcc cgccggcccg ccagctcgcc ctccgagcca cccgccagcg ggccggccgg    360

ccgggaagcg cgggacagat gcagtgagtg aggggggggc catggcggag gagcggcccc    420

cccggctggt ggattacttc gtggtagctg ggcttgcagg gaacggagca cccatccctg    480

aggaaacgtg ggttcctgaa cccagtgggc ccctgcgccc tccccggcca gctgagccca    540

tcacagatgt ggcagtcatc gctagggcac tgggcgagga agtgccccag ggctacacat    600

gcatccaggc ttctgctggg ggccacccct tggaactcag tgctggactt ctgggtggaa    660

ctcaacccgt catctgctac cgcaggggcc gtgacaagcc ccccctcgtt gagctggggg    720

tgttgtatga ggggaaggaa cgtcccaagc ctggcttcca agtgcttgac acgacaccct    780

acagccactc agcaaacctg gcccctccag gccccgggca cccccgcacc tacctcactt    840

accggcgggc agcagagggg gcagggctgc atgccctggg catcactgac ctctgcctgg    900

tgctgcccag taagggcgag ggcactcctc atacttactg ccggctgccc cgcaacctca    960

accctggcat gtggggccca gcagtgtacc tgtgctataa ggtgggcctg gcgaaggcca   1020

acacgctggt gtacgaggca gagctgctgg gccgctaccc ggaggaggac aatgaggcgt   1080

tcccgctgcc cgagtcagtg cccgtcttct gcctgcccat gggggccact atcgagtgct   1140

ggcctgccca gaccaagtac cccgtgcccg tcttctccac ctttgtgctc acgggtgcag   1200

ctggtgataa ggtgtatggt gccgccctgc agttctacga ggcgttccca agggccaggc   1260

tatcagagcg acaggcacgg gcactgggcc tgctgagcgc cgtggagcgg ggtcgggcac   1320

tggggggcag agctgtgcgc agccggcgtg ccatcgctgt gctgtcccgc tggcctgcct   1380

tccctgcctt ccgcgccttc ctcaccttcc tttaccgcta ctccgtctca ggcccccacc   1440

gcctaccctt ggaagcgcac atctcccact tcattcacaa cgttcccttc ccttccccac   1500

agagaccccg catcctagtg cagatgtctc cctatgacaa cttgctcctc tgtcagcctg   1560

tatcctcacc cctgcccctc agtggtgcca gcttcctgca gctgctgcag agcctgggcc   1620

ctgagctggc tatcacactg ctgctggctg tgctcacaga gcacaagctg ctagtccact   1680

cgctgcggcc agacctgctc accagcgtct gtgaggccct cgtctcgatg atcttcccac   1740

tgcactggca gtgcccctac attcctctgt gcccgctggt gctggcagat gtgctgagtg   1800

ccccagtgcc cttcattgtg ggtatccact ccagctactt tgatctgcat gacccgcctg   1860

ctgatgtcat ctgtgtagac cttgatacca acacgctctt ccagactgag gaaaagaagc   1920

tcctctcccc tcggaccctg ccccgcagac cctacaaggt tctgctggcc acactgacaa   1980

acctgtacca gcagctggac cagacataca ctggacctga ggaggaagca tccctggagt   2040

tcctactgac agactacgag gcagtgtgtg gccgcagggc ccggctggag cgcgaagtcc   2100

aaggagcctt cctccgcttc atggcctgtc tgctcaaggg ctaccgggtc ttcctgcgcc   2160

cactcaccca ggccccctcc gagggagctc gtgatgttga caaccttttc ttcctgcagg   2220

gcttcctcaa atcccgggaa cgctccagcc acaaacttta ctctcagctg ctgcacacac   2280

agatgttctc acagttcatt gaggagtgct cttttggctc tgctcgccat gctgcccttg   2340

aattctttga ctcttgtgtt gaaaaggtcc acccagagca ggagaagcct gagccgacac   2400

ccttagtgga gctagaggag ctgtcaggaa gtgagctcac tgtctttatc acacctcccg   2460

aggagcctgc cttaccagag ggcagtgaat ccactcccca gtactgctat gatggattcc   2520

cagagctacg ggctgagttg tttgagtctc ttcaagagca acctggggcc ctgcctgtgc   2580

caggcccttc ccgtagcgcc cccagcagtc ctgctcctcg ccgtaccaaa caggagatga   2640

aagttgcaca gcggatggca cagaagtcag cagctgtgcc tgagctgtgg gcccggtgcc   2700

tgctggggca ctgctatggg ctgtggttcc tgtgtctgcc tgcctatgtg cggtcggcac   2760

cctcccgagt gcaggcactg cacacagcct accatgtgct gcgccagatg gagagcggca   2820

aggtggtgct ccctgatgag gtgtgttacc gggtactgat gcagctctgc tcacactatg   2880

ggcagcctgt gctgtctgtg cgggtcatgc tggagatgcg tcaggcaggc attgtgccca   2940

acaccatcac ctatggctac tacaataagg ctgtgttgga aagcaagtgg ccgtctggca   3000

caccaggtgg gcgtctgcgc tgggccaagc tccggaatgt tgtcctgggg gctgctcagt   3060

tccgccagcc cttgagagaa cggcaacagc agcagcagca gcaacagcag cagcagcagc   3120

agcagcagca ggagcaggtg tcagcacatc aagaggcagg cagctcccag gcagagccct   3180

atttggagcg cccttcccct actcgccctc ttcagcgcca gactacttgg gctgggcgaa   3240

gtctgagaga cccagcctca ccccctggac gcctggtgaa gagtggtagc ctgggcagtg   3300

cccgaggggc acagcccact gtggaggccg gtgtggccca catgatagag gccttggggg   3360

tcctggaacc ccggggatca cctgtgccct ggcacgatgg aagtctctca gacctgagcc   3420

tgacagggga ggagccgctc cctggaggca gcccaggggg ctcaggctca gccctgagtg   3480

cccagtccac tgaggccctg gaagggctaa gtgggcgggg acccaaggct ggtgggcgac   3540

aggatgaggc aggcaccccc cgacgagggc tgggtgcccg cctccaacag ctgctcactc   3600

cttcccgcca ctcccctgcc tcccgcattc ccccacctga gctgcctcct gacctgccac   3660

ccccagcccg ccgcagcccc atggacagtc ttctgcaccc ccgggagcgc cctggatcca   3720

ctgcctccga gagctcagcc tctctgggca gtgagtggga cctctcagaa tcttctctca   3780

gcaacctgag tcttcgccgt tcctcagagc gcctcagtga cacccctgga tccttccagt   3840

caccttccct ggaaattctg ctgtccagct gctccctgtg ccgtgcctgt gattcgctgg   3900

tgtatgatga ggaaatcatg gctggctggg cacctgatga ctctaacctc aacacaacct   3960

gccccttctg cgcctgcccc tttgtgcccc tgctcagtgt ccagaccctt gattcccggc   4020

ccagtgtccc cagccccaaa tctgctggtg ccagtggcag caaagatgct cctgtccctg   4080

gtggtcctgg ccctgtgctc agtgaccgaa ggctctgcct tgctctggat gagccccagc   4140

tctgcaacgg gcacatgggg ggagcctccc ggcgggttga gagtggggca tgggcatacc   4200

tgagccccct ggtgctgcgt aaggagctgg agtcgctggt agagaacgag ggcagtgagg   4260

tgctggcgtt gcctgaactg ccctctgccc accccatcat cttctggaac cttttgtggt   4320

atttccaacg gctacgcctg cccagtattc taccaggcct ggtgctggcc tcctgtgatg   4380

ggccttcgca ctcccaggcc ccatctcctt ggctaacccc tgatccagcc tctgttcagg   4440

tacggctgct gtgggatgta ctgacccctg accccaatag ctgcccacct ctctatgtgc   4500

tctggagggt ccacagccag atcccccagc gggtggtatg gccaggccct gtacctgcat   4560

cccttagttt ggcactgttg gagtcagtgc tgcgccatgt tggactcaat gaagtgcaca   4620

aggctgtggg gctcctgctg gaaactctag ggcccccacc cactggcctg cacctgcaga   4680

ggggaatcta ccgtgagata ttattcctga caatggctgc tctgggcaag gaccacgtgg   4740

acatagtggc cttcgataag aagtacaagt ctgcctttaa caagctggcc agcagcatgg   4800

gcaaggagga gctgaggcac cggcgggcgc agatgcccac tcccaaggcc attgactgcc   4860

gaaaatgttt tggagcacct ccagaatgct agagacctta agcttccctc tccagcctag   4920

ggtggggaag tgaggaagaa gggattctag agttaaactg cttccctgtt gccttcatgg   4980

agttgggaac aggctgggaa ggatgcccag tcaaaggctc caagcgagga caacaggaag   5040

agggatccac tgttaccaaa agtcctgatt cccccatcac caacctaccc agtttgttcg   5100

tgctgatgtt gggggagatc tggggggagt tggtacagct ctgttcttcc cttgtcctat   5160

accgggaact cccctccagg gtacccacag atctgcattg ccctggtcat tttagaagtt   5220

tttgttttaa aaaacaactg gaaagatgca gagctactga gcctttgccc tgaatgggag   5280

gtagggatgt cattctccac caataatggt ccctcttccc tgacgttgct gaaggagccc   5340

aaggctctcc atgcctttct acctaagtgt ttgtatttta ttttaaatta tttattctgg   5400

agccacagcc cccttgctta tgaggttctt atggagagtg agaaagggaa gggaaatagg   5460

gcaccatggt ccggtggttt gtagttcctt caaagtcagg cactgggagc tagaggagtc   5520

tcaagctccc cttaggaaga actggtgccc cctccagtcc taatttttct tgcctgcccc   5580

gccttgggga atgcctcacc cacccaggtc ctgacctgtg caataaggat tgttccctgc   5640

gaagttttgt tggatgtaaa tatagtaaaa gctgcttctg tctttttc                5688


<210>  663
<211>  2857
<212>  DNA
<213>  Human

<400>  663
ccacttccgg ttgttgtccg gccctatatc cggtgtccgc ccgccctcgg ctcctccgcc     60

gtgatgctgt cccgatcccg ctgtgtgtct cgggcgttca gccgctcgct ctccgccttc    120

cagaagggga actgccctct agggagacgt tccctgcctg gggtctcctt atgccaggga    180

ccaggttacc ctaacagcag gaaggttgtc attaacaaca gtgtcttcag tgttcgcttt    240

ttcagaacta cagctgtatg caaggatgac ttggttacag tcaaaacccc agcgtttgca    300

gaatctgtca cagagggaga tgtcaggtgg gagaaagctg ttggagacac agttgcagaa    360

gatgaagtgg tttgtgagat tgaaactgac aagacatctg tgcaggttcc atcaccagca    420

aatggcgtga ttgaagctct tttggtacct gatgggggaa aagtcgaagg aggcactcca    480

cttttcacac tcaggaaaac tggtgctgct cctgctaagg ccaagccggc tgaagctcct    540

gctgctgcag ccccaaaagc agaacctaca gcagcggcag ttcctccccc tgcagcaccc    600

atacccactc agatgccacc ggtgccctcg ccctcacagc ctccttctgg caaacctgtg    660

tctgcagtaa aacccactgt tgccccacca ctagctgagc caggagctgg caaaggtctg    720

cgttcagaac atcgggagaa aatgaacagg atgcggcagc gcattgctca gcgtctgaag    780

gaggcccaga atacatgtgc aatgctgaca acttttaatg agattgacat gagtaacatc    840

caggagatga gggctcggca caaagaggct tttttgaaga aacataacct caaactaggc    900

ttcatgtcgg catttgtgaa ggcctcagcc tttgccttgc aggaacagcc tgttgtaaat    960

gcagtgattg acgacacaac caaagaggtg gtgtataggg attatattga catcagtgtt   1020

gcagtggcca ccccacgggg tctggtggtt ccagtcatca ggaatgtgga agctatgaat   1080

tttgcagata ttgaacggac catcactgaa ctgggagaga aggcccgaaa gaatgaactt   1140

gccattgaag atatggatgg cggtaccttc accattagca atggaggcgt ttttggctcg   1200

ctctttggaa cacccattat caacccccct cagtctgcca tcctggggat gcatggcatc   1260

tttgacaggc cagtggctat aggaggcaag gtagaggtgc ggcccatgat gtacgtggca   1320

ctgacctatg atcaccggct gattgatggc agagaggctg tgactttcct ccgcaaaatc   1380

aaggcagcgg tagaggatcc cagagtcctc ctcctggatc tttaggagga acccacacac   1440

cctacaagtt gatcatgcag gaactgaaaa ccagtcttct ccctgtcccc tcatgggtcc   1500

cgggttagcc tggtgacagg cagacacatg ctgttggcct caagcaagga agcagagcac   1560

tgtgtaacca gcagtcacag gtcttttctt ggcgttcctg ccaggctctc cctctctgca   1620

cctgtctcat agcctcgaat atcttaattc cttaggctta agagagagag ccttaatgga   1680

tgctcattca tattcctgcc tttcttccat cagctctctg caaagatgat tttgcttttc   1740

cctagtgctg gtatactata gagaaacccc tggggaccat gtgattaagt tcctatcttt   1800

tgaaagtttg ttctgcagag acttctagga ggatgctgtg cctcccaagc tcagagcagc   1860

ctctgtcctg gctgtgcaca ttctcccttg attccacttg tgtggaggga ttgaacacag   1920

gcaaagaggt gctgctttgc ttcttcaatg gcaccttcat tctccgttgt cattgacttc   1980

aagatgcctc ttctacctct tccaggaagc acaggccagg ggatctgggt gtgtgagtgg   2040

gaggagaggg cagaggtccc ctgaggtcat gcattgtaat catcatagaa ggagagccca   2100

ggcctgccct cacgctctcc atcataggct gacaccaaga agactcgtct tggcacaatc   2160

tcacacagct ggggctgtag caaccctttc caaccccttt gctggttgct gggcctcatt   2220

ctagcacctt gttcttagag cagattctag cacatcatgg cagtgggacc aagcgtggtc   2280

ccgaggaagg gccagagcct ggtagagact agggaaggga ggtctcctct agactgactc   2340

acattgcctt gagcttttca gttaagttgc tgtaagcacc tgggctgagg aggcagtttt   2400

tgttccttcc tgcgttatag cggggccttg tctcttcctc tgcaggacac agatctggag   2460

gacgtggact ggggtaggaa accaccctga gggtgttagt acctagtggt gaaacggatg   2520

aggtcatttc taaggtgtgt tgcccgtgga tctgggcaca atcattggaa ttccttggag   2580

ccactgggat tcatggcttt gtatccaact gcatccaggc ctgaggctgc tgacgtttga   2640

caccagggcc agtagagagt gcccttttgt atcttaagcc aagaagtgag gcctgggggt   2700

gggggagggg ggaaggggtg ggagccaata ctgagtgcct gcagcatcta ctactctgtc   2760

ttcactattc agaacttgta actaaagtat ttaaagaaac tgattttaaa tgcaaattaa   2820

agggcagata ttctcaaaca ggaaaaaaaa aaaaaaa                            2857


<210>  664
<211>  7455
<212>  DNA
<213>  Human

<400>  664
cccgcctagc atggtgcggc ggccgcgcgc gcggacatgg gggagaagct ggagctgaga     60

ctgaagtcgc ccgtgggggc tgagcccgcc gtctacccgt ggccgctgcc ggtctacgat    120

aaacatcacg atgctgctca tgaaatcatc gagaccatcc gatgggtctg tgaagaaatc    180

ccggatctca agctcgctat ggagaattac gttttaattg actatgacac caaaagcttc    240

gagagcatgc agaggctctg cgacaagtac aaccgtgcca tcgacagcat ccaccagctg    300

tggaagggca ccacgcagcc catgaagctg aacacgcggc cgtccactgg actcctgcgc    360

catatcctgc agcaggtcta caaccactcg gtgaccgacc ccgagaagct caacaactac    420

gagcccttct cccccgaggt gtacggggag acctccttcg acctggtggc ccagatgatt    480

gatgagatca agatgaccga cgacgacctg tttgtggact tggggagcgg tgtgggccag    540

gtcgtgctcc aggttgctgc tgccaccaac tgcaaacatc actatggcgt cgagaaagca    600

gacatcccgg ccaagtatgc ggagaccatg gaccgcgagt tcaggaagtg gatgaaatgg    660

tatggaaaaa agcatgcaga atacacattg gagagaggcg atttcctctc agaagagtgg    720

agggagcgaa tcgccaacac gagtgttata tttgtgaata attttgcctt tggtcctgag    780

gtggatcacc agctgaagga gcggtttgca aacatgaagg aaggtggcag aatcgtgtcc    840

tcgaaaccct ttgcacctct gaacttcaga ataaacagta gaaacttgag tgacatcggc    900

accatcatgc gcgtggtgga gctctcgccc ctgaagggct cggtgtcgtg gacggggaag    960

ccagtctcct actacctgca cactatcgac cgcaccatac ttgaaaacta tttttctagt   1020

ctgaaaaacc caaaactcag ggaggaacag gaggcagccc ggcgccgcca gcagcgcgag   1080

agcaagagca acgcggccac gcccactaag ggcccagagg gcaaggtggc cggccccgcc   1140

gacgccccca tggactctgg tgctgaggaa gagaaggcgg gagcagccac cgtgaagaag   1200

ccgtctccct ccaaagcccg caagaagaag ctaaacaaga aggggaggaa gatggctggc   1260

cgcaagcgcg ggcgccccaa gaagatgaac actgcgaacc ccgagcggaa gcccaagaag   1320

aaccaaactg cactggatgc cctgcacgct cagaccgtgt ctcagacggc ggcctcctca   1380

ccccaggatg cctacagatc ccctcacagc ccgttctacc agctacctcc gagcgtgcag   1440

cggcactccc ccaacccgct gctggtggcg cccaccccgc ccgcgctgca gaagcttcta   1500

gagtccttca agatccagta cctgcagttc ctggcataca caaagacccc ccagtacaag   1560

gccagcctgc aggagctgct gggccaggag aaggagaaga acgcccagct cctgggtgcg   1620

gctcagcagc tcctcagcca ctgccaggcc cagaaggagg agatcaggag gctgtttcag   1680

caaaaattgg atgagctggg tgtgaaggcg ctgacctaca acgacctgat tcaagcgcag   1740

aaggagatct ccgcccataa ccagcagctg cgggagcagt cggagcagct ggagcaggac   1800

aaccgcgcgc tccgcggcca gagcttgcag ctgctcaagg ctcgctgcga ggagctgcag   1860

ctggactggg ccacgctgtc gctggagaag ctgttgaagg agaagcaggc cctgaagagc   1920

cagatctcgg agaagcagag gcactgcctg gagctgcaga tcagcattgt ggagctagag   1980

aagagccagc ggcagcagga gctcctgcag ctcaagtcct gtgtgccgcc tgacgacgcc   2040

ctgtccctgc acctgcgtgg gaagggcgcc ctgggccgcg agctggagcc tgacgccagc   2100

cggctgcacc tggagctgga ctgcaccaag ttctcgctgc ctcacttgag cagcatgagc   2160

ccggagctct ccatgaacgg ccaggctgct ggctatgagc tctgcggtgt gctgagccgg   2220

ccttcgtcga agcagaacac gccccagtac ctggcctcac ccctggacca ggaggtggtg   2280

ccctgtaccc ctagccacgt cggccggccg cgcctggaga agctgtctgg cctagccgca   2340

cccgactaca ctaggctgtc cccggccaag attgtgctga ggcggcacct gagccaggac   2400

cacacggtgc ccggcaggcc ggctgccagt gagctgcatt cgagagctga gcacaccaag   2460

gagaacggcc ttccctacca gagccccagc gtgcctggca gcatgaagct gagccctcag   2520

gacccgcggc ccctgtcccc tggggccttg cagcttgctg gagagaagag cagtgagaag   2580

ggcctgagag agcgcgccta cggcagcagc ggggagctca tcaccagcct gcccatcagc   2640

atcccgctca gcaccgtgca gcccaacaag ctcccggtca gcattcccct ggccagcgtg   2700

gtgctgccca gccgcgccga gagggcgagg agcaccccca gtcccgtgct gcagccccgt   2760

gacccctcgt ccacacttga aaagcagatt ggtgctaatg cccacggtgc tgggagcaga   2820

agccttgccc tggcccccgc aggcttctcc tacgctggct cggtggccat cagcggggcc   2880

ttggcgggca gcccggcctc tctcacacct ggagccgagc cggccacctt ggatgagtcc   2940

tccagctctg ggagcctttt tgccaccgtg gggtcccgca gctccacgcc acagcacccc   3000

ctgctgctgg cacagccccg gaactcgctt cctgcctctc ccgcccacca gctctcctcc   3060

agtccccggc ttggtggggc cgcccagggc ccgttgcccg aggccagcaa gggagacctg   3120

ccctccgatt ccggcttctc agatcctgag agtgaagcca agaggaggat tgtgttcacc   3180

atcaccactg gtgcgggcag tgccaagcag tcgccctcca gcaagcacag ccccctgacc   3240

gccagcgccc gtggggactg tgtgccgagc cacgggcagg acagtcgcag gcgcggccgg   3300

cggaagcgag catctgcggg gacgcccagc ttgagcgcag gcgtgtcccc caagcgccga   3360

gccctgccgt ccgtcgctgg ccttttcaca cagccttcgg ggtctcccct caacctcaac   3420

tccatggtca gtaacatcaa ccagcccctg gagattacag ccatctcgtc cccggagacc   3480

tccctgaaga gctcccctgt gccctaccag gaccacgacc agccccccgt gctcaagaag   3540

gagcggcctc tgagccagac caatggggca cactactccc cactcacctc agacgaggag   3600

ccaggctctg aggacgagcc cagcagtgct cgaattgaga gaaaaattgc aacaatctcc   3660

ttagaaagca aatctccccc gaaaaccttg gaaaatggtg gtggcttggc gggaaggaag   3720

cccgcgcccg ccggcgagcc agtcaatagc agcaagtgga agtccacctt ctcgcccatc   3780

tccgacatcg gcctggccaa gtcggcggac agcccgctgc aggccagctc cgccctcagc   3840

cagaactccc tgttcacgtt ccggcccgcc ctggaggagc cctctgccga tgccaagctg   3900

gccgctcacc ccaggaaagg ctttcccggc tccctgtcgg gggctgacgg actcagcccg   3960

ggcaccaacc ctgccaacgg ctgcaccttc ggcgggggcc tggccgcgga cctgagttta   4020

cacagcttca gtgatggtgc ttctcttccc cacaagggcc ccgaggcggc cggcctgagc   4080

tccccgctga gcttcccctc gcagcgcggc aaggagggct cggacgccaa ccctttcctg   4140

agcaagaggc agctggacgg cctggctggg ctgaagggcg agggcagccg cggcaaggag   4200

gcaggggagg gcggcctacc gctgtgcggg cccacggaca agaccccact gctgagcggc   4260

aaggccgcca aggcccggga ccgcgaggtc gacctcaaga atggccacaa cctcttcatc   4320

tctgcggcgg ccgtgcctcc cggaagcctc ctcagcggcc ccggcctggc cccggcggcg   4380

tcctccgcag gcggcgcggc gtcctccgcc cagacgcacc ggtccttcct gggccccttc   4440

ccgccgggac cgcagttcgc gctcggcccc atgtccctgc aggccaacct cggctccgtg   4500

gccggctcct ccgtgctgca gtcgctgttc agctctgtgc cggccgccgc aggcctggtg   4560

cacgtgtcgt ccgctgccac cagactgacc aactcgcacg ccatgggcag cttttccggg   4620

gtggcaggcg gcacagttgg aggtaactag gatttctacc tcaaccgcga gacctatgca   4680

aggacggtgt ggaccaactc gcgcccgcgg catggtgccc gccggcctgc cgggctccca   4740

cccctggacg gcagaggcaa ggacggacgg gagctccact gtgaatcggc ggcacgcgcc   4800

gcaggaggct gggactggtc cagtttgtac tgtcgatagt tttagataaa gtatttatca   4860

ttttttaaaa agtataaaca attctgactt attttattcc atctaagtgg taaaaggcaa   4920

cttattgaga aatataaata tctatatatg agagctctat ataaagacac gtgtctgcag   4980

ggcgggcccg ccagcggatt cgccacagcc tgccccggtg ctatctcgtc cccaggcccg   5040

cgcctgcctc cacccgcttg gtgctgacta gacgctgaca acgccgaacc ccgttctcgg   5100

aaacgccgcc cggccggctc ccccgacgcg ctgctcccgt accaaaggca ggcccgtcgc   5160

caccacattc ctcggaggcc tccccgcggc ctgagcccct tcctgagcgc cctggcgcct   5220

gccctgagct cttcaccttt accccggcac tgtgaacccc cagactgttc accctccggg   5280

gcgtgggttg cgcccttgca tgtgaagggg cctgcgcggt gacgcagctg gccatgtgct   5340

gcgcgatggt gctgtgagga cggcgcgggc acgttgaaca agtgcattta cttttgtatt   5400

tctcggctgt ccatggctcg cagcatgccc tgcgatgcgg ggcaggcctg tcgtgggtcc   5460

cttggtgttt ctgtacagga gagagtcaca ctaatgagtg gcagtatttt atagagatgt   5520

gatgagaatt tataaatttc atagatttga cagcttttat ttttagatgg tataatgcac   5580

agtgaagagg aaagaaaagc gaggggaaaa aaccttattt attcaaacag tgcacaaaat   5640

ggccccagcg tcagccccga ccctagaccc ctcagttgca gctcccagca gcccagacag   5700

agctgccggc gcccctgcct gccccacatc ccttcctgtc agggccacgc ctggcaccca   5760

tcccttggag cctgtgctgg ttctcccagc tgctgtgggt gtgctggggc cagggtgcac   5820

tgctgaaacc tggcctctct ggccctaggc cccagggtga cgtcggcccc ccactctgca   5880

gccttggcgg gtgcctggga ctgggtgtgg aaggagagga gctgaggccg gggtgtagca   5940

ggcaggcagg gccactccag tgcttctgga gccctgagca gtcagggcct gggttgtctg   6000

agcagtggtg gctctgtgcc ctccctggag gatgggatct gggagtctga gctccccgca   6060

tctggccctg ggctgtgtgg cacttgctga gcccaccttc tcaagtgctt gctcctgtga   6120

gatggcatcg gggagcccct tccccaaggt gccacagatc caccctccag ggagctgcca   6180

gccctgtgtt ctggttccca agggcaggat ggacacacgt cacatcccta ccacgtggcc   6240

tccaaaggga gccacggagg aaaggcttct gtggttgcta ggtgggggag tcctgtgtgg   6300

gagggcctga agacccctgc ttgtgcctgg tgaggggggt gctgcctccc ccagccccca   6360

acaacctctc agacccccac cctccaacat agctgagttc tgaagatggt gctccggacc   6420

tgtcctctta agtggtgccc agtgccctcc ccaccccacg ttggtgctct cagctagaag   6480

gtgctgtgcc tctgcctgag ccccaagccc cgagcctggc cttcaggaca ggcagcctgc   6540

tctgtgtcgc cacgggccgg atacgccaca gggttgatgg cagagacggc cgagtccctg   6600

gtctagaaca agacacattc tttaaacact gtattacttc tgcctccctc taggtgacag   6660

tggcagtccg ggtgccatca cgggtcctgc agatggccat gcagggctcc tgcccacgca   6720

ggccaccgta tgttcaggac acgcactggg tctcagagcc actggcccag gcagaagtct   6780

ccttgagccc actgggtcat atgcgtgtca ccacacgtga actagtgtgg tggctgcctg   6840

cggacaccct cctgttctga gccctgggcc tgtgttcttc tcagacactc ccagactgag   6900

gggtggtgtg tggcgggtgg cagggtggct gtggagactg gggatctgga gcctggtgct   6960

ggcacctggc ctgagtttcc gtgggcagct ggcggggacc tgtgctgctg ctgctgactg   7020

tgggtgggcg ggcggcgcct gggagtggct cttgctcagg aattgatagg aaccctaaaa   7080

actaggatac cccctcctcg gcccatgagg cacgcacagt gacttattta agacttcccc   7140

cttaatttat ctgcccccag gatgcgtcag tctgttcagt ggtcagcagg ccccccaccc   7200

cccgccgact gccctcgcca tcgtggtcag acccccctcc caacacaaca cgctgctggt   7260

ctgtgtcagc ctttgtaacg tgggaggctc tgccgtgtct tccgggtgaa ctgtatttgg   7320

attgcgcgca ttgtcacggt ccgcccctgg gctgcaggcg ccccttcctc tgggcacccc   7380

tgcattctgc atccccacct ctagacgctg taataaacag actgttttca ctcggaaaaa   7440

aaaaaaaaaa aaaaa                                                    7455


<210>  665
<211>  2517
<212>  DNA
<213>  Human

<400>  665
gtgcgctgaa cgccccatat ccgggttccc gccgcctcca ccgccaccgc ctcagccgcc     60

tcgcacattt agtcttgccg ggagtggtgt gattcccgac caagatggcg gccgtggggc    120

gagtcggctc cttcggttct tctccgccgg gattatcctc gacttacact ggcggcccct    180

tgggcaacga gatagcgtcg ggcaacggtg gcgccgcggc aggcgacgac gaggacgggc    240

agaacctttg gtcctgcatc ctcagcgagg tctccacccg ctcgcgctcc aagctccctg    300

cggggaagaa cgtgctactg ctgggtgaag atggagctgg aaaaacaagc ttaataagaa    360

aaattcaggg aatagaggag tataagaaag gaagaggatt ggaatatttg tacttaaatg    420

tgcatgatga agacagggat gatcaaacaa gatgtaatgt ttggatctta gatggagacc    480

tatatcacaa aggcctcctt aaattttcac tggatgccgt atctctgaag gatactctag    540

ttatgctggt tgttgacatg tcaaagcctt ggactgcttt ggattcttta cagaaatggg    600

caagtgttgt tagagaacat gttgacaaac tgaaaatccc tcctgaagaa atgaaacaaa    660

tggaacaaaa gttgattaga gacttccaag aatatgtaga gccaggagaa gacttcccgg    720

cttctcccca gagaagaaat actgcgtcac aagaagacaa agatgacagt gtagttttac    780

ctctgggtgc ggatacactt acacataact tgggcattcc agtactagta gtttgcacaa    840

agtgtgatgc cattagtgta ttggagaaag aacatgacta cagagatgaa cattttgatt    900

ttattcagtc acatatccgg aagttttgtt tacagtatgg tgcagcactt atttacactt    960

cagtaaaaga aaacaaaaat atagacttag tatataaata catcgttcag aaactatatg   1020

gatttcccta taagattcct gctgttgttg tggaaaagga tgcagtattt attccagcag   1080

ggtgggataa tgataagaaa ataggaatat tacatgaaaa ttttcaaaca ttaaaagcag   1140

aagataattt tgaagacatc ataactaaac cacctgttcg aaagtttgta catgagaagg   1200

aaattatggc agaagatgat caggtgtttc ttatgaagct acagtccctt ttagcaaagc   1260

aaccaccaac tgcagctgga aggcctgtgg atgcctcacc aagagtccca ggaggctccc   1320

cacgaacacc aaatagatct gtatcatcta atgttgccag cgtgtcaccc attcctgctg   1380

ggtcaaaaaa aattgatcca aacatgaaag ctggagctac aagtgaaggc gttctggcaa   1440

atttcttcaa cagtttgttg agtaaaaaga ctggctctcc aggaggccct ggtgtgagtg   1500

gtggtagccc tgcaggtggg gctggaggtg gaagcagtgg tttaccacca tccaccaaaa   1560

agtcaggcca gaagcctgtc ttagatgttc atgcagaact agacagaatt acacgaaaac   1620

cagttacagt ttctcccaca acacctacat ctcctacgga aggagaagct tcttgaagat   1680

accaaataaa gccatttatt ctgttttctg ggataatgta aacatgcctc tgccttttcc   1740

ttcaaaagtg gaattagaaa gctggagtgc ttcttcagat ggactaaatt tatgtcgtgt   1800

gtgtgtgtgt gtgtgtgtgt ggttacccat tttttagaag gagccgtaca gaagaaaaat   1860

tattctacat tatgtaggat tgctgtttgc attgccattt tgcataagaa agtaattttt   1920

gattttgaaa atctcaaaac ttttagatct gaaatacagc catgtgatcg atcatattct   1980

aaaggctatt taaaacatgt aaaaggattt ggggaacggc agaaaacatg cagtttgggc   2040

atttgactga cttggaagtc taagcttatt ttagttataa ctattaaaat catttttaaa   2100

aatttgttag ttttgctgac agagaaaaat cgtcagttgt cagattttgc acaccacaat   2160

aaatgtacca ccacacacgg aatatgctaa gaaaactatc agatagcgtt tgatacacta   2220

gtcattgtct caatcactga tcctgtaagt tgtcatcaaa atatgattta gaaatattgg   2280

ccaaggtgtt gctttaactg aggagaaaag aaagcacact gcctaaatgt gtaaaagaaa   2340

aatgcagagg ttattaaaat gtaaagaagt aacaatcttt ggatttgtct atacatatat   2400

atatatatat atggctttgc cttaatatac cccctttttt gtttgtgact ttcaactgta   2460

atcagttaat aaagtattta ttctctgcat tcaggttcaa ataaaaaaaa aaaaaaa      2517


<210>  666
<211>  1313
<212>  DNA
<213>  Human

<400>  666
tcgcgcccgc ttttctctcg ggtgatccgg ccgagtggcc ctgggttagc agctgctgca     60

tttccccggc tggctgcggt cactggtggc agtgctcagg cgcccgccgc ccttgacctt    120

cggccccgcg agctctaacc ctacagcgca ggaagatcgg ccgccgcggc caggctctga    180

tgctggtgtc tggtagaaga aggttactca cagttctgct gcaggctcag aagtggccct    240

ttcaaccctc cagagacatg agactagtgc agttccgggc accccacctg gtggggcctc    300

acttgggcct ggagacaggg aatggtggag gggttatcaa cctcaatgcc tttgacccca    360

cactcccgaa gacgatgacg cagttcctag agcagggaga ggccaccctc tcagtggcaa    420

gaagagccct ggctgcccag ttgccagtcc taccacggtc ggaggtaacc ttcctggctc    480

cagtcacacg accagataag gtggtgtgtg tgggcatgaa ttatgtggac cactgcaaag    540

aacagaacgt gcccgtgccc aaggagccca tcatcttcag caagtttgcc agctccatcg    600

tggggcccta tgatgaggtg gtcctcccac cacagagcca ggaggtagat tgggaagtgg    660

agctggccgt ggtcattgga aagaaaggca agcacatcaa ggccacagat gctatggccc    720

acgtggccgg cttcactgtg gctcatgacg tgagtgctcg tgactggcaa atgagacgta    780

atgggaaaca atggctgctg ggaaaaacct tcgacacctt ctgccctctg ggccctgcct    840

tggtgaccaa ggacagtgta gcagatccac acaacttaaa gatctgctgc cgagtgaatg    900

gggaagtggt ccagagcggc aacaccaacc agatggtatt caagacagag gacctgatag    960

cctgggtctc ccagtttgtt accttttacc caggggatgt catcctaact gggacccccc   1020

caggtgtcgg tgtattcagg aaacctcctg tctttctcaa gaagggggat gaagtccagt   1080

gtgagattga agaactaggt gtcatcatca acaaggtggt gtgatggctc ctgcacaggc   1140

cctgcacata ggatgagggc atctgctccc actcagccta gcccagggaa aggcccagtg   1200

acaggtgtgg acaggtgcca gccctgcaag ccgcctcttc tcggtagaag ggagaaggac   1260

agagctctct tcaataaatt cgtcaggtca aagcagcaaa aaaaaaaaaa aaa          1313


<210>  667
<211>  3633
<212>  DNA
<213>  Human

<400>  667
cctctccagc cgcccgccct ccggccgcgt ccccgccggc cctgcagacg tggcggggcg     60

ggacccgctg ggcactcccg cgcgtactcg gccgcctgag cggctgtgga ttcccctcca    120

agtggaggag gatgggcagg ctggggatcc tggggcaaat ctctgctgtc gtcagcatct    180

gccacagtag gtcatggatt gacggcagtc aaggaaaaag caggagccac tctacggatt    240

catggtgtaa attctggatc ttctgaagga gcccaaccaa atactgaaaa cggagtccct    300

gaaataacag atgcagccac agatcagggc cctgcagaaa gcccacccac ttccccttca    360

tcagcctctc ggggtatgct gtctgccatc accaatgtgg ttcaaaacac aggtaaaagt    420

gtcttaactg gaggccttga tgcgttggaa ttcatcggca agaaaaccat gaatgtcctt    480

gcagaaagtg acccgggctt taagcggacc aagacgctca tggagagaac tgtttccttg    540

tctcagatgt taagggaagc taaggagaag gagaagcaga gactggcaca gcagctcacg    600

atggagagaa ccgcgcacta cgggatgctg tttgatgaat atcaaggctt gtcacacctg    660

gaagccctgg aaattctgtc caatgaaagc gaaagcaagg ttcagtcatt tttagcatca    720

cttgatggag agaagctgga actcttaaaa aatgacctaa tttccattaa agacatcttt    780

gcagccaaag aattagagaa tgaagaaaat caagaagaac aaggcttaga agaaaaggga    840

gaagaatttg ctcgcatgct tacagagctt ctctttgaat tacatgtggc ggccacacct    900

gacaaactca ataaggccat gaagagggct catgactggg tggaagagga tcaaaccgtg    960

gtgtcagtag atgtggcaaa agtgtccgaa gaagaaacaa agaaggaaga aaaggaagag   1020

aaatctcaag accctcaaga agacaaaaag gaggaaaaga aaactaagac catagaggaa   1080

gtatacatgt cgtccattga aagtctggcg gaggtaacag cgcgctgtat tgagcagctt   1140

cataaagtag cagaattaat tcttcatgga caagaagagg aaaaaccagc tcaggaccaa   1200

gcaaaagttc taataaaatt aactactgca atgtgcaatg aagtggcctc tttatcaaag   1260

aagtttacga attctttaac cactgttggg agcaacaaga aggccgaggt ccttaacccc   1320

atgatcagta gtgtattgtt agagggctgc aacagtacaa cgtacataca ggatgccttc   1380

cagctgctgc tgcctgttct gcaggtctca catatccaga ccagttgttt gaaagcacag   1440

ccgtgacctg gccagactcc atctagttaa aggagacagc tggccgcctt gcctcaatat   1500

gtaccattta aggggatgtt ctctgtgcgc ctggccacag acatccattt gaggacacta   1560

caagcaattt tgcacagaca atattgagaa tgcaaattta gagagagtta tcatttctct   1620

caatgtgtat aattgttttt acaaacaatt gtgttttctt tatgttaatt taaacttaca   1680

cagcttatat tgaaaatttc ctttcatctg aaatttattt acaaatattc gtgttcattt   1740

tcctggttaa gcatgctata tttagaaact catggggaga ccttagactt ttgtttaatc   1800

ctttatgttt caacctttaa atgttccatt cttatagtat tactttaaat caattctaaa   1860

actgaacttt gttttgttac ataaatgtcg caggcaaaaa taacactact tatagatttt   1920

acctattatg gtaaaaaata ggaacatatt gtcattcttt tttttttttt ttttttgaga   1980

cagagtctca ctctgtcgcc aggctggagt gcgttggcac aatctcggct cactgcaacc   2040

tccgcctcct gggttcaatc gattctcctg cctcagcctc ctgagtagct gggactacag   2100

gtgtgtgcca ccacgcccag ccaatttttt ttgtattttt agtagagaca gggtttcacc   2160

atgttggcca ggatggtctc gatctcctga cctcgtgatc tgcccgcctc agcctcccaa   2220

agtgctggga ttacaggctt gagccaccgc gcccggccgg tcattcattc ttgcaacaag   2280

catttattga gcacctactg tgtgctcaca gtaaagaaac gtgatcttat cccagtagag   2340

gtagatattc tgaaaaagaa taattcttaa actgcttaaa acaggggtcc ccacccccag   2400

gccacagacc agtaccagtc cgtggcactg gttaggaacc aggccacaca gcagggggtg   2460

agcggtgggt gagtgagcac agcttcatct gtatttacag ctgctcccca gagcttgcat   2520

tactgcctga gctctgcctc ccgtcaggtc agcagcagca ttagagtctc atgggagtgc   2580

gaaccctgtt gtgaactgca catgcgaggg atctaggttg tgcactcctt atgagaatct   2640

aatgcctgat gaatctaatg cctcatgatc tgaggttgaa tagcttcgtg ccgaaaccat   2700

cccccacccc catcccgcta ccccgagtcc gtgaaaaaat tgtcttccat gaaaccggtc   2760

cctggtacca gaaaggttgg ggaccactgg cttaaaatac caataaattt ttgaacctta   2820

aaaactttga agaacaaggt aaattggtgt tttatttaat gtcctaccct ttaatttgtt   2880

gcattttcct atactcttta cactatttta tcccaaacta tgtatatgag gtgaaaatat   2940

atatgaaaag ggatactgaa gaatatttag tttaaaatta atttcttacg atcacgagca   3000

catggtggca taattacaaa gcttggaagt attcaaatag aaaatcaaag gtgtttcaat   3060

acagtagaat cccaggactg cattttaaaa tcgcctcaca gatcacactc gctggtggca   3120

aatatcatca tcgttgctaa aggacagaaa atactgatgt gtgttttaac taactggtat   3180

attgatccat gggaggctgc acagaagacc ctgcggccag gaggggcatt gtcagtggct   3240

gcttctcctg agctccacgc cttcattgca gctgcatgtt cgatacaata cacctgcttc   3300

acagccccat ggacatccct acaggtactg tcatgtgaag ccttgcctag tagttctctc   3360

cagggcaaat gaagctcaca gttttgcaag gtggaaacct cttattcaca tttgctttga   3420

ttccccgatg gagtagactg cctttgttcc atacaggcaa agtaaggata ttttaatatc   3480

atcctacttc ttattagcat ttcatttgtc tatgtactgt atttcatttg tatgtctcct   3540

gaaacatcca aatagagaac ataagaacac tttatgtaca atctggaaaa aaattacctg   3600

agaaatcaat taaagatttt tccccttttc tga                                3633


<210>  668
<211>  3184
<212>  DNA
<213>  Human

<400>  668
atccaatgaa ggttactggc tgagcgggga caccttctca caggactgga gagagaatgc     60

ggggcagctg ggcagggctc acttccagcc gcctgtcaca gtactgggag taagaggtga    120

cctatttatt tttagaaggg ggcagtgata ataacccagc tcctagcttc attcaaggga    180

ggcaggcgct ttggaagttt gtaaacacca actttctgag taagggagga gcactttttt    240

tccaaaaagg aaagaacgtc tctactgggt ttttttcctc ctgatattca gcattagagt    300

agaaaagaaa ctattgtttg gccacattag ccgtggttag caggtgctgc agcctttgcc    360

actgttatta tttttaaagg gcagaaatgc ctgaaggtga agactttgga ccaggcaaaa    420

gctgggaagt tatcaattcc aaaccagatg aaagacccag gctcagccac tgtattgcag    480

aatcatggat gaatttcagc atatttcttc aagaaatgtc tctttttaaa cagcagagcc    540

ctggcaagtt ttgtctcctg gtctgtagtg tgtgcacatt ttttacgatc ttgggaagtt    600

acattcctgg ggttatactc agctatctac tgttactgtg tgcatttttg tgtccattgt    660

ttaaatgtaa tgatattgga caaaaaattt acagcaaaat taagtcagtt ctgctgaaac    720

tggattttgg aattggagaa tatattaatc agaagaaacg tgagagatct gaagcagaca    780

aagaaaaaag tcacaaagat gacagtgaat tagacttttc agctctttgt cctaagatta    840

gcctcacggt tgctgccaaa gagttatctg tgtctgacac agacgtctca gaggtatcct    900

ggactgataa tgggaccttc aacctttcag aaggatacac tccacagaca gacacttctg    960

atgatcttga ccgacccagt gaggaagttt tctctagaga tctttcagat tttccatctc   1020

tagaaaatgg catgggaaca aatgatgaag atgaattaag ccttggtttg cccactgagc   1080

tcaagagaaa gaaggaacag ttggacagtg gtcacagacc aagcaaagag acgcaatcag   1140

cagctggtct cacccttcct ctgaacagtg accaaacctt tcacctgatg agcaacctgg   1200

ctggggatgt tatcacagct gcagtgactg cagctatcaa agaccagtta gagggtgtgc   1260

agcaagcact ttctcaggct gcccccatcc cagaagagga cacagacact gaagaaggtg   1320

atgactttga actacttgac cagtcagagc tggatcaaat tgagagtgaa ttgggactta   1380

cacaagacca ggaagcagaa gcacagcaaa ataagaagtc ttcaggtttc ctttcaaatc   1440

tgctgggagg ccattaatct aggaatcagc ttgcaacaga gcacaaaaaa caccaaaaaa   1500

atttcaaaca agaaaaaaaa aaaaaaaagg aaaagaaaaa aattgaactg taagctttaa   1560

tgattacttt agatttgttt tattttccct cctgcagtga attaattgga tatatatcag   1620

ctgacactga tagattgata tttctgatcg ttatttttgt gtaataagca tggaaatgaa   1680

ctttatacac accactgtgt tgtcagagat aaatattagg ggttgttttt aaagcaaaaa   1740

gaaaaaaaca aaaaccaaac tattaaaatc ctcctataaa tattcttttt ctttacagtt   1800

tttcaagcat gcaaaacagt ttattgtaac ttactgaaaa atattaacaa ttaattgtga   1860

atacatgctg ttaccagctt ccttattcct aatacctgga aaattttttt ttcaacggat   1920

agattttgat gtaaaaaaga ccgaaattat caaggtatct tagttgaagg acttgggaaa   1980

tactatcaaa attaatttct taggaaaaaa tttaaaagta tatttaagta ctctggatag   2040

actgaaacgt ttccatgtta tttctgcagt tgtagactta ggcttatttg taaagaagca   2100

tgctccattg actgccatct ctagtcttgc agtgggtggt attaacccat agaaagcaag   2160

cagttgtgta tcacatagac aatggttatg atgtaaacag attcagttgt tttgttgttc   2220

attcgtcata tgtttgtgat agggatgttg ggagcacagc tctattctgc ctgctcagac   2280

ttaagttaga cccttatctt ttatattatg tcatgaaaaa agtctcctaa aattgtgaaa   2340

ctagttcttg atgagtgatg tgatcatcag caataaagat ataataactc tgttttctta   2400

gcctgtatag aggagaggaa cttgcttggc tttaaaatat atttatttgc catttaagta   2460

taaatatgga atctgtttct tattgggaag atagaatata tatattttcc tttaaacttt   2520

ttaaggtcac ttttaaataa ccaaatttga tttatggttt ttaacaaagg actaaagagc   2580

tgaaaccaac ctagttttgt ttttgtgata taaactttaa gtgtcgaggg accatgccag   2640

caactaccaa aaatctctta aatcttcagg tacagctggc attttggcag atgcatagag   2700

acatctgaga ccctcagaaa ggaaggataa tccaagaata taggaaatct gtgttctctt   2760

cctttcattt tatcccttat atttctaaag actaattata agtaatctga cattttaatg   2820

tagctactct tatttatttt ttctttctga ggtattaaaa tatctggact gagttttgcc   2880

aaatgttaaa gggagaagag ttactgaaga ctttgaacac ttgctttttg tgattgctta   2940

tgtcattagt gcctcatgac tgtgtttgat gtcctttatt gatacaaagt gagcctgtgc   3000

cttcattatc ttgcccattt taatacaaat ggaaacctgg tgtttgaaaa tctctgaact   3060

gtgtgggttt tggaggaata tacctgaatt ttattcaata acagtttctg gacaggaaga   3120

aaaatacagt tacatattta taaaatagtc gttatcagta aaaaaaaaaa aaaaaaaaaa   3180

aaaa                                                                3184


<210>  669
<211>  1554
<212>  DNA
<213>  Human

<400>  669
acacacaccg cccaagcccg gacggtggcc gcgaagctag ggccaccatg gcggaccgca     60

ggcggcggct ccggccgggg acgttggccc cggtgcgcga gggcgtgaac tgcaggtcca    120

gatgtttcac aaagcacaag aacgggctga agttccccac ctctctgcac agccggcagt    180

tggtatttcc aagaaagggg ctggacgact tcaggaaggg ctgcccgcct tgcactggtc    240

tggtgactca ggtccctgtg gagggctttc tgccccagat ttatcacaga gctccccaac    300

tggccccaaa gaagaggcag atcaagctgc tcaaggaagc agacgtgctt tccaagctct    360

cgccagccca gcaggctcgg aaggcattcc tggaggacgt ggaggcccac ctgaccccac    420

atcccttagc gctctacctg aatctggaag aagctatgcc catagagctc ttatcaaagg    480

tgctggaagt gcttgatcct gaccggaagc tggaggacac atgggcttat tgtcaggaca    540

ccaggaaagg aatgaaggaa cccacgaagc ttttaaaaaa acattctacc caagtctacc    600

tgggaccttc caagaagacg tctgtgtcaa acgcaggcca atggctttat gaagaaaagc    660

cacataaaat ggatttgctc catgaaaatg gtcctcgtcc tggtcttcat gaaaatggaa    720

tttcggacat cgatgaagag ttcatcttga aacagtttga cattgactat gagaccaaac    780

caagccatga tgcgctccac acgatgaagc taaatcaggt tcctctggag ctaaagcgta    840

gtgtggggct cagtaaactg caggagacag agttcttcca gaaactaggc tatgagagga    900

aactccagaa accacagaat ccttataagc caaagtgggt gaagatgagg tatggagcat    960

ggtatttgaa ccccaagttg tggaaaaagc aaagagtaga cgagcctctg gttgaccctg   1020

aggtctcaca taaggctcaa gaggagaatt ttaaaaagga gctgcaggaa caggaggagt   1080

tacttgcaga ccttcacgga acagttgcct ttaaggattt cattctaagc aggggctaca   1140

ggacgccacg tttccttgag aatatgtata tcgggaagga atgtaaacgt gcatgtaata   1200

agactcctat aaaacgaact caagcataga agaatcgtag gagaatgatt aggcagattt   1260

tattactacg tacttggcta tttctctgtc tccttttaaa gattaaacag agtttatgat   1320

gagtgtccca ctgtggatgt tcaactttga cttggcaaca tctgtaaatg taatacctga   1380

tggttataag catttctcaa tggatttctg cttcagttaa tcaacatttt gtatacttta   1440

tcacccatga gatcaatatt cacatgtaat cttctcatat ttttgtggca cgtgaatatt   1500

atataggtat atcaactatt ggtaaaaata aataaaggca taaataaaaa caga         1554


<210>  670
<211>  2948
<212>  DNA
<213>  Human

<400>  670
gcgggccggg gcggggcctc gcttcccagg caagcgcagg tccaggcggt gcagcttggg     60

cggcccagcg gatcgtgccg cggcggccga gcgcagctac aggagggtgt ccagaagcca    120

caagccatgg ctgtggggaa catcaacgag ctgcccgaga acatcctgct ggagctgttc    180

acgcacgtgc ccgcccgcca gctgctgctg aactgccgcc tggtctgcag cctctggcgg    240

gacctcatcg acctcgtgac cctctggaaa cgcaagtgcc tgcgagaggg cttcatcact    300

gaggactggg accagcccgt ggccgactgg aagatcttct acttcttacg gagcctgcac    360

aggaacctcc tgcacaaccc gtgcgctgaa gaggggttcg agttctggag cctggatgtg    420

aatggaggcg atgagtggaa ggtggaggat ctctctcgag accagaggaa ggaattcccc    480

aatgaccagg tcaagaaata cttcgttact tcatattaca cctgcctcaa gtcccaggtg    540

gtggacctca aggccgaagg gtattgggag gagctgatgg ataccacacg gccggacatc    600

gaggtcaagg actggttcgc agccaggcca gattgcgggt ccaagtacca gctgtgcgtt    660

cagctcctgt cgtccgcgca cgcgcctctg gggaccttcc agccagaccc ggcgaccatc    720

cagcagaaga gcgatgccaa gtggagggag gtctcccaca cattctccaa ctacccgccc    780

ggcgtccgct acatctggtt tcagcacggc ggcgtggaca ctcattactg ggccggctgg    840

tacggcccga gggtcaccaa cagcagcatc accatcgggc ccccgctgcc ctgacacccc    900

ctgagccccc atctgctgaa ccctgactgg taaacaactg ctgtcagaaa agggctgggc    960

ttgggaaggg gaggtggagg ccaggtgtcc ccagacctct aacccttgcc cctagcagcc   1020

tcttctttgt ggagcctctc agtgtgggca gccctcgcat gctggggtcg ggccagctct   1080

ccccgaaagg tcttgacctg aatgatggcc ggggaagcct gcgtgtgccc ctttcagaga   1140

cggagcacct gagatgtggg aggtgcagca tgttcccctg ggcccctcag aaagtcgagc   1200

ttggaggcca gcctggatct gtctctccct tcccctcctg ggaccattct acctgtgttc   1260

tttgaccctc ggagcaggga caggcaagac aactggcaag cttgcagctg ccctgatggt   1320

gcaggtgcag ggaggtgacc atgtaactct gaccaatctg ggaagtggag ggtgggctca   1380

tgggccgtgc tctgcccctg tctgctgctc ccagtctctc gctctgcctg cctgctcaga   1440

agaggtggct ttggcccaga ggctcaggcc gggactgaga tggacagacc cagggtgggg   1500

tggggtccag gtcgggtgtg gactgtcctc actgtcagtg gagccccaga agctagatgg   1560

gtaccaggtg gggttaggtt cccagaggac tgagggaatc ctgtacagga tgtcccaggg   1620

tagatgggga gcaggattgg gacctgctct gacagctgga cacatgagcc ctggatgagt   1680

atggtagggg gtttgaagaa tcccctgtcc acctcccaaa tccaggcccg gccccctctg   1740

gcttggagag cattccaagc ccccacccca cccctagaac tgccattccc aagacctctg   1800

tctcccagcc aaccaccctt ggaacttgcc tcttgtcctg ctggaaagat agcagtgttc   1860

tcctgacttc gccctactgc atgcagccaa ataaaaggtg tgcccagtct aacctgtgcc   1920

ctgtggtttc tggaaggaaa ggcagacttt aggtggtcct gcctggacct gcagatggta   1980

caatggcatg gcttctgtct aaggtacaga ggggttggca tttcaggaac caggccatca   2040

cagaaacagg ttcatgggca gacccctcag tgagctgcag gtatctcacc tggcagccgt   2100

ccagtactgc tggcttcctc tggaggccca gccacaggct ggggttgggg tgtgtggaca   2160

tctctgggca gctcttgagt ccaccttgtg ccagatcagc agtgccaccc aggctctgcc   2220

tcctggtgtt actctttgcc aacagcttta cggacattgg atgaagccga agcatttaga   2280

atggtgcctg gcacacagtt ggtgcgtgat atggttaagc tttgtgtccc cacccacatc   2340

tcatcttgaa tggtaatcct gggtgtttag ggagagacct ggtgggaagt gattggatta   2400

tgggagcggt tttcccccat gctgttctca tgatagtgag tgagttctca cgagatctga   2460

tggttttaca agtgacggtt tccccggctc cctcctgccg ccatgtgaag aaggtcgttg   2520

cttccccttc accttccacc accatgattg taagttcctt ttttcttttc ttttcttttt   2580

tttttttttt tttttgagat ggagtctcgc tctgtcgccc aggctggagt gcagtggcgc   2640

aatctcagct cactgcaagc tctgcctccc aggttcgcgc cattcacctg cctcagcctc   2700

tggagtagct gagactacag gcgcccacca ccatgcccgg ctaattttgt ttgtattttt   2760

agtagagatg gagtttcacc atgttggcca gggtggtctc aatctcctga cctcgtgatc   2820

cacccacctc gacctcccaa agtgctgaga ttacaggcgt gagccaccgc gcccagcgat   2880

tgtttcttga ggcttcccca gccatatgga actataagtc aattaaacct ctttcctttt   2940

ataaatca                                                            2948


<210>  671
<211>  2888
<212>  DNA
<213>  Human

<400>  671
cccgagcctc tctccctggc caggccccag gtctcgcagc cagggatgga gatgggggga     60

gggggaacct agagttcttt gtagtgcctc cctcagactc taacacactc agcctggccc    120

cctcctccta ttgcaacccc ctcccccgct cctcccggcc aggccagctc agtcttccca    180

gcccccattc cacgtggacc agccagggcg ggggtaggga aagaggacag gaagaggggg    240

agccagttct gggaggcggg gggaaggagg ttggtggcga ctccctcgct cgccctcact    300

gccggcggtc ccaactccag gcaccatgtt ccccgcgggc ccccccagcc acagcctcct    360

ccggctcccc ctgctgcagt tgctgctact ggtggtgcag gccgtgggga gggggctggg    420

ccgcgccagc ccggccgggg gccccctgga agatgtggtc atcgagaggt accacatccc    480

cagggcctgt ccccgggaag tgcagatggg ggattttgtg cgctaccact acaacggcac    540

ttttgaagat ggcaagaagt ttgattcaag ctatgatcgc aacaccttgg tggccatcgt    600

ggtgggtgtg gggcgcctca tcactggcat ggaccgaggc ctcatgggca tgtgtgtcaa    660

cgagcggcga cgcctcattg tgcctcccca cctgggctat gggagcatcg gcctggcggg    720

gctcattcca ccggatgcca ccctctactt cgatgtggtt ctgctggatg tgtggaacaa    780

ggaagacacc gtgcaggtga gcacattgct gcgcccgccc cactgccccc gcatggtcca    840

ggacggcgac tttgtccgct accactacaa tggcaccctg ctggacggca cctccttcga    900

caccagctac agtaagggcg gcacttatga cacctacgtc ggctctggtt ggctgatcaa    960

gggcatggac caggggctgc tgggcatgtg tcctggagag agaaggaaga ttatcatccc   1020

tccattcctg gcctatggcg agaaaggcta tgggacagtg atccccccac aggcctcgct   1080

ggtctttcac gtcctcctga ttgacgtgca caacccgaag gacgctgtcc agctagagac   1140

gctggagctc ccccccggct gtgtccgcag agccggggcc ggggacttca tgcgctacca   1200

ctacaatggc tccttgatgg acggcaccct cttcgattcc agctactccc gcaaccacac   1260

ctacaatacc tatatcgggc agggttacat catccccggg atggaccagg ggctgcaggg   1320

tgcctgcatg ggggaacgcc ggagaattac catccccccg cacctcgcct atggggagaa   1380

tggaactgga gacaagatcc ctggctctgc cgtgctaatc ttcaacgtcc atgtcattga   1440

cttccacaac cctgcggatg tggtggaaat caggacactg tcccggccat ctgagacctg   1500

caatgagacc accaagcttg gggactttgt tcgataccat tacaactgtt ctttgctgga   1560

cggcacccag ctgttcacct cgcatgacta cggggccccc caggaggcga ctctcggggc   1620

caacaaggtg atcgaaggcc tggacacggg cctgcagggc atgtgtgtgg gagagaggcg   1680

gcagctcatc gtgcccccgc acctggccca cggggagagt ggagcccggg gagtcccagg   1740

cagtgctgtg ctgctgtttg aggtggagct ggtgtcccgg gaggatgggc tgcccacagg   1800

ctacctgttt gtgtggcaca aggaccctcc tgccaacctg tttgaagaca tggacctcaa   1860

caaggatggc gaggtccctc cggaggagtt ctccaccttc atcaaggctc aagtgagtga   1920

gggcaaagga cgcctcatgc ctgggcagga ccctgagaaa accataggag acatgttcca   1980

gaaccaggac cgcaaccagg acggcaagat cacagtcgac gagctcaagc tgaagtcaga   2040

tgaggacgag gagcgggtcc acgaggagct ctgaggggca gggagcctgg ccaggcctga   2100

gacacagagg cccactgcga gggggacagt ggcggtggga ctgacctgct gacagtcacc   2160

ctccctctgc tgggatgagg tccaggagcc aactaaaaca atggcagagg agacatctct   2220

ggtgttccca ccaccctaga tgaaaatcca cagcacagac ctctaccgtg tttctcttcc   2280

atccctaaac cacttcctta aaatgtttgg atttgcaaag ccaatttggg gcctgtggag   2340

cctggggttg gatagggcca tggctggtcc cccaccatac ctcccctcca catcactgac   2400

acagctgagc ttgttatcca tctccccaaa ctttctcttt ctttgtactt cttgtcatcc   2460

ccactcccag ccccttttcc tctatgtgac agctccctag gacccctctg ccttcctccc   2520

caatcctgac tggctcctag ggaaggggaa ggctcctgga gggcagccct acctctccca   2580

tgccctttgc cctcctccct cgcctccagt ggaggctgag ctgaccctgg gctgctggag   2640

gccagactgg gctgtagtta gcttttcatc cctaaagaag gctcctttcc ctaaggaacc   2700

atagaagaga ggaagaaaac aaagggcatg tgtgagggaa gctgcttggg tgggtgttag   2760

ggctatgaaa tcttggattt ggggctgagg ggtgggaggg agggcagagc tctgcacact   2820

caaaggctaa actggtgtca gtcctttttt cctttgttcc aaataaaaga ttaaaccaat   2880

ggcaaaaa                                                            2888


<210>  672
<211>  4127
<212>  DNA
<213>  Human

<400>  672
gtgctccgct ggttgaaagc ggatccgggc tggaggcggt gtcacggtgt atgaatattg     60

attacgcgtc gcagcgccca gggcccagcg cccagcctcc agtgcccgcc cctctcggcc    120

gcccgacgct ctctgctcgc gcttgggctc gcgatgggga agaagtcccg ggcggtaccc    180

ggccgtaggc ccatcctgca actctctccg ccgggtcctc ggggcagcac gccgggccgg    240

gacccggagc cggaacccga cactgagccg gactcaaccg cggcggtccc cagccagccc    300

gccccgtcgg cggcgacgac caccaccacc gcggtgactg ccgccgcggc ctcggacgac    360

tcgccttcag aagatgaaca ggaagcggtg caggaggttc ctagagttgt tcagaatcct    420

ccaaaaccag tcatgaccac tagacccaca gctgttaaag caacaggcgg tctatgcttg    480

cttggtgctt atgctgacag tgatgacgat gacaatgatg tttccgaaaa actagcacaa    540

tccaaagaga caaatggaaa ccagtcaact gatattgata gtacattggc caacttccta    600

gcggagatcg atgccataac agctcctcag cctgcagctc ctgtaggagc ttctgctcca    660

cctccaactc cacctcgacc agagccaaag gaagcagcaa catctaccct ttcttcttct    720

acttcaaatg gaacagactc cacccaaaca tctggttggc aatatgatac tcagtgttca    780

ctggcaggag tcggaattga gatgggcgat tggcaggaag tctgggatga gaacacggga    840

tgttattatt attggaatac acaaacaaat gaagtgactt gggagttacc ccaatatctt    900

gccacacagg tacagggatt acagcattac cagcccagtt ctgtgccagg tgctgaaact    960

agttttgtgg taaatacaga catatattct aaggagaaaa cgatttctgt ttccagtagt   1020

aaaagtggac cagtcatagc caagcgagaa gttaaaaagg aagtaaatga aggaattcag   1080

gctctctcaa atagtgagga ggagaagaaa ggggtggcag catcgctgct tgctccttta   1140

ttgcctgagg gaataaaaga agaagaagag agatggagaa gaaaagtaat ttgtaaagag   1200

gagccagttt cagaagtaaa agaaacaagt acaacagtag aagaagcaac aacaatagta   1260

aagccacagg aaattatgtt ggacaatata gaagaccctt ctcaggagga tctttgcagt   1320

gttgtccaat ctggagaaag tgaggaggaa gaggaacaag atacccttga actggagcta   1380

gttttggaaa ggaaaaaagc agagttgcga gccttggagg aaggagatgg tagtgtgtca   1440

gggtctagtc cacgttctga tatcagccag ccagcatctc aagatggaat gcgtaggctt   1500

atgtctaaaa gaggaaaatg gaagatgttt gttcgagcta ccagtccaga atctaccagt   1560

aggagttcta gtaaaactgg acgagatact ccagaaaatg gagaaactgc aattggtgct   1620

gaaaattcag aaaaaataga tgagaattca gataaagaga tggaagtaga agaatctcca   1680

gagaaaataa aagtacagac aacaccaaaa gtagaagaag aacaggattt gaaatttcag   1740

attggagaac tggcaaatac cctgacaagt aaattcgagt ttctaggcat taatagacaa   1800

tccatctcca actttcatgt gctgctctta cagactgaga ctcgaattgc agactggcgg   1860

gaaggggctc ttaatggaaa ctaccttaaa cgaaaacttc aggatgcagc agaacaacta   1920

aaacagtatg aaataaacgc cactcctaaa ggctggtcct gccactggga cagggatcat   1980

agacggtatt tctatgtaaa cgaacagtcg ggcgagtctc agtgggagtt tccagatggt   2040

gaagaggaag aagaagaaag ccaagcacaa gaaaatagag atgagactct tgccaaacag   2100

accttgaaag acaaaactgg cactgattca aattcaacag aatcctctga aacttccaca   2160

ggttctcttt gtaaagaatc cttttctggt caagtttctt cttcatcact catgccactt   2220

actccattct ggaccctcct tcagtcaaat gttcctgtgc ttcaacctcc attacccttg   2280

gaaatgccac cacccccacc tccacctcca gaatcacctc caccccctcc tccaccacct   2340

cctcctgcgg aagatggtga gatccaggag gtagagatgg aggatgaggg aagtgaggag   2400

ccccctgccc caggaacaga ggaagatacc cctttgaaac cttcagcaca aaccacagtt   2460

gtaactagcc agagttcagt tgattccacc atctctagtt cttcttccac taaaggaata   2520

aagaggaaag ctacagaaat tagcactgca gtggttcaga ggtcagctac cattggcagt   2580

tctccagttc tctatagcca gtcagctata gctacaggtc accaggcagc agggattgga   2640

aaccaggcaa caggaattgg acatcagaca ataccagtta gccttccagc agcaggaatg   2700

ggtcatcagg ccagaggaat gagcctgcag tcaaattacc ttggactagc ggcagcacct   2760

gcaattatga gttatgcaga atgttctgtc ccaattggag tgactgctcc ctcattgcag   2820

ccagttcagg cccgaggtgc tgtgcctacc gctaccatta tagaaccacc accaccacct   2880

cctcctcctc ctcctccacc accaccagct cccaaaatgc caccacctga aaagacaaaa   2940

aaaggaagga aagacaaggc aaagaagagt aagaccaaaa tgccatcttt ggtaaaaaag   3000

tggcagagta tccagcgtga gttagatgaa gaggacaatt ctagttccag tgaagaggat   3060

cgggaatcaa ctgcacagaa gcgaattgaa gagtggaaac agcagcagct ggttagtggc   3120

atggcagaga gaaatgctaa ttttgaagcc cttcctgagg attggagagc aaggctgaag   3180

agaaggaaaa tggctccaaa cacatagttt ttaagttttt aaaacttttt tgtattattg   3240

tttgttttgt gttcagttca aagtcttaac cagttttatt gtcaaataaa ctataaatgt   3300

tatgggggag atcttataaa tttcctgggc aagagtgtat gcatacaaag ttttcacttt   3360

tgtgaaatgt aatttttctg tttttgcaaa gggatgaggt gattggaatt gctttgacca   3420

tgctgccttt attctcaaac tggcaaactt agcatgttag gtgtattaac ctcatcagtc   3480

ttgaagaaca tgtggctcat gagtataaca cttctgtaga ggactccctg acaaaagtga   3540

agaattaact tctcctccag aacaagtgca attcagaagg cagctctgca ttctaccttg   3600

cttgactgga attgtctgaa gctttttctg gcctcttttc tctagtcggc cacccctgaa   3660

gtgctgaggt ctaagtggtt tacctcgtgc tgatagatgg ccacactctt tagagtagtt   3720

ctcataagtt ctagaactgg tagctcggtc gtttcgcaca ctaggtggca tacaggcagc   3780

agcaggtgtt catatccttg attttgagaa tttcccctca agtatgtggc agtaaataca   3840

acaagacact ctatgtatta atgtctccat tgtcttaacc ctgttccaaa acaaaattca   3900

cctcctttct ttatgtgaat gtattctcca taaaattcca gtatttaaaa agcagtttac   3960

tgttctgtac tttctgttgt atcacaatca ggtaaaagtc actttaaact gaggaaacgg   4020

caaattgtgt tttaaagctc tttgtatttc tccagtttct gaccttgtaa atttgtatat   4080

atgcactaat aaagcttttt ttataatcct gaaaaaaaaa aaaaaaa                 4127


<210>  673
<211>  3207
<212>  DNA
<213>  Human

<400>  673
gctaagtcaa catataacag caaacttaca acaattattt aacattttta aagccatgaa     60

gaagggacag agcacggagc ggccggggag agcggcagag ccagaggcag aggcacggct    120

ggctccccgg gagggccctt gcggcgcggg gcgcagtgcc taggccgccc gggtctcctg    180

cgttgcgggg agcgcagcgc aggctctcgc ttgccatgag tcacctcttc gatccccggc    240

tgcctgccct ggccgcctcg cccatgctgt atctgtacgg tcccgagaga cccggcctcc    300

ctctggcctt cgcccccgcg gctgctctag ctgcctcggg ccgggccgag accccgcaga    360

agcctcccta cagctacatc gcgctcatcg ccatggcgat ccaggacgcg cccgagcaga    420

gggtcacgct caacggcatc taccagttca tcatggaccg cttccccttc taccacgaca    480

accggcaggg ctggcagaac agcatccgcc acaacctctc gctcaacgac tgcttcgtca    540

aggtgccccg cgagaaaggg cggccgggca agggcagcta ctggacgctg gacccccgct    600

gcctggacat gtttgagaac ggcaactacc ggcgccggaa gaggaagccc aagccgggcc    660

ccggggcccc ggaggccaag aggccccgcg ccgagacgca ccagcgcagc gcggaggcgc    720

agccggaggc ggggagcggg gcagggggct cgggccccgc aatctcccgc ctgcaggcag    780

cgcccgcggg cccctcgccc ctcctggacg gcccctctcc gccggcgccc ctccactggc    840

cggggaccgc gtccccgaac gaggacgctg gtgacgctgc ccagggcgca gcggccgtgg    900

cggtcggcca ggcagcgcgc acaggggacg gcccggggtc ccctctgcgc cccgcctccc    960

gcagctctcc gaagagctcc gacaagtcca agagcttcag catagacagc atcctggcgg   1020

gaaagcaggg ccagaagccg ccttcagggg acgaactcct agggggtgcc aagcctgggc   1080

ccggcggccg tctgggtgcc tcgctcctgg ccgcctcctc cagcctccgt ccgcctttca   1140

acgcttccct gatgctcgac ccgcatgtcc agggcggctt ttaccagctc gggatcccct   1200

tcctctctta tttccccctg caggttcccg acacggtact ccacttccag taaagcaaac   1260

aatggcacgg ttcttctccc ggcccagcct gagcctccgc tgagcgaaag gccacagctc   1320

ccaccggcgg aggattttaa aatgatcttt gcctgggtcg gcctgtgggt tcagggaagt   1380

gttaccaacc attgcgcgca ggtgggcgcg ctcgcctgcc ttctccgaag caaacttttc   1440

ccagcaactg ggagcagcta cggagactta aaagatcccc gcggggtcgt gggcaccgca   1500

cgtgggccct gcagggacct ccaccgcggg agattccttg acgtttgacc tgtctaatgg   1560

agtgtggtct tcagccgccc accgcaggtc ctgcgagtcc cgggcatgca agggcccgca   1620

gaccacccaa ggcaggcctt acaggtgcag ttgaggtcct ttcgaccggg gacccccgta   1680

tgaccgtcgc ctgcttcgct gttgccgtgt ggctcaggcc ttggttttga gcccatctgg   1740

gtggtgggtg gtcacagctg ggtttgttcc tgacttgaag ttgtggaggt gccgggggtg   1800

accccgggtt ttcaggtttt ctgagagatg tagggcccga tgaggattta tgaccaatgt   1860

tcagctatag aagctgataa ccacccagag caataacact tttattttaa acagagactt   1920

tttctcttaa tttctttctg ggtagtaaaa agaacatgtt tcattctttg cataaatact   1980

tgactctaag cattgacctt tgaaaacgct tgtattaaca atttttatta agaaagtgca   2040

ctctatataa catcttcttg cattacgata gctcattagc caatacacat gcagctatgt   2100

aagccacaac agcagacgtc ctatcctttt gcttttgttt ttaagggatc aaaatatttc   2160

aagggatacc atgaggaagg gtgtgagggg aaggggatat gccttggaca atgtcagagt   2220

tttgatttcc atgttttttc aagatccagg cttggtggtc gctatatttt tcagaaacag   2280

ataatgaaag actacattta atttaaaaag ttgggtgaaa caaccaaaag cagatgcaga   2340

gagagagagg gatgaatgcg ggggaagaat aaggggacgt gctggtgtcc gctggaaggg   2400

gcctctctgg gccccagagg acctgaggtt tgatggcagg aatctcccag acactcctgg   2460

cccccgcacc ccctgcagcc gcccgctctt ccctcccagc cctgccaggc aggcctggag   2520

gctgatacta aatcaaaacc ttaaagaggt gactggcagt ctggggaggg gagaagaggt   2580

ctgcaacgaa aatctaatta agaacattga gatgttcaca accaagttca gcttgcagct   2640

tccggggaaa tgcaaccgac ctctatgcca tctctagctg ggtaatcttc gaggccctga   2700

aatgcaattt tctgaacctc taagtcactt ttattttatg tcatgtgata aagacacaag   2760

tagtcacgca ctattggaaa taggttggga gggaggtctt taagatcgct tttaaaatag   2820

tttccaggac ttgtctaaaa atgatgacaa actttgaatc cagagggcct gttggtcaat   2880

gtgttggaaa ggacatttca ggccggcaga gtaattggat aattcacagg catagaggtg   2940

acttttggaa aattcattct cctatccatg ctgaaccagg cttccacgac tgggttctac   3000

ccaggccagt gggaagactc tgggaaactt caggccagcc ttgattggaa gaacttccag   3060

gaggagccat tgctgagatc caggctcact gtgattcact gaaaatgtag cgaaagggct   3120

gtcactggat attttgctat cccaaactct cagcctctgt gaataaagtt gttttttcat   3180

taacctctca aaaaaaaaaa aaaaaaa                                       3207


<210>  674
<211>  3057
<212>  DNA
<213>  Human

<400>  674
gaatcgagcg ccgagagagc gagtcggtgc tactggcgcc gggtcggtcc gggtaggcgc     60

agcgggactg gacctgggtg ccgagcggag ccgctgccat gggcctgggc gtcagcgctg    120

agcagcccgc aggcggcgcc gagggcttcc acctccacgg ggtgcaggag aactccccag    180

cccagcaggc gggcctggag ccctactttg acttcatcat caccattggg cactcgaggc    240

tgaacaagga gaatgacacc ctgaaggcac tactgaaagc caatgtggag aagcccgtga    300

agctggaggt gttcaatatg aagaccatga gggtgcgcga ggtggaggtg gtgcccagca    360

acatgtgggg cggccagggc ctactgggtg ccagtgtgcg cttctgcagc ttccgcaggg    420

ccagtgagca ggtgtggcat gtgctggatg tggaaccatc ttcacctgct gcccttgccg    480

gcctgcgccc ctacacagac tatgtggttg gttcggacca gattctccag gagtccgagg    540

acttctttac gctcatcgag tctcatgagg ggaagccctt gaagctgatg gtgtataact    600

ccaagtcaga ctcctgccgg gaggtgactg taactcccaa cgcagcctgg ggtggagagg    660

gcagtctggg atgtggcatt ggctatgggt atctacaccg gatcccaact cagcccccca    720

gctaccacaa gaagccacct ggcaccccac caccttctgc tctaccactt ggtgccccac    780

cacctgatgc tctaccacct ggacccaccc ccgaggactc tccttccctg gagacaggtt    840

ccaggcagag tgactacatg gaggccctgc tgcaggcacc tggctcctcc atggaggatc    900

cccttcctgg gcctgggagt cccagccaca gtgctccaga ccctgatgga cttccccatt    960

tcatggagac tcctcttcag cccccacctc cagtgcagcg agttatggac ccaggcttcc   1020

tggacgtgtc gggaatttct ctcttggaca acagcaatgc cagtgtgtgg cccagcctgc   1080

cctcttccac agaactgacc accacagctg tctcaacctc agggccagag gacatctgct   1140

ccagcagcag ttctcatgag cggggtggtg aggctacatg gtctgggtca gagtttgagg   1200

tctccttcct ggacagccca ggtgcccaag cccaggcgga ccacctgcct cagctgactc   1260

ttcctgacag tctcacctct gcagcctcac cagaagatgg gctgtccgcc gagctgcttg   1320

aagctcaggc tgaggaggaa ccagcaagca cagagggcct agatactggg acggaggctg   1380

aggggctgga cagccaggcc cagatctcta ccacagaata acaccctggg ctgtgacaag   1440

gcccatgatg acatttcatg aggcccagat gtgggcaggc agcccgggct gcactatgcg   1500

gtcaggattc cttgctgctt tggtgggaca tgaggcctca gtgggtggtg agagggggcc   1560

atgggccttg tgggaggata tcttttggcc gtgtaccctc aggtccagtg cttggtcctg   1620

ctctggtcac tggggcttcc caggaggcag cagggtctgg tcataatcca gtgtgaagat   1680

gaggtgagga aggaaggggt tgctgtccag tgttggcctg gtcgctttga ttcttcctgc   1740

acagctcagc ccaccccatc tgtactggaa gggaccctgg agccctggga ccaccccctt   1800

tcaagtccca aacactgagt cctctgtcat gtgtccttgt ccctaggcta caatgctaca   1860

cttggctcag gctgatcacc atgctagtca caggagggag agagaggcag tgtacttgcc   1920

cccatctcct ggagggaggt gcgttggaaa ttctaggccc ttcagcagag acccatttgt   1980

gcccagacca caatatttct tcttcctcag ggactacatg ccacagacct gtatccccag   2040

tggcaactcc tgttagctcc caaacttaaa cagtgatctc ttctaaatat acaaggcatc   2100

tacccagccc caatagtgaa taaaagtcac aaatttaagt tcaacaccct aagcaatttc   2160

tcaaagccag tctacctgac taggtctatc cacgcacggt tcccaacccc aagggggaat   2220

taggggatta gattaagagt aggtaaagac ccttttgttc tttcctgttg taggggagga   2280

agctgttctc cccaccccag gtgcctttgg aggttaaggc taggttaggc cctgcactcc   2340

acctggggac ggcccctcat cacctgaagt cctctgctgt gttgactgga ccctcagttc   2400

ccacactgct aattactatg aaagctgctc tggcctcgtc ttctagcttg tgcctagttg   2460

aaagtctcac ctttacagga tcatttgtaa tgctggtgta catgcaggga actcacaagc   2520

tgtgtcaggt atgcaggaca aggaatgtct gctctggggg gcacaggcca actatatgga   2580

gggagggtcc caaattagca aacccttcat ttaaagcaaa cccttgtcaa gcctaccaga   2640

gcagctgata cgtgtgcata acagtgaggc attgtgtcct ggatcgtctg ggagcccagt   2700

gtcaagtctg ctggaatgca ggaagtagaa cagaatcgcc acaggactgt tctggggcca   2760

gcttccctta actctgtagc ctggcagtct gacccaaagt tgccctcacc caaaggttct   2820

ggctcttccc tccctcactt ttactttccc ttcccccata agttggagga taaaatgggt   2880

atcaatgcta atatttccag ggagaacatg aaaccagagg tttctttctt tctctgtaat   2940

ctgctatgaa agaaaataac aaatgaaaat aaatgtgtac tacactttga aatattttaa   3000

ctaaagcctt tattctatac aactgtgaaa tacagatttt tacccttttg gcattgc      3057


<210>  675
<211>  2685
<212>  DNA
<213>  Human

<400>  675
tcccgcccgc gccctgccca ccccggccgc gcgcaccaca acgcccccgc cccgccgccc     60

ggaaccagct gagcgcagct ggacccagca gccgctgtct ccagtgccgc agcagcaggt    120

agtgctcata gctctctttg tccagtgctt cggccttggt cccagcgcct tcccacggag    180

cagcactctt caccctgcac agccttgtta gcccaacagc atggtggtgg aacaccccga    240

gttcctcaag gcagggaagg agcctggcct gcagatctgg cgtgtggaga agttcgatct    300

ggtgcccgtg cccaccaacc tttatggaga cttcttcacg ggcgacgcct acgtcatcct    360

gaagacagtg cagctgagga acggaaatct gcagtatgac ctccactact ggctgggcaa    420

tgagtgcagc caggatgaga gcggggcggc cgccatcttt accgtgcagc tggatgacta    480

cctgaacggc cgggccgtgc agcaccgtga ggtccagggc ttcgagtcgg ccaccttcct    540

aggctacttc aagtctggcc tgaagtacaa gaaaggaggt gtggcatcag gattcaagca    600

cgtggtaccc aacgaggtgg tggtgcagag actcttccag gtcaaagggc ggcgtgtggt    660

ccgtgccacc gaggtacctg tgtcctggga gagcttcaac aatggcgact gcttcatcct    720

ggacctgggc aacaacatcc accagtggtg tggttccaac agcaatcggt atgaaagact    780

gaaggccaca caggtgtcca agggcatccg ggacaacgag cggagtggcc gggcccgagt    840

gcacgtgtct gaggagggca ctgagcccga ggcgatgctc caggtgctgg gccccaagcc    900

ggctctgcct gcaggtaccg aggacaccgc caaggaggat gcggccaacc gcaagctggc    960

caagctctac aaggtctcca atggtgcagg gaccatgtcc gtctccctcg tggctgatga   1020

gaaccccttc gcccaggggg ccctgaagtc agaggactgc ttcatcctgg accacggcaa   1080

agatgggaaa atctttgtct ggaaaggcaa gcaggcaaac acggaggaga ggaaggctgc   1140

cctcaaaaca gcctctgact tcatcaccaa gatggactac cccaagcaga ctcaggtctc   1200

ggtccttcct gagggcggtg agaccccact gttcaagcag ttcttcaaga actggcggga   1260

cccagaccag acagatggcc tgggcttgtc ctacctttcc agccatatcg ccaacgtgga   1320

gcgggtgccc ttcgacgccg ccaccctgca cacctccact gccatggccg cccagcacgg   1380

catggatgac gatggcacag gccagaaaca gatctggaga atcgaaggtt ccaacaaggt   1440

gcccgtggac cctgccacat atggacagtt ctatggaggc gacagctaca tcattctgta   1500

caactaccgc catggtggcc gccaggggca gataatctat aactggcagg gtgcccagtc   1560

tacccaggat gaggtcgctg catctgccat cctgactgct cagctggatg aggagctggg   1620

aggtacccct gtccagagcc gtgtggtcca aggcaaggag cccgcccacc tcatgagcct   1680

gtttggtggg aagcccatga tcatctacaa gggcggcacc tcccgcgagg gcgggcagac   1740

agcccctgcc agcacccgcc tcttccaggt ccgcgccaac agcgctggag ccacccgggc   1800

tgttgaggta ttgcctaagg ctggtgcact gaactccaac gatgcctttg ttctgaaaac   1860

cccctcagcc gcctacctgt gggtgggtac aggagccagc gaggcagaga agacgggggc   1920

ccaggagctg ctcagggtgc tgcgggccca acctgtgcag gtggcagaag gcagcgagcc   1980

agatggcttc tgggaggccc tgggcgggaa ggctgcctac cgcacatccc cacggctgaa   2040

ggacaagaag atggatgccc atcctcctcg cctctttgcc tgctccaaca agattggacg   2100

ttttgtgatc gaagaggttc ctggtgagct catgcaggaa gacctggcaa cggatgacgt   2160

catgcttctg gacacctggg accaggtctt tgtctgggtt ggaaaggatt ctcaagaaga   2220

agaaaagaca gaagccttga cttctgctaa gcggtacatc gagacggacc cagccaatcg   2280

ggatcggcgg acgcccatca ccgtggtgaa gcaaggcttt gagcctccct cctttgtggg   2340

ctggttcctt ggctgggatg atgattactg gtctgtggac cccttggaca gggccatggc   2400

tgagctggct gcctgaggag gggcagggcc cacccatgtc accggtcagt gccttttgga   2460

actgtccttc cctcaaagag gccttagagc gagcagagca gctctgctat gagtgtgtgt   2520

gtgtgtgtgt gttgtttctt tttttttttt ttacagtatc caaaaatagc cctgcaaaaa   2580

ttcagagtcc ttgcaaaatt gtctaaaatg tcagtgtttg ggaaattaaa tccaataaaa   2640

acattttgaa gtgtgaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa                   2685


<210>  676
<211>  576
<212>  DNA
<213>  Human

<400>  676
actcttctgg tccccacaga ctcagagaga acccaccatg gtgctgtctc ctgccgacaa     60

gaccaacgtc aaggccgcct ggggtaaggt cggcgcgcac gctggcgagt atggtgcgga    120

ggccctggag aggatgttcc tgtccttccc caccaccaag acctacttcc cgcacttcga    180

cctgagccac ggctctgccc aggttaaggg ccacggcaag aaggtggccg acgcgctgac    240

caacgccgtg gcgcacgtgg acgacatgcc caacgcgctg tccgccctga gcgacctgca    300

cgcgcacaag cttcgggtgg acccggtcaa cttcaagctc ctaagccact gcctgctggt    360

gaccctggcc gcccacctcc ccgccgagtt cacccctgcg gtgcacgcct ccctggacaa    420

gttcctggct tctgtgagca ccgtgctgac ctccaaatac cgttaagctg gagcctcggt    480

ggccatgctt cttgcccctt gggcctcccc ccagcccctc ctccccttcc tgcacccgta    540

cccccgtggt ctttgaataa agtctgagtg ggcggc                              576


<210>  677
<211>  622
<212>  DNA
<213>  Human

<400>  677
cataaaccct ggcgcgctcg cgggccggca ctcttctggt ccccacagac tcagagagaa     60

cccaccatgg tgctgtctcc tgccgacaag accaacgtca aggccgcctg gggtaaggtc    120

ggcgcgcacg ctggcgagta tggtgcggag gccctggaga ggatgttcct gtccttcccc    180

accaccaaga cctacttccc gcacttcgac ctgagccacg gctctgccca ggttaagggc    240

cacggcaaga aggtggccga cgcgctgacc aacgccgtgg cgcacgtgga cgacatgccc    300

aacgcgctgt ccgccctgag cgacctgcac gcgcacaagc ttcgggtgga cccggtcaac    360

ttcaagctcc taagccactg cctgctggtg accctggccg cccacctccc cgccgagttc    420

acccctgcgg tgcacgcctc cctggacaag ttcctggctt ctgtgagcac cgtgctgacc    480

tccaaatacc gttaagctgg agcctcggta gccgttcctc ctgcccgctg ggcctcccaa    540

cgggccctcc tcccctcctt gcaccggccc ttcctggtct ttgaataaag tctgagtggg    600

cagcaaaaaa aaaaaaaaaa aa                                             622


<210>  678
<211>  1319
<212>  DNA
<213>  Human

<400>  678
cgcgcttggc cttgcccgcg cccgctcgcc tcgtctcgcc cggcctcccc gcgtcgcctc     60

gtcgcctgtt ccgcgccagg catggccccc agcactgtgg ccgtggagct gctcagcccc    120

aaagagaaaa accgactgcg gaagccggtg gtggagaaga tgcgccgcga ccgcatcaac    180

agcagcatcg agcagctgaa gctgctgctg gagcaggagt tcgcgcggca ccagcccaac    240

tccaagctgg agaaggccga catcctggag atggctgtca gctacctgaa gcacagcaaa    300

gccttcgtcg ccgccgccgg ccccaagagc ctgcaccagg actacagcga aggctactcg    360

tggtgcctgc aggaggccgt gcagttcctg acgctccacg ccgccagcga cacgcagatg    420

aagctgctgt accacttcca gcggcccccg gccgcgcccg ccgcgcccgc caaggagccc    480

aaggcgccgg gcgccgcgcc cccgcccgcg ctctccgcca aggccaccgc cgccgccgcc    540

gccgcgcacc agcccgcctg cggcctctgg cggccctggt gacccggcgg gacctgcggg    600

cgcgcggccc gacgaccaga gggcgagcct gctcctctcg cctgtaggga agcgccttcc    660

cgccgtcgtc cgccccgggc ttggacgcgc ccttctccgg aaggctctgg ccccaagctg    720

gccggcccgc aggagcccca ttctcagaga atgtgtgtgc agagtccctg ccgttttagg    780

acaatcaggg cccatcttct gccaagtgtc tgaccccatg gggttgttct gtgtttgcat    840

ttaagcaagt gacttctggg aagtccccgg ccgcccgggg ttctatgata tttgtagtgc    900

cggggctcgc acactgctgc ccccagcctg tagaggactt tcttcagggc ccgtagctgc    960

tgggcgtacc cctggcaggc gggctgtgcc gcgggcacat ttgccttttg tgaaggccga   1020

actcgagctg tatcctcata ggaaacagtg atcaccccgg acgggcgtcc aggaccctga   1080

gggccatggc caaaaggctc ctgagtgtgc ctggtggtct ggctggggct cacggtgggc   1140

tgtctgggga gggtgggtgc ctccactatg atccttaaag gattcctctg tgtgggtgga   1200

tgcgtgtggg cacgactttg tactcagaaa ttgaactctc agtcacgtgg aagccacggg   1260

actgctccga agccgccata ataaaatctg attgttcagc ccccaaaaaa aaaaaaaaa    1319


<210>  679
<211>  4622
<212>  DNA
<213>  Human

<400>  679
aatgagcgcg cgccgcgtcc ggggccggct ggtgcgcgag acgccgccga gaggttggtg     60

gctaatgtaa cagtttgcaa accgagagga gttgtgaagg gcgcgggtgg ggggcgctgc    120

cggcctcgtg ggtacgttcg tgccgcgtct gtcccagagc tggggccgca ggagcggagg    180

caagaggggc actatggcag acaaagttag gaggcagagg ccgaggaggc gagtctgttg    240

ggccttggtg gctgtgctct tggcagacct gttggcactg agtgatacac tggcagtgat    300

gtctgtggac ctgggcagtg agtccatgaa ggtggccatt gtcaaacctg gagtgcccat    360

ggaaattgtc ttgaataagg aatctcggag gaaaacaccg gtgatcgtga ccctgaaaga    420

aaatgaaaga ttctttggag acagtgcagc aagcatggcg attaagaatc caaaggctac    480

gctacgttac ttccagcacc tcctggggaa gcaggcagat aacccccatg tagctcttta    540

ccaggcccgc ttcccggagc acgagctgac tttcgaccca cagaggcaga ctgtgcactt    600

tcagatcagc tcgcagctgc agttctcacc tgaggaagtg ttgggcatgg ttctcaatta    660

ttctcgttct ctagctgaag attttgcaga gcagcccatc aaggatgcag tgatcaccgt    720

gccagtcttc ttcaaccagg ccgagcgccg agctgtgctg caggctgctc gtatggctgg    780

cctcaaagtg ctgcagctca tcaatgacaa caccgccact gccctcagct atggtgtctt    840

ccgccggaaa gatattaaca ccactgccca gaatatcatg ttctatgaca tgggctcagg    900

cagcaccgta tgcaccattg tgacctacca gatggtgaag actaaggaag ctgggatgca    960

gccacagctg cagatccggg gagtaggatt tgaccgtacc ctggggggcc tggagatgga   1020

gctccggctt cgagaacgcc tggctgggct tttcaatgag cagcgcaagg gtcagagagc   1080

aaaggatgtg cgggagaacc cgcgtgccat ggccaagctg ctgcgtgagg ctaatcggct   1140

caaaaccgtc ctcagtgcca acgctgacca catggcacag attgaaggcc tgatggatga   1200

tgtggacttc aaggcaaaag tgactcgtgt ggaatttgag gagttgtgtg cagacttgtt   1260

tgagcgggtg cctgggcctg tacagcaggc cctccagagt gccgaaatga gtctggatga   1320

gattgagcag gtgatcctgg tgggtggggc cactcgggtc cccagagttc aggaggtgct   1380

gctgaaggcc gtgggcaagg aggagctggg gaagaacatc aatgcagatg aagcagccgc   1440

catgggggca gtgtaccagg cagctgcgct cagcaaagcc tttaaagtga agccatttgt   1500

cgtccgagat gcagtggtct accccatcct ggtggagttc acgagggagg tggaggagga   1560

gcctgggatt cacagcctga agcacaataa acgggtactc ttctctcgga tggggcccta   1620

ccctcaacgc aaagtcatca cctttaaccg ctacagccat gatttcaact tccacatcaa   1680

ctacggcgac ctgggcttcc tggggcctga agatcttcgg gtatttggct cccagaatct   1740

gaccacagtg aagctaaaag gggtgggtga cagcttcaag aagtatcctg actacgagtc   1800

caagggcatc aaggctcact tcaacctgga tgagagtggc gtgctcagtc tagacagggt   1860

ggagtctgta tttgagacac tggtagagga cagcgcagaa gaggaatcta ctctcaccaa   1920

acttggcaac accatttcca gcctgtttgg aggcggtacc acaccagatg ccaaggagaa   1980

tggtactgat actgtccagg aggaagagga gagccctgca gaggggagca aggacgagcc   2040

tggggagcag gtggagctca aggaggaagc tgaggcccca gtggaggatg gctctcagcc   2100

cccaccccct gaacctaagg gagatgcaac ccctgaggga gaaaaggcca cagaaaaaga   2160

aaatggggac aagtctgagg cccagaaacc aagtgagaag gcagaggcag ggcctgaggg   2220

cgtcgctcca gccccagagg gagagaagaa gcagaagccc gccaggaagc ggcgaatggt   2280

agaggagatc ggggtggagc tggttgttct ggacctgcct gacttgccag aggataagct   2340

ggctcagtcg gtgcagaaac ttcaggactt gacactccga gacctggaga agcaggaacg   2400

ggaaaaagct gccaacagct tggaagcatt catatttgag acccaggaca agctgtacca   2460

gcccgagtac caggaagtgt ccacagagga gcagcgtgag gagatctctg ggaagctcag   2520

cgccgcatcc acctggctgg aggatgaggg tgttggagcc accacagtga tgttgaagga   2580

gaagctggct gagctgagga agctgtgcca agggctgttt tttcgggtag aggagcgcaa   2640

gaagtggccc gaacggctgt ctgccctcga taatctcctc aaccattcca gcatgttcct   2700

caagggggcc cggctcatcc cagagatgga ccagatcttc actgaggtgg agatgacaac   2760

gttagagaaa gtcatcaatg agacctgggc ctggaagaat gcaactctgg ccgagcaggc   2820

taagctgccc gccacagaga agcctgtgtt gctctcaaaa gacattgaag ctaagatgat   2880

ggccctggac cgagaggtgc agtatctgct caataaggcc aagtttacca agccccggcc   2940

ccggcctaag gacaagaatg ggacccgggc agagccaccc ctcaatgcca gtgccagtga   3000

ccagggggag aaggtcatcc ctccagcagg ccagactgaa gatgcagagc ccatttcaga   3060

acctgagaaa gtagagactg gatccgagcc aggagacact gagcctttgg agttaggagg   3120

tcctggagca gaacctgaac agaaagaaca atcgacagga cagaagcggc ctttgaagaa   3180

cgacgaacta taacccccac ctctgttttc cccattcatc tccaccccct tcccccacca   3240

cttctattta tttaacatcg agggttgggg gaggggttgg tcctgccctc ggctggagtt   3300

cctttctcac ccctgtgatt tggaggtgtg gagaagggga agggagggac agctcactgg   3360

ttccttctgc agtacctctg tggttaaaaa tggaaactgt tctcctcccc agccccactc   3420

cctgttccct acccatatag gccctaaatt tgggaaaaat cactattaat ttctgaatcc   3480

tttgcctgtg ggtaggaaga gaatggctgc cagtggctga tgggtcccgg tgatgggaag   3540

ggtatcaggt tgctggggag tttccactct tctctggtga ttgttccttc cctcccttcc   3600

tctcccacca tgcgatgagc atcctttcag gccagtgtct gcagagcctc agttaccagg   3660

tttggtttct gagtgcctat ctgtgctctt tcctccctct gcgggcttct cttgctctga   3720

gcctcccttc cccattcccc atccagctcc tttccccctg ggtttccttg gcttcctgca   3780

gcaaattggg cagttctctg ccccttgcct aaaagcctgt acctctggat tggcggaagt   3840

aaatctggaa ggattctcac tcgtatttcc cacccctagt ggccagagga gggaggggca   3900

cagtgaagaa gggagcccac cacctctccg aagaggaaag ccacgtagag tggttggcat   3960

ggggtgccag catcgtgcaa gctctgtcat aatctgcatc ttcccagcag cctggtaccc   4020

caggttcctg taactccctg cctcctcctc tcttctgctg ttctgctcct cccagacaga   4080

gcctttccct caccccctga ccccctgggc tgaccaaaat gtgctttcta ctgtgagtcc   4140

ctatcccaag atcctgggga aaggagagac catggtgtga atgtagagat gccacctccc   4200

tctctctgag gcaggcctgt ggatgaagga ggagggtcag ggctggcctt cctctgtgca   4260

tcactctgct aggttggggg cccccgaccc accataccta cgcctaggga gcccgtcctc   4320

cagtattccg tctgtagcag gagctagggc tgctgcctca gctccaagac aagaatgaac   4380

ctggctgtgt cagtcatttt gtcttttcct tttttttttt tttttgccac attggcagag   4440

atgggaccta agggtcccac ccctcacccc acccccacct cttctgtatg tttgaattct   4500

ttcagtagct gttgatgctg gttggacagg tttgagtcaa attgtacttt gctccattgt   4560

taattgagaa actgtttcaa taaaatattc ttttctacag ttaaaaaaaa aaaaaaaaaa   4620

aa                                                                  4622


<210>  680
<211>  1934
<212>  DNA
<213>  Human

<400>  680
gcaccgggtt ttattgggac acgccggcaa gacgcctctt cagttgtctg ctactcagag     60

gaaggggcgg ttggtgcggc ctccattgtt cgtgttttaa ggcgccatga ggggtgacag    120

aggccgtggt cgtggtgggc gctttggttc cagaggaggc ccaggaggag ggttcaggcc    180

ctttgtacca catatcccat ttgacttcta tttgtgtgaa atggcctttc cccgggtcaa    240

gccagcacct gatgaaactt ccttcagtga ggccttgctg aagaggaatc aggacctggc    300

tcccaattct gctgaacagg catctatcct ttctctggtg acaaaaataa acaatgtgat    360

tgataatctg attgtggctc cagggacatt tgaagtgcaa attgaagaag ttcgacaggt    420

gggatcctat aaaaagggga caatgactac aggacacaat gtggctgacc tggtggtgat    480

actcaagatt ctgccaacgt tggaagctgt tgctgccctg gggaacaaag tcgtggaaag    540

cctaagagca caggatcctt ctgaagtttt aaccatgctg accaacgaaa ctggctttga    600

aatcagttct tctgatgcta cagtgaagat tctcattaca acagtgccac ccaatcttcg    660

aaaactggat ccagaactcc atttggatat caaagtattg cagagtgcct tagcagccat    720

ccgacatgcc cgctggttcg aggaaaatgc ttctcagtcc acagttaaag ttctcatcag    780

actactgaag gacttgagga ttcgttttcc tggctttgag cccctcacac cctggatcct    840

tgacctacta ggccattatg ctgtgatgaa caaccccacc agacagcctt tggccctaaa    900

cgttgcatac aggcgctgct tgcagattct ggctgcagga ctgttcctgc caggttcagt    960

gggtatcact gacccctgtg agagtggcaa ctttagagta cacacagtca tgaccctaga   1020

acagcaggac atggtctgct atacagctca gactctcgtc cgaatcctct cacatggtgg   1080

ctttaggaag atccttggcc aggagggtga tgccagctat cttgcttctg aaatatctac   1140

ctgggatgga gtgatagtaa caccttcaga aaaggcttat gagaagccac cagagaagaa   1200

ggaaggagag gaagaagagg agaatacaga agaaccacct caaggagagg aagaagaaag   1260

catggaaact caggagtgac attcccttca ctccttttcc tacccaaggg ggaagactgg   1320

agcctaagct gcctgctact gggctttaca tggtgacaga catttccgtg ggatagggaa   1380

gatagcagga agaaaagtaa actccataga agtgtcattc cactgggttt tgatattggc   1440

ttagctgcca gtctcccatt tgtgacctat gccatccatc tataatggag gataccaaca   1500

tttcttccta atattctata atctccaact cctgaaaacc cctctctcaa ctaatacttt   1560

gctgttgaaa tgttgtgaaa tgttaagtgt ctggaaattt ttttttctaa gaaaaactat   1620

taaagtactt cctagtaggg ctcttggtct ttctggttgg tgttttttgt ttgtttgttt   1680

ttttgcatgt ggcaaccttt tttgcttttg gctttgtgta ctcttttgtt gaaaatgata   1740

attgagtcat ttaattataa atactcagat cacaatttga agctgtcttt gaattaaagg   1800

acaaactcct ggaacctttc catataccag agtaaactag aatatcattt taagtattta   1860

ttgaataaaa tgattctatc aacactgaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1920

aaaaaaaaaa aaaa                                                     1934


<210>  681
<211>  6704
<212>  DNA
<213>  Human

<400>  681
ggcaacatgc cagccccgta gcactgccca ccccacccac tgtggtctgt tgtaccccac     60

tgctggggtg gtggttccaa tgagacaggg cacaccaaac tccatctggc tgttactgag    120

gcggagacac gggtgatgat tggctttctg gggagagagg aagtcctgtg attggccaga    180

tctctggagc ttgccgacgc ggtgtgagga cgctcccacg gaggccggaa ttggctgtga    240

aaggactgag gcagccatct gggggtagcg ggcactctta tcagagcggc tggagccgga    300

ccatcgtccc agagagctgg ggcagggggc cgtgcccaat ctccagggct cctggggcca    360

ctgctgacct ggctggatgc atcgggcagt ggaccctcca ggggcccgcg ctgcacggga    420

agcctttgcc cttgggggcc tgagctgtgc tggggcctgg agctcctgcc cgcctcatcc    480

ccctcctcgt agcgcatggc tgcctggagg cagatgctca gccagcattg ggcagccccc    540

gcttcctgct cccctacccc cttcacatgg cagtagttct gggcacccca gcaaaccata    600

ttatgctcca ggggcgccca ctccaagacc cctccatggg aagctggaat ccctgcatgg    660

ctgtgtgcag gcattgctcc gggagccagc ccagccaggg ctttgggaac agcttgggca    720

actgtacgag tcagagcacg atagtgagga ggccacacgc tgctaccaca gcgcccttcg    780

atacggagga agcttcgctg agctggggcc ccgcattggc cgactgcagc aggcccagct    840

ctggaacttt catactggct cctgccagca ccgagccaag gtcctgcccc cactggagca    900

agtgtggaac ttgctacacc ttgagcacaa acggaactat ggagccaagc ggggaggtcc    960

cccggtgaag cgagctgctg aacccccagt ggtgcagcct gtgcctcctg cagcactctc   1020

aggcccctca ggggaggagg gcctcagccc tggaggcaag cgaaggagag gctgcaactc   1080

tgaacagact ggccttcccc cagggctgcc actgcctcca ccaccattac caccaccacc   1140

accaccacca ccaccaccac caccacccct gcctggcctg gctaccagcc ccccatttca   1200

gctaaccaag ccagggctgt ggagtaccct gcatggagat gcctggggcc cagagcgcaa   1260

gggttcagca cccccagagc gccaggagca gcggcactcg ctgcctcacc catatccata   1320

cccagctcca gcgtacaccg cgcacccccc tggccaccgg ctggtcccgg ctgctccccc   1380

aggcccaggc ccccgccccc caggagcaga gagccatggc tgcctgcctg ccacccgtcc   1440

ccccggaagt gaccttagag agagcagagt tcagaggtcg cggatggact ccagcgtttc   1500

accagcagca accaccgcct gcgtgcctta cgccccttcc cggccccctg gcctccccgg   1560

caccaccacc agcagcagca gtagcagcag cagcaacact ggtctccggg gcgtggagcc   1620

gaacccaggc attcccggcg ctgaccatta ccaaactccc gcgctggagg tctctcacca   1680

tggccgcctg gggccctcgg cacacagcag tcggaaaccg ttcttggggg ctcccgctgc   1740

cactccccac ctatccctgc cacctggacc ttcctcaccc cctccacccc cctgtccccg   1800

cctcttacgc cccccaccac cccctgcctg gttgaagggt ccggcctgcc gggcagcccg   1860

agaggatgga gagatcttag aagagctctt ctttgggact gagggacccc cccgccctgc   1920

cccaccaccc ctcccccatc gcgagggctt cttggggcct ccggcctccc gcttttctgt   1980

gggcactcag gattctcaca cccctcccac tcccccaacc ccaaccacca gcagtagcaa   2040

cagcaacagt ggcagccaca gcagcagccc tgctgggcct gtgtcctttc ccccaccacc   2100

ctatctggcc agaagtatag acccccttcc ccggcctccc agcccagcac agaaccccca   2160

ggacccacct cttgtacccc tgactcttgc cctgcctcca gcccctcctt cctcctgcca   2220

ccaaaatacc tcaggaagct tcaggcgccc ggagagcccc cggcccaggg tctccttccc   2280

aaagaccccc gaggtggggc cggggccacc cccaggcccc ctgagtaaag ccccccagcc   2340

tgtgccgccc ggggttgggg agctgcctgc ccgaggccct cgactctttg attttccccc   2400

cactccgctg gaggaccagt ttgaggagcc agccgaattc aagatcctac ctgatgggct   2460

ggccaacatc atgaagatgc tggacgaatc cattcgcaag gaagaggaac agcaacaaca   2520

cgaagcaggc gtggcccccc aacccccgct gaaggagccc tttgcatctc tgcagtctcc   2580

tttccccacc gacacagccc ccaccactac tgctcctgct gtcgccgtca ccaccaccac   2640

caccaccacc accaccacca cggccaccca ggaagaggag aagaagccac caccagccct   2700

accaccacca ccgcctctag ccaagttccc tccaccctct cagccacagc caccaccacc   2760

cccacccccc agcccggcca gcctgctcaa atccttggcc tccgtgctgg agggacaaaa   2820

gtactgttat cgggggactg gagcagctgt ttccacccgg cctgggccct tgcccaccac   2880

tcagtattcc cctggccccc catcaggtgc taccgccctg ccgcccacct cagcggcccc   2940

tagcgcccag ggctccccac agccctctgc ttcctcgtca tctcagttct ctacctcagg   3000

cgggccctgg gcccgggagc gcagggcggg cgaagagcca gtcccgggcc ccatgacccc   3060

cacccaaccg cccccacccc tatctctgcc ccctgctcgc tctgagtctg aggtgctaga   3120

agagatcagc cgggcttgcg agacccttgt ggagcgggtg ggccggagtg ccactgaccc   3180

agccgaccca gtggacacag cagagccagc ggacagtggg actgagcgac tgctgccccc   3240

cgcacaggcc aaggaggagg ctggcggggt ggcggcagtg tcaggcagct gtaagcggcg   3300

acagaaggag catcagaagg agcatcggcg gcacaggcgg gcctgtaagg acagtgtggg   3360

tcgtcggccc cgtgagggca gggcaaaggc caaggccaag gtccccaaag aaaagagccg   3420

ccgggtgctg gggaacctgg acctgcagag cgaggagatc cagggtcgtg agaagtcccg   3480

gcccgatctt ggcggggcct ccaaggccaa gccacccaca gctccagccc ctccatcagc   3540

tcctgcacct tctgcccagc ccacaccccc gtcagcctct gtccctggaa agaaggctcg   3600

ggaggaagcc ccagggccac cgggtgtcag ccgggccgac atgctgaagc tgcgctcact   3660

tagtgagggg ccccccaagg agctgaagat ccggctcatc aaggtagaga gtggtgacaa   3720

ggagaccttt atcgcctctg aggtggaaga gcggcggctg cgcatggcag acctcaccat   3780

cagccactgt gctgctgacg tcgtgcgcgc cagcaggaat gccaaggtga aagggaagtt   3840

tcgagagtcc tacctttccc ctgcccagtc tgtgaaaccg aagatcaaca ctgaggagaa   3900

gctgccccgg gaaaaactca acccccctac acccagcatc tatctggaga gcaaacggga   3960

tgccttctca cctgtcctgc tgcagttctg tacagaccct cgaaatccca tcacagtgat   4020

ccggggcctg gcgggctccc tgcggctcaa cttgggcctc ttctccacca agaccctggt   4080

ggaagcgagt ggcgaacaca ccgtggaagt tcgcacccag gtgcagcagc cctcagatga   4140

gaactgggat ctgacaggca ctcggcagat ctggccttgt gagagctccc gttcccacac   4200

caccattgcc aagtacgcac agtaccaggc ctcatccttc caggagtctc tgcaggagga   4260

gaaggagagt gaggatgagg agtcagagga gccagacagc accactggaa cccctcctag   4320

cagcgcacca gacccgaaga accatcacat catcaagttt ggcaccaaca tcgacttgtc   4380

tgatgctaag cggtggaagc cccagctgca ggagctgctg aagctgcccg ccttcatgcg   4440

ggtaacatcc acgggcaaca tgctgagcca cgtgggccac accatcctgg gcatgaacac   4500

ggtgcagctg tacatgaagg tgcccggcag ccgaacgcca ggccaccagg agaataacaa   4560

cttctgctcc gtcaacatca acattggccc aggcgactgc gagtggttcg cggtgcacga   4620

gcactactgg gagaccatca gcgctttctg tgatcggcac ggcgtggact acttgacggg   4680

ttcctggtgg ccaatcctgg atgatctcta tgcatccaat attcctgtgt accgcttcgt   4740

gcagcgaccc ggagacctcg tgtggattaa tgcggggact gtgcactggg tgcaggccac   4800

cggctggtgc aacaacattg cctggaacgt ggggcccctc accgcctatc agtaccagct   4860

ggccctggaa cgatacgagt ggaatgaggt gaagaacgtc aaatccatcg tgcccatgat   4920

tcacgtgtca tggaacgtgg ctcgcacggt caaaatcagc gaccccgact tgttcaagat   4980

gatcaagttc tgcctgctgc agtccatgaa gcactgccag gtgcaacgcg agagcctggt   5040

gcgggcaggg aagaaaatcg cttaccaggg ccgtgtcaag gacgagccag cctactactg   5100

caacgagtgc gatgtggagg tgtttaacat cctgttcgtg acaagtgaga atggcagccg   5160

caacacgtac ctggtacact gcgagggctg tgcccggcgc cgcagcgcag gcctgcaggg   5220

cgtggtggtg ctggagcagt accgcactga ggagctggct caggcctacg acgccttcac   5280

gctggtgagg gcccggcggg cgcgcgggca gcggaggagg gcactggggc aggctgcagg   5340

gacgggcttc gggagcccgg ccgcgccttt ccctgagccc ccgccggctt tctcccccca   5400

ggccccagcc agcacgtcgc gatgaggccg gacgccccgc ccgcctgcct gcccgcgcaa   5460

ggcgccgcgg ggccaccagc acatgcctgg gctggaccta ggtcccgcct gtggccgaga   5520

agggggtcgg gcccagccct tccaccccat tggcagctcc cctcacttaa tttattaaga   5580

aaaacttttt tttttttttt agcaaatatg aggaaaaaag gaaaaaaaat gggagacggg   5640

ggagggggct ggcagcccct cgcccaccag cgcctcccct caccgacttt ggccttttta   5700

gcaacagaca caaggaccag gctccggcgg cggcgggggt cacatacggg ttccctcacc   5760

ctgccagccg cccgcccgcc cggcgcagat gcacgcggct cgtgtatgta catagacgtt   5820

acggcagccg aggtttttaa tgagattctt tctatgggct ttacccctcc cccggaacct   5880

ccttttttac ttccaatgct agctgtgacc cctgtacatg tctctttatt cacttggtta   5940

tgatttgtat tttttgttct tttcttgttt ttttgttttt aatttataac agtcccactc   6000

acctctattt attcattttt gggaaaaccc gacctcccac acccccaagc catcctgccc   6060

gcccctccag ggaccgcccg tcgccgggct ctccccgcgc cccagtgtgt gtccgggccc   6120

ggcccgaccg tctccacccg tccgcccgcg gctccagccg ggttctcatg gtgctcaaac   6180

ccgctcccct cccctacgtc ctgcactttc tcggaccagt ccccccactc ccgacccgac   6240

cccagcccca cctgagggtg agcaactcct gtactgtagg ggaagaagtg ggaactgaaa   6300

tggtattttg taaaaaaaat aaataaaata aaaaaattaa aggttttaaa gaaagaacta   6360

tgaggaaaag gaaccccgtc cttcccagcc ccggccaact ttaaaaaaca cagaccttca   6420

cccccacccc cttttctttt taagtgtgaa acaacccagg gccagggcct cactggggca   6480

gggacacccc ggggtgagtt tctctggggc tttattttcg ttttgttggt tgttttttct   6540

ccacgctggg gctgcggagg ggtggggggt ttacagtccc gcaccctcgc actgcactgt   6600

ctctctgccc caggggcaga ggggtcttcc caaccctacc cctattttcg gtgatttttg   6660

tgtgagaata ttaatattaa aaataaacgg agaaaaaaaa tcct                    6704


<210>  682
<211>  7773
<212>  DNA
<213>  Human

<400>  682
agagcctcgg tggtttgcag cagtggaacc aggcaggccc agttgtgggt aggagaggcc     60

gtcacctgtt gaggcctccc ccccacaccc ccgcatcgcc ctgccctggc agagcccagc    120

ccccagtccc cggagagcgc gcctgaggac ggacggacgg acggacggac agacctaggg    180

acggagggcc aggggcaggg gagatccaag aggccccgcg ctggaatgca gttttctcgg    240

gcgagggaga ctttgcaccg gagtggaaaa tagtttgggg tggggtttcg caccgtcccc    300

tcctccccag ccccgggccc cctcccaggc gctttctggg agcttttaga actgcgctct    360

gaagtttcca gagagcgagg agcttttgcg gcaggcagag acaatggaag aaaatgaaag    420

ccagaaatgt gagccgtgcc ttccttactc agcagacaga agacagatgc aggaacaagg    480

caaaggcaat ctgcatgtaa catcaccaga agatgcagaa tgccgcagaa ccaaggaacg    540

cctttctaat ggaaacagtc gtggttcagt ttccaagtct tcccgcaata tcccaaggag    600

acacacccta ggggggcccc gaagttccaa ggaaatactg ggaatgcaaa catctgagat    660

ggatcggaag agagaagcgt tcctagaaca tctgaagcag aagtaccccc accacgcctc    720

tgcaatcatg ggtcaccaag agaggctgag agaccagaca aggagcccca aactgtctca    780

cagtcctcaa ccacccagtc tgggtgaccc ggtcgagcat ttatcagaga cgtccgctga    840

ttctttggaa gccatgtctg agggggatgc tccaacccct ttttccagag gcagccggac    900

tcgtgcgagc cttcctgtgg tgaggtcaac caaccagacg aaagaaagat ctctgggggt    960

tctctatctc cagtatggag atgaaaccaa gcagctcagg atgccgaatg aaatcacaag   1020

tgcagacaca atccgtgctc tcttcgtaag tgcctttcca cagcagctca ccatgaaaat   1080

gctggaatcg cccagtgtcg ccatttacat caaagatgaa agcagaaatg tctattatga   1140

attaaatgat gtaaggaaca ttcaagacag atcactcctc aaagtgtaca acaaggatcc   1200

tgcacatgcg tttaatcaca caccaaaaac tatgaatgga gacatgagga tgcagagaga   1260

acttgtttat gcaagaggag atggccctgg ggcccctcgc cccggatcta ctgctcatcc   1320

accccatgcg attccaaatt ccccaccgtc tactccagtg ccccattcca tgcccccctc   1380

cccgtccaga attccttatg ggggcacccg ctccatggtt gttcctggca atgccaccat   1440

ccccagggac agaatctcca gcctgccagt ctccagaccc atctctccaa gcccaagcgc   1500

cattttagaa agaagagatg tcaagcctga tgaagacatg agtggcaaaa acattgcaat   1560

gtacagaaat gagggtttct atgctgatcc ttacctttat cacgagggac ggatgagcat   1620

agcctcatcc catggtggac acccactgga tgtccccgac cacatcattg catatcaccg   1680

caccgccatc cggtcagcga gtgcttattg taacccctca atgcaagcgg aaatgcatat   1740

ggaacaatca ctgtacagac agaaatcaag gaaatatccg gatagccatt tgcctacact   1800

gggctccaaa acaccccctg cctctcctca cagagtcagt gacctgagga tgatagacat   1860

gcacgctcac tataatgccc acggcccccc tcacaccatg cagccagacc gggcctctcc   1920

gagccgccag gcctttaaaa aggagccagg caccttggtg tatatagaaa agccacggag   1980

cgctgcagga ttatccagcc ttgtagacct cggccctcct ctaatggaga agcaagtttt   2040

tgcctacagc acggcgacaa tacccaaaga cagagagacc agagagagga tgcaagccat   2100

ggagaaacag attgccagtt taactggcct tgttcagtct gcgcttttta aagggcccat   2160

tacaagttat agcaaagatg cgtctagcga gaaaatgatg aaaaccacag ccaacaggaa   2220

ccacacagat agtgcaggaa cgccccatgt gtctggtggg aagatgctca gtgctctgga   2280

gtccacggtg cctcccagcc agcctccacc tgtgggcacc tcagccatcc acatgagcct   2340

gcttgagatg aggcggagcg tggcggaact caggctccag ctccagcaga tgcggcagct   2400

ccagctgcag aaccaggagt tgctgagggc aatgatgaag aaggccgagc tggaaatcag   2460

tggcaaagtg atggaaacaa tgaagagact ggaggatccc gtgcagcgac agcgcgtcct   2520

agtggagcaa gagagacaaa aatatcttca tgaggaagag aagatcgtca agaagttgtg   2580

cgagttggaa gactttgttg aagacttgaa gaaggactcc acggcagcca gccgattggt   2640

tactctgaaa gacgtggaag acggggcttt cctcctgcgt caagtgggag aggctgtagc   2700

taccctgaaa ggagaatttc caaccttaca aaacaagatg cgagccatcc tgcgcataga   2760

agtggaggcc gtgcggtttc tgaaggagga gccacacaag ctggacagtc tcctgaagcg   2820

tgtgcgcagc atgacagacg tcctgaccat gctgcggaga catgtcactg atgggctcct   2880

gaaaggcacg gacgcagccc aagccgcaca gtacatggct atggaaaagg ccacagccgc   2940

agaagtcctg aagagtcagg aggaggcagc ccacacctcc ggccagccct tccacagcac   3000

aggtgcccct ggcgatgcga agtcggaagt ggtgcctttg tccggcatga tggttcgcca   3060

cgcgcagagc tcccctgtgg tcatccagcc ctcccagcac tccgtggccc tgctgaaccc   3120

tgctcagaac ttgcctcacg tggccagctc cccagccgtc ccccaggaag caacctccac   3180

tctgcagatg tcgcaggctc cgcagtcccc acagataccc atgaatgggt ctgccatgca   3240

gagcttgttc attgaagaaa tccacagtgt gagtgccaag aacagggcag tgtctatcga   3300

gaaagcagaa aagaaatggg aggaaaaaag gcaaaatctg gatcactata atgggaaaga   3360

gtttgagaag ctcctagaag aagctcaggc caatatcatg aagtcaatac caaatctgga   3420

gatgccgcca gccacaggcc cactgccaag gggagatgcc ccagtggaca aggtggaact   3480

ttcagaagat tctccaaatt cggaacagga cttggaaaag ctggggggaa agtcgccccc   3540

tcctcctccg ccacctcctc gtcgaagcta cctgccagga tcgggactca ccaccacgag   3600

gtcaggcgat gtggtctaca ccggcagaaa ggagaacatc accgctaagg caagcagtga   3660

agatgctgga ccaagcccac agaccagagc tacaaaatat ccagcagagg agcctgcttc   3720

agcctggacc ccatccccac cgcctgtcac cacctcctcc tcaaaggatg aggaggaaga   3780

agaagaagaa ggagacaaaa taatggcaga actccaggca ttccagaagt gttcctttat   3840

ggatgtaaat tcaaacagtc atgctgagcc atcccgggct gacagtcacg ttaaagacac   3900

taggtcgggc gccacagtgc cacccaagga gaagaagaat ttggaatttt tccatgaaga   3960

tgtacggaaa tctgatgttg aatatgaaaa tggcccccaa atggaattcc aaaaggttac   4020

cacaggggct gtaagaccta gtgaccctcc taagtgggaa agaggaatgg agaatagtat   4080

ttctgatgca tcaagaacat cagaatataa aactgagatc ataatgaagg aaaattccat   4140

atccaatatg agtttactca gagacagtag aaactattcc caggaaactg tgcctaaggc   4200

cagtttcggt ttctctggca ttagtccatt agaagatgaa ataaacaaag ggtctaaaat   4260

ctcaggcctg caatactcta tacctgacac cgagaaccag acgctgaatt acggaaagac   4320

aaaggagatg gaaaagcaaa atacggataa gtgtcacgtt tcctctcaca ctagactaac   4380

agaatcaagc gtgcatgatt ttaaaacaga agatcaagag gttatcacga cagattttgg   4440

ccaagttgtt ctaagaccca aggaggcaag gcatgctaac gtgaacccta atgaggatgg   4500

agaatcaagt tcaagttctc ccactgaaga aaatgcagcc actgacaata ttgccttcat   4560

gattaccgaa accactgtcc aggttctttc cagtggggag gtgcatgata ttgttagcca   4620

aaagggagaa gacatacaga cggttaatat cgatgccaga aaagagatga ccccccgaca   4680

agaagggact gacaatgagg atccagtcgt gtgcctggac aagaaaccag tgatcatcat   4740

tttcgatgag cccatggaca tccggtctgc ctataagaga ctttcaacta tctttgagga   4800

atgtgatgag gaattagaga gaatgatgat ggaggaaaag atagaggagg aggaagagga   4860

ggaaaatggg gattctgtag tccagaataa taacacttcc cagatgtctc ataagaaggt   4920

ggccccaggc aatcttagaa ccggacaaca ggtggaaaca aagtcacagc cacactccct   4980

ggccacagag accagaaacc caggaggaca ggaaatgaac agaacggagc tgaacaagtt   5040

cagccacgtg gattctccaa attcggaatg caagggtgag gacgcgaccg atgaccagtt   5100

tgaaagcccc aagaaaaagt ttaaattcaa attccctaag aagcaactcg ccgctctcac   5160

tcaagccatt cgcaccggaa ctaaaacagg gaagaagact ttgcaagtgg tagtctatga   5220

agaagaggaa gaggatggca ccctgaaaca gcacaaagaa gccaagcgct tcgaaatcgc   5280

taggtctcaa cctgaagaca cccctgaaaa cacagtgagg aggcaagagc agcccagcat   5340

cgagagtaca tctccgattt caagaactga tgaaattaga aaaaacacct acagaacatt   5400

ggatagcctg gagcagacca ttaaacagct cgaaaataca atcagtgaaa tgagtcccaa   5460

agccctagtt gatacctcat gttcttccaa cagagattct gttgcaagtt catcccacat   5520

agcccaagag gcctctcccc gacccttgct agttccggat gaaggtccca ctgccctaga   5580

gccccctacg tcgatacctt cagcttcacg taagggctcc agcggggccc cacagacgag   5640

caggatgcct gtccccatga gtgccaagaa cagacccgga accctggaca aacccggcaa   5700

gcagtccaaa ctgcaggatc cccgccaata tcgtcaggct aatggaagtg ctaagaaatc   5760

tggtggggac tttaagccta cttccccctc cttacctgct tctaagattc cagccctttc   5820

tcccagctct gggaaaagca gttctctgcc ctcttctagt ggtgacagct ctaacctccc   5880

taatccacct gctactaaac catcgattgc ttctaaccct ctcagccccc aaacaggacc   5940

acctgctcac tctgcctccc tcatcccttc tgtctctaat ggctctttga agtttcagag   6000

cctcactcat acaggtaaag gtcaccatct ttcattctca ccgcagagtc aaaatggccg   6060

agcaccccct cctttgtcat tttcctcctc ccctccttct cctgcctcct ccgtctcact   6120

gaatcaaggt gccaagggca ccaggaccat ccatactccc agcctcacca gctacaaggc   6180

acagaatgga agttcaagca aagccacccc atccacagca aaagaaacct cttaaaggtc   6240

aaatcctatt aggcacaagt cggagttaca tttaaaaaaa attaacagtc tacaacaact   6300

gttttcacaa gagaatgtaa catattgctg tatcgtttga ggcttaatgc taaatatgtg   6360

ctaaatactg gattaataga tttcagtaaa gctcgttcgt tttgtttggt tttcttttta   6420

cctagttgct atagtgtcta cagtctatac tcaataccta taaaatgcag taagcatgtg   6480

ttacagaaag aggttctggt gggagagaaa ggtgcgtgtg agacaggaga attgtcttaa   6540

gcatataaaa catgtatgat tccagaattt tagtatgttt tgtataaaac tatttttcat   6600

tacggagact agaagtgaac agagaattac acaagtgtga ctatacaaat tgtaaaacag   6660

atactataat atttcctttt attttagtgt tatttagctt tattacagat ttctattttt   6720

gtcaaaactt catggttcct ttcaagatct tttttgccaa aacattttga tactatagca   6780

ttgtacattt gaaagtagtg ttctagacta taaaaccaat gaacttctac atgagcccta   6840

cagacaggca tgtgtagaag gcaatttatc aaacctattg cactgccatg aaaagtgtgt   6900

ataataattt gctagcccaa gcaagctagt tttctttgct tgcttctttt ctttcttttt   6960

tccttccttt tttttttttt tttctttttt aacatgttga gattctctag ttgttttctt   7020

tggcgtatct aaccccttct tttgttttct gagacctggt aacccacgct cttgcattgt   7080

ggattttaaa atgtatactc tgtacggttc tgtaaaccga aaaacttttg taaatatata   7140

aatatacata gacataaaaa tactgtatgt gacagcacat agagtagttt tcccacacca   7200

aagttaattt ttatgcatgc tttaaaagta tatatcggga ccggcagaaa tggaagtatc   7260

catacatttt taaaaagcaa caagtttgca cagctagagt gtttttgtaa ataaatgtat   7320

ttgtataaca cagtcatgta atatacagaa ctataagcag agactttgca aaactaaata   7380

aagggctgca tgcttattat tttttgtacc ttgtcactat aactacttcc tagtcaaaga   7440

acgaaatgta actgttaccg agttaaatgt ttttccgctt tgagggatgt aaccacatcc   7500

actcagagga cactactttt ctgaaagctc tggggtgact aatgatgagt tcctaataaa   7560

ttaattgcaa gtgtggtgcc ttggatgtgg cctgttggct cgctttcttc tctgtggctt   7620

atcaaggtgt agatgacaga aagcaaacct ggatacagag tttccaccct cagttcctgg   7680

aggggctctt attattttct ctctttttaa aaaacttcca gtagaagtaa agtggaaata   7740

aaatgtcttt atcaaaaaaa aaaaaaaaaa aaa                                7773


<210>  683
<211>  4120
<212>  DNA
<213>  Human

<400>  683
gcggcggtag cagcagcggg cccggctggg gcgcgagcgc ggcgcagccc agcccagccc     60

agtccgagcg cggacccggc gcccgcagcc ccggcgccgc catggtggag gcggcgcccc    120

ccgggcccgg gccgctgcgg aggacctttc tagtgcccga gatcaagtcg ctggaccagt    180

acgatttctc gcgggccaag gcggcggcca gcctggcgtg ggtgctgcgg gccgcgttcg    240

ggggcgcaga gcacgtgccc ccggagctgt gggagccctt ctataccgac cagtacgcgc    300

aggagcatgt gaagcccccg gtgacacggc tgctgctctc agccgagctc tactgcagag    360

cctggcgcca ggcactgcca cagcttgaaa caccccccaa cccctctgca ctgctggccc    420

tgctggcgcg gaggggcaca gtgcctgctt tgcccgagcg cccggtgcgc gaggccgacc    480

tgaggcacca gcccattctc atgggagccc acctagctgt cattgatgcc ctcatggctg    540

cctttgcctt cgagtggaca aagaccctgc caggtccctt ggccctgacc agcttggagc    600

acaagctgct tttctgggtg gacacgaccg tccggcggct gcaggagaag accgagcagg    660

aagcggccca gcgagcctct ccagcagccc ctgcagacgg ggcggccccg gcgcagccct    720

cgatccgata ccgcaaggac cgtgtggtgg cgcgacgtgc cccctgcttc ccgacggtga    780

ccagcctcca ggacctggcc agtggggccg cgctggccgc caccatccac tgctattgtc    840

cccagctgct tcgacttgag gaggtgtgct tgaaggaccc catgtctgtg gcggacagcc    900

tgtacaacct ccagctcgtg caggatttct gtgcctctcg ccttcctcgt ggctgccccc    960

tgtcccttga ggacttgctg tacgtcccac cgccactcaa ggtcaacttg gtggtgatgc   1020

tggccgagtt gttcatgtgt tttgaggtgc tcaagcccga ctttgtgcaa gtgaaggact   1080

tgcccgatgg tcacgctgcc tccccccggg gcactgaggc ctccccacct cagaacaaca   1140

gcggcagtag ttctcctgtc ttcaccttcc gccacccgct tctgtcatct ggtggccccc   1200

agtccccact ccgaggatcc acaggctccc tgaagtcttc cccgtccatg tcccatatgg   1260

aggccctggg caaggcctgg aaccggcagc tcagccgtcc cctctcccag gctgtgtcat   1320

tcagcacccc ctttggcctg gacagcgacg tggatgtcgt catgggagac cctgtgctcc   1380

tccgctctgt gagctcggac agcctgggcc ccccgcgtcc cgcgccggcc aggaccccca   1440

cccagccacc cccggagcct ggtgacctgc ccaccatcga ggaagctctg cagatcatcc   1500

acagtgccga gccccggctc ctcccagatg gggcggccga cggcagcttc tacctccact   1560

cccctgaggg gccctccaag ccatccctgg cctcccccta cctgcccgag gggacctcca   1620

aaccactgtc cgacaggccc accaaagcac cagtgtacat gccacacccc gagaccccct   1680

cgaaaccatc tccctgtctg gtgggggagg catcgaaacc gccagcccca tccgaggggt   1740

ccccgaaggc ggtggcttcg tccccagcag ccaccaactc cgaggtgaaa atgaccagct   1800

ttgcagaacg caagaaacag ctggtgaagg cagaggctga ggccggagcg gggtccccca   1860

cgtccactcc ggccccgccg gaggccctga gctcggagat gagtgagctc agcgcccggc   1920

tggaggagaa acgcagagcc atcgaggctc agaagcgacg gattgaggcc atattcgcca   1980

agcaccgcca gcggctgggc aaaagcgcct tcctgcaggt gcagccgcgg gaagcctctg   2040

gggaggcgga agcagaggcg gaggaggccg attccggtcc agtccctggt ggggagcggc   2100

ccgcaggcga gggccagggt gagccaacct cacggcccaa ggcagtgacc ttctcgccag   2160

acctgggccc ggtgccccac gaggggctgg gggaatacaa tcgagcggtc agcaagctga   2220

gtgccgcctt gagctcgctg cagcgggaca tgcagaggct cacggaccag cagcagcggc   2280

tcctggcccc gcccgaggcc cccggatccg ccccaccacc tgctgcgtgg gtcatccctg   2340

gccccacgac ggggcccaaa gctgcatccc ccagccccgc ccggcgagtc ccggccaccc   2400

ggcgcagccc tgggcccggg cccagccagt caccccgcag cccgaaacac acgcggccag   2460

cggagctgcg gctggcaccc ttgaccaggg tgcttacgcc accccacgac gtagacagcc   2520

tcccccacct gcgcaagttc tcgccgagcc aggtgcccgt gcagacgcgc tcttccatcc   2580

tcctggcgga ggagacgccc cccgaggagc cagccgcccg gccgggcctc atcgagatcc   2640

cgctgggcag cctggcagat cccgccgccg aggacgaggg agacgggagc cccgctggtg   2700

ctgaggattc cttggaggag gaggcgtctt cggaggggga gccccgggtg gggctggggt   2760

tcttctacaa ggatgaagac aagcctgagg acgagatggc ccaaaagcgg gccagcctgc   2820

tggagcggca gcagcggcga gcagaggagg cgcggcggcg caagcagtgg caggaggtgg   2880

agaaggaaca gcggagggag gaggccgcga ggctggccca agaggaggcc ccgggcccag   2940

ccccgcttgt gtccgcagtc ccgatggcga ctccagcccc tgctgcccgg gctccagccg   3000

aggaggaggt gggcccccgg aagggggact tcacgcggca ggagtacgag cgccgggccc   3060

agctgaagct gatggacgac ctcgataagg tgctgcggcc ccgggctgcg gggtccgggg   3120

gtccaggtcg gggcgggcgg agggccaccc ggcctcgctc gggttgctgt gacgactcag   3180

ccctggcacg aagcccagcc cgcggcctgc tgggctctcg gctgagcaaa atctattccc   3240

agtccaccct gtcactgtcc actgtggcca acgaggccca caataacctc ggggtgaaga   3300

ggcccacgtc tcgggctccc tccccgtcag gtctcatgtc cccaagccgc ctgcctggaa   3360

gccgcgaacg ggactgggaa aatggcagca atgcctcctc cccagcgtca gtgcccgagt   3420

acacaggtcc acggctgtac aaagaaccca gcgccaagtc caacaagttc atcatccaca   3480

atgccctatc acactgctgc ctggcgggca aggtgaacga accgcagaag aatcgcattc   3540

tggaggaaat tgagaaaagc aaggccaacc acttcctgat cctctttcgc gactcgagct   3600

gccagttccg ggcgctctac acgctgtcgg gggagacaga ggagctgtcg cggctggcag   3660

ggtatgggcc ccggaccgtc acgcccgcca tggtggaagg catctacaag tacaactcgg   3720

accgcaagcg cttcacccag atccccgcca agaccatgtc catgagcgtc gatgccttca   3780

ccatccaggg acacctctgg cagggcaaga aacccaccac tcccaagaag ggcggcggca   3840

cccccaaata gccccacccg ggcggtccac gggccgggcc ctgtgtgctg cggccgccat   3900

cccctggagg acagtcagtc ggtattcctg ggtcctgtct gtccccaacc gtgtctgggt   3960

ggggctggag tctccaccct ctgactttga gtccagtcct gctgtggggg ctgagctggg   4020

aggttcaggg actcagggct cagctcagtc cccttgtctg tcctccccca cttcttgaat   4080

aaaataattt aaagagaagt tgaaaaaaaa aaaaaaaaaa                         4120


<210>  684
<211>  7361
<212>  DNA
<213>  Human

<400>  684
acgtgatctg tcagttcgcg gagagggaag aatatggccg ccgggtgtgg tgagggcgac     60

gcgcttgcag tcgccgtctc ttgcttcccc gtcctctgac atcgcctgca gccgagcggg    120

cccgttccgc cggagctgag gaccaggtat tcaaataaag ttaattgcag ctttctgtga    180

aaatgtcagt tttgatatca cagagcgtca taaattatgt agaggaagaa aacattcctg    240

ctctgaaagc tcttcttgaa aaatgcaaag atgtagatga gagaaatgag tgtggccaga    300

ctccactgat gatagctgcc gaacaaggca atctggaaat agtgaaggaa ttaattaaga    360

atggagctaa ctgcaatctg gaagatttgg ataattggac agcacttata tctgcatcga    420

aagaagggca tgtgcacatc gtagaggaac tactgaaatg tggggttaac ttggagcacc    480

gtgatatggg aggatggaca gctcttatgt gggcatgtta caaaggccgt actgacgtag    540

tagagttgct tctttctcat ggtgccaatc caagtgtcac tggtctgtac agtgtttacc    600

caatcatttg ggcagcaggg agaggccatg cagatatagt tcatctttta ctgcaaaatg    660

gtgctaaagt caactgctct gataagtatg gaaccacccc tttagtttgg gctgcacgaa    720

agggtcattt ggaatgtgtg aaacatttat tggccatggg agctgatgtg gatcaagaag    780

gagctaattc aatgactgca cttattgtgg cagtgaaagg aggttacaca cagtcagtaa    840

aagaaatttt gaagaggaat ccaaatgtaa acttaacaga taaagatgga aatacagctt    900

tgatgattgc atcaaaggag ggacatacgg agattgtgca ggatctgctc gacgctggaa    960

catatgtgaa catacctgac aggagtgggg atactgtgtt gattggcgct gtcagaggtg   1020

gtcatgttga aattgttcga gcgcttctcc aaaaatatgc tgatatagac attagaggac   1080

aggataataa aactgctttg tattgggctg ttgagaaagg aaatgcaaca atggtgagag   1140

atatcttaca gtgcaatcct gacactgaaa tatgcacaaa ggatggtgaa acgccactta   1200

taaaggctac caagatgaga aacattgaag tggtggagct gctgctagat aaaggtgcta   1260

aagtgtctgc tgtagataag aaaggagata ctcccttgca tattgctatt cgtggaagga   1320

gccggaaact ggcagaactg cttttaagaa atcccaaaga tgggcgatta ctttataggc   1380

ccaacaaagc aggcgagact ccttataata ttgactgtag ccatcagaag agtattttaa   1440

ctcaaatatt tggagccaga cacttgtctc ctactgaaac agacggtgac atgcttggat   1500

atgatttata tagcagtgcc ctggcagata ttctcagtga gcctaccatg cagccaccca   1560

tttgtgtggg gttatatgca cagtggggaa gtgggaaatc tttcttactc aagaaactag   1620

aagacgaaat gaaaaccttc gccggacaac agattgagcc tctctttcag ttctcatggc   1680

tcatagtgtt tcttaccctg ctactttgtg gagggcttgg tttattgttt gccttcacgg   1740

tccacccaaa tcttggaata gcagtgtcac tgagcttctt ggctctctta tatatattct   1800

ttattgtcat ttactttggt ggacgaagag aaggagagag ttggaattgg gcctgggtcc   1860

tcagcactag attggcaaga catattggat atttggaact cctccttaaa ttgatgtttg   1920

tgaatccacc tgagttgcca gagcagacta ctaaagcttt acctgtgagg tttttgttta   1980

cagattacaa tagactgtcc agtgtaggtg gagaaacttc tctggctgaa atgattgcaa   2040

ccctctcgga tgcttgtgaa agagagtttg gctttttggc aaccaggctt tttcgagtat   2100

tcaagactga agatactcag ggtaaaaaga aatggaaaaa aacatgttgt ctcccatctt   2160

ttgtcatctt cctttttatc attggctgca ttatatctgg aattactctt ctggctatat   2220

ttagagttga cccaaagcat ctgactgtaa atgctgtcct catatcaatc gcatctgtag   2280

tgggattggc ctttgtgttg aactgtcgta catggtggca agtgctggac tcgctcctga   2340

attcccaaag aaaacgcctc cataatgcag cctccaaact gcacaaattg aaaagtgaag   2400

gattcatgaa agttcttaaa tgtgaagtgg aattgatggc caggatggca aaaaccattg   2460

acagcttcac tcagaatcag acaaggctgg tggtcatcat cgatggatta gatgcctgtg   2520

agcaggacaa agtccttcag atgctggaca ctgtccgagt tctgttttca aaaggcccgt   2580

tcattgccat ttttgcaagt gatccacata ttatcataaa ggcaattaac cagaacctca   2640

atagtgtgct tcgggattca aatataaatg gccatgacta catgcgcaac atagtccact   2700

tgcctgtgtt ccttaatagt cgtggactaa gcaatgcaag aaaatttctc gtaacttcag   2760

caacaaatgg agacgttcca tgctcagata ctacagggat acaggaagat gctgacagaa   2820

gagtttcaca gaacagcctt ggggagatga caaaacttgg tagcaagaca gccctcaata   2880

gacgggacac ttaccgaaga aggcagatgc agaggaccat cactcgccag atgtcctttg   2940

atcttacaaa actgctggtt accgaggact ggttcagtga catcagtccc cagaccatga   3000

gaagattact taatattgtt tctgtgacag gacgattact gagagccaat cagattagtt   3060

tcaactggga caggcttgct agctggatca accttactga gcagtggcca taccggactt   3120

catggctcat attatatttg gaagagactg aaggtattcc agatcaaatg acattaaaaa   3180

ccatctacga aagaatatca aagaatattc caacaactaa ggatgttgag ccacttcttg   3240

aaattgatgg agatataaga aattttgaag tgtttttgtc ttcaaggacc ccagttcttg   3300

tggctcgaga tgtaaaagtc tttttgccat gcactgtaaa cctagatccc aaactacggg   3360

aaattattgc agatgttcgt gctgccagag agcagatcag tattggagga ctggcgtacc   3420

ccccgctccc tctacatgag ggtcctccta gggcgccatc agggtacagc cagcccccat   3480

ccgtgtgctc ttccacgtcc ttcaatgggc ccttcgcagg tggagtggtg tcaccacagc   3540

ctcacagcag ctattacagc ggcatgacgg gccctcagca tcccttctac aacaggccat   3600

tctttgcccc atacctttac acgccaaggt attaccctgg cggctcccaa catctcatct   3660

cacgtccatc agtaaaaacg agtttgccca gagatcagaa caatggccta gaagttatca   3720

aggaggatgc tgctgagggg ctttcttcac ccacagactc ctcgaggggg tcaggcccag   3780

ccccaggccc agtggtatta ctgaattcac tgaatgtgga tgcagtatgt gagaagctga   3840

aacaaataga agggctggac cagagtatgc tgcctcagta ttgtaccacg atcaaaaagg   3900

caaacataaa tggccgtgtg ttagctcagt gtaacattga tgagctgaag aaagagatga   3960

atatgaattt tggagactgg caccttttca gaagcacagt actagaaatg agaaacgcag   4020

aaagccacgt ggtccctgaa gacccacgtt tcctcagtga gagcagcagt ggcccagccc   4080

cgcacggtga gcctgctcgc cgcgcttccc acaacgagct gcctcacacc gagctctcca   4140

gccagacgcc ctacacactc aacttcagct tcgaagagct gaacacgctt ggcctggatg   4200

aaggtgcccc tcgtcacagt aatctaagtt ggcagtcaca aactcgcaga accccaagtc   4260

tttcgagtct caattcccag gattccagta ttgaaatttc aaagcttact gataaggtgc   4320

aggccgagta tagagatgcc tatagagaat acattgctca gatgtcccag ttagaagggg   4380

gccccgggtc tacaaccatt agtggcagat cttctccaca tagcacatat tacatgggtc   4440

agagttcatc agggggctct attcattcaa acctagagca agaaaagggg aaggatagtg   4500

aaccaaagcc cgatgatggg aggaagtcct ttctaatgaa gaggggagat gttatcgatt   4560

attcatcatc aggggtttcc accaacgatg cttcccccct ggatcctatc actgaagaag   4620

atgaaaaatc agatcagtca ggcagtaagc ttctcccagg caagaaatct tccgaaaggt   4680

caagcctctt ccagacagat ttgaagctta agggaagtgg gctgcgctat caaaaactcc   4740

caagtgacga ggatgaatct ggcacagaag aatcagataa cactccactg ctcaaagatg   4800

acaaagacag aaaagccgaa gggaaagtag agagagtgcc gaagtctcca gaacacagtg   4860

ctgagccgat cagaaccttc attaaagcca aagagtattt atcggatgcg ctccttgaca   4920

aaaaggattc atcggattca ggagtgagat ccagtgaaag ttctcccaat cactctctgc   4980

acaatgaagt ggcggatgac tcccagcttg aaaaggcaaa tctcatagag ctggaagatg   5040

acagtcacag cggaaagcgg ggaatcccac atagcctgag tggcctgcaa gatccaatta   5100

tagctcggat gtccatttgt tcagaagaca agaaaagccc ttccgaatgc agcttgatag   5160

ccagcagccc tgaagaaaac tggcctgcat gccagaaagc ctacaacctg aaccgaactc   5220

ccagcaccgt gactctgaac aacaatagtg ctccagccaa cagagccaat caaaatttcg   5280

atgagatgga gggaattagg gagacttctc aagtcatttt gaggcctagt tccagtccca   5340

acccaaccac tattcagaat gagaatctaa aaagcatgac acataagcga agccaacgtt   5400

caagttacac aaggctctcc aaagatcctc cggagctcca tgcagcagcc tcttctgaga   5460

gcacaggctt tggagaagaa agagaaagca ttctttgaga aaaacaagca aaggagaaga   5520

gtgttactgt acccttatga cagaattgtc ctggattttg actccatcca cgcccatcac   5580

ctttctacat tttgctgaca gataactaac cgatgatgag gccgaggtaa aagagacatc   5640

tgcagtgtga cagaagggag catgagaagc atggctcacc agccagcctc tgtggtcttt   5700

gtaattagaa gcttcagaac tcactaatac tactgtacct ttcattggcg cattacccca   5760

taaaactttt tgagacgagg tgagatctga gtataaagat aggtcagaag tattttaaag   5820

ggcttaatgt gccaaaaaga aaaaaagcta gagacccttt ttgcaaacat ttggtgacca   5880

cacatttgag ggaagacgtg gcgttaggtg aagcagaagc aaaccctgct cttaggggct   5940

cacctaggtg agtgcacagc ctgtgacgct acagggagag gctgagtaaa ccgagatcca   6000

gcgttctgta tggcaggggt attgcttatc acagaggttc tgaagagtag gaagtacata   6060

atgaagaggg ctttaaaaat tgccaacaaa gtgagtcacc agggctggca gtagtgtgac   6120

ggggctgtcc tgagctgtta ggagagtaga tgcggggagg gctggtgacc tccgtgggtt   6180

tatatgtcgg aaactcttct ctccaaatcc caggcctggc ttccagcacc atccagctgt   6240

gcccaagaag ccaccctggt ctgttctcca actcttttaa atggtgccca acttttctaa   6300

gtgagcttag caatgagaag aaaaaaaaac atgaattctt tttctggaaa atcagggaga   6360

catgggtaat aataggtact aataaatatt tatagatgag tgaatgagga aataattaca   6420

tcaaaaaggt cagtgacaat tgataaatga caaggaaata tttaattagg taaaactaaa   6480

tcattgctct ctatactagg atagacttta tctacttcat ctgttcctaa gtcagcatgt   6540

tagttctggg gaaggatcat aagaaaggaa atacttttta aaaaaaaatt tggaaacatg   6600

taacaaagca agggtaaaat atatatatat atctatataa gtgctgtgac tgtaaaagtg   6660

tactttccat taattattag ccgagttaag agaatggtca cattgaagta ctgtgtggac   6720

tagaaatgta ccctgtcatc atgcaatgaa atattgttat cgttttaaca tagctcattt   6780

atgtagaatg aattctggtg gtttacccca agtcacagtt aggacggtag atggtgagat   6840

cgcagatgcg ctattatcta gattcagtgt tacattttcg atgtttatca ctcagtgggt   6900

ttttattaat atgctgatta agttatttac tgggccagtc attgtgctaa atagttgctc   6960

ttttgtgttt cattgccttg atgtttgagt gtaatctagc attttaatac agtgtttatt   7020

ttgcatgatc tttaacaaat gttttaagca attttaaaaa ggcaggatgt tattgacatt   7080

atacactgaa gtcttaacat tttaacattt atagtgctta tttgcaaaat tgtataatta   7140

ggaattattt cagagacaat gttttctttt tcaggtgagt agttgccgcg taatatcatt   7200

ggagtacatt ctttatactg tttgtgaaat taatactagc atattaagtg tacaaataga   7260

tttagaaaac aataaaaaat tgcatgctat tctgactcat gaatttttat tcactatgat   7320

gattcacatt ttgattaaaa ataaaagtag tttgtgtgtt t                       7361


<210>  685
<211>  1753
<212>  DNA
<213>  Human

<400>  685
cagccccgcc cctacctgtg gaagcccagc cgcccgctcc cgcggataaa aggcgcggag     60

tgtccccgag gtcagcgagt gcgcgctcct cctcgcccgc cgctaggtcc atcccggccc    120

agccaccatg tccatccact tcagctcccc ggtattcacc tcgcgctcag ccgccttctc    180

gggccgcggc gcccaggtgc gcctgagctc cgctcgcccc ggcggccttg gcagcagcag    240

cctctacggc ctcggcgcct cacggccgcg cgtggccgtg cgctctgcct atgggggccc    300

ggtgggcgcc ggcatccgcg aggtcaccat taaccagagc ctgctggccc cgctgcggct    360

ggacgccgac ccctccctcc agcgggtgcg ccaggaggag agcgagcaga tcaagaccct    420

caacaacaag tttgcctcct tcatcgacaa ggtgcggttt ctggagcagc agaacaagct    480

gctggagacc aagtggacgc tgctgcagga gcagaagtcg gccaagagca gccgcctccc    540

agacatcttt gaggcccaga ttgctggcct tcggggtcag cttgaggcac tgcaggtgga    600

tgggggccgc ctggaggcgg agctgcggag catgcaggat gtggtggagg acttcaagaa    660

taagtacgaa gatgaaatta accaccgcac agctgctgag aatgagtttg tggtgctgaa    720

gaaggatgtg gatgctgcct acatgagcaa ggtggagctg gaggccaagg tggatgccct    780

gaatgatgag atcaacttcc tcaggaccct caatgagacg gagttgacag agctgcagtc    840

ccagatctcc gacacatctg tggtgctgtc catggacaac agtcgctccc tggacctgga    900

cggcatcatc gctgaggtca aggcgcagta tgaggagatg gccaaatgca gccgggctga    960

ggctgaagcc tggtaccaga ccaagtttga gaccctccag gcccaggctg ggaagcatgg   1020

ggacgacctc cggaataccc ggaatgagat ttcagagatg aaccgggcca tccagaggct   1080

gcaggctgag atcgacaaca tcaagaacca gcgtgccaag ttggaggccg ccattgccga   1140

ggctgaggag cgtggggagc tggcgctcaa ggatgctcgt gccaagcagg aggagctgga   1200

agccgccctg cagcggggca agcaggatat ggcacggcag ctgcgtgagt accaggaact   1260

catgagcgtg aagctggccc tggacatcga gatcgccacc taccgcaagc tgctggaggg   1320

cgaggagagc cggttggctg gagatggagt gggagccgtg aatatctctg tgatgaattc   1380

cactggtggc agtagcagtg gcggtggcat tgggctgacc ctcgggggaa ccatgggcag   1440

caatgccctg agcttctcca gcagtgcggg tcctgggctc ctgaaggctt attccatccg   1500

gaccgcatcc gccagtcgca ggagtgcccg cgactgagcc gcctcccacc actccactcc   1560

tccagccacc acccacaatc acaagaagat tcccacccct gcctcccatg cctggtccca   1620

agacagtgag acagtctgga aagtgatgtc agaatagctt ccaataaagc agcctcattc   1680

tgaggcctga gtgatccacg tgaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1740

aaaaaaaaaa aaa                                                      1753


<210>  686
<211>  954
<212>  DNA
<213>  Human

<400>  686
tttgatagag aagggacagg gaacagaacc ttcgcccccc gcctgagcag ctggtagact     60

agatatcttc caaacattat ctcatttact tccctggagt tacaaatagg tagatttcat    120

gtccgttgag gggtgagaaa gctgaaactt tgagacttaa gaatcctggc cgaggtcagc    180

ctcctccgaa gcttcatctc ttgccaccac tttctggtgc acacctagga cagatttcaa    240

tccctgagat cccaggatga aacctatgtt tgccaaatac cagctactgt gccagaagag    300

atcatggaac caggtgtgga aagctgcttg agaagaggag ccaaaacatc atagttgaac    360

cgtcctggaa tagaaactcg ccctgaattc tttcttgtgt gaaatccaag agccctctct    420

tggggttgga tcgggaccct gttcctgtaa caagtccaca atgccagaga attaaagaga    480

accacaaagc tgaacctcaa aaagttagcc tggcgagggg aggatgatga gatttcccct    540

gttgtcacat aaacaaggaa gtaaaggggg ccccttgtgc tctcagaact ccaagcatga    600

aacgatagca aagggaaaaa cagctaagtg tttcctggct gaattttatt ttgctttcag    660

tttctgccat ttcagttcct gttatcgtgc tttgaggtgc actgaactgc agcaaaccca    720

ggggatccaa ggctacgttg aaaagccttt gaccacagtg cagggagcag aagacattaa    780

tgacgtgatg tcgacacagc ccgcactcag gatcctccag gaaaagaaca cagagataac    840

cccggatcga tggtactttt tgaaaatgct ttattgcaaa agagtggcta gggttttaca    900

agggctatga agaaacatat taaggttaat aaagcttttt attgagtgtt taaa          954


<210>  687
<211>  3378
<212>  DNA
<213>  Human

<400>  687
acagctgcac cgccgagctg cgagcggctg cgagcgagag agcgtaagag caagagagct     60

agagagcgag caacgggcac tcgccccacg cctcccctca gccccaccgc gcgctccgct    120

tgcctctcca ccccgcccga ctctacccgg cccggtccct gcgcgggcac agcccagagc    180

tctggggcgg tgcaggcagc ctcgggactc tccggcgcgc cgccgcgtcc ccagacaaag    240

gcttggccgg cggccccggc ccgctgcgcc ctcgctcccc gcctccccag ctcttctccg    300

ctcttccccc ccgcgcttgg ctcggcgcgc tccggccggc cgcaaagttt cccgggcggc    360

agcggcggct gcgcctcgct tcagcgatgg ccgcggagct gagcatgggg ccagagctgc    420

ccaccagccc gctggccatg gagtatgtca acgacttcga cctgctcaag ttcgacgtga    480

agaaggagcc actggggcgc gcggagcgtc cgggcaggcc ctgcacacgc ctgcagccag    540

ccggctcggt gtcctccaca ccgctcagca ctccgtgtag ctccgtgccc tcgtcgccca    600

gcttcagccc gaccgaacag aagacacacc tcgaggatct gtactggatg gcgagcaact    660

accagcagat gaaccccgag gcgctcaacc tgacgcccga ggacgcggtg gaagcgctca    720

tcggctcgca cccagtgcca cagccgctgc aaagcttcga cagctttcgc ggcgctcacc    780

accaccacca tcaccaccac cctcacccgc accacgcgta cccgggcgcc ggcgtggccc    840

acgacgagct gggcccgcac gctcacccgc accatcacca tcatcaccaa gcgtcgccgc    900

cgccgtccag cgccgctagc ccggcgcaac agctgcccac tagccacccc gggcccgggc    960

cgcacgcgac ggcctcggcg acggcggcgg gcggcaacgg cagcgtggag gaccgcttct   1020

ccgacgacca gctcgtgtcc atgtccgtgc gcgagctgaa ccgccacctg cggggcttca   1080

ccaaggacga ggtgatccgc ctgaagcaga agcggcggac cctgaagaac cggggctacg   1140

cccagtcttg caggtataaa cgcgtccagc agaagcacca cctggagaat gagaagacgc   1200

agctcattca gcaggtggag cagcttaagc aggaggtgtc ccggctggcc cgcgagagag   1260

acgcctacaa ggtcaagtgc gagaaactcg ccaactccgg cttcagggag gcgggctcca   1320

ccagcgacag cccctcctct cccgagttct ttctgtgagt cgtggccggt cctggccccc   1380

gcccttgccc cggcccggac tccctgtccc acgtccctag tcccagacta ccccggaccc   1440

tgtccctgcc gcggccccag ccttgacctg tttgacttga gcgagaggga ggaagggcgc   1500

gcgggccgcg ggcgacgggc gggtgcgcgg gcgggcaggg gaccttggct aaggcgagag   1560

tagcgcacgc cagcgccgcc tcctagactc gagcagagcc ggagagagag acgagagggt   1620

gggaggtccc ggagtaactt ctctccaggc tgaagggcgg cgaggcatag tcccgagaag   1680

tcaccaaggc catctggaga ctcctggctt tctgaacttt gcgcgttaag ccgggacagc   1740

tgctttgctg cccggagagt agtccgcgcc aggaagagag caacgaggaa aggagaggga   1800

ctctggcgtc ccggcaggcg agaggcgagg ctgagcgaaa gaaggaagga cagacggacc   1860

tgtctgtcag agttcggaga acactggctc tcagccctga gacacaggcc tcagttagga   1920

cgctcggcgc ccaaatctca tcagttttat tgcctgctcg attatataga aaaatacaaa   1980

aaatctgcat taaaaatatt aatcctgcat gctggacatg tatggtaata atttctattt   2040

tgtaccattt tcttgtttaa ctttagcatg ttgttgatca tggatcatac tccccttgtt   2100

tctttgggtg agaagggatc gcagtttgga aactccggcg gctgcgtgcg gggtttcagt   2160

cccagctgta ggcttgtaaa tacccgcccc gccaaaccgc atagagaacg tggcagcaag   2220

ctgagggtct ttgtttgggt ttattattac ggtatttttg tttgtaagtt aaaaagaaaa   2280

aaaaaaagaa aaagttccgg gcattttgca tcagaaaaca actttgtctt ggggcacact   2340

tggaagttgc atgttttctt tccttccctt atccccattc ggtcctcttt ttcctctctc   2400

gctttagttt tcaaccttgt tggtgctgag agagagaacc gagaggtccc agtacaaggg   2460

cagggcaggg cagggaagct gccaagctcc gcaccccaga ggagtgttct ggactacagc   2520

cttgtcttat ggtcaaattg atacccttaa taagaaagga aaggaaagga aaacagatcc   2580

tcccctctgc tttttattgt aaccagaatc accctgaggt cccttctgaa ccctctgggc   2640

ctgcgctaat tgtaggagcc acagcgctcc tagggtgaga ggcttagcca tccctgaccc   2700

tggcagtgca ctggtaagca gacactgcac tgaaccaact gctatgctca gaatgtacca   2760

gaaacccaaa cattggcaag taattttgca actttcaagt gcgttcttta gaccaatgca   2820

ttgcgtttct ttccctgctt ttgagatagt aggaagagtt cttggtggtg tcccccccct   2880

tcaattcttc agttgtatag tagttatagg gaagatatgg gtgtttttct ttattattac   2940

tttttttttt ctgcaggtca gtaaaaggat ttaagttgca ctgacaaaaa taccaaaata   3000

aaagtgtatt tttaagttcc catttgaaat tgctggcgct gctggccgga tgcatttttg   3060

agtttgtatt agttgataaa ttaacagtaa taacaagatt gtatgaaccg catggtgctt   3120

gcagttttaa atattgtgga tatttgtcct gcatcagaaa cgagctttgg tttttacaga   3180

ttcaactgtg ttgaaatcaa acctgccgca acagaaattg tttttatttc atgtaaaata   3240

agggatcaat ttcaaaccct gcttatgata tgaaaatatt aaaacctagt ctattgtagt   3300

tttattcaga ctggtttctg ttttttggtt attaaaatgg tttcctattt tgcttattaa   3360

aaaaaaaaaa aaaaaaaa                                                 3378


<210>  688
<211>  2383
<212>  DNA
<213>  Human

<400>  688
cgggtcggtg acgtcaccgc atgactgggt ttttatgaat gaaaggaatc ctgtgagtga     60

gtaattccgg gaagctcgcc ttacaactcc gcgcggcctc ggccccctgc gccgcccgcc    120

ccacaacaaa actcagcgca gcgctcccgg gcgcccggtt cagagcgacc tgcggctcag    180

agcggagggg agactgaccg gagcgcggat cgggacagcg gccgggacag cggcgagacg    240

cgcgtgtgtg agcgcgccgg accaagcggg cccagaagcg gatcaagcga gagctgagcg    300

agaacacgcc gcacctgtcg gacgaggcgc tgatggggct gtcggtgcgc gagctgaacc    360

ggcatctgcg cgggctctcc gccgaggagg tgacacggct caagcagcgg cgccgcacac    420

tcaaaaaccg tggctacgcc gccagctgcc gcgtgaagcg cgtgtgccag aaggaggagc    480

tgcagaagca gaagtcggag ctggagcgcg aggtggacaa gctggcgcgc gagaacgccg    540

ccatgcgcct ggagctcgac gcgctgcgcg gcaagtgcga ggcgctgcag ggcttcgcgc    600

gctccgtggc cgccgcccgc gggcccgcca cgctcgtggc gccggccagc gtcatcacca    660

tcgtcaagtc caccccgggc tcggggtctg gccccgccca cggcccggac cccgcccacg    720

gcccggcctc ctgctcctag tgcccgcccc cgccatgcct cagccacgcc cctccggcct    780

cagctccctc cccaaagtgc ctgagcgccg cctctgtgcc caggtcccat ttctctgcag    840

cactggcccc ttggtgcaca cacattccct tcgtgggccc tgtcttcctc ttgcagcccc    900

ccaaactggg accgaatgac cctgggaagg ggaacttggg taggttgggg atggggcaga    960

ggtctggatc tgggatcgcc cttggctgaa agtttagcct ttttagattg agagatacag   1020

agccggctta gagaacagct gttgggggag aagagggcac ccctcatctt ggaaactgct   1080

cttattgtgc caatatgccc tccaaaccct cccaggattc aaagctaggt ttggctgtct   1140

gtgacttacg ggaccgtcct gctgagaaat tgcactgaag agatgccccc acctctggtt   1200

gggcctgggg gtgcctggcc ttccgaaact aaaagagtgg gtgggaagac tagtgaaacc   1260

cagttcacgg atggggaaac aggcctgagg tcacatttca cttagtggtt gtgttgggac   1320

caaaacctgg gtgtcctcac tgctgccctg agtccagcca tggttttcag ggggacagtg   1380

gacagggact cagaaatgtg gtgggagggc ctccctggct tgggagaccg ctctctgcaa   1440

gggaggggga gagaagcaga gggagagaga aggtgacacg gatggaagag tgggaaggag   1500

ctggcctggc tcagccctag gctgtccctg cagccagggt gtccgggggc tggccagtca   1560

gagaaagggg gccatggact gctgtggcaa atagggagac aaggagacag accctgcagt   1620

cctactacag tctggagtgg ggtcctaaga agaagggtcc cacctcaacc cctgtcagtg   1680

tccactgtgg ggtgggggct gacccctgcc tttgattgtc attctcctgg gaagcccagt   1740

ctcagtccct cccccaacac tgtccacact gcccctcccc actgtttatt tattgcacgg   1800

atctaagtta ttctccccag ccagagcccg agctcctgct ccctgggaaa agtggcgtat   1860

ggccctgagc tgggctttat attttatatc tgcaaataaa tcacatttta tcttatattt   1920

agggaaagcc ggagagcaac aacaaaaaat gtttaagccg ggcgcggtgg ctcacatctg   1980

taatcccagc actttgggag tccaaggagg gggatcgctt gagtccagga gtttgagacc   2040

agcctggaca acatggtgaa accccatctc tacaaaaaat acaaaaatta gccatgcatg   2100

gtggctcatg cctgtagtcc cagctacttg ggaggctgag gcaggaggat cacttaagcc   2160

cagaaggcag aggttgtagt gagctgagat cgcaccactg cactccagcc tgggcaacat   2220

agcaaaatcc tgtctcaaaa aaaaagttaa aaaatattgc ccggctccta gaatttattt   2280

atttcctgac ttacagcaag cgagttatcg tcttctgtat tttgtagact ttctaaataa   2340

agtcaaattc tttctttttc cacagagaat aaaaaaaaaa aaa                     2383


<210>  689
<211>  1880
<212>  DNA
<213>  Human

<400>  689
tctctgtgcg ttgaagccgg agaccgcggc ggcctcagcg aggaccctcc gccccggagc     60

cgccggccgg agccgcagcc tctgccgcag cgcccccgcc acctgtcccc tccccctccg    120

cctccgccgg agccgcctcg tgcactctgg ggtatggccg tcaatgtgta ctccacatct    180

gtgaccagtg aaaatctgag tcgccatgat atgcttgcat gggtcaacga ctccctgcac    240

ctcaactata ccaagataga acagctttgt tcaggggcag cctactgcca gttcatggac    300

atgctcttcc ccggctgtgt gcacttgagg aaagtgaagt tccaggccaa actagagcat    360

gaatacatcc acaacttcaa ggtgctgcaa gcagctttca agaagatggg tgttgacaaa    420

atcattcctg tagagaaatt agtgaaagga aaattccaag ataattttga gtttattcag    480

tggtttaaga aattctttga cgcaaactat gatggaaagg attacaaccc tctgctggcg    540

cggcagggcc aggacgtagc gccacctcct aacccaggtg atcagatctt caacaaatcc    600

aagaaactca ttggcacagc agttccacag aggacgtccc ccacaggccc aaaaaacatg    660

cagacctctg gccggctgag caatgtggcc cccccctgca ttctccggaa gaatcctcca    720

tcagcccgaa atggcggcca tgagactgat gcccaaattc ttgaactcaa ccaacagctg    780

gtggacttga agctgacagt ggatgggctg gagaaggaac gtgacttcta cttcagcaaa    840

cttcgtgaca tcgagctcat ctgccaggag catgaaagtg aaaacagccc tgttatctca    900

ggcatcattg gcatcctcta tgccacagag gaaggattcg caccccctga ggacgatgag    960

attgaagagc atcaacaaga agaccaggac gagtactgag ggcggccgca gccctggctg   1020

actgcacggc ttccccgtgc ctccctccct gctccactcc cacattatag tcctttccta   1080

acacggtcgg ccgggtgctt tgtgtcagtg ctgcagcact ggggagccag gcgagggggg   1140

cttgggggca tggggccgga aagcaggcag aagcccgtcc tgggtggtgc tggcccagtt   1200

ggtgggaccc ctgtccacac ccaccctatt tatttccgtt gtctctctgc tgtgtcgccc   1260

aacacttccc agggtgctgc tgccacccgc cccagccagc cacctgctcc tgacagccag   1320

cagctgtgta tttgacaaag tcattggtat atttttactt actggattct ccttgcactt   1380

tacctgttct tttccagagc tgacagcacg ggctccggcg cagtgtgcct ggcttggctt   1440

cccttcccca tggctggggg ctggggtagg actcacccat tctaatttat tttgtctttt   1500

ggcttctcag tagctaaggg gaaggctgat gtcaggagag ggagaggggg ctgaggaggt   1560

agtgctgtag gcccaggggg tcagggaaag ggaggggggc atgtgaggga tggaaatgac   1620

ctcctggcac caggctcacc cacccaaggc cccctgcccc agcactgaat cccagcgctg   1680

ccctgaggcc cccagccact ccctccagca gcctggttca ccacacaaac tctgcctgga   1740

ccccattgtc tgtctgcttc ccacctgccc tccccacccc ctgcccctcg ggcaccagcc   1800

tgcatatgtg ttcactttta tttaaataaa cttgtgtggt aaaagtacat gccatgtgtc   1860

cctcaactga aaaaaaaaaa                                               1880


<210>  690
<211>  1391
<212>  DNA
<213>  Human

<400>  690
agccccggac gggagcgggc ccacggggct gcaggtgtgg agccccctgg agctgagatc     60

aggatgttcc gcttcatgag ggacgtggag cctgaggatc ccatgttcct gatggatccc    120

tttgctattc accgtcagca tatgagccgt atgttgtcag gtggctttgg atatagcccc    180

ttcctcagca tcacagatgg caacatgcca gggaccaggc ctgccagccg ccggatgcag    240

caggctggag ctgtctcccc ctttgggatg ctgggaatgt cgggtggttt catggacatg    300

tttgggatga tgaatgacat gattggaaac atggaacaca tgacagctgg aggcaattgc    360

cagaccttct catcttccac tgtcatctcc tactccaata cgggtgatgg tgcccccaag    420

gtctaccaag agacatcaga gatgcgctcg gcaccaggcg ggatccggga gacacggagg    480

actgttcggg attcagacag tggactggag cagatgtcca ttgggcatca catccgggac    540

agggctcaca tcctccagcg ctcccgaaac catcgcacgg gggaccagga ggagcggcag    600

gactatatca acctggatga gagtgaggcc gcagcgtttg atgacgagtg gcggcgggag    660

acctcccgat tccggcagca gcgtcccctg gagtttcggc ggcttgagtc ctcaggggct    720

gggggacgaa gggcggaggg gcctccccgc ctggccatcc agggacctga ggactcccct    780

tcccgacagt cccgccgcta tgactggtga gggccccggg ccctcagcct ctcttgtaca    840

ggctgagagg ctgagaaatc atcccctgaa taactttttc ctctcgattc ccatccccaa    900

tttaatatta aattaacagg caagccggcc cccacctctc cctgggggtc tcagggagaa    960

cctttcacgg caccctttcc ctaccttttc cttctttaat ctcctggttt accattgatg   1020

acttcgcctc tgcatctact gacttgattt ttcattctgc cactccatct tcaaaccccc   1080

tcacctttcc catcctactc ctgccatgca ttgaagggtc aatgcatttt ggggtgagct   1140

ctgggtttag gggccccctc catccctcag ctaccctgga tctttgccca cctcttcctc   1200

agagccccca ctgaggggcc gtagccctat ctagggctgt ggaaggagca gactggttcc   1260

taactctctc cctcctcctg cccacacaca tcaaaagaat cttccctaca cccttctctg   1320

cctttatttt ttgatttgtg caacttgtaa ctaggtgttt atggaataaa ggagaatgga   1380

aaaaagacca a                                                        1391


<210>  691
<211>  2564
<212>  DNA
<213>  Human

<400>  691
cttgctcgcg gagagaggag ctaggagcct cggccaatgg gagccggcgt tgttggaggc     60

cacggcggcg cagccccaaa gcgagcgaag ctagggtcgc cgccactgcc gcaggaggcg    120

tgaggggata aaaacattca gatggcagat cacagttttt cagatggggt tccttcagat    180

tccgtggaag ctgctaaaaa tgcaagtaac acagaaaagc tcacagatca ggtgatgcag    240

aatcctcgag ttctggcagc tttacaggag cgacttgaca atgtccctca caccccttcc    300

agctacatcg aaactttacc taaagcagta aaaagaagaa ttaatgcatt gaaacaactt    360

caggtgagat gtgctcacat agaagccaag ttctatgaag aggtacatga cttggaaaga    420

aagtatgcag cgctatacca gcctctcttt gacaagagaa gagaatttat caccggcgat    480

gttgaaccaa cagatgcgga atcggaatgg cacagtgaaa atgaagagga agagaaattg    540

gctggagaca tgaaaagtaa agtagtcgtc acagaaaaag cagcggcaac ggctgaagag    600

ccagatccca aaggaattcc agagttctgg tttaccatct tcagaaatgt ggacatgctg    660

agtgaattag tccaggaata tgatgaacca atcttgaaac acctgcagga tattaaagtg    720

aaattttctg accctggaca gcctatgtct tttgtgttag agttccactt tgaacccaac    780

gactacttta ccaactcagt cctgacaaaa acctacaaga tgaaatcaga accagataag    840

gctgatccct tttcctttga aggtcctgag attgtggact gtgacgggtg tactattgac    900

tggaagaaag gaaagaatgt tactgtcaaa accatcaaga aaaagcagaa gcataagggt    960

cgaggcactg ttagaacaat tacgaaacaa gtacccaatg agtccttttt caacttcttc   1020

aatccattga aagcatccgg ggatggagaa tcactggatg aagattctga attcacatta   1080

gcctctgatt ttgaaattgg acactttttc cgtgagcgga tagtcccgcg ggctgtgctg   1140

tacttcactg gggaggccat agaagatgat gacaattttg aagaaggtga agaaggagaa   1200

gaggaggaat tagaaggtga cgaggaggga gaagacgagg atgatgcgga aattaacccc   1260

aaggtgtaat ttttgtctgt taatcattca tacgtttcta gaaggaaccc agccagccgg   1320

cggaatgcaa gcagcagtag gaagcggagg cgggtgcctg gcagaccggc tgtcgggact   1380

ccaggcctgt gggcggggcc tcggtccttg ccgcagcaca atcccgtgga cagagcttac   1440

tccatctaac tcgttttcaa gtgcatgatt ttcactttca cttttccttt ttccttatta   1500

ttttgcttaa cttgtacagt ggcaactgaa atgcatttca gaaataggag gtttcgtcca   1560

gcaccctctg cagccttggt gcctgtagct ctggacttcc ctgggccttt ccctgtggga   1620

gggccctgta gaccacatca gggtggggtg ggggtcactt ggcaaaaagg gccgaggtct   1680

ggtgatgtgg ttcccaggat ctggaacctc tcccacccct cctgcagttg gactgaattc   1740

ttccctttca tccgaagaaa cccacttgct gtttccagcc gctgaatctg ctgagtgtgc   1800

agcctgcatc acctgctgta tgccgatcat ctcagaaagg gctgtgtaga gtagggccct   1860

gttctcctta ggatgttgct tcttgatttt tttttttttt taggggtggg tcagggttgt   1920

gacacaccag cccaggtgag agctgctgcg ggtcacctca tatttattta tcccttcttg   1980

cctgtgagga ctgcggcttt tcgctgtggc tcgtccttaa cgtttctgaa ccaccttggt   2040

gccctgagca ggaagatgtg ccacttccta gcaggcgcaa ggcctgtgcg gaagaaacgc   2100

cgctccctgc caccagggct gaagatgcga gcccgtcctc atgacgcagg cgccaccctg   2160

ctgccggagc cgggcttcgg cagtcttctc cactgaggga ctgggctggg aagtcctgcg   2220

tttcagtgga gcgtatgagc gtcaagtcct gctttctcag tagccccatt gcggggcccc   2280

accattcatc ctgtctgaag gtcctgggtt tggtgtgacc gcttggcggc tggtgggtgg   2340

ggttttcaag tgggtgacgg cgctctccgg cagccgggga tggccgtgtc cgcactgacc   2400

aggcctgtgg agagtgctcg gcctaacctt agaacacatt tgtaactgaa tacagtgttt   2460

tcaatttgta cagaatagtt agaatattct attaaagtgg tgaaacattg agtcagcaaa   2520

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa                    2564


<210>  692
<211>  2429
<212>  DNA
<213>  Human

<400>  692
acactccacc cctactcgcc ctctctctct ctgcttcttt ccttttctct ctcatggtag     60

ggttatgagt cagttgccaa aaggtgggga catttcctga tgcatttgca acactgagaa    120

gttatcttaa gggaggctgg gccccattct actcatctgg cccagaaagt gaacaccttg    180

ggggccacta aggcagccct gctaggggag acgctccaac ctgtcttctc tctgtctcct    240

ggcagctctc ttggcctcct agtttctacc taatcatgtc cctggtggag gccatcagcc    300

tctggaatga aggggtgctg gcagcggaca agaaggactg gaagggagcc ctggatgcct    360

tcagtgccgt ccaggacccc cactcccgga tttgcttcaa cattggctgc atgtacacta    420

tcctgaagaa catgactgaa gcagagaagg cctttaccag aagcattaac cgagacaagc    480

acttggcagt ggcttacttc caacgaggga tgctctacta ccagacagag aaatatgatt    540

tggctatcaa agaccttaaa gaagccttga ttcagcttcg agggaaccag ctgatagact    600

ataagatcct ggggctccag ttcaagctgt ttgcctgtga ggtgttatat aacattgctt    660

tcatgtatgc caagaaggag gaatggaaaa aagctgaaga acagttagca ttggccacga    720

gcatgaagtc tgagcccaga cattccaaaa tcgacaaggc gatggagtgt gtctggaagc    780

agaagctata tgagccagtg gtgatccctg tgggcaagct gtttcgacca aatgagagac    840

aagtggctca gctggccaag aaggattacc taggcaaggc gacggtcgtg gcatctgtgg    900

tggatcaaga cagtttctct gggtttgccc ctctgcaacc acaggcagct gagcctccac    960

ccagaccgaa aaccccagag atcttcaggg ctctggaagg ggaggctcac cgtgtgctat   1020

ttgggtttgt gcctgagaca aaagaagagc tccaggtcat gccagggaac attgtctttg   1080

tcttgaagaa gggcaatgat aactgggcca cggtcatgtt caacgggcag aaggggcttg   1140

ttccctgcaa ctaccttgaa ccagttgagc tgcggatcca ccctcagcag cagccccagg   1200

aggaaagctc tccgcagtcc gacatcccag ctcctcctag ttccaaagcc cctggaagac   1260

cccagctgtc accaggccag aaacaaaaag aagagcctaa ggaagtgaag ctcagtgttc   1320

ccatgcccta cacactcaag gtgcactaca agtacacggt agtcatgaag actcagcccg   1380

ggctccccta cagccaggtc cgggacatgg tgtctaagaa actggagctc cggctggaac   1440

acactaagct gagctatcgg cctcgggaca gcaatgagct ggtgcccctt tcagaagaca   1500

gcatgaagga tgcctggggc caggtgaaaa actactgcct gactctgtgg tgtgagaaca   1560

cagtgggtga ccaaggcttt ccagatgaac ccaaggaaag tgaaaaagct gatgctaata   1620

accagacaac agaacctcag cttaagaaag gcagccaagt ggaggcactc ttcagttatg   1680

aggctaccca accagaggac ctggagtttc aggaagggga tataatcctg gtgttatcaa   1740

aggtgaatga agaatggctg gaaggggagt gcaaagggaa ggtgggcatt ttccccaaag   1800

tttttgttga agactgcgca actacagatt tggaaagcac tcggagagaa gtctaggatg   1860

tttcacaaac tacaaagctg aagaaaatga agccctatta cttgtttgta agatttagca   1920

cccttctgct gtatactgta ctgagacatt acagtttgga agtgttaact atttattccc   1980

tgttaaaatt taacctacta gacaatgatg tgagtaccca ggatgatttc ctggggcaca   2040

gtgggtgagg agatggggac aggtgaatgg aggagttagg ggagaggaaa agtggatgga   2100

agtgtctgga aagggcacga gagagtcttc caggtactga tcctgtttct tgctctgagt   2160

gctagctagc cagctgtgtt cacactgtaa acattcatca agctgtacat ttggtgcact   2220

tttctgtgtc ataccacaat aaaaaaaaac ctagcatctt acaaaaacaa gacacccaag   2280

tccaggccca aggagtaagt acaaatattc ctgtttctga accattactg taattggctc   2340

ttaaggcttg aagtaacctt ataggttact cataaggcat atacaaataa acttgtttgt   2400

tttctttttt caaaaaaaaa aaaaaaaaa                                     2429


<210>  693
<211>  2859
<212>  DNA
<213>  Human

<400>  693
aaatcaggga ggcgcagctc ctacaccaac gcctttccgg ggctccgggt gtgtttgttc     60

caactgttta aactgtttca aagcgtccga actccagcga ccttcgcaaa caactcttta    120

tctcgcgggc gagagcgctg cccttatttg cgggggaggg caaactgaac gccggcaccg    180

gggagctaac ggagacctcc tctaggtccc ccgcctgctg ggaccccagc tggcagtccc    240

ttcccgcccc cggaccgcga gcttcttgcg tcagccccgg cgcgggtggg ggattttcgg    300

aagctcagcc cgcgcggccg gcgggggaag gaagggcccg gactcttgcc ccgcccttgt    360

ggggcgggag gcggagcggg gcaggggccc gccggcgtgt agccgattac cgagtgccgg    420

ggagcccgga ggagccgccg acgcagccgc caccgccgcc gccgccgcca ccagagccgc    480

cctgtccgcg ccgcgcctcg gcagccggaa cagggccgcc gtcggggagc cccaacacac    540

ggtccacagc tcatcatgat ggacttggag ctgccgccgc cgggactccc gtcccagcag    600

gacatggatt tgattgacat actttggagg caagatatag atcttggagt aagtcgagaa    660

gtatttgact tcagtcagcg acggaaagag tatgagctgg aaaaacagaa aaaacttgaa    720

aaggaaagac aagaacaact ccaaaaggag caagagaaag cctttttcgc tcagttacaa    780

ctagatgaag agacaggtga atttctccca attcagccag cccagcacat ccagtcagaa    840

accagtggat ctgccaacta ctcccaggtt gcccacattc ccaaatcaga tgctttgtac    900

tttgatgact gcatgcagct tttggcgcag acattcccgt ttgtagatga caatgaggtt    960

tcttcggcta cgtttcagtc acttgttcct gatattcccg gtcacatcga gagcccagtc   1020

ttcattgcta ctaatcaggc tcagtcacct gaaacttctg ttgctcaggt agcccctgtt   1080

gatttagacg gtatgcaaca ggacattgag caagtttggg aggagctatt atccattcct   1140

gagttacagt gtcttaatat tgaaaatgac aagctggttg agactaccat ggttccaagt   1200

ccagaagcca aactgacaga agttgacaat tatcattttt actcatctat accctcaatg   1260

gaaaaagaag taggtaactg tagtccacat tttcttaatg cttttgagga ttccttcagc   1320

agcatcctct ccacagaaga ccccaaccag ttgacagtga actcattaaa ttcagatgcc   1380

acagtcaaca cagattttgg tgatgaattt tattctgctt tcatagctga gcccagtatc   1440

agcaacagca tgccctcacc tgctacttta agccattcac tctctgaact tctaaatggg   1500

cccattgatg tttctgatct atcactttgc aaagctttca accaaaacca ccctgaaagc   1560

acagcagaat tcaatgattc tgactccggc atttcactaa acacaagtcc cagtgtggca   1620

tcaccagaac actcagtgga atcttccagc tatggagaca cactacttgg cctcagtgat   1680

tctgaagtgg aagagctaga tagtgcccct ggaagtgtca aacagaatgg tcctaaaaca   1740

ccagtacatt cttctgggga tatggtacaa cccttgtcac catctcaggg gcagagcact   1800

cacgtgcatg atgcccaatg tgagaacaca ccagagaaag aattgcctgt aagtcctggt   1860

catcggaaaa ccccattcac aaaagacaaa cattcaagcc gcttggaggc tcatctcaca   1920

agagatgaac ttagggcaaa agctctccat atcccattcc ctgtagaaaa aatcattaac   1980

ctccctgttg ttgacttcaa cgaaatgatg tccaaagagc agttcaatga agctcaactt   2040

gcattaattc gggatatacg taggaggggt aagaataaag tggctgctca gaattgcaga   2100

aaaagaaaac tggaaaatat agtagaacta gagcaagatt tagatcattt gaaagatgaa   2160

aaagaaaaat tgctcaaaga aaaaggagaa aatgacaaaa gccttcacct actgaaaaaa   2220

caactcagca ccttatatct cgaagttttc agcatgctac gtgatgaaga tggaaaacct   2280

tattctccta gtgaatactc cctgcagcaa acaagagatg gcaatgtttt ccttgttccc   2340

aaaagtaaga agccagatgt taagaaaaac tagatttagg aggatttgac cttttctgag   2400

ctagtttttt tgtactatta tactaaaagc tcctactgtg atgtgaaatg ctcatacttt   2460

ataagtaatt ctatgcaaaa tcatagccaa aactagtata gaaaataata cgaaacttta   2520

aaaagcattg gagtgtcagt atgttgaatc agtagtttca ctttaactgt aaacaatttc   2580

ttaggacacc atttgggcta gtttctgtgt aagtgtaaat actacaaaaa cttatttata   2640

ctgttcttat gtcatttgtt atattcatag atttatatga tgatatgaca tctggctaaa   2700

aagaaattat tgcaaaacta accactatgt acttttttat aaatactgta tggacaaaaa   2760

atggcatttt ttatattaaa ttgtttagct ctggcaaaaa aaaaaaattt taagagctgg   2820

tactaataaa ggattattat gactgttaaa ttattaaaa                          2859


<210>  694
<211>  2119
<212>  DNA
<213>  Human

<400>  694
ataggccccg cccctgtatc ccaagaccct gcctcctctt gcggtggggg gaaagcggcc     60

tcttactcta ggcctttcgg tttgcgcgag cgggcaggaa agcgtgcgtg cggctaagag    120

agtgggcgct ctcgcggccg ctgacgatgg aagaactgga gcaaggcctg ttgatgcagc    180

catgggcgtg gctacagctt gcagagaact ccctcttggc caaggttttt atcaccaagc    240

agggctatgc cttgttggtt tcagatcttc aacaggtgtg gcatgaacag gtggacacta    300

gtgtggtcag ccagcgagcc aaggagctga acaagcggct cactgctcct cctgcagctt    360

tcctctgtca tttggataat ctccttcgcc cattgttgaa ggacgctgct caccctagcg    420

aagctacctt ctcctgtgat tgtgtggcag atgcactgat tctacgggtg cgaagtgagc    480

tctctggcct ccccttctat tggaatttcc actgcatgct agctagtcct tccctggtct    540

cccaacattt gattcgtcct ctgatgggca tgagtctggc attacagtgc caagtgaggg    600

agctagcaac gttacttcat atgaaagacc tagagatcca agactaccag gagagtgggg    660

ctacgctgat tcgagatcga ttgaagacag aaccatttga agaaaattcc ttcttggaac    720

aatttatgat agagaaactg ccagaggcat gcagcattgg tgatggaaag ccctttgtca    780

tgaatctgca ggatctgtat atggcagtca ccacacaaga ggtccaagtg ggacagaagc    840

atcaaggcgc tggagatcct catacctcaa acagtgcttc cctgcaagga atcgatagcc    900

aatgtgtaaa ccagccagaa caactggtct cctcagcccc aaccctctca gcacctgaga    960

aagagtccac gggtacttca ggccctctgc agagacctca gctgtcaaag gtcaagagga   1020

agaagccaag gggtctcttc agttaatctg ttgtggcctc agctgctgag gatggacttg   1080

gagaacagct tccaagcttc accttgaaag aagcttacat ggcagcaata tttctaaaat   1140

agtgatacag tcagaggcct cctgtaaggg cgagagaact gaagttgatg ttgacaggcc   1200

cacagggaat tggccttccc tgttcaagtg gaagccagtc tctgagaatc ccgtgctctc   1260

ctctcttttg gtggaggttc tgtaggttca ggtttctacc atggacttta ggtatatagg   1320

gcaagtcagc aagaaagcac cacacactca ggaagccttg tctacctttc cctagcgtct   1380

ctagccagcc agccccagat actcctcaga gacccacttc tctcttttgc atggaataaa   1440

aagcactcac agtccctgct tttgggatta cttatgctgt ggaactcata acccaattca   1500

cttccttcac tgggtcccac cccattgttg tctctggatg aagtctagcc atcagtctgg   1560

tccttcagat tcttcgtaaa cttttctgca gttgccagag ctaagtctcc atttggaaac   1620

tttgatctca agaactctct tgatggtggg cacaagacag ataggtgatt gctgctttcc   1680

tttgccaaac ttggatgcat ttttctcttt gtttccaaag tataggcaac aggttaaact   1740

accacgtggg gtagtttatc aatcctcccg cctcatcctt ctgcataact gggactaaag   1800

gcacacacca ccacacctag ctaatttttg tatttttttg tgtgtggaga caaggctttg   1860

ccatgttgcc caggctggtc ttgaactcct ggactctagt gatctgccca cctcaacctc   1920

ccaaagtgct gggattacag gcatgagcta ccacgcctat ccaatttctg gtttatttac   1980

tttcgatggt taaatgcctc cttattcaaa tatcctgtat atatactggc gtttctgtcc   2040

tgatgtcaag tctcgagaga agatgatcaa acaataataa aataattata ataagaacaa   2100

caaaaaaaaa aaaaaaaaa                                                2119


<210>  695
<211>  5100
<212>  DNA
<213>  Human

<400>  695
cttgttgact aggcgctgtt cttgctggct ggtgccccag ggcctggaga ggtctgaaga     60

aacctgggag ccagcagccc ggggctccac tctgggttct gaaagcccat tccctgctct    120

gcggctcctc ccaccccacc tcttctcagc cttgcagctc aagggttgat ctcaggagtc    180

caggacccag gagagggaag aatctgagga acacagaaca gtgagcgttg cccacacccc    240

atctcccgtc accacatctc ccctcaccct caccctccct gcctggccct ggaccccatc    300

ccaggacctc cctatcagct gacttcttcc agtgtcttgc aggcccctct gggctcctcc    360

ctcccctggc ttttcctacc actccccctc tatcggcgtc tatctgtagg tgccctggga    420

tttataaaac tgggttccga atgctgaata agagacggta agagccaagg caaaggacag    480

cactgttctc tgcctgcctg ataccctcac cacctgggaa catcccccag acaccctctt    540

aactccggga cagagatggc tggcggagcc tggggccgcc tggcctgtta cttggagttc    600

ctgaagaagg aggagctgaa ggagttccag cttctgctcg ccaataaagc gcactccagg    660

agctcttcgg gtgagacacc cgctcagcca gagaagacga gtggcatgga ggtggcctcg    720

tacctggtgg ctcagtatgg ggagcagcgg gcctgggacc tagccctcca tacctgggag    780

cagatggggc tgaggtcact gtgcgcccaa gcccaggaag gggcaggcca ctctccctca    840

ttcccctaca gcccaagtga accccacctg gggtctccca gccaacccac ctccaccgca    900

gtgctaatgc cctggatcca tgaattgccg gcggggtgca cccagggctc agagagaagg    960

gttttgagac agctgcctga cacatctgga cgccgctgga gagaaatctc tgcctcactc   1020

ctctaccaag ctcttccaag ctccccagac catgagtctc caagccagga gtcacccaac   1080

gcccccacat ccacagcagt gctggggagc tggggatccc cacctcagcc cagcctagca   1140

cccagagagc aggaggctcc tgggacccaa tggcctctgg atgaaacgtc aggaatttac   1200

tacacagaaa tcagagaaag agagagagag aaatcagaga aaggcaggcc cccatgggca   1260

gcggtggtag gaacgccccc acaggcgcac accagcctac agccccacca ccacccatgg   1320

gagccttctg tgagagagag cctctgttcc acatggccct ggaaaaatga ggattttaac   1380

caaaaattca cacagctgct acttctacaa agacctcacc ccagaagcca agatcccctg   1440

gtcaagagaa gctggcctga ttatgtggag gagaatcgag gacatttaat tgagatcaga   1500

gacttatttg gcccaggcct ggatacccaa gaacctcgca tagtcatact gcagggggct   1560

gctggaattg ggaagtcaac actggccagg caggtgaagg aagcctgggg gagaggccag   1620

ctgtatgggg accgcttcca gcatgtcttc tacttcagct gcagagagct ggcccagtcc   1680

aaggtggtga gtctcgctga gctcatcgga aaagatggga cagccactcc ggctcccatt   1740

agacagatcc tgtctaggcc agagcggctg ctcttcatcc tcgatggtgt agatgagcca   1800

ggatgggtct tgcaggagcc gagttctgag ctctgtctgc actggagcca gccacagccg   1860

gcggatgcac tgctgggcag tttgctgggg aaaactatac ttcccgaggc atccttcctg   1920

atcacggctc ggaccacagc tctgcagaac ctcattcctt ctttggagca ggcacgttgg   1980

gtagaggtcc tggggttctc tgagtccagc aggaaggaat atttctacag atatttcaca   2040

gatgaaaggc aagcaattag agcctttagg ttggtcaaat caaacaaaga gctctgggcc   2100

ctgtgtcttg tgccctgggt gtcctggctg gcctgcactt gcctgatgca gcagatgaag   2160

cggaaggaaa aactcacact gacttccaag accaccacaa ccctctgtct acattacctt   2220

gcccaggctc tccaagctca gccattggga ccccagctca gagacctctg ctctctggct   2280

gctgagggca tctggcaaaa aaagaccctt ttcagtccag atgacctcag gaagcatggg   2340

ttagatgggg ccatcatctc caccttcttg aagatgggta ttcttcaaga gcaccccatc   2400

cctctgagct acagcttcat tcacctctgt ttccaagagt tctttgcagc aatgtcctat   2460

gtcttggagg atgagaaggg gagaggtaaa cattctaatt gcatcataga tttggaaaag   2520

acgctagaag catatggaat acatggcctg tttggggcat caaccacacg tttcctattg   2580

ggcctgttaa gtgatgaggg ggagagagag atggagaaca tctttcactg ccggctgtct   2640

caggggagga acctgatgca gtgggtcccg tccctgcagc tgctgctgca gccacactct   2700

ctggagtccc tccactgctt gtacgagact cggaacaaaa cgttcctgac acaagtgatg   2760

gcccatttcg aagaaatggg catgtgtgta gaaacagaca tggagctctt agtgtgcact   2820

ttctgcatta aattcagccg ccacgtgaag aagcttcagc tgattgaggg caggcagcac   2880

agatcaacat ggagccccac catggtagtc ctgttcaggt gggtcccagt cacagatgcc   2940

tattggcaga ttctcttctc cgtcctcaag gtcaccagaa acctgaagga gctggaccta   3000

agtggaaact cgctgagcca ctctgcagtg aagagtcttt gtaagaccct gagacgccct   3060

cgctgcctcc tggagaccct gcggttggct ggctgtggcc tcacagctga ggactgcaag   3120

gaccttgcct ttgggctgag agccaaccag accctgaccg agctggacct gagcttcaat   3180

gtgctcacgg atgctggagc caaacacctt tgccagagac tgagacagcc gagctgcaag   3240

ctacagcgac tgcagctggt cagctgtggc ctcacgtctg actgctgcca ggacctggcc   3300

tctgtgctta gtgccagccc cagcctgaag gagctagacc tgcagcagaa caacctggat   3360

gacgttggcg tgcgactgct ctgtgagggg ctcaggcatc ctgcctgcaa actcatacgc   3420

ctggggctgg accagacaac tctgagtgat gagatgaggc aggaactgag ggccctggag   3480

caggagaaac ctcagctgct catcttcagc agacggaaac caagtgtgat gacccctact   3540

gagggcctgg atacgggaga gatgagtaat agcacatcct cactcaagcg gcagagactc   3600

ggatcagaga gggcggcttc ccatgttgct caggctaatc tcaaactcct ggacgtgagc   3660

aagatcttcc caattgctga gattgcaggc aagagccacg aggaaagctc cccagaggta   3720

gtaccggtgg aactcttgtg cgtgccttct cctgcctctc aaggggacct gcatacgaag   3780

cctttgggga ctgacgatga cttctggggc cccacggggc ctgtggctac tgaggtagtt   3840

gacaaagaaa agaacttgta ccgagttcac ttccctgtag ctggctccta ccgctggccc   3900

aacacgggtc tctgctttgt gatgagagaa gcggtgaccg ttgagattga attctgtgtg   3960

tgggaccagt tcctgggtga gatcaaccca cagcacagct ggatggtggc agggcctctg   4020

ctggacatca aggctgagcc tggagctgtg gaagctgtgc acctccctca ctttgtggct   4080

ctccaagggg gccatgtgga cacatccctg ttccaaatgg cccactttaa agaggagggg   4140

atgctcctgg agaagccagc cagggtggag ctgcatcaca tagttctgga aaaccccagc   4200

ttctccccct tgggagtcct cctgaaaatg atccataatg ccctgcgctt cattcccgtc   4260

acctctgtgg tgttgcttta ccaccgcgtc catcctgagg aagtcacctt ccacctctac   4320

ctgatcccaa gtgactgctc cattcggaag gccatagatg atctagaaat gaaattccag   4380

tttgtgcgaa tccacaagcc acccccgctg accccacttt atatgggctg tcgttacact   4440

gtgtctgggt ctggttcagg gatgctggaa atactcccca aggaactgga gctctgctat   4500

cgaagccctg gagaagacca gctgttctcg gagttctacg ttggccactt gggatcaggg   4560

atcaggctgc aagtgaaaga caagaaagat gagactctgg tgtgggaggc cttggtgaaa   4620

ccaggaagga acaccagcca gccgtggaac ctcaggtgca acagagacgc caggagatac   4680

tagtgcccag cagcctgcgg cagtaccaat gaagccagag agggcttggt ggatgacaag   4740

gaggcctgag tagaccgcag gtgggtctga gaaatgggct taggtgaggc aggtctttga   4800

aggatttgtt cttaatcata tgcgagatgc tcaaaaggct ggatgcctgc ttttgtgggt   4860

gaagagcaag aagagaaaac aggttgtaca catacagatg cagatggaga gacagagaaa   4920

aaaaaggaag aaggcagaga aatgcaccaa ttcttgagct gtattatctc tggaccttgg   4980

gattgtggga ggctttattt tactactgat tttgcctaca ctgttttctc aatttctagt   5040

tttctacaaa gatgatgtgt tagctttttc acgcattaag attaaaattt aaaacagaaa   5100


<210>  696
<211>  3149
<212>  DNA
<213>  Human

<400>  696
cccagcccgg cctccgcccc tgcagccgcg ggcacgcgga ggggctcctg gctgcccgca     60

cctgcacccg cgcgtcggcg gcgccgaagc cccgctcccc gcctgcgcgt ctgtctcgtc    120

cgcatctccg cggcctcctg ctccacgacg tgaccatggc cgggctgcag gagctgcgat    180

tccctgagga gaagccgctg ctccggggcc aggacgccac cgagctggag agctccgatg    240

ccttcctctt ggctgcagac acagactgga aggaacatga catcgagaca ccctacggcc    300

ttctgcatgt agtgatccgg ggctccccca aggggaaccg cccagccatc ctcacctacc    360

atgatgtggg cctcaaccac aaactatgct tcaacacctt cttcaacttc gaggacatgc    420

aggagatcac caagcacttt gtggtgtgtc acgtggatgc ccctggacaa caggtggggg    480

cgtcgcagtt tcctcagggg taccagttcc cctccatgga gcagctggct gccatgctcc    540

ccagcgtggt gcagcatttc gggttcaagt atgtgattgg catcggagtg ggcgccggag    600

cctatgtgct ggccaagttt gcactcatct tccccgacct ggtggagggg ctggtgctgg    660

tgaacatcga ccccaatggc aaaggctgga tagactgggc tgccaccaag ctctccggcc    720

taactagcac tttacccgac acggtgctct cccacctctt cagccaggag gagctggtga    780

acaacacaga gttggtgcag agctaccggc agcagattgg gaacgtggtg aaccaggcca    840

acctgcagct cttctggaac atgtacaaca gccgcagaga cctggacatt aaccggcctg    900

gaacggtgcc caatgccaag acgctccgct gccccgtgat gctggtggtt ggggataatg    960

cacccgctga ggacggggtg gtggagtgca actccaaact ggacccgacc actacgacct   1020

tcctgaagat ggcagactct ggagggctgc cccaggtcac acagccaggg aagctgactg   1080

aagccttcaa atacttcctg caaggcatgg gctacattgc gtacttgaag gaccgaaggc   1140

tgagtggagg agcagtgccc tcagccagca tgacccgcct ggcacgctcc cgcactgcat   1200

ccctcaccag tgccagctcg gtggatggca gccgcccaca ggcctgcacc cactcagaga   1260

gcagcgaggg gctgggccag gtcaaccaca ccatggaggt gtcctgttga agcccttgat   1320

cccgctgacg acgcccacgt cgaggcccca ccgccatcct tgcgccggct catgttccct   1380

ttagtttatt tttgtgaggg caaaggggag gaaatggggt tctgtttgaa aaaaatgagg   1440

ggatcttaga tgctgcagca gaacagtctc caggtgtttt aaggggctca gtcctcctca   1500

tcccatctca ctctccgtgg taacttagcc aacttgaccc ctctcatccc actcccggcg   1560

gcccaggcac agaagggcag ggccataggg agggagattc gctacggatc caggccattc   1620

ctgggtgagc ccttgggcag gcatgtttgg agatgagaga ggcttcgaga gggtgggtgc   1680

tgggccacag gggtgcgggg ccagctcagg cactggcgtg ggagccctgg gagacccctt   1740

cccccaccct ccaccaagca cacctgtttc tgtctcatag cacatgtgac aatcatctgg   1800

acaacagcca caagggggcg ctcggaccag gcagccactt tcctggtgct ctctgggccc   1860

agctggtgct gtagggccac gcaggcaggg gcgtcaaggg gtttctctgc ccaaggaaga   1920

cagaacatgg agaaccgtca gggcaggaac cccacagact gtcccttcca gcccacactc   1980

tgccacctcc tggccctgtc ccaattctga gccaaggcct ccccgaggca gaagttgcct   2040

ggtcctctgt ccccacagtg acctgactgg gggtgaggga gaaggaggag agagcccatg   2100

tgtggtgtgt gtgcccctga gaacttcgtg gtgactgcct ttgggagccc gcaggtggcc   2160

agaggcaggg gtagctgagt tcctggagac cccttttttg cccccaggtt ccccagaggg   2220

caacgccatc agtagcagtg tggtgtttca ggcagagctc tggccaggct gtgccagtgt   2280

gtcccggacg catcactaag gaagagagag tttatttagt caactggccc aaggcagcga   2340

ggcttctaca gtcccacacc ccatagccgc ctgggctggg gcttactggg ggctgaaggt   2400

tctggacatg aacaagggtc aggtagaaga gaaaggcttc ccctacaccc cagcctcctg   2460

ctgtcccctg aagcccagga ctgcgttgta tgctttccat ccactcacct taccccatag   2520

catcttgcgg cccagaaacc agagccattt gtctcagacc ctaaatcaat aatcacaaac   2580

cccaaaacgg gagagagcag tgaaaacatg cagggctgtg gacgggggaa gggttgtggc   2640

gggtgttctg aggctgagag gacacctata tgcgtatttc ctctacacac atcacccccc   2700

ttctataatc ttaagccatg actagcctgg tggcgtgtta gtttctgccc agttctaccc   2760

cctcatgtgc ttcttctgaa tactgaatgt gactgtttga aagctggtag aattcatccc   2820

tcttactgta gataacactg caaatcttgg aattttgttt tttgctgttt ccagatgtat   2880

ctataaatat ctatacatta tatgtgtgtg tgtgtgtgtg tgtgtgtgtg tacatcgggt   2940

cctcccatgt gtggtgttct tctggaggtt gtctctttgg tcaaggtgaa cttttaatgt   3000

ttattatttt cttctccgca caaagtaaag agcctaattt tgtgtattct ggtggctgct   3060

gtcatgagat gataaaatgt aaaacaaaac tctagtcaac gtagaaagag ttaactgtgc   3120

tgaaaaacta ataaagaacc taagaagaa                                     3149


<210>  697
<211>  3114
<212>  DNA
<213>  Human

<400>  697
caggcgcagt gcaggactgc tccgagcacg cctacgcgcg cattttctcc ccttcctctc     60

cctctttcca ctttcctctc cctttttctc ctctcctttc cccctcccac cacttggtct    120

ttcagtcttt cagtcagttc gtttaggtct ctccttccga cccccacccc cagctcctct    180

ccctttcctt ttccccctcc ccctttcctt tcccgtctca cgcgccaggc cgcttgcaca    240

tgcgcattag gtacaaagcc tcgctctttg tccccatctg tcgttcacac gaactcaagc    300

ctttggcatt cggcagccaa tagaatctaa gaaatggcgg aaaaatgatt ccgcctcggg    360

agctaaacct tgattggcag tttagctaac caatcgagaa cgccattttg taccccttgg    420

caggcaccga gctccgtcgt ctcgtttccg gcggtcgcgc gctcttttct cgggacggga    480

gaggccgtgt agcgtcgccg ttactccgag gagataccag tcggtagagg agaagtcgag    540

gttagaggga actgggaggc actttgctgt ctgcaatcga agttgagggt gcaaaaatgc    600

agagtaataa aacttttaac ttggagaagc aaaaccatac tccaagaaag catcatcaac    660

atcaccacca gcagcagcac caccagcagc aacagcagca gccgccacca ccgccaatac    720

ctgcaaatgg gcaacaggcc agcagccaaa atgaaggctt gactattgac ctgaagaatt    780

ttagaaaacc aggagagaag accttcaccc aacgaagccg tctttttgtg ggaaatcttc    840

ctcccgacat cactgaggaa gaaatgagga aactatttga gaaatatgga aaggcaggcg    900

aagtcttcat tcataaggat aaaggatttg gctttatccg cttggaaacc cgaaccctag    960

cggagattgc caaagtggag ctggacaata tgccactccg tggaaagcag ctgcgtgtgc   1020

gctttgcctg ccatagtgca tcccttacag ttcgaaacct tcctcagtat gtgtccaacg   1080

aactgctgga agaagccttt tctgtgtttg gccaggtaga gagggctgta gtcattgtgg   1140

atgatcgagg aaggccctca ggaaaaggca ttgttgagtt ctcagggaag ccagctgctc   1200

ggaaagctct ggacagatgc agtgaaggct ccttcctgct aaccacattt cctcgtcctg   1260

tgactgtgga gcccatggac cagttagatg atgaagaggg acttccagag aagctggtta   1320

taaaaaacca gcaatttcac aaggaacgag agcagccacc cagatttgca cagcctggct   1380

cctttgagta tgaatatgcc atgcgctgga aggcactcat tgagatggag aagcagcagc   1440

aggaccaagt ggaccgcaac atcaaggagg ctcgtgagaa gctggagatg gagatggaag   1500

ctgcacgcca tgagcaccag gtcatgctaa tgagacagga tttgatgagg cgccaagaag   1560

aacttcggag gatggaagag ctgcacaacc aagaggtgca aaaacgaaag caactggagc   1620

tcaggcagga ggaagagcgc aggcgccgtg aagaagagat gcggcggcag caagaagaaa   1680

tgatgcggcg acagcaggaa ggattcaagg gaaccttccc tgatgcgaga gagcaggaga   1740

ttcggatggg tcagatggct atgggaggtg ctatgggcat aaacaacaga ggtgccatgc   1800

cccctgctcc tgtgccagct ggtaccccag ctcctccagg acctgccact atgatgccgg   1860

atggaacttt gggattgacc ccaccaacaa ctgaacgctt tggtcaggct gctacaatgg   1920

aaggaattgg ggcaattggt ggaactcctc ctgcattcaa ccgtgcagct cctggagctg   1980

aatttgcccc aaacaaacgt cgccgatact aataagttgc agtgtctagt ttctcaaaac   2040

ccttaaaaga aggacccttt ttggactagc cagaattcta ccctggaaaa gtgttaggga   2100

ttccttccaa tagttagatc taccctgcct gtactactct agggagtatg ctggaggcag   2160

agggcaaggg aggggtggta ttaaacaagt caattctgtg tggtatattg tttaatcagt   2220

tctgtgtggt gcattcctga agtctctaat gtgactgttg agggcctggg gaaaccatgg   2280

caaagtggat ccagttagag cccattaatc ttgatcattc cggttttttt tttttttgtc   2340

catcttgttt catttgcttg ccccgccccc gagacggagt cttactctgt cgcccaggct   2400

ggagtgtagt ggcatgatct cggctcactg caatctctgc ctcccgggtt caagcttgtc   2460

caggttgatc ttgaactcct gacctcgtga tctacccacc tcggcctccc aaaatgctgg   2520

gattacaggg gtgagccacc gtgcccaacc tcacttgctt cttatcctta cactccccca   2580

gccccagaga aactgccaca tacaccacaa aaaccaaaca tcccccaatg accttagccc   2640

cattgctcca ttcactccca ggtgagaatt caggcaaacg tccacaaagg tcacaggcag   2700

cgtacatacg gttctgttat accccatata ttaccccttc atgtcctaaa gaagacattt   2760

tctcttagag attttcattt tagtgtatct ttaaaaaaaa atcttgtgtt aacttgcctc   2820

catctttttc ttgggtgagg acacccagga atgacccttt tgtgtctatg atgttgctgt   2880

tcacagcttt tcttgatagg cctagtacaa tcttgggaac agggttactg tatactgaag   2940

gtctgacagt agctcttaga ctcgcctatc ttaggtagtc atgctgtgca tttttttttt   3000

cattggtgta ctgtgtttga tttgtctcat atatttggag tttttctgaa aaatggagca   3060

gtaatgcagc atcaacctat taaaatacat tttaagcctt ttaaaaaaaa aaaa         3114


<210>  698
<211>  1916
<212>  DNA
<213>  Human

<400>  698
atggcgccgt gcgtggcctc ggcggtggcg cagggggcgg gcccgcggcg cggcgccgga     60

ggaggaagtg gtgaggttgt tgctccttca gcgcctatcg ctggctcttg gggcgcagag    120

aggggccgca gtctccgcgg ctgcgtcgag ctcccttgca gtcccctcca tgttccccgg    180

cgccactact ccccttccta aggccgccgc ttaccccggg gtctatggaa gtaatggaag    240

gacccctcaa cctggctcat caacagagca gacgagcaga ccgtttatta gctgcaggca    300

aatacgaaga ggctatttct tgtcacaaaa aggctgcagc atatctttct gaagccatga    360

agctgacaca gtcagagcag gctcatcttt cactggaatt gcaaagggat agccatatga    420

aacagctcct cctcatccaa gagagatgga aaagggccca gcgtgaagaa agattgaaag    480

cccagcagaa cacagacaag gatgcagctg cccatcttca gacatctcac aaaccctctg    540

cagaggatgc agagggccag agtccccttt ctcagaagta cagcccttcc acagagaaat    600

gcctgcctga gattcagggg atctttgaca gggatccaga cacactactt tatttacttc    660

agcaaaagag tgagccagca gagccatgta ttggaagcaa agccccaaaa gatgataaaa    720

caattataga ggagcaggca accaaaattg cagatttgaa gaggcatgtg gaattccttg    780

tggctgagaa tgaaagatta aggaaagaaa ataaacaact aaaggctgaa aaggccagac    840

ttctaaaagg tccaatagaa aaggagctgg atgtagatgc tgattttgta gaaacgtcag    900

agttatggag cttgccacca catgcagaaa ctgctacagc ctcctcaacc tggcagaagt    960

tcgcagcaaa tactgggaaa gccaaggaca ttccaatccc caatcttcct cccttggatt   1020

ttccatctcc agaacttcct cttatggagc tctctgagga tattctgaaa ggatttatga   1080

ataattaaaa tggaaggcca cagaaaaggg gaaaagagga aataatacag taatcgttaa   1140

tccagcaaaa agaaatgaaa agggaaaacc acatagaagg gtaatcccgg aaatgcttca   1200

tctggtggac tgtgggagca gaggcattgc caggacttgg gaaacagtca ctgtgaaatg   1260

cgctgcgtat ctcattcact cacttcagct aatgattccg acttggcaga cgctaaactc   1320

atggaggttc ggtttctcct gatacaaacc aaatggctac ctggaagaat ttctttcaag   1380

caacagttat ttttcttatc ttcagggtta aaatgtataa aagttatgtg taattaatct   1440

ataatgccat aaatgataat gcaaaaccta aataatatgg tggccggagg ggctgcctta   1500

tatttgaaac atgctttcta tcatgcattg actgtatgca ttttgttaat gcacattctg   1560

tttgtttaag gtgtgtaaga tacacaccct tctagatgaa actatatgtg ccacactttg   1620

cactactcat aatgataacc tcaagactat cagaagaaat atttaaattt ccattttatg   1680

aagaaaggaa ccaaattatt atgcttttta aaacaaatta ccagtttaca taattaatca   1740

gggtgcattt taagttctaa cttcgtttat tgtataatgc atcatttgaa aataccaagg   1800

aggaaatacc ctttgttttt aatgatgcaa gagtggacgt aatgctagtt ggcagtattt   1860

tattgtaaga aatcaataaa gtaattgtgt tttataaaaa aaaaaaaaaa aaaaaa       1916


<210>  699
<211>  3582
<212>  DNA
<213>  Human

<400>  699
gccggagtcc ccacgcgagg atgctgcggt gagcgcggcc gggacgccgc gtcgggctct     60

cggccgccca gcggcgccgc aggggaagcc aggccggcag ccgcgcgctc cccagccggc    120

caccaatccc gccctccccg gctcctccgg acctcctcgg caggcggcgg cggggcctgc    180

ctgtgcgctc tgcgcccgcc cgcgcctacc ctccatggcg tttatccgga agaagcagca    240

ggagcagcag ctgcagctct actccaagga gagattttcc ttgctgctgc ttaacttgga    300

ggagtactac tttgaacagc atagagccaa tcacattttg cacaagggca gtcaccatga    360

aaggaaaatc agaggctcct taaaaatatg ttcaaaatcg gtgatttttg aaccagattc    420

aatatcccag cccatcatca agattccttt gagagactgt ataaaaatag gaaagcatgg    480

agaaaatgga gccaatagac acttcacaaa ggcaaaatct gggggtattt cactcatttt    540

cagtcaggta tatttcatta aagaacataa tgttgttgca ccatataaaa tagaaagggg    600

caaaatggaa tatgtttttg aattggatgt tcccgggaaa gtggaagatg ttgtggagac    660

gttgcttcag cttcacagag catcctgcct tgacaaattg ggtgaccaaa ccgccatgat    720

aacagctatt ttgcagtctc gtttagctag aacatcattt gacaaaaaca ggttccaaaa    780

catttctgaa aagctgcaca tggaatgcaa agcagaaatg gtgacgcctc tggtgactaa    840

tcctggacac gtgtgcatca cggacacaaa cctgtatttt cagcccctca acggctaccc    900

gaaacctgtg gtccagataa cactccaaga tgtccgccgc atctacaaaa ggaggcacgg    960

cctcatgcct ctgggcttgg aagtattttg cacagaagat gatctgtgtt ccgacatcta   1020

cctaaagttc tatgaacctc aagatagaga tgatctctat ttttacattg ccacatacct   1080

agagcaccat gtggcggagc acactgctga gagctacatg ctgcagtggc agcgtggaca   1140

cctttccaac tatcagtacc tccttcacct caacaacctg gccgaccgca gctgcaacga   1200

cctctcccag taccctgtgt ttccatggat aatacatgat tattccagct cagaactaga   1260

tttgtcaaat ccaggaacct tccgggatct cagtaagcca gtaggggccc taaataagga   1320

acggctggag agactactga cacgctacca ggaaatgcct gaaccaaagt tcatgtatgg   1380

gagtcactac tcttccccgg gttatgtact tttttatctt gttaggattg caccagagta   1440

tatgctgtgc ctgcagaatg gaagatttga taatgcagat agaatgttca acagtattgc   1500

agaaacttgg aaaaactgtc tggatggtgc aacggatttt aaagagttaa ttccagaatt   1560

ctatggtgat gatgtgagct ttctagtcaa tagcctgaag ttggatttgg gaaagagaca   1620

aggaggacag atggttgacg acgtggagct tcccccttgg gcttccagtc ccgaggactt   1680

tctccagaag agcaaagatg cattggaaag caattatgtg tctgaacacc ttcacgagtg   1740

gattgatcta atatttggct acaaacaaaa agggagtgat gcagttgggg cccataatgt   1800

atttcatccc ctgacctatg aaggaggtgt agacttgaac agcatccagg atcctgatga   1860

gaaggtagcc atgcttacgc aaatcttgga atttgggcag acaccaaaac aactatttgt   1920

gacaccacat cctcgaagga tcaccccaaa gtttaaaagt ttgtcccaga cctccagtta   1980

taatgcttct atggcagatt ccccaggtga agagtctttt gaagacctga ccgaagaaag   2040

caaaacactg gcctggaata acatcaccaa actgcagtta cacgagcact ataaaatcca   2100

caaagaagca gttactggaa tcacggtctc tcgcaatgga tcttcagtat tcacaacatc   2160

ccaagattcc accttgaaga tgttttctaa agaatcaaaa atgctacaaa gaagtatatc   2220

attttcaaat atggctttat cgtcttgttt acttttacca ggagatgcca ctgtcataac   2280

ttcttcatgg gataataatg tctattttta ttccatagca tttggaagac gccaggacac   2340

gttaatggga catgatgatg ctgttagtaa gatctgttgg catgacaaca ggctatattc   2400

tgcatcgtgg gactctacag tgaaggtgtg gtctggtgtt cctgcagaga tgccaggcac   2460

caaaagacac cactttgact tgctggccga gctggaacat gatgtcagtg tagatacaat   2520

cagtttaaat gctgcaagca cactgttagt ttccggcacc aaagaaggca cagtgaatat   2580

ttgggacctc acaacggcca ccttaatgca ccagattcca tgccattcag ggattgtatg   2640

tgacactgct tttagcccag atagtcgcca tgtcctcagc acaggaacag atggctgtct   2700

taatgtcatt gatgtgcaga caggaatgct catctcctcc atgacatcag atgagcccca   2760

gaggtgcttt gtctgggatg gaaattccgt tttatctggc agtcagtctg gtgaactgct   2820

cgtttgggac ctccttggag caaaaatcag tgagagaata cagggccaca caggtgctgt   2880

gacatgtata tggatgaatg aacagtgtag cagtatcatc acaggagggg aagacagaca   2940

aattatattc tggaaattgc agtattaagt gccttttcct ctcctgaata ttaaattgaa   3000

ctctatttaa tgcattttta aaccaaactt ttaaacggac tggtgaatgt gcaatgttag   3060

taattagaag ttttaccaca tggaaaattt gtggttttaa actttctaaa tcatggtgac   3120

ttcattgaaa gccattagtt gctattctct tagggcagat aaaatgcggc tgtgttagga   3180

aaaacatgtt acactgtaag gcagatgatc gtccccgtat gatgattgtc agaagacagg   3240

actaagtagc agagaatagc taagagataa attgggctgg ggaaacttgt cagaaagcac   3300

tgaacaatta agaaattttc caagaaaatg tgcagtattc tctgctactt ctgaatctgt   3360

tttgtcttcc taatctatca caattgccac ccatcgggtt ttgggtgtgt gttttcatag   3420

cgtggttact ttctataatg ctgtacccag attctaagaa cctggagaag gattagcagt   3480

tcttagtaag tttactgtgt ataggaacgg tttgtatttc attacagcta ttcatctttt   3540

ctacattaaa aatatttttc tctaaagaaa aaaaaaaaaa aa                      3582


<210>  700
<211>  7182
<212>  DNA
<213>  Human

<400>  700
gcgctggcgc gagcccacga agaggtacga ttccggagaa tcgcgaggca gagcgggagc     60

gcgcagccag gtggaaacta attctaagcc agactgctgg agatcaccct gttctagtgt    120

gtggaggctt ccaccaggag gcgcattgga gtgactgtct ggcatcacca agatgacact    180

ccacgccacc cggggggctg cactcctctc ttgggtgaac agtctacacg tggctgaccc    240

tgtggaggct gtgctgcagc tccaggactg cagcatcttc atcaagatca ttgacagaat    300

ccatggcact gaagagggac agcaaatctt gaagcagccg gtgtcagaga gactggactt    360

tgtgtgcagt tttctgcaga aaaatcgaaa acatccctct tccccagaat gcctggtatc    420

tgcacagaag gtgctagagg gatcagagct ggaactggcg aagatgacca tgctgctctt    480

ataccactct accatgagct ccaaaagtcc cagggactgg gaacagtttg aatataaaat    540

tcaggctgag ttggctgtca ttcttaaatt tgtgctggac catgaggacg ggctaaacct    600

taatgaggac ctagagaact tcctacagaa agctcctgtg ccttctacct gttctagcac    660

attccctgaa gagctctccc cacctagcca ccaggccaag agggagattc gcttcctaga    720

gctacagaag gttgcctcct cttccagtgg gaacaacttt ctctcaggtt ctccagcttc    780

tcccatgggt gatatcctgc agaccccaca gttccagatg agacggctga agaagcagct    840

tgctgatgag agaagtaata gggatgagct ggagctggag ctagctgaga accgcaagct    900

cctcaccgag aaggatgcac agatagccat gatgcagcag cgcattgacc gcctagccct    960

gctgaatgag aagcaggcgg ccagcccact ggagcccaag gagcttgagg agctgcgtga   1020

caagaatgag agccttacca tgcggctgca tgaaaccctg aagcagtgcc aggacctgaa   1080

gacagagaag agccagatgg atcgcaaaat caaccagctt tcggaggaga atggagacct   1140

ttcctttaag ctgcgggagt ttgccagtca tctgcagcag ctacaggatg ccctcaatga   1200

gctgacggag gagcacagca aggccactca ggagtggcta gagaagcagg cccagctgga   1260

gaaggagctc agcgcagccc tgcaggacaa gaaatgcctt gaagagaaga acgaaatcct   1320

tcagggaaaa ctttcacagc tggaagaaca cttgtcccag ctgcaggata acccacccca   1380

ggagaagggc gaggtgctgg gtgatgtctt gcagctggaa accttgaagc aagaggcagc   1440

cactcttgct gcaaacaaca cacagctcca agccagggta gagatgctgg agactgagcg   1500

aggccagcag gaagccaagc tgcttgctga gcggggccac ttcgaagaag aaaagcagca   1560

gctgtctagc ctgatcactg acctgcagag ctccatctcc aacctcagcc aggccaagga   1620

agagctggag caggcctccc aggctcatgg ggcccggttg actgcccagg tggcctctct   1680

gacctctgag ctcaccacac tcaatgccac catccagcaa caggatcaag aactggctgg   1740

cctgaagcag caggccaaag agaagcaggc ccagctagca cagaccctcc aacagcaaga   1800

acaggcctcc cagggcctcc gccaccaggt ggagcagcta agcagtagcc tgaagcagaa   1860

ggagcagcag ttgaaggagg tagcggagaa gcaggaggca actaggcagg accatgccca   1920

gcaactggcc actgctgcag aggagcgaga ggcctcctta agggagcggg atgcggctct   1980

caagcagctg gaggcactgg agaaggagaa ggctgccaag ctggagattc tgcagcagca   2040

acttcaggtg gctaatgaag cccgggacag tgcccagacc tcagtgacac aggcccagcg   2100

ggagaaggca gagctgagcc ggaaggtgga ggaactccag gcctgtgttg agacagcccg   2160

ccaggaacag catgaggccc aggcccaggt tgcagagcta gagttgcagc tgcggtctga   2220

gcagcaaaaa gcaactgaga aagaaagggt ggcccaggag aaggaccagc tccaggagca   2280

gctccaggcc ctcaaagagt ccttgaaggt caccaagggc agccttgaag aggagaagcg   2340

cagggctgca gatgccctgg aagagcagca gcgttgtatc tctgagctga aggcagagac   2400

ccgaagcctg gtggagcagc ataagcggga acgaaaggag ctggaagaag agagggctgg   2460

gcgcaagggg ctggaggctc gattacagca gcttggggag gcccatcagg ctgagactga   2520

agtcctgcgg cgggagctgg cagaggccat ggctgcccag cacacagctg agagtgagtg   2580

tgagcagctc gtcaaagaag tagctgcctg gcgtgagcgg tatgaggata gccagcaaga   2640

ggaggcacag tatggcgcca tgttccagga acagctgatg actttgaagg aggaatgtga   2700

gaaggcccgc caggagctgc aggaggcaaa ggagaaggtg gcaggcatag aatcccacag   2760

cgagctccag ataagccggc agcagaacga actagctgag ctccatgcca acctggccag   2820

agcactccag caggtccaag agaaggaagt cagggcccag aagcttgcag atgacctctc   2880

cactctgcag gaaaagatgg ctgccaccag caaagaggtg gcccgcttgg agaccttggt   2940

gcgcaaggca ggtgagcagc aggaaacagc ctcccgggag ttagtcaagg agcctgcgag   3000

ggcaggagac agacagcccg agtggctgga agagcaacag ggacgccagt tctgcagcac   3060

acaggcagcg ctgcaggcta tggagcggga ggcagagcag atgggcaatg agctggaacg   3120

gctgcgggcc gcgctgatgg agagccaggg gcagcagcag gaggagcgtg ggcagcagga   3180

aagggaggtg gcgcggctga cccaggagcg gggccgtgcc caggctgacc ttgccctgga   3240

gaaggcggcc agagcagagc ttgagatgcg gctgcagaac gccctcaacg agcagcgtgt   3300

ggagttcgct accctgcaag aggcactggc tcatgccctg acggaaaagg aaggcaagga   3360

ccaggagttg gccaagcttc gtggtctgga ggcagcccag ataaaagagc tggaggaact   3420

tcggcaaacc gtgaagcaac tgaaggaaca gctggctaag aaagaaaagg agcacgcatc   3480

tggctcagga gcccaatctg aggctgctgg caggacagag ccaacaggcc ccaagctgga   3540

ggcactgcgg gcagaggtga gcaagctgga acagcaatgc cagaagcagc aggagcaggc   3600

tgacagcctg gaacgcagcc tcgaggctga gcgggcctcc cgggctgagc gggacagtgc   3660

tctggagact ctgcagggcc agttagagga gaaggcccag gagctagggc acagtcagag   3720

tgccttagcc tcggcccaac gggagttggc tgccttccgc accaaggtac aagaccacag   3780

caaggctgaa gatgagtgga aggcccaggt ggcccggggc cggcaagagg ctgagaggaa   3840

aaatagcctc atcagcagct tggaggagga ggtgtccatc ctgaatcgcc aggtcctgga   3900

gaaggagggg gagagcaagg agttgaagcg gctggtgatg gccgagtcag agaagagcca   3960

gaagctggag gagaggctgc gcctgctgca ggcagagaca gccagcaaca gtgccagagc   4020

tgcagaacgc agctctgctc tgcgggagga ggtgcagagc ctccgggagg aggctgagaa   4080

acagcgggtg gcttcagaga acctgcggca ggagctgacc tcacaggctg agcgtgcgga   4140

ggagctgggc caagaattga aggcgtggca ggagaagttc ttccagaaag agcaggccct   4200

ctccaccctg cagctcgagc acaccagcac acaggccctg gtgagtgagc tgctgccagc   4260

taagcacctc tgccagcagc tgcaggccga gcaggccgct gccgagaaac gccaccgtga   4320

ggagctggag cagagcaagc aggccgctgg gggactgcgg gcagagctgc tgcgggccca   4380

gcgggagctt ggggagctga ttcctctgcg gcagaaggtg gcagagcagg agcgaacagc   4440

tcagcagctg cgggcagaga aggccagcta tgcagagcag ctgagcatgc tgaagaaggc   4500

gcatggcctg ctggcagagg agaaccgggg gctgggtgag cgggccaacc ttggccggca   4560

gtttctggaa gtggagttgg accaggcccg ggagaagtat gtccaagagt tggcagccgt   4620

acgtgctgat gctgagaccc gtctggctga ggtgcagcga gaagcacaga gcactgcccg   4680

ggagctggag gtgatgactg ccaagtatga gggtgccaag gtcaaggtcc tggaggagag   4740

gcagcggttc caggaagaga ggcagaaact cactgcccag gtggagcagc tagaggtatt   4800

tcagagagag caaactaagc aggtggaaga actgagtaag aaactggctg actctgacca   4860

agccagcaag gtgcagcagc agaagctgaa ggctgtccag gctcagggag gcgagagcca   4920

gcaggaggcc cagcgcctcc aggcccagct gaatgaactg caagcccagt tgagccagaa   4980

ggagcaggca gctgagcact ataagctgca gatggagaaa gccaaaacac attatgatgc   5040

caagaagcag cagaaccaag agctgcagga gcagctgcgg agcctggagc agctgcagaa   5100

ggaaaacaaa gagctgcgag ctgaagctga acggctgggc catgagctac agcaggctgg   5160

gctgaagacc aaggaggctg aacagacctg ccgccacctt actgcccagg tgcgcagcct   5220

ggaggcacag gttgcccatg cagaccagca gcttcgagac ctgggcaaat tccaggtggc   5280

aactgatgct ttaaagagcc gtgagcccca ggctaagccc cagctggact tgagtattga   5340

cagcctggat ctgagctgcg aggaggggac cccactcagt atcaccagca agctgcctcg   5400

tacccagcca gacggcacca gcgtccctgg agaaccagcc tcacctatct cccagcgcct   5460

gccccccaag gtagaatccc tggagagtct ctacttcact cccatccctg ctcggagtca   5520

ggcccccctg gagagcagcc tggactccct gggagacgtc ttcctggact cgggtcgtaa   5580

gacccgctcc gctcgtcggc gcaccacgca gatcatcaac atcaccatga ccaagaagct   5640

agatgtggaa gagccagaca gcgccaactc atcgttctac agcacgcggt ctgctcctgc   5700

ttcccaggct agcctgcgag ccacctcctc tactcagtct ctagctcgcc tgggttctcc   5760

cgattatggc aactcagccc tgctcagctt gcctggctac cgccccacca ctcgcagttc   5820

tgctcgtcgt tcccaggccg gggtgtccag tggggcccct ccaggaagga acagcttcta   5880

catgggcact tgccaggatg agcctgagca gctggatgac tggaaccgca ttgcagagct   5940

gcagcagcgc aatcgagtgt gccccccaca tctgaagacc tgctatcccc tggagtccag   6000

gccttccctg agcctgggca ccatcacaga tgaggagatg aaaactggag acccccaaga   6060

gaccctgcgc cgagccagca tgcagccaat ccagatagcc gagggcactg gcatcaccac   6120

ccggcagcag cgcaaacggg tctccctaga gccccaccag ggccctggaa ctcctgagtc   6180

taagaaggcc accagctgtt tcccacgccc catgactccc cgagaccgac atgaagggcg   6240

caaacagagc actactgagg cccagaagaa agcagctcca gcttctacta aacaggctga   6300

ccggcgccag tcgatggcct tcagcatcct caacacaccc aagaagctag ggaacagcct   6360

tctgcggcgg ggagcctcaa agaaggccct gtccaaggct tcccccaaca ctcgcagtgg   6420

aacccgccgt tctccgcgca ttgccaccac cacagccagc gccgccactg ctgccgccat   6480

tggtgccacc cctcgagcca agggcaaggc aaagcactaa agggccagta ccagtgagtg   6540

gccccacctg tgtccccgat gctgacctca cctggtcctc cgcctactgt ccctctcagt   6600

gccttctctc agctcccagg ccaacagtag ccaaacccct agagacagtg atgcctgccc   6660

gcaccctggc ctggtccctg gtccttcact ggcgccttct cggagctggc ccagggggcc   6720

tggagcatgg acagtgtggg cgctctccct accttgcctc cttttttctt aaagcaaagt   6780

cacttctcca tcacaaccag atttgaggct ggttttgatg gctgggtcct tgggcctggc   6840

cagtcttcct cttagcctct ggatctagaa gggaccataa gaggagtagg ccctggttcc   6900

tgctgtcctg gtggctgggc ccagcagggg ccctcactct tgaagtccag gactgggtct   6960

gacctggtgg gagcacctgc cagaggatgc tctttcccag gacggatggg ccctatgtct   7020

caggagtggg gttgggggac agccttcagc agcagctcac accctacctt ccccagactt   7080

gcactggggt gggatttgga gtgatgggaa ggtttttaag ggccggggat ggatcttttc   7140

taaatgttat tacttgtaaa taaagtctat ttttctcccg tg                      7182


<210>  701
<211>  939
<212>  DNA
<213>  Human

<400>  701
gtggccggct gggatcagcc tttaagatgg cgtctcctca ggggggccag attgcgatcg     60

cgatgaggct tcggaaccag ctccagtcag tgtacaagat ggacccgcta cggaacgagg    120

aggaggttcg agtgaagatc aaagacttga atgaacacat tgtttgctgc ctatgcgccg    180

gctacttcgt ggatgccacc accatcacag agtgtcttca tactttctgc aagagttgta    240

ttgtgaagta cctccaaact agcaagtact gccccatgtg caacattaag atccacgaga    300

cacagccact gctcaacctc aaactggacc gggtcatgca ggacatcgtg tataagctgg    360

tgcctggctt gcaagacagt gaagagaaac ggattcggga attctaccag tcccgaggtt    420

tggaccgggt cacccagccc actggggaag agccagcact gagcaacctc ggcctcccct    480

tcagcagctt tgaccactct aaagcccact actatcgcta tgatgagcag ttgaacctgt    540

gcctggagcg gctgagttct ggcaaagaca agaataaaag cgtcctgcag aacaagtatg    600

tccgatgttc tgttagagct gaggtacgcc atctccggag ggtcctgtgt caccgcttga    660

tgctaaaccc tcagcatgtg cagctccttt ttgacaatga agttctccct gatcacatga    720

caatgaagca gatatggctc tcccgctggt tcggcaagcc atcccctttg cttttacaat    780

acagtgtgaa agagaagagg aggtaggggc caagccccca ccccatccca ctccccttcc    840

ctccccagat atttatgtga aatgaactgc agctttattt tttgaaataa aaacttttaa    900

aaagcaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa                           939


<210>  702
<211>  1174
<212>  DNA
<213>  Human

<400>  702
tagtttgcgt tttcacctgg tcgcccggcg gccatggcgg ccgttctgaa gccggtgctg     60

ctgggccttc gagatgcgcc ggtgcacggc agccccacag ggccgggtgc ctggactgct    120

agcaagctgg gcggcattcc ggatgctctg cccaccgtgg ctgcgcccag gcccgtgtgt    180

cagcgctgcg ggcagccgct cgctctggtc gtgcaggtgt attgcccgct ggaaggctcc    240

ccgtttcacc gtctgctgca cgtgttcgcg tgcgcctgcc ccggctgtag caccggcggt    300

gcgcgcagct ggaaggtgtt ccgctcccag tgcctgcagg tgccagagag agaggcgcag    360

gacgctcaga aacagggaaa cagccttgca gctgaggact ggtgtgaagg tgctgatgac    420

tggggaagtg atactgagga ggggccttca ccacagttta ccttggattt tgggaatgat    480

gccagcagtg ccaaagacgt agactggact gctcggctcc aagacctccg cctgcaggat    540

gctgtcctgg gtgctgccca tcctgtgcct cctgggctgc cgctcttcct gccctactac    600

atctgtgttg cagatgagga tgattacagg gactttgtca acctggatca tgcccacagc    660

cttctgaggg actatcagca gagagaaggc attgccatgg atcagttgct ttcccaaagc    720

cttcctaatg atggtgatga aaaatatgag aagaccataa ttaaaagtgg agatcagacg    780

ttttacaaat tcatgaagcg aattgctgct tgtcaggagc agattttgag gtattcctgg    840

agtggagagc cactcttttt gacctgccct acatcagaag tcaccgagct cccagcctgc    900

agccagtgtg gaggccaaag gatatttgag tttcagctta tgccagcact ggtcagcatg    960

ctcaagagtg ctaatttagg tctttctgtg gaatttggaa caattctagt ttacacatgt   1020

gagaagagtt gctggccccc aaatcatcag actcccatgg aagaattttg tattatacaa   1080

gaagacccag atgaattatt gtttaagtag agcatttcct tttattaata taaattaaaa   1140

caaatgttta catccaaaaa aaaaaaaaaa aaaa                               1174


<210>  703
<211>  1945
<212>  DNA
<213>  Human

<400>  703
gattagtcag gcctcagaaa gatggcgtcc tcggagcagg cagagcagcc gagccagcca     60

agctctactc caggaagtga aaatgtgctg cctcgagagc cgctgattgc cacggcagtg    120

aagtttctac agaattcccg ggtccgccag agcccacttg caaccaggag agcattccta    180

aagaagaaag ggctgacaga tgaagagatt gatatggcct tccagcagtc gggcactgct    240

gccgatgagc cttcgtcctt gggcccagcc acacaggtgg ttcctgtcca gccccctcac    300

ctcatatctc agccatacag tcccgcaggc tcccgatggc gagattacgg cgccctggcc    360

atcatcatgg caggcattgc atttggcttt caccagctct acaagaaata cctgctcccc    420

ctcatcctgg gcggccgaga ggacagaaag cagctggaga ggatggaggc cggtctctct    480

gagctgagtg gcagcgtggc ccagacagtg actcagttac agacgaccct cgcctccgtc    540

caggagctgc tgattcagca gcagcagaag atccaggagc ttgcccacga gctggccgct    600

gccaaggcca ccacatccac caactggatc ctggagtccc agaatatcaa cgaactcaag    660

tccgaaatta actccttgaa agggcttctt ttaaatcgga ggcagttccc tccatcccca    720

tcagccccga agatcccctc ctggcagatc ccagtcaagt caccgtcacc ctccagccct    780

gcggccgtga accaccacag cagcagcgac atctcacctg tcagcaacga gtccacgtcg    840

tcctcgcctg ggaaggaggg ccacagcccc gagggctcca cggtcaccta ccacttgctg    900

ggcccccagg aggaaggcga gggggtggtg gacgtcaagg gccaggtgcg gatggaggtg    960

caaggcgagg aggagaagag ggaggacaag gaggacgagg aggatgagga ggatgatgat   1020

gtgagccatg tggacgagga ggactgcctg ggggtgcaga gggaggaccg ccggggcggg   1080

gatgggcaga tcaacgagca ggtggagaag ctgcggcggc ccgagggcgc cagcaacgag   1140

agtgagcggg actagggctg cgcctgctgc ctccagccct gaggatggca tctagtgtgc   1200

ccgtgcgtgg ccataccctg cctccctctc tggccctggg agggcagctt ggagcccagg   1260

tagggggcag agctgtcctc agctgcactg cggcctggtg gcagtgtggg gagtcacact   1320

tctgtccacc tggcctcctc tcgcctggcc gccagcccca gccccagccc cagccccagg   1380

cccagctgcc tttggctttg atctcaagtc aggctgaagg cagcgaagcc tcggggccca   1440

agcccctccc cagccccctc tcccggacag acgccttgcc cagggtgtgt ttgctgagtg   1500

tcttgactac cgtgacacca cgcatggcca gagctagcgt ccctactgcc tcccgactcc   1560

tcagtggagg aggagctgcg gtccctctgg tgtctgccat ccccctccct ccctgggccc   1620

ggccctggac ccgtcaggtg cctgtcccca gccccaaccc cactcatgcc ccgtcgtcct   1680

cccagacaaa tgaaaccacg ctgcgcttcc gatgcccccg cttgccgtgt aatggttcag   1740

ctaatcccat ggcgagatgg gggctcactc cggaggagga gccaggcagc agggccttcc   1800

tgaccaacag ccagctctgt ccttcccccc aggaaacaca tgttcatttg tgtgatcatg   1860

tatagacctc agaacggaag ataggactgt atataattgt aataaatacc agttgccact   1920

atttaaaaaa aaaaaaaaaa aaaaa                                         1945


<210>  704
<211>  2993
<212>  DNA
<213>  Human

<400>  704
ggaagtgggg ctcgggtccc gcggcggggc tggaggcagc gagcgccgtc gtctgcccgg     60

gcccgcccat cggggtcccc aaccccatcc ggaccccgcc gcccgagcgc gcggccccgg    120

aagcacccgc ctcccggcat ggtgctcaag gccttcttcc ccacgtgctg cgtctcgacg    180

gacagcgggc tgctggtggg acggtgggtg ccggagcaga gcagcgccgt ggtcctggcg    240

gtcctgcact ttcccttcat ccccatccag gtcaagcagc tcctggccca ggtgcggcag    300

gccagccagg tgggcgtggc cgtgctgggc acctggtgcc actgccggca ggagcccgag    360

gagagcctgg gccgcttcct ggagagcctg ggtgctgtct tcccccatga gccctggctg    420

cggctgtgcc gggagagagg cggcacgttc tggagctgcg aggccaccca ccggcaagcg    480

cccactgccc ccggtgcccc tggtgaggac caggtcatgc tcatcttcta tgaccagcgc    540

caggtgttgc tgtcacagct acacctgccc accgtcctgc ccgaccgcca ggctggagcc    600

accactgcca gcacgggggg cctggctgcc gtcttcgaca cggtagcacg cagtgaggtg    660

ctcttccgca gtgaccgctt tgatgagggc cccgtgcggc tgagccactg gcagtcggag    720

ggcgtggagg ccagcatcct cgcggagctg gccaggcgag cctcgggacc catttgcctg    780

ctgttggcca gcctgctgtc gctggtctca gctgtcagtg cctgccgagt gttcaagctc    840

tggcccctgt ccttcctcgg gagcaaactc tccacgtgcg aacagctccg gcaccggctg    900

gagcacctca cgctaatctt cagtacacgg aaggcggaga accctgccca gctgatgagg    960

aaggccaaca cggtggcctc tgtgctgctg gacgtggccc tgggcctcat gctgctgtcc   1020

tggctccacg ggagaagccg catcgggcat ctggccgacg ccctcgttcc tgtggctgac   1080

cacgtggccg aggagctcca gcatctgctg cagtggctga tgggtgctcc cgccgggctc   1140

aagatgaacc gtgcactgga ccaggtgctg ggccgcttct tcctctacca catccacctg   1200

tggatcagct acatccacct catgtccccc ttcgtggagc acatcctttg gcacgtgggc   1260

ctctcggcct gcctgggcct gacggtggcc ctgtccctcc tctcggacat tatcgccctc   1320

ctcaccttcc acatctactg cttttacgtc tatggagcca ggctgtactg cctgaagatc   1380

catggcctgt cctcactgtg gcgtctgttc cgggggaaga agtggaacgt tctgcgccag   1440

cgcgtggact cctgttccta tgacctggac cagctgttca tcgggactct gctcttcacc   1500

atcctgctct tcctcctgcc taccacagcc ctgtactacc tggtgttcac cctgctccgg   1560

ctcctggtgg tcgccgtgca gggcctgatc catctgctcg tggacctcat caactccctg   1620

ccgctgtact cactgggtct tcggctctgc cggccctaca ggctggcggc tggcgtgaag   1680

ttccgtgtcc tccggcacga ggccggcagg cccctccgcc tcctgatgca gataaaccca   1740

ctgccctaca gccgcgtggt gcacacctac cgcctcccca gctgtggctg ccaccccaag   1800

cactcctggg gcgccctgtg ccgcaagctg ttccttgggg agctcatcta cccctggagg   1860

cagagagggg acaagcagga ctgagggaac tgctggctcg cctggcacca ccacacggcc   1920

acagccagcc atctgctctg ccagggtggc accagctcag ctggcgcatg tcctgtgctt   1980

tgtggacgct gctgtgtgct cctgaacacg gcaggccctg ctatcacacc ttgggcttgg   2040

aggtcattgg gagtgagcag atgtgggggt ggccagccag gctggccgca ctccatcact   2100

ggcactgcct gccttgggac ccgcttccca cctgctgcgg tcaccatggt ggcgagcaca   2160

gcaaccccag gtgtccagag cactgcccca tgcccaccct gtgtacccag gtccagaggg   2220

tccgtccacc acagcagccc caggtggagg gctggtctcc ctgggggctc cccagtggct   2280

ctgccctggc tgtgggggtg gagggacctt gccaggatga accccccagt cccaggcacc   2340

ctctagctcc ctcagccgaa cagcaccctg catctggggg attgaagcag tcgctgaccc   2400

ccgtccccag cgggcccggg ccctcactcc ctgaaccaca cggggtttat ttgcggatgt   2460

tccctggaga ggtcgctttg tgaagaaacc atcagcaggc tgtgagcatc gccaggctgc   2520

tgtgggggcg ggagcagcct cagtgtcaag ggcccgccca ctgacccagc cgtacctatt   2580

cgtccacggt gccccgtagc agcaggtcct gcggccaaat ctgtctccct tcatgggcct   2640

cccagggaag gaggaagccc tgctgtgcag acacctctgt ggccccccag gagtgtgagt   2700

ggcctgggga gggggccgtg gcactgaggc cgaaagtgcc tgccagacgg cacggtctgg   2760

gtgcgggtgt tccctgtgag cccgagtccg cttcaggagg ggagcctgca ggtgccggct   2820

ggtgagggga tgacgcgctg tgggtgggag gaggcagcgc ccatctcagc agcaccagga   2880

ctgcctggga ctccctggca acccagcacc ggggaagccg tcagctgctg tgacaataaa   2940

acctgccccg tgtctggagc gcaggctcgg tcccgggtcc atgtgaaaaa aaa          2993


<210>  705
<211>  2752
<212>  DNA
<213>  Human

<400>  705
accaattggg acatcacatc cctggctctg ggttagaaag ctgacagtcc ttgatcctgt     60

ggccactgcc ccatcattcc tgctcctgag gactcagtct catggctgtg gcagaggtgt    120

ccaggacctg cctgctcacg gttcgtgtcc tgcaggccca tcgcctaccc tctaaggacc    180

tagtgacccc ctctgactgc tacgtgactc tctggctgcc cacggcctgc agccacaggc    240

tccagacacg cacggtcaag aacagcagta gccctgtctg gaaccagagc tttcacttca    300

ggatccacag gcagctcaag aatgtcatgg aactgaaagt ctttgaccag gacctggtga    360

ccggagatga ccctgtgttg tcagtactgt ttgatgcggg gactctgcgg gctggggagt    420

tccggcgcga gagcttctca ctgagccctc agggtgaggg gcgcctggaa gttgaatttc    480

gcctgcagag tctggctgac cgtggcgagt ggctcgtcag caatggcgtt ctggtggccc    540

gggagctctc ctgcttgcac gttcaactgg aggagacagg agaccagaag tcctcagagc    600

acagagttca gcttgtggtt cctgggtcct gtgagggtcc gcaggaggcc tctgtgggca    660

ctggcacctt ccgcttccac tgcccagcct gctgggagca ggagctgagt attcgcctgc    720

aggatgcccc cgaggagcaa ctaaaggcgc cactgagtgc cctgccctct ggtcaagtgg    780

tgaggcttgt cttccccacg tcccaggagc ccctgatgag agtggagctg aaaaaagaag    840

caggactgag ggagctggcc gtgcgactgg gcttcgggcc ctgtgcagag gagcaggcct    900

tcctgagcag gaggaagcag gtggtggccg cggccttgag gcaggccctg cagctggacg    960

gagacctgca ggaggatgag atcccagtgg tagctattat ggccactggt ggtgggatcc   1020

gggcaatgac ttccctgtat gggcagctgg ctggcctgaa ggagctgggc ctcttggatt   1080

gcgtctccta catcaccggg gcctcgggct ccacctgggc cttggccaac ctttatgagg   1140

acccagagtg gtctcagaag gacctggcag ggcccactga gttgctgaag acccaggtga   1200

ccaagaacaa gctgggtgtg ctggccccca gccagctgca gcggtaccgg caggagctgg   1260

ccgagcgtgc ccgcttgggc tacccaagct gcttcaccaa cctgtgggcc ctcatcaacg   1320

aggcgctgct gcatgatgag ccccatgatc acaagctctc agatcaacgg gaggccctga   1380

gtcatggcca gaaccctctg cccatctact gtgccctcaa caccaaaggg cagagcctga   1440

ccacttttga atttggggag tggtgcgagt tctctcccta cgaggtcggc ttccccaagt   1500

acggggcctt catcccctct gagctctttg gctccgagtt ctttatgggg cagctgatga   1560

agaggcttcc tgagtcccgc atctgcttct tagaaggtat ctggagcaac ctgtatgcag   1620

ccaacctcca ggacagctta tactgggcct cagagcccag ccagttctgg gaccgctggg   1680

tcaggaacca ggccaacctg gacaaggagc aggtccccct tctgaagata gaagaaccac   1740

cctcaacagc cggcaggata gctgagtttt tcaccgatct tctgacgtgg cgtccactgg   1800

cccaggccac acataatttc ctgcgtggcc tccatttcca caaagactac tttcagcatc   1860

ctcacttctc cacatggaaa gctaccactc tggatgggct ccccaaccag ctgacaccct   1920

cggagcccca cctgtgcctg ctggatgttg gctacctcat caataccagc tgcctgcccc   1980

tcctgcagcc cactcgggac gtggacctca tcctgtcatt ggactacaac ctccacggag   2040

ccttccagca gttgcagctc ctgggccggt tctgccagga gcaggggatc ccgttcccac   2100

ccatctcgcc cagccccgaa gagcagctcc agcctcggga gtgccacacc ttctccgacc   2160

ccacctgccc cggagcccct gcggtgctgc actttcctct ggtcagcgac tccttccggg   2220

agtactcggc ccctggggtc cggcggacac ccgaggaggc ggcagctggg gaggtgaacc   2280

tgtcttcatc ggactctccc taccactaca cgaaggtgac ctacagccag gaggacgtgg   2340

acaagctgct gcacctgaca cattacaatg tctgcaacaa ccaggagcag ctgctggagg   2400

ctctgcgcca ggcagtgcag cggaggcggc agcgcaggcc ccactgatgg ccggggcccc   2460

tgccacccct aactctcatt cattccctgg ctgctgagtt gcaggtggga actgtcatca   2520

cgcagtgctt cagagcctcg ggctcaggtg gcacggtccc agggtccagg ctgagggctg   2580

ggagctccct tgcgcctcag cagtttgcag tggggtaagg aggccaagcc catttgtgta   2640

atcacccaaa accccccggc ctgtgcctgt tttcccttct gcgctacctt gagtagttgg   2700

agcacttgat acatcacaga ctcatacaaa tgtgaaaaaa aaaaaaaaaa aa           2752


<210>  706
<211>  1411
<212>  DNA
<213>  Human

<400>  706
attggacgcc gccggtcacg ggctcccgct tgggccagat ggtgctgagt ggggtcgaca     60

cggtgctggg gaagtcggag gagtgggcgg acaaccacct gccccttacg gatgccgaac    120

tggcccgcat cgccacatcc ctggatggct tcgacgtcgc gtccgtgcag cagcagcggc    180

aggaacagag ctacttcgta cgtctgggct ccctgtcgga gaggctgcgg cagcacgcct    240

atgagcactc gctgggcaag cttcgagcca ccaagcagag ggcacaggag gctctgctgc    300

agctgtcgca ggccctaagc ctgatggaaa ctgtcaagca aggcgttgat cagaagctgg    360

tggaaggcca ggagaagctg caccagatgt ggctcagctg gaaccagaag cagctccagg    420

gccccgagaa ggagccgccc aagccagagc aggtcgagtc ccgggcgctc accatgttcc    480

gggacattgc ccagcaactg caggccacct gtacctccct ggggtccagc attcagggcc    540

tccccaccaa tgtgaaggac caggtgcagc aggcccgccg ccaggtggag gacctccagg    600

ccacgttttc cagcatccac tccttccagg acctgtccag cagcattctg gcccagagcc    660

gtgagcgtgt cgccagcgcc cgcgaggccc tggaccacat ggtggaatat gtggcccaga    720

acacacctgt cacgtggctc gtgggaccct ttgcccctgg aatcactgag aaagccccgg    780

aggagaagaa gtagggggag aggagaggac tcagcgggcc ccgtctctat aatgcagctg    840

tgctctggag tcctcaaccc ggggctcatt tcaaacttat tttctagcca ctcctcccag    900

ctcttctgtg ctgtccactt gggaagctaa ggctctcaaa acgggcatca cccagttgac    960

ccatctctca gcctctctga gcttggaaga agcctgttct gagcctcacc cgtatcagtc   1020

agtagagaga gatgtccaga aaaaatatct ttcaggaaag ttctcccctg cagaattttt   1080

tttccttgtt aaatatcagg aatataggcc gggtgcggtg gctcacacct gtaatcccag   1140

cactttggga ggctgaggcg ggcggaacac ctgaggtcag gtgttcgaga ccagccaggc   1200

caacatggtg aaaccccgtc tctactaaaa atacaaaaaa aaatgagccg ggcatggtag   1260

caggtgtctg ttatcccagt taggaggctg aggcaagaga atctcttgaa cctgagaggc   1320

ggaggttgca gtgagccaag atcgcgccat tgcactccag cctgggggac aagagtgaga   1380

cttagtctca aaaaaaaaaa aaaaaaaaaa a                                  1411


<210>  707
<211>  2340
<212>  DNA
<213>  Human

<400>  707
gaacccggaa gttccgggcc gagttcctcg tgccaacgtg tcttgtaagg tgcggctaga     60

aactggggac atggcagcgc ctggcccagc gctctgcctc ttcgacgtgg atgggaccct    120

caccgccccg cggcagaaaa ttaccaaaga aatggatgac ttcctacaaa aattgaggca    180

gaagatcaaa atcggagtgg taggcggatc ggactttgag aaagtgcagg agcaactggg    240

aaatgatgtg gttgaaaaat acgattatgt gtttccagaa aatggcttgg tagcatacaa    300

agatgggaaa ctcttgtgta gacagaatat tcaaagtcat ctgggtgagg ccctaatcca    360

agatttaatc aactactgtc tgagctacat tgcgaaaatt aaactcccga agaagagggg    420

tactttcatt gaattccgaa atgggatgtt aaacgtgtcc cctattggaa gaagctgcag    480

ccaagaagaa cgcattgagt tctacgaact cgataaaaaa gaaaatataa gacaaaagtt    540

tgtagcagat ctacggaaag agtttgctgg aaaaggcctc acgttttcca taggaggcca    600

gatcagcttt gatgtctttc ctgatggatg ggacaagaga tactgtctgc gacatgtgga    660

aaatgacggt tataagacca tttatttctt tggagacaaa actatgccag gtggcaatga    720

ccatgagatc ttcacagacc ccagaaccat gggctactcc gtgacagcgc ctgaggacac    780

gcgcaggatc tgtgaactgc tgttctccta acgtgggagc gggaggggcg gggtcccggc    840

tgacaagcca gcatagggca ttcggtggcc agagccgagg gtcctcccac acgtgctcac    900

ccacccgcag cctaggcagg ctctgcatgc tatgccaggc atgtgcagtc tggacttcca    960

cctccagtgc cagaaacttc cagaaggaag gagaaaactc ttgtcaagaa tggcccagag   1020

gaatgcctcg cacaaaaggt cttccccacc cacccccagc cccctagtct aatacccacc   1080

ctgatacgtg caatcatgta gttttggcgg aaatttcccc atcattctag gatgatacag   1140

aaagaaaaac tgtgcctgga ccctccctct tggtgggtct gtggaaacat aagcggtttt   1200

tttaatgggc ccctgcatca ataccaaaca tgggggtttg gtaatgagaa accaggacag   1260

gccatctgca gtgacccagc ccaggacgaa gtttacaaac acctcctgga acgaagctcc   1320

cgcctgcatg tcaccttgat gggggctgtg agtggggcag tgtgataccc agtgactaga   1380

cgcactctgc gttttcccgt gtttggggct gaggcctgct ggacagatgg ctggccaagt   1440

gggagcagac cctagggagt ttgcacctcg gctgggccgg attcggaccg gctctgtgtt   1500

cactacactc agaatagcct ggctgcttct ctgtctccga gaccggaggt agtgggaacc   1560

aacagctggg ctggagagtt ggtgctggca aaacagtcct tgccctgggg ccggttctta   1620

cccaggtcca gagaaaccaa cgcgggatgt cagacttcac caaaaggact ttctggttgc   1680

ccctggctgg cttcctggag gcgttcgcct ctagtttctc agggatggag cgagagccca   1740

gccagagaac agtaagagga gctgctctcc tatctgcact cacccaggcc ttcacccaga   1800

ctttaccacg gaggcggctg agtgcagcta cagctaggtc cgcgtccctc actcttttca   1860

tcttctgcac gttcttcgtg aaactggaag gatcccgggt ctcagctaga acacggtgga   1920

agagaacttt cctaggaaac ggttcatgtg tcacttttca ggatgtggaa acactgagcc   1980

atacaccctc cattgcttgg tgctggggtt gtgtggcctc cactgggcac ttgccgacct   2040

gagtctgggg ccaggggagc ccaggctgcc ctgcactcct gcctcccagc ccacagccag   2100

gtgctttcat cacagctaaa cctggttccc tccaaacctc ccagccactc gggcttgtaa   2160

ctgtctgagc cccggatccg gtggggtgaa agcagccagc tcatcccagt gactcacagg   2220

acacagccat ccagcggcat ctttccttgt cgaatgatac tgtaatgacc ttccaaagtg   2280

aagagtagca cattaaagtg attttattgt ttcctgtttc tcaaaaaaaa aaaaaaaaaa   2340


<210>  708
<211>  4392
<212>  DNA
<213>  Human

<400>  708
agtggggaag aggacgggtc gagtgctggc ttccggcgga aaagcgcgcg agcaagatgg     60

ccaccaccaa gcgcgtcttg tacgtgggtg gactggcaga ggaagtggac gacaaagttc    120

ttcatgctgc gttcattcct tttggagaca tcacagatat tcagattcct ctggattatg    180

aaacagaaaa gcaccgagga tttgcttttg ttgaatttga gttggcagag gatgctgcag    240

cagctatcga caacatgaat gaatctgagc tttttggacg tacaattcgt gtcaatttgg    300

ccaaaccaat gagaattaag gaaggctctt ccaggccagt ttggtcagat gatgactggt    360

tgaagaagtt ttctgggaag acgcttgaag agaataaaga ggaagaaggg tcagagcctc    420

ccaaagcaga gacccaggag ggagagccca ttgctaaaaa ggcccgctca aatcctcagg    480

tgtacatgga catcaagatt gggaacaagc cggctggccg catccagatg ctcctgcgtt    540

ctgatgtcgt gcccatgaca gcagagaatt tccgctgcct gtgcactcat gaaaagggct    600

ttggctttaa gggaagcagc ttccaccgca tcatccccca gttcatgtgc cagggcggtg    660

atttcacaaa ccacaatggc actgggggca agtccatcta tgggaagaag ttcgatgatg    720

aaaactttat cctcaagcat acgggaccag gtctactatc catggccaac tctggcccaa    780

acaccaatgg ctctcagttc ttcctgacat gtgacaagac agactggctg gatggcaagc    840

atgtggtgtt tggagaggtc accgaaggcc tagatgtctt gcggcaaatt gaggcccagg    900

gcagcaagga cgggaagcca aagcagaagg tgatcatcgc cgactgtggg gagtacgtgt    960

gaggcggcac tctctctgct tccccctccg ctcttgaccc tgcatatcca ggaaggaact   1020

gccagcctca gaggaggcag caccgagggt gcctgtttga agcaagcagc atttgggata   1080

tgtgcccttc ctcagggtct gcttggagca gctcctctgc aggcacagcc tggactattc   1140

ccaggcacag ctgtgggccc aggagccagc tcaggtgctc ccctccacca tgggcaggct   1200

gtgcaaaaag ccactggctt ttctcagcat ttgctgctgg gcctctcctg ggactaccag   1260

tgtggctctt acgtgttttc tttgctaaaa taaaccctag ttcttatatt gctcttcctg   1320

ctagttcttg ggagttgtca gagattgtgt ctgtggctaa gctggacctc tgaggcaggc   1380

tggtgagtgg ggagagcaga gcatcttttt cacagctttc atttcctccc ttgggccgat   1440

ccccttagat gtcaggtgat gtatcttcac accaggcatc gatgtcaggg caacggaaat   1500

taaagactgg aaagctccgg tcttctgctg cctctgctcc taaacccagc tgccggcctt   1560

acagccagca agtgtactct cagtggttca tttgtttatt tgttcacttt caccctacag   1620

attttaaaaa atgaaatttt tataactcaa agtgccttct ctgtgccaag tactatgcct   1680

atttgtcagg agacaggaag ccaacaaact acatgtgcct aatccagccc actgcctgtt   1740

tttatgaatc aggttttatt ggaacacagc cacgtccatt tatttacata ttgtccatgg   1800

tggtttctta ctgcagtggc agaggtgcgt aaggggctat agacacaata caggctatgg   1860

tccctgtatt agggttttct agagaagcag aaccaatagg gtgtgtatat atgtagaaag   1920

agatttattt taaggaactg gctcaagcag tggtaggagc tggcaagtct gcaatctgca   1980

caacagacca gcaggctgga gactcaggaa aaaaactgat gttgcagttc agctctgagg   2040

cagtttggaa gcagaattct tcctccagtg atctcagtct tttttctctt aagaatttca   2100

actgattgga tgaggcctac ccacattatg gagggtaatc tgctttactc tctactgact   2160

taaatattaa tccatctaaa aaataggcca ggcatggtgg ctcatgccta taattccacc   2220

actattggga ggctgaggca ggaggatcac ttgagcccag gagttcaaga ccagcctggg   2280

caatgtagag acccccatct ctagggggag aaaaaaaagc caggtatggt agtgcacacc   2340

tatagtccca gctactcaga aggctgaggt gggaggatcg cttgaacctg ggaggttgag   2400

gctgcagtca gccatggtca tgccactgta ctccagcctg ggtgacaaga gggagaccct   2460

gtcttgaaaa aaagaaacca tcatcacagc aacatctaga ctagtgtttg actaaaaact   2520

ggataccatg gcctagccaa attgacacac aaaatagacc atcacagtcc caaggcctaa   2580

aatacttact atctgagcct ttacaaaaca ggattgccag ccactgaaga gaacaaatgg   2640

tcccaccccc tgctgagctc acagtctggc tctcctgtgt gcagccactt cttggagctg   2700

gcttctctcc actccccctc cagatgctgg tcagccaggc ggttataaag aatctcatct   2760

gctgaaggct tttagcaggg actgagtcct gtagctgttg gacacctcct gtgggttggg   2820

tcactcagac cattcagaat ccactgagct gagcttttgc atcttggatt gagatctgga   2880

tgagccagga ggcaggagag gctaggtggt cctcatgacc ctaggatagc tcttgctgag   2940

ggatggtggc attctgccct acctctggct cccatgtgcc gactggactt tgtgagctcc   3000

agctgctaca gttgactgag ttcaggctcc atgtagctgg gatatactac atggttaccc   3060

ctcaccccta tggagcttcc aaaagagacc ctccctcaaa gcacagcccc ttctctgagt   3120

gcaaataatg gccatcagag gtcagtcaca ggtgttaggc aggcatctat gaagctgggg   3180

atgatagcac tgacttcagt gcttggacga gaaccaggag agagtgtgta gaaaaagcac   3240

agccagcctc ccataaaagg acagactcct gtgacaacct tgtcactctg ttcctccctg   3300

atactctggg gaggtggagg ccagtgggca gttctgaaag ctcagcaggt ttggagccat   3360

tgggtgtgga ctcctctccc agtgttcctc ctgggtgttc acagatgtta ttgaatgcac   3420

actggaaccc tgcacaggta aactgaggct ttattggcgt gactgccaaa ggtcacacag   3480

ggtggtttgg cagagctggg attagaagcc cagcctgtct ctcttcagta gtaatggagt   3540

cctgggaggt ttactaggct ttagcctcaa tctgtggcgg cagggtccac agccctgggg   3600

agtgacacag tcatggtccc catgattggc caggacctgt gtggagagac acaggagaca   3660

agaccctgct cttccaggcc agaagggagg ggagccccag agctgggcag tggcatgccc   3720

cacagcctgg ccacctgctt cggctacgca ccatgcagca gctgcacctg gctgcctcgg   3780

gaaaactctg acctctctgg gaagtggagc cagtggctct gtgggcgtcc tttcctgcag   3840

cctggagagc aaagcggctt tccctgggac tgtgtggctc ctgtcccaac tggcctcccc   3900

attccacatt cccattgctg gaccagcacc aggactgggc acagggcttc cttttgctga   3960

ttcatttccc ccctaactca ttcagagttg agccccatct gagtccccac atgctggccc   4020

tgaaacggtt acaaaggctg aaaccaggga tggcaggccc aggatcagtg ctgtggctgt   4080

tggagtgtcc tctccaacag catgacagcc gcctccaggt gctcccagca tctgttgcag   4140

tcatggcagc ctcacggcaa cctctgaaga aggaattata gaaccaactt tttattgttg   4200

aaaatggagt cttgtagagt tcagtgatgg gaaactaaag tagaaaaagc acatcacaaa   4260

gaaacatata tagtacagtg tgatcccaat tttgtaaaaa tatctgtaat atgtaagcat   4320

aggtatttgt atatcttaag aaaaaaagcc tagaaataaa gccacaaaaa tattaaaaaa   4380

aaaaaaaaaa aa                                                       4392


<210>  709
<211>  869
<212>  DNA
<213>  Human

<400>  709
gtgacagagc gctttacgac agttgctttg aggcagtacc ggaggagaaa gatggcggct     60

accttactag ctgctcgggg agccgggcca gcaccggctt gggggccgga ggcgttcact    120

ccagactggg aaagccgaga agtttccact gggaccacta tcatggccgt gcagtttgac    180

gggggcgtgg ttctgggggc ggactccaga acaaccactg ggtcctacat cgccaatcga    240

gtgactgaca agctgacacc tattcacgac cgcattttct gctgtcgctc aggctcagct    300

gctgataccc aggcagtagc tgatgctgtc acctaccagc tcggtttcca cagcattgaa    360

ctgaatgagc ctccactggt ccacacagca gccagcctct ttaaggagat gtgttaccga    420

taccgggaag acctgatggc gggaatcatc atcgcaggct gggaccctca agaaggaggg    480

caggtgtact cagtgcctat ggggggtatg atggtaaggc agtcctttgc cattggaggc    540

tccgggagct cctacatcta tggctatgtt gatgctacct accgggaagg catgaccaag    600

gaagagtgtc tgcaattcac tgccaatgct ctcgctttgg ccatggagcg ggatggctcc    660

agtggaggag tgatccgcct ggcagccatt gcagagtcag gggtagagcg gcaagtactt    720

ttgggagacc agatacccaa attcgccgtt gccactttac cacccgcctg aatcctggga    780

ttctagtatg caataagaga tgccctgtac tgatgcaaaa tttaataaag tttgtcacag    840

agaatctttg taaaaaaaaa aaaaaaaaa                                      869


<210>  710
<211>  4790
<212>  DNA
<213>  Human

<400>  710
cctttccaaa gccaggctga gagggtgggg agagcccatg cgcctgggaa gccgggctgt     60

ttctgggcgg ggctgcagac tcctcgtgct cgtgtcaccg tgtccttccc aggagacaga    120

gaaggaggag agcccggaac cagggccgga gcggcgggcg gagccgagct gcggggagcc    180

gctccgggtg cccccacccc cgcgcgcctc agtggtgccg gccgagggca gggctcgcgg    240

ttgcggggct cgcgccgctg tcagtgcggc ggggcgcgcg agcggcgcca gctcggggca    300

gcggaaccca gagaagctga gggggcggta gcggcggcga cggcgacgac gacgactccc    360

gcgcgtgtgc ccagcctctt cccgccgcag ccgccctttt cctccctccc ttacgtcccc    420

gagtgcggca gtaccgcctc cttcccagcc gcgcggcttc ctccagacct ctcggcgcgg    480

gtgagcccta ttcccagagg caggtggtgc tgaccctgta acccaaagga ggaaacagct    540

ggctaagctc atcattgtta ctggtgggca ccatgtcctt gaagcttcag gcaagcaatg    600

taaccaacaa gaatgacccc aagtccatca actctcgagt cttcattgga aacctcaaca    660

cagctctggt gaagaaatca gatgtggaga ccatcttctc taagtatggc cgtgtggccg    720

gctgttctgt gcacaagggc tatgcctttg ttcagtactc caatgagcgc catgcccggg    780

cagctgtgct gggagagaat gggcgggtgc tggccgggca gaccctggac atcaacatgg    840

ctggagagcc taagcctgac agacccaagg ggctaaagag agcagcatct gccatataca    900

gtggctacat ctttgactat gattactacc gggacgactt ctacgacagg ctcttcgact    960

accggggccg tctgtcgccc gtgccagtgc ccagggcggt ccctgtgaag cgaccccggg   1020

tcacagtccc tttggtccgg cgtgtcaaaa ctaacgtacc tgtcaagctc tttgcccgct   1080

ccacagctgt caccaccagc tcagccaaga tcaagttaaa gagcagtgag ctgcaggcca   1140

tcaagacgga gctgacacag atcaagtcca atatcgatgc cctgctgagc cgcttggagc   1200

agatcgctgc ggagcaaaag gccaatccag atggcaagaa gaagggtgat ggaggtggcg   1260

ccggcggcgg cggcggtggt ggtggcagcg gtggcggtgg cagtggtggt ggcggtggcg   1320

gtggcagcag ccggccacca gccccccaag agaacacaac ttctgaggca ggcctgcccc   1380

agggggaagc acggacccga gacgacggcg atgaggaagg gctcctgaca cacagcgagg   1440

aagagctgga acacagccag gacacagacg cggatgatgg ggccttgcag taagcagcct   1500

gacaggagca atggccacca gcaggtgaag ggcatcgctg ccccaggcct caagccgggc   1560

acccaaccct ggatgccacc ccccagcggg taccagagga aagctggcag caggcgcctc   1620

ctcccccaac gcatcccagc cagtgccatg tcctctgcag gtggagttac tggcctactc   1680

cttccccatg agccctccct gtctgcactg cccaggccag agggtagagc acaggggttt   1740

ccccatacta cctcccctcc ccaggacact cccaggcttg ggttttttct ataggtttgg   1800

cggggggcca cagggagggg accctgacaa taaagagatt ggatcccaac ctgttctgag   1860

atgggatggt ttgtgttttc tcatgaagat atcccggccc ctctgccaac caaaaagctg   1920

gtctagggtg cctaatactg atccatctgg accttagtgt cctcagtggt gattaaaatg   1980

gccagtgggg ccactgggga gggttggata tgctggccca tgagcatctt gctggctgaa   2040

gtgtcaagca gttgtgaccc acttggttta ccccatagta ggtcaagacc ttatctcttt   2100

ccccagcttc taagtctggt ctttcccagc tcttaaaagg attctagagt ctgccagtct   2160

ctaccttctc tcttctggct taggacacta taattttttc atttggacgt tgtcctccca   2220

ccagcctccc agtcttctgc ctctgccctg taccatctcc cagcagccac gcagtctttc   2280

tgaaacgtat cccttccctg cctaaaatcc ctttactgac tcttcatcat caggacaaaa   2340

ccctacctcc tgaatgtagg gtgtaagatc ctgcttactc cagcctctcc tgtttcttgt   2400

caccacccct ttcctgcccc tgacacaaac cctacatctc agtctcacaa aacacacaag   2460

ttcttcacac tccgggcagg tttggtagca aggaatagag cgtactccag tgacagcaat   2520

cagtaggaag tttgcatccg gagacacgca gcctgtctgc ccctgtcttg ggccacccgt   2580

ctagacattt gttctctaac aatcagccgg gttccttcaa acgtgtgctg cttatacatg   2640

ctcattgtgt actgctaatg tcacctactt cccccttcat tccccacaat gaatggatcc   2700

attttcccca tgttcaagtt cccaagagag aatcgactgc cactgtaatt ttttttccta   2760

atcactcata ggttacaagt acctaccctg gtccagtgaa ctgcgggatt catatgtggc   2820

cacttaggct ggtctcgttg gtatggagct gtgggagggc agcacccaga aataggcttt   2880

gttccaggcc tggcacgtac tcctcctgct cctactttct ctacctggga aatagccgct   2940

caggacgaag ctgctgctgt ggtgtcgcca cctctgagaa gtctcccaga ccctccgact   3000

gctctttaat tgcctgttct ctcctctgga agccttcccc caacacagaa aaattcaatc   3060

ccatcatcaa aaagggcttt aggttttccc tccatcttta cgtgttgatc aaagtttgca   3120

gatctgctgg aatccttatt gaaaactccc catttcaaac caacccggtc tacagcctcc   3180

agggaagctt cctcctgggc tttggctcca tgttttggta gagggtggag gctttgggca   3240

gtgctcaaac tccaccggga agtctctctc actgagcagc cctcctgcct gtcatcctgg   3300

gcaggcgagc actctgaggc cccagtgtag ctctgtgctt tgatattccc aagctctgct   3360

ggggcctgac taggccagcc ccaaggtggc cagagttctg gcttcatacc tgagccaaaa   3420

gccccaatcc atgcttggcc attgcctgag tattagctgc cccaggggga tcacggtccc   3480

catatatttg cttgccatgg accctgggca gcagggagag agtagagatt tgtcaagagc   3540

ccatggtgga ggctgaggcc ctgaggccat gagatgcagg catggggtga gaaacaggcc   3600

ccttggaatt gggctgggcc ttggcccagc ttagtcaaat caaaaggctt ctatttggag   3660

agctgaagag ggtgtacaga ggaaggggct aggtctgcaa ggagtgcctc atctccctga   3720

agagctctca gtggaacata cttcacccat ccatgtaccc acatctttcc ttgcccagaa   3780

ggcgagagcc agctataaca gacccatttc aataccctgg caagtcatta ctgcccttag   3840

ctcttggtgt ccccatctgt gaaacatggg ggacagctgc tagcctggat tggaacttgg   3900

gcaaagtcca aagaatggga tttagagctg aatgaacctc acactgaggg cacaatagca   3960

ctaggcactg cccccagagc ctagtgctat atgcctgctg caggtcctac ccaagcatgc   4020

tttactgagg aactcaacgt ttcagagctt gagggtcagg ttgatcatgg gcttgtgacc   4080

ataggcttcc ttagtatgcc aggcttggag aaccgtgaga aaagcaggga agataccttc   4140

aagggtagca ggcatcagct ctactcacct tggcccataa ggctttgcct ggtcatgctg   4200

gcaccgggtc atatgctgga cagggagaac gagagtccca tcctggaact ccagaaaagc   4260

ccctggatgc tccagcccct gggaaagcac acagccaggc ccttgggtgg gaggttggct   4320

tctaacagtg catacacatg cccttcctct gagtcggggc agcaaaaaca tccattccgc   4380

tgcgcaacag ttgtcatttt tctaacatct gaaaactcca gaaggagatg gtgataaatg   4440

tggtaccgga ttctgcctaa aggatcagtc tttagatgtt ttcagattga aagcctcatt   4500

tgtgatcctc acagccatct tgaaagaata gagcagccag tgggtatact ggattgtgag   4560

ctaagaggcc tgggactttc cccctgttgc tgccagccag gttgatgacc ctgggcaagt   4620

ctttttcctt accaggtctc agtttcctca gctgtaaaat gagaggttga tctggatcag   4680

ggatagtaaa tgggcctttg ttcagttact gactgttgta taacaaacca cccccaaatt   4740

tagtagcctt aataaacatt tattagctcc tgaaaaaaaa aaaaaaaaaa              4790


<210>  711
<211>  3178
<212>  DNA
<213>  Human

<400>  711
cttagtaggt ggatggtggt cggagcgccg actcccttct cgtcgtcgcc attttgagct     60

ggtgactgtg gccggctggg agtaggcggc agtgagtttc cctgggaggg cagcgcgctt    120

ggcgcttctc ccctcccccc gatctgcctc cagtctcgga cttggttgtt gcgcgctccg    180

gctccggctg agctgggaga gttggaggag gtggcggcgg gcagaggtga tgtctgggag    240

cccttccttg acagcccggg ccgagaagag tccctgcagg aagcatcacc caggctggca    300

gatcatggta gcagcagcgg gggtggctgg gaagtgaaac ggagccagcg gctgaggagg    360

ggccccagca gcccccgaag gccctatcag gacatggagt atgaaagacg tggtggtcgt    420

ggtgacagga ctggccgcta tggagccact gaccgctcgc aggatgatgg tggggagaac    480

cgcagccgag accacgacta ccgggacatg gactaccgtt catatcctcg cgagtatggc    540

agccaggagg gcaagcatga ctatgacgac tcatctgagg agcagagtgc ggagatccgt    600

ggccagctgc agtcgcacgg cgtgcaagca cgggaggttc ggctgatgcg gaacaaatct    660

tcaggtcaga gccggggctt cgccttcgtc gagtttagtc acttgcagga cgctacacga    720

tggatggaag ccaatcagca ctccctcaac atcctgggcc agaaggtgtc gatgcactac    780

agtgacccca agcccaagat caatgaggac tggctgtgca ataagtgtgg cgtccagaac    840

ttcaaacgcc gagagaagtg cttcaaatgt ggcgtgccca agtcagaggc agagcagaag    900

ctgcccctcg gcacgaggct ggatcagcag acactgccac tgggtggccg ggagctgagc    960

cagggcctgc ttcccctgcc gcagccctac caggcccagg gagtcctggc ctcccaagcc   1020

ctgtcacagg gctcggagcc aagctcagag aacgccaatg acaccatcat tttgcgcaac   1080

ctgaacccac acagcaccat ggattccatc ctgggggccc tggcacccta cgcggtgctg   1140

tcctcctcca acgtgcgcgt cataaaggac aagcagaccc aactgaaccg cggctttgcc   1200

ttcatccagc tctccaccat cgaggcagcc cagctgctgc agatcctgca ggccctgcac   1260

ccaccactca ctatcgacgg caagaccatc aatgttgagt ttgccaaggg ttctaagagg   1320

gacatggcct ccaatgaagg cagtcgcatc agtgctgcct ctgtggccag cactgccatt   1380

gctgcggccc agtgggccat ctcacaggcc tcccaaggtg gggagggtac ctgggccacc   1440

tccgaggagc cgccggtcga ctacagctac taccaacagg atgagggcta tggcaacagc   1500

cagggcacag agtcttccct ctatgcccat ggctacctca agggcaccaa gggccctggc   1560

atcactggaa ccaaagggga tcccactgga gcaggtcccg aggcctccct agagcctggg   1620

gccgactctg tgtcgatgca ggctttctct cgcgcccagc ctggtgctgc tcctggcatc   1680

taccaacaat cagccgaggc gagcagtagc cagggcactg ctgccaacag ccagtcgtat   1740

accatcatgt cacccgctgt gctcaaatct gagctccaga gccctaccca tcctagttct   1800

gctctcccac cggctaccag ccccactgcc caggaatcct acagccagta ccctgttccc   1860

gacgtctcta cctaccagta cgatgagacc tccggctact actatgaccc ccagaccggc   1920

ctctactatg accccaactc ccagtattac tacaatgctc agagccagca gtacctgtac   1980

tgggatgggg agaggcggac ctatgttccc gccctggagc agtcggccga cggacataag   2040

gagacagggg caccctcgaa ggagggcaaa gagaagaagg agaagcacaa gaccaagaca   2100

gctcaacaga ttgccaagga catggaacgc tgggcccgca gtctcaacaa acaaaaagaa   2160

aacttcaaaa atagcttcca gcctatcagc tccctgcgag atgacgagag gcgggagtca   2220

gccactgcag atgctggcta tgccatcctc gagaagaagg gagcactagc cgagagacag   2280

cacaccagca tggatctccc gaaattggcc agtgacgacc gcccaagccc tccgcgagga   2340

ctggtggcag cctacagcgg ggagagtgac agtgaggagg agcaggagcg tgggggccct   2400

gagcgggagg agaagctcac cgactggcag aagctggcct gtctgctctg ccgacgccag   2460

ttccccagca aagaggcgct catccggcac cagcagctct cagggctcca caagcaaaac   2520

cttgagattc accggcgagc ccacttgtca gaaaacgagc tagaagcact agagaagaat   2580

gacatggagc aaatgaagta ccgggaccgt gcagctgaac gcagagaaaa gtatggcatc   2640

cccgagccgc cagagcccaa gaggaggaag tacggcggca tatccacagc ctctgtagac   2700

ttcgagcagc ctactcggga cgggctgggc agtgacaaca ttggcagtcg gatgctgcag   2760

gccatgggct ggaaagaggg cagcggcctg ggccgcaaga agcagggcat tgtaacgcct   2820

atcgaggccc aaacacgggt gcggggctcc ggcctgggtg cacggggcag ctcctacggg   2880

gtcacctcaa ccgagtccta caaggagaca ctgcacaaga caatggtgac ccgcttcaac   2940

gaggcccagt gagcagcttc aagagcaact tctccacatg ttgggtgtcc atcctggggc   3000

agggaaggac agagtgttgg atggctggga cggggccttg ctcttgtcgg ccagcccact   3060

ccccagccag agagggcttg accaaatcaa attgaggtgg tgacttttgt tggaaaattg   3120

ggctgggatc acgtcctgtt ttgtaataaa agctgaaaag tctgcatgaa aaaaaaaa     3178


<210>  712
<211>  4496
<212>  DNA
<213>  Human

<400>  712
cttccggaca ggtcaggcca aggtctcagc cacgtgactg tgttccggct cggtaaagat     60

ggcggcgccc agggcggtag cgtgaaactt ggtggaagac gctgaccagt cgtgttggaa    120

tcaaaacagc ggggaccctg cgccatgtcg cgactgatcg tgaagaatct cccgaatggg    180

atgaaggagg agcgtttcag gcagctgttt gccgccttcg gcacgctgac agactgcagc    240

ctgaagttca ccaaagatgg caagttccgc aagtttggtt ttattggctt caagtccgag    300

gaagaggccc agaaggcaca gaagcatttc aacaagagct tcatcgacac atcccggatc    360

acagtggagt tctgcaagtc attcggggac ccggccaaac ccagagcctg gagcaaacat    420

gcccagaaac caagccagcc caagcagcct ccaaaagact ctactactcc agaaattaag    480

aaagatgaga agaagaaaaa ggtggcaggt caactggaga agctgaagga ggatacagag    540

ttccaggagt ttctgtcagt tcatcagagg cgggcgcagg cagccacttg ggcgaatgat    600

ggcctggatg ctgagccctc gaaagggaag agcaagccgg ccagtgacta cctgaacttc    660

gactccgatt ctgggcagga gagtgaggag gagggagccg gggaggacct ggaagaagag    720

gcaagcctcg aaccaaaggc agctgtgcag aaggagctgt cggacatgga ttacctgaaa    780

tccaagatgg tgaaggctgg gtcgtcctct tcctcggagg aagaggaaag tgaagatgaa    840

gccgtgcact gtgatgaagg gagtgaggcc gaggaagagg attcctccgc caccccagtc    900

ctgcaggaaa gagacagcaa gggtgcaggc caagagcaag ggatgccagc tgggaaaaag    960

agaccaccgg aggccagagc cgagacagag aaaccagcaa accagaagga acccaccacc   1020

tgccacaccg tgaagctgcg gggagccccg ttcaatgtca cagagaaaaa tgttatggaa   1080

ttcctggcac ccctgaaacc agtggccatt cgaattgtga gaaacgctca tgggaataaa   1140

acaggataca tctttgtgga tttcagcaat gaagaggaag tgaagcaagc tctgaaatgc   1200

aaccgggagt acatgggtgg gcgctacatc gaggtgttca gggaaaagaa cgtccccacc   1260

accaagggtg caccaaagaa taccaccaaa tcctggcaag gccggatact cggggagaac   1320

gaagaggagg aggacctggc cgaatccgga aggctctttg tacggaacct gccctacacc   1380

agcaccgagg aggatctgga gaagctcttc tccaaatatg gtcccctgtc tgagctccac   1440

taccccatcg acagcctgac caagaaaccc aagggttttg cattcatcac cttcatgttc   1500

cctgagcacg ctgtgaaggc ctactcggag gtggacgggc aggtattcca gggcaggatg   1560

ctccacgtgt taccatctac catcaagaag gaagccagcg aggatgccag tgccctggga   1620

tcgtcgtcct acaagaagaa gaaggaggcc caggacaaag ccaacagtgc cagctctcac   1680

aactggaaca cactattcat ggggccgaat gccgtggccg atgccatcgc acagaagtac   1740

aacgccacca agagtcaagt gtttgaccac gagaccaagg gcagcgtggc cgtgcgcgtg   1800

gctctggggg aaacccagct cgtccaggaa gtgcggcgtt ttctcataga caacggggtc   1860

agcctggatt ccttcagcca ggctgcagca gagcgaagca agactgtgat tctggtcaag   1920

aacctcccgg caggcaccct ggcggcccag ctgcaggaga ccttcggcca ttttggcagc   1980

ctgggccgcg tgctgctgcc agagggcgga atcactgcca tcgtggagtt cctggagccc   2040

ctggaggccc gcaaggcctt caggcatctg gcctattcca agttccatca tgtccccctc   2100

tatctggagt gggctccagt tggcgtcttc tccagcacag ccccacagaa gaaaaagctc   2160

caagacacac cttcagaacc catggaaaag gacccagcag agccagaaac agtgcctgat   2220

ggcgaaaccc cagaagatga aaatccaaca gaggaaggag cagacaactc ttcagcaaag   2280

atggaagagg aggaggagga agaggaagaa gaagaagaga gcctcccagg atgtactctg   2340

tttattaaga atctcaattt tgacacaaca gaagagaagc tgaaggaagt gttttcaaaa   2400

gtggggacag tgaagagctg ctccatctcc aagaagaaga acaaagcagg agtgctcctt   2460

tccatggggt ttggatttgt ggaatacagg aagccggagc aagcccagaa agctctcaag   2520

cagctccagg gtcacgtcgt ggacggccac aagctggaag tgaggatctc ggaacgagcc   2580

actaagccag ccgtgacatt ggctcggaag aaacaagttc ccagaaagca gaccacctcc   2640

aagatcctgg tgcggaacat ccccttccag gcccacagcc gggagatccg agagctcttc   2700

agcacctttg gggagttgaa gacggtccgc ctgccaaaga agatgactgg gacaggcaca   2760

cacagaggct tcggctttgt ggacttcctc accaagcagg atgcgaagag agccttcaac   2820

gccctgtgtc acagcaccca cttgtacggg cggaggctgg tgctggagtg ggccgactcc   2880

gaggtgaccc tgcaggccct gcggcggaag acggccgctc actttcacga gcccccgaag   2940

aaaaagcggt ctgtggtgtt ggacgagatc ctggagcagc tggaaggcag tgacagcgac   3000

agcgaggagc agacccttca gctgtgagct ggcaccgaga gggctggagt gcagtggcgt   3060

gatctgggct cacctccctg gttcaagcga ttgtcccgcc tcagcctccc aaggctggga   3120

ttacaggtat gcaccaccac gcccggctaa ttttgtattt ttcatagaga ctgggtttca   3180

ccatgtagac caggctggtc tcgaattcct gacctcaagt gatccaccta cctcggcctc   3240

ccaaagtgtg gggattacgg gtgtgagcca ccacgcccgg ctaatttttt gtatttttag   3300

tagacagggt ttcaccatgt gggccaggct ggtcttgaac tcccaacctc aagtgatcca   3360

cccaccttgt tctcccaaag tgctgagatt acaggtgtga gccaccatgc ccagcctgtt   3420

cctaaccctt tcaactgggg ggtctcaagt gggtgaggac tccatggcca cggcagcaga   3480

actgtctctt ctgaaaacca gactccgggg cccctgggtc agcacctcta ggtcattcca   3540

cagacttaca cagtttaaag aaagagccag cgaacatggg gtgatcctgg ggtgccactg   3600

ggatcccaag ccaggcccgg aggtctgcct gtttcgtccc cagaaacttg agctggcatc   3660

ctccgctggt ttgcactggg cacggggact ggagagccac caggccactg agcgcagcat   3720

gctatcactt ctcaggaagt tgtgagggtg aggagaatag ccgggcccac tctgcagagg   3780

ggaggaacag gcacaggcta gaggcacggg ctgatagagt gagtcctctc cctcattcat   3840

tcattcattc attcattcat ccatcagaca cctgctgggc atctgctgtg tgcgagacac   3900

tgtgctgggt gccccagaca caagacagaa actcgggtcg ctctgtgtgc ctccacactg   3960

gccttccctg ctgcgtggac gcaggctctg tctcctaggc tttaagcccc atgcatcagg   4020

tggaagacaa tttccagcag cctctgcccg cttgtttttc ctcctctcct tttcctgccg   4080

ccttggtctt ttttgtcttt tgtgcagggc cgtctctcgc agcgcccgtc tgtgctccgc   4140

agcgtctagg aaaggattag tgtgagcaga gcacgcaggc tttggtgaac agagccgagc   4200

ttggtttcaa catctaattc aatttgttct gccgagattg aaatatgaaa tggttgccag   4260

tcaaacgttc aaaggacggg gaagggagag tgagcgcatg ctgaaattta aattttaatg   4320

aaaatgactt taaccctttg gtacaccttg caaaatgtaa cccatcctcc catcctgtga   4380

aagcggcctc tcgggttaga gcttttccac ccacttctct tccactgagc ttcactaata   4440

atatgtaatc atttttttca gccgtcttaa taataaaaga ttaatagaat gaaaaa       4496


<210>  713
<211>  9443
<212>  DNA
<213>  Human

<400>  713
aaagcagtat gtgctgagag aggaggatta agctcctgga ggcagagctc tcccacacac     60

ttgctggctt gctgggctcc actgactgga ctgaaaacag ggccaagaaa actgctgctg    120

cagggggtcc tgaaaacagc tggaacccgg cagtgatgtg ggacctaact tgaagttaac    180

ctgtggtggt gaggttggaa ccagttggat tatgatttat tttctacact cttgtacgga    240

atgcagagct gttgtatcct gatgaatcta ctgctaaata tagtcatttg gaataatttt    300

aagtattgat cttaaaactt gtaccacaac aagagtgtct aaaaagcacg gcaagctcat    360

tacgttctta cgaacattca tgaagtctcg tccaacaaaa cagaagctga agcagcgggg    420

aatcttgaaa gagagggtgt ttggttgtga cctgggggaa caccttctaa attctggttt    480

tgaagtgccg caggttcttc aaagctgcac agcattcatt gagagatatg gcatcgtgga    540

tggaatctat cgcctttctg gtgttgcctc caatatccag agactacgcc atgaatttga    600

ctctgagcac gtccccgacc tgacgaaaga accgtatgtt caggacatcc attctgtggg    660

ttccctatgt aagctgtact tccgggaact cccaaaccct ctgcttacct accagctgta    720

tgagaaattt tctgatgcag tttcagcagc aacagatgaa gaaaggctga taaaaatcca    780

cgatgtcatc cagcagctcc ccccaccaca ctacagaaca ctggagttcc tgatgagaca    840

cttgtctctt ctagctgact attgttccat cacaaatatg catgcaaaaa atctagcaat    900

tgtttgggct ccaaacctgt taagatcaaa acagatagaa tctgcctgct tcagtggaac    960

agcagctttc atggaagtga ggattcagtc tgtggttgtt gagttcatcc tgaatcacgt   1020

tgatgtgctg ttcagcggca gaatcagcat ggccatgcaa gagggggcag cttctctatc   1080

aaggcccaag tccctcctgg tatcctctcc atccaccaaa ctgctgacat tggaagaggc   1140

ccaggcacga acacaagctc aggtcaattc tccaattgtg acggaaaata aatatatcga   1200

agtaggagaa ggacctgctg cacttcaggg gaaatttcat accataattg agttcccact   1260

tgaaagaaag aggcctcaaa ataagatgaa aaagtctcct gtgggtagct ggcgttcctt   1320

tttcaacttg gggaaatcat catctgtttc taaacgaaag ctgcagcgga atgagagtga   1380

gccttcagag atgaaagcca tggctctgaa aggtggcagg gcagaaggaa ccctccgttc   1440

agctaaaagt gaggagtctc ttacatctct ccatgcagtt gatggtgatt ctaagctctt   1500

ccgacccaga agacccagat cttccagtga tgcactgtct gcctctttta atggagaaat   1560

gctggggaac cgctgtaact cctatgataa tctgcctcat gacaatgaga gtgaggagga   1620

aggagggctg cttcatatcc cagcccttat gtctcctcat tcagctgagg atgttgactt   1680

gagcccacca gacattggag tagccagcct ggattttgat ccaatgtcat ttcaatgtag   1740

tcctcctaag gccgaatcag aatgtctgga gagtggtgct tcctttttag attcaccagg   1800

atactccaag gataaaccaa gtgccaataa aaaggatgca gaaacaggta gtagccaatg   1860

tcagactcca ggaagcacag caagctctga acctgtctct cctcttcagg agaaactgag   1920

tccattcttt accctggact tgagcccaac tgaagataaa tcatctaagc catcctcctt   1980

tactgaaaag gtcgtctatg ctttctctcc gaagatagga cggaaattaa gcaaatcacc   2040

ttctatgagc atatctgagc caatttcagt gaccctacca ccacgggtgt cagaagtcat   2100

tggtacagtc tcaaatacca cagctcagaa tgcatcatct tcaacctggg acaaatgcgt   2160

tgaagaaagg gatgccacaa atagatcccc cacccagata gtaaagatga aaacaaatga   2220

gacagttgcc caagaagcat atgaatctga agtccagccc ctggaccagg tggctgctga   2280

agaagtagaa ttgccaggga aagaggatca gtctgtctca agcagtcaga gtaaggctgt   2340

agcttctgga cagactcaga caggagcagt tacccatgac ccccctcagg attccgttcc   2400

tgtcagttca gtctctctta tcccaccacc accgcctccg aaaaatgttg cccgaatgtt   2460

ggcgctagca ttagctgagt ccgcacagca agcctcaact cagtcattga agagaccagg   2520

gacctctcag gctgggtata caaattatgg agacatagcg gtggctacaa ctgaagataa   2580

tctgtccagt tcttactctg cagttgctct agataaggcc tatttccaaa ccgatcgacc   2640

agcagagcag ttccacctcc agaataatgc accaggaaac tgtgaccatc ctctaccaga   2700

gacaacagct actggggatc ctacccattc caacacaact gaatctgggg agcaacatca   2760

ccaagtagac ttaacaggga atcagccaca tcaagcatat ttatctgggg acccagaaaa   2820

ggccagaatt acttcagttc ccttagactc agagaagtct gatgatcatg taagtttccc   2880

tgaagaccag tctgggaaga acagtatgcc aactgtctcc ttcttggatc aggaccagtc   2940

tccaccccgt ttctacagtg gagatcagcc tccttcttat cttggtgcaa gtgtggataa   3000

actccatcac cctttagaat ttgcagacaa atctcccaca cctcctaatt tacctagcga   3060

taaaatctac cctccttctg ggtcccccga agagaatacc agcacagcca ccatgactta   3120

catgacaact actccagcaa cagcccaaat gagcaccaag gaagccagct gggatgtggc   3180

tgaacaaccc accactgctg attttgctgc tgccacactt cagcgcacgc acagaactaa   3240

tcgtcccctt ccccctccgc cttcccagag atctgcagag cagccaccag ttgtggggca   3300

ggtacaagca gcaaccaata taggattaaa taattcccac aaggttcaag gagtagttcc   3360

agttccagag aggccacctg aacctcgagc catggatgac cctgcgtctg ccttcatcag   3420

tgacagtggt gctgctgctg ctcagtgtcc catggctaca gctgtccagc caggcctgcc   3480

tgagaaagtg cgggacggtg cccgggtccc gctgctgcac ctgcgcgccg agtctgtccc   3540

tgcgcatccc tgtggctttc ctgcaccact gccccccacc aggatgatgg agagtaagat   3600

gattgctgcc atacactcca gcagtgcaga tgccaccagc agttcaaatt atcattcctt   3660

tgtcactgct tcatccacct ctgtggacga tgcattgcct ttaccacttc ctgtcccaca   3720

acctaagcat gcttctcaga aaacagttta ctcctccttt gctaggcccg atgtcaccac   3780

tgaacccttt ggtccagata actgtttgca tttcaatatg actccaaact gccagtaccg   3840

tccccagagt gtacctcccc atcacaataa attggagcag caccaagtgt atggtgccag   3900

gtcagagcca ccagcctcca tgggtcttcg ttataacaca tatgtggccc caggaagaaa   3960

cgcatctgga caccactcca agccatgcag ccgggtcgag tatgtgtctt ctttgagctc   4020

ctctgtcagg aatacctgtt accccgaaga cattccaccg taccctacca tccggagagt   4080

gcagtctctc catgctccgc cgtcttccat gattcgctct gttcccattt cacggacaga   4140

agttccccca gatgatgagc cagcctactg cccaagacct ctgtaccaat ataagccata   4200

tcagtcctcc caggcccgct cagattatca tgtcactcag cttcagcctt actttgagaa   4260

tggccgggtc cactacaggt atagcccata ttccagttct tctagttcct attacagtcc   4320

agatggggcc ctgtgtgatg tggatgccta tggcacagtc cagttgagac cccttcaccg   4380

ccttcccaat cgagactttg ctttctacaa tcctaggctg caaggaaaga gcttgtacag   4440

ttatgctggt ttggctccac gtccccgggc caacgtgact ggctatttct ctcccaacga   4500

ccataatgta gtcagcatgc ctccggctgc tgatgtgaag cacacctaca cctcatggga   4560

tcttgaggac atggaaaaat accgcatgca gtccatccgg agagagagcc gtgctcggca   4620

gaaggtgaaa gggcctgtca tgtcccaata tgataacatg accccggcgg tgcaggacga   4680

cttgggtggg atctatgtca tccatctgcg tagtaaatca gatcctggga aaactggact   4740

tctctcagtg gcagaaggaa aggagagccg ccatgcagcc aaggccatca gtcccgaggg   4800

agaggaccgc ttctatagga ggcatcccga ggcagagatg gacagagccc accatcacgg   4860

aggccatggt agcacgcagc cggagaagcc atccctgcct cagaagcaga gcagcctgag   4920

gagcaggaag cttcctgaca tgggctgcag tcttcctgag cacagggcac accaagaagc   4980

aagccatagg cagttctgtg agtcaaagaa tgggccccct tatccccagg gagctggcca   5040

gttagattat gggtccaaag ggattccaga cacttctgag ccagtcagct accacaactc   5100

tggagtaaaa tatgctgcat ccgggcaaga atctttaaga ctgaaccaca aagaggtaag   5160

gctctccaaa gagatggagc gaccctgggt taggcagcct tctgccccag agaaacactc   5220

cagagactgc tacaaggagg aagaacacct cactcagtca atcgtcccac cccctaaacc   5280

agagaggagt catagcctca aactccatca tacccagaac gtggagaggg accccagtgt   5340

gctgtaccag taccaaccac acggcaagcg ccagagcagt gtgactgttg tgtcccagta   5400

tgataacctg gaagattacc actccctgcc tcagcaccag cgaggagtct ttggaggggg   5460

cggcatgggg acgtatgtgc cccctggctt tccccatcca cagagcagga cctatgctac   5520

agcgttgggt caaggggcct tcctgcccgc agagttgtcc ttgcagcatc ctgaaacaca   5580

gatccatgca gaatgagccc tgcgagcaat agagttgaag cagcctctgc tggacagtgg   5640

actgttctat ttttttcaat aaccaaaaag attaaacaaa aaatactata aaacccctga   5700

ccacatttaa aaaatgataa taaaagtaaa caaatcagca tctttttccc cttccctgct   5760

tcattacccc ctcttccatc tatagacttt gtcatttttg tctttagaaa agatctgaag   5820

gatggtaaag ccccgtgctg aaacccagta gagaaacctg tctcaggaca cacttgccat   5880

ctagggctag cttgaaagag cctgaggact gcctttaact gaatttgaat tcagcattgt   5940

cctttcttct tagtatttgc tgcataattg agagcagttc acatcgattt cctggtaggc   6000

gtctgcattc cctgttgtgt tcctgcttct ccttcagtag ctgcacaact tgcgcagatc   6060

gacacactgt tgtcacttca ttctccccgt ctgagaagga tcttgtgttc agttagagtc   6120

gtggaaaaat ccctgatcct tcaaggtcag tcagacagtt ggcaacatta taattaaaaa   6180

taagaaatta agactttaaa ttaaacattt ggtagagtca tcataaaaca ccagaccact   6240

tagactcagg ctgaaccata ctctttctat tcttattttt catccttgtt cctcacggtt   6300

cagtgaacag gctcatatca tgacagaatg gacttttaaa agttagtact taaggaaact   6360

tctttaggtg gaagaaagta aagttcttat tgtcagtgaa ctttattagc accagaaatc   6420

tctattgatg cttttaatgc attgcctgcc ttcaggtttt cttcttaccc cacccctcaa   6480

taagatttgg tgaattgtaa ttctagtaaa acatgtcata ccattggttt tcctaaatta   6540

tcaactttct ttcattaaaa aaaaaaaaaa aaaaaaaagc ccagcatggt ttgactggat   6600

agacacgcat aatttattat gaatataaat ttccatgttt gtttctgttc ctaaaccaga   6660

gtacgaggtc cctgggaatt taagtagcta cgcattatct attattagac tgcaagttcc   6720

tgcaataact gcttagttca cagccccgtt tcaccagtgg agttctgggc agttattgct   6780

gtcctaaggc attactgtcg tttgcttact ctatacttgt gtggtcacag tcttcttgta   6840

attaccatct acaccagcat ttcaggtata gctctttata actctggaga catgtaaaac   6900

atgtttaaca cccacgagtt ttgaaagttg cattccttat tagagtagga actctctagc   6960

ccaactccat tctatgttct cagctccctc caccccccaa aatacatcag actagcaagg   7020

cagtcctatg tttacaaaac gagtttagat tgtcatttca ttccataact cttaataata   7080

ctcaagtttt atacattcac gtattttaaa tgctcggtct gtagaagaca ctaggagaat   7140

tgcattccaa ttactggatg gttgctgctc tggcttttta gaacttgaaa ttaattttta   7200

tttagagcaa aggaggaaat cttttaagag gctaaaatca tgctgctatt attgctgtga   7260

aattgtataa agattaggat tcatgccagt ttttatttta aaaaataatg tgcattttaa   7320

gggtttatat ttagaaaaaa ataaaatgtt tcaagaacaa cacattgata tgtggaaata   7380

ttctataagg ttttcttttg ttcccttaga attcattgga gggatgcagt aaaaactgta   7440

gtagaaacct tgaaacaccc atatgtgaaa aggtctgtgg aaattgaggc ctctacatta   7500

aaagtgcaga accaactgtt ttacagtcaa agtgctagga aacctgatag gatacttccc   7560

tttggcacaa aaacaccctg ggtgctacat acaggagtat gacctttggt gaatatgtgg   7620

cactaatttt ttttacctta atcatattct tgtcaagtag gcaacccatt gccccttgga   7680

gaccacacca gccctgtaag ttctcaccag cagcatggag attaggaaga ggggctgctg   7740

tgaccaggag atacacacgg ctttaagtaa ctgagagcct aaagaaagta acccagggag   7800

tccggtccag ttttaatatt tgtggatttg ttgtcacaca cattgtttag tcctgaaact   7860

aaaacctatt ttataaatag tagggttaat tcctcgaaac aatttcttta ttaataaatg   7920

tcctgtgggt ttagaaatat caggtaaata tttgaataca gaatgatgat tgcaattact   7980

gttacaagcg tgaaacacaa acttcagatc aaatctagag ttgcttcatt taatgcatgc   8040

tagcaacagc cttaactttg gattcagtta tttgaaacac ttttccggca tctttccctt   8100

tctaatgttg tggggtggaa accggatggc aaatcactgt gagccggata cctcagcaca   8160

gtccaccttg tgtgtgactt cacaaatggg ggacttcaca aatggggtaa ctgaatgtta   8220

ttactttcaa attttgacat ggagcattat gatcaaggaa atggagctgc cttatacatt   8280

aaacccgtga tttaatccta ttgacatttt catagccatg cctccagatt ttatcttttt   8340

ggcaaaattc tgattccaca gtttggtctg attgaaataa atattccctg gacgtctggc   8400

taaaaatttt gctaacaatc ccagaggtgc cattttctta ttaataaatt tcattggagc   8460

cttatttctt actatattca atttcgtttc aaacctgcaa gtccctggga tggtcccacg   8520

actagggcct gcacatttct tacaatggca aagcattttt taaaatttag ggtcaggttg   8580

aaaaattcta ggactaattc tgtagagagg agggactgtt aactaacgtg agtggggacg   8640

gaggagtagg ttaccacatt tggagcagta atagatgcaa acgatgtaaa tttgaaattt   8700

gcccctttag ttaaagaagg agcctgcaaa gtccatttct ctgttttcag ccctgtcagt   8760

cacccattta ggatgttggc aaagtactgc ttgagcagaa tgtgtaagaa agtaataatg   8820

aaagcaaaag tatgtcagac agttacttct tccacatggt tagaggcatg tgattttcag   8880

cactgtgtgt tacagaaatg tcaggaatgg tgtattataa cgtgtgcaag ataatgtcag   8940

tgtgcacaga gggtcttttt tccttatctg attagtactg ttaatgttca aagaataaaa   9000

atggttttac agtttagatt ctgagatagc aaaacctgat ttttcaacca tgacctgcat   9060

gagagaagca tcctaggaag tcttagatca tacttttgag tttttaattt taatttatat   9120

agtgtttttt tatgtcttaa tatttttgtg aactggtgta aattgttaat gcatataagc   9180

ttgtgtattt ttgtaaatag ttttgtgatt tatttcttgc cccatatgta aatatttaga   9240

gtctcatttc ttgcaaactt atttgaagct gagttgtggg tttgggtttt gtttgtttct   9300

ttggttgcag ggtggggtgg ggggtggcag gggagggagg aagggatttt tgtacctgga   9360

gatggagata tcttgtggtt taaagcaaat gtcccactga aagtgattca aatatcaaca   9420

gaattatttc aggttaaaac aga                                           9443


<210>  714
<211>  4035
<212>  DNA
<213>  Human

<400>  714
aacaacaacc accacaaact ccgaccgtcc tttccaggcc ctttccctct ataaacctgc     60

cgttttctgt ctcccaagtc atcccagttt agaactgctc caggaaataa tgaatgaaca    120

gagagagcct agtttgttta tttatttaca atccactagt ctaatctagt ttagatccag    180

cggcaatttt tggggtgcca aggaggaaag aaggagatgg cagtgcgggg acagggcaga    240

gcctgggcca aaggaagcca cacccagttc ttgccctgcc ctgcccgaca caggcaacgt    300

gaccccaagc gacagccagc tgatgcttgc ttctccgagc ccggcggtca gcagccggaa    360

gtagcccgcc cgggggcggg gaaaggtgcc ttaaggagga gctaggggcg tgcggccaat    420

tgcaagcgac tgtcctagcg aagagggcgg aagaggagag atccagttcc ggacgcggcc    480

gccgccgtcg ccgccatctg tcacctccac tccggcatca gcagccagtc gcccgtgtcc    540

cgcctgtctc ctcggcggag cctgctgccc gtcctgccac ctctctgctc tgttcttgtc    600

tctgccttca ttcccgaatg gatctggtag gagtggcatc gcctgagccc gggacggcag    660

cggcctgggg acccagcaag tgtccatggg ctattcctca aaatacaata tcttgttctt    720

tggctgatgt aatgagtgaa cagctggcca aagaattgca gttagaagaa gaagctgccg    780

tttttcctga agttgctgtt gctgaaggac catttattac tggagaaaac attgatactt    840

ccagtgacct tatgctggct cagatgctac agatggaata tgacagagaa tatgatgcac    900

agcttaggcg tgaagaaaaa aaattcaatg gagatagcaa agtttccatt tcctttgaaa    960

attatcgaaa agtgcatcct tatgaagaca gcgatagctc tgaagatgag gttgactggc   1020

aggatactcg tgatgatccc tacagaccag caaaaccggt tcccactcct aaaaagggct   1080

ttattggaaa aggaaaagat atcaccacca aacatgatga agtagtatgt gggagaaaga   1140

acacagcaag aatggaaaat tttgcacctg agtttcaggt aggagatgga attggaatgg   1200

atttaaaact atcaaaccat gttttcaatg ctttaaaaca acatgcctac tcagaagaac   1260

gtcgaagtgc ccgcctacat gagaaaaagg agcattctac agcagaaaaa gcagttgatc   1320

ctaagacacg tttacttatg tataaaatgg tcaactctgg aatgttggag acaatcactg   1380

gctgtattag tacaggaaag gagtctgttg tctttcatgc atatggaggg agcatggagg   1440

atgaaaagga agatagtaaa gttataccta cagaatgtgc catcaaggta tttaaaacaa   1500

cccttaatga atttaagaat cgtgacaaat atattaaaga tgatttcagg tttaaagatc   1560

gcttcagtaa actaaatcca cgtaagatca tccgcatgtg ggcagaaaaa gaaatgcaca   1620

atctcgcaag aatgcagaga gctggaattc cttgtccaac agttgtacta ctgaagaaac   1680

acattttagt tatgtctttt attggccatg atcaagttcc agcccctaaa ttaaaagaag   1740

taaagctcaa tagtgaagaa atgaaagaag cctactatca aactcttcat ttgatgcggc   1800

agttatatca tgaatgtacg cttgtccatg ctgacctcag tgagtataac atgctgtggc   1860

atgctggaaa ggtctggttg atcgatgtca gtcagtcagt agaacctacc caccctcacg   1920

gcctggagtt cttgttccgg gactgcagga atgtctcgca gtttttccag aaaggaggag   1980

tcaaggaagc ccttagtgaa cgagaactct tcaatgctgt ttcaggctta aacatcacag   2040

cagataatga agctgatttt ttagctgaga tagaagcttt ggagaaaatg aatgaagatc   2100

acgttcagaa gaatggaagg aaagctgctt catttttgaa agatgatgga gacccaccac   2160

tactatatga tgaatagcac taatacccac tgcttcagtg ttaacacagc agtgattgtc   2220

agctgccaat agcaaatgaa gttatgggtg acttgaaata ccaaaacctg aggagtgggc   2280

aatggtgctt ctgtgctttt cccccttgta acccatgtgc cagatgtgtg gaatttttag   2340

ctcagcattg agagaataaa atgtcactac ctctcatctt atgaacagga taatataatt   2400

ctttaacagc tataggttat ctggctgaag tagacctaat tttatgtgac ttgtggtgta   2460

aaatgtcttg atgataattt ttaaaacttg ggtaacactt ccaaatatgg gaggaaagga   2520

cagatgtgtt tacaagggag gattttacaa catacttgct ttattcacct ccctgttttg   2580

tgttgcgtct ttccttgaat attttattgg cccagagtta gcctttctca attatgtttc   2640

cagactgtgg ccgtgattct aaaggaaaat gtgtgctctt tagtgggtag aacaaatgga   2700

aatttggttt cagaatggct gacagaaatc gacataagtc atgtaatttt tgttgatata   2760

tcatgaaaat gaacagaatt ctttttccat acttatatct aagaaaaggc atcataggtt   2820

tctgaaagag ataactatat aacagctttt taactatcca gtcaactttc agcttttcta   2880

catttaggta aaatggttag gatataactc atggtgtggc taatctacat ttatcaataa   2940

aatgtaaatt atctgaaagg acagaatata agatttaacc atgtttgacg tattttaatt   3000

tagttaatga agcaaaattc agtttatatt tcactagaac tgtgtacttg attgattttc   3060

agagaaatat cacaaattag aaatattaaa tctaaggatg aaaggtatat ataaaacaat   3120

ttgggggcca ggcacgatgg ctcaaacctg taatcccagc actttgggag accaaggcgg   3180

gtggatcact tgaggtcagg agttcaagac cagcctgggc aacatggcga aaccctgtct   3240

ctactaaaaa tacaaaaatt agccgggtgt ggtggcactt ctctgtaatc tcagcttctc   3300

aggaggctga gacaggagaa tcgcttgaac ccgggaggca gaggttgcag tgagctgaga   3360

tcatgccact gcactccggc ctaggtgaca gagggaaact ccatctccag gaaaaaaaaa   3420

aaaaaaccca atttggatac caaattaatc aactaatttg agctatctgg ccttactctt   3480

agtagttttt agtacgtgct ggacaccact tttaaaaagc aatcactgtg ctagaaaagt   3540

atattggctt tgttaggatt aaagttcatt aacttcaatg taatcatgcc tcctattact   3600

gaagtcagat tggaaccact aaagatccaa actttctgtc tggtaataga aagtaaaaat   3660

ctagacatca tttacatttg agaaagctgt ttttaacatt attttaaaat gccaaatatg   3720

ttctttctag aaaaatattt atttttgttt ttgttggata gcttttaatt acatttcaga   3780

gaggtgtaat tttgggtaga tgctcattac atttttgaaa ggtttatgat tccaaaataa   3840

agatttatat gactggtgat actggcttta cagaaatttc agagaactaa tttttaaaat   3900

ctttagcatt taaaactttt tttgttttgt tttctgacat attctgacaa agagcagcaa   3960

accactgctg tgtggcattc ttggagtgtg ctgtgaatgt gctttttaag aaattaaaaa   4020

gagatcattt taaaa                                                    4035


<210>  715
<211>  3185
<212>  DNA
<213>  Human

<400>  715
ggagctgtgg gggccagacg aacccgagcg ctcccaccga gctgcctgcc atggggctgg     60

ggctgctgct cccgctgctg ctgctctgga ctcgggggac tcaggggtcc gagctggacc    120

ccaaagggca gcacgtctgt gtggccagca gcccctctgc tgagctgcag tgctgcgcag    180

gctggaggca gaaggatcaa gaatgcacca tccccatctg tgaggggccg gacgcctgcc    240

agaaagacga ggtgtgtgtg aagccgggcc tctgtcgatg caagcctgga ttctttgggg    300

cccactgcag ctcccgctgc ccgggccagt actggggccc cgactgccgt gagagctgcc    360

cctgccaccc gcacggccag tgcgagccag ccacgggcgc gtgccagtgc caggccgacc    420

gctggggagc ccgctgcgag ttcccgtgcg cctgcggccc ccacgggcgc tgcgaccccg    480

cgaccggcgt gtgccactgc gaacccggct ggtggtcgtc cacgtgccgc cgcccgtgcc    540

agtgcaacac cgcggcggcg cgctgcgagc aggccacggg cgcctgcgtg tgcaagccgg    600

gctggtgggg gcgccgctgc agcttccgct gcaactgcca cggctccccg tgcgagcagg    660

actccggccg ctgcgcctgc cggccgggct ggtggggtcc cgaatgccag cagcagtgcg    720

agtgtgtgcg gggccgctgc agcgccgcct ccggcgagtg cacctgcccg cccggcttcc    780

gcggagcgcg ctgcgagctg ccctgcccgg caggcagcca cggggtgcag tgcgcacaca    840

gctgtggccg ctgcaaacac aatgagccgt gctctccaga cacaggcagc tgtgagtcct    900

gcgagccggg ctggaacggg acccagtgcc agcagccctg cctgcctggc acctttggcg    960

agagctgcga acagcagtgc cctcactgcc gacatgggga ggcctgtgag ccagatactg   1020

gccactgtca gcgctgctct ggcagtcggg acactgccct catcgcgggc agccttgtgc   1080

ctctgctgct gctcttcctg ggccttgcct gctgtgcctg ctgctgctgg gccccccgat   1140

cagacctcaa ggacaggcca gcgagagatg gagctaccgt gtccaggatg aagctgcagg   1200

tctgggggac actgaccagc ttgggctcca cgctgccctg ccgttccctc agctcccaca   1260

agctaccctg ggtgacagtc tcacatcacg acccggaggt ccccttcaac cacagcttca   1320

tcgagccgcc ctctgccggc tgggccactg atgactcctt ctcatccgat cctgagtctg   1380

gagaggcaga tgaggttcct gcctactgtg tgccacccca agaagggatg gtccctgtgg   1440

cccaggcagg gtcgtcagag gccagcctgg ctgcaggtgc tttcccgccc cctgaggacg   1500

cctccacgcc attcgccatc ccgcgcacct ccagcctagc tcgggccaag cggccatcgg   1560

tctccttcgc ggaaggtacc aagtttgcac cacagagtcg ccgaagctca ggggagctct   1620

ccagcccgct ccgaaagccc aagaggctct cccggggggc gcagtcgggt cctgagggcc   1680

gggaagccga agagtccaca ggcccagagg aagcagaagc ccccgagtcc tttccggcgg   1740

ctgccagtcc cggggattca gccactggcc accggcggcc cccacttggt ggccggacag   1800

tggctgagca cgtggaagcc attgagggca gcgtccagga gagctcgggc cctgtgacca   1860

cgatctacat gctggcaggg aagccccgcg gatccgaagg ccctgtccgc tctgtcttcc   1920

gccattttgg tagcttccag aaaggccagg cggaagccaa ggtcaagagg gccatcccta   1980

agcctccgcg ccaggccctg aatcggaaaa agggcagccc tggccttgcc tctggctctg   2040

tcggccagag ccccaactca gccccaaaag ctgggcttcc tggggccaca gggcctatgg   2100

cagtcagacc agaggaagcg gtccgggggc tgggggctgg caccgagagt tcaaggagag   2160

cccaggagcc agtctctggc tgtggctccc cagaacagga tccccagaag caggctgaag   2220

aggaaaggca ggaggaacct gagtatgaga atgttgtacc catctccagg ccaccagaac   2280

cctgatgacc ttgaatttgg ggagtgggga gagtggatgg actagactgt gctgtgtgct   2340

ggaaaatgat cccggggcca ggacagacaa accagagcct ctgcgcctcc acagggaaaa   2400

ggcaaggctt ccaggccagt tggcccaggc ccctggcagt gctcccggag gggcccagga   2460

aggcctgggc agagaccctg taggatgggg tcaggaaggg ttgcctgcag ggacttttgc   2520

tctgctgtcc tggaccctgt gtgcctcata agggctattc tttctttcac gtgcaaaaca   2580

tttttctgaa atagcaaaca acctacatgt ttgctgataa aagattggct aaacaaattt   2640

tttttttttt ttttgagaca gaatctccct ctgtccccca ggctggagtg cagtggtgcg   2700

atctcggctc actgcaagct ctgcctcccg ggttcacgcc cttctcctgc ctcagcctcc   2760

cgagtagctg ggactacagg tgccctccac cacgcttggc taattttttt gtatatttaa   2820

tagagacagg gtttcaccat gttagccagg atggtctcga tctcctgacc tcgtgatcca   2880

cctgcctcgg cctcccaaag tgctgggatg acaggcatga gccaccacgc ctggtctatg   2940

aactttttaa aaaggatgta tgtgtataaa aacagattca agggaaaggc actaaatggt   3000

tttttcctct ggaagatgag attgtaggtg atatttattt tcttctgaaa cttttgtata   3060

gtttgcaaat tttctacagt gaacattctt ttttactttt gttactagat tgaatttgat   3120

aaagtataat aaaaagcaat gatctttgtt aaaaaaataa aaagtactaa cattacagac   3180

atgta                                                               3185


<210>  716
<211>  5201
<212>  DNA
<213>  Human

<400>  716
ccgcaccatg ctcaagtgca tcccgctgtg gcgctgcaac cggcacgtgg agtcggtgga     60

caagcggcac tgttcgctgc aggccgtgcc ggaggagatc taccgctaca gccgcagcct    120

ggaggagctg ctgctcgacg ccaaccagct gcgcgagctg cccaagcctt ttttccggct    180

gctgaacttg cgcaagctgg gcctgagcga caacgagatc cagcggttgc ctcccgaggt    240

ggccaacttc atgcagctgg tggagctgga cgtgtcccgg aacgatatcc ctgagatccc    300

ggagagcatc aagttctgca aggctctgga gatcgcggac ttcagcggga accccctctc    360

caggctccct gatggcttca ctcagctgcg cagcctggct cacctggccc tgaatgatgt    420

gtctctgcag gcactgcccg gggacgtggg caacctcgcc aacctggtga ccctggagct    480

ccgggagaac ctgctcaagt ccctgccagc gtccctgtca tttctggtca agctggaaca    540

gctggatctg ggaggcaacg atctggaagt gctgccagac actctggggg ctctgcccaa    600

tcttcgggag ctgtggcttg accggaacca gctgtcagca ctgcccccgg agctcgggaa    660

cctgcggcgc ctggtgtgcc tggacgtgtc ggaaaaccgg ctggaggagc tgcctgctga    720

gctcggcggg ctggtgctgc tcactgacct gctgctgtcc cagaacctgc tgcggaggct    780

gcccgacggc atcggtcagc tgaagcagct atccatccta aaggtagacc agaatcggct    840

gtgcgaggtg actgaggcca tcggggactg tgagaacctc tctgagctga tcctcacgga    900

gaacctgctg atggccctgc cccgctccct gggaaagctg actaagctga ccaacctcaa    960

cgtggaccgg aaccacctcg aggcgctgcc gcccgagatc gggggctgtg tggcactcag   1020

cgtcctctcc ttgagggaca accgcctggc cgtcctgcca ccagagctgg cccacacgac   1080

agagctgcac gtgctggacg tggcggggaa ccgcctgcag agtctgccgt tcgcgctcac   1140

ccacctcaat ctcaaggccc tgtggctggc agagaaccag gcgcagccca tgctccggtt   1200

ccagacggag gatgatgccc ggaccggcga gaaggtgctc acctgctact tgctgcccca   1260

gcagccccca cccagcctcg aggatgctgg gcagcagggg agcctctcgg agacctggag   1320

cgatgccccg ccgagccgcg tcagcgtcat ccagttcctg gaggccccca taggtgatga   1380

ggacgctgag gaagctgcag ctgagaagcg gggcctacag cgccgggcca cacctcaccc   1440

cagcgagctc aaggtgatga agaggagcat cgaggggcgg cggagcgagg cctgcccttg   1500

ccagccagac tctgggtcgc ccttgcctgc agaggaggag aagcggctga gtgccgagtc   1560

tggcctgagt gaagactctc gcccatctgc cagcacagtc tctgaggctg agcccgaggg   1620

cccgtcggct gaggcacagg gtgggagcca gcaggaagcc acgactgctg gcggggagga   1680

agacgccgaa gaggactacc aggagcccac ggtgcatttc gcagaggacg cactgctgcc   1740

cggggatgac agggagatcg aggaggggca gcctgaggcc ccctggaccc tgccaggcgg   1800

gaggcagcgg ctcatccgca aggacacacc tcactacaaa aagcacttca agatctccaa   1860

gctgccccag cccgaggccg ttgtggctct gctgcagggc atgcagcctg atggggaggg   1920

ccctgtggct cccgggggct ggcacaatgg cccccacgca ccctgggctc ctcgggccca   1980

gaaggaggag gaggaggagg aagagggtag tcctcaggag gaggaggaag aggaggagga   2040

ggaaaacagg gctgaagagg aagaggccag cactgaggag gaggacaagg agggggccgt   2100

ggtttctgcg ccctctgtca agggagtgtc gtttgaccag gccaataacc tgctgataga   2160

gcctgctcgc attgaggagg aagagctgac cctcaccatc ctgcggcaga ctgggggcct   2220

gggcatcagc attgcgggcg gcaagggctc cacaccctat aagggggacg acgagggcat   2280

attcatctct cgggtgtccg aggaaggccc tgcggcccgg gctggagtcc gtgtgggtga   2340

caagctcctg gaggtgaatg gtgtggctct gcagggcgcc gagcaccacg aggccgtgga   2400

ggcgctccgg ggggccggca ctgccgtgca gatgcgagtg tggcgggagc gcatggtgga   2460

gcctgagaac gcggtcacca tcacgccgct gcggcccgag gatgattaca gcccccgaga   2520

gcggcgggga ggggggctgc gcctgcccct gctcccgcct gagagccccg ggcccctccg   2580

tcagcgccac gtggcctgcc tggcacgcag cgagaggggg ctgggcttca gcattgctgg   2640

tgggaaaggc tccacaccct acagggctgg tgatgcgggc atcttcgtct cccgcattgc   2700

cgagggcggt gctgctcacc gcgcgggcac actgcaggtt ggcgaccgcg tcctctctat   2760

taatggagtg gacgtgactg aggccaggca tgaccacgcc gtctccctgc tgaccgctgc   2820

ctcccccacc atcgccctgc tgttggagcg ggaggctggg ggccctcttc ctcccagccc   2880

tctgccacat tcctcacccc ccaccgctgc tgttgccacc accagcataa ccactgccac   2940

ccccggggtg cctgggttgc cgagcctggc ccccagcctg ctggctgccg cgttggaagg   3000

gccataccca gtggaggaga tccgtctgcc aagagctggg ggccctctgg ggcttagtat   3060

tgtcggaggc tccgaccatt ccagccaccc gtttggtgtc caggagcctg gtgtgttcat   3120

ctccaaggtg ctcccgcggg gcctggccgc tcgcagcggc ctgcgggttg gggaccgcat   3180

cctggcagtg aacgggcaag acgtgcggga tgccacgcac caagaagcag tcagtgccct   3240

gctccggccc tgcctggagc tgtcgctgct ggtgcggagg gacccggcac ccccgggcct   3300

acgggaactg tgcatccaga aggcacctgg ggagaggctg ggcatcagca tccgcggggg   3360

tgccaggggc cacgctggca acccccgcga ccccacagac gagggcatct tcatctccaa   3420

ggtgagcccc acgggggcag ccgggcgcga cggtcggctg cgtgtgggtt tgcggctgtt   3480

ggaggtgaac cagcagagcc tgctgggcct gacgcacggc gaggcggtgc agctgctccg   3540

cagtgtgggc gacaccctca ccgtgctggt ctgtgacggc ttcgaggcca gcaccgacgc   3600

agccctggag gtgtccccag gtgtcattgc caaccccttt gcggcaggca tcggccaccg   3660

gaacagcctg gagagcatct cttccatcga ccgggagctg agccctgagg gcccaggcaa   3720

ggagaaggag ctgcctggac agaccctgca ctgggggccc gaggccacag aagccgcagg   3780

tcggggtctg cagcccctga agctggacta ccgcgccctg gccgccgtgc ccagcgctgg   3840

cagcgtgcag agggtaccgt ctggagcagc tggagggaag atggctgaat ctccctgctc   3900

ccctagtggc cagcagccgc cctccccgcc ttctccggat gagctgcccg ccaatgtgaa   3960

gcaggcctac agggccttcg cggccgtgcc cacttctcac ccgcctgagg atgcccctgc   4020

ccagcccccc acgcctgggc ctgcagcctc cccggagcag ctgtccttcc gggagcggca   4080

gaagtacttt gagctggagg tgcgcgtgcc ccaggccgag ggccccccta agcgcgtgtc   4140

cctggtgggt gctgacgacc tgcggaagat gcaggaggag gaagccagaa aactacagca   4200

gaagagagcg cagatgctgc gggaggcggc agaggctggg gccgaagcga ggctcgccct   4260

ggacggggag acgctgggcg aggaggaaca ggaggatgag cagccaccct gggccagccc   4320

gagccccacc tcaaggcaga gcccggcgtc ccccccgccc ctgggaggtg gcgccccggt   4380

gcggacggcc aaagctgaac ggcgccacca ggagcggctg cgcgtgcaga gtccggagcc   4440

accggcaccc gagcgtgccc tgtcccctgc cgagctccgg gccctggagg ccgagaagcg   4500

tgcgctgtgg agggcagcca ggatgaagtc attggaacag gacgctctcc gagcacagat   4560

ggtcctcagc aggtcccagg aaggccgggg cacgcggggg cccctggagc gactggccga   4620

ggccccttcc cctgcgccca ccccgtcgcc cacccctgtg gaagacctcg gcccccagac   4680

cagcacctcc ccgggacgcc tgtcaccgga ctttgctgag gagttgaggt ccctggaacc   4740

atctcccagc cctggcccgc aggaggagga tggagaagtg gctctggtgc ttctgggcag   4800

gccctcaccc ggcgctgtgg gccctgaaga tgtggcactg tgcagcagcc gccgccccgt   4860

aaggcctggg cgccgtggcc tgggccctgt gccctcctag aggagcaggc acctccccca   4920

gacttggggt gggggccctg ccagctccag caccaccctt gccccaagtc ttttaacctg   4980

ggtgttagca ttttaaagag accccacagg agttctggcc tgtgactaac taactgcccc   5040

accccagccg agacctcggc gagactgtaa ctagtgatgt ttgtacaacc aaagactcta   5100

ttttgtggtt taaggagaat aaagttgact acattttacc tccaaaaaaa aaaaaaaaaa   5160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a                       5201


<210>  717
<211>  1147
<212>  DNA
<213>  Human

<400>  717
gtggctttgc cctttggcct ttgctggctg tgtggcggct ccgcggttcg caggtcgttc     60

gctgagcgtc tctgcttagc cgcggtcatg agccggcaca gccggctgca gaggcaggtt    120

ctgagcctgt accgcgatct gctgcgcgcc gggcgtggga agccgggcgc cgaggcgcga    180

gtgcgggcag agttccggca gcatgcgggc ctgccgcggt ccgacgtgct gcgcatcgag    240

tacctgtacc gccgcgggcg gcgccagctg cagctgctac gctcgggcca cgccaccgcc    300

atgggcgcct tcgtacgccc gcgggccccg accggggagc ctggcggcgt gggttcccag    360

cctgacgacg gcgacagtcc aaggaacccc cacgacagca cgggggcacc ggagacccgc    420

cccgacggac ggtgacaggc gaagagccga actcgctcga tggcgtggtg gagccaggag    480

gctcgcctga ctgcatgggg ggactgggga acccgcctaa ggtgagaggt cttaagagac    540

tagcttgacg aattggggat gtcagagact cctccttggc gacgcagggg gcctagagag    600

ccccgtgatg gacggcaagg gaggcccgcc ttttccgatg cttggagaca ggtcggtgct    660

cctcccccat gagggcttgg ggcggcctgg gacgctggcg ggctggacag tgtcaagcca    720

agagctactt gcccgaaggt acggggagcc aggacgaccc ccggtggaca gggagagcct    780

gagacgccct tctcttgacc cctgagaaca tacccacttc tggctcctca aggagtctcc    840

cctctcctgt atttaactct gagaagtgca gactttttgc tgagaacgtt ttgggaaggt    900

gccctgatga gcggtgagaa gcccggaatc cccttctgga aaactttccc ccattaattg    960

tgacaagcca ggaccatgag gaaggggtag gggtctatca ccctggttga tcaactgaag   1020

acccccaaag gcccctactt gatggttttg aggggcaaca ttgactcatt tgccccttcc   1080

ctctcggaat gttggacaaa gggaataaaa ttggggatat gtctacttcc caaaaaaaaa   1140

aaaaaaa                                                             1147


<210>  718
<211>  2116
<212>  DNA
<213>  Human

<400>  718
agcattgtgg gattggatga gtctcaagat ggacaaccgg gatgttgcag gaaaggctaa     60

ccggtggttt ggggttgctc cccctaaatc tggaaaaatg aacatgaaca tccttcacca    120

ggaagagctc atcgctcaga agaaacggga aattgaagcc aaaatggaac agaaagccaa    180

gcagaatcag gtggccagcc ctcagccccc acatcctggc gaaatcacaa atgcacacaa    240

ctcttcctgc atttccaaca agtttgccaa cgatggtagc ttcttgcagc agtttctgaa    300

gttgcagaag gcacagacca gcacagacgc cccgaccagt gcgcccagcg cccctcccag    360

cacacccacc cccagcgctg ggaagaggtc cctgctcatc agcaggcgga caggcctggg    420

gctggccagc ctgccgggcc ctgtgaagag ctactcccac gccaagcagc tgcccgtggc    480

gcaccgcccg agtgtcttcc agtcccctga cgaggacgag gaggaggact atgagcagtg    540

gctggagatc aaagtttcac ccccagaggg agccgagact cggaaagtga tagagaaatt    600

ggcccgcttt gtggcagaag gaggccccga gttagaaaaa gtagctatgg aggactacaa    660

ggataaccca gcatttgcat ttttgcacga taagaatagc agggaattcc tctactacag    720

gaagaaggtg gctgagataa gaaaggaagc acagaagtcg caggcagcct ctcagaaagt    780

ttcaccccca gaggacgaag aggtcaagaa ccttgcagaa aagttggcca ggttcatagc    840

ggacgggggt cccgaggtgg aaaccattgc cctccagaac aaccgtgaga accaggcatt    900

cagctttctg tatgagccca atagccaagg gtacaagtac taccgacaga agctggagga    960

gttccggaaa gccaaggcca gctccacagg cagcttcaca gcacctgatc ccggcctgaa   1020

gcgcaagtcc cctcctgagg ccctgtcagg gtccttaccc ccagccacca cctgccccgc   1080

ctcgtccacg cctgcgccca ctatcatccc tgctccagct gcccccggga agccagcctc   1140

cgcagccacc gtgaagagga agcggaagag ccggtggggg cctgaagagg ataaggtaga   1200

gctcccacct gctgaactgg tgcagaggga cgtggatgcc tctccctcgc ctctgtcagt   1260

tcaggacctc aaggggctcg gctatgagaa ggggaagcct gtgggtctag tgggcgtcac   1320

agagctttca gacgcccaga agaagcagct gaaggagcag caggagatgc agcagatgta   1380

cgacatgatc atgcagcaca agcgggccat gcaggacatg cagctgctgt gggagaaggc   1440

agtccaacag caccagcacg gctatgacag tgatgaggag gtggacagcg agctgggcac   1500

ctgggagcac cagctgcggc gcatggagat ggataagacc agggaatggg ccgagcagct   1560

gacaaagatg ggccggggca agcacttcat cggagacttc ctgcctccag acgagctgga   1620

aaagtttatg gagaccttca aggccctgaa ggagggccgt gagcctgact actcagagta   1680

caaggagttc aagctgactg tggagaacat cggctaccag atgctgatga agatgggctg   1740

gaaggagggc gaggggctgg gctcagaggg ccagggcatc aagaacccag tgaacaaggg   1800

caccaccaca gtggacggcg ctggcttcgg cattgaccgg ccggcggagc tctccaagga   1860

ggacgacgag tatgaggcgt tccgcaagag gatgatgctg gcctaccgct tccggcccaa   1920

ccccctgaac aatcccagac ggccttacta ctgagtgttc tggaaataca tactttctga   1980

atgaccaacc gtccctggac tgtggaatgt tccggcctgc atttctgccc accccttccg   2040

ttgtcacgag tgccgtgccg tgtaataaag tcccagtgct catccaccaa aaaaaaaaaa   2100

aaaaaaaaaa aaaaaa                                                   2116


<210>  719
<211>  4298
<212>  DNA
<213>  Human

<400>  719
ggaagtgagg gagggaggac tttcgtacgc agccgcctcc cagctggaac ctcatcttta     60

gtgctcggcc gcgggcggcg taactcgggg ttccgcctcg gaatacctcc cacttctctt    120

gtctaagagg agcagtagca agctgagctc agagcgaagc tggcgagcca aggagataaa    180

gaaccctcgg tggggatgcc cagagggtgc atgctccacg cccctcgaaa ccgattctca    240

ttgctgctgc tgcaaagcaa cccgaagtgc gccacctacc cgactgaggc tgcgcaagcc    300

ccggggtctg ggcggggtgg tcctcgtgcg cgccgcgtcg ccgtggagac gagggcgggc    360

ccgcgcgaga ctggcgtcta gaggcgcgcg aagcgctgag gcgggcgtgg accgcgcggg    420

agttaagaag caggtcccgg atcgccgtat accgccgggt tttctcccaa cgtcaggccc    480

gatggctcgg cttccccagt tagaagggga agataaaaga ctttgattca tgaagaatct    540

gctcactgag aagtgtatat caagccacaa tttccatcaa aaagtgatta agcagagaat    600

ggagaagaag gttgattcca ggtattttaa ggatggtgca gttaagaaac cttattctgc    660

aaagacactg tccaacaaga agtcttctgc atcctttggg atccggaggg agttacctag    720

taccagtcat ctagtgcagt atcgtggcac acatacttgt acccgacagg gccggttaag    780

agaactgcgc atcagatgcg tggccagaaa gttcttatat ttatggattc gaatgacttt    840

tggaagagta tttccctcta aagccagatt ttactatgag cagcgattac tacggaaggt    900

cttcgaagaa tggaaagagg agtggtgggt tttccagcac gagtggaaac tctgtgttcg    960

agctgactgt cactacaggt attacctgta caacctgatg ttccagacgt ggaagaccta   1020

tgtgcgtcag cagcaggaga tgaggaacaa gtacattaga gccgaggttc atgatgcaaa   1080

gcaaaagatg cgacaggcct ggaagtcctg gttgatctac gtggttgttc gtaggaccaa   1140

acttcagatg cagactacag ctctggagtt taggcaacgg attatcttac gggtgtggtg   1200

gagcacgtgg aggcagcgac taggacaggt ccgtgtgagc cgtgccctcc atgcctctgc   1260

tttgaagcac agggccctga gcctccaggt gcaggcttgg tcacagtggc gggaacagct   1320

cctgtatgtc cagaaggaga aacaaaaggt tgtctctgca gtgaaacatc atcagcactg   1380

gcaaaaacgg agatttctaa aggcctggct tgaatacctg caagtccgca gagtgaagag   1440

acagcagaat gagatggctg agcgattcca tcatgtcact gtgctccaga tatacttctg   1500

tgactggcag caggcctggg agcggaggga gagcttgtac gctcaccatg cccaggtgga   1560

gaaactggcc aggaagatgg ccctgcggcg cgcctttact cactggaaac actacatgct   1620

gctgtgtgca gaagaagctg cccagtttga gatggcagaa gagcaccaca ggcacagcca   1680

gctgctgctg cacaggttct ggaacctctg gcggtctcag attgagcaga aaaaggaaag   1740

agagctgctc cccttactgc atgctgcctg ggaccactac agaatagcac tgctgtgcaa   1800

atgtatcgaa ttgtggctac agtatactca gaagaggcgg tacaagcagc tgctacaggc   1860

cagagcggat ggtcatttcc agcagagagc cctgcctgct gccttccaca catggaacag   1920

actctggcga tggcgccacc aggaaaatgt cctcagtgca agagcaacac gtttccacag   1980

ggagacatta gagaagcaag tattttctct ctggaggcag aagatgtttc agcatcgaga   2040

aaaccgcctg gcagagagaa tggccatcct tcacgcagag cgacagcttc tgtataggtc   2100

ttggttcatg tggcaccagc aggcagcagc acgtcaccag gagcaggagt ggcaaacagt   2160

ggcctgtgcc caccaccgcc acgggcggct caagaaagct ttctgcctct ggagggaaag   2220

tgcccaaggg ctcagaacag agaggacggg cagggtgcgg gcagcagaat tccacatggc   2280

ccagctcctg cgttgggcct ggagccagtg gagggagtgc ctggccctgc ggggagcgga   2340

gcggcagaag ctgatgcgag cagacctgca ccaccagcac agcgtgctgc acagggcgct   2400

gcaggcatgg gtgacttacc agggcagggt gcgaagcatc ctccgggagg tggcagccag   2460

ggagagccag cacaacaggc agctgctgcg cggggcatta cgtcgctgga aagagaacac   2520

catggcccga gtggatgaag ccaaaaaaac ctttcaagca agtactcatt acagaaggac   2580

catatgttcc aaggtcctgg tccagtggcg ggaagctgtg tcagtgcaga tgtattaccg   2640

acagcaggag gactgtgcca tctgggaggc ccagaaggtg ctggacaggg gctgtctgcg   2700

gacctggttt cagcgctggt gggactgcag ccggaggtca gcccagcaga gactgcagct   2760

ggagagggca gtgcaacacc accaccggca gctgctgctg gaggggctgg cccggtggaa   2820

gacgcaccat ctgcagtgtg tcaggaagag gctcctgcac aggcagagca cccaactgct   2880

ggcacagaga ctcagccgga cctgcttccg ccagtggaga caacagctgg cagccaggag   2940

gcaggagcag cgggcgacag tgcgggccct gtggttctgg gccttctcgc tgcaggcaaa   3000

ggtgtgggcc acgtggctgg cctttgtact ggaaaggagg agaaagaagg cgcggctgca   3060

gtgggcgctc caggcctacc aggggcagct cctccaggag ggtgccacgc ggctcctgcg   3120

ctttgcagcc agcatgaagg cctcccggca gcagctgcag gcccagcagc aggtccaggc   3180

ggctcacagt ctccatcgtg ccgtccgccg ctgtgccacg ctctggaaac agaaagtgct   3240

gggccggggc gggaagcctc agcccctggc agccatcgca cccagcagga aagtgacgtt   3300

tgagggtccc cttctcaacc gcattgctgc tggggctggg gatggcaccc ttgagaccaa   3360

gaggccacag gcttctcggc ctctgggagc tctgggccgc ctggctgctg aggagcccca   3420

cgccctggag ctcaacactg cccactcagc gaggaagcag ccgcgacgcc cacacttcct   3480

gttggagcct gcgcagagcc agaggcctca gaagccacag gaacatggcc taggcatggc   3540

tcagccagca gccccctccc tgacgcggcc cttcctggca gaggccccga cagcactggt   3600

cccacacagc cccctgcctg gggccctgtc aagcgcccct ggcccgaagc agcccccgac   3660

ggcaagcaca ggcccggagc tgctgctgct gcctctttcc tccttcatgc cctgcggggc   3720

ggctgcacca gccagggtgt cagcacagcg ggctactcct agggataagc ccccggtccc   3780

ctcatccctg gccagtgtcc ctgaccccca tctactcctt cctggggact tctcagccac   3840

cagggctggg cctggacttt caactgcagg cagcctggac cttgaggctg aacttgagga   3900

gatccagcag caactactgc actaccagac caccaagcag aacctctggt cctgtcggcg   3960

gcaagcgagc agcctgcgca ggtggctgga gctgaacaga gaggagccgg ggcctgagga   4020

ccaggaagta gagcagcagg tgcagaaaga gctggaacag gtggaaatgc agatccagct   4080

gctggcagag gagctccagg ctcagcgcca gcccattggc gcctgcgttg cccgcatcca   4140

ggccctgcgg caggccctgt gctagcgtgt tcgcaccagg aacgcaggtg ctgggctgtc   4200

ggggaggcct caggccacct ccaggaacag aacacagttt taagtttgat tttttttatt   4260

tcaaaatgct ttgcaattaa atgaattact gttcagaa                           4298


<210>  720
<211>  3073
<212>  DNA
<213>  Human

<400>  720
tgtgtcatcc gccattttgt gagaagcaag gtggcctcca cgtttcctga gcgtcttctt     60

cgcttttgcc tcgaccgccc cttgaccaca gacatgtctc gggatcggtt ccggagtcgt    120

ggcggtggcg gtggtggctt ccacaggcgt ggaggaggcg gcggccgcgg cggcctccac    180

gacttccgtt ctccgccgcc cggcatgggc ctcaatcaga atcgcggccc catgggtcct    240

ggcccgggcc agagcggccc taagcctccg atcccgccac cgcctccaca ccaacagcag    300

caacagccac caccgcagca gccaccgccg cagcagccgc caccgcatca gccgccgccg    360

catccacagc cgcatcagca gcagcagccg ccgccaccgc cgcaggactc ttccaagccc    420

gtcgttgctc agggacccgg ccccgctccc ggagtaggca gcgcaccacc agcctccagc    480

tcggccccgc ccgccactcc accaacctcg ggggccccgc cagggtccgg gccaggcccg    540

actccgaccc cgccgcctgc agtcacctcg gcccctcccg gggcgccgcc acccaccccg    600

ccaagcagcg gggtccctac cacacctcct caggccggag gcccgccgcc tccgcccgcg    660

gcagtcccgg gcccgggtcc agggcctaag cagggcccag gtccgggtgg tcccaaaggc    720

ggcaaaatgc ctggcgggcc gaagccaggt ggcggcccgg gcctaagtac gcctggcggc    780

caccccaagc cgccgcatcg aggcggcggg gagccccgcg ggggccgcca gcaccacccg    840

ccctaccacc agcagcatca ccaggggccc ccgcccggcg ggcccggcgg ccgcagcgag    900

gagaagatct cggactcgga ggggtttaaa gccaatttgt ctctcttgag gaggcctgga    960

gagaaaactt acacacagcg atgtcggttg tttgttggga atctacctgc tgatatcacg   1020

gaggatgaat tcaaaagact atttgctaaa tatggagaac caggagaagt ttttatcaac   1080

aaaggcaaag gattcggatt tattaagctt gaatctagag ctttggctga aattgccaaa   1140

gccgaactgg atgatacacc catgagaggt agacagcttc gagttcgctt tgccacacat   1200

gctgctgccc tttctgttcg taatctttca ccttatgttt ccaatgaact gttggaagaa   1260

gcctttagcc aatttggtcc tattgaaagg gctgttgtaa tagtggatga tcgtggaaga   1320

tctacaggga aaggcattgt tgaatttgct tctaagccag cagcaagaaa ggcatttgaa   1380

cgatgcagtg aaggtgtttt cttactgacg acaactcctc gtccagtcat tgtggaacca   1440

cttgaacaac tagatgatga agatggtctt cctgaaaaac ttgcccagaa gaatccaatg   1500

tatcaaaagg agagagaaac ccctcctcgt tttgcccagc atggcacgtt tgagtacgaa   1560

tattctcagc gatggaagtc tttggatgaa atggaaaaac agcaaaggga acaagttgaa   1620

aaaaacatga aagatgcaaa agacaaattg gaaagtgaaa tggaagatgc ctatcatgaa   1680

catcaggcaa atcttttgcg ccaagatctg atgagacgac aggaagaatt aagacgcatg   1740

gaagaacttc acaatcaaga aatgcagaaa cgtaaagaaa tgcaattgag gcaagaggag   1800

gaacgacgta gaagagagga agagatgatg attcgtcaac gtgagatgga agaacaaatg   1860

aggcgccaaa gagaggaaag ttacagccga atgggctaca tggatccacg ggaaagagac   1920

atgcgaatgg gtggcggagg agcaatgaac atgggagatc cctatggttc aggaggccag   1980

aaatttccac ctctaggagg tggtggtggc ataggttatg aagctaatcc tggcgttcca   2040

ccagcaacca tgagtggttc catgatggga agtgacatgc gtactgagcg ctttgggcag   2100

ggaggtgcgg ggcctgtggg tggacagggt cctagaggaa tggggcctgg aactccagca   2160

ggatatggta gagggagaga agagtacgaa ggcccaaaca aaaaaccccg attttagatg   2220

tgatatttag gctttcattc cagtttgttt tgtttttttg tttagatacc aatcttttaa   2280

attcttgcat tttagtaaga aagctatctt tttatggatg ttagcagttt attgacctaa   2340

tatttgtaaa tggtctgttt gggcaggtaa aattatgtaa tgcagtgttt ggaacaggag   2400

aatttttttt tcctttttat ttctttattt tttctttttt actgtataat gtccctcaag   2460

tttatggcag tgtaccttgt gccactgaat ttccaaagtg taccaatttt ttttttttta   2520

ctgtgcttca aataaataga aaaatagtta taatattgat cttcaacttt gccattcatg   2580

cttctatgca tattaggcta cgtattccac attgaaagca tgagagtgtc taggcctttg   2640

aatggcatat gccatttctg ggaaatgcat ctggaggcta agtattgctt tctacaaata   2700

attgccccct ttgttttaaa aagaagaaat gcatattgaa gtagtttgat gatttgtttg   2760

gcatatagga agcacgctgg tgctaagtat tttttaaatg gttatgtaag caaagctgaa   2820

ctgtaaatct tcaggaatat gtattaagat tgtggaatgg gtgtaagaca attggtaggg   2880

ggtgaaagtg ggtttgatta aatggatctt ttatggccct atgatctatc ctttacttga   2940

aagcttttga aaagtggaaa ggtcattttg ttgcatttcc ccatttcttg tttttaaaag   3000

accaacaaat ctcaagccct ataaatggct tgtattgaac ttttacattt gaattaaaga   3060

tgttaaacat gaa                                                      3073


<210>  721
<211>  1131
<212>  DNA
<213>  Human

<400>  721
tggagagagc ggctctcgtg gctggggagt tggatgcacc aaacctgtgt gcggctggag     60

agggaggctt ctgccagacc ctctcccggg cctgtcctgc cacccaggcc cctccccagt    120

ctcacactga gctccagatc agggaagggc cgaaaaggac gatcagggca gccgcagaag    180

gggcgccctg cgtgggacgg gtccgttgcg cgcctggtaa ccgaggggga agggaagggg    240

cctctggcgt gcggggcggt gtcgcgcagg tcccaccccg cctgcccgcg ccgcccattg    300

gtcccgagcg cgatgacttg gcgggcggag caggaaggaa accgctcccg agcacggcgg    360

cggcgtcgtc tcccggcagt gcagctgccg ctaccgccgc cctctgcccg ccggcccgtc    420

tgtctacccc cagcatgagc ggcctgcgcg tctacagcac gtcggtcacc ggctcccgcg    480

aaatcaagtc ccagcagagc gaggtgaccc gaatcctgga tgggaagcgc atccaatacc    540

agctagtgga catctcccag gacaacgccc tgagggatga gatgcgagcc ttggcaggca    600

accccaaggc caccccaccc cagattgtca acggggacca gtactgtggg gactatgagc    660

tcttcgtgga ggctgtggaa caaaacacgc tgcaggagtt cctgaagctg gcttgagtca    720

agcctgtcca gagttcccct gctggactcc atcaccacac tccccccagc cttcacctgg    780

ccatgaagga ccttttgacc aactccctgt cattcctaac ctaaccttag agtccctccc    840

ccaatgcagg ccacttctcc tccctcctct ctaaatgtag tcccctctcc tccatctaaa    900

ggcaacattc cttacccatt agtctcagaa attgtcttaa gcaacagccc caaatgctgg    960

ctgcccccag ccaagcattg gggccgccat cctgcctggc actggctgat gggcacctct   1020

gttggttcca tcagccagag ctctgccaaa ggccccgcag tccctctccc aggaggaccc   1080

tagaggcaat taaatgatgt cctgttccat tggcaaaaaa aaaaaaaaaa a            1131


<210>  722
<211>  3465
<212>  DNA
<213>  Human

<400>  722
ctgcctcagg aagcttggct tcccctccca tggggaagtg ctggaatcca ctcttgcctg     60

accctcccat aagaaacaag ggaaattcct ttacgtgagc cgccttgctc agaacaaagc    120

ttggcgtgtt tcttattcct catcaatctg acaaaatggg tatttatttg tgcctctcaa    180

gcgtgtggct tggacatgat gttccgcatc gtggaagtgg ccgtgcacca agtggaatat    240

ctgttactat agtaacagtt cctttttatt gataccagaa taaacaggaa tgcaaaggct    300

gtctcacttg ttggcacatt tcagcagcct ccgttcccag gggtttaaga accgccctct    360

agaggcagcc ctccttgcta gtctgggact tcccggtgga gtgaggaacc cagcaacacg    420

ctcctgactt cccttcccaa ggactcgacc tgagaaggac acagcagtct ctgaatttca    480

tgctctcctc tttgatgtga agaaaatgaa aagctgaaca gttgtggaac tgtggataga    540

gttagacaat aaggccgcca tgtactcgga gatccagagg gagcgggcag acattggggg    600

cctgatggcc cggccagaat acagagagtg gaatccggag ctcatcaagc ccaagaagct    660

gctgaacccc gtgaaggcct ctcggagtca ccaggagctc caccgggagc tgctcatgaa    720

ccacagaagg ggccttggtg tggacagcaa gccagagctg cagcgtgtcc tagagcaccg    780

ccggcggaac cagctcatca agaagaagaa ggaggagctg gaagccaagc ggctgcagtg    840

cccctttgag caggagctgc tgagacggca gcagaggctg aaccagctgg aaaaaccacc    900

agagaaggaa gaggatcacg cccccgagtt tattaaagtc agggaaaacc tgcggagaat    960

tgccacactg accagcgaag agagagagct gtagggccag ctgccgggct caggccactg   1020

cccaccctgg cctggacagc ctccttcagc ccttctgtac ctggcagccc tgggccccag   1080

gccctgggac gtctgtgatg ttcccacctg cttctgtaga aatgtgtcac cccagagggc   1140

ctggctctcc ctgggaggct ggggccccta agctcctagg ttttccttcc aagcacccag   1200

ccctcctgct ccaagaggga taacctgcac ccctccctgc aaggggttca gagcccagca   1260

caggagcttt ctctggcaga attgaggagg aagaggtggc cctctgactt gacaagcctt   1320

ctgttctgcc caggccttcc caccaggaat ctccgaggct ccccagggcc ccgcttctcc   1380

gtacacccca gctcctaggt ctcagagaac tcccccacct gtggttttac ctgcagccag   1440

cagagcttag cttcaaggac acctgccttc aaagccactg aggggaggaa gggcagggca   1500

gactgcagat ggccttgttg ctggcatccc ggccaggtgg gcggggacta acaaagacag   1560

ctgtttaggg tcttctcccc tcacccatgc tttcatcatc ccctccgcac agcctccccg   1620

tccaggcctt ctaaccacac ctacccaggg ctgccgcatt cctgcactca gaagtctgca   1680

gcggtgcctc acaaacttga ttgtgcataa aaatcactgg ggatcttgtt aatacagctt   1740

ctaactcaat agatctggga gatcctgcat ttctaacaag ctcccaggta aggcggaggc   1800

tgctggtgtg aggaccatgc tgtgagcagc agggcgagag tgcccagggc tgatatatat   1860

tggaaatatc acccctgaag ccatcgctgg cccccacctc ctgtggactg atgccccagg   1920

gattcccacc ccacttctgc aaccccaggt atccttcatt atccacccca tcccagactc   1980

ccaccccagg gattgcccgt gaagactttg gcctagcaaa ttgtgttggt tatgtgagtg   2040

ttgttttaat cagagatgta catgattgcc aatctgcatt tcttaccagt gtgaccacac   2100

tgttacgatg caattctagc caaaaaaaaa aaaaaaaaaa aaaaaatttt ttttttttac   2160

tttttcctag tcttatggaa agcaaatata caatgatttt cagtaggctt ctggaataga   2220

aacagtggtt tgaagacccc actgccacct ttatggactg gcccctttga gtctgaatcc   2280

ccggcctctg tcacctgaga cccaacccct agctgggcca actccagtga attcacccat   2340

ttttcttctt cagaaggcct ttcctgtgtg agacccacat attttaacct tttgctccta   2400

tcccattttt aaagaattag agaataaacc aggcctgttt cttttcccct gaaatccctg   2460

cctctggctt cctaaaccca tcatctaagg tgacagagca gtgctggaat agcatctcct   2520

ttcactttcc caaaactgcc acagatagct gccactggca tgctctttga ttcctggaag   2580

caaacgtggg actgtcggag gaaagggatt gttctggtct tactcataac tgggtggttt   2640

gagggtgact gaagtcgtgc ttttcctgtg tgtgctgcca gcacagggct gtaaatgcag   2700

atattgcgcc tgtgtgcgtg tgtataagtc aagctccaag aggctcctga atgtgactgg   2760

cgtgctgaga atgtgtttac gctgtttaat gtctgccagg tgagggttac actgaagatg   2820

cacaatccct aaaataaaga tcaccacttc cccaaagaag cagccctcgg gtccatgtgt   2880

tgttcagaca tgtgaagaga agcaagacag agggtctcag atggacgagg gctctccaag   2940

ggaatgcctg gggattcacc cagtggtccc cagaggtgct ccatggaggc aacaagtcat   3000

tccatgaagc cccagaggta gaagggacct caagcaccac gccctccagg gcagccgtgc   3060

agacgacctt ggttcacttt tcaggggtcg tcccaactct gtatctccag ccactccaac   3120

tgtggaggct gtaaatccag attttcactg ttccagtctc ctttgcagct taggatggct   3180

atgtgatcag gtgtggccaa tgaaattgaa gaggaagtct acctgggctt ctgggaaagc   3240

ttttccaata aaagacacag gcatggctaa cacctccctg ggcctcttct tcctaccttg   3300

attgagggtg tgatgcctgg agccacagca gccactttgc taccatgaca aaaaggccaa   3360

gagaatcaca gagtcattga ccctatcatt atttcaccaa gccaatacca gccgccatcc   3420

ttctccagaa ttcttgtaaa taaaataaat ccctctttgt ttaaa                   3465


<210>  723
<211>  4577
<212>  DNA
<213>  Human

<400>  723
agctgtcgcg ggcagccgcc tcacagcgat ggcggccgag cagggccggt ggcggcggcg     60

gctgcggcta cggccggaga cggcagtgtt ggcggtagtg gtgggtggca ggggcctgtg    120

accgggagct gcccccggac ccgggcacca tgagccaagg cccccccaca ggggagagca    180

gcgagcccga agcaaaagtc ctccacacta agcggcttta ccgggctgtg gtggaggctg    240

tgcatcgact tgacctcatc ctttgcaaca aaactgctta tcaagaagta ttcaaaccag    300

aaaacattag cctgaggaac aagctgcgtg agctctgcgt caagcttatg ttcctgcacc    360

cagtggacta tgggagaaag gctgaggagc tgctgtggag aaaggtatac tatgaagtta    420

tccagcttat caagactaac aaaaagcaca tccacagccg gagcactttg gaatgtgcct    480

acaggacgca cctggttgct ggtattggct tctaccagca tctccttctc tatatccagt    540

cccactacca gctggaactg cagtgctgca tcgactggac ccatgtcact gaccccctca    600

taggatgcaa gaagccagtg tctgcctcag ggaaggagat ggattgggca cagatggcat    660

gtcaccgatg tctggtgtat ctgggggatt tgtcccgata tcagaatgaa ttagctggcg    720

tagataccga gctgctagcc gagagatttt actaccaagc cctgtcagta gctcctcaga    780

ttggaatgcc cttcaatcag ctgggcaccc tggcaggcag caagtactat aatgtggaag    840

ccatgtattg ctacctgcgc tgcatccagt cagaagtgtc ctttgaggga gcctatggga    900

acctcaagcg gctgtatgac aaggcagcca aaatgtacca ccaactgaag aagtgtgaga    960

ctcggaaact gtctcctggc aaaaagcgat gtaaagacat taaaaggttg ctagtgaact   1020

ttatgtatct gcaaagcctc ctacagccca aaagcagctc cgtggactca gagctgacct   1080

cactttgcca gtcagtcctg gaggacttca acctctgcct cttctacctg ccctcctcac   1140

ccaacctcag cctggccagt gaggatgagg aggagtatga gagtggatat gctttcctcc   1200

cggaccttct catctttcaa atggtcatca tctgccttat gtgtgtgcac agcttggaga   1260

gagcaggatc caagcagtac agtgcagcca ttgccttcac cctggccctc ttttcccacc   1320

tcgtcaatca tgtcaacata cggctgcagg ctgagctgga agagggcgag aatcccgtcc   1380

cggcattcca gagtgatggc acagatgaac cagagtccaa ggaacctgtg gagaaagagg   1440

aggagccaga tcctgagcct cctcctgtaa caccccaagt gggtgagggc agaaagagcc   1500

gtaagttctc tcgcctctcc tgtctccgcc gtcgccgcca cccacccaaa gttggtgatg   1560

acagtgacct gagtgaaggc tttgaatcgg actcaagcca tgactcagcc cgggccagtg   1620

agggctcaga cagtggctct gacaagagtc ttgaaggtgg gggaacggcc tttgatgctg   1680

aaacagactc ggaaatgaat agccaggagt cccgatcaga cttggaagat atggaggaag   1740

aggaggggac acggtcacca accctggagc cccctcgggg cagatcagag gctcccgatt   1800

ccctcaatgg cccactgggc cccagtgagg ctagcattgc cagcaatcta caagccatgt   1860

ccacccagat gttccagact aagcgctgct tccgactggc ccccaccttt agcaacctgc   1920

tcctccagcc caccaccaac cctcatacct cggccagcca caggccttgc gtcaatgggg   1980

atgtagacaa gccttcagag ccagcctctg aggagggctc tgagtcggag gggagtgagt   2040

ccagtggacg ctcctgtcgg aatgagcgca gcatccagga gaagcttcag gtcctgatgg   2100

ccgaaggtct gcttcctgct gtgaaagtct tcctggactg gcttcggacc aaccccgacc   2160

tcatcatcgt gtgtgcgcag agctctcaaa gtctgtggaa ccgcctgtct gtgttgctga   2220

atctgttgcc tgctgctggt gaactccagg agtctggcct ggccttgtgt cctgaggtcc   2280

aagatcttct tgaaggttgt gaactgcctg acctcccctc tagccttctg ctcccagagg   2340

acatggctct tcgtaacctg cccccgctcc gagctgccca cagacgcttt aactttgaca   2400

cggatcggcc cctgctcagc accttagagg agtcagtggt gcgcatctgc tgcatccgca   2460

gctttggtca tttcatcgcc cgcctgcaag gcagcatcct gcagttcaac ccagaggttg   2520

gcatcttcgt cagcattgcc cagtctgagc aggagagcct gctgcagcag gcccaggcac   2580

agttccgaat ggcacaggag gaagctcgtc ggaacaggct catgagagac atggctcagc   2640

tacgacttca gctcgaagtg tctcagctgg agggcagcct gcagcagccc aaggcccagt   2700

cagccatgtc tccctacctc gtccctgaca cccaggccct ctgccaccat ctccctgtca   2760

tccgccaact ggccaccagt ggccgcttca ttgtcatcat cccaaggaca gtgatcgatg   2820

gcctggattt gctgaagaag gaacacccag gggcccggga tgggattcgg tacctggagg   2880

cagagtttaa aaaaggaaac aggtacattc gctgccagaa agaggtggga aagagctttg   2940

agcggcataa gctgaagagg caggatgcag atgcctggac tctctataag atcctagaca   3000

gctgcaaaca gctgactctg gcccaggggg caggtgagga ggatccgagt ggcatggtga   3060

ccatcatcac aggccttcca ctggacaacc ccagcgtgct ttcaggcccc atgcaggcag   3120

ccctgcaggc cgctgcccac gccagtgtgg acatcaagaa tgttctggac ttctacaagc   3180

agtggaagga aattggttga tactgacccc caggccctgc agtggggctg actccagatc   3240

tctcctgccc tccctggcag ccaggaccag cacctgtagt caccccacca cacgcagact   3300

catgcacgca cacaggaggg aggcctagct gctcagaggc tgcagggagg gcccaggagc   3360

cggctgggag ggtggggtcc ctttgttgcc aagacgttag gaaagcgagg aaagtgcttg   3420

gattaggaga gtcttgtggg cccctggcca gccttcctgc ctcagctccc ctgctgtctc   3480

caggggcagg tggtaggcat gggtacctgc atttcactgg aatgggttct tggatctctg   3540

aggggaagga acagcaaaag aggcccttct tcctcaccca agatgcaggg tggttggggc   3600

caggagtttg gaccctctag gtcttggggg aagagctggg taatacctgg tgtctgagtg   3660

attctctgca gacccttccc ctcctcaagg atcacccatc ctcctttcag ccccctttat   3720

ggggaccagg cagctctgga gccagccaca ggggctgtta gagaagcaag gcctggagtg   3780

gcctgcaccg agtagcaggg tcagggttcg tgtgctcctc ctcctgctgc aggggctgca   3840

catcccattg ccccacttct gctttgtgtc tccctctgtc tagcttccag ggcagggagc   3900

aggccccacc tagggctgca ggcagtctgg cctgtgccag cacggtctcc tgtgcccacc   3960

agccccacag gtgctgtgct ttgtgctctt ggctgctgtg ctgggacaga atgggatgcc   4020

aggaagagaa gaaagggggt gcagtctgag gccaccaccc cccttcctat ctaagggagg   4080

gctgaagaca aggggccggc attcagtggg cagcagaaag gagaggctcc ttgaagctgc   4140

tcagtcagag gcccccgtcc ctccttttgc cttccgcagg actgaagacc tgaaggggct   4200

ggcttttgga gtgttgaggt gaatatctgg gagcagagat catgaatagc tcagggcagt   4260

gaatggcgca ccaagagcag ggctgtgtgt gggaggctgc agccaggatt gcctcagctc   4320

ctccccctca ggctgggagg atagcacagg ctaggggctc ggggtggagg gtctcagctc   4380

tgctgccccc accccagtac tagcctagct tcccaagctg tggcttagag gatagttggc   4440

ttcctgcctc tctcctctaa aatagcaagt ctgggaaatc ctggggtgag tggagtcacc   4500

ccactcccag ttgctggcag agactgagac taaagcatca cttaataaac cccccaagcc   4560

caaaaaaaaa aaaaaaa                                                  4577


<210>  724
<211>  5238
<212>  DNA
<213>  Human

<400>  724
ggcgctgcga agtggaggcg ctgcgagcgg agccgcgcgg agggcgcgac cggctggtcc     60

gggcagcgtg ggtttgccgc cttcggggct ccagtccgcg cgccagggct cgagcagtac    120

cgcgggcccc tcaggtgggc ctcggctcgg gacgccggga gtcgggaccg ccagtcgggg    180

cgccgggacc atggcgctgc gcgcccgggc gctgtacgac ttcaggtcgg agaacccagg    240

agagatctcg ctgcgagagc acgaggtgct gagcctgtgc agcgagcagg acatcgaggg    300

ctggctcgag ggggtcaaca gccgcggcga ccgcggcctc ttcccggcct cctatgtgca    360

ggtgatccgc gcccccgagc ctggcccggc gggagacggc ggcccgggcg ccccggcccg    420

ctacgccaat gtgccccccg ggggcttcga gcccctgcct gtcgcgcccc ccgcctcctt    480

caagccgccg cctgacgcct tccaggcgct gctgcagcca cagcaggcgc cgcctccgag    540

caccttccag ccgcccggcg cgggcttccc gtacggcggg ggcgccctgc agccgtcgcc    600

tcagcagctc tacggcggct accaggccag ccaaggcagc gatgatgact gggacgacga    660

gtgggacgac agctccacgg tggcggacga gccgggcgct ctgggcagcg gagcataccc    720

ggacctcgac ggctcgtctt cggcgggtgt gggcgcagcc ggccgctacc gcctgtccac    780

gcgctccgac ctgtccctgg gttcccgcgg cggctcggtc cccccgcagc accacccgtc    840

ggggcccaag agctcggcca ccgtgagccg caacctcaat cgcttctcca ccttcgtcaa    900

gtccggcggg gaggccttcg tgctggggga ggcgtcaggc ttcgtgaagg acggggacaa    960

gctgtgcgtg gtgctggggc cctatggccc cgagtggcag gagaacccct acccgttcca   1020

gtgcaccatc gacgacccca ccaagcagac caagttcaag ggcatgaaga gctacatctc   1080

ctacaagctg gtgcccacgc acacgcaggt gccggtgcat cggcgctaca agcacttcga   1140

ctggctgtac gcgcgcctgg cggagaagtt cccggtcatc tccgtgcccc acctgcccga   1200

gaagcaggcc accggccgct tcgaggagga cttcatctct aagcgcagga agggcctgat   1260

ctggtggatg aaccacatgg ccagccaccc agtgctggcg cagtgcgacg tcttccagca   1320

cttcctgacg tgccccagca gcaccgacga gaaagcctgg aagcagggca agaggaaggc   1380

cgagaaggac gagatggtgg gcgccaactt cttcctgacc cttagcacgc cccccgccgc   1440

tgcccttgac ctgcaggagg tggagagcaa gatcgacggc ttcaagtgct tcaccaagaa   1500

gatggacgac agcgcgctgc agctcaacca cacggccaac gagttcgcgc gcaagcaggt   1560

gaccggcttc aaaaaggagt atcagaaggt gggccagtcc ttccgcggcc tcagccaggc   1620

ctttgagctg gaccagcagg ccttctcggt gggcctgaac caggctatcg ccttcaccgg   1680

agatgcctat gacgccattg gcgagctctt cgcggagcag cccaggcagg acctggatcc   1740

cgtcatggac ctattagcgc tgtatcaggg gcatctggct aacttcccgg acatcatcca   1800

cgttcagaaa ggagctctta ccaaagtcaa ggagagtagg cgacacgtgg aggaagggaa   1860

gatggaggtg cagaaggctg acggcattca ggatcgctgt aacactattt cttttgccac   1920

tttggctgaa attcaccact tccatcaaat tcgagtgaga gactttaaat cacagatgca   1980

gcatttctta caacaacaaa taatattttt ccaaaaagtt acccagaagt tggaagaagc   2040

tcttcacaaa tatgatagtg tttaatgact ggacgttgga ttatggactt tttcagttca   2100

aggataattt ctacagcaga ataaaaactg ctgtcaaaga gctattgcca gctatcagtg   2160

gtggtacaag gacggttttg tgttcatctg aaacccagct gaatttataa ttatgtagga   2220

aataaacagt taatatggtt atataataga aacagtacca cacattgtaa ctaaattata   2280

ctatgtatgc ctacactacc attgtaactt ttggaataat gattatacta tttgccttat   2340

tgctttttga agtatgggta ttttagtgca tactttgtag acctcaaaac ccatgaaggg   2400

tctcaaagaa gctggctgga tacaagcctg ctgtggatgc ctttttactc tcatagattg   2460

ggattaccta aattcaacct attctctgtt tacaaactcc aactagagca gctatgcgac   2520

cttgtgcctt tagactcttg gtttttcatt tctccccgtc ccttccccac ctttttaaag   2580

taagccacag cttttctgat tgaaagagtg aaaggccagt gcatataatg acaaactgat   2640

gataacctta tattggcagt agggggtggg gggggcggtg gggtgggacg atcagctgtc   2700

atcaatttgc acagcaagta ttatctcctg ataagatgct ggtgaatgca ggggagtgag   2760

attcattgct catctttgga tatgaagtct gttagggaag aaacagtgcc actattccct   2820

tagatgcaac agtagcatag cctcttcacc caggcgtccc aaaagcttgg cgtgaagatt   2880

tcagcaaaca tgtcttacaa catgaggagg aggagtctaa atcagtcagg ggataaaagt   2940

atcgaatcat tgacaacaca cacttggctt tagttcttag gagggttttg tttttgtttt   3000

tgtttttagg ttgaagattt tcttttaata ttcagttttt tgaaaaaaaa tggatctaca   3060

ctgttaactg attgagactc cactgtgatt cacttgttta cttaaaaact tttcagggat   3120

gtctgtaaat ttcagtgtta atatgtcatg aaaagtggtg tggattgatc taaggaggga   3180

ccagaaataa tttttgctat tccaaatact gaaggaaaaa gataattgat ttatactatg   3240

ttttaaaaaa aaaaaaggta ttgatgagcc cccccccccc aggacattta accttaaaat   3300

ttattttaaa tgtattcttt tattattata agggaaatac agatggctga taaataccaa   3360

aaagattcaa aagcagctta atttaaaaag cacaaagaga ttctggctta cagtgcccca   3420

atctcaatgt ttttatagtt gctgagctaa ctaatgtgat tattgagttt acagatttaa   3480

aaattgtcac tgttagagta tctactgttt ttatgaagtc aaacttatgc tgcctcagaa   3540

atccctgggt actgaaatgg taacatggaa gtgaagaggt cactttgaaa tattggtgag   3600

tcacaaagat taaagaaaag gatcagtttg cagatactca gaaaaggtta ttgaaataat   3660

tactgaacag cacattttct ctctaaaaag tagtttcata tgggttgtat ttttaagatc   3720

agattatcat tttgatattt ggtcaaaatt ttgtacctta ggttacttag agccagattt   3780

aacatcatga acattatgtg gctttgtctt tactacagat atgtggaact gtaaccaaat   3840

atgttgtctc taaaacttgt tgattgcaaa atacagttct ataaacaaaa cccatatgta   3900

tatataaatg ttaattttgc ggaagtctgg aaattataac tatagcattt aagtttgagt   3960

ctgtattgga caaataagca ccatgctttt caaatgattt aaaaattact tttatttgcc   4020

tctttatttt gatggtggtt ggattttttt ttttttaata gtaaaatcac taaacttgtg   4080

caatggtagc atggaaatta tctgaggtat attgtatgat tgtactttag ccagggtgga   4140

catagcttaa attataaaaa ctaaagatga aagtacaagg aagtataagt tatacttatg   4200

taagtataaa ttcatgctgc ctacttctaa gagaaatttc attcttcata accacataac   4260

attataatgc cactgattca tacgggattt acattaattc tatgggggag gacactagaa   4320

ttattagtgt tcattttcat ctaagatctt tattctctaa cgttcttggt cctattgaaa   4380

cattgcagta tgcaaaacta ctgcaatgtt aaacccaaga gaaaagccat tatcatgtgt   4440

atgctggtca tcatgatcag tgtggtacaa tttttaaaaa taaactatca tgcccttcat   4500

gccattattt gtctttattt ctatgattta taatcctgat atgtgatgtg tttgtaacac   4560

agggtgtgca cttgagcctg gttttactgt ttttattaga cagagttgtt tatatgctgt   4620

aactgtaacg cagcgagact ggttctacag ccatgtgtcg taatcttgtt ccccgtccaa   4680

gctgttgtat ctgaaggtac ccagtttgca cccaggatga gggaacgcat tcaaaagtga   4740

aatgtaaagc cagtgcacga atattatagt aattgagatt ttcccaggct tcactgatac   4800

agttgttttg catttattca caataataca gcagattctt aaatgccgat ttttaattgt   4860

cttaaatttt gctgctgttc tcataattaa ggacttgaaa aatgttttag tctgtcaagt   4920

atgtaaagtt tgtgtaaaaa cttttaaatg tcattcttaa gttcattgcc atagccattt   4980

tccatttatg tcttcatttt ccaaaaatca aatgccatgt ctgatacctt taagtccata   5040

agcattcaat tttctcattt ccaccttcat ctttggttaa cagaataagt aaaacagggt   5100

attatttatt tgtagtctag aaatgttgaa tattgtttta tttccttcaa aatgttatga   5160

ttagtgcaga tcagccatgt ttatcttttt aaaaaataaa caggttgctt tatttcttaa   5220

aaaaaaaaaa aaaaaaaa                                                 5238


<210>  725
<211>  3249
<212>  DNA
<213>  Human

<400>  725
cgcggctgca tggacgcggg tccggcgcgc gggaggcgat gacggccccg ccatggcccg     60

ggcgggcagc tgcggcggcg ccgcggcggg cgcagggcgg ccggagccct gggagctgtc    120

cctggaggag gtgctgaagg cctacgagca gccgctcaac gaggagcagg cgtgggccgt    180

gtgcttccag ggctgccgcg ggctgcgggg ctcgccgggc cggcgcctgc gggataccgg    240

ggacctcctg ctgcgcgggg acggctcggt cggggcgcgg gagcccgagg ccgcggaacc    300

tgcaaccatg gtcgtgccac tagccagctc ggaagcccag accgtgcagt ccctcggctt    360

cgccatctac cgcgcgctgg actgggggct ggacgagagc gaggagcgcg aactcagccc    420

tcagctggag cggctcatcg acctcatggc caacaacgac agcgaggaca gcggctgcgg    480

tgccgccgat gagggctacg ggggtcccga ggaggaggag gaggccgagg gcgtcccccg    540

cagcgtgcgc acctttgccc aggccatgcg gctgtgcgcg gcgcggctga ccgacccccg    600

gggcgcacag gcgcattacc aggccgtgtg ccgcgcgctc ttcgtggaga cgctggagct    660

gcgggccttc ctggccaggg tccgggaggc caaggagatg ctgcagaagc ttcgggagga    720

cgagccgcat ctggagacgc ctcgggcaga gctggacagc ctgggtcaca cagactgggc    780

ccgactgtgg gttcagctca tgcgggagct ccgccgcgga gtgaagctga agaaggtgca    840

agagcaggag ttcaaccccc tccccaccga gttccagctc acgcccttcg agatgctgat    900

gcaggacatc cgggcccgga actacaagct gcgcaaggtc atggtggatg gggacatccc    960

gccccgggtg aagaaggacg ctcacgagct catcctggac tttatccgct cacggcctcc   1020

actgaagcag gtctctgaga ggcggctgcg cccgttgcca ccaaagcaaa ggtccctgca   1080

tgagaagatc ctggaggaga tcaagcagga gcggaggctg cgcccggtgc ggggcgaggg   1140

ctgggctgcc cgcgggtttg gctctctgcc ctgcatcctc aacgcctgct ccggagatgc   1200

caagtccacc tcctgcatca acctgtcagt cacagatgct gggggcagcg cccagcgccc   1260

gcggccccgc gtgctgctca aggcgcctac cttggctgaa atggaagaga tgaatacatc   1320

tgaggaagaa gagtctccgt gtggggaggt gacgctgaaa cgggaccgct ccttctcaga   1380

gcatgacctg gcccagctcc gaagtgaggt ggcctctggc ctgcagtcgg ccacccaccc   1440

cccaggaggg acggagccac cacggccccg agctggcagt gcgcatgtgt ggaggcccgg   1500

ctcccgagac cagggtacct gtcccgcgag tgtctctgac cccagccacc ccctactcag   1560

caaccggggc tcctcggggg acagacccga ggcctccatg acccccgatg ccaaacacct   1620

gtggctggag ttcagccacc ccgtggagag cctggcgctg actgtggaag aggtgatgga   1680

cgtgcgccgt gtgctggtga aggccgagat ggaaaagttt ttgcagaaca aggagctctt   1740

cagcagtctg aagaagggga agatttgctg ctgctgccgg gccaagttcc cgctgttctc   1800

gtggccgccc agctgtctct tctgcaagag agccgtctgc acttcctgta gcataaagat   1860

gaagatgcct tctaagaaat ttggacacat ccctgtctac acactgggct ttgagagtcc   1920

tcagagggta tcagctgcca aaaccgcgcc aatccagaga agagacatct ttcagtctct   1980

gcaagggcca cagtggcaga gcgtggagga ggcgttcccc cacatctact cccacggctg   2040

tgtcctgaag gatgtctgca gtgagtgcac cagctttgtg gcagacgtgg tgcgttccag   2100

ccgcaagagc gtggacgtcc tcaacactac gccacgacgc agtcgccaga cccaatccct   2160

ctacatccct aacaccagga ctcttgactt caagtgacag ccccaggtgg ccaggcctcc   2220

aggaggcacc aggcaggccc tgtatcaggc taggacgctc tgagctgtgc atgtacatat   2280

atacatatat agatacattt ataatatata cacacagtct atatatttat atacactgtt   2340

tcctggcccc agagctcatt tgggttcagg cgcacttcaa aaccctccct gggggaggct   2400

gtttcttctc aggattcctt gccagggagg aaggggaggg aacagggtgg gttttctcac   2460

tgaagagaga aagcagaagg ttctagatcc tggcacagac tgcatcccat gttcccatgc   2520

tcttctccgt ccccaggaat gcgaacggca gtttcccttc cccagtggac gtctaggtgg   2580

ggacagggta tcttggctcc cagctggacc agagtgccct gcttgcctct gctctccctt   2640

tgtggggact caggcagcag aggcatctgg gaagtctctg agtaggcagg gtcctcctgg   2700

gaggcacccc cacctgtttg aaaggtctgg ccaggcgtgg tggttcaggc ctgtaattcc   2760

agcactttgg gaggccgagg agggaggatc acctgaggtc aggagtttga gaccagcctg   2820

gccaacatga tgaaatgttg tctctactga aaatgcaaaa attagccagg tatagtggca   2880

ggaacctgta atcccagcta caggggaggc tgaggcagga gaatcgcttg aacccgggag   2940

gtgtaggttg cagtgagccg agattgcacc actgcactcc agcctgggcg acagagcgag   3000

actctgtctc gaaaaaaaaa aaggtccgtg ccaagctgct ccctgccctt gccctttccc   3060

tttccctggg gtccaaacca catgtgtcct gcctctcctg gccctaccac attctggtgc   3120

tgtcctcact cgcccctggc ccagaggctc ctgaagatgc tgggcggtcc tggcacaggg   3180

aggagcagct ctgtaaatct gtgcacatgg ccactcttgg cctaataaag gaggtctcac   3240

agtcaaaaa                                                           3249


<210>  726
<211>  2894
<212>  DNA
<213>  Human

<400>  726
gagaagctcc gcgggcccgg ctgggcgagt gtctggccct ttaagggccg cccccgagga     60

ggtgccaggc ccgggtggcg ccgtccgtcc ttcctggtcc tgcgggtcca ggactgtccg    120

cggggttgag ggaaggggcc gtgcccggtg ccagcccagg tgctcgcggc ctggctccat    180

ggccctggtc acagtgagcc gttcgccccc gggcagcggc gcctccacgc ccgtggggcc    240

ctgggaccag gcggtccagc gaaggagtcg actccagcga aggcagagct ttgcggtgct    300

ccgtggggct gtcctgggac tgcaggatgg aggggacaat gatgatgcag cagaggccag    360

ttctgagcca acagagaagg ccccgagtga ggaggagctc cacggggacc agacagactt    420

cgggcaagga tcccagagtc cccagaagca ggaggagcag aggcagcacc tgcacctcat    480

ggtacagctg ctgaggccgc aggatgacat ccgcctggca gcccagctgg aggcaccccg    540

gcctccccgg ctccgctacc tgctggtagt ttctacacga gaaggagaag gtctgagcca    600

ggatgagacg gtcctcctgg gcgtggattt ccctgacagc agctccccca gctgcaccct    660

gggcctggtc ttgcccctct ggagtgacac ccaggtgtac ttagatggag acgggggctt    720

cagcgtgacg tctggtgggc aaagccggat cttcaagccc atctccatcc agaccatgtg    780

ggccacactc caggtattgc accaagcatg tgaggcagct ctaggcagcg gccttgtacc    840

gggtggcagt gccctcacct gggccagcca ctaccaggag agactgaact ccgaacagag    900

ctgcctcaat gagtggacgg ctatggccga cctggagtct ctgcggcctc ccagcgccga    960

gcctggcggg tcctcagaac aggagcagat ggagcaggcg atccgtgctg agctgtggaa   1020

agtgttggat gtcagtgacc tggagagtgt cacttccaaa gagatccgcc aggctctgga   1080

gctgcgcctg gggctccccc tccagcagta ccgtgacttc atcgacaacc agatgctgct   1140

gctggtggca cagcgggacc gagcctcccg catcttcccc cacctctacc tgggctcaga   1200

gtggaacgca gcaaacctgg aggagctgca gaggaacagg gtcacccaca tcttgaacat   1260

ggcccgggag attgacaact tctaccctga gcgcttcacc taccacaatg tgcgcctctg   1320

ggatgaggag tcggcccagc tgctgccgca ctggaaggag acgcaccgct tcattgaggc   1380

tgcaagagca cagggcaccc acgtgctggt ccactgcaag atgggcgtca gccgctcagc   1440

ggccacagtg ctggcctatg ccatgaagca gtacgaatgc agcctggagc aggccctgcg   1500

ccacgtgcag gagctccggc ccatcgcccg ccccaaccct ggcttcctgc gccagctgca   1560

gatctaccag ggcatcctga cggccagccg ccagagccat gtctgggagc agaaagtggg   1620

tggggtctcc ccagaggagc acccagcccc tgaagtctct acaccattcc cacctcttcc   1680

gccagaacct gagggtggtg gggaggagaa ggttgtaggc atggaagaga gccaggcagc   1740

cccgaaagaa gagcctgggc cacggccacg tataaacctc cgaggggtca tgaggtccat   1800

cagtcttctg gagccctcct tggagctgga gagcacctca gagaccagtg acatgccaga   1860

ggtcttctct tcccacgagt cttcacatga agagcctctg cagcccttcc cacagcttgc   1920

aaggaccaag ggaggccagc aggtggacag ggggcctcag cctgccctga agtcccgcca   1980

gtcagtggtt accctccagg gcagtgccgt ggtggccaac cggacccagg ccttccagga   2040

gcaggagcag gggcaggggc aggggcaggg agagccctgc atttcctcta cgcccaggtt   2100

ccggaaggtg gtgagacagg ccagcgtgca tgacagtgga gaggagggcg aggcctgagc   2160

cctcacacat gcccacgctc ccctgacact gaagaggatc cacaactcct tggagaaaca   2220

ccctcacgtc tgttgccgca cacattcctc tcagctccgc cccatacccg tcactacagc   2280

ctcacctccc acccctgtca ctacggcctc acctcccacc cctgtcacta cagcctcacc   2340

tcctacagcc ttaagtccca ggcccatgtc tgcctgtcca agggctcaag actttctaac   2400

tgggatgtgg tagagggact gaaggtacct ttgggggcaa cagcacccta gtttcattct   2460

caactctagc cctgcacact cacctgtggc acggaatgaa aacagagctt cccgtgcaaa   2520

aagggtcacg cctcccaccc ccgccccctc cctgcacctc ctgtcctctc ccagttcatt   2580

cctggaacca gccaggccag gcaaccagtg gcccccaaag gcaggcagga tcctcaggcc   2640

ccagccgcgg gaggctggaa gggctggcag atcgcttccc tcatccacct ccaccggtcc   2700

aggtctttgc tgctgtcccc agacctcctg tgacaccacg ccagatcaca gggcaccagg   2760

ccagagatag tcttcttttt gtcctttctg gcctctggct agtcagtttt tcatagcctt   2820

acagtatctg gctttgtact gagaaataaa acacattttc atatttggtt attttcaaaa   2880

aaaaaaaaaa aaaa                                                     2894


<210>  727
<211>  3949
<212>  DNA
<213>  Human

<400>  727
ggtagtctgc ctgccgcagt ccgagcgccg cgctggggag agcgggtgtt tgaaggctcc     60

gcggaccggc actaggagcc gggggcgggt ccgtgaccct ccggctgctc ggagtgaaca    120

ggcggccagg aaagaagcgg gcctgaacac catgatccct ttggagaagc caggcagcgg    180

cggctcctcc ccaggcgcca cctcaggctc gggccgggca ggccggggtc tgagcgggcc    240

gtgccggccg ccgccgccgc cccaggcccg cgggctgctg acagagatac gcgccgtggt    300

gcgcaccgag cccttccagg acggctacag cctgtgcccg ggccgggagc tgggcagggg    360

gaaatttgca gtggtgagaa aatgtataaa gaaagattct gggaaagaat ttgctgcaaa    420

gttcatgaga aaaagaagaa aaggccaaga ttgtcggatg gaaataattc atgagattgc    480

tgtacttgaa ctagcacaag acaatccttg ggtcattaat ttacatgaag tttatgagac    540

tgcatcagaa atgatcttag ttctggaata tgctgctggg ggtgaaatct ttgaccagtg    600

tgttgcagac agagaagaag cctttaaaga aaaagatgtt caaagactta tgcgacagat    660

tttagaaggt gttcactttt tacacactcg tgatgtagtt catcttgatt tgaagcctca    720

gaatattctg ttgacaagtg aatctccatt gggtgacatt aagattgttg attttggcct    780

ttcaagaata ttgaagaaca gtgaagagct ccgagaaatt atgggtaccc ctgaatatgt    840

ggctcctgaa attcttagtt atgatcctat aagcatggca acagatatgt ggagcattgg    900

agtgttaaca tatgtcatgc ttacaggaat atcacctttc ttaggcaatg ataaacaaga    960

aacattctta aacatctcac agatgaattt aagttattct gaggaagaat ttgatgtttt   1020

gtctgagtcg gctgttgatt tcatcaggac acttttagtt aagaaacctg aagatcgagc   1080

cactgctgaa gaatgtctaa agcacccctg gttgacacag agcagtattc aagagccttc   1140

tttcaggatg gaaaaggcac tagaagaagc aaatgccctc caagaaggtc attctgtgcc   1200

tgaaattaat tcggataccg acaaatcaga aaccaaggaa tccattgtaa ccgaagagtt   1260

aattgtagtt acttcatata ctctaggaca atgcagacag tctgaaaaag agaaaatgga   1320

gcaaaaggcc atttccaaac gatttaaatt tgaggaacct ttgctacaag aaattccagg   1380

agaatttatc tactgagcaa tatttccctt tagaacttca agatttctac attgaaaatg   1440

ttaatattat ttatggacct ctggccaaat ggtacatgta ctggaagtgg ataaccagta   1500

tcacttacac aaacaaaaat aactttgtca aatttgtgga gttaggtgga agccagattt   1560

taaaagttgc caaccaggag atttaacagg tacagttacc cgtttcaatg ttatttttaa   1620

gaagggagat gttggcacct ttgaattcta catcctgttt ctccagaatg agaatttgtg   1680

tacaaagata tttgtattca ctttctttaa aaaatccaag taaaagtgcc aaaactacac   1740

ttctgtaaat ctcttgcatt attcatatgt gtatctatat ctgcataatg tttgttaatg   1800

tctactaaaa ttgctacttt ttcactttgg atttgttttt ggcaaaattt tagtctaaac   1860

agacatctaa attttcgaga cttagaataa cattcactaa agtttgataa tgtctttttt   1920

aaatattttc ttactgcttt atagtgactt gatttggttt ctgttgtgtt tttgcctaaa   1980

tactagtaac atatcagtga aaaaccctaa ttttttttct cttcaatgtc actagtaaga   2040

gaggtggtaa tttttcacct ctgaaattat tctgggttta ggtgtcagct cttgagctgc   2100

ttccctcatc acaccacact cacatgcatc tgttctctct cacactctat acccctgcca   2160

cttcctggca cctcccccca tgcttgtcat ttaattttgg ccacttgtag gtatcagtgt   2220

gatctgatca acactctggt taccttggtc agtgaaaaga tgctactata ttgcttttgt   2280

cccaaagtga gtaaaatccc ctagagcaga gagagagaga gagagagaga gtgtcttcat   2340

gccaaccaca gcctgtttct gctgagtttc ttatcagccc tcaagctatg ctaggaaaag   2400

ttataaaatg ccaaaatatt tataaacatt tactttgtcc ataaaaaatt tacattggat   2460

actctgtaag taggaggtac tttgtcccaa aaagatgtat aagaatgtac taatagtttt   2520

atttgattag gattgaacag ttcagttgta tctatgcccc acagtgacca gtaaagtcca   2580

attaaaatat ggaaatgtaa aagtgtatgc cgaatacctt aaagtaacta attatcctta   2640

cacacaaaag gctcagtgca ttaaatattt gcctatcacc tgtgtgctgt gtaccgtggc   2700

catgcctcgc tctgcactat gaacaactca gacctgtccc ttcacggtct gattagggtg   2760

tcacacaaag ctctctccct aacatggttt ctcaactgtc aaaatcatga aaatgacagc   2820

acctaaccac tattttaaag tatgtacagt aaatacccaa atgtgtgtaa atgtcataga   2880

catatacaaa gtcagtaatc tcacccagtc ctgctgtgtg aacctgtcaa agcacctggg   2940

agtgcccttt acaccattag gtgaaattca tcaggcactt cagacaacca ggttgcactg   3000

ttttctcact aaattggctt tatttataca gtttcctgga acctagcatt cctaaacaag   3060

ctccaaaatg cagaagaaga aattgtgcca cagtgataga gtttttaatg aatatccatg   3120

gccacagttt tgagtctcag gtaagtcttg gaagaagtta aacacagtat taggcaaata   3180

tttatctctc tgaaaaaata gggaggaggt gaccaggaaa aaataaccac tattgaatga   3240

cacgtttgta cttgatggat ctgtcatcaa gttttaaaat cagaatcatt tgggcttttt   3300

aaaaaccatt ttatactcgt aataaatata tttaatataa ttgctgtatt tgtgagaaag   3360

atctgttttc ttttagctgg ccacttcagt ttgctgcgta tctttagctg ctgttgtgct   3420

taaatactga gtcatagggt gcttttttaa gaggcccttc agaatatact tgtaaaggtg   3480

tattggcatt ttttggttta taagataaaa acagggcatg aagagccttc atagtattag   3540

gccaaataaa atctattaat aactgccagc tagctctaca cttatctaaa gctgttaatg   3600

ttcctttttt tctatcacca aatttataaa ggactaaaca gtactattga gtttactcgg   3660

tttataaatc cagttttaac tataattcaa caatattttg gtgtggtgaa acgttgttta   3720

tgaaatgtat aaaatgtata agttttaatc aactgggaaa tgatatttga ttgatcttgt   3780

gttttgttgt tttcaaatga aaactaggag gtaattaata cctttctcta gtagtggtat   3840

agaggaagga cagatgctca ttgttgaatc tcttaaattt ttccagctaa cctcagtttg   3900

gaagaaaaat gtattaaagg gttataaaga tcaaaaaaaa aaaaaaaaa               3949


<210>  728
<211>  4562
<212>  DNA
<213>  Human

<400>  728
ggtgctgcgg cccgcgccgc catcttggat tttactctcc atttttctct ggaattattt     60

ttggtgatta attttctggg ggggactggg acgcggggcc cggcggcgcg gccccgcatc    120

gcagcggccg ggcagcgggg cctgggacgc gccccgagga ggagcggggc ggcgcaggcg    180

gagagaacat tgaaagtatt ctctaagcta tttgaagaga gtgactaaat gcacctgggt    240

caggctgtct gtgggtatga agtggttggg agaatccaag aacatggtgg tgaatggcag    300

gagaaatgga ggcaagttgt ctaatgacca tcagcagaat caatcaaaat tacagcacac    360

ggggaaggac accctgaagg ctggcaaaaa tgcagtcgag aggaggtcga acagatgtaa    420

tggtaactcg ggatttgaag gacagagtcg ctatgtacca tcctctggaa tgtccgccaa    480

ggaactctgt gaaaatgatg acctagcaac cagtttggtt cttgatccct atttaggttt    540

tcaaacacac aaaatgaata ctagcgcctt tccttcgagg agctcaaggc atttttcaaa    600

atctgacagt ttttctcaca acaaccctgt gagatttagg cctattaaag gaaggcagga    660

agaactaaag gaagtaattg aacgttttaa gaaagatgaa cacttggaga aagccttcaa    720

atgtttgact tcaggcgaat gggcacggca ctattttctc aacaagaata aaatgcagga    780

gaaattattc aaagaacatg tatttattta tttgcgaatg tttgcaactg acagtggatt    840

tgaaatattg ccatgtaata gatactcatc agaacaaaat ggagccaaaa tagttgcaac    900

aaaagagtgg aaacgaaatg acaaaataga attactggtg ggttgtattg ccgaactttc    960

agaaattgag gagaacatgc tacttagaca tggagaaaac gacttcagtg tcatgtactc   1020

cacaaggaaa aactgtgctc aactctggct gggtcctgct gcgtttataa accatgattg   1080

cagacctaat tgtaagtttg tgtcaactgg tcgagataca gcatgtgtga aggctctaag   1140

agacattgaa cctggagaag aaatttcttg ttattatgga gatgggttct ttggagaaaa   1200

taatgagttc tgcgagtgtt acacttgcga aagacggggc actggtgctt ttaaatccag   1260

agtgggactg cctgcgcctg ctcctgttat caatagcaaa tatggactca gagaaacaga   1320

taaacgttta aataggctta aaaagttagg tgacagcagc aaaaattcag acagtcaatc   1380

tgtcagctct aacactgatg cagataccac tcaggaaaaa aacaatgcaa cttctaaccg   1440

aaaatcttca gttggcgtaa aaaagaatag caagagcaga acgttaacga ggcaatctat   1500

gtcaagaatt ccagcttctt ccaactctac ctcatctaag ctaactcata taaataattc   1560

cagggtacca aagaaactga agaagcctgc aaagccttta ctttcaaaga taaaattgag   1620

aaatcattgc aagcggctgg agcaaaagaa tgcttcaaga aaactcgaaa tgggaaactt   1680

agtactgaaa gagcctaaag tagttctgta taaaaatttg cccattaaaa aagataagga   1740

gccagaggga ccagcccaag ccgcagttgc cagcgggtgc ttgactagac acgcggcgag   1800

agaacacaga cagaatcctg tgagaggtgc tcattcgcag ggggagagct cgccctgcac   1860

ctacataact cggcggtcag tgaggacaag aacaaatctg aaggaggcct ctgacatcaa   1920

gcttgaacca aatacgttga atggctataa aagcagtgtg acggaacctt gccccgacag   1980

tggtgaacag ctgcagccag ctcctgtgct gcaggaggaa gaactggctc atgagactgc   2040

acaaaaaggg gaggcaaagt gtcataagag tgacacaggc atgtccaaaa agaagtcacg   2100

acaaggaaaa cttgtgaaac agtttgcaaa aatagaggaa tctactccag tgcacgattc   2160

tcctggaaaa gacgacgcgg taccagattt gatgggtccc cattctgacc agggtgagca   2220

cagtggcact gtgggcgtgc ctgtgagcta cacagactgt gctccttcac ccgtcggttg   2280

ttcagttgtg acatcagata gcttcaaaac aaaagacagc tttagaactg caaaaagtaa   2340

aaagaagagg cgaatcacaa ggtatgatgc acagttaatc ctagaaaata actctgggat   2400

tcccaaattg actcttcgta ggcgtcatga tagcagcagc aaaacaaatg accaagagaa   2460

tgatggaatg aactcttcca aaataagcat caagttaagc aaagaccatg acaacgataa   2520

caatctctat gtagcaaagc ttaataatgg atttaactca ggatcaggca gtagttctac   2580

aaaattaaaa atccagctaa aacgagatga ggaaaatagg gggtcttata cagaggggct   2640

tcatgaaaat ggggtgtgct gcagtgatcc tctttctctc ttggagtctc gaatggaggt   2700

ggatgactat agtcagtatg aggaagaaag tacagatgat tcctcctctt ctgagggcga   2760

tgaagaggag gatgactatg atgatgactt tgaagacgat tttattcctc ttcctccagc   2820

taagcgcttg aggttaatag ttggaaaaga ctctatagat attgacattt cttcaaggag   2880

aagagaagat cagtctttaa ggcttaatgc ctaagctctt ggtcttaact tgacctggga   2940

taactacttt aaagaaataa aaaattccag tcaattattc ctcaactgaa agtttagtgg   3000

cagcacttct attgtccctt cacttatcag catactattg tagaaagtgt acagcatact   3060

gactcaattc ttaagtctga tttgtgcaaa tttttatcgt actttttaaa tagccttctt   3120

acgtgcaatt ctgagttaga ggtaaagccc tgttgtaaaa taaaggctca agcaaaattg   3180

tacagtgata gcaactttcc acacaggacg ttgaaaacag taatgtggct acacagtttt   3240

tttaactgta agagcatcag ctggctcttt aatatatgac taaacaataa tttaaaacaa   3300

atcatagtag cagcatatta agggtttcta gtatgctaat atcaccagca atgatctttg   3360

gctttttgat ttatttgcta gatgtttccc ccttggagtt ttgtcagttt cacactgttt   3420

gctggcccag gtgtactgtt tgtggccttt gttaatatcg caaaccattg gttgggagtc   3480

agattggttt cttaaaaaaa aaaaaaaaat gacatacgtg acagctcact tttcagttca   3540

ttatatgtac gagggtagca gtgtgtggga tgaggttcga tacagcgtat ttattgcttg   3600

tcatgtaaat taaaaacctt gtatttaact cttttcaatc cttttagata aaattgttct   3660

ttgcaagaat gattggtgct tattttttca aaaatttgct gtgaacaacg tgatgacaac   3720

aagcaacatt tatctaatga actacagcta tcttaatttg gttcttcaag ttttctgttg   3780

cacttgtaaa atgctacaag gaatattaaa aaaatctatt cactttaact tataatagtt   3840

tatgaaataa aaacatgagt cacagctttt gttctgtggt aacctataaa aaaagtttgt   3900

ctttgagatt caatgtaaag aactgaaaac aatgtatatg ttgtaaatat ttgtgtgttg   3960

tgagaaattt ttgtcataag aaattaaaag aacttaccag gaaggttttt aagtttagaa   4020

atattcatgc caataaaata ggaaattata aatatatagt tttaagcact gcatcagtgg   4080

gagttcttgg cttatgttag tttatgttag tttattatga aaacatcaaa gatttttttg   4140

actatattat cagttaaaca aaaaggagtc agatttaatt tgttttttga agcactttga   4200

gaaattaatt ttaattaact taatgagcaa atttttatta ctactttatg ttcaatacca   4260

ggttcttttc atttctctgg attattttgc aaatcattgg acagagaatt tgggaatata   4320

aatctgtaac aggtgtttga caccagtagg tctctttatt tctgggaaat gtgtacctgt   4380

actttctgat atacagtgtt cctaagtaaa aatcaattca ggggatttgt atagtgtcta   4440

taggaaagta gcccatgtct tgaaatatga aaaggaatct gaaggtcatg aaaagtccag   4500

tggagaaaat ctcaatgctt actgttacta ctaattgatt cctactagtt tccaggtttg   4560

gg                                                                  4562


<210>  729
<211>  679
<212>  DNA
<213>  Human

<400>  729
gcatgcgcgc cggcgaccac gcctaaatag ccgcagcctc tgcgcgtcgc cctccacggt     60

taccccggct ctccgcccct ccttctcgcg gcgctcgagg gaccatggcc gatcctcgcg    120

tgagacagat caagatcaag accggcgtgg tgaagcggtt ggtcaaagaa aaagtgatgt    180

atgaaaaaga ggcaaaacaa caagaagaaa agattgaaaa aatgagagct gaagacggtg    240

aaaattatga cattaaaaag caggcagaga tcctacaaga atccaggatg atgatcccag    300

attgccagcg caggttggaa gccgcatatt tggatcttca acggatacta gaaaatgaaa    360

aagacttgga agaagctgag gaatataaag aagcacgttt agtactggat tcagtgaagt    420

tagaagcctg aaacttttct cgtatggggt ggtttttgca ttaaatcctg gggtccattt    480

tacaatccat tatttttgac cactgctatg tgttcaagta gtatgagaat gtgattgttt    540

ttatctggtt acatatatat ttctttgtct aatttaatat gtcaaataaa tgagttcatc    600

taataaaatt gtttatttta tactttacaa aatttttaaa ttaacctttt atcattaaac    660

cacatagact ttatgacag                                                 679


<210>  730
<211>  3715
<212>  DNA
<213>  Human

<400>  730
gacgtcatgt tcgccgggca ggcgaggaaa gaggacgcca tgattggttg gcgctggggc     60

ggcggacggt ggaagggcct ggcgagtcta ggttttacgc ctgtgctgga ctttctcctt    120

ccatgtttcc aggccgtggg gggctacaga gggcgagaag tcggctcagc ggaaacctgg    180

atttggttct aagccgtggg gttgagaagg ggtgaccgga agtgatcgtg ggactgaccg    240

gaagcgaggc ctggagggga aagagagagc gagacctggg agggaggggg cctccagcag    300

aaaggggcgg gggaaaaggt gcaaaagcag cgtgggagcg ccgggctggc ttcctgcggc    360

tgctgctggt ctgactggga agcagcaagc caccactacg aactctcaag aggagtggga    420

gtgcgggagt ccagagctgc ctctgggaag tctgcagtag ttgagcaaag gggtcctcac    480

gttcctgaga gctgggcagg ggggattttg gaacctgggg cagccaagaa cgagcagcca    540

agggtacggg agattagttg tgcacagagc agtgctggtc gggcttgggg gtggctggtg    600

ggcactgcgt gggaaacctt ggtttgtagt tttcttggtt tgcgttactc ctgttgggta    660

gaattaccct ccgcgccttt gtacaagaca cggtgtctcc tggggcaagg aaggagccag    720

gatggcctgg gctctgaagc tgcctctggc cgacgaagtg attgaatccg ggttggtgca    780

ggactttgat gctagcctgt ccgggatcgg ccaggaactg ggtgctggtg cctatagcat    840

gagtgatgtc cttgcattgc ccatttttaa gcaagaagag tcgagtttgc ctcctgataa    900

tgagaataaa atcctgcctt ttcaatatgt gctttgtgct gctacctctc cagcagtgaa    960

actccatgat gaaaccctaa cgtatctcaa tcaaggacag tcttatgaaa ttcgaatgct   1020

agacaatagg aaacttggag aacttccaga aattaatggc aaattggtga agagtatatt   1080

ccgtgtggtg ttccatgaca gaaggcttca gtacactgag catcagcagc tagagggctg   1140

gaggtggaac cgacctggag acagaattct tgacatagat atcccgatgt ctgtgggtat   1200

aatcgatcct agggctaatc caactcaact aaatacagtg gagttcctgt gggaccctgc   1260

aaagaggaca tctgtgttta ttcaggtgca ctgtattagc acagagttca ctatgaggaa   1320

acatggtgga gaaaaggggg tgccattccg agtacaaata gataccttca aggagaatga   1380

aaacggggaa tatactgagc acttacactc ggccagctgc cagatcaaag ttttcaagcc   1440

caaaggtgca gacagaaagc aaaaaacgga tagggaaaaa atggagaaac gaacacctca   1500

tgaaaaggag aaatatcagc cttcctatga gacaaccata ctcacagagt gttctccatg   1560

gcccgagatc acgtatgtca ataactcccc atcacctggc ttcaacagtt cccatagcag   1620

tttttctctt ggggaaggaa atggttcacc aaaccaccag ccagagccac cccctccagt   1680

cacagataac ctcttaccaa caaccacacc tcaggaagct cagcagtggt tgcatcgaaa   1740

tcgtttttct acattcacaa ggcttttcac aaacttctca ggggcagatt tattgaaatt   1800

aactagagat gatgtgatcc aaatctgtgg ccctgcagat ggaatcagac tttttaatgc   1860

attaaaaggc cggatggtgc gtccaaggtt aaccatttat gtttgtcagg aatcactgca   1920

gttgagggag cagcaacaac agcagcagca acagcagcag aagcatgagg atggagactc   1980

aaatggtact ttcttcgttt accatgctat ctatctagaa gaactaacag ctgttgaatt   2040

gacagaaaaa attgctcagc ttttcagcat ttccccttgc cagatcagcc agatttacaa   2100

gcaggggcca acaggaattc atgtgctcat cagtgatgag atgatacaga actttcagga   2160

agaagcatgt tttattctgg acacaatgaa agcagaaacc aatgatagct atcatatcat   2220

actgaagtag gagtgcggcg tttcgtgccc agtggctgct ccttccttca cctctgaaaa   2280

cggccctctt gaagggggat atgaatggag atttgaaggt ctgcaagaac ctgactcgtc   2340

tgactgtgtg tggaggagtc caggccatgg aggcagaatc ctggccctct gtgttggccc   2400

aagctcttgt ggtacacaca gattactgcc caatatgcag ttctgcagct gttttagtta   2460

aatttctgga ccttgttgtt gttaaatatc agtagaaact ctacataatt tagagtgtat   2520

gtagggcata atgatgatgg gaattgtgtg atgtttaaca ggaagatctt aaattttgtg   2580

atatggagcc ctgtaatttt tttcttatat aaaaatgggt atctatattc ataagactag   2640

gtcttcaatc tctttgtact ggtctcaaat gtactggtat ctctgctttt tgccacagtt   2700

tgtccctgaa aactttatca gtgaggagaa atacagaatt ttccttttgg ttcccctgta   2760

ataccacaac taatagtatt ttcagctaac atttattgac caggcagtgt gataaatttt   2820

ttgaatgacc atcttgttta accccctaat cacactatct gaagtaggtg ctatagtgac   2880

ccccaaccga agatgaggaa atggagacac acagtggcta agtagcttgc taggtgccag   2940

gagctggcag gcagtgatgc tgaaatccaa accaggcaat ctggccctcc ttattcaccc   3000

tctcatacca ccagtgctac ccattataac ctgtgttcac ttcgcttatt actgtggccc   3060

ttctggtgac tacaacataa cactgagtat gaactgagga attaaccact gaaagagaca   3120

aagcacacct aaataatgat gaacaaatca agacctacaa gaaatgaaca catagatgct   3180

ttttaagtgt cattagttat cggaatcaaa gaatttgagg tggtgacaac tggggattat   3240

ctgtaactcc ccaaatttac tgttcttgaa tgacattctc aaactattta ttaatgagtt   3300

agtctcatcc ctgctttctg tttcctctct ctgcatcttc tcttggcata ggaagttatt   3360

ttactcatgc tatgtttttt aatagaagct ttacaaaaaa agatgcattc ccttcctgtt   3420

cacactctta ccatgttttt gttcttcctt aagaatgatt gtgtgtgtgt gtgtgtgtgt   3480

gtgtaagtgt gtaagtgtaa catcatgggt tttctttctt cacttgtaaa gttttatcta   3540

gaaatacttt tacaggttat gttgaggtac acaaagataa tgttctaaga ttgtgtattg   3600

gatttggatt tgtgtgtgtg tgtgtgtgtg tgtgtgttta aagcatttga taaggtttaa   3660

atgtttttta tacagagatt tttgttcatt aaactcaatc tgcatcatgg tctaa        3715


<210>  731
<211>  3431
<212>  DNA
<213>  Human

<400>  731
gggggaggag ggcggtcgtc cggggttagg ttgagggggg gcgtcggtcc gttctgggcg     60

ggggatgact cacagcccat cccatctccc agacgccgcc cgcccgcgca gtgctagctc    120

catggcttag cggaggaggc ggcagtggcg agctgggggg aggggggact cttattttgt    180

tagggggacc gggccgaggc ccgaccggcc tggcagggct cgcccggggc cgggcgtcat    240

gtctcatgcg gccgaaccag ctcgggatgg cgtagaggcc agcgcggagg gccctcgagc    300

cgtgttcgtg ctgttggagg agcgcaggcc ggccgactcg gctcagctgc tcagcctgaa    360

ctctttgctt ccggaatccg ggattgttgc tgacatagaa ttagaaaacg tccttgatcc    420

tgacagcttc tacgagctca aaagccaacc cttacccctt cgctcaagcc tcccaatatc    480

actgcaggcc acaccagcca ccccagctac actctctgca tcgtcttctg cagggggctc    540

caggacccct gccatgtcgt catcttcttc atcgagggtc ttgctgcggc agcagctaat    600

gcgggcccag gcgcaggagc aggagaggcg tgagcgtcgg gaacaggccg ccgcggctcc    660

cttccccagt cctgcacctg cctctcctgc catctctgtg gttggcgtct ctgctggggg    720

ccacacattg agccgtccac cccctgctca ggtgcccagg gaggtgctca aggtgcagac    780

ccatctggag aacccaacgc gctaccacct gcagcaggcg cgccggcagc aggtgaaaca    840

gtacctgtcc accacactcg ggcccaagct ggcttcccag gccctcaccc caccgccggg    900

gcccgcaagt gcccagccac tgcctgcccc tgaggctgcc cacactaccg gccccacagg    960

cagtgcgccc aacagcccca tggcgctgct caccatcggg tccagctcag agaaggagat   1020

tgatgatgtc attgatgaga tcatcagcct ggagtccagt tacaatgatg aaatgctcag   1080

ctatctgccc ggaggcacca caggactgca gctccccagc acgctgcctg tgtcagggaa   1140

tctgcttgat gtgtacagta gtcaaggcgt ggccacacca gccatcactg tcagcaactc   1200

ctgcccagct gagctgccca acatcaaacg ggagatctct gagaccgagg caaaggccct   1260

tttgaaggaa cggcagaaga aagacaatca caacctaatt gagcgtcgca ggcgattcaa   1320

cattaacgac aggatcaagg aactgggcac tctcatccct aagtccagtg acccggagat   1380

gcgctggaac aagggcacca tcctgaaggc ctctgtggat tatatccgca agctgcagaa   1440

ggagcagcag cgctccaaag acctggagag ccggcagcga tccctggagc aggccaaccg   1500

cagcctgcag ctccgaattc aggaactaga actgcaggcc cagatccatg gcctgccagt   1560

acctcccact ccagggctgc tttccttggc cacgacttcg gcttctgaca gcctcaagcc   1620

agagcagctg gacattgagg aggagggcag gccaggcgca gcaacgttcc atgtaggggg   1680

gggacctgcc cagaatgctc cccatcagca gccccctgca ccgccctcag atgcccttct   1740

ggacctgcac tttcccagcg accacctggg ggacctggga gaccccttcc acctggggct   1800

ggaggacatt ctgatggagg aggaggaggg ggtggtggga ggactgtcgg ggggtgccct   1860

gtccccactg cgggctgcct ccgatcccct gctctcttca gtgtcccctg ctgtctccaa   1920

ggccagcagc cgccgcagca gcttcagcat ggaagaggag tcctgatcag gcctcacccc   1980

tcccctggga ctttcccacc caggaaagga ggaccagtca ggatgaggcc ccgccttttc   2040

ccccaccctc ccatgagact gccctgccca ggtatcctgg gggaagagga gatgtgatca   2100

ggccccaccc ctgtaatcag gcaaggagga ggagtcagat gaggccctgc accttcccca   2160

aaggaaccgc ccagtgcagg tatttcagaa ggagaaggct ggagaaggac atgagatcag   2220

ggcctgcccc ctggggatca cagcctcacc cctgcccctg tgggactcat ccttgcccag   2280

gtgagggaag gagacaggat gaggtctcga ccctgtcccc tagggactgt cctagccagg   2340

tctcctggga aagggagatg tcaggatgtt gctccatcct ttgtcttgga accaccagtc   2400

tagtccgtcc tggcacagaa gaggagtcaa gtaatggagg tcccagccct gggggtttaa   2460

gctctgcccc ttccccatga accctgccct gctctgccca ggcaaggaac agaagtgagg   2520

atgagaccca gccccttccc ctgggaactc tcctggcctt ctaggaatgg aggagccagg   2580

ccccacccct tccctatagg aacagcccag cacaggtatt tcaggtgtga aagaatcagt   2640

aggaccaggc caccgctagt gcttgtggag atcacagccc cacccttgtc cctcagcaac   2700

atcccatcta agcattccac actgcaggga ggagtggtac ttaagctccc ctgccttaac   2760

ctgggaccaa cctgacctaa cctaggaggg ctctgagcca accttgctct tggggaaggg   2820

gacagattat gaaatttcat ggatgaattt tccagaccta tatctggagt gagaggcccc   2880

cacccttggg cagagtcctg ccttcttcct tgaggggcag tttgggaagg tgatgggtat   2940

tagtggggga ctgagttcag gttaccagaa ccagtacctc agtattcttt ttcaacatgt   3000

agggcaagag gatgaaggaa ggggctatcc tgggacctcc ccagcccagg aaaaactgga   3060

agccttcccc cagcaaggca gaagcttgga ggagggttgt aaaagcatat tgtaccccct   3120

catttgttta tctgattttt ttattgctcc gcatactgag aatctaggcc accccaacct   3180

ctgttcccca cccagttctt catttggagg aatcacccca tttcagagtt atcaagagac   3240

actcccccct ccattcccac ccctcatacc tacacccaag gttgtcagct ttggattgct   3300

ggggccaggc cccatggagg gtatactgag gggtctatag gtttgtgatt aaaataataa   3360

aagctaggcg tgtttgatgc gcttttaact ttgaaaaaaa aaaaaaaaaa aaaaaaaaaa   3420

aaaaaaaaaa a                                                        3431


<210>  732
<211>  2104
<212>  DNA
<213>  Human

<400>  732
gtccctcccc tctccgcagg ccccgccgcc gccgccatct ttgttggggg cagccaggcc     60

tggctcgaga tgccgaagtc gtgcgcggcc cggcagtgct gcaaccgcta cagcagccgc    120

aggaagcagc tcaccttcca ccggtttccg ttcagccgcc cggagctgct gaaggaatgg    180

gtgctgaaca tcggccgggg caacttcaag cccaagcagc acacggtcat ctgctccgag    240

cacttccggc cagagtgctt cagcgccttt ggaaaccgca agaacctaaa gcacaatgcc    300

gtgcccacgg tgttcgcctt tcaggacccc acacagcagg tgagggagaa cacagaccct    360

gccagtgaga gaggaaatgc cagctcttct cagaaagaaa agacttcacc ctgccgttcc    420

caggtcctcc ctgaggcggg ggccggagag gacagtcctg ggagaaacat ggacactgca    480

cttgaagagc ttcagttgcc cccaaatgcc gaaggccacg taaaacaggc aatgttgttt    540

aatgtagaaa atggaacccc agcttcacgt gaagccttgt ggttgagtga ggagtgaagg    600

atggggagga ggcctctggg gaaggggttc cctccctcct gaagatgaac acacaataca    660

cggaagagcg ccagcctctg ctttcaggaa aggtttattg tggtgagtgc cttctgtaca    720

gtcgactgca aatgaaacgc agaggatggg tgcccagaag cacctgcggc agaggcgcac    780

gggaagcccg gggcccaggc tcatgcaaca cgacgctcac cgcggctcgg gccgtggggc    840

cgtcagagaa acctttttaa aaaatggaga tgaatgttac agaattggac aacccgaact    900

gcttttcaaa accagaggaa ggaggttctt agccgttact cagataccag tgctggggag    960

ggaggcctga cttcagcaac agctgtgggt gggctggagg ccggcgcagc ttggggcccc   1020

ccgcgccagc tgtctcagcc accacctgtg cggcgcttgc tccgaggggt cagcaagagc   1080

aactgatggc tgccacttcc aggccccgag agacaggcct cacgtaactt tactgcagcc   1140

gaggtccagg ccgtggaggg ggtcctagct ccgctgcatt ctgcatccca agtgggcacg   1200

tggaggaagg gtctgaagga aggctccgga gcacaggccc tggtgttcct gtgaggacgc   1260

tggacctgca ggagcgggga gctgcagtgc cacctgctgg gtaccacggg ccgggcctgg   1320

ggtccacgcc tttgggttgg gtgtgtctga tgtcttgcca agcgcctggt cctgtcctct   1380

tgagctgccc ttgcccagca ctgcactctg gaggtgggtg gtgcaggcgg tggagggaca   1440

caggccagct caagcccgct ggtggcaggg cgttttccca ccgggatacg ggaagccacc   1500

tgtgtcaggg ctaggccctg ggatcgggag ttacactacc ctgtcccaag ccgagggggc   1560

cggtggaatg acttgagcag ctctgggagt ggggaaaaaa gacgactaat ttccaaaccc   1620

gtttgttctc agataaaaag cagttttata aacccgcaat ctgctccaga ttcaagcagt   1680

aatatttcag caagaggagg tggtcatggg aagccagcac agcagaggct ccctgaccgg   1740

gaggcctgcc tgcttttcag gttgtttccc atgttcagcg tggactgcag aagtggctca   1800

cgctcctgtg gtgagggcag ggtgctccac agacacctcc agacccagcc aagaactaca   1860

gggcggcggg ctgcggtcag cacgtgtgct cgggacacag cggagtcagg gccagagccc   1920

ttccctccag gaactgatcc ttgggaaaac agccatgggc caggctgcag tctggttccc   1980

agtggggctg cctcagtcct acccccagca ccctcaaaag ctggggtgtc tgcatgtccc   2040

ttcacataat tgataatggt accaccttct ataataataa tataaaataa aaacaaaaaa   2100

aaaa                                                                2104


<210>  733
<211>  2261
<212>  DNA
<213>  Human

<400>  733
ttcgcggtgc caccgccccg cccacgcctc ctcgccggcc tccgagtgcg tcacgtgacg     60

ggtcggtggc gctggcggtt gctgtcagct gattcccggg gttggtggca gcggcggtag    120

cagcaatgga ctttctcctg gggaacccgt tcagctctcc agtgggacag cgcatcgaga    180

aagccacaga tggctccctg cagagcgagg actgggccct caacatggag atctgcgaca    240

tcatcaacga gacggaggaa ggtcccaaag atgccctccg agcagtaaag aagagaatcg    300

tggggaataa gaacttccac gaggtgatgc tggctctcac agtcttagaa acctgtgtca    360

agaactgcgg gcaccgcttc cacgtgctgg tggccagcca ggacttcgtg gagagtgtgc    420

tggtgaggac catcctgccc aagaacaacc cacccaccat cgtgcatgac aaagtgctca    480

acctcatcca gaccgtgttc aactcagaga cacaatcagg acaggattct gtgggcactg    540

actccagcca gcaagaggac tctggccagc atgctgcccc tctgcccgcc ccgcccatac    600

tctccggtga cacgcccata gcaccaaccc cggaacagat tgggaagctg cgcagtgagc    660

tggagatggt gagtgggaac gtgagggtga tgtcggagat gctgacggag ctggtgccca    720

cccaggccga gcccgcagac ctggagctgc tgcaggagct caaccgcacg tgccgagcca    780

tgcagcagcg ggtcctggag ctcatccctc agatcgccaa tgagcagctg acagaggagc    840

tgctcatcgt caatgacaat ctcaacaatg tgttcctgcg ccatgaacgg tttgaacggt    900

tccgaacagg ccagaccacc aaggccccaa gtgaggccga gccggcagct gacctgatcg    960

acatgggccc tgacccagca gccaccggca acctctcatc ccagctggca ggaatgaacc   1020

tgggctccag cagtgtgaga gctggcctgc agtctctgga ggcctctggt cgactggaag   1080

atgagtttga catgtttgcg ctgacacggg gcagctcact ggctgaccaa cggaaagagg   1140

taaaatacga agccccccaa gcaacagacg gcctggctgg agccctggac gcccggcagc   1200

agagcactgg cgcgatccca gtcacccagg cctgcctcat ggaggacatc gagcagtggc   1260

tgtccactga cgtgggtaat gatgcggaag agcctaaggg ggtcaccagc gaagaatttg   1320

acaaattcct ggaagaacgg gccaaagccg cggaccgatt gcccaacctc tccagcccct   1380

cagctgaggg gcccccgggt cccccatctg gcccagcgcc ccggaagaag acccaggaga   1440

aagatgatga catgctgttt gccttatgag tgtggggtct ggcaccctgc agcccaggtc   1500

cccactgctc tcacaccctt aggctgggac ctccctccct cctctggtgt taaggctgct   1560

ttgggggtgg cttgttaccc ccttttcctc ctctttgaag acggagctgc cccagctgtg   1620

gctgggggtg tggaggcagt gggatgaact gggggacagg tctgcgctgc agtgggatct   1680

ggctgctctg cctcctttcc caccccagct gaccatgaga ctttgctgag aagtggaggc   1740

cccaggacag gctggctggc tggctggctg cttgacccag tgtgactctc cttcactgag   1800

tgataccctg ctccgggccc atgccccaag gagcccttca gagcccacac tgccagtcga   1860

ggcctggctg gaggctggcc acagtggaaa ttctgccgag cctcttgtcc cttccctgct   1920

ctgctgcatg gggccccatg gctttggctg gccactgagg gtagggtgtg gaggtgtgga   1980

ggccccctga ggagctgcgg cggcccaggt acgaagctgc aactctgcgc gcagtgggcg   2040

agatctcatc agccccaggc tgcaggtgag gcttcagggg atgctggggc cccactgccc   2100

ctccgctgcc ttgccctcca tccttcctct gttccttctg gccgggcacc acagcactgg   2160

ggctcacctc ttggttgatc ctcttgtact gggagaggtg ccttttgtat ccccaattaa   2220

aggtagaaaa ccaccctgct agcagcattg tcaaaaaaaa a                       2261


<210>  734
<211>  1566
<212>  DNA
<213>  Human

<400>  734
ggggcgccgc catcgcacag agaggcctgg gcggggcgga ccggcgctgg gcagccagga     60

cagccgcggc agccgggtcc gcagggcagc agccggcctc tcccactgca gccctcccgc    120

ccgcctaccg tccggcgcga tggcggggag tagctcgctg gaggcggtgc gcaggaagat    180

ccggagcctg caggagcagg cggacgccgc tgaggagcgc gcgggcaccc tgcagcgcga    240

gctggaccac gagaggaagc tgagggagac cgctgaagcc gacgtagctt ctctgaacag    300

acgcatccag ctggttgagg aagagttgga tcgtgcccag gagcgtctgg caacagcttt    360

gcagaagctg gaggaagctg agaaggcagc agatgagagt gagagaggca tgaaagtcat    420

tgagagtcga gcccaaaaag atgaagaaaa aatggaaatt caggagatcc aactgaaaga    480

ggccaagcac attgctgaag atgccgaccg caaatatgaa gaggtggccc gtaagctggt    540

catcattgag agcgacctgg aacgtgcaga ggagcgggct gagctctcag aaggcaaatg    600

tgccgagctt gaagaagaat tgaaaactgt gacgaacaac ttgaagtcac tggaggctca    660

ggctgagaag tactcgcaga aggaagacag atatgaggaa gagatcaagg tcctttccga    720

caagctgaag gaggctgaga ctcgggctga gtttgcggag aggtcagtaa ctaaattgga    780

gaaaagcatt gatgacttag aagatcaact ctaccagcaa cttgagcaaa atcgccgcct    840

cactaatgaa ctaaagctgg ccctgaatga ggattaaact taagagtgaa aaaacttggg    900

ctgaattcta ggcgtggagc ccatgtgcag aaaatctaag actgtcctac cttcaactaa    960

tagagttgaa aacagttgct ttctgcagaa atgcaaatgc aaggaattgg ctgaaaggct   1020

ggccttgcct gcttgtttct ctatatggct ggaataatta cgttctcttt aatcacaaaa   1080

cagcttttat ggtagaatac ttatatcaat tcagcactgc tccttgaaat agcaggtcct   1140

cttgtttgaa ctgataaata atgaggagcc cccccaaaaa atgttttcta tttcctgaca   1200

gccatgagtc ctactttaag tatgtatata tatatatata tgtgtgtgtg tgtgtgtgtg   1260

tatatattcc tatcagatac tcatattcct aacttctaaa tatctggtat agtgtttgaa   1320

atatgattaa atgtacctat gcttgggcaa aatagctttt gaaaacagga actcatgcca   1380

gaagcccctg gttgtctgaa aggtatgctt tactcagtct aatggtgctg ttggagtctg   1440

gggagaatgt catgctaata aatagaacac tataaaaata ttaagagaat gtcctaatga   1500

agtgtgcatg aaacatgttg acaatttttt atgagcaaca gaaataaatc attttaaaag   1560

ttctca                                                              1566


<210>  735
<211>  1884
<212>  DNA
<213>  Human

<400>  735
gtagcggtct ccgcagccag gattggcgcc cgcgcgggcc ttcgagcccc gcccgcagag     60

ccccgcccgc aaagccccac cccggtgcgc gggtatggcg gccagcctgt ggatgggcga    120

cctggaaccc tacatggatg agaacttcat ctccagagcc tttgccacca tgggggagac    180

cgtaatgagc gtcaaaatta tccgaaaccg cctcactggg atcccagctg gctactgctt    240

tgtagaattt gcagatttgg ccacagctga gaagtgtttg cataaaatta atgggaaacc    300

ccttccagga gccacacctg cgaaacgttt taaactgaac tatgccactt acgggaaaca    360

accagataac agccctgagt attccctctt tgtgggggac ctgaccccgg acgtggatga    420

tggcatgctg tatgaattct tcgtcaaagt ctacccctcc tgtcggggag gcaaggtggt    480

tttggaccag acaggcgtgt ctaagggtta tggttttgtg aaattcacag atgaactgga    540

acagaagcga gccctgacgg agtgccaggg agcagtggga ctggggtcta agcctgtgcg    600

gctgagcgtg gcaatcccta aagcgagccg tgtaaagcca gtggaatata gtcagatgta    660

cagttatagc tacaaccagt attatcagca gtaccagaac tactatgctc agtggggcta    720

tgaccagaac acaggcagct acagctacag ttacccccag tatggctata cccagagcac    780

catgcagaca tatgaagaag ttggagatga tgcattggaa gaccccatgc cacagctgga    840

tgtgactgag gccaacaagg agttcatgga acagagtgag gagctgtatg acgctctgat    900

ggactgtcac tggcagcccc tggacacagt gtcttcagag atccctgcca tgatgtagcc    960

aggccaaagg acaagccagg ttgcatgatg tgagggagat gagagactcc tttttaaaaa   1020

ttgtgaaacc tttttggaaa tatgatttgt aagattttaa taatgactgt ttttggagat   1080

catgaatgtt tctacaacac tgctgcattc atttgaccat ttgagtttga agaccaaggg   1140

aacaactttt aaacaaggtt caaattggtt tccttcacag gaatcctttg tccaggtagt   1200

tatccacata ggacagtttg ggattatcca aaactgggat gagcagcttg ggataattca   1260

cacactaaag cctgagttca aggtttctca gttgacaggt aggtatgtaa atcagggttc   1320

tctggagtat ttgtaggacc tgccatattt gagtcctaac ttggtgcaag tctggcagct   1380

aggtagaaaa ggcactctag caggtgtggt aggagcacgc cccagaaggt agaatgtggt   1440

ggggtgtgat ggaacaggcc agttggccta agaattagta cttgctctaa taatgggttt   1500

catctatttt catgagttgc agcatctgca tatacaaggc ctggatcact ttaggatcaa   1560

tattttgaca cgggagaagg cagctcagaa aggattaagg aagatagctc aaagccaaag   1620

cagaccctcc gtgtgaactt tatactgctc acttccgtgt ttcccaagta aatggggaaa   1680

ctgtccaacc ttgtcatgtg ttgggactta ctgcttgagg caaagcattc atcctacatc   1740

ataaaaaatc tccaaagatc tctttaaggg ctgggcatgg tggctcactt tgggagatgg   1800

attgcttgag ctcgggaaga gaccagttcg gtctctacaa aaaaatacaa acacaaatat   1860

acttttaaaa aaaaaaaaaa aaaa                                          1884


<210>  736
<211>  3662
<212>  DNA
<213>  Human

<400>  736
gggcgcggga tcaggggccc tgggagggcg agcgcggcga ggggcgcatg cagggccccg     60

acgcgccact gctcctgagc gcgagggagc tggggcccgg gcgccggggc tcggcctcct    120

ggtaccgcca ggagggcggc gcggtgtgca actggctgcg gaagccgcag ccgctcgagc    180

cacgcaccag tttcccctcg gcgcgccgct ccgagttccg tccacccagg aggctgccat    240

gggccggccc tgcctccgcc cagtccgagg agggtcacgc aggcggcaga tgccaggcgg    300

gcagccccgc ccctgcgcgc cgcctcagcg gcgccttcaa gacgctggtc ccaggcaccc    360

acgcccaggg cgcctcggat acccaccccc tcggcccccc gcacaccccg gtcctcgacc    420

cctctccgca ggatggtttc ccggtcctct ggcgaggatc ctccaaggcg tctcacatga    480

accggctcag aaacgccaaa atctacgtgg agagagctgt caagcagaag aagatcttta    540

caatccaagg ctgctacccg gtgatccggt gtctcttgcg ccggaggggc tgggtggaga    600

agaagatggt ccatcgctca ggccccaccc tgctgccacc ccagaaggat ctggatagct    660

cagcgatggg tgacagtgac accactgagg atgaggatga agatgaggac gaggagttcc    720

agccatcaca gctgttcgac ttcgatgatt tactgaaatt tgatgaccta gatggaacac    780

atgctctgat ggtgggtcta tgtctcaatc tccggaattt gccgtggttt gatgaggttg    840

atgccaactc cttcttccca cgctgctact gcctgggggc tgaggatgac aaaaaagcct    900

tcatagagga cttctggctg actgctgccc gcaacgttct caagctggtg gtgaagtctg    960

agtggaagtc ataccctatt caggcagtag aggaagaggc ctcaggagac aagcagccca   1020

agaaacagga gaaaaaccca gtgttggtgt ccccagagtt tgtggatgaa gctctgtgtg   1080

cgtgcgagga gtaccttagc aacttggccc acatggacat cgacaaggac ctggaggccc   1140

cgctgtacct cacccccgag ggctggtccc tcttcctcca gcgctactac caagtggtcc   1200

acgaaggggc agaactcagg cacctcgaca ctcaggtcca gcgctgtgag gacatcctgc   1260

agcagctgca ggccgtggta ccccagatag acatggaagg ggatcgcaac atctggatcg   1320

tgaagccagg agccaagtcc cgcggacgag gcatcatgtg catggaccac ctggaggaga   1380

tgctgaagct ggtgaacggc aaccccgtgg tgatgaagga cggcaagtgg gtggtgcaga   1440

agtatattga gcggcccctc ctcatctttg gcaccaagtt tgacctcaga cagtggttcc   1500

tggtaactga ctggaaccca cttaccgtgt ggttctaccg cgacagctat atccgctttt   1560

ccacgcagcc cttctccctg aagaacctgg acaactcagt gcacctgtgc aacaactcca   1620

tccagaagca cctggagaac tcatgccatc ggcatccact gcttccgcca gacaacatgt   1680

ggtctagcca gaggttccag gcccacctgc aggagatggg tgccccaaat gcttggtcca   1740

ccatcatcgt gcctggcatg aaggatgctg tgatccacgc acttcagacc tcccaggaca   1800

ccgtgcagtg tcggaaggcc agctttgagc tctatggcgc tgacttcgtg ttcggggagg   1860

acttccagcc ctggctgatt gagatcaacg ccagccccac gatggcaccc tccacagcag   1920

tcactgcccg gctctgtgct ggcgtgcaag ctgacaccct gcgcgtggtc attgaccgga   1980

tgctggaccg caactgtgac acaggagcct ttgagctcat ctataagcag cctgctgtgg   2040

aggtgcctca atatgtgggc atccggctcc tggtagaggg cttcaccatc aagaagccca   2100

tggcgatgtg tcatcggcgg atgggggtcc gcccagcagt ccctctgctg acccagcgag   2160

gctctgggga agcccgtcac cacttcccca gcctccacac caaggcccag ctgccttctc   2220

cccatgtact ccgacaccag ggccaggtcc tcagacgaca gcacagcaag ctggtgggca   2280

ctaaggccct gtcgaccaca ggcaaggcct tgaggactct acccacggct aaggtcttca   2340

tttccctccc accgaacctt gatttcaagg tggcacccag catcctgaag ccaagaaagg   2400

ctcctgctct cctgtgcctc cgaggccccc agctggaagt gccttgttgc ctctgccctt   2460

tgaagtcgga acaattccta gcacctgtcg gaaggtcaag gccaaaggca aattcaaggc   2520

cagactgtga caaacccagg gctgaggcct gccccatgaa gaggctgagc cccctgaaac   2580

ccctgcccct tgttggtaca ttccagaggc gcaggggcct gggggatatg aagctaggga   2640

agcccctgct tcgattcccc actgcccttg tcctggatcc aacaccaaat aaaaagaaac   2700

aagtgaagta tttggggctt gactccattg ctgttggagg gtcaagagtg gatggggcga   2760

ggccgtgtac cccagggtcc acagcaagag cctgaggcca tcagcagctc ctccgtgcag   2820

cgaggcccag aattcccacc taaggacaga catggggctt cctatttagg gactccccca   2880

gcatctccga tccaggggtg gggagcgtga gccttcactt tacagatgaa gaaactgagt   2940

ctgaaagagg aggcatggct tacccaagat cacgtggcag tgagtcgacg cagggacata   3000

ttgccagaac tgccgagcac tgggagcccc ccaaccccag agaacaagcc aagctagcag   3060

aatgacacct accgggcata ggaacgttaa tgccatgaga caggggaagg aattggcctt   3120

gcctaaacct cagcccttct gcagagggca tgggtctatc ccttcttcag caaggggcca   3180

aggtcaccta aaaatgaaac atccaataag ccacacccac ctgaagaaaa gtgtggcact   3240

gcttagttgt agtgggttga actgtggtcc cctgaaaaga gatgtctact tggaccctgt   3300

gaatgtgacc ttatgtggga aaagagtctt tgtagctggg tatggtggct cacacctgtt   3360

atcccagcac tttgagaggc caaggcagga gatcgcttga gcccgcaagt tcaagaccag   3420

tctgggcaac atggtgaaac cgtttctaca gaaaattagc tgggtgtggt ggcacacacc   3480

tgtagtccta gctactcggg aggcctaggt gggaggatta cctgagcctg ggaagatcaa   3540

aactgtggtg agctgtgatc acgccactgc gctctgagcc tgggagacag agtgaaaccc   3600

taaatcaaaa aaaaaaaaaa aggtctttgc agatgtaaat aaatttaaga tcttaaatga   3660

ga                                                                  3662


<210>  737
<211>  4940
<212>  DNA
<213>  Human

<400>  737
cggggcccgg gaggggcgga ggctggggcc agacgcctcg ccgcctccgc ctcggcgaat     60

agcagcgcgc tgcccgcccg gattggagca gcagcatcac gctgacctct gcctgggatg    120

taaaccggac cagccgctgc gggcaaagga aggctcttgg ctccttcggg aaacccagcc    180

ccgtcaccgg gctccgagcg gctcgcaggc gagcgacagc ggcctcagcc ccggcagcgc    240

ccagcggcgg ctgcggaaag cggagggagt ccgacgcggg cgcgggcggg gagcgtgcgt    300

ccgttcgcac aggcagcggg aggaggggcg gcgcgaacca tggccgggga cagcgagcag    360

accctgcaga accaccagca gcccaacggc ggcgagccct tccttatagg cgtcagcggg    420

ggaacagcta gcggcaagtc ttccgtgtgt gctaagatcg tgcagctcct ggggcagaat    480

gaggtggact atcgccagaa gcaggtggtc atcctgagcc aggatagctt ctaccgtgtc    540

cttacctcgg agcagaaggc caaagccctg aagggccagt tcaactttga ccacccggat    600

gcctttgaca atgaactcat tctcaaaaca ctcaaagaaa tcactgaagg gaaaacagtc    660

cagatccccg tgtatgactt tgtctcccat tcccggaagg aggagacagt tactgtctat    720

cccgcagacg tggtgctctt tgaagggatc ctggccttct actcccagga ggtacgagac    780

ctgttccaga tgaagctttt tgtggataca gatgcggaca cccggctctc acgcagagta    840

ttaagggaca tcagcgagag aggcagggat cttgagcaga ttttatctca gtacattacg    900

ttcgtcaagc ctgcctttga ggaattctgc ttgccaacaa agaagtatgc tgatgtgatc    960

atccctagag gtgcagataa tctggtggcc atcaacctca tcgtgcagca catccaggac   1020

atcctgaatg gagggccctc caaacggcag accaatggct gtctcaacgg ctacacccct   1080

tcacgcaaga ggcaggcatc ggagtccagc agcaggccgc attgacccgt ctccatcgga   1140

ccccagcccc tatctccaag agacagagga ggggtcagga ggcactgctc atctgtacat   1200

actgtttcct atgacattac tgtatttaag aaaacaccat ggagatgaaa tgcctttgat   1260

tttttttttc tttttgtact ttggaacgac aaaatgaaac agaacttgac cctgagctta   1320

aataacaaaa ctgtgccaac tactactggt gatgcctaat tatgaatcca acgtgtaacc   1380

agttataaat acatatatat ataaaaaagg atctattttt gtgtaaatgt acaaatactg   1440

taaagctgtt tgccataagt attttgcagg agggtctgta cttgagtgtt ttaggactgg   1500

agctggaatt tcaccaaggg gaaattgcct gttgtgtccc agggtgggga ggctcgggca   1560

tctgtgagag acagggaggg tggctaaggt ccagttgctt ttgagtgccc cgtggaactt   1620

gatgggaatg gggttggaaa accttgattg cctcctctgt cacatgccac tcttggagct   1680

ggagcttagt gatatgtcaa tgagagatac tcttgtcttt tttttttttc ttttcttttt   1740

tttttttgag ttgaaattag gtaaaatctc aactcaaaaa tcaaactcag ggaagaggcc   1800

cactgaggag aacaagtctt ctgcattttc ttcctgccct gctcccacct tctcgcctct   1860

ggctgcttgg atagcttggt gactccttcc tcaccctcct gcttctctgt ctctccaaga   1920

agccagagct gcctctttcc ttccctggaa gagattttat gggatcgctt cctgatagaa   1980

gatgggaagg agagggcaga actttgcctg ctgtcatatc tgaagaatca ctggttcttt   2040

ctgcatccca ggggcgtaac tgatctgact ccttgggctt tttcctgtat tgtggaatat   2100

agagtggacc attgcaggct gggtgtgggt gagggcttcg gtaactgatg ccggcagcag   2160

cgcctcatgg agtggcaggg gagctctgtc tgtggagggg tagtagtttc cgcttcctgg   2220

aggtttgcag tgaggtgagg agagtaactt tggtcaggga ttctcactag cagcgtcatg   2280

gccaggatgc tttacttatt tgcaatacca cctagtggat atggcaactg cagagcataa   2340

aaggggctcg gaaaagcagt ttttacaaag tatttaaaag gagagtattt aaatcatagg   2400

tacctaagtt ggagcctgag gttgaaatat ttggggtgga gatttctagc tttcctgaga   2460

gctgctgctt ggtggtagtg ttttctctgg aagtacagat tcctgacatt ctgggtggag   2520

gggagcccaa gtgagcctga aggagttctg attatagagt cccgagcctc agtttctgac   2580

tgcagaagag ccagagatgt tcatttcatt gttgaccacc ctagtgcttg gtggactgtg   2640

cccttagcta tcccactgtg gctgccattg ccagaaacat tttggagaac cttttcttcc   2700

cattgctctc agagcctgtt cgagccattc aggtaaattg gtctccatta ttacctggtc   2760

acaccagatt ttcccccaga ctcagcacca tccagtctga ttccccgttt ctgggctcag   2820

tttgactcta aatctgtttt gctattttaa aaagtcaaac ctggtcccca gcagagcttg   2880

ccacccggag actttcagga gaccgtgcag gctctgaagg gagctcccag tcacagcagc   2940

cgcctacttg gagcaaggga aggctcccaa gatgcctcct ttgaaagccg gtgctcacca   3000

agatcagttc aggatcaatc attatccttg tagtcatgcc ttgatcagtt ctgagatgaa   3060

gcagggaatg caggcctggg ttagtatcct gaggacacag ggcccctggc cttgatggca   3120

ctgggctgtg ctcaggtgaa gcccacccgt gtctgggaga gccttggctt ttcagtgggc   3180

agcatgctca actttacttg aagctcccag gtgccaaacc atttagtgcc ttggctgttt   3240

atcccactgc cttggaagat ggactcctct catctctgag cctttaccta gctgcttcct   3300

catctacctg tggtgttggg accaagcctc caatatctct gaatagccca ctcctagctt   3360

ggaaacagct ataagggctg ccctgcccct tgtcaaatga tcaccaattc ttggtggctt   3420

ggctggggac aatgaacagt gtctgctggg gtctgtgaca cactgtttct ggaacaagga   3480

agggatggaa ggctctaccc ctccgtggca gcccagcatt tggccaactc tgtatctgaa   3540

cttgagcttt ctatggaaca aacaatggtc ttagtttttt aagagcctct gggtctctga   3600

ttccatggag agtcaggagt agaattagtg gaccagaaac catgacattt gccatctagg   3660

tactctgctg ttcagggtgg aggcacagat gagcagagtg gggtgatgtt ggttgtatgt   3720

gcatagaagt cccctggctc cagagccatc cagtggtgct tggttctctc ttcctgccca   3780

ggtattgtgt gtggaccaag tgtttaggaa acaagcatag aagcattatg tcacaggaag   3840

gcctggcctc tcactccttc acactaatga gccttctact gacccaagtt tctttttctc   3900

gggcagcctg ggaccactat gagcagagag atgggagtct gtgtaagaag gatgcaagta   3960

tcctttgatt tggagtggac agagcaggtc cttgcaaagg cagtgggtta aacaacggga   4020

tgtctgtggg acaggccagg gaaggagggc agagacaggg tctccagttc accttgccgc   4080

agaactagcc taatcatccc tgcttctggt cttggccact tggcaatcat ggggaagttg   4140

actccccgcc tcacttgggc ttggagctgg atacttgtgg ccacgcccag gataggttgc   4200

cagagtttca ttaggccgct gggtcgggct ggaggcttgt gtacacctcg gagcagtcgg   4260

gcagcaggag ggccggaagc ctggttggtt tgtatatgac ctctcttgcc cttgtgcact   4320

ttccttgatt tagcaacctt gacctgcact ggccctcaca gctgttggag ggaagtagcc   4380

tcttgcaggg aaatattttc ccctgccctg gaatctccta tgtgcctgtt aaagattcca   4440

gggccaagaa ctcggcaggc tgaggagcag ctaggtaggt gggttatgcg gttcaggact   4500

gcttctggaa gggactgcct gtacttctgt accaccgttg ccctttacac tttgctcagg   4560

gcggggtggg ggaagcattc aaacaaaaca aggaagggaa ctgtctggca aagcataagt   4620

ggatgcatcc agagctcagt cccctttaat cttttgtctc tgggcgttct gctgccttcc   4680

tcataccggg gactggcatt ccaggtcagc ttggctgtgg tcttagaggc agggagtgcc   4740

tacccagtcc tgcctcagga gcagggtgag tagctaaata cagacttagg cttttttttc   4800

ccccctttta agatgcttgc tcctctccct tttcttttta ccaccctacc tttattgtta   4860

gtggttacaa agtgaccaca tattatgtac tttgctgtaa ataaagacag acaaaaaggc   4920

aaaaaaaaaa aaaaaaaaaa                                               4940


<210>  738
<211>  2201
<212>  DNA
<213>  Human

<400>  738
gtagttctga catgtttagg gagtggagtt ctgctaaaaa gactagacta ggacattttt     60

aggcaagatg gggaaactaa tccagaaaaa gaaaccgcac cgctacttag cccctggctc    120

cggacctgcc tttctttttt aaatcactct tgcataagct gccgctcgcg ataaggtgcc    180

aaaaactgtt ccgcccctct aaggagagcg tgccctcact caagatggca cctagagagc    240

ttcatacctg gtacgctgct gattggatga aggacagagg gcttccggga gttttcaagc    300

cgactgtgtg gcagctgaga ggagttttgc acgtggatcg ccgttcgggt gggcgagatg    360

gagacagccc ccaagccggg caaggatgtc ccgcccaaga aagacaaact tcagaccaag    420

agaaagaaac cccgagaatg gaagaacccg gagtcccagc gcggcttgtc cgggacccaa    480

gatccattcc caggccccgc ccccgtccct gtggaagtgg tccagaagtt ctgtcgcatt    540

gacaaatccc gaaagctacc acattctaaa gccaaaactc gaagccgact tgaggtggct    600

gaagctgagg aagaggaaac aagtatcaaa gctgctcgtt ctgagctgct gcttgctgaa    660

gaacctgggt ttctggaagg ggaggatggg gaagacacag caaagatatg ccaggctgac    720

attgtggagg ctgtggacat tgcaagtgca gccaagcact ttgacttgaa tctgcggcag    780

tttggaccct acagactaaa ctactctcga actggaagac acctggcttt tggagggcgc    840

cgaggtcatg tggctgccct tgattgggta acaaagaagc ttatgtgcga gatcaacgtc    900

atggaggcgg tgcgggacat ccggtttctc cattctgagg cactgcttgc tgttgctcag    960

aaccgctggc tccacatcta tgacaatcag ggcattgagc tccactgtat ccgccgctgt   1020

gaccgagtaa cacggcttga gttcctgccc ttccacttcc tcctggctac agcttcagaa   1080

acagggtttc taacctacct ggatgtgtca gtggggaaga ttgtggcagc tctgaatgct   1140

cgagctgggc ggctcgatgt tatgagtcag aacccttaca atgccgtcat ccatctcgga   1200

cacagcaatg gtactgtgtc tttatggagt ccagctatga aggagccact ggcaaagatt   1260

ctctgtcatc gtggtggggt ccgggctgtg gcagtagatt ctacaggcac gtacatggcc   1320

acctctggcc tagaccacca gctgaagatc tttgacttgc gagggacgta ccagcctctg   1380

agcactcgga ccctgcccca tggagcaggg cacctggcct tctcccagag gggactgctg   1440

gtggcgggaa tgggtgacgt tgtcaacatc tgggcagggc agggcaaggc cagcccaccc   1500

tcccttgaac agccctacct cacccaccgg ctctcaggcc ctgtgcatgg ccttcagttc   1560

tgcccctttg aagatgtgct gggggtgggg cacactgggg gcatcaccag catgctggtc   1620

cctggggccg gtgagcccaa cttcgatggc ctggagagta atccatacag aagccggaag   1680

cagcgccagg agtgggaggt gaaggccctg ctagagaagg tacctgcaga gcttatttgt   1740

ctggacccac gagccctggc cgaggtggat gtcatctccc tggagcaggg aaagaaggag   1800

cagatagaga ggctgggcta tgacccgcag gctaaggctc ccttccagcc aaagccaaag   1860

cagaagggcc gcagctccac ggcaagcctg gtgaagagga agaggaaggt catggatgag   1920

gaacacaggg acaaggtccg gcagagcctt cagcagcagc atcataagga ggcgaaggcc   1980

aagcccacgg gggcccggcc atctgccctg gacagatttg tgcgctgagc cagactccag   2040

ggttgcctgg gaacagtctc tccccaagat cacctgtagg gaaatgagtg ttccctggaa   2100

caaggaggtg ggggcagtgt ggccccttcc ccaactgggg gtggacagct gtctcctggg   2160

gtgggttggt attaaagagg aaagcgattt tttggataat g                       2201


<210>  739
<211>  2247
<212>  DNA
<213>  Human

<400>  739
gttcccctgc agttgtttgg gctgtccctg tggctggttc tggggtgtgc ggccagccat     60

ggagcgctct gggcccagcg aagtgacagg ctcagacgcg tcgggaccgg acccgcagct    120

tgcggtcacc atgggcttca cggggttcgg taaaaaagct cgcacatttg acttggaagc    180

aatgtttgaa caaactcgaa ggacagctgt ggaaagaagt cgcaaaacac tggaagcaag    240

agaaaaagag gaagaaatga acagagagaa agaattaaga agacaaaatg aagatattga    300

gccaacatcc tcaagatcaa atgtggtcag agattgctcc aaatcatctt ccagggatac    360

gagcagcagt gaaagtgaac agagttctga ctcttctgat gatgagttaa ttggccctcc    420

tttaccccct aaaatggtag gaaaaccagt taattttatg gaggaagata tcctcggtcc    480

tttacctcca cctcttaatg aagaagaaga agaagcagag gaagaagaag aggaagagga    540

ggaagaggaa aatcctgttc acaagattcc tgactcgcat gagataacgc tgaagcatgg    600

cactaaaaca gtgtctgctt tgggtctgga tccctcaggt gcccgtttgg tgacaggagg    660

atatgactat gatgttaagt tttgggattt tgctggaatg gatgcttctt ttaaggcatt    720

tcgatccctt cagccctgtg agtgccatca gatcaagtca ttacagtata gtaacacagg    780

agacatgatt cttgttgtat ctggaagctc tcaggccaag gtgattgaca gagatggttt    840

tgaagtaatg gaatgtataa aaggagacca gtatattgtg gacatggcca acaccaaggg    900

tcatacagca atgcttcata ctggctcatg gcatcccaaa ataaagggag aatttatgac    960

ttgctcaaat gatgcgactg tgaggacgtg ggaagttgaa aatccaaaga agcaaaaaag   1020

tgtgtttaaa ccacggacga tgcaaggcaa aaaagtcatt cccactacgt gcacatatag   1080

tagagatgga aacctcatag cagctgcctg ccagaatgga agcatacaga tctgggaccg   1140

aaatttgact gttcatccta agttccacta taaacaggct catgactcgg gcacagacac   1200

ttcttgcgtg actttttcct atgatggtaa tgtccttgcc tctcgtggag gtgacgattc   1260

attaaaatta tgggacatcc gacaatttaa taaaccactt ttttcagcct cgggtcttcc   1320

caccatgttc ccaatgactg actgctgttt cagtccagat gataagctca tagtcactgg   1380

tacatctatt caaagaggat gtggcagcgg caaacttgtt ttctttgagc gtaggacttt   1440

ccaaagggtg tatgaaatag acatcacaga tgcgagtgtt gttcgctgcc tgtggcatcc   1500

aaagctgaac cagatcatgg ttggaactgg aaatggattg gctaaagtct attacgaccc   1560

caacaagagt cagaggggag caaaattatg tgtggttaaa acccagcgga aggcaaaaca   1620

agctgagact ctaactcagg actacatcat cacccctcat gccttgccta tgttccgtga   1680

gccccgccaa cggagtacaa ggaaacagct ggagaaggac agactggatc ccctgaagtc   1740

gcataaacct gaacctcctg tagcaggccc aggtcgtggt ggccgagttg gaacccacgg   1800

gggcactctc tcttcctata ttgtgaagaa cattgctttg gacaagaccg atgacagtaa   1860

tcctcgggaa gccattttgc gtcatgccaa agcagcagaa gacagcccat attgggtttc   1920

tccagcatat tccaagactc agcccaaaac catgtttgcc caagttgaat ctgatgatga   1980

ggaagcaaag aatgagccag aatggaaaaa acgtaaaatt tgaagaatct catttgagag   2040

ctgtttgcat gagtgggagg ggtatgggac aggtttgggt ttttttttta tgctcatgaa   2100

attaaaaatt catttttatg aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   2220

aaaaaaaaaa aaaaaaaaaa aaaaaaa                                       2247


<210>  740
<211>  4816
<212>  DNA
<213>  Human

<400>  740
aagtgggggg gcccggctag ccattctgga agcggccggg cgcagtcttc gtagcgtacc     60

cgccggctgc gaggcgcagg gcggaggcgg agactgcgtg gcgcaggcgc gttgctgggc    120

ttctcctggg tccccagaca gctggaggag ataaacagag gaggaggagg gaggggagtg    180

cgtgtgtgag agcgcgcgag ggagtgtgag tgtgtgtgag cgcgggtgtg aggcggtgcg    240

caggggcggg cggaggcgct gtccggcccc ggccaggcgc cgggcgggga gcatgggaag    300

gggctagaac tgctcgagcc ccccagcccc ctccccggga tccgcgcccc ccttcccggg    360

agaggggccg ccccccccgg acggacatgg gctcctgaag ttgcgccgct gccggtcggg    420

ggaagagacc tgacaggtaa ttaaatgtgt attttgtgga cctgggcttg gctggaatgc    480

tcaggggtcc tgaagatcct attatagctt ccttctgttg aaccattaag aaaagatggc    540

gaaagtcaac ataactagag acctcatccg taggcagatc aaggagcggg gtgccctgag    600

ctttgagcgg cgctaccatg tcactgaccc ctttatccgg cggctgggcc tggaagcaga    660

gctgcagggt cactcaggat gtgtcaactg tctggagtgg aatgagaaag gagacttgct    720

ggcctctggt tccgatgacc agcacacgat tgtgtgggac ccgctgcacc acaagaagct    780

gctctccatg cacacgggac acaccgcaaa tatcttctct gtcaagttcc tgcctcacgc    840

tggggaccgc atcttgatca cgggggcagc cgactctaag gtgcatgtgc acgacctgac    900

agtaaaggag accatccaca tgtttggaga ccacacaaac cgggtgaagc gcatcgccac    960

agcgcccatg tggcccaaca cattctggag tgctgctgag gatgggctta tccgccagta   1020

tgaccttcga gagaacagca aacactcgga ggtgctgatt gacctgacag agtactgtgg   1080

ccagctggtg gaggccaagt gcctcactgt caacccccag gacaacaact gcctggcagt   1140

tggggccagc gggcccttcg tgaggctcta tgacatccgc atgatccata accacagaaa   1200

gagcatgaag cagagccctt cagcgggtgt gcacaccttc tgtgaccggc agaaacccct   1260

tccggacggt gcagcccagt attacgtagc aggtcacctg ccagtgaagc ttcctgacta   1320

caacaaccgt ttgagagtgc tggttgccac ctatgtgacc ttcagcccca atggcacaga   1380

gctactagtc aacatggggg gggaacaggt ctatttgttt gacttgactt acaagcagcg   1440

gccgtacacc ttcctcttgc ctagaaaatg ccactcctcg ggggtccaga atggcaagat   1500

gtccaccaac ggtgtgtcca acggtgtgtc caatggcctg caccttcata gcaatggctt   1560

ccggctgccg gagagtaggg gacatgtcag cccccaagta gagctaccac catacctgga   1620

gcgtgtgaaa cagcaagcca atgaggcttt tgcctgccag cagtggaccc aagccattca   1680

gctttacagc aaggctgtgc agagggcccc tcacaatgcc atgctttatg gaaaccgagc   1740

agcagcctac atgaagcgca agtgggatgg tgaccactat gatgccctga gggactgcct   1800

caaggccatc tccctaaacc catgccacct gaaggcacac tttcgcctgg cccgctgcct   1860

ctttgagctc aagtatgtgg ctgaagccct ggagtgcctg gacgacttca aagggaaatt   1920

tccggagcag gcccacagca gcgcttgtga tgcattgggc cgcgacatca cagctgccct   1980

cttctctaaa aatgatggtg aggagaagaa gggacctggt ggcggcgccc cagtccgcct   2040

ccgcagcacg agccgcaagg actccatctc agaggatgaa atggtgctgc gggagcgaag   2100

ctacgactat cagttccgct actgcggcca ctgcaacacc accacggata tcaaagaggc   2160

caatttcttt ggcagcaacg ctcagtatat cgtcagtggc tctgacgatg gctccttctt   2220

catctgggaa aaggagacca ccaacctggt ccgtgtgctc caaggggatg agtccattgt   2280

caactgcctg cagccacacc ccagctactg cttcctggcc accagtggca tcgatcctgt   2340

tgtgcggctc tggaaccccc gaccagagag tgaagacctc acaggccgag tcgtggaaga   2400

tatggagggt gcttcacagg ccaaccagcg gcgcatgaat gcagacccgt tggaggtgat   2460

gctgctcaac atgggctacc ggatcacggg cctgagcagt gggggtgccg gggcctctga   2520

tgatgaggac agctctgagg gccaggtgca gtgccggccc agctagaccc tccagccctg   2580

gtccccagcc cctgctactg gctggaccct ctgccctggg caggaggtca ggggattctg   2640

ttttggtttg tcttccccac cacccttttt tttcatttcc cctgttttgt ttgttagttt   2700

ggcgttaggg gtggaggttg ctacaacttg ctggctttcg gactctgggc tgattgtccc   2760

ctgactatcc ccagccctga aaaaaagagc aggaggggac acccctccat atgccccccc   2820

ccatctcctg ctttcatgtc cctggagggc tctggcctgc ctcaaaaccc cttctgcctc   2880

aggtggggag gaacaagctg aactgtcttc agggactgtc ctgcccttta gctggcagca   2940

gcaggaggag tgggattccc aattggtaag ggctcgcctt ggcctgttgc cactcttgct   3000

ccctagcctg caaggctagc tcccctgtgg tcttcaggaa aggttttgaa aaaggatggg   3060

tcccaccctc cctccagagc caccagtgtt agagcggagc ccaaaggaag gatgggagcc   3120

ctggagtggg caagaccagg ccacctgctg aggtcgctgt ggagcaccct cgctcctctc   3180

ctggctacta gctctggccc tgcacctact ctcactggcc acctctggag gctctgcctt   3240

tcccaagggc cctggcagag ggtggggcac tgcaccttac cccacccatc catgccagca   3300

cttctgcact acggccattc tcctcttggg cgctcctcag cctcactgtg acctttctgc   3360

cagagctccc agccaggcct actctgctga ggtggcgctt cctgctaagg gcccttctct   3420

gccctttctg ccctccttcc catcccacat gctgagccgc cacaaagacc aaagaagtga   3480

tggcttttct ctgtcccctg ctgctctgag gggagagggg tgggtctcct gagccactca   3540

gatgggaaag tcccttactc ggcccctccc tccccagcag ccccaagctt tacactggat   3600

gcagcgatca acccaccact caccaggcct ctcctcccct ctgcccccgg ctcttagctc   3660

cagctgctcc aggtagttgg ttcatccttc cccctctctc cctccctgct tccccttcag   3720

tgcttacttg gctccagccc tccagctgca gcccctgggg aaaagcagcc tcccttctcc   3780

tctccctcca ctccctcgct ccctccctca gcccctgtct ctgccaggtg cctcctctca   3840

gtcaggcttc agagcagccc tggagacagg agggccatgt taaaagcttt ttcacagttt   3900

taagaagaca agtggagggt gaggatagtg gtggggggtc tggcaccatc tcattgcttt   3960

aatcccagca acacaggtgg cagcttctcc cccttccttc ccaccccagt ccctcttccc   4020

acccctctct tctagcttgg taatgaagta tatttattgg tgaaggaaac agctgctgct   4080

gcttctcctg ctgctgggac ctgctcccct gtctcttctc cgtgaccttt ctctagccag   4140

ggagaaggga gagcaggagt attggggctg ggccctgggg cccaaggacc agctgggtcc   4200

cctttgcttt cttgtgttcc agccacctgc catttcctcc ctgcctccca ccctccctcc   4260

ctgccccctg tcctgcttcc caccccctgc ctgcccagcc tgggccctgc agtgtggaga   4320

gacacataag ccttactgtc ctctgggggc aggagccgag cctttttgtt gctccgctcc   4380

caggagagtg agggtgacgc aattgattaa aaccattttg ttctaggtgt ggctggtggc   4440

atttgtgggg tgcagatggg tcttggaacc aaagtgaggg cacctggtcc ctcacctctg   4500

tagctctatg acttagtaac cacacctcta ctggacagaa tgaggcctgc cttgaagggt   4560

caccgtgagc agcggccacc cagcccagca gggctgagtg cagagcccag ctctcatggc   4620

tgtgatttgt aatcatcagc tttcactctc tggctgtttt ctcatcagta aaataaggga   4680

cttggaatct tagtggtttt tcaaaccatt ttacattgtg acccaatata cacatgatta   4740

cttgtagata tgtgtgtgtg tatatatata taaaaaaaat gaacaaaagt tttacacaat   4800

aatatttacc cttgct                                                   4816


<210>  741
<211>  4087
<212>  DNA
<213>  Human

<400>  741
ggacgggggc gggcaacgcc ttagccgcag ccccggctgg ctccggagcc cggccgcctt     60

gccagggcac agtccgccga gagggccggg cggggtccgc aggccgctgc ccgccccgct    120

agggcgtcca ggagcggggc cttggctagt cagtctcccg gacgcagcca cggccgcccc    180

cgcgaggctg cggcgtctct ccagcgagcc cgcctcgggc ccgagcctgg ggtcttgtcc    240

ctgaggagcg ccgtattcta atgtaggaac tggtgagaag aaggtgactg aagcctggat    300

ttctgaggat gaaaactcac ataggacgac gtcagacaga ctcacggtga tggagctccc    360

ctctcccgag tctgaggaag tccacgagcc cagattaggg gagctcttgg gaaatccaga    420

aggtcagagc ctggggagtt ccccctctca ggacaggggc tgcaagcagg tgacagtgac    480

ccattggaag atccagacag gagagacagc tcaagtgtgc accaagtcag gaagaaacca    540

tattctgaac tcagaccttc ttctgcttca gagagagctc atagaggggg aagccaatcc    600

ttgcgatatc tgtggcaaaa ccttcacgtt taattcggac ctagttaggc atcggatttc    660

gcatgctggg gagaaacctt acacgtgcga tcagtgtggg aaaggctttg gccagagctc    720

acaccttatg gagcatcaga gaattcacac tggagagaga ctctacgtct gtaatgtgtg    780

tgggaaagac ttcattcact attcaggtct cattgagcat cagcgcgttc attcaggaga    840

aaagcccttc aaatgtgcgc agtgtgggaa ggcgttttgt cacagttcag acctgattag    900

gcaccagaga gttcacacca gagagagacc ttttgaatgc aaagagtgtg ggaaaggctt    960

cagtcagagc tccttactta ttcgccatca gaggattcac acgggagaaa ggccctatga   1020

gtgcaatgaa tgtgggaaat ccttcataag gagctcgagc ctcattcgcc attatcagat   1080

ccacacagaa gtgaaacagt atgaatgcaa agaatgtggg aaggcattcc gtcatcgctc   1140

agaccttatt gaacaccaga gaattcacac cggagagaga ccctttgaat gcaatgagtg   1200

tgggaaagcc tttattcgga gttcaaagct cattcagcat cagaggatcc atactgggga   1260

gaggccttac gtatgcaatg agtgtgggaa gcgcttcagc cagacgtcaa acttcaccca   1320

gcatcagaga attcacactg gagagaaact ctatgaatgt aacgagtgtg ggaaagcttt   1380

ctttctgagt tcatacctta ttcgacacca gaaaatccac actggagaga gagtgtatga   1440

atgtaaggaa tgtgggaaag cgtttctcca gaaagcccat ctcactgagc accagaagat   1500

ccactctggg gacaggccct tcgaatgtaa agactgtggg aaagccttca tccagagctc   1560

caagctgctt ctgcaccaga ttattcacac tggagaaaag ccctatgtgt gcagttattg   1620

tgggaaaggc tttattcaga ggtcaaactt ccttcaacac cagaaaattc atactgaaga   1680

gaagctctat gaatgtagtc agtatgggag agattttaac tcaactacaa acgttaaaaa   1740

taatcaaagg gttcaccaag agggactctc cttgagtaag gcccccatac atttgggtga   1800

gaggtctgta gataaggggg aacacacagg taacttataa aataattact ttcccgccca   1860

gtgagtgatg tttggaaatg cgtggaatta ggattcatgt ggtttctaag atttggacat   1920

gtcagaattt tgtgagtcat ggatggggct gcttttgcag tgggtgccac ctgccactgt   1980

gcagccctac tcggctcagc ccttctcctc agctgtgagc actgtcctca ggagagtcac   2040

agggcttgac acctgactct gagctggaac agtaggggca gggagaagac aggtctcaag   2100

aaaaggtttt taagaagttt catccccagt taagcagagt ccatccttga cttaaatccc   2160

ttattacagc acaactgtgt atctaatctt acgatttagg agaatgttac ctaggacatt   2220

ttgatgtgtt aagttgaaga aaggtaactc gtgtatgaac cccgagccat ttccctgttg   2280

tcctgaggag gaactccagg cctcccatcg tgtgccctaa ggcctcctgc gtcctggagc   2340

cctgcctccc actgcctgac ttcctgccac acggttaatg ctgcagcaac accgactgct   2400

tcatcttccc tgtgctccac gtggcttcct acctctctcg cctttgttct tgttgaaggg   2460

tctcttctca gctaattaac tctgaatcat ggttcaagac aagcctcagg catcatgtca   2520

atgggtgttt ccctcaagct tagttggcag cactctccac acttctgtgg ctcagtgatt   2580

actgctatta ctatatttac ttgcatatgt cagaatgatg tgatagacta tctctgtcac   2640

tatgctgttg ggttcctgag gacagtgatc atatctgatt gatttccatg tgtccactgt   2700

ctagcacagg gcaataaaaa atacacccct aaatctatgt gtaattggca tctctcttgc   2760

tttgtccttt ctatactgcc attctaaaaa ttttcagctg ttggctgttt tttttgttgt   2820

ttgttcattt tgtatcagta taatctacga ttctgttaga agtatcttct cagccctgct   2880

actgtctgct gctcctactt agaagttgca ggcaatatcc tgtgcacatc cacgccctcc   2940

tgtgtgccac cttacagctc atgcagaact gtctacttga tctggagggc attgacacct   3000

ggctcagctg gaacagtggg gacaggagga ggcaggtctc aagagaaggt ctttacttac   3060

ttgtctgtat ctttctgtct cactcgaaag gcacagtctc aatgcgctac gtaactcttc   3120

tgttgtagca gttctgaggt tgaactgagc tcttgtcatt ttccatgctc tctggctcat   3180

tgtgtcattt caaaatgtat tgatatctat aaggaatagt cctcaatgtt gggaaaacag   3240

atgagcaacc cactaccctg aagtcatcca ccgtgtagtg gggaagacgg agatcacagt   3300

agggtgagtt aagtatgtgc cctcaggtgt gaaggagcac aggtgagggg gtgcctgctg   3360

tggcacagag ctgggaaggc cttacagaag aggtgacatt tcagctgggc cagagatcag   3420

tagagagcag ctgaagaaga aaatagggtc caggagagga atctgcagaa acatggagcc   3480

atgacagatg gctttttggc taggactgtt cgaaagcagg cgaggtaaat ggacagtgga   3540

cagccgcctc gccaaactgt tagtctttac ctctgaattt catctggaca tgaaccccaa   3600

agtccagttt tgtaacgata taattttttt ctcatgaggc catattttga gttcttaaat   3660

actaccaacc ctgaacgtct caggacaaat aattcaaaaa agagatctac attttctgga   3720

aaatcagcat tactagagat gtttcaaatg tagattttac cagaccattt taatcaactt   3780

tattgagatt caattttcat atagtaaaac gcctatttaa gtgtacaagg ttttgaaaaa   3840

tctatacacc tgtgtaacca ccaccacctg tgtaaccacc accgccagaa ccaaaaacgt   3900

ttctgtcacc caaagaagtt cccttttgcc ttttcctagt taagcccact ccagccccag   3960

ataaccactt tctatcctca tagattagtg ttgcttggtt tagagcctca tacaaatgga   4020

ttcatttact atgtgttctt ttgcgtctga tgtctcactt tggcatgttt ttagactcat   4080

ccaagct                                                             4087


<210>  742
<211>  3410
<212>  DNA
<213>  Human

<400>  742
gggcgcgggc agctctgcgt ccgaagctgc tccgacgccg tcgctgggac caagatggac     60

ctcccggcgc tgctccccgc cccgactgcg cgcggagggc aacatggcgg cggccccggc    120

ccgctccgcc gagccccagc gccgctcggc gcgagccccg cgcgccgccg cctgctactg    180

gtgcggggcc ctgaagatgg cgggcccggg gcgcggcccg gggaggcctc cgggccaagc    240

ccgccgcccg ccgaggacga cagcgacggc gactctttct tggtgctgct ggaagtgccg    300

cacggcggcg ctgccgccga ggctgccgga tcacaggagg ccgagcctgg ctcccgtgtc    360

aacctggcga gccgccccga gcagggcccc agcggcccgg ccgccccccc cggccctggc    420

gtagccccgg cgggcgccgt caccatcagc agccaggacc tgctggtgcg tctcgaccgc    480

ggcgtcctcg cgctgtctgc gccgcccggc cccgcaaccg cgggcgccgc cgctccccgc    540

cgcgcgcccc aggcctccgg ccccagcacg cccggctacc gctgccccga gccgcagtgc    600

gcgctggcct tcgccaagaa gcaccagctc aaggtgcacc tgctcacgca cggcggcggt    660

cagggccggc ggcccttcaa gtgcccactg gagggctgtg gttgggcctt cacaacgtcc    720

tacaagctca agcggcacct gcagtcgcac gacaagctgc ggcccttcgg ctgtccagtg    780

ggcggctgtg gcaagaagtt cactacggtc tataacctca aggcgcacat gaagggccac    840

gagcaggaga gcctgttcaa gtgcgaggtg tgcgccgagc gcttccccac gcacgccaag    900

ctcagctccc accagcgcag ccacttcgag cccgagcgcc cttacaagtg tgactttccc    960

ggctgtgaga agacatttat cacagtgagt gccctgtttt cccataaccg agcccacttc   1020

agggaacaag agctcttttc ctgctccttt cctgggtgca gcaagcagta tgataaagcc   1080

tgtcggctga aaattcacct gcggagccat acaggtgaaa gaccatttat ttgtgactct   1140

gacagctgtg gctggacctt caccagcatg tccaaacttc taaggcacag aaggaaacat   1200

gacgatgacc ggaggtttac ctgccctgtc gagggctgtg ggaaatcatt caccagagca   1260

gagcatctga aaggccacag cataacccac ctaggcacaa agccgttcga gtgtcctgtg   1320

gaaggatgtt gcgcgaggtt ctccgctcgt agcagtctgt acattcactc taagaaacac   1380

gtgcaggatg tgggtgctcc gaaaagccgt tgcccagttt ctacctgcaa cagactcttc   1440

acctccaagc acagcatgaa ggcgcacatg gtcagacagc acagccggcg ccaagatctc   1500

ttacctcagc tagaagctcc gagttctctt actcccagca gtgaactcag cagcccaggc   1560

caaagtgagc tcactaacat ggatcttgct gcactcttct ctgacacacc tgccaatgct   1620

agtggttctg caggtgggtc ggatgaggct ctgaactccg gaatcctgac tattgacgtc   1680

acttctgtga gctcctctct gggagggaac ctccctgcta ataatagctc cctagggccg   1740

atggaacccc tggtcctggt ggcccacagt gatattcccc caagcctgga cagccctctg   1800

gttctcggga cagcagccac ggttctgcag cagggcagct tcagtgtgga tgacgtgcag   1860

actgtgagtg caggagcatt aggctgtctg gtggctctgc ccatgaagaa cttgagtgac   1920

gacccactgg ctttgacctc caatagtaac ttagcagcac atatcaccac accgacctct   1980

tcgagcaccc cccgagaaaa tgccagtgtc ccggaactgc tggctccaat caaggtggag   2040

ccggactcgc cttctcgccc aggagcagtt gggcagcagg aaggaagcca tgggctgccc   2100

cagtccacgt tgcccagtcc agcagagcag cacggtgccc aggacacaga gctcagtgca   2160

ggcactggca acttctattt ggaaagtggg ggctcagcaa gaactgatta ccgagccatt   2220

caactagcca aggaaaaaaa gcagagagga gcggggagca atgcaggagc ctcacagtct   2280

actcagagaa aaataaaaga aggcaaaatg agtcctcccc atttccatgc aagccagaac   2340

agttggttgt gtgggagcct cgtggtgccc agcggaggac ggccaggacc agctccagca   2400

gctggggtgc agtgcggggc gcagggcgtc caggtccagc tggtgcagga tgacccctcc   2460

ggcgaaggtg tcctgccctc ggcccgcggc ccagccacct tcctcccctt cctcactgtg   2520

gacctgcccg tctacgtcct ccaggaggtg ctcccctcat ctggaggccc tgctggaccg   2580

gaggccaccc agttcccagg aagcactatc aacctgcagg atctgcagtg acggcagcct   2640

cggcctgggc aggcccaagg ccacggtcta ggacacacct tccctgagac tcatgacatg   2700

agcctgggga gacctcattt ggtttccgtt cagaagacca gcgtagccct tttgagactt   2760

ttgggtacat ttatcaaaaa tgttttcctt ttgttttacc aggaatgagt tcgggctata   2820

ctctttgaaa ctgcctttgt gagcaaagtg ctttggcaag gcaagggtct ccctcagcag   2880

ggctaggtgc actacagcct ctttccccgt gtcccgttgg atctgagctg tgtagcactt   2940

gttgcattac aaagaaaaag acttctgcag gaaatagggt agagaacagg ctgtctagtc   3000

agatgcagct tgatctgtgg caaaaccaag tgtggtcttt cagcttcagt gtgttagcat   3060

cccagcacct gggatggggt ttgtgggcaa gttgattttg ccacactgta gggcccaggt   3120

ggtcccattg ccaccgtgaa gccaaattct agcccaagtc tggtagagca gtcgggcagc   3180

tagttttcgg gggaggatga tgtggtggga cagaggacct cagtggccta ttacggagcc   3240

ctcttcccag actaaattca tagccgagag ctcgggggga tggtagagtt aaaatttaaa   3300

ataattttct aaattctgta tttggatatt agtgtttaag tggtaatttg gcaacagttt   3360

ataaagtgat gttctgaata ccataaatta tgtgtaggac tgtgaaaaaa              3410


<210>  743
<211>  2322
<212>  DNA
<213>  Human

<400>  743
cccgccccct ctcttctccc tccctcctcc ttccgtgtgt ccctccccgc ccggctggag     60

gctgctccgg accgggacgc agagtctgcg gacccggcgc cgaggcggcc acccgagacg    120

cggcgcgcac gctccggcct gcgcccggcc cggccatggc ggccccccgc ccgtctcccg    180

cgatctccgt ttcggtctcg gctccggctt tttacgcccc gcagaagaag ttcggccctg    240

tggtggcccc aaagcccaaa gtgaatccct tccggcccgg ggacagcgag cctcccccgg    300

cacccggggc ccagcgcgca cagatgggcc gggtgggcga gattcccccg ccgcccccgg    360

aagactttcc cctgcctcca cctccccttg ctggggatgg cgacgatgca gagggtgctc    420

tgggaggtgc cttcccgccg ccccctcccc cgatcgagga atcatttccc cctgcgcctc    480

tggaggagga gatcttccct tccccgccgc ctcctccgga ggaggaggga gggcctgagg    540

cccccatacc gcccccacca cagcccaggg agaaggtgag cagtattgat ttggagatcg    600

actctctgtc ctcactgctg gatgacatga ccaagaatga tcctttcaaa gcccgggtgt    660

catctggata tgtgccccca ccagtggcca ctccattcag ttccaagtcc agtaccaagc    720

ctgcagccgg gggcacagca cccctgcctc cttggaagtc cccttccagc tcccagcctc    780

tgccccaggt tccggctccg gctcagagcc agacacagtt ccatgttcag ccccagcccc    840

agcccaagcc tcaggtccaa ctccatgtcc agtcccagac ccagcctgtg tctttggcta    900

acacccagcc ccgagggccc ccagcctcat ctccggctcc agcccctaag ttttctccag    960

tgactcctaa gtttactcct gtggcttcca agttcagtcc tggagcccca ggtggatctg   1020

ggtcacaacc aaatcaaaaa ttggggcacc ccgaagctct ttctgctggc acaggctccc   1080

ctcaacctcc cagcttcacc tatgcccagc agagggagaa gccccgagtg caggagaagc   1140

agcaccccgt gcccccaccg gctcagaacc aaaaccaggt gcgctcccct ggggccccag   1200

ggcccctgac tctgaaggag gtggaggagc tggagcagct gacccagcag ctaatgcagg   1260

acatggagca tcctcagagg cagaatgtgg ctgtcaacga actctgcggc cgatgccatc   1320

aacccctggc ccgggcgcag ccagccgtcc gcgctctagg gcagctgttc cacatcgcct   1380

gcttcacctg ccaccagtgt gcgcagcagc tccagggcca gcagttctac agtctggagg   1440

gggcgccgta ctgcgagggc tgttacactg acaccctgga gaagtgtaac acctgcgggg   1500

agcccatcac tgaccgcatg ctgagggcca cgggcaaggc ctatcacccg cactgcttca   1560

cctgtgtggt ctgcgcccgc cccctggagg gcacctcctt catcgtggac caggccaacc   1620

ggccccactg tgtccccgac taccacaagc agtacgcccc gaggtgctcc gtctgctctg   1680

agcccatcat gcctgagcct ggccgagatg agactgtgcg agtggtcgcc ctggacaaga   1740

acttccacat gaagtgttac aagtgtgagg actgcgggaa gcccctgtcg attgaggcag   1800

atgacaatgg ctgcttcccc ctggacggtc acgtgctctg tcggaagtgc cacactgcta   1860

gagcccagac ctgagtgagg acaggccctc ttcagaccgc agtccatgcc ccattgtgga   1920

ccacccacac tgagaccacc tgcccccacc tcagttattg ttttgatgtc tagcccctcc   1980

catttccaac ccctccctag catcccaggt gccctgaccc aggacccaac atggtctagg   2040

gatgcaggat ccccgccctg gggtctggtc ctcgcccatc ctgcagggat tgcccaccgt   2100

cttccagaca ccccacctga ggggggcacc aggtttagtg ctgctgcttt cactgctgca   2160

cccgcgccct cggccggccc cccgagcagc ctttgtactc tgcttgcgga gggctgggag   2220

accctccagg acattcccac cctcccccat gctgccaagt tgtagctata gctacaaata   2280

aaaaaaaacc ttgttttcca gaaaaaaaaa aaaaaaaaaa aa                      2322


<210>  744
<211>  4656
<212>  DNA
<213>  Human

<400>  744
gggcgggtgg gaggagagcg cgaaggggcg aggcccgttt gcaggggccg ctcggcccgg     60

ggaagcccgc gccccgctca gccttgcagc cccgcgcccg gagcatctcc ctggaggaac    120

ggagacaaag gaggattcat gtccaaaggg ctcccagaga ccaggacgga cgcagccatg    180

tcagagctgg tgcctgagcc caggcctaag ccagcggtgc ccatgaagcc catgagcatc    240

aactccaacc tgctgggcta catcggcatc gacaccatca tcgagcagat gcgcaagaag    300

accatgaaga ccggtttcga cttcaacatc atggtcgttg gccagagtgg actgggcaaa    360

tcaacgctgg tcaacacgct cttcaaatcc caagtgagcc gcaaggcctc cagctggaac    420

cgggaggaga agatccccaa gacagtggag atcaaagcta tcgggcatgt gatagaggaa    480

ggcggtgtca aaatgaagct gaccgtcatc gacaccccag gctttggaga ccaaatcaac    540

aatgaaaact gctgggagcc cattgagaag tacatcaatg agcagtacga gaagttcctg    600

aaggaggagg tcaacatcgc caggaagaaa cgcatccctg acactcgtgt ccactgctgc    660

ctttacttca tctctcccac aggacactcc ttgcgacctc tggatcttga gttcatgaaa    720

cacctcagca aggttgtgaa catcatccct gtcattgcta aggctgacac catgaccctg    780

gaggagaagt ctgaattcaa gcaaagggtt cgcaaggagc ttgaagtaaa tggcattgaa    840

ttctaccccc agaaggaatt tgatgaggat ttggaggata agacggagaa tgacaaaatc    900

aggcaggaga gcatgccttt tgctgtggtg ggaagtgaca aggagtacca agtgaatggc    960

aagagggtcc tcggccgaaa aactccatgg gggatcatcg aagtggaaaa cctcaaccac   1020

tgtgagtttg ccctgcttcg agactttgtc atcaggaccc acctccagga cctcaaggaa   1080

gtgacacaca acatccacta tgagacttac agggccaagc ggctcaatga caatggaggc   1140

ctccctccgg tgagcgtgga cacagaggaa agccacgaca gtaacccatg acgaccactt   1200

ctctgtgtca tcacacatac ccacttcaca cacacacatc ccaaatacca ccaccaacca   1260

ccttcttcct ctcaactctg tcccacaggc ctgtctggta tttgtggagc atcttgtctg   1320

tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgac agagagagag cgagagagcc   1380

tgtgtgtgtg catgcagggg tgaggtattt tcactgccct ccctggagag tcccttgtaa   1440

gtttggctcc tccatgcctg tccattatct gtctcctttc cttgtgtccc aaaacaaagc   1500

tgtttgcctc actcaggaga tctgggggag gtttcattta aaagtgctgg gagcaggtga   1560

gccacaggca actcttctct cggaacctgc acacaaactg gggctataga gattctccaa   1620

ggacagatgg cagtggagct agacctgagt agggggcagg gagttcagga caaccctcct   1680

gtaagttggg ggtggtctgg gggtaaggct ggggcttcct gggaaaagga aggccatgag   1740

aaggcagaga agtaggccag agctgggttc ttgcagaaag catcagtgcc tacaaatgga   1800

gctccaccct tcagtctgtg tcgtgttcag tgtcacaaag ctaccacctg tcaccagagc   1860

ctactgctgc tctccactca actggcctct gctgccaggc cactgcctgt ctctgcttcc   1920

gactttgtct tctttctccc tttccctcct tccctcatac attgctttct ctccctctcc   1980

tgcgtgtctc tgacatctct cacttccttt tagatgaatc tactttaggt tcattcctat   2040

atttagcatt tatgcccagt ctacttccag aaatgacttt agactgcctt tcacataaaa   2100

tcacaaaact acaggacagt acaaacagat tgccagagaa atctgggtca aagaaaggaa   2160

taggaaagaa agtttctgta gtcaagcacc tgaacaggcc ctgagctcac aggcagccaa   2220

tgtaaagagg gaaacacagt gagttatgca gttcccagtg tccagttaaa ggaagcacac   2280

atgctagtca tgtgagacaa ccttttattg ggacatcagg ttctagaact aattctaaag   2340

aagtatcaga aacaatatac ataatttgtc tttcttagta atttggcttc aaagacaaat   2400

ttttgaccac acctccgttt tctccgtcag acttctctcc cttctaagca ggcttctctg   2460

ttgctccatt tgcttcatac atacttgacc tctcttttct attccccatc acttttgtgc   2520

tgaagctaat catatttatg tctgtctttc tctacttttc cctaattccc tctcctcctg   2580

actcctgtag acattcccaa tgatacccac cgtcatacat ttaggctttt cttgcctttc   2640

cctgaagccc tgtatttatt aatgcatata tttcccctgc ttgttgtaca agtaagttac   2700

tcttttcctt taatctgtaa gattcatgaa attcggggcc agggaaacag tttagcctta   2760

gggaagggaa aacactaagt gaaactgttt acaataacct catacaacct tctgtcccat   2820

ctcctggttc agcctaggtg tttcactggt cctctatgaa tcccagcact tataatccca   2880

gtcttttatc actcaggtgc taggaaaaaa aacatagact caagacccaa gattcaatgg   2940

accaggagaa aggggggcgg tgatcaggtc accagtgacc ccaacctatg ctctcggtct   3000

ttcctggagg ctgccaaccc agccctcatc ctcccttgct cacaaagtta cagggtaggc   3060

acctgtcagg acagaacagc agcagcgcta cagcccagag gttatacatt tcaacagaac   3120

agggatcctt ggctactgta gaagcagtcc tgtatggaga ccttggacca gcaggggaag   3180

atctatgggc atgggaggtg ggcgttggaa aggctgagta ggaatggtgc ctggcacccc   3240

tgaaccatga tctgagcctc cctggagaag gtattttata tgtctgctgc cagctgctgg   3300

tctccacacc ctcaaccgtt ctcaaccccc ctgcagggag aaggcctcct gggcactgtc   3360

cttccacctg tgccagccac cccctgcccc actgctgaat gaaggccatt tcaagcgctg   3420

cttctcactc cattcctctc agctgttatt gctgcagggc caagcccttt ttagtgctgt   3480

gctcgtccag ctcaccacca cagcccctct cagccctcag taggtgggag gggccagctg   3540

cctctttagg ccagttgcat cctccattta tccaaaccac tcctctcctc ccagtggagt   3600

ggggttctgc cagtacagcc ctactgcatc atctgcgtca gccggtccta gcccatctgc   3660

agggtgaaag aactcatcaa gagctccttc tgcccttgta agcccatccc agctacttgt   3720

aaccatctct aagggcaatg gcattgctcc ctacccattc atctgcatga gctactcttg   3780

gcttccttaa agggtcaaga aagcaatttt tctgcttact agattcattg agatcagctg   3840

tgtgagcccc aaagtgggac aagggtgtct ccttcattac ttaaagatat tcatgagggt   3900

gggtcactac agatgttggg gagcaagggc taggatcact ttttaaaaaa tcaccacttg   3960

tggctgtccc agagtgcggt tgtacatcct ccccacctca taacgcagcc actgaggaag   4020

agtggttttc ctaagaagac attgctggag ttgactttct tctgtccaaa caaacaaaca   4080

aaaactaaac acacacacaa acccccagaa acccacaata tgtacacgct aaggaaaaac   4140

tagcaccctt ctgtccactc agcaataaga gggatctctt cccacctacc ctacctactc   4200

ctacccccaa cccccttccc cattaatgtg agtaatgaat tagcctgacc acaggtggtc   4260

actgtaggct aatggaaaat acccaaggga gggcaaagcc ccccatcaga tgcatgaatg   4320

tttgcgaatg ttgactgcca ctgccccaca cactgtgtct ttatagaatt cccctttgcc   4380

caccctcttc ctgtctccac ctggacacaa cttgctcaaa ggctggtgac ttgtgggcca   4440

ttcatctaca accaagtcct gatggagcaa gaggcccacg cctaggggat gcaagaacaa   4500

cccgtttctt aaatgttacc agtcccagcc aatcttacgg tgacattaca gttaaatttc   4560

ccaattgaaa acaagcaaac agacactcaa actggtcctg taattgttgc tagactttat   4620

gtgttgtaca actaaacatt gctgtttgaa cagtaa                             4656


<210>  745
<211>  2090
<212>  DNA
<213>  Human

<400>  745
ggagcgggcg gcggcggcgg cggcgcggag gggccgctca ccccgcagcc cggcctcggc     60

ctccgccgct tgtcgtcgcg ccccgcccgc gagcccgccc cgcacgtccc ccgccggcgg    120

ccaccatgag cacaggcctg cggtacaaga gcaagctggc gaccccagag gacaagcagg    180

acattgacaa gcagtacgtg ggcttcgcca cactgcccaa ccaggtgcac cgcaagtcgg    240

tgaagaaagg ctttgacttc acactcatgg tggctggtga gtcaggcctg gggaagtcca    300

cactggtcca cagcctcttc ctgacagact tgtacaagga ccggaagctg ctcagtgctg    360

aggagcgcat cagccagacg gtagagattc taaaacacac ggtggacatt gaggagaagg    420

gagtcaagct gaagctcacc atcgtggaca cgccgggatt cggggacgct gtcaacaaca    480

ccgagtgctg gaagcccatc accgactatg tggaccagca gtttgagcag tacttccgtg    540

atgagagcgg cctcaaccga aagaacatcc aagacaaccg agtgcactgc tgcctatact    600

tcatctcccc cttcgggcat gggctgcggc cagtggatgt gggtttcatg aaggcattgc    660

atgagaaggt caacatcgtg cctctcatcg ccaaagctga ctgtcttgtc cccagtgaga    720

tccggaagct gaaggagcgg atccgggagg agattgacaa gtttgggatc catgtatacc    780

agttccctga gtgtgactcg gacgaggatg aggacttcaa gcagcaggac cgggaactga    840

aggagagcgc gcccttcgcc gttataggca gcaacacggt ggtggaggcc aaggggcagc    900

gggtccgggg ccgactgtac ccctggggga tcgtggaggt ggagaaccag gcgcattgcg    960

acttcgtgaa gctgcgcaac atgctcatcc gcacgcatat gcacgacctc aaggacgtga   1020

cgtgcgacgt gcactacgag aactaccgcg cgcactgcat ccagcagatg accagcaaac   1080

tgacccagga cagccgcatg gagagcccca tcccgatcct gccgctgccc accccggacg   1140

ccgagactga gaagcttatc aggatgaagg atgaggaact gaggcgcatg caggagatgc   1200

tgcagaggat gaagcagcag atgcaggacc agtgacgctc gccgcggaca caccgtccgt   1260

ctccgggacg ccctcgcacc cctggacacc agaccggact gttcccgacc cggagacgcg   1320

gggccacagc ccccagctga ccctaattta ttctcagcac caccccctcc caggtcattg   1380

tgtctgtttc cgaggggcct ggaccgtagc ccccgcccag ctggccctct ctgaccttgg   1440

gggatcagga gcgaagttgg gcgggacttc agagatccgc ctcccttgcc cttcccccgc   1500

ccccggacgg tcacagcacc caaaccgcag gccctgctct ggcaggcagg caaagctagg   1560

cagaagagga ttcccaggat cctgggtctg ttccctgccc cagtgctgca gaacggactt   1620

gggagccctc ctttgcctgc tcccgcgggt cacccagcga gtgctgagac cccattttct   1680

gtcgaggcgg gccgagtctt cccttatccc cagacgccta gcgggcaggg ttgggctgaa   1740

tcaaatggga gccctccaga cataaggagg ccagaggctg caaggagcgg ggtcgtgacc   1800

gcttacaccc cttctccaca gcccggcccg acctggaggg cccccggggc actgggcggt   1860

gagccacctc ctggcaactc tcggtgccgt cccctgccct cgctcgaggc ctcttctccc   1920

cagcaccgct gtggtgtgcc gggatcctga gcctaggcct cccgatgttc ccacccgcat   1980

gatcccttcc cgccacacga tgctccgttt tcttccgttg tgaatgccgc gtcctgtcct   2040

ggtgacagga gaacaatgtt ggtgaacgtc gcaaaaaaaa aaaaaaaaaa              2090


<210>  746
<211>  2172
<212>  DNA
<213>  Human

<400>  746
aatcccttca accttctgcg cgcttccgcc ttcatgctag caacgcccgc agtgacgcgc     60

aggccccgcc ccctcccgcg cgcctcccgg aagtggccgg tccagagctg tggggtggcc    120

tccgcgcggt ctctggcgga gtcggggaat cggatcaagg cgagaggatc cggcagggaa    180

ggagcttcgg ggccgggggt tgggccgcac atttacgtgc gcgaagcgga gtggaccggg    240

agctggtgac gatggcgggg ccgcagcccc tggcgctgca actggaacag ttgttgaacc    300

cgcgaccaag cgaggcggac cctgaagcgg accccgagga agccactgct gccagggtga    360

ttgacaggtt tgatgaaggg gaagatgggg aaggtgattt cctagtagtg ggtagcatta    420

gaaaactggc atcagcctcc ctcttggaca cggacaaaag gtattgcggc aaaaccacct    480

ctagaaaagc atggaatgaa gaccattggg agcagactct gccaggatcg tctgatgagg    540

aaatatctga tgaggaaggg tctggagatg aagattcaga gggactgggt ctggaggaat    600

atgatgagga cgacctgggt gctgctgagg aacaggagtg tggtgatcac agggagagca    660

agaagagcag aagccactct gcaaaaacac cgggcttcag tgtccagagt atcagtgact    720

ttgagaaatt taccaaggga atggatgacc ttgggagcag tgaggaggag gaagacgaag    780

agagtggcat ggaagaaggg gatgacgcgg aagactccca aggcgagagt gaggaagaca    840

gggctggaga tagaaacagt gaggatgatg gtgtggtgat gaccttctct agtgtcaaag    900

tttctgagga agtggagaaa ggaagagccg tgaagaacca gatagcactg tgggaccagc    960

tcttggaagg aaggatcaaa ctacaaaaag ctctgttgac caccaaccag cttcctcaac   1020

cagatgtttt cccattgttc aaggacaaag gtggcccaga attttccagt gccctgaaaa   1080

atagtcacaa ggcacttaaa gcattgttga ggtcattggt aggtcttcag gaagagttgc   1140

ttttccagta cccagacact agatatctag tagatgggac aaagcccaat gcgggaagtg   1200

aggagatttc tagtgaagat gatgagctgg tagaagagaa gaagcagcaa cgaagaaggg   1260

tccctgcaaa gaggaagctg gagatggagg actatcccag cttcatggca aagcgctttg   1320

ccgactttac agtctacagg aaccgcacac ttcagaaatg gcacgataag accaaactgg   1380

cttctggaaa actggggaag ggttttggtg cctttgaacg ctcaatcttg actcagatcg   1440

accatattct gatggacaaa gagagattac ttcgaaggac acagaccaag cgctctgtct   1500

atcgagttct tggcaaacct gagccagcag ctcagcctgt cccagagagt ttgccagggg   1560

aaccggagat ccttcctcaa gcccctgcta atgctcatct gaaggacttg gatgaagaaa   1620

tctttgatga tgatgacttt taccaccagc tccttcgaga actcatagaa cggaagacca   1680

gctccttgga tcccaacgat caggtggcca tgggaaggca gtggcttgca atccagaagt   1740

tacgaagcaa aatccacaaa aaagtagata ggaaagccag caaaggcagg aaacttcggt   1800

ttcatgtcct tagcaagcta ctgagtttca tggcacctat tgaccatact acaatgaatg   1860

atgatgccag gacagaactg taccgctctc tttttggcca gctccaccct cccgacgaag   1920

gccacgggga ttgacatcgc ccacctccga cacccagtgg gcgccttggc tggtgcggct   1980

gctggtccag atggaggaaa ccagtgactt tatggggctg agctagtagg gaagcccctg   2040

gaaagatgct gcgttccgaa cctgtgccta atacacgcaa gggcgctgtc ccgcccaacc   2100

ccgcctttaa acgccacaaa taaagagcat tgttaccgcc aaaaaaaaaa aaaaaaaaaa   2160

aaaaaaaaaa aa                                                       2172


<210>  747
<211>  1317
<212>  DNA
<213>  Human

<400>  747
cggagtgaca gccccacggg ccacgcagca agcagaagat ccccgggagt caccctcaac     60

cctctggggc cacgtgggcc catgaatacc agcctgtctg cgagttagac gccagtcctg    120

gtggcccggg aagcccagat ccgcatcagc ggttctgcac cccacaccag catgtgctca    180

ctgcctgtgc cccgggagcc cctgcgtcgc gtggctgtga ctgggggcac gcatggcaac    240

gagatgtcgg gcgtctacct ggcccggcac tggctgcatg cccccgcaga gctgcagaga    300

gccagcttct ccgctgtgcc tgtgctggcc aacccggcag ccacatccgg ctgccgccgc    360

tacgtggacc atgacctcaa ccgcaccttc accagcagct tcctcaattc caggcccacc    420

ccggacgacc catatgaggt gacaagagcc cgagagctga accagctgct ggggcccaag    480

gcctcgggcc aggcctttga ctttgtcctt gacctgcaca acaccacggc caacatgggc    540

acctgcttaa tcgcgaagtc ctcccacgaa gtctttgcca tgcacctgtg ccgccatctg    600

cagctgcagt accccgagct gtcctgccag gtcttcctgt accagcggtc tggggaggag    660

agctacaacc tggactctgt ggccaaaaat ggactgggtc tggagctggg cccccagcca    720

cagggtgtgc tgcgggctga cattttctca aggatgagga ccctggtggc cacagttctg    780

gacttcatcg aactcttcaa ccagggtacg gcctttcctg cctttgagat ggaagcctat    840

agacccgtgg gcgtcgtgga cttcccccgc accgaggccg ggcacctggc aggcactgtg    900

catcctcagc tgcaggaccg agacttccag ccactgcagc ctggtgctcc catcttccag    960

atgttcagtg gggaggacct gctctatgag ggagagtcca cggtgtaccc cgtgttcatt   1020

aacgaggctg cctactatga gaagggcgtt gcctttgtcc agactgagaa gttcacattc   1080

accgtgcctg ccatgcccgc gctgacccct gccccgagcc cagcttccta acccaagaca   1140

cacctcccca acctcagtct tcccatctga acgatgggtc ctgaggcaca gctctgagca   1200

cagaggtccc ttctgccacc taccatgcac catgttcctt gccaggcctc cccaacccct   1260

ggcctcaatt tccctttcta taaaatggaa gatgtccaga aaaaaaaaaa aaaaaaa      1317


<210>  748
<211>  6772
<212>  DNA
<213>  Human

<400>  748
agctgcgggc ggctccagct gcccccagat gtgggctggg cggctcgcgg ggaactttcg     60

cgccggctgc gagtgcgggg ccccggctgc agtccggctg ccatggatcc gccggcggga    120

gccgctcgcc gcctgctctg ccccgcgctg ctgctgctgc tgctgctgct gccgccgccg    180

ctcctgccgc cgccgccgcc gcccgcgaac gccaggctcg ccgccgccgc cgacccccca    240

ggcgggcccc tggggcacgg agcggagcgc atcctggcgg tgcccgtgcg cactgacgcc    300

cagggccgct tggtgtccca cgtggtgtcg gcagctacgt ccagagcagg ggtacgagcc    360

cgcagggccg ccccggtccg gaccccgagc ttccccggag gcaacgagga ggagcctggc    420

agtcacctct tctacaatgt cacggtcttt ggccgagacc tgcacctgcg gctgcggccc    480

aacgcccgcc tcgtggcgcc cggggccact atggagtggc agggcgagaa gggcaccacc    540

cgcgtggagc ccctgctcgg gagctgtctc tacgtcggag acgtggccgg cctagccgaa    600

gcctcctctg tggcgctcag caactgcgat gggctggctg gtctgatccg gatggaggag    660

gaggagttct tcatcgaacc cttggagaag gggctggcgg cgcaggaggc tgagcaaggc    720

cgtgtgcatg tggtgtatcg ccggccaccc acgtcccctc ctctcggggg gccacaggcc    780

ctggacacag gggcctccct ggacagcctg gacagcctca gccgcgccct gggcgtccta    840

gaggagcacg ccaacagctc gaggcggagg gcacgcaggc atgctgcgga cgatgactac    900

aacatcgagg tcctgctggg cgtggatgac tctgtggtgc agttccacgg gaaggagcac    960

gtacagaagt acctgctgac actcatgaac attgtcaatg aaatctacca tgacgagtcc   1020

ttgggtgccc acatcaacgt ggtcctggtg cggatcatcc tcctgagcta tggaaagtcc   1080

atgagcctca tcgagatcgg gaacccctct cagagcctgg agaatgtctg ccgctgggcc   1140

tacctccagc agaagccaga cacgggccac gatgaatacc acgatcacgc catcttcctc   1200

acacggcagg actttgggcc ttccggcatg caaggctatg ctcctgtcac cggcatgtgc   1260

catccggtcc gcagctgcac cctgaaccat gaggacggct tctcctcagc gtttgtggtg   1320

gcccatgaga ctggccacgt gctgggcatg gagcacgacg ggcagggcaa ccgctgtggc   1380

gacgaggtgc ggctgggcag catcatggcg cccctggtgc aggccgcctt ccaccgcttc   1440

cactggtccc gctgcagcca gcaggagctg agccgctacc tgcactccta tgactgcctg   1500

ctggatgacc ccttcgccca cgactggccg gcgctgcccc agctcccggg actgcactac   1560

tccatgaacg agcaatgccg ctttgacttc ggcctgggct acatgatgtg cacggcgttc   1620

cggacctttg acccctgcaa gcagctgtgg tgcagccatc ctgacaaccc ctacttttgc   1680

aagaccaaga aggggccccc cttggacggg actatgtgtg cacctggcaa gcattgtttt   1740

aaaggacact gcatctggct gacacctgac atcctcaaac gggacggcag ctggggcgct   1800

tggagtccgt ttggctcctg ctcacgtacc tgtggcacgg gcgtgaagtt caggacccgc   1860

cagtgtgaca acccacaccc ggccaacggg ggccgcacct gctcgggcct tgcctacgac   1920

ttccagctct gcagccgcca ggactgcccc gactccctgg ctgacttccg cgaggagcag   1980

tgccgccagt gggacctgta cttcgagcac ggcgacgccc agcaccactg gctgccccac   2040

gagcaccggg atgccaagga gagatgccac ctgtactgcg agtccaggga gaccggggag   2100

gtggtgtcca tgaagcgcat ggtgcatgac gggacgcgct gctcctacaa ggacgccttc   2160

agcctctgtg tgcgcgggga ctgcaggaag gtgggctgtg acggtgtgat cggctccagc   2220

aagcaggaag acaagtgtgg cgtgtgcgga ggggacaaca gccactgcaa agtggtcaag   2280

ggcacgttca cacggtcacc caagaagcat ggttacatca agatgtttga gatccctgca   2340

ggagccagac acctgctcat tcaggaggta gacgccacca gccaccatct ggccgtcaag   2400

aacctggaga caggcaagtt catcttaaat gaagagaatg acgtggatgc cagttccaaa   2460

accttcattg ccatgggcgt ggagtgggag tacagagacg aggacggccg ggagacgctg   2520

cagaccatgg gccccctcca cggcaccatc accgttctgg tcatcccggt gggagacacc   2580

cgggtctcac tgacgtacaa atacatgatc catgaggact cactgaatgt cgacgacaac   2640

aacgtcctgg aagaggactc tgtggtctac gagtgggccc tgaagaagtg gtctccgtgc   2700

tccaagccct gtggcggagg gtcccagttc accaagtatg gctgccgccg gaggctggac   2760

cacaagatgg tacaccgtgg cttctgtgcc gccctctcga agcccaaagc catccgcaga   2820

gcgtgcaacc cacaggaatg ctcccagcca gtgtgggtca caggcgaatg ggagccatgt   2880

agccagacct gtgggcggac aggcatgcag gtgcgctccg tgcgctgcat tcagccgcta   2940

cacgacaaca ccacccgctc cgtgcacgcc aagcactgca atgacgcccg gcccgagagc   3000

cgccgggcct gcagccgcga gctctgccct ggtcgttggc gagccgggcc ctggtcccag   3060

tgctcagtaa cctgtggcaa cggcacccag gagcggccag tgctctgccg caccgcggac   3120

gacagcttcg gcatctgcca ggaggagcgt cctgagacag cgaggacctg caggcttggc   3180

ccctgtcccc gaaacatctc agatccctcc aagaagagct acgtagttca gtggctgtcc   3240

cgcccggacc ccgactcgcc catccggaag atctcgtcaa agggccactg ccaaggcgac   3300

aagtcaatat tctgtaggat ggaagtcttg tcccgctatt gctccatccc aggctacaac   3360

aagctgtgct gcaagtcctg taacctgtac aacaacctca ccaacgtgga gggcaggata   3420

gagccaccgc ctgggaagca caacgacatt gacgtgttca tgcctaccct cccagtgccc   3480

actgtagcca tggaggtgcg gccatcacca agcacccccc tggaggtccc tctcaatgcc   3540

tccagcacca atgccacaga ggatcaccca gaaaccaatg ccgtagatga accctacaaa   3600

atccatggcc tggaagatga agtccagcca cccaacctaa tccctcgacg accgagcccc   3660

tatgaaaaga ccagaaacca aagaatccaa gagctcattg atgagatgcg gaagaaagag   3720

atgctcggaa agttctaata aaatggaaag atagcatccc tagcattttt ttcttgctta   3780

tagagatatt ccatgggata gcaaatcctg tgtcatggag atgaagtcaa aattcctgat   3840

tccaaaaggt tttgagaaaa caaagagggg gaatgacgta agaaagatag gcatgagcat   3900

gtggtaacta ggttagcacg tgtgcttccc agcccaggag cgaccaaata ctgtggtggc   3960

gtcaggtgtg cagtggagag gaatatagag gctgtatggc ctccctcagt gagggcaggg   4020

caagagggat cactctgaga gaacaaaaat aggccccaag ttgctaagca gtgattggga   4080

accttccttt ccttggcgga gatgcatgac attccctacc gatccccaga cacagcctgt   4140

gggactctta ggagaaatgg tgatttactg aataactgac ccgttgccga gatgagtaca   4200

atgaagtgga ggtgatgaac tcaaatcgtc ttccagggcc aggcggctga ccggggtgag   4260

cgtagtggcc cgctggggac catggccgcc ctgacagcca cacccacctg gagctgactt   4320

ggttctggct gttgctgcca ctgtgaaatc tgtatctctc tccatctctg ctctactatc   4380

cccggccttg ccagacagtg ttctttttcg gaagaagtct agatttttgc atgaaaaaaa   4440

ctcaatcttt aaaggtcgac tcagaacatt ttaaggaggc ctccacttgg tctgatgcag   4500

tcttgctaat taagaactaa aggccttctg accttcttgg tgctcatgct gtacggcatc   4560

tgaatgtctc gaccgagtct gagccgtgca gctgtcctcc acctgcgaaa gtaatgagaa   4620

tcctatcacg ggacataagg ataggtctaa acagggtcca tgccaagaaa acagtggggt   4680

gctctcccag gcctctcccc tgtccactaa ccctggcctt gccggctgcc ttccaggctc   4740

tgggggaaga gctcctgcat tcttccctgg ccaccttggc tccagggctc cccagagagc   4800

ctcttccctc cccaagtacc tgagaaagat gagagaggca cgtgctctgc tgggaaggtc   4860

cagtgagcgg ttcaagggcc tggaatctcc ctacggccaa gtctaagggt tctgggattc   4920

tgggctttgt gggctttgct tgcttgctgg gaatgggctt tccctgtccc gccctgcccc   4980

acctcgcctc tgtctctcag aagctccaga acccagcagt gacctgcaaa atgtggcctc   5040

tgatgggggc ttagggtggg agatggggag agcctacatt gtcttttgct ccttgaaaac   5100

tttaatagct cctattttcc agagaatggt gctttgtgag caacatgcga gtaagagaga   5160

aataggagga agggggagta ggggcggatg ggagaagagt ggctcatttt tacctctcac   5220

tgccttgaca ttttgtgaac gtgaagctta aactttctgg gcttacaaga cccaggggca   5280

cgtcagctcc ttagatgggc tcagcctgac acataattct taaacctttc ctgtttaaga   5340

aacttctaga ggctgtgtac tctcaccaat cctcttcgag aatttgttca tgtgtatttc   5400

cccattatat ggatgaggct caggataaca gcatagtggc taccttctac tgagttttga   5460

ggtgctaata agtatgtttg tctgaggctg cacatgtggg tggctctgtg tgtatgatcc   5520

aagggacaaa atgacgatgt aggaaccagc aagaacggaa tctgggctga tgcttcagtc   5580

tccacctggg tgatggctag cctcccgccc tccaccaccg catcccacac gtgctgcgca   5640

ctgtccccgt gtctcctgga gaaccaaact ggagaaaacc tttctgagta tctctcatag   5700

taccccttcc ttaagaagat gtggtttaga gcatgtgtgc aatcctgcct ctgtaattag   5760

gaaacggagc ccgaggcttt ccattgttgg ttgaacccag gacagctggt gctattcaca   5820

ggctgaagaa ctgggcagtt cttacttggg tctgtcctag gatgtggagg aagttcagga   5880

ctaacgctag gcagagagta tgactcggtt tacccagcct aggggcctct ggatgggaac   5940

actccattcc aagatctcag cagagcaggg cttcctggct tgaggctgga agcctttggg   6000

aagaggccca gctgggacat tccctgggca cctgtcttcc gctgaaggga gcaaggtgcc   6060

ctctgggact gacagccatg accctctgtg ccatcctcaa tccttgagcc atatatcaag   6120

agtcctctag agccggatgg tcctcaaaag tctgtccaag gaatgccaac gttcaccggg   6180

ctctgagaaa cgacgcaaat ctctgagctg gggaccactt ggagaaccgg cttagtaaca   6240

gtcctgatct tcgcaagcca gcttcttctg catctgaggg gctcctggcg cccagaggag   6300

gcagacagat gtcttctagc tgagtttcta accgcatgat gagactcaga ccttccgctg   6360

cactagaaaa tctgcaacag tgtccctgag tcacttctcc ttagtgggca gactcgtgtt   6420

agatttgtgg aacccagctc tctgatttac tccttttgga aaacccatgg aatttcatgt   6480

ataaggcttt catttgtatt ttaaggtttt tctgtttgtt ttgagtatat acatggtgct   6540

caatagcaac atcttagcag atgaagcagt ttatgattcc actccctcct gtatgacagg   6600

tagccactat actgaatcaa ggtgctgaac tcaaatcaca aaattctggc ttaccgatac   6660

aacaaccaat acatctttgt tctgtaatgt aaaatttgac tccttacttt tataacttat   6720

taaagttaaa atgtctgtgt ttttgcaaat catgaaaaaa aaaaaaaaaa aa           6772


<210>  749
<211>  3223
<212>  DNA
<213>  Human

<400>  749
gccgacgtca gcgcgccggg gcggggctgg cggcaggaga cgccgcgttg agagcttggg     60

ctcctccgtg agccgccggc gcgcttcgct gcctggcggc ctttccccga gccgagcccg    120

cttcccgagg ccgccagtcg tcgcctgccc gcgcctgcgc agcgtcccgg gccgagaggg    180

ccacggcggc ggccatggcg caccgctgtt tgcggctgtg gggccggggc ggctgctggc    240

cccgcggcct acagcagctc ctcgtgcctg gcggcgtggg cccgggcgag cagccctgcc    300

tccggacgct ttaccgattt gttacaactc aagcaagggc cagcagaaat tctcttttga    360

cagatataat tgctgcttat caaagattct gttctcgacc cccaaaagga tttgaaaaat    420

actttcctaa tggaaaaaat ggaaaaaaag ctagtgaacc taaagaagtt atgggagaga    480

aaaaagaatc aaagccagct gctaccacac gctcttctgg aggaggaggt ggtggcggtg    540

gaaaacgagg tggcaagaaa gatgattctc actggtggtc caggtttcag aagggtgaca    600

ttccatggga cgacaaggat ttcaggatgt tcttcctctg gactgctctg ttctggggtg    660

gagtcatgtt ttacttgctg ctcaagagat ccgggagaga aatcacttgg aaggactttg    720

tcaataacta tctttcaaaa ggagtagtag acagattgga agtcgtcaac aagcgttttg    780

ttcgagtgac ctttacacca ggaaaaactc ctgttgatgg gcaatacgtt tggtttaata    840

ttggcagtgt ggacaccttt gaacggaatc tggaaacttt acagcaggaa ttgggcatag    900

aaggagaaaa tcgggtgcct gttgtctaca ttgctgaaag tgatggctct tttctgctga    960

gcatgctgcc tacggtgctc atcatcgcct tcttgctcta caccatcaga agagggcctg   1020

ctggcattgg ccggacaggc cgagggatgg gcggactctt cagtgtcgga gaaaccactg   1080

ccaaggtctt aaaggatgaa attgatgtga agttcaaaga tgtggctggc tgtgaggagg   1140

ccaagctaga gatcatggaa tttgtgaatt tcttgaaaaa cccaaagcag tatcaagacc   1200

taggagcaaa aatcccaaag ggtgccattc tcactggtcc tccaggcact gggaagacgc   1260

tgctagctaa ggccacagcc ggagaagcca atgtcccctt catcaccgtt agtggatctg   1320

agtttttgga gatgttcgtt ggtgtgggcc ctgctagagt ccgagactta tttgcccttg   1380

ctcggaagaa tgccccttgc atcctcttca tcgatgaaat cgatgcggtg ggaaggaaga   1440

gaggaagagg caactttgga gggcagagtg agcaggagaa cacactcaac cagctgctgg   1500

tggagatgga tggttttaat acaacaacaa atgtcgtcat tttggccggc accaatcgac   1560

cagatatcct ggaccccgcg ctgcttaggc cggggcgttt cgacaggcag atctttattg   1620

gaccaccaga cataaaagga agagcttcta ttttcaaagt tcatctccga ccgctaaaac   1680

tggacagtac cctggagaag gataaattgg caagaaaact ggcatcttta actccagggt   1740

tttcaggtgc tgatgttgct aatgtctgta atgaagctgc gttgattgct gcaaggcatc   1800

tgtcagattc cataaatcag aaacactttg aacaggcaat tgaacgagtg attggtggct   1860

tagagaagaa aacgcaggtt ctgcagcctg aggagaagaa gactgtggca taccacgaag   1920

caggccatgc ggttgccggc tggtatctgg agcacgcaga cccgctttta aaggtatcca   1980

tcatcccacg tggcaaagga ctaggttatg ctcagtattt accaaaagaa caatacctct   2040

ataccaaaga gcagctcttg gataggatgt gtatgacttt aggtggtcga gtctctgaag   2100

aaatcttctt tggaagaatt acaactggtg ctcaagatga cttgagaaaa gtaactcaga   2160

gtgcatatgc ccaaattgtt cagtttggca tgaatgaaaa ggttgggcaa atctcctttg   2220

acctcccacg tcagggggac atggtattgg agaaacctta cagtgaagcc actgcaagat   2280

tgatagatga tgaagtacga atacttatta atgatgctta taaaagaaca gtagctcttc   2340

tcacagaaaa gaaagctgac gtggagaagg ttgctcttct gttgttagaa aaagaagtat   2400

tagataagaa tgatatggtt gaacttttgg gccccagacc atttgcggaa aaatctacct   2460

atgaagaatt tgtggaaggc actggcagct tggatgagga cacctcactt ccagaaggcc   2520

ttaaggactg gaacaaggag cgggaaaagg agaaagagga gcccccgggt gagaaagttg   2580

ccaactagag gcccagaggg aggccatctc agtctgtcca ctgtggtttc agctggtgca   2640

ttatttcagc tgtggctttc agaagaatgg gaatgctgcg ctgattttag ccagccactg   2700

gcccagctga aatgatgggg aaaggagtcc ttagtccttt cagcctcaga ggtcacagtg   2760

ggtggcaggt gactttccgg aggccttgag ggaaatgcac actgtcccat agcctcattg   2820

ggctcccaga cgtgctggaa aggttgagcc cagagtggcc gaggctggac cctgtggcac   2880

caagtggggt cggctgaccg tgtggcaggg atcgttgcac tggactcttg gcgtgtggga   2940

agggatgctt tctctttgtc gcccactctt cattcctgtt tctcctcagt tcccctgtgc   3000

agatgggctg tgaaattaaa ttggagtctt gataagaaca ttttaatttg acttaatatt   3060

ttaaagattg aatccagatc acttgttgct gtcttaatgg aatggttttc tacaggagct   3120

gtaacatact taaaaatatg aatgtattat gtaaatatgg cttctttaca taaaaaataa   3180

aatgtcaaca ctgtactttt ctgaacacaa aaaaaaaaaa aaa                     3223


<210>  750
<211>  3621
<212>  DNA
<213>  Human

<400>  750
tcataataga attctcatga gatctggttg tttgaaagtg tgtagcacct ccaccttctc     60

tctctctctc cctctccctc tcctgccagc caagtgaaga catgcttact tccccttcac    120

cttccttcat gatgttacca ttggaatgac atactgcatc ctatagttat accatccact    180

ctgaaatcaa tgtgaattta acttcagttc catacagaaa cttcttttcc acaggtaaga    240

aacggttgaa ctggatgcaa tttttatcac agcttgtgta agactgcctc tgtccctcct    300

ctcacatgcc attggttaac cagcagacag tgtgctcagg ggcgttgcca gctcattgct    360

cttatagcct gtgagggagg aagaaacatt tgctaaccag gccagtgaca gaaatggatt    420

cgaaatacca gtgtgtgaag ctgaatgatg gtcacttcat gcctgtcctg ggatttggca    480

cctatgcgcc tgcagaggtt cctaaaagta aagctctaga ggccgtcaaa ttggcaatag    540

aagccgggtt ccaccatatt gattctgcac atgtttacaa taatgaggag caggttggac    600

tggccatccg aagcaagatt gcagatggca gtgtgaagag agaagacata ttctacactt    660

caaagctttg gagcaattcc catcgaccag agttggtccg accagccttg gaaaggtcac    720

tgaaaaatct tcaattggac tatgttgacc tctatcttat tcattttcca gtgtctgtaa    780

agccaggtga ggaagtgatc ccaaaagatg aaaatggaaa aatactattt gacacagtgg    840

atctctgtgc cacatgggag gccatggaga agtgtaaaga tgcaggattg gccaagtcca    900

tcggggtgtc caacttcaac cacaggctgc tggagatgat cctcaacaag ccagggctca    960

agtacaagcc tgtctgcaac caggtggaat gtcatcctta cttcaaccag agaaaactgc   1020

tggatttctg caagtcaaaa gacattgttc tggttgccta tagtgctctg ggatcccatc   1080

gagaagaacc atgggtggac ccgaactccc cggtgctctt ggaggaccca gtcctttgtg   1140

ccttggcaaa aaagcacaag cgaaccccag ccctgattgc cctgcgctac cagctgcagc   1200

gtggggttgt ggtcctggcc aagagctaca atgagcagcg catcagacag aacgtgcagg   1260

tgtttgaatt ccagttgact tcagaggaga tgaaagccat agatggccta aacagaaatg   1320

tgcgatattt gacccttgat atttttgctg gcccccctaa ttatccattt tctgatgaat   1380

attaacatgg agggcattgc atgaggtctg ccagaaggcc ctgcgtgtgg atggtgacac   1440

agaggatggc tctatgctgg tgactggaca catcgcctct ggttaaatct ctcctgcttg   1500

gcgacttcag taagctacag ctaagcccat cggccggaaa agaaagacaa taattttgtt   1560

tttcattttg aaaaaattaa atgctctctc ctaaagattc ttcacctact ttggtctcca   1620

taacttctat gttttctctc cttctgacac actagtgccc ccaaattgtg atttgcctat   1680

acgtttaggg ccggggttgg aagatgttaa caaccattta agattcattt ctgcagtggg   1740

agtgggtgga gtttcaccct ctgggaaagg ggcaggtgac aggtatttat cagtcagtgc   1800

ctctctagct cttgtaggaa gaagcacacg caggatggag tctagaggat gagcgatatt   1860

gactagcaat tcatgggctc cctccagcag tgcgagggtc agagtttctg gagccttggg   1920

aggaggcatc cctgtgaggg ggggttaggg agatgggagg gcaccaggaa aagtgattag   1980

aagtcaggta tgggaaggct aaataggaca gagtcgagta catctctgct tggaaaaaca   2040

tatcaacacc cttttttttg atcattatat cttgttcata aaagaaaact ttccacattg   2100

ttttaacaaa ccccacagct gagagtcagg cctgaatctt tgatgtgtgc ccattcacaa   2160

cgttgaccct attggtttgt ggtggggcag gacatcgaag atatcattga ctcatcacat   2220

tcccctgaat agctcatatt tagaaaatat tcttagattg taaaaatgta ctgttcattt   2280

gttatatgca atcttttaaa tgttttatac tttaaacaag gcatagttac aagtataaaa   2340

cataaatatc ccaaagccat tatgcatggc actcaagatt aaaatgggaa ataatacatc   2400

taataaatca aatgttccaa gacttcaaat gtcttttgga aacaggctat gtaaaacagc   2460

acactggttt caaactttgg taaattttaa gaagaactct tacaaaggca tttaattctt   2520

atacataatt ttcaggggaa ctaatcaaat cagctaatca tgaagacatg attttcgttt   2580

tagaaaacac ttttgaaaac ttgggataat ctcatgtctt aatgatcaaa gcattatgag   2640

aaggacagtg gttttttacc tgggcacact ttctaacaca tttactctcc actattcgta   2700

ctctggtagc catgttaacc ccatcagaga ttccttctca agccatgtct cagagctgat   2760

aggcatccca gcaagttttg cagctcacaa tttttctgta aattacttat tctataaaat   2820

tggaagaggc cataaacttt ggagggccct agaccaattt tttggattat ttctggtcta   2880

ctctcattcc gttgatgatc ttagatattc tctgcattaa atatcacctc taggctgaga   2940

aatccaccaa aaaatatttc tagctcagcg ttttcctcca aatcttcaat ggaagatcat   3000

aatgtgaact ctgcatctcc atgttaaagt ttaatggaca ttcacactta gcatgtctca   3060

aagaaatctc atgtaaacca tggccatcct gttctacctt aactttctga gtctatggaa   3120

tgataatttc acatctcata aacttgactg atgtaagtgt caagaaaaga ttgacatttt   3180

gttaaaactt cgtagccaag tgtgtaacgc ttaagcagac tttcatattt caaatctcta   3240

tagcacgtgt aactcttttt tcaagatgtg aaataatcat taggtcagtc atttgtaaat   3300

agtacggctg ctgtgggctt tttccagttc ttcaccatcc atttttataa aactcttatt   3360

gttaaaaaaa aaaagttact cagaatttca taaagccaaa cacctgattt caggaacact   3420

tgagatgtaa gaaaatttta tagggacctc caatcactaa ttttcctatt ttttctctca   3480

aagaaatgct gaagggagga attcaggttg aatgaaagga aatagtaact tacagccata   3540

tagagttata aagacttctt gtaaatgtga acatatggta aaatataaaa acatgtattt   3600

ttgaaaaaaa aaaaaaaaaa a                                             3621


<210>  751
<211>  3631
<212>  DNA
<213>  Human

<400>  751
ctcttccgcg ccggcagggg cagcagcggg agcagcgcgg ggcggagcgg cgccagcagc     60

caggagcggc ccggcccggc ccggcgcggc ggcggcggcg gcagcggcag cggcagcgac    120

gccagagccc gtgggcgccg ttcgcgaggc cgccgcagag gcccggccgc agcgcaggga    180

agcctggggg ccagaggtcg ccgctgccgc catgccgctg ctcttcctcg agcgcttccc    240

ctggcccagc ctccgcacct acacgggcct cagcggcctg gccctgctgg gcaccatcat    300

cagcgcctac cgcgcgctca gccagcccga ggccggcccc ggcgagccgg accagctaac    360

ggcctcgctg cagcctgagc cgccggcgcc cgcccggccg agcgccgggg gaccccgggc    420

ccgcgatgtg gcccagtacc tgctctcaga cagcctcttc gtgtgggttc tagtaaatac    480

cgcttgctgt gttttgatgt tggtggctaa gctcatccag tgtattgtgt ttggccctct    540

tcgagtgagt gagagacagc atctcaaaga caaattttgg aattttattt tctacaagtt    600

cattttcatc tttggtgtgc tgaatgtcca gacagtggaa gaggtggtca tgtggtgcct    660

ctggtttgcc ggacttgtct ttctgcacct gatggttcag ctctgcaagg atcgatttga    720

atatctttcc ttctcgccca ccacgccgat gagcagccac ggtcgagtcc tgtccctgtt    780

ggttgccatg ctgctttcct gctgtggact ggcggccgtc tgctccatca ccggctacac    840

ccacggaatg cacaccttgg ctttcatggc tgcagagtct cttcttgtga cagtgaggac    900

tgctcatgtg attttacgat acgtaattca cctctgggac ctcaaccacg aagggacgtg    960

ggaaggaaag gggacgtatg tctattacac agactttgtc atggagctca ctctcctgtc   1020

cctggacctc atgcaccata ttcacatgtt gttatttggc aacatctggt tatccatggc   1080

cagcctggtc atctttatgc agctgcgtta cctgtttcat gaggtgcaac gtcgaattcg   1140

tcggcacaag aactatctac gtgtggttgg aaacatggag gccaggtttg cagttgcaac   1200

tccagaggag ctggctgtca acaatgacga ctgtgccatc tgttgggact ccatgcaggc   1260

tgcgcggaaa ctgccctgtg gacatctttt ccacaactcc tgtcttcgtt cctggctaga   1320

acaagacacc tcctgtccaa catgcagaat gtctcttaat attgccgaca ataatcgtgt   1380

cagggaagaa catcaaggag agaacttgga tgagaatttg gttcctgtag cagcagccga   1440

agggagacct cgcttaaacc aacacaatca cttcttccat ttcgatgggt ctcggattgc   1500

gagctggctg ccgagttttt cggttgaagt gatgcacacc accaacattc ttggcattac   1560

gcaggccagc aactcccagc tcaatgcaat ggctcatcag attcaagaga tgtttcccca   1620

ggttccatac catctggtac tgcaggacct ccagctgaca cgctcagttg aaataacaac   1680

agacaatatt ttagaaggac ggattcaagt accttttcct acacagcggt cagatagcat   1740

cagacctgca ttgaacagtc ctgtggaaag gccaagcagt gaccaggaag agggagaaac   1800

ttctgctcag accgagcgtg tgccactgga cctcagtcct cgcctggagg agacgctgga   1860

cttcggcgag gtggaagtgg agcccagtga ggtggaagac ttcgaggctc gtgggagccg   1920

cttctccaag tctgctgatg agagacagcg catgctggtg cagcgtaagg acgaactcct   1980

ccagcaagct cgcaaacgtt tcttgaacaa aagttctgaa gatgatgcgg cctcagagag   2040

cttcctcccc tcggaaggtg cgtcctctga ccccgtgacc ctgcgtcgaa ggatgctggc   2100

tgccgccgcg gaacggaggc ttcagaagca gcagacctcc tagcgctccc ttgccttcct   2160

cagctgcctc ctgcgccctg tgcccgactg actggaggag gcctgtccca attctgcccg   2220

ctccatggaa aagcgggctt gactgcattg ccgctgtata aagcatgtgg tcttatagtg   2280

tttggacagc tgataaattt aatccttctt tgtaatactt tctatgtgac atttctcttc   2340

cccttagaaa cactgcaaat tttaactgta ggtatgatct cttctggtgt tgactggact   2400

gcttggggtg ggggacgatc aggaggaagt gagcagtcgc ctgcctgcag caggcagctt   2460

ctactcctgc ctcatgcgta cgtcccacaa atgcaggtgt cctgagcacc acacccagtg   2520

ggaagagtgt gggggaggcg cacagtgtga gcccgccccc acgtcgtggg gtaacatctg   2580

ttatcaaact gctgtcgttg ttgtggaagc atgtagactg tgccagaggc cagacccacg   2640

ggctcatgca cccctgagcc agcagggcat cttggaaaag gaactcttgg ttcgatacct   2700

ggagcagagg aggggaaagt ccagggctat agggtgtgat gaagtcaccc ctttctgtcc   2760

cactacatct gggactgact ttccgagcct ccagtccaaa gccggcttga tttccgtgaa   2820

ctctggtgct cctgcatctc atgagtgtgc cccatgggtc ccctcccctc tcagcatttc   2880

cttgtcccgt ctggacctgg ggagtggtta ggcagcaagc tttggtttat ggttttcatt   2940

cattggtgaa gtaaattagg cagtgctaaa gcctgtgggt ttggtccttg aacaagatgt   3000

gggccttgca agatgggaga gtaaaccttg aagggcttta ttaaagaaat aaaaaagaac   3060

ttttgtatct tttatcctgg gagcactgcg ttttcctagc tgtgttattc ctggtttaat   3120

tcagcagaga aggtaaggtg tgaacctacc tgccttggag agggcccagg tcccaaatct   3180

cttcaaattc ttcacatgtt taactttaag gatttgaacc atgaagtcat aggttacaga   3240

cctcagtttt atgccccatt ggattacttt tttttttttt tttttttttt ttttttttac   3300

tctttgaaag ctttgttttg tggtagtcct tttgggaaga atccagtatt atccacaatt   3360

attggcaaag tttaaatgta ttttacataa cggaaagttt ttagaatgtt gaaaagtaat   3420

tgaaaaaggt gataggtaaa tttttaggca aagataattt atttcaataa atctttcaaa   3480

agccttacct tgaaatgctg ttagtaaatt tctgtgattt ttttttttaa tttgttttgc   3540

tgagagcata gctatttgtt tttattgtaa aacaataata ataataaaaa gcaaactcta   3600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a                                  3631


<210>  752
<211>  3241
<212>  DNA
<213>  Human

<400>  752
ggaagacaga gcagtgcatg gttatggata ctggacaagg atatttggaa aggttgacga     60

tgtgtcacac tgtgtaaggg aatcgcatgg agatgggcat tccgaactgt taatggggac    120

atgggactcc agttgtctct gatcacttgt gtggattttc ctggcgtaga acgacagaag    180

ccgctagtaa gtcgccaaga cctacagcag gaattctgca ccaaagggca taaaatcttg    240

ttattttaat ttgcatctgg gagaatgtct gagcaaggag acctgaatca ggcaatagca    300

gaggaaggag ggactgagca ggagacggcc actccagaga acggcattgt taaatcagaa    360

agtctggatg aagaggagaa actggaactg cagaggcggc tggaggctca gaatcaagaa    420

agaagaaaat ccaagtcagg agcaggaaaa ggtaaactga ctcgcagcct tgctgtctgt    480

gaggaatctt ctgccagacc aggaggtgaa agtcttcagg atcaggaatc aattcattta    540

cagctttcca gtttttccag cctgcaagag gaggataaat ctaggaaaga tgactctgaa    600

agagaaaaag aaaaggataa aaacaaagat aaaacctctg aaaaacccaa gatcagaatg    660

ttatcaaaag attgcagcca agaatacacg gattctacag gcatagactt acacgagttt    720

ctgattaaca cattaaagaa taattccagg gacaggatga tacttttgaa aatggagcag    780

gaaattattg atttcattgc tgacaacaat aatcattata aaaagttccc tcagatgtca    840

tcgtatcaga ggatgcttgt ccatcgagtg gcagcttatt ttggattgga tcacaatgtg    900

gatcaaacag gaaaatctgt tatcatcaac aagaccagca gcaccagaat accagagcaa    960

aggttttgtg aacatttaaa agatgaaaaa ggtgaagaat cccagaagcg gtttatcttg   1020

aagcgagata actctagtat tgataaagaa gacaatcagc aaaacagaat gcatccattt   1080

agagatgaca gacgaagtaa atcaattgaa gagagagaag aggaatatca gagagtgagg   1140

gagagaatat ttgcacacga ttcagtttgc tcccaggaaa gcctttttgt ggaaaacagt   1200

aggctcttgg aagacagtaa catatgcaat gagacctata agaaaagaca gctctttcgg   1260

ggcaacagag atggctcagg gagaacatct gggagtcgac agagcagctc agaaaatgaa   1320

ctcaagtggt ctgaccacca aagggcctgg agcagcacag actccgacag ttccaaccgc   1380

aatctaaagc ccgccatgac caagacggcg agttttgggg gcatcacggt gctgaccagg   1440

ggtgacagca cttccagtac taggagtacc gggaagctgt ccaaagcagg ttccgagtct   1500

tccagcagtg caggctcctc aggatcgctg tcccgcaccc atccacctct ccagagcaca   1560

cccctagtct caggtgtggc agctggctct ccaggctgtg tgccttatcc agagaatgga   1620

atagggggcc aggttgctcc cagcagcacc agctacatcc tccttccact tgaagctgca   1680

acaggcatcc cgcctggaag catccttctt aatccacaca caggccagcc ctttgtgaat   1740

cccgatggaa ctcctgcaat atacaaccca cccaccagtc agcagcccct gcgaagcgcc   1800

atggtggggc agtcccaaca gcagccacca cagcagcagc cctccccgca gccccaacag   1860

caggtccagc caccgcagcc acagatggca ggccctctgg tcactcagag agatgatgtg   1920

gcaacacagt ttggccagat gaccctgagc cggcagtcct cgggggagac tcctgaaccc   1980

ccatcaggtc ctgtctaccc atcctccctt atgccacagc cggcccagca gcccagctat   2040

gtaatcgcct ctacaggcca gcagcttcct acaggaggat tctcaggctc tggccctccc   2100

atctcccagc aggtcctcca gccccctccc tcaccacagg gatttgtgca acagcctccg   2160

cctgcacaga tgcctgtata ttattaccca tctggtcagt accctacctc aaccacgcaa   2220

cagtaccggc ccatggcccc ggttcagtac aacgctcaga ggagtcaaca gatgccacag   2280

gcagcacagc aagcaggtta ccagccagtc ttgtctggtc aacagggatt ccaaggccta   2340

ataggagtgc agcagccacc tcagagtcag aacgtgataa ataaccaaca aggaactccg   2400

gtgcaaagcg tgatggtttc ctacccaaca atgtcttctt atcaggtgcc aatgacccag   2460

ggttctcaag gactgcccca gcagtcatac caacagccaa tcatgctacc taaccaggca   2520

ggtcaagggt cactcccagc cactggaatg cctgtttact gtaatgtcac accgcccacc   2580

cctcagaaca accttaggct gattggccca cactgcccct ccagcactgt cccagtgatg   2640

tcagctagct gcagaacaaa ctgtgcaagt atgagcaatg ctggttggca ggtcaaattc   2700

tgagagctct ggctgtggta catttcttca gatatttctc atggcctttg atggaagagg   2760

aacaaggtgg gaaaactggc tgaggactta agtattcact caacactcaa atgattgctg   2820

ctggtattct gtaaaaaata aacaaagact aatatacacg ttagctggtt aatggtgcat   2880

atttctgtca tgtctgctag gtatgccttt atagcttagc tagtgacatg aattcatcaa   2940

ggtaagattt tctcctacca ctgaatacca ctgtgtagat tataatatcc ctaatttgga   3000

ttagttttgt actttgtgtt gagtttgtga tgctaaaagt atttaaaaat tatatactaa   3060

atcacattgt accaaagctg taatggaaaa gcaaagaaga attgatgaat tgaaggaata   3120

atttatatac attatagagt tttctttttt aatggatata tactgtattg tagtgtttaa   3180

tcaaaataaa actatttgac cttatggagg aaggtcatgt ttttaccacc agtttggttc   3240

a                                                                   3241


<210>  753
<211>  4056
<212>  DNA
<213>  Human

<400>  753
ggtctcgggt tgcgcgctgg gcctggaggg agggggcggc ccccgcaccg gtccgagttg     60

cggccgcgtg gactgcgacc cgcgccgcgc cgcaccgcgc cgcgccctgg gaacgccgct    120

ccccgcgcgc caacggaccc ggggaagccc ttctggggtc cgaggccgcg ctgcggggcc    180

gcccacgctg cgctccagga gccagagcct gcagggtggg tgtcgggaca tgctgatctt    240

ccctcaagac agctggcggg cgctctggtc atggaggact gcaatgtgca ctcggccgcc    300

agcatcctgg cctcggtgaa ggagcaggag gcccgcttcg agaggctgac acgggcactg    360

gagcaggagc ggcgccatgt tgccctacag ctggagcgtg cccagcagcc tggcatggtc    420

agtggtggca tgggcagtgg gcagcccctg ccaatggcct ggcaacagct ggtcctccag    480

gagcagagcc caggcagcca ggcctcactg gccacgatgc cggaggcacc tgatgtgctg    540

gaggagaccg tgacggtgga ggaggacccc ggcacaccca cttcccatgt gtctattgtc    600

acatccgaag atggcacaac ccggcgcacc gagaccaagg tcaccaagac tgtcaagacg    660

gtgaccactc ggacagtacg ccaggtgccc gtgggcccag atggactccc cctgctggat    720

ggcggccccc cactaggccc ttttgcagat ggtgccctgg accggcattt cctgctgcgt    780

ggtggtggcc cagtggccac actctctcga gcctacctca gcagtggggg tggctttccc    840

gaaggccccg agccccggga cagccccagc tatggcagcc tgtcccgagg gctgggcatg    900

cggcccccac gtgctggccc ccttggccca ggccctggtg atggctgctt cacactgcct    960

ggccaccggg aagccttccc ggtgggtcct gagcctgggc caccaggtgg ccgctccctg   1020

cccgagcgct tccaggcaga gccgtatggc ttggaggatg acacgcgcag cctggccgct   1080

gatgacgagg gtggccctga gctggagcct gactatggca cggccacaag gaggaggcct   1140

gagtgtgggc ggggccttca taccagggcc tacgaggaca cagcagatga tggcggcgag   1200

ctggcggacg agcggcctgc gttcccaatg gtgacggcgc ccctggccca gcctgaacgg   1260

ggcagcatgg gcagcctgga ccggctggtg cggcgctcgc cctcagtgga tagcgcccgc   1320

aaggagccgc gctggcggga ccctgagctg cctgaggtgc tggccatgct gcggcacccc   1380

gtggaccccg tgaaggccaa tgcggccgcc tacctgcagc atctgtgctt tgagaacgag   1440

ggtgtcaagc ggcgtgtacg gcagttgcgg gggctgccgc tgcttgtggc actgctggac   1500

cacccgcggg ctgaggtgcg gcgccgggcc tgtggggcac tgcgcaacct ctcctatggc   1560

cgcgacactg acaacaaggc cgccatccgg gactgcggtg gtgtgcctgc cctggtgcgc   1620

ctgctgaggg ctgcccggga caacgaggtc cgtgagcttg tcactggcac cctgtggaac   1680

ctgtcatcct atgagcccct gaagatggtc atcattgacc atggcctgca gacgctgacc   1740

cacgaggtga tcgtgcccca ctcaggatgg gagcgtgagc ccaacgagga ctccaagcca   1800

cgggacgccg agtggacaac tgtcttcaag aacacgtcgg gctgcctgag gaatgtgagc   1860

tccgatggtg ctgaggcccg gcggcgactc cgggagtgtg aagggctggt ggacgcgctc   1920

ctgcatgccc tgcagtcggc tgtgggccgg aaggacactg acaacaagtc ggtggagaac   1980

tgcgtgtgca tcatgcggaa cctgtcctac cacgtgcaca aggaggtgcc cggggccgac   2040

aggtaccagg aggccgagcc cgggcccctg ggcagtgctg taggctccca gcgccggagg   2100

cgggatgatg ccagctgctt tggaggcaag aaggccaaag aggagtggtt ccaccaagga   2160

aagaaggatg gtgagatgga ccggaacttt gacacgctag acctgcccaa gcgaactgag   2220

gccgccaaag gctttgagct gctgtaccag cccgaggtgg tacgtctcta cctctccctc   2280

ctcacggaga gccggaactt caacaccctg gaggctgccg ccggcgctct gcagaacctc   2340

agtgccggca actggatgtg ggccacgtac atccgcgcca cagtgcgcaa agagcgcggg   2400

ctgccggtgc ttgtggaact gctgcagtct gagaccgaca aggtggtgcg cgccgtcgcc   2460

atcgctctgc gcaacctctc gctggaccgg cgcaacaaag acctcatcgg gagctacgcc   2520

atggctgagc ttgtgcggaa tgtgcgcaat gcacaggctc cgccgcgacc gggggcctgc   2580

ctggaggaag acaccgtggt ggcggtgctc aacaccatcc acgaaatcgt gtccgacagc   2640

ctggataacg cgcgctcgct cctgcaggca cgcggggtgc cagcgttggt ggctctcgtg   2700

gcctccagcc aatcggtacg cgaagcgaag gcggcgtcac acgtgctgca gacagtgtgg   2760

agctacaagg agctgcgtgg taccttgcag aaagatggtt ggaccaaggc gcgcttccag   2820

tcagctgctg ctactgccaa ggggcctaag ggagcactga gtcctggggg cttcgatgac   2880

agcacgctgc cactggtgga caagagcctt gagggcgaga aaactggcag ccgggatgtg   2940

atccccatgg atgcgctggg cccagacgga tactccacgg tggaccggag ggagcggagg   3000

ccacggggcg ccagctctgc aggagaggcc tctgagaagg aacccttgaa actcgacccc   3060

agcaggaagg cccctccccc cgggcccagc aggcccgcgg tcaggctggt ggacgccgta   3120

ggggacgcta agcctcagcc cgttgattcc tgggtctagc ttgcatgcct gggcccaggc   3180

ccagcctctt gttcttaggg cttggatcgt ggaagaaggg ccaccctgag cagatcgtgc   3240

cgtggagctt ggagccccct ggcggcaggg gttggcagcg cctcgcccca gccaagcctg   3300

actttgggga caccctcctg cccccccacc ccactccccc catcctacct aactccctag   3360

gcctgagtta gctgtttact gacatggtgc tgtgtgtgag cgagtgacag aaggcccgag   3420

gaggccgact gggctgctgg ggcagggccc agggaggtgg cagggaaggg tgcctggctg   3480

ggctttgggg ctggtgggat aggagggtgc ccctgggaac acagtgcccc agtggtgcgg   3540

gccaggtctg gcgccagggg caggcagcta ggcagggagg gggctgggaa agaacttgga   3600

cttctaaagg cggagggtct ccctgggcac cctgcaggca ggcagaccac ggtgtggggg   3660

gtgccccaca aggcccagcc ctgggcaagg aagctttgga agcagcaagg tgggggtcag   3720

gctacaggtg ccccacctcc ccagagccct gcagtcacgt gaggcccctg tgcagtagag   3780

agcctttctc cagcccatgc tggctggggc cggggctgcc gcatctgcct ggagcctggg   3840

cagcacctcc gggactgacc ttcggcagtg gctgggggac tgctttcagt gcctgctgtt   3900

cgtgactcag aaacagaaga aaaacactga gaaaaagcat taaaaataag ccaaaataag   3960

actattggta aacacctaaa tttttgtaag aaaatttaaa aattaaagca gcaaaggaac   4020

tttttgcttt ctgccaaaaa aaaaaaaaaa aaaaaa                             4056


<210>  754
<211>  2347
<212>  DNA
<213>  Human

<400>  754
gttccccgcg tgccaccagg aagctcgggc cggccaagag cgtagactct tgagaggagt     60

gagacaggtg cgcgccagcc ggccttcggg gctttatggg aactgggccg tgcggcggtc    120

ccgccctcgt gcgcaggcgc agaaccgttg tgaccagagc ggttgcgggc tgagcggttt    180

cgagccggcg tcggggagcg gcggtaccgg gcggctgcgg ggctggctcg acccagcttg    240

aggtctcggc gtccgcgtcc tgcggtgccc tgggatccgc cgacatgaat cccatcgtag    300

tggtccacgg cggcggagcc ggtcccatct ccaaggatcg gaaggagcga gtgcaccagg    360

gcatggtcag agccgccacc gtgggctacg gcatcctccg ggagggcggg agcgccgtgg    420

atgccgtaga gggagctgtc gtcgccctgg aagacgatcc cgagttcaac gcaggttgtg    480

ggtctgtctt gaacacaaat ggtgaggttg aaatggatgc tagtatcatg gatggaaaag    540

acctgtctgc aggagcagtg tccgcagtcc agtgtatagc aaatcccatt aaacttgctc    600

ggcttgtcat ggaaaagaca cctcattgct ttctgactga ccaaggcgca gcgcagtttg    660

cagcagctat gggggttcca gagattcctg gagaaaaact ggtgacagag agaaacaaaa    720

agcgcctgga aaaagagaag catgaaaaag gtgctcagaa aacagattgt caaaaaaact    780

tgggaaccgt gggtgctgtt gccttggact gcaaagggaa tgtagcctac gcaacctcca    840

caggcggtat cgttaataaa atggtcggcc gcgttgggga ctcaccgtgt ctaggagctg    900

gaggttatgc cgacaatgac atcggagccg tctcaaccac agggcatggg gaaagcatcc    960

tgaaggtgaa cctggctaga ctcaccctgt tccacataga acaaggaaag acggtagaag   1020

aggctgcgga cctatcgttg ggttatatga agtcaagggt taaaggttta ggtggcctca   1080

tcgtggttag caaaacagga gactgggtgg caaagtggac ctccacctcc atgccctggg   1140

cagccgccaa ggacggcaag ctgcacttcg gaattgatcc tgacgatact actatcaccg   1200

accttcccta agccgctgga agattgtatt ccagatgcta gcttagaggt caagtacagt   1260

ctcctcatga gacatagcct aatcaattag atctagaatt ggaaaaattg tcccgtctgt   1320

cacttgtttt gttgccttaa taagcatctg aatgtttggt tgtggggcgg gttctgaagc   1380

gatgagagaa atgcccgtat taggaggatt acttgagccc aggaggtcaa agctgaggtg   1440

agccatgatt actccactgc actccagcct gggcaacaga gccaggccct gtatcaaaaa   1500

aaaaaaaaaa aagaaaaggg aaaaaagaaa gaaagcagca gcatgatcct gacatgacag   1560

atgtgggaga cccacagcct gcagacactg tgggctggaa ggtgggaagg gaggggccgg   1620

tggaggtgga gctgtttgaa agtgacacag cagcagtaga agcagtggtg ggcgaagccc   1680

aggtgaccct cagaacgttg cacaagaaca tcagggaaaa gaaccagaat cctttaagga   1740

aaatgttctt catgtatgag agactaaagt gatttttcta agaaagttca gcccttctct   1800

gacttacctg gacatttcta gatacttcca aaggaccctc tgggaatcca tagcttccta   1860

atctggagat gggaggtcat aagggagacg ctgtggggtt ccttgaagtt tcttgggttc   1920

acagaggagc cccctcactt ggtgttctcc cgtgagccag cctccacctg ccaaagacac   1980

tctggtcctc gtatagtgag taatggggct cagggcctct ccaacaacag agaggagctg   2040

atgctgtagg gctgaccccg tgacttcctg agtcctcacc ctgtccagtg ctttgagatt   2100

cttcccacct ccccatcctc accagccgga tcgggcgctg tgcagtgtgg tcagcatggt   2160

gaagaaagtc atttcctcgg tgggcagtat tcctctttat ctctcattac actggaaatg   2220

ttatttctgc tgtatcatcc gtgctcaacg ttttagtctg tcaggctcac cttctctctg   2280

gaaagaattt gcttaacttg acattccatg tgccgctaat aaaatatatt ttgaaagaat   2340

aaaaaaa                                                             2347


<210>  755
<211>  815
<212>  DNA
<213>  Human

<400>  755
agagaaccta gcggttacgc caacgcgcgc gtgcgccctt gcgcgtttct ctcttcccac     60

tcgggtttga cctacagccg cccgggagaa gatggctgcc ccagcagtgt ccgggctctc    120

ccggcaggtg cgatgcttca gtacctctgt ggtcagacca tttgccaagc ttgtgaggcc    180

tcctgttcag gtatacggta ttgaaggtcg ctatgccaca gctctttatt ctgctgcatc    240

aaaacagaat aagctggagc aagtagaaaa ggagttgttg agagtagcac aaatcctgaa    300

ggaacccaaa gtggctgctt ctgttttgaa tccctatgtg aagcgttcca ttaaagtgaa    360

aagcctaaat gacatcacag caaaagagag gttctctccc ctcactacca atctgatcaa    420

tttgcttgct gaaaatggtc gattaagcaa tacccaagga gtcgtttctg ccttttctac    480

catgatgagt gtccatcgcg gagaggtacc ttgcacagtg acctctgcat ctcctttaga    540

agaagccaca ctctctgaat taaaaactgt cctcaagagc ttcctaagtc aaggccaagt    600

attgaaattg gaggctaaga ctgatccgtc aatcttgggt ggaatgattg tgcgcattgg    660

cgagaaatat gttgacatgt ctgtcaagac caagattcag aagctgggca gggctatgcg    720

ggagattgtc taaaagtgtt ggttttctgc catcagtgaa aattcttaaa cttggagcaa    780

caataaaaag cttccagaac agatcaaaaa aaaaa                               815


<210>  756
<211>  2859
<212>  DNA
<213>  Human

<400>  756
gcggagagga gggacgggct gggagagggc ccggactagg ggcggcgggc accgcaggag     60

ctccgcgcgg ctgcagcgcg ggcgggagcg gggacgcgat gtcgccgccg ccgcctcctt    120

gcgggccggg gctgcgcctc cggggctgag ccgccgccag agccgacagc cgagcagccg    180

ctgggcgctc ccgcggcgca ggaggatggg ctgcggcggg agccgggcgg atgccatcga    240

gccccgctac tacgagagct ggacccggga gacagaatcc acctggctca cctacaccga    300

ctcggacgcg ccgcccagcg ccgccgcccc ggacagcggc cccgaagcgg gcggcctgca    360

ctcgggcatg ctggaagatg gactgccctc caatggtgtg ccccgatcta cagccccagg    420

tggaataccc aacccagaga agaagacgaa ctgtgagacc cagtgcccaa atccccagag    480

cctcagctca ggccctctga cccagaaaca gaatggcctt cagaccacag aggctaaaag    540

agatgctaag agaatgcctg caaaagaagt caccattaat gtaacagata gcatccaaca    600

gatggacaga agtcgaagaa tcacaaagaa ctgtgtcaac tagcagagag tccaagcaga    660

agggcagatg gacttcttca gtgtccttca cggcactgga tcccatcaaa gaaccttgaa    720

gaagtggctg ccccttgctg gacctgaatt ctactgagtc cctggcaaga ctgtcttacc    780

tggcagcaaa ctgctgcctg atttgttggg accttctgag ccttctactt atcatgtaaa    840

tgtattggca cagtgcttac atatgttaat aaactgcaaa tgtgcagttc agtttgtctc    900

tttgcaactc ctgtaatacg gtctggtgta aaagtagtga gttaaagcta caggtcagtt    960

tatgaaacag aaaagtagga atgcattttc tgggtgaaag agtcacacct tagtgctata   1020

actctcctgc ccatgatagt gtattctgtt tcaggcaagc ttattctttc cttctttcat   1080

tttaaatatt gtcattacaa atcttaccag gttcacttaa aagctggctt tcatccaact   1140

ctaaacccac atattgaaaa aatcaaggta caggaaaact ccttgttatc cttgtttcct   1200

tagcttggta tgagacagat cggatccagt ttcccatgca ccaacccact gcccatggca   1260

tgtctttggg aggtgtctgt gaagcagtca tacctgctcc tcatctgcct ggaaagtcct   1320

cctattccag tgtccatgtt ggcctccagt ccttaatgtc accatgcttg tggccaatgc   1380

atccaaataa ggatacccct cagggctcag ctagacattg caattttgca tagctttcca   1440

gttccctttg cttgtcttct tgactgtctt ccctctctat cggggtcact tgcaattgtt   1500

aatcaaagat tgaacactgc gtaggagagg gagatgatcc agagacatgt ggcagcaggc   1560

atggcttccc cttggcctct ctgtacactg ccccaggact gtcattttgg catctgcaaa   1620

ggaatcactt tagaaagcca gcacctggtt gatgtgtatt catactgaca ttagattgat   1680

gtgcactgca ttagaaatga ggtagctgac acagaaaaag gatgttttga taggaataat   1740

tttctagtat gtcttgaaac atgttcatct ggaagtattt tcctccaaag taatgtagca   1800

tgatttttca aggattgtta acatgcctgg gattgggaaa gataggacta aagttgtgcc   1860

aaactatatc aataaattcc atgtttagca gaaataggca gcctattggt gttatgttta   1920

tgtaacatag tccagagaac tgacatgcag gtcaaaagtc agatacgcaa cctccttatc   1980

tgctaactct gttattcttc aaacacaagt gggtagtgtc atttttcctt ccttccttcc   2040

attggcagat tgtatattta ttcacaaaac attaaatgtc catcctgtgc caggtactat   2100

gcagatgttg agggatttgg ggtctggtta gtcgtgacta tctatcctga atctaacagt   2160

gacttcataa ctaggagact gaattagacc cttaaggtat agtgtgtgtt gcaaatcact   2220

ctgcaatgga aacttttata ttcagggtag gtttgtgtct taaactaggt gttctaatca   2280

atgtacaaga ctttaccata cacgcaacta tagtttttct aaaccttcat cattttgtga   2340

ttctttgaga aagggctttt aggaacttta tgttctaaaa aatgttttta acaataataa   2400

gataaaagaa aaacctgtga ttcatatgtc cccactggca ttactcagca ggagccccca   2460

gctgccaaag gttggcagtg atcctgcaag ttcaagggct ctttctccct ggggatgtgc   2520

tttgtggctt ctctttacag ctttgtttct gcatcagttc actgctgcat gttgtttgga   2580

atttatcacc ttaagaaagt gtctctgttt tatatagaaa cactttctca cttacagggg   2640

agaaggaaat gcagggcaca tgatctggcc ctccccagaa caatctggat ttcacggaga   2700

cagcaaccag aagttaaacc atgtgactaa aaatgcatct ggctactttt tcatgtatgt   2760

atgagacaga aactaatcct tactatccta ttaggatacc acttttcatt gcaaagtttg   2820

tgtcaataaa gtcattaatt ttaaacataa aaaaaaaaa                          2859


<210>  757
<211>  2608
<212>  DNA
<213>  Human

<400>  757
gcggagctcc gcatccaacc ccgggccgcg gccaacttct ctggactgga ccagaagttt     60

ctagccggcc agttgctacc tccctttatc tcctccttcc cctctggcag cgaggaggct    120

atttccagac acttccaccc ctctctggcc acgtcacccc cgcctttaat tcataaaggt    180

gcccggcgcc ggcttcccgg acacgtcggc ggcggagagg ggcccacggc ggcggcccgg    240

ccagagactc ggcgcccgga gccagcgccc cgcacccgcg ccccagcggg cagaccccaa    300

cccagcatga gcgccgccac ccactcgccc atgatgcagg tggcgtccgg caacggtgac    360

cgcgaccctt tgccccccgg atgggagatc aagatcgacc cgcagaccgg ctggcccttc    420

ttcgtggacc acaacagccg caccactacg tggaacgacc cgcgcgtgcc ctctgagggc    480

cccaaggaga ctccatcctc tgccaatggc ccttcccggg agggctctag gctgccgcct    540

gctagggaag gccaccctgt gtacccccag ctccgaccag gctacattcc cattcctgtg    600

ctccatgaag gcgctgagaa ccggcaggtg caccctttcc atgtctatcc ccagcctggg    660

atgcagcgat tccgaactga ggcggcagca gcggctcctc agaggtccca gtcacctctg    720

cggggcatgc cagaaaccac tcagccagat aaacagtgtg gacaggtggc agcggcggcg    780

gcagcccagc ccccagcctc ccacggacct gagcggtccc agtctccagc tgcctctgac    840

tgctcatcct catcctcctc ggccagcctg ccttcctccg gcaggagcag cctgggcagt    900

caccagctcc cgcgggggta catctccatt ccggtgatac acgagcagaa cgttacccgg    960

ccagcagccc agccctcctt ccaccaagcc cagaagacgc actacccagc gcagcagggg   1020

gagtaccaga cccaccagcc tgtgtaccac aagatccagg gggatgactg ggagccccgg   1080

cccctgcggg cggcatcccc gttcaggtca tctgtccagg gtgcatcgag ccgggagggc   1140

tcaccagcca ggagcagcac gccactccac tccccctcgc ccatccgtgt gcacaccgtg   1200

gtcgacaggc ctcagcagcc catgacccat cgagaaactg cacctgtttc ccagcctgaa   1260

aacaaaccag aaagtaagcc aggcccagtt ggaccagaac tccctcctgg acacatccca   1320

attcaagtga tccgcaaaga ggtggattct aaacctgttt cccagaagcc cccacctccc   1380

tctgagaagg tagaggtgaa agttccccct gctccagttc cttgtcctcc tcccagccct   1440

ggcccttctg ctgtcccctc ttcccccaag agtgtggcta cagaagagag ggcagccccc   1500

agcactgccc ctgcagaagc tacacctcca aaaccaggag aagccgaggc tcccccaaaa   1560

catccaggag tgctgaaagt ggaagccatc ctggagaagg tacaggggct ggagcaggct   1620

gtagacaact ttgaaggcaa gaagactgac aaaaagtacc tgatgatcga agagtatttg   1680

accaaagagc tgctggccct ggattcagtg gaccccgagg gacgagccga tgtgcgtcag   1740

gccaggagag acggtgtcag gaaggttcag accatcttgg aaaaacttga acagaaagcc   1800

attgatgtcc caggtcaagt ccaggtctat gaactccagc ccagcaacct tgaagcagat   1860

cagccactgc aggcaatcat ggagatgggt gccgtggcag cagacaaggg caagaaaaat   1920

gctggaaatg cagaagatcc ccacacagaa acccagcagc cagaagccac agcagcagcg   1980

acttcaaacc ccagcagcat gacagacacc cctggtaacc cagcagcacc gtagcctctg   2040

ccctgtaaaa atcagactcg gaaccgatgt gtgctttagg gaattttaag ttgcatgcat   2100

ttcagagact ttaagtcagt tggtttttat tagctgcttg gtatgcagta acttgggtgg   2160

aggcaaaaca ctaataaaag ggctaaaaag gaaaatgatg cttttcttct atattcttac   2220

tctgtacaaa taaagaagtt gcttgttgtt tgagaagttt aaccccgttg cttgttgttc   2280

tgcagccctg tctacttggg cacccccacc acctgttagc tgtggttgtg cactgtcttt   2340

tgtagctctg gactggaggg gtagatgggg agtcaattac ccatcacata aatatgaaac   2400

atttatcaga aatgttgcca ttttaatgag atgattttct tcatctcata attaaaatac   2460

ctgactttag agagagtaaa atgtgccagg agccatagga atatctgtat gttggatgac   2520

tttaatgcta cattttaaaa aaagaaaata aagtaataat ataactcaaa aaaaaaaaaa   2580

aaaaaaaaaa aaaaaaaaaa aaaaaaaa                                      2608


<210>  758
<211>  1729
<212>  DNA
<213>  Human

<400>  758
gcgggcgggt gcgcgcgctt tctcgcgcac gcgcgcacgg agggggcgac ggccgctgtg     60

acgctgcggc ggcggcgggc gggcggcggc gcgtgaggcg cgcgatcccc ggtgtcttgg    120

gagcagtgcc ccggcccccg ccgctcccgc cgccgccatg tcgggccggt cggtccgggc    180

ggagacccgc agccgggcca aggacgacat caagaaggtg atggcggcca tcgagaaagt    240

gcggaaatgg gagaagaagt gggtgactgt gggtgacacg tccctgagga tatttaagtg    300

ggttcctgtg acagacagca aggagaaaga aaagtcaaaa tcgaacagtt cagcagcccg    360

agaacctaat ggctttcctt ctgatgcctc agccaattcc tctctccttc ttgaattcca    420

ggacgaaaac agcaaccaga gttccgtgtc tgacgtctat cagcttaagg tggacagcag    480

caccaactca agccccagcc cccagcagag tgagtccctg agcccagcac acacctccga    540

cttccgcacg gatgactccc agcccccaac gctgggccag gagatcctgg aggagccctc    600

cctgccctcc tcggaagttg ctgatgaacc tcctaccctc accaaggaag aaccagttcc    660

actagagaca caggtcgttg aggaagagga agactcaggt gccccgcccc tgaagcgctt    720

ctgtgtggac caacccacag tgccgcagac ggcgtcagaa agctagcacc atcccggccc    780

tccgcctcct ggccctgcct ctatttattg cattctggtt ctggccgcgc cgcgttgctg    840

gggtaagggc aagcactggg gtcaagagcc tgcacacatg agccttccgg gctggaaggc    900

tggcgtagga cttggggctg tagcatcatc ttcctgaccc tggcacctgt gtctacttgc    960

tcccgagaag aggagcgctc atgtcttttt tgcaccccaa gttggctgga gcatcggcca   1020

ccccaagatt catctgtgac ctccaggcag cagtctctgc tccagaatct ctggacggag   1080

ctgctggcag cttctgcgag aagagagaga tgtggaaggc accttctaga agagagcgtg   1140

cctcaggtta cttgaacttg aacggagact gtagactccc ggactttccc ctaggactgg   1200

gggccctgta ggctgctgtt ggaggactgg gtagagacat tggagggaag ggaagggctt   1260

ttctccacac aagggcagag agtccgtcta gatttcttgc tgtcctgcca gctctgccca   1320

tgcctgaggt ggtcctacct ctcacgggca ccctagctgc tgacagccct ttgtggccgc   1380

cgtccccatc ccctgccctc agcacacaca tctgcacaca cgcagctttg ttctcacctc   1440

tacctgtcat tccagcatcc ctgcctcttg tcacaaactg ccccagcaag aatttgaggt   1500

tctgacaaca gtacccatcc cccacagtac cccttcagct cagtttctag aaagctccct   1560

tttctttgaa atctgcatgt tgaattgaac tttgtgattt tattttttgt ttcaaaaaag   1620

tttaagaaaa tggaaatggg caacagtgag tgaagacata ttttagcact gaatagaata   1680

tttttaaaat taaactattt gaaatatgtc caaaaaaaaa aaaaaaaaa               1729


<210>  759
<211>  2589
<212>  DNA
<213>  Human

<400>  759
gtcggaagtc aaaggtcagt aaatagtggt gatgtcatgc aggcaagatg gcggaagggg     60

aggacgtggg atggtggcgg agctggctgc agcagagcta ccaagcagtc aaagagaagg    120

ctcgcctcta tagcctgcag tcggacccag caacctactg taatgaacca gatgggcccc    180

cggaattgtt tgacgcctgg ctttcccagt tctgcttgga ggagaagaag ggggagatct    240

cagagctcct tgtaggcagc ccctccatcc gggccctcta caccaagatg gttccagcag    300

ctgtttccca ttcagaattc tggcatcggt atttctataa agtccatcag ttagagcagg    360

agcaggcccg gagggacgcc ctgaagcagc gggcggaaca gagcatctct gaagagcccg    420

gctgggagga ggaggaagag gagctcatgg gcatttcacc catatctcca aaagaggcaa    480

aggttcctgt ggccaaaatt tctacattcc ctgaaggaga acctggcccc cagagcccct    540

gtgaagagaa tctggtgact tcagttgagc ccccagcaga ggtgactcca tcagagagca    600

gtgagagcat ctccctcgtg acacagatcg ccaacccggc cactgcacct gaggcacgag    660

tgctacccaa ggacctgtcc caaaagctgc tagaggcatc cttggaggaa cagggcctgg    720

ctgtggatgt gggtgagact ggaccctcac cccctattca ctccaagccc ctaacgcctg    780

ctggccacac cggcggccca gagcccaggc ctccagccag agtagagact ctgagggagg    840

aggcgcccac agacttacgg gtgtttgagc tgaactcgga tagtgggaag tctacaccct    900

ccaacaatgg aaagaaaggc tcaagcacgg acatcagtga ggactgggag aaagactttg    960

acttggacat gactgaagag gaggtgcaga tggcactttc caaagtggat gcctccgggg   1020

agctggaaga tgtagagtgg gaggactggg agtgagggag ccagagggag cagctccccc   1080

acccatggca tctctcgcct ccctcgctcg tctcagccca gccctggaag actgagaatg   1140

ttcccccaaa tctcctctgc caaccagagc tctgggcaca gattctggtg gctccctgct   1200

ggccctcttg ggcctctgct cacacctggg aaggggctct ctaaatcccg gccagaaact   1260

ctgacttgtg ccaacaatag gatgacccaa gggagaggaa acctatcctc ctcaccagaa   1320

gagcctgtgt ttttctgctg aacacccact gttcctgagg actcctgctg ggaagtccca   1380

agggatagtt ctagcccttc tgcctgtgta gacagaagct aaaccaccag tctctctcgg   1440

aggaagctga gacaacatac tctgtccata cataagcagg cagggagggc catgccacct   1500

acccttggct aaacagggac agtgaacaca ttttggttcc tatcccagtg ggtaagaggc   1560

acttatctct gggaaatttg cctctcttgg gactctcccc ctcccaggca ttttccattc   1620

ctggaaaggc tcctttgggg ttcagaatcc agagaccaaa ccctgaccca cctccttcct   1680

ttcctccagc ccacgctggt ctgtccccat gccttcccag ggcttcttca tgtcggatgc   1740

acccaagtcc ttagcccagc tgtgccacct gcaggagttc gctcttgcgt ttcttcccct   1800

ccccaagaag ggagggggct acttcaggcc cttctgtgtg ttgcctggca ggataccttg   1860

tccaaccagc tacccacctc aactcccctg tagtttagga cacaaaacag ctaccagcgg   1920

tacagagcgg tgatcaaagc cgagtactta caactctggt aagcctagct tctccgcctc   1980

agcccttctg cttctggaag ggctatcctg ggggtgaact tgaaactctc atcaggcttc   2040

tgcaaaagct cttcttcctg aagacagacc cagcctttgt gctctcaccc tccactctgg   2100

taaagctgca cctctggggg aatgaggggc tgcaggaatc tctggagagc ctggtgcttc   2160

acgatgctgc tctggtgatt cttgtaccta atctggtgtg ctcaccaatg agtgaaaggg   2220

atcgtgggtc agggacaccg agagagtgag gtcacttcca cttcaaacct tcagtgaggg   2280

ggtgggatgg agagaatgct gaatcttttt tttgacggga tggggttttt ctctttgtaa   2340

ttatttcttt agtttaatta accttttggt tgtttgtgca atattatata ttttaaatta   2400

taatgcatct ccccagagta ttttgtagct gggaaaagaa aaaaggaaaa aaagaaaaaa   2460

agattctaac agctgttagt tttataatta aaaaagaaag aaaaaagaac tttgtcctga   2520

accttttaca gacttgccgt taacagcatt aaagtgattc acccgaagct gaaaaaaaaa   2580

aaaaaaaaa                                                           2589


<210>  760
<211>  2402
<212>  DNA
<213>  Human

<400>  760
gagccgctgg cgccactaga gaagggcgag cggcgcggca gagtgcggcg cagcgcagct     60

cctgaggttt tggttatgaa caggattcgg attcacgtct tgccaaccaa tcgggggagg    120

atcactccag tgcccaggtc tcaggaacct ctgtcttgtg cattcactca tcgtccatgc    180

tctcaccctc gtctggaggg gcaggagttt tgcattaagc atatccttga agacaagaat    240

gcacccttca agcagtgtag ttatatatcg acgaagaatg gaaaaagatg tcccaatgct    300

gccccaaagc cagagaagaa agatggggtg tccttctgtg ctgaacatgt ccgtaggaat    360

gccctggcac ttcatgctca aatgaagaag accaacccag ggcctgtggg tgaaacactc    420

ctgtgccagc tgagctcata tgctaagaca gagctggggt ctcagactcc agaaagtagt    480

cgcagtgaag ccagccgaat actagatgaa gacagctgga gtgatgggga gcaggaaccc    540

attactgtgg atcagacatg gagaggtgac cctgacagtg aagctgatag catagacagt    600

gatcaagaag atcccctaaa acatgctggt gtctacacag cagaagaagt ggccctgatt    660

atgcgtgaaa agctaattcg tttgcagtcg ttgtatattg atcagtttaa acgacttcag    720

catctgctca aggagaagaa gcgccgatac ttacataatc gcaaagtgga acatgaagct    780

ctaggcagta gtctcctgac tggcccagag ggacttttgg ccaaagaacg agagaactta    840

aagcgattaa aatgtctgcg acgataccgc cagcgctatg gagtggaagc cttactgcat    900

aggcagttga aggaacggag aatgctggcc acagatggtg ctgcccaaca ggcccatacc    960

actcgttcca gtcagaggtg cttggccttt gtggatgatg ttcgttgttc caatcagtct   1020

cttccaatga ccagacactg ccttacccat atttgtcagg atacgaatca ggttctcttc   1080

aagtgctgcc agggatctga agaggtaccc tgcaacaaac ctgttcctgt aagcctctct   1140

gaggatccct gctgcccact gcatttccag ttgcctcctc agatgtataa gcccgagcag   1200

gtactgtctg tgccagacga tctggaagcc ggccccatgg atctgtactt gagtgctgct   1260

gagcttcagc ccactgagag tttacctctg gagttcagtg atgacttgga tgttgtgggt   1320

gatggtatgc agtgtcctcc ttcacctttg ctttttgatc cttcactaac ccttgaagat   1380

catttagtca aagaaattgc tgaagaccca gtggatattt tgggccagat gcagatggct   1440

ggagatgggt gcagatccca gggatctcga aattctgaga aagcctctgc accattgtct   1500

cagagtggat tggctactgc aaatgggaag ccagaaccca cttctattag ttgatagttt   1560

ggggaaccat tttactttgg tggatttaaa tttctcgttc ttcaaagaag tatttctgat   1620

catctctcac aaaacacagg caacccagac taccttgttt ttcttctgga ttgagtatta   1680

tagtcaaacg taaagccaaa ttttgaggac gtggaccgtg ggtttcttcc cactcagggc   1740

aaggaagaga aagagagata atccctatca aagcttctgg gattatttgg gactatacct   1800

aaaaggaaag tgacatcttt gtaatgggat ttcccaagtc atggatagaa atccacttaa   1860

gtagctaggt gggagctgtc tttgtgagtg gtgtctttga gatactgatg gccctaatat   1920

cggttatctc tatctgaaga cctgcagttt agcttttctt cacctctact taattgggca   1980

gtctttaacc cctttccctg gtgaactctg gctttttatc ctctgagaaa acagcccaca   2040

ggactgggtc ctccttatcc gtcttgcttt taacctatgt aaatttctgt ggttgctatc   2100

ttatgtaaaa tatagtaaaa atttattgta tatagtttct attaaatgtt aaagaaaatg   2160

ttatgaaaat atcaaacagt cacctgaatt gaatgcatgt tttgtttgag aatatagttt   2220

ctttttcgcg gttttgggga cctgtctctg atgggaaagg gaagttggga cagatgatac   2280

ttccatccca agaagtaaat aaatcttcag tagctcattt tggttttgct ttgaaggaag   2340

aagtaaatga aaaggggcag gacttattaa agcccatcag ttccaaaaaa aaaaaaaaaa   2400

aa                                                                  2402


<210>  761
<211>  900
<212>  DNA
<213>  Human

<400>  761
tttcttcctt ctggctggcc ggccgcaggg tagggggtcc gtggacctcc cggcctgtag     60

ggggcgtcgg gcgcagcgga agggcctgct ccggagcctg gccagggctg cgcagtcatg    120

atcaccgaga ccgcggcgga gcctacggtc cctgcagtgc ctgctgctga ggaggccacc    180

gaagctcggg gacgcgagga gccggcgtgg ccctggaaag acgccccgat ccggacgctg    240

gtgcagcgca tccaccagct gcaggctgag cgcgcgcagg gcttccgccg actggaggag    300

tggttggcgc cggtgcaggg cctgagagcc tgggggcgcg gcctcagggt ccccacatgc    360

cgcagaggcc accgccagta cctgcgcagc ggccctgact acgacttcgc gcgctaccgg    420

agcacagtgc acggggtgac ccaggccttc gccgccgcct cgcgggaggt gctggcggtg    480

gaagcagagc tgggcgggcc tcgcaggcag ccgctgctcg ccggccacgt gcgcagcctg    540

caggagctgg agcagacgcg gctgggcacg gtggccctgc tgcagttgat ggagacgcca    600

gagctggcgg ggcaggagga cgctgtacgg atgcagcagc tgaaaatgaa ggtaattaaa    660

accatggagg cgatcagcga ggttctccag gaccttaggt ttgatgcgga atctgccgag    720

tgatggcggc tccccaggga tgcgccgagg gagatgggaa acggggcgga tggcgcccag    780

cccagcccta actgccagct ggctggggtt gcgccccact gcgctgctga ccttcctgca    840

gttccagaca cctcccacaa taaagagctc ctcctctgta aaaaaaaaaa aaaaaaaaaa    900


<210>  762
<211>  694
<212>  DNA
<213>  Human

<400>  762
gacatcacca agggcctggc accaggtgcc cagtcttcca gttgcgaggg caagcaaacc     60

cgtcatgagc aactcccttc cccatctctg ctcaccatgt ggacgctgaa atcgtccctg    120

gtcctgcttc tgtgcctcac ctgcagctat gcctttatgt tctcttctct gagacagaaa    180

actagcgaac cccaggggaa ggtgccgtgt ggagagcact ttcggattcg gcagaaccta    240

ccagagcaca cccaaggctg gcttgggagc aaatggctct ggcttttgtt tgctgttgtg    300

ccgtttgtga tactgcagtg tcaaagagac agtgagaaga ataaggagca gagtcctcct    360

ggccttcgag gcttcccatt tcgcactcca ctaaagaaaa atcaaaatgc ttctctttac    420

aaagactgtg tattcaatac cttaaacgaa cttgaagtgg agcttttgaa atttgtgtcc    480

gaagtgcaga atcttaaagg tgccatggca acaggcagtg gcagtaacct caagcttcga    540

aggtcagaga tgcctgcaga tccataccat gtcacaatct gtaaaatatg gggagaagaa    600

agctctagct gaatggattt gtgtgtcagg agagaaaaaa gttgagtgtt gacaaactgt    660

atgcaaacta ataaaactat tctgaagaaa agaa                                694


<210>  763
<211>  1203
<212>  DNA
<213>  Human

<400>  763
ccgcgttccg gttgcggatg gtgagtgtgt cggggggctt ggcggctttt ctcctcagtt     60

ttctggagtg ctttggagga gaggactatg gcagccaggg acgccacttc aggcagcctg    120

tcagaggaga gcagtgcttt ggacctgcca tcagcgtgtg acataagaga ttacgtcctg    180

cagggaccca gccaagaagc caacagcgag gctttcagtt ctttggaatt ccattctttt    240

ccttattctt ctgatgtgga tccagacacc agtaacttaa atatagaaca aaataactcc    300

tggaccgctg agaacttctg gcttgaccct gctgtgaaag gccagtcaga gaaggaagag    360

gatgatggcc ttcggaaatc cctggataga ttctatgaaa tgtttggtca tccacagcca    420

ggctctgcaa actcactctc tgcatctgtc tgcaagtgcc tgtctcagaa aatcactcaa    480

ctaagaggcc aggagagcca aaagtatgcc ctccgcagtt ttcaaatggc ccgggtgatc    540

ttcaaccggg acggctgctc cgtcttacag aggcattcca gggacaccca cttctaccca    600

ctggaggaag gaagtacatc tttggatgat gaaaagccaa acccaggact gtcaaaggat    660

attactcatt tcctcttgca gcagaatgta atgaaagacc tgtaactggt gccgggcggt    720

gtgcagggta gtaatggagg tgctgtgcca tgaccagcag tgttggtggc cacccagatc    780

ccctagggtc tctggccagc tctgtgtgcc caatcccaat taagtgcttt gaggttaaag    840

gctggcacct gtgacctggt attggagcca gtcagcccat atggagagcc agcagggtct    900

gggagttctc cgtcctcttg gccaaggccg ctgactgact gggctacgag tcaaaagccc    960

agctcccttg cctcaaggaa ggacattctc tgaggagtaa tttatgctct agcactccct   1020

ttcctctaga tcggcctgag gctgggacat tacatgaaat cacacccttg ctgggcttaa   1080

tccctttccc taccctccca tttatttact ggtgtctctg ggagcctttc cttaataaac   1140

ctcttatatc tgaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1200

aaa                                                                 1203


<210>  764
<211>  1654
<212>  DNA
<213>  Human

<400>  764
agcgtgctgc gtcacggcgg tgcgccggaa gtggctgcgg atttcgccgg aaatcccgga     60

agtgacagct ttgggggttt gctgctggct ctgactcccg tcctgcgatg ggttgcgacg    120

ggggaacaat ccccaagagg catgaactgg tgaaggggcc gaagaaggtt gagaaggtcg    180

acaaagatgc tgaattagtg gcccaatgga actattgtac tctaagtcag gaaatattaa    240

gacgaccaat agttgcctgt gaacttggca gactttataa caaagatgcc gtcattgaat    300

ttctcttgga caaatctgca gaaaaggctc ttgggaaggc agcatctcac attaaaagca    360

ttaagaatgt gacagagctg aagctttctg ataatcctgc ctgggaaggg gataaaggaa    420

acactaaagg tgacaagcac gatgacctcc agcgggcgcg tttcatctgc cccgttgtgg    480

gcctggagat gaacggccga cacaggttct gcttccttcg gtgctgcggc tgtgtgtttt    540

ctgagcgagc cttgaaagag ataaaagcgg aagtttgcca cacgtgtggg gctgccttcc    600

aggaggatga tgtcatcatg ctcaatggca ccaaggagga tgtggacgtg ctgaagacaa    660

ggatggagga gagaaggctg agagcgaagc tggaaaagaa aacaaagaaa cccaaggcag    720

cagagtctgt ttcaaaacca gatgtcagtg aagaagcccc agggccatca aaagttaaga    780

cagggaagcc tgaagaagcc agccttgatt ctagagagaa gaaaaccaac ttggctccca    840

aaagcacagc aatgaatgag agctcttctg gaaaagctgg gaagcctccg tgtggagcca    900

caaagaggtc catcgctgac agtgaagaat cggaggccta caagtccctc tttaccactc    960

acagctccgc caagcgctcc aaggaggagt ctgcccactg ggtcacccac acgtcctact   1020

gcttctgaag cccgcactgc caccgctcct gccccagaag gttgtttagt ttccacgtag   1080

gcaggtcgct ttgtgcctct gagtgcgctg ctgtgtgttc tctctatagt tctgtgtcat   1140

aaagctgtcc tggccagcct tcaagctggt gtggccactc ttgatgtgag gcgtgtcggt   1200

tccagggggg acatgggagg ggctgcacag tggcccgagg tcatgcttgc ttccacctgc   1260

aggtgcattt ggtcctttcc atggccagga agccctgtgg gctgcacttt ttatgcttgc   1320

agtaacaaga gactccagag tcctcaccgg tgcagagttg gcacatatta attaactaaa   1380

attctaatga tcttgctacc agcaataaat caagtaggcc aagtgaaact gggctttaaa   1440

aaggatggat ttcaaataca ctgtgcccac tagaagcttc gaagggcctc gtccctctgc   1500

tacagccctg ggaggagcca ggatccttgt tggtctagct aaatactgtt aggggagtgt   1560

gccccatctc atcatttcga agatagcaga gtcatagttg ggcacccagt gattgggttc   1620

aaaaataaag ctggtctgcc tcttctctca aaaa                               1654


<210>  765
<211>  3148
<212>  DNA
<213>  Human

<400>  765
cctcccgtcc cgccgagccg gcgccaagat ggcggcgctg actcctggag agcggtcgcg     60

ccggaggccg cgggggccgg agcggagcag ccgcggctga ggttcccgag tcgccgctcg    120

gggctgcgct ccgccgccgg gaccccggcc tctggccgcg ccggctccgg cctccggggg    180

ggccggggcc gccgggacat ggtgccagtc gcaccccttc cccgccgccg ctgagctcgc    240

cggccgcgcc cgggctggga cgtccgagcg ggaagatgtt ttccgccctg aagaagctgg    300

tggggtcgga ccaggccccg ggccgggaca agaacatccc cgccgggctg cagtccatga    360

accaggcgtt gcagaggcgc ttcgccaagg gggtgcagta caacatgaag atagtgatcc    420

ggggagacag gaacacgggc aagacagcgc tgtggcaccg cctgcagggc cggccgttcg    480

tggaggagta catccccaca caggagatcc aggtcaccag catccactgg agctacaaga    540

ccacggatga catcgtgaag gttgaagtct gggatgtagt agacaaagga aaatgcaaaa    600

agcgaggcga cggcttaaag atggagaacg acccccagga ggcggagtct gaaatggccc    660

tggatgctga gttcctggac gtgtacaaga actgcaacgg ggtggtcatg atgttcgaca    720

ttaccaagca gtggaccttc aattacattc tccgggagct tccaaaagtg cccacccacg    780

tgccagtgtg cgtgctggga aactaccggg acatgggcga gcaccgagtc atcctgccgg    840

acgacgtgcg tgacttcatc gacaacctgg acagacctcc aggttcctcc tacttccgct    900

atgctgagtc ttccatgaag aacagcttcg gcctaaagta ccttcataag ttcttcaata    960

tcccattttt gcagcttcag agggagacgc tgttgcggca gctggagacg aaccagctgg   1020

acatggacgc cacgctggag gagctgtcgg tgcagcagga gacggaggac cagaactacg   1080

gcatcttcct ggagatgatg gaggctcgca gccgtggcca tgcgtcccca ctggcggcca   1140

acgggcagag cccatccccg ggctcccagt caccagtggt gcctgcaggc gctgtgtcca   1200

cggggagctc cagccccggc acaccccagc ccgccccaca gctgcccctc aatgccgccc   1260

caccatcctc tgtgccccct gtaccaccct cagaggccct gcccccacct gcgtgcccct   1320

cagcccccgc cccacggcgc agcatcatct ctaggctgtt tgggacgtca cctgccaccg   1380

aggcagcccc tccacctcca gagccagtcc cggccgcaga gggcccagca acggtccaga   1440

gtgtggagga ctttgttcct gacgaccgcc tggaccgcag cttcctggaa gacacaaccc   1500

ccgccaggga cgagaagaag gtgggggcca aggctgccca gcaggacagc gacagtgatg   1560

gggaggccct gggcggcaac ccgatggtgg cagggttcca ggacgatgtg gacctcgaag   1620

accagccacg tgggagtccc ccgctgcctg caggccccgt ccccagtcaa gacatcactc   1680

tttcgagtga ggaggaagca gaagtggcag ctcccacaaa aggccctgcc ccagctcccc   1740

agcagtgctc agagccagag accaagtggt cctccatacc agcttcgaag ccacggaggg   1800

ggacagctcc cacgaggacc gcagcacccc cctggccagg cggtgtctct gttcgcacag   1860

gtccggagaa gcgcagcagc accaggcccc ctgctgagat ggagccgggg aagggtgagc   1920

aggcctcctc gtcggagagt gaccccgagg gacccattgc tgcacaaatg ctgtccttcg   1980

tcatggatga ccccgacttt gagagcgagg gatcagacac acagcgcagg gcggatgact   2040

ttcccgtgcg agatgacccc tccgatgtga ctgacgagga tgagggccct gccgagccgc   2100

ccccaccccc caagctccct ctccccgcct tcagactgaa gaatgactcg gacctcttcg   2160

ggctggggct ggaggaggcc ggacccaagg agagcagtga ggaaggtaag gagggcaaaa   2220

ccccctctaa ggagaagaag aagaagaaga aaaaaggcaa agaggaagaa gaaaaagctg   2280

ccaagaagaa gagcaaacac aagaagagca aggacaagga ggagggcaag gaggagcggc   2340

gacggcggca gcagcggccc ccgcgcagca gggagaggac ggctgccgat gagctggagg   2400

ctttcctggg gggcggggcc ccgggcggcc gccaccctgg gggtggcgac tacgaggagc   2460

tctaggccgg cgtgggcagt ggccgccctg gggcgggggg cgtgcctgtc actgcctggg   2520

gaggcatttg cctctgtacc atcgcctttg ccgctgcccc gtggctgccg tgtgcgcttc   2580

tgagctggaa gaggccgggc attggtggtc cccaggctgg gccctgcagg tgctgggcct   2640

tcaggcccag tgtgagcctg ctctgcaaga agggagggga cagctggctt cagccaggct   2700

cggtggacac cctggccctc tcggggcaga gccgccagtg tttctcaggg atgtgactga   2760

ggcccaggag ggacctgtga gggtctgttt acagaggctg ggcaggggcc gcttggctgt   2820

ggggtgtgcg ctgccccggc acctgcttgc cctccgcgct catctggggc cgcagcatgc   2880

ctatggttcc gcttccggcc gggagccctg aacacgggtg tgcagactca ccctaaaggg   2940

cggcccaggc cccacgctag aaggctggcg agaccgaagg cagcatgtga ggcctctcct   3000

gggagtgggg gttgtgtttc ccacagtggc ctcagctgcg cccccgctca ggtgagcccg   3060

aaggcaggag ccgggaggca ctcctcccaa acactccact cagaccataa agcactcctg   3120

tttcactctg aaaaaaaaaa aaaaaaaa                                      3148


<210>  766
<211>  7222
<212>  DNA
<213>  Human

<400>  766
agccggacgg cgcggtggtc gggacagact ggccgttgct gtggagacgc ctggagagtt     60

gtggactggg gcaacctttg ccagtgatga gaagtgatgc tcgtggcagt gctgaatctc    120

tctgaatatg attcgaattg cagccttaaa tgccagctcc accattgagg atgatcatga    180

aggaagcttt aaaagtcaca aaacccagac aaaggaggct caggaagcag aggcttttgc    240

attgtaccac aaggcccttg atctgcagaa acatgaccgg tttgaggagt ctgccaaagc    300

ctaccatgag ctcttggagg cgagcctgct gcgggaggca gtttcatccg gtgatgagaa    360

agaggggttg aaacaccctg ggctgatact gaaatattcc acttataaga acttggccca    420

gctggcagcc cagcgggagg atctggagac agccatggag ttctacttag aggcagtgat    480

gctggactcc acagatgtca acctctggta taagattgga catgtggccc tgaggctcat    540

ccggatcccc ctggctcgcc atgcttttga ggaagggctg cggtgcaatc ctgaccactg    600

gccctgtttg gataacctaa tcactgtcct gtacaccctc agtgattaca caacatgtct    660

gtacttcatc tgcaaagctt tggagaagga ttgccggtac agcaaagggc tggtcctcaa    720

ggagaagatt tttgaggagc agccttgtct ccggaaggac tctctcagaa tgttcctcaa    780

atgtgacatg tcgattcacg atgtttcggt gagtgcagct gagacacagg cgattgtaga    840

tgaggccttg gggctgcgaa aaaagaggca agcgctgatt gtgcgggaga aggagccgga    900

cctgaaactt gtgcagccca ttcctttctt cacctggaag tgcctcggag agagcttgct    960

ggccatgtac aatcatctca ccacctgtga gcccccacgt cccagccttg gcaaaaggat   1020

tgatttgtcg gactaccagg accccagcca gcctcttgag tcctccatgg tggtgacgcc   1080

agttaacgtg atccagccaa gcactgtcag caccaaccca gctgtggctg tcgccgagcc   1140

tgtggtctcc tacacctctg tggctacaac cagcttccca ctgcacagtc ctggtctgtt   1200

ggagacaggc gctcctgtgg gtgatatttc tgggggagat aaatccaaga aaggggtaaa   1260

acggaagaag atttcagaag agagtggaga aacagcaaag cggcggtctg cccgtgtccg   1320

aaacaccaag tgcaaaaaag aagagaaagt agacttccag gagcttctga tgaagttctt   1380

gccgtccagg ttaagaaagc tggaccctga ggaggaagat gattccttta ataactatga   1440

agtccagtca gaagccaaac tggaaagctt cccaagcatt gggcctcaaa ggctgtcatt   1500

tgactcagcc acattcatgg aatctgaaaa gcaggacgtg catgagttcc tgctggagaa   1560

cctaaccaac gggggcatcc tggagctgat gatgcgctac ctgaaagcca tgggccacaa   1620

gttcttggta aggtggcctc caggcttggc ggaggtcgtg ctcagcgtct accacagctg   1680

gaggaggcac agcaccagcc tgcccaaccc gctgctgagg gactgcagca acaagcacat   1740

caaggacatg atgctgatgt ctctctcctg catggaactc cagctggacc agtggctgct   1800

gaccaaaggc agaagctctg cagtgtctcc tcggaactgc cctgctggta tggtgaatgg   1860

cagatttgga cctgacttcc cagggaccca ctgcctgggt gacctcctac agctgtcatt   1920

tgcctcgtcc cagcgcgacc tgttcgagga tggttggctg gagtttgtgg tccgtgttta   1980

ctggctgaag gctcgcttcc tggcgctgca gggagacatg gagcaggccc tggagaacta   2040

tgacatctgc acagaaatgc tccagagttc caccgccatc caggtggagg caggggctga   2100

acgaagagac attgtcatcc ggctgcccaa cctccataat gactctgtgg tttccctgga   2160

ggagattgat aagaacctga agtcgctgga gcggtgccag tccctggagg agattcagcg   2220

gctgtatgaa gcaggcgact acaaggctgt tgtgcatctg ctccgcccca ctttgtgcac   2280

cagtgggttt gaccgggcca aacacctgga gtttatgact tccattcctg agaggccagc   2340

ccagctgctt cttctgcagg actccttgct ccggctgaag gactatcggc agtgttttga   2400

gtgttccgat gtggctctga acgaggctgt ccagcagatg gtgaactcag gtgaggctgc   2460

cgccaaggag gagtgggtgg ccacagtgac ccaactgctg atgggcatcg agcaggccct   2520

ctctgcggac agcagtggta gcatcctgaa ggtatcatcc tccaccactg gccttgtgcg   2580

gctcaccaac aacctcatcc aggtcattga ctgcagcatg gctgtgcagg aggaggccaa   2640

ggagccccac gtctcttcag tgctaccctg gatcattcta caccggatca tctggcagga   2700

ggaagacacc ttccattctc tgtgccacca gcagcagctc caaaacccag cggaggaagg   2760

gatgtcagag acgcccatgc tcccatcctc cctcatgctg ctgaacacag cccacgagta   2820

tttgggcaga aggtcctggt gctgcaattc agatggggct ctgctgcgat tctatgtgcg   2880

agtactccag aaggaactgg ctgcatccac ctctgaagac acgcaccctt acaaggagga   2940

gctggagaca gccttggagc agtgcttcta ctgcctgtac agcttcccca gcaagaagag   3000

taaggccagg tacctggagg aacactcggc ccagcaggtg gatcttatat gggaggatgc   3060

actgttcatg tttgagtatt ttaagcccaa gacccttcct gaatttgaca gctataagac   3120

cagcaccgtg tctgctgact tggccaacct actgaagaga attgccacca ttgtgcctcg   3180

cacagagagg ccagccctta gcctggacaa agtctctgcc tacattgagg gaacttcaac   3240

tgaggtaccc tgcctcccag agggggctga cccctcccct ccagtggtga acgagcttta   3300

ctacctcctg gctgattatc atttcaaaaa caaggagcag tccaaggcca tcaagttcta   3360

catgcatgac atctgcatct gccccaatag gtttgattcc tgggcaggca tggctctggc   3420

ccgggccagc cgcattcagg acaagctgaa ctccaatgag ctgaagagtg atgggcccat   3480

ttggaagcat gccacgcccg tcttgaactg cttccgtcgg gccctggaga ttgacagctc   3540

caacttgtcc ctatggattg agtatggcac catgtcctat gccttgcact cattcgcctc   3600

acgtcaattg aagcagtgga gaggcgagct gccccctgag ctcgtgcagc agatggaggg   3660

ccggcgcgac agcatgctag agacagccaa gcactgtttc acatcagcag cccgctgcga   3720

gggtgatggt gacgaggagg agtggctcat ccactacatg ctgggcaagg tggctgagaa   3780

gcagcagcag ccacccaccg tttacttgct gcactacagg caggctggcc actacctgca   3840

cgaggaggct gcccgctacc ccaagaagat ccactaccac aacccacctg agctggccat   3900

ggaggccctg gaggtgtact ttcggctcca tgcttccatc ctgaagctcc tggggaagcc   3960

cgattctggg gttggtgcag aggtcctggt caactttatg aaggaggctg cagaaggacc   4020

ctttgccagg ggcgaggaga agaacacacc caaagcttca gaaaaggaga aggcctgcct   4080

ggtggacgag gactcccact cttcagctgg gacactgccg ggccccggag cctccctccc   4140

ctcctcctct ggcccaggtc tgacatcccc accttacaca gccactccga ttgaccacga   4200

ttacgtcaaa tgtaaaaaac cccaccagca ggcaacgccg gacgaccgaa gccaggacag   4260

cacagccgta gcactctcag actctagctc aacgcaggac ttctttaatg agcccaccag   4320

cttactggaa ggctccagga aatcctacac agagaagagg ctgcccattc tcagttccca   4380

agcaggagcg acgggtaaag atcttcaggg ggccacagaa gaaagaggaa aaaacgagga   4440

gtcattggag agtacagaag gcttccgggc tgcagagcaa ggtgtccaga agcctgctgc   4500

agaaacccca gcctctgctt gcatccctgg caagccctca gcatccacac ccaccctgtg   4560

ggatgggaag aagagagggg acctcccagg ggagccagtg gccttccccc aggggctgcc   4620

ggctggtgct gaggagcagc ggcagtttct cacagagcag tgcatcgcct ccttccgcct   4680

gtgcctgagc cgcttccccc agcactataa gagtctctac cgtctggcct tcctctacac   4740

ctacagcaag acccaccgga acctccagtg ggcccgcgac gtgttgctag gcagcagtat   4800

cccgtggcaa caactgcagc acatgccggc acaggggctc ttctgcgaga ggaacaagac   4860

caatttcttc aacggcatct ggcggatccc cgtggacgag attgaccggc cgggcagctt   4920

tgcctggcac atgaaccgct ccatcgtgct gctgctcaag gtgctggccc agctgcggga   4980

ccacagcacc ctgctgaagg tgtcctccat gcttcagcgg accccagacc agggcaagaa   5040

gtatctgcga gatgctgacc gccaggtcct ggcgcagcgg gccttcatcc tcactgtgaa   5100

ggtgctcgaa gacacgctga gcgagctcgc agaggggtca gaacgcccag ggcccaaggt   5160

ctgtggcctc cccggagcca ggatgaccac cgatgtctca cacaaggcca gtcctgagga   5220

tggccaggag ggcctccccc agccgaagaa gccccctctg gctgatggct cagggccagg   5280

gcccgagcca ggaggcaaag tgggcctcct caaccaccgg cctgtggcca tggatgcagg   5340

agacagtgca gaccaaagcg gggagcggaa ggataaagag agcccacggg cagggcccac   5400

tgagcccatg gacacgagtg aggccactgt ttgccactca gacttggagc ggacaccacc   5460

cctgctgcca ggtcgccccg caagggaccg gggccccgag agccggccca ctgagctgtc   5520

cctggaggag ctgagcatca gtgcccggca gcagcccacc ccgctcaccc cagcccagcc   5580

agcccccgcc cccgcccccg ccaccaccac agggaccagg gcagggggcc acccggagga   5640

gccgctctcc cggctcagcc gcaagaggaa gctcctggag gacacagagt caggcaagac   5700

acttctgttg gatgcctacc gtgtgtggca gcagggccag aagggtgtgg cctatgacct   5760

gggccgtgtg gagaggatca tgtcggagac ctacatgctc atcaagcagg tggatgagga   5820

ggctgcgctg gagcaggctg tgaagttctg ccaggtccat cttggggctg ccgcccagag   5880

acaggcctcg ggggacaccc ccaccactcc aaagcacccc aaagacagcc gagagaactt   5940

ctttcctgtg acagtggtgc ccacagcccc tgaccctgtg ccagctgact ctgtccagcg   6000

gcccagtgat gctcacacca agcctcgccc tgcactagct gccgccacaa ctattatcac   6060

ctgccctccg tcagcatcag cttccaccct ggaccagtcc aaggaccctg ggcctccccg   6120

gccacacagg cctgaagcta cccccagcat ggcctctctg ggcccagagg gagaagagct   6180

ggcgagagtg gcagagggca ccagcttccc gcctcaggag ccacggcaca gtccgcaggt   6240

gaagatggcc cccacaagtt ccccggcaga gccacactgc tggccggcag aggctgccct   6300

gggcacaggc gctgagccca cctgcagcca ggaggggaaa ctgaggcctg agccgagaag   6360

ggatggggag gctcaggagg ctgcgagtga gactcagccc ctgagctctc ccccaacagc   6420

tgccagctcc aaggccccca gcagtgggag tgcccagcca ccagagggtc acccaggcaa   6480

gcctgagccc agccgggcta agtcccgccc cctgcccaac atgccaaagc tggtcatccc   6540

ctccgccgcc accaagttcc cccctgagat caccgtcacg ccacccaccc caaccctgct   6600

ctcccccaaa ggcagcatct cggaggagac caagcagaag ctgaagtcag ccatcctttc   6660

tgcccagtct gctgccaacg tgaggaagga gagcctatgc cagccagccc tggaggtcct   6720

ggagacatcc agccaggagt cctcgctgga gagcgagaca gacgaggacg acgactacat   6780

ggacatttga ggggccactg cagccccacc gccacgcccc aggggaccag ccaggcctgg   6840

aatgccccct gggcaggacc ctgggcagga ccagaggccc acatggatgc cactccccac   6900

acagccccca ggcctgccca gcccacctcc tcatggcatc ctccctgtac ccaggtcagg   6960

ctgtccacac cacatgggag cccagaggag gaggggcccg ccttagccat gtgaaggtgg   7020

attggtcgcc atctgcacgc caggcggcat ccttttctat gaagtgttga ctttgtaaat   7080

ctgcccacac ccagctggcc atatccaccc ctcgacgccg ggatgagccg gctctgcctg   7140

tgtcacagtg gaggggtcct ttagggccag gctcacccct cacccttttt ttggttgctt   7200

ttctaataaa gatggaacag tt                                            7222


<210>  767
<211>  7650
<212>  DNA
<213>  Human

<400>  767
atggtggacg cgagcggccg cgccgccgcc gagggctgga ggaagatgga ggccccgccg     60

gacggcgccg ccgacctcgt gcccctggac cgctacgacg cggcgcgcgc caagatcgcc    120

gccaacctgc agtggatctg cgccaaggcc tacggccgag ataacatccc tgaggacctc    180

agagaccctt tctacgttga ccagtatgag caggagcaca ttaagccgcc tgttatcaag    240

cttctcctgt ccagcgagct gtactgccgt gtctgcagcc tcatcctgaa aggggaccag    300

gtggccgcct tacagggaca ccagtctgtc atccaggccc tgtcccggaa agggatctat    360

gtgatggaga gtgatgacac ccccgtgaca gagtccgacc tcagtcgcgc acccataaaa    420

atgagtgccc acatggcaat ggtggatgcc ctgatgatgg cctacactgt ggagatgatc    480

agcatcgaga aggtggtggc cagtgtcaag cgcttctcaa cgttcagtgc ctcgaaagaa    540

cttccgtacg acctcgagga tgccatggtg ttctggatca acaaggtaaa tcttaaaatg    600

agagagataa cagagaaaga agttaaatta aaacaacagt tattggaaag tccagctcat    660

caaaaggtcc gctatcgacg agagcacctt tctgctaggc agtcacccta cttcccgttg    720

ttggaggatt tgatgagaga cggcagtgat ggtgctgctc tcttagctgt gattcactat    780

tattgcccag agcagatgaa actggatgat atatgcttaa aggaggtaac gtcgatggcc    840

gacagtctgt ataatattcg gcttctgaga gaattctcca atgaatatct taataaatgt    900

ttttatctca ccttggaaga tatgctgtat gcgccattag tgttgaagcc gaatgttatg    960

gtttttattg cggagctttt ttggtggttc gagaatgtca agccagattt tgttcagccc   1020

agggatgttc aggagctgaa agacgcgaaa acagtgttac accagaagag cagccggcct   1080

cctgtaccga tctccaacgc gaccaaacgc agtttcctag gcagccctgc tgcagggacc   1140

ctggctgagc tgcagccccc cgtgcagctg ccggcggaag gctgtcacag gcactacctg   1200

cacccggaag aacctgaata cctcgggaaa ggaactgctg ccttcagccc atcccatcct   1260

ttattgccac tgagacagaa acagcagaaa tccatacagg gagaggacat ccctgatcag   1320

cgacatcgat cgaattcttt gacccgagtt gatggtcagc ctcgaggagc agcaatagcc   1380

tggccagaaa aaaaaaccag gcctgcgtcc cagccaacac cttttgctct acatcacgct   1440

gcgagttgtg aagtggatcc cagctctggc gacagcatca gcttggcccg ctccatcagc   1500

aaagacagtt tggcatccaa cattgttaat ctgaccccac agaaccagcc acaccccacg   1560

gccacgaaga gccacgggaa gagcctcctg agcaatgtca gtattgagga tgaggaagag   1620

gagcttgtgg ctattgttag agcagacgtg gttccccagc aggctgaccc ggagttcccc   1680

agggcctcac cccgggcctt aggccttaca gcaaatgccc ggtctcccca aggacagctg   1740

gacacctcgg aaagtaagcc tgacagtttt ttcttggagc ctttgatgcc agcagttctt   1800

aagccagcga aagagaagca ggtgatcacc aaggaggatg aacgggggga agggagaccg   1860

aggagcatcg tgtctaggag gcccagcgag ggcccccagc ctttggtacg aaggaaaatg   1920

actggcagtc gcgacttgaa taggactttt accccgattc catgctcaga attccccatg   1980

ggcatcgacc ccaccgagac aggaccactg tcagtggaaa ccgcaggaga ggtctgtggt   2040

gggcctctgg cccttggcgg attcgatccg ttcccccagg gaccatccac ggatggcttc   2100

ttccttcatg taggcagggc cgatgaagac accgagggaa ggttatatgt tagttgttca   2160

aaaagcccca actcccacga ttcagagccg tggactctcc tcaggcagga ttctgactcg   2220

gatgtggtgg acatagagga agccgagcac gatttcatgg gtgaggccca tcctgtggtt   2280

ttcagcagat acattgggga ggaagagtcg gccaaactgc aggaggacat gaaggtgaag   2340

gaacatgaag acaaagatga cgccagcggc cgctcgagcc cctgcctgag cacagcctct   2400

cagatgagca gtgtctccat ggcgagtggg agcgtgaaga tgaccagctt tgcggagagg   2460

aagctccaga gactcaacag ctgtgagacc aagtccagca ccagcagctc ccagaagacc   2520

acgccagatg cgtctgagag ctgcccagcc cctctgacga cgtggaggca gaagagggag   2580

cagagtccga gccagcatgg caaggatccc gccagcctcc tggcatctga gctggtacag   2640

ctgcacatgc agctggagga gaagcgcagg gccatcgagg cccagaagaa gaagatggag   2700

gcgctgtcgg caaggcagcg cctgaagctc ggcaaggctg cattcctgca tgtggtgaag   2760

aagggcaagg ccgaggctgc cccacccctc aggccggagc actttgcaaa ggagtactct   2820

cagcacaacg gggaggactg tggggacgct gtttccaaaa ccgaagactt tctcgtgaag   2880

gaggagcaga gagaggagct ccttcacgag ccacaggatg tggacaaaga gagcctggcc   2940

tttgctcagc aacataaagc aaaagaccct gtggctctgc acgagctgga gagaaataag   3000

gtgatctccg ctgccctcct ggaggacact gttggggagg ttgtcgacgt gaatgaatgt   3060

gacctttcca tcgagaagct taacgaaacc atcagtacgc tgcagcaggc catcctgaaa   3120

atctctcagc agcaagagca gcttctgatg aagtccccca cagtcccagt gccaggctct   3180

aagaataact cgcaggacca caaagtgaag gcaccagtcc acttcgtgga gccactctct   3240

cccacgggcg tggctggcca ccgcaaagcc ccccggctgg gtcaaggccg gaattcccgt   3300

tccggaaggc cggcggagct gaaggtccca aaagacaggc cacagggctc ctcccgaagt   3360

aaaaccccaa cgcccagtgt agagacgctc ccgcacttga gacccttccc tgccagcagc   3420

caccctcgga cgcccacgga ccctggcctg gacagtgccc tggagcccag tggtgaccca   3480

catgggaagt gtctcttcga cagttacagg ctccatgatg aaagcaatca gcggacactt   3540

actctgtcct cttccaaaga tgccaacatt ctttcggagc agatgagcct caaagaagtt   3600

ctggatgcga gtgtgaagga ggtggggtcc agctcctcag atgtctcggg aaaagagagc   3660

gtccccgtgg aggagcctct gaggagcagg gccagcctca ttgaagtgga cctctccgac   3720

ctgaaggccc ccgacgagga tggggagctg gtaagcctcg atggctcggc ggaccttgtc   3780

agcgaaggcg accagaagcc gggggtcggc ttcttcttca aggatgaaca gaaagcggaa   3840

gatgagctcg ccaagaagcg ggcggccttc ctcctgaagc agcagcgcaa ggccgaggag   3900

gcccgcgtgc gcaagcagca gctggaagcg gaggtggagc tcaagcgtga cgaagcccgg   3960

cgcaaagctg aggaagaccg ggtgcggaag gaggaggaga aggcgcggcg cgagctcatc   4020

aagcaggagt acctgcggag gaagcagcag cagatcctag aggagcaggg gctcggcaag   4080

cccaagtcaa agccgaagaa gccgcggccg aagtcggtgc accgggaaga gtcgtgcagc   4140

gactccggca ccaagtgctc ctccacccct gataacttga gccggactca gtcaggctcc   4200

agcctgtcct tggcctctgc ggcgacgaca gaacccgaga gcgttcattc cgggggcaca   4260

ccctctcagc gagtggaatc gatggaagcc ctgcccatac tgagccgtaa cccaagcagg   4320

agcacagacc gagactggga gaccgcgtcg gcggcatctt ccctggcctc agtggccgag   4380

tacacaggtc ccaagctctt taaggagccc agtagtaaat caaacaagcc gattattcac   4440

aatgccatat cccattgctg cctggctgga aaagtgaacg aaccccacaa gaattccata   4500

ttggaggagc tggagaagtg tgatgccaat cactacatca tactgtttcg tgatgctggc   4560

tgccagttca gggcgcttta ctgctactat cctgatactg aggaaatcta caaactcact   4620

ggcacggggc caaagaacat caccaagaaa atgatcgaca aactgtataa atacagctca   4680

gaccgaaaac agtttaactt gatcccagcc aaaaccatgt ctgtcagtgt ggacgcactc   4740

acaatccaca accacctgtg gcagcccaag cggcctgcag tgccaaagaa ggcccagact   4800

cgtaaatgac cccggtgcag ctggcgtcca aagggtgacc cagactcgta aatgatgccc   4860

ttgtggctgg catccagagg gtgccacggg gtccttattt attgttttca tctatttggg   4920

tacgaagtgt gcaaagtcac agaccttttg caaagaggtt tctagacagc agaagaaaac   4980

ccctctctca gcgctcatct cacgcagagg atgccaggca gggtgaggat gggggagtag   5040

atgccgcttt tgcagtggct cgcactgctg tggccactgc tgaccactga ggctcccagc   5100

ggagggtgtt cacagccagg tcccgggcca cggagctccc ttacttgaag ttctccttca   5160

gcatagatta gacgtgatcc actttgcttt cttgcttctc acctcgcccc cttgcacatt   5220

gcctgacacc ctcatattgg ccagctgtaa tctcgtgact atgggactga ggctcaatct   5280

tggcttgggg tgtttgaatg tctatagcaa aggaattcat aatgggaaat ctttttcatt   5340

tgagaaattg tatgatattt attggttgtg tctactgcca acatttatat ccaattctaa   5400

gatttctgaa aaaaaattct tatcccttgc tgctcagaaa aagtttacgg aaaacaccag   5460

ttcactaaaa gcaccgaaat ctgcaaagcc tgtcttccgc tagaacaacg tctacaaatg   5520

tgaagatgat gacttctggc acgcggtcat gagggtgggg aatggcacta ggagctgatg   5580

tttgcctcat ttaaagtagg caagccgagc caactgcagc catcattcat taagttttgg   5640

gtagtgctct aatggtttgt tcactttaat aaagacagat tttggtaaag tagaatattt   5700

ttcattctga gcatgtttgt cccaaaaggt gatgcactta agctgacagt cccttcagtg   5760

gttttgttag gtcacggctt gtcctgtctg gattctgcat ctggaagcgc tgcatgctct   5820

cagaggagcg tgccgtttcc cctgtagatg gatacttttg ttttgttgcc tatttaaaaa   5880

caattaagtg gttatttgca gttatttcag aactccaagt aagtggatgg ctttgggttc   5940

tttctgcctt ggtcccaatg gtgttgatgc ttctgtggag cgcggacatt cccaggagca   6000

ggtgcgtgcc agccatggct gccagacact gctgcaactg accagctgcc ggaagattct   6060

ggagccacta acattagttt tgcacatatt ttcttgggag tgttacttga atctatctca   6120

aactgcagaa aaaatcaaaa gatcaataat tgggagaaaa agagacaaat ttaactgtta   6180

cataatttta gatagacaaa aaacatgagt gagtcgtgta cataaggagg gaacatggta   6240

cagaaggcta gaaggaatta taggtcttat tcccctttcc tcagtccttt gaagagaagt   6300

acagtctctt gcgattttgt atatatcgtg ttcgacacag ccgctctctg tcctgtaaat   6360

agggaactaa aggctgtatg atttctcaag tgctgagtta cacagtcctg agtgagcttt   6420

ctgttaccat actttcacac gtgggcttta tttctcactg tatgtttgat atgatattac   6480

tgtatttatt ttaagaaagc actaagatgt aataaagtga tgaactaatt tgctttacat   6540

tgaatcgtat gtgtgaggtt gctgtggctc atttcgctga ccaggcgaca ccaactcctt   6600

gctttatagg agtttcacat tgttctttac catggcccta tcgaagtcag tggaattgga   6660

ttctttttaa tgaagagcta gaaaatatct ggcatagagc tggaaaattg cattcccatg   6720

ggacgtctga atcaattctg gattttctcc atggaatgag tcagtgtgtg gaacatcctg   6780

aaacttgtcc ttaagcgtgt agttttcact gttcgttgcg agtaagcact aatgtggcat   6840

ggacattcct gatgtcccaa gtccccaggc cagtgttcgc ctaatgattg acagaagcgt   6900

ccctgcgttc ttcatgcttg gacacagcaa cccttttaat tagtcttgaa aagtttcaga   6960

cacaggatta attttcgtgg tggtgctttt gggcctttct ggcttgggtg gtggtaaagt   7020

catgattttg cagttgataa cactgactta taactctgtt tatcaatgtc tcctatattc   7080

aaagcccctg cagtggtatt tgtgtctcgt tgcaaatttc tttcagcgga aagcttgcac   7140

aactttcgtt gtgtctcaga attctaacct tgttatttaa gacaagctgc tctacccatt   7200

taggatataa ctttgtaaag aaagtgtaaa ccaaatgatt caatgtatga tgaagtttat   7260

gtgtaaatcc ttggtaatgc tagaattctg ggagcccaga agggttgaaa gagaaatgaa   7320

acttgcgtga gtcccattat tttacgcatg tatgtgcaga tacgttctac ccacacgtgt   7380

gcgtgcacat ggctgtgtgc gtgcaccaaa gatggactgc tttccatgtg tccttttgac   7440

tttctgcacg tgtcactgcg gtgcagtctc ttagcagact tcaggcccaa actgtattct   7500

tcactcaggc aaaattgaaa agtggaataa ttctaaatta cttctaggtt atacttttac   7560

ctccctgaaa ttgtagttgt cacttggagg gcaaaatatt tattgaaata aaattttctg   7620

ttaaaaattc aaaaaaaaaa aaaaaaaaaa                                    7650


<210>  768
<211>  1591
<212>  DNA
<213>  Human

<400>  768
actctgggcg aggccgcccc tatcccagcc gcaccggtcc ttcccggcac acgcgaggct     60

cccatggctc tggcggtggc cccgtggggg cgacagtggg aagaggcccg cgccctgggc    120

cgggcagtca ggatgctgca gcgcctagaa gagcaatgcg tcgacccccg gctgtccgtg    180

agtccccctt cgctgcggga cctgctgccc cgcacagcgc agctgcttcg agaggtggcc    240

cattctcggc gggcggccgg cggaggcggc cccgggggtc ccggcggctc tggggacttt    300

ctactcatct acctggccaa tctggaggcc aagagcaggc aggtggccgc gctgctgcct    360

ccccggggcc gaaggagtgc caacgacgag ctcttccggg cgggctccag actcaggcga    420

cagctggcca agctggccat catcttcagc cacatgcacg cagagctgca cgcactcttc    480

cccgggggaa agtactgtgg acacatgtac cagctcacca aggcccccgc ccacaccttc    540

tggagggaaa gttgcggagc ccggtgtgtg ctgccctggg ctgagtttga gtccctcctg    600

ggcacctgcc accctgtgga accaggctgc acagccctgg ccttgcgcac caccattgac    660

ctcacctgca gcgggcacgt gtccatcttc gagttcgacg tcttcaccag gctctttcag    720

ccatggccaa cactcctcaa gaactggcag ctcctggcag tcaaccaccc aggctacatg    780

gccttcctca cctatgatga ggtccaagag cgtctgcagg cctgcaggga caagccaggc    840

agttacatct tccggcccag ctgtactcgc ctggggcagt gggccatcgg ctatgtgagc    900

tcagatggca gcatcctgca gaccatccct gccaacaaac ccctgtccca ggtgctcctg    960

gagggacaga aggacggctt ctacctctac ccagatggaa agacccacaa cccagacctg   1020

actgagctcg gccaggcaga accccagcag cgcatccacg tgtcagagga gcagctgcag   1080

ctctactggg ccatggactc cacatttgag ctctgcaaga tctgtgctga gagcaacaag   1140

gatgtgaaga ttgagccgtg cgggcacctg ctctgcagct gctgcctggc tgcctggcag   1200

cactcggaca gccagacctg ccccttctgc cgctgcgaga tcaagggctg ggaggccgtg   1260

agtatctacc agttccacgg tcaggctact gctgaggact cagggaacag cagtgaccag   1320

gaaggcaggg agttggagct ggggcaggtg cccctttcgg ctcctccatt gcccccacgg   1380

ccagatctgc cccccaggaa gcccagaaat gcccagccga aagtgagact cctaaagggg   1440

aactcccctc cagctgcgct gggaccccag gaccctgccc cggcctgaag gccagggcac   1500

ccagatgtgc tgctcaaggg agccccaagg gctggaaggg ggttgtgaaa ccgaaataaa   1560

ctgccaagcc tggtctgtcc tccagggtgc a                                  1591


<210>  769
<211>  2147
<212>  DNA
<213>  Human

<400>  769
actgcggtag gcgccctagg ggcttgcagg accctgaccc caagatggcg gcgcccagcg     60

aagtggccgc gatagcccct ggcgaaggcg atggcggagg cggcggcttt ggctcctggc    120

tggacggacg gttggaggca ctgggagtgg accgagccgt ttatggagcc tacatcttgg    180

gtatcctgca ggaggaggag gaagaagaga agctggacgc tctgcagggg atcctctctg    240

ctttcctgga agaagattcc ctccttaata tctgcaagga gattgtggaa cgatggtcag    300

aaactcagaa tgttgtcacc aaagtgaaaa aagaagatga agtacaggcc attgccaccc    360

taattgagaa gcaggcacaa atcgtagtaa agccaaggat ggtgtcagaa gaggagaagc    420

agagaaaagc tgccctcctg gcccagtatg ctgatgtgac agatgaagag gatgaagcag    480

atgagaagga tgattcaggt gctaccacaa tgaacattgg ttctgacaaa cttctgttcc    540

gaaacaccaa tgtggaagat gtccttaatg cccgaaaact ggagcgagac tcacttcggg    600

atgaatccca aaggaagaag gaacaggaca agctgcagag ggagagagac aaactagcca    660

agcaggagcg caaggaaaag gaaaaaaaaa ggacacagag aggggagcga aagcgataac    720

cttggcctac tctattcttt ccccccatga acttatcaaa gggagaactg gttgtgtatt    780

taagagaaat gagagtgcat tgcaaagtag tttcccaagg catttcccct attgtttaca    840

tggtcaaaag gaaaatcaaa atcacttcta attacaaaat gtgctgtttt ggtggggtgg    900

gcaatcagat tattatagtt gatgactgta ccaaagatct ggaatggggg ccacctttat    960

attttaatac tcaagtcctg tgctcctttt ggccacttta aaaagtcttc cctcaccttg   1020

gataaatagg attcagaaag ctaacagttt tcattctgaa ggagcagaaa cataatcaat   1080

ccctccctga gataaaatgt gggcatgcac attgctttgg agtcagtatt cagctgtaag   1140

tgtagtattg ttttatggct gaaatagaaa gctaatgaag aggcctacct ggatccagat   1200

tttatgttaa catggcagca aaactaggaa aatgggaaga aattacttgc ggggtgttct   1260

agatctgatt tttttttttt ttttgaaagt ttcagcctgt gggaggaaaa gaggtatctt   1320

ttaaaataga gatagttaca tattttcctc atctaggctg tgtcactatt gggtgcaagg   1380

atatcattgt tggctagatt cattttgtat aatcatgtat cctcttgtgt gctggtagag   1440

attttaatcc tgatttttcc ataaaacatg agtattaaga aataattcct ggtttggaga   1500

aactggagaa atcacccttt taaggaagaa acactggaaa tttctgctaa caccaagata   1560

tttaagagtg tacatagtag gtgctcaaca aatttattga atgaatgagt gaatggaaaa   1620

actgggagag tcaaaagtga gcagaagctc tccatttcta cttctgtcac aaaccacatt   1680

aaattgtaaa taaggccctt ctccacttga cttcaggcag cagattgtct agaagcctaa   1740

ggacagcaat ttctctgaca agacaaagta gatattttat accaggggtt ggcaaactac   1800

tgcccacggg ccgaatttgg cccagtctgt ttttgtatgg tgcaaactaa aaatgatttt   1860

tacattttta aagagttata aaagaaaaaa atatgtggtc tgtgaaatct aaaatattta   1920

ctacctggcc tgttggagga aaggtttgcc aatctctgtt ttataccatt aactatgaga   1980

ttaacaaaaa cttttacctt tgtgcagaag gttaaaaaaa aaaaaacatg gttaaggaaa   2040

aggagacatg ttacctcttc atacactcct ataactgtgg cattgcaaaa aataaaaata   2100

accaccttta aaaaaataaa tcttatttaa attgctgtaa aaaaaaa                 2147


<210>  770
<211>  2194
<212>  DNA
<213>  Human

<400>  770
gggtctcgcc ggctcgccgc gctccccacc ttgcctgcgc ccgcccggag ccagcggttc     60

tccaagcacc cagcatcctg ctagacgcgc cgcgcaccga cggaggggac atgggcagag    120

caatggtggc caggctcggg ctggggctgc tgctgctggc actgctccta cccacgcaga    180

tttattccag tgaaacaaca actggaactt caagtaactc ctcccagagt acttccaact    240

ctgggttggc cccaaatcca actaatgcca ccaccaaggc ggctggtggt gccctgcagt    300

caacagccag tctcttcgtg gtctcactct ctcttctgca tctctactct taagagactc    360

aggccaagaa acgtcttcta aatttcccca tcttctaaac ccaatccaaa tggcgtctgg    420

aagtccaatg tggcaaggaa aaacaggtct tcatcgaatc tactaattcc acacctttta    480

ttgacacaga aaatgttgag aatcccaaat ttgattgatt tgaagaacat gtgagaggtt    540

tgactagatg atggatgcca atattaaatc tgctggagtt tcatgtacaa gatgaaggag    600

aggcaacatc caaaatagtt aagacatgat ttccttgaat gtggcttgag aaatatggac    660

acttaatact accttgaaaa taagaataga aataaaggat gggattgtgg aatggagatt    720

cagttttcat ttggttcatt aattctataa ggccataaaa caggtaatat aaaaagcttc    780

catgattcta tttatatgta catgagaagg aacttccagg tgttactgta attcctcaac    840

gtattgtttc gacagcacta atttaatgcc gatatactct agatgaagtt ttacattgtt    900

gagctattgc tgttctcttg ggaactgaac tcactttcct cctgaggctt tggatttgac    960

attgcatttg accttttatg tagtaattga catgtgccag ggcaatgatg aatgagaatc   1020

tacccccaga tccaagcatc ctgagcaact cttgattatc catattgagt caaatggtag   1080

gcatttccta tcacctgttt ccattcaaca agagcactac attcatttag ctaaacggat   1140

tccaaagagt agaattgcat tgaccacgac taatttcaaa atgcttttta ttattattat   1200

tttttagaca gtctcacttt gtcgcccagg ccggagtgca gtggtgcgat ctcagatcag   1260

tgtaccattt gcctcccggg ctcaagcgat tctcctgcct cagcctccca agtagctggg   1320

attacaggca cctgccacca tgcccggcta atttttgtaa ttttagtaga gacagggttt   1380

caccatgttg cccaggctgg tttcgaactc ctgacctcag gtgatccacc cgcctcggcc   1440

tcccaaagtg ctgggattac aggcttgagc ccccgcgccc agccatcaaa atgcttttta   1500

tttctgcata tgttgaatac tttttacaat ttaaaaaaat gatctgtttt gaaggcaaaa   1560

ttgcaaatct tgaaattaag aaggcaaaaa tgtaaaggag tcaaaactat aaatcaagta   1620

tttgggaagt gaagactgga agctaatttg cattaaattc acaaactttt atactctttc   1680

tgtatataca ttttttttct ttaaaaaaca actatggatc agaatagcca catttagaac   1740

actttttgtt atcagtcaat atttttagat agttagaacc tggtcctaag cctaaaagtg   1800

ggcttgattc tgcagtaaat cttttacaac tgcctcgaca cacataaacc tttttaaaaa   1860

tagacactcc ccgaagtctt ttgttcgcat ggtcacacac tgatgcttag atgttccagt   1920

aatctaatat ggccacagta gtcttgatga ccaaagtcct ttttttccat ctttagaaaa   1980

ctacatggga acaaacagat cgaacagttt tgaagctact gtgtgtgtga atgaacactc   2040

ttgctttatt ccagaatgct gtacatctat tttggattgt atattgtgtt tgtgtattta   2100

cgctttgatt catagtaact tcttatggaa ttgatttgca ttgaacacaa actgtaaata   2160

aaaagaaatg gctgaaagag caaaaaaaaa aaaa                               2194


<210>  771
<211>  1693
<212>  DNA
<213>  Human

<400>  771
ggcggggttt cccgcgctcg gcggaagcgg aaggggcggg gctccgcgct cctagtctcc     60

actgctgccg ccgtcgccgc cacccgagcc ggagcgggct gggccgccaa ggcaagatgg    120

tggactacag cgtgtgggac cacattgagg tgtctgatga tgaagacgag acgcacccca    180

acatcgacac ggccagtctc ttccgctggc ggcatcaggc ccgggtggaa cgcatggagc    240

agttccagaa ggagaaggag gaactggaca ggggctgccg cgagtgcaag cgcaaggtgg    300

ccgagtgcca gaggaaactg aaggagctgg aggtggccga gggcggcaag gcagagctgg    360

agcgcctgca ggccgaggca cagcagctgc gcaaggagga gcggagctgg gagcagaagc    420

tggaggagat gcgcaagaag gagaagagca tgccctggaa cgtggacacg ctcagcaaag    480

acggcttcag caagagcatg gtaaatacca agcccgagaa gacggaggag gactcagagg    540

aggtgaggga gcagaaacac aagaccttcg tggaaaaata cgagaaacag atcaagcact    600

ttggcatgct tcgccgctgg gatgacagcc aaaagtacct gtcagacaac gtccacctgg    660

tgtgcgagga gacagccaat tacctggtca tttggtgcat tgacctagag gtggaggaga    720

aatgtgcact catggagcag gtggcccacc agacaatcgt catgcaattt atcctggagc    780

tggccaagag cctaaaggtg gacccccggg cctgcttccg gcagttcttc actaagatta    840

agacagccga tcgccagtac atggagggct tcaacgacga gctggaagcc ttcaaggagc    900

gtgtgcgggg ccgtgccaag ctgcgcatcg agaaggccat gaaggagtac gaggaggagg    960

agcgcaagaa gcggctcggc cccggcggcc tggaccccgt cgaggtctac gagtccctcc   1020

ctgaggaact ccagaagtgc ttcgatgtga aggacgtgca gatgctgcag gacgccatca   1080

gcaagatgga ccccaccgac gcaaagtacc acatgcagcg ctgcattgac tctggcctct   1140

gggtccccaa ctctaaggcc agcgaggcca aggagggaga ggaggcaggt cctggggacc   1200

cattactgga agctgttccc aagacgggcg atgagaagga tgtcagtgtg tgacctgccc   1260

cagctaccac cgccacctgc ttccaggccc ctatgtgccc cttttcagaa aacagataga   1320

tgccatctcg cccgctcctg acttcctcta cttgcgctgc tcggcccagc ctggggggcc   1380

cgcccagccc tccctggcct ctccactgtc tccactctcc agcgcccatt caagtctctg   1440

ctttgagtca aggggcttca ctgcctgcag ccccccatca gcattatgcc aaaggcccgg   1500

gggtccgggg aagggcagag gtcaccaggc tggtctacca ggtagttggg gagggtcccc   1560

agccaagggg ccggctctcg tcactgggct ctgttttcac tgttcgtctg ctgtctgtgt   1620

cttctatttg gcaaacagca atgatcttcc aataaaagat ttcagatgct caaaaaaaaa   1680

aaaaaaaaaa aaa                                                      1693


<210>  772
<211>  3341
<212>  DNA
<213>  Human

<400>  772
tgagtttcac gcgcgtatgc tttgcccgcc atggccgcag tcaaggagcc tttggagttc     60

catgccaagc ggccttggcg ccccgaggag gcagtagaag atccggacga ggaggatgag    120

gataatacta gtgaagccga gaatgggttc tccctggagg aagtgttacg gctcggaggc    180

accaagcaag attaccttat gctggctact ttggatgaga atgaggaagt gatagatgga    240

ggcaaaaaag gagcaatcga tgaccttcag caaggtgaat tggaagcatt tattcaaaat    300

cttaatttgg cgaagtatac aaaagcttcc ttagttgaag aagatgaacc agctgaaaaa    360

gaaaattcca gcaaaaaaga agtaaaaata cctaaaataa ataataaaaa tacagcagaa    420

agtcaaagga catcagttaa taaggtgaaa aataagaata ggccagaacc acattctgat    480

gagaatggca gtaccacacc gaaagtaaag aaagataaac agaacatctt tgaatttttt    540

gagagacaga ctttgttact taggcctgga ggcaaatggt atgatctgga gtacagcaat    600

gaatattctt tgaaacccca gcctcaggat gttgtatcta agtacaaaac ccttgctcag    660

aagctgtatc agcatgaaat caacttattc aaaagtaaga cgaatagtca aaagggagcc    720

tcttctacct ggatgaaggc aattgtgtca tcggggacac taggtgacag gatggcagcc    780

atgattcttc ttattcagga tgatgccgtt cacacacttc agtttgtaga aactcttgtg    840

aaccttgtta aaaagaaggg cagcaaacag cagtgcctta tggccttgga tactttcaaa    900

gagttgctta tcacagacct tttgccagac aatcggaagc tgaggatttt cagccagcgt    960

ccttttgaca aactggaaca gttgtccagt ggcaacaagg actcaagaga tagaagactg   1020

atattatggt attttgaaca ccagctgaaa cacttagtgg ctgaatttgt gcaggtctta   1080

gaaactttaa gtcatgatac attagtaacc actaaaactc gagcccttac cgtggctcat   1140

gagctgcttt gtaacaagcc tgaggaagaa aaggctcttc ttgtgcaagt ggtaaataaa   1200

ctgggagatc ctcagaacag aattgccaca aaagcatccc atctgttaga gacattactt   1260

tgtaaacatc ccaatatgaa aggagttgtg tctggtgaag tagaaaggct actcttccgc   1320

tcaaatatca gctccaaagc tcaatattat gcaatttgct ttttaaatca aatggctctg   1380

tcccatgaag aaagtgaatt ggctaacaaa ttaataactg tttacttttg cttttttcgg   1440

acttgtgtca aaaaaaaaga tgttgaatca aaaatgctta gcgccctttt aacaggtgtg   1500

aatagggcat acccttattc ccagactggt gatgacaaag taagggagca gattgacaca   1560

ctgtttaaag tgttgcatat tgtgaatttt aataccagtg tccaggcttt aatgttgctt   1620

ttccaagtaa tgaattctca gcagacaata tcggatcgat attacacagc attatacagg   1680

aagatgttgg atccagggtt gatgacgtgt tccaagcaag ctatgtttct taaccttgtc   1740

tacaaatctc tgaaagctga cattgtgttg cgccgggtga aggcttttgt gaagaggtta   1800

cttcaagtta cttgtcaaca gatgccacca tttatatgtg gagctttata tcttgtgtct   1860

gagatcctta aagcaaaacc aggtttaaga agccaactag atgatcatcc ggagtctgat   1920

gatgaagaaa attttattga tgcaaatgat gatgaagaca tggaaaaatt cactgatgca   1980

gacaaagaaa cagagatagt gaaaaaactt gagacagagg aaacagttcc tgaaactgat   2040

gtagaaacca aaaaaccaga ggttgcttcc tgggtgcact ttgataattt gaaaggtggg   2100

aaacagttaa ataaatacga tccattcagt agaaaccctc tgttctgtgg agctgaaaat   2160

acaagtcttt gggaactcaa aaagttatct gtgcattttc atccctccgt ggcccttttt   2220

gcaaagacca tccttcaggg aaactatatt cagtattcag gggacccact gcaggatttc   2280

actctaatga gatttttgga tcgatttgta taccgaaatc caaagcccca taaaggcaaa   2340

gaaaacacag atagtgttgt gatgcagccg aaaagaaaac attttattaa ggatattcgt   2400

catcttcctg tgaacagtaa ggagttcctt gcaaaagaag aaagccaaat accagtggat   2460

gaagtgtttt tccacaggta ttataaaaaa gttgctgtta aagagaaaca aaaacgggat   2520

gcagatgaag aaagtataga agacgtggat gatgaagaat ttgaagagct gattgacaca   2580

tttgaagatg ataactgttt cagctctgga aaggatgata tggattttgc tggaaacgtg   2640

aaaaagagaa caaaaggagc taaggataac acattagatg aagattcaga aggtagtgat   2700

gatgaacttg gtaacctgga tgacgatgaa gtttctttag gaagtatgga tgatgaagaa   2760

tttgctgaag ttgatgaaga tggaggaaca ttcatggatg tgttagatga tgaaagtgag   2820

agcgttccag aacttgaagt ccactccaaa gtcagtacta agaaaagcaa gagaaaaggt   2880

acagatgatt ttgactttgc tggctcattt caagggccaa gaaaaaagaa aagaaactta   2940

aatgattcca gcctatttgt atctgctgaa gagtttggcc atctattgga tgaaaatatg   3000

ggatccaagt ttgataacat tggcatgaat gccatggcta acaaagataa tgcaagtctc   3060

aaacagctta gatgggaggc tgaacgtgat gactggctac acaacagaga tgcaaaaagt   3120

atcatcaaga aaaagaaaca ttttaaaaag aagaggatta aaaccactca aaaaactaaa   3180

aaacaaagga aatgagttat taatgtaaat tatagattaa aattctactt acatctaatt   3240

tttgctgttc aaccatgttt tttgatctag ctctctgatt ccatacattc cagacttctc   3300

agtggatttg taataaacta taaataaaaa aaaaaaaaaa a                       3341


<210>  773
<211>  2070
<212>  DNA
<213>  Human

<400>  773
ctgcaggctc tctccgagag caccaagtcc ttttgctctc catccccgga agacccggct     60

gaaaatccgg aaaaagaatc gggaaacgcc aggaggcata ttgcgcttgc gcacggaggg    120

gccggaagtc gaggcgggag tgactctgct tccgtttctg gttttgctct agtgtttggg    180

tttcttcgcg gctgctcaag atgaaccgac tcttcgggaa agcgaaaccc aaggctccgc    240

cgcccagcct gactgactgc attggcacgg tggacagtag agcagaatcc attgacaaga    300

agatttctcg attggatgct gagctagtga agtataagga tcagatcaag aagatgagag    360

agggtcctgc aaagaatatg gtcaagcaga aagccttgcg agttttaaag caaaagagga    420

tgtatgagca gcagcgggac aatcttgccc aacagtcatt caacatggaa caagccaatt    480

ataccatcca gtctttgaag gacaccaaga ccacggttga tgctatgaaa ctgggagtaa    540

aggaaatgaa gaaggcatac aagcaagtga agatcgacca gattgaggat ttacaagacc    600

agctagagga tatgatggaa gatgcaaatg aaatccaaga agcactgagt cgcagttatg    660

gcaccccaga actggatgaa gatgatttag aagcagagtt ggatgcacta ggtgatgagc    720

ttctggctga tgaagacagt tcttatttgg atgaggcagc atctgcacct gcaattccag    780

aaggtgttcc cactgataca aaaaacaagg atggagttct ggtggatgaa tttggattgc    840

cacagatccc tgcttcatag atttgcatca ttcaagcata tcttgtaaaa caaacacata    900

ttatgggact aggaaatatt tatctttcca aatttgccat aacagattta ggtttctttc    960

ctttctttga aggaaagttt aattacattg ctcttttatt ttttccatta agagactcat   1020

tgcttgggaa atgctttctt cgtactaaaa tttgattcct ttttttctta tgaaaaacga   1080

actcagttta aaagtatttt tagctcgtat gacttgtttt cattcattaa taataatttg   1140

aaataaaact aaggaaatgg aatcttaaaa gtctatgaca gtgtaactct acagtctcaa   1200

aatgacctga taaattgata agacaaagat gagattattg gggctgttca tattatgatt   1260

cagaatcatt ttctattgtg gtattatagg ttggttaaag tgatggcctt tttgatgggt   1320

tttgttgtgt cttgtgaaca agtcgttact gtgtccatta ttggaatgga attatcacta   1380

ctgtatcatg agtgggtatt ttgattctat ggttccctca gtattacatc ttgacttgta   1440

atcaattatg aatatttctt gatatttaat gtataggaca tttatttata ctcaataaat   1500

atttttcaaa aggatataat tttaataata tcacttcagc ttaaaacctc tactgcggaa   1560

accaaattta atagaatttt aatgtcattt cagcctataa ctccactaca gaaaccaaat   1620

taaccagtag cattgtgagg aaagagcaag gaacaatctg ggcttgggcc ctgggtctac   1680

catttactaa ctactgagta gtctattcaa cctctctaac cttctgtttc cttattagta   1740

aaatcatgct taactcacag agcttttgtg aggaataatt gaggtaatgg tcataagtac   1800

cttgttaact gcaaggggct attcttatat gagggattgt taacaataaa aaagaaactg   1860

cttcattctt ttcttggaag gtgcctggag tactacagca agttcaaact cctgcccaat   1920

ttcagggtct ttaatgatcc tgtcctccct tcctcattca acttgttgcc aacagcatgg   1980

cccctccagc ctagctgggt gcctcacagt gctatgtgca cctgactctc atgtgtctgc   2040

agatcaaacc aataaacatt taggaacacc                                    2070


<210>  774
<211>  3096
<212>  DNA
<213>  Human

<400>  774
gcagtgcgcg acggcggcgg cggcgcggga ggttcggagc gggagctcgg gctcgcggac     60

ggtatggagg actacgagca ggagctgtgc ggcgtcgagg atgatttcca caaccagttc    120

gcggccgagc tggaggtgct ggcagagctg gaaggggcgt cgactccgtc gccctccggg    180

gtccccctgt tcaccgcggg ccgacccccg cggacgttcg aggaggccct tgccagaggg    240

gacgcggcct ccagtcccgc cccagccgca tctgtgggca gcagccaggg cggcgccagg    300

aagaggcagg tggacgccga cctgcagccg gccgggtccc tgccccacgc ccccaggatc    360

aaacggccta ggctgcaggt ggtcaagagg ctgaacttca ggtcggagga gatggaggag    420

ccgccccctc ccgactcctc gccgacggac atcaccccgc cgccgagccc tgaggacctc    480

gcagagcttt ggggccacgg agtctcagaa gctgctgccg acgtgggtct cacacgggcc    540

tcaccagctg cccgcaatcc cgtcctgagg cggcccccca tcttggagga ctacgtccac    600

gtgacatcca cggagggcgt ccgggcttat ctggtgctgc gtgctgaccc catggccccg    660

ggggtgcagg gctctctcct ccacgtccca tggcgaggcg gtggccagct ggacctgctg    720

ggtgtgtcct tagcctccct gaagaagcag gtcgacggcg agcggcggga gcggctgctt    780

caggaggccc agaagctttc agacaccctg cacagtctca ggtcggggga ggaggaggca    840

gcccagccct tgggggcccc tgaggaggag ccgactgacg gtcaagacgc ctccagtcac    900

tgcctctggg tggatgagtt tgcaccccgc cactacacgg agctgctcag tgatgacttc    960

accaaccgct gcctgctcaa gtggctgaag ttgtgggacc tggtggtgtt tggccacgag   1020

aggccttccc ggaagcccag gcccagtgtt gagccggccc gggtcagcaa ggaggccaca   1080

gccccaggca agtggaagag ccacgaacag gtgctggagg agatgctgga ggctgggctg   1140

gacccgagcc agcgaccgaa gcagaaggtg gcactgctct gtgggccccc ggggctgggg   1200

aagaccaccc tggcacacgt gattgcgcgt cacgcggggt actctgtggt ggagatgaac   1260

gccagtgacg accgtagccc ggaggtcttc cgcacacgca tcgaggcggc cacccagatg   1320

gagtcggtgc tgggtgctgg cgggaagccc aactgcctgg tcatcgatga gatcgacggg   1380

gcccccgtgg ccgccatcaa cgtcctcctg agcatcctga accgcaaggg gccacaggag   1440

gtggggccac agggcccggc tgtgccttcg ggaggcggcc gacggcgccg ggcagagggg   1500

gggctcctca tgaggcccat tatctgcatt tgcaatgacc agttcgcacc gtccctgcgg   1560

cagctgaagc agcaggcctt cctgctccac ttcccgccga ctctgccctc gaggctggtg   1620

cagcggctcc aggaggtctc cctgcggcag ggcatgaggg ccgacccagg ggtgctggcc   1680

gccctctgtg agaaaactga caatgacatc cgggcctgca tcaacaccct gcagttcctg   1740

tacagccggg gccagcggga gctgagcgtg cgggacgtgc aggccacacg cgtgggcctc   1800

aaggaccagc gcagagggct cttctcggtg tggcaggagg tcttccagct gcctcgagcc   1860

cagaggcgcc gtgtgggcca ggaccccgcc ctgcctgctg acacactcct gctgggtgac   1920

ggggacgcgg gctccctcac ctccgcctca cagcgattct accgtgtcct gcatgccgct   1980

gcctctgcgg gcgagcacga gaaggtggtc cagggcttgt ttgacaactt cctgcgtctg   2040

cggctgcgag actccagcct gggtgctgtg tgtgtggccc tcgactggct ggccttcgat   2100

gacctgctgg cgggggctgc tcatcacagc cagagcttcc agctgctgcg ctacccaccc   2160

ttcctgcccg tggccttcca tgtgctgttt gcttccagcc acacacccag gatcaccttc   2220

cccagcagcc agcaggaggc ccagaaccgg atgagccaga tgaggaacct gatccagacg   2280

ctggtgtccg gcatcgcgcc agccacgcgc agccgggcca cgccccaggc cctgctcctc   2340

gatgccctct gcctgctcct ggacattctt gcacccaagc tccgccccgt gagcacacag   2400

ctgtacagca cccgtgaaaa gcaacagctg gccagcctgg tgggcacgat gctcgcttac   2460

agcctgacct accgccagga gcgcacgccc gatggccagt acatctacag gctggagccg   2520

aacgtggagg aactctgccg cttccctgag ctgcctgccc gcaagcccct cacctaccag   2580

acgaagcagc tcatcgcccg cgagatcgag gtggagaaga tgcggcgggc ggaggcttct   2640

gcccgggtag agaacagccc ccaggtggat gggagccccc cagggctcga gggtctgctg   2700

gggggcattg gggagaaagg ggtgcaccga cctgccccac gcaaccatga gcagcggctg   2760

gagcacatca tgaggcgagc ggcccgggag gaacagcctg agaaggactt ctttggacgt   2820

gtggtcgtca ggagcacagc agtcccgagt gcaggggaca cggccccgga gcaggactca   2880

gtggagcggc gcatgggcac agcggtgggc aggagcgagg tctggttccg cttcaacgag   2940

ggtgtctcca acgccgtgcg gcgcagcctg tacatcaggg acttgctcta gttctctgag   3000

ccgcggacat gccctcgcat tgcttcccgc agagtgcaga gacaggaagc tggagatgtc   3060

tttataaagt cacaccttta cagactgtaa aaaaaa                             3096


<210>  775
<211>  2956
<212>  DNA
<213>  Human

<400>  775
gacagggccg cggacgcccg ggcagccacg gcggcggggc cgcggcgggc gccggctcag     60

cccgcccctt tctcccgccg cctccccgcc ccgccccgcg ccgcgccggc cgctgtcagc    120

tccctcagcg tccggccgag gcgcggtgta tgctgagccg ctgccgcagc gggctgctcc    180

acgtcctggg ccttagcttc ctgctgcaga cccgccggcc gattctcctc tgctctccac    240

gtctcatgaa gccgctggtc gtgttcgtcc tcggcggccc cggcgccggc aaggggaccc    300

agtgcgcccg catcgtcgag aaatatggct acacacacct ttctgcagga gagctgcttc    360

gtgatgaaag gaagaaccca gattcacagt atggtgaact tattgaaaag tacattaaag    420

aaggaaagat tgtaccagtt gagataacca tcagtttatt aaagagggaa atggatcaga    480

caatggctgc caatgctcag aagaataaat tcttgattga tgggtttcca agaaatcaag    540

acaaccttca aggatggaac aagaccatgg atgggaaggc agatgtatct ttcgttctct    600

tttttgactg taataatgag atttgtattg aacgatgtct tgagagggga aagagtagtg    660

gtaggagtga tgacaacaga gagagcttgg aaaagagaat tcagacctac cttcagtcaa    720

caaagccaat tattgactta tatgaagaaa tggggaaagt caagaaaata gatgcttcta    780

aatctgttga tgaagttttt gatgaagttg tgcagatttt tgacaaggaa ggctaattct    840

aaacctgaag gcatccttga aatcatgctt gaatattgct ttgatagctg ctatcatgac    900

ccctttttaa ggcaattcta atctttcata actacatctc aattagtggc tggaaagtac    960

atggtaaaac aaagtaaatt tttttatgtt cttttttttg gtcacaggag tagacagtga   1020

attcaggttt aacttcacct tagttatggt gctcaccaaa cgaagggtat cagctatttt   1080

ttttaaaatt caaaaagaat atccctttta tagtttgtgc cttctgtgag caaaactttt   1140

tagtacgcgt atatatccct ctagtaatca caacatttta ggatttaggg atacccgctt   1200

cctctttttc ttgcaagttt taaatttcca accttaagtg aatttgtgga ccaaatttca   1260

aaggaacttt ttgtgtagtc agttcttgca caatgtgttt ggtaaacaaa ctcaaaatgg   1320

attcttagga gcattttagt gtttattaaa taactgacca tttgctgtag aaagatgaga   1380

aaacttaagc tttgttttac tacaacttgt acaaagttgt atgacagggc atattctttg   1440

cttccaagat ttgggttggg ggcactaggg gttcagagcc tggcagaatt gtcagcttta   1500

gtctgacata atctaagggt atggggcaag gatcacatct aatgcttgtg ttccttatac   1560

tctattatat agtgttattc atgattcagc tgatcttaac aaaattcgta gcagtggaac   1620

cttgaaatgc atgtggctag atttatgcta aaatgattct cagttagcat tttagtaaca   1680

cttcaaaggt ttttttttgt ttgttttcta gacttaataa aagcttagga ttaattagaa   1740

gaagcaatct agttaaattt cccatttgta ttttattttc ttgaatactt ttttcatagt   1800

tatttgttta aaaagattta aaaatcattg cactttggtc agaaaaataa taaatatatc   1860

ttataaatgt ttgattccct tccttgctat ttttattcag tagatttttg tttggcatca   1920

tgttgaagca ccgaaagata aatgattttt aaaaggctat agagtccaaa ggaatattct   1980

tttacaccaa ttcttccttt aaaaatctct gaggaatttg ttttcgcctt actttttttt   2040

cttctgtcac aatgctaagt ggtatccgag gttcttaata tgagatttaa aatcttaaaa   2100

tgtttcttat tttcagcact tacatcattt ggtacacagg gtcaaatagg gcaaataatt   2160

ttgtctttgt ataatagatt tgatatttaa agtcactgga aataggacaa gttaatggat   2220

gtttttatat tttaatagaa tcatttattt ctatgtgtta tgaaattcac ttaatgataa   2280

atttttcaac atacttgcca ttagaaaaca aagtattgct aagtactata acatattggc   2340

cactaaaatt catattgaga ttatcttggt ttcttggaag agataggaat gagttcttat   2400

ctagtgttgc aggccagcaa atacagaggt ggtttaatca aacagctcta gtatgaagca   2460

agagtaaaga ctaaggtttc gagagcattc ctactcacat aagtgaagaa atctgtcaga   2520

taggaatcta aatatttata gtgagattgt gaaagcaacc ttaaagtttt gaagaagact   2580

gatgagacta ggtgctttgc ttcctttcat caggtatctt tctgtggcat ttgagaacag   2640

aaaccaagaa acatggtaat tactaaatta tgaggctttg ctttttgttt gcttttaagt   2700

agaaaaacat gttggcaaca ttgagttttg gagttgattg agataatatg acttaactag   2760

ttttgtcatt ccatttgtta aagatacagt caccaagaat gttttgagtt ttttgaaaga   2820

ccccaattta agccttgctt atttttaaat tatttccatt cagtgatgtt ggatgtatat   2880

cagttattta gtaaataatc tcaataaatt ttgtgctgtg gcctttgcta aaaaaaaaaa   2940

aaaaaaaaaa aaaaaa                                                   2956


<210>  776
<211>  1977
<212>  DNA
<213>  Human

<400>  776
ggggtgatca tggacgcttg acaacctgcg ggcaggcgcc gggaggccga gccagcgact     60

aagaggaccg agaggtggcg tggacagatt tcaaggccag agaatggcag gggaacagaa    120

accctcaagt aatctcctgg agcagtttat tttactagcc aaaggtacca gtggctcagc    180

cctcactgct ctcataagcc aggtcttaga ggctcccgga gtgtatgtct ttggagaact    240

tctggagctg gccaacgtgc aggagcttgc ggaaggagct aatgctgctt atttgcagtt    300

gttgaacctg tttgcctatg ggacataccc agattacata gccaacaagg agagcctgcc    360

agaactgagc acagctcagc agaacaagct gaagcatctt accatcgtga gcttggcatc    420

aagaatgaag tgtatcccct actccgtgtt gctgaaagac ctggagatgc ggaatctccg    480

ggaactagaa gaccttatca ttgaggctgt ctacactgac atcatccagg gcaagctgga    540

ccagcgaaac cagctgctgg aagtggattt ctgcattggc cgtgacatcc gaaagaagga    600

tatcaataat attgtcaaga ccctgcatga atggtgtgat ggctgtgaag cagttctact    660

gggcatcgag cagcaagttc tgagagccaa ccagtacaaa gagaaccaca accgaactca    720

gcagcaggta gaagcagagg ttaccaacat caagaagaca ctcaaagcca ccgcatcctc    780

ctcggctcag gagatggagc agcagctggc tgaacgggag tgtccccctc acgctgagca    840

gaggcagccc accaagaaga tgtccaaagt gaaaggtctg gtctccagcc gccactaggg    900

ccggctgggg cagctggcac tcaccaggcc tgggtcaggt ggggagggga caccaagggc    960

ccatttcctc ccctctctac ctgcagtgag ttccagacct gcccgtcccc tcaccagcgc   1020

ctccccaccc tgttggtact gttccagaaa aactgttact ccccctcacc cactccctcc   1080

ttccccagtt gttcccttca gactcagggg ctccaccaat gccatcccaa aacagggtca   1140

gacactgctc agcttccctc caggaggttc ttgtctctgt gtaagggctt gtctccctcc   1200

cagtttttct tttgctccac gtcattttgt caggctggtt ataagccgga ggcagcttta   1260

accagccccc agggatgatt gtgaaggagg cccctcccct tgtgaggagg gggcactcct   1320

ctccagcccc tggtaccaca gtcctcacga tggtgcagtg atttctagcc aggcgtcaag   1380

atgcgctgct ttccctctcc tgcctcattc cttgttggca gctccagttc aggccgtgga   1440

gggacgtgat gctgggctgt gtttactaaa cccacgggtt ttcagcctct taagcccagc   1500

tccgatctcc aattagttga gagcgctggg ttgactaacc tctggtatct gagcacagac   1560

agagggtgct gtgggtctgc tgggtggcag aaatggttcc ttccggcttg gcgttctctc   1620

ctggccactc ttcctgctgc ctctgactac tcagccttgt tttcggtgtg taggccccag   1680

ctgcccactg gaactgccgg ctaatgcttg ctctcccaag atctttaact cctcctggct   1740

gcacctgggt agggatggtg gcatcgatgc ccctctgtct gctgaaggac ctgttgctgc   1800

ttctgtcttt tcacccctcc ttggctgatg acccagagcc ctctgatgat ggcattctcc   1860

tggcaagaga aaaagactta actagacttc tgaacttgaa cagtttcagg ttatatttta   1920

attttttttt ttttgtacag gttctgattc taatacattt caacatgctt ttgtccc      1977


<210>  777
<211>  1597
<212>  DNA
<213>  Human

<400>  777
gaggttcgca ttttatagtc ttcggggaaa accggctgtg gagaaggaaa tagggcccgg     60

cgctgagtga gcgtggttgc gtgtcctttg cagacacttt ctggggcgag gtgacatggc    120

gagagtcttg gatcggtgga cgtagacggt agacagttcg cgtgcgtttc cttcgcctac    180

ttggcctaca tgccttctgc ccgtgaagcg atgtttcccc tcgaaaggcc gtaggctacg    240

ccgtcagaat cggtttttca gtgagttttg acccctccga cgctccgtcg cctgacagaa    300

tcgcggcgtt cttcgtaccc gcccatcctc cgcggacgcc cgctgccatg gcgactctgc    360

tgcgccctgt cctccgtcgg ctctgcgggc tcccgggcct acagcggcct gcggcagaaa    420

tgcccctccg ggctaggagc gacggcgccg gcccgctata ctcgcaccac ctccccacct    480

ccccgctgca gaaagcgctg ttggccgccg gctccgcggc gatggcgctc tataacccct    540

accgccacga catggtcgca gttctagggg agaccacagg acaccgcacc ctgaaggtcc    600

tcagggacca gatgaggagg gatccagagg gtgcccagat cctgcaggag cgtccccgga    660

tttcgacatc caccctcgac ctgggcaagc tccagagcct gccggaaggc tccctcggtc    720

gcgagtatct ccgtttcctg gatgtgaaca gggtctcccc agacacccga gcacccaccc    780

gcttcgtgga tgatgaggag ctagcgtatg tgattcagcg gtaccgggag gtgcacgaca    840

tgcttcacac cctgctgggg atgcccacca acatcctggg ggagatcgtg gtgaaatggt    900

ttgaggctgt ccagactggc ctgcccatgt gcatcctggg tgcattcttt ggaccgatcc    960

gacttggcgc tcagagcctg caagtgctgg tctcggagtt gatcccatgg gccgttcaga   1020

acgggcgcag agccccatgt gtcctcaacc tgtactatga gcggcgctgg gagcagtccc   1080

tgagggctct gcgggaggag ctgggcatta cagcaccacc catgcacgtc cagggcttgg   1140

cctgagctcc tgagccagcg gggcctggcc tacctccccc atcccctgct tcccttggag   1200

gcagagggct cccttgacta cctttgttcc tcttctttga acactgaccc ttggacaaca   1260

tttatcataa tttgtcataa ccactgctga gtggccttga ggacgaaccc cgcagggagc   1320

aagcagtaca gtggcattcc cagggggacc agcagctacc caaggagaac catgcatgaa   1380

cagtatcagt cgtctgggct catgctggga tgtcgcagtg ctcctgttgc aactcctccc   1440

agccagccag gtttgctggg ggccaggctg ggtgtcctca caggagtgag ggctacaccc   1500

aattccaaaa gcctgagaag agagaagtgg agggggaggc gagtgtgtga ataaaggctc   1560

ccatcaggtc aaaaaaaaaa aaaaaaaaaa aaaaaaa                            1597


<210>  778
<211>  2545
<212>  DNA
<213>  Human

<400>  778
gaggggctga ggtaccgccc gcgcgagcac acacagacac acacacacac acacacacac     60

acacacacac acatcttcca gacccatccc ctgcctgcca gctccacgag ccagagagag    120

acagagcgcg gacgccgcag gaggcagtgc ctggacccca gctgcccagg agagacggag    180

cccgtggctg gtgaggccgc agagcagggc caggccgggc cctgcccgca aggacgacca    240

aacccctcac cggcccctgg gccccagagc ccaccaggct ctcctgctgg ccccaccatg    300

acttcagagt cgacgtcacc cccagttgtg cccccgctcc actcccccaa gtccccagtc    360

tggcccacct tccccttcca cagggagggc agcagggtct gggagcgggg tggtgtccca    420

cctcgggacc tacccagccc tctgcccacc aagcggacca ggacctattc agcgacagcc    480

cgggcctcag ctggccccgt gttcaagggc gtctgtaagc agttctcacg ctcacagggc    540

catggcttca tcacccccga gaacgggtcc gaggacatct tcgtacatgt gtctgacatc    600

gagggggagt acgtgccagt ggagggcgac gaggtgacct acaagatgtg ccctatccct    660

cccaagaacc agaagttcca ggccgtggag gtggtgctca ctcagctggc cccccacact    720

ccccacgaga cgtggtctgg ccaggtcgtg ggctcctagg ctgagtggtt cacaggccag    780

ctggccgggg gttggggagc cacacagggt gaacgggcag cagccggctc catgccccac    840

tgccctggct gatgagtcct tcggtggcct cagtgtgcac gtctgtctgt ccgtctgtgc    900

ttgtggctat gagcgtgtgc ctccacccac cccacgaccc gtgactactg tgcaagctgg    960

ccaggaggta ggtggagggc aaggccacca gacctggctt cgcgctgtcc actgcctctc   1020

tcctcccctc cctgccgcag acacgcagga cccgctcgcc ctcctgctta cccgtcccca   1080

cggtgactga gctgcgagag cctgcgctgg gctcactccc tggcctccgc ccctgagctg   1140

tcccgtgtca gtccctggcc cggagccagg ctctctgtgc tacttacatc tccctccctt   1200

ggctgaggtc ccccgccaca gcctggaccc ttccctcaga agcctggccg atgggtgctt   1260

ttggggagcc tctcagcctc tggcagggga ggaggactga cacggaggca cacaggcctc   1320

tcactgccga ggccagcctt ccttcctgct ctgctctctc agtgccatgg agaggcagga   1380

agaggggcct gagggcggaa ggggtttggg gctcccattt cgccggccag tccctcctcc   1440

tcagcctggc agtggcgctg ggctccttcc cctgggctgt actgagccga gcccaggggt   1500

ttgcagaggg tgggggtcca tctctccagc ttggctgcag acctccttta ccctgactca   1560

caagccccac tgatgctctg ggccatgccc ggctgacggc tgctgtggat gccgcgaggg   1620

acggacacac gtccggggca cccacgagga gggcccccag cctgggagac tggccctgcg   1680

gcctccacgt caaactctct tcccaaagcc ctaacagacc agtggccgag gtgtggctct   1740

tattgcatcc atccctgaag atgtgtggct gttgctgtca cctggagtcc ttttggggcc   1800

aagatgtgtg tgcacccggg gtcgtggcca ttcactccca ggcaggggtg agggtggcct   1860

ggcccaggag gccaggaagg agggccctgt ctgcctccac ctctgggtgc accccctgcc   1920

taccaccctc ccttctagag agcacatcgc ctgaccgggg agaagtgggg ccgtggttcg   1980

agggagggct ggccaggggt gggaccctta tgagactcag tctgtgagta aaactggggg   2040

ctcaaatgcc caggatgagg ggatcagtga ctgtctagga ggatcccttg ccttgtaggt   2100

gccccaagac cgcagggtag aaatcagccg ggatgcctgc atcccacccc cggccccagg   2160

gcccaccaca taaaatctgg gagcccagag ctgctgaggt gtggtcagct cccctaaaat   2220

gggcacggcc cagcctgtcc catgaggaat aaaggcccct ggcccccttg agagagggct   2280

tgttggtgag ggctgactcc tgggggcccc caaggctccc ctcctgtggg gaggccacct   2340

tttaaggcac cactagcagt caggatatgg tggcatcagc cctggggcct cctgggtggc   2400

aggggggcag cagctctcct ccccactcac aggccctgca gtgctcattt ggaattcctc   2460

ccaagacccc tggccaccca gaccccccat tcttcctaac actggcaata aaccctcaac   2520

tgtgacccac aaaaaaaaaa aaaaa                                         2545


<210>  779
<211>  2025
<212>  DNA
<213>  Human

<400>  779
gttctgcgca tgcgccgaag gggcgtggcg gtcgcacctg cgcgagttgg gggaaggagg     60

aggggcgagg tgacgcaggc gtaataatag agaaggtgcc agaaagatcc aaaacaagtg    120

gctgcggccg tcgcccagga gtcatcggac gccagaatct ggccgggttc tgagcttgtt    180

ccgcctccct cccccgggaa tggcgctatc cgggtcgacc ccggccccgt gctgggagga    240

ggatgagtgc ctggactact acgggatgct gtcgcttcac cgtatgttcg aggtggtggg    300

cgggcaactg accgagtgcg agctggagct cctggccttt ctgctggatg aggctcctgg    360

cgccgccgga ggcttagccc gggcccgcag cggcctagag ctcctgctgg agctggagcg    420

ccgcgggcag tgcgacgaga gcaacctgcg gctgctgggg caactcctgc gcgtgctggc    480

ccgccacgac ctgctgccgc acctggcgcg caagcggcgc cggccagtgt ctccagaacg    540

ctatagctat ggcacctcca gctcttcaaa gaggacagag ggtagctgcc gtcgccgtcg    600

gcagtcaagc agttctgcaa attctcagca gggtcagtgg gagacaggct cccccccaac    660

caagcggcag cggcggagtc ggggccggcc cagtggtggt gccagacggc ggcggagagg    720

ggccccagcc gcaccccagc agcagtcaga gcccgccaga ccttcctctg aaggcaaagt    780

gacctgtgac atccggctcc gggttcgagc agagtactgc gagcatgggc cagccttgga    840

gcagggcgtg gcatcccggc ggccccaggc gctggcgcgg cagctggacg tgtttgggca    900

ggccaccgca gtgctgcgct caagggacct gggctctgtg gtttgtgaca tcaagttctc    960

agagctctcc tatctggacg ccttctgggg cgactacctg agtggcgccc tgctgcaggc   1020

cctgcggggc gtgttcctga ctgaggccct gcgagaggct gtgggccggg aggctgttcg   1080

cctgctggtc agtgtggatg aggctgacta tgaggctggc cggcgccgcc tgttgctgat   1140

ggaggaggaa ggggggcggc gcccgacaga ggcctcctga tccaggactg gcaggattga   1200

tcccacctcc aagtctccgg gccaccttct cctgggagga cgaccatctc tacccctaga   1260

ggactgtcac tctagcatct ttgaggactg cgacaggacc gggacagcag gccccttgac   1320

agcccctccc acaggatgtg ggctctgagg cctaaaccat ttccagctga gtttccttcc   1380

cagactcctc ctacccccag gtgtgccccc ttagcctccg gaggcggggg ctgggcctgt   1440

atctcagaag ggaggggcac agctacacac tcaccaaagg cccccctgca cattgtatct   1500

ctgatcttgg gctgtctgca ctgtcacagg tgcacacact cgctcatgct cacactgccc   1560

ctgctgagat cttccctggg cctctgccct ggcctgcttc ccagcacaca cttctttggc   1620

ctaagggctt ctctctcagg acctctaatt tgaccacaac caacctgggc ttcagccaca   1680

tcagtgggca ctggagctgg ggtgcacatg gggcctgctc accttgccca cacatctcca   1740

gccagccagg gccctgccca gcttcaattt acagacctga ctctcctcac cttcccccct   1800

gctgtccaga gctgaacata gacttgcact tggatgtcac ctggagtgtc acatgggagt   1860

gttatggcag catcatacca aggcctactg ttgcacatgg ggccaaaacc agtaaacagc   1920

caccttcttg gaaagggaat gcaaaggctt tgggggtgat ggaaaagacc ttttacaaat   1980

gataccaatt aaactgccct ggaaagggca taggtgggca tcggc                   2025


<210>  780
<211>  4390
<212>  DNA
<213>  Human

<400>  780
acgagatggc tgtgtgcgca ggcgcaagac tagcgctctt gggaccggaa gttaaggcgt     60

tcgcggcgtg tgaatccagg gcctgaaaac ccagaatgaa cttgtgtcca tcccagagat    120

cactgcagat gtcatgaggt accctttgtg tcaccagctc aagcaggcct ctggccactt    180

tatcatctgt ggtggtcctg tgccgtgacc aggaggaaaa attagctctt tgaagagaaa    240

gtagttctct attgcaggca ctggcctctt aaattgttgc aggtggggaa tggatgagaa    300

tatttgtttt gggtgatcag aactgagact cctattgtgg attagtaaca tgcctcctcc    360

tagaacaagg gagggcaggg atcgccgaga ccaccaccgg gctcccagcg aggaagaggc    420

cttggagaaa tgggactgga attgtccaga gacgcgtcgc ctcttggaag atgccttctt    480

ccgtgaagag gattacatcc gtcagggttc tgaggaatgt cagaagtttt ggaccttctt    540

tgaacgcctg cagagattcc agaatctcaa gacctccagg aaggaggaga aagaccctgg    600

acagcccaag cacagcatcc cagcgctggc cgacctacct cgcacttacg acccacgtta    660

ccgcatcaac ctctctgttc ttggccctgc cacgcggggc tctcagggac tgggcaggca    720

cttgcccgcg gagagagtgg ctgagttccg ccgagccctg ttgcactacc tggactttgg    780

ccagaagcag gcatttgggc gtctggccaa gctgcagcgt gagcgggcag ccctccccat    840

cgcccagtat gggaaccgca tcctgcagac gctgaaggag caccaggtgg tggtagtggc    900

cggtgacacc ggctgtggca agtccactca ggtgccccag tacctgctgg ctgctggctt    960

cagtcatgtg gcgtgcaccc agccccggcg gatcgcctgc atctcactgg ccaagcgtgt   1020

gggctttgag agcctcagtc agtatggctc acaggtcggc taccagatcc gctttgagag   1080

cacacgttcg gcggccacca agattgtatt cctgacagtg gggctgctcc tgcgacaaat   1140

ccagcgggaa cccagcctgc cccagtatga ggtcctgatt gtggatgaag tccatgagcg   1200

gcatctccac aacgatttcc tcctgggcgt cctccagcgc ctgttgccca cgcggcctga   1260

cctcaaggtc atcctcatgt cggccaccat caacatctcg ctcttctcca gctatttcag   1320

caatgcccct gtggtacagg tgcctgggag gctgttcccc atcacggttg tgtaccagcc   1380

gcaggaggcg gagccgacca cgtccaagtc agagaagctg gacccgcggc ctttcctgag   1440

ggtgctggag tccattgacc acaagtaccc gcctgaggag cggggtgacc tcctcgtctt   1500

cctcagcggc atggcggaga tcagcgccgt gctggaggct gcccagacct atgccagcca   1560

cacccagcgc tgggtggtac tgccactgca cagcgccctg tctgtggccg accaggacaa   1620

ggtatttgat gtggcacccc ctggagtccg gaaatgcatc ctctccacca acattgctga   1680

gacctcagtc accattgacg ggatccgctt cgtagtagat tccggaaagg tgaaggagat   1740

gagctacgat ccgcaggcca agctgcaacg gctgcaggag ttctggatta gtcaggccag   1800

cgcagagcag cggaagggcc gggcgggccg cacgggcccc ggagtctgct tccgcctcta   1860

tgccgaatcg gactatgatg ccttcgcccc ctaccccgtc ccagaaattc ggagggtggc   1920

cctggactcg ttggtgctgc agatgaagag catgagtgtg ggggaccccc gaaccttccc   1980

cttcatcgag cccccaccac cagccagcct ggaaaccgcc atcctctacc tccgggacca   2040

gggggccctg gacagctcag aggccctcac acccattggg tccctgctag cccagctgcc   2100

tgtggacgtt gtgattggga agatgctgat cctgggctcc atgttcagcc tggtggagcc   2160

tgtgctcacc atcgcagccg cacttagcgt ccagtcgccc ttcacccgca gcgcccagag   2220

cagcccagag tgcgcggcag cacggcggcc gctggagagc gaccagggtg accccttcac   2280

gctcttcaac gtcttcaacg cctgggtgca ggtgaaatct gaacggagca gaaactctcg   2340

caagtggtgc cgccgccggg gcatagagga gcatcgactg tacgaaatgg ccaaccttcg   2400

gcgccagttc aaggagctgt tggaggacca cgggctgctg gctggggccc aggccgcgca   2460

ggtaggggac agctacagtc ggttgcagca gcgccgggag cgccgggccc tgcaccagct   2520

gaaacgccag cacgaggagg gcgcggggcg caggcgcaag gtgctgcggc tgcaggagga   2580

gcaggacggc ggctccagtg acgaggacag ggctggccca gcccccccag gggccagtga   2640

tggcgtggac atccaggatg tgaagttcaa gcttcggcat gacctggcgc agctgcaggc   2700

cgctgccagc tcagcccagg acctgagccg cgagcagctg gctctgctga agctggtgct   2760

gggccggggc ctgtacccac agctggccgt ccccgacgcc ttcaacagca gccgaaagga   2820

ctcagaccag attttccaca cgcaggccaa gcagggcgcc gtgctgcacc ccacctgcgt   2880

cttcgctggc agccccgagg tgctgcacgc acaggagctg gaggccagca actgcgacgg   2940

aagccgagac gacaaggaca agatgagcag caaacaccag ctcctcagct tcgtgtccct   3000

gctggagacc aacaagccgt acctggtgaa ctgcgtccgc atccctgccc tccagtccct   3060

cctgcttttt agccggtctt tggacaccaa tggtgactgc tcccgcctgg tggccgatgg   3120

ctggctggag ctgcagctag cagacagtga aagtgccatc cgactcctgg cggcttccct   3180

gcggctccgt gcccgctggg aaagtgccct ggaccggcag ctggcgcacc aggcccagca   3240

gcagctggag gaggaggagg aggatacgcc agtcagcccc aaggaggtgg ccaccctgag   3300

caaggaactc ctgcaattca cggcatccaa gattccttac agcctccggc ggctcacagg   3360

gctagaagtc cagaacatgt atgtgggacc ccagaccatc ccagccaccc cccatcttcc   3420

tggcctcttt ggcagctcca ccctgtcccc ccaccccaca aaggggggct acgcagtcac   3480

tgacttcctc acctacaact gcctcacgaa tgacacagac ctgtacagcg actgtctccg   3540

aaccttctgg acctgccccc actgtggcct gcatgcgccc ctcacgcccc tggagcgcat   3600

cgcccatgag aacacctgcc cccaggcccc acaggatggg cccccagggg ctgaggaagc   3660

tgccctcgaa accctccaga agacatctgt cctgcagagg ccctaccact gcgaggcctg   3720

cgggaaggac ttcctcttta cacccacaga ggtgctgcgc caccggaagc agcacgtgtg   3780

agctgggcca ggagccctgc ccacctccgt gcagctgacc tgccctccag cccaggacta   3840

ggggcaggac tcttgcctga acccccagcc tgggcttagc cctgtggtcc tgtcccagtg   3900

cagagggcct ggagcacgga ttgtgaataa agcctcacat gctgatacac actgttaggc   3960

ctgcacctgc ccatccagaa agcagcagct gccttgttag tcctccccag ggtctagctt   4020

tccttcttcc tgctgcaggg tgctgcctga ggggtcctgg gtaggagggg cgttagagcc   4080

agcagggacc tcccatgtct ccagattcca ggtgcaggtt cttagcacct ccgcagccgc   4140

tctctcttga gtccatcctc agtctctcct accccttgaa gtagggggac cctgaatttg   4200

cccatccacc tgggtcactt tgagagttgt gcaggggggc tgggagcact ggtgttcacg   4260

tgggaccaca ggctgcacca taagacccac tcacaataaa aaaataaaag gccgagccgg   4320

gcatggttgc tcactcccgt aataaaaaaa taaaagaaca ggctgagccg ggaaaaaaaa   4380

aaaaaaaaaa                                                          4390


<210>  781
<211>  1363
<212>  DNA
<213>  Human

<400>  781
gggacgttca ggcggaagtg gcgtcagggg cgctttaggg actggacttg cagtgtaaac     60

agagacgctg caaattgctt gtggacggtg taggccgctg caggccacca tgaaccggct    120

tccggatgac tacgacccct acgcggttga agagcctagc gacgaggagc cggctttgag    180

cagctctgag gatgaagtgg atgtgctttt acatggaact cctgaccaaa aacgaaaact    240

catcagagaa tgtcttaccg gagaaagtga atcatctagt gaagatgaat ttgaaaagga    300

gatggaagct gaattaaatt ctaccatgaa aacaatggag gacaagttat cctctctggg    360

aactggatct tcctcaggaa atggaaaagt tgcaacagct ccgacaaggt actacgatga    420

tatatatttt gattctgatt ccgaggatga agacagagca gtacaggtga ccaagaaaaa    480

aaagaagaaa caacacaaga ttccaacaaa tgacgaatta ctgtatgatc ctgaaaaaga    540

taacagagat caggcctggg ttgatgcaca gagaaggggt taccatggtt tgggaccaca    600

gagatcacgt caacaacagc ctgttccaaa tagtgatgct gtcttgaatt gtcctgcctg    660

catgaccaca ctttgccttg attgccaaag gcatgaatca tacaaaactc aatatagagc    720

aatgtttgta atgaattgtt ctattaacaa agaggaggtt ctaagatata aagcctcaga    780

gaacaggaag aaaaggcggg tccataagaa gatgaggtct aaccgggaag atgctgccga    840

gaaggcagag acagatgtgg aagaaatcta tcacccagtc atgtgcactg aatgttccac    900

tgaagtggca gtctacgaca aggatgaagt ctttcatttt ttcaatgttt tagcaagcca    960

ttcctaaaca gcccaactgg catttaatta cccaatactg tatataaggc aaatatggac   1020

agttactttc ctcttgcctg ttcatatcct tcagtgacat tgaggaagca gtgtttctct   1080

ttttaaagga gaatagttgt caaccttcat tcatctctta catctctcac cctctccttt   1140

tttttttctt tgattttccc ccttattgat gggactgata ttcattctgt ttttgatgaa   1200

catttggaaa ctgtcgggct ttttattaaa gctctgtaga attaaaatgt tctggaatta   1260

taagcaatct ttgtttctga gtgttatttt tattttggat atagctttga tgtaattaaa   1320

ctggaaactc tttcctgaat tgtctgtaaa aaaaaaaaaa aaa                     1363


<210>  782
<211>  2639
<212>  DNA
<213>  Human

<400>  782
ctgcttcctg cacgggtggt ccccaagcac tgcgggaccc cagcccaaag cggaccttga     60

ctaccgccca gccccgcgct cccaggacct cccgcccgcg gagcccactc ggattgctct    120

ccgcccgggt cggcggaggc cccgtctcct gtacccggcg ctgggactgc tccgcaccgc    180

gcggctccct ttcagcagct gcgggagcat gcggaggagg ccctgccggc cccgcgggtc    240

atggaggagt tccggcgctc ctacagccgc ctgtgcaggg agagtggggc cgagccccag    300

gaggctgtcc tgcagcagct gcaccagctt cccaggggcc ggctggacct ggccacgcaa    360

agcctgacgg tggagacctg cagggccctg ggcaagctgc tgccgaggga gacgctgtgc    420

acggagctgg tcctgagtga ctgcatgctc agcgaggaag gggccacact gctgctccga    480

ggcctgtgtg ccaacaccgt gctgcgcttt ctggacttaa agggcaacaa ccttcgggct    540

gcaggggccg aggctctggg aaaactcctc caacagaaca agtccattca gagcctcacg    600

ctggagtgga acagcctggg cacgtgggac gatgccttcg ccaccttctg cgggggcctg    660

gcggccaacg gcgccctgca gcggctggac ctccgcaaca accagatcag tcacaagggc    720

gcggaggagc tggccctagc cctgaagggc aacaccaccc tccagcagct ggacctgcgc    780

tggaataacg ttggcctcct ggggggccgg gccctcatga actgtctccc cagcaacaga    840

accctgtgga gactggacct ggctgggaac aacatccctg gagacgtcct cagagccgtg    900

gagcaagcca tgggccacag ccaggaccgg ctcaccacct tccaggagaa ccaagcccgc    960

actcacgtcc tcagcaagga ggtccagcac ctccgggagg agaagtccaa gcagttcctc   1020

gacttgatgg agactattga taagcagcga gaagagatgg ccaagagcag cagggcgtcg   1080

gcagcccgtg tagggcagct tcaggaagcc ctgaatgaga ggcactccat catcaacgct   1140

ctcaaggcca agctgcagat gacagaggcc gccctggctc tgtcggagca gaaggcccag   1200

gacctggggg agctcctggc cacagcggag caggagcagc tgagcctgtc acagaggcag   1260

gccaaggagc tcaagctgga gcagcaggaa gctgcagagc gggagtctaa actcctcaga   1320

gacttgtctg ctgccaatga aaagaacctg cttctgcaaa accaggtaga cgagttggag   1380

cggaagttca ggtgtcagca ggagcagctg ttccagacca ggcaggagat gaccagcatg   1440

tcagctgagc tgaagatgcg ggccatccag gccgaggagc gcctggacat ggagaagaga   1500

agatgcagac agagcctgga ggactccgaa agcctgcgca tcaaggaggt ggagcatatg   1560

acccgtcacc tggaggagag tgagaaggcc atgcaggagc gggtgcagag gctggaggcg   1620

gcgcggctgt ccctggagga ggagctgagc cgagtgaaag cagcggcact cagcgagcgt   1680

ggccaggctg aggaggagct gatcaaggcc aagagccagg cccgcctgga ggagcaacag   1740

cgcctggctc acctggagga caagctgaga ctgctggcgc aggcacggga cgaggcgcag   1800

ggcgcttgcc tacagcagaa gcaggtggtg gccgaggccc agacccgggt cagccagctg   1860

ggcctgcaag ttgagggcct gcggcggcgc ctggaagagc tgcagcagga gctgagcctc   1920

aaggaccagg aaagggtggc cgaggtgagc agggtgcgcg tggagctgca ggagcagaac   1980

ggccggctgc aggcggagct ggcggctcag gaggcgctga gggagaaggc ggcggccctg   2040

gagcgccagc tgaaagtgat ggcgagcgac caccgagagg cgctgctgga cagggagagc   2100

gagaacgcgt ctctccggga gaagctgcgg ctccgggagg cggagatcgc ccgcatccgg   2160

gacgaggagg cccagagggc gagcttcctg cagaacgccg tcctggctta cgtgcaggcg   2220

tcccccgtga ggaccctgag ccccccaaag tgagacaggc cgggaggacc cgggcgcagt   2280

aggagtgcat caggcggcgc ccgagatgga ccaggggctg cgtcccgccc gcgccgcctc   2340

tttgagaccc gggtcgtctg ttccacgcgg cggttgcggc gactgttggt ggtgtcgcgg   2400

ctgcggggga accccgtggg aggcgcctgg gaagggctcc ctaccggccc cttcttcccg   2460

gtcgacgcca cgtgggagca caccgggaag gggtcccgcg ggcgcgtctc cccctcgcct   2520

tttgcgatgt caccgtgaac gctgcggccg cctgcgcgcg gcggggtttg gaaatacagc   2580

gcgtttgcac tttgtgataa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa    2639


<210>  783
<211>  1204
<212>  DNA
<213>  Human

<400>  783
gacaccactg gccgcgaagc gcaggggggg cgcgcgcgct gccgcccgtt cccagcactt     60

gtgcagactc ctccggggaa gagcggcctc cgcggtcatc tccaacggaa ttctgccttt    120

gaagtgtcgg ggcacggcgc gtcgagggtc ctggcggcca ggcggggcgt gtgcaagggt    180

cgcgtccccc ccccgggccc ccggcccgtg gctcttggta gagcccagtg cttcatttcc    240

cgtgcgcggc ccgggcggcc ctccctttca tcagtcttcc cgcgtccgcc gattcctcct    300

ccttggtcgc cgcgtccttg gctggcgtca gaaaaatggc tacaaacttc ctagcacatg    360

agaagatctg gttcgacaag ttcaaatatg acgacgcaga aaggagattc tacgagcaga    420

tgaacgggcc tgtggcaggt gcctcccgcc agagctcagg ccccggggcc tccagcggca    480

ccagcggaga ccacggtgag ctcgtcgtcc ggattgccag tctggaagtg gagaaccaga    540

gtctgcgtgg cgtggtacag gagctgcagc aggccatctc caagctggag gcccggctga    600

acgtgctgga gaagagctcg cctggccacc gggccacggc cccacagacc cagcacgtat    660

ctcccatgcg ccaagtggag cccccagcca agaagccagc cacaccagca gaggatgacg    720

aggatgatga cattgacctg tttggcagtg acaatgagga ggaggacaag gaggcggcac    780

agctgcggga ggagcggcta cggcagtacg cggagaagaa ggccaagaag cctgcactgg    840

tggccaagtc ctccatcctg ctggatgtca agccttggga tgatgagacg gacatggccc    900

agctggaggc ctgtgtgcgc tctatccagc tggacgggct ggtctggggg gcttccaagc    960

tggtgcccgt gggctacggt atccggaagc tacagattca gtgtgtggtg gaggacgaca   1020

aggtggggac agacttgctg gaggaggaga tcaccaagtt tgaggagcac gtgcagagtg   1080

tcgatatcgc agctttcaac aagatctgaa gcctgagtgt gtgtacgtgc gcgcgtgcgt   1140

gaggccctgc cacgattaaa gactgagacc ggccctctgg ctccgtcctg gtcatttcct   1200

gctc                                                                1204


<210>  784
<211>  2558
<212>  DNA
<213>  Human

<400>  784
ggcgcacagt cagccacggt cccatcctgc tccgcgccgg tcaacgagag caaacccagt     60

gactcacctc cgccgtgcta actcctcgct agctctccct ctcacacacg ctcacacccg    120

gctcgagatg gcggcggcgg cggcggcggc gggggactcg gactcctggg acgccgacgc    180

tttctccgtg gaagacccag tgcggaaggt ggggggcggc ggcactgccg gcggggaccg    240

ctgggaaggc gaggacgagg acgaggacgt caaggataac tgggatgacg atgatgatga    300

aaaaaaagag gaagcagaag taaaaccaga ggtaaaaatt tcagaaaaga aaaaaatagc    360

agagaagata aaagagaaag aacggcaaca gaagaaaagg caagaagaaa ttaaaaagag    420

gttagaagaa cccgaagaac ctaaagtgct aacaccagaa gaacaattag cagataaact    480

gcggctaaag aaattacagg aagagtcaga cctcgaatta gcaaaggaaa cttttggtgt    540

taataatgca gtttatggaa tagatgctat gaacccatct tcaagagatg actttacaga    600

gtttggaaag ttactaaaag ataaaattac acaatatgaa aagtcactat attatgccag    660

ttttttggaa gtcttagttc gagatgtgtg tatttcattg gaaattgatg acttgaaaaa    720

aattaccaat tcactgactg tgctttgcag tgaaaaacag aagcaagaaa agcaaagcaa    780

agccaaaaag aagaagaaag gtgtggttcc tggaggggga ttaaaagcca ccatgaaaga    840

tgatctggca gattatggtg gttatgatgg aggatatgta caagactatg aagacttcat    900

gtgacatttt atcttttctt ggtgtcatct ttatgttgcc cacaatccct tgaacatgta    960

gcacaacttc ctttcctttc agttctgcca aatgctacaa tcagaagtgc agtatctttt   1020

gtgctggtta tttaacccct tgacacttag gtgctaatgt gcaaatgagg gaacttggat   1080

cttgctgcca aggggttaaa attgggaacc taagttgcta ctaaatcata gttcaaaacc   1140

taataatgtt gtcgttgttg ctatctgatt tcatagcagc agtcactaaa ttggaaacaa   1200

aaggttgcaa cgtgacaaaa aaaattgtgt agtatttacc agcaccattc agtaatacag   1260

ccttaaccat acctccttga actacttcat aacttgtcaa gaaaagcagt ttgcagcaag   1320

ggcatgtggt gtgcacctag tattaaaatt gctttgtctt aaaattgaac atgaggatat   1380

taaaaataca ttgtgaagaa gactgcttat ctcagagtga agatactgcg gctgaaaagc   1440

actagtttga tataaaatta aaatgaccaa aaccctccaa ctttgaagct aaagaaggta   1500

aacctttcca ttattgcatt acatgttgtg gaatctctcg agtgcaaaga ctgtctagtt   1560

atttatcagg ctatttctac tgatgaactg cttcaggtgg gggagggaaa cttattttta   1620

tttgcctgat ttaagtgtct gagaaacaaa tctttgttct cttaggctgc aatggaacaa   1680

ctttaccagg gttttggcat ttcctttcct ttcctttata aaacatgctc agcaaactgc   1740

accagttaac tacagtttgg taaattgtta tgttaacaat tatgacatct gcaatgtttt   1800

ataaagcaac taatttaata aaatcactgt tgtgaggact taaattttgt gttacctccc   1860

aagagatact ttttgagagt atagaacaca gctcttggga gtacagttct ctacgttctc   1920

tactaaatct taataaatgc ttgacatagt tacagcttta aaacatgagt gatttgccag   1980

gtccttatgt tgtcaccata gagcaacaaa ggtatagggc tgccttcctc ttatttattt   2040

ggggacatta ttttgttatt tagataccaa ggcctaatta attaagtacc tataagaact   2100

atttatttgg agtaactgag cctgtaactc aggtttatgg ctgttaagta tagattgggg   2160

aatctttatt atgtcttctc ctaagcagtt taaccaaatg tgtggttagt gtttttttat   2220

tcccctaaga cagaaagaac aaaaaatgtt ttaaatttct cttatatagg aaataatagg   2280

aacgtcaaag ctctgtatac ctactaagtg gaaaacaaga ccatcatcta agtgatttga   2340

gaaattaaca aaagtagtga ctacacagca ataattacag taaattaaat aaagattcct   2400

ttaaggcaga caagggctaa gatttcctta gcagtaataa tgacatacac tgaattgaaa   2460

atctatttta ttacagaaag atcagtttct aacaaatgaa aatgtatcac ctgttcctta   2520

actgtgtaaa taataattaa atttctttga aactggaa                           2558


<210>  785
<211>  13109
<212>  DNA
<213>  Human

<400>  785
gggttcctcg cggcgatccc gactctcctc ccgcggctgc agcagctgcc ggttgcacac     60

ggcctcggcg gcggcgcggc gagcgcgggc ctgtggagcg gcggccgggc gcgcggcccc    120

ggcgggcacc cctcagaggg cggccgagga agctccggga ggaggagcag gaccacgagg    180

aggtgggagg cggcggccgc ctggggacca gctccgcgcc tcggcctctc cgccccctcc    240

ccagcctttc tctcgccctc ttctcccaca ctcccggccg gcgcctcggc tttgtgcgag    300

gagatggtgt agccccctgg ccgccgaagg aggagccgga cacttgtctc ccgtctccga    360

gctgctcccc acccctggag gagagacccc cccctcggct cggcgccttc tgcgtctccc    420

ggctggtggg gaagcctctg cgccgccggc accatgagtg aacagagtat ctgtcaggca    480

agagctgctg tgatggttta tgatgatgcc aataagaagt gggtgccagc tggtggctca    540

actggattca gcagagttca tatctatcac catacaggca acaacacatt cagagtggtg    600

ggcaggaaga ttcaggacca tcaggtcgtg ataaactgtg ccattcctaa agggttgaag    660

tacaatcaag ctacacagac cttccaccag tggcgagatg ctagacaggt gtatggtctc    720

aactttggca gcaaagagga tgccaatgtc ttcgcaagtg ccatgatgca tgccttagaa    780

gtgttaaatt cacaggaaac agggccaaca ttgcctagac aaaactcaca actacctgct    840

caagttcaaa atggcccatc ccaagaagaa ttggaaattc aaagaagaca actacaagaa    900

cagcaacggc aaaaggagct ggagcgggaa aggctggagc gagaaagaat ggaaagagaa    960

aggttggaga gagagaggtt agaaagggaa aggctggaga gggagcgact ggaacaagaa   1020

cagctggaga gagagagaca agaacgggaa cggcaggaac gcctggagcg gcaggaacgc   1080

ctggagcggc aggaacgcct ggagcggcag gaacgcctgg atcgggagag gcaagaaaga   1140

caagaacgag agaggctgga gagactggaa cgggagaggc aagaaaggga gcgacaagag   1200

cagttagaaa gggaacagct ggaatgggag agagagcgca gaatatcaag tgctgctgcc   1260

cctgcctctg ttgagactcc tctaaactct gtgctgggag actcttctgc ttctgagcca   1320

ggcttgcagg cagcctctca gccggccgag actccatccc aacagggcat tgtcttggga   1380

ccacttgcac ctccacctcc tccaccactc ccaccagggc ctgcacaggc ttcagtagcc   1440

ctccctcctc ccccagggcc ccctccacct cctccactcc catccaccgg gcctccaccg   1500

ccccctcctc cccctcctct ccctaatcaa gtaccccctc ctcctccacc acctcctgcc   1560

ccacccctcc ctgcatctgg attctttttg gcatccatgt cagaagacaa tcgcccttta   1620

actggacttg cagctgcaat tgccggagca aaacttagga aagtgtcacg gatggaggat   1680

acctctttcc caagtggagg gaatgctatt ggtgtgaact ccgcctcatc taaaacagat   1740

acaggccgtg gaaatggacc ccttccttta gggggtagtg gtttaatgga agaaatgagt   1800

gccctgctgg ccaggaggag aagaattgct gaaaagggat caacaataga aacagaacaa   1860

aaagaggaca aaggtgaaga ttcagagcct gtaacttcta aggcctcttc aacaagtaca   1920

cctgaaccaa caagaaaacc ttgggaaaga acaaatacaa tgaatggcag caagtcacct   1980

gttatctcca gaccaaaatc cacaccctta tcacagccca gtgccaatgg agtccagacg   2040

gaaggacttg actatgacag gctgaagcag gacattttag atgaaatgag aaaagaatta   2100

acaaagctaa aagaagagct cattgatgca atcaggcagg aactgagcaa gtcaaatact   2160

gcatagagga acagactaag gagagatagg actttaatct ggaggaaaaa tatcctacaa   2220

acaacaactg ttcacaacag caaaccccta catttatgag ctgtaagaag aaaatggaga   2280

caaacagaag gagggaaaaa ccaacctact ctgaaagcct tcagacatta tgactctggt   2340

gataagctct ttccctctcc gtttgctgct tttttctggc ctttacaaca gaatggaaga   2400

gaatcattta agagttcctg taacagttat gcagaaaata ctaaaaccca tcaggcaaga   2460

tcaccacgca ttgaaatatt ttcatatcaa gataaagtcg cacattttcc acaatacatt   2520

gctaaaataa agaggagaaa ggcttaggaa gtttttttgc agagagtgct ggtaaagaat   2580

tgagcaagtt tgctattgta ttgtaatgtt tctctcaggt ttgttcttcc tatcatgttt   2640

gatattccat gaataattga gatcagccct atgtaagtta agatcataat atgtggaaca   2700

aatggaattg taagtgcttt caaagggtaa tatttataag aaagtgtccg aaaaatgttt   2760

cttcagcttg agaaatttta gaatgatagg aagtttctcg agttagcctt catgcaattt   2820

tgtagattaa aacataaaat ttgtccagaa cttaaagatt tagatgcctt cctaaattgt   2880

tacaatgctt taccaaatct atgacttcta cataacacaa accagtggtc aaatgtaaac   2940

actatattgt agatttactg taggttttca acctttttta gatttatgca tgtggacatt   3000

tttataatgt aattacaatc accacaaggt tagctttttt aattgcagac agtaatgcat   3060

gtcacactaa tatgtagtgg ccttttcaag gcctagtccc agggaaaaca ttttgtagag   3120

tataggggag tgggaggaag gggaggaata attttttatt taaagttgat ttctgcacta   3180

tctttttctc agttacctgc atgaataaat aatgagaaat attttgtgac tttaattggt   3240

aaatatgtta caaaaccaag tacttaatct tttacatcat gtcttcagct atttgtattt   3300

taaccagtaa tttcaatggt ctgaaacatg attctgagct tcacataata tcttaactgt   3360

ggaactcaaa agtttgatca ctgaatttgg cagttattat tacctaggta cccccgctgt   3420

tacacaggtg tttagatacg tgttcctgaa tgaagctgct tttgaatttt gttatgttga   3480

aatgcaagaa ataacaatga tggcagcaat taaggtcaca gaaatcatta ggtaaaggaa   3540

aaccaatgag gagttctgca gttttctttt aataagtaaa gtgagacttg ggtggtggga   3600

agaaggaagg tgggaagaag gaattagaca ctctgcctgc cactctgcgt gtgtgtgctc   3660

tcgcgcacgt gctgtctata tggaagccac tcccttttct ttcctttgaa actggtaagg   3720

ttaaaatagg ggagaaatcc tacatgttgg aatgatagct ttttggaaaa tttaagaaac   3780

tctccaggct ctccatcttg atttatgctt gagttgttat gtgccatatt tgctttgaac   3840

tctgattatc agaagtttta ctaaaacttt gaaataattc actttcatct gctttctaga   3900

ttttgtacat ctcagtccat aaagcaaagc ttgttgatag tgtagttttc taaacgctgc   3960

aaatttgcag cctttaccac tacaaagaag tttggatgag ggattttttt tttctttgtc   4020

aaaatagttc ctgtttctgt agaaatttca tttttagatt aaactgtgat ggatgagcta   4080

tcataattca agtatacatt tcttttttct atcagatatt cattgtcatg cagtagtagt   4140

aaaaacatca aagatgcagc aagcttatta agtattattt tctaaaagaa ataggaggca   4200

ttttcatctt tattattgta cttttggtta tgcaaacact ttgataatat aaacagttat   4260

gtcccctata aatctggtca gcaacctctt ttgattttgt tgggtaagtt aaatagtctg   4320

tagtaggtag agtactgggt acaagtggtc caaactaaga taagagacta aaataaaatg   4380

ctaaatctta aaagaaactg ggtttatgca ctaaacgttt tgtgccttgg tctaatatta   4440

acatgatgta tgtgtaaact gacaaaaaaa aaaaaaaaaa aaaaccagtg ttgaatcatg   4500

ctatatttcc catcatccca gattgctaaa tgttctttcc aagaagtctg aatgaattat   4560

tatatacatt tgctatcata catgacagtt gtgtcattat tagagatttc agtaattaaa   4620

atgggaaaca gaagcctaag ttatttacct tatcaaaacc acgttccttg gaaccacatt   4680

attatgatgg tttttgtgct cttgtacgtt ggatgtctta agctgagtac agtttagggg   4740

atcctttcta atgacaggaa ggcactgctt tcctcaacac tgtgatctga cctgtgacaa   4800

gtctgtacta tccactatgt aaatggctca caagtcaatt gcaaacaaac tgaatgtaca   4860

aatcttagtg ctggtgctga aatctcttca gaatagtcat catgatttaa aagtttgttt   4920

aaaaatttgc aagcatcaag tgtcaatcaa aactgaagat gaaacactaa tgaatgttga   4980

attctcatgc ttttaggtgt acttcctttt tagaattttc agttttctgc tatttttacc   5040

gtaactattt cgtttaaatt tgtttcattt aagtttccta cacgctaact tcgtttgtgc   5100

gattgaaata aaattgcagt atatatatgt tgcttgtttg tgacacttag ataatcttct   5160

gaaataattt gttttaaagt aagttatatt ggatgtgaaa aacacctttt aaagtccaag   5220

actttactac ttaaaagttt acatgtcacg tcactattct ttacagattt catagaagtc   5280

gtgaatacta agtaatgtat acaaaagaaa tatgtgatga tgtgtctact ttttgtttga   5340

aataactgtt gggtgttccc tcttcttatt ttctctctgc ccaccttgac acagtaactt   5400

cctcttatag tcaagatgat gattaagtgt ttaattttta ttccattttg ttctgcaaca   5460

cgttcaggta cttaaaactc attcatgcag ttagaattat cctttatgta gtttgcatgg   5520

taaaggacat tgtgtggtaa agggcattat tgagtaatga attttaagta tagcaaaata   5580

tgtatagtgt ttatacatga tgctgatttc ttaaaaccta catataagca gtagtacttt   5640

ttctctatta taaagtatta attttgagtt ccattttata attctgatgt cttcattaga   5700

aatacaaaaa tacaatcctt gtattttttc tttgaccaga cccaaatttt ccccttcccc   5760

cctccattct cctctccact tctcgtggac cgcgtgttcc caatattcat taacatttgc   5820

agccattaca gagttacagt tgtaaaattt tcagctgttt tttttttttt ttttttgctc   5880

tagcctgtct catgttcttg cttctcttca tatgtaagtc agtatttttg tctacaaatt   5940

aaaagtcact tgtcattcaa aaatgagtta agtaacatga taatctttta aatttaccta   6000

gctacaactt ttatgtctct tgtaaattta tatatacttt cagtgccatt gtgaagaatt   6060

ggccttttaa ttctaagtag tattacccta tgaagcacag tgtgcaaagg tatgctacaa   6120

ggtctcttta attcctgtgt ggccattata attttataac accattaccc tttaaattct   6180

accgattata agcagcgtaa aagtaactat ataaagcaaa catcgcaaag gaactctgca   6240

ggagctctta attcctttat gtagctatca taaaattcac tttcctgaag acatttactc   6300

tcattcactt ccaaactcca aacctttttc tggtagcacc acttttgttt ttaatagaaa   6360

gatgagttca tatctgtaca tctctccaaa gctctaagga atgagaaaag gatcctagta   6420

tattgaaatt actgatgttt aatacctctg ccttttcact aaaagccatt taatattttt   6480

aaagtcaaaa cttgacatac aggtatttat aaggaatctc catgactctg aaggaatgaa   6540

attgatgtag gtagctttgg ctatgtaaag acatagtaga ggacaattac ttaaagaaga   6600

gttttctttt gaggatttgt agatttgact aagcagctga agtcagtaac ccctcaagaa   6660

agtccgttta tagaagccaa gaactgttgg aggtctgtga tgcaggtttt tctgttccca   6720

acatcaaaag ctgtggatta tttggtgtgt tcccctttat gttatctctc gataattttt   6780

gagacatcaa gattttttaa aatatcaata ctggaaagat gaaaccttca aattaaaacc   6840

taaaattgat tagaaagaaa agtaaaatat taatgcagta aatttaggat ggttacagat   6900

actcaccatc aacataaata aatggagttc taggataaat tatttgtgga atactaatgg   6960

tcaagtcaca taagagtaaa atcttttggt gaggagacac atttgacaac tgctaaagaa   7020

ttaactaaat ttgtctttct aaatagtttt ctttataaag taacagaaac attgtaaaag   7080

gataaatgac tgtcataatg acttaggatg ttgtaagaat gtctgccaca tttattggtt   7140

atttctgttg aaatctgaag gaatcgatac atctgaaaat tgagaaaggg aaataggact   7200

gtccccgtta cagatactct gtgatgcaca caaccttcta aacggaagtg ttagtatcat   7260

ttaaagcaca tagtaggcct tgagtatttg cagattaaca tgcagaaaaa atcaaagatg   7320

aagccccaat taagtgtttg aaccaaagaa tcacagtcac tgagctgcac ccccgttctg   7380

tgaagcatgt taaatactca taaagagcag agagcagggc ccgtagacgc ttctggtgta   7440

ggacacagga attctaggca gagggagaaa attaggggcc ccagttggtg gctgagagta   7500

aaaagaatat accatttgag tagtgctgtt ctttttcctc agtttttaaa gacatataat   7560

tcctagtagt taggacatct aaatagctcg gtaaactggt cagaggcggg aggattgctt   7620

gaggccagaa gttttgagat cagcctgggt aacagggaga ctcatttcta caaaaaaatt   7680

taaaaattta ggccaggcat ggtggtgcac acctgtaatc ccagctactc aggagactga   7740

agcgggagga tcacctgagc ccagggagga cgcggctgca gtgagccgtt atcatgccac   7800

tgtactccag cctgggtgac agagcgagaa cctgtctcta aaaaaaaaaa aaaaaaattc   7860

taagagaata tagcttttca tagaaattat tagaaaagct tacatatttc attagagagc   7920

ccagtttgtt agactacatt tattccgtaa aagttctata tacaaatgac aacccatagt   7980

ttatcatgta aatctgattt aactgttccc ttcaattcca agaaagattt cttcagcagt   8040

agatgacaat tctaaaagca taaagaaata actaataaag gagatggatg atgttatagg   8100

ttggtttggt tgggttttag taaatagtta ttcttctaag aaggcttaga aaatcgagaa   8160

ttgaatagtt ggtactttga attccatagg aaaaagcact cagaagaaaa agtctacatt   8220

ggctagtgtt tagattgaga gttaattttc ccatcaagtc caaaagtttc catccaagtc   8280

tatagaaact gagagaaaag gttcttggct tacacttaaa atacacattg ttgcaaccat   8340

ataagagaga tacattacag aacgctttta aaaatttggt ctcttaagcg cctaacagtc   8400

catgctttag tcacatctgt gaaacctctt ttcttttttt ctttttcttt tatttttttt   8460

tttaaagatt aaaggcattt taaaaataaa tgtttcatgg ccgggcatgg tggctcacgc   8520

ctgtaatccc agcactttgg gaggctgagg tgggcagatc acctgaggtc aggagtttga   8580

gaccagcctg gccaacatga tgaaacccca tctctactaa aaatacaaaa aaattggctg   8640

ggcatagtgg tgggcacctg taatcccagc tcttcgggag gctgagacag aagagtcgct   8700

tgaatccagg aggtggaggt tgcagtgagc taagaccgcg ccactgtact ccagcctggg   8760

cgacagagcg agattccatc tctaaataaa taaatgtttt tcaacgtgtt ttatgtgaga   8820

aataccagct tttcattatt actaccagtt gatctcaggt gtcacttggt tggttctgct   8880

gaccgaggca ctgggcattt taaatatgga gtttccctcc acccattgat caagtctgag   8940

gtttgtccat ccttggtggc aggctagctt aaccatggat tcacaaaccc catttgattg   9000

tcgtaagtca taaggccacc ccagtgccag tggttgggca tcacagtgag tctgaggtga   9060

tgaatttgag ttagctgtag gctagttccg caactcagca atagcccatg gatggttggt   9120

aaaagacgtt gactttgcca cttaaatttc caggagaaga atagcttata gtttatctga   9180

ggaaagtaat tgggaaggct tagatattga gaagaaagcc ctgttaaaat ctaggtagca   9240

tttcctttct tctttattac tagagggatg ggaggttcag gcctgagtca ggactttaca   9300

atttggtgtc cttcccagag gtactttggg cttgatcatt ttaagtttca attgcaaaaa   9360

aaaatttttg acggagtgtt gctctgtcac tcaggttgga gtgcagtggt gcgatctcgg   9420

ctcactgcaa cttccccccc ctgggttcaa agggattttc ctgcctcagc ctcccaagta   9480

gctgggacta caggcgcgtg ccaccatgcc cgactaattt ttgtattttt agtagagatg   9540

gggtttcacc atgttgccca ggctggtctt gaactcctga gctcaggtga tctgcccgcc   9600

tcggccttca attgcagaag tttttgaagg gagaatattt gatcctcaca taaaatgtcc   9660

ttgtttctga aagaaaacat ggtaaaaatt gttattgagt ccatgtcttt gccaccttgt   9720

tggacttgat ttccctttct ctgtgttcct cccgccctca gtctctctca gtctgtcctt   9780

ttttgtgtgt ggagttgtgg gcaggtcatt ggactgggac tgactttacc agttttcagg   9840

ctgtggggct agtcagtcat tctctctgag ccttctacct ctaaagttga gttctttttt   9900

taaattcttt ttgttttgtt tttatttttt ccttgccact atacaagcaa ggatagataa   9960

agctttttat tattattgtt attattatta tttcgagaca gtctcgctct gtcatccagg  10020

ctggagtgca gtggtgtgat ttcagctcac tgcaacctct gcctcccggg ttcaagcgat  10080

tctcctacct cagcctcctt agtagctggg actacaggca tgcgccacca cacccggcta  10140

atttttgtat ttttagtaga gacagggttt caccgtattg gccaggctgg tctcgaactc  10200

ctgacctcag gtgatccacc caccttggcc tcccaaagtg ttgggattac aggcataagc  10260

gaccgtgccc atccccgata aagttgagtt ctgaatttcc tctttcactg tattctcggc  10320

agctactggt tggtttattc ttttttttta atcttttttg gtttattctt cttttgatct  10380

ttgaagagaa ggagaaaaaa gatctgagtt tggctctccc atcttaagtg cagcttttag  10440

ttgttttata gtcatagacg ctattgcact ggacagcatg catcctggat gtaaacaatg  10500

cggaaaaatc aatggagtga ccatcttggg gtcagtggtg ttgcataaag caccagtggt  10560

gtgctgttct gtgtcagttt cctctgcgcc acgtgctttc acagtttgaa ttaccagcat  10620

ctctgtggtg gcttcagtac attctccatt gtgcttcaac ctggaagcac attctgccgt  10680

tcagaaagac tgattccaat catgtaatgg gaccacacga gatccatgct ccaattatat  10740

gaatagcaga aggtccattt gactcttgta gttcaagagc tgtttctaag taaacagact  10800

ttccagagct cgatgaagtg aagaagccct tctttcaatt cctgggcaga attcagtggt  10860

tttcatatca tctgaacctg ctgtgctgct gtttattcta tcactgtcag ccttgaaagg  10920

aaaaaaggaa taatcttacc ctcctgccct tcttatttta tatcttccat cttatccatc  10980

tatatccatg tagtcattcc ttccgagttc cctggtttta atccaaaaga ctctgtttaa  11040

cagcaatgtc ttggcagacc aggtgccgct tccgtgccat ttgagggctc tgagtctttg  11100

cttcgtctta ggaagataaa gataatttgg cagaaagtca gagatggaaa tagcagtttg  11160

ggatgataaa agatgggtcc tgttttgctg acattctttt actttggttc ttggtgcgtg  11220

tcctttggga ttcatttctt gctagcatga ataggacatg cttttcgtta ggtgcttttc  11280

ttttttggag aacatgaagt gtttctaaca aaactgaatg agctagaaag aattctattt  11340

tgagacatct gtagttgatg caaagtattt ctgtaatcct caatgacagt acttacatat  11400

ttgcatagaa tttttttttt aatttttgag gaaacctctc tggagtctgt atttatagga  11460

gcatcctgaa agtccctatt atgtagctgg tgggagcgag agagggacag ccacactcgt  11520

gctgtgagca gagcacaact tcaggcagag tgaatgcctt ctgagttctc attggaagct  11580

ttctgttgct cagcctctgg cagatttcag aaccttctac ttaagccagg tgtggtggtg  11640

cgtgctccta ggcacagcga ctcggggggc tgaggcagaa ggatcacttg agcccaaagt  11700

tggaggccag cctgggcaac atagcgaggc ctgtctcctt aaaaaataaa taaataaata  11760

ataaataaat aaataaataa aaaccttgtc cttgactatt gtgctgtctg ctgccccttt  11820

gtagggatgg ggttggggtc agaataagca tgtgcatgaa tggcggaaag ctttggtggt  11880

gtttgtttgt ttgtttgttt tttgagaggt gggggagtca gcagtgaacc tttctggtta  11940

aagaacaacg tacataattt ctattatgag atttagaagg ttaaatactt ttttttttca  12000

ggcctaccaa gttgatagac caaaagtata tagtagaaca gcacagtaga aaaaatttaa  12060

aagtgaattt cttatggtcc aaaaggatgg atagtcacag tccataacct ttcataatat  12120

atgctggaat tggaatctct tgtcatcttg ctttgctctg aattttagaa ctagaagtgt  12180

gcatgtatgt caaaagatta tgcagagcta ttttctttgc taacaatgta aacatttgca  12240

ccccatgaat gggactttat aatctggaag tgagcctaag gttgcgtata ctgaagtcat  12300

gttttaaaag ttaaggttga cttaaacata tacaaggctg tattttaatt gtaactagaa  12360

atcatttact atgcatacag aacctcatgt atcttatcat ggaatttgtg aattaatggg  12420

ccttgccgaa ttcaagggta agggaaactg gtaacaactt gttttaaatc aacatactat  12480

aagctcctgc ttgcttgact caagttgttt gaaaatctga attaaacagg atctcattgt  12540

caggaaacat cttctaagct tgacatctac gtttaagaag ggaacgtgga agagaaggtg  12600

agacatgaaa ctaaaacagc tgggagggta ggatcagact gcacctgatt tttggaccaa  12660

agtttcatat aggaataaat aaaaaggagg accacttgtg agccaaccta ggaaggactt  12720

gccagaaagt agcagctcct gctgcaaaat acagtgcctt caaaatgatt ctctgtgtga  12780

attgcatgca atttcatgta accataaagt gtaacctgta tgtgcatgac atgtgtctag  12840

aatgtgtaaa gttaggattc agcaggaagg ggcctggccc tgtcactgtg gtggatcagt  12900

ggacctgctg aagtcactgg actcatgtga cttaggtttg cagcatcaga cccctgtgtt  12960

tgcattaagt ggccacatcg ttgaaatcgg atcaatctct ccctcagctt tctttcctac  13020

tttgcagctt tgctggtttt aactgcttca ttcttctgct tcttggtatc cttttttctt  13080

ttgaaataaa aacatgaaat acttaattc                                    13109


<210>  786
<211>  2204
<212>  DNA
<213>  Human

<400>  786
gtggggcccc agagcgacgc tgagtgcgtg cgggactcgg agtacgtgac ggagccccga     60

gctctcatgc ccgccacgcc gccccgggcc atcccccgga gccccggctc cgcacacccc    120

agttcggctc accggtccta tctggggcca gagtttcgcc cgcaccacta cagggccgct    180

ggggagtcgg ggccccccag atctgcccgc ctcaagtccg cgggacgtca cccccctttc    240

cacgctactg cagccgtcgc agtcccaccc ctttccggga ggtgagggaa tgagtgacgg    300

ctctcccgac gaatggcgag gcggagctga gggggcgtgc cccggaggcg ggaagtgggt    360

ggggctcgcc ttagctaggc aggaagtcgg cgcgggcggc gcggacagta tctgtgggta    420

cccggagcac ggagatctcg ccggctttac gttcacctcg gtgtctgcag caccctccgc    480

ttcctctcct aggcgacgag acccagtggc tagaagttca ccatgtctat tctcaagatc    540

catgccaggg agatctttga ctctcgcggg aatcccactg ttgaggttga tctcttcacc    600

tcaaaaggtc tcttcagagc tgctgtgccc agtggtgctt caactggtat ctatgaggcc    660

ctagagctcc gggacaatga taagactcgc tatatgggga agggtgtctc aaaggctgtt    720

gagcacatca ataaaactat tgcgcctgcc ctggttagca agaaactgaa cgtcacagaa    780

caagagaaga ttgacaaact gatgatcgag atggatggaa cagaaaataa atctaagttt    840

ggtgcgaacg ccattctggg ggtgtccctt gccgtctgca aagctggtgc cgttgagaag    900

ggggtccccc tgtaccgcca catcgctgac ttggctggca actctgaagt catcctgcca    960

gtcccggcgt tcaatgtcat caatggcggt tctcatgctg gcaacaagct ggccatgcag   1020

gagttcatga tcctcccagt cggtgcagca aacttcaggg aagccatgcg cattggagca   1080

gaggtttacc acaacctgaa gaatgtcatc aaggagaaat atgggaaaga tgccaccaat   1140

gtgggggatg aaggcgggtt tgctcccaac atcctggaga ataaagaagg cctggagctg   1200

ctgaagactg ctattgggaa agctggctac actgataagg tggtcatcgg catggacgta   1260

gcggcctccg agttcttcag gtctgggaag tatgacctgg acttcaagtc tcccgatgac   1320

cccagcaggt acatctcgcc tgaccagctg gctgacctgt acaagtcctt catcaaggac   1380

tacccagtgg tgtctatcga agatcccttt gaccaggatg actggggagc ttggcagaag   1440

ttcacagcca gtgcaggaat ccaggtagtg ggggatgatc tcacagtgac caacccaaag   1500

aggatcgcca aggccgtgaa cgagaagtcc tgcaactgcc tcctgctcaa agtcaaccag   1560

attggctccg tgaccgagtc tcttcaggcg tgcaagctgg cccaggccaa tggttggggc   1620

gtcatggtgt ctcatcgttc gggggagact gaagatacct tcatcgctga cctggttgtg   1680

gggctgtgca ctgggcagat caagactggt gccccttgcc gatctgagcg cttggccaag   1740

tacaaccagc tcctcagaat tgaagaggag ctgggcagca aggctaagtt tgccggcagg   1800

aacttcagaa accccttggc caagtaagct gtgggcaggc aagcccttcg gtcacctgtt   1860

ggctacacag acccctcccc tcgtgtcagc tcaggcagct cgaggccccc gaccaacact   1920

tgcaggggtc cctgctagtt agcgccccac cgccgtggag ttcgtaccgc ttccttagaa   1980

cttctacaga agccaagctc cctggagccc tgttggcagc tctagctttg cagtcgtgta   2040

attggcccaa gtcattgttt ttctcgcctc actttccacc aagtgtctag agtcatgtga   2100

gcctcgtgtc atctccgggg tggccacagg ctagatcccc ggtggttttg tgctcaaaat   2160

aaaaagcctc agtgacccat gagaataaaa aaaaaaaaaa aaaa                    2204


<210>  787
<211>  2610
<212>  DNA
<213>  Human

<400>  787
caggggcgga ggcggcggcc agggaggaag cggaggaggc ggaggcggcc gcggcgttcg     60

cccgcccgct cgctcgctcg gtttccccgc ccccgccggg cttaacgccg ctgaaggtat    120

ccgggtgcgc gctgtcgcaa cctgccctca tcctggcccg cgactgtaag accggaccca    180

catccagacc aatcttcctg tccgggctgc tgcgacgcgg gctccgcagg ttgcaggcgg    240

gcggccgggg cgcctgaagg ttaccgagtg catgagcgcc tagcgcttcc cgcgctgccc    300

cgcccgctgg cccgccgacc cgcccgccgg ctcgcccgcc agcccctcgg cgcccggcgg    360

cggcggcggc ggtggcggcg acggtcgcag gaggtgccgt ctgcctccca ggtgcgcgct    420

tcgctcccgg agccgcggaa ctcggcggcc gccatggcgt ccaacatgga ccgggagatg    480

atcctggcgg attttcaggc atgtactggc attgaaaaca ttgacgaagc tattacattg    540

cttgaacaaa ataattggga cttagtggca gctatcaatg gtgtaatacc acaggaaaat    600

ggcattctac aaagtgaata tggaggtgag accataccag gacctgcatt taatccagca    660

agtcatccag cttcagctcc tacttcctct tcttcttcag cgtttcgacc tgtaatgcca    720

tccaggcaga ttgtagaaag gcaacctcgg atgctggact tcagggttga atacagagac    780

agaaatgttg atgtggtact tgaagacacc tgtactgttg gagagattaa acagattcta    840

gaaaatgaac ttcagatacc tgtgtccaaa atgctgttaa aaggctggaa gacgggagat    900

gtggaagaca gtacggtcct aaaatctcta cacttgccaa aaaacaacag tctttatgtc    960

cttacaccag atttgccacc accttcatca tctagtcatg ctggtgccct gcaggagtca   1020

ttaaatcaaa acttcatgct gatcatcacc caccgagaag tccagcggga gtacaacctg   1080

aacttctcag gaagcagtac tattcaagag gtaaagagaa atgtgtatga ccttacaagt   1140

atccccgttc gccaccaatt atgggagggc tggccaactt ctgctacaga cgactcaatg   1200

tgtcttgctg aatcagggct ctcttatccc tgccatcgac ttacagtggg aagaagatct   1260

tcacctgcac agacccggga acagtcggaa gaacaaatca ccgatgttca tatggttagt   1320

gatagcgatg gagatgactt tgaagatgct acagaatttg gggtggatga tggagaagta   1380

tttggcatgg cgtcatctgc cttgagaaaa tctccaatga tgccagaaaa cgcagaaaat   1440

gaaggagatg ccttattaca atttacagca gagttttctt caagatatgg tgattgccat   1500

cctgtatttt ttattggctc attagaagct gcttttcaag aggccttcta tgtgaaagcc   1560

cgagatagaa agcttcttgc tatctacctc caccatgatg aaagtgtgtt aaccaacgtg   1620

ttctgctcac aaatgctttg tgctgaatcc attgtttctt atctgagtca aaattttata   1680

acctgggctt gggatctgac aaaggactcc aacagagcaa gatttctcac tatgtgcaat   1740

agacactttg gcagtgttgt ggcacaaacc attcggactc aaaaaacgga tcagtttccg   1800

cttttcctga ttattatggg aaagcgatca tctaatgaag tgttgaatgt gatacaaggg   1860

aacacaacag tagatgagtt aatgatgaga ctcatggctg caatggagat cttcacagcc   1920

caacaacagg aagatataaa ggacgaggat gaacgtgaag ccagagaaaa tgtgaagaga   1980

gagcaagatg aggcctatcg cctttcactt gaggctgaca gagcaaagag ggaagctcac   2040

gagagagaga tggcagaaca gtttcgtttg gagcagattc gcaaagaaca agaagaggaa   2100

cgtgaggcca tccggctgtc cttagagcaa gccctgcctc ctgagccaaa ggaagaaaat   2160

gctgagcctg tgagcaaact gcggatccgg acccccagtg gcgagttctt ggagcggcgt   2220

ttcctggcca gcaacaagct ccagattgtc tttgattttg tagcttccaa aggatttcca   2280

tgggatgagt acaagttact gagcaccttt cctaggagag acgtaactca actggaccca   2340

aataaatcat tattggaggt aaagttgttc cctcaagaaa cccttttcct tgaagcaaaa   2400

gagtaaacac ggcccagcgg tggaaccagc cattccttga caagccagca gcctgcgtca   2460

ggagaagggc tcctcgccaa cccacccaca cgctcgtctc actcaattca atgtcacact   2520

tctgcctctt gcaaaattgc tggaaaaagt aataataaat atagctactt aagatttccc   2580

atcaaaaaaa aaaaaaaaaa aaaaaaaaaa                                    2610


<210>  788
<211>  3465
<212>  DNA
<213>  Human

<400>  788
ctgcctcagg aagcttggct tcccctccca tggggaagtg ctggaatcca ctcttgcctg     60

accctcccat aagaaacaag ggaaattcct ttacgtgagc cgccttgctc agaacaaagc    120

ttggcgtgtt tcttattcct catcaatctg acaaaatggg tatttatttg tgcctctcaa    180

gcgtgtggct tggacatgat gttccgcatc gtggaagtgg ccgtgcacca agtggaatat    240

ctgttactat agtaacagtt cctttttatt gataccagaa taaacaggaa tgcaaaggct    300

gtctcacttg ttggcacatt tcagcagcct ccgttcccag gggtttaaga accgccctct    360

agaggcagcc ctccttgcta gtctgggact tcccggtgga gtgaggaacc cagcaacacg    420

ctcctgactt cccttcccaa ggactcgacc tgagaaggac acagcagtct ctgaatttca    480

tgctctcctc tttgatgtga agaaaatgaa aagctgaaca gttgtggaac tgtggataga    540

gttagacaat aaggccgcca tgtactcgga gatccagagg gagcgggcag acattggggg    600

cctgatggcc cggccagaat acagagagtg gaatccggag ctcatcaagc ccaagaagct    660

gctgaacccc gtgaaggcct ctcggagtca ccaggagctc caccgggagc tgctcatgaa    720

ccacagaagg ggccttggtg tggacagcaa gccagagctg cagcgtgtcc tagagcaccg    780

ccggcggaac cagctcatca agaagaagaa ggaggagctg gaagccaagc ggctgcagtg    840

cccctttgag caggagctgc tgagacggca gcagaggctg aaccagctgg aaaaaccacc    900

agagaaggaa gaggatcacg cccccgagtt tattaaagtc agggaaaacc tgcggagaat    960

tgccacactg accagcgaag agagagagct gtagggccag ctgccgggct caggccactg   1020

cccaccctgg cctggacagc ctccttcagc ccttctgtac ctggcagccc tgggccccag   1080

gccctgggac gtctgtgatg ttcccacctg cttctgtaga aatgtgtcac cccagagggc   1140

ctggctctcc ctgggaggct ggggccccta agctcctagg ttttccttcc aagcacccag   1200

ccctcctgct ccaagaggga taacctgcac ccctccctgc aaggggttca gagcccagca   1260

caggagcttt ctctggcaga attgaggagg aagaggtggc cctctgactt gacaagcctt   1320

ctgttctgcc caggccttcc caccaggaat ctccgaggct ccccagggcc ccgcttctcc   1380

gtacacccca gctcctaggt ctcagagaac tcccccacct gtggttttac ctgcagccag   1440

cagagcttag cttcaaggac acctgccttc aaagccactg aggggaggaa gggcagggca   1500

gactgcagat ggccttgttg ctggcatccc ggccaggtgg gcggggacta acaaagacag   1560

ctgtttaggg tcttctcccc tcacccatgc tttcatcatc ccctccgcac agcctccccg   1620

tccaggcctt ctaaccacac ctacccaggg ctgccgcatt cctgcactca gaagtctgca   1680

gcggtgcctc acaaacttga ttgtgcataa aaatcactgg ggatcttgtt aatacagctt   1740

ctaactcaat agatctggga gatcctgcat ttctaacaag ctcccaggta aggcggaggc   1800

tgctggtgtg aggaccatgc tgtgagcagc agggcgagag tgcccagggc tgatatatat   1860

tggaaatatc acccctgaag ccatcgctgg cccccacctc ctgtggactg atgccccagg   1920

gattcccacc ccacttctgc aaccccaggt atccttcatt atccacccca tcccagactc   1980

ccaccccagg gattgcccgt gaagactttg gcctagcaaa ttgtgttggt tatgtgagtg   2040

ttgttttaat cagagatgta catgattgcc aatctgcatt tcttaccagt gtgaccacac   2100

tgttacgatg caattctagc caaaaaaaaa aaaaaaaaaa aaaaaatttt ttttttttac   2160

tttttcctag tcttatggaa agcaaatata caatgatttt cagtaggctt ctggaataga   2220

aacagtggtt tgaagacccc actgccacct ttatggactg gcccctttga gtctgaatcc   2280

ccggcctctg tcacctgaga cccaacccct agctgggcca actccagtga attcacccat   2340

ttttcttctt cagaaggcct ttcctgtgtg agacccacat attttaacct tttgctccta   2400

tcccattttt aaagaattag agaataaacc aggcctgttt cttttcccct gaaatccctg   2460

cctctggctt cctaaaccca tcatctaagg tgacagagca gtgctggaat agcatctcct   2520

ttcactttcc caaaactgcc acagatagct gccactggca tgctctttga ttcctggaag   2580

caaacgtggg actgtcggag gaaagggatt gttctggtct tactcataac tgggtggttt   2640

gagggtgact gaagtcgtgc ttttcctgtg tgtgctgcca gcacagggct gtaaatgcag   2700

atattgcgcc tgtgtgcgtg tgtataagtc aagctccaag aggctcctga atgtgactgg   2760

cgtgctgaga atgtgtttac gctgtttaat gtctgccagg tgagggttac actgaagatg   2820

cacaatccct aaaataaaga tcaccacttc cccaaagaag cagccctcgg gtccatgtgt   2880

tgttcagaca tgtgaagaga agcaagacag agggtctcag atggacgagg gctctccaag   2940

ggaatgcctg gggattcacc cagtggtccc cagaggtgct ccatggaggc aacaagtcat   3000

tccatgaagc cccagaggta gaagggacct caagcaccac gccctccagg gcagccgtgc   3060

agacgacctt ggttcacttt tcaggggtcg tcccaactct gtatctccag ccactccaac   3120

tgtggaggct gtaaatccag attttcactg ttccagtctc ctttgcagct taggatggct   3180

atgtgatcag gtgtggccaa tgaaattgaa gaggaagtct acctgggctt ctgggaaagc   3240

ttttccaata aaagacacag gcatggctaa cacctccctg ggcctcttct tcctaccttg   3300

attgagggtg tgatgcctgg agccacagca gccactttgc taccatgaca aaaaggccaa   3360

gagaatcaca gagtcattga ccctatcatt atttcaccaa gccaatacca gccgccatcc   3420

ttctccagaa ttcttgtaaa taaaataaat ccctctttgt ttaaa                   3465


<210>  789
<211>  1824
<212>  DNA
<213>  Human

<400>  789
gcggtgaggg ggcgggcccg tacgccgatt ccatatgggc gccggcgcgg agcgccgcgg     60

ggcagcgcgg ggtcgccatg gctgagctgc agcagctccg ggtgcaggag gcggtggagt    120

ccatggtgaa gagtctggaa agagagaaca tccggaagat gcagggtctc atgttccggt    180

gcagcgccag ctgttgtgag gacagccagg cctccatgaa gcaggtgcac cagtgcatcg    240

agcgctgcca tgtgcctctg gctcaagccc aggctttggt caccagtgag ctggagaagt    300

tccaggaccg cctggcccgg tgcaccatgc attgcaacga caaagccaaa gattcaatag    360

atgctgggag taaggagctt caggtgaagc agcagctgga cagttgtgtg accaagtgtg    420

tggatgacca catgcacctc atcccaacta tgaccaagaa gatgaaggag gctctcttat    480

caattggaaa ataaaagtat ttgccagtgg ccatcagggc tgagggcaag aatatatttt    540

ttataaggaa ttgggaattt tagtctttta agcaaagttt acgaatgaag aaatgaagga    600

tggccacaag cgtaaggcat atgtcacttg cctctggaca ctggttattt tatgtttcag    660

tccctaaaaa atgaaatgga aaaaagtggt gctaaatcga gtcagagata ttacaggaga    720

gttttagagc ttattatttc ctgtggccag tgcttgtcct ggcagtaagg ctttcccctg    780

taacaagcca gagccctcca aggtaccaga ctcttcttac tacacaggta ctaacaggct    840

ggcaggttag agttggtgga gtctgaggag agatattttc tctttgttgc caacatcctg    900

tttaccaaaa gtgtcacccc accatcttcc ataagctgtg aaacaaaatc aatgaggtca    960

ctaacttaga agggaaagaa agttttctgg gtctttgttt tcttgatttg gggtaattta   1020

tacaagggca tacaagttga ttttaagatg tggaactggg aggtagacta gtttggataa   1080

gaactttgaa atgttccttg tggatcccca tttctggtca tcaagatgtg gatgtacatt   1140

tcttaaaatt attacatgct gcatctttca gcctggagac tgtgcagaaa catgagaggt   1200

gatgacacac taattatggg aagcagaatt actggctgat ggcccctgag gctgtgtgta   1260

acaaaatgac aggacaatct tgcagtaaca ctttcccctt gaagagaagg gggttttgat   1320

tgtgatatat actagtatct aggaatgaac agtaaaagag gagcagttgg ctacttgatt   1380

acaacagagt aaatgaagta ctggatttgg gaaaacctgg ttttattaga acatatggaa   1440

tgaaagccta cacctagcat tgcctactta gccccctgaa ttaacagagc ccaattgaga   1500

caaacccctg gcaacaggaa attcaaggga gaaaaagtaa gcaacttggg ctaggatgag   1560

ctgactccct tagagcaaag gagagacagc ccccattacc aaataccatt tttgcctggg   1620

gcttgtgcag ctggcagtgt tcctgcccca gcatggcacc ttattgtttt gatagcaact   1680

tcgttgaatt ttcaccaact tattacttga aattataata tagcctgtcc gtttgctgtt   1740

tccaggctgt gatatatttt cctagtggtt tgactttaaa aataaataag gtttaatttt   1800

ctccccaaaa aaaaaaaaaa aaaa                                          1824


<210>  790
<211>  5030
<212>  DNA
<213>  Human

<400>  790
attgaggagc agaaggagta gggtgcgggg gaggaggagg agcgccttta gtgctgcagc     60

agctgctgct ctgattggcc cggtggttca gctgcttccc tggaacaaaa ggtcaaagtg    120

gactgcagtg taaatgtaga gaagcagccg ataaaatagc attgcctgaa gaagtttgga    180

ggctgagagc agcagtagac tggccaactg cagagcaagt tgtttctcca gccgtgcggt    240

gcagcctcat gcccccaacc cagcttagcc actgtaagaa gacgttcact gtacagacga    300

ccaaacttgc cgtggaagag acagttgtga gattcccttg caaatttaca tacgagaatg    360

gcttgtgaaa tcatgcctct gcaaagttca caggaagatg aaagacctct gtcacctttc    420

tatttgagtg ctcatgtacc ccaagtcagc aatgtgtctg caaccggaga actcttagaa    480

agaaccatcc gatcagctgt agaacaacat ctttttgatg ttaataactc tggaggtcaa    540

agttcagagg actcagaatc tggaacacta tcagcatctt ctgccacatc tgccagacag    600

cgccgccgcc agtccaagga gcaggatgaa gttcgacatg ggagagacaa gggacttatc    660

aacaaagaaa atactccttc tgggttcaac caccttgatg attgtatttt gaatactcag    720

gaagtcgaaa aggtacacaa aaatactttt ggttgtgctg gagaaaggag caagcctaaa    780

cgtcagaaat ccagtactaa actttctgag cttcatgaca atcaggacgg tcttgtgaat    840

atggaaagtc tcaattccac acgatctcat gagagaactg gacctgatga ttttgaatgg    900

atgtctgatg aaaggaaagg aaatgaaaaa gatggtggac acactcagca ttttgagagc    960

cccacaatga agatccagga gcatcccagc ctatctgaca ccaaacagca gagaaatcaa   1020

gatgccggtg accaggagga gagctttgtc tccgaagtgc cccagtcgga cctgactgca   1080

ttgtgtgatg aaaagaactg ggaagagcct atccctgctt tctcctcctg gcagcgggag   1140

aacagtgact ctgatgaagc ccacctctcg ccgcaggctg ggcgcctgat ccgtcagctg   1200

ctggacgaag acagcgaccc catgctctct cctcggttct acgcttatgg gcagagcagg   1260

caatacctgg atgacacaga agtgcctcct tccccaccaa actcccattc tttcatgagg   1320

cggcgaagct cctctctggg gtcctatgat gatgagcaag aggacctgac acctgcccag   1380

ctcacacgaa ggattcagag ccttaaaaag aagatccgga agtttgaaga tagattcgaa   1440

gaagagaaga agtacagacc ttcccacagt gacaaagcag ccaatccgga ggttctgaaa   1500

tggacaaatg accttgccaa attccggaga caacttaaag aatcaaaact aaagatatct   1560

gaagaggacc taactcccag gatgcggcag cgaagcaaca cactccccaa gagttttggt   1620

tcccaacttg agaaagaaga tgagaagaag caagagctgg tggataaagc aataaagccc   1680

agtgttgaag ccacattgga atctattcag aggaagctcc aggagaagcg agcggaaagc   1740

agccgccctg aggacattaa ggatatgacc aaagaccaga ttgctaatga gaaagtggct   1800

ctgcagaaag ctctgttata ttatgaaagc attcatggac ggccggtaac aaagaacgaa   1860

cggcaggtga tgaagccact atacgacagg taccggctgg tcaaacagat cctctcccga   1920

gctaacacca tacccatcat tggttccccc tccagcaagc ggagaagccc tttgctgcag   1980

ccaattatcg agggcgaaac tgcttccttc ttcaaggaga taaaggaaga agaggagggg   2040

tcagaagacg atagcaatgt gaagccagac ttcatggtca ctctgaaaac cgatttcagt   2100

gcacgatgct ttctggacca attcgaagat gacgctgatg gatttatttc cccaatggat   2160

gataaaatac catcaaaatg cagccaggac acagggcttt caaatctcca tgctgcctca   2220

atacctgaac tcctggaaca cctccaggaa atgagagaag aaaagaaaag gattcgaaag   2280

aaacttcggg attttgaaga caactttttc agacagaatg gaagaaatgt ccagaaggaa   2340

gaccgcactc ctatggctga agaatacagt gaatataagc acataaaggc gaaactgagg   2400

ctcctggagg tgctcatcag caagagagac actgattcca agtccatgtg aggggcatgg   2460

ccaagcacag ggggctggca gctgcggtga gagtttactg tccccagaga aagtgcagct   2520

ctggaaggca gccttggggc tggccctgca aagcatgcag cccttctgcc tctagaccat   2580

ttggcatcgg ctcctgtttc cattgcctgc cttagaaact ggctggaaga agacaatgtg   2640

acctgactta ggcattttgt aattggaaag tcaagactgc agtatgtgca catgcgcacg   2700

cgcatgcacg cacacacaca cacagtagtg gagctttcct aacactagca gagattaatc   2760

actacattag acaacactca tctacagaga atatacactg ttcttccctg gataactgag   2820

aaacaagaga ccattctctg tctaactgtg ataaaaacaa gctcaggact ttattctata   2880

gagcaaactt gctgtggagg gccatgctct ccttggaccc agttaactgc aaacgtgcat   2940

tggagcccta tttgctgccg ctgccattct agtgaccttt ccacagagct gcgccttcct   3000

cacgtgtgtg aaaggttttc cccttcagcc ctcaggtaga tggaagctgc atctgcccac   3060

gatggcagtg cagtcatcat cttcaggatg tttcttcagg acttcctcag ctgacaagga   3120

attttggtcc ctgcctagga ccgggtcatc tgcagaggac agagagatgg taagcagctg   3180

tatgaatgct gattttaaaa ccaggtcatg ggagaagagc ctggagattc tttcctgaac   3240

actgactgca cttaccagtc tgattttatc gtcaaacacc aagccaggct agcatgctca   3300

tggcaatctg tttggggctg ttttgttgtg gcactagcca aacataaagg ggcttaagtc   3360

agcctgcata cagaggatcg gggagagaag gggcctgtgt tctcagcctc ctgagtactt   3420

accagagttt aattttttta aaaaaaatct gcactaaaat ccccaaactg acaggtaaat   3480

gtagccctca gagctcagcc caaggcagaa tctaaatcac actattttcg agatcatgta   3540

taaaaagaaa aaaaagaagt catgctgtgt ggccaattat aatttttttc aaagactttg   3600

tcacaaaact gtctatatta gacattttgg agggaccagg aaatgtaaga caccaaatcc   3660

tccatctctt cagtgtgcct gatgtcacct catgatttgc tgttactttt ttaactcctg   3720

cgccaaggac agtgggttct gtgtccacct ttgtgctttg cgaggccgag cccaggcatc   3780

tgctcgcctg ccacggctga ccagagaagg tgcttcagga gctctgcctt agacgacgtg   3840

ttacagtatg aacacacagc agaggcaccc tcgtatgttt tgaaagttgc cttctgaaag   3900

ggcacagttt taaggaaaag aaaaagaatg taaaactata ctgacccgtt ttcagtttta   3960

aagggtcgtg agaaactggc tggtccaatg ggatttacag caacattttc cattgctgaa   4020

gtgaggtagc agctctcttc tgtcagctga atgttaagga tggggaaaaa gaatgccttt   4080

aagtttgctc ttaatcgtat ggaagcttga gctatgtgtt ggaagtgccc tggttttaat   4140

ccatacacaa agacggtaca taatcctaca ggtttaaatg tacataaaaa tatagtttgg   4200

aattctttgc tctactgttt acattgcaga ttgctataat ttcaaggagt gagattataa   4260

ataaaatgat gcactttagg atgtttccta tttttgaaat ctgaacatga atcattcaca   4320

tgaccaaaaa ttgtgttttt ttaaaaatac atgtctagtc tgtcctttaa tagctctctt   4380

aaataagcta tgatattaat cagatcatta ccagttagct tttaaagcac atttgtttaa   4440

gactatgttt ttggaaaaat acgctacaga attttttttt aagctacaaa taaatgagat   4500

gctactaatt gttttggaat ctgttgtttc tgccaaaggt aaattaacta aagatttatt   4560

caggaatccc catttgaatt tgtatgattc aataaaagaa aacaccaagt aagttatata   4620

aaataaattg tgtatgagat gttgtgtttt cctttgtaat ttccactaac taactaacta   4680

acttatattc ttcatggaat ggagcccaga agaaatgaga ggaagccctt ttcacactag   4740

atcttatttg aagaaatgtt tgttagtcag tcagtcagtg gtttctggct ctgccgaggg   4800

agatgtgttc cccagcaacc atttctgcag cccagaatct caaggcacta gaggcggtgt   4860

cttaattaat tggcttcaca aagacaaaat gctctggact gggatttttc ctttgctgtg   4920

ttgggaatat gtgtttatta attagcacat gccaacaaaa taaatgtcaa gagttatttc   4980

ataagtgtaa gtaaacttaa gaattaaaga gtgcagactt ataattttca              5030


<210>  791
<211>  1464
<212>  DNA
<213>  Human

<400>  791
cgaagcactg gagagtgtca tggaggccta cgagcaggtc caaaagggac ccctgaagct     60

gaaaggcgtc gcagagctgg gagtgaccaa gcggaagaag aaaaagaagg acaaagacaa    120

agcgaaactc ctggaagcaa tgggaacgag caaaaagaac gaggaggaga agcggcgcgg    180

cctggacaag cggaccccgg cccaggcggc cttcgagaaa atgcaggaga agcggcaaat    240

ggaaaggatc ctaaagaagg catccaaaac ccacaagcag agagtggagg acttcaacag    300

acacctggac acactcacgg agcattacga cattcccaaa gtcagctgga cgaagtagcc    360

gcctgccccc agtatggagc agcatcgagg gttcgcaaaa ggccacactg gggttgtgtg    420

tgtttccttt ggtatattct ggaaacatgg ctacacacac ccttgcatct tctgctacag    480

actgcttttc gaagctgtgt accctcattc tggaacttga ttaaagtaag atcgtccttg    540

tactcagttt aggcttcttg gcaacataca gaagatacac ccttttcgtt tggatggaaa    600

gtttctaagt ttatccagag gtaaagccca ttgtgtgtct gtgtcatgta aaaatgtttt    660

cacccgagtt gcatgtaatg ctctgaggcc agccagctgt cttctcctgg atgagacaga    720

ctccagaggg taaggagcta gcgccatggt ggcctgcagt atgcagagcc ccgcaggacc    780

cagcgtgggc gcccttccaa gcttcctcta gctttgggcc tatgctgtcc cctgcaggcc    840

ctagggaagc cacttgcaac tatgcggcct tcagacttcc tcctcagcca cctggccact    900

gagacagcat agcctgggta acggaacagc cacctaaggc aagaatggaa cggacacacc    960

ttgctccttt ctgagcccgt ttcccaaaac cccccttcca ggtgcttcta atgggtgttg   1020

ccatagcaga cgctgctaat gcatcacagc attctttgaa atggaaccag acacagcctg   1080

cctctcaatc ctcagctggg ggctcctagc agcctcttgt atttactcag agttgacaca   1140

tcacacagat cctgtttggc attcctacct tacggacgtc tcaggggtga caggaccagg   1200

gcagagcccc ggtacaaaca gacaaggctg cagtcaaatg ggagggtcca ggtgtccgtg   1260

ttggagggct gggatcttgt agggcctgtg cgtcctggct gaggatcaaa ccacatatgt   1320

tattgggaga aacgatttct gttgacgtag atattgaaag aataatgaag gcagaagaga   1380

aaaacgaagt gtggaatttg gggttgtcct gtgtaaatta cacaataaag caaaagtcag   1440

ttattgtaaa aaaaaaaaaa aaaa                                          1464


<210>  792
<211>  7048
<212>  DNA
<213>  Human

<400>  792
gcgggtggtg ccggtggcgg cggcggggga gcgcgggaca ggaggcttcg gggaagatgg     60

acccggcgcc ctcgctgggc tgcagcctca aggatgtgaa gtggagctcg gtggccgtgc    120

cgctcgacct cctggtcagc acttaccggc tgccccagat cgcgcgcctg gacaacggag    180

agtgcgtaga agggctgcgg gaaaatgact atctgctgat tcattcctgc cgccagtgga    240

ccaccatcac tgcccacagc ttggaggagg gtcactatgt cattgggcca aagatagaga    300

ttccggtaca ttatgcaggg caattcaagc tgctggaaca agaccgagat ataaaggagc    360

cagtgcaata tttcaacagt gtggaggagg tggctaaggc atttcctgaa cgcgtgtacg    420

tcatggagga tatcacattc aacgtgaagg ttgcttcagg tgaatgcaat gaagacactg    480

aagtttacaa catcaccctg tgtactgggg atgaactcac tctaatgggg caggcagaaa    540

tcctttatgc aaagacattc aaggaaaagt cacgactcaa cacaatcttc aaaaagattg    600

ggaagctcaa ttccatcagc aagctgggaa aaggcaaaat gccgtgcctc atttgtatga    660

atcaccggac caacgaaagc attagccttc cattccagtg caagggcaga tttagcaccc    720

gaagtcccct ggaacttcag atgcaagagg gcgaacacac catccgcaac attgtggaga    780

aaaccaggct tcctgtgaat gtgactgtgc caagccctcc accgagaaac ccatacgacc    840

tccacttcat ccgtgagggg caccgctata agtttgtgaa catccagacc aagacggtgg    900

tggtttgctg tgtgctgcgg aacaacaaga tcctccccat gcactttcct ttgcacttga    960

ctgtccccaa gttcagcctc ccagaacacc tggtgaaggg agagagctgg cccgaaaccc   1020

tggtccatca ctggctaggt atctgccaag aacagttcga catcgatgag tattcacggg   1080

ctgtccgtga tgtgaaaacc gactggaatg aagaatgcaa gagccccaag aagggtcggt   1140

gctctggcca caaccacgtg cccaattcgc tcagctacgc ccgcgatgag ctcacccagt   1200

ccttccaccg actctcggtc tgtgtgtatg gcaacaatct ccatggcaac agtgaggtga   1260

accttcatgg ttgcagggac ctggggggag attgggctcc ctttcctcat gacatcctgc   1320

cctatcagga ctctggagat agtgggagcg actacctttt cccagaagct agtgaagaat   1380

cagcaggcat cccgggaaag tcagaacttc cctacgaaga gctgtggctg gaggaaggca   1440

agcccagcca tcagcctctc actcgctctc tgagcgagaa gaacagatgt gatcagttta   1500

gaggttctgt ccgatccaaa tgtgcgactt ctcctcttcc catccctggg actctgggag   1560

cagcagtgaa gtcttcagat actgccctac ctccacctcc agtgcctccc aaatctgaag   1620

ccgtcagaga agaatgccgg ctcctgaacg ccccacctgt tccaccccga agcgcaaagc   1680

ctttgtccac cagtccctcc atccctcctc gcacagtcaa gccagcgcgg caacagactc   1740

gctctcccag ccccaccttg tcctactatt cttcagggct acacaacatc gtcactaaaa   1800

ctgacacaaa tccttctgaa agcactcctg tttcctgcta tccatgtaac cgagtgaaaa   1860

ctgattctgt ggacctgaaa tccccgtttg gaagtccttc tgctgaagct gtgtcctctc   1920

ggctctcatg gcctaaccat tattcaggag catcagaaag ccagaccagg agtgacttcc   1980

tgctggatcc aagcaggagt tatagttacc ctagacaaaa gacgccaggc acaccaaaga   2040

gaaactgccc agcacctttt gattttgatg gctgtgagct cctggccagc cccactagcc   2100

cagtcactgc agaattcagt agcagcgtct ctggttgtcc caagtcagcc agctactctc   2160

tggagagcac agatgtgaaa tctcttgcag ctggtgtgac aaagcagagt acgtcatgcc   2220

ctgccttacc ccccagggct ccaaaactag tggaagagaa ggtcgcctcc gaaacatctc   2280

ctttgcctct gaaaattgat ggtgctgagg aagaccccaa gtctgggtca ccagatctct   2340

cggaggacca gtattttgtt aaaaagggca tgcaggacat cttctctgcc tcctaccctt   2400

tctcatctcc gctccatctc cagctggccc ccagatcctg tggcgacggt tccccatggc   2460

agccacctgc tgacctatca ggactctcta tagaggaagt gtccaagtca ctacggttca   2520

ttggtttgtc cgaagatgtc atatcattct ttgttactga aaagattgat gggaacctgc   2580

ttgttcagct aacggaagaa atcctctcag aggatttcaa attgagcaaa ttgcaggtga   2640

agaagataat gcaattcatt aatggctgga ggcccaaaat atagccaaat aacccccggc   2700

cagcatggaa caaaactgat caatgcgtgt gctagaaggg gtgggctggg acacaatttc   2760

atgtttttgc actaaaaacc ttctctgtaa atagggataa gagaaactct tactatgcag   2820

attacgtttt tgaatggtga acaggctatt ttgtacatca ataaaaatgc tgtacagaac   2880

acttggaggt gtgccttgta cgtcactcaa caaacactca gcagctgcta aaagaaaaaa   2940

aggcatgtgc agagaaatca ttcttaccca agtaggttta tgtgagaagg tatgatattt   3000

attacaaaat agccaaagct ggaagacata aaaatcttta aaaaaaaaaa aaaaacactt   3060

ttgaacaagt cccttctttc aggagggttg actttagaca attaactgtg ttctgtgctc   3120

tgtcattcag attgcttctt gctaattgtt ttactcttgt gcctgaaaat gttagtgata   3180

cgaattgaca ctttaatgtt gtatgcttgg tggggatctt tttatcacaa ggcattttcc   3240

aagagtcata tgttgataaa gggatatatg ttgtccttag aaatcacaca aatcatgacc   3300

acaataattt atctgtaact gctgctaatt ttattgagca gagaaaaaag aatatacata   3360

tataaacatg tataggtgca tacacaatac acccggatat gttttacaca taattttgat   3420

tctgatattt tagataacat ctgttcactt ttaaacaatc tgttgaggtt ttgggactgt   3480

tatctacatt gattctctta ggaatagtgg acagaatgac tccaaagatt ctcagaaccc   3540

tgtctcttga agctcaatct tatttgggtt catcactgaa aacttagaac aaatcagtaa   3600

agaatcctgt attgaagaat taagtttgag tttaagccca ctcaccgcag ggctggtttt   3660

tgcatgtaat actcccatga tgtctgggga aatgacagtt tctgttgaat tataattctc   3720

cggtttaagg gtctccttcc cctggtgtct gatggtgaga ggtctgaaga gcatttgtca   3780

gagtacatta ggcattctca acctacttca tgctttacga gagctgagaa atcagacgca   3840

ccggccttta ttattatata tgctacatct gttgagtatt tttaaaatac caataagagg   3900

acttgtttat ttcataaacc acttcttccc tctctttcaa agaaaataca ttattaccat   3960

acttttacat tagtctgaga atttttgcta aatatgatta agtattccaa aatataatgg   4020

cgtcattatt cttgactttt ttagagaata tacatcttaa gactgtatta gttctcagag   4080

caaggcatca tctactcccc tgcacctgag agtctggccc cagattccag atgtgcggac   4140

agcccatgac cgaggtgcac acagtgccct cttgaatagg aaggtcagcc agtgaggcgg   4200

cagcataact tgcaggatgg acttatatct taccatctct tcctgctacc aaaataaaaa   4260

aataaattga aagacaagac ccaccagtct agttttgtag acctgtgaaa tgtgtcttta   4320

tttcttggca ttagaagaaa gatattttta atccatatcg tggttttaga gttgaagtga   4380

attgataccc aattttccat cttagatctc ctttatcaaa aaaaaaagca ttttttttct   4440

cctaacgtgt ctcccaaaat gtaaatacta taggcaaaaa gagtaccctg taaaattctc   4500

acactggagc acctcttcaa aagtcacaga taactcaatg aggaagtgct ggtactgcac   4560

tcacaggaca tgagacctat gaagctttcg tgttttgaaa gcatccttct gtgtgagggg   4620

gactgcctcc cttagtaaag taaacctctc agaacttctt tttaaaataa aaacagacaa   4680

gatgcagtta ctaagctgca agttttcatt ggcaaaccta gctgaatccg ttttaaaata   4740

cttagcactc ggacacaatt ctcaaactca ggaagaagga acagggttgg tttgggttta   4800

ctataaaggt tgcctcacat aaacaactga ctccttttag cgtttttttt ctttttgtaa   4860

aaactttaca caaaataggg ttttaaattc tttttgcttg ttttggactt ggtgtatttt   4920

tgtcaagttt atattgattg gcaacgcaga gactccttga gggcagggac tgtggccttt   4980

gattcactta tgctacagtc tagtatcact acagtgctga gtaaaagaca cagcccctgc   5040

cctcttggag atcatattgt ttatatttga aatctcagtt gctaagagta tgtatgtgtg   5100

agtaagaaag acgtgaagtc ctatgggcag ctgggtatat ggagaattac gtgtgtcctg   5160

tctttaaaac gtcagcctct attaaggggt acagaacacc ccaagatcac taaaacttgg   5220

aatgtgttgg aggcagaaag tatctctctc attgcctagt gttgttgttt ttttgttttt   5280

tgttttttgt tttttttact gacctggaat tcttttaatt gtaataaata tcttctgtca   5340

caaataaatg ccacaaataa atgaaattgc cattcctaag ctgagcacct gtctgtgaag   5400

gaccttggtg tcctgactgg acagagcatt catagctcca agagaatcat gacaagatat   5460

gcaaagcagg gataataagg agaaagccct tccctttcga gaagcccttc cctttcacag   5520

cccttccctg cgattctgca gtgaaaagtg atgcccagag atccacacac agaacccttc   5580

taaccagcca ggtcaagact tatcatctta tctcctctgg caggtcccct gtaatcaaaa   5640

gagaggaagt gtctatctaa acaagaccct tttgggtcct tagattcatg gcaaaaatca   5700

tcatggcccc catcagaaaa gaaaatcagc aataaaccaa gccaagcaac taaaatgtat   5760

aatgtggacc tgactcatgt tgggaggcag aattcagaca ctcacagatc aatcttgcaa   5820

gttttctctt ctttaagttg agctgctcaa ctttatgaac tgtgaaattt acttacattc   5880

tttcaaccca catatatcat tgcagtttat gaagttgcag tgaactgccc attcagctaa   5940

attgcagtgt ttattcttgt ctcatgtcga aatacaacaa tcttatggga aatattatga   6000

cagtccgttc caactgttct cagacacatg cataaacagt ctctgctcac attccacagc   6060

cacctgcatg ttatccatac agctccctga gaagtccagg gatgggaggt ggggtgtgga   6120

aggatggagg gtccttcatt ttctaaacac tttgtataag tcactactca tcgtgcctag   6180

caagtataag attaacattt tgaataacaa actggaaaac aaataatcct tcaaagaacc   6240

tagcgaactg ttcaaaggaa attttaattt cagtctacca gaaaagttaa atctgttgtt   6300

ggacgtaggg ggctttcaga aacatgcctc ttatatcaat ttccactatc tttcaagtta   6360

cctaaaggca ccaggctgct tgagcaagaa gaataaaagg cctagagtgc aaattatgtg   6420

aagtagagtt tttagattgt gggattgtaa taatacggga ttctcatggt tacatcatgt   6480

taaatcacac tgttcagtct ttaaaacttg gtgttttaaa atttgtctca ttgtgatagc   6540

cagaaacaag gaataaacgt gatttcagtt taaactatat acaaatatct tctgtaattt   6600

tgctgctcta atttttaggc tataaatttt gtaatagagc ttatcagatc gcaaatttcc   6660

tttgtttaca atctcatgta gtagggctca gataatttct tagctataaa ccttttctcc   6720

cactctcata ttgtttcatt taaaatattt aagctaagcc taaaaattga aatcagttaa   6780

gaatttggag agtttatctt aaatggaaat ggtgtattct tttcaaagaa ttttgtaacc   6840

atctttacag tttctttgct tggaaaactt gggttgttaa ctaccagtta acaatggcat   6900

tactttccaa aacgttatct aatgggccca atgtgtacct caagataaac acagtatgtt   6960

atgtctaaaa atttccttgt ctgttgattt aaatggttct gaaatgtctg taataaagaa   7020

attttcaaag ttgcaaaaaa aaaaaaaa                                      7048


<210>  793
<211>  973
<212>  DNA
<213>  Human

<400>  793
gacgcgtggg cggtgaagga ggagtgccgc ctgctcaatg cccctccagt gcctcctcgg     60

ggtggcaatg gcagcggccg gctctccagc agccccccgg ttccccctcg cttccccaag    120

ctgcagccgg tacattcccc cagctccagc ctctcctact actcctctgg cctccaggat    180

ggggcgggtt cccgcagtgg cagtggctcc ccatcgccgg acacctactc cctctattgc    240

tacccatgca cctggggaga ctgcaaggaa ccagtcctgg agcccttcga tccctttgag    300

ctggggcagg gcagttctcc agagcctgag ctgctgcgtt ctcaggagcc cagagcagtg    360

gggacacctg ggcctggacc ccgcctttca ccacttggcc cctccaaggc ctttgagcct    420

gaaggtttgg tgctgcacca ggtccccacc ccactgtcac cagctgctct gcagggaccc    480

gaggcgggag gagcactttt tctaacccaa gggcgcctgg aagggcctcc tgccagtccc    540

cgggatggag ccacaggctt tggagtccga gatgcctcct cctggcagcc ccctgctgac    600

ctgtctgcac tctccctgga ggaggtctct cgcagtctgc gtttcatcgg gctctcagag    660

gatgtggtga gcttctttgc ccgagaacgc atcgatggta gcatctttgt gcagctcagt    720

gaggacatcc tggcagatga cttccacctc accaagctgc aggtcaagaa gatcatgcag    780

ttcatcaaag gctggaggcc caagatctga actgcccagc tggagctgca cagctggaat    840

gctggtatgg gggccccagg tacagcactc cggaggagca ggtgctgcct gcaagaagga    900

tctatgtcga gactgaggct gctcagcagc cactgggtgg atccagggga gatgcatgtg    960

gaaatgtggt cct                                                       973


<210>  794
<211>  2558
<212>  DNA
<213>  Human

<400>  794
ccgccctgct cgtgataagg cacaagcaag ggctgccctg aaggaagctc caaagagaaa     60

ggagggcagg aagcccacgg cccacagggg tgtagcccga gacccacctg cagcccccag    120

cccttgccag gaaagcagca gccgcagcca tggcggggat gaagacagcc tccggggact    180

acatcgactc gtcatgggag ctgcgggtgt ttgtgggaga ggaggaccca gaggccgagt    240

cggtcaccct gcgggtcact ggggagtcgc acatcggcgg ggtgctcctg aagattgtgg    300

agcagatcaa tcgcaagcag gactggtcag accatgctat ttggtgggaa cagaagaggc    360

agtggctgct gcagacccac tggacactgg acaagtacgg gatcctggcc gacgcacgcc    420

tcttctttgg gccccagcac cggcccgtca tccttcggtt gcccaaccgc cgcgcactgc    480

gcctccgtgc cagcttctcc cagcccctct tccaggctgt ggctgccatc tgccgcctcc    540

tcagcatccg gcaccccgag gagctgtccc tgctccgggc tcctgagaag aaggagaaga    600

agaagaaaga gaaggagcca gaggaagagc tctatgactt gagcaaggtt gtcttggctg    660

ggggcgtggc acctgcactg ttccggggga tgccagctca cttctcggac agcgcccaga    720

ctgaggcctg ctaccacatg ctgagccggc cccagccgcc acccgacccc ctcctgctcc    780

agcgtctgcc acggcccagc tccctgtcag acaagaccca gctccacagc aggtggctgg    840

actcgtcgcg gtgtctcatg cagcagggca tcaaggccgg ggacgcactc tggctgcgct    900

tcaagtacta cagcttcttc gatttggatc ccaagacaga ccccgtgcgg ctgacacagc    960

tgtatgagca ggcccggtgg gacctgctgc tggaggagat tgactgcacc gaggaggaga   1020

tgatggtgtt tgccgccctg cagtaccaca tcaacaagct gtcccagagc ggggaggtgg   1080

gggagccggc tggcacagac ccagggctgg acgacctgga tgtggccctg agcaacctgg   1140

aggtgaagct ggaggggtcg gcgcccacag atgtgctgga cagcctcacc accatcccag   1200

agctcaagga ccatctccga atctttcggc cccggaagct gaccctgaag ggctaccgcc   1260

aacactgggt ggtgttcaag gagaccacac tgtcctacta caagagccag gacgaggccc   1320

ctggggaccc cattcagcag ctcaacctca agggctgtga ggtggttccc gatgttaacg   1380

tctccggcca gaagttctgc attaaactcc tagtgccctc ccctgagggc atgagtgaga   1440

tctacctgcg gtgccaggat gagcagcagt atgcccgctg gatggctggc tgccgcctgg   1500

cctccaaagg ccgcaccatg gccgacagca gctacaccag cgaggtgcag gccatcctgg   1560

ccttcctcag cctgcagcgc acgggcagtg ggggcccggg caaccacccc cacggccctg   1620

atgcctctgc cgagggcctc aacccctacg gcctcgttgc cccccgtttc cagcgaaagt   1680

tcaaggccaa gcagctcacc ccacggatcc tggaagccca ccagaatgtg gcccagttgt   1740

cgctggcaga ggcccagctg cgcttcatcc aggcctggca gtccctgccc gacttcggca   1800

tctcctatgt catggtcagg ttcaagggca gcaggaaaga cgagatcctg ggcatcgcca   1860

acaaccgact gatccgcatc gacttggccg tgggcgacgt ggtcaagacc tggcgtttca   1920

gcaacatgcg ccagtggaat gtcaactggg acatccggca ggtggccatc gagtttgatg   1980

aacacatcaa tgtggccttc agctgcgtgt ctgccagctg ccgaattgta cacgagtata   2040

tcgggggcta cattttcctg tcgacgcggg agcgggcccg tggggaggag ctggatgaag   2100

acctcttcct gcagctcacc gggggccatg aggccttctg agggctgtct gattgcccct   2160

gccctgctca ccaccctgtc acagccactc ccaagcccac acccacaggg gctcactgcc   2220

ccacacccgc tccaggcagg cacccagctg ggcatttcac ctgctgtcac tgactttgtg   2280

caggccaagg acctggcagg gccagacgct gtaccatcac ccaggccagg gatgggggtg   2340

ggggtccctg agctcatgtg gtgccccctt tccttgtctg agtggctgag gctgataccc   2400

ctgacctatc tgcagtcccc cagcacacaa ggaagaccag atgtagctac aggatgatga   2460

aacatggttt caaacgagtt ctttcttgtt actttttaaa atttcttttt tataaattaa   2520

tattttattg ttggatcctc aaaaaaaaaa aaaaaaaa                           2558


<210>  795
<211>  4336
<212>  DNA
<213>  Human

<400>  795
agttcgccct gccggaaagc agcacgccgc cgcggcattt tacgacgtcg gcggtgacag     60

gccctgggac tctgggaata cccagcttcc tccccgcaac ccggtgaaag ccaacgcaat    120

gttcggtgcg ggggacgagg acgacaccga tttcctctcg ccgagcggcg gtgccagatt    180

ggcctcactt tttggactgg atcaggcagc tgctggccat ggaaatgaat ttttccagta    240

cacagcccca aaacagccta agaaaggcca gggaacggca gcaacaggaa atcaggcaac    300

accaaaaaca gcaccagcca ccatgagcac tcccacaata ctggtcgcaa cagcagtcca    360

tgcatatcga tacacaaatg gtcaatatgt aaagcagggc aaatttggtg ctgcagttct    420

ggggaaccac acagccagag agtataggat tcttctttat atcagtcaac aacagccagt    480

tacggttgct aggattcatg tgaactttga gctaatggtt cggcccaata actatagcac    540

cttttatgat gaccagagac agaactggtc catcatgttt gagtcggaaa aggctgctgt    600

ggagttcaat aagcaggtgt gcattgctaa gtgcaacagt acctcttccc tggatgcagt    660

gctctcccag gacctcattg tggcagacgg ccctgctgta gaagttggag attctttgga    720

agtggcctat accggctggc tctttcagaa tcatgtgctg ggccaggttt tcgactccac    780

tgctaacaaa gataagttgc ttcgcttgaa gttaggatca ggaaaagtca tcaagggctg    840

ggaggatgga atgctgggca tgaaaaaagg aggaaagcga ttgcttattg tccctccagc    900

ctgtgctgtt ggctcagaag gggtaatagg ctggactcaa gcaacggact cgatcctggt    960

gttcgaggtg gaggttaggc gggtgaagtt tgccagagat tctggctctg atggtcacag   1020

tgttagttcc cgcgattctg cagctccgtc tcccatccct ggtgctgaca acctctctgc   1080

tgatcctgtt gtgtcaccac ccacatcaat acctttcaaa tcaggggagc cagctcttcg   1140

taccaaatct aactccctca gtgaacaact tgcaataaat acaagtcccg atgcagtcaa   1200

agccaagttg atctctcgga tggctaaaat gggccagccc atgctgccca tccttccacc   1260

acagctggat tccaatgatt cagaaatcga agatgtgaac actctgcaag gaggtgggca   1320

gcctgtggtg actccgtccg tccagccctc tcttcatccg gcccatccag cgttaccaca   1380

gatgacctca caggcacctc agccatctgt tactgggctc caggcacctt ctgctgcctt   1440

aatgcaagtg tcatctctcg attcccactc agctgtatct ggaaatgccc aatcctttca   1500

gccctatgca ggtatgcaag cctacgctta tccccaggca tctgccgtca cctcccagct   1560

gcagcccgtt cggcctttgt acccagcacc gctctctcag cctccccatt tccaaggatc   1620

aggtgatatg gcttcatttc tcatgactga agcccggcaa cataacactg aaattcgaat   1680

ggcagtcagc aaagtggctg ataaaatgga tcatctcatg actaaggttg aagagttaca   1740

gaaacatagt gctggcaatt ccatgcttat tcctagcatg tcagttacaa tggaaacaag   1800

catgattatg agcaacatcc agcgaatcat tcaggaaaat gaaagattga agcaagagat   1860

ccttgaaaag agcaatcgga tagaagaaca gaatgacaag attagtgaac taattgaacg   1920

aaatcagagg tatgttgagc agagtaacct gatgatggag aagaggaaca actcacttca   1980

gacagccaca gaaaacacac aggcaagagt attgcatgct gaacaagaga aggccaaggt   2040

gacagaggag ttagcagcgg ccactgcaca ggtctctcat ctgcagctga aaatgactgc   2100

tcaccaaaaa aaggaaacag agctgcagat gcagctgaca gaaagcctga aggagacaga   2160

tcttctcagg ggccagctca ccaaagtgca ggcaaagctc tcagagctcc aagaaacctc   2220

tgagcaagca cagtccaaat tcaaaagtga aaagcagaac cggaaacaac tggaactcaa   2280

ggtgacatcc ctggaggagg aactgactga ccttcgagtt gagaaggagt ccttggaaaa   2340

gaacctctca gaaaggaaaa agaagtcagc tcaagagcgt tctcaggccg aggaggagat   2400

agatgaaatt cgcaagtcat accaggagga attggacaaa cttcgacagc tcttgaaaaa   2460

gactcgagtg tccacagacc aagcagctgc agagcagctg tctttagtac aggctgagct   2520

acagacccag tgggaagcaa aatgtgaaca tttgttggcc tccgccaagg atgagcacct   2580

gcagcagtac caggaggtgt gcgcacagag agatgcctac cagcagaagc tggtacaact   2640

tcaggaaaag tgtttagccc tccaggccca aatcacagct ctcaccaagc aaaatgaaca   2700

gcacatcaag gaactagaga agaacaagtc ccagatgtct ggggttgaag ctgctgcatc   2760

tgacccctca gagaaggtca agaagatcat gaaccaggtg ttccagtcct tacggagaga   2820

gtttgagctg gaggaatctt acaatggcag gaccattctg ggaaccatca tgaatacgat   2880

caagatggtg actcttcagc tgttaaacca acaggagcaa gagaaggaag agagcagcag   2940

tgaagaagaa gaagaaaaag cagaagagcg gccacgaaga ccttcccagg agcagtcagc   3000

ctcagccagt tctgggcagc ctcaagcacc cctgaatagg gagaggccag agtcccccat   3060

ggtgccctca gagcaggtgg tcgaggaagc tgtcccgttg cctcctcagg ccctcaccac   3120

ttcccaggat ggacacagaa ggaaagggga ctcagaagct gaggcactct cagagataaa   3180

agatggttcc cttccacccg aactgtcttg catcccatcc cacagagttc tagggccccc   3240

gacttcaatt ccacctgagc ccctaggccc tgtatccatg gactctgagt gtgaggagtc   3300

acttgctgcc agcccaatgg cagctaagcc cgacaaccca tcaggaaagg tctgtgtcag   3360

ggaagtagca ccagatggcc cactacaaga aagctccaca agactgtccc tgacttcaga   3420

ccccgaggag ggggacccac tggccttagg gcctgaaagc ccaggagagc ctcagcctcc   3480

acagctcaag aaagatgatg tcactagctc caccggtccc cacaaggagc tgtcaagcac   3540

agaggcaggt tccacagttg caggagcagc cctcagaccc agccatcatt cccagcgttc   3600

cagtctctct ggggatgaag aggatgaact gtttaaaggg gcaactctga aagctctgag   3660

gcccaaagca cagcctgagg aggaggatga agacgaggtg agcatgaagg gacgcccgcc   3720

cccaacgccc ctttttggag atgatgatga tgacgatgac attgactggc tgggatgaag   3780

acccaggaaa ctggtgcaaa ggtttctctg caacccttcc ctaagcatga ttttgcacag   3840

ccaaccctgg gtctaggcga accacagggt gaggtcaagg tgagcattct gggaacaata   3900

tttgggctca gagggtgggt tggccacctt ctgagcccca cccccgccag acctggtgaa   3960

gaggatcata accctgtctt caagaacact gggatttcag cagcaagttg gaagaaggac   4020

tggtaggttc ccctccaagc cagtcacctg taagagtcct gtcctctgcc agacttttta   4080

atctcttcat taactctcag actgacctgg gagccctcct ctacctgaat ccagtgctca   4140

actgtgcccc ggcaacaaga cctgggctga ggtctccctg gtagaactaa gggagattac   4200

accatctaaa tcccagtgca gtcaacagcc tggcctatag tcctgggaca tgtatcttct   4260

tctttgcctt aaatctgata caagaggtca atgactttga aaataaaact aaaataaatg   4320

tctataatga aacttg                                                   4336


<210>  796
<211>  3097
<212>  DNA
<213>  Human

<400>  796
atcgccagtc tagcccactc cttcataaag ccctcgcatc ccaggagcga gcagagccag     60

agcaggatgg agaggagacg catcacctcc gctgctcgcc gctcctacgt ctcctcaggg    120

gagatgatgg tggggggcct ggctcctggc cgccgtctgg gtcctggcac ccgcctctcc    180

ctggctcgaa tgccccctcc actcccgacc cgggtggatt tctccctggc tggggcactc    240

aatgctggct tcaaggagac ccgggccagt gagcgggcag agatgatgga gctcaatgac    300

cgctttgcca gctacatcga gaaggttcgc ttcctggaac agcaaaacaa ggcgctggct    360

gctgagctga accagctgcg ggccaaggag cccaccaagc tggcagacgt ctaccaggct    420

gagctgcgag agctgcggct gcggctcgat caactcaccg ccaacagcgc ccggctggag    480

gttgagaggg acaatctggc acaggacctg gccactgtga ggcagaagct ccaggatgaa    540

accaacctga ggctggaagc cgagaacaac ctggctgcct atagacagga agcagatgaa    600

gccaccctgg cccgtctgga tctggagagg aagattgagt cgctggagga ggagatccgg    660

ttcttgagga agatccacga ggaggaggtt cgggaactcc aggagcagct ggcccgacag    720

caggtccatg tggagcttga cgtggccaag ccagacctca ccgcagccct gaaagagatc    780

cgcacgcagt atgaggcaat ggcgtccagc aacatgcatg aagccgaaga gtggtaccgc    840

tccaagtttg cagacctgac agacgctgct gcccgcaacg cggagctgct ccgccaggcc    900

aagcacgaag ccaacgacta ccggcgccag ttgcagtcct tgacctgcga cctggagtct    960

ctgcgcggca cgaacgagtc cctggagagg cagatgcgcg agcaggagga gcggcacgtg   1020

cgggaggcgg ccagttatca ggaggcgctg gcgcggctgg aggaagaggg gcagagcctc   1080

aaggacgaga tggcccgcca cttgcaggag taccaggacc tgctcaatgt caagctggcc   1140

ctggacatcg agatcgccac ctacaggaag ctgctagagg gcgaggagaa ccggatcacc   1200

attcccgtgc agaccttctc caacctgcag attcgagaaa ccagcctgga caccaagtct   1260

gtgtcagaag gccacctcaa gaggaacatc gtggtgaaga ccgtggagat gcgggatgga   1320

gaggtcatta aggagtccaa gcaggagcac aaggatgtga tgtgaggcag gacccacctg   1380

gtggcctctg ccccgtctca tgaggggccc gagcagaagc aggatagttg ctccgcctct   1440

gctggcacat ttccccagac ctgagctccc caccacccca gctgctcccc tccctcctct   1500

gtccctaggt cagcttgctg ccctaggctc cgtcagtatc aggcctgcca gacggcaccc   1560

acccagcacc cagcaactcc aactaacaag aaactcaccc ccaaggggca gtctggaggg   1620

gcatggccag cagcttgcgt tagaatgagg aggaaggaga gaaggggagg agggcggggg   1680

gcacctacta catcgccctc cacatccctg attcctgttg ttatggaaac tgttgccaga   1740

gatggaggtt ctctcggagt atctgggaac tgtgcctttg agtttcctca ggctgctgga   1800

ggaaaactga gactcagaca ggaaagggaa ggccccacag acaaggtagc cctggccaga   1860

ggcttgtttt gtcttttggt ttttatgagg tgggatatcc ctatgctgcc taggctgacc   1920

ttgaactcct gggctcaagc agtctaccca cctcagcctc ctgtgtagct gggattatag   1980

attggagcca ccatgcccag ctcagagggt tgttctccta gactgaccct gatcagtcta   2040

agatgggtgg ggacgtcctg ccacctgggg cagtcacctg cccagatccc agaaggacct   2100

cctgagcgat gactcaagtg tctcagtcca cctgagctgc catccaggga tgccatctgt   2160

gggcacgctg tgggcaggtg ggagcttgat tctcagcact tgggggatct gttgtgtacg   2220

tggagaggga tgaggtgctg ggagggatag aggggggctg cctggccccc agctgtgggt   2280

acagagaggt caagcccagg aggactgccc cgtgcagact ggaggggacg ctggtagaga   2340

tggaggagga ggcaattggg atggcgctag gcatacaagt aggggttgtg ggtgaccagt   2400

tgcacttggc ctctggattg tgggaattaa ggaagtgact catcctcttg aagatgctga   2460

aacaggagag aaaggggatg tatccatggg ggcagggcat gactttgtcc catttctaaa   2520

ggcctcttcc ttgctgtgtc ataccaggcc gccccagcct ctgagcccct gggactgctg   2580

cttcttaacc ccagtaagcc actgccacac gtctgaccct ctccacccca tagtgaccgg   2640

ctgcttttcc ctaagccaag ggcctcttgc ggtcccttct tactcacaca caaaatgtac   2700

ccagtattct aggtagtgcc ctattttaca attgtaaaac tgaggcacga gcaaagtgaa   2760

gacactggct catattcctg cagcctggag gccgggtgct cagggctgac acgtccaccc   2820

cagtgcaccc actctgcttt gactgagcag actggtgagc agactggtgg gatctgtgcc   2880

cagagatggg actgggaggg cccacttcag ggttctcctc tcccctctaa ggccgaagaa   2940

gggtccttcc ctctccccaa gacttggtgt cctttccctc cactccttcc tgccacctgc   3000

tgctgctgct gctgctaatc ttcagggcac tgctgctgcc tttagtcgct gaggaaaaat   3060

aaagacaaat gctgcgccct tccccaaaaa aaaaaaa                            3097


<210>  797
<211>  1863
<212>  DNA
<213>  Human

<400>  797
agtgacgtca cggcccgtgg cgcccttcgt ggactgggct gtacggtgcg cgtgacggct     60

gcgtgcggcg ggaatcatgg ctgctcgcag agctctgcac ttcgtattca aagtgggaaa    120

ccgcttccag acggcgcgtt tctatcggga cgtcctgggg atgaaggttc tgcggcatga    180

ggaatttgaa gaaggctgca aagctgcctg taatgggcct tatgatggga aatggagtaa    240

aacaatggtg ggatttgggc ctgaggatga tcattttgtc gcagaactga cttacaatta    300

tggcgtcgga gactacaagc ttggcaatga ctttatggga atcacgctcg cttctagcca    360

ggctgtcagc aacgccagga agctggagtg gccactgacg gaagttgcag aaggtgtttt    420

tgaaaccgag gccccgggag gatataagtt ctatttgcag aatcgcagtc tgcctcagtc    480

agatcctgta ttaaaagtaa ctctagcagt gtctgatctt caaaagtcct tgaactactg    540

gtgtaatcta ctgggaatga aaatttatga aaaagatgaa gaaaagcaaa gggctttgct    600

gggctatgct gataaccagt gtaagctgga gctacagggc gtcaagggtg gggtggacca    660

tgcagcagct tttggaagaa ttgccttctc ttgcccccag aaagagttgc cagacttaga    720

agacttgatg aaaagggaga accagaagat tctgactccc ctggtgagcc tggacacccc    780

agggaaagca acagtacagg tggtcattct ggccgaccct gacggacatg aaatttgctt    840

tgtcggggat gaagcatttc gagaactttc taagatggat ccagagggaa gcaaattgtt    900

ggatgatgca atggcagcag ataaaagtga cgagtggttt gccaaacaca ataaacccaa    960

agcttcaggt taacggaaga catgatgcag agcaagcctc tgtgattcct gcccagcacc   1020

tgtgaggcct gacgtgtcag ttcccaataa atgctcttct gatttgtttc ccgtacaggc   1080

aaggaggctt gggtagtgca gatttgtgta tttcaatctt tgaaagctct gatgtaattt   1140

agaaatgaaa tccaatcatg agtccaggta gagaacgcct gctgtaatct acactgttgc   1200

tgggactgcg cattctgtat ataactgtgt tggatgagtg acagatgatt gtccagacta   1260

ggacagcggc atgaacatga ctttggttgg gattgcggat agttagggtt acctctgaat   1320

cgtgtagctt ttatgagagc agctgtgcaa gtgaatccac attaatgcct tgtcgtggtg   1380

ccattcccag cgcctgacga tacgctcttc tattgtctta ttctggcagg ttttgacgtt   1440

ttaaattttt taaagaaatt ttattccttg gaccaaaagg tttggttaac cacccccctc   1500

ttacttgctt tcacattttg agtgtccaga ggaaacagaa aggaatgagt gtgtgacgtt   1560

gctgcacgcc tgactctgtg cgagcttctt tctgtgtata tattttgttt tatttttttc   1620

cgtgtatatt tttaatcccg acagaacatc atgtgagatt tctttaaaat ggattaaacg   1680

atttcttcag cctgaaaaaa aaggttttga aaatgttttc ttgtagtttt gtttggttct   1740

aaacaacaaa taggttttaa tcactcgaaa tggaattata ttgtgtattc attgaataaa   1800

ttttttttga aagtaagctt ctgaaatcaa gctgtgaaaa aaaaaaaaaa aaaaaaaaaa   1860

aaa                                                                 1863


<210>  798
<211>  4139
<212>  DNA
<213>  Human

<400>  798
aagaagaccc cgttcttccg ggaaaatggc gactcccgct cgtgccccgg agtcaccgcc     60

gtccgcggat ccggcgctag tagcggggcc tgccgaggaa gccgagtgcc cgccgccgcg    120

ccagcctcag cccgcgcaga atgtgctcgc tgccccgcgg cttcgagccc caagctcccg    180

aggacttggc gcagcggagt ttggtggagc tgcgggaaat gttgaagcgc caggagagac    240

ttttgcgcaa cgaaaaattc atttgcaaat tgcccgacaa aggtaaaaag atctttgact    300

cttttgccaa actgaaagct gccattgcag aatgtgaaga agttagaaga aaaagtgaac    360

tgtttaaccc tgttagttta gactgtaagc taaggcaaaa agcaattgca gaagttgatg    420

tgggtacaga taaggcccag aattctgacc cgatacttga tacttcatca ctagttcctg    480

gatgttcctc tgtagataac atcaagtcat ctcaaacctc acaaaaccag ggacttggac    540

gtcctactct tgaaggtgat gaagagactt cagaggttga gtacacagtg aataagggcc    600

cagcttccag caatagagac agggtaccac cttcatctga agctagtgag catcacccgc    660

ggcatcgtgt ttcaagtcaa gcggaagata cttccagcag ctttgacaac ctgtttattg    720

acaggttaca gaggatcacc attgcggacc aaggtgaaca acagtcagaa gaaaacgcaa    780

gtactaagaa cttgacaggc ctttccagtg ggactgagaa gaaacctcat tacatggaag    840

tgctagaaat gcgagccaaa aacccagtgc cccagctgcg taaatttaaa accaatgtgt    900

taccttttcg acaaaatgat tcatctagtc attgccagaa gagtgggtct cctatttcct    960

cagaagagcg gcggcgcagg gataagcagc atcttgatga catcacagca gctcggcttc   1020

taccacttca ccatatgccc acgcagctgc tctccataga agaatccttg gcacttcaga   1080

aacagcagaa acagaattat gaggagatgc aagcaaagct cgcagcgcaa aaattagctg   1140

aaagactgaa tattaaaatg cggagttata atccagaagg ggagtcttca gggagatacc   1200

gagaagtaag ggatgaagat gacgattggt cctctgatga attctgaaga taatctccta   1260

aatcactgac gttgagatgt catcatctta catcagactt tctaactagt atcaagatca   1320

gtgtcagata ttgttgaggg aagtaatttt ataaagttac acaaaggtag ttataaaaaa   1380

agcccagttt gtctttcaga aggtgacttt catgtgcttg aaaagtttaa tatttgaata   1440

ttgtgtttaa ccacatggta ttaaaatttt gcaatatatt gtgtattggt ctgatatttt   1500

agtatatagt agaacatact ttttttttct ttaagccaaa tgaaaagagg taactttgct   1560

tttttccttt ttcttaccta tcaaatagca tttattacat gtctttcagt gaaatactta   1620

gttgttccag gcacctaaaa tcaattagga agacatagtt cccttctttt ttgggtaatg   1680

aagggagcag tctaaagaat tgtatgcatg tttgcatggg gttattgaga cattggatgt   1740

gaaataccta ggaagacatg tatggagaat gcttaacaaa tgctcttctc ctttttctgt   1800

cttcccttag gaagaacgtt atctctcttc tgattaggaa ggacttccct tttgagtaga   1860

tgctggaaag tggaggtttt ttttgttggt ttgtttgttt ggttttgtgt ttttttttga   1920

gatggggtct tgctctgtcg cccaggctgg agtgcagtgg caggatctcg gctcactgca   1980

atctaggtgg aggtcttttt aaataacctc atgttacttc aggcaaatct ggtacaggag   2040

aagcccaagc taactgagct gggtgaaggc ttgtgcatca cctggcttga gttccttgct   2100

gtcacagatg ataggttcat gtacacaaca ttaatgtttg ataaggaaag catttttttt   2160

ttgttaaaat tgaattgtca gtactttact tttttccccc caaataggta tatatagact   2220

gcagaagctt cagtcccata tataaacgtt catgtcattt tagaggatta tatggttgtc   2280

tccagagaaa ttaacttaca ttatcaaaaa attctttgtc taatatattg gagtctttaa   2340

aagtgttgaa gaataaaata ttaattagaa caacttcaaa tgctaaggtg atgttttacc   2400

gggacttaat taaatacaac tttttccttt cgaaaaagac tgttcacatt tgcttccagg   2460

tgtaattatt gctttcattc cttacccccc tcaagcaaat gtgaaaagta tactgaccta   2520

agattctcat tagttttagt tcttaaaacg aatagtaaat gatttcacag cgtaaaattt   2580

gatgttattt ctggaagctg gatgatatgg aagagttcat gtgcctggac acacagttcc   2640

ctgtaatcct gccatctagg gagataaact ctgttaacat tttgatgttg tgtttttgct   2700

tatttttcta tgcatagtta tgcatttata ttctcaaaaa tgaaatcata atgtacattg   2760

ctttgtagtc tgctctatat attgtcaata tgttcccata ttaaatattt tgctttttag   2820

acagctgtag gatattttat ttcatgggta taccataact ttaagattta tttcctattc   2880

agcaatttga ttatgtatta taatgtaatc tgtaaatagt gatatgatta acatcttaat   2940

cacatccata gaaaatgact tatttccaga agataccgct ctaaaaatga aattgttagg   3000

tgaaagtgtt tttgagaatt tttatatata ttactcactg cagagatcat gttcatttac   3060

attcccatta gcaatatatc caatgctcag aattgaaaat tactacttaa aatctttgca   3120

aattgaataa ttacagaaaa gggctacatt taaaatttgt atttgttttt cttacttagt   3180

gaaggttgtg ttttttttca tattcattgg ccatgctata ttcattcttt tgagaattgc   3240

tcattcatat tttttctgtt gcttgcttgg agaatttgct ctttttttgg catataagtt   3300

cttaagaatg tccgtccttt gtcatatatt gtaacttttt ttagccttat ttgtcattta   3360

acatagtttg tggtatttca gtatagaagt tgttttcttt aggagtctac ctttgtgtat   3420

gtgcttgaaa gtatttttgt aatccaagaa tggataaatg tccttatttt cttctagtat   3480

tttcttattt cacttttaca cctatcttta aaaggaattt aaattttgtt tatatacatt   3540

aactaaatca gtacaagttt ggggtgaaaa ggaaattttt aatccatctc aaatgtattt   3600

ggttatatta tataaggtag ggatttgatt ttatttcgaa gaatttacca attggttcag   3660

tatgtgaaac caccatttcc cctctgatta gtaatgctat ttttatagaa tattaaattc   3720

ttatgtgtct tttgtgtctt aggccaattt ctgggccttc tgggtttttt ctacactgtc   3780

aataattatc gctttaattg gtgttaatat ttggtagtac acaggttctc ccttgttctt   3840

ttaaattttg tgaaatataa cttacaaata agtacttaaa acagagctta atgggtaaag   3900

caacagctgt gtaatcacaa actagatgca gaggaggtct tgccagcact ccaaaatctc   3960

tgtgtgtccc ctcttgacac tcactgtttc ccccagagct aactatcctg acgtatggta   4020

attctccctc tgtcctttta agaattattt taccagttat gtgtataaca atatggttta   4080

cattttgctc acttttgact tatataaaaa tagaataata ctaaaaaaaa aaaaaaaaa    4139


<210>  799
<211>  844
<212>  DNA
<213>  Human

<400>  799
ccagcggctg cggcggcgga gctcctccga ggtccgggtc accagtctct gctcttccca     60

gcctctccgg cgcgctccaa gggcttcccg tcgggaccat gcgcggccgt gagctcccgc    120

tggtcctgct ggcgctggtc ctctgcctgg cgccccgggg gcgagcggtc ccgctgcctg    180

cgggcggagg gaccgtgctg accaagatgt acccgcgcgg caaccactgg gcggtggggc    240

acttaatggg gaaaaagagc acaggggagt cttcttctgt ttctgagaga gggagcctga    300

agcagcagct gagagagtac atcaggtggg aagaagctgc aaggaatttg ctgggtctca    360

tagaagcaaa ggagaacaga aaccaccagc cacctcaacc caaggccctg ggcaatcagc    420

agccttcgtg ggattcagag gatagcagca acttcaaaga tttggtagac tctctgctcc    480

aggttctcaa cgtgaaggaa ggaaccccca gctgaaccag caatgataat gatggcctct    540

ctcaaaagag aaaaacaaaa cccctaagag actgcgttct gcaagcatca gttctacgga    600

tcatcaacaa gatttccttg tgcaaaatat ttgactattc tgtatctttc atccttgact    660

aaattcgtga ttttcaagca gcatcttctg gtttaaactt gtttgctgtg aacaattgtc    720

gaaaagagtc ttccaattaa tgctttttta tatctaggct acctgttggt tagattcaag    780

gccccgagct gttaccattc acaataaaag cttaaacaca ttgtccaaaa aaaaaaaaaa    840

aaaa                                                                 844


<210>  800
<211>  7169
<212>  DNA
<213>  Human

<400>  800
gggaggagat ccgctcacac acacgaggag gagggttgag ctgccgccgc cgccgcctct     60

gtcgtcgtcg cgagtgtgga gtcgggactg gagctgctgc cgcggcgacg ccggggatct    120

ttgtcgctag ctcccggccc ttctgccccg ccgccttccc tcagtcagcg ttgcccactc    180

ctctccggcc gggcgcccct gcctccattt cccgctctct gtccaccaca cacacggccc    240

ccccgatcat ggatccgggc agtggcggcg gcggcggcgg cggcggcggc ggcgggagca    300

gcagcggcag cagcagcagc gactcggcgc ctgactgctg ggaccaggcg gacatggaag    360

cccccgggcc gggcccttgc ggcggcggcg gctccctggc ggcggcggcc gaggcccagc    420

gggagaacct cagcgcggcc ttcagccggc aactcaacgt caacgccaag cccttcgtgc    480

ccaacgtcca cgccgccgag ttcgtgccgt ccttcctgcg gggcccggca gcgccgccac    540

ccccagctgg cggcgccgcc aataaccacg gagccggcag cggcgcggga ggccgtgcgg    600

cacctgtgga atcctctcaa gaggaacagt cattgtgtga aggttcaaat tcagctgtta    660

gcatggaact ttcagaacct attgtagaaa atggagagac agaaatgtct ccagaagaat    720

catgggagca caaagaagaa ataagtgaag cagagccagg gggtggttcc ttgggagatg    780

gaaggccgcc agaggaaagt gcccatgaaa tgatggagga ggaagaggaa atcccaaaac    840

ctaagtctgt ggttgcaccg ccaggtgctc ctaagaaaga gcatgtaaat gtagtattca    900

ttgggcacgt agatgctggc aagtcaacca ttggaggaca aataatgtat ttgactggaa    960

tggttgacaa aaggacgctt gaaaagtatg aaagagaagc taaagagaaa aacagagaaa   1020

cttggtactt gtcttgggcc ttagacacaa atcaggaaga acgagacaag ggtaaaacag   1080

tagaagtggg tcgtgcctat tttgaaaccg aaaagaagca tttcacaatt ctagatgccc   1140

ctggccacaa gagttttgtc ccaaatatga ttggtggtgc ctctcaagct gatttggctg   1200

tgctggtaat ctcagccagg aaaggagagt ttgaaactgg atttgaaaaa ggaggacaga   1260

caagagaaca tgcaatgttg gcaaagacag caggtgtaaa acacctaatt gtgctaatta   1320

ataagatgga tgatccaaca gtaaattgga gcaatgagag atatgaagaa tgtaaggaga   1380

aactagtgcc atttttgaaa aaagttggct tcaatcccaa aaaggacatt cactttatgc   1440

cctgctcagg acttactgga gcaaatctca aagagcagtc ggatttctgt ccttggtaca   1500

ttggattacc gtttattcca tatctggata atttgccgaa cttcaataga tcagttgatg   1560

gaccaatcag gctgccaatt gtggataagt acaaggatat gggcactgtg gtcctgggaa   1620

agctggaatc aggatctatt tgtaaaggcc agcagcttgt gatgatgcca aacaagcaca   1680

acgtggaagt tcttggaata ctttccgatg atgtagagac tgataccgta gccccaggtg   1740

aaaacctcaa aatcagactg aaaggaattg aagaagagga gattcttcca gggtttatac   1800

tttgtgatcc taataatctt tgtcattctg gacgcacatt tgatgcccag atagtgatta   1860

tagagcacaa atccatcatc tgcccaggct ataatgcggt gctgcatatt catacctgta   1920

ttgaggaggt ggaaataaca gccttaatct gcttggtaga caaaaaatca ggagaaaaaa   1980

gtaagacccg accccgtttt gtcaaacaag atcaagtatg cattgctcgc ttaaggacag   2040

caggaaccat ctgccttgag acctttaaag acttccctca gatgggtcgt ttcaccttaa   2100

gagatgaggg taagaccatt gcaattggaa aagttctgaa actggttcca gagaaagact   2160

aagcattttc ttgatgaccc tgcacaatac tgtgaggaaa attgactgca gaagcctact   2220

tcacaccgcc ttctcttatt ttctgcccat tgataaacct ctccccatat tttgcaaaga   2280

ggaaattcac agcaaaagtc cacattatgt cagctttctc atattgagag ctctgctatg   2340

ccactgttga atttttccca agattcctgt ccctagccct cacttcaaac tctgcttcct   2400

tggacagatt tggcaatagc tttgtaagtg atgtggacat aattgcctac aataatgaaa   2460

acctacagga atttttttat ttttcatttt ccccttaggc atatttagta tttttccccc   2520

aggcagatca ttctgagtgt gcgagtgtgt gtgcacatgt tacaaaggca actaccatgt   2580

taataaaata ttcaatttga aatccttttc ggtatttgaa ttgcttttga ataatgtttt   2640

ttatctggat gtaacattgt tgcattagct ttttaacttt cccaagtaat tgaatacatt   2700

ttattacttg gacttttata aactctttcc ctacccacta taaatgagac attcacagcg   2760

ttcaagtttg tattaaagga aaggattagt ttgacccctt cttttgatgg ttaatgcata   2820

catgcagtta aatcccttta tgcaaatgtg acactgcttt actaggtctt ttagttattt   2880

atttattttt tttttttttg ccaatttata ttgtaacatg atttcttgaa cacagtaagt   2940

tgttttaaaa taaaagaaca gcatactgta gtttttataa gtaaagcgta atgaaattgt   3000

acccctagag aaaattccat taacttgtta aattagtgga attaacaaca aataaagcat   3060

gtttgagacc tggcaaaaat tcctctggta gtatttataa atagagctgc atgcctctag   3120

tatgaaaacc gtatcagttg caagtgccac ttctacaagt tactcagttt actctttgta   3180

tcagtaactt taaaggttgg atgatccttg ctggttaaag ctaaatctca acctagcaac   3240

taaatgaaaa tatttagaat catcagaatc tgaacagact aaaattatca gcgataagca   3300

gaatcaagca gggtataagt tttatctcaa ttatttgaaa ttgactgagt tttcttaagt   3360

gtaaagctga aatttgctaa ccatgttttt gatgaaccac agtgcagcat tgtgtgggtt   3420

ttagattgaa tgactctctg ctataattat catgactttg aaatttttca tgagaataaa   3480

tgaggaatgg aggcaatttg tgggtttatc caaagccccc ttgatgttga gtgttgccat   3540

tgatcaaaga tagcctcttt tagattgtga tttctctcta aataagatac tttgtatatt   3600

taatgacaag tctcttccct ataattttgc tcctcagaaa agaaaagcct agacagactg   3660

tatttccagt cacagaacat aaaacttaat ctaatgggtg ttttgttttg ttttgagaca   3720

gaggctcact ctgtcaccta ggctggagtg cagtggctcg atctcagctc actgcagcct   3780

ccacctcccg gattcaagca atttcctgcc tcagcctctt gagtagctgg gattacagga   3840

gccctccacg aggcccagtt aatttttgta tctttagtgg agacgaggtt tccccctatt   3900

ggtcaggctg gtctcaaact tctgacctca agtgatccac tcgcctcagc ctctcaaaag   3960

tgctgggatt acaggcatga ggcgccgcac ttggcctagt gttttcttaa ctgtgaaatt   4020

cccattcatt tcttgaatga ggctacatct tatggacaga gcaaagttat tgtcctacag   4080

attcttaaaa ctataattat ggctattgca tgaaatttaa atagatttta ttatgtctgc   4140

aaatctctgg gcttttattt ttctggaaaa tataggagct ttaatcaaaa cataatagtt   4200

ctttttgtaa ttccatgtta ataaaaacaa atactagcaa ttgcttgaat tttaatgaat   4260

atttaaaagt tcaagagcca cggaaatcac ttccagagat aagagttccc tttctaaata   4320

gaacacattt ttaaaaaata agttatgttt gctactaaaa catttacact gttagactat   4380

tatgtgcatg ttgccaagac tcttaagtaa cttggatatc aactgtgaag ggcctacctc   4440

taaaaagtaa caggtcatac aaatacaaat gtaactgtaa aaattccact ggattcttgc   4500

atatttgcaa gattagatta ttcaaaagaa atttcagtgc taaaattaac cagcaacata   4560

agttctatgg gctttgaaaa ttgttctcat ctttttaaag ttgatgcatt ttcaatcctg   4620

cttacacagg ctgttcattt ggataagtaa ataaaatgtc taaggtgaac ttggcattat   4680

gtggagatgt tggaccgtta tagagcaata caaattccta tgctgtcatt ctgttttctg   4740

caaatgcaaa cgtgcttata tggtcaacag tgcaaaaata gggtagttgg ctgcatattt   4800

agggtattac ctaagcattt gttctctaac gttgctctac tagaatgatt tttttcttgc   4860

atcttttcac attaatgatg ttctttatat aactttcatg cgattattta gttttttaaa   4920

ttaataaagt gaatttaaga aatattgaaa taaacatcta agtaattgcc attttaaacc   4980

cttgtttctt actgtgggag agggggaaat acagcactca tttcttgttt ttaatttgca   5040

gaagtaagtg aaaatctatg taaaatcaaa ccaaaagagt tggactgagt gtgtattgtc   5100

ttgagattaa gtgacaaata gtaaagtgtt actgagtaat taagcccatg tatttttttt   5160

ttgtgagttg aaaatctttg aaatatgtga taaccgaatg tcaaaagttc ctaaactcta   5220

acagtgcagg ttgttcactg taacgaggta actcatattt gctggttaca taaactacaa   5280

gtactgctct cacaatatgg gactttgaac tgtgatgtag ttcaacagtt gccggcatcc   5340

tctcagctga tacgctgcga atattttggg ttagacttgc agccagatgc agttttgcaa   5400

cccaagaaaa aagttgaacc tatgatcaaa aactgctccc aagatgaacc tggaaaaaaa   5460

tcagctaagc tcccttggcg atctgcagga acactagtaa tgactggaat tactccgtga   5520

tctttgatga ctattacaca taacagcact ctagcacctt ttcttactgg catggacttc   5580

ctcatggact gctacttcat ggatgatagc ttcattgctt tgggtaggga tttaaggtag   5640

tcaaggggaa aatacgcagt tttattacag gtcttaacat caggcaactt tcaactttaa   5700

aaccctttgt gaaaaatgtg gttatagcac tatagctctg attttaggat ggttaaatgt   5760

tatattcatt gttggcttac cttatcaaac tgtgccatta atcctttcac agacataggt   5820

aaggaagaga acaaccagtg gattcagggg acaattatct atctccaaat aataggcttt   5880

tatttcttgc agctaacttt ttcagtgatt ctagcagatg ccatctagta catccttgat   5940

cttgtttctt tcgtgagaga tctcgccatg gcagcatctt gttaagtaag tgtaattgca   6000

catgcacaaa agacttaact agctttacat ttagcagtca gttggttaga ttaggtttca   6060

tagtaaatga ataggaatag aaagaatagg aagtgttttt attttccagt agtaattccg   6120

tggattccat ttgacccagt ttactatcag ttcagttcag gtagatttgg ttcaactttt   6180

ggtggttttt ggctctagga tattcttgac tttaatatcc tagaacttac tgagtcttcc   6240

cttcaataaa tacacttctc acatacctct aatcctatgc ttccttgaaa caataatgct   6300

agctgagttg tttactaagg attattataa gggcctgaag gtgtgggagt ggagattaat   6360

taaaaccttt atgttctcca atataaggga aaagcaggtt ggtactactt ctgattaggc   6420

agaaaacacc aggattcctt aagtgatcct tgaaatggtt attgttttct gccttgtcac   6480

atttgccact gtgcccttta aaacgatgtg gaaacctcag gtttgtggac agcacaggtg   6540

gaatgacatc ttgtgcttcc tgaggctccc ctctaccagg cacattagct tagtgcttca   6600

gatgtcagcc caagtccttg ttacctcctt ttcctgctgc ccagggaaga gtgtgtgtgc   6660

tggagctgga gcgcttgcac tcttcaggtg actattctca cctccatttc ctccacatgc   6720

attaggtgaa actgaggtct aagcctcctg caaggtctac attttaagga ctcacacatc   6780

aggctctcag aaatgtacac aggtattagt tctgtttgtt ctaaaggaaa tgtgggtatc   6840

tctcaggcca ggacttagtg actagttttc gctagacagc aggttaatac ctagatctca   6900

tttaaaaaaa aaaaaaaaaa acaggattaa agggaactga tcaggtttgt tgagtttttt   6960

agcctaattc caaagcatgg aagagtgctc taggtaggaa agaaagcttt ttcttacgat   7020

ttgtagctac ctactgtgcc tgacttggtg cctgtgtgag gattaagccc ttagtctgct   7080

cttgcaatta ttcaaatgac aaattaaatt tgcttttgta ataacaataa aagttgtcat   7140

cttccctttt gaaaaaaaaa aaaaaaaaa                                     7169


<210>  801
<211>  1465
<212>  DNA
<213>  Human

<400>  801
gcctcgcagc cacccctcct gcgtctccac aaatggtccg acccgcaagc aagggggcgg     60

gtccggcttt gaaaagccgg cgggtcgggc cttgaggtgg aaggcgggaa aatggcggat    120

tcctcggggc gaggcgctgg gaagcctgca accggcccca caaattctag cagtgccaag    180

aagaaggata aaagagttca aggtggaaga gtgattgagt cccggtatct gcagtatgaa    240

aagaagacaa cccaaaaggc tcctgcagga gatgggtcac agacccgagg gaagatgtct    300

gaaggtggaa ggaaatccag cctgctccag aaaagcaaag atagcagtgg ggtcggaaag    360

ggtgacctgc agtccacgtt gctggaaggg catggcacag ctccacctga cctggatctc    420

tctgctatta atgacaaaag catcgtcaaa aagacgccac agttagcaaa aacaatatca    480

aagaaacctg agtcaacatc attttctgcc cctcggaaaa agagcccgga tttatctgaa    540

gcaatggaaa tgatggagtc tcagacacta ctgctgacgc tactatccgt aaagatggag    600

aacaatcttg ctgagtttga aagaagggca gaaaagaatt tattaataat gtgtaaggag    660

aaggagaagc tacagaaaaa ggcccacgag ctgaagcgca ggcttctcct ctctcagagg    720

aagcgggagc tggcagatgt cctggatgcc cagatcgaga tgctcagccc cttcgaggca    780

gtggccacac gcttcaagga gcaatacagg acattcgcca cggccctgga cactaccagg    840

cacgagctgc ccgtgaggtc catccacctg gagggagatg ggcagcagct cttagacgcc    900

ctgcagcatg aactggtgac cactcagcgc ctcctgggag aacttgatgt tggtgattcg    960

gaagaaaatg tgcaggtgct ggacttactg agcgaactca aggacgtgac ggcgaaaaag   1020

gaccttgagc tccgaaggag ctttgcccag gtgctggaac tctccgcaga ggcaagcaaa   1080

gaggcagcct tggcaaacca ggaagtctgg gaagagaccc agggcatggc gccccccagc   1140

cggtggtatt tcaatcaaga cagtgcctgc agagaatctg ggggagcacc caagaacacg   1200

cccctgtctg aggacgacaa cccgggtgcc tcgtcagccc ccgctcaggc cacgttcatc   1260

agcccaagcg aagatttttc ttcaagcagc caggcagaag tcccgccctc tctctctcgt   1320

tcagggaggg acttgtcatg actcatggtt acattcagga tacttgagca ctttatatac   1380

taccgtagca ctgtagctat tttttatgtg ataatcttgt ttgataaaaa agtaaacctg   1440

ttttgcaatt gaaaaaaaaa aaaaa                                         1465


<210>  802
<211>  8436
<212>  DNA
<213>  Human

<400>  802
aagatggcgg ctcccacaat tgtggtctga gcgccggcgg ggctgcgacg accgcggcgc     60

ttgtggctcc tttccacccg ccccggaagc cggccagtgc tggggacttg ggggtgtggg    120

aaccgggccg gggctccgcc atttccggcg ggggagggct acgactgagg aagggaggag    180

agagaggcgg ctcaagatgg cggctcccag ggcctcccgc ccgagcttgt aagcgggagc    240

gcccggacaa gtagtcgggg cgacgggact cagcggcctc cagcttcttg agcctaggcg    300

ctcgacagtt tcgggcggct cttgcggaga cggggtgagc gagaagaaag ggaagagcca    360

aagggaagga gggcagttaa gatggcggcc tccatggagt cgtctaccgc tgtgtgagaa    420

accgcttctc cgtgagagct gccttagacg aaagggggtg tgtgaaagga attgaggggc    480

tcccttcccg cttgttgact tctccccacc gcaccctttc ccggaactat ggcttcggcc    540

gtgtcgcccg ccaacttgcc agcggtgctt ctgcagcccc gctggaagcg agtggtgggc    600

tggtcgggtc cggtgccacg gccccgccac ggccaccgcg ccgtggccat caaggagctc    660

atcgtggtgt ttggcggcgg caacgaggga atagtggacg aactgcacgt gtacaacacg    720

gcaaccaacc agtggttcat cccagccgtg aggggggaca ttccccctgg gtgtgcagcc    780

tatggcttcg tgtgtgacgg gactcgcctc ctggtgtttg gtgggatggt ggagtatggg    840

aaatacagca atgacctcta cgaactccag gcgagccggt gggagtggaa gagactcaaa    900

gcaaagacgc ccaaaaacgg gccccctccg tgtcctcgac tcgggcacag cttctccctt    960

gtgggcaaca aatgctacct gtttgggggt ctggccaatg atagcgagga cccaaagaac   1020

aacattccaa ggtacctgaa tgacttatat atcctggaat tacggccagg ctctggagtg   1080

gtagcctggg acattcccat cacttacggg gtcctaccac caccccggga gtcacatact   1140

gccgtggtct acaccgaaaa agacaataag aagtccaagc tggtgatcta cggcgggatg   1200

agtggctgca ggctggggga cctgtggacc ctagatattg acaccctgac gtggaataag   1260

cccagtctca gcggggtggc gcctcttcct cgcagtctcc actcggcaac caccatcgga   1320

aataaaatgt acgtgtttgg tggctgggtg cctctcgtca tggatgacgt caaagtggcc   1380

acacacgaga aggagtggaa gtgtaccaac acgctggctt gtctcaacct ggataccatg   1440

gcctgggaga ccatcctgat ggatacactg gaggacaaca tcccccgtgc tcgggctggc   1500

cactgcgcag tcgccatcaa cacccgcctg tacatttgga gtgggcgtga cggctaccgc   1560

aaggcctgga acaaccaggt ctgctgcaag gacctctggt acctagagac agaaaagcca   1620

ccacccccag cccgagtaca actggtacgc gccaacacca actccctgga ggtgagctgg   1680

ggggcagtgg caacagccga cagctacctt ctccagctcc agaaatatga cattcctgcc   1740

acggctgcta ctgccacctc ccctacaccc aatccggtcc catctgtgcc tgccaaccct   1800

cccaagagcc ctgccccagc agcagccgca cctgctgtgc agccgctgac ccaagtaggc   1860

atcacgctcc tgccccaggc tgcccccgca cccccgacca ccaccaccat ccaggtcttg   1920

ccaacggtgc ctggcagctc catttctgtg cccaccgcag ccaggactca aggtgtccct   1980

gctgttctca aagtgaccgg tcctcaggct acaacaggaa ctccattggt caccatgcga   2040

cctgccagcc aggctgggaa agcccctgtc accgtgacct cccttcccgc cggagtgcgg   2100

atggttgtgc caacacagag tgcccaggga acggtgattg gcagtagccc acagatgagt   2160

gggatggccg cactggccgc tgcggccgct gccacccaga agatcccccc ttcctcggca   2220

cccacggtgc tgagtgtccc agcgggtacc accatcgtga agaccatggc tgtgacacct   2280

ggcactacca ccctcccagc cactgtgaag gtggcctcct cgccagtcat ggtgagcaac   2340

cctgccactc gcatgctgaa gactgcagcc gcccaggtgg ggacatcggt ttcctccgcc   2400

accaacacgt ctacccgccc tatcatcaca gtgcacaagt caggcactgt gacagtggcc   2460

cagcaagccc aggtggtgac cacagttgtg ggcggggtca ccaagaccat caccctggtg   2520

aagagcccca tctctgtccc aggaggcagt gctctgattt ccaatctggg caaagtgatg   2580

tcggtggtcc agaccaaacc agttcagact tcagcagtca caggccaggc gtccacgggt   2640

cctgtgactc agatcatcca gaccaaaggg cccctgccag cgggaacaat cctgaagctg   2700

gtgacctcag cagatggcaa gcccaccacc atcatcacta ccacgcaggc cagtggggcg   2760

gggaccaagc ccaccatcct gggcatcagc agcgtctccc ccagtaccac caagcccggc   2820

acgaccacca tcatcaaaac catccccatg tcggccatca tcacccaggc gggcgccacg   2880

ggtgtgacca gcagtcctgg catcaagtcc cccatcacca tcatcaccac caaggtgatg   2940

acttcaggaa ctggagcacc tgcgaaaatc atcactgctg tccccaaaat tgccactggc   3000

cacgggcagc agggagtgac ccaggtggtg cttaaggggg ccccgggaca gccaggcacc   3060

atcctccgca ctgtgcccat ggggggtgtt cgcctggtca cacccgtcac cgtctccgcc   3120

gtcaagccag ccgtcaccac gttggttgtg aaaggcacca caggtgtcac gaccctaggc   3180

acagtgacag gcaccgtctc caccagcctt gccggggcgg ggggccacag cactagtgct   3240

tccctggcca cgcccatcac caccttgggc accattgcca ccctctcaag ccaggtgatc   3300

aaccccactg ccatcactgt gtcggccgca cagaccacgc tgacagcggc aggcgggctc   3360

acaaccccaa ccatcaccat gcagcccgtg tcccagccca cccaggtaac tctgatcacg   3420

gcacctagtg gggtggaggc ccagcctgtg catgacctcc ctgtgtccat tctggcctcc   3480

ccgactacag aacagcccac cgccacagtt accatcgccg actcaggcca gggtgatgtg   3540

cagcctggca ctgtcacctt ggtgtgctcc aacccaccct gtgagaccca cgagactggc   3600

accaccaaca cggccaccac tactgttgtg gctaaccttg ggggacaccc ccagcccacc   3660

caagtgcagt tcgtctgtga cagacaggag gcagctgctt ctcttgtgac ctcgactgtg   3720

ggccagcaga atggtagcgt ggtccgagtc tgttcgaacc cgccctgcga gacccacgag   3780

acgggcacca ccaacaccgc caccaccgcc acctccaaca tggccgggca gcatggctgc   3840

tcaaacccac cctgcgagac ccacgagacg ggcaccacca acactgccac tacagccatg   3900

tcgagcgtcg gcgccaacca ccagcgagat gcccgtcggg cctgtgcagc tggcacccct   3960

gccgtgatcc ggatcagtgt ggccactggg gcgctggagg cagcccaggg ctctaagtcc   4020

cagtgccaaa cccgccagac cagcgcgacc agcaccacca tgactgtgat ggccaccggg   4080

gccccgtgct cggccggccc actccttggg ccgagcatgg cacgggagcc cgggggccgc   4140

agccctgctt ttgtgcagtt ggcccctctg agcagcaaag tcaggctgag cagcccaagc   4200

attaaggacc ttcctgcggg gcgccacagc catgcggtca gcaccgctgc catgacccgt   4260

tccagcgtgg gtgctgggga gccccgcatg gcacctgtgt gcgagagcct ccagggtggc   4320

tcgcccagca ccacagtgac tgtgacagcc ctggaggcac tgctgtgccc ctcggccacc   4380

gtgacccaag tctgctccaa cccaccatgt gagacccacg agacaggcac caccaacacc   4440

gccactacct cgaatgcagg cagcgcccag agggtgtgct ccaacccgcc atgcgagacc   4500

cacgagacgg gcaccaccca cacggccacc accgctactt caaacggggg cacgggccag   4560

cccgagggtg ggcagcagcc ccctgctggt cgcccctgtg agacacacca gaccacttcc   4620

actggcacca ccatgtcggt cagcgtgggt gccctgcttc ccgacgccac ttcttcccac   4680

aggaccgtgg agtctggcct agaggtggcg gcggcaccca gcgtcacccc ccaggctggc   4740

accgcgctgc tggctccttt cccaacacag agggtgtgct ccaacccccc ctgtgagacc   4800

cacgagacgg gcaccactca cacggccacc actgtcactt ccaacatgag ttcaaaccaa   4860

gaccccccac ctgctgccag cgatcaggga gaggtggaga gcacccaggg cgacagcgtg   4920

aacatcacca gctccagtgc catcacgaca accgtgtcct ccacactgac gcgggctgtg   4980

accaccgtga cgcagtccac accggtcccg ggcccctctg tgccgccccc agaggaactc   5040

caggtgtcgc caggtcctcg ccagcagctg ccgccacggc agcttctgca gtcggcttcc   5100

acagccctga tgggggagtc cgccgaggtc ctgtcagcct cccagacccc tgagctcccg   5160

gccgccgtgg atctgagcag cacaggggag ccatcttcgg gccaggagtc tgccggctct   5220

gcggtggtgg ccactgtggt ggtccagcca cccccaccca cacagtccga agtagaccag   5280

ttatcacttc cccaagagct aatggccgag gcccaagctg gcaccaccac cctcatggta   5340

acggggctca cccccgagga gctggcagtg acggctgctg cagaagcagc tgcccaggcc   5400

gcagccacgg aggaagccca ggccctggcc atccaggcgg tgctccaggc cgcgcagcag   5460

gccgtcatgg gcaccggcga gcccatggac acctccgagg cagcagcaac cgtgactcag   5520

gcggagctgg ggcacctgtc ggccgagggt caggagggcc aggccaccac catacccatt   5580

gtgctgacac agcaggagct ggctgccctg gtgcagcagc agcagctgca ggaggcccag   5640

gcccagcagc agcatcacca cctccccact gaggccctgg cccctgccga cagtctcaac   5700

gacccagcca ttgagagcaa ttgcctcaat gagctggccg gcacggtccc cagcactgtg   5760

gcgctgctgc cctcaacggc cactgagagc ctggctccat ccaacacatt tgtggccccc   5820

cagccggttg tggtggccag cccagccaag ctgcaggctg cagctaccct gaccgaagtg   5880

gccaatggca tcgagtccct gggtgtgaag ccagacctgc cgcccccacc cagcaaagcc   5940

cccatgaaga aggaaaacca gtggtttgat gtgggagtca ttaagggcac caatgtaatg   6000

gtgacacact atttcctgcc accagatgat gctgtcccat cagacgatga tttgggcacc   6060

gtccctgact ataaccagct gaagaagcag gagctgcagc caggcacagc ctataagttt   6120

cgtgttgccg gaatcaatgc ctgtggccgg gggcccttca gcgaaatctc agcctttaag   6180

acgtgcctgc ctggtttccc aggggcccct tgtgccatta aaatcagcaa aagtccggat   6240

ggtgctcacc tcacctggga gccaccctct gtgacctccg gcaagattat cgagtactcc   6300

gtgtacctgg ccatccagag ctcacaggct gggggcgagc tcaagagctc caccccggcc   6360

cagctggcct tcatgcgggt gtactgcggg cccagcccct cctgcctggt gcagtcctcc   6420

agcctttcca acgcccacat cgactacacc accaagcccg ccatcatctt ccgcatcgcc   6480

gcccgcaatg agaagggcta tggcccggcc acacaagtga ggtggctgca ggaaaccagt   6540

aaagacagct ctggcaccaa gccagccaac aagcggccca tgtcctctcc agaaatgaaa   6600

tctgctccaa agaaatctaa ggccgatggt cagtgagagg aagctgacta gcccctggat   6660

tcttctccag acccccctgc ttcaggaaca cccgccaggg cccacccctc ccaccccgtc   6720

ccagcattcg cacttcaccc tcgcgagccg ctgttcactc ctctcccctt tctctttctc   6780

tctgttttta aaataatcta aagaaagcac attttaccat tgctgttggg aggaagcaga   6840

ggcagatggg aaagcagaga gaggagcgcg cttcctttcc tccccgctgc cgcccaccct   6900

ggggagagac ttttgcgggg agggaaggcg gagctgagga cagccagctc cgccctccca   6960

aggctgtgcg ttcctgaggg ccaggtcggg ggcaggcatg gaggggagga aaggcgtccc   7020

tcttggccct ccccagagtg gctttcctgg caccctggcc tgggtgtctg gttctgtttt   7080

cttttcttcc ccttgtgttt ccagtcacct aacttccctt cctcaggctc ccccggccca   7140

ccctgctcag tgaccccaca ggaagcttac acattttctc agaggccttt gtgctcccac   7200

ctcttctacc ctccccctct tctttcccat tttaaaaaag aaaagaagga aaaagaaaaa   7260

aggggcaagg agccccgcgg cggcctgggc agcgcctgtg cagacctccc tgcaggccgc   7320

actgccaact gctgcatttg ttgtgttttt taggttgcaa ttggtgaagt tcacactttc   7380

attgtaattt tagcgtgtgg ggttttgtcc cttttttgtt gttgttagct gtgtacagaa   7440

tgtgtaatct tttttctttt ctcttttttt tgttttgttt tgttttgttt ttgttttttt   7500

acttttttct tcttggctaa ttcttggcag ggatctttct ggaggaaaag ctggggccag   7560

ccagggcagg agaggtgtga aatctgccac gaggggcctg ctgtttgcca cccagcccaa   7620

cttcctgttg ctggcccctg ccctctgccc ttttgcctgt cctcaggccg ctggaacaaa   7680

ggaaggacag ctcattcctc atgggcgatc actccgcatc tatagggtcg agcctagggg   7740

agcttgaggg agggctgggg cctccttgtc ctggatttcc agctctcccc atgccccctc   7800

cctgagcacc accggcaccg cctcccaaac agggctgctg gtttccgcag ccactgctcc   7860

acctccccca aatcgtcatg gaaagggtgg agaatggagg ggaaccaggc gtccttggag   7920

gcagcttggg agggtgactg tgtagtgtca cccacaaggg aggctagggc aatggagcag   7980

gccaccagca gcagctgtgc agcatggaac tcaggccagg ctccgaggct gggggatctg   8040

cttggagttt tctgcccccc accccaaact tctgtcgagg agcaaggctt gccagcaagt   8100

cagaaggatt tgaaccgagc agccaatctt tccagccctc ccctaccgac ctctgcctgg   8160

agacgcagca gcctgtgtcc tccagggcct ctggtttgtt gtattatagt atatttcgct   8220

gtggaaaatg tcacgtttag tcaccttgga gcccactcac ctggtcctgt tgttttaccc   8280

catcccttct ctcgcgcgcc tattgatttg tttctgagga gagtacaccg ttcactattg   8340

tagagtaacc cctgtgactc aatattacca tagtgcgatg tcgttttgtg ctattttgaa   8400

caattaaaag actttttttg aaataaaaaa aaaaaa                             8436


<210>  803
<211>  6427
<212>  DNA
<213>  Human

<400>  803
atagaggctg ggggtggggg gggaggtcaa gcgtagcctc ttctccttta ccaagatggc     60

ggcttgtccc tgtttcgcca cagttcctac cttatgagct cggttttctt atgcttataa    120

gagtggaaca gcaaaagctg gcaggctgac agaggcggcc tcaggacgga ccttctggct    180

actgaccgtt ttgctgtggt tttcccggat tgtgtgtagg tgtgagatca accatgagtt    240

ccgttgcagt tttgacccaa gagagttttg ctgaacaccg aagtgggctg gttccgcaac    300

aaatcaaagt tgccactcta aattcagaag aggagagcga ccctccaacc tacaaggatg    360

ccttccctcc acttcctgag aaagctgctt gcctggaaag tgcccaggaa cccgctggag    420

cctgggggaa caagatccga cccatcaagg cttctgtcat cactcaggtg ttccatgtac    480

ccctggagga gagaaaatac aaggatatga accagtttgg agaaggtgaa caagcaaaaa    540

tctgccttga gatcatgcag agaactggtg ctcacttgga gctgtctttg gccaaagacc    600

aaggcctctc catcatggtg tcaggaaagc tggatgctgt catgaaagct cggaaggaca    660

ttgttgctag actgcagact caggcctcag caactgttgc cattcccaaa gaacaccatc    720

gctttgttat tggcaaaaat ggagagaaac tgcaagactt ggagctaaaa actgcaacca    780

aaatccagat cccacgccca gatgacccca gcaatcagat caagatcact ggcaccaaag    840

agggcatcga gaaagctcgc catgaagtct tactcatctc tgccgagcag gacaaacgtg    900

ctgtggagag gctagaagta gaaaaggcat tccacccctt catcgctggg ccgtataata    960

gactggttgg cgagatcatg caggagacag gcacgcgcat caacatcccc ccacccagcg   1020

tgaaccggac agagattgtc ttcactggag agaaggaaca gttggctcag gctgtggctc   1080

gcatcaagaa gatttatgag gagaagaaaa agaagactac aaccattgca gtggaagtga   1140

agaaatccca acacaagtat gtcattgggc ccaagggcaa ttcattgcag gagatccttg   1200

agagaactgg agtttccgtt gagatcccac cctcagacag catctctgag actgtaatac   1260

ttcgaggcga acctgaaaag ttaggtcagg cgttgactga agtctatgcc aaggccaata   1320

gcttcaccgt ctcctctgtc gccgcccctt cctggcttca ccgtttcatc attggcaaga   1380

aagggcagaa cctggccaaa atcactcagc agatgccaaa ggttcacatc gagttcacag   1440

agggcgaaga caagatcacc ctggagggcc ctacagagga tgtcaatgtg gcccaggaac   1500

agatagaagg catggtcaaa gatttgatta accggatgga ctatgtggag atcaacatcg   1560

accacaagtt ccacaggcac ctcattggga agagcggtgc caacataaac agaatcaaag   1620

accagtacaa ggtgtccgtg cgcatccctc ctgacagtga gaagagcaat ttgatccgca   1680

tcgaggggga cccacagggc gtgcagcagg ccaagcgaga gctgctggag cttgcatctc   1740

gcatggaaaa tgagcgtacc aaggatctaa tcattgagca aagatttcat cgcacaatca   1800

ttgggcagaa gggtgaacgg atccgtgaaa ttcgtgacaa attcccagag gtcatcatta   1860

actttccaga cccagcacaa aaaagtgaca ttgtccagct cagaggacct aagaatgagg   1920

tggaaaaatg cacaaaatac atgcagaaga tggtggcaga tctggtggaa aatagctatt   1980

caatttctgt tccgatcttc aaacagtttc acaagaatat cattgggaaa ggaggcgcaa   2040

acattaaaaa gattcgtgaa gaaagcaaca ccaaaatcga ccttccagca gagaatagca   2100

attcagagac cattatcatc acaggcaagc gagccaactg cgaagctgcc cggagcagga   2160

ttctgtctat tcagaaagac ctggccaaca tagccgaggt agaggtctcc atccctgcca   2220

agctgcacaa ctccctcatt ggcaccaagg gccgtctgat ccgctccatc atggaggagt   2280

gcggcggggt ccacattcac tttcccgtgg aaggttcagg aagcgacacc gttgttatca   2340

ggggcccttc ctcggatgtg gagaaggcca agaagcagct cctgcatctg gcggaggaga   2400

agcaaaccaa gagtttcact gttgacatcc gcgccaagcc agaataccac aaattcctca   2460

tcggcaaggg gggcggcaaa attcgcaagg tgcgcgacag cactggagca cgtgtcatct   2520

tccctgcggc tgaggacaag gaccaggacc tgatcaccat cattggaaag gaggacgccg   2580

tccgagaggc acagaaggag ctggaggcct tgatccaaaa cctggataat gtggtggaag   2640

actccatgct ggtggacccc aagcaccacc gccacttcgt catccgcaga ggccaggtct   2700

tgcgggagat tgctgaagag tatggcgggg tgatggtcag cttcccacgc tctggcacac   2760

agagcgacaa agtcaccctc aagggcgcca aggactgtgt ggaggcagcc aagaaacgca   2820

ttcaggagat cattgaggac ctggaagctc aggtgacatt agaatgtgct ataccccaga   2880

aattccatcg atctgtcatg ggccccaaag gttccagaat ccagcagatt actcgggatt   2940

tcagtgttca aattaaattc ccagacagag aggagaacgc agttcacagt acagagccag   3000

ttgtccagga gaatggggac gaagctgggg aggggagaga ggctaaagat tgtgaccccg   3060

gctctccaag gaggtgtgac atcatcatca tctctggccg gaaagaaaag tgtgaggctg   3120

ccaaggaagc tctggaggca ttggttcctg tcaccattga agtagaggtg ccctttgacc   3180

ttcaccgtta cgttattggg cagaaaggaa gtgggatccg caagatgatg gatgagtttg   3240

aggtgaacat acatgtcccg gcacctgagc tgcagtctga catcatcgcc atcacgggcc   3300

tcgctgcaaa tttggaccgg gccaaggctg gactgctgga gcgtgtgaag gagctacagg   3360

ccgagcagga ggaccgggct ttaaggagtt ttaagctgag tgtcactgta gaccccaaat   3420

accatcccaa gattatcggg agaaaggggg cagtaattac ccaaatccgg ttggagcatg   3480

acgtgaacat ccagtttcct gataaggacg atgggaacca gccccaggac caaattacca   3540

tcacagggta cgaaaagaac acagaagctg ccagggatgc tatactgaga attgtgggtg   3600

aacttgagca gatggtttct gaggacgtcc cgctggacca ccgcgttcac gcccgcatca   3660

ttggtgcccg cggcaaagcc attcgcaaaa tcatggacga attcaaggtg gacattcgct   3720

tcccacagag cggagcccca gaccccaact gcgtcactgt gacggggctc ccagagaatg   3780

tggaggaagc catcgaccac atcctcaatc tggaggagga atacctagct gacgtggtgg   3840

acagtgaggc gctgcaggta tacatgaaac ccccagcaca cgaagaggcc aaggcacctt   3900

ccagaggctt tgtggtgcgg gacgcaccct ggaccgccag cagcagtgag aaggctcctg   3960

acatgagcag ctctgaggaa tttcccagct ttggggctca ggtggctccc aagaccctcc   4020

cttggggccc caaacgataa tgatcaaaaa gaacagaacc ctctccagcc tgctgaccca   4080

aacccaacca cacaatggtt tgtctcaatc tgacccagcg gctggaccct ccgtaaattg   4140

ttgacgctct tcccccttcc cgaggtcccg cagggagcct agcgcctggc tgtgtgtgcg   4200

gccgctcctc caggcctggc cgtgcccgct caggacctgc tccactgttt aacactaaac   4260

caaggtcatg agcattcgtg ctaagataac agactccagc tcctggtcca cccggcatgt   4320

cagtcagcac tctggccttc atcacgagag ctccgcagcc gtggctagga ttccacttcc   4380

tgtgtcatga cctcaggaaa taaacgtcct tgactttata aaagccaaac gtttgccctc   4440

ttcctttccc acctccctcc tgccagtttc ccttggtcca gacagtcctg tttgtggagt   4500

gcaatcagcc tcctccagct gccagagcgc ctcagcacag gtgtcagggt gcaaggaaga   4560

cctggcaatg gacagcagga ggcaggttcc tggagctggg gggtgacctg agaggcagag   4620

ggtgacgggt tctcaggcag tcctgatttt acctgccgtg gggtctgaaa gcaccaaggg   4680

tccctgcccc tacctccact gccagaccct cagcctgagg tctggtgagt ggagcctgga   4740

ggcaaggtgg taggcaccat ctgggtcccc tgtggccgtc acagtgtctg ctgtgattga   4800

gatgcgcaca ggttggggga ggtagggcct tacgcttgtc ctcagtgggg gcagtttgcc   4860

ttagatgaca gctgggctct tcttcacacc acctgcagcc cctccctgcc cctgccctag   4920

ctgctgtgtg ttcagttgcc ttctttctac ctcagccggc gtggagtggt ctctgtgcag   4980

ttagtgccac cccacacacc cgtctcttga ttgagatgtt tctggtggtt atgggtttcc   5040

cgtggagctg ggggtgggcg ccgtgtacct aagctggagg ctggcgctct ccctcagcac   5100

aggtgggtca gtggccagca ggcccatctg gagtgggagt gggcacttcc accccgccca   5160

caggccatcc ggctgtgcag gccagcccct aggagcaggt cccgggtgac tggcagtttt   5220

cacggtctag ggccgagacg atggcatggg gcctagagca tgaggtagag cagaatgcag   5280

accacgccgc tggatgccga gagaccctgc tctccgaggg aggcatctgt gtcatgctgt   5340

gagggctgag gacggggccc tagtctctgg ttttctggtc ttaacatcct tatctgtgtc   5400

cgccacggag gtgactgagc tgctagcgag ttgtcctgtc ccaggtactt gagttttgga   5460

aaagctgact cacgcccatc catctcacag cccttccctg gggacagtcg cttccgcctt   5520

gacacctcac tctcagttga ataactcaag cttggtcatc ttcagactcg aattcttgag   5580

tagacccaga cggcttagcc caagtctagt tgcagctgcc tcggcaagtc cccatttgct   5640

caggcagccc tgaatgggcc tgtttacagg aatggtaaat tgggattgga aggaatatag   5700

cttccagctt cataggctag ggtgaccacg gcttaggaaa cagggaaaga aagcaaggcc   5760

cttttcctgc ctttcccggg atctgtctac tccacctcca cgggggaggc cagtggggaa   5820

gggctgtcac ctcttcccca tctgcatgag ttctggaact ctgtcctgtt ggctgcttgc   5880

ttccagctcc ccccaatctc catcgcagcg ggttcctcct gtcttttcta cagtgtcata   5940

aaacatcctg cccctaccct ctcccaaagg tcaattttaa ttctcaccaa gttttgcaca   6000

tctctgtatg tcgcttgatg tcttagacgc gagccctttc ctaaactgtt cagcgctctc   6060

ttttcctttg ggtggttgtt gcaagggtga tgacatgact gtccccaggc ctgtctccct   6120

gaagcgtctg tgctgtcagg acagccctgg gcagagatga ggcaggggtg aggcgtgcgt   6180

gtgcttttcc tccttgttgg atgtcttcca tatcatctgt ttccatagct acaatccatc   6240

ccttggcctt aactttggaa tttggagatt atatgcaaac atgtgtaaag gctcatgaat   6300

atggatgaca ctggaatttt ataaattcta aaataaaacc cgaaaccaga tgtagcatgc   6360

tgggactcat tttgaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   6420

aaaaaaa                                                             6427


<210>  804
<211>  2257
<212>  DNA
<213>  Human

<400>  804
cttccgtcgg ccattttagg tggtccgcgg cggcgccatt aaagcgagga ggaggcgaga     60

gcggccgccg ctggtgctta ttctttttta gtgcagcggg agagagcggg agtgtgcgcc    120

gcgcgagagt gggaggcgaa gggggcaggc cagggagagg cgcaggagcc tttgcagcca    180

cgcgcgcgcc ttccctgtct tgtgtgcttc gcgaggtaga gcgggcgcgc ggcagcggcg    240

gggattactt tgctgctagt ttcggttcgc ggcagcggcg ggtgtagtct cggcggcagc    300

ggcggagaca ctagcactat gtcggaggag cagttcggcg gggacggggc ggcggcagcg    360

gcaacggcgg cggtaggcgg ctcggcgggc gagcaggagg gagccatggt ggcggcgaca    420

cagggggcag cggcggcggc gggaagcgga gccgggaccg ggggcggaac cgcgtctgga    480

ggcaccgaag ggggcagcgc cgagtcggag ggggcgaaga ttgacgccag taagaacgag    540

gaggatgaag gccattcaaa ctcctcccca cgacactctg aagcagcgac ggcacagcgg    600

gaagaatgga aaatgtttat aggaggcctt agctgggaca ctacaaagaa agatctgaag    660

gactactttt ccaaatttgg tgaagttgta gactgcactc tgaagttaga tcctatcaca    720

gggcgatcaa ggggttttgg ctttgtgcta tttaaagaat cggagagtgt agataaggtc    780

atggatcaaa aagaacataa attgaatggg aaggtgattg atcctaaaag ggccaaagcc    840

atgaaaacaa aagagccggt taaaaaaatt tttgttggtg gcctttctcc agatacacct    900

gaagagaaaa taagggagta ctttggtggt tttggtgagg tggaatccat agagctcccc    960

atggacaaca agaccaataa gaggcgtggg ttctgcttta ttacctttaa ggaagaagaa   1020

ccagtgaaga agataatgga aaagaaatac cacaatgttg gtcttagtaa atgtgaaata   1080

aaagtagcca tgtcgaagga acaatatcag caacagcaac agtggggatc tagaggagga   1140

tttgcaggaa gagctcgtgg aagaggtggt ggccccagtc aaaactggaa ccagggatat   1200

agtaactatt ggaatcaagg ctatggcaac tatggatata acagccaagg ttacggtggt   1260

tatggaggat atgactacac tggttacaac aactactatg gatatggtga ttatagcaac   1320

cagcagagtg gttatgggaa ggtatccagg cgaggtggtc atcaaaatag ctacaaacca   1380

tactaaatta ttccatttgc aacttatccc caacaggtgg tgaagcagta ttttccaatt   1440

tgaagattca tttgaaggtg gctcctgcca cctgctaata gcagttcaaa ctaaattttt   1500

tgtatcaagt ccctgaatgg aagtatgacg ttgggtccct ctgaagttta attctgagtt   1560

ctcattaaaa gaaatttgct ttcattgttt tatttcttaa ttgctatgct tcagaatcaa   1620

tttgtgtttt atgccctttc ccccagtatt gtagagcaag tcttgtgtta aaagcccagt   1680

gtgacagtgt catgatgtag tagtgtctta ctggtttttt aataaatcct tttgtataaa   1740

aatgtattgg ctcttttatc atcagaatag gaaaaattgt catggattca agttattaaa   1800

agcataagtt tggaagacag gcttgccgaa attgaggaca tgattaaaat tgcagtgaag   1860

tttgaaatgt ttttagcaaa atctaatttt tgccataatg tgtcctccct gtccaaattg   1920

ggaatgactt aatgtcaatt tgtttgttgg ttgttttaat aatacttcct tatgtagcca   1980

ttaagattta tatgaatatt ttcccaaatg cccagttttt gcttaatatg tattgtgctt   2040

tttagaacaa atctggataa atgtgcaaaa gtaccccttt gcacagatag ttaatgtttt   2100

atgcttccat taaataaaaa ggacttaaaa tctgttaatt ataatagaaa tgcggctagt   2160

tcagagagat ttttagagct gtggtggact tcatagatga attcaagtgt tgagggagga   2220

ttaaagaaat atataccgtg tttatgtgtg tgtgctt                            2257


<210>  805
<211>  3366
<212>  DNA
<213>  Human

<400>  805
gcatgcgtag gcgcgcggcc gcggcggcgg ctggggaggg ttcttccgga aggttcggga     60

ggcttctgga aaaagcgccg cgcgctgggc gggcccgtcg ctatataagg caggcgcggg    120

ggtggcgcgt cagttgcttc agcgtcccgg tgtggctgtg ccgttggtcc tgtgcggtca    180

cttagccaag atgcctgagg aaacccagac ccaagaccaa ccgatggagg aggaggaggt    240

tgagacgttc gcctttcagg cagaaattgc ccagttgatg tcattgatca tcaatacttt    300

ctactcgaac aaagagatct ttctgagaga gctcatttca aattcatcag atgcattgga    360

caaaatccgg tatgaaagct tgacagatcc cagtaaatta gactctggga aagagctgca    420

tattaacctt ataccgaaca aacaagatcg aactctcact attgtggata ctggaattgg    480

aatgaccaag gctgacttga tcaataacct tggtactatc gccaagtctg ggaccaaagc    540

gttcatggaa gctttgcagg ctggtgcaga tatctctatg attggccagt tcggtgttgg    600

tttttattct gcttatttgg ttgctgagaa agtaactgtg atcaccaaac ataacgatga    660

tgagcagtac gcttgggagt cctcagcagg gggatcattc acagtgagga cagacacagg    720

tgaacctatg ggtcgtggaa caaaagttat cctacacctg aaagaagacc aaactgagta    780

cttggaggaa cgaagaataa aggagattgt gaagaaacat tctcagttta ttggatatcc    840

cattactctt tttgtggaga aggaacgtga taaagaagta agcgatgatg aggctgaaga    900

aaaggaagac aaagaagaag aaaaagaaaa agaagagaaa gagtcggaag acaaacctga    960

aattgaagat gttggttctg atgaggaaga agaaaagaag gatggtgaca agaagaagaa   1020

gaagaagatt aaggaaaagt acatcgatca agaagagctc aacaaaacaa agcccatctg   1080

gaccagaaat cccgacgata ttactaatga ggagtacgga gaattctata agagcttgac   1140

caatgactgg gaagatcact tggcagtgaa gcatttttca gttgaaggac agttggaatt   1200

cagagccctt ctatttgtcc cacgacgtgc tccttttgat ctgtttgaaa acagaaagaa   1260

aaagaacaac atcaaattgt atgtacgcag agttttcatc atggataact gtgaggagct   1320

aatccctgaa tatctgaact tcattagagg ggtggtagac tcggaggatc tccctctaaa   1380

catatcccgt gagatgttgc aacaaagcaa aattttgaaa gttatcagga agaatttggt   1440

caaaaaatgc ttagaactct ttactgaact ggcggaagat aaagagaact acaagaaatt   1500

ctatgagcag ttctctaaaa acataaagct tggaatacac gaagactctc aaaatcggaa   1560

gaagctttca gagctgttaa ggtactacac atctgcctct ggtgatgaga tggtttctct   1620

caaggactac tgcaccagaa tgaaggagaa ccagaaacat atctattata tcacaggtga   1680

gaccaaggac caggtagcta actcagcctt tgtggaacgt cttcggaaac atggcttaga   1740

agtgatctat atgattgagc ccattgatga gtactgtgtc caacagctga aggaatttga   1800

ggggaagact ttagtgtcag tcaccaaaga aggcctggaa cttccagagg atgaagaaga   1860

gaaaaagaag caggaagaga aaaaaacaaa gtttgagaac ctctgcaaaa tcatgaaaga   1920

catattggag aaaaaagttg aaaaggtggt tgtgtcaaac cgattggtga catctccatg   1980

ctgtattgtc acaagcacat atggctggac agcaaacatg gagagaatca tgaaagctca   2040

agccctaaga gacaactcaa caatgggtta catggcagca aagaaacacc tggagataaa   2100

ccctgaccat tccattattg agaccttaag gcaaaaggca gaggctgata agaacgacaa   2160

gtctgtgaag gatctggtca tcttgcttta tgaaactgcg ctcctgtctt ctggcttcag   2220

tctggaagat ccccagacac atgctaacag gatctacagg atgatcaaac ttggtctggg   2280

tattgatgaa gatgacccta ctgctgatga taccagtgct gctgtaactg aagaaatgcc   2340

accccttgaa ggagatgacg acacatcacg catggaagaa gtagactaat ctctggctga   2400

gggatgactt acctgttcag tactctacaa ttcctctgat aatatatttt caaggatgtt   2460

tttctttatt tttgttaata ttaaaaagtc tgtatggcat gacaactact ttaaggggaa   2520

gataagattt ctgtctacta agtgatgctg tgatacctta ggcactaaag cagagctagt   2580

aatgcttttt gagtttcatg ttggtttatt ttcacagatt ggggtaacgt gcactgtaag   2640

acgtatgtaa catgatgtta actttgtggt ctaaagtgtt tagctgtcaa gccggatgcc   2700

taagtagacc aaatcttgtt attgaagtgt tctgagctgt atcttgatgt ttagaaaagt   2760

attcgttaca tcttgtagga tctacttttt gaacttttca ttccctgtag ttgacaattc   2820

tgcatgtact agtcctctag aaataggtta aactgaagca acttgatgga aggatctctc   2880

cacagggctt gttttccaaa gaaaagtatt gtttggagga gcaaagttaa aagcctacct   2940

aagcatatcg taaagctgtt caaaaataac tcagacccag tcttgtggat ggaaatgtag   3000

tgctcgagtc acattctgct taaagttgta acaaatacag atgagttaaa agatattgtg   3060

tgacagtgtc ttatttaggg ggaaagggga gtatctggat gacagttagt gccaaaatgt   3120

aaaacatgag gcgctagcag gagatggtta aacactagct gctccaaggg ttgacatggt   3180

cttcccagca tgtactcagc aggtgtgggg tggagcacac gtaggcacag aaaacaggaa   3240

tgcagacaac atgcatcccc tgcgtccatg agttacatgt gttctcttag tgtccacgtt   3300

gttttgatgt tattcatgga ataccttctg tgttaaatac agtcacttaa ttccttggcc   3360

ttaaaa                                                              3366


<210>  806
<211>  2879
<212>  DNA
<213>  Human

<400>  806
gattggtggg ttcatgtttc ccgtcccccg cccgcgggaa gtgggggtga aaagcggccc     60

gacctgcttg cggtgtagtg ggcggaccgc gcggctggag gtgtgaggat ccgaacccag    120

gggtgggggg tggaggcggc tcctgcgatc gaaggggact tgagactcac cggccgcacg    180

ccatgagggc cctgtgggtg ctgggcctct gctgcgtcct gctgaccttc gggtcggtca    240

gagctgacga tgaagttgat gtggatggta cagtagaaga ggatctgggt aaaagtagag    300

aaggatcaag gacggatgat gaagtagtac agagagagga agaagctatt cagttggatg    360

gattaaatgc atcacaaata agagaactta gagagaagtc ggaaaagttt gccttccaag    420

ccgaagttaa cagaatgatg aaacttatca tcaattcatt gtataaaaat aaagagattt    480

tcctgagaga actgatttca aatgcttctg atgctttaga taagataagg ctaatatcac    540

tgactgatga aaatgctctt tctggaaatg aggaactaac agtcaaaatt aagtgtgata    600

aggagaagaa cctgctgcat gtcacagaca ccggtgtagg aatgaccaga gaagagttgg    660

ttaaaaacct tggtaccata gccaaatctg ggacaagcga gtttttaaac aaaatgactg    720

aagcacagga agatggccag tcaacttctg aattgattgg ccagtttggt gtcggtttct    780

attccgcctt ccttgtagca gataaggtta ttgtcacttc aaaacacaac aacgataccc    840

agcacatctg ggagtctgac tccaatgaat tttctgtaat tgctgaccca agaggaaaca    900

ctctaggacg gggaacgaca attacccttg tcttaaaaga agaagcatct gattaccttg    960

aattggatac aattaaaaat ctcgtcaaaa aatattcaca gttcataaac tttcctattt   1020

atgtatggag cagcaagact gaaactgttg aggagcccat ggaggaagaa gaagcagcca   1080

aagaagagaa agaagaatct gatgatgaag ctgcagtaga ggaagaagaa gaagaaaaga   1140

aaccaaagac taaaaaagtt gaaaaaactg tctgggactg ggaacttatg aatgatatca   1200

aaccaatatg gcagagacca tcaaaagaag tagaagaaga tgaatacaaa gctttctaca   1260

aatcattttc aaaggaaagt gatgacccca tggcttatat tcactttact gctgaagggg   1320

aagttacctt caaatcaatt ttatttgtac ccacatctgc tccacgtggt ctgtttgacg   1380

aatatggatc taaaaagagc gattacatta agctctatgt gcgccgtgta ttcatcacag   1440

acgacttcca tgatatgatg cctaaatacc tcaattttgt caagggtgtg gtggactcag   1500

atgatctccc cttgaatgtt tcccgcgaga ctcttcagca acataaactg cttaaggtga   1560

ttaggaagaa gcttgttcgt aaaacgctgg acatgatcaa gaagattgct gatgataaat   1620

acaatgatac tttttggaaa gaatttggta ccaacatcaa gcttggtgtg attgaagacc   1680

actcgaatcg aacacgtctt gctaaacttc ttaggttcca gtcttctcat catccaactg   1740

acattactag cctagaccag tatgtggaaa gaatgaagga aaaacaagac aaaatctact   1800

tcatggctgg gtccagcaga aaagaggctg aatcttctcc atttgttgag cgacttctga   1860

aaaagggcta tgaagttatt tacctcacag aacctgtgga tgaatactgt attcaggccc   1920

ttcccgaatt tgatgggaag aggttccaga atgttgccaa ggaaggagtg aagttcgatg   1980

aaagtgagaa aactaaggag agtcgtgaag cagttgagaa agaatttgag cctctgctga   2040

attggatgaa agataaagcc cttaaggaca agattgaaaa ggctgtggtg tctcagcgcc   2100

tgacagaatc tccgtgtgct ttggtggcca gccagtacgg atggtctggc aacatggaga   2160

gaatcatgaa agcacaagcg taccaaacgg gcaaggacat ctctacaaat tactatgcga   2220

gtcagaagaa aacatttgaa attaatccca gacacccgct gatcagagac atgcttcgac   2280

gaattaagga agatgaagat gataaaacag ttttggatct tgctgtggtt ttgtttgaaa   2340

cagcaacgct tcggtcaggg tatcttttac cagacactaa agcatatgga gatagaatag   2400

aaagaatgct tcgcctcagt ttgaacattg accctgatgc aaaggtggaa gaagagcccg   2460

aagaagaacc tgaagagaca gcagaagaca caacagaaga cacagagcaa gacgaagatg   2520

aagaaatgga tgtgggaaca gatgaagaag aagaaacagc aaaggaatct acagctgaaa   2580

aagatgaatt gtaaattata ctctcaccat ttggatcctg tgtggagagg gaatgtgaaa   2640

tttacatcat ttctttttgg gagagacttg ttttggatgc cccctaatcc ccttctcccc   2700

tgcactgtaa aatgtgggat tatgggtcac aggaaaaagt gggtttttta gttgaatttt   2760

ttttaacatt cctcatgaat gtaaatttgt actatttaac tgactattct tgatgtaaaa   2820

tcttgtcatg tgtataaaaa taaaaaagat cccaaatact caaaaaaaaa aaaaaaaaa    2879


<210>  807
<211>  2551
<212>  DNA
<213>  Human

<400>  807
ggaaaacggc cagcctgagg agctgctgcg agggtccgct tcgtctttcg agagtgactc     60

ccgcggtccc aaggctttcc agagcgaacc tgtgcggctg caggcaccgg cgtgttgagt    120

ttccggcgtt ccgaaggact gagctcttgt cgcggatccc gtccgccgtt tccagccccc    180

agtctcagag cggagcccac agagcagggc accggcatgg ccaaagccgc ggcgatcggc    240

atcgacctgg gcaccaccta ctcctgcgtg ggggtgttcc aacacggcaa ggtggagatc    300

atcgccaacg accagggcaa ccgcaccacc cccagctacg tggccttcac ggacaccgag    360

cggctcatcg gggatgcggc caagaaccag gtggcgctga acccgcagaa caccgtgttt    420

gacgcgaagc ggctgatcgg ccgcaagttc ggcgacccgg tggtgcagtc ggacatgaag    480

cactggcctt tccaggtgat caacgacgga gacaagccca aggtgcaggt gagctacaag    540

ggggagacca aggcattcta ccccgaggag atctcgtcca tggtgctgac caagatgaag    600

gagatcgccg aggcgtacct gggctacccg gtgaccaacg cggtgatcac cgtgccggcc    660

tacttcaacg actcgcagcg ccaggccacc aaggatgcgg gtgtgatcgc ggggctcaac    720

gtgctgcgga tcatcaacga gcccacggcc gccgccatcg cctacggcct ggacagaacg    780

ggcaaggggg agcgcaacgt gctcatcttt gacctgggcg ggggcacctt cgacgtgtcc    840

atcctgacga tcgacgacgg catcttcgag gtgaaggcca cggccgggga cacccacctg    900

ggtggggagg actttgacaa caggctggtg aaccacttcg tggaggagtt caagagaaaa    960

cacaagaagg acatcagcca gaacaagcga gccgtgaggc ggctgcgcac cgcctgcgag   1020

agggccaaga ggaccctgtc gtccagcacc caggccagcc tggagatcga ctccctgttt   1080

gagggcatcg acttctacac gtccatcacc agggcgaggt tcgaggagct gtgctccgac   1140

ctgttccgaa gcaccctgga gcccgtggag aaggctctgc gcgacgccaa gctggacaag   1200

gcccagattc acgacctggt cctggtcggg ggctccaccc gcatccccaa ggtgcagaag   1260

ctgctgcagg acttcttcaa cgggcgcgac ctgaacaaga gcatcaaccc cgacgaggct   1320

gtggcctacg gggcggcggt gcaggcggcc atcctgatgg gggacaagtc cgagaacgtg   1380

caggacctgc tgctgctgga cgtggctccc ctgtcgctgg ggctggagac ggccggaggc   1440

gtgatgactg ccctgatcaa gcgcaactcc accatcccca ccaagcagac gcagatcttc   1500

accacctact ccgacaacca acccggggtg ctgatccagg tgtacgaggg cgagagggcc   1560

atgacgaaag acaacaatct gttggggcgc ttcgagctga gcggcatccc tccggccccc   1620

aggggcgtgc cccagatcga ggtgaccttc gacatcgatg ccaacggcat cctgaacgtc   1680

acggccacgg acaagagcac cggcaaggcc aacaagatca ccatcaccaa cgacaagggc   1740

cgcctgagca aggaggagat cgagcgcatg gtgcaggagg cggagaagta caaagcggag   1800

gacgaggtgc agcgcgagag ggtgtcagcc aagaacgccc tggagtccta cgccttcaac   1860

atgaagagcg ccgtggagga tgaggggctc aagggcaaga tcagcgaggc ggacaagaag   1920

aaggttctgg acaagtgtca agaggtcatc tcgtggctgg acgccaacac cttggccgag   1980

aaggacgagt ttgagcacaa gaggaaggag ctggagcagg tgtgtaaccc catcatcagc   2040

ggactgtacc agggtgccgg tggtcccggg cctggcggct tcggggctca gggtcccaag   2100

ggagggtctg ggtcaggccc taccattgag gaggtggatt aggggccttt gttctttagt   2160

atgtttgtct ttgaggtgga ctgttgggac tcaaggactt tgctgctgtt ttcctatgtc   2220

atttctgctt cagctctttg ctgcttcact tctttgtaaa gttgtaacct gatggtaatt   2280

agctggcttc attatttttg tagtacaacc gatatgttca ttagaattct ttgcatttaa   2340

tgttgatact gtaagggtgt ttcgttccct ttaaatgaat caacactgcc accttctgta   2400

cgagtttgtt tgtttttttt tttttttttt ttttttgctt ggcgaaaaca ctacaaaggc   2460

tgggaatgta tgtttttata atttgtttat ttaaatatga aaaataaaat gttaaacttt   2520

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a                                  2551


<210>  808
<211>  914
<212>  DNA
<213>  Human

<400>  808
gcatggggag gggcggccct caaacgggtc attgccatta atagagacct caaacaccgc     60

ctgctaaaaa tacccgactg gaggagcata aaagcgcagc cgagcccagc gccccgcact    120

tttctgagca gacgtccaga gcagagtcag ccagcatgac cgagcgccgc gtccccttct    180

cgctcctgcg gggccccagc tgggacccct tccgcgactg gtacccgcat agccgcctct    240

tcgaccaggc cttcgggctg ccccggctgc cggaggagtg gtcgcagtgg ttaggcggca    300

gcagctggcc aggctacgtg cgccccctgc cccccgccgc catcgagagc cccgcagtgg    360

ccgcgcccgc ctacagccgc gcgctcagcc ggcaactcag cagcggggtc tcggagatcc    420

ggcacactgc ggaccgctgg cgcgtgtccc tggatgtcaa ccacttcgcc ccggacgagc    480

tgacggtcaa gaccaaggat ggcgtggtgg agatcaccgg caagcacgag gagcggcagg    540

acgagcatgg ctacatctcc cggtgcttca cgcggaaata cacgctgccc cccggtgtgg    600

accccaccca agtttcctcc tccctgtccc ctgagggcac actgaccgtg gaggccccca    660

tgcccaagct agccacgcag tccaacgaga tcaccatccc agtcaccttc gagtcgcggg    720

cccagcttgg gggcccagaa gctgcaaaat ccgatgagac tgccgccaag taaagcctta    780

gcccggatgc ccacccctgc tgccgccact ggctgtgcct cccccgccac ctgtgtgttc    840

ttttgataca tttatcttct gtttttctca aataaagttc aaagcaacca cctgtcaaaa    900

aaaaaaaaaa aaaa                                                      914


<210>  809
<211>  2138
<212>  DNA
<213>  Human

<400>  809
caatgggctg ggccgcgcgg ccgcgcgcac tcgcacccgc tgcccccgag gccctcctgc     60

actctccccg gcgccgctct ccggccctcg ccctgtccgc cgccaccgcc gccgccgcca    120

gagtcgccat gcagatcccg cgcgccgctc ttctcccgct gctgctgctg ctgctggcgg    180

cgcccgcctc ggcgcagctg tcccgggccg gccgctcggc gcctttggcc gccgggtgcc    240

cagaccgctg cgagccggcg cgctgcccgc cgcagccgga gcactgcgag ggcggccggg    300

cccgggacgc gtgcggctgc tgcgaggtgt gcggcgcgcc cgagggcgcc gcgtgcggcc    360

tgcaggaggg cccgtgcggc gaggggctgc agtgcgtggt gcccttcggg gtgccagcct    420

cggccacggt gcggcggcgc gcgcaggccg gcctctgtgt gtgcgccagc agcgagccgg    480

tgtgcggcag cgacgccaac acctacgcca acctgtgcca gctgcgcgcc gccagccgcc    540

gctccgagag gctgcaccgg ccgccggtca tcgtcctgca gcgcggagcc tgcggccaag    600

ggcaggaaga tcccaacagt ttgcgccata aatataactt tatcgcggac gtggtggaga    660

agatcgcccc tgccgtggtt catatcgaat tgtttcgcaa gcttccgttt tctaaacgag    720

aggtgccggt ggctagtggg tctgggttta ttgtgtcgga agatggactg atcgtgacaa    780

atgcccacgt ggtgaccaac aagcaccggg tcaaagttga gctgaagaac ggtgccactt    840

acgaagccaa aatcaaggat gtggatgaga aagcagacat cgcactcatc aaaattgacc    900

accagggcaa gctgcctgtc ctgctgcttg gccgctcctc agagctgcgg ccgggagagt    960

tcgtggtcgc catcggaagc ccgttttccc ttcaaaacac agtcaccacc gggatcgtga   1020

gcaccaccca gcgaggcggc aaagagctgg ggctccgcaa ctcagacatg gactacatcc   1080

agaccgacgc catcatcaac tatggaaact cgggaggccc gttagtaaac ctggacggtg   1140

aagtgattgg aattaacact ttgaaagtga cagctggaat ctcctttgca atcccatctg   1200

ataagattaa aaagttcctc acggagtccc atgaccgaca ggccaaagga aaagccatca   1260

ccaagaagaa gtatattggt atccgaatga tgtcactcac gtccagcaaa gccaaagagc   1320

tgaaggaccg gcaccgggac ttcccagacg tgatctcagg agcgtatata attgaagtaa   1380

ttcctgatac cccagcagaa gctggtggtc tcaaggaaaa cgacgtcata atcagcatca   1440

atggacagtc cgtggtctcc gccaatgatg tcagcgacgt cattaaaagg gaaagcaccc   1500

tgaacatggt ggtccgcagg ggtaatgaag atatcatgat cacagtgatt cccgaagaaa   1560

ttgacccata ggcagaggca tgagctggac ttcatgtttc cctcaaagac tctcccgtgg   1620

atgacggatg aggactctgg gctgctggaa taggacactc aagacttttg actgccattt   1680

tgtttgttca gtggagactc cctggccaac agaatccttc ttgatagttt gcaggcaaaa   1740

caaatgtaat gttgcagatc cgcaggcaga agctctgccc ttctgtatcc tatgtatgca   1800

gtgtgctttt tcttgccagc ttgggccatt cttgcttaga cagtcagcat ttgtctcctc   1860

ctttaactga gtcatcatct tagtccaact aatgcagtcg atacaatgcg tagatagaag   1920

aagccccacg ggagccagga tgggactggt cgtgtttgtg cttttctcca agtcagcacc   1980

caaaggtcaa tgcacagaga ccccgggtgg gtgagcgctg gcttctcaaa cggccgaagt   2040

tgcctctttt aggaatctct ttggaattgg gagcacgatg actctgagtt tgagctatta   2100

aagtacttct tacacattgc aaaaaaaaaa aaaaaaaa                           2138


<210>  810
<211>  2268
<212>  DNA
<213>  Human

<400>  810
gctgcaggaa gcagcaggag acgcccggca gccgggacgg tcggggacgc ctgaagaaga     60

agaaaacatg tcaggacaca aatgcagtta tccctgggac ttacaggatc gatatgctca    120

agataagtca gttgtaaata agatgcaaca gaaatattgg gagacgaagc aggcctttat    180

taaagccaca gggaagaagg aagatgaaca tgttgttgcc tctgacgcgg acctggatgc    240

caagctagag ctgtttcatt caattcagag aacctgtctg gacttatcga aagcaattgt    300

actctatcaa aagaggatat gtttcttgtc tcaagaagaa aacgaactgg gaaaatttct    360

tcgatcccaa ggtttccaag ataaaaccag agcaggaaag atgatgcaag cgacaggaaa    420

ggccctctgc ttttcttccc agcaaaggtt ggccttacga aatcctttgt gtcgatttca    480

ccaagaagtg gagacttttc ggcatcgggc catctcagat acttggctga cggtgaaccg    540

catggaacag tgcaggacgg aatatagagg agcactatta tggatgaagg acgtgtctca    600

ggagcttgat ccagacctct acaagcaaat ggagaagttc aggaaggtac aaacacaagt    660

gcgccttgca aaaaaaaact ttgacaaatt gaagatggat gtttgtcaaa aagtggatct    720

tcttggagcg agcagatgca atctcttgtc tcacatgcta gcaacatacc agaccactct    780

gcttcatttt tgggagaaaa cttctcacac tatggcagcc atccatgaga gtttcaaagg    840

ttatcaacca tatgaattta ctactttaaa gagcttacaa gaccctatga aaaaattagt    900

tgagaaagaa gagaagaaga aaatcaacca gcaggaaagt acagatgcag ccgtgcagga    960

gccgagccaa ttaatttcat tagaggaaga aaaccagcgc aaggaatcct ctagttttaa   1020

gactgaagat ggaaaaagta ttttatctgc cttagacaaa ggctctacac atactgcatg   1080

ctcaggaccc atagatgaac tattagacat gaaatctgag gaaggtgctt gcctgggacc   1140

agtggcaggg accccggaac ctgaaggtgc tgacaaagat gacctgctgc tgttgagtga   1200

gatcttcaat gcttcctcct tggaagaggg cgagttcagc aaagagtggg ccgctgtgtt   1260

tggagacggc caagtgaagg agccagtgcc cactatggcc ctgggagagc cagaccccaa   1320

ggcccagaca ggctcaggtt tccttccttc gcagctttta gaccaaaata tgaaagactt   1380

acaggcctcg ctacaagaac ctgctaaggc tgcctcagac ctgactgcct ggttcagcct   1440

cttcgctgac ctcgacccac tctcaaatcc tgatgctgtt gggaaaaccg ataaagaaca   1500

cgaattgctc aatgcatgaa tctgtaccct tcgggagggc actcacatgc cgcccccagc   1560

agctcccctg ggggctagca gaagtataaa gtgatcagta tgctgtttta ataattatgt   1620

gccattttaa taaaatgaaa gggtcaacgg ccctgtttat attggtataa ttatttactc   1680

ttatttggta taaagggttt tcgtgtatct ctatgtggat ctaaataata caggattgtc   1740

tagaagcggt ttccaggcca ccgctctcct gcctacatcc catcatggct gctgcggtgt   1800

cactgggcta ccgtgagatc caagttgaaa tcagaagcct actttgatgg taggtttgaa   1860

tgacgtgtcc tacagcctca gaggcagcag gaggctagca aagcttaaat gcctccttct   1920

ctgcccccag cctctgtccc ccttggagga gggctgtagg aagattccct cttcctgcca   1980

agccaccttc cagtgagctc tggatgaagc tctggccaac caaagacact gtccccacag   2040

caggtgcctg gtgggccacg tgttctcaca ctggtggagg agctgggctt ctgtccaagg   2100

cacaaacctt actatggaaa gcagccatat ttgcagatac cactgtctcc ttttgtcctc   2160

ttcgtggctg gaattcaaaa gcatgtattt ctgaagcctc ttgtgacatt gttttttttt   2220

tttttttaat taaacagaaa agatatttga catgcaaaaa aaaaaaaa                2268


<210>  811
<211>  1955
<212>  DNA
<213>  Human

<400>  811
acgcaaagca gtgtgggttg attctgaggt gcactgtggg aaagagcttg tcgctgcggt     60

gttgctgttg gagactcgat tgttggtgac agcgaaagaa cgataacaaa atgccggagc    120

gagatagtga gccgttctcc aaccctttgg cccccgatgg ccacgatgtg gatgatcctc    180

actccttcca ccaatcaaaa ctcaccaatg aagacttcag gaaacttctc atgaccccca    240

gggctgcacc tacctctgca ccaccttcta agtcacgtca ccatgagatg ccaagggagt    300

acaatgagga tgaagaccca gctgcacgaa ggaggaaaaa gaaaagttat tatgccaagc    360

tacgccaaca agaaattgag agagagagag agctagcaga gaagtaccgg gatcgtgcca    420

aggaacggag agatggagtg aacaaagatt atgaagaaac cgagcttatc agcaccacag    480

ctaactatag ggctgttggc cccactgctg aggcggacaa atcagctgca gagaagagaa    540

gacagttgat ccaggagtcc aaattcttgg gtggtgacat ggaacacacc catttggtga    600

aaggcttgga ttttgctctg cttcaaaagg tacgagctga gattgccagc aaagagaaag    660

aggaagagga actgatggaa aagccccaga aagaaaccaa gaaagatgag gatcctgaaa    720

ataaaattga atttaaaaca cgtctgggcc gcaatgttta ccgaatgctt tttaagagca    780

aagcatatga gcggaatgag ttgttcctgc cgggccgcat ggcctatgtg gtagacctgg    840

atgatgagta tgctgacaca gatatcccca ccactcttat ccgcagcaag gctgattgcc    900

ccaccatgga ggcccagacc acactgacca caaatgacat tgtcattagc aagctgaccc    960

agatcctttc atacctgagg cagggaaccc gtaacaagaa gcttaagaag aaggataaag   1020

ggaagctgga agagaagaaa cctcctgagg ctgacatgaa tatttttgaa gacattgggg   1080

attacgtacc ctccacaacc aagacacctc gggacaagga gcgggagaga tatcgggaac   1140

gggagcgtga tcgggaaaga gacagagacc gtgaccgaga gcgagagcga gaacgagatc   1200

gggaacgaga gcgagagcgg gaccgagaga gagaagagga aaagaagaga cacagctact   1260

ttgagaagcc aaaagtagat gatgagccca tggacgttga caaaggacct gggtctacca   1320

aggagttgat caagtccatc aatgaaaagt ttgctgggtc tgctggctgg gaaggcacag   1380

aatcgctgaa gaagccagaa gacaaaaagc agctgggaga tttctttggc atgtccaaca   1440

gttatgcaga gtgctaccca gccacgatgg atgacatggc tgtggatagt gatgaggagg   1500

tggattatag caaaatggac cagggtaaca agaaggggcc cttaggccgt tgggactttg   1560

atacccagga agaatacagc gagtatatga acaacaaaga agctttgccc aaggctgcat   1620

tccagtatgg tatcaaaatg tctgaagggc ggaaaaccag gcgcttcaag gaaaccaatg   1680

acaaagcaga gcttgatcgc cagtggaaga agattagtgc aatcattgag aagaggaaga   1740

agatggaagc tgatggggtt gaagtcaaaa gaccaaaata ctaatcacta gttacaacca   1800

gagatgctcc acaaggatat gctccccact gttttctttc tacaatttcc aaaggttgca   1860

agatgttttt ttgtggatga atataaaatt ttattgtgta attacttggt tccattaaaa   1920

ttggttaact tgctaaaaaa aaaaaaaaaa aaaaa                              1955


<210>  812
<211>  1480
<212>  DNA
<213>  Human

<400>  812
ggtgactgac ggcgccggcc gcccctgccc gtcgcccgcc cgctgctgcc gcccgcccgg     60

ggtgtggagc ccggccgctg ctcgcgggct gagtgtctgt cgctgctgcc gcctccaccc    120

agcctccgcc atggacctct tcggggacct gccggagccc gagcgctcgc cgcgcccggc    180

tgccgggaaa gaagctcaga aaggacccct gctctttgat gacctccctc cggccagcag    240

tactgactca ggatcagggg gacctttgct ttttgatgat ctcccacccg ctagcagtgg    300

cgattcaggt tctcttgcca catcaatatc ccagatggta aagactgaag ggaaaggagc    360

aaagagaaaa acctccgagg aagagaagaa tggcagtgaa gagcttgtgg aaaagaaagt    420

ttgtaaagcc tcttcggtga tctttggtct gaagggctat gtggctgagc ggaagggtga    480

gagggaggag atgcaggatg cccacgtcat cctgaacgac atcaccgagg agtgtaggcc    540

cccatcgtcc ctcattactc gggtttcata ttttgctgtt tttgatggac atggaggaat    600

tcgagcctca aaatttgctg cacagaattt gcatcaaaac ttaatcagaa aatttcctaa    660

aggagatgta atcagtgtag agaaaaccgt gaagagatgc cttttggaca ctttcaagca    720

tactgatgaa gagttcctta aacaagcttc cagccagaag cctgcctgga aagatgggtc    780

cactgccacg tgtgttctgg ctgtagacaa cattctttat attgccaacc tcggagatag    840

tcgggcaatc ttgtgtcgtt ataatgagga gagtcaaaaa catgcagcct taagcctcag    900

caaagagcat aatccaactc agtatgaaga gcggatgagg atacagaagg ctggaggaaa    960

cgtcagggat gggcgtgttt tgggcgtgct agaggtgtca cgctccattg gggacgggca   1020

gtacaagcgc tgcggtgtca cctctgtgcc cgacatcaga cgctgccagc tgacccccaa   1080

tgacaggttc attttgttgg cctgtgatgg gctcttcaag gtctttaccc cagaagaagc   1140

cgtgaacttc atcttgtcct gtctcgagga tgaaaagatc cagacccggg aagggaagtc   1200

cgcagccgac gcccgctacg aagcagcctg caacaggctg gccaacaagg cggtgcagcg   1260

gggctcggcc gacaacgtca ctgtgatggt ggtgcggata gggcactgag gggtggcgcg   1320

cggccaggag cacgcatggt attgacttaa aaggttcatt ttgtgtgtgt gcacattgtg   1380

tgttttgtgt actcctgtgg gactcccatg gttgtaaata aaggtttctc tttttttttc   1440

ctaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa                         1480


<210>  813
<211>  15592
<212>  DNA
<213>  Human

<400>  813
gaaatctttt aggcctttag atgttgttct ggaaaaactt tagtaatgga tcaaaggaag     60

aatgagagta ttgttcctag tataactcaa ttagaagatt ttcttacaga acacaattcc    120

aatgttgttt ggctccttgt tgctaccatt ttgtcctgtg gatggattat ttacctcaca    180

tattataatt cccggaatgt tggtcttatt ttaacactag ttcttaacag attatacaag    240

catggctata tccatattgg ttccttctct ttctctgttc tttctggaaa agtcatggtt    300

cgtgaaatct attacattac agaagacatg tctattagga ttcaagatgg attcatcatt    360

tttcggtggt ggaaaatgta taacccaaaa cagaagcaac atgatccaaa ggcagaaacc    420

aggttataca tcacagtcaa tgactttgaa tttcatgtct ataatcgctc ggatctttat    480

ggacgccttc aagagttgtt tggtttggag ccaacaataa ttccacctaa gaaagatgat    540

gataaaacac gggaaattgg aagaacaaga acccaatcga aaattgaaag agttaaagta    600

aaaacagaat cccaagaccc cacatcttca tggagatcac ttattccagt cataaaggtc    660

aatgtgagca caggacgttt ggcctttgga aatcactacc agccgcaaac tctgtgcatc    720

aactttgatg atgctttctt aacttatact acaaaaccac cttcaagtca tcttgaccaa    780

ttcatgcata ttgtgaaagg aaagcttgaa aatgttcgag tcatgcttgt tcctagtcca    840

agatatgttg gtcttcaaaa tgatgaacca ccgagattaa tgggagaagg ttttgtggtg    900

atgcagtcaa atgatgttga catctactac tacatggatg agccaggact tgttccggaa    960

gaaacagaag aaaatattga aggagaaatg agcagtgagg attgcaaatt acaagacttg   1020

cctccatgtt ggggactgga tatagtttgt ggtaaaggaa cagattttaa ttatggacca   1080

tgggccgata ggcagagaga ttgtttgtgg aagtttttct ttccacctga ctatcaagtt   1140

ctgaaagttt ctgaaattgc acagcctggg agaccaagac agatccttgc ttttgaatta   1200

cgaatgaata ttattgcaga tgctacaatt gatttgctgt ttaccaaaaa tagggaaaca   1260

aatgctgtac atgtaaatgt aggagctggc tcatatttag aaattaatat tccaatgaca   1320

gttgaagaaa atggttacac tcctgctatt aagggacaac tcttacatgt ggatgccact   1380

accagcatgc aatatcggac ccttttagaa gcagaaatgt tagcattcca catcaatgcc   1440

agctaccccc gaatatggaa catgccgcag acatggcagt gtgaattaga ggtttataaa   1500

gccacttacc acttcatctt tgcacagaaa aacttcttta cagatttaat tcaagactgg   1560

tctagtgaca gtcctccaga cattttttca tttgttccat atacgtggaa ttttaaaatc   1620

atgtttcatc agtttgaaat gatttgggct gctaatcaac acaattggat cgactgttct   1680

actaaacaac aggaaaatgt gtatctggca gcctgtggag aaacactaaa cattgatttt   1740

tctttgcctt ttacggactt tgttccagct acatgtaata ccaagttctc tttaagagga   1800

gaagatgttg atcttcattt gtttctacca gactgccacc ctagtaaata ttctttattt   1860

atgctggtaa aaaattgcca tccaaataag atgattcatg atactggtat tcctgctgag   1920

tgtcaaagtg gccagaaaac agttaaacca aaatggcgca acgttactca ggaaaagtct   1980

ggttgggttg aatgctggac tgtcccaagt gtcatgctta caattgatta tacatggcat   2040

ccaatttatc cacaaaaagc agatgaacag ctgaaacaat cattatcaga aatggaagag   2100

acaatgctat ctgtattaag gccatcccag aagacatcag acagagttgt ttcttctccc   2160

tctacttctt cacgcccacc tattgatccc tcagaacttc cacctgataa acttcatgta   2220

gaaatggaac tttctccaga ttctcagata actctctatg gacctctact aaatgccttt   2280

ttgtgtataa aggaaaacta ctttggggaa gatgacatgt atatggattt tgaagaggtt   2340

atctcaagtc ctgttttgtc actgtcaaca tcatccagct ctgggtggac tgctgttgga   2400

atggaaaatg acaaaaagga aaatgaaggt tcagccaagt caattcatcc acttgccttg   2460

cgtccttggg atattactgt acttgttaat ttgtacaaag ttcatgggcg tcttcctgtt   2520

catggaacta ctgatggtcc tgaatgccct acagctttct tggaaagact atgttttgaa   2580

atgaaaaaag gatttaggga gaccatgctg caacttatcc tgtcacccct gaatgtgttt   2640

gtcagtgata actatcagca gcgaccccct gtggatgaag tactcaggga aggtcacatc   2700

aatttgtcag gtctccagct gagagcacac gctatgttct cagcagaagg tcttcctttg   2760

ggaagcgatt ccttagaata cgcatggtta attgatgtgc aggctggaag tcttacagct   2820

aaggtcacag caccacagct ggcatgcctc ttggagtggg gacagacatt tgtttttcat   2880

gtggtatgtc gggagtatga actggaaaga ccgaaatcag ttataatatg tcagcatgga   2940

attgatcgtc ggttctgtga atccaagttg agttgtattc ctgggccttg tccaacttca   3000

gatgatttga aatatactat gattcgttta gcagtagatg gagccgatat ttacattgtt   3060

gagcatggtt gtgctacaaa tataaagatg ggtgcaattc gagttgcaaa ctgtaatctc   3120

cacaatcaat cggttgggga aggaatcagt gctgcaattc aggattttca agtgagacag   3180

tacattgagc aattaaataa ttgcagaatt ggacttcagc ctgcagtgct acggagggcc   3240

tattggcttg aagctgggtc agccaattta ggacttatta ctgttgatat tgctttagct   3300

gctgaccatc attctaaaca tgaggcacaa agacatttct tagaaactca tgatgccaga   3360

actaagaggt tgtggttttt atggccagat gatatcctga agaataagag gtgtagaaac   3420

aaatgtggtt gtctcggtgg ctgcagattc tttggtggca cagtaactgg cctagatttc   3480

ttcaaacttg aagagttgac accttccagt agctctgcat tttcaagcac aagtgcagag   3540

tctgatatgt attatggaca gtctctgcta cagcctggag aatggataat tactaaagaa   3600

attcccaaaa ttatagatgg taatgtgaat ggcatgaaga ggaaagaatg ggaaaacaaa   3660

tcagtgggaa tagaagtaga gagaaaaact cagcacctta gtcttcaagt accattacga   3720

tctcatagtt catcctcttc ctcagaagag aacagtagtt ctagtgctgc acagcctttg   3780

ttggctggtg aaaaggaaag tccttcatct gttgctgatg accatttggt tcaaaaagag   3840

ttcttgcatg ggacaaaaag agatgatggc caagcaagta tccctacaga aatttcagga   3900

aacagccctg tgtctcctaa tactcaggat aagtcagtag gtcaatctcc tcttagatct   3960

cccttgaaac gacaagcctc tgtctgttcc acccgtcttg gaagtactaa gagtcttact   4020

gctgctttct atggggacaa gcagcctgta acagttggag tccagtttag tagtgatgtc   4080

tctcgaagtg atgagaatgt actagactca ccaaagcaga ggagaagttt tggttcattc   4140

ccatatacac catcagcaga ctctaattca tttcatcagt atcgatcaat ggattccagc   4200

atgtcaatgg ctgatagtga agcctacttt tctgctgctg aggaatttga gcccattagc   4260

agtgatgaag gccctggaac ttatccgggt agaaaaaaga agaaaaagca aacccagcag   4320

attgactaca gtaggggttc catatatcac agtgtagaag ggccacttac tggacatgga   4380

gaaagcattc aggattccag aactctgcca ttcaaaactc atccttctca ggcttcattt   4440

gtttctgcgt taggtggaga agatgatgtt atagaacatc tatatattgt agaaggtgag   4500

aaaacagtgg agagtgaaca gattactccg caacaacccg tgatgaattg ttatcagact   4560

taccttactc agttccaggt aattaattgg tcagttaagc acccaaccaa caaaagaacc   4620

tctaaatcct cattgcatcg tccccttgat ctggatacac caaccagtga agaaagttca   4680

tcgtcatttg aacagctttc tgttccaact tttaaggtta tcaagcaggg gctcacagct   4740

aattctttgc tagacagagg catgcaactt tcaggatcaa cttcaaatac gccgtatact   4800

ccattggaaa aaaaactcgc tgataacaca gatgatgaaa cattaacaga agagtggacc   4860

ctggatcaac cagtgtccca gaccaggaca acagccatag ttgaagtaaa aggaactgtt   4920

gatattgttt tgactcccct ggtggctgaa gctttagaca gatatattga agcaatggtt   4980

cattgtgcta gtacccgaca tccagctgca attgtagatg atcttcatgc taaagtcctc   5040

agggaagctg tccaaaatag caagactacc ttttcagaaa atttatcttc caaacaagac   5100

attagaggaa caaaaactga gcagtctaca ataggaacga ctaaccaagg acaagcacag   5160

acaaatctta caatgaagca agataatgta acaattaaag gtcttcagac taatgttagc   5220

ataccaaagg taaacttatg tttgttacaa gcctcagtgg aagaatctcc aactacggct   5280

cctagtagga gtgtgactca tgtttcccta gtggcattgt gttttgacag aattgctaca   5340

caggttcgca tgaacagagg tgtggttgaa gagacttcaa acaatgcaga acctggtaga   5400

acatcaaatt ttgataggta tgttcatgcc acaaagatgc agcctcagtc atctggatct   5460

ctcagatcaa atgctggagc agaaaaaggc aaagaaattg cagctaagtt aaacattcat   5520

cgagttcatg ggcaacttag gggtcttgat acaacagaca ttgggacctg tgcaatcact   5580

gctattcctt ttgagaagtc caaagtttta tttactcttg aagagttgga tgaatttact   5640

tttgtggatg aaactgatca gcaagctgtt ccagatgtaa ctcgaatagg tcccagccaa   5700

gaaaaatggg gatggataat gtttgaatgt ggacttgaaa atttaaccat aaaaggagga   5760

agacagtctg gtgctgtttt atataacagt tttggaatta tgggtaaagc tagtgacaca   5820

gaaaggggtg gagtgctgac atccaataat tcttctgatt ctccaaccgg cagtggctat   5880

aatactgatg tctctgatga taatcttcca tgtgaccgga caagcccttc ctcagactta   5940

aatggaaatt ctgtttcaga tgaacaggat gaaggagtcg aatctgatga tttgaaaaaa   6000

gatctacctc tgatgcctcc tcctccagat tcatgtagca tgaagttgac cattaaagaa   6060

atttggttta gttttgcagc tcccaccaat gtgagatctc acacacatgc attttctagg   6120

cagctgaacc ttttaagcac tgcaacacca gctgttggtg catggcttgt tcccattgac   6180

caactcaagt catctttaaa caaattggaa actgagggaa ccttgagaat ttgtgctgtt   6240

atgggatgca taatgacaga agcattagag aataaaagtg tacattttcc cctaagaagt   6300

aaatacaaca ggcttacaaa agttgctcgc tttctccaag aaaatccttc atgtttacta   6360

tgtaatatac tacaccacta tctgcaccag gcaaattact ccatcattga tgatgctaca   6420

atgagcgatg gacttcctgc tttggtaact ttgaagaaag gtttagttgc actggcaagg   6480

cagtggatga agtttattgt ggtgacacca gcctttaaag gagttagctt acatagacca   6540

gctcagcctc tgaaacctca aatagctatg gaccatgaac atgaagatgg acttggattg   6600

gacaatgggg gtggtcttca aagtgatacc agtgctgatg gagcagaatt tgagttcgat   6660

gcagccacag tcagtgaaca cacaatgcta ttagaaggaa cagctaaccg gcctccacct   6720

ggtagctctg gacctgtaac tggagctgag ataatgagga aactttctaa aactcatacc   6780

catagtgact ctgcattaaa aataaagggc attcacccat atcattctct gagctatacc   6840

agtggagaca ctgccactga ttctccagtg catgttggac gtgctgggat gccagtaaag   6900

gacagtccaa ggaaggagag cctactcagc tacctgactg gaagcttccc aagcctgcac   6960

aacctcctgg aaggtactcc tcagagaagc agtgctgctg tgaaaagtag ctccctaacg   7020

agaacaggaa atacagtagc cactgatatg ttatctgaac atcccttgct atctgagcca   7080

tcatctgtga gtttctataa ttggatgtca aatgctgtgg gtaatcgagg aagtgtgtta   7140

caagaatctc ctgttacaaa atcaggacac aatagtcttc ccacaggtgt tgcacccaat   7200

cttccaacaa taccctcagc ctcagatttc aacactgtct tgtctagtga ccaaaatact   7260

ttggatggga cacattctca gcatagcacc agtcaggatg atgtggcagg tgtagaagaa   7320

gcaaaccaag ggtttcctgc tgttcagctt gctgatgcac aggttgtttt caagcctctt   7380

ctgagtcata cagggatcca gtcacaggat acaatgccat tctgctaccg aatgtacttt   7440

ggagaacacc tttcattttc agggactttg gactgcctca gagcagatat tgtggattca   7500

gacacagcca aagagagaaa aggcaaaaga gcaagaaggc aaggccatgt gaatcttcct   7560

ccacttgagt tcaaaccagc attaatgttg ggaaccttta gcatcagtgc tgttgtaatg   7620

gaaaagtccg tgtgcacccc tcagaactct accagtgccc tttcttttca tgatctcagc   7680

aagcggtatt ataacacctt tcactgcaac tttactattt cctgtcagtc aataagccag   7740

catgtagata tggctttggt tcgtcttatt catcagttta gcacaatgat agatgacatc   7800

aaagcaactc agactgatat taaacttagc agatatacag ccggatctgc ttccccaaca   7860

cctaccttca aaaccagaaa acatcgggac tttcgttcat ctgactttag ccgcagttct   7920

agaggaagtc ttaatggtgg caatagagta aataatgcaa agaacaaacg gaccaacaat   7980

gagaataaca aaaaggaatc tcgaaacaag aattcattag gaagatctga aagaagaaca   8040

tcaaaagtgt ctaggaaagg ttcaaaagat gtggtggatc acatgactat tcatatggat   8100

gactctgatt caattacagt gtcagaacaa agtgagcctt cagctgagtg ctggcagaat   8160

atgtataaat tgcttaactt ctattcactt atctccgatc caacaggaat attggaaaag   8220

tcttcagaaa catttggacc agcaggagtt cggagcccta cagagccaac atgtaaagtt   8280

gtgtttgaga atgaacaaga caacagcagt ttgactaaga ctcagaggaa acgtagcttg   8340

gtaacttctg aacctcagca tgttactcta atagtgtttg ggattggcat ggtgaaccgc   8400

acacacctag aggcagatat tggtggacta acaatggaat cagaactgaa gaggatccat   8460

ggcagtttta ctcttaagga aaaaatgaaa gatgttttac atcaaaagat gactgagact   8520

tgtgctactg ctcatattgg tggggttaat attgtgctgc ttgaagggat tacaccaaat   8580

atacaactgg aggattttcc tacatctcct acaagtacag ccaaacaaga gtttctaact   8640

gtagtgaaat gtagtattgc caagtcccaa gccctctaca gtgcccaaag agggctgaag   8700

acaaacaatg ctgctgtgtt caaagtagga gctatcagta tcaacattcc tcagcaccct   8760

gccaccttac atagcatgat ggttcgaagt tctcaccaac tatctaaaca aatctcagac   8820

ctaatcagac agccttctac agccccacag cctgtaaaag aagatattgc aaccccacta   8880

ccttctgaaa aaaccccaac aagtgttaat caaactcctg ttgaaacaaa tgaatttcct   8940

cagctaccag aaggcttaga aaagaagcct attgttctta aattcagtgc catgttagat   9000

ggtatagcca ttggagcagc acttttacca tctctgaaag cagaatacaa gatgggaaga   9060

atgagaagtc atggaatgac aggtgcacag acaagattta catttgagct gccaaatcac   9120

agattgcgtt ttacttcaaa agtttctgcc acagatatgt caaccattcc tccttctgcc   9180

agtcttaacc ttccccctgt taccatgtca gggaaatata taatggaaga acatgatagt   9240

tattcggatc aggtgtggag tatagatgaa ctgccttcta aacaaggtta ctatttacag   9300

ggaaattatc tgcgttgtgt ggcagaagtt ggttcctttg aacataatct tacaactgat   9360

cttctaaacc acttggtatt tgtacagaaa gtgttcatga aggaagttaa tgaagtaata   9420

caaaaagttt ctggtgggga gcagcctatt cctctctgga acgaacatga tggaacagca   9480

gatggagata aacctaaaat tctcctctat tccctaaact tgcagttcaa gggtattcaa   9540

gtaacggcca ctactccatc aatgagagct gtaagatttg aaactggatt gattgaactg   9600

gaactttcta accgacttca aaccaaagct tcaccaggaa gtagcagcta tctgaaactg   9660

tttggcaaat gccaggtgga tttaaatctg gcattaggac aaattgtcaa acatcaggtt   9720

tatgaggaag ctggttctga ttttcatcaa gttgcctatt ttaaaaccag aattggatta   9780

agaaatgccc tccgagaaga aatcagtggt tcttcagata gggaagctgt gcttattact   9840

ttgaatagac caattgttta tgcacagcct gtggcctttg atagagctgt gctgttttgg   9900

ctgaattata aggccgccta tgacaactgg aatgaacaac gaatggcttt acataaggat   9960

attcatatgg ctacaaagga agtagtagat atgctacctg gtatccagca aacatcagcc  10020

caggcctttg ggactctttt tctccagctc actgtcaatg atctgggaat ttgcctacct  10080

atcacaaata ctgcacagtc taatcatact ggagaccttg acactggttc tgctttggta  10140

ttaaccattg aaagtactct catcactgca tgctcttcag agtctctggt tagcaaaggg  10200

catttcaaaa acttttgtat ccgttttgct gatggatttg agacatcatg ggatgactgg  10260

aaaccagaaa ttcatgggga tttagtgatg aatgcctgtg tagttccaga tggcacctat  10320

gaagtatgtt caagaactac aggacaagca gcagctgaaa gcagtagtgc tggaacctgg  10380

acactcaacg tattgtggaa aatgtgtggg attgatgttc acatggatcc taacattggc  10440

aaaaggctta atgctctggg caatactctt acaacactga caggagagga agacatagat  10500

gacattgctg acttaaattc agtgaacata gctgacctgt cagatgagga tgaagttgat  10560

actatgtctc ccactatcca tactgaagcc acagattatc gaagacaggc agcatctgct  10620

agccagccgg gagaacttag aggaagaaaa attatgaagc gtatagtgga tatcagagaa  10680

ctgaatgaac aggccaaagt aatagatgat ctgaaaaaat taggtgcaag tgaaggaacc  10740

ataaaccagg aaattcaacg ttaccaacag ttagaatctg tggctgtgaa tgacattaga  10800

agagatgttc gtaaaaaatt acggaggtcc agtatgcggg ctgcttccct aaaggataag  10860

tggggtttga gttacaaacc aagttacagc cgatcaaaaa gcatttctgc ttctggaaga  10920

ccacctctta agcgaatgga aagggcaagt tctcgagtag gagaaactga agagctccca  10980

gaaatccgtg tggatgcagc atctcctgga cctagagtaa cttttaatat ccaggataca  11040

tttccagagg agacagaact ggaccttttg tcagtaacca ttgaaggtcc atcccattat  11100

tcatcaaata gtgaaggatc atgttctgtg ttcagttctc ccaaaactcc aggaggcttt  11160

tcaccaggca ttcctttcca aactgaagag ggccgacggg atgacagttt gtcttctacc  11220

agtgaagatt ccgagaagga tgaaaaagat gaagaccatg agagggaaag gttttatatt  11280

tacaggaaac cctcacatac gtctcgtaaa aaagcaacag gctttgctgc tgttcatcag  11340

ctatttacag aacgctggcc aacaacacca gtcaatagaa gtcttagtgg cacagctaca  11400

gagagaaata ttgactttga acttgatata cgggttgaaa ttgatagtgg aaaatgtgta  11460

ctccacccaa ccacccttct acaagaacat gatgatataa gtttgagaag gagttatgat  11520

cgaagttcca ggagcttaga tcaagattca ccttcaaaaa agaagaagtt tcaaactaat  11580

tatgcttcta ccacccattt aatgaccggc aagaaagtgc catcatctct acagacaaag  11640

cctagtgact tagaaacaac agtattttac attcccggag ttgatgtaaa gttgcattac  11700

aattccaaga cgctaaagac tgaatcacct aatgcctcca ggggatcttc cttgccaaga  11760

acactgtcca aagagtccaa gctgtatggt atgaaagata gtgcaacatc tcctccttct  11820

cctcctttac cttccactgt ccagagcaag actaacacct tacttcctcc ccagccccca  11880

cctattcctg cagccaaagg aaaaggaagt ggaggagtaa aaacagccaa gttatatgcc  11940

tgggtagcac ttcagtcatt gccagaagaa atggttatta gtccctgcct attagacttt  12000

ctggaaaaag ctctggaaac tatcccaatt acaccagttg aaaggaatta tacagctgtc  12060

agctcacaag atgaagatat gggacatttt gaaataccag atcctatgga agaatcaaca  12120

acatcactag tgtcgtcttc aacatctgct tactcttcct tccctgtaga tgttgtggtt  12180

tatgtacgag ttcagccctc acagatcaaa tttagctgtt taccagtatc aagagtagaa  12240

tgcatgttaa agctgccatc cctggatttg gtgttttctt caaaccgagg agaactggag  12300

actttaggga ctacatatcc tgcagagact ttatcccctg gaggtaatgc tactcagagt  12360

ggaacaaaga cttctgctag caaaactgga ataccaggtt catcgggatt aggcagccct  12420

cttggccgaa gtcgacatag tagtagtcag tcagacctga ccagttccag cagtagttca  12480

tctggcttga gcttcactgc atgcatgtct gacttttccc tttatgtatt tcatccatat  12540

ggagcaggga aacaaaaaac tgctgtttct ggcctcacac ctggatcagg aggattaggg  12600

aatgtggatg aggagcccac ttcagtcact ggtcgaaaag attcactcag tataaacctt  12660

gagtttgtaa aagtgagttt gtcacggatc aggcgttcag gaggtgcctc attttttgaa  12720

agtcagtctg taagcaagtc tgcaagcaaa atggatacta cgttaataaa tatatctgct  12780

gtttgtgata tagggtctgc ctcctttaaa tatgatatgc gccgactcag tgaaattctg  12840

gcatttccaa gagcatggta tagaagaagt attgcaagac gtctattcct tggagaccaa  12900

actataaatt tgccaacatc tggcccaggg acacctgatt ccattgaagg ggtaagccaa  12960

cacctttccc ctgaatcatc aagaaaagct tactgcaaga cctgggagca gccaagtcag  13020

tcagcctcct tcacccacat gcctcagtca cctaatgtgt tcaatgagca tatgacaaac  13080

agcaccatgt caccagggac agtaggacag agcctaaaat ccccagcttc cataagatca  13140

aggagtgtat ctgattcttc agttcctcga agagattcac tttcaaaaac atcaactcct  13200

tttaacaaat caaacaaagc agcaagccaa caagggaccc catgggaaac acttgtcgtg  13260

tttgctatca acttgaagca attaaacgtt caaatgaata tgagtaatgt aatgggaaat  13320

acaacttgga caactagtgg tttgaagagc cagggccgtc tgtcagtagg aagtaatcgt  13380

gatcgagaga tcagcatgtc tgttggtctg ggaagatcac aattagattc taaaggagga  13440

gtagttggag ggaccataga tgtcaatgct ttggagatgg ttgctcatat ttctgaacat  13500

ccaaatcagc aacccagtca caaaattcag attactatgg gttctactga agctcgtgtt  13560

gattacatgg gctcaagtat cctcatgggc atcttcagta atgctgatct taagcttcag  13620

gatgaatgga aagtaaactt gtataataca ttggattcaa gcataactga taaaagtgag  13680

attttcgtcc atggagattt gaagtgggat attttccaag taatgatatc aaggtcaacc  13740

acaccagatc tgataaaaat aggaatgaag ctccaggaat ttttcacaca acaatttgat  13800

accagcaaac gagctctgtc tacctgggga ccagttcctt accttccgcc aaagacaatg  13860

actagcaacc tagaaaaaag ttcacaagaa caattacttg atgcagcaca tcatcgacac  13920

tggcctggag tattgaaggt ggtatcagga tgccacatat ccttatttca gattccatta  13980

ccagaagatg gaatgcaatt tggaggatca atgagcttac atggaaatca tatgacactg  14040

gcatgttttc atggtccaaa ttttcgttca aaatcttggg ccctttttca tttagaagaa  14100

ccaaatattg ctttttggac tgaagctcag aaaatctggg aagatggctc cagtgatcat  14160

tctacatata ttgtacaaac actagatttt cacctgggtc ataatactat ggttaccaaa  14220

ccatgtggtg ctttggaaag tcctatggca acaataacca agataacaag gcgtcgccat  14280

gaaaatccac cccatggagt agcaagtgtg aaagaatggt tcaattatgt tacagctaca  14340

aggaatgaag agctaaatct gcttcgtaat gttgatgcta acaacactga gaatagcact  14400

actgtgaaga attctagttt gttgagtgga ttcagaggag gttctagcta caaccatgaa  14460

acagagacta tctttgcatt accaaggatg cagcttgact ttaaatccat tcatgttcaa  14520

gaaccacagg agccttcatt acaggatgcc agcctgaagc caaaagtaga atgtagtgtg  14580

gtgacagagt tcactgacca catttgtgtg actatggatg ctgagctcat catgtttctt  14640

catgatttag tatcagctta tcttaaagaa aaagaaaaag ccatctttcc acctcggatt  14700

ttatctactc gaccaggaca aaaaagtcca attattatac atgacgacaa ttcctctgat  14760

aaagatagag aagatagcat cacttatact actgtggact ggagagattt tatgtgcaat  14820

acatggcatc tagaacctac tcttagatta atttcttgga ctggaagaaa gattgatcca  14880

gtaggtgttg attatattct tcaaaaattg ggctttcatc atgctaggac tactattcct  14940

aaatggcttc aaagaggagt catggatcca ctggacaagg ttctgtcagt tcttatcaaa  15000

aagctcggta ctgcactaca ggatgaaaag gaaaagaaag gcaaagacaa agaagaacac  15060

taaaaaagta atttgatctg tgaacaaatt atgattgtgt ctgttttatt acactggagt  15120

gtttttttag tataataatt tgaaatataa ctttaaaata attctaaatt tgtggctata  15180

attaaaagtt tgtaagttaa cctgttctag ttccatcatt ctgtgtacag tgaagtattg  15240

catgataatg taaattttgt gaaaaactag attaaaatat ataactgctt gttatggttt  15300

ataattatat aatgtgcaat acaattcctg catctttaaa atgtctgcag aataactgtg  15360

aatttttttg ttattggatt ggccgtaact tttagaaaaa aatcttgttg atgataatgt  15420

gattttgggg aggtcattaa ttgctttttc ttttttaaat gtagacttat ataaatacct  15480

gtttgtatat agcttgagta attgtgatat gattgtatac cactaaaata ttgttaacta  15540

ttataataaa gtcacagtaa tggtttaagt ctgtaaaaaa aaaaaaaaaa aa          15592


<210>  814
<211>  1901
<212>  DNA
<213>  Human

<400>  814
acaggccttt ccttacctcc ctccatgctg tccacttcct ctgtaaagct ctcaaccctg     60

tccccttccc cctctctcct gggaaagagc cctcccatgc ctagctgctg ctcttaggga    120

ccctgtggct aggtgcgcgg atggaaatcc aggatctccg cctggttcgg cccgcctgcc    180

tccactcctg cctctaccat gtccatcagg gtgacccaga agtcctacaa ggtgtccacc    240

tctggccccc gggccttcag cagccgctcc tacacgagtg ggcccggttc ccgcatcagc    300

tcctcgagct tctcccgagt gggcagcagc aactttcgcg gtggcctggg cggcggctat    360

ggtggggcca gcggcatggg aggcatcacc gcagttacgg tcaaccagag cctgctgagc    420

ccccttgtcc tggaggtgga ccccaacatc caggccgtgc gcacccagga gaaggagcag    480

atcaagaccc tcaacaacaa gtttgcctcc ttcatagaca aggtacggtt cctggagcag    540

cagaacaaga tgctggagac caagtggagc ctcctgcagc agcagaagac ggctcgaagc    600

aacatggaca acatgttcga gagctacatc aacaacctta ggcggcagct ggagactctg    660

ggccaggaga agctgaagct ggaggcggag cttggcaaca tgcaggggct ggtggaggac    720

ttcaagaaca agtatgagga tgagatcaat aagcgtacag agatggagaa cgaatttgtc    780

ctcatcaaga aggatgtgga tgaagcttac atgaacaagg tagagctgga gtctcgcctg    840

gaagggctga ccgacgagat caacttcctc aggcagctat atgaagagga gatccgggag    900

ctgcagtccc agatctcgga cacatctgtg gtgctgtcca tggacaacag ccgctccctg    960

gacatggaca gcatcattgc tgaggtcaag gcacagtacg aggatattgc caaccgcagc   1020

cgggctgagg ctgagagcat gtaccagatc aagtatgagg agctgcagag cctggctggg   1080

aagcacgggg atgacctgcg gcgcacaaag actgagatct ctgagatgaa ccggaacatc   1140

agccggctcc aggctgagat tgagggcctc aaaggccaga gggcttccct ggaggccgcc   1200

attgcagatg ccgagcagcg tggagagctg gccattaagg atgccaacgc caagttgtcc   1260

gagctggagg ccgccctgca gcgggccaag caggacatgg cgcggcagct gcgtgagtac   1320

caggagctga tgaacgtcaa gctggccctg gacatcgaga tcgccaccta caggaagctg   1380

ctggagggcg aggagagccg gctggagtct gggatgcaga acatgagtat tcatacgaag   1440

accaccagcg gctatgcagg tggtctgagc tcggcctatg ggggcctcac aagccccggc   1500

ctcagctaca gcctgggctc cagctttggc tctggcgcgg gctccagctc cttcagccgc   1560

accagctcct ccagggccgt ggttgtgaag aagatcgaga cacgtgatgg gaagctggtg   1620

tctgagtcct ctgacgtcct gcccaagtga acagctgcgg cagcccctcc cagcctaccc   1680

ctcctgcgct gccccagagc ctgggaagga ggccgctatg cagggtagca ctgggaacag   1740

gagacccacc tgaggctcag ccctagccct cagcccacct ggggagttta ctacctgggg   1800

accccccttg cccatgcctc cagctacaaa acaattcaat tgcttttttt ttttggtcca   1860

aaataaaacc tcagctagct ctgccaatgt caaaaaaaaa a                       1901


<210>  815
<211>  6644
<212>  DNA
<213>  Human

<400>  815
gtgaccccag gccctggtca ctccatgctt tggagggtgc ttttgtcaaa gaggcctcct     60

ttccctcacc cagagctgga tttccaagag gctcccatac ctagctgccc tggcagactc    120

ccagggagga aaaacagcgt ggccttggca gctgccccga ggaaggagcc cacaggtgac    180

agggagaagc cattgccatt ccctgtcctg gcccccttca gcaaccctga acactctgct    240

ccagccaagg tggtgagggc agctgttcct aaacagcgca aaggcagcaa ggttggtgac    300

tttggagatg caatcaattg gcccacacct ggagagatag cccacaagag tgttcagcca    360

cagtcccaca agcctcagcc tacccgtaaa ctgccaccca agaaggacat gaaggaacag    420

gagaaaggag aagggagtga tagtaaggag agtccaaaaa ccaaatcaga tgaatcaggg    480

gaggaaaaga atggagatga ggattgccag cgaggcgggc agaagaagaa aggaaacaaa    540

cacaagtggg ttccattaca aatagacatg aagcctgaag tgcccagaga gaaactggct    600

tcacgcccca ctcgcccacc ggagcctaga cacatacctg ccaatcgcgg agagatcaaa    660

gggtctgagt ctgccaccta cgtgcccgtg gcccccccca ccccagcctg gcaaccagag    720

atcaaaccgg agcctgcctg gcacgaccag gatgagacat cgagtgtgaa gagtgatggg    780

gctggtgggg cgcgggcttc cttccgtggc cgtggacggg ggcgtggtcg cggccgggga    840

cgcggccggg gtggcactcg aacccatttt gactaccagt ttggctaccg aaagtttgat    900

ggtgtggagg ggcctcgtac gcccaagtac atgaacaaca tcacctacta ctttgacaat    960

gtcagcagca ccgagcttta cagtgtggat caggaactgc tcaaagacta catcaagcgc   1020

cagattgaat actacttcag cgtggacaat ttagagcgag acttcttcct gcgaaggaaa   1080

atggatgctg atggtttcct acccatcacc cttattgctt ccttccaccg agtgcaggcc   1140

cttaccactg acatttcact catctttgcg gccctaaagg acagcaaggt ggtggagatc   1200

gttgatgaga aagttcgtag gagggaggaa ccagaaaagt ggcctcttcc cccaatagtg   1260

gattattcac agactgattt ctcccagctt ctcaactgcc ctgaatttgt tccccgtcag   1320

cactaccaaa aggagacaga gtcggcacct ggctctcctc gtgcagtcac cccagtgcca   1380

accaaaacag aggaggtcag caacctaaag acactaccca agggcctgtc tgccagcctg   1440

cctgacctgg attctgagaa ctggattgaa gtgaagaaga ggcctcggcc atccccagca   1500

cggcccaaga agtcagagga gtccagattt tcccacctga cctctctgcc tcagcagctg   1560

ccttcccagc agctgatgtc caaggatcag gatgagcaag aggaactgga ttttctgttt   1620

gacgaggaga tggagcagat ggatgggcgg aagaacacct tcactgcctg gtctgatgag   1680

gaatctgact atgagattga tgacagggat gtcaacaaga tcctcattgt cacccagaca   1740

ccacattaca tgcgccggca cccagggggg gaccgcacag gcaaccacac ctcgcgtgcc   1800

aagatgagcg ccgaactggc caaggtcatt aatgatggcc tcttctacta tgagcaggac   1860

ctgtgggctg aaaagtttga acctgagtat tcccagatca agcaagaagt cgagaacttc   1920

aaaaaggtca atatgatcag ccgggagcag tttgacacac tgacccctga gccccctgtg   1980

gatcccaacc aggaagttcc tcctgggcca cctcggttcc agcaagttcc tacggatgcc   2040

ctggccaaca agttgtttgg tgctcctgag ccctccacca tcgcccgctc tctaccaacc   2100

actgtcccag agtcaccaaa ctaccgcaac accaggaccc ctcgcactcc ccggacacca   2160

cagctcaaag actcaagcca gacatcacgg ttttacccag tggtgaaaga aggacggaca   2220

ctggatgcca agatgcctcg aaaaagaaag acaagacaca gttcaaaccc acccttggag   2280

agccatgtgg gctgggtgat ggattcccgt gagcacaggc cccgtactgc ttccatcagc   2340

tccagcccct cagaagggac gcctacagtt ggcagctatg gctgtacccc tcagtcattg   2400

cccaagttcc agcatccttc ccatgaactg ctcaaggaaa atggcttcac acaacacgtc   2460

taccataagt atcgtaggcg ctgccttaat gagcggaaac gcttgggcat tggccagtct   2520

caggagatga acacactctt ccgcttctgg tccttcttcc tccgagatca cttcaacaaa   2580

aagatgtatg aggagttcaa gcagctggct ctggaggacg ccaaagaagg ctacagatat   2640

ggtttggagt gcctttttcg atactacagt tatggcctgg aaaagaagtt ccggctggac   2700

atattcaagg attttcagga ggaaacggtg aaggactatg aagctggcca actgtatggg   2760

ctggagaagt tctgggcctt cttgaaatat tccaaagcca aaaatttgga cattgacccc   2820

aaactgcaag aatacctcgg caaattccga cgtcttgaag acttccgagt agatcccccc   2880

atgggtgagg agggcaacca caagcgacac tcagtggtag caggaggtgg cggcggtgag   2940

ggcaggaagc ggtgcccctc ccagtcttcc agcaggcctg ctgccatgat cagccaaccc   3000

cctacaccac ccaccggcca gcctgtccgg gaagatgcca aatggacaag ccagcactcg   3060

aacacacaga ctttgggaaa gtgaaaagct ccttagccct ggggcttgag gggggaaagg   3120

ggtagggtgg gtaagagtcc atgggggtgc ccagtcccag gagaggggac aatgaaggga   3180

caggcctgga gttactagga caggcctttg tgctgagtag caatgtatac accatttggg   3240

ctatcagagg tacccctggg caggagcctc tacatcccct tccccctcct ctctccatga   3300

ctcttgacat cctagcttct tctaaggggg gagggaaagg ggggagattt ttatatatat   3360

atacatatat atatatcaag ttttaaatta ttgatagttc atctggatta ccaaaatcac   3420

tctgcagccc tgcccgaggc tagtaggctg caaccctggt ccccacccct aacctcctgc   3480

tccccctcaa gccaactatg cagcccacaa gaaggccctg cgggcccccc cattgcccag   3540

cactgtctca tagaaggctc tggtggtacc tctgggcccc aggagcatca gccccttgat   3600

catctggggt ttgtcatcac catattttct ccctgctgtt cccaccatgc ccttctgcca   3660

tcttctggga gaaggaaacc aaaggatcta aaactggggt ttgggggaag gtttcagcct   3720

ctccccactc cccttgcccc acacccttta ctccccagcc cagagagacg ctgcttttac   3780

caggaaagac tattgaaaga tgttttattt tatttttctc tgacctttcc atccttgaaa   3840

aaatggggaa aaaagaagaa aaaagacaaa atcgaccata aaagaccaaa aaaaaaaaaa   3900

aaatcagaaa acccccacct aatccacaga aagtaatgtc tttcccctcc ccttggaatt   3960

tttgttttgt ttttggaaat aatatttttt taaaagttgc cttattgtgg agcgggaatc   4020

tgaaataccc aaatgcctgt tttcctcggt ggagtcaacc cgaagagctc ccaccttctc   4080

tggatgtgcc tgggcttgga ctggctagaa tctttctctg gactgttgca tgtacagtgc   4140

ctccatcctg gaggcaagag agttgggagt ggctcgaatc agagccgtgc ccaagatatc   4200

cctgctgttg catcgtttga agctgacgtc ctgtgtctgt acactgctgc cactgttgtg   4260

tcctcgctct gcttgctgtt gcctcacgcc aggccccgtc ctgccgtgac acccttcatc   4320

ctacccttgg aaccccaagg ccaagttggt tcaaactgtt ggagaacaga gttggcctgc   4380

atctggaaca cacttgtcct cagcttacca tctcctcaca ccccagagtg gaaaggtgaa   4440

cacctgcagc tgaggcttgg aaacgtttct tgtgttgccc tgaaaaatct ttgagacctc   4500

agggaggctc tgtctctctt aaaaggtgga gaaagatgcc attctctccc taaggtctgg   4560

tggagtctcc ccatcttgca tacccttctg caagccatct atctctgctc actctccaat   4620

tgacccgcct gggaacaagg gatgaggagg agttgggggc tggggggaat cctgccagtt   4680

ggtgaagccc tgtggcagga aggtatatgt ggacatagag tatacctgat tctctttctt   4740

cagccactga ctgcttgggt tgggctgtga atgataatgg aatggctgga gtctgctgtt   4800

gtcagaaggc agggagggtg atgaaggact gacccacatg gactgggatg tgtgtcggtt   4860

atgggcatga ctgcacgttc actctcagtg ggatctgggc aacatggagt tcattgtcct   4920

gttgcttact tactgcaatg tctttggccc tccttttcaa ctggttcctc tgttgggccc   4980

aaaggttggg agtaggagac agtatcccag gctgacaagg gcttgccctt taccttgggc   5040

accttgttaa tttttagcct gtgcccttcc ccacctttgc cctcccagtg gttggtatgt   5100

gggaagccca tctcagttcc tgtgacttca tgtctcaaac caaggatgag cgtctggtct   5160

ctgctatgat ggtggtatcc gaggcctttc cctgcccagt ctggtgcctg ccccacattg   5220

taccggacac tggattcctg gacccccttc tcctttcctt tctttccttc aggtcacgca   5280

gccctgtact gtatccagca ccacagaaac ctcagtgttt ttcctctgct ggtttggggc   5340

acaaggaagc cttagggtat ggggaaaggc tgttattacc tagagtttac tcccaggcca   5400

gggggctgcc atcttcttca cagacatccc tgaaaggaag cccctttggg gcagggaggt   5460

gaggacttca tctcaacatc ggctggtggt tggtagggga gctttttctt ttctttcctt   5520

tttttttgtt tttgtttttg tttttgtttt tggtaacatg ttaggagtta atgttgcaaa   5580

gagtagttta catcttcact ttctgaagac acttgaattt aggaccgatg tatctgtgac   5640

aagcatgcca gaagtggcag gggccatcag ggctaaccac ttcacaccta ccatcgtccc   5700

atggggatcc aagacctgag ataaagcaac agcctgccca gatccctctg ttcatcctat   5760

cccttccaag gttggtccat gccaacataa cctctgggca tcagacatca gcaggtctgt   5820

gtgcctcagc cctgttaagg ggcaggtttc tctttagccc tcttcctgca cttgggagca   5880

aaggcactac cagtagagaa gggccatcca gccgtgcccc agcctggacc cctggggctc   5940

agatagaggt gctgagcccc tgtgtcaaag ttgttaaatg tttttgtttt gttccattgt   6000

agctcttttt tttttttttt cccctttcct ggtgattgat tttacaaaag aaagtaagct   6060

gcttagaagg ccctggaagg gaagtgagga ggagggacaa ggaagatgac tagttacgga   6120

gggtgagggt tgttttttgc caaaaagcct gggtagagtg atctgaatta tctggcaccc   6180

tcctgaatgg aaccccagag tacctcctgt gtggaagggt ccctggattt tccctaacac   6240

ccaccctctc ccccttcagc catgctgatg gcagagaaga taagaacttg gagcccattt   6300

ctcactggag aggaaaactt gtcatctggc tttgcggaga aggttccacc ttacgctcgt   6360

agtacattat ctttactatg tgctaggata tcatatttaa aaggacaaaa aaatgtaaaa   6420

tacttgaatg agcttgtatt ataacattaa tattattgag agtatctgct ttccaggctg   6480

aagtgattca ttcattattc tagtcctgct ttagtccttt gtaatttgtg gtaattatgc   6540

ttttcttttt aatacaaaaa aatgtataaa aataaacact tgaaaaggca aaaaaaaaaa   6600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa                    6644


<210>  816
<211>  3420
<212>  DNA
<213>  Human

<400>  816
ggagcggggg ataaggttac cacgcccgcg gtggccgggg acactctgag tttcgcgtgt     60

ggcttttagg gacgtttata tttgaatttc cctgaaccgc cgagtgtggg cggtggcgca    120

gatccgtccc ggaaacctcc gggctccttc ccgcctttct caggcccggc ccctccaagg    180

ggtccccgcg gggcggcggg agggccctgg gcccagagcc gcgcgggtgg gcagtcccag    240

gcgtccttcc ttacagccct gagcctggtc cgggaaccgc ccagccggga gggccgagct    300

gacggttgcc caagggccag attttaaatt tacaggcccg gcccccgaac cgccgaagcg    360

cgctgcctgc tccccattgg cccatggtag tcacgtggag gcgccggggc gtgccggcca    420

tgttggggag tgcggcgccg cggcccgcgc cacctccgcc ccccgcggct tgcctccagc    480

ccgcccctcc cggccctcct ccccccgccc gccgctccgt gcagcctgag aggaaacaaa    540

gtgctgcgag caggagacgg cggcggcgcg aaccctgctg ggcctccagt caccctcgtc    600

ttgcattttc ccgcgtgcgt gtgtgagtgg gtgtgtgtgt tttcttacaa agggtatttc    660

gcgatcgatc gattgattcg tagttccccc ccgcgcgcct ttgccctttg tgctgtaatc    720

gagctcccgc catcccaggt gcttctccgt tcctctaaac gccagcgtct ggacgtgagc    780

gcaggtcgcc ggtttgtgcc ttcggtcccc gcttcgcccc ctgccgtccc ctccttatca    840

cggtcccgct cgcggcctcg ccgccccgct gtctccgccg cccgccatgg cgactgcgac    900

ccccgtgccg ccgcggatgg gcagccgcgc tggcggcccc accacgccgc tgagccccac    960

gcgcctgtcg cggctccagg agaaggagga gctgcgcgag ctcaatgacc ggctggcggt   1020

gtacatcgac aaggtgcgca gcctggagac ggagaacagc gcgctgcagc tgcaggtgac   1080

ggagcgcgag gaggtgcgcg gccgtgagct caccggcctc aaggcgctct acgagaccga   1140

gctggccgac gcgcgacgcg cgctcgacga cacggcccgc gagcgcgcca agctgcagat   1200

cgagctgggc aagtgcaagg cggaacacga ccagctgctc ctcaactatg ctaagaagga   1260

atctgatctt aatggcgccc agatcaagct tcgagaatat gaagcagcac tgaattcgaa   1320

agatgcagct cttgctactg cacttggtga caaaaaaagt ttagagggag atttggagga   1380

tctgaaggat cagattgccc agttggaagc ctccttagct gcagccaaaa aacagttagc   1440

agatgaaact ttacttaaag tagatttgga gaatcgttgt cagagcctta ctgaggactt   1500

ggagtttcgc aaaagcatgt atgaagagga gattaacgag accagaagga agcatgaaac   1560

gcgcttggta gaggtggatt ctgggcgtca aattgagtat gagtacaagc tggcgcaagc   1620

ccttcatgag atgagagagc aacatgatgc ccaagtgagg ctgtataagg aggagctgga   1680

gcagacttac catgccaaac ttgagaatgc cagactgtca tcagagatga atacttctac   1740

tgtcaacagt gccagggaag aactgatgga aagccgcatg agaattgaga gcctttcatc   1800

ccagctttct aatctacaga aagagtctag agcatgtttg gaaaggattc aagaattaga   1860

ggacttgctt gctaaagaaa aagacaactc tcgtcgcatg ctgacagaca aagagagaga   1920

gatggcggaa ataagggatc aaatgcagca acagctgaat gactatgaac agcttcttga   1980

tgtaaagtta gccctggaca tggaaatcag tgcttacagg aaactcttag aaggcgaaga   2040

agagaggttg aagctgtctc caagcccttc ttcccgtgtg acagtatccc gagcatcctc   2100

aagtcgtagt gtacgtacaa ctagaggaaa gcggaagagg gttgatgtgg aagaatcaga   2160

ggcgagtagt agtgttagca tctctcattc cgcctcagcc actggaaatg tttgcatcga   2220

agaaattgat gttgatggga aatttatccg cttgaagaac acttctgaac aggatcaacc   2280

aatgggaggc tgggagatga tcagaaaaat tggagacaca tcagtcagtt ataaatatac   2340

ctcaagatat gtgctgaagg caggccagac tgttacaatt tgggctgcaa acgctggtgt   2400

cacagccagc cccccaactg acctcatctg gaagaaccag aactcgtggg gcactggcga   2460

agatgtgaag gttatattga aaaattctca gggagaggag gttgctcaaa gaagtacagt   2520

ctttaaaaca accatacctg aagaagagga ggaggaggaa gaagcagctg gagtggttgt   2580

tgaggaagaa cttttccacc agcagggaac cccaagagca tccaatagaa gctgtgcaat   2640

tatgtaaaat tttcaactgt cttcctcaaa ataaagaagt atggtaatct ttacctgtat   2700

acagtgcaga gccttctcag aagcacagaa tatttttata tttcctttat gtgaattttt   2760

aagctgcaaa tctgatggcc ttaatttcct ttttgacact gaaagttttg taaaagaaat   2820

catgtccata cactttgttg caagatgtga attattgaca ctgaacttaa taactgtgta   2880

ctgttcggaa ggggttcctc aaattttttg actttttttg tatgtgtgtt ttttcttttt   2940

ttttaagttc ttatgaggag gggagggtaa ataaaccact gtgcgtcttg gtgtaatttg   3000

aagattgccc catctagact agcaatctct tcattattct ctgctatata taaaacggtg   3060

ctgtgaggga ggggaaaagc atttttcaat atattgaact tttgtactga atttttttgt   3120

aataagcaat caaggttata atttttttta aaatagaaat tttgtaagaa ggcaatatta   3180

acctaatcac catgtaagca ctctggatga tggattccac aaaacttggt tttatggtta   3240

cttcttctct tagattctta attcatgagg agggtggggg agggaggtgg agggagggaa   3300

gggtttctct attaaaatgc attcgttgtg ttttttaaga tagtgtaact tgcttaaatt   3360

tcttatgtga cattaacaaa taaaaaagct cttttaatat tgaaaaaaaa aaaaaaaaaa   3420


<210>  817
<211>  3994
<212>  DNA
<213>  Human

<400>  817
gcccgctcca gccgccgcgc atcctcggcc cgcgccccga gacccgcgcc cagctagccc     60

cggccccgct cggcgcccca ggcagctcgg ctgcgctcgc cgcgggacgg cgcggccatg    120

aggctgcggg gatgcggacc ccgggccgcc cctgcctcca gcgcaggggc cagcgacgct    180

cggctgctgg cgcccccggg gcggaacccc ttcgtgcacg agctgcgcct cagcgccctg    240

cagaaggccc aggtggccct catgacactg acgctcttcc cggtccggct cctggttgcc    300

gctgccatga tgctgctggc ctggcccctc gcacttgtcg catccctggg ctctgcggag    360

aaggaacccg agcagccccc ggccctgtgg aggaaggttg tggacttcct gctgaaggcc    420

atcatgcgca ccatgtggtt cgccggcggc ttccaccggg tggccgtgaa ggggcggcag    480

gcgctgccca ccgaggcggc catcctcacg ctcgcgcctc actcgtccta cttcgacgcc    540

atccctgtga ccatgacgat gtcctccatc gtgatgaagg cagagagcag agacatcccg    600

atctggggaa ctctgatcca gtatatacgg cctgtgttcg tgtcccggtc agaccaggat    660

tctcgcagga aaacagtaga agaaatcaag agacgggcgc agtccaacgg aaagtggcca    720

cagataatga tttttccaga aggaacttgt acaaacagga cctgcctaat taccttcaaa    780

cctggtgcat tcatccctgg agcgcccgtc cagcctgtgg ttttacgata tccaaataaa    840

ctggacacca tcacatggac gtggcaagga cctggagcgc tggaaatcct gtggctcacg    900

ctgtgtcagt ttcacaacca agtggaaatc gagttccttc ctgtgtacag cccttctgag    960

gaggagaaga ggaaccccgc gctgtatgcc agcaacgtgc ggcgagtcat ggccgaggcc   1020

ttgggtgtct ccgtgactga ctacacgttc gaggactgcc agctggccct ggcggaagga   1080

cagctccgtc tccccgctga cacttgcctt ttagaatttg ccaggctcgt gcggggcctc   1140

gggctaaaac cagaaaagct tgaaaaagat ctggacagat actcagaaag agccaggatg   1200

aagggaggag agaagatagg tattgcggag tttgccgcct ccctggaagt ccccgtttct   1260

gacttgctgg aagacatgtt ttcactgttc gacgagagcg gcagcggcga ggtggacctg   1320

cgagagtgtg tggttgccct gtctgtcgtc tgccggccgg cccggaccct ggacaccatc   1380

cagctggctt tcaagatgta cggagcgcaa gaggacggca gcgtcggcga aggtgacctg   1440

tcctgcatcc tcaagacggc cctgggggtg gcagagctca ccgtgaccga cctattccga   1500

gccattgacc aagaggagaa ggggaagatc acattcgctg acttccacag gtttgcagaa   1560

atgtaccctg ccttcgcaga ggaatacctg tacccggatc agacacattt cgaaagctgt   1620

gcagagacct cacctgcgcc aatcccaaac ggcttctgtg ccgatttcag cccggaaaac   1680

tcagacgctg ggcggaagcc tgttcgcaag aagctggatt aggacccagg gttgcggaga   1740

gacgcggccc ctcccgcgtg gacatcaccg ccatgagcct ctttgcgagt gacctctggg   1800

ctccgctcct cactcctgct gtacaggcac tgtcttcagc ccgagttcca ggggcctcgg   1860

gggctgtttg tatcttgttc ctttgtgaag tgtgttgcag aaccgacgct tactgtgcga   1920

gaatcggagg gcgcgcacgc ggatcccccg cctggcctgg accccgtggg gtcaggttcc   1980

ctgccgggcg gggggcaccg gtgccgcccc gtgttctccc acggggccct ggtttcgagt   2040

ctctgtcaca gcctcttccg gcggcagcgt gcaccgggcg ggcctccgtg cacactcagc   2100

acacgcctgc cacacagcgt gcgcttgcgt gtcactctgg cacgaaacct gtctgcctct   2160

gtggatccac agcctggcag agccgagccg tcacctgatt tttcagtgtt tctacctgtg   2220

tgctggagct catgagtatt ttataaactc catttaggta cttcaggaaa catgcagcat   2280

tttttaaaaa atgaaaattg tttttctact tcatttttcc ttttagagtc aaaggatatt   2340

tatttatagg cctttttttt tttaatatag aatctgaggc tgtttgggct ttgacttaaa   2400

tttccatcag gcctctctcc agcaggtaat ccctctcctt ccgctgggtc ccctggggag   2460

gtgtgaactc aagggcctag ccccaaaaca ctttttctgc ttttcttaat ccttttccag   2520

tcccctcttt ttttataaac gttggcagtt tgatgtttct gtttcggcat aacgtaatcc   2580

atttcactgt agcctaaact ccagtccgag gttggatatt gttcaaatga gcagggcccg   2640

agctggaagc gcaaggcagc cgccgccgtg ccgctcctcc cttgccctca ggccaggtcc   2700

ctgctggaag cggctgcatc ttcctgtcag ccctggtttc catggtgact ggcgtcacgc   2760

agccacccga gtatggctga ccttcctgca gagagaggag ccgcagtctt ttgcttgtgg   2820

aaggagacgc tgggctgtgc ggtgcggagg gtgatgagga tgtctggtga cagccgtgcg   2880

gacaccactc ctctctgcag cactgcctcc cagcgccagg gtcgcgggca catcccactg   2940

agagcggggg tcctgcccca tcttagagtc aaaggcagag gggcttccag gccctggatg   3000

gggtattttg gtgtcacctg aagtccctct gacatcacct tgtttcatca ttttttatga   3060

cagaattaga aacccatcct tcaagcacaa taatcatcac agacttgagt ttgcttccta   3120

aagcaaaggc tccgggtttg tttggaaaat ttttttgatt tctgaaatga attgattttt   3180

atatttgggg catctctata gaaagtgacc accaaggcca gtaagtacgg gaaaaaatgt   3240

ttactaactt cctcagagat tcgtgatacg cgtttctcca ctgacagaca tttaaaaaca   3300

accttcagct ccgtttcaat caatcacctc gacttgtttt ttagcatgga cactgccagc   3360

aggacagaca gggatggagt aaaccgaagt caatttcagg gctcttggcg tgttggacac   3420

agaagaaatc ctagtgcagc ctttggtagc taacagtcac tgattttata attggagaat   3480

gcgtaaagat tcatttttca aggagaagag cctgcaaatg gccaatgaag gaggtaaata   3540

aactaagata ttccgaggga agggacccag gccacctccc ttccgcaggt ctgcagatga   3600

agggtttttt gaatgaaatg ccactgtgca ttttcagaaa aaaaaatctc tgataaacag   3660

actttgaatg gatgtttgtt cctcctgatt ctcttttctc ttcgtggcga cttagagttg   3720

gcggatattc ggaactgtga atgtacatag cgttgagtta aaccccttgt gtgtgagaca   3780

ggacgcagcg ggcccctggt ggcctggggg ccagacccgt gggcaggtgg ggcatgggcc   3840

ctggcctgcg gggacctgct ggggtgtgag ggcagaggga gggttgccat gaaggaactt   3900

gggattttca atggaataag taaaacataa agtctatact tgggaaaaaa aaaaaaaaaa   3960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa                               3994


<210>  818
<211>  2080
<212>  DNA
<213>  Human

<400>  818
ggagggcagt ctccgagttt cggaggggct tggagtgagt ggacgcactc gggaattgta     60

ggaggacgag gctcagctct tgccaggcca aattgagaca tgtctgacac aagcgagagt    120

ggtgcaggtc taactcgctt ccaggctgaa gcttcagaaa aggacagtag ctcgatgatg    180

cagactctgt tgacagtgac ccagaatgtg gaggtcccag agacaccgaa ggcctcaaag    240

gcactggagg tctcagagga tgtgaaggtc tcaaaagcct ctggggtctc aaaggccaca    300

gaggtctcaa agaccccaga ggctcgggag gcacctgcca cccaggcctc atctactact    360

cagctgactg atacccaggt tctggcagct gaaaacaaga gtctagcagc tgacaccaag    420

aaacagaatg ctgacccgca ggctgtgaca atgcctgcca ctgagaccaa aaaggtcagc    480

catgtggctg atacaaaggt caatacaaag gctcaggaga ctgaggctgc accctctcag    540

gccccagcag atgaacctga gcctgagagt gcagctgccc agtctcagga gaatcaggat    600

actcggccca aggtcaaagc caagaaagcc cgaaaggtga agcatctgga tggggaagag    660

gatggcagca gtgatcagag tcaggcttct ggaaccacag gtggccgaag ggtctcaaag    720

gccctaatgg cctcaatggc ccgcagggct tcaaggggtc ccatagcctt ttgggcccgc    780

agggcatcaa ggactcggtt ggctgcttgg gcccggagag ccttgctctc cctgagatca    840

cctaaagccc gtaggggcaa ggctcgccgt agagctgcca agctccagtc atcccaagag    900

cctgaagcac caccacctcg ggatgtggcc cttttgcaag ggagggcaaa tgatttggtg    960

aagtaccttt tggctaaaga ccagacgaag attcccatca agcgctcgga catgctgaag   1020

gacatcatca aagaatacac tgatgtgtac cccgaaatca ttgaacgagc aggctattcc   1080

ttggagaagg tatttgggat tcaattgaag gaaattgata agaatgacca cttgtacatt   1140

cttctcagca ccttagagcc cactgatgca ggcatactgg gaacgactaa ggactcaccc   1200

aagctgggtc tgctcatggt gcttcttagc atcatcttca tgaatggaaa tcggtccagt   1260

gaggctgtca tctgggaggt gctgcgcaag ttggggctgc gccctgggat acatcattca   1320

ctctttgggg acgtgaagaa gctcatcact gatgagtttg tgaagcagaa gtacctggac   1380

tatgccagag tccccaatag caatccccct gaatatgagt tcttctgggg cctgcgctct   1440

tactatgaga ccagcaagat gaaagtcctc aagtttgcct gcaaggtaca aaagaaggat   1500

cccaaggaat gggcagctca gtaccgagag gcgatggaag cggatttgaa ggctgcagct   1560

gaggctgcag ctgaagccaa ggctagggcc gagattagag ctcgaatggg cattgggctc   1620

ggctcggaga atgctgccgg gccctgcaac tgggacgaag ctgatatcgg accctgggcc   1680

aaagcccgga tccaggcggg agcagaagct aaagccaaag cccaagagag tggcagtgcc   1740

agcactggtg ccagtaccag taccaataac agtgccagtg ccagtgccag caccagtggt   1800

ggcttcagtg ctggtgccag cctgaccgcc actctcacat ttgggctctt cgctggcctt   1860

ggtggagctg gtgccagcac cagtggcagc tctggtgcct gtggtttctc ctacaagtga   1920

gattttagat attgttaatc ctgccagtct ttctcttcaa gccagggtgc atcctcagaa   1980

acctactcaa cacagcactc taggcagcca ctatcaatca attgaagttg acactctgca   2040

ttaaatctat ttgccatttc aaaaaaaaaa aaaaaaaaaa                         2080


<210>  819
<211>  3454
<212>  DNA
<213>  Human

<400>  819
gcccgctcgg ccgtggccgt gggagaggcg ccgggaggct gcgggcgcgg ggctccgggg     60

cgggggcggc gcgaacggcg cggacggcgc gggcgcgggg ggctgggtcc cggggcgctg    120

ctggggtgga cccccccgcc tcgaacttgg tacgcgccag cgagaggcca ggcccagccc    180

gggcggtaca atagggttgg gccgaggccg ggactgggcc ggcgccgggc ggggaacggg    240

ttcgcgaccg cagccgagag accccgggcg accggcacct ccgagactcg cgggccacct    300

gcctcgacct tccccggagc gcccccgcct ccgagtcgct acttgccggg ccgggccggg    360

ccgggcgtga tgcgccgcgg gacccctgtc ctggccactg gccgccgccg ccgccgccgc    420

tgagaccccg agacccccag tgacgccgca gccatggaga gcggcccgcg tgcggagctg    480

ggggcgggcg cacccccagc tgtggtcgcc aggacccccc cagagccaag accttctcca    540

gaaggtgacc cttccccccc accaccacca atgtcagccc tggtccccga cactcccccg    600

gacacccctc ctgccatgaa gaatgccact agctctaagc agctcccact ggaaccagag    660

agcccctcag ggcaggtcgg gcctaggcca gcccccccgc aggaagagtc cccttcctct    720

gaagcaaaga gcagaggacc caccccacca gccatgggcc cacgggatgc cagacctcct    780

cgaaggagca gccagccatc tccaacagca gtgccagcct ccgacagccc tcccaccaag    840

caagaggtga agaaggcagg agagagacac aagctggcaa aggagcggcg agaagagcgg    900

gccaagtacc tggcggccaa gaaggcagtg tggctggaga aggaggagaa ggccaaggcg    960

ctgcgggaga agcagctcca ggagcgccgg cgccggctgg aggagcaacg tcttaaagcc   1020

gagcaacgcc gtgcagccct ggaggaacgg cagcggcaga agctcgagaa aaacaaggag   1080

cgctatgaag cagccatcca acggtcagtg aagaagacgt gggccgaaat ccggcagcag   1140

cgctggtcct gggcaggggc cctgcaccac agctctccag gacataagac caatcgcagc   1200

ctgcagctga gcgcatggga gagcagcatc gtggatcgtc tgatgacgcc cactctctcc   1260

ttccttgctc ggagtcgcag cgcggtcaca ctgccccgca acggccggga ccagggtagg   1320

ggctgcgacc ctgggagagg ccccacgtgg ggccgggcag gggccagcct ggcgcgcggg   1380

ccgcaacccg accgcactca tccctctgca gccgtgccgg tgtgcccgcg ctcggcctcc   1440

gccagccccc tgacgccgtg cagcgtcacc cgaagcgtgc accgctgcgc ccccgccggt   1500

gagcgcgggg agcgccgcaa gcccaacgcc gggggcagcc ccgctccggt gcgccgccgg   1560

ccggaggcct cgccggtgca gaaaaaggag aagaaggaca aggagcggga aaacgagaag   1620

gagaagagtg ccctagcccg ggagcgcagc ctcaagaagc gccagtcgct gcccgcctcc   1680

ccacgtgccc gcctctccgc cagcaccgcc tctgagctca gccccaaatc caaggccagg   1740

ccatcctctc cctccacatc ctggcacagg cctgcctccc cctgccccag cccagggcca   1800

ggccacactc tgcctccaaa gccaccgtcc ccccgaggca ccactgcatc ccccaagggg   1860

cgggttcgga ggaaggagga ggcaaaggag agccccagcg ccgcagggcc cgaggacaag   1920

agccagagca agcgcagggc cagtaacgag aaggagtcag cagccccagc ctcaccggca   1980

ccttcgccgg cgccctcgcc caccccagcc ccgccccaga aggagcagcc ccccgcggag   2040

acccctacag acgctgctgt cttgacctca cccccagccc ctgctccccc ggtgacccct   2100

agcaaaccaa tggccggcac cacagaccga gaagaagcca ctcggctctt ggctgagaag   2160

cggcgccagg cccgggagca gcgggagcgc gaggagcagg agcggaggct gcaggcagaa   2220

agggacaagc gaatgcgaga ggagcagctg gcacgggagg ccgaggcccg ggcggagcgg   2280

gaggcggagg cccggaggcg ggaggagcag gaggcacgag agaaggcgca ggccgagcag   2340

gaggagcagg agcggctgca gaagcagaaa gaggaggccg aagctcggtc gcgggaagag   2400

gcggagcggc agcgtctgga gcgggaaaag cacttccagc agcaggagca agagcggcaa   2460

gagcgcagaa agcgtctgga ggagatcatg aagaggactc ggaagtcaga agtttctgaa   2520

accaagaagc aggacagcaa ggaggccaac gccaacggtt ccagcccaga gcctgtgaaa   2580

gctgtggagg ctcggtcccc agggctgcag aaggaggctg tgcagaaaga ggagcccatc   2640

ccacaggagc ctcagtggag tctcccaagc aaggagttgc cagcgtccct ggtgaatggc   2700

ctgcagcctc tcccagcaca ccaggagaat ggcttctcca ccaacggacc ctctggggac   2760

aagagtctga gccgaacacc agagacactc ctgccctttg cagaggcaga agccttcctc   2820

aagaaagctg tggtgcagtc cccgcaggtc acagaagtcc tttaagaggg tttgccttgg   2880

atccgggcac agttgtgagg gctcctctgc atcacctacc aggatgtctg gaggagaaaa   2940

agacagaaca aagatggaag tggcctgggc ccctgggggt gggtcctctc tgttgttttt   3000

aatctgcacc ttatagactg atgtctcttt ggccggagcc agatctgccc ctcagtgcat   3060

tcgtgtgctc gcacgcgcag acatcccttc tcccccatac acacatatac actcacagcc   3120

tctctggcct cttcccttgg ggaggggcca cctgtagtat ttgccttgat ttggtggggt   3180

acagtggatg tgaatactgt aaatagcttg tgctcagact cctctgcgtg gagagggtgg   3240

gtgcaggagg cagaccctcc ccccaaagcc ccctggggag atcttcctct ctctatttaa   3300

ctgtaactga gggggatccc aggtctgggg atgggggaca ccttgggcca caggatactg   3360

gttgcttcag gggtacccat gccccctgcc ctcgcctgga atcagtgtta ctgcatctga   3420

ttaaatgtct ccagaaataa agaataattc tgcc                               3454


<210>  820
<211>  4213
<212>  DNA
<213>  Human

<400>  820
ttcaccggaa aacacagtag ctgtagctgc acatagacgc ttcctctttc tgtttccccc     60

tcatccccct ccctagacct ctctgggctt tgacgtcatg tgtgctcctt tcggttgcca    120

tagcaacccc attccccaag ccctctgtcc gtctcctctg gtaggttcca caatggtaca    180

ggcagcatca cgctgcacaa tggtttccag gcagtgaaag agggtgattc agcaagccac    240

tcttcttcta ttttctttaa cctccccttc actttttatt tttatggggg tgggtggtgc    300

ttgctatatg cttacctttt tcttttcttt tttcattttt acaaatttcc ttttttgtcc    360

tcacccctca attcctaggg gcttgagtga gtttaagatt gggttttctt ggaaatcacc    420

tgtccatcgt taattttaaa caatctccat atctccaaag aatctcttcc atgttagtct    480

ggaatgtggt taatgaaaaa caagtaggga ggatttctgg ggcaaacact gccggatcag    540

gatcgtagtt ctcaggcacg gaatggctag tgtgagaaac accaacagca ggcccatctc    600

agatcttcac tatggcaact tatgcaagaa actgttgaat tagacccgtt tcctatagat    660

gagaaaccat acaagctgtg gtatttatga gcctccattt cttatactac tgcagtgaac    720

caacattgga tgtgaaaatt gccttttgtc aggtgtgtgt tccttacagg taaaacaagg    780

gattcgataa acaagtggat gtgtcatata ttgccaaaca ttacaacatg agcaaaagca    840

aagttgacaa ccagttctac agtgtggaag tgggagactc aaccttcaca gttctcaagc    900

gctaccagaa tctaaagcct attggctctg gggctcaggg catagtttgt gccgcgtatg    960

atgctgtcct tgacagaaat gtggccatta agaagctcag cagacccttt cagaaccaaa   1020

cacatgccaa gagagcgtac cgggagctgg tcctcatgaa gtgtgtgaac cataaaaaca   1080

ttattagttt attaaatgtc ttcacacccc agaaaacgct ggaggagttc caagatgttt   1140

acttagtaat ggaactgatg gatgccaact tatgtcaagt gattcagatg gaattagacc   1200

atgagcgaat gtcttacctg ctgtaccaaa tgttgtgtgg cattaagcac ctccattctg   1260

ctggaattat tcacagggat ttaaaaccaa gtaacattgt agtcaagtct gattgcacat   1320

tgaaaatcct ggactttgga ctggccagga cagcaggcac aagcttcatg atgactccat   1380

atgtggtgac acgttattac agagcccctg aggtcatcct ggggatgggc tacaaggaga   1440

acgtggatat atggtctgtg ggatgcatta tgggagaaat ggttcgccac aaaatcctct   1500

ttccaggaag ggactatatt gaccagtgga ataaggtaat tgaacaacta ggaacaccat   1560

gtccagaatt catgaagaaa ttgcaaccca cagtaagaaa ctatgtggag aatcggccca   1620

agtatgcggg actcaccttc cccaaactct tcccagattc cctcttccca gcggactccg   1680

agcacaataa actcaaagcc agccaagcca gggacttgtt gtcaaagatg ctagtgattg   1740

acccagcaaa aagaatatca gtggacgacg ccttacagca tccctacatc aacgtctggt   1800

atgacccagc cgaagtggag gcgcctccac ctcagatata tgacaagcag ttggatgaaa   1860

gagaacacac aattgaagaa tggaaagaac ttatctacaa ggaagtaatg aattcagaag   1920

aaaagactaa aaatggtgta gtaaaaggac agccttctcc ttcaggtgca gcagtgaaca   1980

gcagtgagag tctccctcca tcctcgtctg tcaatgacat ctcctccatg tccaccgacc   2040

agaccctggc atctgacact gacagcagcc tggaagcctc ggcaggaccc ctgggttgtt   2100

gcaggtgact agccgcctgc ctgcgaaacc cagcgttctt caggagatga tgtgatggaa   2160

cacacacaca cgcagacaca cacacacaca caaatgcaga cacacaacat caagaaaaca   2220

gcaagggaga gaatccaagc ctaaaattaa ataaatcttt cagcctgctt cttccccagg   2280

gttctgtatt gcagctaagc tcaaatgtat atttaacttc tagttgctct tgctttggtc   2340

ttcttccaat gatgcttact acagaaagca aatcagacac aattagagaa gccttttcca   2400

taaagtgtaa ttttaatggc tgcaaaaccg gcaacctgta actgcccttt taaatggcat   2460

gacaaggtgt gcagtggccc catccagcat gtgtgtgtct ctatcttgca tctacctgct   2520

ccttggccta gtcagatgga tgtagataca gatccgcatg tgtctgtatt catacagcac   2580

tacttactta gagatgctac tgtcagtgtc ctcagggctc taccaagaca taatgcactg   2640

gggtaccaca tggtccattt catgtgatct attactctga cataaaccca tctgtaatat   2700

attgccagta tataagctgt ttagtttgtt aattgattaa actgtatgtc ttataagaaa   2760

acatgtaaag ggggaatata tggggggagt gagctctctc agacccttga agatgtagct   2820

tccaaatttg aatggattaa atggcacctg tataccaatt tgtagaaaga acatatgtga   2880

tacttatgta aagtgtgggg cgagtgggta acagttttca ggcacaaaat ggtttggcct   2940

tctgaaggca ggtgtgaata aaagctgaga gtcttttctg tgacagtaaa gagtaggaga   3000

gactggaggg tagtgtgtgg tgtggactaa gactgaaagg aggttattac ccagatacta   3060

ggagacactg gtgtccctgt tttagagatt tggctctata cccatttgtc atttctcaat   3120

tactggtcac aacaagaggc cactggagaa agtggcaggt ggtgaagcaa ggttattgtg   3180

tgtgcttttg atgataagaa tctctctctg gaactgagca gaattgcctc catgtgaatt   3240

ccttcaacaa aaaaatgagc ctgcctagac tactttcaga ttgtggattg tgttttccat   3300

gtgtgggctg cttccctgat tcatactctg ccaaagtttt attttgagaa ataatattac   3360

tttcctcttc tgaaataaaa taataataat aataatgaaa cccccaaacc acagtgtgag   3420

tctcaggtta gcatttgaaa acatctccag agacattgtt attcctcagg agtttccctg   3480

actccttaat gtggctgatg tttcatgttt atttatttat tttaataagt atgagcaatc   3540

gaagggctga tcatctgagt tttgtactgc agtagatgta agagcaataa ctctgcccat   3600

aaatttactg ctgccaaata gttttagcaa tatgagtttg tcttaaaagc catgaagcat   3660

taatgtcaat gtttagcaaa atctccagaa tttagcttaa attaaattaa atgaaagtgc   3720

tttcctgagc acttaaggag gcactgtgaa acatcttggt tatgtacaag gcaataccaa   3780

ggtgatctca gcaataatca ggcttccctt cttattcact tcgaagtatc catcacagtt   3840

atttgcactc tgaccatgtt ggtgctcact agagtggtga tatttcacct gaagaagtga   3900

aagacaggaa gtggatggtt gatgagtgtg aactgattgg caaatagaat atccccaaaa   3960

cagagcaaac aagaatgcca gtgctctgaa aactgcctta aatataataa tagggaactt   4020

tctttctctc ttcaagcaat agagaccaca gggaactgca cccacctgca ccatcgccat   4080

gccagtggtg ctgccattct gagattattt cacacagtca gattcagtac acgcagtcat   4140

ttgtttaaaa taaatagaag aacattcctt tgtgcagctt gtcccctgga ataaaaatgg   4200

cccattttct cta                                                      4213


<210>  821
<211>  2640
<212>  DNA
<213>  Human

<400>  821
ctttacgtcg gcgcgtaacg agggggtgcg tgtgaggtca tcgcgcgggc gggcgggcgg     60

ggtctggcgg tttgaacgag acgaagacgg aaccggagcc ggttgcgggc agtggacgcg    120

gttctgccga gagccgaaga tggcagtgaa cgtatactca acgtcagtga ccagtgataa    180

cctaagtcga catgacatgc tggcctggat caatgagtct ctgcagttga atctgacaaa    240

gatcgaacag ttgtgctcag gggctgcgta ttgtcagttt atggacatgc tgttccctgg    300

ctccattgcc ttgaagaaag tgaaattcca agctaagcta gaacacgagt acatccagaa    360

cttcaaaata ctacaagcag gttttaagag aatgggtgtt gacaaaataa ttcctgtgga    420

caaattagta aaaggaaagt ttcaggacaa ttttgaattc gttcagtggt tcaagaagtt    480

tttcgatgca aactatgatg gaaaagacta tgaccctgtg gctgccagac aaggtcaaga    540

aactgcagtg gctccttccc ttgttgctcc agctctgaat aaaccgaaga aacctctcac    600

ttctagcagt gcagctcccc agaggcccat ctcaacacag agaaccgctg cggctcctaa    660

ggctggccct ggtgtggtgc gaaagaaccc tggtgtgggc aacggagacg acgaggcagc    720

tgagttgatg cagcaggtca acgtattgaa acttactgtt gaagacttgg agaaagagag    780

ggatttctac ttcggaaagc tacggaacat tgaattgatt tgccaggaga acgaggggga    840

aaacgaccct gtattgcaga ggattgtaga cattctgtat gccacagatg aaggctttgt    900

gatacctgat gaagggggcc cacaggagga gcaagaagag tattaacagc ctggaccagc    960

agagcaacat cggaattctt cactccaaat catgtgctta actgtaaaat actccctttt   1020

gttatcctta gaggactcac tggtttcttt tcataagcaa aaagtacctc ttcttaaagt   1080

gcactttgca gacgtttcac tccttttcca ataagtttga gttaggagct tttaccttgt   1140

agcagagcag tattaacacc tagttggttc acctggaaaa cagagaggct gaccgtgggg   1200

ctcaccatgc ggatgcgggt cacactgaat gctggagaga tgttatgtaa tatgctgagg   1260

tggcgacctc agtggagaaa tgtaaagact gaattgaatt ttaagctaat gtgaaatcag   1320

agaatgttgt aataagtaaa tgccttaaga gtatttaaaa tatgcttcca catttcaaaa   1380

tataaaatgt aacatgacaa gagattttgc gtttgacatt gtgtctggga aggaagggcc   1440

agaccttgga acctttggaa cctgctgtca acaggtctta cagggctgct tgaaccctca   1500

taggcctagg ctttggtcta aaaggaacat ttaaaaagtt gccctgtaaa gttatttggt   1560

gtcattgacc aattgcatcc cagctaaaaa gcaagaggca tcgttgcctg gataatagag   1620

gatgtgtttc agccctgaga tgttacagtt gaagagcttg gttttcattg agcatttctc   1680

tatttttcca gttatccccg aaatttctat gtattatatt ttttggggaa gtgaggtgtg   1740

cccagttttt taatctaaca actacttttg gggacttgcc cacatctctg ggatttgaat   1800

ggggattgta tcccatttta ctgtctttta ggtttacatt taccacgttt ctcttctctg   1860

ctccccttgc ccactgggga ctcctctttg gctccttgaa gtttgctgct tagagttgga   1920

agtgcagcag gcaggtgatc atgctgcaag ttctttctgg acctctggca aagggagtgg   1980

tcagtgaagg ccatcgttac cttgggatct gccaggctgg ggtgttttcg gtatctgctg   2040

ttcacagctc tccactgtaa tccgaatact ttgccagtgc actaatctct ttggagataa   2100

aattcattag tgtgttacta aatgttaatt ttcttttgcg gaaaatacag taccgtgtct   2160

gaattaatta ttaatattta aaatacttca ttccttaact ctccctcatt tgctttgccc   2220

acagcctatt cagttccttt gtttggcagg attctgcaaa atgtgtctca cccactactg   2280

agattgttca gcccctgatg tatttgtatt gatttgtttc tggtggtagc ttgtcctgaa   2340

atgtgtgtag aaagcaagta ttttatgata aaaatgttgt gtagtgcatg ctctgtgtgg   2400

aattcagagg aaaacccaga ttcagtgatt aacaatgcca aaaaatgcaa gtaactagcc   2460

attgttcaaa tgacagtggt gctatttctc ttttgtggcc ttttagactt ttgttgccct   2520

aaaattccat tttattggga acccattttc cacctggtct ttcttgacag ggtttttttc   2580

tactttaaac agtttctaaa taaaattctg tatttcaaga gtaaaaaaaa aaaaaaaaaa   2640


<210>  822
<211>  5544
<212>  DNA
<213>  Human

<400>  822
ggacggccga gcggcagggc gctcgcgcgc gcccactagt ggccggagga gaaggctccc     60

gcggaggccg cgctgcccgc cccctcccct ggggaggctc gcgttcccgc tgctcgcgcc    120

tgcgccgccc gccggcctca ggaacgcgcc ctcttcgccg gcgcgcgccc tcgcagtcac    180

cgccacccac cagctccggc accaacagca gcgccgctgc caccgcccac cttctgccgc    240

cgccaccaca gccaccttct cctcctccgc tgtcctctcc cgtcctcgcc tctgtcgact    300

atcaggtgaa ctttgaacca ggatggctga gccccgccag gagttcgaag tgatggaaga    360

tcacgctggg acgtacgggt tgggggacag gaaagatcag gggggctaca ccatgcacca    420

agaccaagag ggtgacacgg acgctggcct gaaagctgaa gaagcaggca ttggagacac    480

ccccagcctg gaagacgaag ctgctggtca cgtgacccaa gctcgcatgg tcagtaaaag    540

caaagacggg actggaagcg atgacaaaaa agccaagggg gctgatggta aaacgaagat    600

cgccacaccg cggggagcag cccctccagg ccagaagggc caggccaacg ccaccaggat    660

tccagcaaaa accccgcccg ctccaaagac accacccagc tctggtgaac ctccaaaatc    720

aggggatcgc agcggctaca gcagccccgg ctccccaggc actcccggca gccgctcccg    780

caccccgtcc cttccaaccc cacccacccg ggagcccaag aaggtggcag tggtccgtac    840

tccacccaag tcgccgtctt ccgccaagag ccgcctgcag acagcccccg tgcccatgcc    900

agacctgaag aatgtcaagt ccaagatcgg ctccactgag aacctgaagc accagccggg    960

aggcgggaag gtgcaaatag tctacaaacc agttgacctg agcaaggtga cctccaagtg   1020

tggctcatta ggcaacatcc atcataaacc aggaggtggc caggtggaag taaaatctga   1080

gaagcttgac ttcaaggaca gagtccagtc gaagattggg tccctggaca atatcaccca   1140

cgtccctggc ggaggaaata aaaagattga aacccacaag ctgaccttcc gcgagaacgc   1200

caaagccaag acagaccacg gggcggagat cgtgtacaag tcgccagtgg tgtctgggga   1260

cacgtctcca cggcatctca gcaatgtctc ctccaccggc agcatcgaca tggtagactc   1320

gccccagctc gccacgctag ctgacgaggt gtctgcctcc ctggccaagc agggtttgtg   1380

atcaggcccc tggggcggtc aataattgtg gagaggagag aatgagagag tgtggaaaaa   1440

aaaagaataa tgacccggcc cccgccctct gcccccagct gctcctcgca gttcggttaa   1500

ttggttaatc acttaacctg cttttgtcac tcggctttgg ctcgggactt caaaatcagt   1560

gatgggagta agagcaaatt tcatctttcc aaattgatgg gtgggctagt aataaaatat   1620

ttaaaaaaaa acattcaaaa acatggccac atccaacatt tcctcaggca attccttttg   1680

attctttttt cttccccctc catgtagaag agggagaagg agaggctctg aaagctgctt   1740

ctgggggatt tcaagggact gggggtgcca accacctctg gccctgttgt gggggtgtca   1800

cagaggcagt ggcagcaaca aaggatttga aacttggtgt gttcgtggag ccacaggcag   1860

acgatgtcaa ccttgtgtga gtgtgacggg ggttggggtg gggcgggagg ccacggggga   1920

ggccgaggca ggggctgggc agaggggaga ggaagcacaa gaagtgggag tgggagagga   1980

agccacgtgc tggagagtag acatccccct ccttgccgct gggagagcca aggcctatgc   2040

cacctgcagc gtctgagcgg ccgcctgtcc ttggtggccg ggggtggggg cctgctgtgg   2100

gtcagtgtgc caccctctgc agggcagcct gtgggagaag ggacagcggg taaaaagaga   2160

aggcaagctg gcaggagggt ggcacttcgt ggatgacctc cttagaaaag actgaccttg   2220

atgtcttgag agcgctggcc tcttcctccc tccctgcagg gtagggggcc tgagttgagg   2280

ggcttccctc tgctccacag aaaccctgtt ttattgagtt ctgaaggttg gaactgctgc   2340

catgattttg gccactttgc agacctggga ctttagggct aaccagttct ctttgtaagg   2400

acttgtgcct cttgggagac gtccacccgt ttccaagcct gggccactgg catctctgga   2460

gtgtgtgggg gtctgggagg caggtcccga gccccctgtc cttcccacgg ccactgcagt   2520

caccccgtct gcgccgctgt gctgttgtct gccgtgagag cccaatcact gcctataccc   2580

ctcatcacac gtcacaatgt cccgaattcc cagcctcacc accccttctc agtaatgacc   2640

ctggttggtt gcaggaggta cctactccat actgagggtg aaattaaggg aaggcaaagt   2700

ccaggcacaa gagtgggacc ccagcctctc actctcagtt ccactcatcc aactgggacc   2760

ctcaccacga atctcatgat ctgattcggt tccctgtctc ctcctcccgt cacagatgtg   2820

agccagggca ctgctcagct gtgaccctag gtgtttctgc cttgttgaca tggagagagc   2880

cctttcccct gagaaggcct ggccccttcc tgtgctgagc ccacagcagc aggctgggtg   2940

tcttggttgt cagtggtggc accaggatgg aagggcaagg cacccagggc aggcccacag   3000

tcccgctgtc ccccacttgc accctagctt gtagctgcca acctcccaga cagcccagcc   3060

cgctgctcag ctccacatgc atagtatcag ccctccacac ccgacaaagg ggaacacacc   3120

cccttggaaa tggttctttt cccccagtcc cagctggaag ccatgctgtc tgttctgctg   3180

gagcagctga acatatacat agatgttgcc ctgccctccc catctgcacc ctgttgagtt   3240

gtagttggat ttgtctgttt atgcttggat tcaccagagt gactatgata gtgaaaagaa   3300

aaaaaaaaaa aaaaaaggac gcatgtatct tgaaatgctt gtaaagaggt ttctaaccca   3360

ccctcacgag gtgtctctca cccccacact gggactcgtg tggcctgtgt ggtgccaccc   3420

tgctggggcc tcccaagttt tgaaaggctt tcctcagcac ctgggaccca acagagacca   3480

gcttctagca gctaaggagg ccgttcagct gtgacgaagg cctgaagcac aggattagga   3540

ctgaagcgat gatgtcccct tccctacttc cccttggggc tccctgtgtc agggcacaga   3600

ctaggtcttg tggctggtct ggcttgcggc gcgaggatgg ttctctctgg tcatagcccg   3660

aagtctcatg gcagtcccaa aggaggctta caactcctgc atcacaagaa aaaggaagcc   3720

actgccagct ggggggatct gcagctccca gaagctccgt gagcctcagc cacccctcag   3780

actgggttcc tctccaagct cgccctctgg aggggcagcg cagcctccca ccaagggccc   3840

tgcgaccaca gcagggattg ggatgaattg cctgtcctgg atctgctcta gaggcccaag   3900

ctgcctgcct gaggaaggat gacttgacaa gtcaggagac actgttccca aagccttgac   3960

cagagcacct cagcccgctg accttgcaca aactccatct gctgccatga gaaaagggaa   4020

gccgcctttg caaaacattg ctgcctaaag aaactcagca gcctcaggcc caattctgcc   4080

acttctggtt tgggtacagt taaaggcaac cctgagggac ttggcagtag aaatccaggg   4140

cctcccctgg ggctggcagc ttcgtgtgca gctagagctt tacctgaaag gaagtctctg   4200

ggcccagaac tctccaccaa gagcctccct gccgttcgct gagtcccagc aattctccta   4260

agttgaaggg atctgagaag gagaaggaaa tgtggggtag atttggtggt ggttagagat   4320

atgcccccct cattactgcc aacagtttcg gctgcatttc ttcacgcacc tcggttcctc   4380

ttcctgaagt tcttgtgccc tgctcttcag caccatgggc cttcttatac ggaaggctct   4440

gggatctccc ccttgtgggg caggctcttg gggccagcct aagatcatgg tttagggtga   4500

tcagtgctgg cagataaatt gaaaaggcac gctggcttgt gatcttaaat gaggacaatc   4560

cccccagggc tgggcactcc tcccctcccc tcacttctcc cacctgcaga gccagtgtcc   4620

ttgggtgggc tagataggat atactgtatg ccggctcctt caagctgctg actcacttta   4680

tcaatagttc catttaaatt gacttcagtg gtgagactgt atcctgtttg ctattgcttg   4740

ttgtgctatg gggggagggg ggaggaatgt gtaagatagt taacatgggc aaagggagat   4800

cttggggtgc agcacttaaa ctgcctcgta acccttttca tgatttcaac cacatttgct   4860

agagggaggg agcagccacg gagttagagg cccttggggt ttctcttttc cactgacagg   4920

ctttcccagg cagctggcta gttcattccc tccccagcca ggtgcaggcg taggaatatg   4980

gacatctggt tgctttggcc tgctgccctc tttcaggggt cctaagccca caatcatgcc   5040

tccctaagac cttggcatcc ttccctctaa gccgttggca cctctgtgcc acctctcaca   5100

ctggctccag acacacagcc tgtgcttttg gagctgagat cactcgcttc accctcctca   5160

tctttgttct ccaagtaaag ccacgaggtc ggggcgaggg cagaggtgat cacctgcgtg   5220

tcccatctac agacctgcag cttcataaaa cttctgattt ctcttcagct ttgaaaaggg   5280

ttaccctggg cactggccta gagcctcacc tcctaataga cttagcccca tgagtttgcc   5340

atgttgagca ggactatttc tggcacttgc aagtcccatg atttcttcgg taattctgag   5400

ggtgggggga gggacatgaa atcatcttag cttagctttc tgtctgtgaa tgtctatata   5460

gtgtattgtg tgttttaaca aatgatttac actgactgtt gctgtaaaag tgaatttgga   5520

aataaagtta ttactctgat taaa                                          5544


<210>  823
<211>  5756
<212>  DNA
<213>  Human

<400>  823
taggcaggcg gctgagccgg cggcgggtgg cctgcccaac gtgtgctggg tgggagaagg     60

cgaggcgtca gcgatgctgt ctcttccgtg aggagcgcag aggaggtcgc ggcgccggag    120

gccccagaag gctcgaaggc gccgcgggct ggggtcggtg gcttagggag cccgtccggc    180

catggtggcc gcgggtggtg gttggcgcgg ctgcgctgcg gcccggggca gtgcggagcc    240

gggacagtcg cggcgctgac gcccgcgggc cccagctgca gatatgaagc ggagccgctg    300

ccgcgaccga ccgcagccgc cgccgcccga ccgccgggag gatggagttc agcgggcagc    360

ggagctgtct cagtctttgc cgccgcgccg gcgagcgccg cccgggaggc agcggctgga    420

ggagcggacg ggccccgcgg ggcccgaggg caaggagcag gatgtagtaa ctggagttag    480

tcccctgctc ttcaggaaac tcagtaatcc tgacatattt tcatccactg gaaaagttaa    540

acttcagcga caactgagtc aggatgattg taagttatgg agaggaaacc tggccagctc    600

tctatcgggt aagcagctgc tccctttgtc cagcagtgta catagcagtg tgggacaggt    660

gacttggcag tcgtcaggag aagcatcaaa cctggttcga atgagaaacc agtcccttgg    720

acagtctgca ccttctctta ctgctggcct gaaggagttg agccttccaa gaagaggcag    780

cttttgtcgg acaagtaacc gcaagagctt gattgtgacc tctagcacat cacctacact    840

accacggcca cactcaccac tccatggcca cacaggtaac agtcctttgg acagcccccg    900

gaatttctct ccaaatgcac ctgctcactt ttcttttgtt cctgcccgta ggactgatgg    960

gcggcgctgg tctttggcct ctttgccctc ttcaggatat ggaactaaca ctcctagctc   1020

cactgtctca tcatcatgct cctcacagga aaagctgcat cagttgcctt tccagcctac   1080

agctgatgag ctgcactttt tgacgaagca tttcagcaca gagagcgtac cagatgagga   1140

aggacggcag tccccagcca tgcggcctcg ctcccggagc ctcagtcccg gacgatcccc   1200

agtatccttt gacagtgaaa taataatgat gaatcatgtt tacaaagaaa gattcccaaa   1260

ggccaccgca caaatggaag agcgactagc agagtttatt tcctccaaca ctccagacag   1320

cgtgctgccc ttggcagatg gagccctgag ctttattcat catcaggtga ttgagatggc   1380

ccgagactgc ctggataaat ctcggagtgg cctcattaca tcacaatact tctacgaact   1440

tcaagataat ttggagaaac ttttacaaga tgctcatgag cgctcagaga gctcagaagt   1500

ggcttttgtg atgcagctgg tgaaaaagct gatgattatc attgcccgcc cagcacgtct   1560

cctggaatgc ctggagtttg accctgaaga gttctaccac cttttagaag cagctgaggg   1620

ccacgccaaa gagggacaag ggattaaatg tgacattccc cgctacatcg ttagccagct   1680

gggcctcacc cgggatcccc tagaagaaat ggcccagttg agcagctgtg acagtcctga   1740

cactccagag acagatgatt ctattgaggg ccatggggca tctctgccat ctaaaaagac   1800

accctctgaa gaggacttcg agaccattaa gctcatcagc aatggcgcct atggggctgt   1860

atttctggtg cggcacaagt ccacccggca gcgctttgcc atgaagaaga tcaacaagca   1920

gaacctgatc ctacggaacc agatccagca ggccttcgtg gagcgtgaca tactgacttt   1980

cgctgagaac ccctttgtgg tcagcatgtt ctgctccttt gataccaagc gccacttgtg   2040

catggtgatg gagtacgttg aagggggaga ctgtgccact ctgctgaaga atattggggc   2100

cctgcctgtg gacatggtgc gtctatactt tgcggaaact gtgctggccc tggagtactt   2160

acacaactat ggcatcgtgc accgtgacct caagcctgac aacctcctaa ttacatccat   2220

ggggcacatc aagctcacgg actttggact gtccaaaatt ggcctcatga gtctgacaac   2280

gaacttgtat gagggtcata ttgaaaagga tgcccgggaa ttcctggaca agcaggtatg   2340

cgggacccca gaatacattg cgcctgaggt gatcctgcgc cagggctatg ggaagccagt   2400

ggactggtgg gccatgggca ttatcctgta tgagttcctg gtgggctgcg tccctttttt   2460

tggagatact ccggaggagc tctttgggca ggtgatcagt gatgagattg tgtggcctga   2520

gggtgatgag gcactgcccc cagacgccca ggacctcacc tccaaactgc tccaccagaa   2580

ccctctggag agacttggca caggcagtgc ctatgaggtg aagcagcacc cattctttac   2640

tggtctggac tggacaggac ttctccgcca gaaggctgaa tttattcctc agttggagtc   2700

agaggatgat actagctatt ttgacacccg ctcagagcga taccaccaca tggactcgga   2760

ggatgaggaa gaagtgagtg aggatggctg ccttgagatc cgccagttct cttcctgctc   2820

tccaaggttc aacaaggtgt acagcagcat ggagcggctc tcactgctcg aggagcgccg   2880

gacaccaccc ccgaccaagc gcagcctgag tgaggagaag gaggaccatt cagatggcct   2940

ggcagggctc aaaggccgag accggagctg ggtgattggc tcccctgaga tattacggaa   3000

gcggctgtcg gtgtctgagt catcccacac agagagtgac tcaagccctc caatgacagt   3060

gcgacgccgc tgctcaggcc tcctggatgc gcctcggttc ccggagggcc ctgaggaggc   3120

cagcagcacc ctcaggaggc aaccacagga gggtatatgg gtcctgacac ccccatctgg   3180

agagggggta tctgggcctg tcactgaaca ctcaggggag cagcggccaa agctggatga   3240

ggaagctgtt ggccggagca gtggttccag tccagctatg gagacccgag gccgtgggac   3300

ctcacagctg gctgagggag ccacagccaa ggccatcagt gacctggctg tgcgtagggc   3360

ccgccaccgg ctgctctctg gggactcaac agagaagcgc actgctcgcc ctgtcaacaa   3420

agtgatcaag tccgcctcag ccacagccct ctcactcctc attccttcgg aacaccacac   3480

ctgctccccg ttggccagcc ccatgtcccc acattctcag tcgtccaacc catcatcccg   3540

ggactcttct ccaagcaggg acttcttgcc agcccttggc agcatgaggc ctcccatcat   3600

catccaccga gctggcaaga agtatggctt caccctgcgg gccattcgcg tctacatggg   3660

tgactccgat gtctacaccg tgcaccatat ggtgtggcac gtggaggatg gaggtccggc   3720

cagtgaggca gggcttcgtc aaggtgacct catcacccat gtcaatgggg aacctgtgca   3780

tggcctggtg cacacggagg tggtagagct gatcctgaag agtggaaaca aggtggccat   3840

ttcaacaact cccctggaga acacatccat taaagtgggg ccagctcgga agggcagcta   3900

caaggccaag atggcccgaa ggagcaagag gagccgcggc aaggatgggc aagaaagcag   3960

aaaaaggagc tccctgttcc gcaagatcac caagcaagca tccctgctcc acaccagccg   4020

cagcctttct tcccttaacc gctccttgtc atcaggggag agtgggccag gctctcccac   4080

acacagccac agcctttccc cccgatctcc cactcaaggc taccgggtga cccccgatgc   4140

tgtgcattca gtgggaggga attcatcaca gagcagctcc cccagctcca gcgtgcccag   4200

ttccccagcc ggctctgggc acacacggcc cagctccctc cacggtctgg cacccaagct   4260

ccaacgccag taccgctctc cacggcgcaa gtcagcaggc agcatcccac tgtcaccact   4320

ggcccacacc ccttctcccc cacccccaac agcttcacct cagcggtccc catcgcccct   4380

gtctggccat gtagcccagg cctttcccac aaagcttcac ttgtcacctc ccctgggcag   4440

gcaactctca cggcccaaga gtgcggagcc accccgttca ccactactca agagggtgca   4500

gtcggctgag aaactggcag cagcacttgc cgcctctgag aagaagctag ccacttctcg   4560

caagcacagc cttgacctgc cccactctga actaaagaag gaactgccgc ccagggaagt   4620

gagccctctg gaggtagttg gagccaggag tgtgctgtct ggcaaggggg ccctgccagg   4680

gaagggggtg ctgcagcctg ctccctcacg ggccctaggc accctccggc aggaccgagc   4740

cgaacgacgg gagtcgctgc agaagcaaga agccattcgt gaggtggact cctcagagga   4800

cgacaccgag gaagggcctg agaacagcca gggtgcacag gagctgagct tggcacctca   4860

cccagaagtg agccagagtg tggcccctaa aggagcagga gagagtgggg aagaggatcc   4920

tttcccgtcc agagacccta ggagcctggg cccaatggtc ccaagcctat tgacagggat   4980

cacactgggg cctcccagaa tggaaagtcc cagtggtccc cacaggaggc tcgggagccc   5040

acaagccatt gaggaggctg ccagctcctc ctcagcaggc cccaacctag gtcagtctgg   5100

agccacagac cccatccctc ctgaaggttg ctggaaggcc cagcacctcc acacccaggc   5160

actaacagca ctttctccca gcacttcggg actcaccccc accagcagtt gctctcctcc   5220

cagctccacc tctgggaagc tgagcatgtg gtcctggaaa tcccttattg agggcccaga   5280

cagggcatcc ccaagcagaa aggcaaccat ggcaggtggg ctagccaacc tccaggattt   5340

ggaaaacaca actccagccc agcctaagaa cctgtctccc agggagcagg ggaagacaca   5400

gccacctagt gcccccagac tggcccatcc atcttatgag gatcccagcc agggctggct   5460

atgggagtct gagtgtgcac aagcagtgaa agaggatcca gccctgagca tcacccaagt   5520

gcctgatgcc tcaggtgaca gaaggcagga cgttccatgc cgaggctgcc ccctcaccca   5580

gaagtctgag cccagcctca ggaggggcca agaaccaggg ggccatcaaa agcatcggga   5640

tttggcattg gttccagatg agcttttaaa gcaaacatag cagttgtttg ccatttcttg   5700

cactcagacc tgtgtaatat atgctcctgg aaaccatcaa aaaaaaaaaa aaaaaa       5756


<210>  824
<211>  2559
<212>  DNA
<213>  Human

<400>  824
gcgggccgag gagccgggcg caatggagcg gaagaggtgg gagtgcccgg cgctcccgca     60

gggctgggag agggaagaag tgcccagaag gtcggggctg tcggccggcc acagggatgt    120

cttttactat agcccgagcg ggaagaagtt ccgcagcaag ccgcagctgg cgcgctacct    180

gggcggctcc atggacctga gcaccttcga cttccgcacg ggcaagatgc tgatgagcaa    240

gatgaacaag agccgccagc gcgtgcgcta cgactcctcc aaccaggtca agggcaagcc    300

cgacctgaac acggcgctgc ccgtgcgcca gacggcgtcc atcttcaagc agccggtgac    360

caagattacc aaccacccca gcaacaaggt caagagcgac ccgcagaagg cggtggacca    420

gccgcgccag ctcttctggg agaagaagct gagcggcctg aacgccttcg acattgctga    480

ggagctggtc aagaccatgg acctccccaa gggcctgcag ggggtgggac ctggctgcac    540

ggatgagacg ctgctgtcgg ccatcgccag cgccctgcac actagcacca tgcccatcac    600

gggacagctc tcggccgccg tggagaagaa ccccggcgta tggctcaaca ccacgcagcc    660

cctgtgcaaa gccttcatgg tgaccgacga ggacatcagg aagcaggaag agctggtgca    720

gcaggtgcgg aagcggctgg aggaggcgct gatggccgac atgctggcgc acgtggagga    780

gctggcccgt gacggggagg cgccgctgga caaggcctgc gctgaggacg acgacgagga    840

agacgaggag gaggaggagg aggagcccga cccggacccg gagatggagc acgtctaggg    900

caggtgctgc ggggccacgg gggctccctg gagtcgggtc ctggcagtgg ggactgcctg    960

gtgaacacag atgtgcttgg gatgacgggt gcctcccaag agcttcccat ctccctagaa   1020

gagcccaagc gtccccgtcc cgtggagtcg ctaaagccag ccctccctgt cctttccaga   1080

ggccctgccg agagcccgtg ctgcctgctg gagccgcctg cagacgcggt cctcggcccc   1140

acgtgaacca ggctcggcgg cgaagcccag ccttggagac acccaggagg aaggccgtgc   1200

tcctggctcc ctcctcggcc cgtccccact tcccggggcc tcggggcaca cagctggggc   1260

tgcccccacc cgaaagaccc tccacgctcg tcctctacag agtccggctt cgggaagtgc   1320

cgggtgctcc tgggccctgc ctggctccct acgacctttg ggctcgaggc cagctcctcc   1380

ccatgcccgc tgtcccagct ccttgagact ggagagcagc cagcaggtgc ccggcagctc   1440

ggcgccacgg cttgctgaca gctgggaggg tttctcggtc tggaggcgta gttttgaaac   1500

tcacatcacc cactgtgcag cgtgaggacg ggactctggt ctgctgtggg gggcatgcag   1560

gacggcgcca ctctctgccc tgccatgcgg ctggtggtgc cacagagcct caccgtgcct   1620

gagtggcatg cccaggaggc cgctctcctt cagtaaatgt aacacagtcg aggcacgtca   1680

tcgggcagcc ttccctgtgt gccaacgcca gccttcgctt ctgaaaacca aactccagcc   1740

gctgccagtc gggacttggt cgcccggcgc tgccagaatg ctccactgcc agccggcccc   1800

cctgcctcgg tttcccttct gtttagtggc gacacaggca cccagctttg gggtggtgct   1860

gacgctccca ggggtgccag gagccactgg gacagggtga ggctcccaga cgctcctcga   1920

ggtgcccagc tctccaggga gcttctggcc caaggccgtc tgagggatct gctccttaac   1980

cccccagtgc cttggcgagg gcaggttcca agccacagac gcctgccccg agtggactct   2040

gcggccagtc cctggtgccc tcctggccct gctgcccagt gagggctcct acgggtgggt   2100

tcattggcct gggcccagcg agcccccacc tgcattgacc ttaggcccat agagagggcc   2160

tgtcccggtg ctgccccagc caggatctgg tcgctgcccc agggggactg atgggcagag   2220

tcgcccctgt ggctggactg tgaccatccc tgatggggcc tgaccgcggg agctgaggaa   2280

gcgccgctcc accgtctgcc ctccaaggac ccgcatggag gcagtgggct ggcagcttcc   2340

tgctgctccc tgtcagagtc aaagcacaaa tcctcaggac gggctcaagg gccagggcag   2400

ccgagggaag ctccaggtgg ggaccacgtc ttcctgaggt tggtgcccac tggctgggac   2460

cctttgcagt ggggtggcct cccctctgtc tgcctggtgg agggagccgt gggcgtgggg   2520

acgtgactga ataaagccac catgggtgga tgtgcttgg                          2559


<210>  825
<211>  2551
<212>  DNA
<213>  Human

<400>  825
atcagcccaa aggtaggctc aggctccgac ggtggccggc gggggtcacg aggcttcgta     60

gtggaggaac gggtttggcg tgtgggacgc agctgcctct gtactgggga gtcacggagt    120

ggccgggctc cagggacatg gcggcggcct ctgcggtgtc ggtgctgctg gtggcggcgg    180

agaggaaccg gtggcatcgt ctcccgagcc tgctcctgcc gccgaggaca tgggtgtgga    240

ggcaaagaac catgaagtac acaacagcca caggaagaaa cattaccaag gtcctcattg    300

caaacagagg agaaattgcc tgcagggtga tgcgcacagc caaaaaactg ggtgtacaga    360

ctgtggcggt ttatagtgag gctgacagaa attccatgca tgtagatatg gcagatgaag    420

catattccat cggccccgct ccctcccagc agagctacct atctatggag aaaatcattc    480

aagtggccaa gacctctgct gcacaggcta tccatccagg atgcggtttt ctctcagaaa    540

acatggaatt tgctgaactt tgtaagcaag aaggaattat ttttataggc cctcctccat    600

ctgcaattag agacatgggt ataaagagca catccaaatc cataatggct gctgctggag    660

tacctgttgt ggagggttat catggtgagg accaatcaga ccagtgcctg aaggaacacg    720

ccaggagaat tggctatcct gtcatgatta aagccgtccg gggtggagga ggaaaaggaa    780

tgaggattgt tagatcagaa caagaatttc aagaacagtt agagtcagca cggagagaag    840

ctaagaagtc tttcaatgat gatgctatgc tgatcgagaa gtttgtagac acaccgaggc    900

atgtagaagt ccaggtgttt ggtgatcacc atggcaatgc tgtgtacttg tttgaaagag    960

actgtagtgt gcagaggcga catcagaaga tcattgagga ggccccagcg cctggtatta   1020

aatctgaagt aagaaaaaag ctgggagaag ctgcagtcag agctgctaaa gctgtaaatt   1080

atgttggagc agggactgtg gagtttatta tggactcaaa acataatttc tgtttcatgg   1140

agatgaatac aaggctgcaa gtggaacatc ctgttactga gatgatcaca ggaactgact   1200

tggtggagtg gcagcttaga attgcagcag gagagaagat tcctttgagc caggaagaaa   1260

taactctgca gggccatgcc ttcgaagcta gaatatatgc agaagatcct agcaataact   1320

tcatgcctgt ggcaggccca ttagtgcacc tctctactcc tcgagcagac ccttccacca   1380

ggattgaaac tggagtacgg caaggagacg aagtttccgt gcattatgac cccatgattg   1440

cgaagctggt cgtgtgggca gcagatcgcc aggcggcatt gacaaaactg aggtacagcc   1500

ttcgtcagta caatattgtt ggactgcaca ccaacattga cttcttactc aacctgtctg   1560

gccacccaga gtttgaagct gggaacgtgc acactgattt catccctcaa caccacaaac   1620

agttgttgct cagtcggaag gctgcagcca aagagtcttt atgccaggca gccctgggtc   1680

tcatcctcaa ggagaaagcc atgaccgaca ctttcactct tcaggcacat gatcaattct   1740

ctccattttc gtctagcagt ggaagaagac tgaatatctc gtataccaga aacatgactc   1800

ttaaagatgg taaaaacaat gtagccatag ctgtaacgta taaccatgat gggtcttata   1860

gcatgcagat tgaagataaa actttccaag tccttggtaa tctttacagc gagggagact   1920

gcacttacct gaaatgttct gttaatggag ttgctagtaa agcgaagctg attatcctgg   1980

aaaacactat ttacctattt tccaaggaag gaagtattga gattgacatt ccagtcccca   2040

aatacttatc ttctgtgagc tcacaagaaa ctcagggcgg ccccttagct cctatgactg   2100

gaaccattga aaaggtgttt gtcaaagctg gagacaaagt gaaagcggga gattccctca   2160

tggttatgat cgccatgaag atggagcata ccataaagtc tccaaaggat ggcacagtaa   2220

agaaagtgtt ctacagagaa ggtgctcagg ccaacagaca cactccttta gtcgagtttg   2280

aggaggaaga atcagacaaa agggaatcgg aataaactcc agcaaggaaa tggccagtta   2340

agtagtgtct tctctctcca ccaaaaagag gaagtgcctc cagcttttct gggggtctca   2400

taaagagcag ttttactaaa tgattgtatg cttatgctga acacctttca tattggagaa   2460

tcatgcattt gggtcactaa ttatctcaaa atatttcata ctaataaagt tgaattattt   2520

tttattggaa gccaaaaaaa aaaaaaaaaa a                                  2551


<210>  826
<211>  7450
<212>  DNA
<213>  Human

<400>  826
cgccggggcg agttcctgca gggtggaccc ggcgatcagg tctccgcggt gccactttgg     60

gcgcgggcgg gaagccggga cgctccgcac ctgcagcgac cttgggctcc gcggagcggg    120

cgcgggcacc tgtggctgcg tcctatggcg cacgtggagg cggaggctcc ggggagccgc    180

cggggccgcc tgtgagccgg agagcggagg aggcaccggc gcgcacgatg tcgttccttg    240

aagaggcgag ggcagcgggg cgcgcggtgg tcctggcgtt ggtgctgctg ctgctccccg    300

ccgtgcccgt gggcgccagc gttccgccgc ggcccctgct cccgctgcag cccggcatgc    360

cccacgtgtg tgctgagcag gagctgaccc tggtgggccg ccgccagccg tgcgtgcagg    420

ccttaagcca cacggtgccg gtgtggaagg ccggctgtgg gtggcaggcg tggtgcgtgg    480

gtcatgagcg gagaaccgtc tactacatgg gctacaggca ggtgtatacc acggaggccc    540

ggaccgtgct caggtgctgc cgagggtgga tgcagcagcc cgacgaggag ggctgcctct    600

cggctgaatg cagcgccagc ctctgttttc acggtggccg ttgtgtgcca ggctcagccc    660

agccgtgtca ctgtcccccc ggcttccagg gaccccgctg tcagtatgat gtggacgaat    720

gccgaaccca caacggtggc tgccagcacc ggtgcgtgaa caccccaggc tcctacctct    780

gtgagtgcaa gcccggcttc cggctccaca ctgacagcag gacctgcctg gccattaact    840

cctgcgccct gggcaatggc ggctgccagc accactgtgt ccagctcaca atcactcggc    900

atcgctgcca gtgccggccc gggttccagc tccaggagga cggcaggcat tgtgtccgta    960

gaagcccgtg tgccaacagg aacggcagct gcatgcacag gtgccaggtg gtccggggcc   1020

tcgcccgctg tgagtgccac gtgggctatc agctagcagc ggacggcaag gcctgtgaag   1080

atgtggacga atgtgccgca gggctggccc agtgtgccca tggctgcctc aacacccagg   1140

ggtccttcaa gtgcgtgtgt cacgcgggct atgagctggg cgccgatggc cggcagtgct   1200

accggattga gatggaaatc gtgaacagct gtgaggccaa caacggcggc tgctcccatg   1260

gctgcagcca caccagtgct gggcccctgt gcacatgtcc ccgcggctac gagctggaca   1320

cagatcagag gacctgcatc gatgtcgacg actgtgcaga cagcccgtgc tgccagcagg   1380

tgtgcaccaa caaccctggc gggtacgagt gcggctgcta cgccggctac cggctcagtg   1440

ccgatggctg cggctgtgag gatgtggatg agtgcgcctc cagccgtggc ggctgcgagc   1500

accactgcac caacctggcc ggctccttcc agtgctcctg cgaggccggc taccggctgc   1560

acgaggaccg taggggctgc agccccctgg aggagccgat ggtggacctg gacggcgagc   1620

tgcctttcgt gcggcccctg ccccacattg ccgtgctcca ggacgagctg ccgcaactct   1680

tccaggatga cgacgtcggg gccgatgagg aagaggcaga gttgcggggc gaacacacgc   1740

tcacagagaa gtttgtctgc ctggatgact cctttggcca tgactgcagc ttgacctgtg   1800

atgactgcag gaacggaggg acctgcctcc tgggcctgga tggctgtgat tgccccgagg   1860

gctggactgg gctcatctgc aatgagactt gtcctccgga cacctttggg aagaactgca   1920

gcttctcctg cagctgtcag aatggtggga cctgcgactc tgtcacgggg gcctgccgct   1980

gccccccggg tgtcagtgga actaactgtg aggatggctg ccccaagggc tactatggca   2040

agcactgtcg caagaaatgc aactgtgcca accggggccg gtgccaccgc ctctacgggg   2100

cctgcctctg cgacccaggg ctctacggcc gcttctgcca cctcacctgc ccgccgtggg   2160

cctttgggcc gggctgctcg gaggagtgcc agtgtgtgca gccccacacg cagtcctgtg   2220

acaagaggga tggcagctgc tcctgcaagg ctggcttccg gggcgagcgc tgtcaggcag   2280

agtgtgagct gggctacttt gggccggggt gctggcaggc atgcacctgc ccagtgggcg   2340

tggcctgtga ctccgtgagc ggcgagtgtg ggaagcggtg tcctgctggc ttccagggag   2400

aggactgtgg ccaagagtgc ccggtgggga cgtttggcgt gaactgctcg agctcctgct   2460

cctgtggggg ggccccctgc cacggggtca cggggcagtg ccggtgtccg ccggggagga   2520

ctggggaaga ctgtgaggca gattgtcccg agggccgctg ggggctgggc tgccaggaga   2580

tctgcccagc atgccagcac gctgcccgct gcgaccctga gaccggagcc tgcctgtgcc   2640

tccctggctt cgtcggcagc cgctgccagg acgtgtgccc agcaggctgg tatggtccca   2700

gctgccagac aaggtgctct tgtgccaatg atgggcactg ccacccagcc accggacact   2760

gcagctgtgc ccccgggtgg accggcttta gctgccagag agcctgtgat actgggcact   2820

ggggacctga ctgcagccac ccctgcaact gcagcgctgg ccacgggagc tgtgatgcca   2880

tcagcggcct gtgtctgtgt gaggctggct acgtgggccc gcggtgcgag cagcagtgtc   2940

cccagggcca ctttgggccc ggctgtgagc agcggtgcca gtgtcagcat ggagcagcct   3000

gtgaccacgt cagcggggcc tgcacctgcc cggccggctg gaggggcacc ttctgcgagc   3060

atgcctgccc ggccggcttc tttggattgg actgtcgcag tgcctgcaac tgcaccgccg   3120

gagctgcctg tgatgccgtg aatggctcct gcctctgccc cgctggccgc cggggccccc   3180

gctgtgccga gacctgccca gcccacacct acgggcacaa ttgcagccag gcctgtgcct   3240

gctttaacgg ggcctcctgt gaccctgtcc acgggcagtg ccactgtgcc cctggctgga   3300

tggggccctc ctgcctgcag gcctgccctg ccggcctgta cggcgacaac tgtcggcatt   3360

cctgcctctg ccagaacgga gggacctgtg accctgtctc aggccactgt gcgtgcccag   3420

agggctgggc cggcctggcc tgtgagaagg agtgcctccc ccgggacgtc agagctggct   3480

gccggcacag cggcggttgc ctcaacgggg gcctgtgtga cccgcacacg ggccgctgcc   3540

tctgcccagc cggctggact ggggacaagt gtcagagccc ctgcctgcgg ggctggtttg   3600

gagaggcctg tgcccagcgc tgcagctgcc cgcctggcgc tgcctgccac cacgtcactg   3660

gggcctgccg ctgtccccct ggcttcactg gctccggctg cgagcaggcc tgcccacccg   3720

gcagctttgg ggaggactgt gcgcagatgt gccagtgtcc cggtgagaac ccggcctgcc   3780

accctgccac cgggacctgc tcatgtgctg ctggctacca cggccccagc tgccagcaac   3840

gatgtccgcc cgggcggtat gggccaggct gtgaacagct gtgtgggtgt ctcaacgggg   3900

gctcctgtga tgcggccacg ggggcctgcc gctgccccac tgggttcctc gggacggact   3960

gcaacctcac ctgtccgcag ggccgcttcg gccccaactg cacccacgtg tgtgggtgtg   4020

ggcagggggc ggcctgcgac cctgtgaccg gcacctgcct ctgccccccg gggagagccg   4080

gcgtccgctg tgagcgaggc tgcccccaga accggtttgg cgtgggctgc gagcacacct   4140

gctcctgcag aaatgggggc ctgtgccacg ccagcaacgg cagctgctcc tgtggcctgg   4200

gctggacggg gcggcactgc gagctggcct gtccccctgg gcgctacgga gccgcctgcc   4260

atctggagtg ctcctgccac aacaacagca cgtgtgagcc tgccacgggc acctgccgct   4320

gcggccccgg cttctatggc caggcctgcg agcacccctg tccccctggc ttccacgggg   4380

ctggctgcca ggggttgtgc tggtgtcaac atggagcccc ctgcgacccc atcagtggcc   4440

gatgcctctg ccctgccggc ttccacggcc acttctgtga gagggggtgt gagccaggtt   4500

catttggaga gggctgccac cagcgctgtg actgtgacgg gggggcaccc tgtgaccctg   4560

tcaccggtct ctgcctttgc ccaccagggc gctcaggagc cacctgtaac ctggattgca   4620

gaaggggcca gtttgggccc agctgcaccc tgcactgtga ctgcgggggt ggggctgact   4680

gcgaccctgt cagtgggcag tgtcactgtg tggatggcta catggggccc acgtgccggg   4740

aaggtgggcc cctccggctc cccgagaacc cgtccttagc ccagggctca gcgggcacac   4800

tgcccgcctc cagcagaccc acatcccgga gcggtggacc agcgaggcac tagtagaggc   4860

agtcccgtgg agcccgcctc tccagtccca gccagagggg accctggcct ttggtgacca   4920

ctgagaagga cacttcacgg gcccagagct cctggtactg cccttccttt gagggccgtg   4980

gagggctgtg gacagcccag caacctgtcg ctcttggagg ctggtgtggc cttgaggagg   5040

gaagcctcgc atggccgctg gaagagaggc gcctcctggc ctggctctgc agaacccagg   5100

ggcacgctct gggcctgggc tgaggaagtc ccgctctccc cgcggctctg agttggactg   5160

aggacaggtg tgggcgccag tgtgggtgca ggcgcaggtg caggcacagg gccactgtcc   5220

tccaggcagg ctttttggtg ctaggccctg ggactggaag tcgcccagcc cgtatttatg   5280

taaaggtatt tatgggccac tgcacatgcc cgctgcagcc ctgggatcag ctggaagctg   5340

cctgtcatct cctgcccaat ccccagaaac cctgattcag gtctgcaggc tcctgcgggc   5400

tcaccaggct gctggctccg gtaccatgta aacctaggaa ggtaaaggag caggcaacct   5460

cctcgtggcc tgtgtgtttg ctgtgttacg tggactctgt gtgggctcct ccctggggcc   5520

cggccagcat aacggtgcac ccagggacct cccagtgcac ccggggccct ttgcaggggt   5580

gggggtgcca cacaagtgaa gaagttggga ctcatctcag ttcccagtgc tattgaggag   5640

aacgctgggg ctgcattcat taccgctgag acccagagac tggctgttcc cagagaatgg   5700

cccaggggga ggagggctgg tgtggagggg caacctggac tgaggccgaa ctcccttggg   5760

ctcaccccac ccacccctac ctgagcatca gcagtggggg gagggcagca tcgcaggggc   5820

agggactccc tgggtgagga cagaccagcc ctcccgagca cctggcactc atgggctgag   5880

gctgacttct cctggaagaa gggcccagag tggaaggaag aggcagaggg tagaggtggt   5940

ggctgggggc tcctctgcag agtggggtgg ccaatggaga gggctgcact cacaccgcaa   6000

cataggactc tctctccctt aagaaggccc ccttagggtc tgggctgccg cccccatcac   6060

cctaaaacca gccaaggtag ctgaggcccc agggcagaca atttcaccag caggaggagg   6120

aggagtccag tgagcttggt tgctcacaga cagcaaggga gctgtcacag aggaagctga   6180

tgaatggacc gctgtgggga gactttaaag tagaacagtg ataagggagg gcaggatggt   6240

ggggatgcag aagcagcagc cagagagaga cggactgggg tgcagacgga gtgtggaaaa   6300

cgcatacctt gaaatgaagc atccagcaga tggggtgagt ggatacagct caggagattc   6360

tcccaggaat agcagggagg cgtaaagaga gacaacgtac agagatagat gaatggaaat   6420

gggtaaggga ggtgttcatt cacatccatc taactgcaaa atacaaaagt aagaagtcat   6480

tgacatgaag caacgacgac caagacgttc tcagatctaa aggtgaatga tctcagtcag   6540

cctggaaatg cacaaggtgg aaaaataaca taaaaaagcc ataagacctt gaagaacatc   6600

aatgtcaaag ataaattcta aagtcccaga gaaaaaagaa tgggaatcaa attgacctca   6660

gactatacgt gagaaacacg gagagccaga aaactgtgat gttccatcct cagagtttga   6720

aggaaatatt tgaaggctga attttacatc cagctaaact atcaaaggca tgcaaagtcc   6780

atgttattct taggccttca aggcctcggc catttttcta cagaaaagcc tgattttaaa   6840

atgctcttag agacgttctc cagccagaag agaaagaagc caggagggtg ctctgagata   6900

ttcagtcacc acagttccca aatggcctag gaattcagag agtcagaata tcaccattac   6960

tccccaatgg gaacccccga cagtctcagc atggtgtgag ggtgtggacg gggggcctgg   7020

caggtaccaa tcactcatcc cgctcagtga agacacagtg ttcagctacg gaagccataa   7080

ggcaggccga gcttctgccc atccggagga aatctcagct atccaacggc ggtcaggagc   7140

agaggaaaat aaagcagaat aactagaaaa cacgctcaca gatcctaatg ttaacggtta   7200

caaatgacga cggaaaaaca aactcctgac catatattat atagtttcaa gcagcaagaa   7260

ggaggatatt gaacattctc aacacacata ataaacgctt gagatgatga tatgctcatt   7320

accctgattt gatcactaga catcccatgt atcaaaacat cactgtgtat ccgatgaata   7380

tctacaatta ttgtcaatta aaaacatcat taaaaacaga ctagactgca ttaaaaataa   7440

aaaaaaaaaa                                                          7450


<210>  827
<211>  7500
<212>  DNA
<213>  Human

<400>  827
agctcatggg agtatgaagg agatggtagg aggctgctgc gtatgttcgg acgagagggg     60

ctgggccgag aacccgctgg tctactgcga tgggcacgcg tgcagcgtgg ccgtccacca    120

agcttgctat ggcatcgttc aggtgccaac gggaccctgg ttctgccgga aatgtgaatc    180

tcaggagcga gcagccaggg tgaggtgtga gctgtgccca cacaaagacg gggcattgaa    240

gaggactgat aatggaggct gggcacacgt ggtgtgtgcc ctctacatcc ccgaggtgca    300

atttgccaac gtgctcacca tggagcccat cgtgctgcag tacgtgcctc atgatcgctt    360

caacaagacc tgttacatct gcgaggagca gggccgggag agcaaggcgg cctcgggagc    420

ctgcatgacc tgtaaccgcc atggatgtcg acaagctttc cacgtcacct gtgcccaaat    480

ggcaggcttg ctgtgtgagg aagaagtgct ggaggtggac aacgtcaagt actgcggcta    540

ctgcaaatac cacttcagca agatgaagac atcccggcac agcagcgggg gaggcggagg    600

aggcgctgga ggaggaggtg gcagcatggg gggaggtggc agtggtttca tctctgggag    660

gagaagccgg tcagcctcac catccacgca gcaggagaag caccccaccc accacgagag    720

gggccagaag aagagtcgaa aggacaaaga acgccttaag cagaagcaca agaagcggcc    780

tgagtcgccc cccagcatcc tcaccccgcc cgtggtcccc actgctgaca aggtctcctc    840

ctcggcttcc tcttcctccc accacgaggc cagcacgcag gagacctctg agagcagcag    900

ggagtcaaag gggaaaaagt cttccagcca tagcctgagt cataaaggga agaaactgag    960

cagtgggaaa ggtgtgagca gttttacctc cgcctcctct tcttcctcct cctcttcctc   1020

ctcctctggg gggcccttcc agcctgcagt ctcgtccctg cagagctccc ctgacttctc   1080

tgcattcccc aagctggagc agccagagga ggacaagtac tccaagccca cagcccccgc   1140

cccttcagcc cctccttctc cctcagctcc cgagcccccc aaggctgacc tttttgagca   1200

gaaggtggtc ttctctggct ttgggcccat catgcgcttc tccaccacca cctccagctc   1260

aggccgggcc cgggcgccct cccctgggga ctataagtct ccccacgtca cggggtctgg   1320

ggcctcggca ggcacccaca aacggatgcc cgcactgagt gccacccctg tgcctgctga   1380

tgagacccct gagacaggcc tgaaggagaa gaagcacaaa gccagcaaga ggagccgcca   1440

tgggccaggc cgtcccaagg gcagccggaa caaggagggc actgggggcc cagctgcccc   1500

atccttgccc agtgcccagc tggctggctt taccgccact gctgcctcac ccttctctgg   1560

aggttccctg gtcagctccg gcctgggagg tctgtcctcc cgaacctttg ggccttctgg   1620

gagcttgccc agcttgagcc tggagtcccc cttactaggg gcaggcatct acaccagtaa   1680

taaggacccc atctcccaca gtggcgggat gctgcgggct gtctgcagca cccctctctc   1740

ctccagcctc ctggggcccc cagggacctc ggccctgccc cgcctcagcc gctccccgtt   1800

caccagcacc ctcccctcct cttctgcttc tatctccacc actcaggtgt tttctctggc   1860

tggctctacc tttagcctcc cttctaccca catctttgga acccccatgg gtgccgttaa   1920

tcccctcctc tcccaagctg agagcagcca cacagagcca gacctggagg actgcagctt   1980

ccggtgtcgg gggacctccc ctcaggagag tctgtcttcc atgtccccca tcagcagcct   2040

ccccgcactc ttcgaccaga cagcctctgc accctgtggg ggcggccagt tagacccggc   2100

ggccccaggg acgactaaca tggagcagct tctggagaag cagggcgacg gggaggccgg   2160

cgtcaacatc gtggagatgc tgaaggcgct gcacgcgctg cagaaggaga accagcggct   2220

gcaagagcag atcctgagcc tgacggccaa aaaggagcgg ctgcagattc tcaacgtgca   2280

gctctctgtg cccttccctg ccctgcctgc tgccctgcct gccgccaacg gccctgtccc   2340

tgggccctat ggcctgcctc cccaagccgg cagcagcgac tccttgagca ccagcaagag   2400

ccctccggga aagagcagcc tcggcctgga caactcgctg tccacttctt ctgaggaccc   2460

acactcaggc tgcccgagcc gcagcagctc gtcgctgtcc ttccacagca cgcccccacc   2520

gctgcccctc ctccagcaga gccctgccac tctgcccctg gccctgcctg gggcccctgc   2580

cccactcccg ccccagccgc agaacgggtt gggccgggca cccggggcag cggggctggg   2640

ggccatgccc atggctgagg ggctgttggg ggggctggca ggcagtgggg gcctgcccct   2700

caatgggctc cttggggggt tgaatggggc cgctgccccc aaccccgcaa gcttgagcca   2760

ggctggcggg gcccccacgc tgcagctgcc aggctgtctc aacagcctta cagagcagca   2820

gagacatctc cttcagcagc aagagcagca gctccagcaa ctccagcagc tcctggcctc   2880

cccgcagctg accccggaac accagactgt tgtctaccag atgatccagc agatccagca   2940

gaaacgggag ctgcagcgcc tgcagatggc tgggggctcc cagctgccca tggccagcct   3000

gctggcagga agctccaccc cgctgctgtc tgcgggtacc cctggcctgc tgcccacagc   3060

gtctgctcca cccctgctgc ccgctggagc cctagtggct ccctcgcttg gcaacaacac   3120

aagtctcatg gccgcagcag ctgcagctgc agcagtagca gcagcaggcg gacctccagt   3180

cctcactgcc cagaccaacc ccttcctcag cctgtcggga gcagagggca gtggcggtgg   3240

ccccaaagga gggaccgctg acaaaggagc ctcagccaac caggaaaaag gctaaatcca   3300

cccttacccc tcctgacccc cccaagtgga gggaacagat cctggcctga ggggtcctag   3360

cctggagcag gcgcctgcgc ccagaccctg gagagccttg acccagagcc tgtgctgagg   3420

tccagggagt gtggagagct cctggtgtcg aggactgaga ctgagagggg agccccctcc   3480

atctggcccc cttccctttc cgcactgtcc gctttgtgag gctcagagga aggacagtct   3540

gcaagcccgc ctaggaggtc catccccagc aaatgttttg gaggtccccc cagagagcag   3600

agtgggccat ggcagaagta gggggttggt tggacctgtc acatgaaatg gatcagcact   3660

tgaatgggga gaagtggagg gagaggccct gggcctgtcc ctgcggggaa atcttttatg   3720

gaagaagggc tggacccact ttacctgcag tttcttccca gctcgggcag atggcagaag   3780

ggaccccttg gactttttct cgccatccct ccccccagcg caggggcaca agctgagctt   3840

gtaaaagccc acagatgttg ggggctggag aaggggcagg agagcatcac actcagcccc   3900

agcctcctca acctcttggg gccccgtgat ggggaggaga gggcaggtgc ggggaggctc   3960

tggccttcct tggtgccccg ccctttgttt gcactattgg acttaggagt gccgagggtg   4020

gggagatgga gctgcccgtc tcagtgtgtg agtgtgtgtg tgcgtgcatg tgtgtgtgtg   4080

tgtgtgtgtg tgtgtgtgtc tgtctgcctg tctctctcct cctggaccca gggcagccaa   4140

gggcagggat aggcgcagtg gtcagatgaa gcagcgccag agaggggacc tcccagctct   4200

tatttgcacc ctccccacct caccaacttt ggtccctctc tgggggcatg aatggttaac   4260

aaacaccaga gcagtactcc aatattggag agtcgctggg ggcacagggc tttgaatcag   4320

ggtagtatcc tgccttccct cccctgaccc cacatggtct cagggccccc ttagggcccc   4380

ctaccccact gatagcttcc tccttctctg gcacaagggg agccccaggg cttgggggag   4440

ggcgtaaggt ggggggaaat gccactgctt ttagcaaaag cctccctccc agaattagcc   4500

agcttgcctc ctgcacccca cccccaccaa ccaggggagc cactaagctg actaacaact   4560

gtcccctcac ccaccagcta tttccccagg gtagagtggg caattctcac cttcaaagag   4620

tccccgcctg cccaggcctt tggcacagag gctgagtgga cagtcaggag agaggcgaga   4680

ggcaaggcga agcctgtgtc cctgtttcag ttgcactggg gttggagccc agggtagggg   4740

tttccagctt ccccaggctc cggccttgtc agtctctttg catgtgtgga tttttctgtg   4800

tgtgtttctg tttgggtttt tgttgttggg tttttttttt ttttttaata aagaaaagaa   4860

gatgtgtata tttttggcaa cgacagaaac gtagtgcaga tatatttttg cctgtgctgc   4920

tcaactgttt tttttttctg atactgaaaa taatattaat attcctgttg ataagacttt   4980

gtaagatgtt agggagctga taatggaggg gggtgggaat ccttcaaagg caatttctta   5040

ggcacttgca agggcttggg ggagggggag gcagttgtga tgacctcaga aatactcact   5100

ttttattaat gctaaatatg ttagaaagaa atgatagcat tcagcatttt attcttctta   5160

atctattaag ctgtgtaact ccctgcccca aaccactgaa aagaaaagta accttcaggc   5220

caggcgcggt ggctcacgcc tgtaatccca acactttggg aggctgaggc gggcggatca   5280

cttaaggtca ggagttcaag accagcctgg ccaacatggt gaaaccccgt ctctatcaaa   5340

aattagccgg gcatggtggc acgtgcctgt aatcccagct acttgggagg ctgaggcacg   5400

agaattgctt gaacccagga ggctgaggct gcagtgagcc aagattgtgc cactgcactc   5460

cagcctgtgt gagagagtga gactctgtct caaaagagaa aaaaaaagaa aagtaacctt   5520

cagagattct tagaagagtt gctcattcac acccacgccc ttgcccaagg ctggcccact   5580

tagagcgaaa cttaactttt gtctggatgg gaagagaagt aagtctaccc cgaggttgcc   5640

atgttgaaga gtgagaggtc caagtgattc tgtgcattga aaccaagaca ccccacccag   5700

aacacttctt ccctccctca gcccaaacca aaggctgggg ttctcatctc caagtggctg   5760

ttctccaact ttcccaagcc gcttgcattc cccagactgg actactgtgg cggttaggtt   5820

agatttgaag acggggccca ggctgggtat gaacgggtgc agccctcttc tcctcttccc   5880

ccccacatct ctcatgagag aggtagtggc atttccttct cagggagctt caatgggaaa   5940

ggtctcgaaa gcttcaggag gagcagaata ccaacgcagg gggatggctg taacgatctc   6000

accgtctcct aacctcagtc ccttttttga gagtgaatgg tggagggtgg gaagggaccc   6060

agatttgtag atctctttgt ctgggggagg ggaaggatgt ggtttgcaga gcggaagcag   6120

agtttggaaa cgcatgagag cagagcttcg tgtgttccca ccctcagtga ggaggtgtga   6180

gtgggtgagc atgtggagtt gggtgttccc accctcagtg aggaggtgtg agtgggggtg   6240

catatagagg cagtgcctgc tgtggggtca caactggtgc atgccagcgc caaagggacc   6300

tgtctttagg ggtcatttca gccagctcct cccatcacag atgacagctc caagcctaga   6360

aggggctcag tgacagggcc aggacaagcc ctcaggactg tggcctcctg gcccttggtt   6420

cccctgcccc acaacatggt ctccacatgg ctggctggct ggctgtccct gtgtgtgtgt   6480

gacacacggt gtgagtgcag ggctgtgccc ggggtgggag ggtgtctatg tggcactgac   6540

tgtcttagct cagagctggt ggatcctctc catggacaat gacactttaa ggattgtctt   6600

ggtttgtttt tcctatttgt ggggtatttt ccccctcagg ctcctgggtc tgctgctgcc   6660

tcaaggtgtc ctgaccttga ggctgatgag gggacccctg cctgtttccc ccatactgag   6720

ttctagggag gtgctcaccc cagactctta ggaagggtct agagaaatga gaggagccca   6780

agccaggggc cagctccgag aaagggtaac ctccacgctt ctctctccca aattggaaat   6840

gaagacaggt tttcaaaggc acaggctccc cctgccagct tctaggatct tccttggtgt   6900

gcaatgggcc agttaggggt aggcagcttg cacccagttc tcctttatct caacttattt   6960

tcctggggag aggtgcctag agggattgag gtaacttcaa ctgggaattc caaggaaggt   7020

gggcaagtag ccttggctct ctcccaccat gtccatcagg attgagagtg tgtctagctc   7080

ccgaccactt tgtcttgacc tactgaaaag ttgggaactg aggggtgcct tcattcccct   7140

ttgttcactt tctccagctc aacttgggac ttgggtggtg ggactggaga cctcacccct   7200

gctcccgtcc cgcccccttt ctatcccaac ctgtttccat gtagcagacc cttcctaggg   7260

agcagggagg ggaagccaca gattgcaaac ccaggggctc ctttttcatt ctttctaaaa   7320

ccttgatatc ctcagcccaa aggcgatgcc cccctgccac ctccaagcct ggaattgtgc   7380

ataacccgga tcttgtatct ttgtataacg gatgttattt gtacgaaggg cagttcgtaa   7440

acagcacttg ttcttttaat aaaagaatgt tttgcaaaaa aaaaaaaaaa aatccgaaga   7500


<210>  828
<211>  1101
<212>  DNA
<213>  Human

<400>  828
atgtgcggtg aggctcgcgg ccggagtgcg gcgctgggcg gaagctacca tggcggccga     60

gcgaaagaca aggttgtcca agaatctact gcgcatgaag tttatgcaaa ggggactgga    120

ctcagaaacc aagaaacaac tagaagaaga agaaaagaaa atcattagtg aagagcactg    180

gtacttggat ttgccagagc ttaaagagaa agagagtttc ataatagaag agcagagttt    240

cttactatgt gaagatcttc tctatggaag aatgtcattc agaggattta atcctgaggt    300

tgagaaattg atgcttcaga tgaatgctaa gcacaaagca gaagaagttg aagatgaaac    360

agtagagctt gatgtgtcag atgaagagat ggctagaaga tatgagacct tggtggggac    420

aattgggaaa aagtttgcca gaaagagaga ccatgccaat tatgaagaag atgaaaatgg    480

agacataaca ccaattaaag caaagaagat gttcttaaag ccccaggatt aagatggatg    540

ccttaagcga tggcccaggg gtgcttggtg gaagtcagca gggcatctgg agctcatccc    600

aatggtgtct ctatagttat taatactgta acgtttactt gtaaagagat tatcatttta    660

gaaacatgct gtttttgaaa cagatgtgtg atggatgttg tacatccttt gcttcttggt    720

attcattcag agtggatttt tagcccctga tctacaaatg tacattgtta cagggctgct    780

tcctaaagat tttttttacc tcaggtttct cttaatatag ttctccagtc actgaccttg    840

aattgactta cataaactac tgccaatgtt taaattgccc ttatgtttat atttattatg    900

tcaagccaat tcgtacatac aatttggaat caaatgtcat aagaatttat tatataaatt    960

tatcaagaat aaaaatgcct ctccagcctt aagtatttac atgctcccag gtcattgtca   1020

gtttatggta ttatgttgtt ttatttaaag cattgaattg atagaaaaat ttgctctgta   1080

ataaaaatct actttcacat a                                             1101


<210>  829
<211>  1344
<212>  DNA
<213>  Human

<400>  829
agagagggcg gggacgtgtt tggcagcggg acgcaccatt tcagttgtgt tcttggttca     60

tttcgtgtct cggcgatgtt tcctagagtc tcgacgttcc tacctcttcg ccccctttcc    120

cgccaccctt tgtcctctgg aagcccggag acatcagcgg ctgcgattat gctactcact    180

gttcggcacg gaacagtcag gtaccgcagt tcagcgctgt tggcccggac aaaaaataac    240

atccaaagat attttggcac taacagtgtg atctgtagca agaaagataa gcagtctgtt    300

cgaactgagg agacttccaa ggagacttca gagagccaag acagtgaaaa ggaaaatacg    360

aaaaaagact tgttaggcat tattaagggc atgaaagttg aattaagcac agtaaatgta    420

cgaacaacaa agccccccaa aagaagacca cttaaaagtt tggaagctac acttggcagg    480

cttcgaagag ctacagaata tgctccaaag aagagaattg agcccctgag tcctgagttg    540

gtggcagctg catctgctgt ggcagattct ctcccttttg ataagcaaac aaccaagtca    600

gagctgctga gccagctcca gcagcatgag gaagagtcaa gggcacagag agatgcaaag    660

cgacctaaaa ttagtttcag taacataata tcagatatga aagttgccag atctgctaca    720

gctagagttc gttcaagacc agagcttcgg attcagtttg atgaaggcta tgacaattat    780

cctggccagg agaagacgga tgatcttaaa aaaaggaaaa atatattcac agggaaaaga    840

cttaatattt ttgacatgat ggcagttact aaagaagcac ctgaaacaga cacatcacct    900

tcactttggg atgtggaatt tgctaagcag ttagccacag taaatgaaca accccttcag    960

aatggatttg aagagctgat ccagtggaca aaagagggga aactatggga gttcccaatt   1020

aacaatgaag caggttttga tgatgatggt tcagaatttc atgaacatat atttctggag   1080

aaacacctgg agagctttcc aaaacaagga ccaattcgcc acttcatgga gctggtgact   1140

tgtggccttt ccaaaaaccc atatcttagt gttaaacaga aggttgaaca catagagtgg   1200

tttagaaatt attttaatga aaaaaaggat attctaaaag aaagtaacat acagttcaat   1260

taagaccatg gaaattttta tttcaaacaa ttagagatgg atattacaac taaataaaat   1320

aattttacta gagtttgtaa aaaa                                          1344


<210>  830
<211>  4119
<212>  DNA
<213>  Human

<400>  830
cgcggggagc ggcggcggcg gcggcggcgg cggtggcgga ggcggacaca ttggcgtgag     60

acctgggagt acgttgtgcc aaatcattgc cacttgccac atgagtgtaa atgatggcgg    120

atgccaagta tgtcctctgc cgatgggaaa agcgattatg gcctgcgaag gttttggccc    180

gaaccgcgac ttcaacaaaa aataagagaa gaaaggaata ttttctagct gtgcaaatcc    240

tctctctaga ggaaaaaatt aaggtgaaaa gcactgaagt tgagatccta gagaagtctc    300

aaattgaagc cattgcttcc tcgttagcct cacagaatga ggttcctgcg gcacccctgg    360

aagaactggc ctacagacgg tcgcttcgcg tggctctgga cgttctgagc gagggctcga    420

tttggagtca agaaagctct gcagggacag gtagagctga ccggtctctg cgagggaagc    480

ccatggagca tgtctcctcg ccctgtgatt cgaactcctc atctcttccc cgcggagacg    540

tgttgggcag ttccagacct cacaggagga ggccatgtgt gcaacaaagc ctgtcaagtt    600

cgttcacttg tgaaaaggac cccgagtgca aagtggacca caagaagggg ctcaggaaaa    660

gtgaaaaccc aagaggcccg ttggtcctcc cagctggagg tggtgcccaa gatgagagtg    720

ggtccagaat ccaccacaaa aattggactc ttgcaagtaa gaggggagga aactcagcgc    780

agaaggctag cttgtgcctg aatggatctt ccctttcaga ggacgacacg gagagagaca    840

tggggagcaa aggaggcagc tgggcagccc cgtccttgcc ctccggggtc agggaggacg    900

atccctgtgc caacgctgag ggacacgacc ccggtctgcc gttgggcagc ctcactgcgc    960

ccccagcccc tgagccctcg gcctgctcag agcctggaga atgccctgcg aaaaagaggc   1020

cgcgcctgga tggcagccaa aggccgcctg ccgtgcagct ggagcccatg gcagcagggg   1080

ccgcaccatc ccccgggccg gggccagggc ccagagagtc tgtgaccccg cgcagcaccg   1140

ccaggctggg cccgcctccc tcccacgcct ctgcggatgc aaccagatgt cttccttgcc   1200

cggattccca gaagctggag aaagagtgcc agtcttccga agagtccatg gggtctaatt   1260

ccatgcgttc tatcctggag gaagacgagg aagacgagga gccaccaaga gtccttttat   1320

accacgaacc acgttcgttt gaagtaggaa tgctagtctg gcataaacat aaaaaatacc   1380

ccttctggcc agcagtggtc aaaagcgtca ggcagagaga taagaaagca agtgtgctat   1440

acatcgaagg acacatgaac ccgaaaatga aaggtttcac agtgtctctt aaaagtttaa   1500

agcactttga ttgtaaagag aaacagacgc ttctgaatca agccagggag gacttcaacc   1560

aggacatcgg ctggtgtgtc tccctcatca ccgactacag ggtccggtta ggctgcgggt   1620

cttttgctgg ctctttcctg gaatattacg cggctgatat aagctatcct gtccgaaaat   1680

ccatccagca ggacgtcttg gggaccaagc ttcctcaact gagcaagggg agccccgagg   1740

agcccgtggt ggggtgcccc ctggggcaga ggcagccctg ccggaaaatg ctccccgacc   1800

gctcgcgggc cgcccgggac cgggccaacc agaagctggt ggagtacatt gtgaaggcca   1860

agggcgcgga gagccacctg cgggccatcc taaagagcag gaagccatct cgctggctgc   1920

agaccttcct gagctccagc cagtacgtga cctgtgtgga gacctacctg gaggatgagg   1980

ggcagctgga cctggtggtg aagtacctgc agggcgtcta ccaggaggtg ggggccaagg   2040

tgctccagcg caccaacggc gaccggatcc ggttcattct ggacgtgctt ctgcccgagg   2100

ccatcatctg tgcgatctct gcggtggacg aggtggacta caagacggct gaggagaagt   2160

acatcaaggg gccttcgctg agctaccggg aaaaagaaat atttgacaac cagctccttg   2220

aagagcggaa ccggcgccgt cggtgaggga gcagccggct gtgctgtcag cggggcctgg   2280

cggtggaagc gcctccagtg tgcatgagcg tgtctgaaga tggggggctc agggggcacg   2340

tttgcgtttg gacctgtctg tgcgttctcc tgcgtggcag tcctgatttc catgcttctg   2400

gagaatccat ttcgttaaca ctgaaagcca gttctctttt cctggcagtt tttttcattt   2460

tatttttggc attttttaca agataccgtt cgggaaaggc ttttgaaagg acggaagcgt   2520

attcactgtg cgccagtact cctggctgtg ctgtggtttc tcccgacgtg cacatcgatc   2580

tcgtatgtgt ggcatctgat attaaacggg aggttttaag aagcgtctgc cgtgatcatg   2640

gagcttcgga agcgggaatg gttcttccgg gtttgctgtt ttgtctgttt cccccttgtg   2700

tggtttccgc ctgcgacagt tccagaattt gctctcccac tcagtgtgct ctgcagctgt   2760

gaggaaacag ccttcgttag aggcgggagc agagacgagc cgctgctctg tgtcgtgttt   2820

gctgtggccg cagggagagg agcaggacac gcacctttcc aggggcctct gtgtcccgca   2880

ctgtgtgtga gtggaccgca gcgcgcagcc acatgccctg gctgccatgg gccagaccgc   2940

ctccacctcc cccgcccgcc tggcctgtcc tgagtgcatt tccctgcact gtgtcgtcac   3000

tgcacagcca gtcaccgcgg tctcagtcat cggcgcggat ggctatgctg gggtcccagg   3060

gtggccgcag cagtcagggt cactgtggga gccctggggt ggagtgacaa accgcattgt   3120

cctgtgcccg ccatggcaga agcgcagcct ttgtatggag gcccaaccgc gctcccgtct   3180

ggagaagcgg cttccggggt gtggctgccg ggtcggctct ggtccacagc acggtgccgg   3240

ggctgcaggt tgttgagggc tgtgactccg tggggctcag ccaggctcca gcagggtcag   3300

acgtgctgtt aagagcaaag ccacagacga tgacttgtcc attctcagtg gatgctccag   3360

gctgtgccta cacagcagtg ctggtgacat gtccagggtt ccagggcccg gtggcctggg   3420

agctgctttc tccccactgg ctgggctgca tctggccctg gctggaggcc ttgctttgag   3480

gggctgtgac cctcttcccc caggccctcc ccagccgacg acagccaccg gagaggagat   3540

cggaacacga ttgtctcaga tgcagggcgc tgtgcgggac gaagccgcaa ggactctcgt   3600

atcgggccct tgggactcgg gaggtgccag aggcggcggc tgctctggac ctcggtgttc   3660

actgaccttt gtttcacttg cctctgctcg actccgagag caggaaaccc ggccgtggcc   3720

tggcagctcc gcctcccatg cccgcacgct ggggtctgtc ttgtctggag cagtggggca   3780

caccccggag gaggcggggg tcagggctgt cggccttggc cccctgctgg tcgctgtttc   3840

ggggactcgg ggcggccagt accaccgcct gaggcggggc tcagcagcgt tgcatgtacg   3900

ggcctcgtac tgcctcatgg aaaatcctcc ggagccgccc tccattgtgg gttcctgaga   3960

gtaggacaca ttgccatggt tttgtgggaa tcacgcgccc ctgatggaac ttttctgctg   4020

ttgtgaagta cttttatcca tttgcttctc tgctgacctt gccaagttgt tcgaggtgga   4080

attaaacacc tcccagacct caaaaaaaaa aaaaaaaaa                          4119


<210>  831
<211>  2212
<212>  DNA
<213>  Human

<400>  831
gctccgtgtt ggaggcactg tcaggagttg cccttcccag aggcagcggg atcgtgacca     60

gatgcccgct ggtgctgaaa ctgaagaaac ttgtgaacga agataagtgg agaggcaagg    120

tcagttacca ggactacgag attgagattt cggatgcttc agaggtagaa aaggaaatta    180

ataaagccca gaatgccatc gccggggaag gaatgggaat cagtcatgag ctaatcaccc    240

tggagatcag ctcccgagat gtcccggatc tgactctaat agaccttcct ggcataacca    300

gagtggctgt gggcaatcag cctgctgaca ttgggtataa gatcaagaca ctcatcaaga    360

agtacatcca gaggcaggag acaatcagcc tggtggtggt ccccagtaat gtggacattg    420

ccaccacaga ggctctcagc atggcccagg aggtggaccc cgagggagac aggaccatcg    480

gaatcttgac gaagcctgat ctggtggaca aaggaactga agacaaggtt gtggacgtgg    540

tgcggaacct cgtgttccac ctgaagaagg gttacatgat tgtcaagtgc cggggccagc    600

aggagatcca ggaccagctg agcctgtccg aagccctgca gagagagaag atcttctttg    660

agaaccaccc atatttcagg gatctgctgg aggaaggaaa ggccacggtt ccctgcctgg    720

cagaaaaact taccagcgag ctcatcacac atatctgtaa atctctgccc ctgttagaaa    780

atcaaatcaa ggagactcac cagagaataa cagaggagct acaaaagtat ggtgtcgaca    840

taccggaaga cgaaaatgaa aaaatgttct tcctgataga taaaattaat gcctttaatc    900

aggacatcac tgctctcatg caaggagagg aaactgtagg ggaggaagac attcggctgt    960

ttaccagact ccgacacgag ttccacaaat ggagtacaat aattgaaaac aattttcaag   1020

aaggccataa aattttgagt agaaaaatcc agaaatttga aaatcagtat cgtggtagag   1080

agctgccagg ctttgtgaat tacaggacat ttgagacaat cgtgaaacag caaatcaagg   1140

cactggaaga gccggctgtg gatatgctac acaccgtgac ggatatggtc cggcttgctt   1200

tcacagatgt ttcgataaaa aattttgaag agttttttaa cctccacaga accgccaagt   1260

ccaaaattga agacattaga gcagaacaag agagagaagg tgagaagctg atccgcctcc   1320

acttccagat ggaacagatt gtctactgcc aggaccaggt atacaggggt gcattgcaga   1380

aggtcagaga gaaggagctg gaagaagaaa agaagaagaa atcctgggat tttggggctt   1440

tccaatccag ctcggcaaca gactcttcca tggaggagat ctttcagcac ctgatggcct   1500

atcaccagga ggccagcaag cgcatctcca gccacatccc tttgatcatc cagttcttca   1560

tgctccagac gtacggccag cagcttcaga aggccatgct gcagctcctg caggacaagg   1620

acacctacag ctggctcctg aaggagcgga gcgacaccag cgacaagcgg aagttcctga   1680

aggagcggct tgcacggctg acgcaggctc ggcgccggct tgcccagttc cccggttaac   1740

cacactctgt ccagccccgt agacgtgcac gcacactgtc tgcccccgtt cccgggtagc   1800

cactggactg acgacttgag tgctcagtag tcagactgga tagtccgtct ctgcttatcc   1860

gttagccgtg gtgatttagc aggaagctgt gagagcagtt tggtttctag catgaagaca   1920

gagccccacc ctcagatgca catgagctgg cggggatgaa ggatgctgtc ttcgtactgg   1980

gaaagggatt ttcagccctc agaatcgctc caccttgcag ctctcccctt ctctgtattc   2040

ctagaaactg acacatgctg aacatcacag cttatttcct catttttata atgtcccttc   2100

acaaacccag tgttttagga gcatgagtgc cgtgtgtgtg cgtcctgtcg gagccctgtc   2160

tcctctctct gtaataaact catttctagc agaaaaaaaa aaaaaaaaaa aa           2212


<210>  832
<211>  741
<212>  DNA
<213>  Human

<400>  832
gcagccgccc tcggcgtcct ctgtagcggg cgacctaggc cgcgggaccc ggacggaggt     60

agaggccagg gcagcgcgtc cgggagcgga gtccgcgccc gccgccgcca tgccggacag    120

ctgggacaag gatgtgtacc ctgagccccc gcgccgcacg ccggtgcagc ccaatcccat    180

cgtctacatg atgaaagcgt tcgacctcat cgtggaccga cccgtgaccc tcgtgagaga    240

atttatagag cggcagcacg caaagaacag gtattactac taccaccggc agtaccgccg    300

cgtgccagac atcactgagt gcaaggagga ggacatcatg tgcatgtatg aagccgaaat    360

gcagtggaag agggactaca aagtcgacca agaaattatc aacattatgc aggatcggct    420

caaagcctgt cagcagaggg aaggacagaa ctaccagcag aactgtatca aggaagtgga    480

gcagttcacc caggtggcca aggcctacca ggaccgctat caggacctgg gggcctacag    540

ttctgccagg aagtgcctgg ccaaacagag gcagaggatg ctgcaagaga gaaaagctgc    600

aaaagaggcc gccgctgcca cctcctgagg cagctgtggg tgcccctgct gtgtggctct    660

gtatgactgt tgctgaaata taaagccctg caacctgaaa aaaaaaaaaa aaaaaaaaaa    720

aaaaaaaaaa aaaaaaaaaa a                                              741


<210>  833
<211>  4519
<212>  DNA
<213>  Human

<400>  833
cgcggcgatc cgagcatgag cctggagcgc gagcttcgcc agctgagcaa ggcgaaagcc     60

aaggcgcaga gggccgggca gcggcgcgaa gaggccgcgc tgtgccacca gctgggggag    120

ctcctggccg gccatggccg ctacgccgag gctctggagc agcactggca ggagctgcag    180

cttcgggagc gcgctgacga ccctctgggc tgtgccgtgg cccaccgcaa gatcggagag    240

cgcctggccg agatggagga ctacccggct gccttgcagc accagcacca gtacctggag    300

ctggcacatt ccctgcgcaa ccacacggag ctgcagaggg cctgggccac catcggccgc    360

acccacctgg acatctatga ccactgccag tcgagggatg ctttgctgca ggcacaggct    420

gcctttgaga agagcttggc tattgtggat gaggagctgg aggggacact ggcccaggga    480

gagctgaatg agatgaggac ccgcctctat ctcaacctgg gcctcacctt tgagagcctg    540

cagcagacag ccctgtgcaa cgattacttc aggaagagca tcttccttgc ggagcagaac    600

cacctttacg aggacctatt ccgcgcccgc tacaacctgg gcaccatcca ctggcgcgcg    660

ggccagcact cccaggctat gcgctgcttg gagggtgccc gggagtgtgc gcacaccatg    720

aggaagcggt tcatggagag cgagtgctgc gtggttattg cacaggtcct ccaagacctg    780

ggagactttt tggctgccaa gcgagccctg aagaaggcct acaggctggg ctcccagaag    840

cctgtgcaga gggcagccat ctgtcagaac ctccagcatg tgctggcagt ggtccggctg    900

cagcaacagc tggaagaggc tgagggcaga gaccctcagg gtgccatggt catctgtgag    960

cagctagggg acctcttctc caaggcagga gactttccca gggcagctga ggcttaccag   1020

aagcagctgc gttttgctga gctgctggac agaccgggtg ctgagcgggc catcatccac   1080

gtgtccctgg ccaccacact gggagacatg aaggaccacc atggggccgt gcgccactat   1140

gaggaggaac tgaggctgcg cagcggcaac gtgctggagg aggccaagac ctggctgaac   1200

attgcactgt cccgcgagga ggccggcgat gcctacgagc tgctggcccc gtgcttccag   1260

aaagcgctca gctgtgccca gcaggcccag cgtccccagc tgcagaggca ggtcttgcag   1320

catctccata ccgtgcagct gaggctgcag ccccaggagg cccctgagac cgaaaccaga   1380

ctacgggagc tcagtgtagc tgaagatgaa gatgaggagg aggaggcgga ggaggcggca   1440

gccacagcgg agagcgaagc cctggaggcc ggcgaggtgg agctctcaga gggcgaggac   1500

gacaccgatg gcctgacccc gcagctggag gaggacgagg agcttcaggg ccacctgggc   1560

cggcggaagg ggagcaagtg gaaccggcga aacgacatgg gggagaccct gctgcaccga   1620

gcctgcatcg agggccagct gcgccgcgtc caggaccttg tgaggcaggg ccaccccctt   1680

aaccctcggg actactgtgg ctggacacct ctgcacgagg cctgcaacta cgggcatcta   1740

gaaattgtcc gcttcctgct ggaccacggg gccgcagtgg acgacccagg tggccagggc   1800

tgcgaaggca tcacccccct ccacgatgcc ctcaactgtg gccacttcga ggtggctgag   1860

ctgctgcttg aacggggggc gtccgtcacc ctccgcactc gaaagggcct cagcccgctg   1920

gagacgctgc agcagtgggt gaagctgtac cgcagggacc tggacctgga gacgcggcag   1980

aaggccaggg ccatggagat gctgctccag gcggctgcct cgggccaaga tccccacagc   2040

tcccaggcct tccacacccc aagcagcctt ctgtttgacc ccgagacctc tcctcctttg   2100

agcccctgcc cagaaccccc ctctaatagc actagactcc cagaggcctc tcaggcccat   2160

gtcagggtct ccccagggca ggcggcacca gccatggcca ggcctcggag gagcaggcat   2220

gggccagcca gcagcagcag cagctcagaa ggcgaggaca gcgcaggccc cgcacggccg   2280

tcccagaaga ggcctcggtg ctcggccaca gcacaacggg tggcagcctg gacgcctggc   2340

cccgccagca acagggaagc agccacagcc agcaccagcc gggcagccta ccaggcagcc   2400

atccggggtg tgggcagtgc tcagagccgg ctggggcctg gcccaccgcg gggccacagc   2460

aaagcccttg ccccccaggc agcgctcatc ccggaggagg agtgcctggc cggggactgg   2520

ctggagctgg acatgcccct gacccgcagc cgccggcccc gcccccgggg cactggagac   2580

aaccgcaggc ccagtagtac ctctgggtcg gacagtgagg agagcaggcc ccgtgcccga   2640

gccaagcagg tccgcctgac ctgcatgcag agttgcagtg cgccagttaa cgcagggccc   2700

agcagcctgg cttcagaacc tccagggagc cccagcaccc ccagggtctc agagcccagt   2760

ggggacagct ctgcggcagg ccagcccttg ggtccggccc cgccccctcc catccgggtt   2820

cgagttcaag ttcaggatca tctcttcctc atccctgtcc cacacagcag tgacacccac   2880

tctgtggcct ggctggccga gcaggcggcc cagcgctact accagacctg cgggctgctg   2940

cccaggctca ccctacggaa agagggggcc ctgctggccc cacaggacct catccctgat   3000

gtgctgcaga gcaatgacga ggtgttggct gaggtgactt cgtgggacct gcccccgttg   3060

actgaccgct accgcagggc ctgccagagc ctggggcaag gggagcacca acaggtgctg   3120

caggccgtgg agctccaggg cttgggcctc tcgttcagcg cctgctccct ggccctggac   3180

caggcccagc ttacacccct gctgcgggcc ctcaagctgc acacagcact ccgggagctg   3240

cgcctggcag ggaaccggct gggggacaag tgtgtggctg agctggtggc tgccctgggc   3300

accatgccca gcctggccct ccttgacctc tcctccaatc acctgggtcc cgaaggcctg   3360

cgccagcttg ccatggggct cccaggccaa gccaccttgc agagtttgga ggagctggac   3420

ttaagcatga accccctggg ggacggctgt ggccagtccc tggcctccct cctgcacgcc   3480

tgccccttac tcagcaccct gcgcctgcag gcgtgtggct tcggccccag cttctttctg   3540

agccaccaga cagcactggg tagtgctttc caagatgctg agcacctgaa gaccctgtcc   3600

ctgtcctaca acgccctggg agcccctgcc ctggccagga ccctgcagag cctgcccgcc   3660

ggcaccctcc tgcacttaga gctcagctcc gtggcagccg gcaagggtga ttcggacctc   3720

atggagcctg tattccgata cctggccaag gaaggctgtg ctctagccca cctgaccctg   3780

tctgcaaacc acctggggga caaggctgtt agagacctgt gcagatgtct ctctctgtgc   3840

ccctcactca tctcactgga tctgtctgcc aaccctgaga tcagctgtgc cagcttggaa   3900

gagctcctgt ccaccctcca aaagcggccc caaggcctta gcttccttgg cctgtcaggc   3960

tgcgccgtcc agggtcccct gggcctgggc ctgtgggaca agatagccgc gcagctccgg   4020

gaactgcagc tgtgcagcag acgcctctgc gctgaggaca gggacgccct gcgccagctg   4080

cagcccagtc ggccgggccc cggcgagtgc acgctggacc acggctccaa gctcttcttt   4140

cggcgcctct gaccctggcg ctgcctttcc ccaccctcac cgaagcccct aataaatgaa   4200

gctgctggcc gggcgcggtg gctcacgcct gtaatcccaa cactttggga ggcccaggcg   4260

ggcggatcac gaggtcagga gatcgagacc atcctggcta acatggtgaa accccgtctc   4320

tactaaaaat accaaaaatt agccgggcgt ggtggtggaa gcctgtagtc ccagctactc   4380

cggaggctga ggcaggagaa tggcgtgaac ccgggaggcg gagcttgcag tgagccgaga   4440

tcgcaccact gcactccagc ctgggcgaca gaccgagact ccgtctcaaa aaaaaaaaaa   4500

aataaaataa atgaaaaaa                                                4519


<210>  834
<211>  5252
<212>  DNA
<213>  Human

<400>  834
aggcggggcc aagatggcgg cgcagcgcgc ggcgggggcg acgggcggcg ggggccgggg     60

ggcggtggga cgttgacccc gccccctgct gctgctagtc tgcgccgggc ggcggtggcg    120

gcggagaccc gaacatggcg accgcgcgca ccttcgggcc cgagcgggaa gccgagccgg    180

ccaaggaagc gcgcgtcgtg ggctcggagc ttgtggacac ttatacggtt tacatcatcc    240

aggtcactga tggcagccat gagtggacag taaagcaccg ctacagcgac ttccatgacc    300

tgcatgaaaa gctcgttgca gagagaaaga ttgataaaaa tctgcttccg cccaaaaaga    360

taattgggaa aaactcaaga agcttggtgg agaagaggga gaaggatctg gaggtctacc    420

tccagaagct cctggctgcc ttccctggcg tgacccccag agtactggcc cacttcttgc    480

attttcactt ctatgagata aatggcatca ccgcggcact ggctgaagag ctctttgaga    540

aaggagaaca gctcctgggg gccggcgagg tctttgccat tggacccctg cagctgtatg    600

ccgtcacgga gcagctgcag cagggaaagc ccacgtgcgc cagtggggat gccaagaccg    660

acctcgggca catcctggac ttcacctgtc gccttaagta ccttaaggtt tctggcacag    720

aaggaccttt tgggaccagc aacattcagg agcagctcct gccgttcgac ctatcaatat    780

tcaagtccct gcatcaggtg gagataagtc actgtgatgc taagcacatc agagggctgg    840

tcgcatcgaa gcccacctta gccacgctga gtgtccgctt ctcagcaacc tcgatgaagg    900

aagtccttgt tcctgaagcc tcagaatttg atgagtggga gcctgaaggc acaaccctag    960

aaggccctgt gactgccgtc atccccactt ggcaggcatt gaccacgctt gacctgagcc   1020

acaacagcat ctccgagatc gacgagtctg tgaaactgat cccaaagatt gagttcctgg   1080

acctgagtca caatggattg ctggttgtgg acaatctgca gcacctgtat aaccttgtgc   1140

atctggacct gtcctacaac aagctctcct ccttggaagg gcttcacacc aagctgggga   1200

acatcaagac cttaaacctg gcaggcaacc tcctagagag tctgagtggc ctgcacaagc   1260

tctactcact ggtcaacctg gatctccggg acaacaggat cgaacagatg gaggaggtcc   1320

ggagcatagg cagcctcccg tgtctggagc acgtgtctct gctgaacaac cctctgagca   1380

tcatccccga ctaccggacc aaggtgctgg ctcagttcgg agagagggcc tcagaggtct   1440

gtctggatga cacagtgacc acagagaagg agctggacac tgtggaagtg ctgaaagcaa   1500

ttcagaaagc caaggaggtc aagtccaaac tgagcaaccc agagaagaag ggtggtgaag   1560

actcccggct ctcagctgcc ccctgcatca gacccagcag ctcccctccc actgtggctc   1620

ccgcatctgc ctccctgccc cagcccatcc tctctaacca aggaatcatg ttcgttcagg   1680

aggaggccct ggccagcagc ctctcgtcca ctgacagtct gactcccgag caccagccca   1740

ttgcccaggg atgttctgat tccttggagt ccatccctgc gggacaggca gcttccgatg   1800

atttaaggga cgtgccagga gctgttggtg gtgcaagccc agaacatgcc gagccggagg   1860

tccaggtggt gccggggtct ggccagatca tcttcctgcc cttcacctgc attggctaca   1920

cggccaccaa tcaggacttc atccagcgcc tgagcacact gatccggcag gccatcgagc   1980

ggcagctgcc tgcctggatc gaggctgcca accagcggga ggagggccag ggtgaacagg   2040

gcgaggagga ggatgaggag gaggaagaag aggaggacgt ggctgagaac cgctactttg   2100

aaatggggcc cccagacgtg gaggaggagg agggaggagg ccagggggag gaagaggagg   2160

aggaagagga ggatgaagag gccgaggagg agcgcctggc tctggaatgg gccctgggcg   2220

cggacgagga cttcctgctg gagcacatcc gcatcctcaa ggtgctgtgg tgcttcctga   2280

tccatgtgca gggcagtatc cgccagttcg ccgcctgcct tgtgctcacc gacttcggca   2340

tcgcagtctt cgagatcccg caccaggagt ctcggggcag cagccagcac atcctctcct   2400

ccctgcgctt tgtcttttgc ttcccgcatg gcgacctcac cgagtttggc ttcctcatgc   2460

cggagctgtg tctggtgctc aaggtacggc acagtgagaa cacgctcttc attatctcgg   2520

acgccgccaa cctgcacgag ttccacgcgg acctgcgctc atgctttgca ccccagcaca   2580

tggccatgct gtgtagcccc atcctctacg gcagccacac cagcctgcag gagttcctgc   2640

gccagctgct caccttctac aaggtggctg gcggctgcca ggagcgcagc cagggctgct   2700

tccccgtcta cctggtctac agtgacaagc gcatggtgca gacggccgcc ggggactact   2760

caggcaacat cgagtgggcc agctgcacac tctgttcagc cgtgcggcgc tcctgctgcg   2820

cgccctctga ggccgtcaag tccgccgcca tcccctactg gctgttgctc acgccccagc   2880

acctcaacgt catcaaggcc gacttcaacc ccatgcccaa ccgtggcacc cacaactgtc   2940

gcaaccgcaa cagcttcaag ctcagccgtg tgccgctctc caccgtgctg ctggacccca   3000

cacgcagctg tacccagcct cggggcgcct ttgctgatgg ccacgtgcta gagctgctcg   3060

tggggtaccg ctttgtcact gccatcttcg tgctgcccca cgagaagttc cacttcctgc   3120

gcgtctacaa ccagctgcgg gcctcgctgc aggacctgaa gactgtggtc atcgccaaga   3180

cccccgggac gggaggcagc ccccagggct cctttgcgga tggccagcct gccgagcgca   3240

gggccagcaa tgaccagcgt ccccaggagg tcccagcaga ggctctggcc ccggccccag   3300

cggaagtccc agctccagcc cctgcagcag cctcagcctc aggcccagcg aagactccgg   3360

ccccagcaga ggcctcaact tcagctttgg tcccagagga gacgccagtg gaagctccag   3420

ccccaccccc agccgaggcc cctgcccagt acccgagtga gcacctcatc caggccacct   3480

cggaggagaa tcagatcccc tcgcacttgc ctgcctgccc gtcgctccgg cacgtcgcca   3540

gcctgcgggg cagcgccatc atcgagctct tccacagcag cattgctgag gttgaaaacg   3600

aggagctgag gcacctcatg tggtcctcgg tggtgttcta ccagacccca gggctggagg   3660

tgactgcctg cgtgctgctc tccaccaagg ctgtgtactt tgtgctccac gacggcctcc   3720

gccgctactt ctcagagcca ctgcaggatt tctggcatca gaaaaacacc gactacaaca   3780

acagcccttt ccacatctcc cagtgcttcg tgctaaagct tagtgacctg cagtcagtca   3840

atgtggggct tttcgaccag catttccggc tgacgggttc caccccgatg caggtggtca   3900

cgtgcttgac gcgggacagc tacctgacgc actgcttcct ccagcacctc atggtcgtgc   3960

tgtcctctct ggaacgcacg ccctcgccgg agcctgttga caaggacttc tactccgagt   4020

ttgggaacaa gaccacaggg aagatggaga actacgagct gatccactct agtcgcgtca   4080

agtttaccta ccccagtgag gaggagattg gggacctgac gttcactgtg gcccaaaaga   4140

tggctgagcc agagaaggcc ccagccctca gcatcctgct gtacgtgcag gccttccagg   4200

tgggcatgcc accccctggg tgctgcaggg gccccctgcg ccccaagaca ctcctgctca   4260

ccagctccga gatcttcctc ctggatgagg actgtgtcca ctacccactg cccgagtttg   4320

ccaaagagcc gccgcagaga gacaggtacc ggctggacga tggccgccgc gtccgggacc   4380

tggaccgagt gctcatgggc taccagacct acccgcaggc cctcaccctc gtcttcgatg   4440

acgtgcaagg tcatgacctc atgggcagtg tcaccctgga ccactttggg gaggtgccag   4500

gtggcccggc tagagccagc cagggccgtg aagtccagtg gcaggtgttt gtccccagtg   4560

ctgagagcag agagaagctc atctcgctgt tggctcgcca gtgggaggcc ctgtgtggcc   4620

gtgagctgcc tgtcgagctc accggctagc ccaggccaca gccagcctgt cgtgtccagc   4680

ctgacgccta ctggggcagg gcagcaggct tttgtgttct ctaaaaatgt tttatcctcc   4740

ctttggtacc ttaatttgac tgtcctcgca gagaatgtga acatgtgtgt gtgttgtgtt   4800

aattctttct catgttggga gtgagaatgc cgggcccctc agggctgtcg gtgtgctgtc   4860

agcctcccac aggtggtaca gccgtgcaca ccagtgtcgt gtctgctgtt gtgggaccgt   4920

tgttaacacg tgacactgtg ggtctgactt tctcttctac acgtcctttc ctgaagtgtc   4980

gagtccagtc ctttgttgct gttgctgttg ctgttgctgt tgctgttgct gttggcatct   5040

tgctgctaat cctgaggctg gtagcagaat gcacattgga agctcccacc ccatattgtt   5100

cttcaaagtg gaggtctccc ctgatccaga caagtgggag agcccgtggg ggcaggggac   5160

ctggagctgc cagcaccaag cgtgattcct gctgcctgta ttctctattc caataaagca   5220

gagtttgaca ccgtctgcaa aaaaaaaaaa aa                                 5252


<210>  835
<211>  2939
<212>  DNA
<213>  Human

<400>  835
cacgtgtctt agggtagcgc gcgcctgtct ctcttcgggt ctcgggccct tgggcgcagc     60

ggggcgcgcg ccatggcgaa ggcgaagaag gtcggggcgc gaaggaaggc ctccggggcg    120

ccggcgggag cgcgaggggg cccggcgaag gccaactcca atccgttcga ggtgaaagtt    180

aacaggcaga agttccagat cctgggccgg aagacgcgcc acgacgtggg actgcccggg    240

gtgtctcgcg cacgggccct caggaagcgt acacagactt tactaaaaga gtacaaagaa    300

agggataaat ccaatgtatt cagagataaa cgcttcggag aatacaacag caacatgagc    360

cccgaggaga agatgatgaa gaggtttgct ctggaacagc agcgacatca tgagaaaaaa    420

agcatctaca atctaaatga agatgaagaa ttgactcatt atggccagtc tttggcagac    480

atcgagaagc ataatgacat tgtggacagt gacagcgatg ctgaggatcg aggaacgttg    540

tctgctgagc tgactgctgc ccactttgga ggaggcggtg ggctccttca caagaagact    600

caacaggaag gcgaggagcg ggagaaaccg aagtcccgga aagagctgat tgaagagctc    660

attgccaagt caaaacaaga gaagagggag agacaagctc aacgagaaga tgccctcgag    720

ctcacggaga agctagacca agactggaaa gaaattcaga ctctcctgtc ccacaaaact    780

cccaagtcag agaacagaga caaaaaggaa aaacccaagc ccgatgcata tgacatgatg    840

gttcgcgagc ttggctttga aatgaaggcg cagccctcta acaggatgaa gacggaggca    900

gaattggcaa aggaagagca ggagcacctc aggaagctgg aggctgagag acttcgaaga    960

atgcttggaa aggatgagga tgaaaatgtt aagaaaccaa aacatatgtc agcagatgat   1020

ctgaatgatg gcttcgtgct agataaagat gacaggcgtt tgctttccta caaagatgga   1080

aagatgaatg tcgaggaaga tgtccaggaa gagcaaagca aggaagccag tgaccctgag   1140

agcaacgagg aagaaggtga cagttcaggc ggggaggaca cagaggagag cgacagccca   1200

gatagccact tggacctgga atccaacgtg gagagtgagg aagaaaacga gaagccagca   1260

aaagagcaga ggcagactcc tgggaaaggg ttgataagcg gcaaggaaag agctggaaaa   1320

gctaccagag acgagctgcc ctacacgttc gcagcccctg aatcctatga ggaactgaga   1380

tctctgttgt taggaagatc gatggaagag cagcttttgg tggtggagag aattcagaag   1440

tgcaaccacc cgagtctcgc agaaggaaac aaagcaaaat tagaaaaact gtttggcttt   1500

cttttggaat acgttggcga tttggctaca gatgacccac cagacctcac agtcattgat   1560

aagttggttg tgcacttata tcatctttgc cagatgtttc ctgaatctgc aagtgacgct   1620

atcaaatttg ttctccgaga tgcgatgcat gagatggaag aaatgattga gaccaaaggc   1680

cgggcggcat tgccagggtt ggatgtgctc atttatttga aaatcactgg gctgctattt   1740

ccaacttccg acttctggca cccagtggtg acccctgccc tcgtgtgcct cagtcagctg   1800

ctcaccaagt gccccatcct gtccctccag gacgtggtga agggcctgtt cgtgtgctgc   1860

ctgttcctgg agtatgtggc tttgtcccag aggtttatac ctgagcttat taattttctt   1920

cttgggattc tttacatagc aactccaaac aaagcaagcc aaggttccac tctggtgcac   1980

cctttcagag cgcttgggaa gaactcggaa ctgctcgtgg tgtctgctag agaggatgtg   2040

gccacgtggc agcagagcag cctctccctc cgctgggcga gtagactgag ggccccaact   2100

tcgacagagg ccaatcacat ccgactgtcc tgcctggctg tgggcctggc cctgctgaag   2160

cgctgcgtgc tcatgtacgg gtccctgcca tccttccacg ccatcatggg gcctctccaa   2220

gccctcctca cggatcacct ggcggactgc agccacccgc aggagctcca ggagctgtgt   2280

cagagcacac tgaccgaaat ggaaagccag aagcagctct gccggccgct gacctgtgag   2340

aagagcaagc ctgtcccact gaagcttttc acaccccggc tggtcaaagt cctcgagttt   2400

ggaagaaaac aaggcagtag taaggaggaa caggaaagga agaggctgat ccacaaacac   2460

aagcgtgaat ttaaaggggc cgttcgagaa atccgcaagg acaatcagtt cctggcgagg   2520

atgcaactct cagaaatcat ggaacgggat gcggaaagaa agcggaaagt aaagcagctt   2580

tttaacagcc tggctacaca ggaaggcgaa tggaaggctc tgaagaggaa aaagttcaaa   2640

aaataaatta cattttataa ataagctccc cccacccgct gcctgcggtt ttgtttctgt   2700

taaaacgtca cctgatgaaa tagaatgaat cctgaaatgc acctctggga tcgggaatgg   2760

tctgtgtgtt atcagctgcg actggttcac tgcgtctgga caagcctcat ggggactggg   2820

gattctggcc agtgtaattt ctgtcaacca cggacgtttg ccttcatgtg tagaatttac   2880

tgttgttatg caaattatat tttcaattat aaatgaaaaa aaaaaaaaaa aaaaaaaaa    2939


<210>  836
<211>  2939
<212>  DNA
<213>  Human

<400>  836
cacgtgtctt agggtagcgc gcgcctgtct ctcttcgggt ctcgggccct tgggcgcagc     60

ggggcgcgcg ccatggcgaa ggcgaagaag gtcggggcgc gaaggaaggc ctccggggcg    120

ccggcgggag cgcgaggggg cccggcgaag gccaactcca atccgttcga ggtgaaagtt    180

aacaggcaga agttccagat cctgggccgg aagacgcgcc acgacgtggg actgcccggg    240

gtgtctcgcg cacgggccct caggaagcgt acacagactt tactaaaaga gtacaaagaa    300

agggataaat ccaatgtatt cagagataaa cgcttcggag aatacaacag caacatgagc    360

cccgaggaga agatgatgaa gaggtttgct ctggaacagc agcgacatca tgagaaaaaa    420

agcatctaca atctaaatga agatgaagaa ttgactcatt atggccagtc tttggcagac    480

atcgagaagc ataatgacat tgtggacagt gacagcgatg ctgaggatcg aggaacgttg    540

tctgctgagc tgactgctgc ccactttgga ggaggcggtg ggctccttca caagaagact    600

caacaggaag gcgaggagcg ggagaaaccg aagtcccgga aagagctgat tgaagagctc    660

attgccaagt caaaacaaga gaagagggag agacaagctc aacgagaaga tgccctcgag    720

ctcacggaga agctagacca agactggaaa gaaattcaga ctctcctgtc ccacaaaact    780

cccaagtcag agaacagaga caaaaaggaa aaacccaagc ccgatgcata tgacatgatg    840

gttcgcgagc ttggctttga aatgaaggcg cagccctcta acaggatgaa gacggaggca    900

gaattggcaa aggaagagca ggagcacctc aggaagctgg aggctgagag acttcgaaga    960

atgcttggaa aggatgagga tgaaaatgtt aagaaaccaa aacatatgtc agcagatgat   1020

ctgaatgatg gcttcgtgct agataaagat gacaggcgtt tgctttccta caaagatgga   1080

aagatgaatg tcgaggaaga tgtccaggaa gagcaaagca aggaagccag tgaccctgag   1140

agcaacgagg aagaaggtga cagttcaggc ggggaggaca cagaggagag cgacagccca   1200

gatagccact tggacctgga atccaacgtg gagagtgagg aagaaaacga gaagccagca   1260

aaagagcaga ggcagactcc tgggaaaggg ttgataagcg gcaaggaaag agctggaaaa   1320

gctaccagag acgagctgcc ctacacgttc gcagcccctg aatcctatga ggaactgaga   1380

tctctgttgt taggaagatc gatggaagag cagcttttgg tggtggagag aattcagaag   1440

tgcaaccacc cgagtctcgc agaaggaaac aaagcaaaat tagaaaaact gtttggcttt   1500

cttttggaat acgttggcga tttggctaca gatgacccac cagacctcac agtcattgat   1560

aagttggttg tgcacttata tcatctttgc cagatgtttc ctgaatctgc aagtgacgct   1620

atcaaatttg ttctccgaga tgcgatgcat gagatggaag aaatgattga gaccaaaggc   1680

cgggcggcat tgccagggtt ggatgtgctc atttatttga aaatcactgg gctgctattt   1740

ccaacttccg acttctggca cccagtggtg acccctgccc tcgtgtgcct cagtcagctg   1800

ctcaccaagt gccccatcct gtccctccag gacgtggtga agggcctgtt cgtgtgctgc   1860

ctgttcctgg agtatgtggc tttgtcccag aggtttatac ctgagcttat taattttctt   1920

cttgggattc tttacatagc aactccaaac aaagcaagcc aaggttccac tctggtgcac   1980

cctttcagag cgcttgggaa gaactcggaa ctgctcgtgg tgtctgctag agaggatgtg   2040

gccacgtggc agcagagcag cctctccctc cgctgggcga gtagactgag ggccccaact   2100

tcgacagagg ccaatcacat ccgactgtcc tgcctggctg tgggcctggc cctgctgaag   2160

cgctgcgtgc tcatgtacgg gtccctgcca tccttccacg ccatcatggg gcctctccaa   2220

gccctcctca cggatcacct ggcggactgc agccacccgc aggagctcca ggagctgtgt   2280

cagagcacac tgaccgaaat ggaaagccag aagcagctct gccggccgct gacctgtgag   2340

aagagcaagc ctgtcccact gaagcttttc acaccccggc tggtcaaagt cctcgagttt   2400

ggaagaaaac aaggcagtag taaggaggaa caggaaagga agaggctgat ccacaaacac   2460

aagcgtgaat ttaaaggggc cgttcgagaa atccgcaagg acaatcagtt cctggcgagg   2520

atgcaactct cagaaatcat ggaacgggat gcggaaagaa agcggaaagt aaagcagctt   2580

tttaacagcc tggctacaca ggaaggcgaa tggaaggctc tgaagaggaa aaagttcaaa   2640

aaataaatta cattttataa ataagctccc cccacccgct gcctgcggtt ttgtttctgt   2700

taaaacgtca cctgatgaaa tagaatgaat cctgaaatgc acctctggga tcgggaatgg   2760

tctgtgtgtt atcagctgcg actggttcac tgcgtctgga caagcctcat ggggactggg   2820

gattctggcc agtgtaattt ctgtcaacca cggacgtttg ccttcatgtg tagaatttac   2880

tgttgttatg caaattatat tttcaattat aaatgaaaaa aaaaaaaaaa aaaaaaaaa    2939


<210>  837
<211>  5559
<212>  DNA
<213>  Human

<400>  837
ctatgaccaa atgtatgggg ctttttccca cacaccaagc aagcaagcag ttctgcagag     60

ggcacacagt gtcctctaac tcagtttgat tctgatacta tctacctgga aacagcatca    120

gatcccacag tttgagggct caatcccaca agactttccc ccatttcaga caccaatcac    180

aagtaatagt ttgtcaccta cacctctgac caagtggcta taaattggtg ttcccactac    240

cctctccttg gactcaactg atttgctaga gcaactgaca gaactcagga aaacacctac    300

atttactggt ttattttaaa ggatattata agggatacca atgaacacca gatggaagag    360

atgcataggg cagggtctgt gggaagggtg gcagagctcc catgccctcc caacgtgcac    420

caccctccag gaacctctaa atgttcagct gcccggcagc tccccacacc cagtcctttt    480

gagtttttaa tggaggcttt attatgtagg catgattgat tacatcattg gccactggtg    540

attagtttaa cttttagccc ctcatctcct ggaggttggg gcgtgggact gaaaaatcct    600

atcctctaat cataccttgg tctgtcctgt gagcagcccc catcccgaag cttccagggg    660

ttccccaacc actaatcatc taataagcat acaaaaaaca ctcttaccac tctggagatc    720

tcaagggttt ggggagctat atgtcaggaa acagggatga agaccaaaca tgtatttcac    780

tgtatcacac ctgttctcac ccctccccag atcttctctc aattaatatg agacaaaaaa    840

atgagtctga cttcttgacc aaaatatcag ttctgtcctt agcagcttta tggaggacag    900

atttagttta aattccttag gcattatgcc cctgtggctc cactcaatca gaaatagggt    960

caacggcaag gtcagggcct ccaatctggg caagagggag gcagccacgg tatccacaag   1020

tgtaattctc tgagtgctgg ttgctgggag gggcacaccc tgggccagca agtcacttgg   1080

ccaagggtgg ccaactgtga ggtagcactg ccctttactc cctaaaaaaa tgtgaatctc   1140

tttggagcaa actcctcttc agaaatttga gcacttgttt tctgagcaag ggaatcagct   1200

aatgcttttg actccccatc catcttcctg catcctcgtc ccacctctcc tgcccccact   1260

cacctggctc tgtctttacc cacaccatgg ttttggtaca agaacaccct tttccccata   1320

agctacattg gtccaggcca taaaaattca ttagttccct ttcttcaggg gccttctgaa   1380

atgctccctg gagaactctt tattcacttc tttgcacaag aatcacatat gtgtgaacac   1440

tggtattggc cttctaactc agtttcttca aaccagggtc ctggtctggt tgcccctgtc   1500

tcctcccact gagttttatc tccacataag tattgctcac caagaacaga gctgttgaca   1560

ccactgggcc tcaagcatgc tgaatgcatt gctgccaact gctctgcctt aagaaggttg   1620

gaaactgatg agggtgccac aaattgttca cctcagccct tctgggctgg ttggaggagg   1680

ccctctcatg aatcagtcag caaatgtttg acccctacca ggtggtcctg gtaatatgtg   1740

gtatgaatca tggtcctaga tgtctgccat agcaaataaa aaaggaagac agggaaagaa   1800

gctgtcgcct acagagtggc ttgatgacag ctgcctcact aatttaaaaa gccatgtgta   1860

gtgcttccta tttctcacta tgtttgggtg agtgggagag ggagaaagat tatatgggct   1920

tcgttgtgac actgttctta gccagtgggt caatagatga gttttggttt tgttttttag   1980

aagacaggat gagaagagag tgcccccttc cacctccaac atggcatgcc atgctaggtg   2040

ctgaaggagt tctctaagca gggatggagc accgtgcgtg tgtgtgtgta tatgtgcacg   2100

tgtgtgtgta cgtgtgtgtg tgtggcaggt ctagagggtc gatggctctt tcctgcctct   2160

tgcccttggt atgggtacct tagtgatgca tcatggccct cccttaggac acacagcttc   2220

gcagtgccag tgaacccact ccttttggct cctcctctgg aatgataagc ccagatgccc   2280

atgctgcccg tgaagggctt cttcttgaac tgaatgtgga gggcatctct ggtcccggcc   2340

atctgccagt gactctcatg tgcattcatg tccctctctt ctctctgtcc tgtcttctct   2400

gccgctgcct cttctctgca ggtacacttg ctgaaggacc agttggctgc tgaggctgcg   2460

gcgcggctgg aggcccaggc tcgcgtgcat cagcttttgc tgcagaacaa ggacatgctc   2520

cagcacatct ccctgctggt caagcaggtg caagagctgg aactgaagct gtcaggacag   2580

aacgccatgg gctcccagga cagcttgctg gagatcacct tccgctccgg agccctgccc   2640

gtgctctgtg accccacgac ccctaagcca gaggacctgc attcgccgcc gctgggcgcg   2700

ggcttggctg actttgccca ccctgcgggc agccccttag gtaggcgcga ctgcttggtg   2760

aagctggagt gctttcgctt tcttccgccc gaggacaccc cgcccccagc gcagggcgag   2820

gcgctcctgg gcggtctgga gctcatcaag ttccgagagt caggcatcgc ctcggagtac   2880

gagtccaaca cggacgagag cgaggagcgc gactcgtggt cccaggagga gctgccgcgc   2940

ctgctgaatg tcctgcagag gcaggaactg ggcgacggcc tggatgatga gatcgccgtg   3000

taggtgccga gggcgaggag atggaggcgg cggcgtggct ggaggggccg tgtctggctg   3060

ctgcccgggt aggggatgcc cagtgaatgt gcactgccga ggagaatgcc agccagggcc   3120

cgggagagtg tgaggtttca ggaaagtatt gagattctgc tttggagggt aaagtgggga   3180

agaaatcgga ttcccagagg tgaatcagct cctctcctac ttgtgactag agggtggtgg   3240

aggtaaggcc ttccagagcc catggcttca ggagagggtc tctctccagg actgccaggc   3300

tgctggagga cctgccccta cctgctgcat cgtcaggctc ccacgctttg tccgtgatgc   3360

ccccctaccc cctcactctc cccgtctcca tggtcccgac caggaaggga agccatcggt   3420

accttctcag gtactttgtt tctggatatc acgatgctgc gagttgccta accctccccc   3480

tacctttatg agaggaattc cttctccagg cccttgctga gattgtagag attgagtgct   3540

ctggaccgca aaagccaggc tagtccttgt agggtgagca tggaattgga atgtgtcaca   3600

gtggataagc ttttagagga actgaatcca aacattttct ccagccggac attgaatgtt   3660

gctacaaagg gagccttgaa gctttaacat ggttcaggcc cttggtgtga gagcccaggg   3720

ggaggacagc ttgtctgctg ctccaaatca cttagatctg attcctgttt tgaaagtcct   3780

gccctgcctt cctcctgcct gtagcccagc ccatctaaat ggaagctggg aattgcccct   3840

cacctcccct gtgtcctgtc cagctgaagc ttttgcagca ctttacctct ctgaaagccc   3900

cagaggacca gagcccccag ccttacctct caacctgtcc cctccactgg gcagtggtgg   3960

tcagttttta ctgcaaaaaa aaaaaaagaa aaaagagaaa gaaaaaaaag aatgaatgca   4020

agctgatagc tgagactgtg agactgtttt tgtccactct tctgaatcac tgccacttgg   4080

gtcagggacc acagccattg ccacccttgg cccatctctc tgcgtgcgtg ccttgagcac   4140

acatataaaa agtgccatgt gcaattgtct tatcttttat gatctaggct ttgcctaggg   4200

atcactactc cttaacgggc tggctggggc aatgaggaaa agctcctttg ctcctgtaag   4260

gccataagtg gctgttaaca gattttcaaa tgcctgaaga gattgctgag acctgctaga   4320

gtcatatgtt cggggaatta agtctttatc ctagacaaca aggtacagat gcaaactgca   4380

gtgttattgg agggtcaatc ggcaaggata tgattatccc aaaatggagt tcatcgaccc   4440

tagctttcct ttagattata tataaataaa agtgcagtcc tcttctaatg gccacagttg   4500

gttttcttgt agcccagaaa gtccaaatta aaggaaataa attcagtttt atgttagcct   4560

tccttggtgc atcagggtgt cagtggaaat aggatcaggt ggtgtgtgtg tgtgtgtttt   4620

gtgtgtgtgt gtacacatgt gtttatatat acatgtgtga gggaaagtgt gtacatatat   4680

gtaggattgt aaccagacgg aaaagaacga ggatctccag ggtgtttgaa tcagcaacag   4740

atttgtgttt tctaacatgc atttagttgg agaggcatgg ttctgtttgt tttgttttga   4800

tctaatttgc cattggaaat aggtacagtt acacagagaa ggaagaacca ggaaagtgag   4860

atccatgaaa ctaaatgagc agctgtcaga atccagtgtg gctgagccta cctagcttat   4920

gaaatctaac ccagggttcc ctgagtccaa gaccacttag attattaaga ttttgaacgt   4980

ccagaggagt gaaaagtctg ttttctgacg taagccggag ctgaggataa agccagaggc   5040

cagtggatta ggtgtatgga atgtggatgg agagggcttg tgtgggatgt ggccagggag   5100

tgggtgagga aggccgcttc taaatggcct gtaaaaactt gagattggat agacgaaagg   5160

aaatggagaa attaaagaat tggagaaact agttatctgt gttgctgact ttgggaccca   5220

tccaagactc ctgcccttgg ggtgttccat ggtggtttct tcctgcctgg gcgccaccct   5280

ttccccagtt caggccctcc ctggaggact agtttgtgta ttggtatcct ccccagtgga   5340

cccaaaccag cgcatacttg gtgtgtggag atgggagaca aaggacagat ctaggagcct   5400

tgaaggatca ccagccaccg accctccatc agggccaact gggcaggaaa gggaacattg   5460

cagacctgat ttcccgacga tgtcaccctg tcctccctcc ttgcttcttg ctctgctaac   5520

tcaactctgc cttcctcttt ttcattcttc tactctgcc                          5559


<210>  838
<211>  2212
<212>  DNA
<213>  Human

<400>  838
gccgcgaggg cggggcccgc agttcggttg cgctgcggag cgcagctgtg agggagtcgc     60

tgtgatccgg ggccccggaa cccgagctgg agctgaagcg caggctgcgg ggcgcggagt    120

cgggaggcct gagtgttcct tccagcatgt cggaggggga gtcccagaca gtacttagca    180

gtggctcaga cccaaaggta gaatcctcat cttcagctcc tggcctgaca tcagtgtcac    240

ctcctgtgac ctccacaacc tcagctgctt ccccagagga agaagaagaa agtgaagatg    300

agtctgagat tttggaagag tcgccctgtg ggcgctggca gaagaggcga gaagaggtga    360

atcaacggaa tgtaccaggt attgacagtg catacctggc catggataca gaggaaggtg    420

tagaggttgt gtggaatgag gtacagttct ctgaacgcaa gaactacaag ctgcaggagg    480

aaaaggttcg tgctgtgttt gataatctga ttcaattgga gcatcttaac attgttaagt    540

ttcacaaata ttgggctgac attaaagaga acaaggccag ggtcattttt atcacagaat    600

acatgtcatc tgggagtctg aagcaatttc tgaagaagac caaaaagaac cacaagacga    660

tgaatgaaaa ggcatggaag cgttggtgca cacaaatcct ctctgcccta agctacctgc    720

actcctgtga cccccccatc atccatggga acctgacctg tgacaccatc ttcatccagc    780

acaacggact catcaagatt ggctctgtgg ctcctgacac tatcaacaat catgtgaaga    840

cttgtcgaga agagcagaag aatctacact tctttgcacc agagtatgga gaagtcacta    900

atgtgacaac agcagtggac atctactcct ttggcatgtg tgcactggag atggcagtgc    960

tggagattca gggcaatgga gagtcctcat atgtgccaca ggaagccatc agcagtgcca   1020

tccagcttct agaagaccca ttacagaggg agttcattca aaagtgcctg cagtctgagc   1080

ctgctcgcag accaacagcc agagaacttc tgttccaccc agcattgttt gaagtgccct   1140

cgctcaaact ccttgcggcc cactgcattg tgggacacca acacatgatc ccagagaacg   1200

ctctagagga gatcaccaaa aacatggata ctagtgccgt actggctgaa atccctgcag   1260

gaccaggaag agaaccagtt cagactttgt actctcagtc accagctctg gaattagata   1320

aattccttga agatgtcagg aatgggatct atcctctgac agcctttggg ctgcctcggc   1380

cccagcagcc acagcaggag gaggtgacat cacctgtcgt gcccccctct gtcaagactc   1440

cgacacctga accagctgag gtggagactc gcaaggtggt gctgatgcag tgcaacattg   1500

agtcggtgga ggagggagtc aaacaccacc tgacacttct gctgaagttg gaggacaaac   1560

tgaaccggca cctgagctgt gacctgatgc caaatgagaa tatccccgag ttggcggctg   1620

agctggtgca gctgggcttc attagtgagg ctgaccagag ccggttgact tctctgctag   1680

aagagacctt gaacaagttc aattttgcca ggaacagtac cctcaactca gccgctgtca   1740

ccgtctcctc ttagagctca ctcgggccag gccctgatct gcgctgtggc tgtccctgga   1800

cgtgctgcag ccctcctgtc ccttcccccc agtcagtatt accctgtgaa gccccttccc   1860

tcctttatta ttcaggaggg ctgggggggc tccctggttc tgagcatcat cctttcccct   1920

cccctctctt cctcccctct gcactttgtt tacttgtttt gcacagacgt gggcctgggc   1980

cttctcagca gccgccttct agttgggggc tagtcgctga tctgccggct cccgcccagc   2040

ctgtgtggaa aggaggccca cgggcactag gggagccgaa ttctacaatc ccgctggggc   2100

ggccggggcg ggagagaaag gtggtgctgc agtggtggcc ctggggggcc attcgattcg   2160

cctcagttgc tgctgtaata aaagtctact ttttgctaaa aaaaaaaaaa aa           2212


<210>  839
<211>  4001
<212>  DNA
<213>  Human

<400>  839
aggcatcagc aatctatcag ggaacggcgg tggccggtgc ggcgtgttcg gtggcggctc     60

tggccgctca ggcgcctgcg gctgggtgag cgcacgcgag gcggcgaggc ggcagcgtgt    120

ttctaggtcg tggcgtcggg cttccggagc tttggcggca gctaggggag gatggcggag    180

tcttcggata agctctatcg agtcgagtac gccaagagcg ggcgcgcctc ttgcaagaaa    240

tgcagcgaga gcatccccaa ggactcgctc cggatggcca tcatggtgca gtcgcccatg    300

tttgatggaa aagtcccaca ctggtaccac ttctcctgct tctggaaggt gggccactcc    360

atccggcacc ctgacgttga ggtggatggg ttctctgagc ttcggtggga tgaccagcag    420

aaagtcaaga agacagcgga agctggagga gtgacaggca aaggccagga tggaattggt    480

agcaaggcag agaagactct gggtgacttt gcagcagagt atgccaagtc caacagaagt    540

acgtgcaagg ggtgtatgga gaagatagaa aagggccagg tgcgcctgtc caagaagatg    600

gtggacccgg agaagccaca gctaggcatg attgaccgct ggtaccatcc aggctgcttt    660

gtcaagaaca gggaggagct gggtttccgg cccgagtaca gtgcgagtca gctcaagggc    720

ttcagcctcc ttgctacaga ggataaagaa gccctgaaga agcagctccc aggagtcaag    780

agtgaaggaa agagaaaagg cgatgaggtg gatggagtgg atgaagtggc gaagaagaaa    840

tctaaaaaag aaaaagacaa ggatagtaag cttgaaaaag ccctaaaggc tcagaacgac    900

ctgatctgga acatcaagga cgagctaaag aaagtgtgtt caactaatga cctgaaggag    960

ctactcatct tcaacaagca gcaagtgcct tctggggagt cggcgatctt ggaccgagta   1020

gctgatggca tggtgttcgg tgccctcctt ccctgcgagg aatgctcggg tcagctggtc   1080

ttcaagagcg atgcctatta ctgcactggg gacgtcactg cctggaccaa gtgtatggtc   1140

aagacacaga cacccaaccg gaaggagtgg gtaaccccaa aggaattccg agaaatctct   1200

tacctcaaga aattgaaggt taaaaaacag gaccgtatat tccccccaga aaccagcgcc   1260

tccgtggcgg ccacgcctcc gccctccaca gcctcggctc ctgctgctgt gaactcctct   1320

gcttcagcag ataagccatt atccaacatg aagatcctga ctctcgggaa gctgtcccgg   1380

aacaaggatg aagtgaaggc catgattgag aaactcgggg ggaagttgac ggggacggcc   1440

aacaaggctt ccctgtgcat cagcaccaaa aaggaggtgg aaaagatgaa taagaagatg   1500

gaggaagtaa aggaagccaa catccgagtt gtgtctgagg acttcctcca ggacgtctcc   1560

gcctccacca agagccttca ggagttgttc ttagcgcaca tcttgtcccc ttggggggca   1620

gaggtgaagg cagagcctgt tgaagttgtg gccccaagag ggaagtcagg ggctgcgctc   1680

tccaaaaaaa gcaagggcca ggtcaaggag gaaggtatca acaaatctga aaagagaatg   1740

aaattaactc ttaaaggagg agcagctgtg gatcctgatt ctggactgga acactctgcg   1800

catgtcctgg agaaaggtgg gaaggtcttc agtgccaccc ttggcctggt ggacatcgtt   1860

aaaggaacca actcctacta caagctgcag cttctggagg acgacaagga aaacaggtat   1920

tggatattca ggtcctgggg ccgtgtgggt acggtgatcg gtagcaacaa actggaacag   1980

atgccgtcca aggaggatgc cattgagcac ttcatgaaat tatatgaaga aaaaaccggg   2040

aacgcttggc actccaaaaa tttcacgaag tatcccaaaa agttctaccc cctggagatt   2100

gactatggcc aggatgaaga ggcagtgaag aagctgacag taaatcctgg caccaagtcc   2160

aagctcccca agccagttca ggacctcatc aagatgatct ttgatgtgga aagtatgaag   2220

aaagccatgg tggagtatga gatcgacctt cagaagatgc ccttggggaa gctgagcaaa   2280

aggcagatcc aggccgcata ctccatcctc agtgaggtcc agcaggcggt gtctcagggc   2340

agcagcgact ctcagatcct ggatctctca aatcgctttt acaccctgat cccccacgac   2400

tttgggatga agaagcctcc gctcctgaac aatgcagaca gtgtgcaggc caaggtggaa   2460

atgcttgaca acctgctgga catcgaggtg gcctacagtc tgctcagggg agggtctgat   2520

gatagcagca aggatcccat cgatgtcaac tatgagaagc tcaaaactga cattaaggtg   2580

gttgacagag attctgaaga agccgagatc atcaggaagt atgttaagaa cactcatgca   2640

accacacaca atgcgtatga cttggaagtc atcgatatct ttaagataga gcgtgaaggc   2700

gaatgccagc gttacaagcc ctttaagcag cttcataacc gaagattgct gtggcacggg   2760

tccaggacca ccaactttgc tgggatcctg tcccagggtc ttcggatagc cccgcctgaa   2820

gcgcccgtga caggctacat gtttggtaaa gggatctatt tcgctgacat ggtctccaag   2880

agtgccaact actgccatac gtctcaggga gacccaatag gcttaatcct gttgggagaa   2940

gttgcccttg gaaacatgta tgaactgaag cacgcttcac atatcagcaa gttacccaag   3000

ggcaagcaca gtgtcaaagg tttgggcaaa actacccctg atccttcagc taacattagt   3060

ctggatggtg tagacgttcc tcttgggacc gggatttcat ctggtgtgaa tgacacctct   3120

ctactatata acgagtacat tgtctatgat attgctcagg taaatctgaa gtatctgctg   3180

aaactgaaat tcaattttaa gacctccctg tggtaattgg gagaggtagc cgagtcacac   3240

ccggtggctc tggtatgaat tcacccgaag cgcttctgca ccaactcacc tggccgctaa   3300

gttgctgatg ggtagtacct gtactaaacc acctcagaaa ggattttaca gaaacgtgtt   3360

aaaggttttc tctaacttct caagtccctt gttttgtgtt gtgtctgtgg ggaggggttg   3420

ttttggggtt gtttttgttt tttcttgcca ggtagataaa actgacatag agaaaaggct   3480

ggagagagat tctgttgcat agactagtcc tatggaaaaa accaagcttc gttagaatgt   3540

ctgccttact ggtttcccca gggaaggaaa aatacacttc cacccttttt tctaagtgtt   3600

cgtctttagt tttgattttg gaaagatgtt aagcatttat ttttagttaa aaataaaaac   3660

taatttcata ctatttagat tttctttttt atcttgcact tattgtcccc tttttagttt   3720

tttttgtttg cctcttgtgg tgaggggtgt gggaagacca aaggaaggaa cgctaacaat   3780

ttctcatact tagaaacaaa aagagctttc cttctccagg aatactgaac atgggagctc   3840

ttgaaatatg tagtattaaa agttgcattt gaaattcttg actttcttat gggcactttt   3900

gtcttccaaa ttaaaactct accacaaata tacttaccca agggctaata gtaatactcg   3960

attaaaaatg cagatgcctt ctctaaaaaa aaaaaaaaaa a                       4001


<210>  840
<211>  3959
<212>  DNA
<213>  Human

<400>  840
ttacaggaac agtgtggcct ctctggaact ctgcagacca actgccgtga tgctgaagtt     60

ccgaacagtc catgggggcc tgaggctcct gggaatccgc cgaacctcca ccgcccccgc    120

tgcctcccca aatgtccggc gcctggagta taagcccatc aagaaagtca tggtggccaa    180

cagaggtgag attgccatcc gtgtgttccg ggcctgcacg gagctgggca tccgcaccgt    240

agccatctac tctgagcagg acacgggcca gatgcaccgg cagaaagcag atgaagccta    300

tctcatcggc cgcggcctgg cccccgtgca ggcctacctg cacatcccag acatcatcaa    360

ggtggccaag gagaacaacg tagatgcagt gcaccctggc tacgggttcc tctctgagcg    420

agcggacttc gcccaggcct gccaggatgc aggggtccgg tttattgggc caagcccaga    480

agtggtccgc aagatgggag acaaggtgga ggcccgggcc atcgccattg ctgcgggtgt    540

tcccgttgtc cctggcacag atgcccccat cacgtccctg catgaggccc acgagttctc    600

caacacctac ggcttcccca tcatcttcaa ggcggcctat gggggtggag ggcgtggcat    660

gagggtggtg cacagctacg aggagctgga ggagaattac acccgggcct actcagaggc    720

tctggccgcc tttgggaatg gggcgctgtt tgtggagaag ttcatcgaga agccacggca    780

catcgaggtg cagatcttgg gggaccagta tgggaacatc ctgcacctgt acgagcgaga    840

ctgctccatc cagcggcggc accagaaggt ggtcgagatt gcccccgccg cccacctgga    900

cccgcagctt cggactcggc tcaccagcga ctctgtgaaa ctcgctaaac aggtgggcta    960

cgagaacgca ggcaccgtgg agttcctggt ggacaggcac ggcaagcact acttcatcga   1020

ggtcaactcc cgcctgcagg tggagcacac ggtcacagag gagatcaccg acgtagacct   1080

ggtccatgct cagatccacg tggctgaggg caggagccta cccgacctgg gcctgcggca   1140

ggagaacatc cgcatcaacg ggtgtgccat ccagtgccgg gtcaccaccg aggaccccgc   1200

gcgcagcttc cagccggaca ccggccgcat tgaggtgttc cggagcggag agggcatggg   1260

catccgcctg gataatgctt ccgccttcca aggagccgtc atctcgcccc actacgactc   1320

cctgctggtc aaagtcattg cccacggcaa agaccacccc acggccgcca ccaagatgag   1380

cagggccctt gcggagttcc gcgtccgagg tgtgaagacc aacatcgcct tcctgcagaa   1440

tgtgctcaac aaccagcagt tcctggcagg cactgtggac acccagttca tcgacgagaa   1500

cccagagctg ttccagctgc ggcctgcaca gaaccgggcc caaaagctgt tgcactacct   1560

cggccatgtc atggtaaacg gtccaaccac cccgattccc gtcaaggcca gccccagccc   1620

cacggacccc gttgtccctg cagtgcccat aggcccgccc ccggctggtt tcagagacat   1680

cctgctgcga gaggggcctg agggctttgc tcgagctgtg cggaaccacc cggggctgct   1740

gctgatggac acgaccttca gggacgccca ccagtcactg ctggccactc gtgtgcgcac   1800

ccacgatctc aaaaagatcg ccccctatgt tgcccacaac ttcagcaagc tcttcagcat   1860

ggagaactgg ggaggagcca cgtttgacgt cgccatgcgc ttcctgtatg agtgcccctg   1920

gcggcggctg caggagctcc gggagctcat ccccaacatc cctttccaga tgctgctgcg   1980

gggggccaat gctgtgggct acaccaacta cccagacaac gtggtcttca agttctgtga   2040

agtggccaaa gagaatggca tggatgtctt ccgtgtgttt gactccctca actacttgcc   2100

caacatgctg ctgggcatgg aggcggcagg aagtgccgga ggcgtggtgg aggctgccat   2160

ctcatacacg ggcgacgtgg ccgaccccag ccgcaccaag tactcactgc agtactacat   2220

gggcttggcc gaagagctgg tgcgagctgg cacccacatc ctgtgcatca aggacatggc   2280

cgggctgctg aagcccacgg cctgcaccat gctggtcagc tccctccggg accgcttccc   2340

cgacctccca ctgcacatcc acacccacga cacgtcaggg gcaggcgtgg cagccatgct   2400

ggcctgtgcc caggctggag ctgatgtggt ggatgtggca gctgattcca tgtctgggat   2460

gacttcacag cccagcatgg gggccctggt ggcctgtacc agagggactc ccctggacac   2520

agaggtgccc atggagcgcg tgtttgacta cagtgagtac tgggaggggg ctcggggact   2580

gtacgcggcc ttcgactgca cggccaccat gaagtctggc aactcggacg tgtatgaaaa   2640

tgagatccca gggggccagt acaccaacct gcacttccag gcccacagca tggggcttgg   2700

ctccaagttc aaggaggtca agaaggccta tgtggaggcc aaccagatgc tgggcgatct   2760

catcaaggtg acgccctcct ccaagatcgt gggggacctg gcccagttta tggtgcagaa   2820

tggattgagc cgggcagagg ccgaagctca ggcggaagag ctgtcctttc cccgctccgt   2880

ggtggagttc ctgcagggct acatcggtgt cccccatggg gggttccccg aaccctttcg   2940

ctctaaggta ctgaaggacc tgccaagggt ggaggggcgg cctggagcct ccctccctcc   3000

cctggatctg caggcactgg agaaggagct ggtagaccgg catggggagg aggtgacgcc   3060

ggaagatgtg ctctcagcag ctatgtaccc cgatgtgttt gcccacttca aggacttcac   3120

tgccaccttt ggccccctgg atagcctgaa tactcgcctc ttcctgcagg gacccaagat   3180

cgcagaggag tttgaggtgg agctggagcg gggcaagacg ctgcacatca aagccctggc   3240

cgtgagcgac ctgaaccggg ccggccagag gcaggtcttc tttgagctca atgggcagct   3300

gcggtccatc ttggtcaagg acacccaggc catgaaggag atgcacttcc accccaaggc   3360

cctaaaggac gtgaagggcc agatcggggc gcccatgcct gggaaggtga tagacatcaa   3420

agtggtggca ggggccaagg tggccaaggg ccagcccctg tgtgtgctca gtgccatgaa   3480

gatggagact gtggtgacct cacccatgga gggtactgtc cgcaaggttc atgtgaccaa   3540

ggacatgaca ctggaaggtg acgacctcat cctggagatc gagtgatctt gccccagacc   3600

ggcagcctgg ccatccccaa gccttcaaca gaagctgtgc tgccacggca ggcccaggcc   3660

agccagtgcc cgaggccagg aaggccgggc cgtggaggtc ctgtccacag ctggacagga   3720

gagacaccgc ctgcggtggt tcattccttt cagccatcgt cctttcctcc ggcggacagc   3780

tgcttacatg ttcatctctt gccaaataag ggtcccctcc tcactggaga ctacaagtgg   3840

tgggtcaggt ggtcctagga cccaggggag gtttaggggt cctatctcct gggggaaggg   3900

gagatctaag atgtcccagg tcctgggaag tttactcaat aaagctggct ttcccctgc    3959


<210>  841
<211>  4161
<212>  DNA
<213>  Human

<400>  841
gcgcgcgggc ggcgtagccg gcctgtctgg gccgcctcgt ggggagggag ggggcgcccg     60

gccgcccggc ggcgaccccg gggcctggcc gccaccatgg gcttcgagct ggaccgcttc    120

gacggcgacg tggacccgga cctgaagtgc gcgctgtgcc acaaggtcct ggaggacccg    180

ctgaccacgc cgtgcggcca cgtcttctgc gccggctgcg tgctgccctg ggtggtgcag    240

gagggcagct gcccggcgcg ctgccgcggt cgcctgtcgg ccaaagagct caaccacgtc    300

ctgccgctca agcgccttat cctcaagctg gacatcaagt gcgcgtacgc gacgcgcggc    360

tgcggccggg tggtcaagct gcagcagctg ccggagcacc tcgagcgctg cgacttcgcg    420

cccgcgcgct gtcgccacgc gggttgcggc caggtgctgc tgcggcgcga cgtggaggcg    480

cacatgcgcg acgcgtgcga cgcgcggcca gtgggccgct gccaggaggg ctgcgggcta    540

cccttgacgc acggcgagca gcgcgcgggc ggccactgct gcgcgcgagc gctgcgggcg    600

cacaacggcg cgctccaggc ccgcctgggc gcgctgcaca aggcgctcaa gaaggaggcg    660

ctgcgcgctg ggaagcgcga gaagtcgctg gtggcccagc tggccgcggc gcagcttgag    720

ctgcagatga ccgcgctgcg ctaccagaag aaattcaccg aatacagcgc gcgcctcgac    780

tcgctcagcc gctgcgtggc cgcgccgccc ggcggcaagg gcgaagaaac caaaagtctg    840

actcttgtcc tgcatcggga ctccggctcc ctgggattca atattattgg tggccggccg    900

agtgtggata accacgatgg atcatccagt gaaggaatct ttgtatccaa gatagttgac    960

agtgggcctg cagccaagga aggaggcctg caaattcatg acaggattat tgaggtcaac   1020

ggcagagact tatccagagc aactcatgac caggctgtgg aagctttcaa gacagccaag   1080

gagcccatag tggtgcaggt gttgagaaga acaccaagga ccaaaatgtt cacgcctcca   1140

tcagagtctc agctggtgga cacgggaacc caaaccgaca tcacctttga acatatcatg   1200

gccctcacta agatgtcctc tcccagccca cccgtgctgg atccctatct cttgccagag   1260

gagcatccct cagcccatga atactacgat ccaaatgact acattggaga catccatcag   1320

gagatggaca gggaggagct ggagctggag gaagtggacc tctacagaat gaacagccag   1380

gacaagctgg gcctcactgt gtgctaccgg acggacgatg aagacgacat tgggatttat   1440

atcagtgaga ttgaccctaa cagcattgca gccaaggatg ggcgcatccg agaaggagac   1500

cgcattatcc agattaatgg gatagaggtg cagaaccgtg aagaggctgt ggctcttcta   1560

accagtgaag aaaataaaaa cttttcattg ctgattgcaa ggcctgaact ccagctggat   1620

gagggctgga tggatgatga caggaacgac tttctggatg acctgcacat ggacatgctg   1680

gaggagcagc accaccaggc catgcaattc acagctagcg tgctgcagca gaagaagcac   1740

gacgaagacg gtgggaccac agatacagcc accatcttgt ccaaccagca cgagaaggac   1800

agcggtgtgg ggcggaccga cgagagcacc cgtaatgacg agagctcgga gcaagagaac   1860

aatggcgacg acgccaccgc atcctccaac ccgctggcgg ggcagaggaa gctcacctgc   1920

agccaggaca ccttgggcag cggcgacctg cccttcagca acgagtcttt catttcggcc   1980

gactgcacgg acgccgacta cctggggatc ccggtggacg agtgcgagcg cttccgcgag   2040

ctcctggagc tcaagtgcca ggtgaagagc gccacccctt acggcctgta ctaccctagc   2100

ggccccctgg acgccggcaa gagtgaccct gagagcgtgg acaaggagct ggagctgctg   2160

aacgaagagc tgcgcagcat cgagctggag tgcctgagca tcgtgcgcgc ccacaagatg   2220

cagcagctca aggagcagta ccgcgagtcc tggatgctgc acaacagcgg cttccgcaac   2280

tacaacacca gcatcgacgt gcgcagacac gagctctcag atatcaccga gctcccggag   2340

aaatccgaca aggacagctc gagcgcctac aacacaggcg agagctgccg cagcaccccg   2400

ctcaccctgg agatctcccc cgacaactcc ttgaggagag cggcggaggg catcagctgc   2460

ccgagcagcg aaggggctgt ggggaccacg gaagcctacg ggccagcctc caagaatctg   2520

ctctccatca cggaagatcc cgaagtgggc acccctacct atagcccgtc cctgaaggag   2580

ctggacccca accagcccct ggaaagcaaa gagcggagag ccagcgacgg gagccggagc   2640

cccacgccca gccagaagct gggcagcgcc tacctgccct cctatcacca ctccccatac   2700

aagcacgcgc acatcccggc gcacgcccag cactaccaga gctacatgca gctgatccag   2760

cagaagtcgg ccgtggagta cgcgcaaagc cagatgagcc tggtgagcat gtgcaaggac   2820

ctgagctctc ccaccccgtc ggagccgcgc atggagtgga aggtgaagat ccgcagcgac   2880

gggacgcgct acatcaccaa gaggcccgtg cgggaccgcc tgctgcggga gcgcgccctg   2940

aagatccggg aagagcgcag cggcatgacc accgacgacg acgcggtgag cgagatgaag   3000

atggggcgct actggagcaa ggaggagagg aagcagcacc tggtgaaggc caaggagcag   3060

cggcggcggc gcgagttcat gatgcagagc aggttggatt gtctcaagga gcagcaagca   3120

gccgatgaca ggaaggagat gaacattctc gaactgagcc acaaaaagat gatgaagaag   3180

aggaataaga aaatcttcga taactggatg acgatccaag aactcttaac ccacggcaca   3240

aaatccccgg acggcactag agtatacaat tccttcctat cggtgactac tgtataattt   3300

tcacttctgc attatgtaca taaaggagac cactaccact ggggtagaaa ttcctgcctc   3360

gttcaatgcg gcaagttttt gtatataaga taagtacggt cttcatgttt atagtccaaa   3420

tttgcaaacc ctacaactct gggtgtcata ggtctatttt aagggaagag agagaaaaac   3480

acccttacta tcttggaagg caatattaac aaacagagct tttttcaaat agcaattgta   3540

cttttctacc tgtacccttt tacataaagt gtttaaattt cagaaagatc ttttattaag   3600

catactttca cagaataact tgtttaaact atattcatat aaaaaagtta aacacgcttt   3660

ttttcctgcc taaaacacaa atacaactgc cagtatgtat ttttaatgga accctatttt   3720

ataatggtac gttactgaat gtgtttcata tgcgtgaccg ttaagatatt atcatttagg   3780

tgaaggtttc aactcaaaac cacccaaccc ggtggttaac gatttaatac atataaccaa   3840

accggcagcg tttagagttg ggatatacat ttaaacattt tcctggttaa ggttcccaag   3900

agagtgtaaa ggttttagca gaaagcaaaa tatcttgcat ctttatggaa gtttaaagca   3960

tgtttgcaaa tattgcagcc cattgaaaga atttgcatgt acaggaaagt tgtggatgga   4020

gacggtttgt ggaattttaa gtgctcattg tagtaaactt ttgctttgta gatttgaagg   4080

tacagactta tacaggcaag ttcacaaaat catgattagt tacaaacagt aaaatgaagt   4140

taaaataaat tattattttc t                                             4161


<210>  842
<211>  2474
<212>  DNA
<213>  Human

<400>  842
gacatcaccg gccagccggg tggagtgagc ggcgctgggc tcgggctccg gctccgcggg     60

cggaagaggc ggcggcggcg gcagaagcgg cggcggcggc ggcgggagcc gaggaggagg    120

ttccggacgc tgcttaggaa ccggggactc aggagtgccc gcgccctgag cgctcagctc    180

cagaggcgtc atggctgagt acgggaccct cctgcaagac ctgaccaaca acatcaccct    240

tgaagatcta gaacagctca agtcggcctg caaggaagac atccccagcg aaaagagtga    300

ggagatcact actggcagtg cctggtttag cttcctggag agccacaaca agctggacaa    360

agacaacctc tcctacattg agcacatctt tgagatctcc cgccgtcctg acctactcac    420

tatggtggtt gactacagaa cccgtgtgct gaagatctct gaggaggatg agctggacac    480

caagctaacc cgtatcccca gtgccaagaa gtacaaagac attatccggc agccctctga    540

ggaagagatc atcaaattgg ctcccccacc gaagaaggcc tgagcaaggg ggaggaagag    600

gaggaaggtt ggaccttcat cagaccactc ccttccccca tcctccagga gagggggcaa    660

gggcaaccca ccatctaccc acttactaac ctggtcctaa cccccttact gtgcgcgtgt    720

gtgtgcgtgt gcgcacgctc tggctgtttg tctatatgtc tagctcatct agttcctctt    780

cttaagggga tgggggtcag gggctagggg agggggctga gtttccccac tttaggagga    840

ggtgggggct atttctatgc aaatagaaat cagcacattc ctcctacttc cctttcctcc    900

actcccccca tatctttaaa gtgtggaagc agaaaggacc tgcattttcc tacattgagg    960

agctgacata ggggtaaggt atgggagagg taggtggatc cagggaaaag cagtggggac   1020

ggaaggcaaa gagaccactc aacccccacc tggaaggggc aaagaaaagc cagagttcca   1080

tgtttgtact cctgtgctgg actgtttcct gagtaccagc aggtcccttt ttgtctctca   1140

tgggcctagc ataggtatga gccagggatc ctttcctggt ccctaagatc aaaccccatg   1200

gagcagccag cgttagatgc ccccacccac ctgtactctg gagagactgt gctgggaaca   1260

tgtaccactg agcctgagat ggggatgagg gcagagagag gggagccccc tcttccactc   1320

agttgttcct actcagactg ttgcactcta aacctaggga ggttgaagaa tgagaccctt   1380

aggttttaac acgaatcctg acaccaccat ctatagggtc ccaacttggt tattgtaggc   1440

aaccttccct ctctccttgg tgaagaacat cccaagccag aaagaagtta actacagtgt   1500

tttcctttgc accgatcccc accccaattc aatcccggaa gggacttact taggaaaccc   1560

ttctttacta gatatcctgg ccccctgggc ttgtgaacac ctcctagcca catcactaca   1620

gtacagtgag tgaccccagc ctcctgccta ccccaagatg cccctcccca ccctgaccgt   1680

gctaactgtg tgtacatata tattctacat atatgtatat taaaactgca ctgccatgtc   1740

tgcccttttt tgtggtgtct agcattaact tattgtctag gccagagcgg gggtgggagg   1800

ggaatgccac agtgaaggga gtggcagaat caaattgcta catagtccaa acaaaaaaga   1860

aggctttttc aaaaaacatt aaattcacat gcagtctcag agactattta gacaaagttc   1920

aagttaggag cttttaggat gtgggagtaa aactttaatg ggaggggagg gctggctgct   1980

ggaagaagga agaagccaga ctggttagac agtactctta actcctagcc cagcctagcg   2040

tgccctgccc ctctggccac tgctgcagac acctgcctta acacacacac ctctaggact   2100

ccacagtttt gccttaaagg accttcccaa gtctcccttt ccctgtctgg cttctccctt   2160

aagaagagag agatacttgt agaattgggt ggggggaatg agcatgaact gtccttccat   2220

ttgggatatg ttacattaga gtgagagaga gaataaggag cctttcttat ggaagaaatg   2280

ggagaagaga gacagggttc ttttcagcag agtctagtag tttctctgta aggcaaaata   2340

atctaaaaag actaacctgc ccacccactc cttatattgc tgtgagattg cccctatctt   2400

gtgctcttct gtctgcagtg tgcacggcct tgttctaacc cggaataaag gtgattgatt   2460

gtattgcaaa aaaa                                                     2474


<210>  843
<211>  4717
<212>  DNA
<213>  Human

<400>  843
attatgcaac ccgcctcccc gcccgcccgg tggagcttcc actcggctgc gggctggagc     60

ggcggcgggc aggcgtgcgg aggacactcc tgcgaccagg tactggctgt gatcgaactt    120

ctcaaccctc agagacttag atcttccacc tcactccctc agccaagcct ccaggccccc    180

tcgtgcatcc gtggtggcct ctctgccttc tctgttctgt tctccccatg gcccagacat    240

gagtggcccc ctagaagggg ctgatggggg aggggacccc aggcctgggg aatcattttg    300

tcctgggggc gtcccatccc ctgggccccc acagcaccgg ccttgcccag gccccagcct    360

ggccgatgac accgatgcca acagcaatgg ttcaagtggc aatgagtcca acgggcatga    420

gtctagaggc gcatctcagc ggagctcaca cagctcctcc tcaggcaacg gcaaggactc    480

agccctgctg gagaccactg agagcagcaa gagcacaaac tctcagagcc catccccacc    540

cagcagttcc attgcctaca gcctcctgag tgccagctca gagcaggaca acccgtccac    600

cagtggctgc agcagtgaac agtcagcccg ggcaaggact cagaaggaac tcatgacagc    660

acttcgagag ctcaagcttc gactgccgcc agagcgccgg ggcaagggcc gctctgggac    720

cctggccacg ctgcagtacg cactggcctg tgtcaagcag gtgcaggcca accaggaata    780

ctaccagcag tggagcctgg aggagggcga gccttgctcc atggacatgt ccacctatac    840

cctggaggag ctggagcaca tcacgtctga gtacacactt cagaaccagg ataccttctc    900

agtggctgtc tccttcctga cgggccgaat cgtctacatt tcggagcagg cagccgtcct    960

gctgcgttgc aagcgggacg tgttccgggg tacccgcttc tctgagctcc tggctcccca   1020

ggatgtggga gtcttctatg gttccactgc tccatctcgc ctgcccacct ggggcacagg   1080

ggcctcagca ggttcaggcc tcagggactt tacccaggag aagtccgtct tctgccgtat   1140

cagaggaggt cctgaccggg atccagggcc tcggtaccag ccattccgcc taaccccgta   1200

tgtgaccaag atccgggtct cagatggggc ccctgcacag ccgtgctgcc tgctgattgc   1260

agagcgcatc cattcgggtt acgaagctcc ccggataccc cctgacaaga ggattttcac   1320

tacgcggcac acacccagct gcctcttcca ggatgtggat gaaagggctg cccccctgct   1380

gggctacctg ccccaggacc tcctgggggc cccagtgctc ctgttcctgc atcctgagga   1440

ccgacccctc atgctggcta tccacaagaa gattctgcag ttggcgggcc agccctttga   1500

ccactcccct atccgcttct gtgcccgcaa cggggagtat gtcaccatgg acaccagctg   1560

ggctggcttt gtgcacccct ggagccgcaa ggtagccttc gtgttgggcc gccacaaagt   1620

acgcacggcc cccctgaatg aggacgtgtt cactcccccg gcccccagcc cagctccctc   1680

cctggacact gatatccagg agctgtcaga gcagatccac cggctgctgc tgcagcccgt   1740

ccacagcccc agccccacgg gactctgtgg agtcggcgcc gtgacatccc caggccctct   1800

ccacagccct gggtcctcca gtgatagcaa cgggggtgat gcagaggggc ctgggcctcc   1860

tgcgccagtg actttccagc agatctgtaa ggatgtgcat ctggtgaagc accagggcca   1920

gcagcttttt attgagtctc gggcccggcc tcagtcccgg ccccgcctcc ctgctacagg   1980

cacgttcaag gccaaggccc ttccctgcca atccccagac ccagagctgg aggcgggttc   2040

tgctcccgtc caggccccac tagccttggt ccctgaggag gccgagagga aagaagcctc   2100

cagctgctcc taccagcaga tcaactgcct ggacagcatc ctcaggtacc tggagagctg   2160

caacctcccc agcaccacta agcgtaaatg tgcctcctcc tcctcctata ccacctcctc   2220

agcctctgac gacgacaggc agaggacagg tccagtctct gtggggacca agaaagatcc   2280

gccgtcagca gcgctgtctg gggagggggc caccccacgg aaggagccag tggtgggagg   2340

caccctgagc ccgctcgccc tggccaataa ggcggagagt gtggtgtccg tcaccagtca   2400

gtgtagcttc agctccacca tcgtccatgt gggagacaag aagcccccgg agtcggacat   2460

catcatgatg gaggacctgc ctggcctagc cccaggccca gcccccagcc cagcccccag   2520

ccccacagta gcccctgacc cagccccaga cgcctaccgt ccagtggggc tgaccaaggc   2580

cgtgctgtcc ctgcacacac agaaggaaga gcaagccttc ctcagccgct tccgagacct   2640

gggcaggctg cgtggactcg acagctcttc cacagctccc tcagcccttg gcgagcgagg   2700

ctgccaccac ggccccgcac ccccaagccg ccgacaccac tgccgatcca aagccaagcg   2760

ctcacgccac caccagaacc ctcgggctga agcgccctgc tatgtctcac acccctcacc   2820

cgtgccaccc tccaccccct ggcccacccc accagccact acccccttcc cagcggttgt   2880

ccagccctac cctctcccag tgttctctcc tcgaggaggc ccccagcctc ttccccctgc   2940

tcccacatct gtgcccccag ctgctttccc cgcccctttg gtgaccccaa tggtggcctt   3000

ggtgctccct aactatctgt tcccaacccc atccagctat ccttatgggg cactccagac   3060

ccctgctgaa gggcctccca ctcctgcctc gcactcccct tctccatcct tgcccgccct   3120

cgccccgagt cctcctcacc gcccggactc tccactgttc aactcgagat gcagctctcc   3180

actccagctc aatctgctgc agctggagga gctcccccgt gctgaggggg ctgctgttgc   3240

aggaggccct gggagcagtg ccgggccccc acctcccagt gcggaggctg ctgagccaga   3300

ggccagactg gcggaggtca ctgagtcctc caatcaggac gcactttccg gctccagtga   3360

cctgctcgaa cttctgctgc aagaggactc gcgctccggc acaggctccg cagcctcggg   3420

ctccttgggc tctggcttgg gctctgggtc tggttcaggc tcccatgaag ggggcagcac   3480

ctcagccagc atcactcgca gcagccagag cagccacaca agcaaatact ttggcagcat   3540

cgactcttcc gaggctgagg ctggggctgc tcggggcggg gctgagcctg gggaccaggt   3600

gattaagtac gtgctccagg atcccatttg gctgctcatg gccaatgctg accagcgcgt   3660

catgatgacc taccaggtgc cctccaggga catgacctct gtgctgaagc aggatcggga   3720

gcggctccga gccatgcaga agcagcagcc tcggttttct gaggaccagc ggcgggaact   3780

gggtgctgtg cactcctggg tccggaaggg ccaactgcct cgggctcttg atgtgatggc   3840

ctgtgtggac tgtgggagca gcacccaaga tcctggtcac cctgatgacc cactcttctc   3900

agagctggat ggactggggc tggagcccat ggaagagggt ggaggcgagc agggcagcag   3960

cggtggcggc agtggtgagg gagagggctg cgaggaggcc caaggcgggg ccaaggcttc   4020

aagctctcag gacttggcta tggaggagga ggaagaaggc aggagctcat ccagtccagc   4080

cttacctaca gcaggaaact gcaccagcta gactccattc tgggaccatc tccaggagtc   4140

catgagaggc tttcttctcc tatgtcccaa ttctcagaac tcagatgtgg ctagaccaac   4200

cagtgggaaa ctgccccagc ttctcccacc atagggggcc ggacccccat caccagccta   4260

ggatccaggg gctgcctctg gcctcttagg gagcagagag cagaactccg cagcccagcc   4320

cagaggagtg tcacctccca cctttggaga ggaatccttc cctcccctgg acaaagttgc   4380

tgacaagctg ctgaagtggc ctctccatat tccagctgag cctgaatctg actcttgagg   4440

gttggggctg cacttattta ttgcggggag acagctctct ctcccacctc ctccccagat   4500

gggaggagag cctgaggccc aagcaggacc cgggggttcc agcccctagc tgctctggag   4560

tgggggaggt tggtggacca tggagtccct ggtgctgccc ctcaggtggg acccaggcgt   4620

tctcagctgt accctctgcc gatggcattt gtgtttttga tatttgtgtc tgttactact   4680

tttttaatac aaaaagataa aaacgcccaa aaaaaaa                            4717


<210>  844
<211>  4475
<212>  DNA
<213>  Human

<400>  844
cgggtggctt tgcgggcgct cgcggtaagt ttgcgccaag tgcgcggcag ccgggacgca     60

gacggcggcg gcggcgagag gcggagcccg gggaccaccc cccatcaccc tccccccagt    120

cacctcacgt accacaacct cacgtaacct ctcacccccc ctccgatacc cccagccccg    180

ggatggcagc gcccgccagc cttcccggcc ggaccggctg tcgccagtgc cggctttagc    240

ctgtgggact aggccccgcc gaggcctgac ccccggagcc gggacccact gtgcagccag    300

cagccgggcc gggactgagg ggccgctccc ccctcgcggc ccgtcgggag gacgctgtcg    360

tcccggggac tgggggccgg ggggtggggg ggagccaggg cgaggaagtc gggacccgta    420

ttgggaaaaa agcggggccg gggtcaggag cgccccctcc cctcacctcc cccctccccc    480

cggggttggg ggggccggag cagagagcac ccagcccggg aggtggatga atgtgggaga    540

aaatggagac caagacgatc gtgtacgact tggacacatc aggggggctg atggagcaaa    600

tccaagctct gctggctccc cccaagacgg acgaggcaga aaagcgcagt cggaagcctg    660

agaaggagcc ccggagaagc ggcagggcca ccaaccacga cagctgcgat agctgcaagg    720

aaggtggaga tctcctgtgc tgcgaccact gcccggctgc cttccacctc cagtgctgta    780

accctccact gagtgaagaa atgttgcctc ctggagagtg gatgtgtcac cggtgcactg    840

ttcgccgaaa gaaacgagag cagaaaaagg agctgggtca tgtcaatgga ctggtggaca    900

aatctggcaa acggactaca tcccccagca gtgacactga cttgttggac agatcggcca    960

gcaaaactga actaaaggcc attgcccatg cccggatcct ggaaaggaga gccagcaggc   1020

ctggcacacc cacatccagc gccagcacag agactcccac ctctgagcag aatgatgtcg   1080

acgaagacat cattgacgtg gatgaggaac cagtagcagc ggagccagac tatgtgcagc   1140

cccagctgag gcggcccttt gagctgctga ttgctgccgc catggagcgg aaccccaccc   1200

aatttcagtt gcccaatgaa ctgacttgta ccactgcact accaggttct agcaagagga   1260

gaagaaagga ggaaaccaca gggaaaaatg ttaagaagac acagcatgaa ttagatcaca   1320

atggtctcgt tcccttaccc gtcaaagtct gcttcacgtg taacaggagt tgccgtgtgg   1380

ctcctctcat ccagtgtgac tattgccctc tcctgtttca catggattgc ctcgagccgc   1440

cgctcactgc catgcccctg ggcagatgga tgtgtccgaa tcacatcgaa catgtggtgc   1500

tgaaccagaa gaatatgaca ctgagcaatc ggtgccaggt gtttgatcgt ttccaggaca   1560

ccgtttcgca gcatgtcgtc aaagtggact tcctgaaccg aatccacaag aagcaccccc   1620

ctaaccggcg tgtgctccag tcggtcaaaa gaagaagctt gaaggttcct gatgctataa   1680

aatctcagta ccagtttcca ccccctctca ttgcacccgc ggccattcgg gacggggagc   1740

tgatctgcaa tgggatccct gaggaatcac agatgcacct tttgaactct gagcacttag   1800

ccacccaagc agagcagcaa gagtggctct gtagtgttgt tgcgctccag tgcagcatat   1860

tgaaacattt atctgctaag cagatgcctt cgcattggga ctctgaacag acagagaagg   1920

ctgatattaa gcctgttatt gtgactgaca gctcagtcac cacctccctg caaacagctg   1980

acaagacacc tacaccttcc cactacccct tgtcctgccc ctcagggatt agcacccaga   2040

attccctgag ctgctctcca ccccaccagt ccccagccct agaggacatc ggctgcagtt   2100

cttgtgcgga aaaatccaag aaaacccctt gtgggactgc caatgggcca gtgaacacag   2160

aggtgaaagc taatggccca cacctctaca gcagccctac tgattccacg gacccccggc   2220

gacttccagg cgctaacacc ccactaccag gcctctcaca ccggcaaggc tggccccggc   2280

ccctcacgcc accagcggct gggggccttc agaaccacac cgtcggcatc attgtgaaga   2340

cagagaatgc cactggcccc agctcttgcc cccagaggag tttggttcct gtcccaagcc   2400

tgcccccttc cattcccagc tcttgtgcca gcatcgagaa caccagcact ttgcaaagaa   2460

agactgtcca atcacagata ggacctccgt tgacagattc aaggccactg ggctcacccc   2520

caaacgccac ccgggtgctc actcccccgc aagcagcagg agatggtatc ttggccacaa   2580

cagccaacca acgattcagc tcaccagcgc catcgtcaga tggcaaggtc agccccggca   2640

cgttatccat aggaagcgct ttaaccgtac cctctttccc agccaactct actgccatgg   2700

tggacctcac caactcactt cgagcattta tggatgtcaa tggagaaatc gagataaata   2760

tgctggacga gaagctgatc aagtttctgg ccttgcagag aatacatcag cttttcccct   2820

cccgggtcca accttcaccg ggcagtgtcg ggacacatca gctggcttct ggagggcacc   2880

acatagaagt gcaaagaaag gaggtacagg cccgagctgt gttctacccc ctcttagggt   2940

tgggaggagc tgtgaacatg tgctatcgaa ccctctacat cgggacagga gctgacatgg   3000

atgtgtgcct tacaaactat ggtcactgta actacgtgtc cgggaaacat gcctgcatat   3060

tctacgatga gaataccaaa cattatgagc tgttaaacta cagtgagcat gggacaacgg   3120

tggacaatgt gctgtattca tgtgacttct cggagaagac cccgccaacc cccccaagca   3180

gtattgttgc caaagtgcag agtgtcatca ggcgccgccg gcaccagaaa caggacgaag   3240

agccaagtga ggaggcagcc atgatgagtt cccaggccca ggggccgcag cggagaccct   3300

gcaattgcaa agccagcagc tcgagcttga ttgggggcag tggggccggc tgggagggca   3360

cagccttact gcaccatggc agctacatca agctgggctg cctgcagttt gtcttcagca   3420

tcactgagtt tgcgaccaaa cagcccaaag gcgatgccag cctgctgcag gatggggtct   3480

tggccgagaa gctctctctc aagccccacc agggccctgt gctgcgctcc aactctgttc   3540

cttaggactg gcggctaccc cgccactggc ctgtacaccc acccaagact cctgcaatgc   3600

aaaaatgtac acaaaccaag cccgggtgtt ttctatactc taccagaaac ccttcaacta   3660

caatctttgc atgaaatgaa gaaaaccttt tgactgtttt ttaaaaatcc tttttctttt   3720

ctcaagttct agggggcatt tgcacatata tttgtactca acatttcatg ggaaagcggc   3780

agacctgagc tgaggaacag cgtgggcagg gagggaaaga cccagggtct ggacacttcc   3840

tccaacacaa aacccttccc cacccacctc ctgctccctc cccctcgccc accattgtaa   3900

aataatcaga aacttgttct attttgtggc agtgacaata gttttatatt aaaagaaaaa   3960

atacagtttt catacagcaa aatctataca atatcattgt tttatttaat ataaagatcg   4020

ctacccacct tccttccatg gttcccaccc tccacgttat tttccctttc tgcagcggtt   4080

gcactacagg tagctactgt gtattatgga caaatgagaa atgaattctt tttctggctg   4140

tccatctatt ttatttcaaa taaggaaaag tgtatttgga ttttgtgtaa atacatctag   4200

tgatgacatt ttttcaatgt ttttaaaaac cgtgtacagt actacatgtg gtagagcgtt   4260

ttctcaaatt gtctattgta gcaaaaatgt ttttgtcgta aacctgtttt gtctcctttt   4320

tttgttctct tgccacttct ctcctcttcc tcctgcccct ggttccctcc tctcctccca   4380

cccccacaac cagtaccaat gtacatagta attgtaatgt tttagacttt acagaaactt   4440

tcctgtattc tgtatataaa aaacaaaaat acttc                              4475


<210>  845
<211>  2021
<212>  DNA
<213>  Human

<400>  845
gcagggattt ggcaacctca gagccgcgag gaggaggcgg agtcgcggag agtttgagta     60

tttccgtcca atcaaaagga gactgtaaga ggaggaggag gaggagatga ctggggagcg    120

ggagctggag aatactgccc agttactcta gcgcgccagg ccgaaccgca gcttcttggc    180

ttaggtactt ctactcacag cggccgattc cgaggccaac tccagcaatg gcttttgcaa    240

atctgcggaa agtgctcatc agtgacagcc tggacccttg ctgccggaag atcttgcaag    300

atggagggct gcaggtggtg gaaaagcaga accttagcaa agaggagctg atagcggagc    360

tgcaggactg tgaaggcctt attgttcgct ctgccaccaa ggtgaccgct gatgtcatca    420

acgcagctga gaaactccag gtggtgggca gggctggcac aggtgtggac aatgtggatc    480

tggaggccgc aacaaggaag ggcatcttgg ttatgaacac ccccaatggg aacagcctca    540

gtgccgcaga actcacttgt ggaatgatca tgtgcctggc caggcagatt ccccaggcga    600

cggcttcgat gaaggacggc aaatgggagc ggaagaagtt catgggaaca gagctgaatg    660

gaaagaccct gggaattctt ggcctgggca ggattgggag agaggtagct acccggatgc    720

agtcctttgg gatgaagact atagggtatg accccatcat ttccccagag gtctcggcct    780

cctttggtgt tcagcagctg cccctggagg agatctggcc tctctgtgat ttcatcactg    840

tgcacactcc tctcctgccc tccacgacag gcttgctgaa tgacaacacc tttgcccagt    900

gcaagaaggg ggtgcgtgtg gtgaactgtg cccgtggagg gatcgtggac gaaggcgccc    960

tgctccgggc cctgcagtct ggccagtgtg ccggggctgc actggacgtg tttacggaag   1020

agccgccacg ggaccgggcc ttggtggacc atgagaatgt catcagctgt ccccacctgg   1080

gtgccagcac caaggaggct cagagccgct gtggggagga aattgctgtt cagttcgtgg   1140

acatggtgaa ggggaaatct ctcacggggg ttgtgaatgc ccaggccctt accagtgcct   1200

tctctccaca caccaagcct tggattggtc tggcagaagc tctggggaca ctgatgcgag   1260

cctgggctgg gtcccccaaa gggaccatcc aggtgataac acagggaaca tccctgaaga   1320

atgctgggaa ctgcctaagc cccgcagtca ttgtcggcct cctgaaagag gcttccaagc   1380

aggcggatgt gaacttggtg aacgctaagc tgctggtgaa agaggctggc ctcaatgtca   1440

ccacctccca cagccctgct gcaccagggg agcaaggctt cggggaatgc ctcctggccg   1500

tggccctggc aggcgcccct taccaggctg tgggcttggt ccaaggcact acgcctgtac   1560

tgcaggggct caatggagct gtcttcaggc cagaagtgcc tctccgcagg gacctgcccc   1620

tgctcctatt ccggactcag acctctgacc ctgcaatgct gcctaccatg attggcctcc   1680

tggcagaggc aggcgtgcgg ctgctgtcct accagacttc actggtgtca gatggggaga   1740

cctggcacgt catgggcatc tcctccttgc tgcccagcct ggaagcgtgg aagcagcatg   1800

tgactgaagc cttccagttc cacttctaac cttggagctc actggtccct gcctctgggg   1860

cttttctgaa gaaacccacc cactgtgatc aatagggaga gaaaatccac attcttgggc   1920

tgaacgcggg cctctgacac tgcttacact gcactctgac cctgtagtac agcaataacc   1980

gtctaataaa gagcctaccc ccaactcctt ctgcaaaaaa a                       2021


<210>  846
<211>  2369
<212>  DNA
<213>  Human

<400>  846
cctgggcgcc agcgcagcgt agcaaatcca ggcagcgcca cgcgcggccg gggccgggcg     60

gaaccgagaa gccgggaccg cgctgcgacg cgccggccgc atggagcctg ccgccggttt    120

cctgtctccg cgccccttcc agcgtgcggc cgccgcgccc gctcccccgg ccgggcccgg    180

gccgcctccg agtgccttgc gcggacctga gctggagatg ctggccgggc taccgacgtc    240

agaccccggg cgcctcatca cggacccgcg cagcggccgc acctacctca aaggccgctt    300

gttgggcaag gggggcttcg cccgctgcta cgaggccact gacacagaga ctggcagcgc    360

ctacgctgtc aaagtcatcc cgcagagccg cgtcgccaag ccgcatcagc gcgagaagat    420

cctaaatgag attgagctgc accgagacct gcagcaccgc cacatcgtgc gtttttcgca    480

ccactttgag gacgctgaca acatctacat tttcttggag ctctgcagcc gaaagtccct    540

ggcccacatc tggaaggccc ggcacaccct gttggagcca gaagtgcgct actacctgcg    600

gcagatcctt tctggcctca agtacttgca ccagcgcggc atcttgcacc gggacctcaa    660

gttgggaaat tttttcatca ctgagaacat ggaactgaag gtgggggatt ttgggctggc    720

agcccggttg gagcctccgg agcagaggaa gaagaccatc tgtggcaccc ccaactatgt    780

ggctccagaa gtgctgctga gacagggcca cggccctgag gcggatgtat ggtcactggg    840

ctgtgtcatg tacacgctgc tctgcgggag ccctcccttt gagacggctg acctgaagga    900

gacgtaccgc tgcatcaagc aggttcacta cacgctgcct gccagcctct cactgcctgc    960

ccggcagctc ctggccgcca tccttcgggc ctcaccccga gaccgcccct ctattgacca   1020

gatcctgcgc catgacttct ttaccaaggg ctacaccccc gatcgactcc ctatcagcag   1080

ctgcgtgaca gtcccagacc tgacaccccc caacccagct aggagtctgt ttgccaaagt   1140

taccaagagc ctctttggca gaaagaagaa gagtaagaat catgcccagg agagggatga   1200

ggtctccggt ttggtgagcg gcctcatgcg cacatccgtt ggccatcagg atgccaggcc   1260

agaggctcca gcagcttctg gcccagcccc tgtcagcctg gtagagacag cacctgaaga   1320

cagctcaccc cgtgggacac tggcaagcag tggagatgga tttgaagaag gtctgactgt   1380

ggccacagta gtggagtcag ccctttgtgc tctgagaaat tgtatagcct tcatgccccc   1440

agcggaacag aacccggccc ccctggccca gccagagcct ctggtgtggg tcagcaagtg   1500

ggttgactac tccaataagt tcggctttgg gtatcaactg tccagccgcc gtgtggctgt   1560

gctcttcaac gatggcacac atatggccct gtcggccaac agaaagactg tgcactacaa   1620

tcccaccagc acaaagcact tctccttctc cgtgggtgct gtgccccggg ccctgcagcc   1680

tcagctgggt atcctgcggt acttcgcctc ctacatggag cagcacctca tgaagggtgg   1740

agatctgccc agtgtggaag aggtagaggt acctgctccg cccttgctgc tgcagtgggt   1800

caagacggat caggctctcc tcatgctgtt tagtgatggc actgtccagg tgaacttcta   1860

cggggaccac accaagctga ttctcagtgg ctgggagccc ctccttgtga cttttgtggc   1920

ccgaaatcgt agtgcttgta cttacctcgc ttcccacctt cggcagctgg gctgctctcc   1980

agacctgcgg cagcgactcc gctatgctct gcgcctgctc cgggaccgca gcccagccta   2040

ggacccaagc cctgaggcct gaggcctgtg cctgtcaggc tctggccctt gcctttgtgg   2100

ccttccccct tcctttggtg cctcactggg ggctttgggc cgaatccccc agggaatcag   2160

ggaccagctt tactggagtt gggggcggct tgtcttcgct ggctcctacc ccatctccaa   2220

gataagcctg agccttagct cccagctagg gggcgttatt tatggaccac ttttatttat   2280

tgtcagacac ttatttattg ggatgtgagc cccagggggg cctcctccta ggataataaa   2340

caattttgca gaattggaaa aaaaaaaaa                                     2369


<210>  847
<211>  6356
<212>  DNA
<213>  Human

<400>  847
ccttggcggc ggacgtgcag agaatctcga tgctggcctg gagcagaaac tgagctggac     60

cactggagcc tcggtgaggg ggtgcggggg gcaatggcac tgcagctctg ggccctgacc    120

ctgctgggcc tgctgggcgc aggtgccagc ctgaggcccc gcaagctgga cttcttccgc    180

agcgagaaag agctgaacca cctggctgtg gatgaggcct caggcgtggt gtacctgggg    240

gcggtgaatg ccctctacca gctggatgcg aagctgcagc tggagcagca ggtggccacg    300

ggcccggccc tggacaacaa gaagtgcacg ccgcccatcg aggccagcca gtgccatgag    360

gctgagatga ctgacaatgt caaccagctg ctgctgctcg accctcccag gaagcgcctg    420

gtggagtgcg gcagcctctt caagggcatc tgcgctctgc gcgccctgag caacatctcc    480

ctccgcctgt tctacgagga cggcagcggg gagaagtctt tcgtggccag caatgatgag    540

ggcgtggcca cagtggggct ggtgagctcc acgggtcctg gtggtgaccg cgtgctgttt    600

gtgggcaaag gcaatgggcc acacgacaac ggcatcatcg tgagcactcg gctgttggac    660

cggactgaca gcagggaggc ctttgaagcc tacacggacc acgccaccta caaggccggc    720

tacctgtcca ccaacacaca gcagttcgtg gcggccttcg aggacggccc ctacgtcttc    780

tttgtcttca accagcagga caagcacccg gcccggaacc gcacgctgct ggcacgcatg    840

tgcagagaag accccaacta ctactcctac ctggagatgg acctgcagtg ccgggacccc    900

gacatccacg ccgctgcctt tggcacctgc ctggccgcct ccgtggctgc gcctggctct    960

ggcagggtgc tatatgctgt cttcagcaga gacagccgga gcagtggggg gcccggtgcg   1020

ggcctctgcc tgttcccgct ggacaaggtg cacgccaaga tggaggccaa ccgcaacgcc   1080

tgttacacag gcacccggga ggcccgtgac atcttctaca agcccttcca cggcgatatc   1140

cagtgcggcg gccacgcgcc gggctccagc aagagcttcc catgtggctc ggagcacctg   1200

ccctacccgc tgggcagccg cgacgggctc agaggcacag ccgtgctgca gcgtggaggc   1260

ctgaacctca cggccgtgac ggtcgccgcc gagaacaacc acactgttgc ttttctgggc   1320

acctctgatg gccggatcct caaggtgtac ctcaccccag atggcacctc ctcagagtac   1380

gactctatcc ttgtggagat aaacaagaga gtcaagcgcg acctggtact gtctggagac   1440

ctgggcagcc tgtacgccat gacccaggac aaggtgttcc ggctgccggt gcaggagtgc   1500

ctgagctacc cgacctgcac ccagtgccgc gactcccagg acccctactg cggctggtgc   1560

gtcgtcgagg gacgatgcac ccggaaggcc gagtgtccgc gggccgagga ggccagccac   1620

tggctgtgga gccgaagcaa gtcctgcgtg gccgtcacca gcgcccagcc acagaacatg   1680

agccggcggg cccaggggga ggtgcagctg accgtcagcc ccctccctgc cctgagcgag   1740

gaggacgagt tgctgtgcct ttttggggag tcgccgccac accccgcccg cgtggagggc   1800

gaggccgtca tctgcaactc cccaagcagc atccccgtca caccgccagg ccaggaccac   1860

gtggccgtga ccatccagct cctccttaga cgaggcaaca tcttcctcac gtcctaccag   1920

taccccttct acgactgccg ccaggccatg agcctggagg agaacctgcc gtgcatctcc   1980

tgcgtgagca accgctggac ctgccagtgg gacctgcgct accacgagtg ccgggaggct   2040

tcgcccaacc ctgaggacgg catcgtccgt gcccacatgg aggacagctg tccccagttc   2100

ctgggaccca gccccctggt gatccccatg aaccacgaga cagatgtgaa cttccagggc   2160

aagaacctgg acaccgtgaa gggttcctcc ctgcacgtgg gcagtgactt gctcaagttc   2220

atggagccgg tgaccatgca ggaatctggg accttcgcct ttcggacccc aaagctgtcc   2280

cacgatgcca acgagacgct gcccctgcac ctctacgtca agtcttacgg caagaatatc   2340

gacagcaagc tccatgtgac cctctacaac tgctcctttg gccgcagcga ctgcagcctg   2400

tgccgggccg ctaaccccga ctacaggtgt gcgtggtgcg ggggccagag caggtgcgtg   2460

tatgaggccc tgtgcaacac cacctccgag tgcccgccgc ccgtcatcac caggatccag   2520

cctgagacgg gccccctggg tgggggcatc cgcatcacca tcctggggtc caatttgggc   2580

gtccaagcag gggacatcca gaggatctct gtggccggcc ggaactgctc ctttcagccg   2640

gaacgttact ccgtgtccac ccggatcgtg tgtgtgatcg aggctgcgga gacgcctttc   2700

acggggggtg tcgaggtgga cgtcttcggg aaactgggcc gttcgcctcc caatgtccag   2760

ttcaccttcc aacagcccaa gcctctcagt gtggagccgc agcagggacc gcaggcgggc   2820

ggcaccacac tgaccatcca cggcacccac ctggacacgg gctcccagga ggacgtgcgg   2880

gtgaccctca acggcgtccc gtgtaaagtg acgaagtttg gggcgcagct ccagtgtgtc   2940

actggccccc aggcgacacg gggccagatg cttctggagg tctcctacgg ggggtccccc   3000

gtgcccaacc ccggcatctt cttcacctac cgcgaaaacc ccgtactgcg agccttcgag   3060

ccgctacgaa gctttgccag tggtggccgc agcatcaacg tcacgggtca gggcttcagc   3120

ctgatccaga ggtttgccat ggtggtcatc gcggagcccc tgcagtcctg gcagccgccg   3180

cgggaggctg aatccctgca gcccatgacg gtggtgggta cagactacgt gttccacaat   3240

gacaccaagg tcgtcttcct gtccccggct gtgcctgagg agccagaggc ctacaacctc   3300

acggtgctga tcgagatgga cgggcaccgt gccctgctca gaacagaggc cggggccttc   3360

gagtacgtgc ctgaccccac ctttgagaac ttcacaggtg gcgtcaagaa gcaggtcaac   3420

aagctcatcc acgcccgggg caccaatctg aacaaggcga tgacgctgca ggaggccgag   3480

gccttcgtgg gtgccgagcg ctgcaccatg aagacgctga cggagaccga cctgtactgt   3540

gagcccccgg aggtgcagcc cccgcccaag cggcggcaga aacgagacac cacacacaac   3600

ctgcccgagt tcattgtgaa gttcggctct cgcgagtggg tgctgggccg cgtggagtac   3660

gacacacggg tgagcgacgt gccgctcagc ctcatcttgc cgctggtcat cgtgcccatg   3720

gtggtcgtca tcgcggtgtc tgtctactgc tactggagga agagccagca ggccgaacga   3780

gagtatgaga agatcaagtc ccagctggag ggcctggagg agagcgtgcg ggaccgctgc   3840

aagaaggaat tcacagacct gatgatcgag atggaggacc agaccaacga cgtgcacgag   3900

gccggcatcc ccgtgctgga ctacaagacc tacaccgacc gcgtcttctt cctgccctcc   3960

aaggacggcg acaaggacgt gatgatcacc ggcaagctgg acatccctga gccgcggcgg   4020

ccggtggtgg agcaggccct ctaccagttc tccaacctgc tgaacagcaa gtctttcctc   4080

atcaatttca tccacaccct ggagaaccag cgggagttct cggcccgcgc caaggtctac   4140

ttcgcgtccc tgctgacggt ggcgctgcac gggaaactgg agtactacac ggacatcatg   4200

cacacgctct tcctggagct cctggagcag tacgtggtgg ccaagaaccc caagctgatg   4260

ctgcgcaggt ctgagactgt ggtggagagg atgctgtcca actggatgtc catctgcctg   4320

taccagtacc tcaaggacag tgccggggag cccctgtaca agctcttcaa ggccatcaaa   4380

catcaggtgg aaaagggccc ggtggatgcg gtacagaaga aggccaagta cactctcaac   4440

gacacggggc tgctggggga tgatgtggag tacgcacccc tgacggtgag cgtgatcgtg   4500

caggacgagg gagtggacgc catcccggtg aaggtcctca actgtgacac catctcccag   4560

gtcaaggaga agatcattga ccaggtgtac cgtgggcagc cctgctcctg ctggcccagg   4620

ccagacagcg tggtcctgga gtggcgtccg ggctccacag cgcagatcct gtcggacctg   4680

gacctgacgt cacagcggga gggccggtgg aagcgcgtca acacccttat gcactacaat   4740

gtccgggatg gagccaccct catcctgtcc aaggtggggg tctcccagca gccggaggac   4800

agccagcagg acctgcctgg ggagcgccat gccctcctgg aggaggagaa ccgggtgtgg   4860

cacctggtgc ggccgaccga cgaggtggac gagggcaagt ccaagagagg cagcgtgaaa   4920

gagaaggagc ggacgaaggc catcaccgag atctacctga cgcggctgct ctcagtcaag   4980

ggcacactgc agcagtttgt ggacaacttc ttccagagcg tgctggcgcc tgggcacgcg   5040

gtgccacctg cagtcaagta cttcttcgac ttcctggacg agcaggcaga gaagcacaac   5100

atccaggatg aagacaccat ccacatctgg aagacgaaca gcttaccgct ccggttctgg   5160

gtgaacatcc tcaagaaccc ccacttcatc tttgacgtgc atgtccacga ggtggtggac   5220

gcctcgctgt cagtcatcgc gcagaccttc atggatgcct gcacgcgcac ggagcataag   5280

ctgagccgcg attctcccag caacaagctg ctgtacgcca aggagatctc cacctacaag   5340

aagatggtgg aggattacta caaggggatc cggcagatgg tgcaggtcag cgaccaggac   5400

atgaacacac acctggcaga gatttcccgg gcgcacacgg actccttgaa caccctcgtg   5460

gcactccacc agctctacca atacacgcag aagtactatg acgagatcat caatgccttg   5520

gaggaggatc ctgccgccca gaagatgcag ctggccttcc gcctgcagca gattgccgct   5580

gcactggaga acaaggtcac tgacctctga cctacaatct ccagtgctgc cttgggacat   5640

aggtacctga ggtacctgag agcccctcag gggaggaggc cgagtggctg tggctgaggc   5700

ccccaccctc ccctggaacg cgccccaagc cggagtgggt gcagccggaa cccgcccagc   5760

gtctagactg tagcatcttc ctctgagcaa taccgccggg caccgcacca gcaccagccc   5820

cagccccagc tccctccggc cgcagaacca gcatcgggtg ttcactgtcg agtctccagt   5880

gatttgaaaa tgtgccttac gctgccacgc tgggggcagc tggcctccgc ctccgcccac   5940

gcaccagcag ccgcctccat gccctaggtt gggcccctgg gggatctgag ggcctgtggc   6000

ccccagggca agttcccaga tcctatgtct gtctgtccac cacgagatgg gaggaggaga   6060

aaaagcggta cgatgccttc ctgacctcac cggcctcccc aagggtgccg gcactctggg   6120

tggactcacg gctgctgggc cccacgtcaa aggtcaagtg agacgtaggt caagtcctac   6180

gtcggggccc agacatcctg gggtcctggt ctgtcagaca ggctgcccta gagccccacc   6240

cagtccgggg ggactgggag cagttccaag accaccccac ccctttttgt aaatcttgtt   6300

cattgtaaat caaatacagc gtctttttca ctctgaaaaa aaaaaaaaaa aaaaaa       6356


<210>  848
<211>  1994
<212>  DNA
<213>  Human

<400>  848
tggcttctgc gtggtgcagc tgcgcacgtg tttcagccgg cagcgcttta agatttccgg     60

ggatggaatc cgaaatggaa acgcagagcg ccagggcaga ggagggcttt acccaggtca    120

cccgcaaggg tggccgacgg gcgaagaaac gacaggctga acagctgtcc gcagcaggag    180

agggcgggga tgcgggccgc atggacacag aggaggccag gccggcgaag aggcccgtct    240

tcccacccct ctgtggggac gggctcctga gtgggaaaga agaaacaagg aaaattccag    300

tcccagctaa cagatacaca ccattgaaag aaaactggat gaagatattt actcctattg    360

tggaacattt gggacttcag atacgcttta acttgaaatc aaggaatgta gaaatcagga    420

cttgtaaaga aaccaaggat gttagtgctc tgacaaaagc agctgatttt gtgaaagctt    480

ttattctcgg ctttcaggtg gaggatgcac ttgccctcat caggttggat gacctcttcc    540

tagagtcttt tgaaattaca gatgttaaac ccctaaaggg agaccatcta tccagggcaa    600

taggaagaat cgctggcaaa ggaggaaaaa ccaaattcac catagagaat gtgacacgga    660

caaggatagt tttggctgat gtgaaagttc acatccttgg ctccttccaa aatatcaaga    720

tggcaagaac tgccatttgc aacctaatct tgggaaatcc tccttccaag gtttatggca    780

atattcgagc tgtggctagc agatcagcag atcgattctg atttcaagtc agagactttt    840

tatcttgcct ttggactctg gtgaaaaata ctttacagtg gtcggtcaca agaaaccagc    900

tgaacaattt cagtcatttg aagcctccgt cccttcttcc attctcagcc agaagcataa    960

acagaaaaga aagatttaag aggattcaca ctcaacaggt tttaggataa tttaaatatc   1020

aaaaattgat tgttatactt aacacattag gtataattta tcatttatct gaaatcacat   1080

gtagcagatt gcatagtctg taatcctctc agagggaaac ttcttgttta aacagctcta   1140

tatggattta tacttttata tttataaatt tataacttca tacaaattta taaacatttc   1200

tttataaatt gtaatttaat agattatctc agaaaaacct ctctgaatga tgacccttcc   1260

ttaatactgg gtgatgtgtg aatatttgtt tgttggcaga cagggtctca ctttgtcacc   1320

caggctagag tgcagtggtg caatctcagc tcactgcagc ctctgcctcc tgagttcaag   1380

tgatcctcct gcttcagcct ccctagtagc tgggactaca ggtatgcacc accatgcctg   1440

gctaattttt tgtatttttt gtagagatgg ggtttcgcca tgttgaccag gctggtcttg   1500

aactcctggc ctcaagggat ccgtccgcct cagcctccca aagtgctggg attacaggca   1560

taagccactg cgcctggcct tgatgtgtga atatttgaga ggtcataagc agtggttttg   1620

gccataccgt attataccat atacatcagt aagagctcat cttggaacct gttttgcagt   1680

ttcttgcagt ttcaaaaatt aaagacctac atcacagggt taatgtgaag aaagctttat   1740

ttttcaaatg agtatttaat gaaagtatac ataaccaatg ttgggtatac agatgcttct   1800

caacttatga tgggtttagg tccagataag cccactgtga gttgaaaata ccaaaagtca   1860

aacatcatag cttagcctac cttaaaaggg ctccgaacac tacattagcc tacagttggg   1920

caaaatcgtc taatacaaag cctattttat aataaagtat gttgaatatc tcatgtaaaa   1980

aaaaaaaaaa aaaa                                                     1994


<210>  849
<211>  1045
<212>  DNA
<213>  Human

<400>  849
actatccggc gccgagccgg aggggggaaa cggcgcccgc cgcccgcccg gagcccgcga     60

gcaaccccag tcccccccac ccgcgcgtgg cggcgccggc tccctagcca ccgcggcccc    120

accctcttcc ggcctcagct gtccgggctg ctttcgcctc cgcctgtgga tgctgcgcct    180

ctccgaacgc aacatgaagg tgctccttgc cgccgccctc atcgcggggt ccgtcttctt    240

cctgctgctg ccgggacctt ctgcggccga tgagaagaag aaggggccca aagtcaccgt    300

caaggtgtat tttgacctac gaattggaga tgaagatgta ggccgggtga tctttggtct    360

cttcggaaag actgttccaa aaacagtgga taattttgtg gccttagcta caggagagaa    420

aggatttggc tacaaaaaca gcaaattcca tcgtgtaatc aaggacttca tgatccaggg    480

cggagacttc accaggggag atggcacagg aggaaagagc atctacggtg agcgcttccc    540

cgatgagaac ttcaaactga agcactacgg gcctggctgg gtgagcatgg ccaacgcagg    600

caaagacacc aacggctccc agttcttcat cacgacagtc aagacagcct ggctagatgg    660

caagcatgtg gtgtttggca aagttctaga gggcatggag gtggtgcgga aggtggagag    720

caccaagaca gacagccggg ataaacccct gaaggatgtg atcatcgcag actgcggcaa    780

gatcgaggtg gagaagccct ttgccatcgc caaggagtag ggcacaggga catctttctt    840

tgagtgaccg tctgtgcagg ccctgtagtc cgccacaggg ctctgagctg cactggcccc    900

ggtgctggca tctggtggag cggacccact cccctcacat tccacaggcc catggactca    960

cttttgtaac aaactcctac caacactgac caataaaaaa aaatgtgggt tttttttttt   1020

ttaatataaa aaaaaaaaaa aaaaa                                         1045


<210>  850
<211>  4118
<212>  DNA
<213>  Human

<400>  850
aaaagcagca tcagacaaga gctttattaa tcccttacac gagcaaatgc gatctctgac     60

ctactagact tgttttccta caatttcaca aaaagcctcg ctagaggaat gtgcaaggac    120

agaagggaaa ctgaggagac ccgcaactca ttagcgaaat aatagggtgc acttcaataa    180

aaatgcggtc ctgaagtgga gcagactcac cggcaaggag cccggaaaat cgtcaggggc    240

ggcggcaaaa tactatcaaa tcagcctggg aagcatcttt tcgctcagca agttcaagag    300

aacaaatatg ttacaatcct tgcctattct tgcctccact tcataatgtc ataaaagcca    360

cctggggtgt catttatcaa cctctctcca gcccactctt ccaaaataac actacagttt    420

cctacatgtg tatttttgcc aggactccaa agagccttgc taaagtggaa caagcaaaat    480

cctcccctgg cctcctggga ctgcagtcac caggctgtca aagcctcaat accccactga    540

gttccagaga agggtctcaa agctgggaga ggatcaaact aacatggagt agagaattga    600

actgtgaaaa agaagcccga gattccccag cgacgtggtg ttgcagcccc gttgaaggag    660

tcaacttgca ggctgttaaa gacctcaagt cattagcatc agctgctgca ctaaaggggc    720

aagtcagcgc ctctaagtgg cttagcgcac aaacgaggct cccgagacgg cctcggcaac    780

tccatcccct cctccaccac ccgctggatg tgaaaagctt tccggagccc atcttggggg    840

aagcttggta gtgttggcgc tcctgaagag agacgacgcc cgtttatcac ccccaggcaa    900

ctagctgcgc aaatcagcgg tggctccagg gctagagaat ccctggagct aaccgcaccc    960

ctctcccttt cacggaacgc ggactccggg gaaatacgca cggggtccgc acgcgctggg   1020

tgtccagctc tctgtcacag cttctccaag tgcctagtga aacggggaaa ggccctctcc   1080

aatcattttg gaagagccta aaaggcggca acaccaacac ctcttgacat ggaaatacac   1140

tgatacaata ggcaaaagga aacactcgat tgcatcttcc cggttccagg tggccttatt   1200

tgggagattc tatactgacc ttattcctgt gatggaggat actggcatcc agcgaggcat   1260

ctgggatgga gatgccaagg ctgtccaaca atgtctgaca gatattttta ccagcgttta   1320

caccacctgc gacatccctg agaatgctat atttggtccc tgtgtcctga gccatacttc   1380

cctatatgac agcatagctt tcatagctct caagtctact gacaagagaa cagtaccgta   1440

tatctttcgg gtagacacct cagcagcaaa tggttcctca gaaggtctca tgtggctgcg   1500

gttggtccaa tcggccagag ataaggaaga gcagaacctt gaagcctaca taaaaaacgg   1560

acagctgttc taccgctctc tccgcaggat tgccaaagac gaggagttac tagtttggta   1620

cgggaaagaa ctgactgagt tactcttgct ctgcccctct agatcccaca acaaaatgaa   1680

tgggtcgtcc ccttacacat gcctggaatg cagccaacgt ttccagtttg agttccccta   1740

tgtggcgcat ctgcgtttcc gctgccccaa gagacttcac agcgctgata taagtcccca   1800

agacgaacaa ggcggcggcg tgggcaccaa ggaccacggg ggcggcggcg gcggtggcaa   1860

agaccagcag cagcagcagc aggaggcacc tttaggcccg ggtcccaagt tttgcaaagc   1920

cggccccctc caccactacc catccccctc cccggaaagc agcaacccat ccgctgccgc   1980

cggcggcagc agcgcgaagc catccacaga cttccacaac ctggccaggg agctggaaaa   2040

ctcccgggga ggcagcagct gctccccagc ccagagcctc agcagcggta gcggcagcgg   2100

cggcggcggc ggccaccagg aggcggagct gagtcccgac ggcatcgcca cgggcggcgg   2160

caaaggaaag aggaaattcc cggaggaggc ggcggagggc ggcggtggcg ctggtctggt   2220

agggggccgg ggccgcttcg tagagcggcc cctcccggcc tccaaggagg atctggtgtg   2280

cacaccgcag cagtaccgag cctcgggcag ctacttcggc ctggaagaga acggccgcct   2340

cttcgcgccg ccaagtcccg agacgggcga ggcgaagcgc agcgccttcg tggaggtgaa   2400

gaaggctgcc cgcgcggcca gcctgcagga ggaggggaca gccgacggcg cgggagtcgc   2460

ctccgaggac caggacgctg gcggcggcgg cggctcctcc acgcccgcgg ccgcgtcacc   2520

ggtgggcgcc gagaagctgc tggccccgcg gcctgggggc ccgctgccca gccggctcga   2580

gggcggcagt cctgcgaggg gcagcgcctt cacttcggtg ccgcagctgg gcagcgcggg   2640

cagcaccagc ggtgggggcg gaacgggcgc cggggccgca ggcggcgcgg gcgggggcca   2700

gggcgccgcg tcggacgagc gcaaaagcgc cttctcgcag ccagcacgct ctttctcgca   2760

gctgtccccg ctggtgctgg gccagaagct gggcgcgctc gagccatgcc accccgccga   2820

cggcgtgggc cccaccagac tctatcccgc cgccgcggac cctctagcgg tgaagctcca   2880

gggggccgcg gacctgaacg gaggttgcgg gtccctgccg agcggcggcg gcggcctgcc   2940

taagcagagc cccttcctgt acgccaccgc cttctggccc aagagctccg ctgccgctgc   3000

agccgcggct gcggcggcgg ccgcggggcc cttgcagctg cagctgccct cggcgctcac   3060

gctgctgccg ccctccttca cctcgctgtg tctgcccgcg cagaactggt gcgccaagtg   3120

caatgcctcc ttccgcatga cctccgacct ggtgtaccat atgaggtcgc accacaaaaa   3180

ggagtatgcg atggagccct tggtgaagcg gcggcgagag gagaaactca agtgccccat   3240

ctgcaatgag tccttcaggg agcgccacca cctctccagg cacatgacct cgcataattg   3300

actcggaaag gaccccagct ttccacgcgc gcgcaagcac agttaagcca cctgcaggaa   3360

taaacacgcg agaacatcca ccgcttcctt gcaccccgaa accctgcaca aagacacata   3420

cattcaccgc ccccccgccc ccccaacgcg cacacacacg tcctctcctc ccaggaacct   3480

cattcaaata tttacccggg acacacaccc ccccccacac acacacacag acacactcac   3540

acacaagagc caggatggtg gagttttgat tgggtgggtt gtttgagggg gttttctttt   3600

gaatgcacgc attttcactt tccccaaaac aaaggtacat tttttaaaat gtcatatatt   3660

gcaacatatt gatgcatttg tcatacgttt ctacttaaat tattaagcac ttacgattta   3720

gatgtaataa ttatatgtaa gggcaaaatt tattttagat ataaagtaaa ggaggagggt   3780

gagatgcttt ctgcatttct tgatgacagt ttgtgttcct acaaaaataa acaaaatgaa   3840

taaaaaggga tcaccattca atttgagttt ccagggggaa gtgcatgtat aatgaaatga   3900

taatggactt caatgaagaa tgtcatcaat tatgtacata tgtattttct tttaatacaa   3960

agtgtaattt tgtgccagtg aaatggagtc tgaatagtta tgtgtttctt ttatccctgg   4020

aaatatttat taaactttat agtttatccg agtatgttgg atgctttgac aataaatgac   4080

tattttcttc aaagcaaaaa aaaaaaaaaa aaaaaaaa                           4118


<210>  851
<211>  3711
<212>  DNA
<213>  Human

<400>  851
atcttgttcc caggggcagt tggcggaaga gatcgagctc cctggctgcc ggctcgcctt     60

ctgcgtggag ttctcgcggt ctgggtttcg ctgtctgctc ttggcccggg gtcattttgt    120

cggcgtcggg tgccctctct tgcccagctg gggcacagcg aggcggcccc ttctcccgac    180

gacgttcgat ggagtagggt cccagaccgt tgtcccgaag agcgagatcg agcttggccc    240

cctccccccc ctccttccct ccctccttcc ttccgccgca acatggctaa caacagcccc    300

gcgctgacag gcaactcgca gccgcagcac caggcggctg cagctgcggc tcagcaacag    360

cagcagtgcg gcggcggcgg cgctaccaag ccggcggtct ccggcaagca gggcaatgtg    420

ctcccgctct ggggcaacga gaagaccatg aacctcaacc ccatgatcct gaccaacatc    480

ctgtcgtcgc cttacttcaa agtacagctc tacgagctca agacctacca cgaggtggtg    540

gacgagatct actttaaggt cacgcacgtt gaaccatggg agaaaggaag caggaaaaca    600

gcgggccaga cagggatgtg cggaggggtt cgaggtgttg gaacaggagg aattgtttct    660

acagcatttt gcctgttata caaattattt accctgaagt taactcgaaa gcaagtgatg    720

ggtcttataa cacacacaga ctctccatat attagagcgc ttggatttat gtatataaga    780

tatacacagc cccctacaga tctgtgggac tggtttgaat ccttccttga tgatgaagag    840

gacctagatg tgaaggctgg tggaggctgt gtaatgacca ttggagaaat gctacgatct    900

tttctcacaa aactggagtg gttttctacc ttgtttccaa gaattccagt tccagttcaa    960

aagaatattg atcaacagat taaaacccga cctagaaaaa tcaagaaaga tgggaaggaa   1020

ggtgctgagg aaatagacag acatgttgaa cgcagacgtt caaggtctcc aaggagatct   1080

ctgagtccac ggaggtcccc aagaaggtca agaagtagaa gtcatcatcg ggagggccat   1140

gggtcttcta gttttgacag agaattagaa agagagaaag aacgccagcg actagagcgt   1200

gaagccaaag aaagggagaa agaacggcga agatcccgaa gtattgaccg ggggttagaa   1260

cgcaggcgca gcagaagtag ggaaaggcat agaagtcgca gtcgaagtcg tgataggaaa   1320

ggggatagaa gggacaggga tcgagaaaga gagaaagaaa atgagagagg tagaagacga   1380

gatcgtgact atgataagga aagaggaaat gaacgagaaa aagagagaga gcgatcaaga   1440

gaaaggtcca aggaacagag aagtagggga gaggtagaag agaagaaaca taaagaagac   1500

aaagatgata ggcggcacag agatgacaaa agagattcca agaaagagaa aaaacacagt   1560

agaagcagaa gcagagaaag gaaacacaga agtaggagtc gaagtagaaa tgcagggaaa   1620

cgaagtagaa gtagaagcaa agagaaatca agtaaacata aaaatgaaag taaagaaaaa   1680

tcaaataaac gaagtcgaag tggcagtcaa ggaagaactg acagtgttga aaaatcaaaa   1740

aaacgggaac atagtcccag caaagaaaaa tctagaaagc gtagtagaag caaagaacgt   1800

tcccacaaac gagatcacag tgatagtaag gaccagtcag acaaacatga tcgtcgaagg   1860

agccaaagta tagaacaaga gagccaagaa aaacagcata aaaacaaaga tgagactgtg   1920

tgaaaatatt ttgtaaaagt ggatcacatt gaatcctata aatgattaaa tctgcttttt   1980

tcccccacgt tgagattgtg cagtagttcg cactcctcaa gctctccctg taggctgcat   2040

tttcatttcc tctttcgtgt agggaagtgc ctttgtaatt ccatttattg cattggtgtt   2100

ttcacccaat tgttaagttt gatacatgat gcacagattg ttcttgcatt tttattgttt   2160

gtttttgaaa tgtacagtct gtacatatgt cctgaaaatg ttttaattcc tttggcatgg   2220

ttgccatgtt ggttaaattt gtataaggca ataaactgcc actaatctat ttttgttttg   2280

taggtgtggg attatggttt gtgtactgaa gttagcatgg ctgtgctttt cgtaatagaa   2340

tgctaaagac tttgagaatg gatcttggat gtctattata ggagaagtat gtgctgccaa   2400

tgtacaagaa ggcagcattg taggattaac attcttgtct actgtatatt atcttggaag   2460

gctcttgtta atatgttaca cttaatattc tccacagtta cctttagaga gaatttatga   2520

gaagttagtt tctgatgcag aggtttttag gctgtgattt catcaaaagt ccttttagca   2580

ttctacctca aagggacact tagtatgcct aaaatttatt cacttagttt tcctttttta   2640

tttgaaaaaa tacatgacat gtaatctttt tttcttgaat tctttctcag attttaaagt   2700

actatattaa agaaaaaaat taatgtctaa agcctagcat tcttgcagaa ccctatacta   2760

acatgtaatg gggagagggt ggggcagatg agtagagaaa cagattcaag cctcaagctt   2820

ccaaagcatt tttataaatg gaaaatcctt aaattatgaa acagcttgat atagtgtcct   2880

ttttttaaaa ttcagaactt tttttattga taatggagat tgctgtttga gtttttaaac   2940

ttaatctaga acagaggagt attaaaagta atgctgtgct gcattattta agactatcag   3000

caaattattt gatagattgt tcttacaact tgtattctga ttacagaacc atcatgagtg   3060

tggaataaat actggattaa atcctttatc ctgggtcttg gcttttcccc catttgttaa   3120

atttttttag catatttata ttgtggaaat tgatgaaacg tcagtagagt cacactttgt   3180

gtacagggat gtcttagtgc ccagatgaca agtgaatttt ggagaaatgc atagactggg   3240

attgggcatg tggtaatcaa taatctttat tagaatactt gataatggca gttccctttg   3300

tcagtggttg ttacatgtgt catttgatta ctttgttcca tgtcaaagac gtttattggg   3360

atacctttta cttggacaat atgttagcat tttttaaaat ttggacttga aattctttaa   3420

gataattcac ccaattcttt ttagaaaaga aaatagaggc ccaaagtaat gatgtcagtg   3480

ctagggctaa aactcagtat tctgacagtg tagtgaacct ggcacgcaca ttgaggtttg   3540

ttttatctca ctggttatac tggccaacta atgcgcactc agaagccacc ttgcaaaaat   3600

gttaaatgga gcaaacgagt acacttgcaa gagtcctcca tatgtgggct taacatatgt   3660

accactccat tttagaaaaa tctcattaaa tgaattcttc taaaaaaaaa a            3711


<210>  852
<211>  1558
<212>  DNA
<213>  Human

<400>  852
gagtgcaaag cgctctccct ccctcgccca gccttcgtcc tcctggcccg ctcctctcat     60

ccctcccatt ctccatttcc cttccgttcc ctccctgtca gggcgtaatt gagtcaaagg    120

caggatcagg ttccccgcct tccagtccaa aaatcccgcc aagagagccc cagagcagag    180

gaaaatccaa agtggagaga ggggaagaaa gagaccagtg agtcatccgt ccagaaggcg    240

gggagagcag cagcggccca agcaggagct gcagcgagcc gggtacctgg actcagcggt    300

agcaacctcg ccccttgcaa caaaggcaga ctgagcgcca gagaggacgt ttccaactca    360

aaaatgcagg ctcaacagta ccagcagcag cgtcgaaaat ttgcagctgc cttcttggca    420

ttcattttca tactggcagc tgtggatact gctgaagcag ggaagaaaga gaaaccagaa    480

aaaaaagtga agaagtctga ctgtggagaa tggcagtgga gtgtgtgtgt gcccaccagt    540

ggagactgtg ggctgggcac acgggagggc actcggactg gagctgagtg caagcaaacc    600

atgaagaccc agagatgtaa gatcccctgc aactggaaga agcaatttgg cgcggagtgc    660

aaataccagt tccaggcctg gggagaatgt gacctgaaca cagccctgaa gaccagaact    720

ggaagtctga agcgagccct gcacaatgcc gaatgccaga agactgtcac catctccaag    780

ccctgtggca aactgaccaa gcccaaacct caagcagaat ctaagaagaa gaaaaaggaa    840

ggcaagaaac aggagaagat gctggattaa aagatgtcac ctgtggaaca taaaaaggac    900

atcagcaaac aggatcagtt aactattgca tttatatgta ccgtaggctt tgtattcaaa    960

aattatctat agctaagtac acaataagca aaaacaaaaa gaaaagaaaa tttttgtagt   1020

agcgtttttt aaatgtatac tatagtacca gtaggggctt ataataaagg actgtaatct   1080

tatttaggaa gttgacttat agtacatgat aaatgataga caattgaggt aagttttttg   1140

aaattatgtg acattttaca ttaaattttt tttacatttt ttgggcagca atttaaatgt   1200

tatgactatg taaactactt ctcttgttag gtaatttttt tcacctagat ttttttccca   1260

attgagaaaa atatatacta aacaaaatag caataaaaca taatcactct atttgaagaa   1320

aatatcttgt tttctgccaa tagatttttt aaaatgtagt cagcaaaatg ggggtgggga   1380

agcagagcat gtcctagttc aatgttgact tttttttttt ttaaagaaaa gcattaagac   1440

ataaaattct ttcactttgg cagaagcatt tgttttcttg atgaaattat ttttccatct   1500

gaggaaaaaa atactaggaa aataaatcaa ggtgatgctg aaaaaaaaaa aaaaaaaa     1558


<210>  853
<211>  2166
<212>  DNA
<213>  Human

<400>  853
agaattcttt ggcaggggcg accttagaat cctggggagg agcgagaatg gaatcccggg     60

gaggaacagg ggtggaatcc ggggggcggg gtcagaacgc caggaggggg cggggccgga    120

gccagggtcg gcttgactcg ggggagcagc gggtggatcc tgtgacgtca gcgggttcga    180

accgccggag ctgagcgaga ggccgggggt gccgagccgg gcggggagag ctgggccggg    240

agagcagaac agggaggcta gagcgcagcg ggaaccggcc cggagccgga gccggagccc    300

cacaggcacc tactaaaccg cccagccgat cggcccccac agagtggccc gcgggcctcc    360

ggccgggccc agtcccctcc cgggccctcc atggcccggg ccgctgccct cctgccgtcg    420

agatcgccgc cgacgccgct gctgtggccg ctgctgctgc tgctgctcct ggaaaccgga    480

gcccaggatg tgcgagttca agtgctaccc gaggtgcgag gccagctcgg gggcaccgtg    540

gagctgccgt gccacctgct gccacctgtt cctggactgt acatctccct ggtgacctgg    600

cagcgcccag atgcacctgc gaaccaccag aatgtggccg ccttccaccc taagatgggt    660

cccagcttcc ccagcccgaa gcctggcagc gagcggctgt ccttcgtctc tgccaagcag    720

agcactgggc aagacacaga ggcagagctc caggacgcca cgctggccct ccacgggctc    780

acggtggagg acgagggcaa ctacacttgc gagtttgcca ccttccccaa ggggtccgtc    840

cgagggatga cctggctcag agtcatagcc aagcccaaga accaagctga ggcccagaag    900

gtcacgttca gccaggaccc tacgacagtg gccctctgca tctccaaaga gggccgccca    960

cctgcccgga tctcctggct ctcatccctg gactgggaag ccaaagagac tcaggtgtca   1020

gggaccctgg ccggaactgt cactgtcacc agccgcttca ccttggtgcc ctcgggccga   1080

gcagatggtg tcacggtcac ctgcaaagtg gagcatgaga gcttcgagga accagccctg   1140

atacctgtga ccctctctgt acgctaccct cctgaagtgt ccatctccgg ctatgatgac   1200

aactggtacc tcggccgtac tgatgccacc ctgagctgtg acgtccgcag caacccagag   1260

cccacgggct atgactggag cacgacctca ggcaccttcc cgacctccgc agtggcccag   1320

ggctcccagc tggtcatcca cgcagtggac agtctgttca ataccacctt cgtctgcaca   1380

gtcaccaatg ccgtgggcat gggccgcgct gagcaggtca tctttgtccg agaaaccccc   1440

agggcctcgc cccgagatgt gggcccgctg gtgtgggggg ccgtgggggg gacactgctg   1500

gtgctgctgc ttctggctgg ggggtccttg gccttcatcc tgctgagggt gaggaggagg   1560

aggaagagcc ctggaggagc aggaggagga gccagtggcg acgggggatt ctacgatccg   1620

aaagctcagg tgttgggaaa tggggacccc gtcttctgga caccagtagt ccctggtccc   1680

atggaaccag atggcaagga tgaggaggag gaggaggagg aagagaaggc agagaaaggc   1740

ctcatgttgc ctccaccccc agcactcgag gatgacatgg agtcccagct ggacggctcc   1800

ctcatctcac ggcgggcagt ttatgtgtga cctggacaca gacagagaca gagccaggcc   1860

cggccctccc gcccccgacc tgaccacgcc ggcctagggt tccagactgg ttggacttgt   1920

tcgtctggac gacactggag tggaacactg cctcccactt tcttgggact tggagggagg   1980

tggaacagca cactggactt ctcccgtctc tagggctgca tggggagccc ggggagctga   2040

gtagtgggga tccagagagg acccccgccc ccagagactt ggttttggct ccagccttcc   2100

cctggccccg tgacactcag gagttaataa atgccttgga ggaaaacatc aaaaaaaaaa   2160

aaaaaa                                                              2166


<210>  854
<211>  2059
<212>  DNA
<213>  Human

<400>  854
agtcatttct tctgcggaac ctccacccct ccagtgggtg cgggacccta ggcagcaggc     60

caggcaccgc cgctctgact gggggccccg aagcagttaa cgggccggac agcaaagtgg    120

aaagttagac cagctgggac caggggaggt gggcacccgg ctgcgggagg agcggccagg    180

ctggcactgc ccccctaact tgctctcgat cctgccggtc tcgtcccgca gagccggtgc    240

catctgtggg ggctttgggc caggggtctc cggacagcat gagcgtgggc ttcatcggcg    300

ctggccagct ggcttttgcc ctggccaagg gcttcacagc agcaggcgtc ttggctgccc    360

acaagataat ggctagctcc ccagacatgg acctggccac agtttctgct ctcaggaaga    420

tgggggtgaa gttgacaccc cacaacaagg agacggtgca gcacagtgat gtgctcttcc    480

tggctgtgaa gccacacatc atccccttca tcctggatga aataggcgcc gacattgagg    540

acagacacat tgtggtgtcc tgcgcggccg gcgtcaccat cagctccatt gagaagaagc    600

tgtcagcgtt tcggccagcc cccagggtca tccgctgcat gaccaacact ccagtcgtgg    660

tgcgggaggg ggccaccgtg tatgccacag gcacgcacgc ccaggtggag gacgggaggc    720

tcatggagca gctgctgagc agcgtgggct tctgcacgga ggtggaagag gacctgattg    780

atgccgtcac ggggctcagt ggcagcggcc ccgcctacgc attcacagcc ctggatgccc    840

tggctgatgg gggtgtgaag atgggacttc caaggcgcct ggcagtccgc ctcggggccc    900

aggccctcct gggggctgcc aagatgctgc tgcactcaga acagcaccca ggccagctca    960

aggacaacgt cagctctcct ggtggggcca ccatccatgc cttgcatgtg ctggagagtg   1020

ggggcttccg ctccctgctc atcaacgctg tggaggcctc ctgcatccgc acacgggagc   1080

tgcagtccat ggctgaccag gagcaggtgt caccagccgc catcaagaag accatcctgg   1140

acaaggtgaa gctggactcc cctgcaggga ccgctctgtc gccttctggc cacaccaagc   1200

tgctcccccg cagcctggcc ccagcgggca aggattgaca cgtcctgcct gaccaccatc   1260

ctgccaccac cttctcttct cttgtcacta gggggactag ggggtcccca aagtggccca   1320

ctttctgtgg ctctgatcag cgcaggggcc agccagggac atagccaggg aggggccaca   1380

tcacttccca ctggaaatct ctgtggtctg caagtgcttc ccagcccaga acaggggtgg   1440

attccccaac ctcaacctcc tttcttctct gctcccaaac catgtcagga ccaccttcct   1500

ctagagctcg ggagcccgga gggtcttcac ccactcctac tccagtatca gctggcacgg   1560

gctccttcct gagagcaaag gtcaaggacc ccctctgtga aggctcagca gaggtgggat   1620

cccacgcccc ctcccggccc ctccctgccc tccattcagg gagaaacctc tccttcccgt   1680

gtgagaaggg ccagagggtc caggcatccc aagtccagcg tgaagggcca cagcccctct   1740

tggctgccaa gcacgcagat cccatggaca tttggggaaa gggctccttg ggctgctggt   1800

gaacttctgt ggccaccacc tcctgctcct gacctccctg ggagggtgct atcagttctg   1860

tcctggccct ttcagtttta taagttggtt tccagccccc agtgtcctga cttctgtctg   1920

ccacatgagg agggaggccc tgcctgtgtg ggagggtggt tactgtgggt ggaatagtgg   1980

aggccttcaa ctgattagac aaggcccgcc cacatcttgg agggcatctg ccttactgat   2040

taaaatgtca atgtaatct                                                2059


<210>  855
<211>  1979
<212>  DNA
<213>  Human

<400>  855
ggagcctgag ccctgcggaa cctcggcgct cggccccacc ccgcccgtac ctgcacttat     60

ttattgttgt tatttcttac cgcggagccc cgcagtcggg tcctcccgcc cgctcccgcg    120

cagcgctagc attctccagt ccctcagtcc cttcccgcgc ggtgcgccgc agccgaggcg    180

atgcgcctca ttcagaacat gtgcaccatc gccgagtacc ccgcgccggg caacgccgcg    240

gcctccgact gctgtgtggg cgccgccggc cgccgcctgg tcaagatcgc cgtggtgggc    300

gccagcggcg tgggcaagac cgcactggtg gtccggttcc tcaccaaacg attcatcggt    360

gactatgaaa gaaatgcagg taatctctat actagacaag ttcagataga aggtgaaacc    420

ctggctcttc aggttcaaga cactccaggt attcaggtcc atgagaacag cctgagctgc    480

agtgaacagc tgaataggtg cattcgctgg gcagatgctg tggtgatcgt tttctccatc    540

actgactaca agagctatga actcatcagc cagctccacc agcacgtgca gcagctacac    600

ctgggcaccc ggctgcctgt ggtggtcgtg gccaacaaag ctgacctgtt gcacatcaaa    660

caggttgacc ctcagcttgg actgcagcta gccagcatgc taggctgctc attctatgaa    720

gtgtctgtca gtgaaaatta taatgatgtc tacagcgcct tccacgtcct ctgtaaagag    780

gtcagtcaca aacagcagcc tagcagtaca cccgagaagc gaagaacctc cctcattccc    840

aggcccaagt cacccaacat gcaggacctg aagaggaggt ttaagcaagc cctctctgcc    900

aaagtgagga ctgtcacctc cgtctgaagc aggaggagca ctcaaggggg tttggtcttc    960

ccaggaagag ggcctgaggt tctcctagtg caggaacgtt gaatattggc aatgattcct   1020

ggttccagaa agggctggag cagaagggcc aagagggcct gtggaactgc tacagaaaag   1080

gaagtgttgt tctgagcagg gggacaggat tgatgaggct tgaaagagcc cactgagcca   1140

ctctctgaat atgtgaaatg tactctgtgt cttttccttt agagtgggga gggggcataa   1200

tcgtttcggt ttctgcattc aactaccttg taaatggtgg tccgttgcag tttcaccaaa   1260

tgtattgatg tgatttacag tgggaatgaa agaacagatt aagcattgat aggctttctt   1320

ttttccccct tttttctttt ttctcttttc ttctttcttt tcctcttttt ccccaagagg   1380

aagaattgct tttctcttac cagtatgatt tgtaactctg gaacactatt cttacagaat   1440

gcctttctaa cctgaaggat acccagattt ctttctttat gtacaagatg gaaaatcccc   1500

tacccctcaa aaacaggttg agtttatggg ccagaatatt ttgtatacca gacattggta   1560

agctctcatg gtttacagga aggctctggt tccccctcac aggatgagca tgctcagttg   1620

ggcgtgtgtg gaggagctgt gaacttcacg ctcttcaacc ccagactttg actgtatagt   1680

tttttgtttt tttaactgtt ccatcaggaa aaaaatgtgt cagttgattt tggtgtgact   1740

tgtgtaaatg gttcatggca atgacgttgg gttgcttcct aggcctggct gagttgtgcc   1800

taagggtggc tgaaatacta aaacacttat cttacagcaa gtgaacaggg gctacctgcc   1860

acatcccctc cacagatgca ctttaaaaag ccactcatgc tttggcttaa actgtaatta   1920

atttatttta tgtacaataa atcgcatttg aaaaagaaaa aaaaaaaaaa aaaaaaaaa    1979


<210>  856
<211>  1665
<212>  DNA
<213>  Human

<400>  856
gtgcgtgccg tgcgtgagcg tgcgcgggcg cgtcggccgg cgagggagca gcaaacggcc     60

ggcggcgggt gccgcgcggg gggcgggcgg cgcggagtag gtggcggcgg ccatggccga    120

ggcgtcgccg catcccggac ggtacttctg ccactgctgc tccgtggaga tcgtcccgcg    180

cctgccggat tatatctgtc caagatgcga gtctggtttt atcgaggagc ttccggaaga    240

gaccaggagc acagaaaatg gttctgcccc ctccacagct cccacagacc agagccggcc    300

accgttggag cacgtggacc agcacctgtt cacgctgccg cagggctacg gacagtttgc    360

tttcggcatc ttcgatgaca gcttcgagat ccccacgttc cctcctgggg cgcaggctga    420

cgacggcagg gaccctgaga gccggcggga gagagaccat ccgtcccggc accggtacgg    480

cgcccgacag ccccgcgccc gcctcaccac gcggcgggcc accggccggc acgaaggcgt    540

ccccacgctg gaagggatca tccagcagct cgtcaacggc atcatcacgc ccgccaccat    600

ccccagcctg ggcccctggg gagtcctgca ctcaaaccct atggactacg cctggggggc    660

caacggcctg gatgccatca tcacacagct cctcaatcag tttgaaaaca caggcccccc    720

accggcagat aaagagaaaa tccaggccct ccccaccgtc cccgtcactg aggagcacgt    780

aggctccggg ctcgagtgcc ctgtgtgcaa ggacgactac gcgctgggtg agcgtgtgcg    840

gcagctgccc tgcaaccacc tgttccacga cggctgcatc gtgccctggc tggagcagca    900

cgacagctgc cccgtctgcc gaaaaagcct cacgggacag aacacggcca cgaacccccc    960

tggcctcact ggggtgagct tctcctcctc gtcgtcatcg tcctcctcca gctcgcccag   1020

caacgagaac gccacaagca actcgtgagc ccacgtcggc cgtcgggaaa gcacggggcc   1080

tttcccaccc accctcagcc agcgccacac ggcacccaca gactgggtgc cccggcggcg   1140

ccacgcttgg ctggtcagcg ctgcaggtcc cgcctgttcc agggcaggac ccgggcccgg   1200

cccaccggcc ccctggcttg ggaaggcgtg ggccacatgg tcccctctgg ggcgtcccca   1260

gcctccccgt cctctgtcta acctcaccct ctaaacgttc agcggtggaa agatttttat   1320

aattttaaat tattactgct ttgaaataaa cggacgtttg agctcacgtg gcggccatgc   1380

atggtttgtg gcggaagacg gggcccagcg gctcccccag cgctgaagca cggggttcag   1440

cggctccccc agtgctgcag gtgccgccag gacgggccac gtgggccccc agcctccccc   1500

tcggccgcct ccacgacccg gagtaggggg gctcgggacc atgaggatga ccagcaaaat   1560

tcaagaacaa aactgctcca acagactttt ttaaaggaaa aaatatgtgt atcttgaaag   1620

ctatttaaaa tacactactt acaaagagaa aaaaaaaaaa aaaaa                   1665


<210>  857
<211>  1888
<212>  DNA
<213>  Human

<400>  857
ctacgatgac gtcagcgcgg cgcagtagcg gctgtgacta gcgggccggc ccgggccagg     60

acagcgggcg gcgggcggcg cgggcctggc cccgggatgg ctatgttccg cagcctggtg    120

gcctcggctc agcagcggca gccgccggcc gggccggcgg gcggcgacag cggcctggag    180

gcgcagtaca cctgccccat ctgcctggag gtctatcacc ggcccgtggc catcggcagc    240

tgcggccaca cgttctgcgg ggagtgtctc cagccctgcc tgcaggtgcc atccccgctg    300

tgcccactct gccgcctgcc cttcgacccc aagaaggtgg acaaggccac ccacgtggag    360

aagcagctct catcctacaa agcgccctgt cgaggctgca acaaaaaggt gaccctggca    420

aagatgagag tgcacatttc gtcctgcctg aaggtccagg agcagatggc caactgcccc    480

aagttcgtcc ccgtggtgcc cacatcacag cctatcccca gcaacatccc caacaggtcc    540

accttcgcct gcccgtactg tggtgcccgc aacctggacc agcaggagct ggtgaagcac    600

tgtgtggaaa gccaccgcag cgaccccaac cgcgtggtgt gccccatctg ctcggcaatg    660

ccctgggggg accccagcta caagagcgcc aacttcctgc agcacctgct tcaccgacac    720

aagttctcct acgacacctt tgtggactac agtattgacg aggaggccgc cttccaggct    780

gctctggccc tgtctctctc tgagaactga agggaagcgc agccacccgc ctgcgtctgg    840

ggtcagggat gtccccgctc ctgtgtcgca cctggcacct gctcgggagc gcacctcacc    900

ggactgagct cacaggagga gcctgcaccc gcgcagaagg ggagccgggg ccgagcctcc    960

gggcctgaat acgggccagc cgccgaggcc gccagagcag ggccgcctgg tcccaccggc   1020

gtcgctgggt tcttcggtgc ttctggccga gcaggcggcc tacttgggca gggctggacg   1080

ctgggacctg gagctgccgc cgtctcttca aagccatgat accccctcgt gggaagaagg   1140

gaccgacgcg cgagtcgcgc tccgcagtcg agccgggagg aacccaggct gctgccctgc   1200

ccagcccgac cctgccccgg ccccgcttcc accttgcgca tttggtactg gcttttgtga   1260

tacttaggaa ccctggcatc ttttctatat tatccagtgt gataatcttt tcacgtttta   1320

tagagcaaag acagagcagt tactcttcat attgcaatat ctgtgtttga ctaggaataa   1380

tagtattttt atggaacatt tacaaaatta tattttttaa gaaaacaatc aaaacaagca   1440

ttgggggatt ggggcaagga tggaaggagc agtggggcag ctgccagagc tcaggcgagc   1500

catggggtct gctgtggggt ctgccctggc cacccactgt gtgtctgggt ccttgaggtt   1560

tgtacgtttc tctttgatga ccaggaagaa atcccagcac cccagccaca ggctgtggct   1620

gctcccagca gaggcggggc cggcagagaa ggggcctcct ccacccagag tcctggcctt   1680

ggcccgctgt caccttcaaa gctgactgtg ccccgctgcg ggaggggacg gcaccccagt   1740

ggtggcagag cttgggggcc tgggcagggg cccgcttggc gggccgggca acacgtcaac   1800

attcttttct gttcttggca ttaattattg ctgtcttttt tttaaaaaaa aaagtttaaa   1860

taaaatgtct cagagcatct ctaaaaaa                                      1888


<210>  858
<211>  5639
<212>  DNA
<213>  Human

<400>  858
cttgcgcagg cgtagtgctc ctgcttcctg gccgagggcg ggcgagcgga gcctgctttc     60

gcagcgatcg cgagcgtgtg gcgattgctt ctgtctgtta tttagatatg gaagctgagg    120

ggatgcacag aggcagccag aacctaggtc agggtctcgc tcggtgctga ccgcccccgg    180

ggtcgagtag gcgatggggg agcccggctt cttcgtcaca ggagaccgcg ccggtggccg    240

gagctggtgc ctgcggcggg tggggatgag cgccgggtgg ctgctgctgg aagatgggtg    300

cgaggtgact gtaggacgag gatttggtgt cacataccaa ctggtatcaa aaatctgccc    360

cctgatgatt tctcgaaacc actgtgtttt gaagcagaat cctgagggcc aatggacaat    420

tatggacaac aagagtctaa atggtgtttg gctgaacaga gcgcgtctgg aacctttaag    480

ggtctattcc attcatcagg gagactacat ccaacttgga gtgcctctgg aaaataagga    540

gaatgcggag tatgaatatg aagttactga agaagactgg gagacaatat atccttgtct    600

ttccccaaag aatgaccaaa tgatagaaaa aaataaggaa ttgagaacta aaaggaaatt    660

cagtttggat gaattagcag gtcctggagc tgaaggcccc tcaaatttga aatccaaaat    720

aaataaagtg tcttgtgaat ctggtcagcc agtgaaatca caggggaaag gtgaagtggc    780

cagtacaccc tctgacaatt tggatcctaa gttgactgcc cttgagccaa gtaagaccac    840

aggggctccc atttaccctg gcttccccaa agtcacagag gttcatcatg agcagaaagc    900

ctcaaactct tcagcatctc agagaagctt acagatgttt aaggtgacca tgtccaggat    960

tctgaggctc aaaatacaga tgcaggaaaa acatgaagcc gttatgaatg tgaaaaagca   1020

gacccaaaag gggaactcaa agaaagttgt gcaaatggag caggaacttc aggacttaca   1080

gtcccagctg tgtgcagagc aggctcagca gcaggcaaga gtggagcaac tagagaagac   1140

tttccaggaa gaggaacagc atcttcaggg tttggagata gcccaaggag aaaaggacct   1200

gaagcaacag ctggcccagg ctctgcagga gcattgggct ctaatggaag agctaaatcg   1260

cagcaagaag gactttgaag caatcattca agccaagaac aaagaattag agcagaccaa   1320

ggaagagaag gagaagatgc aagcacagaa ggaagaagtt cttagccaca tgaatgatgt   1380

gctagagaat gagctccaat gtattatttg ttcagaatac ttcattgagg ctgtcacctt   1440

gaactgtgcc cacagtttct gctcctactg tatcaatgaa tggatgaagc ggaagataga   1500

atgccccatt tgtcggaagg acattaagtc caaaacgtac tctttggttc tggacaattg   1560

cattaataag atggtaaata atctgagctc agaagtgaaa gaacgacgaa ttgttctcat   1620

tagggaacga aaagcaaaga gattgttctg aagaccgtgc tctaagggca tttgaaagac   1680

tgccaggtag tgcgagcctg agatggtctg gaggattctc tctagccgtg actccgctgc   1740

tctgaaggtc aactgagaag tcttgtggga cagagacttg agttaggaag ccctcagtca   1800

cttgccttcc acggtggcca gccctgctgc catcattggc tgaagcacca ccaggattca   1860

cggcacccaa ctgcttcagg gtacttcgta gactctgcct cactacatgt cgaaagagtt   1920

atttgagttc tcttctgttt ttttttaatt tgttgttgtt gttactgttt tgatacctcg   1980

gaaacacctc cgttgacagt tgttttggat aggttgggtg taccccatgg ctgcctctga   2040

aggcagtgtc tattttgaga ggatggctta cctcttcttt gtgaaaatac tatctcattt   2100

cctggaaata aaatgtaaaa cctgtcagtt gctcagctgg gctttggtgt atttaccttc   2160

cttcccttcc tgctcccaga cagtctcaca agtaaacacc agcagctcat agattacaac   2220

caagaaagtg actgtatcag atgatagact tcaagtgaat gtcagcctaa gaggccaagc   2280

tgcagatcgt ggcaacagat gagctctgtt aacctcctga ctgtcgtgtt tcctttttat   2340

tacagaggtg ggtcactgtt taccttgttt caggggtggg agaaactcct ttccttcagc   2400

tggcatttga atgtttccaa atctatttta tctgacgtca tgaacacaca ggcaatgatt   2460

ttatgacaac ttgatgtgct tttttcttta tttttctttt acattagaag ttttctctct   2520

tttctccacc tctcctttat ttttaatttt aattttaatt tttgaaacaa gatctgactc   2580

tgttgcccaa gctggagtac agtagtgcaa tctcagctca ctgcaacctc cacctcccag   2640

actcaagcca tcctcccacc tcaacctccc aagtagctgg gactacaggc atatgccatc   2700

acacccagct aatttttgtt tttctgtaga gacagggttt caccatgttg gccaggctgg   2760

tctcaaattc ctgaccttaa gtgatccacc tgcctaggcc tctaaaatgc tgggattaca   2820

ggcgtgagcc accacgccca gcctataccc catgtatttt cataaagggt tggaaactat   2880

tgattgccaa ctttttaagg atggtaggga ttttttcttt gttgaatata ctgtgaattt   2940

tgggattctg gagtccttag tcttcatttc cattcttctg cccatgatta ctgatcaaaa   3000

tactggtaga gtcatggagg aagtaagtta aatgtggaaa aaatgcttta aaagtactta   3060

ctataaccac atcataagaa ttctggaaaa atagagaaca aaaggaaaag attgttacca   3120

ccttgattta ataacttctt gtttccccat acatgtgttt tgtttataga ttgcatgggt   3180

atatgtcaat ttttatatgt tctgtgttta gtttacatat tgtaattcat ttttaagaga   3240

gtacagacat acactttttg agtaggcaat atgttcacat agtttgaaat taaaggtaca   3300

aaatggcgta gaatgaaatg cctctcaccc tttccccaca gcgactactt cccactcaga   3360

ggcaacaagt attacagttg cttgtatatt cttccagaga tctctgtcta tacaagcaaa   3420

aacacatgtg gtctttttcc ttgctttgca caaatggtaa actgtacgct attctgaacc   3480

ttgctttttt cagatatatg ttggcaacag ttccatgtca gtacatagtt tcctttcttt   3540

attacagctg cctgtttttt cattgtgtat ttgcaccatc atttactttt ctggcttact   3600

tttgatagaa atctaggttg gttcaaacct ttttactctt aaaacaatgc tgcagttaac   3660

acccttgtac atatatcttt agagagaaga tattttaaaa agaaatacct ttttaaaaat   3720

tattttatta ttttttaata gagactatgt tgcctaggct ggtcttgaaa ttctgggcta   3780

aagcaatcct accaccttgg cctcccaaag tgctgagatt acaggcatga gccattgcac   3840

ctggccaaga agagacatct tgacttgagc ctgaagacta tgtacagaga ctgacctcac   3900

agactgacca ttccatccca cagctgctgg acatagagtg atttgcagcc cctcctttca   3960

gagtaccaca tccctctcaa gtgttccaca acatctagga aagtgagctc ttaaagacag   4020

actaaaaaga gtaataaatc aatacaacaa cattaaaagc cagactagcg gagtttgaat   4080

cttggccctg ctgttagtaa ctgtgtgagc cttgggcaag ttactcagcc tccttgtgtc   4140

ttggttttgg tttcttcatc tctaagtaat tatatctgtc attattgccc tgatcacaaa   4200

caaaagcctg aatgtactat gtttaaaaga caaaccaaaa attaacccaa acttgcatta   4260

tttgtctgag ctacagaatg ttctttcctt ggagagatat ctgatattaa acatcatctg   4320

cattttactt gcctagaaaa tacacggtaa cttttctgcc ttgcagcatc aaactatagt   4380

acagctgagc cccagtgctg tgcagtctga ctctaattaa aggcaccttc tttacagcag   4440

ggctctgggg aactggaaaa gggggtttgt ttcattatct ggttttatta agcagatgaa   4500

tgcagccagc tatatgaagc actttgcagt gaatggcagg tgtcccatat ctggttatgt   4560

taacctagaa agggctcact ctacctctag gcatgtttca tcccaacaat cagactgtgc   4620

caaagcaggg gactttgtcc tttgtggatt gcatagctgg atacccatca tctgtttctc   4680

tgattggaag ctgctgttgt acagaaagac ctgcatttcc cccttgtctc cagttctctc   4740

actacttttt cctcctctgt gagtgaccat ccaggcagtc accataactg ctggagtgtc   4800

tgggattggt agctctctcc aactgcctgc ttgctcttta cagcctctct ctgtgactgg   4860

aatctctcca cctcatcgta tctaaggata acccagaaac atggggtgtc ctaggtatgt   4920

ttatctcgac actgaacccc ctaggcttct gatgaatcca gtgattagct aaatttgaca   4980

tagaaagtaa gaaggaatgt ctactttgta ttgtggtcct aatctaagat caggagaatc   5040

ctggaattgt tatctgtctc ttgctctgag atacagactt gttcataggt gtggggcctg   5100

attggaacag gatctgccat tggtcacaat aggtcaaggg cttgttctga accctagtta   5160

gcttcattca gagaaagaaa cttcctacct ggtcagcttt ttcagcttct ccaacaaatg   5220

ggagttgagg cagtaggagt gtggggttct tgggaagacg atggggcctt gtattaagga   5280

gaaataatga actatcttct tgattcttcc attgagaaaa gcatatgaat cctaggaaag   5340

ggctcagcct gtgataggca ttcaataaat actccaatgc tgtcattcct ttgtctacag   5400

catccccaaa caatgtacca gtgatgggct acctgagctc atctagtcgc caagcagtat   5460

ctcctgcttg ctgctgcttt actacattcc agatgcccac ctcatccaat ttccagagcc   5520

actatctctg ctgtccactt tccttcaggc tctgtgaata cttcaacctg ctgtgatttg   5580

gggccgtttg tactctgcat gtattcaata aattcaattc agcaatagtt aaaaaaaaa    5639


<210>  859
<211>  8689
<212>  DNA
<213>  Human

<400>  859
ctcctctctt ttggaaaccg gagaggtgga gggagggcaa caccgctgca aaggagaggc     60

ccgccaagtc tgcccgcctg caaagtgttg ctttgacaca ttcttattat ggaagttaag    120

taaaaatata gacatattaa aaaataactc cggacgtgga gctgctacgg agaaggaaac    180

cgggggaaag aaaaccagta ggcaggccaa tggtttttcg gcagcgcgct ggcaagtttg    240

tggaacactt tctaggaatt aggtcttttc ctcccccttc atcatcttga cttctgaagg    300

aagaacttgg ctttggattg cagtggagcc taaggagaga gggttagaca cactcgaata    360

atccctctgg ctgggctgaa tttgtgggaa tttaggaagc cagagtgctg gaaatacagc    420

agcctttgaa gtaccctctg ttaatttgga tggatctcag tgtgccccgt tcgagacctc    480

tccaccaacc ccttctgatc ttgcgatttg ctcttcttga ctttaattag tatctaggaa    540

agtctaaact ttggacctac ctcttttttt gatactcatt tttgtacttt tgctctctgg    600

gattggtttc ttaaagaatc tggatccttt ttaatatgtc aaaatgagtc tgctgatgtt    660

tacacaacta ctgctctgtg gatttttata tgttcgggtt gatggatcgc gtcttcgcca    720

ggaggacttt cccccgcgga ttgtggagca tccttccgat gtcatcgtct ctaagggcga    780

gcccacgact ctgaactgca aggcggaggg ccggccaacg cccaccattg agtggtacaa    840

agatggggag cgagtggaga ctgacaagga cgatccccgg tcccacagga tgcttctgcc    900

cagcggatcc ttattcttct tgcgcatcgt gcacgggcgc aggagtaaac ctgatgaagg    960

aagctacgtt tgtgttgcga ggaactatct tggtgaagca gtgagtcgaa atgcgtctct   1020

ggaagtggca ttgttacgag atgacttccg acaaaacccc acagatgttg tagtggcagc   1080

tggagagcct gcaatcctgg agtgccagcc tccccgggga cacccagaac ccaccatcta   1140

ctggaaaaaa gacaaagttc gaattgatga caaggaagaa agaataagta tccgtggtgg   1200

aaaactgatg atctccaata ccaggaaaag tgatgcaggg atgtatactt gtgttggtac   1260

caatatggtg ggagaaaggg acagtgaccc agcagagctg actgtctttg aacgacccac   1320

atttctcagg aggccaatta accaggtggt actggaggaa gaagctgtag aatttcgttg   1380

tcaagtccaa ggagatcctc aaccaactgt gaggtggaaa aaggatgatg cagacttgcc   1440

aagaggaagg tatgacatca aagacgatta cacactaaga attaaaaaga ccatgagtac   1500

agatgaaggc acctatatgt gtattgctga gaatcgggtt ggaaaaatgg aagcctctgc   1560

tacactcacc gtccgagctc ccccacagtt tgtggttcgg ccaagagatc agattgttgc   1620

tcaaggtcga acagtgacat ttccctgtga aactaaagga aacccacagc cagctgtttt   1680

ttggcagaaa gaaggcagcc agaacctact tttcccaaac caaccccagc agcccaacag   1740

tagatgctca gtgtcaccaa ctggagacct cacaatcacc aacattcaac gttccgacgc   1800

gggttactac atctgccagg ctttaactgt ggcaggaagc attttagcaa aagctcaact   1860

ggaggttact gatgttttga cagatagacc tccacctata attctacaag gcccagccaa   1920

ccaaacgctg gcagtggatg gtacagcgtt actgaaatgt aaagccactg gtgatcctct   1980

tcctgtaatt agctggttaa aggagggatt tacttttccg ggtagagatc caagagcaac   2040

aattcaagag caaggcacac tgcagattaa gaatttacgg atttctgata ctggcactta   2100

tacttgtgtg gctacaagtt caagtggaga gacttcctgg agtgcagtgc tggatgtgac   2160

agagtctgga gcaacaatca gtaaaaacta tgatttaagt gacctgccag ggccaccatc   2220

caaaccgcag gtcactgatg ttactaagaa cagtgtcacc ttgtcctggc agccaggtac   2280

ccctggaacc cttccagcaa gtgcatatat cattgaggct ttcagccaat cagtgagcaa   2340

cagctggcag accgtggcaa accatgtaaa gaccaccctc tatactgtaa gaggactgcg   2400

gcccaataca atctacttat tcatggtcag agcgatcaac ccccaaggtc tcagtgaccc   2460

aagtcccatg tcagatcctg tgcgcacaca agatatcagc ccaccagcac aaggagtgga   2520

ccacaggcaa gtgcagaaag agctaggaga tgtccttgtc cgtcttcata atccagttgt   2580

gctgactccc accacggttc aggtcacatg gacggttgat cgccaacccc agtttatcca   2640

aggctaccga gtgatgtatc gtcagacttc aggtctgcag gcgacatctt cgtggcagaa   2700

tttagatgcc aaagtcccga ctgaacgaag tgctgtctta gtcaacctga aaaagggggt   2760

gacttatgaa attaaagtac ggccatattt taatgagttc caaggaatgg atagtgaatc   2820

taaaacggtt cgtactactg aagaagcccc aagtgcccca ccacagtctg tcactgtact   2880

gacagttgga agctacaata gcacaagtat tagtgtttcc tgggatcctc ctcctccaga   2940

tcaccagaat ggaattatcc aagaatacaa gatctggtgt ctaggaaatg aaacgcgatt   3000

ccatatcaac aaaactgtgg atgcagccat tcggtccgta ataattggtg gattattccc   3060

aggtattcaa taccgggtag aggttgcagc tagtaccagt gcaggggttg gagtaaagag   3120

tgagccacag ccaataataa tcgggagacg caatgaagtt gtcattactg aaaacaataa   3180

cagcataact gagcaaatca ctgatgtggt gaagcaacca gcctttatag ctggtattgg   3240

tggtgcctgc tgggtaattc tgatgggttt tagcatatgg ttgtattggc gaagaaagaa   3300

gaggaaggga ctcagtaatt atgctgttac gtttcaaaga ggagatggag gactaatgag   3360

caatggaagc cgtccaggtc ttctcaatgc tggtgatccc agctatccat ggcttgctga   3420

ttcttggcca gccacgagct tgccagtaaa taatagcaac agtggcccaa atgagattgg   3480

aaattttggc cgtggagatg tgctgccacc agttccaggc caaggggata aaacagcaac   3540

gatgctctca gatggagcca tttatagtag cattgacttc actaccaaaa ccagttacaa   3600

cagttccagc caaataacac aggctacccc atatgccacg acacagatct tgcattccaa   3660

cagcatacat gaattggctg tcgatctgcc tgatccacaa tggaaaagct caattcagca   3720

aaaaacagat ctgatgggat ttggttattc tctacctgat cagaacaaag gtaacaatgg   3780

tgggaaaggt ggaaaaaaga agaaaaataa aaactcttct aaaccacaga aaaacaatgg   3840

atccacttgg gccaatgtcc ctctacctcc ccccccagtc cagccccttc ctggcacgga   3900

gctggaacac tatgcagtgg aacaacaaga aaatggctat gacagtgata gctggtgccc   3960

accattgcca gtacaaactt acttacacca aggtctggaa gatgaactgg aagaagatga   4020

tgatagggtc ccaacacctc ctgttcgagg cgtggcttct tctcctgcta tctcctttgg   4080

acagcagtcc actgcaactc ttactccatc cccacgggaa gagatgcaac ccatgctgca   4140

ggctcacctg gatgagttga caagagccta tcagtttgat atagcaaaac aaacatggca   4200

cattcaaagc aataatcaac ctccacagcc tccagttcca ccgttaggtt atgtgtctgg   4260

agccttgatt tctgatttgg aaacggatgt tgcagatgat gatgccgacg acgaagagga   4320

agctttagaa atccccaggc ccctgagagc actggaccag actcctggat ccagcatgga   4380

caatctagac agctctgtga caggaaaagc ctttacctcc tctcaaagac ctcgacctac   4440

cagcccattt tctactgaca gtaacaccag tgcagccctg agtcaaagtc agaggcctcg   4500

gcccactaaa aaacacaagg gagggcggat ggaccaacaa ccagcattgc ctcatcgaag   4560

ggaaggaatg acagatgagg aggccttggt gccctatagc aagcccagtt tcccatctcc   4620

aggtggccac agctcatcag gaacagcttc ttctaaggga tccactggac ctaggaaaac   4680

cgaggtgttg agagcaggcc accagcgcaa tgccagcgac cttcttgaca taggatatat   4740

gggctccaac agtcaaggac agtttacagg tgaattatag taaatgagag gagacataca   4800

aagctgctct gaaggaccat caggtccgga ctcatggaag tgatgactct aaacagtgca   4860

atgaacaatt tatttatgta ctattaaaag aactgtaaat gcaatgtaaa gacacacagc   4920

cacacatatc ccacagatat tttcattgtg ttcttctctt aagtacacca cccaccttaa   4980

ctctttcttg tcaggagtat ataaaaaaga aagaaaacaa aactcgccct acaggaagaa   5040

aaggattctc ctctgtatat aatttctttt gtgcattgct atgcaagctc actcttttta   5100

gctctgctca tattattgtc tgttcttatt ggtctgttgt actatatgtg aattaatagg   5160

ctgtggtgcc atatattaac ttttaattgt gtaactttta tgtttaaatt ttgcactgca   5220

attttatttg gtgataagca caaatctcta ctcctcatga catgaagaaa aagactgaat   5280

gtgaagggag tttctgtact gtaagctaga ttggataatg atggctgtaa caaatcatgt   5340

tagatggttt tcagttgggg tgtagaaata ggaagatgca aaggaacaat ggtgttggca   5400

aagtcttctt tgaatatcag ggactgagtc aataaaaaaa atagtagaaa ggtggctttt   5460

actattgaca aaagccgggg tcaaaaaaag tagtttaagt cttaagactg aatatgcatt   5520

aaagtatgca ggtagcaaag atgtaataaa tttgcttaaa aaaagaaatt aaagttttat   5580

ttagaatcaa ttttacctgt cattgtaatt gacccatctg agaattacaa taagcaagag   5640

gaaattaagg tgttttgcaa gagctgtatt tatattacag ttttttaaaa acattttctg   5700

aattatcgta attaagctct ccaactcgtt aagtcagaat ataatatgaa gttccccaag   5760

gaaacgaaca aaatgaactc tagaatatct agcaaatagt taaagaagca atttattatt   5820

agggcatact cgggctgttt ccaaatataa actctattgc aatatcttat ttcatctttc   5880

taatacatgt acagtgcaca ctagaggata gagctgcatc acttaaattc atgacttaaa   5940

aaataataca gtttatatac aacttgtttt ttatttgatt aagaagtgaa gtttacgcca   6000

cccaatgtat agccaaattg tacgtgctta aaaaacagtg ccgagagtat gttcagttcg   6060

cagtaagtag atttattgga ataaatattc tatggtacat tctcagaaat tggcttccaa   6120

ctaaaatacg tttgacccat tttgaataag gaaattgaaa agaaaaattt aaaaggagaa   6180

aaaaatgcat gtttataaac tttttaaata aaaccagacc ttgtaagtgg acattaataa   6240

ttgtcctgcc tcatttgttt tcacgacttt gacaacaaga agttcctgaa cattagtcat   6300

gtatgctcag aataaatgtg actttgaaat atatgttagc tactgtacat gtatagtcag   6360

tcaagtagaa gaggaccttc ctgaaattcc cacttgtgac attttcccat gggtttccta   6420

cacaatctta aattttattt ctgtctatac tttctcaaat ttttcctatg ataagttcag   6480

ttgttggtac tcttctaaaa atattcaacg tgattaggat cagttctaaa atacgggacc   6540

cctttgagtg acaattcgca ctccatgcat tattggctca gtagccaatt tttgtcacgt   6600

cgttataaca aggagatgac ataattaaac atttccatcc tttctattcc ctgagactgc   6660

atcagcacag gcaagtatag aatgtaatgt tcttcatggg ccccaccagc tttttggtgc   6720

catgtaattt atttcttcgc tgaagagaaa aagaattctg agacacagtt attaaaccct   6780

ttatcaactt tctaccatca gtgcctgaat tctaatgcag tgtgatttct ctgggacaaa   6840

gagactgagg aagatgaaaa gtttcttcaa agagtgaata catacttatt cacaactcta   6900

ggatgtgagg actttaaata tctctttatg aagttccctg cctaacctct ttctatttaa   6960

aggcaaacaa atttcgaaga ggttttgtgt tccctcttta tgtttctcta tgacccagtt   7020

tagtctaaaa ccttagttca ttacatatac aacacatagc ctttgatccc tggtaactgg   7080

caggtgttgg tgattaataa accaaggctt caaagtgaag tatgtgtgtg cagatgactt   7140

ttggaataac gtgggcatag catcatacct tcctgattgt cttcagcata taaaaattaa   7200

ctgttgtagt taaaattatg tcagtgcaga gcttgtggtt acttggaatg ttctttcaga   7260

atagtccatg ttgcctatta aacctagttt taaacacatt gggcagtcaa tttatgcacc   7320

caaaatatca ccctcaggta gattgagggc aagataaaat gctgtatgta gctatacaaa   7380

ggaattcaga aacattactg gaaagcaaag cctttgtcag cttgctactg acaaagtagt   7440

aaaaagctac taatcagtgt tgagtcagat gtcaacagaa aaatacaaat acctatgaga   7500

gccacagcag tttctcgttt catagccgat tcaatgaata tgattagaaa ttcactgagc   7560

tcactcttgc aggtttaaat ggaggcctgc ataaggactg caagaggaaa tctgggtggg   7620

agagaatgta atctgatctt gcactcatag gcaatgctgc aatgcaatca tgtccaatac   7680

aagcacagct tcattcataa caggaaacgt cttctttggg aaaatagctc tattggtgcc   7740

caaactcagg tatgccagtg tatgcaggtg gagtcgccct acccctcttc caaacatgtc   7800

ctgtgagatt tttaaaataa gatgggatag tacaggggca tgaaaagaat tgattccttc   7860

acaggatttg aatccagttc aagggagaat gtagaaaatt caaaaccaac atataaggta   7920

tcacacaacc aagaaaagta aaaccattgc aagtttactt gcgttgagta caaaacagat   7980

ttaatggtgt tctatgtcat agtttaatgc tctgggtatt taaatatgtt ttcaacagga   8040

tttgagttga aagtttgtaa tgtgctttga tggaacacct ctcaatttct attcaataaa   8100

cttatgtaat tgtccattga caatataatg ataacagtac cattgaactc taaactgtgg   8160

tttatcttca ctactgggaa gcaactgtgc atcagtatta aagatatgca gaaacataat   8220

attcactaat ttgttcatct gcttctgtat attgtttatg gaattacatg gcaagaactg   8280

ttctaaagca acatgtcttt ccacattatt ttagaggtga aattactttt gttttgcttc   8340

tctataatgt gtacttcaaa tgaaacacca tacttttttc taaaaaaaga tgttcaattt   8400

actaattttt ttaaatctca taatttaaaa agcatttgtt gtgattttaa agtgttgcaa   8460

gaaaagggat tttgtggccg tgggtagact ttttatactt tgttttatag atggattttt   8520

tttaactgta gtttgtttaa gtcaccaagc agcatccaaa atcttaatgt gtttcatttg   8580

atgttgttag atcagagaag aaattggcat aaaatcggtt aatagtattg tcaaagaatt   8640

gtgtattgtg tactcactgg gaaaaaataa aatatattca catttcaaa               8689


<210>  860
<211>  4554
<212>  DNA
<213>  Human

<400>  860
gagggcacga agaggcaccg accgtaccca ggcgcaccgg caggagagcg gcaccgtggc     60

tgccgcagcg cgcagaggct gtggaggggc ttacggctcc cagcccacgg gtctcagacc    120

caggggctgg gcccccagcc cccagtcccg atcccagctg ggtcgagcca tgctgcgcta    180

cctgctgaaa acgctgctgc agatgaactt gttcgcggac tctctggccg gggacatctc    240

caactccagc gagctgctct tgggcttcaa ctcctcgctg gcggcgctca accacaccct    300

gctgcctccc ggcgatccct ctctcaacgg gtcaagggta ggaccggagg acgctatgcc    360

ccgcatcgtg gagcagccgc cagatctgct ggtctcccga ggcgagcccg ccacgttgcc    420

ctgccgcgct gaaggccgac cccgacccaa cattgagtgg tacaagaacg gggcgcgtgt    480

ggccactgtg cgggaggatc cgcgtgcgca ccgcctgctg ctgcccagcg gcgccctctt    540

cttcccgcgc atcgtgcacg ggcgccgcgc gcggccggac gaaggtgtct acacttgcgt    600

ggctcgcaac tacctggggg cagcagcgag cagaaacgcc tcgctggaag tggcagtcct    660

ccgtgatgat ttccggcagt ctcctggaaa cgtggtggtg gcagtggggg agccagcagt    720

actggaatgc gtgccccccc gcggccaccc ggagccttcc gtgtcctgga ggaaggacgg    780

tgcaagactc aaggaagagg aaggaaggat cacgatccgt ggagggaagc tgatgatgtc    840

acatacactc aagagcgatg caggcatgta tgtgtgcgta gcctccaaca tggcgggaga    900

acgggagagt gcggcagctg aagtcatggt actggagcgt ccctcattcc tgcgcagacc    960

agtgaatcag gtggtcctgg ctgatgcccc tgtgactttc ctatgtgagg tgaaggggga   1020

tcccccacct cgtctacgct ggcgcaagga ggatggggaa ctgcccacag gcaggtatga   1080

gatccggagt gaccacagcc tttggattgg gcatgtgagt gccgaagatg agggaacgta   1140

cacctgtgtg gcggagaaca gtgtgggccg cgctgaagca tctggctccc tcagtgttca   1200

cgtcccaccc cagttggtga cccagcccca ggaccagatg gcagctcctg gagagagcgt   1260

ggctttccag tgcgagacca aaggaaaccc cccacctgcc atcttctggc agaaggaggg   1320

gagtcaggtc ctgcttttcc ccagtcagtc acttcagccg acggggcgct tctcagtgtc   1380

tccaagaggc caacttaaca tcaccgcggt gcagcgtggg gatgctgggt actacgtgtg   1440

ccaggctgtc agtgtggctg gcagcatcct ggccaaggcc ctgctggaga taaaaggagc   1500

ctctttggat gggctgcctc ctgtcatcct ccagggacca gccaatcaga cgctggtgct   1560

tggctcctcc gtgtggctgc cctgcagagt gactgggaac cctcaaccca gtgtccgatg   1620

gaagaaggat gggcagtggc tgcaggggga tgacctccag ttcaagacaa tggccaacgg   1680

taccctgtac atcgccaatg tgcaggagat ggacatgggc ttctacagct gcgtggccaa   1740

gagttccaca ggggaagcca catggagcgg ctggcttaag atgcgggaag actggggagt   1800

atcaccagac ccccctacag aacccagttc ccctccgggg gctccctctc agccagtggt   1860

cactgagatc accaagaaca gcattaccct gacctggaag cccaacccac aaactggggc   1920

tgcagtcacg tcttatgtga tagaggcctt cagcccagca gctggcaaca catggcgtac   1980

tgtggcagat ggcgtgcagc tggagacaca cacagtcagc ggtctgcagc ccaataccat   2040

ctacctgttt ctggttcgag cagtgggagc ctggggcctc agtgagccca gccccgtctc   2100

tgagcctgtc cgtacacagg atagcagccc ctctaggcca gtggaggacc catggagagg   2160

ccagcaggga ctggcggaag tggctgtgcg cctgcaggag cccatagtcc tgggaccccg   2220

gaccctgcag gtgtcctgga ctgtggatgg cccagtccag ctggtgcaag gtttccgggt   2280

gtcttggagg gtagcaggcc ctgagggagg aagctggaca atgttggacc tacagtcccc   2340

aagccagcaa agtactgtgc taagaggact ccctccaggg acccaaatcc agatcaaggt   2400

gcaagcccaa ggccaggagg ggctgggggc tgaaagcctc tctgtgacca ggagcattcc   2460

tgaggaggcc cccagtggcc ccccacaggg agtggcggtg gccttggggg gtgatggcaa   2520

cagcagtatc actgtgtcct gggaacctcc actcccctcc cagcaaaatg gggtcatcac   2580

ggaataccag atctggtgcc tgggcaatga gagccgcttt cacctcaatc gatctgcagc   2640

aggctgggca cgctccgcaa tgctccgagg actggtgccc ggtctcctct atcgaaccct   2700

ggtcgcggcg gccaccagcg caggcgtggg cgtgcccagt gccccagtgc tggtgcagct   2760

gccgtccccg ccggacctgg agcccgggct ggaggtgggc gcggggctgg cggtgcggct   2820

ggcgagggtg ctgcgggagc ccgccttcct cgcgggcagc ggcgcagcct gcggggcgct   2880

gcttctcggg ctctgcgccg ccctctactg gcgccggaaa cagcgcaaag agctcagcca   2940

ctacacggcc tcttttgcct acacaccggc agtgtccttc ccgcactcag agggcctctc   3000

tggagccagt tccaggccac ccatgggcct tggccccgcc ccctactcat ggctggcaga   3060

ttcgtggccc cacccatctc gaagcccctc ggcccaggaa cccaggggaa gctgctgccc   3120

tagcaatcct gacccggacg acagatatta caacgaagcg ggaatctccc tgtatctagc   3180

tcagacggcc aggggcacgg ccgcccctgg cgagggtcct gtctatagca ccattgaccc   3240

agcgggggag gagctgcaga ccttccatgg gggcttcccc caacatccct caggagatct   3300

gggtccctgg agccagtacg ctcctccaga gtggagccag ggggacagtg gagccaaggg   3360

aggcaaagtg aagcttctgg ggaaacctgt gcagatgccc tctctgaact ggccagaagc   3420

cctgccccca cctcctcctt cttgtgaact gagctgccta gaagggccgg aggaggagct   3480

ggagggcagc tcagagccag aggagtggtg cccgccaatg cctgagagaa gtcacctgac   3540

ggagcccagc tccagtggag ggtgcctggt caccccatcc cgaagggaaa ccccctctcc   3600

cacaccttcc tatggacagc agtccacagc cactcttaca ccctcacctc ctgaccctcc   3660

ccagccccca actgacatgc cccatctcca tcagatgccc aggagggtgc cccttgggcc   3720

gagttcccct ctcagtgtat cccagcccat gctgggcatc cgtgaagcga ggcctgctgg   3780

cttgggtgct ggccctgcag cctcacccca cctcagcccc agtcctgccc ctagcacagc   3840

cagcagtgcc ccaggcagaa cctggcaggg gaatggggag atgactcccc cacttcaagg   3900

accccgtgct cgattccgga agaaacccaa ggctcttccc tacaggaggg agaacagtcc   3960

tggggacttg cccccaccac ccttgccacc gccagaggaa gaggcgagct gggccctaga   4020

gctgagggca gcaggcagca tgtcctccct ggagcgggag cgcagtgggg agaggaaagc   4080

ggtccaggcc gtgcccctgg cagcccagcg ggtgctccac ccagatgaag aggcctggct   4140

cccatacagc agaccaagct tcctgtcccg gggccagggc accagcacat gttccacggc   4200

cggcagcaac tcttccaggg gctccagcag ctctaggggc tcccggggcc ctggccggag   4260

ccggagtcgg agtcagagcc ggagccagag ccaaaggcca ggacagaaac gccgagagga   4320

accaagatga cccttgttgg ggcattgaga atatcatgag tgccacgggg aaggggagta   4380

gggatgtctt ttccccccca gcagtgatga gtggggctag ctgaagccca ttggtttcca   4440

cgatttcaat tggctgagaa ggcagagagc tagctcctcc ctttctttct ttttccacct   4500

gagacttgtt tataaaaaac aaaacaataa aaagagtctg atcagagccc aggg         4554


<210>  861
<211>  719
<212>  DNA
<213>  Human

<400>  861
agtctctttt ccggttagcg cggcgtgaga agccatgagc agcaaagtct ctcgcgacac     60

cctgtacgag gcggtgcggg aagtcctgca cgggaaccag cgcaagcgcc gcaagttcct    120

ggagacggtg gagttgcaga tcagcttgaa gaactatgat ccccagaagg acaagcgctt    180

ctcgggcacc gtcaggctta agtccactcc ccgccctaag ttctctgtgt gtgtcctggg    240

ggaccagcag cactgtgacg aggctaaggc cgtggatatc ccccacatgg acatcgaggc    300

gctgaaaaaa ctcaacaaga ataaaaaact ggtcaagaag ctggccaaga agtatgatgc    360

gtttttggcc tcagagtctc tgatcaagca gattccacga atcctcggcc caggtttaaa    420

taaggcagga aagttccctt ccctgctcac acacaacgaa aacatggtgg ccaaagtgga    480

tgaggtgaag tccacaatca agttccaaat gaagaaggtg ttatgtctgg ctgtagctgt    540

tggtcacgtg aagatgacag acgatgagct tgtgtataac attcacctgg ctgtcaactt    600

cttggtgtca ttgctcaaga aaaactggca gaatgtccgg gccttatata tcaagagcac    660

catgggcaag ccccagcgcc tatattaagg cacatttgaa taaattctat taccagttc     719


<210>  862
<211>  579
<212>  DNA
<213>  Human

<400>  862
tctttctttt cgccatcttt tgtctttccg tggagctgtc gccatgaagg tcgagctgtg     60

cagttttagc gggtacaaga tctaccccgg acacgggagg cgctacgcca ggaccgacgg    120

gaaggttttc cagtttctta atgcgaaatg cgagtcggct ttcctttcca agaggaatcc    180

tcggcagata aactggactg tcctctacag aaggaagcac aaaaagggac agtcggaaga    240

aattcaaaag aaaagaaccc gccgagcagt caaattccag agggccatta ctggtgcatc    300

tcttgctgat ataatggcca agaggaatca gaaacctgaa gttagaaagg ctcaacgaga    360

acaagctatc agggctgcta aggaagcaaa aaaggctaag caagcatcta aaaagactgc    420

aatggctgct gctaaggcac ctacaaaggc agcacctaag caaaagattg tgaagcctgt    480

gaaagtttca gctccccgag ttggtggaaa acgctaaact ggcagattag atttttaaat    540

aaagattgga ttataactct agaaaaaaaa aaaaaaaaa                           579


<210>  863
<211>  1580
<212>  DNA
<213>  Human

<400>  863
ccttgtcctg cccagatctt gtcccttcta gtactggcct tccccattcc tgggggcccc     60

cgcccctccg acccccgccg accggcgctg gactacaact cccggcgtgc cgcgcgcgtc    120

cggccggctg caccggggct ttgcgcgtgg cggccgccga gctccgcgcg gggcaaacct    180

cccggcgcgg ccatgcgggg agttgctgaa gtaaaggaac cctgcagcct tcccatgcta    240

tctgttgaca tggaaaacaa ggaaaatggc tctgtcggtg taaaaaattc catggaaaat    300

gggagaccac ctgatcctgc agactgggcc gtgatggatg tcgtcaatta tttccgaacc    360

gtgggatttg aggagcaagc tagtgctttt caggaacagg aaattgatgg aaaatccctg    420

ctattgatga caagaaatga tgtgttgaca ggacttcagt taaaattggg gcctgctctg    480

aaaatctacg aatatcatgt aaaacctctg cagacaaagc atttaaagaa caactcttca    540

tagtacagtc aaattggggt cttcgacctc aaaaaataca taatgacata atttagtttc    600

atgtaatgaa actttgtaaa cagaatacat acatgtgtat atgtaaagaa tttcaatcaa    660

atgaaacgtt atcctattgg atagactagg caattcatca gctcacctga aatcagccag    720

gaggagcaag gacaagatgc gcacagggtg gttttcctca tggattttgt caaatagatg    780

atctttgaca cgattagaca ctcctcccca caaaggcttt gaaatcataa ggattttcct    840

catctcttta tagctttccc aaaatctttt aaaaaagaat ttaattaaat gacagtcttt    900

tggttacaga cttaggatga gtaaaaacaa gaaaatttgg ggagggggag aaagaagaaa    960

gggattgctg tctcccttga attcctctgt tccttagagc ttgtgttact tggacggaat   1020

tgccaacacc cttttttata gagggttctc cacttgacct tattaaggtt ttattgggat   1080

atgctgcagt gtttgaaatg aacatgcatc atggcccctt caggagcaga atcatagctc   1140

tgaaaagaga agctccgttg tgtactgagg atatccatcc atattcagct agctttcaaa   1200

tggggtaatg atattttctg catagatttt cttttaaatt ggttctttgt ttctgaagaa   1260

agaatttttt ttaacttcat ggttttattt ataataattt gtttctgaag aaatttgccg   1320

agagttacag gtcaaaaagc cttgttacta gtacagaata tttttatata tattccttca   1380

tgatggtgta atttttttta attgtcctat gctttgttcg gttcctgggt taagtacttg   1440

tttttaagag cttggaaaaa gtgggcttgc tacatctctg ttcaaagaga catttgttca   1500

atctctgtgt gtcaacgcct tgttgaattg gtgctttgtg gttgcaataa agcattgctt   1560

cagtttaaaa aaaaaaaaaa                                               1580


<210>  864
<211>  2928
<212>  DNA
<213>  Human

<400>  864
tgtcccgttt ccggacccgt ctctatggtg taggagaaac ccggccccca gaagattgtg     60

ggtgtagtgg ccacagcctt acaggcaggc aggggtggtt ggtgtcaaca ggggggccaa    120

cagggtacca gagccaagac cctcggcctc ctcccccgcc gccttcctgc agatctgctt    180

ggctttgagg aagagtggca gtactgcctc actgcataag ggatgggatc agagaacagt    240

gctttaaaga gctatacact gagagaacca ccatttacct taccctctgg acttgctgtt    300

tatcccgctg tactgcaaga tggcaaattt gcttcagttt ttgtgtataa gagagaaaat    360

gaagacaagg ttaataaagc tgccaagcat ttgaagacac ttcgtcaccc ttgcttgcta    420

agatttttat cttgtactgt ggaagcggat ggcattcatc ttgtcactga gcgagtacag    480

cccctggaag tggctttgga aacattgtct tctgcagagg tctgtgctgg gatctatgac    540

atattgctgg ctcttatctt ccttcatgac agaggacacc taacacacaa taatgtctgt    600

ttatcatctg tgtttgtgag tgaagatgga cactggaagc taggaggaat ggaaactgtt    660

tgtaaagttt ctcaggccac accagagttt ctgaggagta ttcagtcaat aagagaccca    720

gcatctatcc ctcctgaaga gatgtctcca gaattcacaa ctctcccaga gtgtcatgga    780

catgcccggg atgccttttc atttggaaca ttggtggaaa gtttgctcac aatcttaaat    840

gaacaggttt cagcggatgt tctctccagc tttcaacaga ccttgcactc aactttgctg    900

aatcccattc caaaatgtcg gccagcgctc tgcaccttac tatctcatga cttcttcaga    960

aatgattttc tggaagttgt gaatttcttg aaaagtttaa cattgaagag tgaagaggag   1020

aaaacggaat tctttaaatt tctgctggac agagtcagct gcttgtcaga ggaattgata   1080

gcttcaaggt tggtgcctct tctgcttaat cagttggtgt ttgcagagcc agtggctgtt   1140

aagagttttc ttccttatct gcttggcccc aaaaaagatc atgcgcaggg agaaactcct   1200

tgcttgctct caccagccct gttccagtca cgggtgatcc ccgtgcttct ccagttgttt   1260

gaagttcatg aagagcatgt gcggatggtg ctgctgtctc acatcgaggc ctacgtggag   1320

cacttcactc aggagcagct gaagaaagtc atcttgccac aggttttgct gggcctgcgt   1380

gatactagcg attccattgt ggcaattact ctgcatagcc tagcagtgct ggtctctctg   1440

cttggaccag aggtggttgt gggaggagaa cgaaccaaga tcttcaaacg cactgcccca   1500

agttttacta aaaatactga cctttctcta gaaggcgatc cattttctca gcctattaaa   1560

tttcccataa atggactctc agatgtaaaa aatacttcgg aggacagtga aaacttccca   1620

tcaagttcta aaaagtctga ggagtggcct gactggagtg aacctgagga gcctgaaaat   1680

caaactgtca acatacagat ttggcctaga gaaccttgtg atgatgtcaa gtcccagtgc   1740

actaccttgg atgtggaaga gtcatcttgg gatgactgcg agcccagcag cttagatact   1800

aaagtaaacc caggaggtgg aatcactgct acaaaacctg ttacctcagg ggagcagaag   1860

cctattcctg ctttgctttc actcactgaa gagtctatgc cttggaaatc aagcttaccc   1920

caaaagatta gccttgtaca aaggggggat gacgcagacc aaatcgagcc gccaaaagtg   1980

tcatcacaag aaaggcccct taaggttcca tcagaacttg gtttaggaga ggaattcacc   2040

attcaagtaa aaaagaagcc agtaaaagat cctgagatgg attggtttgc tgatatgatc   2100

ccagaaatta agccttctgc tgcttttctt atattacctg aactgaggac agaaatggtc   2160

ccaaaaaagg atgatgtctc cccagtgatg cagttttcct caaaatttgc tgcagcagaa   2220

attactgagg gagaggctga aggctgggaa gaagaagggg agctgaactg ggaagataat   2280

aactggtgac aatagatgtg agttaaactt taggaaaaag gattcccttt ttttaaaaaa   2340

aatcaatacc tcaaaagcag gctttgggac aagaaaaccc caaagtggcc tgcttttccc   2400

atcccaggag ctcattatcc agtctgtgcc aactgaagta ggagactgac tgtgagtgct   2460

ggctaaaagc cctgggtggt gaggctcaca gtactggttt ccaggaggaa gagcctttgt   2520

gcatttgact gaggccagtt tctatgaaga gcaagtagct gaggagaggt cgaatttact   2580

gctttttcca ggacaattct ggaagtaaag aaaatgtaat tcaagctggt tagcttaatt   2640

ttgtgccatt ctttaacata agagtaagct ctattatgaa atacaacttt aaaaaatttt   2700

agctataaat tatataaatg attttaaatt gctgaggttt ccttaggcag cttatttatt   2760

tgtttacagt tagactatct gagtaaatgg ttctttgtgg acctaggcag ttcctgactg   2820

ttccacatgt agtacattgt accaaagttc ttaataagaa tattccccac aatcctgttc   2880

tctaaatgtc aaataaagat tattttcact agattcaact ttacaaaa                2928


<210>  865
<211>  3217
<212>  DNA
<213>  Human

<400>  865
ggccgggaga cctggcggag ctgggggtgg ggggccagtt tttgcaacgg ctaaggaagg     60

gcctgtgggt ttattataag gcggagctcg gcgggagagg tgcgggccga atccgagccg    120

agcggagagg aatccggcag tagagagcgg actccagccg gcggaccctg cagccctcgc    180

ctgggacagc ggcgcgctgg gcaggcgccc aagagagcat cgagcagcgg aacccgcgaa    240

gccggcccgc agccgcgacc cgcgcagcct gccgctctcc cgccgccggt ccgggcagca    300

tgaggcgcgc ggcgctctgg ctctggctgt gcgcgctggc gctgagcctg cagccggccc    360

tgccgcaaat tgtggctact aatttgcccc ctgaagatca agatggctct ggggatgact    420

ctgacaactt ctccggctca ggtgcaggtg ctttgcaaga tatcaccttg tcacagcaga    480

ccccctccac ttggaaggac acgcagctcc tgacggctat tcccacgtct ccagaaccca    540

ccggcctgga ggctacagct gcctccacct ccaccctgcc ggctggagag gggcccaagg    600

agggagaggc tgtagtcctg ccagaagtgg agcctggcct caccgcccgg gagcaggagg    660

ccaccccccg acccagggag accacacagc tcccgaccac tcatcaggcc tcaacgacca    720

cagccaccac ggcccaggag cccgccacct cccaccccca cagggacatg cagcctggcc    780

accatgagac ctcaacccct gcaggaccca gccaagctga ccttcacact ccccacacag    840

aggatggagg tccttctgcc accgagaggg ctgctgagga tggagcctcc agtcagctcc    900

cagcagcaga gggctctggg gagcaggact tcacctttga aacctcgggg gagaatacgg    960

ctgtagtggc cgtggagcct gaccgccgga accagtcccc agtggatcag ggggccacgg   1020

gggcctcaca gggcctcctg gacaggaaag aggtgctggg aggggtcatt gccggaggcc   1080

tcgtggggct catctttgct gtgtgcctgg tgggtttcat gctgtaccgc atgaagaaga   1140

aggacgaagg cagctactcc ttggaggagc cgaaacaagc caacggcggg gcctaccaga   1200

agcccaccaa acaggaggaa ttctatgcct gacgcgggag ccatgcgccc cctccgccct   1260

gccactcact aggcccccac ttgcctcttc cttgaagaac tgcaggccct ggcctcccct   1320

gccaccaggc cacctcccca gcattccagc ccctctggtc gctcctgccc acggagtcgt   1380

ggggtgtgct gggagctcca ctctgcttct ctgacttctg cctggagact tagggcacca   1440

ggggtttctc gcataggacc tttccaccac agccagcacc tggcatcgca ccattctgac   1500

tcggtttctc caaactgaag cagcctctcc ccaggtccag ctctggaggg gagggggatc   1560

cgactgcttt ggacctaaat ggcctcatgt ggctggaaga tcctgcgggt ggggcttggg   1620

gctcacacac ctgtagcact tactggtagg accaagcatc ttgggggggt ggccgctgag   1680

tggcagggga caggagtcca ctttgtttcg tggggaggtc taatctagat atcgacttgt   1740

ttttgcacat gtttcctcta gttctttgtt catagcccag tagaccttgt tacttctgag   1800

gtaagttaag taagttgatt cggtatcccc ccatcttgct tccctaatct atggtcggga   1860

gacagcatca gggttaagaa gacttttttt tttttttttt aaactaggag aaccaaatct   1920

ggaagccaaa atgtaggctt agtttgtgtg ttgtctcttg agtttgtcgc tcatgtgtgc   1980

aacagggtat ggactatctg tctggtggcc ccgtttctgg tggtctgttg gcaggctggc   2040

cagtccaggc tgccgtgggg ccgccgcctc tttcaagcag tcgtgcctgt gtccatgcgc   2100

tcagggccat gctgaggcct gggccgctgc cacgttggag aagcccgtgt gagaagtgaa   2160

tgctgggact cagccttcag acagagagga ctgtagggag ggcggcaggg gcctggagat   2220

cctcctgcag accacgcccg tcctgcctgt ggcgccgtct ccaggggctg cttcctcctg   2280

gaaattgacg aggggtgtct tgggcagagc tggctctgag cgcctccatc caaggccagg   2340

ttctccgtta gctcctgtgg ccccaccctg ggccctgggc tggaatcagg aatattttcc   2400

aaagagtgat agtcttttgc ttttggcaaa actctactta atccaatggg tttttccctg   2460

tacagtagat tttccaaatg taataaactt taatataaag tagtcctgtg aatgccactg   2520

ccttcgcttc ttgcctctgt gctgtgtgtg acgtgaccgg acttttctgc aaacaccaac   2580

atgttgggaa acttggctcg aatctctgtg ccttcgtctt tcccatgggg agggattctg   2640

gttccagggt ccctctgtgt atttgctttt ttgttttggc tgaaattctc ctggaggtcg   2700

gtaggttcag ccaaggtttt ataaggctga tgtcaatttc tgtgttgcca agctccaagc   2760

cccatcttct aaatggcaaa ggaaggtgga tggccccagc acagcttgac ctgaggctgt   2820

ggtcacagcg gaggtgtgga gccgaggcct accccgcaga caccttggac atcctcctcc   2880

cacccggctg cagaggccag aggcccccag cccagggctc ctgcacttac ttgcttattt   2940

gacaacgttt cagcgactcc gttggccact ccgagaggtg ggccagtctg tggatcagag   3000

atgcaccacc aagccaaggg aacctgtgtc cggtattcga tactgcgact ttctgcctgg   3060

agtgtatgac tgcacatgac tcgggggtgg ggaaaggggt cggctgacca tgctcatctg   3120

ctggtccgtg ggacggtgcc caagccagag gctgggttca tttgtgtaac gacaataaac   3180

ggtacttgtc atttcgggca aaaaaaaaaa aaaaaaa                            3217


<210>  866
<211>  2517
<212>  DNA
<213>  Human

<400>  866
aggcaagtgt caggccgatg tgtcgcccgc gaggggccgg ggtcggggcc gccggggcca     60

tgcgcgcggg ctgggcaggg ggccggcggg gcgcagagcg gagccgcctc ggagcctgag    120

ccgcccgggg ccggggccgg ggagccgcgc ggggccggcc ggccgggggg aggggagcga    180

tgcggcgccg gcgggcggca gtggccgcgg gtttctgcgc ctccttcctg ctgggctccg    240

tcctcaacgt gctcttcgct ccgggctcgg agcctccgag gccaggccag tcccctgagc    300

cttcgccggc cccgggtccg ggccgtcgcg ggggccgcgg ggagctggcc cggcagatcc    360

gggcgcgcta cgaggaggtg cagcgctatt cccgcggggg ccccgggccc ggggcgggcc    420

ggccggagcg gcggcgcctg atggacctgg ctccgggcgg gcccggcctg ccgcgccccc    480

ggcccccttg ggcccggccc ctgtccgacg gcgccccagg ctggcccccg gctcccggcc    540

caggctcccc cggcccgggc ccgcgcctgg gctgcgccgc gcttcgcaac gtgtccggcg    600

cgcagtacat gggctcaggc tacaccaagg ccgtgtaccg ggtccgcctg cccggcggtg    660

ccgcggtggc gctcaaggcg gtggacttta gcggccacga tctgggcagc tgcgtgcgcg    720

agttcggggt acggaggggc tgctatcggc tggcggccca caagctgctt aaggagatgg    780

tgctgctgga gcggctgcgg caccccaacg tgctgcagct ctatggctac tgctaccagg    840

acagcgagga catcccagac accctgacca ccatcacgga gctgggcgcc cctgtagaaa    900

tgatccagct gctgcaaact tcctgggagg atcgattccg aatctgcctg agcctgggcc    960

gcctcctcca ccacctggcc cactccccac tgggctccgt cactctgctg gacttccgcc   1020

ctcggcagtt tgtgctggtg gatggggagc tcaaagtgac ggacctggat gacgcacgtg   1080

tggaggagac gccgtgtgca ggcagcaccg actgcatact cgagtttccg gccaggaact   1140

tcaccctgcc ctgctcagcc cagggctggt gcgagggcat gaacgagaag cggaacctct   1200

ataatgccta caggtttttc ttcacatacc tcctgcctca cagtgccccg ccttcactgc   1260

gtcctctgct ggacagcatc gtcaacgcca caggagagct cgcctggggg gtggacgaga   1320

ccctggccca gctggagaag gtgctgcacc tgtaccggag cgggcagtat ctgcagaact   1380

ccacggcaag cagcagtacc gagtaccagt gtatcccaga cagcaccatc ccccaggaag   1440

actaccgctg ctggccatcc taccaccacg ggagctgcct cctttcagtg ttcaacctgg   1500

ctgaggctgt ggatgtctgt gagagccatg cccagtgtcg ggcctttgtg gtcaccaacc   1560

agaccacctg gacaggtcgg cagctggtct ttttcaagac tggatggagc caagtggtcc   1620

ctgatcccaa caagaccaca tatgtgaagg cctctggctg acctatctga gggctcggct   1680

gaccagctga ctatcctcag cagctgggct tgcctgtgga gggagtgact tgcactggca   1740

gcactgcatg tcacctggga acccctgcag acaaagctaa catcccagac agacagatgt   1800

gaccaggaca aacgtgcaat aatgccaaat gttaaaatgt gagtttacca gcctagctat   1860

gggactgctg gctcctagtc caggaatcat gggggtatga ctgcctctcc aaccctgtgg   1920

gctgtaagca agctcaggct agtctcccca ctgggggctg tgcccctccc tgggacggtt   1980

ccgtgggcag ccccatcact gtgttcaata gtgtgagaat gtagctaaag cccctgctgc   2040

tgctgctgca catgccacag caggcggtgg gggctgcgtg gggacaatcc atcgtggagt   2100

gttctctcag cttaggtctg gacaggagac ttggcgggag atgctccagg atgtgggtga   2160

ttctgtacct ggggaggcta tctctgacct cccgacaggg gacactccca ggccagccca   2220

ggggtcaggg gcagaggtgc acacctcagc atgagccaag actggggtca gggagcaggt   2280

gtggtttgag ccaggacctg gggcgggggt ggggccgggg cctttctgcc tcatttgctt   2340

tcaatgaaag cctcaaagca gccaaaacca ggctttcccc cttcctcgag tttgaatatc   2400

cagaatcttt tgtacttctt gttggttaaa ttgtttattt ttgtaaaaaa taaaataaaa   2460

ttagttaata aaatgatgtt tcacagcaaa ctcttcccta aaaaaaaaaa aaaaaaa      2517


<210>  867
<211>  2358
<212>  DNA
<213>  Human

<400>  867
gcagaaggga agcaactccg ggcgcctttc ttttgcgcag gcgtcgcgcc ctggggccgg     60

ggccgggcgg caccgcggtg cgcaagcgca accgtcggtg ggtcggggat cggtcgcctg    120

agaggtatca cctcttctgg gctcaagatg gacaacaaga agcgcctggc ctacgccatc    180

atccagttcc tgcatgacca gctccggcac gggggcctct cgtccgatgc tcaggagagc    240

ttggaagtcg ccatccagtg cctggagact gcgtttgggg tgacggtaga agacagtgac    300

cttgcgctcc ctcagactct gccggagata tttgaagcgg ctgccacggg caaggagatg    360

ccgcaggacc tgaggagccc cgcgcgaacc ccgccttccg aggaggactc agcagaggca    420

gagcgcctca aaaccgaagg aaacgagcag atgaaagtgg aaaactttga agctgccgtg    480

catttctacg gaaaagccat cgagctcaac ccagccaacg ccgtctattt ctgcaacaga    540

gccgcagcct acagcaaact cggcaactac gcaggcgcgg tgcaggactg tgagcgggcc    600

atctgcattg acccggccta cagcaaggcc tacggcagga tgggcctggc gctctccagc    660

ctcaacaagc acgtggaggc cgtggcttac tacaagaagg ctctggagct ggaccccgac    720

aacgagacat acaagtccaa cctcaagata gcggagctga agctgcggga ggcccccagc    780

cccacgggag gcgtgggcag cttcgacatc gccggcctgc tgaacaaccc tggcttcatg    840

agcatggctt cgaacctaat gaacaatccc cagattcagc agctcatgtc cggcatgatt    900

tcgggtggca acaacccctt gggaactccc ggcaccagcc cctcgcagaa cgacctggcc    960

agcctcatcc aggcgggcca gcagtttgcc cagcagatgc agcagcagaa cccagagttg   1020

atagagcagc tcaggagcca gatccggagt cggacgccca gcgccagcaa cgacgaccag   1080

caggagtgac gctgcctgct cccggtgtga ccgcgtcctt ccctggccga cccgaaggaa   1140

gccttctggt tgtctgccac ttcctcctgt tggactgcct gagagagggg aagagagaga   1200

cctcggacct gcatgtcaag atggattttc cccttttatc tctgccctcc tccactccct   1260

ttttgtaact cccttacagc ccccagaccc ttcttgaaac gagagccagc aagctgagca   1320

cagaccagca gcgacctccc ttccagcccc cagaaagctc ggtcacttga gtgttttcta   1380

gaatcctggg gtgctcccgg gccgctctca gagaagtggc aggtttcacg ttcagccgtg   1440

tggcggatcg tgtggcttcc aaagcctttt acagcccccg ccccccatcc cgtggtctgt   1500

ctgcaggaac tctcccgtct gtgagaagcc tctttccgag tcgacctccc ggccaccccg   1560

gccctgtgcc tgctcggaag agctcactgc cagctgcggc ctgggcaccg cgggccatgt   1620

gtgtttgcat gaggaactct ttagtggcag acacctaaga gacggctgcg gtcaccccac   1680

gcctccgcgg ctcaggagcc gtcctgggtg cataggacca gtttctgtga cttttctcca   1740

gttgggcatg ttgacagaca tgtttcccct cctcccaccc tcattttctg gtcctcgcga   1800

ctgagagcca ggggcgacat catgaccttc tgtcccggcc gccttagccc cgggcacagg   1860

gaaggcagct gggccgtttc tgtctgtgtc ccatcctgct gtccttctgt cctggatgtt   1920

tcatgggccc ggggcccccc agggaagctt acccctcctg tgctgggtgg aggccacggg   1980

acacctcagg tgccacccac cttggcccta aaacagccac caggaaagca gccggagagc   2040

cggacagcag gcagcctgtc tgggttcctg aggcctgggg gtggcagacg agcccacggc   2100

gccgtggtcc cagcagcagg gttgtcagtc ggagcatcct ggggctccct ggctcctggc   2160

cgtctgtgag gtaggcgcag taccgtgtat cgtaggtagc agtaggaacg ggggccgccg   2220

cggccctgca gccgctcatg gcggtgaggt gtgtgccaag cccacccggg gtgcagggcg   2280

tgacgtgtgg ggaataaata ggcgttgtga cctctaaaaa aaaaaaaaaa aaaaaaaaaa   2340

aaaaaaaaaa aaaaaaaa                                                 2358


<210>  868
<211>  3569
<212>  DNA
<213>  Human

<400>  868
cgcccgcggc cgggccgcat tgtgacgtag cggggccgcg gcagcgcctc caccgcccgc     60

ctacttcggc tgaggctgtt ctgctcctgc cgctgcggtc cgtcggtcgg tcagtcagtc    120

ccttcgcgct cctgagccgc cggcgcgccg ggcgccccgg gaatttataa gtatttgacc    180

gtactcaaaa tgtgcaagga agaataatgg aagcccctga ataccttgat ttggatgaaa    240

ttgactttag tgatgacata tcttattcag tcacatcact caagacgatc ccagaactgt    300

gccgaagatg tgatacgcaa aacgaagaca gatcagtttc tagctctagc tggaattgtg    360

gcatctcaac tcttattaca aacacgcaaa agcccacagg aatcgctgat gtgtacagta    420

agttccgccc agtgaagcgg gtttcgccac tgaaacatca gccagagact ctggagaaca    480

atgaaagtga tgaccaaaag aaccagaaag tggttgagta ccagaaaggg ggtgagtctg    540

acctgggccc ccagcctcag gagcttggcc ctggagatgg agtgggcggc ccaccaggta    600

agagctctga gcccagcaca tcgctgggtg aactggagca ctacgacctc gacatggatg    660

agattctgga tgtgccttat attaaatcca gtcagcagct tgcctctttt accaaggtga    720

cttcagaaaa aagaattttg ggcttatgca caaccatcaa tggcctttct ggcaaagcct    780

gctctacagg aagttctgag agctcatcat ccaacatggc accattttgt gttctttctc    840

ccgtgaaaag ccctcacttg agaaaagcat cagctgtcat ccacgaccag cacaagctgt    900

ccactgaaga aaccgagatc tcacctcctc tggttaaatg tggctctgca tatgagcctg    960

aaaaccagag taaagacttc ctaaacaaga catttagtga tcctcatggt cgaaaagttg   1020

agaagacaac accagactgc cagctcaggg ccttccacct acaatcctca gcagcagaat   1080

ccaaaccaga agagcaggtc agtggcctaa accggaccag ctcccaaggc ccagaagaaa   1140

ggagtgagta tctgaaaaaa gtgaaaagca tcttgaacat tgttaaagaa ggacagatct   1200

ctctcctgcc acacctagct gcagacaatc tagacaaaat tcacgacgaa aatggaaaca   1260

atctattaca tattgcggcg tcacagggac acgcagagtg tctacagcac ctcacttctt   1320

tgatgggaga agactgcctc aatgagcgca acactgagaa gttgactcca gcaggcctgg   1380

ccattaagaa tggtcagttg gagtgcgtac gctggatggt gagcgaaaca gaagccattg   1440

cagaactgag ttgttctaag gattttccaa gccttattca ttacgcaggt tgctatggcc   1500

aggaaaagat tcttctgtgg cttcttcagt ttatgcaaga acagggcatc tcgttggatg   1560

aagtagacca ggatggcaac agtgccgttc acgtagcctc acagcatggc taccttggat   1620

gcatacagac cttggttgaa tatggagcaa atgtcaccat gcagaaccac gctggggaaa   1680

agccctccca gagcgccgag cggcaggggc acaccctgtg ctccaggtac ctggtggtgg   1740

tggagacctg catgtcgctg gcctctcaag tggtgaagtt aaccaagcag ctaaaggaac   1800

aaacagtaga acgtgtcacg ctgcagaacc aactccaaca atttctagaa gcccagaaat   1860

cagagggcaa gtcactccct tcttcaccca gttcaccatc ctcacctgcc tccagaaagt   1920

cccagtggaa atctccagat gcagatgatg attctgtagc caaaagcaag ccaggagtcc   1980

aagaggggat tcaggttctt ggaagcctgt cagcctccag ccgggctaga cccaaagcaa   2040

aagatgaaga ttctgataaa atcttacgcc agttattggg aaaggaaatc tcagaaaatg   2100

tctgcaccca ggaaaaactg tccttggaat tccaggatgc tcaggcttcc tctagaaatt   2160

ctaaaaagat cccactggag aagagggaac tgaagttagc caggctgaga cagctgatgc   2220

agaggtcact gagtgagtct gacacagact ccaacaactc tgaggacccc aagactaccc   2280

cagtgaggaa ggctgaccga ccaaggccgc agcccattgt agaaagcgta gagagtatgg   2340

acagcgcaga aagcctgcac ctgatgatta agaaacacac cttggcatca gggggacgca   2400

ggtttccttt cagcatcaag gcctccaaat ccctggatgg ccacagccca tctcccacct   2460

cagagagcag cgaaccagac ttagaatccc agtatccagg ctcagggagt attcctccaa   2520

accagccctc tggtgaccct cagcagccca gccctgacag tactgctgcc cagaaagttg   2580

ccacaagtcc caagagtgcc ctcaagtctc catcttccaa gcgtaggaca tctcagaact   2640

taaaactgag agttaccttt gaggagcctg tggtgcagat ggagcagcct agccttgaac   2700

tgaatggaga aaaagacaaa gataagggca ggactctcca gcggacctcc acaagtaacg   2760

aatcggggga tcaactgaaa aggccttttg gagcctttcg atctatcatg gagacactaa   2820

gtggcaacca aaacaataat aataactacc aggcagccaa ccagctgaaa acctctacat   2880

tgcccttgac ctcacttggg aggaagacag atgccaaggg aaaccctgcc agctccgcta   2940

gcaaaggaaa gaataaggca gcataatgac atcaatagaa aaatgaagaa atcctacagc   3000

ataaagcaca ttgctgagcc agagtcaaaa gaactcttct tgtaaatcac tttttaaatt   3060

ttctctcact gatgcccttt ggaaattatt ggaaatttct ggactatcct ctttggaaag   3120

agaaccatga aaacaatgcc tcaccagcag aagaacagaa tatcaggatg ccttaaattt   3180

atagtagtag actgtaaaag attcattttg gggtgatatc tgtatatata acttgttttt   3240

ttaaaagatg ccgtttaaaa gcatgattgg gaaaatgtat gttttttaag agtagattga   3300

ttcaccctac ccacaggaca ttcaccaagc cactgatacc attttatatt tcatcaattg   3360

catgagtatt tgctaatgtt gattgaacct ccctttcccc ataatgtggg cagatttggc   3420

tcagctcctt catgagatca ggtcagtggt attgtttctg tcaagagtgt tttttctgtc   3480

atttctactt tttgtataaa ggaaataaaa caatgttaac agccacctat aagcttgggg   3540

cacctacttt ctaacaaatc tgtgatgtt                                     3569


<210>  869
<211>  1038
<212>  DNA
<213>  Human

<400>  869
aagacgcacc gccccctctc agtcactccc aagatggcgg acctactggg ctccatcctg     60

agctccatgg agaagccacc cagcctcggt gaccaggaga ctcggcgcaa ggcccgagaa    120

caggccgccc gcctgaagaa actacaagag caagagaaac aacagaaagt ggagtttcgt    180

aaaaggatgg agaaggaggt gtcagatttc attcaagaca gtgggcagat caagaaaaag    240

tttcagccaa tgaacaagat cgagaggagc atactacatg atgtggtgga agtggctggc    300

ctgacatcct tctcctttgg ggaagatgat gactgtcgct atgtcatgat cttcaaaaag    360

gagtttgcac cctcagatga agagctagac tcttaccgtc gtggagagga atgggacccc    420

cagaaggctg aggagaagcg gaagctgaag gagctggccc agaggcaaga ggaggaggca    480

gcccagcagg ggcctgtggt ggtgagccct gccagcgact acaaggacaa gtacagccac    540

ctcatcggca agggagcagc caaagacgca gcccacatgc tacaggccaa taagacctac    600

ggctgtgtgc ccgtggccaa taagagggac acacgctcca ttgaagaggc tatgaatgag    660

atcagagcca agaagcgtct gcggcagagt ggggaagagt tgccgccaac ctcctaggcg    720

ccccgcccag ctccctttga cccctggggc agggcagggg gcagggagag acaaggctgc    780

tgctattaga gcccatcctg gagccccacc tctgaaccac ctcctaccag ctgtccctca    840

ggctggggga aaacaggtgt ttgatttgtc accgttggag cttggatatg tgcgtggcat    900

gtgtgtgtgt gtgtgagagt gtgaatgcac aggtgggtat ttaatctgta ttattccccg    960

ttcttggaat tttcttcccc atggggctgg ggtactttac attcaataaa tactgtttaa   1020

cccaaaaaaa aaaaaaaa                                                 1038


<210>  870
<211>  8475
<212>  DNA
<213>  Human

<400>  870
gttgtgacca ctgaacaaaa cttgcccatt gaaagcaaac ccggaacagc tggataatgt     60

ccaccccgag ccgattcaag aaggacaaag agatcatagc cgagtatgaa agtcaagtca    120

aagaaattcg agctcaactg gtagaacaac aaaaatgcct ggagcagcaa acggagatgc    180

gagttcagct tctccaggat ctgcaagatt tcttccgaaa aaaagctgaa attgagacgg    240

aatattcccg gaatctagag aagttagcag aaaggttcat ggcaaaaaca agaagcacta    300

aggatcatca acaatacaag aaagaccaga acctgttgtc tccagtgaac tgctggtatt    360

tgctcctgaa ccaagtaagg agagaaagca aagaccatgc aaccttgagt gacatctatc    420

tgaacaatgt gattatgcgg ttcatgcaga taagtgagga ttctaccagg atgtttaaaa    480

agagcaaaga gattgcattc caacttcatg aggatttaat gaaggttctt aatgagcttt    540

atacggtgat gaaaacatac catatgtatc atgcagagag catcagtgca gagagcaagc    600

tgaaagaggc cgaaaaacaa gaggaaaagc aaattgggag atctggtgat ccagtcttcc    660

atattcgact agaggagaga catcaacggc gaagctctgt aaagaaaatt gaaaaaatga    720

aagaaaaaag acaagcaaaa tattcagaaa ataagctaaa atcaattaag gcacggaacg    780

aatatctcct aacacttgaa gccaccaatg cctcagtttt caagtactat attcatgatc    840

tttctgattt aattgattgc tgtgatcttg gctaccatgc aagtctgaac agagccctaa    900

gaacatatct gtctgcggag tacaaccttg aaacctccag acatgagggc ttagacatta    960

ttgagaatgc agttgataat ttagagccca ggagcgataa gcagagattc atggagatgt   1020

accctgctgc gttctgtcca ccaatgaagt ttgagtttca gtctcacatg ggtgatgagg   1080

tgtgccaggt cagtgcccag cagccagtcc aggcagagct catgctcagg taccaacagt   1140

tgcagtcccg ccttgccacg ctcaaaatcg agaatgaaga ggttaagaaa acgactgaag   1200

ccaccttgca gacgatacaa gatatggtca ccatcgagga ctatgatgtt tctgaatgct   1260

tccagcacag tcgttccaca gaatcagtga agtccactgt ctctgaaacc tacctgagta   1320

aacccagcat cgccaagaga agagccaacc agcaggaaac tgaacagttc tacttcatga   1380

aactcagaga atatttggaa ggcagtaatc tcatcacaaa acttcaagcc aaacatgact   1440

tgctgcagag gaccctggga gaaggtcata gagctgaata tatgactaca aggcctccaa   1500

atgttccccc taagccccag aaacacagga agtccaggcc ccgctcacag tataatacta   1560

agttgtttaa tggggatttg gaaacattcg tcaaggactc aggacaggtt attcccctca   1620

ttgtggaaag ctgtattcgg ttcatcaatc tctatggtct tcagcatcag gggattttca   1680

gagtgtctgg ttcccaggtg gaagtcaatg atattaaaaa ttcatttgag agaggtgaaa   1740

atcctttggc tgatgaccag agtaaccatg atattaactc agttgctggc gttctgaagc   1800

tctatttccg tgggctggaa aaccccctct ttcctaagga aagatttaac gatctgattt   1860

cttgtatcag aatagataat ctctatgaga gggcgcttca catccgcaaa ctcctcctga   1920

ctttgcccag gtcggtcctt atagtgatga ggtacctctt tgccttcctc aatcatctat   1980

cacagtacag cgatgagaat atgatggacc cttataacct ggccatttgc tttggcccaa   2040

cattgatgcc tgtcccagaa atacaggatc aagtgtcttg ccaggcacat gtgaatgaaa   2100

ttatcaaaac catcatcatc caccatgaga ctattttccc agatgctaaa gagctggatg   2160

gccctgttta tgagaaatgt atggctggag atgactattg cgacagccca tacagtgagc   2220

acggtacatt ggaggaagtg gaccaagatg ctggtacaga gccccacaca agtgaagatg   2280

aatgtgagcc aatagaagca atagccaagt ttgactatgt tgggcggtct gccagagaac   2340

tatccttcaa gaagggtgcc tccctgctgc tgtatcaccg tgcatctgag gactggtggg   2400

aaggcaggca caacgggatt gacgggctgg tgcctcacca gtatatagtg gtgcaggata   2460

tggatgatac gttttcagac actctgagcc aaaaagccga cagtgaggcc agcagtgggc   2520

cagtcacgga agacaagtcc tcatccaagg acatgaactc cccgacagac cgtcatcctg   2580

acggctattt agccaggcaa cgaaaaagag gagagccacc ccctccagta aggcgtcctg   2640

gcaggaccag tgatggccat tgcccgctcc accctccaca tgccctttct aactcctcag   2700

ttgacctagg gtccccaagc cttgccagtc acccccgggg cctgctgcag aaccgtggcc   2760

tcaacaatga cagtcctgag cggaggcgca ggcctggcca tggcagcctg accaacatca   2820

gccggcacga ctccctcaag aagatcgaca gccctcccat tagaaggtcc acgtcatcag   2880

ggcaatacac gggcttcaat gaccacaagc cactggaccc agagacaatt gctcaggata   2940

ttgaagaaac gatgaacaca gctttgaatg aactccgaga actggagaga cagagcacag   3000

caaagcatgc ccctgatgtg gtgctggata ccctggagca agtgaaaaac tctcccaccc   3060

ctgccacttc cacggaatct ctcagccctt tgcacaacgt tgccctcagg agctccgagc   3120

ctcagattcg acgtagcacg agctcctcca gtgacacaat gagtactttc aagcctatgg   3180

tggcacccag aatgggcgtg cagctgaagc ctccagccct taggccaaaa cctgctgttc   3240

ttccaaaaac aaatcctacc ataggacctg ccccacctcc ccagggtcca acagacaagt   3300

catgcacaat gtaaaaacca gccaagcaag gccataaagg gaggtgactt aaaaaagaaa   3360

atggattagt gacaaaagtc actgatccat aactttcctt agttttgtgc ttataactgg   3420

agatcttttg gcttttctat gttgtcgaat gtaatgtctg agactagcta aattaacacg   3480

ggcatttgta ttttgtaatt tttttaaata actggacata tgtcatttta aggacaatag   3540

aaacacttag acttacttga aaatccaatg ctgcaccact tgtaatgaag gcaacaccgc   3600

tctccacatt gtacagagct tcaggtttaa tgtagcccag ctgagtcaga aaggttgtga   3660

cctgaaggca gaagaacccg aatgccacac ctcattggag tatagccagt gttggtctgt   3720

ggcacttggg ctgaaaggtg ataatggcat tgcgtggtag ctgacaatga gcaccttcgg   3780

ttccatgtgg agcggggttt agctcatgca aaagacttgc aattgtctcc atgggacgat   3840

cccagtggga ctgtcagccc acagctcgag tgggttggat gcttgcctct ttcctaacag   3900

ttatttcccc gggtccagct taaagactcg atggaaggag gtagaacctc tgctgttact   3960

gcttgaactt aacctgggaa aggagaggaa gacaccatct ccaaagctat taatgtcact   4020

ccttttgcga gcatgattag gccccggaga tttccaagtc cccccatcta cacttacaaa   4080

cgattagaag ggtttaattt taaagacttt ctggttacac tactccacga actcctccaa   4140

agatccgtta ttcaataact gcctagaaaa tgtttccatc tcctctaaat ccctgtgttc   4200

tcctctgtgg aaatgaaggc agcaagaagc acctgaggcc ttggttcatg cagtgttctc   4260

ttttgactaa atcacctagg ttcctttaaa catgctacaa agcccaggca tggtggtgca   4320

cacctgtact cccagctact cgggtggttt acacaggagg atggctttgg gcctagtagt   4380

tcgagtccag cctgggcagc atagtgtgag accctgtctc ttaaaaaaaa aaaaaatgct   4440

acaaagtcct gatgatccta aatttgaaat cccaactgtc ctctccattt gtctttgagc   4500

caaccctgaa ctggccctgg tacctgagta agagccatgc agggccatca gcagaacatg   4560

gccttgtggt tctcacccag ttgtgtacct cacaaccaca acttcttttt ctttgtccct   4620

tttccccttt ttggttttgg ttttgtatgt gggctctatg taactcccat agtcagctga   4680

actctcaatt ggagaccctc tttctctggc atcctagcac acaggcaatt ttttaagcct   4740

atatttatgc tacattttcc cccatcttaa gaaaatttgc tttgatttcc attctcctac   4800

tagcagcagc tgatatcacc tgtagaccta tgagcatttt atctattcta tcattgaagt   4860

tactgataaa gatttttgtt gttgttgttg ttgttgggag aaatggattt cccacaacta   4920

atccctctgg cccaccatta atttccttct tggtttcatt tcaaactggc agccaattgc   4980

acgcccatct aagagctaca cagtgtagat tttacttcat cagcccattg gtgaatgcat   5040

cgtgcagaaa agaactggga tctgtactaa aatcaagatc attactttga tctctacctc   5100

agtttgccag tgtagtcatt ctattgcagg aagagattaa attgatgaga tattgttact   5160

ttcagagtca cactgctgat tgcttgcctg gggcctaatt tcacaaatga atagtgactt   5220

ttttcccatg tatttctagg tatggtaaac ttttaaacct ccaaattttc agagccatac   5280

tttttgccca ttttgaaaaa gaagcccagg acagcacctt gtctagcccc tccccatttc   5340

tcctgagctt ttggggtcct tcagcaccct tggacaccgt ggagatccag ccaagactga   5400

gctttgaata gcactagccc ttttaaacaa tcctcacaaa ttccttagga atttaaactt   5460

tccaaaataa tcccccactt tttttttttt tttttttttt ttttgagttg gagtcttgct   5520

ctgtcgccca ggccagagta cagtggtgca atctcggctc cctgcaacct ccatctcccg   5580

ggttcaagca attctcctga gtagctggga ttacaggcgc caccaccacg cccagctaat   5640

ttttgtattt ttagtagaga tggggtgtca ccatgttggc caggctggtc tcaaactcct   5700

gacctcaggt gacccaccag cctcagcctc ccaaagtgct gggattacag atgtgagcca   5760

ccatgcccgg ccattccacc acttctttaa aatagtaaga attcttaaaa accatattcc   5820

ttgtttgatg gaagagtaag atgttaacag agggcatcaa agggccagag gtgtctttga   5880

atttattttt tttcaatgtc ttttctgagc ttcagcctta gcttttcaga tcttcctcct   5940

acctgttcat ttattcagcc ttctatctgg tcatcctccc cagcggctcc tctctctgat   6000

gtgtccacct acggtggaac gaggattgcc tttctgtgct ccccatcagg actttgctgt   6060

cttggccggc aggagtcgtg ctgctgcaga gcctcacagg ctgtgccttg tttcaggaaa   6120

cagctcctaa tactctccca tcactcactt tacctgtctc catcttattt ccctatactc   6180

ctattgtcag cttgagactt tttttttttt tcaattccaa atgaagggta tgacctcaga   6240

gtgagtgagg actcagtaaa gactcacctc tccttacttg gtttattaaa tgtcttcaga   6300

ttccagagat aagacaaggt ggccacttca caaagaatcc agaatcatgc tcagtaaagc   6360

tcattaaaag ccactgcagc tgagaaggtt cacagccctt ctttatagcc acagaggcag   6420

cacacagggg aggtgggaag acacagggaa acgagagaag aaggataatg aggccttgag   6480

gtgttctgcc cccaatttca aggagcttat caggcttcat gtgcaatttg gggaggggag   6540

ctttttgatg gtgggtaaat aatggctcta caaagattac ctgactccac tgacacaaga   6600

atatgtattc tcagctgata taactgtgtg ttcacatccc atccatagaa ctcactgaag   6660

gagattcatc aagtcagcct tttggactgg gttggggttt ggggagtgga tttggggata   6720

gagagaaagg tgtacttagt acacattttc taatgggcgt tacgtgaact gtttgaacct   6780

gctgagtggc gctttgtaga gctccatgtt cacgttcagt gtcaacacca ttcaacagct   6840

ttgcacatct tcgtacaaca taatctggct ttggtgcccc ttgagccacc tgtagaataa   6900

tttatagcag ggtcccacaa tctactgcaa tgatcgtgaa cagttatcag tggatatagt   6960

gctccaagag tcaaattgta tccgttaagg gttttctaac ttttgctatc ccccccgcga   7020

ccaaaaaaag ggggggttta taatttaaag aaaaggaaaa gaggcgtggg ttggtagttg   7080

tgtccttaac atttaggaat gacatagcct ctggagtcta caaactgaag aaactttcat   7140

ctgatcagcc ttggaaatcc aaagttaaag agcctatgtg tctcttgagg cgggggttag   7200

aggattcaaa tttgggatga tgctcattga ttcctgacca tagcagtgag aggccatttt   7260

ttgtgcagga aatgtgctta ggactcagtc ttgttttcga ttatccacca cagaaaccct   7320

gagacacaga gcagcttaga agtctctacc caggcgtaaa tagagctccc tactccagac   7380

cacctgccac ccacctccca agttgagaac acaagctcca gctgggctgg agagtcaggc   7440

ttggtgcagg gtgactttgg cgaagttttg tcagatccat aaagcaaact ggaatttgag   7500

ctttcactta ccctagtata cgttcttaaa aaaaaaaaaa agtctatgtg gtataatcga   7560

gatggatacc tgtgtcttta aattacgtag ggaattttgt atgtttaaat aattgtactg   7620

ggttccataa tgcttatctt agaaacttta gtaaaagaaa atatatgaac cgtgcatttg   7680

tgaatgcccc ccttagagca ttcatccaag ttcagtgtgt agtgtgatgg ttattataga   7740

tatttaaagt atagtaagtg gctgtgtaac aggagagact gctgtttacc tacgtactga   7800

agggtaactg ctgcccgcgt aattaaatca gtattgtcct ttcctgtcgg tttgatcaat   7860

tgcggtaccg gtagcttcct gcttgtgact gttacctaat tgtgtcaatg tacatctgta   7920

gtatgtacat gtgaaagtgc ctttctattt tagaggagtt ttagccttgc tcttgtaccg   7980

ttgccccgct ctgtgcccca cccccacctc ctcctcccaa ttcctgctgc ccactcgagt   8040

gtttcgaagc ttcctccctg tcccccacct tccccatccc cgccttcctg tgcctcggtg   8100

ctcagtaatg tcccatctca cctccctgtc ggtcctcaga ctgtctcgtt ttccttgtag   8160

acgtgattgt gcctttctca cccctgtgtc ctcccatccc accgcatcag tcccccgctc   8220

atgtgctgct gacagcatcg cattcgcccg tgctctgtac tgcctctcac catttcattc   8280

cctcctctct gaggtgaaaa taaaggggga tgcttttaca gtctggaaag aaaaaaaatg   8340

ttttgttaat ctgttgtgac aatgcacttt tatgtatagt actgtacatt tttggcatgt   8400

accattacag gcttcagtat acagtcaggt ttgttcttca cggtgtatct ttataataaa   8460

taagatagtt ctggc                                                    8475


<210>  871
<211>  5308
<212>  DNA
<213>  Human

<400>  871
ggcctgctcc gggcgcgtca ggcagggggt ggggagcagg ggccgggcgg gcgctcggct     60

cccagccgcg ctccctcggg ccactagcgc tcccgcgcgc gcccggccgc cttcatgtga    120

agcgccggcc ctccgcccct tccctcccct tccttccctc cctccctccc tgtcccctcc    180

tcctcctcct cctcctccgg cgcccgcttc agctccccgg ggccccctgc ccggccgggc    240

gctgacagca agggcggggg tccctgccgc cgccttgtct cgcgcagggt ccggctgggg    300

tagcggagcc cccagtgcgg ccatggaccg gcccctgtcg tcgtcggcgg aggcggagga    360

ggaactggag tggcaagtgg cgagtcgcag gaggaaggcc tgggccaagt gccgcagctc    420

ctggcaagcg tcggagacgg aggatctgtc cacagaagcg acgacgcagg acgaggagga    480

ggacgaggag gaggacctcc ccggcgcgca gctgccggca gcggggggaa gaggaaacgt    540

gcccaacgag aagatcgcga tatggctcaa ggactgccgt acacctttgg gagcctcact    600

ggatgaacaa agcagtagta cactcaaggg tgtgcttgtg agaaatggag gaagttttga    660

agatgatttg tcattgggag ctgaagccaa ccacctccat gaaagtgatg ctcaaattga    720

aaactgcaat aatatcttgg ccaaagagag aagattacag tttcatcaga aagggagaag    780

tatgaattcc actggatctg ggaaaagtag tgggacagtt tcaagtgttt cagaattgtt    840

ggaactttat gaggaagatc ctgaagaaat tctttataat cttggatttg gacgtgatga    900

accagatatt gcttctaaaa ttccttccag attttttaat tcatcatcct ttgccaaagg    960

gatagatatt aaagtatttt tgagtgctca gatgcaacgg atggaagtag aaaacccaaa   1020

ttatgcttta acaagccgtt ttcgtcaaat tgaagtgctt actactgtgg ccaatgcgtt   1080

ttcttcttta tattctcaag tctccgggac gcccctgcag agaattggaa gtatgtcctc   1140

agtgacctct aacaaggaga cagacccacc tccaccttta actcgaagta acactgcaaa   1200

tcgtttaatg aaaacactct caaaactgaa tttatgtgtt gataaaacag agaaaggaga   1260

aagtagtagt ccttctccat cagctgaaaa aggaaagatt ctaaatgttt cagtgattga   1320

agaaagtggc aataaaaacg atcaaaagtc tcaaaaaatt atgaagaaga aagagtcatc   1380

ttctatgttg gctacagtta aagaagaagt ctctggtagt tcagcagctg ttacggagaa   1440

tgctgatagt gatagaattt ctgatgaagc aaatagtaat tttaaccaag gaactgaaaa   1500

tgaacaaagt aaagaaactc aaagtcatga gagtaaactg ggtgaggaat ctggtattgt   1560

agaatccaaa ttagatagtg atttcaacat atccagccac agtgagctgg aaaatagcag   1620

tgagctgaaa agtgtccata tatccacacc tgaaaaagag ccttgtgcac cactgacaat   1680

accatccata agaaatataa tgacacagca gaaggactcc ttcgaaatgg aagaggttca   1740

aagtacggag ggagaagctc ctcatgttcc agccacttac cagctaggtc ttacgaagtc   1800

gaaaagagat catctgttac gtactgcaag tcagcattcc gatagcagtg gttttgctga   1860

agattctaca gactgcctat cccttaatca tcttcaggtt caggagtcct tgcaggctat   1920

ggggagtagt gctgatagtt gtgacagtga gacaacagtt acgtcacttg gtgaagacct   1980

tgccacacca acagcacaag accagcctta ttttaatgaa tcagaggagg agtctcttgt   2040

ccctcttcag aagggactag agaaggcagc agcagttgca gacaaaagaa aatcaggtag   2100

ccaggatttc cctcagtgca acaccattga gaatacagga actaaacagt ccacctgtag   2160

tccaggggat catatcattg aaattactga agtggaagag gatttgtttc cagcagagac   2220

agtagagcta ctgagggaag caagtgctga aagtgatgtg ggtaaaagca gtgaaagtga   2280

atttactcag tataccacac accatattct gaaatcattg gcttctattg aagctaaatg   2340

cagtgatatg agctctgaaa atacaactgg gcctccctct tccatggaca gagttaatac   2400

agctttgcaa agagctcaaa tgaaggtttg cagtctgtct aatcaaagga tggggcgtag   2460

cctgctaaaa tcaaaagatt tgttaaaaca aaggtactta tttgcaaaag ctggctatcc   2520

tctaagaagg tctcagtctt taccaaccac cttattgagc ccagtaaggg ttgtgtcctc   2580

tgtcaatgtt cgattatctc caggaaaaga gaccagatgc agcccacctt ccttcaccta   2640

taagtacaca cctgaagagg agcaggaatt ggaaaagcgg gtgatggaac atgatggtca   2700

gtctttagtt aaatcgacca ttttcatctc tccatcatct gtgaagaaag aagaagcccc   2760

ccagagtgag gcgccgcggg tggaggaatg ccatcatgga aggactccta cctgttcacg   2820

gcttgctcca ccaccaatgt ctcagtctac ctgttccctt cattccatcc actctgagtg   2880

gcaagaaagg cccctgtgtg agcacacaag aactctgagc actcacagtg ttcccaacat   2940

atcaggggct acttgtagtg ccttcgcttc ccctttcggg tgtccttact cacatagaca   3000

tgccacctac ccttaccgag tgtgctctgt gaatcctcct tcagccatag aaatgcagtt   3060

gcgaagagta ttacatgata ttagaaactc actgcagaat ctttcacagt accctatgat   3120

gagaggacct gatcctgctg ctgctccata tagtactcag aaatcatctg ttctacctct   3180

ttatgaaaat acttttcagg agctccaggt aatgaggcgg agcctgaatt tgtttagaac   3240

acaaatgatg gatttagaat tggcaatgct gcgtcagcaa accatggttt atcatcatat   3300

gactgaggag gagaggtttg aagttgatca gctccagggt ttgagaaatt cagtccgaat   3360

ggaacttcag gacctggaac tgcagctgga ggagcgcctg ctgggcctgg aggagcagct   3420

tcgtgctgtg cgcatgcctt cacccttccg ctcctccgca ctcatgggaa tgtgtggcag   3480

tagaagcgct gataacttgt catgcccttc tccattgaat gtaatggaac cagtcactga   3540

actgatgcag gagcagtcat acctgaagtc tgaattgggc ctgggacttg gagaaatggg   3600

atttgaaatt cctcctggag aaagctcaga atctgttttt tcccaagcaa catcagaatc   3660

atcttctgta tgttctggtc cctctcatgc taacagaaga actggagtac cttctactgc   3720

ctcagtgggc aaatccaaaa ccccattagt ggcaaggaag aaagtgttcc gagcatcggt   3780

ggctctaacg ccaacagctc cttctagaac aggctctgtg cagacacctc cagatttgga   3840

aagttctgag gaagttgatg cagctgaagg agccccagaa gttgtaggac ctaaatctga   3900

agtggaagaa gggcatggaa aactcccatc aatgccagct gctgaggaaa tgcataaaaa   3960

tgtggagcaa gatgagttgc agcaagtcat acgggagatt aaagagtcta ttgttgggga   4020

aatcagacgg gaaattgtaa gtggactttt ggcagcagta tcttcaagta aagcgtctaa   4080

ttctaagcaa gattatcatt aaacagaaat tataggttgg catggatcct attagctgtg   4140

taatactgga attatcaatg atatgcactg gtggaggtgt tatttgtgct ttagaagata   4200

cttgctgttg agctgggcta ctgtatacag tgtacaatgt gtatttcttc aaccatatat   4260

tttaaaaaga cgtacataga aacttaggca ctttgctatt tcttttctaa actatcaaaa   4320

actctagcag tttgaaaagc ctaatattta tttgtatgtc agtatttttc atttgattcc   4380

ctattagaat taattttaaa acttgaagac ttccagactt atccaactta taaataacat   4440

atttcttcag actaacatct taaaacactg acctctatga ggtatttact gtgcaataac   4500

tgattcattt ttttcagagc ttgaagcatc caatgatttt tccctccact gctgttaatt   4560

aatgtcactt ccaagaagaa aaactgttct gttgtaaaaa atataattgc tcttaattct   4620

tggggaggtt actaatagca gtaggataga attttatgag gttacctaca actacttaat   4680

gtacttacac tgtaagcctt gttgctttac ccaagacaaa tgtaatttta tcattgctta   4740

tgtagtattt ttcttttgga aatgtgcctt atgttaaaca ctatgtactt ttactttttg   4800

cattgtccag acttctttat tagatggaga tgtttctttt tctgtcttct agactaaata   4860

gagtatcatc caaataatgg ggcctatgac ttgaatgaat agaaatgaat aagctggtgt   4920

ttgttttttc aaaatggaag taatttagat ttgttctcct catacataaa atgattttag   4980

ttcagtttta accagtgaaa actttgtttt tatgaaaaaa aaggaaaatg gtttcccatt   5040

tggttttata tgtgttaaat aaatgtgtaa agtaaccacc aaatgttatt agaatttttc   5100

ttctagcatt tataattttt tcaactccta ttgtgtttct ttgtgtgtga tattttaatc   5160

aaaagtggtt gagttgttaa cagtgttctt tgaaagaatc tctaaaaggc ttataaatgt   5220

ttgaaatatc acacaaaggc tgatttctaa aatatatata tattaaaaca ataaagtatt   5280

tattttgcct aaaaaaaaaa aaaaaaaa                                      5308


<210>  872
<211>  2246
<212>  DNA
<213>  Human

<400>  872
gccgctgcgt ccccactatg gcggcgccca tgcagcccag cgcgttgtgg gctcccgccg     60

gggtcccccg cggctgtcgc cgccgcctac gccgctgcct ccgccttcct gccccgcgtc    120

gggccgggcg ccacctcccc cctgcctccc tctccgctgt ggtcatttag gaaatcgtaa    180

atcatgtgaa gatgggactc ttggtatttg tgcgcaatct gctgctagcc ctctgcctct    240

ttctggtact gggatttttg tattattctg cgtggaagct acacttactc cagtgggagg    300

aggactccaa gtatgatcgg ttgggcttcc tcctgaatct ggactctaaa ctgcctgctg    360

aattagccac caagtacgca aacttttcag agggagcttg caagcctggc tatgcttcag    420

ccttgatgac ggccatcttc ccccggttct ccaagccagc acccatgttc ctggatgact    480

cctttcgcaa gtgggctaga atccgggagt tcgtgccgcc ttttgggatc aaaggtcaag    540

acaatctgat caaagccatc ttgtcagtca ccaaagagta ccgcctgacc cctgccttgg    600

acagcctccg ctgccgccgc tgcatcatcg tgggcaatgg aggcgttctt gccaacaagt    660

ctctggggtc acgaattgac gactatgaca ttgtggtgag actgaattca gcaccagtga    720

aaggctttga gaaggacgtg ggcagcaaaa cgacactgcg catcacctac cccgagggcg    780

ccatgcagcg gcctgagcag tacgagcgcg attctctctt tgtcctcgcc ggcttcaagt    840

ggcaggactt taagtggttg aaatacatcg tctacaagga gagagtgagt gcatcggatg    900

gcttctggaa atctgtggcc actcgagtgc ccaaggagcc ccctgagatt cgaatcctca    960

acccatattt catccaggag gccgccttca ccctcattgg cctgcccttc aacaatggcc   1020

tcatgggccg ggggaacatc cctacccttg gcagtgtggc agtgaccatg gcactacacg   1080

gctgtgacga ggtggcagtc gcaggatttg gctatgacat gagcacaccc aacgcacccc   1140

tgcactacta tgagaccgtt cgcatggcag ccatcaaaga gtcctggacg cacaatatcc   1200

agcgagagaa agagtttctg cggaagctgg tgaaagctcg cgtcatcact gatctaagca   1260

gtggcatctg agtgggccca gcacatggcc atagaggccc aggcaccacc aggagcagca   1320

gccagcacca cctacacagg agtcttcaga cccagagaag gacggtgcca agggccccag   1380

gggcagcaag gccttggtgg agcagccaga gctgtgcctg ctcagcagcc agtctcagag   1440

accagcactc agcctcattc agcatgggtc cttgatgcca gagggccagc aggctcctgg   1500

ctgtgcccag caggcccagc atgcaggtgg tgggacactg ggcagcaagg ctgctgccgg   1560

aatcacttct ccaatcagtg tttggtgtat tatcattttg tgaatttggg taggggggag   1620

ggtagggata atttattttt aaataaggtt ggagatgtca agttgggttc acttgccatg   1680

caggaagagg cccactagag ggcccatcag gcagtgttac ctgttagctc cctgtggggc   1740

aggagtgcca ggaccagcct gtaccttgct gtggggctac aggatggtgg gcaggatctc   1800

aagccagccc cctccagctc atgacactgt ttggcctttc ttggggagaa ggcggggtat   1860

tcccactcac cagccctagc tgtcccatgg ggaaaccctg gagccatccc ttcggagcca   1920

acaagaccgc cccagggcta tagcagaaag aactttaaag ctcaggaggg tgacgcccag   1980

ctccgcctgc tgggaagagc tcccctccac agctgcagct gatccatagg actaccgcag   2040

gcccggactc accaacttgc cacatgttct aggtttcagc aacaagactg ccaggtggtt   2100

gggttctgcc tttagcctgg accaaaggga agtgaggccc aaggagctta cccaagctgt   2160

ggcagccgtc ccaggccacc cccatggaag caataaagct cttccctgag cctggaaaaa   2220

aaaaaaaaaa aaaaaaaaaa aaaaaa                                        2246


<210>  873
<211>  27439
<212>  DNA
<213>  Human

<400>  873
cggccgccgg ccgcagcggg ctgagattgt tgtcctctgt caccagggcg gctgggctcc     60

cgcagtcctg cagaccgcgc ccgatcccgg cgacagggcg ggcggacagc cgcgcatccc    120

cggggtcccg ccgagcctgg gcgcagagag ccgggaggaa gcgttcgctc gcttcgcctt    180

gctgctggga aactgaacga ggccgagaga gaaggttctt gagttcatgt aagaggacag    240

tcttaaaacg gaagaagaaa aagaagcagt tcagtctttg ggagagctgc ctccttgttg    300

agtgctgcaa aggcctggaa ttcatttatg acagaataga tctagaaaag tccaagcatg    360

ttttctagag tggtgtagcc ctgtgctgcc tccagtgaag agtctcttgg tgttggcttc    420

gtgcttccgg agggaccatg gcaacctcca gaggggcctc ccggtgtcct cgggatatcg    480

ccaatgtgat gcagaggctg caagatgagc aagagatagt acaaaaacga actttcacaa    540

aatggatcaa ctctcatctg gccaagcgga aacctccaat ggtggtggac gatctttttg    600

aagacatgaa agatggtgtt aaactgcttg cccttctgga ggtcctgtct gggcagaaac    660

tgccttgtga acaaggacgc cggatgaagc gaatccatgc tgtggctaac attggcacgg    720

cactcaagtt cctcgaagga agaaagtcca tgcacagagg atcaccgatt aaattagtca    780

acattaactc caccgatata gctgatggcc gaccctcaat agttcttgga ttgatgtgga    840

ccattattct atatttccag attgaagagt tgaccagcaa cctgccccag ctccagtctt    900

tgtccagcag cgcatcctcc gtggacagca tagttagctc tgagactccc agcccaccaa    960

gtaaacggaa ggtgaccacc aagatccaag gaaatgctaa gaaggcttta ttaaagtggg   1020

ttcagtacac agctggcaag cagactggaa tagaagtaaa agattttggg aagagttgga   1080

gaagcggggt tgcctttcat tcagttattc atgccattcg accggaattg gtggacttgg   1140

agacagtgaa aggcagatcc aaccgagaaa atttggagga tgctttcact atcgccgaaa   1200

cagaactggg gatcccaaga ctgctagatc ctgaagacgt tgatgtggat aaaccagatg   1260

agaaatctat tatgacctat gtagcccagt ttctgaaaca ttatcctgac atccacaatg   1320

caagcactga tgggcaagag gatgatgaaa tacttccagg tttcccatct tttgcaaatt   1380

ctgtacaaaa ttttaagaga gaagacagag taatttttaa ggaaatgaaa gtttggatag   1440

aacaatttga gagagatttg acaagagcac agatggtgga atcaaattta caggataaat   1500

atcagtcatt taagcacttc agagttcaat atgaaatgaa gaggaaacag attgaacatt   1560

taatacaacc attacacaga gacggtaaat tgtcacttga ccaagcattg gtaaaacaat   1620

cttgggatag agtgacctcc aggctctttg actggcatat acagcttgat aaatctcttc   1680

ctgcacctct gggcaccata ggtgcctggc tgtacagagc ggaggtggcc ctgagagagg   1740

aaataaccgt tcaacaggtc cacgaggaaa cagcaaacac gatacaacgg aaacttgagc   1800

aacataagga tctgcttcaa aacacggatg cccacaaaag agcattccat gaaatctacc   1860

ggaccaggtc tgttaacggg attccagtgc cacctgatca attagaggac atggccgaga   1920

ggtttcattt tgtttcctcc acatcagagc tacacctaat gaaaatggaa tttttagaat   1980

taaagtaccg tctgctctca ctgctggttc ttgcagagtc aaagctgaag tcttggatca   2040

ttaagtacgg gaggagagag tcagtggagc agcttctaca aaactacgtg tcttttatag   2100

aaaatagcaa gttctttgaa caatatgagg tgacatacca gatcttgaaa cagacagctg   2160

agatgtatgt caaagcagat ggttcagtgg aagaagctga gaatgtgatg aaattcatga   2220

atgaaaccac cgctcagtgg aggaatctct cagtagaagt gaggagtgtg aggagcatgc   2280

tggaagaagt gatctctaac tgggatcgct atggcaatac agtggctagt ctgcaagcct   2340

ggctagagga tgctgaaaaa atgctcaatc aatcagaaaa tgccaaaaag gatttttttc   2400

gaaatttacc tcattggatt cagcagcata ctgccatgaa cgatgctggc aattttctaa   2460

ttgaaacctg tgatgagatg gtttcccgtg acctgaagca gcaattactg ttgctaaatg   2520

ggcggtggag ggagttgttt atggaagtca agcaatatgc tcaagctgat gagatggaca   2580

gaatgaagaa ggaatacaca gactgtgttg ttaccctgtc tgcttttgca acggaagccc   2640

ataagaaact ttctgaaccc ttagaagtct cttttatgaa tgtcaagcta ttaattcaag   2700

acttggagga tattgagcag agggtgcctg tgatggatgc ccaatacaag ataattacaa   2760

agacagcaca cctcattacc aaagaaagcc cccaagaaga aggaaaagaa atgtttgcga   2820

ccatgtcaaa gctcaaagag cagctaacca aggtcaaaga atgttactcc ccactccttt   2880

atgagtctca gcagctgttg attccgttgg aggaattaga aaagcagatg acgtcctttt   2940

atgactcact tgggaaaatc aatgaaatta tcacagttct tgagcgtgag gcacaatcga   3000

gtgccctttt taaacaaaaa catcaggaac tgttagcttg tcaagaaaac tgtaagaaaa   3060

ccttgacact tattgagaaa ggcagtcaaa gtgttcaaaa gtttgtgacc ttgagcaacg   3120

tgttaaagca ttttgatcag acgaggctac aaagacagat tgcagatatt catgttgctt   3180

ttcagagtat ggtaaagaaa actggagatt ggaagaagca tgtggaaacc aacagtcgct   3240

tgatgaagaa gtttgaggag tctcgagcag agttggagaa ggtactgcgg attgctcagg   3300

agggcctgga ggaaaagggg gatccagagg agctcctgcg gagacacact gagtttttca   3360

gtcagctgga tcagagggtg ctcaatgctt tcctgaaagc ttgtgatgaa ctcaccgaca   3420

tccttccaga gcaggagcag caggggctgc aggaagctgt tcgaaagctc cacaaacaat   3480

ggaaggatct tcaaggagaa gccccttatc atttgcttca tctgaagatt gatgtggaga   3540

agaataggtt cttagcctct gtagaagaat gcagaactga gctggatcga gagaccaagc   3600

tgatgcccca ggaaggcagt gaaaagataa ttaaagagca cagggttttc ttcagtgaca   3660

aaggtcctca tcatctctgt gagaaaaggt tacagctcat cgaggaactc tgtgtgaaac   3720

tcccagtgcg ggacccagta agggacacac ctggaacctg tcacgtgact ctcaaagagc   3780

tcagagctgc cattgacagc acctacagga agctcatgga agacccagac aagtggaagg   3840

actacactag cagattctct gagttctcat cttggatatc tacaaatgag acacaattaa   3900

aggggatcaa gggtgaggcc atcgatactg ccaaccacgg agaggttaaa cgtgccgttg   3960

aagagatcag aaatggtgtt accaaaaggg gtgagaccct cagctggctg aaatccaggc   4020

tgaaagtttt gacagaagtt tcttctgaga atgaagccca aaagcaggga gatgagctgg   4080

caaaattatc cagctctttc aaggctcttg tgacgctgct gtcagaggtt gaaaagatgc   4140

taagcaattt tggggactgt gtccagtaca aagaaatagt caaaaattct ctcgaagaat   4200

taatttctgg ctctaaagaa gtccaggaac aagctgagaa gatcttggat actgaaaatc   4260

tgtttgaagc acagcagtta cttcttcatc accagcaaaa gacaaagcgg atctcagcaa   4320

agaagagaga tgtgcagcag cagatcgcgc aggcgcagca gggagaaggg gggctgcctg   4380

accgaggcca cgaggagctg cggaagctgg agagcacact ggatggcctg gagcgcagcc   4440

gggagaggca ggaacgccgc atccaggtca cattaagaaa atgggagcga tttgaaacaa   4500

acaaagaaac agtagtaaga tacctttttc aaacaggttc cagtcatgaa cgcttcttga   4560

gttttagcag tttggaaagt ttatcttcag aactggaaca aacaaaggag ttttctaaac   4620

ggacagaaag tattgcagtc caggctgaga accttgtaaa ggaagcttca gagataccgc   4680

ttgggcccca aaataagcag ctgcttcaac agcaggccaa gtcaatcaaa gaacaagtca   4740

aaaaattaga agacacgctt gaagaagata ttaaaaccat ggaaatggtg aaaaccaagt   4800

gggatcattt tggcagtaat tttgagactc tgtccgtctg gataactgag aaagaaaaag   4860

aactcaatgc cttggaaact tcgtcatctg ccatggacat gcaaatcagc caaattaagg   4920

tcacaattca ggaaatagaa agtaagctca gcagcattgt aggattagaa gaagaagccc   4980

agtcttttgc tcagtttgtt accactggag aatctgctcg aattaaagcc aagttgacac   5040

aaataagaag atacggggaa gagcttcgag agcatgcaca gtgtctggaa ggaacaatcc   5100

tgggacattt atctcagcag caaaagtttg aagagaacct tagaaagatc cagcaatctg   5160

tgtctgaatt tgaagataaa cttgctgttc caattaaaat atgttcttca gctacagaaa   5220

catacaaagt tcttcaagaa catatggatc tctgccaggc cctggagtca ctgagcagcg   5280

cgatcactgc cttctcagcc agtgccagga aggttgtgaa cagagattcc tgtgttcagg   5340

aggctgcggc tctacagcag caatacgagg acatcctaag gagggcgaag gagagacaga   5400

cggcgctgga gaatctgctg gcccactggc agaggctaga gaaagaacta tcatcctttt   5460

tgacctggtt agagcggggt gaagctaaag ccagttcccc agaaatggac atttctgcag   5520

acagagtcaa agtggaaggt gaacttcagt taatacaggc actgcaaaat gaagttgtat   5580

cccaggcctc attctatagc aaacttttgc aattgaagga atcattgttc tcagtagcct   5640

ccaaagatga tgtgaaaatg atgaaactac atttggagca gttggatgag agatggagag   5700

atttaccaca gatcattaac aaaaggatta attttcttca gtctgtggtt gctgaacacc   5760

agcaatttga tgagctgctg ctttcctttt ctgtctggat taaactgttt ctcagtgaat   5820

tacaaactac ctctgagatt agcataatgg accatcaagt agcccttact cggcataagg   5880

accacgcagc agaagtagag agcaaaaagg gcgaattgca gagtctgcag ggtcacttag   5940

caaagttggg ttctctgggc cgtgctgagg acctccacct cctgcaggga aaggctgagg   6000

actgcttcca gctgtttgag gaggccagcc aggttgtgga gaggcggcag cttgccctgt   6060

cccatttggc agaattcctc cagagccatg cctctctgtc cggcattctc cgccagctga   6120

ggcaaacagt ggaagcaacc aacagtatga ataagaacga gtctgatttg atagaaaagg   6180

acctcaatga tgctcttcaa aatgctaaag cattagaatc tgctgccgtc agtctggatg   6240

gcattctttc caaagcccaa taccatctga aaatcgggag ctctgagcaa aggacttcct   6300

gcagagccac ggctgatcag ctctgtggag aggtagagag gatccagaac cttctgggaa   6360

ccaagcagag tgaggcagat gctctggcag tgttgaaaaa agcattccaa gaccagaaag   6420

aggagcttct gaaaagcatt gaggacattg aagaaaggac tgacaaagag cgattgaaag   6480

aacctacccg ccaagctctt cagcagaggt taagagtgtt taatcagcta gaagatgaat   6540

tgaattctca cgagcatgaa ctatgttggt tgaaagacaa agccaagcaa attgcccaga   6600

aagatgtagc ttttgcacct gaagttgaca gggagataaa ccgcttagag gtcacctggg   6660

atgataccaa aagactaatt catgaaaatc agggtcagtg ctgtggactt attgacttaa   6720

tgagagaata tcagaacctg aaatcagctg tatctaaagt cttagaaaat gccagcagtg   6780

tgattgtaac cagaactacc ataaaagatc aggaggatct taaatgggct ttttccaagc   6840

atgaaactgc caagaacaaa atgaattaca aacagaaaga cttggataac tttaccagca   6900

aaggaaaaca cttgttatct gagctgaaga aaattcacag tagtgatttc agcttggtga   6960

aaacagacat ggagagcacc gtggacaaat ggctggatgt atcagagaaa cttgaagaaa   7020

acatggatag gctgagagta agcctgtcca tttgggatga tgtactgtca actagagatg   7080

agattgaggg atggtcaaac aactgcgttc cacagatggc agaaaacatc agcaacctgg   7140

ataaccacct cagagctgaa gaactgctta aagaatttga gtctgaagtt aaaaacaaag   7200

cattgagatt ggaagaactg cattccaaag ttaatgatct gaaagaatta actaaaaatc   7260

tagaaacacc gccagacctt cagtttatag aagcagactt aatgcagaaa ctggagcatg   7320

ccaaagaaat aactgaagta gcaaaaggaa ccctgaagga tttcacggct caaagtacac   7380

aagtggagaa gtttattaat gacataacaa catggttcac aaaagtggaa gaatcgttga   7440

tgaactgtgc ccaaaatgag acttgtgaag cattgaaaaa agtcaaggat atacaaaaag   7500

aacttcaaag tcaacaaagc aacatcagct ctacccaaga aaatctcaat agcttgtgcc   7560

gcaagtacca ctcagctgag ttggagagcc tgggccgtgc aatgactggt ctgataaaga   7620

aacatgaagc cgtgagccag ttgtgctcca aaacccaggc cagcctgcag gaatctctgg   7680

aaaaacactt cagtgagtct atgcaggaat tccaagaatg gtttttggga gcaaaggcag   7740

cagcaaaaga atcatcagat cgcaccggtg acagcaaagt tctagaagca aagctccatg   7800

atcttcagaa cattttggac tcagtcagtg atgggcagag caaacttgat gcagtgactc   7860

aagaaggaca aactttgtat gcacatttgt ctaaacaaat tgtcagtagc attcaagaac   7920

aaatcacaaa ggccaatgaa gagtttcaag catttctgaa acaatgcctt aaagataagc   7980

aggctcttca agactgtgct tcagaacttg gaagctttga agatcagcac agaaaactga   8040

acttatggat ccatgaaatg gaagaaaggt tcaatacgga aaacttggga gagagtaaac   8100

agcacattcc tgagaagaaa aatgaagttc ataaagttga aatgtttttg ggagaactgc   8160

tggctgcaag agagtctctt gataagcttt cccagagagg gcagcttctg agtgaagaag   8220

gccacggtgc tgggcaggag ggccgcctgt gttcccagct cctcacaagc caccagaacc   8280

tacttagaat gaccaaagag aaactccgga gctgccaggt ggcccttcag gagcacgaag   8340

ccctggagga agcactgcaa agcatgtggt tctgggtgaa ggccattcag gacagactgg   8400

cctgtgcaga gagcactctt gggagcaaag acaccctgga gaaacggctg tcacaaatac   8460

aggatattct cctgatgaaa ggtgaagggg aagttaagtt gaatatggcc attggcaagg   8520

gggaacaggc cttgagaagt agcaacaaag aaggtcagag ggtgattcag actcagttag   8580

agacccttaa agaagtgtgg gctgacatca tgagctcctc cgtccacgct caaagcactt   8640

tagagtctgt gattagccaa tggaatgact atgtagagag gaaaaaccag ttggagcagt   8700

ggatggaatc agtggatcaa aaaatagaac atcccttaca accacagcca ggtctgaaag   8760

agaagttcgt cctgcttgac cacctccagt ccatcctgtc tgaggcagaa gatcacacga   8820

gagcccttca ccgtctaatt gcgaagtcca gggagctcta cgaaaagaca gaggatgagt   8880

ctttcaagga cacagctcaa gaggagctga aaacacagtt taatgatata atgactgttg   8940

ccaaggaaaa aatgaggaaa gtggaagaga ttgtgaaaga tcatctaatg tatttagatg   9000

cggtccacga gttcacagat tggctccatt cagcaaagga agaacttcac cggtggtcag   9060

atatgtctgg agattcatca gccacccaga aaaagttatc aaaaattaag gagctgatag   9120

attccagaga gattggtgca agccgtctca gcagagtgga gtcgctggct cccgaagtga   9180

aacagaacac aactgccagt gggtgtgagc tcatgcacac ggagatgcag gccctgcgtg   9240

ccgactggaa gcagtgggaa gacagtgtat tccaaacgca gagctgtttg gagaacctgg   9300

tcagccagat ggccctttcg gagcaggaat tctcaggcca agtggctcaa ctggagcagg   9360

ccctggaaca gttcagtgcc cttctgaaaa cctgggctca gcagttaacc ctcctggaag   9420

gcaagaacac ggatgaggag atagtggaat gctggcacaa aggacaagag atactggatg   9480

ctttgcaaaa agcagagcct agaacagagg atctcaagtc tcagctgaat gaactttgtc   9540

gattttccag agacctgagt acctacagtg gaaaagtttc tggcttgatt aaagagtata   9600

attgtctttg tttgcaagca tccaagggct gccagaataa agaacagatt ttacagcaaa   9660

gatttcgaaa ggccttcagg gatttccagc agtggttggt taatgcaaaa atcactaccg   9720

ccaagtgttt tgatatacct caaaatataa gtgaagtttc aactagtctt cagaaaatac   9780

aggagttttt gtcagaaagt gaaaatggac agcacaagct aaacatgatg ctgtctaaag   9840

gggaacttct gagtaccctg ctgaccaaag agaaagcgaa agggatccag gccaaagtta   9900

cagctgcaaa agaagattgg aaaaattttc attcaaatct ccaccaaaaa gaatctgctc   9960

tagagaatct aaagatccaa atgaaggact ttgaagtaag tgctgagcct atccaggact  10020

ggctgagtaa aactgagaag atggtccatg aaagcagcaa tcgcctctat gatctgccag  10080

caaagaggag ggagcagcag aagctccagt ctgtccttga ggaaatacac tgctacgagc  10140

ctcagctcaa caggctgaaa gagaaagctc agcagctgtg ggaaggacaa gctgccagca  10200

agagctttag gcacagagtg tcgcagctgt cttctcagta tctagcgcta agcaatttaa  10260

caaaggagaa agtgtcaaga ctggatagaa tcgttgcaga acacaatcag ttctctcttg  10320

ggattaaaga attacaagac tggatgacgg atgcgattca catgctggat tcatactgcc  10380

acccgacatc cgacaaaagt gtgctggaca gcaggacgct caagctcgag gctctattat  10440

cagtcaaaca ggaaaaagag attcagatga aaatgatagt gaccagggga gaatctgtcc  10500

ttcagaatac ttctccagaa ggcattccca ctattcagca gcagctgcag agtgtgaagg  10560

atatgtgggc atcccttttg tctgcaggga ttcgttgtaa aagccaactc gaaggagctc  10620

tctccaagtg gacaagttat caggatggcg ttcgacagtt ctccggttgg atggatagta  10680

tggaagccaa cctgaatgaa tcagaaaggc agcatgcgga gctgcgggat aaaacaacga  10740

tgctcggaaa agccaagtta ttaaatgaag aagtgctgag ttacagcagc ttgctggaga  10800

ccatcgaagt caaaggggct ggcatgacag aacactatgt cacccagcta gaactccagg  10860

atctacagga acgatacaga gccatccaag agagggccaa ggaagccgta accaagtctg  10920

aaaaacttgt ccgcctgcac caagagtatc agagagacct aaaggcattt gaagtttggt  10980

tggggcaaga acaagaaaag ctcgaccagt attcagttct tgaaggtgat gcccacactc  11040

atgagacaac attgcgtgat cttcaggagc tacaggtaca ctgtgcagag gggcaggccc  11100

tgttgaactc agtgctgcac accagagagg atgtgatccc atcaggtatc ccacaggcag  11160

aggaccgggc tttagagtct ctccggcaag actggcaggc ttaccagcac aggctgtccg  11220

agactcgaac tcagttcaat aacgtggtga acaaattgag gctaatggag caaaagtttc  11280

agcaagtaga tgaatggctc aaaacagcag aggagaaaaa gtggcacgaa gaagtgactg  11340

catacagaga tgaagttgag gaagtgggag ctagagctca ggagatactg gacgagagcc  11400

acgtgaacag cagaatgggt tgccaggcca cccagctgac ttccagatac caggccctgc  11460

ttctccaagt gctggaacaa ataaaattcc tggaggagga gattcagagt ttggaggaat  11520

cagaatcatc cctcagttcc tattctgatt ggtatggctc tactcataaa aacttcaaga  11580

atgtggctac caagattgac aaagtagata cagtaatgat ggggaagaaa ttgaagacgt  11640

tggaggtttt gctcaaagac atggagaaag gtcacagttt gctgaaatca gcccgggaga  11700

aaggagagag ggctgttaaa tacttggagg aaggcgaggc agagaggtta agaaaggaga  11760

ttcatgatca catggagcag ttgaaggaac tgaccagcac tgtccggaaa gaacacatga  11820

cgctggaaaa aggtcttcat ttagcaaagg aattctcaga taaatgcaaa gcactgacac  11880

agtggatagc agaataccag gaaattctac atgttcctga agaacccaaa atggaattat  11940

atgagaaaaa agctcagtta tctaaataca agtcacttca acaaacggtg ctgtcccatg  12000

aaccatcagt aaagtcagtg agagagaagg gtgaagctct tttggaactg gtgcaggacg  12060

tcactttaaa ggacaaaata gatcaacttc aaagtgatta ccaggacctg tgcagcatag  12120

gaaaggcaat gatggaagaa attgctggtt ttgaagaccg tttgaacaat cttcaaatga  12180

aaggtgatac tttgattggc caatgtgcag accacctgca agcgaaactt aaacaaaacg  12240

tgcatgctca tctgcagggc acaaaggaca gctactcagc gatctgcagc acagctcaga  12300

ggatgtacca gagtttggaa cacgaacttc agaagcacgt cagccgacaa gacaccctgc  12360

agcagtgcca ggcctggctt tctgcagtcc agccggattt agagccaagt cctcaaccac  12420

ctcttagtag ggcagaagcc attaagcagg tcaaacactt cagagctttg caagagcagg  12480

caaggaccta cctagatctc ctttgctcca tgtgtgacct gtcaaatgct tcggtgaaaa  12540

ccacagcaaa agacattcaa caaacagagc aaacgattga acaaaagctt gtccaggccc  12600

agaacttaac tcagggctgg gaagagatca agcacctgaa gtctgagctc tggatttacc  12660

tgcaagatgc tgatcagcaa ctgcagaaca tgaagaggag gcactctgag ctggagctga  12720

acattgcaca gaacatggtt tcacaagtta aggattttgt taagaaacta cagagcaaac  12780

aggcatccgt gaacaccata atagaaaagg tgaataagtt aacaaagaag gaggaatcgc  12840

ctgaacacaa ggaaataaat catttaaatg atcagtggct cgatttgtgc cgtcagtcta  12900

acaacctgtg cttgcaaagg gaagaggatc ttcagagaac aagagattac catgactgta  12960

tgaatgttgt tgaagtgttc ctagaaaaat ttactacaga atgggataac ttggccagat  13020

ctgatgcaga gagtacagct gtccacctgg aagctttgaa aaagttagca ttggcattgc  13080

aggagagaaa gtatgctatt gaagatctga aagatcaaaa gcagaaaatg atagagcatc  13140

tgaatttaga tgacaaggag ttagtcaaag aacagacgag tcatttagag caacgttggt  13200

ttcagcttga ggacctcatt aaaaggaaaa tccaagtgtc agtcaccaac ttggaggagt  13260

taaatgtggt gcagtccaga tttcaggagc taatggagtg ggcagaagag caacaaccca  13320

acatcgccga ggcccttaag cagagccctc ctccagatat ggctcagaac cttctcatgg  13380

atcacctggc catctgcagt gaactggagg ccaagcagat gctcctgaaa tcgcttataa  13440

aggacgcaga cagggtcatg gcagatcttg gtctcaatga gcgacaggtc atccagaagg  13500

ctctctctga tgcacaaagc cacgtgaatt gtctcagtga cttagtgggc cagcgaagaa  13560

agtacttaaa caaagccttg tccgagaaaa cccagtttct catggcagtg ttccaggcca  13620

ccagccaaat tcagcaacat gagcgaaaga taatgttccg tgaacacatc tgtctgttac  13680

cagatgatgt gagcaaacaa gtcaaaacat gtaagagtgc acaagccagc ctcaagactt  13740

accaaaatga agtcactgga ctttgggccc agggtcgcga actaatgaag gaagtcacag  13800

agcaggaaaa gagtgaagtg ctggggaagc ttcaggaatt gcagagtgtc tatgacagtg  13860

ttttacaaaa gtgcagtcac cggttacaag aactagagaa gaatttggtt tctaggaagc  13920

attttaagga agattttgat aaagcttgcc actggctaaa acaagcagat attgttacat  13980

ttcctgaaat caacctaatg aatgagagtt ctgagcttca tacacaactg gctaaatacc  14040

aaaacattct tgaacaatct ccagaatatg aaaatcttct acttacgctg cagagaactg  14100

ggcagaccat attaccatcg ctgaatgaag tcgatcattc ctacctcagt gaaaagctaa  14160

atgctttgcc tcgacaattt aatgtaattg ttgccttggc taaagacaag ttctataaag  14220

tccaggaagc aattcttgct cggaaggaat atgcttcctt gattgagttg acaacccagt  14280

ctctgagtga acttgaagcc caattcttga ggatgagcaa agttcccacc gacctggccg  14340

ttgaggaggc tctttctctg caagatggtt gcagagccat tctggacgag gtggcgggcc  14400

ttggggaggc ggtggatgaa ctgaaccaga aaaaagaagg ttttcgcagc acaggtcagc  14460

cttggcagcc agacaagatg ctgcaccttg tcaccttata tcacaggctg aagcgacaaa  14520

cagaacagag ggttagctta ttagaagaca ccaccagtgc ttaccaagaa cacgagaaga  14580

tgtgccaaca gctggagaga caactgaagt ctgtaaaaga ggagcagtcc aaagtgaatg  14640

aggaaacgct gcctgcagag gagaagctca aaatgtatca ctccctggca ggaagtctcc  14700

aggactcagg gattgtactg aaacgagtaa ccatacatct tgaagatctt gccccacacc  14760

ttgacccctt ggcttatgag aaagccaggc atcagatcca gtcctggcaa ggggagttaa  14820

aactgttgac ttctgccatt ggtgagacgg tgacagaatg tgagagccga atggtgcaga  14880

gtatagactt ccagactgag atgagtcgct ccctggactg gctgaggaga gtgaaggcag  14940

agctcagtgg gccggtgtac ctagacctca acctgcagga catccaagag gaaatcagaa  15000

aaatccaaat tcatcaggaa gaggtccagt ccagcttgag aatcatgaat gcgctgagtc  15060

acaaggaaaa ggagaagttc acaaaggcca aggagctgat ttctgcggat ttagaacaca  15120

gcctcgctga gctctcagag ctggatggag acatccagga agccttacgc accagacagg  15180

ctaccttgac tgaaatatat agccagtgtc aaaggtatta tcaggtattt caagcagcca  15240

atgactggct tgaggatgcc caagaattgt tacagctggc aggcaatggc ctagacgtgg  15300

agagcgcaga ggaaaatctc aaaagccaca tggaattttt cagtacagag gatcagttcc  15360

atagtaacct ggaggagctc cacagcctgg tagccaccct ggacccactc atcaagccaa  15420

ccggcaaaga agacctagaa cagaaagtgg cttctctgga actcaggagc cagaggatga  15480

gccgggactc tggtgcccaa gtggatctct tgcagagatg cacagctcaa tggcacgatt  15540

accagaaagc aagggaagag gttattgaat tgatgaatga tacagaaaag aaattgtctg  15600

agttttcttt gttgaagact tcgtctagtc atgaagcgga agaaaaattg tcagaacaca  15660

aggctttagt gtcagtggtt aactctttcc atgagaaaat tgtggccctt gaggaaaaag  15720

cttcacaact ggagaaaacc ggaaatgatg ccagcaaagc caccctgagc aggtcaatga  15780

ccaccgtctg gcagcgctgg acacgccttc gagctgtggc ccaggaccag gagaagatcc  15840

tggaagatgc agtggatgag tggacgggct ttaacaacaa ggttaaaaag gccactgaaa  15900

tgattgatca gctgcaagat aagttacctg gaagttcagc agagaaagca tcgaaagcag  15960

agctcttaac tcttcttgaa taccacgaca cgttcgttct ggagctggag cagcagcagt  16020

cggccttggg catgctgcgg cagcaaaccc tgagcatgct ccaggatgga gccgccccaa  16080

cccctgggga agagcctccg ctcatgcagg aaatcaccgc catgcaagat cggtgcctga  16140

acatgcagga gaaagtgaag actaatggaa agttggtgaa gcaagagctg aaggaccgag  16200

aaatggtgga gactcagatc aattctgtga aatgttgggt tcaggaaacg aaagaatatt  16260

tagggaatcc aacaatagaa atagatgctc aacttgaaga acttcagatt ctcctaacag  16320

aagccacaaa tcaccgacag aacattgaaa aaatggcaga agaacagaag gagaagtact  16380

taggtcttta taccatatta ccttctgaac tctcccttca gttggctgaa gtggcgttag  16440

atctaaagat ccgagatcag atccaagaca aaataaaaga agttgagcag agcaaggcca  16500

cgagccagga actcagccgg caaattcaga agttagctaa agacctcaca actattctaa  16560

ctaagctgaa agcgaagaca gataatgtag ttcaagctaa aactgaccaa aaggtgctgg  16620

gagaggaatt agatggctgt aattcaaagt taatggaatt agatgcagca gtacagaaat  16680

tcttggaaca gaatggccaa ctgggtaagc cactggccaa gaagatagga aaactgactg  16740

aacttcacca gcagaccatt agacaagctg agaatcggct ctccaagctc aatcaggcag  16800

catcacattt agaagaatac aatgaaatgc ttgaattaat tttgaagtgg attgaaaaag  16860

ctaaagtctt ggctcatgga actattgcat ggaattctgc aagccagctt cgggaacaat  16920

atattttgca tcagaccctg ctagaagaat ccaaagaaat tgacagtgag ctggaagcaa  16980

tgactgagaa attacagtac ctcactagcg tgtactgtac agaaaaaatg tctcagcaag  17040

tggcagaact gggacgggag actgaggagt tgcgacagat gatcaaaatt cgtttgcaga  17100

acctccaaga tgcagctaag gatatgaaaa aatttgaagc agagttgaaa aagttacaag  17160

ctgccttgga gcaagcccag gcaacactga cttctccaga agttggacgt ctcagtctca  17220

aggagcagct ctctcatcgg cagcatttgt tgtctgagat ggagtcactg aagccgaagg  17280

tgcaagcagt gcagctctgc cagagtgccc tccggatccc cgaggatgtg gttgccagct  17340

tacctctctg tcatgctgct ctgcggctgc aggaagaggc cagccggctg cagcacaccg  17400

ccatccagca gtgtaacatc atgcaggcag ctgtggtaca atatgaacaa tatgagcaag  17460

aaatgaaaca tctccagcaa ctgatagaag gagctcacag agagattgag gataaacctg  17520

ttgccaccag taacatacag gagctgcagg ctcagatttc tcggcatgag gagctggcgc  17580

agaaaattaa gggctaccag gagcagatcg cttctttgaa ttccaagtgc aagatgctga  17640

cgatgaaagc caagcacgcc accatgctgc tgacggtgac cgaggtcgag gggctggcgg  17700

aagggacaga ggacctggat ggggagctcc tccccacgcc ttcggcccac ccctctgtgg  17760

tcatgatgac tgcaggtcgc tgtcacactt tgctgtcacc ggtcactgag gagtctgggg  17820

aggagggaac caacagtgag atttcctctc cacctgcctg tcgctcccct tcacctgtgg  17880

ctaatacaga tgcttctgtt aaccaggaca ttgcatatta ccaagccttg tctgctgaga  17940

ggttgcagac agatgctgca aaaattcacc ccagcacatc cgcatcccag gagttctatg  18000

aaccgggatt ggagccatcc gctactgcca aactgggtga tttgcagcgt tcttgggaaa  18060

ccttaaagaa tgtgatcagt gagaagcagc gcacactcta tgaagctttg gaacgccagc  18120

agaagtacca ggactccctc cagtccatct ctacgaagat ggaggccatt gagctgaaac  18180

tcagtgagag cccagagcct ggcaggagtc cagaaagcca gatggctgaa catcaggcat  18240

tgatggatga gattctcatg ctccaggatg aaatcaatga gctccagtcc tctctcgcag  18300

aggagctggt atccgagtct tgtgaggccg accctgcgga gcagctggcc ttgcagtcca  18360

cgctcactgt cttagccgag cgaatgtcca ccatcaggat gaaagcctcg gggaaacggc  18420

agcttttgga ggagaagttg aatgatcagc tggaggaaca aaggcaggaa caggccctgc  18480

agaggtatcg ctgtgaagcc gatgagctgg acagctggct cttgagtacc aaggccactc  18540

tggacactgc gctgagtcca cccaaggagc ccatggacat ggaggcccag cttatggact  18600

gccagaatat gctggtggaa atagagcaga aggtggtggc tttatcagaa ctgtcagtcc  18660

acaatgagaa cctgctgctg gagggcaaag ctcacaccaa ggacgaggcc gagcagctgg  18720

ctggaaagct gagaaggctc aaggggagcc tgctggagct gcagagagcc ctgcatgata  18780

agcagctcaa catgcaggga acagcacagg agaaggagga gagcgatgtt gacctaacag  18840

ccacgcagag ccccggcgtc caggaatggc tggcccaagc tcgcaccaca tggacccagc  18900

agcggcagag cagtctccag caacaaaaag agttagaaca ggaattagcc gagcagaaga  18960

gtctccttcg ctcagtagcc agtcgtggag aggagattct aattcaacat tcggcggcag  19020

agacctctgg tgatgctggc gaaaaacctg atgtgttatc ccaggagttg gggatggaag  19080

gggagaaatc atccgctgaa gaccagatga gaatgaaatg ggaaagccta catcaagaat  19140

ttagtaccaa gcagaaacta ctacagaatg ttctggaaca ggaacaagag caagtgcttt  19200

atagcaggcc aaatcgactc ttgtctggtg tgccactgta caaaggggac gtgccaaccc  19260

aagataaatc tgcagttaca tctttgctgg atggactgaa ccaagccttc gaggaggttt  19320

catcccagag tggaggggca aagaggcaga gtatacactt ggagcagaag ttgtatgatg  19380

gagtctcagc cacctctact tggttggatg acgttgaaga acgtttattt gttgccacag  19440

cacttttacc agaagaaaca gagacttgtc tcttcaacca agagattctt gccaaagaca  19500

ttaaggaaat gtctgaagaa atggataaga acaaaaactt gttttcccaa gcttttccag  19560

agaatggtga taatcgagat gttattgaag atactttggg ttgtcttttg ggcaggttat  19620

ccttgctaga ctcagtagtg aatcaacgat gtcatcagat gaaagaaaga cttcagcaaa  19680

tactaaattt ccagaatgat ctgaaagtgc tgtttacatc actggctgac aacaaataca  19740

tcattctgca aaaactggca aatgtgtttg aacagcccgt agcagaacaa atagaggcaa  19800

tacaacaggc tgaagatgga ctcaaagaat ttgatgcagg aatcattgaa ttaaagaggc  19860

gtggtgacaa gctacaggtc gagcagccgt ccatgcaaga actctccaag ctccaggaca  19920

tgtatgatga gctgatgatg atcattggct cccggaggag tggtctgaat cagaacctta  19980

cactcaagag tcagtatgag agggccctac aagatctggc tgacctgcta gaaactggtc  20040

aggagaagat ggcaggagac cagaaaatca tcgtgtcttc caaagaggaa atccagcaac  20100

tacttgacaa acataaggaa tactttcagg gcctggaatc tcatatgatc ttgactgaaa  20160

cactcttcag aaagataatc agctttgcag tccaaaagga aacccagttc catacagagc  20220

tgatggctca ggcttctgct gtactgaaac gggctcacaa gaggggtgtg gagctggagt  20280

acattctaga gacgtggtcc catctggatg aggaccagca ggagctcagc agacagctgg  20340

aggtggtgga aagcagcatc ccaagcgtgg gtctggtgga ggagaacgag gacaggctta  20400

ttgaccgcat aacactctac cagcatttaa aatctagcct taatgaatac cagcccaaat  20460

tatatcaagt attagatgat gggaaacgac ttctgatatc catcagctgc tcagatctag  20520

aaagccaact aaatcaactt ggagagtgct ggctaagtaa caccaataaa atgtctaagg  20580

aacttcacag actggaaaca atattgaaac actggaccag atatcaaagt gaatctgcag  20640

atctaattca ctggttacaa tctgcaaaag accggctaga attttggact cagcaatctg  20700

tgacagtccc acaagagctg gaaatggtcc gtgatcatct aaatgctttc ctggagtttt  20760

ctaaagaagt ggatgcccaa tcttccctga aatcatctgt tctgagtact ggaaatcagc  20820

tccttcgact aaaaaaggtg gacacagcca cgctgcgctc tgagctgtcg cgcattgata  20880

gccagtggac tgacctgcta accaatatcc cagccgtcca ggagaagctc caccagctcc  20940

agatggataa actgccttcc cgccatgcca tttctgaagt catgagttgg atttctctaa  21000

tggaaaatgt tattcagaag gatgaagata atattaaaaa ttccataggt tacaaggcaa  21060

ttcatgaata ccttcagaaa tataagggtt ttaagataga cattaactgt aaacagctga  21120

cagtggattt tgtgaaccag tccgtgctac aaatcagcag tcaggatgtg gaaagtaagc  21180

gtagtgataa gactgatttt gctgagcaac ttggagcaat gaataaaagt tggcaaattc  21240

tgcaaggtct agtaactgag aagatccagc tgttggaagg cttattggaa tcttggtcag  21300

aatatgaaaa taatgtacaa tgtctgaaaa catggtttga aacccaggaa aagagactaa  21360

aacaacagca tcgaattgga gatcaggctt ctgttcaaaa tgcactgaaa gactgtcagg  21420

atctggaaga tttgattaaa gcaaaagaaa aagaagtaga gaaaattgag cagaatggac  21480

ttgctttgat tcagaacaag aaagaagacg tctctagcat tgtcatgagc acactgcgag  21540

agctcggcca aacctgggca aatttagatc acatggttgg acaattaaag atactgctga  21600

aatcagtgct tgaccaatgg agtagtcaca aagtggcctt tgacaagata aacagttacc  21660

tcatggaggc cagatactct ctttcccgat tccgtctgct gactggctcc ttagaagctg  21720

tgcaagttca ggtggacaat cttcagaatc tccaagatga tctggaaaaa caggaaagga  21780

gcttacagaa atttggctct atcaccaacc aattattaaa agagtgtcac ccacccgtga  21840

cagaaactct taccaataca ctgaaagaag tcaacatgag atggaataac ttgctggaag  21900

agattgctga gcagctacag tccagcaagg ccctacttca gctttggcaa agatacaagg  21960

actactccaa acagtgtgct tcgacagttc agcagcagga ggatcgaacc aatgagctgt  22020

tgaaggcagc cacaaacaag gacattgccg atgatgaggt tgccacatgg attcaagatt  22080

gcaacgacct cctcaaagga ctgggcacag ttaaagattc cctctttttt ctccatgagc  22140

tgggagagca actgaagcaa caagtggatg cttccgcagc atcagctatt caatcggatc  22200

aactctcttt gagtcaacac ttgtgtgccc tggagcaagc tctctgcaaa cagcagactt  22260

cattacaggc tggagttctt gattatgaaa cctttgccaa gagtttagaa gctttggagg  22320

cctggatagt ggaagctgaa gaaatactac aagggcagga ccctagccac tcatctgacc  22380

tctccacaat ccaggaaagg atggaagaac ttaagggaca gatgttaaaa ttcagcagca  22440

tggctccaga tttagaccgt ctaaatgagc ttggatatag gttacccttg aatgataagg  22500

aaatcaaaag aatgcagaat ctgaaccgcc attggtctct gatctcctct cagactacag  22560

aaagattcag caagttgcag tcatttttgc tacaacatca gactttcttg gaaaaatgtg  22620

aaacatggat ggaattccta gttcagacag aacaaaagtt agcagtagag atttcaggaa  22680

attatcagca ccttttggaa cagcagagag cacacgagtt gtttcaagcc gagatgttca  22740

gtcgtcagca gattttgcac tcaatcatta ttgatgggca acgtcttcta gaacaaggtc  22800

aagttgatga cagggatgaa ttcaacctga aattgacact cctcagtaat caatggcagg  22860

gagtgattcg cagggcccag cagaggcggg ggatcattga cagccagatt cgccagtggc  22920

agcgctatag ggagatggca gaaaagcttc gtaaatggtt ggttgaagtg tcctacctcc  22980

ccatgagtgg tctcggaagt gttcctatac cactgcaaca agcaaggacc ctctttgatg  23040

aagtgcagtt caaagaaaaa gtgtttctgc ggcaacaagg cagctacatc ctgactgtgg  23100

aggctggcaa gcaactcctt ctctcggcgg acagtggcgc tgaggccgcc ttgcaggccg  23160

aactcgctga aatccaagag aaatggaaat cagccagcat gcggctggaa gaacagaaga  23220

aaaaactagc cttcttgttg aaagactggg aaaaatgtga gaaaggaata gcagattccc  23280

tggagaaact acgaactttc aaaaagaagc tttcgcagtc tctcccggat caccatgaag  23340

agctccatgc agaacaaatg cgttgcaagg aattagaaaa tgcagttggg agctggacag  23400

atgacttgac ccagttgagc ctgctgaagg acaccctctc tgcctatatc agtgctgatg  23460

atatctccat tcttaatgaa cgcgtagagc ttctgcaaag gcagtgggaa gaactatgcc  23520

accagctctc cttaaggcgg cagcaaatag gtgaaagatt gaatgaatgg gcagtcttca  23580

gtgaaaagaa caaggaactc tgtgagtggt tgactcaaat ggaaagcaaa gtttctcaga  23640

atggagacat tctcattgaa gaaatgatag agaagctcaa gaaggattat caagaggaaa  23700

ttgctattgc tcaagagaac aaaatacagc tccaacaaat gggagaacga cttgctaaag  23760

ccagccatga aagcaaagca tctgagattg aatacaagct gggaaaggtc aacgaccggt  23820

ggcagcatct cctggacctc attgcagcca gggtgaagaa gctgaaggag accctggtag  23880

ccgtgcagca gcttgataag aacatgagca gcctgaggac ctggctcgct cacatcgagt  23940

cagagctggc caagccaata gtctacgatt cctgtaactc ggaagaaata cagagaaagc  24000

ttaatgagca gcaggagctt cagagagaca tagagaagca cagtacaggt gttgcatctg  24060

tcctcaacct gtgtgaagtc ctgctgcacg actgtgacgc ctgtgccact gatgccgagt  24120

gtgactctat acagcaggct acgagaaacc tggaccggcg gtggagaaac atttgtgcta  24180

tgtccatgga aaggaggctg aaaatcgaag agacgtggcg attgtggcag aaatttctgg  24240

atgactattc acgttttgaa gattggctga agtcttcaga aaggacagct gcttttccca  24300

gctcttctgg ggtgatctat acagttgcca aggaagaact aaagaaattt gaggctttcc  24360

agcgacaggt ccacgagtgc ctgacgcagc tggaactgat caacaagcag taccgccgcc  24420

tggccaggga gaaccgcact gattcagcat gtagcctcaa acagatggtt cacgaaggca  24480

accagagatg ggacaacctg caaaagcgtg tcacctccat cttgcgcaga ctcaagcatt  24540

ttattggcca gcgtgaggag tttgagactg cgcgggacag cattctggtc tggctcacag  24600

agatggatct gcagctcact aatattgaac atttttctga gtgtgatgtt caagctaaaa  24660

taaagcaact caaggccttc cagcaggaaa tttcactgaa ccacaataag attgagcaga  24720

taattgccca aggagaacag ctgatagaaa agagtgagcc cttggatgca gcgatcatcg  24780

aggaggaact agatgagctc cgacggtact gccaggaggt cttcgggcgt gtggaaagat  24840

accataagaa actgatccgc ctgcctctcc cagacgatga gcacgacctc tcagacaggg  24900

agctggagct ggaagactct gcagctctgt cggacctgca ctggcacgac cgctctgcag  24960

acagcctgct ttctccacag ccttcctcca atctctccct ctcgctcgct cagcccctcc  25020

ggagcgagcg gtcaggacga gacaccccgg ctagtgtgga ctccatcccc ctggagtggg  25080

atcacgacta tgacctcagt cgggacctgg agtctgcaat gtccagagct ctgccctctg  25140

aggatgaaga aggtcaggat gacaaagatt tctacctccg gggagctgtt ggcttatcag  25200

atgtaatgat ccccgaaagc cctgaggcct atgtaaaact cacagaaaat gcaatcaaaa  25260

atacctccgg ggaccacagt gccctagagt cacagatccg acaactgggc aaagccctgg  25320

atgatagccg ttttcagata cagcaaaccg aaaatatcat tcgcagcaaa actcccacgg  25380

ggccggagct agacaccagc tacaaaggct acatgaaact gctgggcgaa tgcagtagca  25440

gtatagactc cgtgaagaga ctggagcaca aactgaagga ggaagaggag agccttcctg  25500

gctttgttaa cctgcatagt accgaaaccc aaacggctgg tgtgattgac cgatgggagc  25560

ttctccaggc ccaggcattg agcaaggagt tgaggatgaa gcagaacctc cagaagtggc  25620

agcagtttaa ctcagacttg aacagcatct gggcctggct gggggacacg gaggaggagt  25680

tggaacagct ccagcgtctg gaactcagca ctgacatcca gaccatcgag ctccagatca  25740

aaaagctcaa ggagctccag aaagctgtgg accaccgcaa agccatcatc ctctccatca  25800

atctctgcag ccctgagttc acccaggctg acagcaagga gagccgggac ctgcaggatc  25860

gcttgtcgca gatgaatggg cgctgggacc gagtgtgctc tctgctggag gagtggcggg  25920

gcctgctgca ggatgccctg atgcagtgcc agggtttcca tgaaatgagc catggtttgc  25980

ttcttatgct ggagaacatt gacagaagga aaaatgaaat tgtccctatt gattctaacc  26040

ttgatgcaga gatacttcag gaccatcaca aacagcttat gcaaataaag catgagctgt  26100

tggaatccca actcagagta gcctctttgc aagacatgtc ttgccaacta ctggtgaatg  26160

ctgaaggaac agactgttta gaagccaaag aaaaagtcca tgttattgga aatcggctca  26220

aacttctctt gaaggaggtc agtcgtcata tcaaggaact ggagaagtta ttagacgtgt  26280

caagtagtca gcaggatttg tcttcctggt cttctgctga tgaactggac acctcagggt  26340

ctgtgagtcc cacatcagga aggagcaccc caaacagaca gaaaacgcca cgaggcaagt  26400

gtagtctctc acagcctgga ccctctgtca gcagtccaca tagcaggtcc acaaaaggtg  26460

gctccgattc ctccctttct gagccagggc caggtcggtc cggccgcggc ttcctgttca  26520

gagtcctccg agcagctctt ccccttcagc ttctcctgct cctcctcatc gggcttgcct  26580

gccttgtacc aatgtcagag gaagactaca gctgtgccct ctccaacaac tttgcccggt  26640

cattccaccc catgctcaga tacacgaatg gccctcctcc actctgaact aagcagatgc  26700

catctgcaga agtgctggta gcataaggag gatcgggtca taagcaatcc caaactacca  26760

acaagaggac cttgatcttg gcgaaagccc tcggtgtggc agctttagcc ctcctccaga  26820

tcacatgtgt gcaaattatg gcttcagagg tggaagataa acagtgacgg gggaacaaac  26880

agacaacaag aaggtttgga agaaatctgg tttgagactc tgaaccttag cactaaggag  26940

attgagtaag gacctccaaa gttccccgga ctcatgaatt ctgggccctt ggcccattct  27000

gtgcacagcc aaggacttca gtagaccatc tgggcagctt tcccatggtg ctgctccaac  27060

catcagataa atgaccctcc caagcaccat gtcagtgtcg tacaatctac caaccaacca  27120

gtgctgaaga gattttagaa ccttgtaaca tacaattttt aagagcttat atggcagctt  27180

cctttttacc ttgttttcct ttggggcatg atgttttaac ctttgcttta gaagcacaag  27240

ctgtaaatct aaaaggcact tttttttaga ggtataaaga aaaactagat gtaataaata  27300

agatcatgga aggctttatg tgaaaaaagt tgaatgttat agtaaaaaaa aaaagatatt  27360

tatgtatgta cagtttgcta aagccaagtt ttgtttgtat tgatttcttt gcatttatta  27420

tagatattat aaaatagtt                                               27439


<210>  874
<211>  2310
<212>  DNA
<213>  Human

<400>  874
acttccgttt ttgctgggta ggcgacccgg acggagggcc ggcgaggtgc ggggtctggt     60

gatgcgagct gcgcctctcg gcaagatttc gcgctgccca tcccgggccc tttcatcagt    120

aatcggtagt ggatcactct gccaagcggc aggaagaatt aaggaaacga caaggagacg    180

ctcggctctc tcccgcttgg ctccttgcgg cctcctcttc ccttcgctcc ggcccggtga    240

aactgaactt ataatcgtca ctggattgta agtacccgag gcgaagagag ctcgctgagc    300

cctgattttt tgagtgtctt tgttccggga gagtttgtga gttgaaagta tctctgctgg    360

gctttctggg ccgaaaaccg ttccggggga gccgccattt gctttcctgt tccctagcta    420

gctagctagc tctctccgcg ttgtccggca gcggcaccta gaggttggga cttggcattg    480

catctgattt aatgaactta agtctgtgaa taagcctttg tgttaacgac tggtattcgg    540

tcacagcata tttagagaaa agacttggag cttaaataaa aactaaggca aaatagacgc    600

ttagctgctg atctacagag aacttcttgt aattaaaaga tttcaattca tagcaaactg    660

gtgttttaaa ctattgcagt agctggaact ttttagtgta accagcattt attggagaag    720

tgaatcacaa ggaaataaag atgagtaaaa gcaaagatga tgctcctcac gaactggaga    780

gccagtttat cttacgtctg cctccagaat atgcctctac tgtgagaagg gcagtacagt    840

ctggtcatgt caacctcaag gacagactga caattgagtt acatcctgat gggcgtcatg    900

gaatcgtcag agtggaccgt gttccattgg cctcaaaatt agtagacctg ccctgtgtta    960

tggaaagctt gaaaaccatt gataaaaaaa ctttttacaa gacagctgat atctgtcaga   1020

tgcttgtatc cacagttgat ggtgatctct atcctcctgt ggaggagcca gttgctagca   1080

ctgatcctaa agcaagcaag aaaaaggata aggacaaaga gaaaaagttt atctggaacc   1140

acggaattac tctgcctcta aagaatgtca ggaagagaag gttccggaag acagcaaaga   1200

agaaatatat tgaatctcca gatgttgaaa aagaagtgaa acgattgctg agtacagatg   1260

ctgaagctgt tagtactcgg tgggaaataa ttgccgaaga tgaaacaaag gaggcagaaa   1320

atcaaggcct ggatatctct tctccaggaa tgtctggtca caggcagggc catgactcat   1380

tagaacatga tgagcttcgg gagatattca atgacctcag cagcagcagt gaggatgaag   1440

atgagaccca gcatcaagat gaagaagata taaacatcat tgacacggag gaagatctgg   1500

agagacagct acaggacaag ctaaatgaat cagatgaaca gcaccaggaa aatgaaggaa   1560

ccaatcagct ggttatggga attcagaagc agattgacaa catgaaaggc aagctccaag   1620

agacccagga cagggcaaaa cgacaagagg atctcatcat gaaagtggaa aatctggctc   1680

tcaagaacag atttcaggct gtactggatg agctcaaaca aaaggaagac cgagaaaagg   1740

agcaactcag ctctttgcaa gaggagctag aatcactcct agagaagtaa aaagaactga   1800

tatttaattt cagtcttcag actggtcagc attagaaaat tcttggcttt attgtactgg   1860

gtattaagac cttgctcttc ctagtccttt taatgctgtg tgttctgtta agttctttca   1920

tttgtttgta attttgtttt tcagcaaatt tatattgttt tgctaggtgt tcatcctata   1980

agaagcagga ttgtataggc agaaaaatga ttgtaggaaa gttgcaggat tagcggaatg   2040

tatggttcaa ccttaattat agcttcattg caggacttta ctgtttctcc attttctaga   2100

agctgctgtt gctgctttgt gatgacgtga gatcaataag aagaacctag tctagagaca   2160

atgatgctag tttgcatatg ttttcctatg caataattgt tttcccagtt attcaaagca   2220

gctttctata tgtagagatg caaattatta agttgtttcc aatacaataa ataaaagcat   2280

ctgtttttca ctttaaaaaa aaaaaaaaaa                                    2310


<210>  875
<211>  1448
<212>  DNA
<213>  Human

<400>  875
gcctctccag ctgcgacaca gatggcgcgc gggctcttgg gttctgtagt tttctcgcga     60

tccaaaaggc tccgtgccca aagcaaatgc tggccgccaa cccaggcaag accccgatca    120

gccttctgca ggagtatggg accagaatag ggaagacgcc tgtgtacgac cttctcaaag    180

ccgagggcca agcccaccag cctaatttca ccttccgggt caccgttggc gacaccagct    240

gcactggtca gggccccagc aagaaggcag ccaagcacaa ggcagctgag gtggccctca    300

aacacctcaa aggggggagc atgctggagc cggccctgga ggacagcagt tctttttctc    360

ccctagactc ttcactgcct gaggacattc cggtttttac tgctgcagca gctgctaccc    420

cagttccatc tgtagtccta accaggagcc cccccatgga actgcagccc cctgtctccc    480

ctcagcagtc tgagtgcaac cccgttggtg ctctgcagga gctggtggtg cagaaaggct    540

ggcggttgcc ggagtacaca gtgacccagg agtctgggcc agcccaccgc aaagaattca    600

ccatgacctg tcgagtggag cgtttcattg agattgggag tggcacttcc aaaaaattgg    660

caaagcggaa tgcggcggcc aaaatgctgc ttcgagtgca cacggtgcct ctggatgccc    720

gggatggcaa tgaggtggag cctgatgatg accacttctc cattggtgtg ggctcccgcc    780

tggatggtct tcgaaaccgg ggcccaggtt gcacctggga ttctctacga aattcagtag    840

gagagaagat cctgtccctc cgcagttgct ccctgggctc cctgggtgcc ctgggccctg    900

cctgctgccg tgtcctcagt gagctctctg aggagcaggc ctttcacgtc agctacctgg    960

atattgagga gctgagcctg agtggactct gccagtgcct ggtggaactg tccacccagc   1020

cggccactgt gtgtcatggc tctgcaacca ccagggaggc agcccgtggt gaggctgccc   1080

gccgtgccct gcagtacctc aagatcatgg caggcagcaa gtgaagcccc agctggactc   1140

atggatgtgc accctttgct ccctgctctt tctgcctctg ggctcatgta tctgcgcagc   1200

tctggtaccc tctgtgggtg ccatctctac ctctgacaca gactgcctgc cttgaagctg   1260

agaaggcaca gggcaaggag ccaaggacca cagagcctca gccagcccag gatccgtcct   1320

cattttattg gtgatgatga atgggaatga aatcaggggg ctgtctacta gagcctggaa   1380

taaatatgct gctttgtgga tttttaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1440

aaaaaaaa                                                            1448


<210>  876
<211>  3877
<212>  DNA
<213>  Human

<400>  876
gaaagaggag ccggaagtgt ggcgcgcgag gtctaagggc gcgagggaag tggcgggcgg     60

ggactaaggc ggggcgtgca ggtagccggc cggccggggg tcgcgggtat ggccgaggcc    120

aggaagcggc gggagctact tcccctgatc taccaccatc tgctgcgggc tggctatgtg    180

cgtgcggcgc gggaagtgaa ggagcagagc ggccagaagt gtttcctggc tcagcccgta    240

acccttctgg acatctatac acactggcaa caaacctcag agcttggtcg gaagcggaag    300

gcagaggaag atgcggcact gcaagctaag aaaacccgtg tgtcagaccc catcagcacc    360

tcggagagct cggaagagga ggaagaagca gaagccgaaa ccgccaaagc caccccaaga    420

ctagcatcta ccaactcctc agtcctgggg gcggacttgc catcaagcat gaaagaaaaa    480

gccaaggcag agacagagaa agctggcaag actgggaatt ccatgccaca ccctgccact    540

gggaagacgg tggccaacct tctttctggg aagtctccca ggaagtcagc agagccctca    600

gcaaatacta cgttggtctc agaaactgag gaggagggca gcgtcccggc ctttggagct    660

gctgccaagc ctgggatggt gtcagcgggc caggccgaca gctccagcga ggacacctcc    720

agctccagtg atgagacaga cgtggagggg aaaccctcag taaaaccagc ccaggtcaaa    780

gcctcatcag tttctactaa ggagtctcca gcaagaaagg cggccccagc ccctgggaag    840

gtgggggatg tgacacccca ggtcaaagga ggggccctgc ccccagccaa gagggccaag    900

aagccagaag aggagtcaga gagtagtgag gagggatctg aaagtgagga ggaggcccct    960

gcagggacac gaagccaggt aaaggcctct gaaaaaattc tccaggtcag agctgcctca   1020

gcccctgcca aggggacccc tgggaaaggg gctaccccag caccccctgg gaaggcaggg   1080

gctgtagcct cccagaccaa ggcagggaag ccagaggagg actcagagag cagcagcgag   1140

gagtcatctg acagtgagga ggagacgcca gctgccaagg ccctgcttca ggcgaaggcc   1200

tcaggaaaaa cctctcaggt cggagctgcc tcagcccctg ccaaggagtc ccccaggaaa   1260

ggagctgccc cagcgccccc tgggaagaca gggcctgcag ttgccaaggc ccaggcgggg   1320

aagcgggagg aggactcgca gagcagcagc gaggaatcgg acagtgagga ggaggcgcct   1380

gctcaggcga agccttcagg gaaggccccc caggtcagag ccgcctcggc ccctgccaag   1440

gagtccccca ggaaaggggc tgccccagca cctcctagga aaacagggcc tgcagccgcc   1500

caggtccagg tggggaagca ggaggaggac tcaagaagca gcagcgagga gtcagacagt   1560

gacagagagg cactggcagc catgaatgca gctcaggtga agcccttggg gaaaagcccc   1620

caggtgaaac ctgcctctac catgggcatg gggcccttgg ggaaaggcgc cggcccagtg   1680

ccacccggga aggtggggcc tgcaaccccc tcagcccagg tggggaagtg ggaggaggac   1740

tcagagagca gtagtgagga gtcatcagac agcagtgatg gagaggtgcc cacagctgtg   1800

gccccggctc aggaaaagtc cttggggaac atcctccagg ccaaacccac ctccagtcct   1860

gccaaggggc cccctcagaa ggcagggcct gtagccgtcc aggtcaaggc tgaaaagccc   1920

atggacaact cggagagcag cgaggagtca tcggacagtg cggacagtga ggaggcacca   1980

gcagccatga ctgcagctca ggcaaaacca gctctgaaaa ttcctcagac caaggcctgc   2040

ccaaagaaaa ccaataccac tgcatctgcc aaggtcgccc ctgtgcgagt gggcacccaa   2100

gccccccgga aagcaggaac tgcgacttct ccagcaggct catccccagc tgtggctggg   2160

ggcacccaga gaccagcaga ggattcttca agcagtgagg aatcagatag tgaggaagag   2220

aagacaggtc ttgcagtaac cgtgggacag gcaaagtctg tggggaaagg cctccaggtg   2280

aaagcagcct cagtgcctgt caaggggtcc ttggggcaag ggactgctcc agtactccct   2340

gggaagacgg ggcctacagt cacccaggtg aaagctgaaa agcaggaaga ctctgagagc   2400

agtgaggagg aatcagacag tgaggaagca gctgcatctc cagcacaggt gaaaacctca   2460

gtaaagaaaa cccaggccaa agccaaccca gctgccgcca gagcaccttc agcaaaaggg   2520

acaatttcag cccctggaaa agttgtcact gcagctgctc aagccaagca gaggtctcca   2580

tccaaggtga agccaccagt gagaaacccc cagaacagta ccgtcttggc gaggggccca   2640

gcatctgtgc catctgtggg gaaggccgtg gctacagcag ctcaggccca gacagggcca   2700

gaggaggact cagggagcag tgaggaggag tcagacagtg aggaggaggc ggagacgctg   2760

gctcaggtga agccttcagg gaagacccac cagatcagag ctgccttggc tcctgccaag   2820

gagtccccca ggaaaggggc tgccccaaca cctcctggga agacagggcc ttcggctgcc   2880

caggcaggga agcaggatga ctcagggagc agcagcgagg aatcagacag tgatggggag   2940

gcaccggcag ctgtgacctc tgcccaggac caggagtctt cttgaatccc atgagctctg   3000

cccaggaccc tctctcaagc acctgtggca taccttcatg tgctccactg cacccagagc   3060

ttaagccaca gtcctgctca ggctacacct ccaagggtgg gaccaggccc accttatctt   3120

cctgtactcc agaggcccaa gtcagccatg ctggtgtggt ccaagcttct gtgtgaaccc   3180

tggcccttcc atcagacagc attacccttt gtcctcctct agccccaagc tcccagaagc   3240

ttctgccagg cacctcagag caccagctcc cctgtcccag ggcctaacca cagatcctgg   3300

agttctgcaa cctccagacc agagcggtct catgaaccac ctccccttga atatcacata   3360

ccacattgtt atcaattcat cagtaaggtc agatgctgtt tgcacacctc cagcaatagg   3420

gtgctcactg cctctcactt tccaatggca cagattacaa aagtaaagaa caaccaccac   3480

caacatcggt aactccctgt attctcattt ttctgtttaa tctccacaac agccctatga   3540

gggtggctcc ctttgttgtt tgcattttaa ggaactggga gtgaggctca gagaagttga   3600

gggacctgtc ccagcatcac atggctgatg acaagtggac agacctggtg tttgagcaca   3660

ggccattcac attctgaccc gttgcctggt gctgccccga cactctcctc tcctgggctt   3720

gggcattgcc ctctggctct gtgtggagcc tttacgaggc cacctgcctc tctgagggat   3780

ctaaacaact gggagggagg ggaccgctcc ccctttctct gtgggggtgg actaacacaa   3840

ttaaaatgaa catcctgctt aaaaaaaaaa aaaaaaa                            3877


<210>  877
<211>  2444
<212>  DNA
<213>  Human

<400>  877
attactgaca caaacgctcc ctcagggcgt ccccgtctgg actacaggag aaagtttggg     60

aggcaggttc aacttttcaa cttggcgggg aattcctctc cctcttacac agtttgcagc    120

gcgggggcgg cggggtgaca gtccccgtgc atgaatcagc cacccctcag gctccgcccc    180

ggcgggggtc ggccggacgc tcgccccgca taaagcgggc acccgggccg cctggagcag    240

aaagccgcgc acctcctccc gccaggcgct ttctcggacg ccttgcccag cgggccgccc    300

gaccccctgc accatggacc ccgctcgccc cctggggctg tcgattctgc tgcttttcct    360

gacggaggct gcactgggcg atgctgctca ggagccaaca ggaaataacg cggagatctg    420

tctcctgccc ctagactacg gaccctgccg ggccctactt ctccgttact actacgacag    480

gtacacgcag agctgccgcc agttcctgta cgggggctgc gagggcaacg ccaacaattt    540

ctacacctgg gaggcttgcg acgatgcttg ctggaggata gaaaaagttc ccaaagtttg    600

ccggctgcaa gtgagtgtgg acgaccagtg tgaggggtcc acagaaaagt atttctttaa    660

tctaagttcc atgacatgtg aaaaattctt ttccggtggg tgtcaccgga accggattga    720

gaacaggttt ccagatgaag ctacttgtat gggcttctgc gcaccaaaga aaattccatc    780

attttgctac agtccaaaag atgagggact gtgctctgcc aatgtgactc gctattattt    840

taatccaaga tacagaacct gtgatgcttt cacctatact ggctgtggag ggaatgacaa    900

taactttgtt agcagggagg attgcaaacg tgcatgtgca aaagctttga aaaagaaaaa    960

gaagatgcca aagcttcgct ttgccagtag aatccggaaa attcggaaga agcaatttta   1020

aacattctta atatgtcatc ttgtttgtct ttatggctta tttgccttta tggttgtatc   1080

tgaagaataa tatgacagca tgaggaaaca aatcattggt gatttattca ccagttttta   1140

ttaatacaag tcacttttta aaaaatttgg atttttttat atataactag ctgctattca   1200

aatgtgagtc taccattttt aatttatggt tcaactgttt gtgagactga attcttgcaa   1260

tgcataagat ataaaagcaa atatgactca ctcatttctt ggggtcgtat tcctgatttc   1320

agaagaggat cataactgaa acaacataag acaatataat catgtgcttt taacatattt   1380

gagaataaaa aggactagca aataaaactc attttgcatt taaaagttgg attatatttt   1440

agtcccaaga agacaaagtc gcagattaac aacactttaa aaatattact cccattttat   1500

tgtgttagat tgcagtacaa tgaatgaata aggggattta tttaaaagat cttaactttc   1560

ttgactgatt taaaaagcta atcaatttat taaagccaga aatgttctcc tctgggaaag   1620

caatttctat ctatttatct accaatcccc actcacatgt atatgtttgt gtttacatag   1680

agatagatgg ttttaagggt tttcctattg ttaaattatt tcctaagaca ttgtgggttg   1740

gagaccacta aacttataaa aaaccaagga aagtaaagtt tttcaaatgt ttatactgtt   1800

taaggtgttt atttatataa accatgcatg agaaaccatg cataaattta ataatttaaa   1860

tttcaccagt aaattatcat tgattaaata tggtcatacc aatgaaatag gttttttctt   1920

tctctgtaat aaaacaattt ttctaaattc ttatgttttc atagcaagat taacatattt   1980

aattacaaat taaatatgca aaatgacaaa tgcgtttacc ttttgcttga acaatctttc   2040

atttaaaaat ttatcccagt tattttgaca aataggtata tgcctgagaa ctttgaatga   2100

tgctgaaagc tagaagcaaa ccaggtactc ttcagtcagg gactggttga agattttatg   2160

gatgaggagt tagcaaaata tctatatatg catatcttct gactcccagg atacataaga   2220

aacacagggc ctagaacagt atgaataaac acacatatac acaaacatca cagaagatac   2280

taaagatatt aaaaatgttt acctatagag gtttggagag aacagagggg tggacagttg   2340

tggagataat atttgtgtaa atataactgt gatatagttt ttatcttgga ccatgtaaat   2400

atttgacata attaataatc aaaattaaat aaaaaagaaa aagc                    2444


<210>  878
<211>  1753
<212>  DNA
<213>  Human

<400>  878
agacggaagt gcgggcggag gatccccagc cgggtcccaa gcctgtgcct gagcctgagc     60

ctgagcctga gcccgagccg ggagccggtc gcgggggctc cgggctgtgg gaccgctggg    120

cccccagcga tggcgaccct gtggggaggc cttcttcggc ttggctcctt gctcagcctg    180

tcgtgcctgg cgctttccgt gctgctgctg gcgcagctgt cagacgccgc caagaatttc    240

gaggatgtca gatgtaaatg tatctgccct ccctataaag aaaattctgg gcatatttat    300

aataagaaca tatctcagaa agattgtgat tgccttcatg ttgtggagcc catgcctgtg    360

cgggggcctg atgtagaagc atactgtcta cgctgtgaat gcaaatatga agaaagaagc    420

tctgtcacaa tcaaggttac cattataatt tatctctcca ttttgggcct tctacttctg    480

tacatggtat atcttactct ggttgagccc atactgaaga ggcgcctctt tggacatgca    540

cagttgatac agagtgatga tgatattggg gatcaccagc cttttgcaaa tgcacacgat    600

gtgctagccc gctcccgcag tcgagccaac gtgctgaaca aggtagaata tgcacagcag    660

cgctggaagc ttcaagtcca agagcagcga aagtctgtct ttgaccggca tgttgtcctc    720

agctaattgg gaattgaatt caaggtgact agaaagaaac aggcagacaa ctggaaagaa    780

ctgactgggt tttgctgggt ttcattttaa taccttgttg atttcaccaa ctgttgctgg    840

aagattcaaa actggaagca aaaacttgct tgattttttt ttcttgttaa cgtaataata    900

gagacatttt taaaagcaca cagctcaaag tcagccaata agtcttttcc tatttgtgac    960

ttttactaat aaaaataaat ctgcctgtaa attatcttga agtcctttac ctggaacaag   1020

cactctcttt ttcaccacat agttttaact tgactttcaa gataattttc agggtttttg   1080

ttgttgttgt tttttgtttg tttgttttgg tgggagaggg gagggatgcc tgggaagtgg   1140

ttaacaactt ttttcaagtc actttactaa acaaactttt gtaaatagac cttaccttct   1200

attttcgagt ttcatttata ttttgcagtg tagccagcct catcaaagag ctgacttact   1260

catttgactt ttgcactgac tgtattatct gggtatctgc tgtgtctgca cttcatggta   1320

aacgggatct aaaatgcctg gtggcttttc acaaaaagca gattttcttc atgtactgtg   1380

atgtctgatg caatgcatcc tagaacaaac tggccatttg ctagtttact ctaaagacta   1440

aacatagtct tggtgtgtgt ggtcttactc atcttctagt acctttaagg acaaatccta   1500

aggacttgga cacttgcaat aaagaaattt tattttaaac ccaagcctcc ctggattgat   1560

aatatataca catttgtcag catttccggt cgtggtgaga ggcagctgtt tgagctccaa   1620

tgtgtgcagc tttgaactag ggctggggtt gtgggtgcct cttctgaaag gtctaaccat   1680

tattggataa ctggcttttt tcttcctctg tcctctttgg aatgtaacaa taaaaataat   1740

ttttgaaaca tcc                                                      1753


<210>  879
<211>  5593
<212>  DNA
<213>  Human

<400>  879
tggagggggg aggtttttgt tgaggagagc gcggccggag agcagagctc cgggacccag     60

gtgaccggga aagcaggcag ccccagcggc gggagcagcc ggcagcagcc caggcccggg    120

gactggggtg ggggtgggag gggggctgag gggaggacct gaaggggggc ggcagggcaa    180

aagggacccc tggagccctg ccgccatcag agatcaagca tctggcatca gggatcttcg    240

gacccagcag aaggatccgc cacaggggag gtgtcctccc agggaagcca acgagagatt    300

cacctgcccc acatcaggag tgggcccccc ttactgacgc tgctggcaac catagcaggc    360

cccttaaccc ctcagtctcc tccccatcac cctcctcagg ccctttcccc gcctccagct    420

ctcatctcaa ctcccagttc ccagccctct aagccctagc acccccggct accacctaac    480

cctccaggtc ttggccatac tcacccccat cctgggacat ttgccagatc tctgggaggg    540

agatcgtttg tttaggcgat gccccctggt ggcatgacag cgtctgccta gacccctgac    600

ccctagcact caactccctg ggcctccttt gtgtgaagag ccgcccctct gcttagcagc    660

gtggttgggg gccaaaggga aagccagccc cagctgggcc cccgggcccc accacttatc    720

tccttgctgg gcagctcccc ttggcctttg ggcctctccc tgctcccctc ggcccctcct    780

cctgggccgc ctcaatgaag gagccggatg ccatcaagct gtttgtgggg cagatcccga    840

ggcatctgga ggagaaggac ctgaagccca tcttcgaaca gtttggtcgg atctttgagc    900

tgactgtcat caaggacaag tacaccgggc tgcacaaggg atgtgccttc ctgacatact    960

gtgcccggga ttcagccctg aaggcccaga gcgccctgca cgaacagaag acgcttccag   1020

ggatgaacag gccgatccag gtcaagccag ccgacagcga gagccgagga gaagaccgga   1080

agctctttgt ggggatgcta gggaagcagc agacagatga ggacgtccgg aagatgtttg   1140

agcccttcgg gaccatcgac gagtgcactg tgctccgggg gccagatggc accagcaaag   1200

gctgcgcctt cgtgaagttc cagacccacg ctgaggccca ggcggccatc aacacccttc   1260

acagcagccg gaccctgcca ggtgcctcgt ccagcctggt ggtgaagttt gctgacactg   1320

agaaggagcg aggtctccgc cgcatgcagc aggtggccac ccagttgggc atgttcagcc   1380

ccatcgccct ccagtttgga gcctacagcg cctacaccca ggccctgatg cagcagcagg   1440

cggccctggt agcggctcac agtgcctacc tcagccccat ggccaccatg gctgccgtgc   1500

agatgcagca catggctgcc atcaatgcca atggcctcat cgccaccccc atcaccccat   1560

cctcaggaac cagcacccct cctgccatcg ctgccacgcc tgtctctgcc attccggctg   1620

ccctgggcgt caacggctac agcccggtgc ccacccagcc cactgggcag cctgcccctg   1680

atgctctgta tcccaacggg gttcacccct acccagccca gagccccgcg gcccccgtgg   1740

accccctgca gcaggcctac gcggggatgc agcactacac agcagcctac ccagcagcct   1800

acagcctggt tgcacctgcg ttcccgcagc ctccagccct ggtcgcccag cagcccccac   1860

caccacctca acagcagcag cagcagcagc agcagcaaca gcagcagcag caaagagaag   1920

gccctgatgg ctgcaacatc ttcatctacc acctgcccca ggagttcact gactcagaga   1980

tcctccagat gtttgtcccc tttggccacg tcatctcagc caaagtcttt gttgaccgag   2040

ccaccaatca aagcaaatgt tttggctttg tgagtttcga caatccggcc agtgcccagg   2100

ctgccatcca ggccatgaat ggcttccaga tcggcatgaa gcgcctcaaa gtccagctaa   2160

agcggcctaa ggatgccaac cggccctact gagggccccc aggtctggag atcccagagg   2220

aaggggcgcc tcacaccctc ttcccacgac tggccccggc cctctccgca cacctgccct   2280

gggccttgac tgggttctgg ggcaaacgct gcttcgtggc ccccgggggc acaagacacc   2340

ggcccctccc acccccctgc ctctctgaag ggccatggct atgcttccct ggctccaagg   2400

gcccatttcc tcctagatgc ccttttggcc tttgtgaggg agcgaggaac aggctcgaag   2460

gctccggggt atctgccttc tgctgggctc ctgtgacagg ccttctgtac ccagcgtttg   2520

tacttgcctc ccccaacagt gggcctgttc tacccgtgca ggccccagga gagccgcagg   2580

ggcctgccac acactcccag ctcaccctca ccccagcctc ttccccacat taggggtttc   2640

ttggaagctg gctctcactc ccctccaccc tcagctagag gtaggatatc cctgattcct   2700

gggctcccag ccttaaaact cactgcctcc cccaagggcc ccctctaagg agggtgtggg   2760

ggagccctga gggctgcctc tctgccagtc agccacagag accctcctcc tttcacgagg   2820

aaaagacctt cccctgaacc cctaaaaatg tttacagtct ctgctggttc cctctgtgta   2880

aataccacta ccacccgtgc gttatccagc ccgcccggcc tggcccggac gctgccatct   2940

ctctttctgg gagtttagac aatgttgccc ttggattttt ttctctctct taatttctcc   3000

ctttgctttg gggggtaatt gggtattggg aggaggggtg tggggagggg tcaaggggtt   3060

tattacctga tcattttctt taggaagagg ttttagggaa aagaaaatgg ggtgggggtg   3120

ggggtggtaa ggggagaccg gggagtcagt ttcagacagt tctctatgct taacttattt   3180

atttattgca ttttactttt aaagagttgg tcttttctgt ctaaataaag aaaaaagttt   3240

aaaagcatca aataagagtc ttggaaggtt gagggtaggg gattgttccc tacccacact   3300

gggaaggggg agggaggtag agaatgaggt ttgagagaga aaatcccatc agggaaggcc   3360

gggcccttgc ttttgagcag catccaggcc ttgttcatgg cttcatgatc ctgtccttca   3420

gcccttcttt ggggcttaat tctggaatgt cctgcagagt tcggcacaag gagatctccc   3480

ctgtcggggg ctctcccctg tatccagctc tgtccctctg aaggctgagg acttgcagtc   3540

tcacatctgg acctccattt ctgcacagag gccagtgtgg atactgggag ccagttgtga   3600

caccaccatt tactaaccac tgctccatat gtgattctgt tccaagtcct tattgtgcat   3660

ttcctcattt tacctcctaa caaccttgtg aggcaggcta tagtttattt attttactta   3720

tttactttga aacagggtct cactctgtca ctcaagctgg agtgtgatgg tgagatcata   3780

gctcactgca accttgaact cctggttcag gggatcctcc tgtctcagcc tcccaagtag   3840

ttaggactat aagcggctgc accaccacgc ccagctcatt tttaaaaatg gtgttttttt   3900

ttgtagacag ggtcttgcta tgttgcccag gctggtctcg aacccctggg ctcaagcaaa   3960

cctcctgcct tggcctcccg aagtgctcag attacaggca tgagccacca cgcccagcct   4020

aggtaggata taattttata gatgggaaaa ggaggcttgg aaggttaact aacttccctg   4080

gagtcacaaa gccagtaagg catggctgta ggagttgaac ccagtttgtc agattccaaa   4140

gcccatgatg ttctcttctt acctgttctt tgacctgagg caaagatccc aagaagtagc   4200

aagcaggctt aggagtgagt ccttcaggta gagggtggac tgcataagcc ctaagtccct   4260

ccacttccta gattcttctc tgtgagctgc tttagggcag gctcaggatc acacaggtgt   4320

cttctttgac ttcatagaac atgtgcttct aggctgctac cccaccctct gtcttcatca   4380

ttagtaagca gcaccactag gtacctactc aagccaaaac ttggattaca ccctttctct   4440

catgtctcct ccccaatcca actgcaaagc cctaccaagt ctacctctaa agtattcagc   4500

tgatttactt actcatgtct ctgcatctcc acagccatca acactgtcca cgtcacattg   4560

ctctcatctg tctccatgtt tcttttcctg ctctcctaca atttgttctc ccaagaagcc   4620

aagagtcatc ttttaaaagt taattcacca acatttacta cccagtctgc tttgtccagc   4680

actgtatcct ggtcacccta aacagtgccc caaatattag acattgctta gtaaataaga   4740

aatgactgtt ggacatctat actggacttc ccatccatat ctacatcatc atagggccaa   4800

tgctaaaact ttctcccata aagtcctgac tcatatattt ctattttcta gtcacataga   4860

cagaaaacct caagagtttt tagtactttc gcataaactc aatggtatta aatcatttaa   4920

gatttcactt ccacaaactt tctcatatca tttccctctt ttcaattatc actgcctaca   4980

cttattaact gagtaatcat agcaatttcc taattggtcc ttctgtctat gttctgaagc   5040

atcaatcttt ctaaactgca gctaataaaa aacaaaactt ctctgctgct gttttttgtt   5100

gtttttcata gaacacctca gcctggcatt caaggctctt cgaagcctta ctttccactt   5160

cattcctaca catacccaaa tagaactatt cattgttctc taggcaagtt tggtcccttt   5220

tctcccatgt cttttcattc ccagttacta cagtgtctgg cacataacgg ctcaataaat   5280

gtttgttgaa tgccttcttg ttgaaatcct tctcacacta aaacagttca ccttaaacac   5340

tactttcttc atgaaaatct taacggccct catccacagg tctttctcct tccttttcta   5400

gtccttatgg cacttaaacc tttcactgct gtgtatcatg gccatgcgta agtgtctcat   5460

tcttctgtga gcctgtaagc tggcagaaat gtttctttct ttgcttttgt gtctgttgca   5520

gtatctcaaa caatctcccc accccacccc caacagcaga tacctaataa atgtttgact   5580

ttaaccactg taa                                                      5593


<210>  880
<211>  2989
<212>  DNA
<213>  Human

<400>  880
ggcgcgcggg cgagcggttg tgcttgtgct tgtggcgcgt ggtgcgggtt tcggcggcgg     60

ctgaggaaga agcgcgggcg gcgccttcgg gaggcgagca ggcagcagtt ggccgtgccg    120

tagcagcgtc ccgcgcgcgg cgggcagcgg cccaggaggc gcgtggcggc gctcggcctc    180

gcggcggcgg cggcggcagc ggcccagcag ttggcggcga gcgcgtctgc gcctgcgcgg    240

cgggccccgc gcccctcctc cccccctggg cgcccccggc ggcgtgtgaa tggcggcctc    300

cgcggcggca gcctcggcag cagcggcctc ggccgcctct ggcagcccgg gcccgggcga    360

gggctccgct ggcggcgaaa agcgctccac cgccccttcg gccgcagcct cggcctctgc    420

ctcagccgcg gcgtcgtcgc ccgcgggggg cggcgccgag gcgctggagc tgctggagca    480

ctgcggcgtg tgcagagagc gcctgcgacc cgagagggag ccccgcctgc tgccctgttt    540

gcactcggcc tgtagtgcct gcttagggcc cgcggccccc gccgccgcca acagctcggg    600

ggacggcggg gcggcgggcg acggcaccgt ggtggactgt cccgtgtgca agcaacagtg    660

cttctccaaa gacatcgtgg agaattattt catgcgtgat agtggcagca aggctgccac    720

cgacgcccag gatgcgaacc agtgctgcac tagctgtgag gataatgccc cagccaccag    780

ctactgtgtg gagtgctcgg agcctctgtg tgagacctgt gtagaggcgc accagcgggt    840

gaagtacacc aaggaccata ctgtgcgctc tactgggcca gccaagtctc gggatggtga    900

acgtactgtc tattgcaacg tacacaagca tgaacccctt gtgctgtttt gtgagagctg    960

tgatactctc acctgccgag actgccagct caatgcccac aaggaccacc agtaccagtt   1020

cttagaggat gcagtgagga accagcgcaa gctcctggcc tcactggtga agcgccttgg   1080

ggacaaacat gcaacattgc agaagagcac caaggaggtt cgcagctcaa tccgccaggt   1140

gtctgacgta cagaagcgtg tgcaagtgga tgtcaagatg gccatcctgc agatcatgaa   1200

ggagctgaat aagcggggcc gtgtgctggt caatgatgcc cagaaggtga ctgaggggca   1260

gcaggagcgc ctggagcggc agcactggac catgaccaag atccagaagc accaggagca   1320

cattctgcgc tttgcctctt gggctctgga gagtgacaac aacacagccc ttttgctttc   1380

taagaagttg atctacttcc agctgcaccg ggccctcaag atgattgtgg atcccgtgga   1440

gccacatggc gagatgaagt ttcagtggga cctcaatgcc tggaccaaga gtgccgaggc   1500

ctttggcaag attgtggcag agcgtcctgg cactaactca acaggccctg cacccatggc   1560

ccctccaaga gccccagggc ccctgagcaa gcagggctct ggcagcagcc agcccatgga   1620

ggtgcaggaa ggctatggct ttgggtcagg agatgatccc tactcaagtg cagagcccca   1680

tgtgtcaggt gtgaaacggt cccgctcagg tgagggcgag gtgagcggcc ttatgcgcaa   1740

ggtgccacga gtgagccttg aacgcctgga cctggacctc acagctgaca gccagccacc   1800

cgtcttcaag gtcttcccag gcagtaccac tgaggactac aaccttattg ttattgaacg   1860

tggcgctgcc gctgcagcta ccggccagcc agggactgcg cctgcaggaa cccctggtgc   1920

cccacccctg gctggcatgg ccattgtcaa ggaggaggag acggaggctg ccattggagc   1980

ccctcctact gccactgagg gccctgagac caaacctgtg cttatggctc ttgcggaggg   2040

tcctggtgct gagggtcccc gcctggcctc acctagtggc agcaccagct cagggctgga   2100

ggtggtggct cctgagggta cctcagcccc aggtggtggc ccgggaaccc tggatgacag   2160

tgccaccatt tgccgtgtct gccagaagcc aggcgatctg gttatgtgca accagtgtga   2220

gttttgtttc cacctggact gtcacctgcc ggccctgcag gatgtaccag gggaggagtg   2280

gagctgctca ctctgccatg tgctccctga cctgaaggag gaggatggca gcctcagcct   2340

ggatggtgca gacagcactg gcgtggtggc caagctctca ccagccaacc agcggaaatg   2400

tgagcgtgta ctgctggccc tattctgtca cgaaccctgc cgccccctgc atcagctggc   2460

taccgactcc accttctccc tggaccagcc cggtggcacc ctggatctga ccctgatccg   2520

tgcccgcctc caggagaagt tgtcacctcc ctacagctcc ccacaggagt ttgcccagga   2580

tgtgggccgc atgttcaagc aattcaacaa gttaactgag gacaaggcag acgtgcagtc   2640

catcatcggc ctgcagcgct tcttcgagac gcgcatgaac gaggccttcg gtgacaccaa   2700

gttctctgct gtgctggtgg agcccccgcc gatgagcctg cctggtgctg gcctgagttc   2760

ccaggagctg tctggtggcc ctggtgatgg cccctgaggc tggagccccc atggccagcc   2820

cagcctggct ctgttctctg tcctgtcacc ccatccccac tcccctggtg gcctgactcc   2880

cactccctgg tggccccatc ccccagttcc tcacgatatg gtttttactt ctgtggattt   2940

aataaaaact tcaccagtta aaaaaaaaaa aaaaaaaaaa aaaaaaaaa               2989


<210>  881
<211>  10244
<212>  DNA
<213>  Human

<400>  881
gcagccatga gcggcagcag cggcggagcc gccgcccccg ccgcgtcctc cggccccgcc     60

gcggcggcca gcgcggctgg ctcgggctgc gggggcggtg ccggcgaggg ggcagaggag    120

gcggccaagg acctggccga catcgcggcc ttcttccgat ccgggtttcg aaaaaacgat    180

gaaatgaaag ctatggatgt tttaccaatt ttgaaggaaa aagttgcata cctttcaggt    240

gggagagata aacgtggagg tcccatttta acgtttccgg cccgcagcaa tcatgacaga    300

atacgacagg aggatctcag gagactcatt tcctatctag cctgtattcc cagcgaggag    360

gtctgcaagc gtggcttcac ggtgatcgtg gacatgcgtg ggtccaagtg ggactccatc    420

aagccccttc tgaagatcct gcaggagtcc ttcccctgct gcatccatgt ggccctgatc    480

atcaagccag acaacttctg gcagaaacag aggactaatt ttggcagttc taaatttgaa    540

tttgagacaa atatggtctc tttagaaggc cttaccaaag tagttgatcc ttctcagcta    600

actcctgagt ttgatggctg cctggaatac aaccacgaag aatggattga aatcagagtt    660

gcttttgaag actacattag caatgccacc cacatgctgt ctcggctgga ggaacttcag    720

gacatcctag ctaagaagga gctgcctcag gatttagagg gggctcggaa tatgatcgag    780

gaacattctc agctgaagaa gaaggtgatt aaggccccca tcgaggacct ggatttggag    840

ggacagaagc tgcttcagag gatacagagc agtgaaagct ttcccaaaaa gaactcaggc    900

tcaggcaatg cggacctgca gaacctcttg cccaaggtgt ccaccatgct ggaccggctg    960

cactcgacac ggcagcatct gcaccagatg tggcatgtga ggaagctgaa gctggaccag   1020

tgcttccagc tgaggctgtt tgaacaggat gctgagaaga tgtttgactg gatcacacac   1080

aacaaaggcc tgtttctaaa cagctacaca gagattggga ccagccaccc tcatgccatg   1140

gagcttcaga cgcagcacaa tcactttgcc atgaactgta tgaacgtgta tgtaaatata   1200

aaccgcatca tgtcggtggc caatcgtctg gtggagtctg gccactatgc ctcgcagcag   1260

atcaggcaga tcgcgagtca gctggagcag gagtggaagg cgtttgcggc agccctggat   1320

gagcggagca ccttgctgga catgtcctcc attttccacc agaaggccga aaagtatatg   1380

agcaacgtgg attcatggtg taaagcttgc ggtgaggtag accttccctc agagctgcag   1440

gacctagaag atgccattca tcaccaccag ggaatatatg aacatatcac tcttgcttat   1500

tctgaggtca gccaagatgg gaagtcgctc cttgacaagc tccagcggcc cttgactccc   1560

ggcagctccg attccctgac agcctctgcc aactactcca aggccgtgca ccatgtcctg   1620

gatgtcatcc acgaggtgct gcaccaccag cggcagctgg agaacatctg gcaacaccgc   1680

aaggtccggc tgcatcagag gctgcagctg tgtgttttcc agcaggacgt tcagcaggtg   1740

ctagactgga tcgagaacca cggagaagca tttctgagca aacatacagg tgtggggaaa   1800

tctcttcatc gggccagagc attgcagaaa cgtcatgaag attttgaaga agtggcacag   1860

aacacataca ccaatgcgga taaattactg gaagcagcag aacagctggc tcagactggg   1920

gaatgtgacc ccgaagagat ttatcaggct gcccatcagc tggaagaccg gattcaagat   1980

ttcgttcggc gtgttgagca gcgaaagatc ctactggaca tgtcagtgtc ctttcacacc   2040

catgtgaaag agctgtggac gtggctggag gagctgcaga aggagctgct ggacgacgtg   2100

tatgccgagt cggtggaggc cgtgcaggac ctcatcaagc gctttggcca gcagcagcag   2160

accaccctgc aggtgactgt caacgtgatc aaggaagggg aggacctcat ccagcagctc   2220

agggactctg ccatctccag taacaagacc ccccacaaca gctccatcaa ccacattgag   2280

acggtgctgc agcagctgga cgaggcgcag tcgcagatgg aggagctctt ccaggagcgc   2340

aagatcaagc tggagctctt cctgcagctg cgcatcttcg agagggacgc catcgacatt   2400

atctcagacc tcgagtcttg gaatgatgag ctttctcagc aaatgaatga cttcgacaca   2460

gaagatctca cgattgcaga gcagcgcctc cagcaccatg cagacaaagc cttgaccatg   2520

aacaacttga cttttgacgt catccaccaa gggcaagatc ttctgcagta tgtcaatgag   2580

gtccaggcct ctggtgtgga gctgctgtgt gatagagatg tagacatggc aactcgggtc   2640

caggacctgc tggagtttct tcatgaaaaa cagcaggaat tggatttagc cgcagagcag   2700

catcggaaac acctggagca gtgcgtgcag ctgcgccacc tgcaggcaga agtgaaacag   2760

gtgctgggtt ggatccgcaa cggagagtcc atgttaaatg ccggacttat cacagccagc   2820

tcgttacaag aggcagagca gctccagcga gagcacgagc agttccagca tgccattgag   2880

aaaacacatc agagcgcgct gcaggtgcag cagaaggcag aagccatgct acaggccaac   2940

cactacgaca tggacatgat ccgggactgc gccgagaagg tggcgtctca ctggcaacag   3000

ctcatgctca agatggaaga tcgcctcaag ctcgtcaacg cctctgtcgc tttctacaaa   3060

acctcagagc aggtctgcag cgtcctcgag agcctggaac aggagtacaa gagagaagaa   3120

gactggtgtg gcggggcgga taagctgggc ccaaactctg agacggacca cgtgacgccc   3180

atgatcagca agcacctgga gcagaaggag gcattcctga aggcttgcac ccttgctcgg   3240

aggaatgcag acgtcttcct gaaatacctg cacaggaaca gcgtgaacat gccaggaatg   3300

gtgacgcaca tcaaagctcc tgaacagcaa gtgaaaaata tcttgaatga actcttccaa   3360

cgggagaaca gggtattgca ttactggacc atgaggaaga gacggctgga ccagtgtcag   3420

cagtacgtgg tctttgagag gagtgccaag caggctttgg aatggatcca tgacaatggc   3480

gagttctacc tttccacaca cacctccacg ggctccagta tacagcacac ccaggagctc   3540

ctgaaagagc acgaggagtt ccagataact gcaaagcaaa ccaaagagag agtgaagcta   3600

ttgatacagc tggctgatgg cttttgtgaa aaagggcatg cccatgcggc agagataaaa   3660

aaatgtgtta ctgctgtgga taagaggtac agagatttct ctctgcggat ggagaagtac   3720

aggacctctt tggaaaaagc cctggggatt tcttcagatt ccaacaaatc gagtaaaagt   3780

ctccagctag atatcattcc agccagtatc cctggctcag aggtgaaact tcgagatgct   3840

gctcatgaac ttaatgaaga gaagcggaaa tctgcccgca ggaaagagtt cataatggct   3900

gagctcattc aaactgaaaa ggcttatgta agagacctcc gggaatgtat ggatacgtac   3960

ctgtgggaaa tgaccagtgg cgtggaagag attccacctg gcattgtaaa caaagaactc   4020

atcatcttcg gaaacatgca agaaatctac gaatttcata ataacatatt cctaaaggag   4080

ctggaaaaat atgaacagtt gccagaggat gttggacatt gttttgttac ttgggcagac   4140

aagtttcaga tgtatgtcac atattgcaaa aataagcctg attctactca gctgatattg   4200

gaacatgcag ggtcctattt tgacgagata cagcagcgac atggattagc caattccatt   4260

tcttcctacc ttattaaacc agttcagcga ataacgaagt atcagctcct tttaaaagag   4320

ctgctgacgt gctgtgagga aggaaaggga gagattaaag atggcctgga ggtgatgctc   4380

agcgtgccga agcgagccaa tgatgccatg cacctcagca tgctggaagg gtttgatgaa   4440

aacattgagt ctcagggaga actcatccta caggaatcct tccaagtgtg ggacccaaaa   4500

accttaattc gaaagggtcg agaacggcat ctcttccttt ttgaaatgtc cttagtattt   4560

agtaaagaag tgaaagattc cagtgggaga agcaagtacc tttataaaag caaattgttt   4620

acctcagagt tgggtgtcac agaacatgtt gaaggagacc cttgcaaatt tgcactgtgg   4680

gtggggagaa caccaacttc agataataaa attgtcctta aggcttccag catagagaac   4740

aagcaggact ggataaagca tatccgcgaa gtcatccagg agcggacgat ccacctgaag   4800

ggagccctga aggagcccat tcacatccct aagaccgctc ccgccacaag acagaaggga   4860

aggagggatg gagaggatct ggacagccaa ggagacggca gcagccagcc tgatacgatt   4920

tccatcgcct cacggacgtc tcagaacacg ctggacagcg ataagctctc tggtggctgt   4980

gagctgacag tggtgatcca tgacttcacc gcttgcaaca gcaacgagct gaccatccga   5040

cggggccaga ccgtggaagt tctggagcgg ccgcatgaca agcctgactg gtgtctggtg   5100

cggacaactg accgctcccc agcggcagaa ggcctggtcc cctgtggttc actgtgcatc   5160

gcccactcca gaagtagcat ggaaatggag ggcatcttca accacaaaga ctcgctctcc   5220

gtctccagca atgacgccag tccacccgca tccgtggctt ccctccagcc ccacatgatc   5280

ggggcccaga gctcgccggg ccccaagcgg ccgggcaaca ccctgcgcaa gtggctcacc   5340

agccccgtgc ggcggctcag cagcggcaag gccgacgggc acgtgaagaa gctggcgcac   5400

aagcacaaga agagccgcga ggtccgcaag agcgccgacg ccggctcgca gaaggactcc   5460

gacgacagtg cggccacccc gcaggacgag acggtcgagg agagaggccg gaacgagggc   5520

ctgagcagcg gtactctctc caaatcctcc tcctcgggga tgcagagctg tggagaagag   5580

gaaggcgagg agggggccga cgccgtgccc ctgccgccac ccatggccat ccagcagcac   5640

agcctcctcc agccagactc acaggatgac aaggcctctt ctcggttatt agtccgcccc   5700

accagctccg aaacaccgag tgcagccgag ctcgtcagtg caattgagga actcgtgaaa   5760

agcaagatgg cactggagga tcgccccagc tcactccttg ttgaccaggg agatagtagc   5820

agcccttcct tcaacccttc ggataattcc cttctctctt cctcctcgcc cattgatgag   5880

atggaagaaa ggaaatccag ctctttaaag agaagacact acgttttgca agaactagtg   5940

gagacagagc gtgactatgt gcgggacctt ggctatgtgg ttgagggcta catggcactt   6000

atgaaagaag atggtgttcc tgatgacatg aaaggaaaag acaaaattgt gttcggcaac   6060

atccatcaga tttacgactg gcacagagac ttttttttag gagagttaga gaagtgcctt   6120

gaagatccag aaaaactagg atcccttttt gttaaacacg agagaaggtt gcacatgtac   6180

atagcttatt gtcaaaataa accaaagtct gagcacattg tctcagaata cattgatacc   6240

ttttttgagg acttaaagca gcgtcttggc cacaggttac agctcacaga tctgttgatc   6300

aaaccagtgc agagaatcat gaagtatcag ctgttactga aggacttcct caagtattcc   6360

aaaaaggcca gcctggatac atcagaatta gagagagctg tggaagtcat gtgcatagta   6420

cccaggcggt gcaacgacat gatgaacgtg gggcggctgc aaggattcga cgggaaaatc   6480

gttgcccagg gtaaactgct cttgcaggac acattcttgg tcacagacca agatgcagga   6540

cttctgcctc gctgcagaga gaggcgcatc ttcctctttg agcagatcgt catattcagc   6600

gaaccacttg ataaaaagaa gggcttctcc atgccgggat tcctgtttaa gaacagtatc   6660

aaggtgagtt gcctttgcct ggaggaaaat gtggaaaatg atccctgtaa atttgctctg   6720

acatcgagga cgggtgacgt ggtagagacc ttcattttgc attcatctag tccaagtgtc   6780

cggcaaactt ggatccatga aatcaaccaa attttagaaa accagcgcaa ttttttaaat   6840

gccttgacat cgccaatcga gtaccagagg aaccacagcg ggggcggcgg cggcggcggc   6900

agcgggggca gcggcggggg tgggggcagc ggcggcggcg gggcccccag tggcggcagc   6960

ggccacagtg gcggccccag cagctgcggc ggcgccccca gcacgagcag gagccggccc   7020

tcccggatcc cccagcctgt ccgacaccac ccccccgtgc tggtctcctc tgcagcctcg   7080

agccaggcag aggcagacaa gatgtcaggt acgtccaccc ccgggccctc cctgcctccc   7140

cctggcgcgg cccccgaggc cggccccagc gcgcccagca ggcggccccc cggcgcggac   7200

gccgaggggt ccgagcgaga agcggagccg atccccaaga tgaaggtgct ggagagcccc   7260

aggaaaggcg ccgcgaacgc ctcggggtcg agcccagacg cccccgccaa ggacgcgcgc   7320

gctagcctgg gcaccctgcc gcttgggaag ccccgggccg gggccgcttc gccgctgaac   7380

tcgccgctct ccagcgcggt cccttctctc ggcaaggagc ccttcccccc cagcagcccc   7440

ctgcagaagg ggggctcctt ctggagctcc atccccgcct cccccgccag ccgacccggc   7500

tccttcacct tcccggggga cagcgactcc ctccagcggc agacaccccg ccacgcggcc   7560

cctggcaagg atactgaccg catgagcacg tgctcctcgg ccagcgagca gtccgtgcag   7620

tccacccaga gcaacgggag tgaaagcagc agcagtagca acatctccac catgttggtg   7680

acacacgatt acacggcagt gaaggaggat gagatcaacg tctaccaagg agaggtcgtt   7740

caaattctgg ccagcaacca gcagaacatg tttctggtgt tccgagccgc cactgaccag   7800

tgccccgcag ctgagggctg gattccaggc tttgtcctgg gccacaccag tgcagtcatc   7860

gtggagaacc cggacgggac tctcaagaag tcaacatctt ggcacacagc actccgttta   7920

aggaaaaaat ctgagaaaaa agataaagac ggcaaaaggg aaggcaagtt agagaacggt   7980

tatcggaagt cacgggaagg actcagcaac aaggtatctg tgaagcttct caatcccaac   8040

tacatttatg acgttccccc agaattcgtc attccattga gtgaggtcac gtgtgagaca   8100

ggggagaccg ttgttcttag atgtcgagtc tgtggccgcc ccaaagcctc aattacctgg   8160

aagggccctg aacacaacac cttgaacaac gatggtcact acagcatctc ctacagtgac   8220

ctgggagagg ccacgctgaa gattgtgggc gtgaccacgg aagatgacgg catctacacg   8280

tgcatcgctg tcaatgacat gggttcagcc tcatcgtcgg ccagcctgag ggtcctaggt   8340

ccagggatgg atgggatcat ggtgacctgg aaagacaact ttgactcctt ctacagtgaa   8400

gtggctgagc ttggcagggg cagattctct gtcgttaaga aatgtgatca gaaaggaacc   8460

aagcgagcag tggccactaa gtttgtgaac aagaagttga tgaagcgcga ccaggtcacc   8520

catgagcttg gcatcctgca gagcctccag caccccctgc ttgtcggcct cctcgacacc   8580

tttgagaccc ccaccagcta catcctggtc ttagaaatgg ctgaccaggg tcgcctcctg   8640

gactgcgtgg tgcgatgggg aagcctcact gaagggaaga tcagggcgca cctgggggag   8700

gttctggaag ctgtccggta cctgcacaac tgcaggatag cacacctgga cctaaagcct   8760

gagaatatcc tggtggatga gagtttagcc aagccaacca tcaaactggc tgactttgga   8820

gatgctgttc agctcaacac gacctactac atccaccagt tactggggaa ccctgaattc   8880

gcagcccctg aaatcatcct cgggaaccct gtctccctga cctcggatac gtggagtgtt   8940

ggagtgctca catacgtact tcttagtggc gtgtccccct tcctggatga cagtgtggaa   9000

gagacctgcc tgaacatttg ccgcttagac tttagcttcc cagatgacta ctttaaagga   9060

gtgagccaga aggccaagga gttcgtgtgc ttcctcctgc aggaggaccc cgccaagcgt   9120

ccctcggctg cgctggccct ccaggagcag tggctgcagg ccggcaacgg cagaagcacg   9180

ggcgtcctcg acacgtccag actgacttcc ttcattgagc ggcgcaaaca ccagaatgat   9240

gttcgaccta tccgtagcat taaaaacttt ctgcagagca ggcttctgcc tagagtttga   9300

cctatccaga agttctttct cattctcttt cacctgccaa tcagctgtta atctgaattt   9360

tcaagagaaa acaagcaaac ataactgatc agctgccggt atgttcatcg tgtgaaattg   9420

cattccaagt gagctgtgct cagcagtgct tggacacaga gctgcaagct gcgctggggt   9480

ggaggaccgt cacttacact ctgcccaagg cagaggtcgc attgctgtat cacagtattt   9540

tattcaggtt tctgcaaaaa aataaaaaga taactttttt aaacaaacat gaatagaatt   9600

ttgcaaattt aacgttttca agatttattc aaggaaacaa aatgcctatg ttcaaccact   9660

ggtgttaatg aacaaagata ctgtgcgtct ctggggaaga cgcacctagg tggcggccac   9720

tcccatggcc ttgtctagga ctcagagacc actcggctct gagcttccag gcgcctcgtc   9780

tgtgtgcatc tcacgcccga cgtggcttct gaaacgtgca ttcaacctca aacttttgca   9840

taaaatagaa tgaatcgttt tgctctgatg aaatgtaggc cttacttgta tataagactg   9900

ttcctgcctt cggtctgtca ttttcccacc tgcctcccct acccaccccc cacccaccac   9960

ctggggcttc ctctgggggt ccgagggtct tcccatcaca tgaagacatc aggttgggtc  10020

ctgccccact gcccctcccc ctgttcctgc cccaagccgt caatcagatt gtggagcagt  10080

acacagtcag atgaaaatac tgtaaatgca ctcattgggg gttttttggt tttacttcat  10140

atcatgtgca atgttgtggc tttaacattt tatgcaacta tttatgaaga cctctgttgt  10200

acctgtaata aatatataga aaaagcaaaa aaaaaaaaaa aaaa                   10244


<210>  882
<211>  2510
<212>  DNA
<213>  Human

<400>  882
gcacctcgct gctccagcct ctggggcgca ttccaacctt ccagcctgcg acctgcggag     60

aaaaaaaatt acttattttc ttgccccata cataccttga ggcgagcaaa aaaattaaat    120

tttaaccatg agggaaatcg tgcacatcca ggctggtcag tgtggcaacc agatcggtgc    180

caagttctgg gaggtgatca gtgatgaaca tggcatcgac cccaccggca cctaccacgg    240

ggacagcgac ctgcagctgg accgcatctc tgtgtactac aatgaagcca caggtggcaa    300

atatgttcct cgtgccatcc tggtggatct agaacctggg accatggact ctgttcgctc    360

aggtcctttt ggccagatct ttagaccaga caactttgta tttggtcagt ctggggcagg    420

taacaactgg gccaaaggcc actacacaga gggcgccgag ctggttgatt ctgtcctgga    480

tgtggtacgg aaggaggcag agagctgtga ctgcctgcag ggcttccagc tgacccactc    540

actgggcggg ggcacaggct ctggaatggg cactctcctt atcagcaaga tccgagaaga    600

ataccctgat cgcatcatga ataccttcag tgtggtgcct tcacccaaag tgtctgacac    660

cgtggtcgag ccctacaatg ccaccctctc cgtccatcag ttggtagaga atactgatga    720

gacctattgc attgacaacg aggccctcta tgatatctgc ttccgcactc tgaagctgac    780

cacaccaacc tacggggatc tgaaccacct tgtctcagcc accatgagtg gtgtcaccac    840

ctgcctccgt ttccctggcc agctcaatgc tgacctccgc aagttggcag tcaacatggt    900

ccccttccca cgtctccatt tctttatgcc tggctttgcc cctctcacca gccgtggaag    960

ccagcagtat cgagctctca cagtgccgga actcacccag caggtcttcg atgccaagaa   1020

catgatggct gcctgtgacc cccgccacgg ccgatacctc accgtggctg ctgtcttccg   1080

tggtcggatg tccatgaagg aggtcgatga gcagatgctt aacgtgcaga acaagaacag   1140

cagctacttt gtggaatgga tccccaacaa tgtcaagaca gccgtctgtg acatcccacc   1200

tcgtggcctc aagatggcag tcaccttcat tggcaatagc acagccatcc aggagctctt   1260

caagcgcatc tcggagcagt tcactgccat gttccgccgg aaggccttcc tccactggta   1320

cacaggcgag ggcatggacg agatggagtt caccgaggct gagagcaaca tgaacgacct   1380

cgtctctgag tatcagcagt accaggatgc caccgcagaa gaggaggagg atttcggtga   1440

ggaggccgaa gaggaggcct aaggcagagc ccccatcacc tcaggcttct cagttccctt   1500

agccgtctta ctcaactgcc cctttcctct ccctcagaat ttgtgtttgc tgcctctatc   1560

ttgttttttg ttttttcttc tggggggggt ctagaacagt gcctggcaca tagtaggcgc   1620

tcaataaata cttgtttgtt gaatgtctcc tctctctttc cactctggga aacctaggtt   1680

tctgccattc tgggtgaccc tgtatttctt tctggtgccc attccatttg tccagttaat   1740

acttcctctt aaaaatctcc aagaagctgg gtctccagat cccatttaga accaaccagg   1800

tgctgaaaac acatgtagat aatggccatc atcctaagcc caaagtagaa aatggtagaa   1860

ggtagtgggt agaagtcact atataaggaa ggggatggga ttttccattc taaaagtttt   1920

ggagagggaa atccaggcta ttaaagtcac taaatttcta agtatgtcca tttcccatct   1980

cagcttcaag ggaggtgtca gcagtattat ctccactttc aatctccctc caagctctac   2040

tctggaggag tctgtcccac tctgtcaagt ggaatccttc cctttccaac tctacctccc   2100

tcactcagct cctttcccct gatcagagaa agggatcaag ggggttggga ggggggaaag   2160

agaccagcct tggtccctaa gcctccagaa acgtcttctt aatccccacc ttttcttact   2220

cccaaaaaag aatgaacacc cctgactctg gagtggtgta tactgccaca tcagtgtttg   2280

agtcagtccc cagaggagag gggaaccctc ctccatcttt tttgcaacat ctcatttctt   2340

ccttttgctg ttgcttcccc cctcacacac ttggttttgt tctatcctac atttgagatt   2400

tctattttat gttgaacttg ctgctttttt tcatattgaa aagatgacat cgccccaaga   2460

gccaaaaata aatgggaatt gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa              2510


<210>  883
<211>  1621
<212>  DNA
<213>  Human

<400>  883
gcggcaggtc tctgcgcagc ccagcccgcc ggtccacgcc gcgcaccgct ccgagggcca     60

gcgccacccg ctccgcagcc ggcaccatgc gcgagatcgt gcacatccag gcgggccagt    120

gcggcaacca gatcggcgcc aagttttggg aggtcatcag cgatgagcat gggatcgacc    180

ccacaggcag ttaccatgga gacagtgact tgcagctgga gagaatcaac gtgtactaca    240

atgaggctgc tggtaacaaa tatgtacctc gggccatcct ggtggatctg gagcctggca    300

ccatggactc tgtcaggtct ggacccttcg gccagatctt cagaccagac aacttcgtgt    360

tcggccagag tggagccggg aataactggg ccaagggcca ctacacagag ggagccgagc    420

tggtcgactc ggtcctggat gtggtgagga aggagtcaga gagctgtgac tgtctccagg    480

gcttccagct gacccactct ctggggggcg gcacggggtc cgggatgggc accctgctca    540

tcagcaagat ccgggaagag tacccagacc gcatcatgaa caccttcagc gtcatgccct    600

cacccaaggt gtcagacacg gtggtggagc cctacaacgc caccctctct gtccaccagc    660

tggtggaaaa cacagatgaa acctactcca ttgataacga ggccctgtat gacatctgct    720

tccgcaccct gaagctgacc acccccacct acggggacct caaccacctg gtgtcggcca    780

ccatgagcgg ggtcaccacc tgcctgcgct tcccgggcca gctgaacgca gacctgcgca    840

agctggcggt gaacatggtg cccttccctc gcctgcactt cttcatgccc ggcttcgcgc    900

ccctgaccag ccggggcagc cagcagtacc gggcgctcac ggtgcccgag ctcacccagc    960

agatgttcga ctccaagaac atgatggccg cctgcgaccc gcgccacggc cgctacctga   1020

cggtggctgc catcttccgg ggccgcatgt ccatgaagga ggtggacgag cagatgctca   1080

acgtgcagaa caagaacagc agctacttcg tggagtggat ccccaacaac gtgaagacgg   1140

ccgtgtgcga catcccgccc cgcggcctga agatgtcggc caccttcatc ggcaacagca   1200

cggccatcca ggagctgttc aagcgcatct ccgagcagtt cacggccatg ttccggcgca   1260

aggccttcct gcactggtac acgggcgagg gcatggacga gatggagttc accgaggccg   1320

agagcaacat gaacgacctg gtgtccgagt accagcagta ccaggacgcc acggccgacg   1380

aacaagggga gttcgaggag gaggagggcg aggacgaggc ttaaaaactt ctcagatcaa   1440

tcgtgcatcc ttagtgaact tctgttgtcc tcaagcatgg tctttctact tgtaaactat   1500

ggtgctcagt tttgcctctg ttagaaattc acactgttga tgtaatgatg tggaactcct   1560

ctaaaaatta cagtattgtc tgtgaaggta tctatactaa taaaaaagca tgtgtagaaa   1620

a                                                                   1621


<210>  884
<211>  3087
<212>  DNA
<213>  Human

<400>  884
ccgggcggga gtagctggtg gaccccgttg agctgccgaa cttccgggac tcccccgcga     60

ccccttccca gcttcccgtc cgctccgccg cagcgattgt ctcggtgggt tgattcggca    120

caaaccgccc gacccagggg ccggtgcgcg tgtggaaggg gaagcactcc cctcgtggtc    180

gcctggaggt gcgctggagg agggggtgac ataaccaggg actcgaggtc cgccgtggga    240

atgatccacg aactgctctt ggctctgagc gggtaccctg ggtccatttt cacctggaac    300

aagcggagtg gcctgcaggt atcgcaggac ttccctttcc tccaccccag tgagaccagt    360

gtcctgaatc gactctgccg gctcggcaca gactatattc gcttcactga gttcattgaa    420

cagtacacgg gccatgtgca acagcaggat caccatccat ctcaacaggg ccaaggtggg    480

ttacatggaa tctacctgcg ggccttctgc acagggctgg attctgtttt gcagccttat    540

cgccaagcac tgcttgattt ggaacaagag ttcctgggtg atccccatct ctccatatca    600

catgtcaact acttcctaga ccagttccag cttctttttc cctctgtgat ggttgtagta    660

gaacaaatta aaagtcaaaa gattcatggt tgtcaaatcc tggaaacagt ctacaaacac    720

agctgtgggg ggttgcctcc tgttcgaagt gcactggaaa aaatcctggc cgtttgtcat    780

ggggtcatgt ataaacagct ctcagcctgg atgctccatg gactcctctt ggaccagcat    840

gaagaattct ttatcaaaca ggggccatct tctggtaatg tcagtgccca gccagaagag    900

gacgaggagg atctgggcat tgggggactg acaggaaaac aactgagaga actgcaggac    960

ttgcgcctga ttgaggaaga gaacatgctg gcaccatctc tgaagcagtt ttccctacga   1020

gtggagattt tgccatccta cattccagtg agggttgctg aaaaaatcct atttgttgga   1080

gaatctgtcc agatgtttga gaatcaaaat gtgaacctga ctagaaaagg atccattttg   1140

aaaaaccagg aagacacttt tgctgcagag ctgcaccgtc tcaagcagca gccactcttc   1200

agcttggtgg actttgaaca ggtggtggat cgcattcgca gcactgtggc tgagcatctc   1260

tggaagttga tggtagaaga atccgattta ctgggtcagc tgaagatcat taaagacttt   1320

taccttctgg gacgtggaga actgtttcag gccttcattg acacagctca acacatgttg   1380

aaaacaccac ccactgcagt aactgagcat gatgtgaatg tggcctttca acagtcagca   1440

cacaaggtat tgctagatga tgacaacctt ctccctctgt tgcacttgac aatcgagtat   1500

cacggaaagg agcacaaaga tgctactcag gcaagagaag ggccttctcg ggaaacttct   1560

ccccgggaag cccctgcatc tggctgggca gccctaggtc tttcctacaa agtacagtgg   1620

ccactacata ttctcttcac cccagctgtc ctggaaaagt acaatgttgt ttttaagtac   1680

ttactgagtg tgcgccgggt gcaagctgag ctgcagcact gctgggccct acaaatgcag   1740

cgcaagcacc tcaagtcgaa ccagactgat gcaatcaagt ggcgcctaag aaatcacatg   1800

gcatttttgg tggataatct tcagtactat ctccaggtag atgtgttgga gtctcagttc   1860

tcccagctgc ttcatcagat caattctacc cgagactttg aaagcatccg attggctcat   1920

gaccacttcc tgagcaattt gctggctcaa tcctttatcc tattgaaacc tgtgtttcac   1980

tgcctgaatg aaatcctaga tctctgtcac agtttttgtt cgctggtcag tcagaaccta   2040

ggcccactgg atgagcgtgg agccgcccag ctgagcattc tcgtgaaggg ctttagccgc   2100

cagtcttcac tcctgttcaa gattctctcc agtgttcgga atcatcagat caactcagat   2160

ttggctcaac tactgttacg actagattat aacaaatact atacccaggc tggtggaact   2220

ctgggcagtt tcgggatgtg aaaatttctg gctcataaat tgaaataaca gccacgttcc   2280

caaggttgta acagaagatt caaaacatcc cattctagcc acacacaaat aaatatctgc   2340

ggcttagtga taggactcta ccttttctcc tagaagcagt tactgaacat ccaggagtac   2400

aactccttcc catcattccc atgtggaagg gtctctccca tcaaggagaa catgtggcat   2460

ctctgatcct ttacattgag aacatttgtt ggatatgttc atttattcaa tagtcattta   2520

ttgagcacct actacgtacc ttggtactgt tcaagctgtg ggagatacag cggtaaacaa   2580

acaatataga gcagaaagtt aaatatttta tggttcatat gtgaaaaagt aattatgttt   2640

ataaatagac taactgctgg atgttaccac caagtaagaa agcaacaggt aagataggct   2700

ttctctctcc ctataccaag taatttatac ctacacagat tgggcaattc tagctaatga   2760

aaatatactt aaaagtattt cttaggccgg gcatggtggc tcacacctgt aatcccagca   2820

ctttgggagg ccgaggcggg cggatcacct gaagtcagga gtttgagacc agcctgacca   2880

acatgatgaa acctcgattc tactaaaaat acaaaaatta gccaggtgtg gtggcatgtg   2940

cctgtaatcc cagctactca ggaggctgag acaggagaat tgcttgaacc tgggaagcag   3000

acgctgcagt gagctgagat tgtgccattg cattccagcc cgggcaacaa gagcgaaatt   3060

ccgtctcaaa aaaaaaaaaa aaaaaaa                                       3087


<210>  885
<211>  1877
<212>  DNA
<213>  Human

<400>  885
ccgcgacggc gcgcccccgg cggctgctgc ggcggcggga gcgaggcgac cgctgaggcc     60

gcggagagtg acggcggccc ggccgacggg agccggggcg gggcggcggc ccagcgaagg    120

agcgcgcggg cggtctggcc ccgccccctc cccgcccgcc ttcccggtga ccttcagggg    180

cccgggtggc gggcgcaggc ccctgcggcg gcggcgggat gttcgtgcag gaggagaaga    240

tcttcgcggg caaggtgctg cggctgcaca tctgcgcgtc cgacggcgcc gagtggctgg    300

aggaggccac cgaggacacc tcggtggaga agctcaagga gcgctgcctc aagcactgtg    360

ctcatgggag cttagaagat cccaaaagta taacccatca taaattaatc cacgctgcct    420

cagagagggt gctgagtgat gccaggacca tcctggaaga gaacatccag gaccaagatg    480

tcctattatt gataaaaaag cgtgctccat caccacttcc caagatggct gatgtctcag    540

cagaagaaaa gaaaaaacaa gaccagaaag ctccagataa agaggccata ctgcgggcca    600

ccgccaacct gccctcctac aacatggacc gggccgcggt ccagaccaac atgagagact    660

tccagacaga actccggaag atactggtgt ctctcatcga ggtggcgcag aagctgttag    720

cgctgaaccc agatgcggtg gaattgttta agaaggcgaa tgcaatgctg gacgaggacg    780

aggatgagcg tgtggacgag gctgccctgc ggcagctcac ggagatgggc tttccggaga    840

acagagccac caaggccctt cagctgaacc acatgtcggt gcctcaggcc atggagtggc    900

taattgaaca cgcagaagac ccgaccatag acacgcctct tcctggccaa gctcccccag    960

aggccgaggg ggccacagca gctgcctccg aggctgccgc gggagccagc gccaccgatg   1020

aggaggccag agatgagctg acggaaatct tcaagaagat ccggaggaaa agggagtttc   1080

gggctgatgc tcgggccgtc atttccctga tggagatggg gttcgacgag aaagaggtga   1140

tagatgccct cagagtgaac aacaaccagc agaatgccgc gtgcgagtgg ctgctggggg   1200

accggaagcc ctctccggag gagctggaca agggcatcga ccccgacagt cctctctttc   1260

aggccatcct ggataacccg gtggtgcagc tgggcctgac caacccgaaa acattgctag   1320

catttgaaga catgctggag aacccactga acagcaccca gtggatgaat gatccagaaa   1380

cggggcctgt catgctgcag atctctagaa tcttccagac actaaatcgc acgtaggtgg   1440

cgttgttcca ctcggctatc aggccacagc agccccctgg tgcggcccga gaccgggcag   1500

agtggacctc acctggaaac tcaccttcag cgcctcagcc ctggactgtt agaggtgctg   1560

cagctgctcc tgctctctga tcttattgct tataaacttt ggtgacggta gtgtgtaagg   1620

ccgtattttt agcatctgac aggtgtttac aaaaaagtgg ttgtcgcact gggaagtgga   1680

gtgatggcct cgtctccagt gctcctctgg gctcttgagt tgctgcttga attgccgtgt   1740

agacatttgc ttggagagtc cacttgttat ttgacggagg taggtttcaa cccagagtta   1800

atgtcaagca tgctaattta actagtcact cacagatgac ttttctttaa taaagtccct   1860

tttcctaaaa aaaaaaa                                                  1877


<210>  886
<211>  2594
<212>  DNA
<213>  Human

<400>  886
aggggccgcg gagccgcggc taaggaacgc gggccgccca cccgctcccg gtgcagcggc     60

ctccgcgccg ggttttggcg cctcccgcgg gcgcccccct cctcacggcg agcgctgcca    120

cgtcagacga agggcgcagc gagcgtcctg atccttccgc ccggacgctc aggacagcgg    180

cccgctgctc ataagactcg gccttagaac cccagtatca gcagaaggac attttaggac    240

gggacttggg tgactctagg gcactggttt tctttccaga gagcggaaca ggcgaggaaa    300

agtagtccct tctcggcgat tctgcggagg gatctccgtg gggcggtgaa cgccgatgat    360

tatataagga cgcgccgggt gtggcacagc tagttccgtc gcagccggga tttgggtcgc    420

agttcttgtt tgtggatcgc tgtgatcgtc acttgacaat gcagatcttc gtgaagactc    480

tgactggtaa gaccatcacc ctcgaggttg agcccagtga caccatcgag aatgtcaagg    540

caaagatcca agataaggaa ggcatccctc ctgaccagca gaggctgatc tttgctggaa    600

aacagctgga agatgggcgc accctgtctg actacaacat ccagaaagag tccaccctgc    660

acctggtgct ccgtctcaga ggtgggatgc aaatcttcgt gaagacactc actggcaaga    720

ccatcaccct tgaggtcgag cccagtgaca ccatcgagaa cgtcaaagca aagatccagg    780

acaaggaagg cattcctcct gaccagcaga ggttgatctt tgccggaaag cagctggaag    840

atgggcgcac cctgtctgac tacaacatcc agaaagagtc taccctgcac ctggtgctcc    900

gtctcagagg tgggatgcag atcttcgtga agaccctgac tggtaagacc atcaccctcg    960

aggtggagcc cagtgacacc atcgagaatg tcaaggcaaa gatccaagat aaggaaggca   1020

ttccttctga tcagcagagg ttgatctttg ccggaaaaca gctggaagat ggtcgtaccc   1080

tgtctgacta caacatccag aaagagtcca ccttgcacct ggtactccgt ctcagaggtg   1140

ggatgcaaat cttcgtgaag acactcactg gcaagaccat cacccttgag gtcgagccca   1200

gtgacactat cgagaacgtc aaagcaaaga tccaagacaa ggaaggcatt cctcctgacc   1260

agcagaggtt gatctttgcc ggaaagcagc tggaagatgg gcgcaccctg tctgactaca   1320

acatccagaa agagtctacc ctgcacctgg tgctccgtct cagaggtggg atgcagatct   1380

tcgtgaagac cctgactggt aagaccatca ctctcgaagt ggagccgagt gacaccattg   1440

agaatgtcaa ggcaaagatc caagacaagg aaggcatccc tcctgaccag cagaggttga   1500

tctttgccgg aaaacagctg gaagatggtc gtaccctgtc tgactacaac atccagaaag   1560

agtccacctt gcacctggtg ctccgtctca gaggtgggat gcagatcttc gtgaagaccc   1620

tgactggtaa gaccatcact ctcgaggtgg agccgagtga caccattgag aatgtcaagg   1680

caaagatcca agacaaggaa ggcatccctc ctgaccagca gaggttgatc tttgctggga   1740

aacagctgga agatggacgc accctgtctg actacaacat ccagaaagag tccaccctgc   1800

acctggtgct ccgtcttaga ggtgggatgc agatcttcgt gaagaccctg actggtaaga   1860

ccatcactct cgaagtggag ccgagtgaca ccattgagaa tgtcaaggca aagatccaag   1920

acaaggaagg catccctcct gaccagcaga ggttgatctt tgctgggaaa cagctggaag   1980

atggacgcac cctgtctgac tacaacatcc agaaagagtc caccctgcac ctggtgctcc   2040

gtcttagagg tgggatgcag atcttcgtga agaccctgac tggtaagacc atcactctcg   2100

aagtggagcc gagtgacacc attgagaatg tcaaggcaaa gatccaagac aaggaaggca   2160

tccctcctga ccagcagagg ttgatctttg ctgggaaaca gctggaagat ggacgcaccc   2220

tgtctgacta caacatccag aaagagtcca ccctgcacct ggtgctccgt ctcagaggtg   2280

ggatgcaaat cttcgtgaag accctgactg gtaagaccat caccctcgag gtggagccca   2340

gtgacaccat cgagaatgtc aaggcaaaga tccaagataa ggaaggcatc cctcctgatc   2400

agcagaggtt gatctttgct gggaaacagc tggaagatgg acgcaccctg tctgactaca   2460

acatccagaa agagtccact ctgcacttgg tcctgcgctt gagggggggt gtctaagttt   2520

ccccttttaa ggtttcaaca aatttcattg cactttcctt tcaataaagt tgttgcattc   2580

ccaaaaaaaa aaaa                                                     2594


<210>  887
<211>  3223
<212>  DNA
<213>  Human

<400>  887
cggcggcggc ggcggcggcg gcggcggcgg agcccggagc gcaggccgga ggctcccggc     60

ccgccggccc cggagcggag cggagcggag gatgcagcag ccgcagccgc aggggcagca    120

gcagccgggg ccggggcagc agctgggggg ccagggggcg gcgccggggg ccgggggcgg    180

cccagggggg ggcccggggc cggggccctg cctgaggcga gagctgaagc tgctcgagtc    240

catcttccac cgcggccacg agcgcttccg cattgccagc gcctgcctgg acgagctgag    300

ctgcgagttc ctgctggctg gggccggagg ggccggggcg ggggccgcgc ccggaccgca    360

tctcccccca cgggggtcgg tgcctgggga tcctgtccgc atccactgca acatcacgga    420

gtcataccct gctgtgcccc ccatctggtc ggtggagtct gatgacccta acttggctgc    480

tgtcttggag aggctggtgg acataaagaa agggaatact ctgctattgc agcatctgaa    540

gaggatcatc tccgacctgt gtaaactcta taacctccct cagcatccag atgtggagat    600

gctggatcaa cccttgccag cagagcagtg cacacaggaa gacgtgtctt cagaagatga    660

agatgaggag atgcctgagg acacagaaga cttagatcac tatgaaatga aagaggaaga    720

gccagctgag ggcaagaaat ctgaagatga tggcattgga aaagaaaact tggccatcct    780

agagaaaatt aaaaagaacc agaggcaaga ttacttaaat ggtgcagtgt ctggctcggt    840

gcaggccact gaccggctga tgaaggagct cagggatata taccgatcac agagtttcaa    900

aggcggaaac tatgcagtcg aactcgtgaa tgacagtctg tatgattgga atgtcaaact    960

cctcaaagtt gaccaggaca gcgctttgca caacgatctc cagatcctca aagagaaaga   1020

aggagccgac ttcattctac ttaacttttc ctttaaagat aactttccct ttgacccacc   1080

atttgtcagg gttgtgtctc cagtcctctc tggagggtat gttctgggcg gaggggccat   1140

ctgcatggaa cttctcacca aacagggctg gagcagtgcc tactccatag agtcagtgat   1200

catgcagatc agtgccacac tggtgaaggg gaaagcacga gtgcagtttg gagccaacaa   1260

atctcaatac agtctgacaa gagcacagca gtcctacaag tccttggtgc agatccacga   1320

aaaaaacggc tggtacacac ccccaaaaga agacggctaa ccctggagta tcacccttcc   1380

tccctcccca ggcaccactg gaccaattac ctttgaatgc tgtatttgga tctcacgctg   1440

cctctgtggt tccctccctc atttttcctg gacgtgatag ctctgcctat tgcaggacaa   1500

tgatggctat tctaaacgct aaggaaaaaa aacaaacaca gaactgtttc aagtactcaa   1560

gactgactta cagaccaacc aaccaccttg ctggaaccct tgctagcagg cattcttata   1620

aaagaaactt tcgagcctcc ttatattgct ggaaactcag ctgtgctcca gactagagcc   1680

tccttaccta tgctatggat ttttaattta ttttctctta tttcatgtac actgcttttt   1740

ttggttacag tgtatgatgg atgtgtatga aaaaaatgta tctttgggaa aacaattaca   1800

gtttgttaat ttgaagatgc tggtcttgac tcatctttat ttttattcgc acatcccacc   1860

ccatcccctg aactacttgg gaggtgggga ggggtacgag tccactgttg ctttggtaga   1920

gatgagaggc cgcattttgc tgctaaagca agagaaactt ggagctgaag cacacacctg   1980

gtctgcccct agatttctcc tcaaggcctc tggagcaacc agcacttgcc cccttggaat   2040

gcagagcctg gcctgccaaa ctacaatgtg gtaggctgaa acgatggtgt taattcttag   2100

gactactttt ctagtcacag atgttttcaa atttctaaga aaaagaaaat gaggctcaag   2160

aggctgcttc gtagaattcc ttttgaatga attgagtggg gatggggaca cagtctccaa   2220

gtgtgtatgt ggtcttttct gatctcagct gtgtggctgc aactcttcgc tgttcattgg   2280

ttcctctcct ggaaagtggc ttctaaccag cactggatgg tgatcattgg taagctttgc   2340

tcacctccct ctctcttgct tcatttggct ttatcaaaaa gaacagacct agctctgaat   2400

ttgtttggct tgggaaatta tggattcttt caagccactc ccacaaggtg ggtcctacta   2460

gaaagggtta gcattttaag gggggttgtt ctatacacct gtgtccttac cccaggctca   2520

ggaactgcca gggagggaag atgaggtggg gagtctgtac tgagatggaa ctgtcagtgc   2580

tgtgttgtat gtacttgctg ttgtaaaagt ttgggcatga ctttgcatct agcgggtgct   2640

gcctgcatct ctttgtctgt aagcttgctc tgggactcag cctcttagga cctacgatgc   2700

cagcagctct cattaacagt gaaatgacag aggccaaaga tggccaagtg aagacccaag   2760

tctcagaaaa cccagacttg ggacaactgc ctgggaacta ggatgctaga gcagttctgt   2820

aatgctttga gacacagcaa ttttcacatt ggccattctt tcccctcccc tacccctttt   2880

cttttgaggg acttttaatg tttgctgctt taggtggatg gagagtccac cagtcccact   2940

caatgctgct ctaactctac ccacacccac ctaattaggg gtgctaataa aacatgctga   3000

ggttgagata aagacgggac ataaggggaa aattcattcc atagagctga aatctggttt   3060

tcaaggcctc tgtggctttc ttctgaactt accaccagcc ctggctggaa tgtagattgt   3120

gtttttagta atgtgtactg tgagctgtct tctgtataat gtattttgta atgtattttt   3180

ctcatctacc aaaggatgaa acaaataaaa ttatttaaat agt                     3223


<210>  888
<211>  2365
<212>  DNA
<213>  Human

<400>  888
gcatttgttg ggggcggagc tttgacggga gcttcccggg agccgtttgt gcccggggta     60

accccgttcc ggccaagccg cttcagcggg ggacgtagcc atgaaggaag agaaggagca    120

caggcctaag gagaagcgag taaccctgtt aacccccgcc ggggccacag gcagcggtgg    180

tgggacctcg ggggacagct ccaaggggga agataagcag gatcgcaaca aggagaagaa    240

agaagcgctg agcaaggtgg taattcgaag attacctccc actttgacca aggagcagct    300

tcaggaacat cttcaaccta tgcctgagca tgattatttt gagttttttt ctaatgatac    360

gagtttgtat cctcatatgt atgccagagc atacatcaac tttaaaaacc aagaggacat    420

tattttgttc agggatcgct ttgatggtta tgtattcctt gacaataaag gtcaggaata    480

tcccgctata gtagaatttg caccttttca aaaagctgca aaaaagaaga ctaagaaaag    540

agataccaaa gtcgggacta tcgatgatga tccagaatat agaaagtttt tggaaagtta    600

tgccacagat aatgagaaaa tgacatctac tccagagaca ctgctagagg aaatagaagc    660

aaaaaataga gaattaatag ctaaaaagac aaccccactt ttgagcttcc tgaaaaacaa    720

gcagagaatg agagaagaaa agagagaaga aaggaggagg agagaaatag aaagaaaaag    780

acaaagagaa gaagagagga ggaaatggaa agaagaagag aaacgaaaaa ggaaagatat    840

agaaaagcta aagaagatag acagaattcc agaaagggac aaattaaagg atgaaccaaa    900

gattaagctg ctcaagaagc cagaaaaagg agatgaaaaa gaattggaca aaagagaaaa    960

agccaagaaa ttggacaaag agaatctcag tgatgaaaga gccagtgggc aaagttgtac   1020

attgcccaag cgttctgata gcgaacttaa agatgaaaaa ccaaagagac ctgaagatga   1080

gagcggcaga gactataggg agagggaacg ggaatatgaa cgagatcagg agcgcatact   1140

tcgagaaaga gagaggctga agcggcaaga agaagagcgc cgtaggcaga aggagcgcta   1200

tgagaaagag aagactttta agagaaaaga agaagaaatg aaaaaagaga aagacacact   1260

tcgggataaa ggaaagaagg ctgaaagtac agaatcaata ggcagctcag aaaaaactga   1320

aaagaaagaa gaagtggtca agagagatcg aataagaaac aaggatcgtc cagcgatgca   1380

gctttaccaa ccaggagctc gaagccgaaa tcgactctgt ccccctgatg acagcaccaa   1440

gtctggagat tcagcagcag aaaggaagca ggaaagtggt attagccata gaaaagaagg   1500

aggagaggag tgataagtcc agatggcctt aggtgtcctg actgtctagg cagccaaaga   1560

gcacacgtta agcaatccag aggtgccttc agggcaaaga atagagagaa agggagccgc   1620

tgtgctggtg gggtacactg cagaggagta agtcttgtgt caaagcagga atctgatcag   1680

aggttcagaa ttggaagtac aatttcattg cttttgcaat ttctacaaat taattttaaa   1740

gtgtcagaaa aaggtgacgg caaggacatg cattgcaatt tgcaggggga attgtcaagt   1800

gaggacttca tcacatatga cacgagagaa aagtaagagc tggttctaaa atcaaaagct   1860

gttgttcatc ctgaattgaa ttttctgaat ttgggtggag cagagtcgct ttgaagcctt   1920

gttccgatct aattctattg tattgttgat gataagtgtt gacattgggt agtgtagaag   1980

caacaagcat gtccttgtag tacaggtaca gtgaaggata gaacacactt tcgttgatac   2040

aaaaatttaa atagttatgt tacttctgta tccagtgtcc taaagtttta ggattagttt   2100

tagttttttg tttgcttata tgagcttagc gtaaagaata tttttaaact tcgtgttttg   2160

tcatcagcat cttttctatt aagaggtaaa atgtagtcct tgtttgactc ttgacaatcc   2220

agtgtgtttg atcttaggtc tcatgatctg agtgcatacc ctctccagga aggaaactgc   2280

accagtgtct attcctgtta aatagcaact tttagtctca gcttgtttcg ttttgatgtc   2340

aataaatagt aacagcattc aagtg                                         2365


<210>  889
<211>  1796
<212>  DNA
<213>  Human

<400>  889
ggtcagctga gttcgccggc ccagggcagg cggggcccga gcctagcggt aacccccggg     60

cagggcgggg ccgctcgcag actccatatg agattcacct cgcaggtggt tccctcattc    120

gagtgctccg gcgcacagac ccgcgccccg ccgtctgcga gcctcccgag agccgtccct    180

tcgtccggcc ctggagcatt gcgtttgtcg ccggtgtcgc agtgcgagga tggcgccgcg    240

ggtgtagcgg ctctctgcgc aggccgagtg ggcccagaga agcgaggaac tccgcagctc    300

gtcgacacgt ctcgtctcct gtcccaattc agggcttggt gaggtgactc gcggtcgcgg    360

gtgactcgcc ggcaggacac tgcctggaac gcctggagcg cctcccactg cagacgtctg    420

tccgcctcca gccgctctcc tctgacgggt cctgcctcag ttggcggaat ggcggccacg    480

ggagccaatg cagagaaagc tgaaagtcac aatgattgcc ccgtcagact tttaaatcca    540

aacatagcaa aaatgaaaga agatattctc tatcatttca atctcaccac tagcagacac    600

aatttcccag ccttgtttgg agatgtgaag tttgtgtgtg ttggtggaag cccctcccgg    660

atgaaagcct tcatcaggtg cgttggtgca gagctgggcc ttgactgccc aggtagagac    720

tatcccaaca tctgtgcggg aactgaccgc tatgccatgt ataaagtagg accggtgctg    780

tctgtcagtc atggtatggg cattccttct atctcaatca tgttgcatga gctcataaag    840

ctgctgtact atgcccggtg ctccaacgtc actatcatcc gcattggcac ttctggtggg    900

ataggtctgg agcccggcac tgtggtcata acagagcagg cagtggatac ctgcttcaag    960

gcagagtttg agcagattgt cctggggaag cgggtcatcc ggaaaacgga ccttaacaag   1020

aagctggtgc aggagctgtt gctgtgttct gcagagctga gcgagttcac cacagtggtg   1080

gggaacacca tgtgcacctt ggacttctat gaagggcaag gccgtctgga tggggctctc   1140

tgctcctaca cggagaagga caagcaggcg tatctggagg cagcctatgc agccggcgtc   1200

cgcaatatcg agatggagtc ctcggtgttt gccgccatgt gcagcgcctg cggcctccaa   1260

gcggccgtgg tgtgtgtcac cctcctgaac cgcctggaag gggaccagat cagcagccct   1320

cgcaatgtgc tcagcgagta ccagcagagg ccgcagcggc tggtgagcta cttcatcaag   1380

aagaaactga gcaaggcctg agcgctgccc tgcacctccg cagacctgct gtgatgactt   1440

gccattaaaa gcattgtcca aaatcccctg ttgtgtggac tttgagcaca ctttacacaa   1500

gaatctagaa aatcagatcg cgattaagag acagagaatc ttggattaac cgcatgggag   1560

atgttcttcc ttttgaagtt tcattggagc attttcaatg atgttagcct gatttggggt   1620

ttcttcaaga acattctacc aaatttttgt actatttcta gggaaatttt tcagacttta   1680

aaattctaat ggtagtcaga tttcatgtca ctaaacaaga aatctgacaa tagtgccagg   1740

aaactaattt cctgatacat taaaaaaatt ccatgcaaaa aaaaaaaaaa aaaaaa       1796


<210>  890
<211>  4659
<212>  DNA
<213>  Human

<400>  890
tgtccctgcg tgtcggggtc cgctcgtgcg cgcctctccg gggtctgtgc gcgtggccct     60

ccgctcgcgc cggagggcgt gggcgtggcc tcggcgtggg tgtggccgct cggggagggg    120

cctcccgggg gcggggccgg cctggtccgc gcggtgacgc gccctgcagc cccgagcgag    180

cgagcgagcg agcgagttgc cgagcgcgcc ccgtccctcg cgcgcgatgc tcccctggac    240

ggcgctcggc ctggccctga gcttgcggct ggcgctggcg cggagcggcg cggagcgcgg    300

tccaccagca tcagcccccc gaggggacct gatgttcctg ctggacagct cagccagcgt    360

ctctcactac gagttctccc gggttcggga gtttgtgggg cagctggtgg ctccactgcc    420

cctgggcacc ggggccctgc gtgccagtct ggtgcacgtg ggcagtcggc catacaccga    480

gttccccttc ggccagcaca gctcgggtga ggctgcccag gatgcggtgc gtgcttctgc    540

ccagcgcatg ggtgacaccc acactggcct ggcgctggtc tatgccaagg aacagctgtt    600

tgctgaagca tcaggtgccc ggccaggggt gcccaaagtg ctggtgtggg tgacagatgg    660

cggctccagc gaccctgtgg gcccccccat gcaggagctc aaggacctgg gcgtcaccgt    720

gttcattgtc agcaccggcc gaggcaactt cctggagctg tcagccgctg cctcagcccc    780

tgccgagaag cacctgcact ttgtggacgt ggatgacctg cacatcattg tccaagagct    840

gaggggctcc attctcgacg cgatgcggcc gcagcagctc catgccacgg agatcacgtc    900

cagcggcttc cgcctggcct ggccacccct gctgaccgca gactcgggct actatgtgct    960

ggagctggtg cccagcgccc agccgggggc tgcaagacgc cagcagctgc cagggaacgc   1020

cacggactgg atctgggccg gcctcgaccc ggacacggac tacgacgtgg cgctagtgcc   1080

tgagtccaac gtgcgcctcc tgaggcccca gatcctgcgg gtgcgcacgc ggcccggtga   1140

ggcagggccg ggggcttcgg gcccggagtc gggggctggg ccggccccca cgcagctcgc   1200

cgccctcccc gccccagagg aggccgggcc agagcgcatc gtcatctccc acgcccggcc   1260

gcgcagcctc cgcgtgagtt gggccccagc gctgggctca gccgcggcgc tcggctacca   1320

cgtgcagttc gggccgctgc ggggcgggga ggcgcagcgg gtggaggtgc ccgcgggccg   1380

caactgcacc acgctgcagg gcctggcgcc gggcaccgcc tacctggtga ccgtgaccgc   1440

cgccttccgc tcgggccgcg agagcgcgct gtccgccaag gcctgcacgc ccgacggccc   1500

gcgcccgcgc ccacgccccg tgccccgcgc cccgaccccg gggaccgcca gccgtgagcc   1560

gtaagccggc gtccccgccc agccgagagg gccggcgcct acctgagggc ccctgtgtcc   1620

cgaacccgga gcggaggcgc ccaacccggc agacgggtgc aggcccggcc tttccccacg   1680

cggactccgc gcgaccccgg ccctctccct gcggccgcag ggcttccccg cctggcgcct   1740

gccctccagg gctggggcct cgcctggcgg gaccccgcag cagccccggc cccatccccg   1800

cccagagccg ggcgtcgtgt gggtccgtgg gtgataattg agagcgtcag acccaggact   1860

gttcagggag gagccccggt cagactccca cgtgtgaaga ccgggcccca agtggcaagg   1920

gctggcctgg ggcgggcagc ttgggtcctg gacgttgata ggaagcggaa ggggaatcgc   1980

gggaagctgg cccaggtcag gtccgcaaag gcttctgaag aagaggaagg gcgagtaggg   2040

gcacctggac gctgatggtg gccaggatgc tcagctggcc aggagggcag cacctgctgg   2100

ggacggtggc cctgccttca tgcccaggac accagctggg tccagctagc agccactggg   2160

aatcagagga atggggcaga gctgggcatt caggaccttg aggacacgtg accccacccg   2220

cccaccgcca ctatcaggcc ccgggaccgc actgacagga aaccttccgt cgtgagggag   2280

cacttcccag gggccgcagg gacgacactc tccagggagg ccccagcaac cacaccatct   2340

tcttgctgtg agaggtctca ccccgggcta cctcctgtca ctactcactg ccctggggtc   2400

cgtgggcaag ttgcccaggg tgggggtgcc tagccaggtg cagtccccgc cccgcctagt   2460

cctcggcgtc acgcaatgct cacctcgcct cttccccact aacatcccag actttaaaat   2520

tcagtaaatc agatgtacac cgagcctgca gtctcgctag gatgctttac tcctccacaa   2580

acagcagccg ccgacaggac agcttgtgaa cgtctccgcc ttttggggtg tccggggaga   2640

ggaggtggag ctgtcccctc ccagtgtcag gcctccttgg tcctcatgtg caccttttat   2700

tcagagagct tgggccccct tcctttggag ctgggcccag ggcaggtggc tggaatgcag   2760

aggacaaggg ggctggggcc tctgcagggc cattcccacc gcagtctctg ccacggcccg   2820

gagccctggg cccagggcca cgcgggctcc ctctgctggc aaagccacac cctgcaccgc   2880

atggggtcca ctgccccttt ccccacgtgg actctgcgtg accccaggaa ctgcagcatt   2940

gaggtggtct cagtccctcc ctcaggtctg gtgggcattg tgccaggggc caccttcggg   3000

acagctggcc ttggcaccgt ctcccaagaa cccagctctg tgcatcccgt ggccccacca   3060

gaaacccaag gccacaccgc ccaccagctg ggtgtggtca ccattcatgg agggccggct   3120

ggggccaggc tcaccacgca gagtttgccc tccggtgtga tgatgcatga gacacagtag   3180

gcccccctgc ctgtgtgtgc agggggtgtc tgtggggggg ccctgctggc tggactttgg   3240

gtttctcctg agctcccctt agcccccaag tcaggccacg gaggcctgag taggacccat   3300

gggctgtgtg tgtcactgca ggtggcgtgc tcacaactgc actgctggtc ggcaggtggc   3360

cagggttgca ggcccgggcc tcgggcccca cctcctctgg aggggtagga tctccttcgt   3420

gcagcccctg ccccctaccc tgttctccgg agtgttggca gatctgagcc cacggtcacg   3480

tgagaggaga tgcctcttgc acactgagcc caggcccagc tcacggagca ccctgcaggt   3540

ggcagcgggg caccaggggc tcattcctgg tggcctcagt ggcttctgtg gacgactcag   3600

actcacatga gaagctggga ggagctccag ctctgcaatc ccgagagggc agagcggggg   3660

ccctggccac aaccctgctc cccacatacc cgtctggcag aggctctgcc tcccctctgc   3720

ccatctctgc acaccaaggc tgagcacagc acaaggcctc acggagaggg tgaaaaggca   3780

ctgccgtctc catctcagtg ccaaggaatg cccctttcag aagccctcgt ctgagaagtg   3840

ctgcccctta tgtagcccca ggcattttaa aatctttgaa tctgcaccaa gtctcagaac   3900

agctctggcc ccggagtgct ccgtccaggc cgctgtgaac cggctgtccc cgcgtctcct   3960

ccacctcccc tgacacaatc ctggccccga ctcagtccac ccagggtgca gtgcagaggc   4020

tgatacccgc caggacttcc ttgccaaggg cccggccacg tcacaaggcc actgcacgct   4080

tttcgacatg cacctggaaa tcgggaaggg ccatgctgca gttgcttcta gttgagacga   4140

gaagagcgac aaggttgtga tccacgtggc aggtgttcag aaggctgggg gcgggcagcg   4200

ctggggagag ccctgggtac ttcgaggaga ccccgaaggg aggctgctcc cacacctgcg   4260

ccagtttcca ccctctctgt gagcagggct gcggtcacct cccacatctg aagagaacca   4320

acctgaggat ttcacgctgg ctgcgtgcca gaccagtccc tgacaggttg tgcgaggccc   4380

ttcgctggac agcccattgc tggccactgg acggagaggc agagggggct gaaattcggg   4440

cccatgcctc tgtgagcgat gacggagcaa cagctctcca gcacgtgaag ctctccagac   4500

agctgttcgt gagaagccag acagaggcct ggggtctcag tccagatttc tggggagtgg   4560

ggtgtccaag cgtgggccac gctgctggga gccacctagg gaagcaggtc gcctgtttct   4620

atagtgacgg taataaacca agtcaatttt ctatagtga                          4659


<210>  891
<211>  2833
<212>  DNA
<213>  Human

<400>  891
ggcctggccg gggcgggcgg cgcgggggcg gcatgagggc ccgcggcccg gggggctgag     60

gcgcccgccg cctgccgcgg gggccgctcg cgtcctccat ggaggccgga gaggaaccgc    120

tgctgctggc cgaactcaag cccgggcgcc cccaccagtt tgattggaag tccagctgtg    180

aaacctggag cgtcgccttc tccccagatg gctcctggtt tgcttggtct caaggacact    240

gcatcgtcaa actgatcccc tggccgttgg aggagcagtt catccctaaa gggtttgaag    300

ccaaaagccg aagtagcaaa aatgagacga aagggcgggg cagcccaaaa gagaagacgc    360

tggactgtgg tcagattgtc tgggggctgg ccttcagccc gtggccttcc ccacccagca    420

ggaagctctg ggcacgccac cacccccaag tgcccgatgt ctcttgcctg gttcttgcta    480

cgggactcaa cgatgggcag atcaagatct gggaggtgca gacagggctc ctgcttttga    540

atctttccgg ccaccaagat gtcgtgagag atctgagctt cacacccagt ggcagtttga    600

ttttggtctc cgcgtcacgg gataagactc ttcgcatctg ggacctgaat aaacacggta    660

aacagattca agtgttatcg ggccacctgc agtgggttta ctgctgttcc atctccccag    720

actgcagcat gctgtgctct gcagctggag agaagtcggt ctttctatgg agcatgaggt    780

cctacacgtt aattcggaag ctagagggcc atcaaagcag tgttgtctct tgtgacttct    840

cccccgactc tgccctgctt gtcacggctt cttacgatac caatgtgatt atgtgggacc    900

cctacaccgg cgaaaggctg aggtcactcc accacaccca ggttgacccc gccatggatg    960

acagtgacgt ccacattagc tcactgagat ctgtgtgctt ctctccagaa ggcttgtacc   1020

ttgccacggt ggcagatgac agactcctca ggatctgggc cctggaactg aaaactccca   1080

ttgcatttgc tcctatgacc aatgggcttt gctgcacatt ttttccacat ggtggagtca   1140

ttgccacagg gacaagagat ggccacgtcc agttctggac agctcctagg gtcctgtcct   1200

cactgaagca cttatgccgg aaagcccttc gaagtttcct aacaacttac caagtcctag   1260

cactgccaat ccccaagaaa atgaaagagt tcctcacata caggactttt taagcaacac   1320

cacatcttgt gcttctttgt agcagggtaa atcgtcctgt caaagggagt tgctggaata   1380

atgggccaaa catctggtct tgcattgaaa tagcatttct ttgggattgt gaatagaatg   1440

tagcaaaacc agattccagt gtactagtca tggatctttc tctccctggc atgtgaaagt   1500

cagtcttaga ggaagagatt ccacttgcac ggcaacagag ccttacgtta aattttcagt   1560

ccagttatga acagcaagtg ttgaactctt tctgcttgtt ttgattcaaa gtgcagttac   1620

tgatgttgtt ttgattatgc aactaagtag gcctccagag cctctctagt ggcagagcag   1680

ctcacactcc ctccgctggg aacgatggct tctgcctagt acctatcctt gtgtttctga   1740

tgcagtggta gcattggttc aagttctctc ctgctgtggt cagagttgct tcgatgttgg   1800

ccaagtgctt ttcttcttgg gctcccttct gacctgcagg acagttttcc tggagccatt   1860

tggtatgagg tattaattta gcttaactaa attacagggg actcagaggc cgtgctcctg   1920

accgatccag acactattac tggctttttt tttttttttt taacaatggt gtgcatgtgc   1980

aggaaatgac aaatttgtat gtcagattat acaaggatgt attcttaaac cgcatgacta   2040

ttcagatggc tactgagtta tcagtggcca tttattagca tcatatttat ttgtattttc   2100

tcaacagatg ttaaggtaca actgtgtttt tctcgattat ctaaaaacca tagtacttaa   2160

attgaacagt tgcaaagatg tcttaattgt gtaaagaatt ggtgtagtca tgactttagc   2220

tgatactctt atgtacgaga tctgtctctg ctgtttaact tcattggatt aatcagctgg   2280

tttcaactct actgcgaaac aaaaatagct ccttaaaagt actgttctcc ttcagtggca   2340

tgtagttatc taatcaagac acctcattca aacaaaacct gccttaggaa aatttaatat   2400

attttaaatt attttaaaag aaatacaaca tcttattctt tagctttctt aatcggtgct   2460

ttatggaggc cagtgtaacg ttacatgact cgttgagaaa gttgaggaat ttcctctacc   2520

acctttgttg cttgaagaaa aacatgtctt ttcaaaatga gaggctttca ttgaagaaaa   2580

gaaaaaaaca acagttaaaa gcttttggct ctctgtttca tttttttcca ttaagaaaaa   2640

aaaaagtccc cttttaaaac aagcagggct gggtgtgacg gcacatgcct gtaatcccag   2700

cactttggga ggctgaggtg ggaggactgc ttgagcccag gagttcaaga tcagcctggg   2760

caacagagtg agataagacc caatctttat ttaaaaaata aataaataaa tagccaaaaa   2820

aaaaaaaaaa aaa                                                      2833


<210>  892
<211>  4795
<212>  DNA
<213>  Human

<400>  892
agagcggagc ctgtagccag gcgccatctt tgacgctggc agtcttggtt ttctgctagt     60

gctgctgctg ctgggaggac gacggacggc agcggccaag caagaagaaa gacgtggcag    120

caagcgggag tcggggatag tgtcatcggt tcgggtcccg gtactttgga gcttgtctca    180

aactccacat acagaaagcc accgacctta ttccggtatc ctacacccat tccccactct    240

cattacactc ccacccctgg ccctcagcgt cggagtcaag agcaacaggg acacttccgt    300

tctccttgta ggactggtga aaccgtaatg aagaacaccc ctaaactccc ataatcgatt    360

tggggatatt ccctgcccaa aaaattcctg gaaaattgac tagtattaag tgcgtaatag    420

attggaactc agtgaagaca cagatgttcc tgttcagagc aaccagctaa tgattacagt    480

ttaaagacaa tttctgtgat caagttgtca tttggaagat taaacccatt tcacgaggac    540

ttggagcctg gtccttgctt tgaggaagca gtggcttgtt tcaagaagcc acttctgatc    600

taagaatcta cccagcatgc ctaatcaagg agaagactgc tatttttttt tctattccac    660

atgtaccaaa ggcgacagct gcccattccg tcactgtgaa gctgcaatag gaaatgaaac    720

tgtttgcaca ttatggcaag aagggcgctg ttttcgacag gtgtgcaggt ttcggcacat    780

ggagattgat aaaaaacgca gtgaaattcc ttgttattgg gaaaatcagc caacaggatg    840

tcaaaaatta aactgcgctt tccatcacaa tagaggacga tatgttgatg gccttttcct    900

acctccgagc aaaactgtgt tgcccactgt gcctgagtca ccagaagagg aagtgaaggc    960

tagccaactt tcagttcagc agaacaaatt gtctgtccag tccaatcctt cccctcagct   1020

gcggagcgtt atgaaagtag aaagttccga aaatgttcct agccccacgc atccaccagt   1080

tgtaattaat gctgcagatg atgatgaaga tgatgatgat cagttttctg aggaaggtga   1140

tgaaaccaaa acacctaccc tgcaaccaac tcctgaagtt cacaatggat tacgagtgac   1200

ttctgtccgg aaacctgcag tcaatataaa gcaaggtgaa tgtttgaatt ttggaataaa   1260

aactcttgag gaaattaagt caaagaaaat gaaggaaaaa tctaagaagc aaggtgaggg   1320

ttcttcagga gtttccagtc ttttactcca ccctgagccc gttccaggtc ctgaaaaaga   1380

aaatgtcagg actgtggtga ggacagtaac tctctccacc aaacaaggag aagaaccctt   1440

ggttagattg agtcttactg agagactggg gaaacgaaaa ttttcagcag gcggtgacag   1500

tgatcctcca ttaaagcgta gcctggcaca gaggctaggg aagaaagttg aagctccaga   1560

aactaacatt gacaaaacac caaagaaagc tcaagtttcc aagtctctta aggagcgatt   1620

aggcatgtca gctgatccag ataatgagga tgcaacagat aaagttaata aagttggtga   1680

gatccatgtg aagacattag aagaaattct tcttgaaaga gccagtcaga aacgtggaga   1740

attgcaaact aaactcaaga cagaaggacc ttcaaaaact gatgattcta cttcaggagc   1800

aagaagctcc tccactatcc gtatcaaaac cttctctgag gtcctggctg aaaaaaaaca   1860

tcggcagcag gaagcagaga gacaaaaaag caaaaaggat acaacttgca tcaagctaaa   1920

gattgatagt gaaattaaaa aaacagtagt tttgccaccc attgttgcca gcagaggaca   1980

atcagaggag cctgcaggta aaacaaagtc tatgcaggag gtgcacatca agacgctgga   2040

agaaattaaa ctggagaagg cactgagggt gcagcagagc tctgagagca gcaccagctc   2100

cccgtctcaa cacgaggcca ctccaggggc aaggcggctg ctgcgaatca ccaaaagaac   2160

agggatgaaa gaagagaaga accttcagga aggaaatgaa gttgattctc agagcagtat   2220

tagaacagaa gctaaagagg cttcaggtga gaccacagga gttgacatca ctaaaattca   2280

agtcaagaga tgtgagacca tgagagagaa gcacatgcag aaacagcagg agagggaaaa   2340

atcagtcttg acacctcttc ggggagatgt agcctcttgc aatacccaag tggcagagaa   2400

accagtgctc actgctgtgc caggaatcac acggcacctg accaagcggc ttcccacaaa   2460

gtcatcccag aaggtggagg tagaaacctc agggattgga gactcattat tgaatgtgaa   2520

atgtgcagca cagaccttgg aaaaaagggg taaagctaaa cccaaagtga acgtgaagcc   2580

atctgtggtt aaagttgtgt catcccccaa attggcccca aaacgtaagg cagtggagat   2640

gcacgctgct gtcattgccg ctgtgaagcc actcagctcc agcagtgtcc tacaggaacc   2700

cccagccaaa aaggcagctg tggctgttgt cccgcttgtc tctgaggaca aatcagtcac   2760

tgtgcctgaa gcagaaaatc ctagagacag tcttgtgctg cctccaaccc agtcctcttc   2820

agattcctca cccccggagg tgtctggccc ttcctcatcc caaatgagca tgaaaactcg   2880

ccgactcagc tctgcctcaa caggaaagcc cccactctct gtggaggatg attttgagaa   2940

actaatatgg gagatttcag gaggcaaatt ggaagctgag attgacctgg atcctgggaa   3000

agatgaagat gaccttctgc ttgagctatc agaaatgatt gatagctgaa ggtggtagtg   3060

aggacacttt aaaaaaaaaa tcgccaaaaa actggactta gtttcatcta ttgtaacatt   3120

tacctgagat gatcatttct ttagtctaga atttgcccca aatcagaagt atacctctga   3180

attatctgta tgtgtcctgg attccttggg gtcagatttt taaagttact ttataaccat   3240

tttgtccatt tgatgccatt gtttatcatc ttttgagaaa aaagttctgt catacccttc   3300

tctccacaaa aaagagactg agagggagat caagtgaaag ggtgcaagcg aacttagtga   3360

ctccttgagg tgtttgtcag ttttggcttt tttcttcttt gttgtattct ttatgtattg   3420

tcttgatgta cttaatatta cctgagtttg aaatggatga agacagctgc taccattaag   3480

gaccaaattt tatgctacca ctaaacaaaa atacccactc agtctgtgtt aaattgtatg   3540

tctttttaaa ggtatttaaa gattcaacta agctttaaag agggctgagc agctcaggaa   3600

gcctgtaatg tgggcataac tctttggacc tgatcttgat gcttctgctg ctctgttagc   3660

ctctgaagag caatatctaa tttattatta ctgtaatttt ttaaaaggct ttaaagtgcc   3720

tcaggggtcc cctgaaacta attttctatt tctgggattc cctggattca ttatatgaga   3780

tggtgacatg attagaggaa ttctttttta gtatgaaaat tgtccctttt cttcttcagt   3840

acttgcctcc ttgctggcat tgaattaaca cagggacaaa atttggttaa ttttttattt   3900

ctaactctcc caacaaaccc ctgttgccca gtatttgttt ggtggccttt aaccacctga   3960

gggaaaaaat gagcttattc aagctgccaa tatttatcta tgggctgtag cagtacactg   4020

aattgtactg tgccagggat attgagatgc tctgggggtg tattgtatac ctgccagttt   4080

tcttcatttc tgaattgagt tttcttttct tgatgttggt ttccttcata tcacctcaag   4140

gtttagattt gtgaaggaat aagcatgatg gaaataatag tcttgaaagg agatatgttg   4200

tatataatca ggaggaagag gaaggaagga cttacccatt ttgatatttt gctgtaggtg   4260

gccagttttg tttctcatag ggaaatctga cccacctgtc atgttggctc ctaaggaact   4320

gctgttgtaa gcggctcatc aagagttgaa cttcacgtag ccttgttggg aatatggaaa   4380

aggaagaaag ccacaggact gcccattcag tcttgggaag attgggatga ttctgcacaa   4440

gcaaaaatga ctgaagttta tgtatagaca cacctctacc aatccatctt cagctgactg   4500

aatgttgtat gatagccctt ctccaaagca gaggtagaat gttcaggttt caccatggat   4560

tttctactta tttcgttttt ggaatcagct tacagattcc aggtcccttt tgtatatatt   4620

ctttattctt ttgctttttt aaaaaataat tttgtttcat atttaaagca cttgtattag   4680

tcaatgtttc gtgttccgca ttatttgaac catttgccct tacagaaaga gaaatacttg   4740

tttgtgtttt aaataaaact gatgtaggaa agtcttgaaa aaaaaaaaaa aaaaa        4795


<210>  893
<211>  2149
<212>  DNA
<213>  Human

<400>  893
ggcgcgcacg cgcagctccg cttccgggag ccgctcctcg ctacccacta tgctctgcga     60

catcgacctg tcgcaaaggc cgcgtttgcg gggccaatga gcgactcgct ttccgtgcgg    120

tgcggcgagt gaggccccgg tcttcctcct cgtcctgccg cagggccaga acccctgacg    180

gtattcagct gcgcgtaagt ctggccggtg ccatctgtct ccgcaatgcc ccccaagaaa    240

caggctcagg ccgggggcag caaaaaggcg gagcaaaaaa agaaggagaa gattatcgaa    300

gacaaaactt tcggtttgaa gaataagaaa ggagcaaagc aacagaagtt tatcaaggct    360

gtcacacatc aagttaaatt tggtcaacaa aatccacgtc aggtagcaca gagtgaagct    420

gaaaagaaat tgaagaagga tgacaagaag aaagaattgc aggagctaaa tgagctgttc    480

aaacctgtag ttgctgctca aaaaataagt aaaggtgcag atcccaagtc tgtagtatgt    540

gcattcttca agcaaggaca gtgtactaaa ggagataagt gtaagttctc ccatgacttg    600

actctggaga gaaaatgtga aaagcgaagt gtttacattg atgcaagaga tgaagaactt    660

gaaaaagata ctatggataa ttgggatgag aaaaagctgg aagaagtagt gaacaagaag    720

cacggtgagg cggaaaagaa aaaaccaaaa actcaaatag tgtgcaagca tttcctggaa    780

gctattgaaa acaacaagta tggctggttt tgggtatgcc ctggaggggg tgatatttgc    840

atgtatcgtc atgcacttcc tcctggattt gtgttgaaaa aagataaaaa gaaagaagag    900

aaagaagatg aaatttcatt agaagatcta attgagagag agcgttctgc cctaggtcca    960

aatgttacca aaatcactct agaatctttt cttgcctgga agaaaaggaa aagacaagaa   1020

aagattgata aacttgaaca agatatggaa agaaggaaag ctgacttcaa agcagggaaa   1080

gcactagtga tcagtggtcg tgaagtgttt gaatttcgtc ctgaactggt caatgatgat   1140

gatgaggaag cagatgatac ccgctacacc cagggaacag gtggtgatga ggttgatgat   1200

tcagtgagtg taaatgacat agatttaagc ctgtacatcc caagagatgt agatgaaaca   1260

ggtattactg tagccagtct tgaaagattc agcacatata cttcagataa agatgaaaac   1320

aaattaagtg aagcttctgg aggtagggct gaaaatggtg aaagaagtga cttggaagag   1380

gacaacgaga gggagggaac ggaaaatgga gccattgatg ctgttcctgt tgatgaaaat   1440

cttttcactg gagaggattt ggatgaacta gaagaagaat taaatacact tgatttagaa   1500

gaatgacacc aaacacatcg ctgaaaaaat taagtcagct cagcacgagt tgaaattgac   1560

tacattaatt tctttccacc tagaatcaac aggatgttta tttcctatgc tgattctgga   1620

ggagttaacc tcctgcaaaa aaggcatctt gtccctacat cttctcttct gactttggct   1680

acatctcata gtaagttcag agtagttcat gataaattga aaatataatg gtcattgcag   1740

aaaatgattg atgttgtaac tgtccaccca agtaagaagt gtatctgcct ttccatcttt   1800

tggttttcat ttgggcatgt gctattacca gaaacaacaa acttatattt aaaataccct   1860

tcatttgaca cagtttttaa tgagtgattt aatttcctct gtatttgtat gtttagaaga   1920

ctgcctaaaa catgagcact gtacttcata aaggaaactg cgtatgcaga ttcagtattg   1980

tgtatctttg gacaattaga tggacattta aaatggaact tcttttatct gacaggatca   2040

gctacaatgc cctgtgttaa attgtttaaa agtttccctt ttcttttttg ccaataaagt   2100

tgtaaataaa gaccatcata cattaaaatc caaaaaaaaa aaaaaaaaa               2149


<210>  894
<211>  4248
<212>  DNA
<213>  Human

<400>  894
cggaggctcc ccggtaggga cggcctgagg ccgagggcac cctgagggcg gaagaggcaa     60

agcgcctcgc ccgccggggc ctcggaggtg actaactcct agaggctgcg gcggagggga    120

gaagcctggt ggtacattcc atggcccagt gcctcggcca ctggaaaatc ccacaggggt    180

atatcgagta ggggaccgcg ggctccgcgg cagaaatgac cgcccttcca agatggcggc    240

tcccgtagag acactcccaa ggagacagcc atgttccttg cctgagagtc actgaaggaa    300

attggaaagc ccgcctctcc ttcgacgcac acgcgcacgc gcacgcacgc accggcgcgg    360

tcatccagca cagtgagcgg cccctgggca ccaccagaaa acatttgtga gtgaacgtgg    420

agtgatgacc atgtggacac tgtctttcca gggtttcttg gagcctctgc agagtctggg    480

ggccaggctt cttagtggaa actgcaggat cttccttctg acccctgctt gcctcgcccc    540

agcagctccg gttgagtcca cagatgccag ctcagcttcc agcttgggga agagtggggt    600

tgtcagcagg agagcctgag ggctgaggcc cagcgtgaac atggcagcta atggggactc    660

tcccccatgg tccccggccc tggctgcaga gggacgtggc agctcatgtg aggcttcagt    720

gtcatttgag gacgtgactg tggacttcag caaggaggag tggcagcact tggaccctgc    780

ccagagacgc ctgtactggg atgtgacact agagaactac agccacctgc tctcagtggg    840

gtaccaaatt cccaagtcag aggctgcctt caagttggag caaggagagg ggccatggat    900

gctggagggg gaagccccac atcagagctg ttcaggtgag gctattggga aaatgcagca    960

acagggaatt cctggaggaa ttttcttcca ctgtgagaga tttgatcaac ccataggaga   1020

agattcatta tgttctattt tagaagaact gtggcaagat aatgaccagc tagagcaacg   1080

tcaggaaaac cagaataacc ttttaagtca tgtgaaagta ttgattaagg agaggggcta   1140

tgaacataaa aacattgaaa aaataattca tgtgactacc aagcttgttc cttcaattaa   1200

aagactccat aactgtgaca caattttgaa gcatacttta aactcacata atcataatag   1260

aaacagtgca acaaagaacc ttggcaagat ttttggaaat ggtaacaatt tcccccatag   1320

cccttcctct actaagaatg agaatgctaa aacaggagca aattcctgtg aacatgacca   1380

ctatgaaaaa catctcagcc acaaacaagc tcccacccac catcagaaaa ttcatcctga   1440

ggagaagctt tatgtgtgta ctgaatgtgt aatgggcttc actcagaagt cacatctgtt   1500

tgagcatcag agaattcatg ctggagaaaa gtcccgtgaa tgtgacaaaa gcaacaaagt   1560

cttcccccag aaaccccagg ttgatgtaca tccaagtgtt tatacaggag aaaaacccta   1620

tctgtgtact caatgtggga aagtctttac cctcaaatca aacctcatta cacatcaaaa   1680

aattcatacc gggcagaaac cctacaaatg cagtgaatgt ggaaaagcct ttttccagag   1740

atcagacctc tttagacatc tgagaattca tacaggagaa aaaccttatg aatgcagtga   1800

atgtggaaaa ggcttctccc agaactcaga cctcagtata catcagaaaa ctcataccgg   1860

agagaaacac tatgaatgca atgaatgtgg gaaggctttc acaagaaaat cagcactcag   1920

gatgcatcag agaatccaca cgggagagaa accttatgta tgcgctgact gtgggaaggc   1980

cttcatccag aaatcacatt tcaacacaca tcagagaatt catactggag aaaagccgta   2040

tgaatgcagt gactgtggga aatccttcac taagaagtca caactccatg tgcatcaaag   2100

aattcacacc ggagagaaac cctatatatg tacagaatgt ggaaaggtct tcactcacag   2160

gacaaacctc accacacatc agaaaactca tactggggaa aaaccctata tgtgtgctga   2220

atgtggaaag gcttttactg accagtcaaa tctcattaaa caccagaaaa ctcacactgg   2280

agagaaaccc tataagtgca atggctgtgg aaaagccttc atatggaagt cgcgcctcaa   2340

aatacatcag aaatctcata ttggagagag acactatgaa tgcaaggact gcgggaaagc   2400

cttcatccag aaatcaacac taagcgtgca tcagagaatc catacaggag agaaaccgta   2460

cgtttgtcct gaatgcggga aggcctttat ccagaaatcg cacttcattg cgcatcatag   2520

aatccatact ggagagaagc cttatgaatg cagcgactgt gggaaatgct tcactaagaa   2580

gtcacaactc cgtgtgcatc agaaaatcca cacaggtgag aagcccaata tatgtgctga   2640

atgtggaaag gccttcactg accgatcaaa tctcataaca catcagaaaa tccacactag   2700

ggagaaaccc tatgaatgtg gtgactgcgg gaaaaccttc acctggaagt cacgcctcaa   2760

tatacatcag aagtctcata ctggagaaag acactatgaa tgtagtaaat gtgggaaagc   2820

tttcatccag aaagccacac taagtatgca tcagataatt catacaggaa agaaacctta   2880

tgcttgtaca gaatgtcaga aggcctttac tgacagatcg aatctcatta aacaccagaa   2940

aatgcatagt ggagaaaaac gctataaagc cagtgactga gaaagtcttc acctggaaat   3000

cacaactggg tatgcatcag gtatctaata gcagggagga ggaaggcctg ttgctgcaat   3060

cattgtacag ggggaaatgg gtatgagaga ctgaggcttg agtgaactga aggcaaacag   3120

agccaagtat ccttcagtcc actggaaaga caagttcctg catcaccaca gtgtatatgc   3180

aattctatgc ataggaagag cctttagaga aagcatttga gcgaaagtca tgtttggtga   3240

catgattcat acagacctct tgagctcctg gaaatagtag aattaagacc tgaggagatg   3300

actcgtcatc tcttatgctt cactttttgg ataaagaact ttttaaattc agtactgatt   3360

ggttcagcat atcctgggac ataaaaatac tcactactgg gaaaaacttt ttcaaatttc   3420

taggttgagg agaagagttt tcattgtcca aacactggca gggcactgac atcaaggcag   3480

aaaacctact tgggaatgca gatatctgtt tttgtgatca ttggcactta agacatagaa   3540

aagatttcca tgaaaaactt ttttcttttc ccttgggaag tcctcatggt atatatattt   3600

taagtgcaat ggaattttta aatttaaaga tataacttta tgaattgaga aattaggcct   3660

agctctaggc tatgttacag aaatatagtc attgaatgat acagacatat aaaggtagta   3720

gttgtctcat tattaattcc ctgctgggag agcagatgag tcatacccta taagaagtat   3780

gcatgccttc taacctatgt ccccaaagct gtcatttgca taagctgcag gccatagatt   3840

cctgattccc tcagtaactg accctacgac aatggaactg atccacggca ctctagattt   3900

tcaggctaac ccaccaacac ccctgctttc cttgggattt cctgaaaaag aatggttgaa   3960

aaattgagtt tcacttccta atattttgtt tttcttccta tttggttaag gtatattcat   4020

ttcctacatg cacattaagg gtagttttgt gtagactgct atgtgataaa gtcatgttgc   4080

attgcaatta gttattctaa gacataatta cagtttatca tagttgaata actggaagac   4140

ttctcaagaa agagcactgc tcttttttaa cactgatata tagacacgtt ctcattttcc   4200

cttaaacatt ttttacaata ctcataaaaa ggaactttct ttctagca                4248


<210>  895
<211>  3861
<212>  DNA
<213>  Human

<400>  895
tttgtctctc gccgcagcct gagctccagg tctccccttc gctgctctgt gtcctctgct     60

cctagaggcc caacatctgt ggccctgtga cctgcaggta ttgggagacc cacagctaag    120

acaccgggac cccctgaaag cctagaaatg gacgacttga aatatggagt gtatcctctc    180

aaggaagcaa gtggatgccc tggggctgag aggaatcttc tagtttactc ttattttgaa    240

aaggagacat tgacatttag ggatgtggcc atagaattct ctctggagga gtgggaatgc    300

ctgaaccctg ctcagcagaa tttatatatg aatgtgatgt tagaaaacta caaaaacctg    360

gtcttcttgg gtgttgctgt ctctaagcaa gacccagtca cctgtctgga gcaagaaaaa    420

gagccctgga atatgaagag acatgagatg gtggatgaac ccccagctat gtgttcttat    480

tttaccaaag acctttggcc agagcaagac ataaaagatt cttttcaaca agtaatactg    540

agaagatatg gcaaatgtga acatgagaat ttacagttaa gaaaaggctc cgcaagtgta    600

gatgagtata aggtgcacaa agaaggttat aatgagctaa accagtgttt gacaactacc    660

cagagcaaaa tatttccatg tgataaatat gtgaaagtct ttcataaatt tttaaatgca    720

aatagacata agacaagaca tactggaaag aaacctttca aatgtaaaaa atgtggcaaa    780

tcattttgca tgcttttaca cctaagtcaa cataaaagaa ttcatattag agagaattct    840

taccaatgtg aagaatgtgg caaagctttt aaatggttct caacccttac tagacacaag    900

agaattcata ctggagagaa acccttcaaa tgtgaagaat gtggcaaagc ttttaagcag    960

tcctcaaccc ttactacaca taagataatt catactgggg agaaaccata tagatgtgaa   1020

gaatgtggca aagccttcaa ccggtcctca caccttacta cacataagat aattcatact   1080

ggagagaagc cctacaaatg tgaagaatgt ggcaaagctt ttaaccagtc ttcaaccctt   1140

agtacacata agttcattca tgctggagag aaaccctaca aatgtgagga atgtgacaaa   1200

gcttttaatc gattctcata ccttactaaa cataagataa ttcatactgg agaaaaatct   1260

tacaaatgtg aagaatgtgg caaaggcttt aattggtcct caacccttac taaacataaa   1320

agaattcata ctggagagaa accctacaaa tgtgaagtgt gtggcaaagc ctttaatgag   1380

tcctcaaacc ttactacaca taagatgatt catactggag agaaacccta caaatgtgaa   1440

gaatgtggca aagcttttaa ccggtcccca caacttactg cacataagat aattcatact   1500

ggagagaaac cttacaaatg tgaagaatgt ggcaaagctt ttagccagtc atcaatcctt   1560

actacacata agagaattca cactggagag aaaccctaca aatgtgaaga atgtggcaaa   1620

gcttttaacc gatcctcaaa tcttactaaa cataagataa ttcatacagg agagaaatct   1680

tacaaatgtg aagaatgtgg taaagccttt aaccaatcct caactcttac taaacatagg   1740

aaaattcata ctagacagaa accctacaac tgtgaagaat gtgacaatac atttaaccag   1800

tcctcaaacc ttattaaaca aaataattca tactggagag aaactctaca aatgtcaaga   1860

atgtgggaaa gcctttaagc agtcctcaac tcttactaag cattaaatat tggccgggtg   1920

cggtggctta tgcaaaatgg ctcccagcat tttgggaggc tgaggtgggt ggatcacaag   1980

gtcaagagat cgagaccatc ctggccaaca tggtgaaacc ctgtctctac taaaaataca   2040

aaaattatct gggtgtggtg gcacgtgcct gtattcccat ctactcggga ggcttaggca   2100

ggataatcac ttgaacctgg gaggtggaag ttgcagtgag ccaagattgt accactgcac   2160

tccagtttgg caacagagtg agactccgtc tcaaaaaaaa tttatactgt acaaaaaccc   2220

cacaagtgtg aaaaacatgg caaagccttt aagaagccct caattcttaa cagacataag   2280

ataatttata ctggagagaa actctacaaa tcagaaagat gtgactactt ttgacaacgc   2340

ctcaaacttt tctaaccata aaagtaatta tactggtgag aaatcctaga aatctgaaga   2400

gtgagataaa gcctttaaat ggttgtcaca cttcattgta ggtaagataa ttcatactgg   2460

agaaaacgcc tacatgtgtg aacaatatgg caaaacttaa tgctcacact ttattgctag   2520

gaaagcattt atacttgaga taaattatac aaatataaag actgtgaaaa agccatcatt   2580

atctgctcac attttactca acacagagag ttcctgctta ataaaagcat tataagtgca   2640

attactgtca aaagatcttt cagaaaatat aagctttttt agtgaagagt atttattttg   2700

aagttgaaca tcacaaatat aaaaagggtt gtagtgcctt tacttgtatc acagatcttt   2760

ttgtagacat tttcttctag aggaaaactc tgaagcagtt gatcaaactt tgttcaacat   2820

cagggaattt atattgaaaa attgtgcaaa tataataaat ttggaaaaac aatttttcaa   2880

aaactacagc ttagaaatca acagttatac tagaatatat tttttccaga tgcagtaaaa   2940

gtaaaatatt taatccataa ttaagtctat gcaaatatca gagaatttat ggtagaaata   3000

tataaggtac tgacacttca gatatactaa atcagagtgc taagtataga aaatctgaaa   3060

ctaaagttgg tagaaaagtt atttgtatag aactttaaga ggatcagaag gttttttgca   3120

gagttataat tacattcaaa gtatacttta tttcttgaaa aatattacag attttttgaa   3180

aattgaataa tgtcatcatt caactctgaa attatttcct gttgtttctt cattcctatt   3240

ggattcacat gtgaaagcat ggggttaatt gttgctacat caaagagaga gattcttttg   3300

tttgtttgtt cgtttgtttt ttgagactga gtttcactct ttcgcccagg ctggagtgca   3360

ttggcatgat ctcagctcac tacaacctct gccttctggt ttcaagcaac tcttctgcct   3420

cagcatccca agtagctggg ataacaggtg ccagccacca tgcccagcta atttgtgtat   3480

ttctagtaga gatggggttt caccatattg gccaagctgg tcttgaactc ctgacctcat   3540

gtgatccgcc cgcctcagcc tcccaaagtg ctgggattac aggcttgagc caccacgccc   3600

agcctgtagc atattttaat aggagaatac aatatataat agtagcaggg ttaagtaagg   3660

catccatcat ctgtagcatt tctcctttgt tttacaaaca atccaattct acactttaaa   3720

aaaaaatttt taaatgtaca attaaatttt tatttaccac agtgttattt ttatcgtcat   3780

aataaaaatt atatacgagt ataaatgaaa ttcatttcta aattcttaat aaatattttc   3840

tcatgcaaaa aaaaaaaaaa a                                             3861


<210>  896
<211>  1839
<212>  DNA
<213>  Human

<400>  896
ttctaccgcg ggtgtacaca tggtttgcca gggtgtgcgc gtcttcccaa ggggtctggg     60

gaccaaattc cagctcccgc catcgggagg cacggtaaga gaccgtaggg gacacaatcc    120

cgagcaccgc agatgccgag gtctccgctg cgctccagtc tgtcaacaga ggcttcagga    180

ccgcggggtc ccttcaaatg ccccgccagt cccaggccaa tcaccgcgca gcttcttccg    240

ggatcgtcgc caatcatcgg ccgttgcgta ttgcgggtac agaggggtaa gtgaagcttc    300

gggcccttac atctttcttg aaggcaagaa gcctctcctc tacttcccag acaccccgcc    360

tcccccacta gaaaaagcag ccgaagcggc tttatttaag ggcaagtggg acgatgaggc    420

cagagaagtc agaaaggctc catatttgat atggtcaaat aatggcgccc ttaagagcag    480

cctgtgacaa ttgaagggtg gtcgccatat tttcagaagg caccttccgg gtcccttaac    540

ccgggtgtct atgtccaagc ggccatgaag tgaataaaca ctgaggaatt atatttgtcc    600

ctatcagaat cctcgaatcc ctagcagcca gtccctgcta cttcggttgc ctcggctgcg    660

ttcggacgcc acggctgggc ggggccgccc ttcctgtgga caacgacagc tgaggccggg    720

agcggggagg cggcggctcc agggacctgg cggccgccga tcggggctgc gaggccccat    780

ggcgccgccc ccagccccgc tcctggcgcc gaggcccggg gagacccggc ctggttgcag    840

gaagcccggg actgtgagct tcgcggacgt ggccgtgtac ttctccccgg aggagtgggg    900

ctgtctgcgg cccgcgcaga gggctctgta ccgggacgtg atgcaggaga cctacggcca    960

cctgggcgcg ctcggattcc caggccccaa accagccctc atctcttgga tggaacagga   1020

gagtgaggct tggagccccg ccgcccagga tcctgagaag ggggaaagac tgggaggagc   1080

tcggagagga gatgtcccaa acaggaagga agaggaaccg gaggaagtcc caagagccaa   1140

agggcctaga aaggctcctg tgaaggagag tcctgaagtg ctggtggaac gcaaccctga   1200

cccagctatt agcgtggccc cggcacgggc acagccaccc aaaaatgctg cctgggaccc   1260

gaccacagga gcacagcccc cggcacccat acccagcatg gatgctcagg ccggccagcg   1320

gcgccacgtg tgcacggact gcggccgccg cttcacctac ccctcactgc tggtcagcca   1380

caggcgcatg cactcggggg agcggccttt cccctgcccc gagtgtggca tgcgcttcaa   1440

gaggaagttc gcagtggaag cgcaccagtg gatccaccgc tcctgctccg gggggcggcg   1500

gggccggagg cctgggatcc gggctgtgcc tcgggccccc gtccgaggtg accgggaccc   1560

gcctgtgctc ttccggcact acccagacat cttcgaggag tgcggctgag cggcaccgca   1620

ggctggagtt gagcctgacc ttggcacgaa ggactgacgg atccctgagg tgggccactg   1680

agtcggggac tccggaactg aaattcatgc cctgggcttt cctcaaggat ccctcaagtt   1740

tccaacttgt aaaaagaaaa gtgcctgtaa agattcgaat agattagact tgccacccat   1800

ctccccagtc ttttgtttaa caaaaaaaaa aaaaaaaaa                          1839


<210>  897
<211>  2547
<212>  DNA
<213>  Homo sapiens

<400>  897
tggttgcgtc gggtcacgtg ggcgcgcagg cgcagcgcgg tgcagcccgt tcgctcacac     60

aaagcccaga cgcggagaaa atggcggcag gggtcgaagc ggcggcggag gtggcggcga    120

cggagatcaa aatggaggaa gagagcggcg cgcccggcgt gccgagcggc aacggggctc    180

cgggccctaa gggtgaagga gaacgacctg ctcagaatga gaagaggaag gagaaaaaca    240

taaaaagagg aggcaatcgc tttgagccat atgccaatcc aactaaaaga tacagagcct    300

tcattacaaa catacctttt gatgtgaaat ggcagtcact taaagacctg gttaaagaaa    360

aagttggtga ggtaacatac gtggagctct taatggacgc tgaaggaaag tcaaggggat    420

gtgctgttgt tgaattcaag atggaagaga gcatgaaaaa agctgcggaa gtcctaaaca    480

agcatagtct gagcggaaga ccactgaaag tcaaagaaga tcctgatggt gaacatgcca    540

ggagagcaat gcaaaaggtg atggctacga ctggtgggat gggtatggga ccaggtggcc    600

caggaatgat tactatccca cccagtatcc taaataatcc caacatccca aatgagatta    660

tccatgcatt acaggctgga agacttggaa gcacagtatt tgtagcaaat ctggattata    720

aagttggctg gaagaaactg aaggaagtat ttagtatggc tggtgtggtg gtccgagcag    780

acattcttga agataaagat ggaaaaagtc gtggaatagg cactgttact tttgaacagt    840

ccattgaagc tgtgcaagct atatctatgt tcaatggcca gctgctattt gatagaccaa    900

tgcacgtcaa gatggatgag agggccttac caaaaggaga tttcttccct cctgagcgtc    960

cacaacaact tccccatggc cttggtggta ttggcatggg gttaggacca ggagggcaac   1020

ccattgatgc caatcacctg aataaaggca tcggaatggg aaacataggt cccgcaggaa   1080

tgggaatgga aggcatagga tttggaataa ataaaatggg aggaatggag gggccctttg   1140

gtggtggtat ggaaaacatg ggtcgatttg gatctgggat gaacatgggc aggataaatg   1200

aaatcctaag taatgcactg aagagaggag agatcattgc aaagcaggga ggaggtggag   1260

gtggaggaag cgtccctggg atcgagagga tgggtcctgg cattgaccgc ctcgggggtg   1320

ccggcatgga gcgcatgggc gcgggcctgg gccacggcat ggatcgcgtg ggctccgaga   1380

tcgagcgcat gggcctggtc atggaccgca tgggctccgt ggagcgcatg ggctccggca   1440

ttgagcgcat gggcccgctg ggcctcgacc acatggcctc cagcattgag cgcatgggcc   1500

agaccatgga gcgcattggc tctggcgtgg agcgcatggg tgccggcatg ggcttcggcc   1560

ttgagcgcat ggccgctccc atcgaccgtg tgggccagac cattgagcgc atgggctctg   1620

gcgtggagcg catgggccct gccatcgagc gcatgggcct gagcatggag cgcatggtgc   1680

ccgcaggtat gggagctggc ctggagcgca tgggccccgt gatggatcgc atggccaccg   1740

gcctggagcg catgggcgcc aacaatctgg agcggatggg cctggagcgc atgggcgcca   1800

acagcctcga gcgcatgggc ctggagcgca tgggtgccaa cagcctcgag cgcatgggcc   1860

ctgccatggg cccggccctg ggcgctggca ttgagcgcat gggcctggcc atgggtggcg   1920

gtggcggtgc cagctttgac cgtgccatcg agatggagcg tggcaacttc ggaggaagct   1980

tcgcaggttc ctttggtgga gctggaggcc atgctcctgg ggtggccagg aaggcctgcc   2040

agatatttgt gagaaatctg ccattcgatt tcacatggaa gatgctaaag gacaaattca   2100

acgagtgcgg ccacgtgctg tacgccgaca tcaagatgga gaatgggaag tccaaggggt   2160

gtggcgtggt taagttcgag tcgccagagg tggccgagag agcctgccgg atgatgaatg   2220

gcatgaagct gagtggccga gagattgacg ttcgaattga tagaaacgct taagcagttg   2280

ccttttttaa acatcgatac gagacctctg aatttgtatt ttttcttgtt aaccatttta   2340

atttgttggc tggatgtata aagatgttta aaaaattcag ttgctttttg gggtaatttg   2400

aattactttt ttaatgactg gggttccatt tgactgtttg cattgagatt gcaatgtgcg   2460

caattttttt tgtagttgtg gcatcttgtt gacatcgaat atgactttga taataaatac   2520

cggttcctga aaacggcaaa aaaaaaa                                       2547


<210>  898
<211>  2128
<212>  DNA
<213>  Homo sapiens

<400>  898
aatcctaggc ggcgtcccct ggccattacc tcattccctg gcctcgttct ccccaatccc     60

ggcctctcca ggggtgtggc agcagggctg ttctcgcgac ttttgcttta cccttctgct    120

gtgctactgc tgtcgcgaga cttcctgctc atctgccgct ccctttgccg ccgccttagc    180

ccgggacccg aacccagcct ctcccctacc cgaacaccgg ccccggctcc accgaggccc    240

gggtccccca gcccgtctcg ccgccgccat ggcggaccct aaatacgccg accttcccgg    300

cattgccagg aatgagccag atgtttatga aactagcgac ctacctgagg atgatcaagc    360

ggagttcgat gcgtttgcac aagagctgga ggagctgaca agcacaagtg tggaacacat    420

cattgtcaat cctaatgctg cctatgacaa gttcaaggac aagagagtgg ggacaaaggg    480

acttgatttc tcagatcgta ttggaaaaac caagaggaca ggatatgaat ctggagaata    540

tgagatgctt ggagagggtc tgggagtgaa ggagacaccc cagcaaaagt accagcgcct    600

actgcatgag gtccaagagc tgacaactga agttgaaaaa atcaagacga cagtgaagga    660

gtcagccaca gaggagaagc tgacccctgt gttgctggct aaacagctgg cagccctgaa    720

gcagcagctg gttgcttccc acctggagaa gctgctggga ccagatgctg caatcaacct    780

taccgacccc gatggcgccc tggctaagcg cctactactg cagctggaag caacaaagaa    840

cagcaaaggg ggatcagggg gaaaaaccac tgggaccccc ccagatagca gccttgtcac    900

ttatgaacta cattctcggc ctgagcagga caagttctct caagctgcca aagtcgcaga    960

acttgaaaag cgcctgacag agctggagac agctgtacgt tgtgatcagg atgctcagaa   1020

tcccctttct gcaggtctac agggagcctg tctcatggag actgtagagc tgttgcaagc   1080

aaaggtgagc gccctagacc ttgcagtttt ggatcaagtg gaggctcggc tacagagtgt   1140

cctgggaaag gtgaacgaga ttgccaagca taaagcctct gtagaagatg cagatacaca   1200

aagcaaggtg caccagctat atgaaactat acagcgctgg agccccattg cctccaccct   1260

ccctgagctg gtgcagagac ttgtcaccat caagcagctg cacgagcaag ccatgcagtt   1320

tggtcagctc ctgacacact tggataccac ccagcagatg attgctaatt ccttgaagga   1380

caataccacc ctcttgaccc aggtgcagac aaccatgcgt gaaaacctgg ccacagttga   1440

ggggaacttt gccagcattg atgaacggat gaagaagctg ggaaagtgag cacatttggg   1500

agctggagaa caggggttat ccctacccct gtgaactctg ttaacagctt acatagggtt   1560

tcccctttac tataactcta gcatccccat cccatttgac actgggggca agggttcttc   1620

ttgcatgtgg ggtttatacc cctcccctga tgaatacaga gtggtagcta ggggttggtt   1680

atcatcagaa ggtggtctcc cctcaggcct gggggataag gacgtgggcc cagccacatg   1740

ccaactcatg tccaatactg ctttgcctgg tgtggggaag gattgggtct tgtcccccaa   1800

cacagcttct gtggctgact gtaatactgt acaactgttt ctgaccatta aatgctgttg   1860

tactctgtgt ggcctctgct gtgtttcctg gggaggaagc agcactagga tatagatatt   1920

cattcgtcat aacaggcaat ctaagccact ctatactaca agagatggat ttaaattgta   1980

acctgttctt accaaagaac taaataaaaa atgagtacag agccagagcc agagtttcaa   2040

aatattctca tctgttaaat taagagtgtc tcccatagaa aagcagtgga ggccccacag   2100

ggcaagtaca aaacagaatt aaaactcc                                      2128


<210>  899
<211>  3533
<212>  DNA
<213>  Homo sapiens

<400>  899
aggggaagac gtggcaccag tcggaggggc ggggctggga ggggctcctc cctaccgccc     60

ccaattccgc cctgcccccg ccgcggcggc gctagccgcc actgagggac cgaccctata    120

aaggccgctc cgcgaggggt gcgcagcatt cggcagaggg cgcttcgacg ggctgggctg    180

tgcgcctgcg cagtgtgggt cgctcccgat tccctgcccc ggccggcccc gcctcggctc    240

cgcaccctcg ccccgctctc agccgccgct ctgccccgca gcagccagcc ccgtgtccgg    300

cagtatgttc agctgggtca gcaaggatgc ccgccgcaag aaggagccgg agctcttcca    360

gacggtggcc gaggggctgc ggcagctgta cgcgcagaag ctgctacccc tggaggagca    420

ctaccgcttc cacgagttcc actcgcccgc gctggaggac gctgacttcg acaacaagcc    480

tatggtgctc ctcgtggggc agtacagcac gggcaagacc accttcatcc gacacctgat    540

cgagcaggac ttcccgggga tgcgcatcgg gcccgagccc accaccgact ccttcatcgc    600

cgtcatgcac ggccccactg agggcgtggt gccgggcaac gcgctcgtgg tggacccgcg    660

gcgccccttc cgcaagctca acgcgtttgg caacgctttc ctcaacaggt tcatgtgtgc    720

ccagctgccc aaccccgtcc tggacagcat cagcatcatc gacacccccg ggatcctgtc    780

tggagagaag cagcggatca gcagaggcta tgactttgca gccgtcctgg agtggttcgc    840

ggagcgtgtg gaccgcatca tcctgctctt cgacgcccac aagctggaca tctccgatga    900

gttctcggaa gtgatcaagg ctctgaagaa ccatgaggac aagatccgcg tggtgctgaa    960

caaggcagac cagatcgaga cgcagcagct gatgcgggtg tacggggccc tcatgtggtc   1020

cctgggcaag atcatcaaca cccccgaggt ggtcagggtc tacatcggct ccttctggtc   1080

ccacccgctc ctcatccccg acaaccgcaa gctctttgag gccgaggagc aggacctctt   1140

caaggacatc cagtcactgc cccgaaacgc cgccctcagg aagctcaatg acctgatcaa   1200

gcgggcacgg ctggccaagg ttcacgccta catcatcagc tccctcaaga aagagatgcc   1260

caatgtcttt ggtaaagaga gcaaaaagaa agagctggtg aacaacctgg gagagatcta   1320

ccagaagatt gagcgcgagc accagatctc ccctggggac ttcccgagcc tccgcaagat   1380

gcaggaactc ctgcagaccc aggacttcag caagttccag gcgctgaagc ccaagctgct   1440

ggacacggtg gatgacatgc tggccaacga catcgcgcgg ctgatggtga tggtgcggca   1500

ggaggagtcc ctgatgcctt cccaggtggt caagggcggc gcctttgacg gcaccatgaa   1560

cgggccgttc gggcacggct acggcgaggg ggccggcgag ggcatcgacg acgtggagtg   1620

ggtggtgggc aaggacaagc ccacctacga cgagatcttc tacacgctgt cccctgtcaa   1680

cggcaagatc acgggcgcca acgccaagaa ggagatggtg aagtccaagc tccccaacac   1740

cgtgctaggg aagatctgga agctggccga cgtggacaag gacgggctgc tggacgacga   1800

ggagttcgcg ctggccaacc acctcatcaa ggtcaagctg gagggccacg agctgcccgc   1860

cgacctgccc ccgcacctgg tgccgccctc caagcgcaga catgagtgat ggcgcccggc   1920

cccgcacctg ccatttgcac gcccggccgg gaggcagaga cggggggagg ggaagcctca   1980

ccatttctca aggtccataa agactgagcg gatgtttcct cgcctctcga aaaggaaaac   2040

caccatcttt cttttaaggc tgttcctggg cctggcgggg gaggcagggg tgagaggatg   2100

gaattgtgtg cacaagaact gtggctattt taatatataa cgttagaggc tgcgttcttt   2160

gtcgccgcct cccctgtgtg ccagccctgt gtgcacggcc tctgcccccc ggcctttgct   2220

gtggctggag ctggacagtg cagcgactgc gaccgtgggg gagccaggtc gcccttttgg   2280

cagctgctag gctgaggctg catggacagg aacaccaggc accctccgtg tgcttctgag   2340

ctgaggttgc ttcacgggac cgtggcttcc ttcctcacct ggctctgcct cccccgtgct   2400

ctcgggcgaa gtgggttctt gtgccttccc ctcccgggcc caggctcccc gtgcgcgggc   2460

cctgcccttt cctcccgcgc cccaccggct ccgacgcgca accccgctca gcagtcacag   2520

aagcagggcc cagccacctt ggtctttttt tgggagttca ggggagtagg agaatgtctt   2580

ccagaaaaat acataagcta gtttctgttc tgtaaagtga tatctttcat acttgaccaa   2640

agttcccaat aacttcccaa ccactgttca aaagctgtga tttttgtctc cccttcccac   2700

cctccagcca aggagcagcc ctgcccaggg ggcattaggt gtgggtaccc ggggagcacc   2760

ccgttcctgg accccagtgt tgcatttcct ggctgaggaa gggtggtcat cccagctcct   2820

gccctaccct ctcacttaac tggagctttg ggacgcaccc tccacagtgg gaggtggtgg   2880

tgggtggcgg tggcggggcc tcacgacagc ttggtgctgg taagaggaag cccgtggttc   2940

tggctaggct ctcatgtcca gacagcgggg accaggggaa aacccagccc cttctgtaat   3000

cccccttcat ttcctacctt ccttcctcct ctgtttagca aaggagggca gctcacttgg   3060

atgtccttac aacgcccctg gcccccaggt tgagcaataa gaaaccagaa ccttgcggcc   3120

cagtggcccg ggccagttca ggccgcctcc ccctcctctg cctggggcca ttgagcccag   3180

cctccagggc ccgggcgcgt ttgcaggcca gtggccactg tccgggctgt gatggcacca   3240

aggcaggtgg agcaccaggt accacacagc tgggcttccc accaggcttt cccgcggggg   3300

tctcagggag cttctcccca gcgctgctcg gagtctgcag gaactggcct tgttctcctt   3360

agcccgtcac tccatacagt attaggtgag gatggatgcg ggcgctgtcc ttgccgggaa   3420

gtcactgttg aagttgcagt ggcttgttca cacctgtggg aagagaagtg aagactttct   3480

ccttgcatta aaaagtctga actgtgcgaa agcttaaaaa aaaaaaaaaa aaa          3533


<210>  900
<211>  2149
<212>  DNA
<213>  Homo sapiens

<400>  900
ggccgctagg ggtgcggggt tggggaggag gccgctagtc tacgcctgtg gagccgatac     60

tcagccctct gcgaccatgg ctgtgctggc ggcacttctg cgcagcggcg cccgcagccg    120

cagccccctg ctccggaggc tggtgcagga aataagatat gtggaacgga gttatgtatc    180

aaaacccact ttgaaggaag tggtcatagt aagtgctaca agaacaccca ttggatcttt    240

tttaggcagc ctttccttgc tgccagccac taagcttggt tccattgcaa ttcagggagc    300

cattgaaaag gcagggattc caaaagaaga agtgaaagaa gcatacatgg gtaatgttct    360

acaaggaggt gaaggacaag ctcctacaag gcaggcagta ttgggtgcag gcttacctat    420

ttctactcca tgtaccacca taaacaaagt ttgtgcttca ggaatgaaag ccatcatgat    480

ggcctctcaa agtcttatgt gtggacatca ggatgtgatg gtggcaggtg ggatggagag    540

catgtccaat gttccatatg taatgaacag aggatcaaca ccatatggtg gggtaaagct    600

tgaagatttg attgtaaaag acgggctaac tgatgtctac aataaaattc atatgggcag    660

ctgtgctgag aatacagcaa agaagctgaa tattgcacga aatgaacagg acgcttatgc    720

tattaattct tataccagaa gtaaagcagc atgggaagct gggaaatttg gaaatgaagt    780

tattcctgtc acagttacag taaaaggtca accagatgta gtggtgaaag aagatgaaga    840

atataaacgt gttgatttta gcaaagttcc aaagctgaag acagttttcc agaaagaaaa    900

tggcacagta acagctgcca atgccagtac actgaatgat ggagcagctg ctctggttct    960

catgacggca gatgcagcga agaggctcaa tgttacacca ctggcaagaa tagtagcatt   1020

tgctgacgct gctgtagaac ctattgattt tccaattgct cctgtatatg ctgcatctat   1080

ggttcttaaa gatgtgggat tgaaaaaaga agatattgca atgtgggaag taaatgaagc   1140

ctttagtctg gttgtactag caaacattaa aatgttggag attgatcccc aaaaagtgaa   1200

tatcaatgga ggagctgttt ctctgggaca tccaattggg atgtctggag ccaggattgt   1260

tggtcatttg actcatgcct tgaagcaagg agaatacggt cttgccagta tttgcaatgg   1320

aggaggaggt gcttctgcca tgctaattca gaagctgtag acaacctctg ctatttaagg   1380

agacaaccct atgtgaccag aaggcctgct gtaatcagtg tgactactgt gggtcagctt   1440

atattcagat aagctgtttc attttttatt attttctatg ttaactttta aaaatcaaaa   1500

tgatgaaatc ccaaaacatt ttgaaattaa aaataaattt cttcttctgc ttttttcttg   1560

gtaaccttga aaagtttgat acatttttgc attctgagtc tatacttatc gaaatatggt   1620

agaaatacca atgtgtaata ttagtgactt acataagtag ctagaagttt ccatttgtga   1680

gaacacattt atatttttga ggattgttaa aggtcaagtg aatgctcttt ataggtaatt   1740

tacatttagt aaattacggt aaattaaatt acttctcttt acagtaagag ttggctattc   1800

tggacaaact agcagtgctt catataatca ctcaaaccac agtgtgtgca gcagtactag   1860

aaacaagaca gaagcccatg tcctcagggt ctagagtggg ggcaatttct tataacctca   1920

acattcaggg ttgggggagg tcaagcagaa aaccctggag tttgggctct gaattactat   1980

agcagcatag agagtgggaa gggaggtaga aactgatatg ctgaatggat atataaaaaa   2040

gggaacagat caccacttcc aatacacgac aatgcctgtt cttaagcagg acagactgta   2100

acagaagtat ctcgcattgc attttatctg ggaaaaaaaa aaaaaaaaa               2149


<210>  901
<211>  1048
<212>  DNA
<213>  Homo sapiens

<400>  901
ataaaggggt ggcccgtaga agattccagc accctcccct aactccaggc cagactcctt     60

tcagctaaag gggagatctg gatggcatct acttcgtatg actattgcag agtgcccatg    120

gaagacgggg ataagcgctg taagcttctg ctggggatag gaattctggt gctcctgatc    180

atcgtgattc tgggggtgcc cttgattatc ttcaccatca aggccaacag cgaggcctgc    240

cgggacggcc ttcgggcagt gatggagtgt cgcaatgtca cccatctcct gcaacaagag    300

ctgaccgagg cccagaaggg ctttcaggat gtggaggccc aggccgccac ctgcaaccac    360

actgtgatgg ccctaatggc ttccctggat gcagagaagg cccaaggaca aaagaaagtg    420

gaggagcttg agggagagat cactacatta aaccataagc ttcaggacgc gtctgcagag    480

gtggagcgac tgagaagaga aaaccaggtc ttaagcgtga gaatcgcgga caagaagtac    540

taccccagct cccaggactc cagctccgct gcggcgcccc agctgctgat tgtgctgctg    600

ggcctcagcg ctctgctgca gtgagatccc aggaagctgg cacatcttgg aaggtccgtc    660

ctgctcggct tttcgcttga acattccctt gatctcatca gttctgagcg ggtcatgggg    720

caacacggtt agcggggaga gcacggggta gccggagaag ggcctctgga gcaggtctgg    780

aggggccatg gggaagtcct gggtgtgggg acacagtcgg gttgacccag ggctgtctcc    840

ctccagagcc tccctccgga caatgagtcc cccctcttgt ctcccaccct gagattgggc    900

atggggtgcg gtgtgggggg catgtgctgc ctgttgttat gggttttttt tgcggggggg    960

gttgcttttt tctggggtct ttgagctcca aaaaataaac acttcctttg agggagagca   1020

cacctgaaaa aaaaaaaaaa aaaaaaaa                                      1048


<210>  902
<211>  1352
<212>  DNA
<213>  Homo sapiens

<400>  902
cgtgaagtgg gcggagcgag cgatttgaac gcgagcggcg cggacttctg ccaagcaccg     60

gctcatgtga ggctcgcggc acagcgttct ctgggctccc cagaagccag cctttcgctc    120

ccggacccgg cagcccgagc aggagccgtg ggaccgggcg ccagcaccct ctgcggcgtg    180

tcatgggccc gcgccgccgg agccgaaagc ccgaggcccc gaggaggcgc agcccgagcc    240

cgaccccgac ccccggcccc tcccggcggg gcccctcctt aggcgcttcc tcccatcaac    300

acagtcggcg gagacaaggt tggctaaagg agatccgaaa gcttcagaag agcacacacc    360

tcttgataag gaagctgccc ttcagccgcc tggcagcaga agcatttcta gttcatctct    420

ttgaggacgc ctatctcctc accttacatg caggccgagt tactctcttc ccaaaggatg    480

tgcaactggc ccggaggatc cggggccttg aggagggact cggctgagct cctgcaccca    540

gtgtttctgt cagtctttcc tgctcagcca ggggggatga taccggggac tctccagagc    600

catgactaga tccaatggat tctgcgatgc tgtctggact ttgctgtctc tgaacagtat    660

gtgtgtgttg ctttaaatat ttttcttttt tttgagaagg agaagactgc atgactttcc    720

tctgtaacag aggtaatata tgagacaatc aacaccgttc caaaggcctg aaaataattt    780

tcagataaag agactccaag gttgacttta gtttgtgagt tactcatgtg actatttgag    840

gattttgaaa acatcagatt tgctgtggta tgggagaaaa ggctatgtac ttattatttt    900

agctctttct gtaatattta cattttttac catatgtaca tttgtacttt tattttacac    960

ataagggaaa aaataagacc actttgagca gttgcctgga aggctgggca tttccatcat   1020

atagacctct gcccttcaga gtagcctcac cattagtggc agcatcatgt aactgagtgg   1080

actgtgcttg tcaacggatg tgtagctttt cagaaactta attggggatg aatagaaaac   1140

ctgtaagctt tgatgttctg gttacttcta gtaaattcct gtcaaaatca attcagaaat   1200

tctaacttgg agaatttaac attttactct tgtaaatcat agaagatgta tcataacagt   1260

tcagaatttt aaagtacatt ttcgatgctt ttatgggtat ttttgtagtt tctttgtaga   1320

gagataataa aaatcaaaat atttaatgaa aa                                 1352


<210>  903
<211>  3019
<212>  DNA
<213>  Homo sapiens

<400>  903
cccagccctc gtcgccgccg ccattttagc tgttggttcc ggccgcaccg tgtgggctgt     60

agtagcggga ggggtggggg tcctccagag ttaagtggct gtcctcgact gtgcccatac    120

agcagccagc tttcttcctt aataactgcc cgttcgaaga gtgcgaggat gtccaagcgg    180

caccggttgg acctagggga ggattacccc tctggcaaga agcgtgcggg gaccgatggg    240

aaggatcgag atcgagaccg ggatcgtgaa gatcggtcta aagatcgaga ccgagaacgt    300

gatagaggag atagagagcg agagagggag aaagaaaagg agaaggagtt gcgagcttca    360

acaaatgcta tgcttatcag tgctggatta ccacctttga aagcttccca ttcagctcac    420

tcaacccact cagcacattc aacgcattca acacattctg ctcattcaac gcatgccgga    480

catgcaggtc acacgtcact tccacagtgc attaatccgt tcaccaactt accccatact    540

cctcgatact atgatattct aaagaaacgt cttcagctcc ctgtttggga atacaaggat    600

aggtttacag atattctggt tagacatcag tcctttgtac tggttggtga gactgggtct    660

ggtaaaacaa cacagattcc acagtggtgt gtggagtaca tgcgatcatt accaggaccc    720

aagagaggag ttgcctgtac ccaacccagg agagtggctg caatgagtgt ggctcagaga    780

gttgctgatg agatggatgt gatgttgggc caggaagttg gttactccat tcgatttgaa    840

gactgcagta gtgcaaaaac cattcttaag tatatgactg atgggatgtt acttcgtgaa    900

gctatgaatg atcccctcct ggagcgttat ggtgtaataa ttcttgatga ggctcatgag    960

aggacactgg ctacagatat tctaatgggt gttctgaagg aagttgtaag acagagatca   1020

gatttaaagg ttatagttat gagcgctact ctagatgcag gaaaattcca gatttacttt   1080

gataactgtc ctctcctaac tattcctggg cgtacacatc ctgttgagat cttctatact   1140

ccagaaccag agagagatta tcttgaagca gcaattcgaa cagttatcca gattcatatg   1200

tgtgaagagg aagagggaga tcttcttctt ttcttaactg gtcaagagga aattgatgaa   1260

gcctgtaaga gaataaagcg tgaagttgat gatttgggcc ctgaagttgg tgacattaaa   1320

atcattccat tgtattctac acttccacct cagcagcagc aacgcatttt tgagcctcca   1380

cctcccaaaa aacagaatgg agcaattgga agaaaggtag ttgtgtcaac taacatagca   1440

gagacgtctt tgacaataga tggtgtggtg tttgtgattg atcctggatt tgcgaaacag   1500

aaggtctaca atcctcgaat cagagttgag tcccttttgg tgacagctat tagtaaagct   1560

tcagctcagc aaagggctgg tcgagctgga cgtaccagac ctggaaaatg cttcagactt   1620

tacacagaga aagcttataa aacagaaatg caggataaca cctatcctga gattttgcgt   1680

tctaatttag gatcagttgt gttacaattg aagaaacttg gtattgatga cttggtacat   1740

tttgatttta tggatccacc agctcctgaa actctgatga gagccctgga acttttgaat   1800

tacctggctg ctttaaatga tgatggagat ctgactgaat tgggatccat gatggcagag   1860

tttcctctag atccacagct cgcaaaaatg gttattgcaa gttgtgacta caactgttct   1920

aatgaggtcc tatctattac tgctatgttg tcagtcccac agtgttttgt tcgccccacg   1980

gaggccaaga aagccgcaga tgaggccaag atgagatttg cccacataga tggagatcat   2040

ctgacactgc tgaacgtcta ccatgctttt aaacaaaatc atgaatcggt tcagtggtgt   2100

tatgacaact tcattaacta caggtccctg atgtccgcag acaatgtacg ccagcagcta   2160

tctcgaatta tggacagatt taatttgcct cgtcgaagta ctgactttac aagcagggac   2220

tattatatta atataagaaa agctttggtt actgggtatt ttatgcaggt ggcacattta   2280

gaacgaacag ggcattactt aactgtgaaa gataaccagg tggttcagtt gcatccctct   2340

actgttcttg accacaaacc tgaatgggtg ctttataatg agtttgttct aacaacaaag   2400

aattacatcc ggacatgtac agatatcaag ccagaatggt tggtgaaaat tgcccctcaa   2460

tattatgaca tgagcaattt cccacagtgt gaagcaaaga gacagttgga ccgcatcatt   2520

gccaaacttc aatccaagga atattcacag tactgaattc agtgcttaga actgaagtta   2580

ttgagaggac agctttaaaa gatgaatgaa ctcaaaagtt cgagttgtgc tcttcacgtt   2640

ggttcgataa tggcctttat ttgaaagctt tttaattttt ctttacagta aatattccat   2700

tctgatttca taaattaaac atttatgcct cccttttgtg ttgacactgt agctcatact   2760

ggaaaagtcg atcaatgttt tgcagtttat tgaaagtagt tctatatata acaatgttat   2820

aagcatttct ttagaaatgg ttgaaaatgc ttctaaaatg tgattatcga ccatggtatg   2880

catgatcgtt gtaattgttg acattccttt tagaagttgt gaaatgttac aacttgtgct   2940

tatgtagaca caatcttctg tctcagtaca gaggcactga cttcaataaa gtctatttat   3000

actaattttg gccaaaaaa                                                3019


<210>  904
<211>  8056
<212>  DNA
<213>  Homo sapiens

<400>  904
cgtggggatc ccggggcagc cgagggcccc tgactcggct cctcgcggcg acatggatcg     60

gatggccagc tccatgaagc aggtgcccaa cccactgccc aaggtgctga gccggcgcgg    120

ggtcggcgct gggctggagg cggcggagcg cgagagcttc gagcggactc agactgtcag    180

catcaataag gccattaata cgcaggaagt ggctgtaaag gaaaaacacg ccagaacgtg    240

catactgggc acccaccatg agaaaggggc acagaccttc tggtctgttg tcaaccgcct    300

gcctctgtct agcaacgcag tgctctgctg gaagttctgc catgtgttcc acaaactcct    360

ccgagatgga cacccgaacg tcctgaagga ctctctgaga tacagaaatg aattgagtga    420

catgagcagg atgtggggcc acctgagcga ggggtatggc cagctgtgca gcatctacct    480

gaaactgcta agaaccaaga tggagtacca caccaaaaat cccaggttcc caggcaacct    540

gcagatgagt gaccgccagc tggacgaggc tggagaaagt gacgtgaaca actttttcca    600

gttaacagtg gagatgtttg actacctgga gtgtgaactc aacctcttcc aaacagtatt    660

caactccctg gacatgtccc gctctgtgtc cgtgacggca gcagggcagt gccgcctcgc    720

cccgctgatc caggtcatct tggactgcag ccacctttat gactacactg tcaagcttct    780

cttcaaactc cactcctgcc tcccagctga caccctgcaa ggccaccggg accgcttcat    840

ggagcagttt acaaagttga aagatctgtt ctaccgctcc agcaacctgc agtacttcaa    900

gcggctcatt cagatccccc agctgcctga gaacccaccc aacttcctgc gagcctcagc    960

cctgtcagaa catatcagcc ctgtggtggt gatccctgca gaggcctcat cccccgacag   1020

cgagccagtc ctagagaagg atgacctcat ggacatggat gcctctcagc agaatttatt   1080

tgacaacaag tttgatgaca tctttggcag ttcattcagc agtgatccct tcaatttcaa   1140

cagtcaaaat ggtgtgaaca aggatgagaa ggaccactta attgagcgac tatacagaga   1200

gatcagtgga ttgaaggcac agctagaaaa catgaagact gagagccagc gggttgtgct   1260

gcagctgaag ggccacgtca gcgagctgga agcagatctg gccgagcagc agcacctgcg   1320

gcagcaggcg gccgacgact gtgaattcct gcgggcagaa ctggacgagc tcaggaggca   1380

gcgggaggac accgagaagg ctcagcggag cctgtctgag atagaaagga aagctcaagc   1440

caatgaacag cgatatagca agctaaagga gaagtacagc gagctggttc agaaccacgc   1500

tgacctgctg cggaagaatg cagaggtgac caaacaggtg tccatggcca gacaagccca   1560

ggtagatttg gaacgagaga aaaaagagct ggaggattcg ttggagcgca tcagtgacca   1620

gggccagcgg aagactcaag aacagctgga agttctagag agcttgaagc aggaacttgc   1680

cacaagccaa cgggagcttc aggttctgca aggcagcctg gaaacttctg cccagtcaga   1740

agcaaactgg gcagccgagt tcgccgagct agagaaggag cgggacagcc tggtgagtgg   1800

cgcagctcat agggaggagg aattatctgc tcttcggaaa gaactgcagg acactcagct   1860

caaactggcc agcacagagg aatctatgtg ccagcttgcc aaagaccaac gaaaaatgct   1920

tctggtgggg tccaggaagg ctgcggagca ggtgatacaa gacgccctga accagcttga   1980

agaacctcct ctcatcagct gcgctgggtc tgcagatcac ctcctctcca cggtcacatc   2040

catttccagc tgcatcgagc aactggagaa aagctggagc cagtatctgg cctgcccaga   2100

agacatcagt ggacttctcc attccataac cctgctggcc cacttgacca gcgacgccat   2160

tgctcatggt gccaccacct gcctcagagc cccacctgag cctgccgact cactgaccga   2220

ggcctgtaag cagtatggca gggaaaccct cgcctacctg gcctccctgg aggaagaggg   2280

aagccttgag aatgccgaca gcacagccat gaggaactgc ctgagcaaga tcaaggccat   2340

cggcgaggag ctcctgccca ggggactgga catcaagcag gaggagctgg gggacctggt   2400

ggacaaggag atggcggcca cttcagctgc tattgaaact gccacggcca gaatagagga   2460

gatgctcagc aaatcccgag caggagacac aggagtcaaa ttggaggtga atgaaaggat   2520

ccttggttgc tgtaccagcc tcatgcaagc tattcaggtg ctcatcgtgg cctctaagga   2580

cctccagaga gagattgtgg agagcggcag gggtacagca tcccctaaag agttttatgc   2640

caagaactct cgatggacag aaggacttat ctcagcctcc aaggctgtgg gctggggagc   2700

cactgtcatg gtggatgcag ctgatctggt ggtacaaggc agagggaaat ttgaggagct   2760

aatggtgtgt tctcatgaaa ttgctgctag cacagcccag cttgtggctg catccaaggt   2820

gaaagctgat aaggacagcc ccaacctagc ccagctgcag caggcctctc ggggagtgaa   2880

ccaggccact gccggcgttg tggcctcaac catttccggc aaatcacaga tcgaagagac   2940

agacaacatg gacttctcaa gcatgacgct gacacagatc aaacgccaag agatggattc   3000

tcaggttagg gtgctagagc tagaaaatga attgcagaag gagcgtcaaa aactgggaga   3060

gcttcggaaa aagcactacg agcttgctgg tgttgctgag ggctgggaag aaggaacaga   3120

ggcatctcca cctacactgc aagaagtggt aaccgaaaaa gaatagagcc aaaccaacac   3180

cccatatgtc agtgtaaatc cttgttacct atctcgtgtg tgttatttcc ccagccacag   3240

gccaaatcct tggagtccca ggggcagcca caccactgcc attacccagt gccgaggaca   3300

tgcatgacac ttccaaagac tccctccata gcgacaccct ttctgtttgg acccatggtc   3360

atctctgttc ttttcccgcc tccctagtta gcatccaggc tggccagtgc tgcccatgag   3420

caagcctagg tacgaagagg ggtggtgggg ggcagggcca ctcaacagag aggaccaaca   3480

tccagtcctg ctgactattt gacccccaca acaatgggta tccttaatag aggagctgct   3540

tgttgtttgt tgacagcttg gaaagggaag atcttatgcc ttttcttttc tgttttcttc   3600

tcagtctttt cagtttcatc atttgcacaa acttgtgagc atcagagggc tgatggattc   3660

caaaccagga cactaccctg agatctgcac agtcagaagg acggcaggag tgtcctggct   3720

gtgaatgcca aagccattct ccccctcttt gggcagtgcc atggatttcc actgcttctt   3780

atggtggttg gttgggtttt ttggttttgt tttttttttt aagtttcact cacatagcca   3840

actctcccaa agggcacacc cctggggctg agtctccagg gccccccaac tgtggtagct   3900

ccagcgatgg tgctgcccag gcctctcggt gctccatctc cgcctccaca ctgaccaagt   3960

gctggcccac ccagtccatg ctccagggtc aggcggagct gctgagtgac agctttcctc   4020

aaaaagcaga aggagagtga gtgcctttcc ctcctaaagc tgaatcccgg cggaaagcct   4080

ctgtccgcct ttacaaggga gaagacaaca gaaagaggga caagagggtt cacacagccc   4140

agttcccgtg acgaggctca aaaacttgat cacatgcttg aatggagctg gtgagatcaa   4200

caacactact tccctgccgg aatgaactgt ccgtgaatgg tctctgtcaa gcgggccgtc   4260

tcccttggcc cagagacgga gtgtgggagt gattcccaac tcctttctgc agacgtctgc   4320

cttggcatcc tcttgaatag gaagatcgtt ccaccttcta cgcaattgac aaacccggaa   4380

gatcagatgc aattgctccc atcagggaag aaccctatac ttggtttgct acccttagta   4440

tttattacta acctccctta agcagcaaca gcctacaaag agatgcttgg agcaatcaga   4500

acttcaggtg tgactctagc aaggctcatc tttctgcccg gctacatcag ccttcaagaa   4560

tcagaagaaa ggccaaggtg ctggactgtt actgacttgg atcccaaagc aaggagatca   4620

tttggagctc ttgggtcaga gaaaatgaga aaggacagag ccagcggctc caactccttt   4680

cagccacatg ccccaggctc tcgctgccct gtggacagga tgaggacaga gggcacatga   4740

acagcttgcc agggatgggc agcccaacag cacttttcct cttctagatg gaccccagca   4800

tttaagtgac cttctgatct tggaaaaaca gcgtcttcct tctttatcta tagcaactca   4860

ttggtggtag ccatcaagca cttcccagga tctgctccaa cagaatattg ctaggttttg   4920

ctacatgacg ggttgtgaga cttctgtttg atcactgtga accaaccccc atctccctag   4980

cccacccccc tccccaactc cctctctgtg cattttctaa gtgggacatt caaaaaactc   5040

tctcccagga cctcggatga ccatactcag acgtgtgacc tccatactgg gctaaggaag   5100

tatcagcact agaaattggg cagtcttaat gttgaatgct gctttctgct tagtattttt   5160

ttgattcaag gctcagaagg aatggtgcgt ggcttccctg tcccagttgt ggcaactaaa   5220

ccaatcggtg tgttcttgat gcgggtcaac atttccaaaa gtggctagtc ctcacttcta   5280

gatctcagcc attctaactc atatgttccc aattaccaag gggtggccgg gcacagtggc   5340

tcacgcctgt aatcccagca ctttgagagg ctgaggtggt aggatcacct gaggtcagga   5400

gttcaagacc agcctgtcca acatggtgaa acccccatct ctactaaaaa taccaaaaat   5460

tagccgagcg tagtgacggg tgcccgtaat cccagctact caggaggctg agacaggaga   5520

atcacctgaa ccccagaggc agaggttgca gtgagctgag atcacgccat tgtactccag   5580

cctgggcaac aagagcaaaa ctccgtctca aaaaaaaaaa aaaattacaa atggggcaaa   5640

cagtctagtg taatggatca aattaagatt ctctgcccag ccgggcacag tggcgcatgc   5700

ctgtaatccc agaactttgg gaggccaaga cgggatgatt gcttgagctc aggagtttga   5760

gaccaggctg ggcatcatag caagacctca tctctactaa aattcaaaaa caaaattagc   5820

cgggcatgat ggtgcatgcc tgtagtctca gctagttggg gagctaaggt gggagaattg   5880

cttgagcttg ggaagtcgag gctgcagtca gccctgattg tgccagtgca ctccggcctg   5940

ggtgacagag tgagaccctg tctcaaaaaa aaaaagattc tgtgtcagag cccagcccag   6000

gagtttgagg ctgcaatgag ccatgatttc ccactgcact ccagcctgag tgacagagcg   6060

agactccatc tctttaaaaa caaacaaaaa attatctgaa tgatcctgtc tctaaaaaga   6120

agccacagaa atgtttaaaa acttcatcga cttagcctga gtcataacgg ttaagaaagc   6180

acttaaacag aagcagaggc taattcagtg tcacatgagg aagtagctgt cagatgtcac   6240

ataattactt tcgtaatagc tcagattaga atggctaccc cattctctag acaaaatcaa   6300

attgtcctat tgtgactctt ctaaaaatga agatgaagag ctatttaatg acacaccttg   6360

gattaaaacg ggaatcacat cttaaagcta aaaatgaacc tgcaagcctt ctaaatgagt   6420

cactgagcat cactagtgac aagtctcggg tgagcgtaaa tgggtcatga caagatggga   6480

cagcaacaaa atcatggctt aggatcgaca agaagttaaa aaacagctgc atctgttact   6540

taagtttgta agacagtgcc ctgagacctc tagagaaaag atgtttgttt acataagaga   6600

aagaggccag acatggtgtc tcacacgttt aatcccagca ctttgggagg caggggcggg   6660

tggatcacct gaggtcagga gttcaagact agcctggcca acatggtgaa accccgtctc   6720

tactaaaaat acaaaaatta gccgggcatg gtggcaggcg cctataatcc cagctactgg   6780

ggaggctgag gcaggagaat cacttgaacc cgggggacag aggttgtagt gagccaagat   6840

cgcaccactg cactccagcc tgggtcacag agtgagactc catctcaaaa aaaaaaaaga   6900

gagagagaga gaaagaaata gaagagaaga gccatcttgg cagggttatt ttatatctga   6960

gcaaggagtt taaatgagac tagtttagat tgtctgctga tgcagccgtc catagcagta   7020

cccctaaaat cccaccagaa tacgggtccc tctaacccag tggctggaag aaccactgtc   7080

tagagcaact tttcttggaa ctgtcccagc taccaagtca gacaccaagg tttatgccac   7140

caggtaacac gggaatcaca ggtacatgtc gctccggtca gattagttgg ctttggcccc   7200

tcgaccctgt gcaggagcta gttctcagct tgcagctgga agttccctct tagctcctta   7260

gtctagaggg gtctcctggc tccatttgac cctggtcttt aataaccggt cagcatcttg   7320

ctaccttcta ccacctttcc aaatctctgg aaatcctgcc agggaaagcc tccagttcca   7380

acattggctt tccaagcaaa ctggctttgc cctctctctg ccatccttgt cctccagaga   7440

ctgcaccacc tgtagcatag aaaaccacca ccacggacct gccagccatc ggcgcagcaa   7500

accagccagc tgtttgctgc caaattcctt cctctcccag gtccagacca aatacaagat   7560

cagcaccaca ccgtggtgtt gtcaggagcc aaagcaacag gaaacaattc aatgctgttg   7620

ggttcgattc tgagagtaga tttttccaga catgtctttc aggtgaccct caactacctc   7680

aggtttgaag gccctaaatg aaactgatta ccactcatag ggacaaaccg agggggttcg   7740

gttacatctt ggtgataatg cagttgtctc aaacttataa cagactcttt cacatttcag   7800

tttgcaggga tagggttggg tttgtttttc ttctgttttt aacctttccc ctgggtttcc   7860

attagggtag ttccttgaaa tgaatttcat ttttcactga gtgcctacct tcccagggca   7920

ggtggccact ggcttctgtt tccctccaac aatactttta ttatggtatt aagacctttc   7980

tttgtataat acattgcatc tgtgttttca atttttcaaa taaatatttc cgcctggcaa   8040

aaaaaaaaaa aaaaaa                                                   8056


<210>  905
<211>  965
<212>  DNA
<213>  Homo sapiens

<400>  905
acccgcgcag ggtgtgctag cgcgctcagc cctctccggc cggcttagtc tagttcccgg     60

gcctcgctcg gttccagaac tttccagaaa atgccgcgct ccctacggct caagggtcaa    120

atcgcgtcat ttccgggagg ggacgaaggg gtagttcttt cacctcggct gggcgcctag    180

aaaagcctag aaacagctcc ttttttcttc cgcctccgag tcttcgcgtc agcgtcctgc    240

gcagggccct tggggcgaat cgcggtgcgc gtcggggcga ccgccctccc tccctgggag    300

gggcgagggg gctagcggcg accgctgggg cgagcgcgcc tgcgcgctgg gtgatttttt    360

cacgtgtcgc cagggccgga ctgcgagtct ctttgcggcg ctacactaga gcagagtacg    420

agtctgaggc ggagggagta atggcaggac aagcgtttag aaagtttctt ccactctttg    480

accgagtatt ggttgaaagg agtgctgctg aaactgtaac caaaggaggc attatgcttc    540

cagaaaaatc tcaaggaaaa gtattgcaag caacagtagt cgctgttgga tcgggttcta    600

aaggaaaggg tggagagatt caaccagtta gcgtgaaagt tggagataaa gttcttctcc    660

cagaatatgg aggcaccaaa gtagttctag atgacaagga ttatttccta tttagagatg    720

gtgacattct tggaaagtac gtagactgaa ataagtcact attgaaatgg catcaacatg    780

atgctgccca ttccactgaa gttctgaaat ctttcgtcat gtaaataatt tccatatttc    840

tcttttataa taaactaatg ataactaatg acatccagtg tctccaaaat tgtttccttg    900

tactgatata aacacttcca aataaaaata tgtaaatgag tggttaatct ttaaaaaaaa    960

aaaaa                                                                965


<210>  906
<211>  1503
<212>  DNA
<213>  Homo sapiens

<400>  906
atggccacgg cggcttctaa cccctacctg ccggggaaca gcctgctcgc ggccggctct     60

attgtgcact cggacgcggc aggggctggc ggcggcgggg gtggcggcgg cggcggcggc    120

gggggcggcg cagggggcgg gggcggcggc atgcagccgg gcagcgccgc cgtgacctcg    180

ggcgcctacc ggggggaccc gtcctctgtc aagatggtcc agagcgactt catgcagggg    240

gccatggccg ccagcaacgg cggccatatg ctgagccacg cgcaccagtg ggtcacagcc    300

ctgccccacg ccgccgccgc cgccgccgct gccgccgccg ccgccgtgga ggcgagctcg    360

ccgtggtcgg gcagcgccgt gggcatggct ggcagccccc agcagccacc gcagccgccg    420

ccgccaccgc cgcagggccc cgacgtgaag ggcggcgccg ggcgcgacga cctgcacgcg    480

ggcacagcgc tgcaccaccg cgggccgccg cacctcggac ccccgccgcc gcccccacac    540

cagggccacc ctgggggctg gggggcggcc gccgctgccg cagccgcagc cgccgccgcc    600

gccgccgccg cgcacctccc gtccatggcc gggggccagc agccgccgcc gcagagtctg    660

ctctactcgc agcccggagg cttcacggtg aacggcatgc tgagcgcgcc accggggccc    720

ggcggcggcg gcggcggcgc gggcggtgga gcccagagct tggtgcaccc ggggctggtg    780

cgcggggaca cgccagagct ggccgagcac caccaccacc accaccacca cgcgcatcct    840

cacccgccgc acccgcacca cgcgcaggga cccccgcacc acggcggcgg cggcggcggc    900

gcggggcctg gactcaacag ccacgacccg cactcggacg aggacacgcc gacgtcggac    960

gacctggagc agttcgccaa gcagttcaag cagcggcgca tcaagctggg cttcacgcag   1020

gccgacgtgg ggttggcgct gggcacactc tacggcaacg tgttctcgca gaccaccatc   1080

tgccgcttcg aggccctgca gctgagcttc aagaacatgt gcaagctcaa gccgctgctg   1140

aacaagtggc tggaggaggc ggactcaagc accggcagcc ccacaagcat cgacaagatc   1200

gcggcgcagg gccgcaagcg caagaagcgg acctctatcg aggtgagcgt caagggcgcg   1260

ctggagagcc acttcctcaa gtgccccaag ccctccgcgc aggagatcac caacctggcc   1320

gacagcctgc agctcgagaa ggaggtggtg cgggtctggt tctgcaatcg gcgccaaaag   1380

gagaagcgca tgacgccgcc cgggatccaa cagcagacgc ccgacgacgt ctactcgcag   1440

gtgggcaccg tgagcgccga cacgccgccg cctcaccacg ggctgcagac gagcgttcag   1500

tga                                                                 1503


<210>  907
<211>  1545
<212>  DNA
<213>  Homo sapiens

<400>  907
tttccgcgag cgccggcact gcccgctccg agcccgtgtc tgtcgggtgc cgagccaact     60

ttcctgcgtc catgcagccc cgccggcaac ggctgcctgc tccctggtcc gggcccaggg    120

gcccgcgccc caccgccccg ctgctcgcgc tgctgctgtt gctcgccccg gtggcggcgc    180

ccgcggggtc cggggacccc gacgaccctg ggcagcctca ggatgctggg gtcccgcgca    240

ggctcctgca gcaggcggcg cgcgcggcgc ttcacttctt caacttccgg tccggctcgc    300

ccagcgcgct acgagtgctg gccgaggtgc aggagggccg cgcgtggatt aatccaaaag    360

agggatgtaa agttcacgtg gtcttcagca cagagcgcta caacccagag tctttacttc    420

aggaaggtga gggacgtttg gggaaatgtt ctgctcgagt gtttttcaag aatcagaaac    480

ccagaccaac catcaatgta acttgtacac ggctcatcga gaaaaagaaa agacaacaag    540

aggattacct gctttacaag caaatgaagc aactgaaaaa ccccttggaa atagtcagca    600

tacctgataa tcatggacat attgatccct ctctgagact catctgggat ttggctttcc    660

ttggaagctc ttacgtgatg tgggaaatga caacacaggt gtcacactac tacttggcac    720

agctcactag tgtgaggcag tggaaaacta atgatgatac aattgatttt gattatactg    780

ttctacttca tgaattatca acacaggaaa taattccctg tcgcattcac ttggtctggt    840

accctggcaa acctcttaaa gtgaagtacc actgtcaaga gctacagaca ccagaagaag    900

cctccggaac tgaagaagga tcagctgtag taccaacaga gcttagtaat ttctaaaaag    960

aaaaaatgat ctttttccga cttctaaaca agtgactata ctagcataaa tcattcttct   1020

agtaaaacag ctaaggtata gacattctaa taatttggga aaacctatga ttacaagtaa   1080

aaactcagaa atgcaaagat gttggttttt tgtttctcag tctgctttag cttttaactc   1140

tggaagcgca tgcacactga actctgctca gtgctaaaca gtcaccagca ggttcctcag   1200

ggtttcagcc ctaaaatgta aaacctggat aatcagtgta tgttgcacca gaatcagcat   1260

ttttttttta actgcaaaaa atgatggtct catctctgaa tttatatttc tcattctttt   1320

gaacatacta tagctaatat attttatgtt gctaaattgc ttctatctag catgttaaac   1380

aaagataata tactttcgat gaaagtaaat tataggaaaa aaattaactg ttttaaaaag   1440

aacttgatta tgttttatga tttcaggcaa gtattcattt ttaacttgct acctactttt   1500

aaataaatgt ttacatttct aaataaaaaa aaaaaaaaaa aaaaa                   1545


<210>  908
<211>  674
<212>  DNA
<213>  Homo sapiens

<400>  908
atctggcttg tccgcgcgat ttccggcctc tcggctttcg gctcggagga ggccaaggtg     60

caacttcctt cggtcgtccc gaatccgggt tcatccgaca ccagccgcct ccaccatgcc    120

gccgaagttc gaccccaacg agatcaaagt cgtatacctg aggtgcaccg gaggtgaagt    180

cggtgccact tctgccctgg cccccaagat cggccccctg ggtctgtctc caaaaaaagt    240

tggtgatgac attgccaagg caacgggtga ctggaagggc ctgaggatta cagtgaaact    300

gaccattcag aacagacagg cccagattga ggtggtgcct tctgcctctg ccctgatcat    360

caaagccctc aaggaaccac caagagacag aaagaaacag aaaaacatta aacacagtgg    420

gaatatcact tttgatgaga ttgtcaacat tgctcgacag atgcggcacc gatccttagc    480

cagagaactc tctggaacca ttaaagagat cctggggact gcccagtcag tgggctgtaa    540

tgttgatggc cgccatcctc atgacatcat cgatgacatc aacagtggtg ctgtggaatg    600

cccagccagt taagcacaaa ggaaaacatt tcaataaagg atcatttgac aactggtgga    660

aaaaaaaaaa aaaa                                                      674


<210>  909
<211>  1646
<212>  DNA
<213>  Homo sapiens

<400>  909
ggcggggcca ggagagaaag ctttgtggtt tggtctcagg gaagtagcag gcgccggttg     60

agagaactac ggccctgtcg gaaggtaacc tccggtgcaa acgaccatcg gcggcaggcg    120

agcggtacgc ttggcgtccg ggccttcctg ggcccgtctg aggaaacttg ctgctcgagg    180

ccaggctgcc taggacctgt cccttttttc tatactggct cccacatccg ggttttttct    240

ccgggacggc ccttcggatg cttgggccaa tgggaatcgc catttagggt gctccgccca    300

ccgggtcgcg tagagcatcc tggaagtcgt agtaaatctc tcgagagttc tctccgcacg    360

cgggctggag aagcgggtcc tacgcacgct ttgttgtcgc gctttgcctc cgtccttgcc    420

cctactcccg ccttacctga cttccttttc ggaggaagat ccttgagcag ccgacgttgg    480

gacaaaggat ttggagaaac ccagggctaa agtcacgttt ttcctccttt aagacttacc    540

tcaacacttc actccatggc agttcccgag acccgcccta accacactat ttatatcaac    600

aacctcaatg agaagatcaa gaaggatgag ctaaaaaagt ccctgtacgc catcttctcc    660

cagtttggcc agatcctgga tatcctggta tcacggagcc tgaagatgag gggccaggcc    720

tttgtcatct tcaaggaggt cagcagcgcc accaacgccc tgcgctccat gcagggtttc    780

cctttctatg acaaacctat gcgtatccag tatgccaaga ccgactcaga tatcattgcc    840

aagatgaaag gcaccttcgt ggagcgggac cgcaagcggg agaagaggaa gcccaagagc    900

caggagaccc cggccaccaa gaaggctgtg caaggcgggg gagccacccc cgtggtgggg    960

gctgtccagg ggcctgtccc gggcatgccg ccgatgactc aggcgccccg cattatgcac   1020

cacatgccgg gccagccgcc ctacatgccg ccccctggta tgatcccccc gccaggcctt   1080

gcacctggcc agatcccacc aggggccatg cccccgcagc agcttatgcc aggacagatg   1140

ccccctgccc agcctctttc tgagaatcca ccgaatcaca tcttgttcct caccaacctg   1200

ccagaggaga ccaacgagct catgctgtcc atgcttttca atcagttccc tggcttcaag   1260

gaggtccgtc tggtacccgg gcggcatgac atcgccttcg tggagtttga caatgaggta   1320

caggcagggg cagctcgcga tgccctgcag ggctttaaga tcacgcagaa caacgccatg   1380

aagatctcct ttgccaagaa gtagcacctt ttccccccat gcctgcccct tcccctgttc   1440

tggggccacc cctttccccc ttggctcagc cccctgaagg taagtccccc cttgggggcc   1500

ttcttggagc cgtgtgtgag tgagtggtcg ccacacagca ttgtacccag agtctgtccc   1560

cagacattgc acctggcgct gttaggccgg aattaaagtg gctttttgag gtttggtttt   1620

tcacaatcaa aaaaaaaaaa aaaaaa                                        1646


<210>  910
<211>  1231
<212>  DNA
<213>  Homo sapiens

<400>  910
agtacctgac attccaggcg cgagccacgg cgccggctcc tgttggtttt agtatctgtc     60

ttgttccact agaatctcaa ccccacaagg acaagaattt ttatctgttt tgttcactgc    120

tgttttttca gcatttatag cagctccagg cgcgtagcag agaatcatta aatatttata    180

gaaagattaa atacgctctt ccggaagcac cgacaaacaa gattaaatga gcttggattg    240

aacctcgtag cggcccgtag tactcctcct tcccgccatc ctatagatga aaggaagaaa    300

aggaaaagcc ccgcccctcg ctcggctgct ggaggcgagg gcttcggaag tcttcatgct    360

agtctcgtgg ggttccgcgg tgtcgtcgct ggctgtgcgc gtcatttccg ggcgtcacgt    420

aacggagtgg ccaacggcct gcagagcaac atgcccaagt tttattgtga ctactgcgat    480

acatacctca cccatgactc tccatctgtg agaaagacac actgcagtgg aaggaaacac    540

aaagagaatg tgaaagacta ttatcagaaa tggatggaag agcaggctca gagcctgatt    600

gacaaaacaa cggctgcatt tcaacaagga aagatacctc ctactccatt ctctgctcct    660

cctcctgcag gggcgatgat accacctccc cccagccttc cgggtcctcc tcgccctggt    720

atgatgccag caccccatat ggggggccct cccatgatgc caatgatggg ccctcctcct    780

cctgggatga tgccagtggg acctgctcct ggaatgaggc cgcccatggg aggccatatg    840

ccaatgatgc ctgggccccc aatgatgaga cctcctgccc gtcccatgat ggtgcccact    900

cggcccggaa tgactcgacc agacagataa ggatagaggg gaggccttat tgtatcggtt    960

ttatattacc tgttctgctt caccaggaga tcatgctgct gtgatactga gttttctaaa   1020

cagcataagg aagacttgct cccctgtcct atgaaagaga atagttttgg aggggagaag   1080

tgggacaaaa aagatgcagt tttcctttgt attgggaaat gtgaaaataa aattgtcaac   1140

tctttcagtt aaaagtgtgt tccctttttc ctcctctctg tgttctctgt gtattataaa   1200

agaaatgaaa cattccaaaa aaaaaaaaaa a                                  1231


<210>  911
<211>  1426
<212>  DNA
<213>  Homo sapiens

<400>  911
gggattggct actttaagtt cagagtacgc atgctctgac tttctctctc tttcgattct     60

tccatactca gagtacgcac ggtctgattt tctctttgga ttcttccaaa atcagagtca    120

gactgctccc ggtgccatga acggagacga cgcctttgca aggagaccca cggttggtgc    180

tcaaatacca gagaagatcc aaaaggcctt cgatgatatt gccaaatact tctctaagga    240

agagtgggaa aagatgaaag cctcggagaa aatcttctat gtgtatatga agagaaagta    300

tgaggctatg actaaactag gtttcaaggc caccctccca cctttcatgt gtaataaacg    360

ggccgaagac ttccagggga atgatttgga taatgaccct aaccgtggga atcaggttga    420

acgtcctcag atgactttcg gcaggctcca gggaatctcc ccgaagatca tgcccaagaa    480

gccagcagag gaaggaaatg attcggagga agtgccagaa gcatctggcc cacaaaatga    540

tgggaaagag ctgtgccccc cgggaaaacc aactacctct gagaagattc acgagagatc    600

tggaaatagg gaggcccaag aaaaggaaga gagacgcgga acagctcatc ggtggagcag    660

tcagaacaca cacaacattg gacccaaaag gggggaacat gcctggaccc acagactgcg    720

tgagagaaaa cagctggtga tttatgaaga gatcagcgac cctgaggaag atgacgagta    780

actcccctca gggatacgac acatgcccat gatgagaagc agaacgtggt gacctttcac    840

gaacatgggc atggctgcgg acccctcgtc atcaggtgca tagcaagtga aagcaagtgt    900

tcacaacagt gaaaagttga gcgtcatttt tcttagtgtg ccaagagttc gatgttagcg    960

tttacgttgt attttcttac actgtgtcat tctgttagat actaacattt tcattgatga   1020

gcaagacata cttaatgcat attttggttt gtgtatccat gcacctacct tagaaaacaa   1080

gtattgtcgg ttacctctgc atggaacagc attaccctcc tctctcccca gatgtgacta   1140

ctgagggcag ttctgagtgt ttaatttcag attttttcct ctgcatttac acacacacgc   1200

acacaaacca caccacacac acacacacac acacacacac acacacacac acacaccaag   1260

taccagtata agcatctgcc atctgctttt cccattgcca tgcgtcctgg tcaagctccc   1320

ctcactctgt ttcctggtca gcatgtactc ccctcatccg attcccctgt agcagtcact   1380

gacagttaat aaacctttgc aaacgttcaa aaaaaaaaaa aaaaaa                  1426


<210>  912
<211>  5066
<212>  DNA
<213>  Homo sapiens

<400>  912
gtgcgcccct ccgaacgtcc ccgggagccc agccagagcg agcgccgggg ccgggcgcgc     60

aggagtgaaa aggaggcggc ggccgcagct gcgagcaaca gatccggacg ccgcgagctg    120

acccgctctg ctgttgggcg attttttttt aattgcagaa aaatttatta aattggaaaa    180

tcttgcgttt ttcaatggcg ctggccccgg gtcagcgggc gattttctct gcatcaagat    240

gggctttgcc gtttccgtag tgggcaccag tggtggcctg attgtcagtc ttctcccggc    300

atttttaagg ccaggagccg agcgctgctt gtaggcgaat accctacaga gcggtttggc    360

tttttaaatt actgttatta ttttgggcag agaacagtcg gtctggtgca ccccgtcctc    420

gctgcagaag aggctgcgag tccgaggtgg gtctctcgga aggtgaaatt ccttctgggg    480

tgagcgagcc ccggccccgc gcgcagtcca gcggccccgc gtgtgtgccc tcgccctgcc    540

ggagccggga aaatggaggc tgtgattgag aaggaatgca gcgcgctcgg aggcctcttc    600

cagaccatca tcagcgacat gaaggggagc tatccagttt gggaagattt cataaacaaa    660

gcaggaaagc tgcagtccca gcttcggaca acagtagtag cagcagctgc cttcttggac    720

gcctttcaga aagtggctga catggccacc aacacacgtg gtgggaccag ggagattgga    780

tctgctctca ccaggatgtg catgaggcac agaagcattg aagccaagct gaggcagttt    840

tcgagcgctt taattgattg tctgataaac ccacttcaag aacagatgga agaatggaag    900

aaagtggcca accagctgga taaagaccac gcaaaagaat ataagaaagc ccgccaagag    960

ataaaaaaga agtcctcgga tacgctgaaa ctgcagaaga aagcaaaaaa agtggacact   1020

cttgggagag gtgatatcca gcctcagttg gacagtgctc tccaagatgt caatgataag   1080

tatctcttat tggaagaaac agaaaagcag gctgtccgga aggctttgat tgaagaacgt   1140

ggccgattct gtaccttcat ctctatgctg cggccagtga ttgaagaaga aatctcaatg   1200

ctaggggaaa taacccacct tcagaccatc tcggaagatc taaaaagcct gaccatggac   1260

cctcacaaac tgccctcctc aagtgaacag gtgattctgg acttgaaagg ttctgattac   1320

agctggtcgt atcagacgcc accctcttcc cccagcacca ccatgtccag aaagtccagt   1380

gtctgcagca gcctgaacag tgtcaacagc agtgactccc ggtccagcgg ctcccactcg   1440

cattccccca gctcacatta ccgctaccgc agctccaacc tggcccagca ggctcctgtg   1500

aggctgtcca gcgtgtcctc ccatgactca ggattcatat cccaggatgc cttccagtcc   1560

aagtcaccat cccccatgcc gccagaggcc cccaaccagt tgtctaacgg gttttctcac   1620

tatagtttat caagtgagtc ccacgtgggg cccacgggtg caggcctttt ccctcattgc   1680

ctgcctgcct cccgcctgct ccctcgggtc acctctgtcc accttccaga ctacgctcat   1740

tattacacca ttgggcccgg catgttcccg tcatctcaga tccctagctg gaaggactgg   1800

gctaagcctg ggccctatga ccagcctctg gtgaacaccc tgcagcgccg caaagagaag   1860

cgagaaccgg accccaacgg gggaggaccc actaccgcca gcggcccacc tgcagcagct   1920

gaggaggctc agagaccacg gagcatgact gtatcggctg ccaccaggcc tggtgaggag   1980

atggaggctt gtgaggagct ggccctggcc ctgtctcggg gcctgcagct ggacacccag   2040

aggagcagcc gggactcgct tcagtgctcc agcggctaca gcacccagac aaccaccccc   2100

tgctgctctg aggacaccat cccttcccaa gtttcagatt atgattattt ctctgtaagt   2160

ggtgaccagg aggcagatca gcaggagttc gacaagtcct ccaccattcc aagaaacagc   2220

gacatcagcc agtcctaccg acggatgttc caagccaagc gtccagcctc aactgctggc   2280

ctccccacca ccctgggacc tgctatggtc actccagggg ttgcaactat ccgacggacc   2340

ccttccacca agccttctgt ccgccgggga accattggag ctggtcccat ccccatcaag   2400

acacccgtga tccctgtcaa gaccccaacc gtcccagacc tcccaggggt gttgccagcc   2460

cctccagatg ggccagaaga gcggggggag cacagccctg agtcgccatc tgtgggtgag   2520

ggcccccaag gtgtcaccag catgccctcc tcaatgtgga gcggccaagc ttccgttaac   2580

cctccacttc caggcccgaa gcccagtatc cctgaggagc acagacaggc aattccagaa   2640

agtgaagctg aagaccagga acgggaaccc ccaagtgcca ctgtctcccc aggccagatt   2700

ccagagagtg accctgcaga cctgagccca agggatactc cacaaggaga agacatgctg   2760

aacgccatcc gaaggggcgt gaaactgaag aagaccacga caaacgatcg ctcagcccct   2820

cgcttttctt aggttcacaa gaaatgcgcc ggtggggaat gaactgtttc attaataaaa   2880

cctaatttgt cttgatccat tccactctat aataaaacaa aagattttgt aggcaactcg   2940

gaatatagct cttttgaaag tactcgacac ctttagataa gaattaaaac caacctatgt   3000

aactgacata atcttgatct tttaatttgt aaatattgac aattttcttt ctgcacattt   3060

taatcttagt ttcccttttg atttttctga aggtgccaaa ttccatttaa cttttttaca   3120

agtctttgta aaattttaaa tgcataaagg gggttggggc aggggaacca cgaagtagtt   3180

aattttagaa aaggatttac tatacttcac tcttcttttt ttttccccac aagcttttgt   3240

agatgcattg tagtagtcta gcttagaagc aaatgcaagt tattttaatg tacaaactaa   3300

atgggtaaga ggtaaaatct tcatttaaat atactatgtt ctggatgaaa agagcaggag   3360

taacaattga tgagcaatat tcagagtgaa gtaaatctgg aaatggtaga ctgtgttggg   3420

attgggggga gggccatggg aggggtacat cgtcaacata gccgatcctg ttacatttaa   3480

gagtagcctc gtaggttgaa tttcttctgg tagcttcatg gtaaatgcat ccgaataagc   3540

catactggat tgcagtgttt gtttctgtag ggtgtttaag gacttgactt cctttctccc   3600

atgattcctc tggactgcac acagcaccca caaccagccc catgcatgct gctgcctctg   3660

ggcagtcgta gaatctccca cttcagtttc tcgttgattg tactcacctt tatggaatcc   3720

aaatacatcc aaaagggtaa ggcagtttta aaaatgtgaa aacatttaaa aatgataata   3780

gcagggaatt cttagattat agtaaatgcc ttttacttaa ctgtgcccag caggctgggt   3840

gcgttaaaaa gcccaagtat tttgaaaaaa ctcgaacaga tttgacaagg gtagccagct   3900

tggagtctag caacttgcca atgtgtttac caatctgggg gcttgttttt cttttcttct   3960

ttcaaataaa tggcagttaa ctggctttac agtaaacatt gaagagagga ggatttgttt   4020

attgtcactg ggaatctgac cactatactg tccttttttt gtattctggg taaatgtttt   4080

ttggaaaaga tttgtctttt ctaagtggaa gttaaatttg ttatactgcc catcccctaa   4140

agccaacaga gatttgtaga tttaaaggga tcacatttga agacaatagt gtttaagaaa   4200

gcaagcaagt cccttagcag tcaggtcata acagggcaca tttctgaccg aaccctctca   4260

aggcagagga ggagtttggt gggtttcata caccctgcag attcctgttg gctctaaccc   4320

tcaattacct aatcttatgc tttaacacat aactgcattg gatgtgagag taacgtaccg   4380

tatggtcatt gttctatata ttaacattga acactgctgc gattgctcaa ggacatttta   4440

tgttacggct ttaaagcaaa ggcatgatta ttagaaacta tttaagcttt tttctttgaa   4500

aaacaagctc cttttacaga atataaacaa cagtagtgcc tgtggtttag cccaccaatc   4560

ttgatgacta aaagtagctg atgcattgtg catatgatgc ttgagatggt ttttgcaaaa   4620

gcagaaatcg ctgcaaggta atcacaatag ataaaagtgg tattttaaac ctttgaaata   4680

aatggatgta actgtacctt ggtacagctt ttcacttgtt tagtttttaa acgttagtat   4740

aatctgaata aataaaatgt tgccaaattc aatgtagaaa gaatgtgaca acacaccttg   4800

ggtagttctg cttgtgtttt tgcatattgt aaaagcagtg tcacagctaa aaagaaagaa   4860

atcgtttcta acagtaaatt attgtgcttt agttgctagt ttgtactgag agttgacctc   4920

tccctgtgca gttttttgtt ctaaacttgt ataaataaca attgtgtaat gtgtctccct   4980

cctacattgt aacaattgct tcagcctacg ttataaataa agaaccacta gattaaaaaa   5040

gtcctgtatt tcaaaaaaaa aaaaaa                                        5066


<210>  913
<211>  1828
<212>  DNA
<213>  Homo sapiens

<400>  913
gatgggcctc cgggacggtg tgccaggccg gggccaagtc ggaggcccct cgctctgggt     60

gggcgctggg gcccgcgagg gctactgtaa ggacccctgg cttctgagga tactgcgtct    120

agaactttct ccgtatgggg ccttgaggtg cttggtcgag acctgccttt gcgcttggtc    180

ccgaatcctg ccctctagga gtcgctcttg cgggcctcca gcccaccgga ggcgaagcgg    240

ccccgggcgg aaggccgctg gatcctcgag ggaggtgccg gtttctctcc gcgggcgccg    300

tggggacggt gggaggcggg ggcgtcggca gcgcttggac taggtgcggc cttgggcctg    360

cctggtagcg gggatttggg cccgcagagc gcccgcctct gcggctgagt tctgcctggc    420

ggggaaggga gcgcccgatg ggtgccgagg cgtcctcctc ttggtgccct ggcactgctc    480

ttcccgaaga acgcctttca gttaaacggg cgtcggaaat ctcgggcttc ctggggcagg    540

gatcgtcggg agaggccgct ctggacgtgt tgacacacgt gctggagggg gcaggaaaca    600

agctcacatc ttcctgtggg aaaccttcta gcaacaggat gagtctgcag tggactgcag    660

ttgccacctt cctctatgcg gaggtctttg ttgtgttgct tctctgcatt cccttcattt    720

ctcctaaaag atggcagaag attttcaagt cccggctggt ggagttgtta gtgtcctatg    780

gcaacacctt ctttgtggtt ctcattgtca tccttgtgct gttggtcatc gatgccgtgc    840

gcgaaattcg gaagtatgat gatgtgacgg aaaaggtgaa cctccagaac aatcccgggg    900

ccatggagca cttccacatg aagcttttcc gtgcccagag gaatctctac attgctggct    960

tttccttgct gctgtccttc ctgcttagac gcctggtgac tctcatttcg cagcaggcca   1020

cgctgctggc ctccaatgaa gcctttaaaa agcaggcgga gagtgctagt gaggcggcca   1080

agaagtacat ggaggagaat gaccagctca agaagggagc tgctgttgac ggaggcaagt   1140

tggatgtcgg gaatgctgag gtgaagttgg aggaagagaa caggagcctg aaggctgacc   1200

tgcagaagct aaaggacgag ctggccagca ctaagcaaaa actagagaaa gctgaaaacc   1260

aggttctggc catgcggaag cagtctgagg gcctcaccaa ggagtacgac cgcttgctgg   1320

aggagcacgc aaagctgcag gctgcagtag atggtcccat ggacaagaag gaagagtaag   1380

ggcctccttc ctcccctgcc tgcagctggc ttccacctgg cacgtgcctg ctgcttcctg   1440

agagcccggc ctctccctcc agtacttctg tttgtgccct tctgcttccc ccattccctt   1500

ccacagctca tagctcgtca tctcggccct tgtccacact ctccaagcac attacagggg   1560

acctgattgc tacacgttca gaatgcgttt gctgtcatcc tgcttggcct ggccaggcct   1620

ggcacagcct tggcttccac gcctgagcgt ggagagcacg agttagttgt agtccggctt   1680

gcggtggggc tgacttcctg ttggtttgag cccctttttg ttttgccctc tgggtgtttt   1740

ctttggtccc gcaggagggt gggtggagca ggtggactgg agtttctctt gagggcaata   1800

aaagttgtca tggtgtgtac gtggaaaa                                      1828


<210>  914
<211>  2737
<212>  DNA
<213>  Homo sapiens

<400>  914
tgacgaaggg gcccgaccgc gccgcgtttc gggagcggac gtccgagcca cggccgaggc     60

ccgattagtc cgtccggcac cgctcgggca ctttcggaag ggaagaggtg gagaaccgac    120

gttcgggagc attcggcctc ggggacattc ggctcgtctc ggctcggcct cgggctgact    180

cggcttccgc cggcggcggg aacgggcgaa acccgcggca ctaagctctc tctgagaggc    240

agaattgcgc cggccgccgg cgagaatctg cctagagccg tccagccctg tcggccgggg    300

acgacagccg cctcagcctg tcaggacagt gaggagagca ggggccgagt ctctcggaag    360

ccctcgtgag gactcggacc tattcggact gattcggctt cccacttcgg ggaacttcga    420

ccctcctcgg ttcaggactc ggtctcggct cggcggcttc gtgcaggttc ggctcctact    480

cgggcagcct ctgttcgcct cggctccgct ccgcgggcgg actcggctcg gctctgctcg    540

gcggctggct gccttttcgg tccctattcg ggcggcggct tcgggcggcc tcggcccagc    600

tcgggcgtcc tcttcgggcc ccgcttcggg ctccgcgacc ggcgcttcgg gcggtcccgg    660

acggcgcctt cgggaaggct cggcggagtc cggatggagg actcggactc ggcggcaaag    720

cagctgggcc tggctgaggc ggcggcggtg gcggccgcgg ccgctgtggc ggcggcggcc    780

gcggccgcgg caggaggcga ggcggaggag ccggtgctga gcagggacga ggactcggag    840

gaggacgcag actcggaggc ggagcgggag acgccgcggg tcacggcagt ggcggtgatg    900

gcggcggagc ccgggcacat ggacatgggc gccgaggccc tgcccggccc cgacgaggcc    960

gccgctgccg cagccttcgc agaggtgacc acagtgacag tggccaacgt gggggctgct   1020

gcagacaatg tcttcaccac gtctgtggcg aacgcggcat ccatctcagg acatgttctg   1080

tctggtagga cggcccttca gatcggggac agcctgaaca ccgaaaaagc gacactgatt   1140

gtcgtccaca cagatgggag catcgtggag accaccgggc tgaaaggccc ggcagctccc   1200

ctcaccccag gtcctcagtc tcctccaacc cctctggctc ccggccaaga aaaaggtgga   1260

actaaataca actgggaccc ttctgtgtac gacagtgagc tgcccgtacg gtgccggaac   1320

atcagcggca ctctgtacaa gaacaggctc ggctcaggcg gccggggacg gtgcatcaag   1380

cagggggaga actggtacag tcccaccgag tttgaggcca tggcaggaag agccagcagt   1440

aaggactgga aaagaagcat tcgctacgcg ggccgaccct tgcagtgcct catccaggat   1500

gggatcttaa accctcacgc tgcctcttgc acctgtgctg cctgctgcga cgacatgacc   1560

ttaagtggcc cagtcaggct ttttgtgcct tacaaaaggc gcaagaagga gaatgaactg   1620

cccacaactc ccgtgaagaa ggactccccc aagaacatca cattgcttcc agccaccgcg   1680

gctaccacct tcaccgtgac cccctcggga cagatcacga cctcgggggc actgaccttt   1740

gaccgagcgt ccacggtaga ggccactgct gtcatatcag agagtccggc ccagggcgac   1800

gtcttcgcag gggccacagt ccaagaggcc agcgtgcagc ccccatgcag ggccagccac   1860

cctgagcctc actaccccgg ctatcaggac agctgccaga tcgcaccgtt tccagaagct   1920

gcgttgccaa cgtcacatcc caaaatagtg ttgacatccc tgcctgcgct ggcggtccca   1980

cccccgactc ccaccaaagc ggcacctccc gcgttggtca atgggctgga gctgtcagag   2040

ccgcggagct ggctgtacct agaagagatg gtcaactcct tgctcaacac agcgcagcag   2100

ctgaagacgc tgtttgagca agccaagcat gccagcacct accgagaagc tgccacaaac   2160

caggccaaga tccacgctga cgcagagcgg aaggagcagt cctgcgttaa ctgcggccgg   2220

gaggctatga gcgagtgcac cggctgccac aaggtcaact actgctccac cttctgccaa   2280

cgcaaggact ggaaggatca ccagcacata tgcggccagt cagcagctgt caccgtccag   2340

gcagacgaag tccacgtggc tgaaagcgtg atggagaagg tgaccgtgtg aggctccatc   2400

ggccgccctg ggagctgggg cccctcgcac tcctgtgagg cttttgcagg tcgaaggccc   2460

ccctgaggac tctgggggga cgttgagaag aggggtgtgg gaaggtaaag aaacttgctg   2520

gacaagtcat taacacactt taagcgaatg gtgccctggg aagcgcactc cccctgcccg   2580

ggccccctgc ccgctcgcgg acagattttt tatccctggg atcatgagcg tccggtcttg   2640

cccacagggc ctgtgctgcg acgcacatac atacgtgttg tgtctgtcaa taaagtgtaa   2700

ataaggtctc cctgccaaaa aaaaaaaaaa aaaaaaa                            2737


<210>  915
<211>  1504
<212>  DNA
<213>  Homo sapiens

<400>  915
ggttacctca tcgccgcctc cgggaggccc cgctcgctcg cgccggcggc tggggcggcg     60

actccaggcg cggaagcgag agaaggatag aggcacagag gctccgggag gcagcgctgc    120

cccccgcgcc ccgcaccgct gcgggacccg cgccgcgaga ggggcggact tcggcgcctc    180

gcgcgtccgc cggcgcctgg gttggcgctg cggggcggag gcggtgtctg agcgccgctc    240

cggctctgct ctctctcgag cttcggcacc cgcccgagcc gctcgcgcgc ccgccacctg    300

tctgcccact cggctgtctg tctgccctcc cgccgccagc tcctgcctcg ggcctgccct    360

ctccggtctc ggtgctccga ggggcgacga gaagcgcgac ggggccgtgg cgcaccgggc    420

agggcgcgcg gggcgcacgg cctgggggcg cacggtgcgg cgccggccca tgaggctttc    480

cagcgcgggg agcgacagcg ccggccggcc atggggggta gcctgcgggt ggccgttcta    540

ggcgccccgg gcgtgggcaa gacggccatc atccgccagt tcctgttcgg tgactacccc    600

gagcgccacc ggcccacgga cgggccgcgc ctctaccgac ccgcggtgct gctcgacggc    660

gccgtctacg acttgagcat ccgcgacggc gacgtcgctg gccccggctc gagccccggg    720

ggtccggagg agtggccaga cgctaaggac tggagcttgc aggacacgga cgccttcgtg    780

ctcgtctacg acatctgcag cccggacagt ttcgactacg tgaaggccct gcggcagcgc    840

atcgcggaga ccaggccggc gggcgcgccc gaagcgccca tcctcgtggt aggcaacaag    900

cgggacaggc agcggctgcg cttcggaccg cggcgcgcgc tggccgccct agtgcgcagg    960

ggctggcgct gcggctacct cgagtgctcc gccaagtaca actggcacgt gctgcgtctc   1020

ttccgcgagc tgctgcgctg cgctctggtg cgcgcgcgcc ctgcacaccc ggccctgcgc   1080

ctgcaggggg cgctgcatcc cgcgcgctgc agcctcatgt gacccgatcg gacagtgcca   1140

tccatgggcc ccaccttgtg actgggacaa tcagggacct ggattggacg ggatcgccca   1200

acttcactgg gactggacag ggaagtctcc gccctgattg gatgaggaaa gctccaaccc   1260

agtctcctaa gcgactggcc cccttttgaa cctcattgga cccaaccagg tcccaagctc   1320

cattggagat gaccagtcct ttctgggacc tcaatgggtc acaatcccat tggatggaaa   1380

ggacttggct atgaacttga ctggaaacac gcagcctgct cctggagctt cactggacat   1440

attctttatg ccacacctac cacgggataa taaaagggaa aataatttga aaaaaaaaaa   1500

aaaa                                                                1504


<210>  916
<211>  3668
<212>  DNA
<213>  Homo sapiens

<400>  916
aggctggaaa gtggaggatc cggtttgctc tgggcgggtc tggaagcaga gccggcggag     60

ggagcgccgg ggccctgggc tgcaggaggt tgcggcggcc gcggcagcat ggtggtgccg    120

gagaaggagc agagctggat ccccaagatc ttcaagaaga agacctgcac gacgttcata    180

gttgactcca cagatccggg agggaccttg tgccagtgtg ggcgcccccg gaccgcccac    240

cccgcagtgg ccatggagga tgccttcggg gcagccgtgg tgaccgtgtg ggacagcgat    300

gcacacacca cggagaagcc caccgatgcc tacggagagc tggacttcac gggggccggc    360

cgcaagcaca gcaatttcct ccggctctct gaccgaacgg atccagctgc agtttatagt    420

ctggtcacac gcacatgggg cttccgtgcc ccgaacctgg tggtgtcagt gctgggggga    480

tcggggggcc ccgtcctcca gacctggctg caggacctgc tgcgtcgtgg gctggtgcgg    540

gctgcccaga gcacaggagc ctggattgtc actgggggtc tgcacacggg catcggccgg    600

catgttggtg tggctgtacg ggaccatcag atggccagca ctgggggcac caaggtggtg    660

gccatgggtg tggccccctg gggtgtggtc cggaatagag acaccctcat caaccccaag    720

ggctcgttcc ctgcgaggta ccggtggcgc ggtgacccgg aggacggggt ccagtttccc    780

ctggactaca actactcggc cttcttcctg gtggacgacg gcacacacgg ctgcctgggg    840

ggcgagaacc gcttccgctt gcgcctggag tcctacatct cacagcagaa gacgggcgtg    900

ggagggactg gaattgacat ccctgtcctg ctcctcctga ttgatggtga tgagaagatg    960

ttgacgcgaa tagagaacgc cacccaggct cagctcccat gtctcctcgt ggctggctca   1020

gggggagctg cggactgcct ggcggagacc ctggaagaca ctctggcccc agggagtggg   1080

ggagccaggc aaggcgaagc ccgagatcga atcaggcgtt tctttcccaa aggggacctt   1140

gaggtcctgc aggcccaggt ggagaggatt atgacccgga aggagctcct gacagtctat   1200

tcttctgagg atgggtctga ggaattcgag accatagttt tgaaggccct tgtgaaggcc   1260

tgtgggagct cggaggcctc agcctacctg gatgagctgc gtttggctgt ggcttggaac   1320

cgcgtggaca ttgcccagag tgaactcttt cggggggaca tccaatggcg gtccttccat   1380

ctcgaagctt ccctcatgga cgccctgctg aatgaccggc ctgagttcgt gcgcttgctc   1440

atttcccacg gcctcagcct gggccacttc ctgaccccga tgcgcctggc ccaactctac   1500

agcgcggcgc cctccaactc gctcatccgc aaccttttgg accaggcgtc ccacagcgca   1560

ggcaccaaag ccccagccct aaaaggggga gctgcggagc tccggccccc tgacgtgggg   1620

catgtgctga ggatgctgct ggggaagatg tgcgcgccga ggtacccctc cgggggcgcc   1680

tgggaccctc acccaggcca gggcttcggg gagagcatgt atctgctctc ggacaaggcc   1740

acctcgccgc tctcgctgga tgctggcctc gggcaggccc cctggagcga cctgcttctt   1800

tgggcactgt tgctgaacag ggcacagatg gccatgtact tctgggagat gggttccaat   1860

gcagtttcct cagctcttgg ggcctgtttg ctgctccggg tgatggcacg cctggagcct   1920

gacgctgagg aggcagcacg gaggaaagac ctggcgttca agtttgaggg gatgggcgtt   1980

gacctctttg gcgagtgcta tcgcagcagt gaggtgaggg ctgcccgcct cctcctccgt   2040

cgctgcccgc tctgggggga tgccacttgc ctccagctgg ccatgcaagc tgacgcccgt   2100

gccttctttg cccaggatgg ggtacagtct ctgctgacac agaagtggtg gggagatatg   2160

gccagcacta cacccatctg ggccctggtt ctcgccttct tttgccctcc actcatctac   2220

acccgcctca tcaccttcag gaaatcagaa gaggagccca cacgggagga gctagagttt   2280

gacatggata gtgtcattaa tggggaaggg cctgtcgggc tgaccccggg tttgtaccac   2340

ctgggccgca ctgtcctctg catcgacttc atggttttca cggtgcggct gcttcacatc   2400

ttcacggtca acaaacagct ggggcccaag atcgtcatcg tgagcaagat gatgaaggac   2460

gtgttcttct tcctcttctt cctcggcgtg tggctggtag cctatggcgt ggccacggag   2520

gggctcctga ggccacggga cagtgacttc ccaagtatcc tgcgccgcgt cttctaccgt   2580

ccctacctgc agatcttcgg gcagattccc caggaggaca tggacgtggc cctcatggag   2640

cacagcaact gctcgtcgga gcccggcttc tgggcacacc ctcctggggc ccaggcgggc   2700

acctgcgtct cccagtatgc caactggctg gtggtgctgc tcctcgtcat cttcctgctc   2760

gtggccaaca tcctgctggt caacttgctc attgccatgt tcagttacac attcggcaaa   2820

gtacagggca acagcgatct ctactggaag gcgcagcgtt accgcctcat ccgggaattc   2880

cactctcggc ccgcgctggc cccgcccttt atcgtcatct cccacttgcg cctcctgctc   2940

aggcaattgt gcaggcgacc ccggagcccc cagccgtcct ccccggccct cgagcatttc   3000

cgggtttacc tttctaagga agccgagcgg aagctgctaa cgtgggaatc ggtgcataag   3060

gagaactttc tgctggcacg cgctagggac aagcgggaga gcgactccga gcgtctgaag   3120

cgcacgtccc agaaggtgga cttggcactg aaacagctgg gacacatccg cgagtacgaa   3180

cagcgcctga aagtgctgga gcgggaggtc cagcagtgta gccgcgtcct ggggtgggtg   3240

gccgaggccc tgagccgctc tgccttgctg cccccaggtg ggccgccacc ccctgacctg   3300

cctgggtcca aagactgagc cctgctggcg gacttcaagg agaagccccc acaggggatt   3360

ttgctcctag agtaaggctc atctgggcct cggcccccgc acctggtggc cttgtccttg   3420

aggtgagccc catgtccatc tgggccactg tcaggaccac ctttgggagt gtcatcctta   3480

caaaccacag catgcccggc tcctcccaga accagtccca gcctgggagg atcaaggcct   3540

ggatcccggg ccgttatcca tctggaggct gcagggtcct tggggtaaca gggaccacag   3600

acccctcacc actcacagat tcctcacact ggggaaataa agccatttca gaggaatcgt   3660

gaaaaaaa                                                            3668


<210>  917
<211>  2333
<212>  DNA
<213>  Homo sapiens

<400>  917
acgcgcctcg gggaacagcc tggcccaaag cctcactcct cacgtcccag gggtggacgg     60

gggtccggga gcctcgagct ccgggcaggc gtggcgaggc tgaagtctgg gtcttccgcg    120

ccccgcgagg accacgccgc gacgtaatcg cccgcgggga ggcgcggagt ggagccgcag    180

ccagctcctc ccgcactctg ctgaccgcgc actagctgtc cttgaggcaa gaatacttgg    240

gagcggaaaa aaggtggggg tgttccccgg ggcgggggag gaggggcaag gccccagcaa    300

gcctcttgga aatctctccc tgggagggga cgaggggcgg ccttcagttg caaatgggaa    360

gggctcggat accggatttg aagcagtgtt tgcacggcaa gcgcagcttt tatttagact    420

gccggtttgt gagggttggc tctcagagcg ctgatggcga ttatagtgga acttcacctt    480

cacctgctca tgcgccccgc agcgcgcccg ctcccacgcc cgcgtagctg aggacccaga    540

ctcgccagga aaggctagtg aggctggggc ccgggcgggc ccggccgggc cgggtcaggg    600

gaggggcctg gcggcagggg cggggcctca gctaaaggcg cggagcaccc ggcgccgaga    660

gcgctgagta gagcggcgcc cgctcgagag aagtggggcc gagatcgcgc cgtcccagcc    720

cgcccgccgg cgtctgcgct gctccggcgc ccttacccct gctggccctt gcaaggcgcg    780

accggcggcc atgcagcccc ggggctgagg ccgccccatg gcaaagccgg cggtcccggc    840

gacgacggcg catggagaac ttccgtaagg tgcgctccga agaggcgcca gcggggtgcg    900

gggccgaggg aggcggcccg ggctccggcc ccttcgcaga cctggcgccg ggcgcggtgc    960

acatgcgggt caaggaaggc agcaagatcc ggaacctgat ggccttcgcc accgccagca   1020

tggcgcagcc agccacgcgc gccatcgtct tcagcggctg cggccgggcc accaccaaaa   1080

ccgtcacgtg cgccgagatc ctcaagcgcc gcctggcggg cctgcaccag gtcacgcggc   1140

tgcgctaccg gagcgtacgc gaggtgtggc agagcctccc gcctgggccc acgcagggtc   1200

agacgcctgg cgagccggcc gctagtctca gcgtacttaa gaacgtgccc ggcctcgcca   1260

tcctactttc caaggacgcg ctggatccgc gacagcccgg ctaccagccc ccgaatcccc   1320

atcctggtcc ctcgtccccg ccagccgcgc cagcgtccaa gaggagccta ggggaacccg   1380

cagctggaga aggctccgcg aagcgatcgc aacccgagcc aggggttgcg gacgaggatc   1440

agacggcctg aaactccgga ctgtgggcca cctagtccgg caggatcttc cgccagcgcc   1500

tccaccttca gatgtacctc cagcctttca ctcctcggtc ctccggagcc cacaacctgg   1560

acacagctcc tcaagacagg tagcatggac cttaaggcga caagagaggg gccccaggag   1620

tggcaggaga ggatccccga ccaccctagg gaaacttcgt gcgataattg ctgcttatgc   1680

ccgtgttgcg tgaagacacg gaacttcacc ttttctggga ccttctttgg gggagaatgg   1740

tggacagtgg gattctggaa acttgtttgg gacccccaag ggttaaagcc acccagcatt   1800

cacgaagagc acctgaagta tggaagctga gaagagttat tggaatcacc cccaccgttg   1860

acagaggaag gcagggggtg agaattaact gcttgagggt aggagagtct gagatgtggg   1920

ggccctattc cgctccccgc cctgggacag ttttcctttc tagttttctt tcccctgctt   1980

cagaggagca tctctgaggg ttctagctct tttaacaccc cttttccccc tgctggccca   2040

gagggagacc caggactgaa ctctccaggc ctcctcccct gagccctgca gctggctgga   2100

gtcttgcttc caataaaaca agcacaaaaa tggctgtgtc ccccattttt tttctaacca   2160

cccgcctgtg cagagacagc tctcgcctgg ccccttgtgt ctcccctccc ctccagcctt   2220

gcgtcctgag tctttggagt cttcagggtc aggcacagag actgaacagc ttcaaaatgg   2280

tgcaaggcac tgcccagtcc ctggcttctt cctctctcct cccccactcc gcc          2333


<210>  918
<211>  4440
<212>  DNA
<213>  Homo sapiens

<400>  918
ccctcccgct ccccgccccc gcccccgccc ccgcctccgc cgcggccccc acctctgcct     60

ccttctactc gggcgccccg gcggccgcca cctctcccca gcccaggaga ggctgcggag    120

ccgcagccgc ccagaccgcg cagcgcggga ggcaggttcc gcacgaaata aatcagaatg    180

agttatgcag aaaaacccga tgaaatcacg aaagatgagt ggatggaaaa gctcaataac    240

ttgcatgtcc agagagcaga catgaaccgc ctcatcatga actacctggt cacagagggc    300

tttaaggaag cagcggagaa gtttcgaatg gaatctggaa tcgaacctag tgtggatctg    360

gaaacacttg atgaacgaat caagatccgg gagatgatac tgaaaggtca gattcaggag    420

gccatcgcct tgatcaacag cctccaccca gagctcttgg acacaaaccg gtatctttac    480

ttccatttgc agcaacagca tttgatcgag ctgatccgcc agcgggagac agaggcggcg    540

ctggagtttg cacagactca gctggcggag cagggcgagg agagccgaga gtgcctcaca    600

gagatggagc gtaccctggc actgctggcc tttgacagtc ccgaggagtc gcccttcgga    660

gacctcctcc acaccatgca gaggcagaag gtgtggagtg aagttaacca agctgtgcta    720

gattatgaaa atcgcgagtc aacacccaaa ctggcaaaat tactgaaact actactttgg    780

gctcagaacg agctggacca gaagaaagta aaatatccca aaatgacaga cctcagcaag    840

ggtgtgattg aggagcccaa gtagcgcctg cgcttgcgtg gtggatccaa caccagccct    900

gcgtcgtggg acttgcctca gatcagcctg cgactgcaag attcttactg cagtagagaa    960

ctctttttct cccttgtact tttttttgac ctggcatctt tttataggga aaaatggcct   1020

ttgtaggcag tggaaaactt gcaaggaaag ctgccgtctc tttggcagtc tgatgcagag   1080

cctgcactct ggcactcgct gaagaatctg gaaggttgcg gtttgctctt ccagtgttcg   1140

ggggcctctg gctgctgaag gattcggtct accacggagg gctgtgctgt taggctgcat   1200

cccactcaaa atacaggaaa agcacgaatc atgattctgc tttctgttag cttaggcaga   1260

cattgggcct tcacctacaa gtttttcctt acccctgtgg tttttgtgtt tttttttttt   1320

tctttttcca taggaaagaa tatataaatt tgtaaatcct aattcaaaga tggctcatgt   1380

gtgagggcat tgagtttgat ttgttttccc tttggtctgg gttgtgtggc ttttggggga   1440

tgcgtgtgag ggggctatgt gttttttaat tttttaaata tatattttgg tgctgtgtgt   1500

ggtaagagac ttgttcctag tggatcaatg aaccatctct tctgggcagt tttgttgaaa   1560

ataaaggttt ctctttgatt tcaagaatga ccaaaatggc ctctaaaaga tgttaatcat   1620

ctcaaatgac cttttgtctt tggggcgttc ttccccctgt gatagcggca gtggcttttt   1680

ctggtacctg cagctggaaa ggccacttgg ccctgtgctg agtgagcggc cttcattaga   1740

gcgaggcagc ccttggccgg tggggacgca gagccccagc aggtggtgca cgactgttgg   1800

cggaaggaac gcgtgttcat cctcagtgat ctgccctcca gcatctcggc agcatctcat   1860

cctccatcgt cagctggctc tgccgatgtc ctgcttctgt tcactcacag aactgtcccc   1920

tgctccgtgg tgggcaggag ggaagtggtg cagggctgcg tgcattgcct gcgagtcggg   1980

acagttgatg ggcacatggc cttgtagctc tgggcacaga tgtgtttgga ttcattgcag   2040

cggaccaccg ggcactgttg accccactga gcagtgctaa gtgttggttt agtggatgtt   2100

cgtggaattg ctgacccatc caagggcgtc ctttggagcc agtggagcct gccggcgcat   2160

ctgaggggca gaatgctgct agcacttgaa tctgggatct cgccttattc tcaagtagca   2220

aggcatctcg acaagcatgg tctaggtctg gtggccagct tgccagtacc tgagccggtc   2280

gggtcatctg cctctgaggg accgtcctca ccgagctcct gcatcccttg agtgttgatc   2340

aggaggcgtc cacagcattg ttctcgcctc tgaatgatgc ttctttctgt gttggagcct   2400

ggcgaagttg tgttttcaag ccctctactt ctctttccag tgggtaggag cttttggcag   2460

tgtttacttt acctagatgg cttatataat ccagtaagag atgcaaagat aaaattgctg   2520

cggttgttac agaagcatgg cggcctccag actgacccat tggttgccct ttagattttg   2580

taaggatgcg gtgctgggga ggtggtgctt ccctaccccc tagaaatgct gccttccaac   2640

taccactctc ccagatgtga cccttgcgat tatttcctct gaggtttgag gatgaagata   2700

agttggaggg aaagagagta actaataggg gatgaaatat agcagaagct agaagaaagc   2760

ggtgaggtga gagagatgca tctgcacgtt ttcttcaaca gcaccaggtg attcagcata   2820

ttcctaatta cctttcacta ttcgtgtata taagatcgtt tacttgcata atatatcatc   2880

aatttgacat attcttaaaa ctagagggtg tgagaagcac agcaatagga agtctctcca   2940

caaactaggg gaacacaaat ggggtcattc acgtgcctgg actgtcacta tgtggctgtc   3000

acgtgaagtg ctggtgttga tttccatttc agccagtggg tagctgataa gccagtgcca   3060

gcatccagca tgagcagatg tcggggagac tgggaagtct ccagcgttac tgctctcctt   3120

cccttcatga taagccagtg ccagcatcca gcgtgagcag acgtcgggga gactgggaag   3180

tctccgatgt tactgcctgc cttcctttcg tgtgaggggc tgcacttgct tttcttgtga   3240

tctgttagtg gacgaggtct tccaaggaag tgctttgcac actttctttg ctccttttta   3300

cagtctttgt ctttgcagca agcaaatgaa attaagccac tttgggataa tgaacattca   3360

gtataattct actttgtctc attttggatc tcactgttgt ctttataaaa atggcacatt   3420

ttacaaagta gtttattctt attatacttt ctgctggaga gtgccttgaa ataaaatgtg   3480

agagtattct ggtactctgt gttccagatg catgaaattg ggtgaggaat aacccctagt   3540

ctggaatctt tgtgaagcat agggttattg caaggcaaat gggaactaac acatcttgcc   3600

atttgaatca gggtctccag tttctagaaa aggcagacac tggttgggac caaagtctcc   3660

atggcacatg actgaagact ggtggtcgtg tgtgtgcgga gtccacggaa gcctcgggga   3720

ggtggagctg ctccttccat tccgtcagga cgtgatctga aaacatgtag agaagatgag   3780

ttgaggacag cttttctaag gcaatgtgat gtctttgctt tcttatttct ctttctctgc   3840

gttgttagtt ttgaagagtg gaggagctag gggctccaga aagaatctta cacatgtgtt   3900

gaagacattg atgtcatagg gagcggggag ctgcattccc ttctgggctg ttactgctaa   3960

atctcagtat gaacagacca ggcggaaagc ttggtggcca agcagtctgt gtgcttcccc   4020

gctgatggag aacgttgcgt tgttcacaat agggcctcat gggtgtagcc gcatggcaga   4080

cccatggctg gcgcagctgc ctgttgccgt ctgtcttcag taactgctgc tctgttaact   4140

gttctattct gatactacgc gtgttgtttt ttacaacagg tatgtttttg tttcagaaat   4200

atgtattgct tttctcatat tttttgcaaa ttgtattgtc aacatgggtc atttaaagtc   4260

ctgtatgaac cataacctgc tgtggtacct ttgtacatgt ttgattctgt attctttatt   4320

ccagtgtggc atatgtgccc ctctgtatct tttgagaagt gcggaatagg ttgcttctac   4380

cacctgttct taatgtaaca gtaaaagttt tcacattttt ctcagaaaaa aaaaaaaaaa   4440


<210>  919
<211>  8501
<212>  DNA
<213>  Homo sapiens

<400>  919
ggccggctcc gcagcgccgc gcaggcgccc cagggccacg ccgaaccgag cccctcctgc     60

tccgtctagg agtcaaaatg gcggcgaggg gaacctggag cagtcccgga gcctgagcca    120

ctgacaggag aggagagggc ggcggcggcg gcggtgggag gaggatggcc gggggtgctg    180

gcgccggtgc ggacggcggt gctggtggcg gcggcggcgg aggcgacggc agcggtccca    240

gcggcagcag cagcggcggg aggagcctcc gggaaatgga tgaaaagagg ctgctggatc    300

cagggttgaa ggttcataaa ggcctctggg attatactct gaagaacccg cagacggaat    360

gcctgagtga ctgaagaaaa tgggtgctaa tgcatctaat tatcctcatt catgttcccc    420

gagggtaggg ggaaattcac aggcccaaca gacttttata gggacctcat cctattctca    480

gcaaggctat ggttgcgaat caaagttgta tagccttgac catggccatg agaaaccaca    540

agacaaaaaa aagagaacct ctggtcttgc caccctcaaa aagaagttta ttaagcgtcg    600

gaaatctaat aggtctgccg atcatgccaa gcagatgcga gaactcctct ctgggtggga    660

tgttagagat gtcaatgcat tagtggagga atatgaggga acatcagcat taaaggagct    720

ttctctacaa gccagtttgg ctagaccaga agcccggaca ttgcagaaag atatggctga    780

tctttatgag tacaagtatt gtactgatgt agacttaata tttcaagaaa cttgttttcc    840

tgttcatcgt gccattttgg cagcaaggtg tccatttttt aaaacactgc tttcttcctc    900

accagagtat ggggcagaga taataatgga catcaataca gctggtattg atatgcccat    960

gttttctgct ttgttacact acctttatac aggagagttt ggaatggagg actcaaggtt   1020

tcaaaatgtc gatatccttg ttcagcttag tgaagaattt ggaacaccaa attcccttga   1080

tgtagatatg cgtggactct ttgattacat gtgttattat gatgtcgtcc ttagtttttc   1140

ttcagactct gaactggttg aagcttttgg tggaaatcag aactgtttag atgaagagct   1200

caaagcccac aaggctgtta tttctgcacg gtccccattt tttcgaaatt tattacaaag   1260

gaggatacga actggtgaag aaatcacaga ccgaactttg aggactccca caagaattat   1320

attagatgag tccattatac caaaaaaata tgcaacagtg atattacact gtatgtatac   1380

cgacgtggtg gacctctctg ttttgcactg tagcccctct gtggggagtc tcagtgaagt   1440

tcaggctctc gtcgcaggga agccaaacat gaccagggca gaagaagcca tggaacttta   1500

ccacatagca ctgttcttgg aatttaacat gcttgcacaa ggctgtgagg atatcattgc   1560

tgagagcatc tcattagata ccttaattgc catcctcaag tggagttctc atccatatgg   1620

ctctaaatgg gtgcaccgac aagctttaca tttcctctgt gaggaatttt cccaggtcat   1680

gacttcggat gttttttatg aactcagcaa agaccatctg cttactgcta tccagtctga   1740

ctacctacag gcaagtgaac aagatatcct taaatatctg attaaatggg gagagcatca   1800

gttgatgaaa agaatagcag atagagagcc aaacttactg agtggcactg cccatagtgt   1860

gaacaaaaga ggtgtaaaaa gacgggacct ggacatggaa gagctcagag agatcctttc   1920

ttctctctta ccttttgtgc gaattgaaca catcttacct ataaacagtg aagtcttaag   1980

tgatgcaatg aaaagaggct tgattagtac tcctccatca gatatgcttc ctacaacaga   2040

aggtgggaag tcaaatgcct ggttacggca aaaaaatgct ggcatctatg ttcgtcctcg   2100

actcttctct ccctatgtgg aagaagcaaa gtcagtgcta gatgagatga tggtggaaca   2160

aacggatctt gtgcgcttgc gaatggttag aatgtccaat gtgccagaca cgctctacat   2220

ggtcaataat gccgtgccac agtgttgtca catgatcagc caccagcaga tcagcagcaa   2280

ccagtcaagc cctccttcag ttgtagccaa cgaaattcca gttcctcgtc tcctcattat   2340

gaaagacatg gtcagacgac tgcaggaact gcggcacacg gagcaggtgc agagggccta   2400

tgccctgaac tgcggggaag gcgccactgt cagctatgaa attcagattc gagtgctaag   2460

agagtttggt cttgcagatg ctgctgcaga gctgttgcag aatcctcaca aattctttcc   2520

tgatgaacgt tttggggatg aaagtccact cttgacaatg agacagcctg ggagatgtcg   2580

cgtaaacagt acacctcctg cagaaaccat gtttacagat ctggactctt ttgtggcctt   2640

ccatccaccc ttgccccctc caccacctcc ctaccacccc ccagctaccc caatccataa   2700

ccaactcaaa gcaggctgga agcaaagacc tcccagtcag cacccttcac gttcattttc   2760

ttatccctgt aatcattcgc tgttccactc cagaacagct cctaaagctg gccctccccc   2820

agtctacttg ccgagtgtga aagctgcacc gcctgattgt accagcactg caggactggg   2880

cagacagacg gtggctgctg ctgccgccac caccacctca acagcaacag cagcagcagc   2940

agcagcatct gagaagcaag tgcgaacaca acctgtgctg aatgatctga tgccagacat   3000

cgcggtgggt gtgtccacac tgtcactcaa ggacaggagg cttccagagc ttgctgtaga   3060

cacagaatta agccagtcag tttctgaagc aggaccaggg cctccccagc atctgtcgtg   3120

tattccacag agacatacac acacttctcg gaaaaaacac acactagagc aaaaaacaga   3180

caccagagaa aatccacagg aatatccgga tttctatgac ttctcaaatg ctgcttgcag   3240

accttctact cctgctctca gcagacgcac cccttcccct tcgcaaggtg gatattttgg   3300

tcccgatctg tacagccaca ataaggcatc accaagtggc ttaaagtcag cctacctacc   3360

tggtcagacg tctcctaaaa aacaggaaga agctaggaga gaatatccac tttcccctga   3420

cgggcatcta cacagacaaa agaatgagcc gatacacctg gatgtcgttg agcaacctcc   3480

ccagcggtca gactttcctt tggcagcccc agaaaatgct agtaccggtc cagcccatgt   3540

caggggacga actgcagtag aaactgactt gacttttggg ctgactccta acagaccttc   3600

actttctgca tgtagctctg aagctcccga agagagatcc ggtagaagac tggcagacag   3660

tgagtccctg ggccatggag ctcagagaaa tacagatttg gaaagggaag attcaataag   3720

cagaggaagg aggtcaccaa gcaagccgga cttcctctac aaaaagtctg ccctctgaga   3780

gcaacctcca agtcgtctgt gcctgagatg tgaaacatcc cattttatga tgtaacccaa   3840

caacttacag accagttcat caatgccagc tgataactcg gtttcacatg attttgttct   3900

agtttttgtg tatatatgtg tttattagac atggcatgct aagaaggttt tgtttttttt   3960

ttttaatgtt gcatctgtct aatttgtctt tgaacaatta tgtcgggagg catttttaag   4020

aacaagcagg ctggcacttt ttatttctct ttacaaatga tggaattttt ttgcacttgt   4080

acatttattt tctctgtatt gattttatat cagtatgtta aactttattg ccacatttaa   4140

aggactgtat tttcatactt ttttgcattt tacctttcat ctaccaatcc atgtgcattg   4200

gattgcacac taagatgtat tttcttacga aatagttctg tgtttatttt ttaattatag   4260

aaattccaaa gaacagcaca tcagaatgct cctctctttt cagtaattgt tttagttcag   4320

agatcttccc gctcagcctc cataaatcta atgtcatttt ttttttaata agtcctagga   4380

gctgggcttc attcctccag cgggagtcca gtcagggtcc tgaagtttgc tggttcagga   4440

aagaacagga aagagaaaag ccttctgtgc ccaggctaaa gctgttacat ttccacagtg   4500

tggatgcagt cagaatccct gcacattctg gtcataagga ttagagtcac cagatgaggc   4560

tctaaacaga tcgcatccct tggaattaga aagcagtgga gaccgggcgc agtgactcac   4620

acctgtgatc ggcacttcgg aaggccgagg cgggcagatc actgaagctc aggagttcaa   4680

gaccagcctg ggcaacatgg cgaaactcca tttctataaa aaatacaaaa aaaaaaaaat   4740

ctagccaggc gtggtggtgc gtgcctgtag tcccagctac ttggggggct gaggtggcag   4800

gatcgcttga gcctgggagg ttgagactgc agtgagccaa gattgcacca ctgtgctccc   4860

acctgggcaa cagtgagacc ctgtctcaaa aaaaaaaaaa aaggcagtgg aaatagagaa   4920

gtaacttaaa ggtcacactg acagaatttc tggttctgag cgtcaactct ccagctgtga   4980

tggcggaact gactgcttgc tgcctttaat tgtcttgctc tctatgggaa aaaaacaaaa   5040

gggcttcagt ctcatggatg ttatttggtg tttgtaaaga tacgttttct tttaaacgat   5100

tttcaaaata tgtctaaatt ttggtgttgt gtaatgcata atgctttctc accaacagaa   5160

aaaaggaaaa aaattgtttt cagttaaaca ctacatgtcc tacttgaact ccactgggac   5220

gctggtttgg catttactaa accactgagc acatggggtc tttcaggatc ctctcccttg   5280

gaagggcaat gtgtgagcta aggactgttt tttttcttac tctccaatgt aaatatatga   5340

gtatttgagt ttttaaatca cttcaacatt atttgagcat ttactttgta tttttacaaa   5400

cacataaaca cacagccgta gcacttagaa gaaaagaggc tttctaagca ttccttcctc   5460

tgcaggatat ttgggatcct cttttctatg tatgtatata tataaaaaac tatgaatcac   5520

tcacactcac tcgaaaacta tgcagggcta gggagcgttt atgagctacc gggtaaatga   5580

attacatgca ctttgaagta aataggtttt ctattgggtg tcaacaacgc tgatttctcc   5640

caaaactata gtttctctta cggtcttttc ctcctttacc ctgtggatat acactcagga   5700

ataatctgac attttagaaa agccgaacag tagatagtct ccaagatggg aaacatgtcg   5760

tgtgtctgca cgccccggca aactgccgcc actcgttctg ctgcctgact ggttagctgc   5820

tgtgcgggtg cgctcggtga cactggtggt ggtgcacgct cccgagctcc cagagttaac   5880

actaatctgc aggtcggctg tgcatcgcat tcgaggctcc ttttttaaag agaaaagcat   5940

aggcctctgt tctcatttgt aagaagtttg actcataata gaagacggtg tcttttgaag   6000

cccagtctct gtctgtcttc agaaacaaaa gtgaatgccg tcatgttcct tgatgtgtgt   6060

ttctgccaca tatgtatgtt gacatgttca tgtactgcgc cggtactgca agtaagactc   6120

aacagaccta atttggatgg ggagaaaaac tctcatccct gacccttccc cccccgcaaa   6180

tgttagacca gagctgttga tcccacacat tcatttttct gaaaattcat gaactattct   6240

ctcatatccc tgaaatataa aagtaagtgg ccactattcc taagattatt tagtttataa   6300

agtttgcttt taatcataca atagcttacc tggctaaaac tttgcgtata aagggaaaac   6360

ttgctttaat ctgtgggatt gcggaccgat gcgacttgca gaaggtaaac aggcgtgggt   6420

tttgtgtgcg ttaggttagg tgttagtgga cttttaatgt atcttgtgaa gtatggttac   6480

tagggtaggt tcaagagcta catgcctctg gcttttgaac ccatctatta aatctttttt   6540

aatgctgtac taagataaat gtgaagtctg agtaaggttg ctctcagaaa aaaaaaaaaa   6600

gcatatatat atataaaata aaatttaggc catgggaact ggcattttac ttggtatagg   6660

aatttaatga gaaccaaatc acaaaaatac cagatctcct tttgagatcg tggacaatca   6720

ggcctttgga caatcaccgc ttccagtgcc cgctgtgcgt tgaggttaga gacctaccgt   6780

ttacacgcta gagccgagag gacgttcaag tttcttaaag atgctgttgg tcttttttct   6840

tatgttattg ttttagtttt gtgattttga tgaataattg aagttcagag tcacccgtgg   6900

ctcctaagga aaaaacagca tcatgaaagg caaaaagtat ttgaaacgta attgtttcaa   6960

ttttccacgc ccgttctcac atgccccctt tagctttatt tctgggaaca tgtcactaga   7020

cctcagctag cctgacaccg caataacccg ttaggctttg aggcttttca gtgaattctt   7080

gacatttaaa tcttcttata gaattcttta tgaagcctta actaattctt gtttttgctt   7140

cctcagaaac tttttattgc atctgccatc cttcattgga tttttgtttt ggtttgttgt   7200

tgccattcta gcaatgagct tagtccttgt acatctgcat taaggtgccg atgcagaagg   7260

caaattggaa acacgcgcca gcggcagtgg ggctcaaagc cgacctccat gcatcattct   7320

ctagagttga aaggattgac atttctcagt aactacccgg caaaatatat attttcataa   7380

tgttgaattt gccttttagg aaaacaatgt ttcatgaaac acttgtaaga tacttatttt   7440

gaaattaatt ataaggcatt catattttta ggactgaatt caaagggaaa tgcttctttg   7500

actttttttc attgttcggt tgactttcag ctttctggag tgacaaagca gcagtgatgg   7560

gtgctattcc tggttctgtg gtggtttact ttgtctacta agtgatttac tttcaaacct   7620

cattacagat aatcttacta aaagacttaa catgcacact gctaaaaggt gttttactgt   7680

tttccattaa cgctgttgta tgaacaatat ttggtgacat gttgtctttt tgtcctgtag   7740

attgtcatat ctgttatgta gttatccttt tggcaagtcc tttgattttt ttttcctcta   7800

gaaaatcctc agactgtcaa tcttccatat tttgaatatt ataatgctgt ggccatttct   7860

atagaaagat tacttgcaag tgtgtgtctt gaaaataacc tcttgtattt gtgtgtttat   7920

gtgagttctg tctaagagat cagataagct ctggaagctt catcatctgt acctacatgt   7980

aactgtatct gggttacatg ggcaggcggt accaagtcct gctcttcgat ggggtggctg   8040

agagataaag gttcctgaac tctccttgct gtgtatgcac cacatctgta cttcagagag   8100

gtggaaaatc atctacaaca ctgcgtttct tgtggttgtg ctgttactgg tataaagtca   8160

agtgccttca atgctaaagg ctcagaaatt tttcttaaac tgatttcatg tcctatgcaa   8220

gtgttttcta caacctgcat aaccagtact ttgtaaaact tgtttacgct tcaattgtac   8280

atagtgattt ttaaagaaat atatagtatt tttatttagg tacctccaaa cttgaattcg   8340

tctgtgtgaa gcattgtaaa acgatacatt tctcttttga gtaccattac agttgtacag   8400

aggttttcac tgcttctatt tttctactgt tactgataag catgtaacac tgactttatc   8460

ctacatatag ttggcatttc aaataaatgg cttgtataga a                       8501


<210>  920
<211>  895
<212>  DNA
<213>  Homo sapiens

<400>  920
aaatgaactc cctccagctt agctttcacc cggtggtgtt cccgggagga gagggcggag     60

ggcggaggga acttgcaccg aagcatcact cgagacccca aacctccagg cctgaggccc    120

agccagcgcc caatggatga caaaaagaag aaacggagtc ccaagccctg cctggcccag    180

ccagcccagg ccccaggcac actacggagg gtccctgtgc ctaccagcca cagcggctcc    240

ttggccctag gacttcctca tctgccatcc cccaagcagc gggccaagtt caagagagta    300

ggcaaagaga agtgccgccc agtcctggct ggaggtggaa gcggctctgc aggcacgccc    360

ctgcagcact ccttcctgac cgaggtgact gatgtctatg agatggaggg gggactcctg    420

aacctgctca atgatttcca ctctggccgg ctgcaggcct tcgggaagga atgctccttt    480

gagcagctgg agcacgttcg ggagatgcag gagaagctag cccggctgca cttcagcctg    540

gatgtgtgtg gggaggagga ggacgatgaa gaggaagagg atggggtcac tgaggggctg    600

ccagaggagc agaagaagac aatggctgac cgtaacctgg accagctgct tagcaatctg    660

gaagacctca gtaattctat ccagaagctg cacctggccg agaacgccga gcctgaggag    720

cagtccgctg cgtaggcgtc ccacgcaggc ccacactgcc cctctcattc tcttcaaact    780

gtgacttttt acagactcgg gcgggtgttc tgcggccccc caggtgctat gggggagggg    840

ggcgttgaat ggaattaaac cagaaagaaa gcaagcgaaa aaaaaaaaaa aaaaa         895


<210>  921
<211>  4834
<212>  DNA
<213>  Homo sapiens

<400>  921
tacactccag tcatggcggc ccgacaggcc gtgggcagcg gggctcagga gacatgcggt     60

ctggatcgga ttttggaggc attgaagctg ctgctgagcc cgggaggctc gggctcaagt    120

tcactacagg tcacaaaaca tgatgtcttg ttggctactt taaaatctaa cctgtctgct    180

ttggaggaca agtttctgaa ggatcctcag tggaagaatc tgaaactcct aagagatgaa    240

attgctgata aggcagaatg gccacaaaac tctgtggatg tcacttggag ttttacctct    300

caaaccttgt tgttgctttt gtgcttgaag gaaaccatga tccgccttgc agctaatttc    360

aatccaggta aacccaaccc taggactccg gaagttgctc ctgccctgag ccccgatgca    420

cttagtatct cacaacagaa gactgtccag ttcgttttgc agtttgtagt taccttgggt    480

atctgcccct atctcatgcc tggtgttgga gtccctttga gatatagaac tgaatttggt    540

gccgtcgttc aagacgtggt gtgttttgat gctgcccccg atgcaactcg aagactgtac    600

accagctgca aggcccttct gaatgttgct cagcacacat ctctggggag cttgatcttc    660

tgccaccact ttggggatat cgcagcaggt ctgtgccaac tgggattctg cccaaccaaa    720

agaaaactgc taacacctgc agaagaggtt ctaactgaag aggagagaac cctatccagg    780

ggggccttga gagacatgct ggatcaagtc tatcagccct tagcagtccg ggaactgctt    840

atcctccagg gaggaccacc ccagtcctgc acagatgtga agacacagat gaggtgtcgg    900

gccccagctt ggcttcggcg tctatgtgga cagctgctct ctgaaaggtt aatgagacct    960

aatggtgttc aggcagtagt ccggggcatt ttggaaggag caggtgcggg agcagctggt   1020

ggaagtgatg ctgaggtgac ggctgctgac tggaagaagt gtgacctgat cgcaaagatt   1080

ttggcctctt gtccccagca gtctctttca ccagagaatt actacaggga catctgcccc   1140

caggttctgg atttatttca ctttcaagat aaattgacag cacgacaatt tcagagagtt   1200

gccaccacta cctttataac tttgtcaaga gaacgcccac atttggcagc aaagtatttg   1260

ctccagccag tgttagctcc tcttcatcga tgtttgaata cagcagagct ttcagagagt   1320

gacatggtac caggaactat tttggtgaca gaagaagaac ttagtagatg cattgaggat   1380

gtgtttaagg tgtacgtggt tgggaatgaa cctttaacag ttttgatgga ttccctgctt   1440

ccagtcctgg gagtgctttt tcttctctac tgttttacta agcagagtgt gtctcacata   1500

aggtcacttt gccaagaaat cttattatgg attctgggga agctggaaag gaagaaggca   1560

attgccagcc tgaaaggatt tgcagggttg gacaaagctg tgccctctct ccattctctg   1620

tgtcagttta gagttgccac tcaaggtggc attatgatta ccatcaaaga ggccattagt   1680

gatgaagatg aagatgaagc cctgtaccag aaggtatcct ctgagcaggg ccgggtggag   1740

catctcgggg acttgctgtc ccactgccag gaatgcggtt tggcaggaga cttcttcatc   1800

ttctgtttga aagagttgac tcatgtggcc tcggaaaatg aaacagagtt aaaaactgag   1860

cccttctcca gcaagagcct cttggaatta gagcaacatc agactcttct tgtggaaggc   1920

caagagcgga agctgcttgt cctgcagctg atggctgttc tgtgcgagag aatgtctgag   1980

cagatattca caaacgtcac tcaggtggtg gactttgtag cagcaacatt gcagagagcc   2040

tgtgcaagcc tggcccatca ggcagagagc accgtggaat cacagacgct gagcatgtcc   2100

atggggctgg tggctgtcat gctaggagga gctgttcagt tgaagtcaag tgattttgct   2160

gttctgaagc agttgttgcc tctgttggag aaggtatcca acacataccc tgatccggtc   2220

atccaagaac tcgctgttga tctccgcatc accatctcta cccatggagc ctttgccact   2280

gaggccgtca gcatggctgc ccaaagtaca ctgaacagaa aagatctgga agggaaaata   2340

gaagagcagc aacaaaccag tcatgaaaga cccactgatg tagctcatag ccaccttgaa   2400

caacagcaga gccatgagac agccccccag acaggcctgc agtcaaatgc tccaatcatt   2460

cctcaaggag tcaatgagcc cagcactact acaagtcaga aatctggaag cgtaaccaca   2520

gaacagctcc aagaggttct tttgtcagct tatgaccctc aaattccaac acgggctgct   2580

gccctgcgta ctctttccca ctggatagag cagagagaag caaaagccct tgagatgcaa   2640

gagaagcttc tcaagatatt cttggaaaac ttggaacatg aagacacttt tgtatatcta   2700

tctgcaattc agggggttgc cctgctgtca gacgtctatc ctgagaaaat cttgccggac   2760

ttgttggctc aatatgacag cagcaaagac aagcacacac cagagaccag aatgaaagtc   2820

ggggaagtcc ttatgcgaat cgtcagggca ttaggagaca tggtctcaaa gtaccgagaa   2880

cctttgatcc ataccttcct gaggggagtg agagatcctg atggtgctca cagggccagc   2940

agcttggcca accttgggga gctgtgccag aggctggact ttctgctggg ctccgtggtc   3000

catgaggtaa cagcttgcct gattgctgtg gccaaaacag atggtgaagt tcaagtacgc   3060

agagctgcca tacatgtggt tgtgctgctg cttcggggac tcagccagaa agctactgag   3120

gtgctgagcg ccgtcctcaa ggatctctac cacctgctga agcacgtagt gtgtctggag   3180

cccgatgacg tggccaagct ccatgcccag ttggccctag aagagctgga tgacatcatg   3240

aaaaacttcc tgttccctcc acagaagctg gagaagaaga tcatggtcct gccgtagacc   3300

tggctccaag gacgtggagg aggcaggcag ggccaggcac ccagagccgt gcccaggtct   3360

tccagcaggt ggccctgctg cctcttgagt gctggcagca tggctgaccc tcggggtggt   3420

tttatggtgc aggtcacttg ggtcttcagg gtcccttccg agggcatgtg ttcagcactc   3480

ccgcgttcag cctgaggggt gtacagttaa gagaagacag ttacagatct cattaatcta   3540

catttttcac tgtcctctag cattgaaaga aggatgtcta cctggtgaaa gtatatttta   3600

acatgactga tggaatttca ctaattgccc actctcttgg aacttgagga gaagcggttg   3660

gccacccata tgtcacctag ctctatattc tttcaggctg agattcttct tcaggaaaat   3720

gaggagcaga actggccacc cttggctgct caagaggcat ttcagagtag gagatgcagt   3780

tggaggtggg gaggggaagg aaatagttat caaataatgc aaaatggaat aaagttatct   3840

tggatggaaa gaacagggct aaatctggtc ctctggtgtc gagatggaaa actgtggagt   3900

tgaagaggct ctgatgccca gaaaggacaa tcaagctggt tgactcttcc agagaagaag   3960

ggtaagccct gtatttatcc tcccaggcca ttcttcttca ctcctgctgc tgtttgcaga   4020

gagttgccct gattatcagg agaaaagaac cacgagcatc cagagagttt acatcctgcc   4080

ttctgtcctc tgctccttca gaaagatgaa tgcctagaca atgggttcac actgaatgca   4140

ggctggaaag aatgcatgct ggtggcctaa tgccagggct gttgaaacaa tttcagatat   4200

agcactgtgg tctccacttt atttctttat atgttttggc cgctgcattt tgattgcagc   4260

taaaagagat aacagaaagg agatactggc tggctgcttc atattagccc tctctgttgt   4320

caacaccttg atgaggccaa cccagagatg cttgatcagt cctcagcttt gcagggctag   4380

gtacagaatt ttatcacagg attttatcac gctctctggg gtgactagat ccacaggaac   4440

caaaacgcag tttccaaaag ctcgagtgac tgaaggatct atacacaaac atggctattt   4500

gctagttaac aacaggatat ttctctctgg ccagatcaca gacatggttc tgagtcagat   4560

cttccttggt ggcatccctt taaagaggcc atcttatgaa caggatcaca agtgagctta   4620

gtgagcagag agttagaaca aatctagcta ggtgtgttta aggaatattt ccattcagct   4680

agtgtagctg gattaatttc tattctccaa atcaaggatg tctagaaaat gggcattgtg   4740

gctttcaaat ctaagaagaa tctcctttgg gccagctgga tgtacaataa aaatgcttgt   4800

ttcttggcct tcctttaaaa aaaaaaaaaa aaaa                               4834


<210>  922
<211>  3475
<212>  DNA
<213>  Homo sapiens

<400>  922
gaggaggtcg gctttgttct cgccccgccc tctccccgcc tcctccctag atatcgcgag     60

agggcgggtc cgcttggctt cggcgtcgcg tcgctcctgc gctggagctc taggccggcg    120

tctctccgcg agccgcgggt caagtgccag tggctaaggg tgcgcgagta gccgccaccc    180

gttcggcgtt ggctctggcg tcggggtcgt tgtgtcgtga caaccgctgc ggtagccgtt    240

tccgaggcag cagttgcggc cgctttagcc ctgagcggga tctgcggctg cctgcgagtc    300

tctgctgtgc cgacccttct cttcgcggac cccacgccaa gcagcgaccc tgagccgaca    360

gccggagcgc ccggcaatgg cggcctcgac ggcctcgcac cggcccatca aggggatctt    420

gaagaacaag acctctacga cttcctctat ggtggcgtcg gccgaacagc cccgcgggaa    480

tgtcgacgag gagctgagca aaaaatccca gaagtgggat gaaatgaaca tcttggcgac    540

gtatcatcca gcagacaaag actatggttt aatgaaaata gatgaaccaa gcactcctta    600

ccatagtatg atgggggatg atgaagatgc ctgtagtgac accgaggcca ctgaagccat    660

ggcgccagac atcttagcca ggaaattagc tgcagctgaa ggcttggagc caaagtatcg    720

gattcaggaa caagaaagca gtggagagga ggatagtgac ctctcacctg aagaacgaga    780

aaaaaagcga caatttgaaa tgaaaaggaa gcttcactac aatgaaggac tcaatatcaa    840

actagccaga caattaattt caaaagacct acatgatgat gatgaagatg aagaaatgtt    900

agagactgca gatggagaaa gcatgaatac ggaagaatca aatcaaggat ctactccaag    960

tgaccaacag caaaacaaat tacgaagttc atagacgaga tttgttcaac actgcaattg   1020

tttgttagat gtaaaccctg tgactatagt acgttgcttc ttgttcttca caattcatga   1080

cttaagtacc aaaatgcata ccagttatta tatattgcca agaattaaat gataaactta   1140

gagactgatt agactgaaaa tgcctaatcg atatatatat tcttgtgcct agtactttac   1200

cacaaataca gtgtaatatc atcagtccaa aactgcatta cttttgtaaa aacactggtt   1260

aatttgtata agatattata gagcttttta tgctttagaa gttaaacaat atctttgggg   1320

gggaactaat ttattttcat cacttgaaat gtggtagctc ttacaaagtt tattgatttg   1380

atttttttaa aaatcaaaag ccaattgaac aacaggatat atagactgat aaatatttag   1440

gctgaatagt attttaacac ttgtcttcaa cttgatttgt ctgtttaatt gaaaagaatt   1500

ataagagtta ctgttgcatt ttctgaccta ctatttttaa aattcctgtt gagtttcttt   1560

gtgtttacaa ggaaaggact gaactttttc tcatcaaaac tagctttttt ccccacaaat   1620

aaattatcag gttaaacttt caccaatgtc tgctctgttt tttgtttttg gggggttttt   1680

tgtttgtttt tgttttttaa tgtttttggt acactgggca gacttcagag cagtttttta   1740

aaaaaataaa tattctaatg tagctatctc gccattccct ttaaatacct gtcttaacct   1800

cctgcttttc tttcctactc ctttccacac atacgcacac aatcttctac cttttaaagg   1860

atcattaaga ctgtcaccac attaggagct ctttctctca ctcttctgtc atttgctgct   1920

atgttgaaat tcttattttg accatcaatg cctatgaatt cttctaatac gtgaagaaaa   1980

tagtttgagt agcagcagtg ctataggtgg gaaatacagt ttagctgctg aatttctata   2040

cctctctgat ttacagattg ctaattaaat ggctattatt agtttggatt aattagactt   2100

aagaaaacaa ctaactgagg gttttttttg tttgtttttt gagggttttc tttgcatgag   2160

aattgtatgt aaccagtgat atgattattc ctgaatgtac agacagaagt aagcctggac   2220

attgttaaat agtccctgct ttaagggact acgataatgt gtactatgac aaacgtgctt   2280

tattcttcta acgcagtaag aattaggtgg aattttttcc ttcaaccaag tgcaggaaag   2340

ccctgtgtgt cttggtttag ttatggtttc atttctagcc atacaattga tgaattgtgt   2400

acaacttttg ttagtaccaa aataatctgt tatatgaaca gacttctaaa ataacgtctg   2460

tatattttat atatagatac atatatgaaa gaaggctttt attgaacagc ttatcttcca   2520

cttgcaggtt tatggaaaca gcagtatttg aaaataaata aaaagtggga gaattccttg   2580

ctgttagaag aatgtggcca ttattttgat tttttgaatg agatatataa tcaaagtact   2640

gctgaactgt gagtgcagta ttctaaacat ttcagctagg aataccactg atttagaaac   2700

aaaactgttt gtctctggtt tctgaattta aaatgttggg attacctgtt taaatctgtc   2760

ttgggggatg tagagattaa gtctgtacat gtgcgtgcac atatattcat gcaccctctg   2820

attttggttt tcttgtttct gagttcttag aaagtaccca catactcttt tttttttttt   2880

tgtagaagta gctgtcatag agtgaagaaa aggataagac tttaaacagt tgattctttt   2940

tgtgttttct acaaactatt ttttgaaatt taaatcacaa actcattttc tggtttttag   3000

aaagtagatg atgatttcag aggagtaagg catgccaagc agcatgctca gtggggtttt   3060

aggctgtcac atgcagctga gaaaaggtat gttcaagtca taagtaggta attgataggg   3120

tatgaactag tcaaaatatg aaccattatg attcaagtta gattttcctc tggagagaca   3180

gatctgaatg ttcagttcta gccaaggtag attttacttt caacttttta atcagtatca   3240

ctttctgtgc ttaactattt ggtgttacct tgtctgtttt catttgtcta aaattctgca   3300

gagatgacta aaatttgaca taatggtgta aatggattgt taaggtaact ttcagttgaa   3360

gattaaagca agatgccatt ttccccatga ctttggtttt gtttacattt ttccctttca   3420

gttagtatac actacacgta ctgtaataaa atacaataat atgacaaaaa aaaaa        3475


<210>  923
<211>  2223
<212>  DNA
<213>  Homo sapiens

<400>  923
acttcttttc ttggctaagc cgcgtttgta ctgtgtctta ccatgcctga accggcaaaa     60

tccgctccgg cccctaaaaa gggctccaag aaagccgtca ccaaagccca gaagaaagac    120

ggcaagaagc gcaagcgcag ccgcaaagag agctactcca tctacgtgta caaggtgctg    180

aagcaggtcc accccgacac cggcatctcg tccaaggcca tgggcatcat gaactccttc    240

gtcaacgaca tcttcgagcg catcgcggga gaggcttccc gcctggcgca ctacaacaag    300

cgctccacca tcacatcccg cgagatccag acggccgtgc gcctgctgct gcccggcgag    360

ctggccaagc acgccgtgtc cgagggcacc aaggcggtca ccaagtacac cagctccaag    420

tgagtccctg ccgggacctg gcgctcgctc gctcgagtcg ccggctgctt gactccaaag    480

gctcttttca gagccaccca cctaatcact agaaaagagc ttgttcactt attcccttag    540

tttcttttca taaagtaagt tattttagtg tgaaggtcat gggaaatggc atacgtagct    600

ttttaactat ttggaactcg aggtccccag tgcgtcattg gatttgcttt tgaatctaga    660

gcgtgtcttt actcattgtg ctgcttagcc ttcccaggag tcggttctca attaggctgt    720

tgggaatccg cctctttacc cgcccccact cccgccccac acgcgccctg gtggctcctt    780

gggtctgttt cattctaaaa cgaagtggct gagttcggct gtcatttaag agaactccag    840

gacacaattc agcccgggtt ccgcaaacac tgcgtgacag ctctgtatga ctgacgcttg    900

gcagcagctt ttgtgtccgg tcaccagttc tgccgtgcga tggggcctcc tgtggatacc    960

agccgttctg tgtattttgg acgaaggccg cgcagccggg tcccagcctt gtcctgattg   1020

ggcgacaaga atattcaaaa ttctgcgcct ttttctaatt tgtagatttc agtttccgtc   1080

gttcactttg agactttgaa attcctattt ctcattttgt tgataatttc tgcatttaat   1140

ggtctgtgct ttaaatggta acgctacggc cccaggtcac tgcgaggcac ttaccatgta   1200

gatacgggct caaaagtcac ctctcagaga cctacgtcat ccactcagga attcgcgcct   1260

ctcatacttg cctgtctcat tttatcttcc ttctagcagc tgtctgaaat tggttcgtct   1320

gttttcttgt ttatggtatt ctcaagccct tgacagaccg gctagtgtgg ttttcccgtg   1380

catcttcagc ctggcacatt atggacactt aaatactacg tattgatcta atattgttgg   1440

gttaattttt ccatcccacc cttttcttaa tcgcttccgt ggatggatga agggtgctgt   1500

tcatttccat tagatgtatg tgaaggcaca gtgaaaatgg aaatgttctt ggagctactt   1560

cctcaaaatg tatccttagt cacctcagtg caacagctgg gagggggccg tgttaagatt   1620

ttttttgcta caaagaggag gtggcaatgg tagatccacc cttatgcttc tcagtttagc   1680

ataacctctt atggattttc atcaaattca gcgtgttggt cactggaaag agccttttcc   1740

ttctcctttt cttactctcc cctcatggtg ttcccctctt aaaggagagg agcttttaat   1800

ttacacttac cacctcattt gcttttctgg aggccatgca atataggcgg gactacagag   1860

ttaatctcct ttttacaaat gaggccaaga gaagcctcat tggttcacag tcatgcagct   1920

catactgtcc acccttgtat tctcagatgc aggacaattg cattttagtt ttattttgtg   1980

gaggtgcaga atatttactc tttctgtcca acccttgatt ctgccgagga agacactgat   2040

ggtttgatga gtgattcagc tgtttttggc taagggcttt tggagctgat ggcaggggtt   2100

tgatgaatcc aaatgagctc tagacattat cacagactga atagatctta actgtctcct   2160

acatgtgtgt tttcaaatgt gtatagatgc tattgttatt aataaagtta ccaattaatt   2220

taa                                                                 2223


<210>  924
<211>  3393
<212>  DNA
<213>  Homo sapiens

<400>  924
cagtgctagc gggcgccgag cgggagccgc gcgggagcag cgcagctacg gcggcggcag     60

cggcggcgcg gttgcgattc cgagccgttg agacgcctct gcggcagctg gtggcgcagg    120

tggcttgcgt ggacgcgggt agaggcgacc ggccagcaac cgcagcgtcg gcgcccgcgg    180

ccccggcagg cgcgtcggga cgccccgagg catcctcccc cgcccgcggg cccggtagct    240

gggcccgcgt ccgccgcccg catccccgcg ccgccgcatc tcctcgccgc ctcccgggct    300

tcggaccccc ggtctcgccc ccgaaacatg actcgcgatt tcaaacctgg agacctcatc    360

ttcgccaaga tgaaaggtta tccccattgg ccagctcgag tagacgaagt tcctgatgga    420

gctgtaaagc cacccacaaa caaactaccc attttctttt ttggaactca tgagactgct    480

tttttaggac caaaggatat atttccttac tcagaaaata aggaaaagta tggcaaacca    540

aataaaagaa aaggttttaa tgaaggttta tgggagatag ataacaatcc aaaagtgaaa    600

ttttcaagtc aacaggcagc aactaaacaa tcaaatgcat catctgatgt tgaagttgaa    660

gaaaaggaaa ctagtgtttc aaaggaagat accgaccatg aagaaaaagc cagcaatgag    720

gatgtgacta aagcagttga cataactact ccaaaagctg ccagaagggg gagaaagaga    780

aaggcagaaa aacaagtaga aactgaggag gcaggagtag tgacaacagc aacagcatct    840

gttaatctaa aagtgagtcc taaaagagga cgacctgcag ctacagaagt caagattcca    900

aaaccaagag gcagacccaa aatggtaaaa cagccctgtc cttcagagag tgacatcatt    960

actgaagagg acaaaagtaa gaaaaagggg caagaggaaa aacaacctaa aaagcagcct   1020

aagaaggatg aagagggcca gaaggaagaa gataagccaa gaaaagagcc ggataaaaaa   1080

gaggggaaga aagaagttga atcaaaaagg aaaaatttag ctaaaacagg ggttacttca   1140

acctccgatt ctgaagaaga aggagatgat caagaaggtg aaaagaagag aaaaggtggg   1200

aggaactttc agactgctca cagaaggaat atgctgaaag gccaacatga gaaagaagca   1260

gcagatcgaa aacgcaagca agaggaacaa atggaaactg agcagcagaa taaagatgaa   1320

ggaaagaagc cagaagttaa gaaagtggag aagaagcgag aaacatcaat ggattctcga   1380

cttcaaagga tacatgctga gattaaaaat tcactcaaaa ttgataatct tgatgtgaac   1440

agatgcattg aggccttgga tgaacttgct tcacttcagg tcacaatgca acaagctcag   1500

aaacacacag agatgattac tacactgaaa aaaatacggc gattcaaagt tagtcaggta   1560

atcatggaaa agtctacaat gttgtataac aagtttaaga acatgttctt ggttggtgaa   1620

ggagattccg tgatcaccca agtgctgaat aaatctcttg ctgaacaaag acagcatgag   1680

gaagcgaata aaaccaaaga tcaagggaag aaagggccaa acaaaaagct agagaaggaa   1740

caaacagggt caaagactct aaatggagga tctgatgctc aagatggtaa tcagccacaa   1800

cataacgggg agagcaatga agacagcaaa gacaaccatg aagccagcac gaagaaaaag   1860

ccatccagtg aagagagaga gactgaaata tctctgaagg attctacact agataactag   1920

gttgacatac ctggaatata gagaacactt gagaagtttg taatggtttt catttgaaat   1980

agactgctga aagttttaaa tttttataag cataggtttg atgttgaaaa cttgttttga   2040

gggagaaaat ccctttgttt taaagtaaag taaacattat cgctaagtgt acttgtgcag   2100

tattaacagc tacattatac agtaaatgtg ggataaaatc catttagaaa atgttaaact   2160

gcttttccag acatggttgt agcatatttt caattagtgt gtgtatgtta atgtgtaatt   2220

gatagtagaa caaagttaca tttttaaaac tgctacttgt ataaaccttg cctcttttcc   2280

caaatactgt gggttttgtg catagttttt acaaaccttg gatttaccag actgtctttt   2340

cactgtttgt gggttttgta gaagttacac atttttatgg tagataaaat gttacttcta   2400

tacaagtact cactcccttt ttatcaaaag ttaattttaa tctcacagtc tacattgtgc   2460

tacattatcc agcttctttg gaacaatgtg tgctctgtat ggtttttttt ggtatgacaa   2520

ctaattaagc aactgacatg gaactgagaa ttctacaaac tataaaacat taatttttga   2580

aggtaattta gttttgtggc tgggcattca gtgaagtctt aggacttctt tgcagacaac   2640

tgactgggta tatataggaa tgaatctggc tttagggtta aatcatttaa ggtcctttta   2700

taggcaggca ctagtaacta aaactgaaaa ctaagtaagt ttatttttga ggaatgttgt   2760

taaaaatgtc tttaggaagt cactaaaact taattggaag aaaaaatcat gatgcttata   2820

caataaatat gaataaatgt tatataagga aactcaccta tttgaaatca tggctatatt   2880

gtttttattt tctagattcc aaaaatacaa acactagttg ttccagcatt gtactttgat   2940

aagtctgtac attgacgtgt atggactaaa tccagggtaa aatcaatgtt acaaaattta   3000

agggtatgtt aactaaagga tagcatttct aagatatttt gaatattagg gtcatttggc   3060

acttctcagc aagtaggata cttctcatgt tttgaaatta tatgaatatg gaaaaaaatg   3120

gcttaagacc agcgtctctg tatgacattg tgtggttgac cctctgagat aactgttttc   3180

atctacagaa ttgcattttt gcttttaaag aggtcttata atggaactag gaatcaccgt   3240

tttgagagaa cctgcatata taccagtcat tatctgtttg gtccttatac agttttaact   3300

tacttagatt tattctagtt aagccataag ttcaacgtgt aaacttgttt tcattaaaga   3360

atttttctat caaaaaaaaa aaaaaaaaaa aaa                                3393


<210>  925
<211>  2618
<212>  DNA
<213>  Homo sapiens

<400>  925
cctctcagag ccccagtcgc gcgccccttc ttggttcgct cggtgcccgc gcaggcccct     60

cgggcggtgg cgaggaggcg cccaggcgga ggcggcggcg ggcggaggag cgcaggagcg    120

ggcggccagg ccaccgcgcg gcggcggagc gggccgcggc ccggcgctcc ttccccaccg    180

cggcccgacg caccccggcc gccgccatga gcggctcctc aggcaccccg tatctgggca    240

gcaagatcag cctcatctcc aaggcgcaga tccgctacga gggcattctc tacaccatcg    300

acaccgacaa ctccaccgtg gcgctcgcca aagtgaggtc ctttggcact gaagaccgtc    360

ccacagatag gcctgcgccc cccagagagg agatttatga gtacatcatt ttccgaggaa    420

gtgacatcaa ggatatcact gtgtgtgaac ctccgaaagc tcagcacaca ctcccgcagg    480

atcccgccat tgttcagtct tccctgggtt ctgcctccgc ctcgcccttc cagccgcacg    540

tgccttacag ccctttccga gggatggcgc cctacggccc gctggcggcc agctccctgc    600

tcagccagca gtatgccgcc tccctgggtc taggagctgg ttttccatcc atcccagtcg    660

gcaagagccc catggtggag caggctgtgc agactggttc tgctgacaac ctgaatgcta    720

aaaagctgtt acctggcaag ggcaccacag ggacgcagct caacggtcgt caggcccagc    780

cgagcagcaa gacggccagc gatgtagtcc agccggcagc tgtgcaagct caagggcagg    840

tgaatgacga gaacagaaga cctcagagga ggcgatcagg aaacaggcga acaaggaatc    900

gctccagagg gcaaaaccgt ccaactaacg ttaaggaaaa cacaatcaaa tttgagggtg    960

actttgattt cgagagtgca aatgcccagt tcaaccgaga ggagcttgac aaagaattta   1020

agaagaaact gaattttaaa gatgacaagg ctgagaaggg ggaagagaag gacctggctg   1080

tggtgaccca gagtgccgaa gcgcccgctg aggaagacct tctggggccc aactgctact   1140

atgacaaatc caagtcgttc ttcgacaaca tctcttctga actcaagacc agctccaggc   1200

ggacgacgtg ggccgaagag aggaagctca acacagagac ctttggggtg tcagggaggt   1260

ttcttcgtgg ccgcagttct cggggcggat tccgaggagg caggggcaat gggaccaccc   1320

gtcgcaaccc cacttcccac agggccggga ctggcagggt gtgagggtgc agccaaaggc   1380

tcctactgaa gtggcgcata actgacgctg tgtgtgtcag gacgcgagga aaacgctgca   1440

cttacaggga gaggtggtca ctttgtttac ggagtttgga agagacccat actgctactt   1500

gtgttttgga cttaactgaa cttggacatg gtctgagtta gaaccacttg ttttggggaa   1560

gtattcatgg gtaacctctt tgaggtctct ttatctgtgt ttccttttta gttgcgcata   1620

gcctaattct aaggttttgg tattttgcaa aaaggtttct atagtgaaag ctgaatcctt   1680

actttgtgac tttttttttt ttttttaatg acaagctttg acttttaaaa gtggaaccaa   1740

atctgttggc agaggtggca gccaagtaca tctctgtaac ccagctggcc cctggtgctg   1800

ttggcctggc accccactgc caagggtggg gtctcaggag tcaggcaggg ccagcacagg   1860

gtggcgtggg gggcaggggt gggtgggtgg agggcacgga aggggttttc ccatggatca   1920

tgttgtataa gtgaaccaga ccaccctgat ggcatccaca gtgatgtcaa ggttggggct   1980

ggccaggggt gggtggacta gaagcatttg ggagtagtgg ccaggggccc tggacgctag   2040

ccacggagct gctgcacaga gcctggtgtc cacaagcttc caggttgggg ttggagcctg   2100

ggatgagccc cggcagcgcc ttggcccttc tgtggtccct gccagcctct gacctgggcc   2160

ggtcagtcat tgctggactc tggccacaca ctggcgttct catccacttg gaaacaagcc   2220

agtcttttct gcaaggtcag ttgaccaaga gcatatttcc cctctgttgt acatcgttgt   2280

tttgtgtttg tgttgtaaca gtgggtggag ggagggtggg gtctacattt gttgcatgag   2340

tcgatgggtc agaactttag tatacgcatg cgtcctctga gtgacagggc attttgtcga   2400

aaataagcac cttggtaact aaacccctct aatagctata aaggctttag ttctgtattg   2460

attaagttac tgtaaaagct tgggtttatt tttgtaggac ttaatggcta agaattagaa   2520

catagcaagg gggctcctct gttggagtaa tgtaaattgt aattataaat aaacatgcaa   2580

acctttaaaa ttttaaaaaa aaaaaaaaaa aaaaaaaa                           2618


<210>  926
<211>  4049
<212>  DNA
<213>  Homo sapiens

<400>  926
agcgcgtacc actctggcgc tcccgaggcg gcctcttgtg cgatccaggg cgcacaaggc     60

tgggagagcg ccccggggcc cctgctatcc gcgccggagg ttggaagagg gtgggttgcc    120

gccgcccgag ggcgagagcg ccagaggagc gggaagaagg agcgctcgcc cgcccgcctg    180

cctcctcgct gcctccccgg cgttggctct ctggactcct aggcttgctg gctgctcctc    240

ccacccgcgc ccgcctcctc actcgccttt tcgttcgccg gggctgcttt ccaagccctg    300

cggtgcgccc gggcgagtgc ggggcgaggg gcccggggcc agcaccgagc agggggcggg    360

ggtccgggca gagcgcggcc ggccggggag gggccatgtc tggcgcgggc gcagcggggc    420

ccgtctgcag caagtgaccg agcggcgcgg acggccgcct gccccctctg ccacctgggg    480

cggtgcgggc ccggagcccg gagcccgggt agcgcgtaga gccggcgcga tgcacgtgcg    540

ctcactgcga gctgcggcgc cgcacagctt cgtggcgctc tgggcacccc tgttcctgct    600

gcgctccgcc ctggccgact tcagcctgga caacgaggtg cactcgagct tcatccaccg    660

gcgcctccgc agccaggagc ggcgggagat gcagcgcgag atcctctcca ttttgggctt    720

gccccaccgc ccgcgcccgc acctccaggg caagcacaac tcggcaccca tgttcatgct    780

ggacctgtac aacgccatgg cggtggagga gggcggcggg cccggcggcc agggcttctc    840

ctacccctac aaggccgtct tcagtaccca gggcccccct ctggccagcc tgcaagatag    900

ccatttcctc accgacgccg acatggtcat gagcttcgtc aacctcgtgg aacatgacaa    960

ggaattcttc cacccacgct accaccatcg agagttccgg tttgatcttt ccaagatccc   1020

agaaggggaa gctgtcacgg cagccgaatt ccggatctac aaggactaca tccgggaacg   1080

cttcgacaat gagacgttcc ggatcagcgt ttatcaggtg ctccaggagc acttgggcag   1140

ggaatcggat ctcttcctgc tcgacagccg taccctctgg gcctcggagg agggctggct   1200

ggtgtttgac atcacagcca ccagcaacca ctgggtggtc aatccgcggc acaacctggg   1260

cctgcagctc tcggtggaga cgctggatgg gcagagcatc aaccccaagt tggcgggcct   1320

gattgggcgg cacgggcccc agaacaagca gcccttcatg gtggctttct tcaaggccac   1380

ggaggtccac ttccgcagca tccggtccac ggggagcaaa cagcgcagcc agaaccgctc   1440

caagacgccc aagaaccagg aagccctgcg gatggccaac gtggcagaga acagcagcag   1500

cgaccagagg caggcctgta agaagcacga gctgtatgtc agcttccgag acctgggctg   1560

gcaggactgg atcatcgcgc ctgaaggcta cgccgcctac tactgtgagg gggagtgtgc   1620

cttccctctg aactcctaca tgaacgccac caaccacgcc atcgtgcaga cgctggtcca   1680

cttcatcaac ccggaaacgg tgcccaagcc ctgctgtgcg cccacgcagc tcaatgccat   1740

ctccgtcctc tacttcgatg acagctccaa cgtcatcctg aagaaataca gaaacatggt   1800

ggtccgggcc tgtggctgcc actagctcct ccgagaattc agaccctttg gggccaagtt   1860

tttctggatc ctccattgct cgccttggcc aggaaccagc agaccaactg ccttttgtga   1920

gaccttcccc tccctatccc caactttaaa ggtgtgagag tattaggaaa catgagcagc   1980

atatggcttt tgatcagttt ttcagtggca gcatccaatg aacaagatcc tacaagctgt   2040

gcaggcaaaa cctagcagga aaaaaaaaca acgcataaag aaaaatggcc gggccaggtc   2100

attggctggg aagtctcagc catgcacgga ctcgtttcca gaggtaatta tgagcgccta   2160

ccagccaggc cacccagccg tgggaggaag ggggcgtggc aaggggtggg cacattggtg   2220

tctgtgcgaa aggaaaattg acccggaagt tcctgtaata aatgtcacaa taaaacgaat   2280

gaatgaaaat ggttaggacg ttacagatat attttcctaa acaatttatc cccatttctc   2340

ggtttatcct gatgcgtaaa cagaagctgt gtcaagtgga gggcggggag gtccctctcc   2400

attccctaca gttttcatcc tgaggcttgc agaggcccag tgtttaccga ggtttgccca   2460

aatccaagat ctagtgggag gggaaagagc aaatgtctgc tccgaggagg gcggtgtgtt   2520

gatctttgga ggaaaaatat gttctgttgt tcagctggat ttgccgtggc agaaatgaaa   2580

ctaggtgtgt gaaatacccg cagacatttg ggattggctt ttcacctcgc cccagtggta   2640

gtaaatccat gtgaaattgc agaggggaca aggacagcaa gtaggatgga acttgcaact   2700

caaccctgtt gttaagaagc accaatgggc cgggcacagt agctcccacc tgtaatccca   2760

gcactttggg aggctgaggt gggcggatca tttgaggtca ggagttcgag accagcctgg   2820

ccaacatggt gaaaccccat ctctactaaa aatacaaaaa ttagccgggc atggtggcac   2880

gcacctgtaa tcccagctac tctggaggct gaggcaggag aattgcttga accccagagg   2940

tggaggttgc agtgagccaa gatcgtccca ctgcactcca gcttgggtga caaaacaaga   3000

ctccatctca aaagaaaaaa aaaacagcac caatgaagcc tagttctcca cgggagtggg   3060

gtgagcagga gcactgcaca tcgccccagt ggaccctctg gtctttgtct gcagtggcat   3120

tccaaggctg ggccctggca agggcacccg tggctgtctc ttcatttgca gaccctgatc   3180

agaagtctct gcaaacaaat ttgctccttg aattaagggg gagatggcat aataggaggt   3240

ctgatgggtg caggatgtgc tggacttaca ttgcaaatag aagccttgtt gagggtgaca   3300

tcctaaccaa gtgtcccgat ttggaggtgg catttctgac gtggctcttg gtgtaagcct   3360

gccttgcctt ggctggtgag tcccataaat agtatgcact cagcctccgg ccacaaacac   3420

aaggcctagg ggagggctag actgtctgca aacgttttct gcatctgtaa agaaaacaag   3480

gtgatcgaaa actgtggcca tgtggaaccc ggtcttgtgg gggactgttt ctccatcttg   3540

actcagacag ttcctggaaa caccggggct ctgtttttat tttctttgat gtttttcttc   3600

tttagtagct tgggctgcag cctccactct ctagtcactg gggaggagta ttttttgtta   3660

tgtttggttt catttgctgg cagagctggg gctttttgtg tgatccctct tggtgtgagt   3720

tttctgaccc aaccagcctc tggttagcat catttgtaca tttaaacctg taaatagttg   3780

ttacaaagca aagagattat ttatttccat ccaaagctct tttgaacacc cccccccctt   3840

taatccctcg ttcaggacga tgagcttgct ttccttcaac ctgtttgttt tcttatttaa   3900

gactatttat taatggttgg accaatgtac tcacagctgt tgcgtcgagc agtccttagt   3960

gaaaattctg tataaataga caaaatgaaa agggtttgac cttgcaataa aaggagacgt   4020

ttggttctgg caaaaaaaaa aaaaaaaaa                                     4049


<210>  927
<211>  3408
<212>  DNA
<213>  Homo sapiens

<400>  927
acatctcccg gcaggctgcg gaagggggtc gagtagaagg accgccgctc cggcctcccg     60

cgacttctcg aaggtgggca ggtcccacct tgtggaggat ggaggtgacc ggggacgccg    120

gggtaccaga atctggcgag atccggactc taaagccgtg tctgctgcgc cgcaactaca    180

gccgcgaaca gcacggcgtg gccgcctcct gcctcgaaga cctgaggagc aaggcctgtg    240

acattctggc cattgataag tccctgacac cagtcaccct ggtcctggca gaggatggca    300

ccatagtgga tgatgacgat tactttctgt gtctaccttc caatactaag tttgtggcat    360

tggctagtaa tgagaaatgg gcatacaaca attcagatgg aggtacagct tggatttccc    420

aagagtcctt tgatgtagat gaaacagaca gcggggcagg gttgaagtgg aagaatgtgg    480

ccaggcagct gaaagaagat ctgtccagca tcatcctcct atcagaggag gacctccaga    540

tgcttgttga cgctccctgc tcagacctgg ctcaggaact acgtcagagt tgtgccaccg    600

tccagcggct gcagcacaca ctccaacagg tgcttgacca aagagaggaa gtgcgtcagt    660

ccaagcagct cctgcagctg tacctccagg ctttggagaa agagggcagc ctcttgtcaa    720

agcaggaaga gtccaaagct gcctttggtg aggaggtgga tgcagtagac acgggtatca    780

gcagagagac ctcctcggac gttgcgctgg cgagccacat ccttactgca ctgagggaga    840

agcaggctcc agagctgagc ttatctagtc aggatttgga ggtgggcgga aaccagggtc    900

actgagctac agaggaggac atgccctggg atgtagtagt atcatgcaga ggtgtgtggg    960

cccttttgtt cacctctgca gactgtgaat cctagctgcc agtttgccta ttatatgcca   1020

aggcatttgc aaaaatctca ttaatctaaa tcaaaatagc tttaaagaaa aatgcataca   1080

cttcctcaga tcatcaaaca gactctggtc caaggttggt aatgaaatga ctgttcctga   1140

cagggaggaa tagcagggcc caatcttctg agatggcttc tgggtctttc catggtcaga   1200

gaagatctat agtccgtcct gaggtctgtc aatgtcacag gaaaaggcaa acttgagggg   1260

atcgtcgcct gctggctaag accagggagc taaaaacttg aggaagggaa cctgcctggg   1320

tgggtgctac ttctgattca ttgtccttgt ccctgtcata agtacctccc tattgtagat   1380

agaagggaag gaaactgttg acttgagctt ggctaaattt cctgaaggtg gaggacctta   1440

gagttgctcc aagtaaactt tccaaggact tcttcctgtt ggtgttgtaa gaaaaggccc   1500

atgcttgtcc gggcacagtg gcttacgcct gttaatgcca gtactttggg aggccgaggc   1560

aggtggatca cctgaggtca ggagttcgag accagcctga ccaacatggc gaaaccccat   1620

ctctactaaa aatacaaaaa ttagcctggc atggtggtgg gaggctgaag caagagaatc   1680

acttgaaccc aggaggtgga ggttgcgtga gctaagatcg cgccactgca ctccagcctg   1740

ggcgacaaga gtgaaactcc gtcttaaaaa agcccatggc aggctgggcg cggtggctca   1800

cgcctgtaat cccagcactt tgggaggcca aggtgggcgg atcacaaggt caggagatcg   1860

agaccatcct ggcgaacacg gtgaaacccc gtctctacta aaaaaaatac aaaaaaatta   1920

gccaggcgtg gtcgtgggca cctgtagtcc cagctactca gggggctgag gcaggagaat   1980

ggcgtgaatc cgggaggcgg agcttgcagg gagccgagat agtgtcactg cactccagcc   2040

tgggtgacag agcgagactc cgtctcaaaa aacaaaaagc ccgtggcaat taatggtaaa   2100

ggaaacccgg catttcagtg taaagaggta acataaacgg atactgcctc attgcactcc   2160

ccaaaagaga gtcaggagag cagcaggaga ggcgcacaga aggcccagtt ctcaggggtt   2220

tttattcttg ctgcagttgg ttaccaagga agaccccaaa gcactggctg ttgccttgaa   2280

ctgggacata aagaagacgg agactgttca ggaggcctgt gagcgggagc tcgccctgcg   2340

cctgcagcag acgcagagct tgcattctct ccggagcatc tcagcaagca aggcctcacc   2400

acctggtgac ctgcagaatc ctaagcgagc cagacaggat cccacatagc agcagcggga   2460

agtgtgccaa ggaagctctg tggcgttgtg ttattggtag acaccctcag cctcatcatt   2520

tgactaccta tgtactactc taccccctgc cttagagcac cttccagaga agctattcca   2580

ggtctcaaca tacgccgttc caccaatttt ttttttagcc ccaccagctt caggacttct   2640

gccaattttg aatgatatag ctgcaccaac aatatcccgc ctcctctaat tacatatgat   2700

gttctctgtt caaaagtaat tggcagtgat tggccaggcg cagtggctca cgcctgtaat   2760

cccagcactg ggaggccgag gggggcggat cgtgaagtca ggagatcgag accatcctgg   2820

ctaacatggt gaaaccctgt ctctactaaa aatacaaaaa aaattagcca gccatggtgg   2880

cgggcgcctg taatcccagc tacttgggag gctgaggcag gagaatggca tgaacctggg   2940

aggcagagct tgcagtgagc tgagattgcg ccactgcact ccagcctggg caacagagcg   3000

agactccgtc tcaaaaaaaa aaaaaaaaaa agtaattggc agtgactatg ggcgcactgc   3060

ctaacattta gccctgcccc atatggaaca tgttaaaaaa aaaaaaagcc aggccgagcg   3120

tgttggctca cgcttgtaat cccagcactt tgggaggccg aggcgggtgg atcacgaggt   3180

caggagatcg agaccatcct ggctaacaca gtgaaacgtg tttttactaa aagtacaaaa   3240

aactagctgg gcgtggtggc aggagcctgt agtcccagct actcgggagg ctgaggcagg   3300

agaattgctt gaaccgggga ggcagaagtt gcagtgagcc gagattatgc cactgtactc   3360

cagcctgggt gacagagtga cactctgtct caaaaaaaaa aaaaaaaa                3408


<210>  928
<211>  3780
<212>  DNA
<213>  Homo sapiens

<400>  928
gtgctggggc caagcaggca ttaaactcta cccatcaaga caaaatgcct agacttgttc     60

agaccccaaa tctaagccac ctttcttact ggaaaagtcc atggaaccat ctctcaagta    120

tatcaacaag aaatttccca acatagatgt ccgaaacagc acgcaacatt taggaccagt    180

acatcgtgaa aaagccgaga taattagatt cctcaccaac tactaccagt catttgtgga    240

tgtcatggaa tttcgggatc atgtatatga acttctcaac accattgatg cctgccagtg    300

ccattttgat atcaatctca actttgattt cactcggagt tacctggact tgattgtaac    360

ttacacctca gtcattttac ttctgtcacg gattgaagat cggcggatac tcattggcat    420

gtacaattgt gcccatgaga tgctgcatgg gcatggtgac cccagttttg cccgtctggg    480

tcagatggtc ttggagtatg accaccctct gaagaagctg acagaagagt ttgggcctca    540

cacaaaggct gtgagtggag ccctcctctc tttgcatttc ctctttgtcc gaagaaacca    600

gggggctgag cagtggcgca gtgcccaact tctaagcctc atcagcaacc ccccagccat    660

gattaaccct gctaattcag atacaatggc ctgtgagtat ctgtctgtgg aagtaatgga    720

gcgctggatt atcattgggt ttcttctttg tcatgggtgc ctcaactcca atagccagtg    780

ccagaagctg tggaagctgt gtctgcaggg ctccctctac atcaccctta tccgtgagga    840

tgtgctgcag gtgcacaaag tcaccgagga cctgtttagc agtttgaaag ggtatggcaa    900

gagagtggca gacataaagg agagcaagga acatgtaatt gcaaacagtg gccagtttca    960

ttgtcaacgg cggcaatttc tgcggatggc agtgaaggag ctggagactg tgttggctga   1020

tgaaccggga ctactgggtc ctaaggctct ttttgctttc atggccctgt ccttcattcg   1080

tgatgaggtc acctggctgg ttcgccacac agagaatgtc accaagacaa agacacctga   1140

ggactatgct gactcgagca ttgcagagct acttttcttg ttggagggga ttaggtctct   1200

ggtccgaaga cacatcaaag tgatacagca ataccacctt cagtacttgg caagatttga   1260

tgctcttgtg ctcagtgaca tcattcagaa cttgtctgtg tgtccagagg aggagtccat   1320

catcatgtcc tcattcgtca gtatcctctc ctctctgaat ctcaaacaag ttgataatgg   1380

agaaaaattt gaattctcag gattgaggct ggactggttc cgcctacagg catacactag   1440

cgtggctaag gcccctctgc acctgcatga gaaccctgac ttagccaagg tgatgaacct   1500

cattgtcttc cactcccgaa tgctggactc cgtagaaaaa ttgctggtgg aaacttctga   1560

tctgtctact ttctgctttc atcttcgtat ctttgagaag atgtttgcca tgaccttgga   1620

ggaatctgcc atgttgcgtt atgccattgc tttccccctg atttgtgctc actttgtcca   1680

ctgcactcat gagatgtgcc cagaggagta cccccacctc aagaaccatg gtcttcacca   1740

ctgcaactcc ttcctggaag agttggccaa gcagaccagc aattgcgtcc tggagatctg   1800

tgctgagcag cgaaacctga gcgagcagct tctacctaag cactgtgcca ctacaatcag   1860

caaagccaag aacaagaaaa ccaggaagca gaggcagact cccagaaaag gagagcccga   1920

gagggacaag ccaggagctg agagtcaccg gaagaaccgc agcattgtca ccaacatgga   1980

caagctacac ctaaacttga cagaactggc actgacaatg aatcatgtat acagtttctc   2040

cgtgtttgaa catactatct tcccttctga gtacctcagc agccacctgg aggccagact   2100

caacagagcc attgtgtggc tggctggcta caatgccacg acccaggaga tcgtacggcc   2160

ttctgagctg ttggcaggag tcaaagcata cattggtttc atacagtcac tggcccagtt   2220

tttgggtgca gatgcttcca gagtcatccg caacgccctc ctgcagcaga cacaaccact   2280

ggattcctgt ggggaacaga caatcaccac actctacaca aactggtacc tggaaagtct   2340

gcttagacag gcaagcagtg ggaccatcat cctctcccca gccatgcagg ccttcgtcag   2400

cctgcccaga gaaggggagc agaacttcag tgcagaggag ttctctgaca tctctgagat   2460

gcgggccttg gcagaactcc tgggccccta tggcatgaag ttcctgagtg aaaacctgat   2520

gtggcatgtg acctctcaga ttgtggagct gaagaagctg gtggtggaaa acatggacat   2580

acttgttcag atcagatcca actttagcaa gccggacttg atggcttccc tgctgcccca   2640

gctgacaggg gctgaaaatg tgctaaagcg catgaccatc attggggtta tcctcagttt   2700

cagggccatg gcccaagagg gacttcggga ggttttctcc tcccactgcc catttcttat   2760

gggtcccatt gagtgcttga aggagtttgt cactccagac acagacatca aggtgacctt   2820

gagtatcttt gagctggcat ctgctgcagg tgtgggctgt gacattgacc cagccttggt   2880

ggctgccatt gctaatctga aagctgatac ttcatctcct gaggaggaat ataaggtggc   2940

ctgcctgctc ttgatctttc tggcagtttc cctcccactc cttgccactg acccttcttc   3000

cttttatagc attgagaagg atggttacaa caacaatatt cattgcttga ccaaagccat   3060

catccaggtg tctgctgccc tcttcacgct ctacaacaag aacattgaaa ctcacctcaa   3120

ggaatttctg gtggtggcct ctgtcagcct cttgcagctg ggccaggaga ctgacaagct   3180

taaaaccaga aatcgagaat ccatttctct gctcatgcgc ttggtggtgg aggagtcatc   3240

cttcctgacc ctggacatgc tggagtcctg tttcccttat gtcctgcttc gaaatgccta   3300

tcgggaggtg tctcgggcct tccacctaaa ctgaatgcct gccagtaccc actgaagagc   3360

cctttggacc ttcctaaacc cttgccatag tggaagctgt ggtcactttc gcagggggtg   3420

ggaatggggt ggggtcacta aggagagagg gtcaggagcc agagttgatg agcagatctg   3480

tggaagaaca atccagggct gagaaatcgt agagcagtga ggcaggctgg gagcatggag   3540

gacagcttat ggaaaaagtt agggcgtggg gccacatgtg tgaattttac aatgaaaaaa   3600

ggagtaacgt acaagtatat tttctatctt ctggtgactt gagcttgagc tctgacaggc   3660

atgggcctct ccgaccttca tcactattct taggataatg ctggcgggca gagatgatca   3720

atcatcatat taaatcataa tgagcttata atcctcccac tggaaaaaaa aaaaaaaaaa   3780


<210>  929
<211>  1963
<212>  DNA
<213>  Homo sapiens

<400>  929
gaggctataa gagggcgcac aagtggcgcg gcgcaggagc cgccgccagt ggagggccgg     60

gcgctgcggc cgcggccggg gcgggcgcag ggccgagcgg acgggggggc gcgggccccc    120

cgggaggccg cggccactcc cccccgggcc ggcgcggcgg gggaggcgga ggatggaaac    180

acccttctac ggcgatgagg cgctgagcgg cctgggcggc ggcgccagtg gcagcggcgg    240

cagcttcgcg tccccgggcc gcttgttccc cggggcgccc ccgacggccg cggccggcag    300

catgatgaag aaggacgcgc tgacgctgag cctgagtgag caggtggcgg cagcgctcaa    360

gcctgcggcc gcgccgcctc ctacccccct gcgcgccgac ggcgccccca gcgcggcacc    420

ccccgacggc ctgctcgcct ctcccgacct ggggctgctg aagctggcct cccccgagct    480

cgagcgcctc atcatccagt ccaacgggct ggtcaccacc acgccgacga gctcacagtt    540

cctctacccc aaggtggcgg ccagcgagga gcaggagttc gccgagggct tcgtcaaggc    600

cctggaggat ttacacaagc agaaccagct cggcgcgggc gcggccgctg ccgccgccgc    660

cgccgccgcc ggggggccct cgggcacggc cacgggctcc gcgccccccg gcgagctggc    720

cccggcggcg gccgcgcccg aagcgcctgt ctacgcgaac ctgagcagct acgcgggcgg    780

cgccgggggc gcggggggcg ccgcgacggt cgccttcgct gccgaacctg tgcccttccc    840

gccgccgcca cccccaggcg cgttggggcc gccgcgcctg gctgcgctca aggacgagcc    900

acagacggtg cccgacgtgc cgagcttcgg cgagagcccg ccgttgtcgc ccatcgacat    960

ggacacgcag gagcgcatca aggcggagcg caagcggctg cgcaaccgca tcgccgcctc   1020

caagtgccgc aagcgcaagc tggagcgcat ctcgcgcctg gaagagaaag tgaagaccct   1080

caagagtcag aacacggagc tggcgtccac ggcgagcctg ctgcgcgagc aggtggcgca   1140

gctcaagcag aaagtcctca gccacgtcaa cagcggctgc cagctgctgc cccagcacca   1200

ggtgcccgcg tactgagtcc gcgcgcgggg cgcatgcgcg gccaccctcc ccaaggggcg   1260

ggctcgcggg ggggtgtcgt gggcgccccg gacttggaga gggtgcggcc ctggggaccc   1320

cccctccccg agtgtgccca ggaactcaga gagggcgcgg cccccgggga ttcccccccc   1380

ccgagggtgc ccaggactcg acaagctgga ccccctgctc ccgggggggc gagcgcatga   1440

cccccccgcc ctcgcgctgc ctctttcccc cgcgcggccg ccccgtgttg cacaaacccg   1500

cgcgtctcgg ctgccccttt gtacaccgcg ccgcggaagg gggctccgag ggggcgcagc   1560

ctcaaaccct gcctttcctt tacttttact tttttttttt tttctttgga agagagaaga   1620

acagagtgtt cgattctgcc ctatttatgt ttctactcgg gaacaaacgt tggttgtgtg   1680

tgtgtgtgtt ttcttgtgtt ggttttttaa agaaatggga agaagaaaaa aaaattctcc   1740

gcccctttcc tcgatctcgc tccccccttc ggttctttcg accggtcccc cctccctttt   1800

ttgttctgtt ttgttttgtt ttgctacgag tccacattcc tgtttgtaat ccttggttcg   1860

cccggttttc tgttttcagt aaagtctcgt tacgccagct cggctctccg cctccttctt   1920

cccccgccgg ggcctggcgg gctgggcggg gcctggttcg ctt                     1963


<210>  930
<211>  1291
<212>  DNA
<213>  Homo sapiens

<400>  930
tggtcaccag ggaagctggc aagggaaggg agactagggt gcgctctagg agaagccgac     60

agcctgagag tcccagaaga ggagccctgt ggaccctccc ctgccagcca ctcccttacc    120

ctgggtataa gagccaccac cgcctgccat ccgccaccat ctcccactcc tgcagctctt    180

ctcacaggac cagccactag cgcagcctcg agcgatggcc tatgtccccg caccgggcta    240

ccagcccacc tacaacccga cgctgcctta ctaccagccc atcccgggcg ggctcaacgt    300

gggaatgtct gtttacatcc aaggagtggc cagcgagcac atgaagcggt tcttcgtgaa    360

ctttgtggtt gggcaggatc cgggctcaga cgtcgccttc cacttcaatc cgcggtttga    420

cggctgggac aaggtggtct tcaacacgtt gcagggcggg aagtggggca gcgaggagag    480

gaagaggagc atgcccttca aaaagggtgc cgcctttgag ctggtcttca tagtcctggc    540

tgagcactac aaggtggtgg taaatggaaa tcccttctat gagtacgggc accggcttcc    600

cctacagatg gtcacccacc tgcaagtgga tggggatctg caacttcaat caatcaactt    660

catcggaggc cagcccctcc ggccccaggg acccccgatg atgccacctt accctggtcc    720

cggacattgc catcaacagc tgaacagcct gcccaccatg gaaggacccc caaccttcaa    780

cccgcctgtg ccatatttcg ggaggctgca aggagggctc acagctcgaa gaaccatcat    840

catcaagggc tatgtgcctc ccacaggcaa gagctttgct atcaacttca aggtgggctc    900

ctcaggggac atagctctgc acattaatcc ccgcatgggc aacggtaccg tggtccggaa    960

cagccttctg aatggctcgt ggggatccga ggagaagaag atcacccaca acccatttgg   1020

tcccggacag ttctttgatc tgtccattcg ctgtggcttg gatcgcttca aggtttacgc   1080

caatggccag cacctctttg actttgccca tcgcctctcg gccttccaga gggtggacac   1140

attggaaatc cagggtgatg tcaccttgtc ctatgtccag atctaatcta ttcctggggc   1200

cataactcat gggaaaacag aattatcccc taggactcct ttctaagccc ctaataaaat   1260

gtctgagggt gtctcatgaa aaaaaaaaaa a                                  1291


<210>  931
<211>  4099
<212>  DNA
<213>  Homo sapiens

<400>  931
agccagccct tgccgtggcc ggagccgagc ggcgcatccg ggccggagaa gaggacgacg     60

acgaggtcct cgaagtggac ccgtttgcga agcgccaggg agaaggagga gcggacgcat    120

cgtagaaagg ggtggtggcg cccgaccccg cgccccggcc cgaagctctg agggcttccc    180

ggcccccact gcctgcggca tggcccgggg ctcggcgctc ccgcggcggc cgctgctgtg    240

catcccggcc gtctgggcgg ccgccgcgct tctgctctca gtgtcccgga cttcaggtga    300

agtggaggtt ctggatccga acgacccttt aggacccctt gatgggcagg acggcccgat    360

tccaactctg aaaggttact ttctgaattt tctggagcca gtaaacaata tcaccattgt    420

ccaaggccag acggcaattc tgcactgcaa ggtggcagga aacccacccc ctaacgtgcg    480

gtggctaaag aatgatgccc cggtggtgca ggagccgcgg cggatcatca tccggaagac    540

agaatatggt tcacgactgc gaatccagga cctggacacg acagacactg gctactacca    600

gtgcgtggcc accaacggga tgaagaccat taccgccact ggcgtcctgt ttgtgcggct    660

gggtccaacg cacagcccaa atcataactt tcaggatgat taccacgagg atgggttctg    720

ccagccttac cggggaattg cctgtgcacg cttcattggc aaccggacca tttatgtgga    780

ctcgcttcag atgcaggggg agattgaaaa ccgaatcaca gcggccttca ccatgatcgg    840

cacgtctacg cacctgtcgg accagtgctc acagttcgcc atcccatcct tctgccactt    900

cgtgtttcct ctgtgcgacg cgcgctcccg gacacccaag ccgcgtgagc tgtgccgcga    960

cgagtgcgag gtgctggaga gcgacctgtg ccgccaggag tacaccatcg cccgctccaa   1020

cccgctcatc ctcatgcggc ttcagctgcc caagtgtgag gcgctgccca tgcctgagag   1080

ccccgacgct gccaactgca tgcgcattgg catcccagcc gagaggctgg gccgctacca   1140

tcagtgctat aacggctcag gcatggatta cagaggaacg gcaagcacca ccaagtcagg   1200

ccaccagtgc cagccgtggg ccctgcagca cccccacagc caccacctgt ccagcacaga   1260

cttccctgag cttggagggg ggcacgccta ctgccggaac cccggaggcc agatggaggg   1320

cccctggtgc tttacgcaga ataaaaacgt acgcatggaa ctgtgtgacg taccctcgtg   1380

tagtccccga gacagcagca agatggggat tctgtacatc ttggtcccca gcatcgcaat   1440

tccactggtc atcgcttgcc ttttcttctt ggtttgcatg tgccggaata agcagaaggc   1500

atctgcgtcc acaccgcagc ggcgacagct gatggcctcg cccagccaag acatggaaat   1560

gcccctcatt aaccagcaca aacaggccaa actcaaagag atcagcctgt ctgcggtgag   1620

gttcatggag gagctgggag aggaccggtt tgggaaagtc tacaaaggtc acctgttcgg   1680

ccctgccccg ggggagcaga cccaggctgt ggccatcaaa acgctgaagg acaaagcgga   1740

ggggcccctg cgggaggagt tccggcatga ggctatgctg cgagcacggc tgcaacaccc   1800

caacgtcgtc tgcctgctgg gcgtggtgac caaggaccag cccctgagca tgatcttcag   1860

ctactgttcg cacggcgacc tccacgaatt cctggtcatg cgctcgccgc actcggacgt   1920

gggcagcacc gatgatgacc gcacggtgaa gtccgccctg gagccccccg acttcgtgca   1980

ccttgtggca cagatcgcgg cggggatgga gtacctatcc agccaccacg tggttcacaa   2040

ggacctggcc acccgcaatg tgctagtgta cgacaagctg aacgtgaaga tctcagactt   2100

gggcctcttc cgagaggtgt atgccgccga ttactacaag ctgctgggga actcgctgct   2160

gcctatccgc tggatggccc cagaggccat catgtacggc aagttctcca tcgactcaga   2220

catctggtcc tacggtgtgg tcctgtggga ggtcttcagc tacggcctgc agccctactg   2280

cgggtactcc aaccaggatg tggtggagat gatccggaac cggcaggtgc tgccttgccc   2340

cgatgactgt cccgcctggg tgtatgccct catgatcgag tgctggaacg agttccccag   2400

ccggcggccc cgcttcaagg acatccacag ccggctccga gcctggggca acctttccaa   2460

ctacaacagc tcggcgcaga cctcgggggc cagcaacacc acgcagacca gctccctgag   2520

caccagccca gtgagcaatg tgagcaacgc ccgctacgtg gggcccaagc agaaggcccc   2580

gcccttccca cagccccagt tcatccccat gaagggccag atcagaccca tggtgccccc   2640

gccgcagctc tacgtccccg tcaacggcta ccagccggtg ccggcctatg gggcctacct   2700

gcccaacttc tacccggtgc agatcccaat gcagatggcc ccgcagcagg tgcctcctca   2760

gatggtcccc aagcccagct cacaccacag tggcagtggc tccaccagca caggctacgt   2820

caccacggcc ccctccaaca catccatggc agacagggca gccctgctct cagagggcgc   2880

tgatgacaca cagaacgccc cagaagatgg ggcccagagc accgtgcagg aagcagagga   2940

ggaggaggaa ggctctgtcc cagagactga gctgctgggg gactgtgaca ctctgcaggt   3000

ggacgaggcc caagtccagc tggaagcttg agtggcacca gggcccgggg ttcggggata   3060

gaagccccgc cgagacccca cagggacctc agtcaccttt gagaagacac catactcagc   3120

aatcacaaga gcccgccggc cagtgggctt gtttgcagac tgggtgaggt ggagccctgc   3180

tcctctctgt cctctgacac agagagctgc cctgcctagg agcacccaag ccaggcaggg   3240

ggtctggcag cacggcgtcc tggggagcag gacacatggt catccccagg gctgtataca   3300

ttgattctgg tggtagactg gtagtgagca gcaaatgcct ttcaagaaaa taggtggcag   3360

cttcactcca tgtcatatat ggagtgaata tttcaaaacg ttgggaataa gggcctgcaa   3420

aaggcagcga ggaggcacct cgggtcttga ggttcctgac aaccgatctg gtctgttggt   3480

ttgaggatga aggggctcca tttctgctgc ctccctgctg agaatattct ccctttagca   3540

gccaaagatt cgctggaacg gaggctgccc tctgctgcct gttggggtcg gaagacaagg   3600

ggcttctgaa atgggagttc ctgagataca acaaaatgtg tgccttcaaa gaaactgaca   3660

gctttgtatt tggtgaaatg gttttaatta tactccatgt gtattttgcc cacttttttt   3720

gggaattcaa gggaaagtgt ttcttgggtt tggaatgttc agaggaagca gtattgtaca   3780

gaacacggta ttgttatttt tgttaagaat catgtacaga gcttaaatgt aatttatatg   3840

tttttaatat gccattttca ttgaagtatt ttggtcttaa gatgacttta gtaatttaac   3900

tgtttatgtt acccacgttg ggatccagtt ggtcttggtt tgcttctctc tgtaccacgt   3960

gcacatgagg tccattcatt ttacagcccc tgttacacac agacccacag gcagccgtct   4020

gtgccccgca cacattgttg gtcctatttg taaatcccac acccggtgta tccaataaag   4080

tgaaacaaag catgtgaaa                                                4099


<210>  932
<211>  2117
<212>  DNA
<213>  Homo sapiens

<400>  932
acttcgggga aggggaggga ggagggggac gagggctctg gcgggtttgg aggggctgaa     60

catcgcgggg tgttctggtg tcccccgccc cgcctctcca aaaagctaca ccgacgcgga    120

ccgcggcggc gtcctccctc gccctcgctt cacctcgcgg gctccgaatg cggggagctc    180

ggatgtccgg tttcctgtga ggcttttacc tgacacccgc cgcctttccc cggcactggc    240

tgggagggcg ccctgcaaag ttgggaacgc ggagccccgg acccgctccc gccgcctccg    300

gctcgcccag ggggggtcgc cgggaggagc ccgggggaga gggaccagga ggggcccgcg    360

gcctcgcagg ggcgcccgcg cccccacccc tgcccccgcc agcggaccgg tcccccaccc    420

ccggtccttc caccatgcac ttgctgggct tcttctctgt ggcgtgttct ctgctcgccg    480

ctgcgctgct cccgggtcct cgcgaggcgc ccgccgccgc cgccgccttc gagtccggac    540

tcgacctctc ggacgcggag cccgacgcgg gcgaggccac ggcttatgca agcaaagatc    600

tggaggagca gttacggtct gtgtccagtg tagatgaact catgactgta ctctacccag    660

aatattggaa aatgtacaag tgtcagctaa ggaaaggagg ctggcaacat aacagagaac    720

aggccaacct caactcaagg acagaagaga ctataaaatt tgctgcagca cattataata    780

cagagatctt gaaaagtatt gataatgagt ggagaaagac tcaatgcatg ccacgggagg    840

tgtgtataga tgtggggaag gagtttggag tcgcgacaaa caccttcttt aaacctccat    900

gtgtgtccgt ctacagatgt gggggttgct gcaatagtga ggggctgcag tgcatgaaca    960

ccagcacgag ctacctcagc aagacgttat ttgaaattac agtgcctctc tctcaaggcc   1020

ccaaaccagt aacaatcagt tttgccaatc acacttcctg ccgatgcatg tctaaactgg   1080

atgtttacag acaagttcat tccattatta gacgttccct gccagcaaca ctaccacagt   1140

gtcaggcagc gaacaagacc tgccccacca attacatgtg gaataatcac atctgcagat   1200

gcctggctca ggaagatttt atgttttcct cggatgctgg agatgactca acagatggat   1260

tccatgacat ctgtggacca aacaaggagc tggatgaaga gacctgtcag tgtgtctgca   1320

gagcggggct tcggcctgcc agctgtggac cccacaaaga actagacaga aactcatgcc   1380

agtgtgtctg taaaaacaaa ctcttcccca gccaatgtgg ggccaaccga gaatttgatg   1440

aaaacacatg ccagtgtgta tgtaaaagaa cctgccccag aaatcaaccc ctaaatcctg   1500

gaaaatgtgc ctgtgaatgt acagaaagtc cacagaaatg cttgttaaaa ggaaagaagt   1560

tccaccacca aacatgcagc tgttacagac ggccatgtac gaaccgccag aaggcttgtg   1620

agccaggatt ttcatatagt gaagaagtgt gtcgttgtgt cccttcatat tggaaaagac   1680

cacaaatgag ctaagattgt actgttttcc agttcatcga ttttctatta tggaaaactg   1740

tgttgccaca gtagaactgt ctgtgaacag agagaccctt gtgggtccat gctaacaaag   1800

acaaaagtct gtctttcctg aaccatgtgg ataactttac agaaatggac tggagctcat   1860

ctgcaaaagg cctcttgtaa agactggttt tctgccaatg accaaacagc caagattttc   1920

ctcttgtgat ttctttaaaa gaatgactat ataatttatt tccactaaaa atattgtttc   1980

tgcattcatt tttatagcaa caacaattgg taaaactcac tgtgatcaat atttttatat   2040

catgcaaaat atgtttaaaa taaaatgaaa attgtattat aaaaaaaaaa aaaaaaaaaa   2100

aaaaaaaaaa aaaaaaa                                                  2117


<210>  933
<211>  2543
<212>  DNA
<213>  Homo sapiens

<400>  933
ggtgcggacg catgcgtagt gggcttctcg ggcggtgggg tgggcgcgga atttggagac     60

ccacttcggg aaagtcagga tggtggtgcc ttcgctgaag cttcaggacc tcatcgaaga    120

gattcgcggg gccaagactc aggcccagga gcgggagtga cctgagccag gggattcagc    180

cagtacaagg cctggccttg tgcactttga gcaccatggg ctctgctgag atgtgccgag    240

acctggcccc agaggtggag aaactgctcc tgcagcccag tccctacgtg cgcaagaagg    300

ctattctgac tgcagtgcac atgatccgga aggtccctga actctccagt gtcttcctcc    360

caccctgtgc ccaactgctt catgagcgtc accatggtaa ggctgtgggg ccccccatcc    420

tttgcttcag gtctatggac agaagaattg aaaatcggat gggaacccca gctcacagga    480

gaagggtagt gcacacacac aggcacacac gcaatagact ctcttgcccc tggcccccac    540

cattcacttc cccgacgctg accccaggca tcctgctggg caccatcacg ctgatcacgg    600

agctctgcga acgaagccct gcagccctca ggcacttccg aaaggtggta ccccagctgg    660

tacacatcct ccggactctg gtgacaatgg gatactccac agaacacagc atatctggag    720

tcagcgaccc cttcctgcag gtccagatac ttcgtctgct tcggatcctg ggccggaacc    780

acgaggagag cagtgagacc atgaatgact tgctggccca ggtggccact aacacggaca    840

ccagccgaaa tgccggaaat gcggtcctgt ttgagacagt actcaccatc atggatatcc    900

gctctgcagc tggcctacgg gttctagctg tcaacattct tggtcgcttc ctactcaaca    960

gtgacaggaa cattaggtat gtagccctga catcactgct tcgactggtg cagtctgatc   1020

acagtgctgt gcagcggcat cggcccactg tggtggaatg tctacgggaa actgatgcct   1080

ccctcagccg gagagccctg gaactaagcc tggctctggt aaatagctcc aatgtgcgag   1140

ccatgatgca agagctgcag gcctttctgg agtcctgccc tcctgaccta cgggctgact   1200

gtgcctcagg catcctgctg gctgcagaga ggtttgctcc aaccaaacgc tggcacatag   1260

acaccatcct gcatgtgctg acaacggcgg gcacccatgt gcgggatgat gcagtggcca   1320

acctgaccca gctgattggg ggggcccagg agctacatgc ctactctgtg cgccgcctct   1380

acaatgccct ggcagaagac atttcccagc aaccactggt gcaggtggca gcctggtgca   1440

ttggggagta tggggacctc ctgctggcag ggaactgcga ggagattgag ccccttcagg   1500

tggacgaaga ggaagtgctg gcattgctgg aaaaggtgct gcagtcccac atgtccctgc   1560

cagccactcg aggatatgcc ctcacagccc tcatgaagct cagcactcgc ctctgtgggg   1620

acaacaaccg catccgccag gtggtgtcca tctacgggag ctgcttggac gtggagctgc   1680

agcagcgggc tgtggagtat gacacactct tccggaaata cgaccacatg agggctgcca   1740

tcctggaaaa aatgcctctt gtggagcgag atggccctca ggctgatgag gaagcaaagg   1800

aaagcaaaga agcagcccag ctttcagaag cagccccagt gcccacagag ccccaggcct   1860

cacagctcct ggatctgcta gatctcctgg atggggcttc tggggatgtc cagcatcctc   1920

cccatctgga cccctcccca ggaggtgccc tggtacacct gcttgacctt ccctgtgtac   1980

ctccaccccc agctcccatc ccagatctca aagtgtttga gcgtgaggga gtacagctga   2040

atctgtcttt cattcgaccc cctgaaaacc ctgctttgct gttaatcacc atcactgcca   2100

ccaacttctc agagggtgat gtcacccatt tcatctgcca ggctgctgtg cccaagagtc   2160

tccagctgca gctgcaggcc cccagtggga acacagttcc agctcggggt ggccttccta   2220

tcacccagct cttcagaatc ctcaatccta acaaggcccc cctgcggcta aagctgcgcc   2280

tcacctacga ccactttcac cagtcggtgc aggagatctt tgaggtgaac aacttgcctg   2340

tggaatcgtg gcagtaactg tctccactca cagcctgaaa ttctcctgtg tcccaaaccc   2400

cagggggccc cagcagcttc gaacctacac ctgagggcta ccagcaggtg gcgctctggc   2460

tttgcactgc aaaaactggg gaccagcccc cttctcccac aaataaagcc caataaagcc   2520

tgagaagtga ggaaagccat att                                           2543


<210>  934
<211>  10151
<212>  DNA
<213>  Homo sapiens

<400>  934
gcagcgccgc ctgcccaggc ccggaccggg ctttgtccgc cccggagccc ctgcccgcgc     60

cgcggagacc ccggagcccg cgcgctccga ggccaccccg ggccgggatt tccggtgggg    120

cccgcggagc cgcgcagagg gaggaggccc cagacccagg cgccccgcca gcccagctgc    180

acgtaagcgg acgctgcagg agctgaagat ggcgagctcc gtggcgccct acgagcagct    240

ggtgaggcag gtggaggcct tgaaggctga gaacagccac ctgaggcagg agctaaggga    300

caactccagc cacctgtcca agctggagac agagacgtcg ggcatgaagg aggtcctgaa    360

gcacctacag ggaaaactgg agcaggaggc ccgagtgctg gtgtcctcgg ggcagacgga    420

ggtgctggag cagctgaagg ccctacagat ggacatcacc agcctgtaca acctcaagtt    480

ccagccgccc accctgggcc cggagcctgc cgcccggacc cccgagggca gcccagtaca    540

cggctccggg ccctccaagg acagctttgg ggagctgagc cgggccacca tccggctgct    600

ggaggaactg gaccgggaac ggtgtttcct gctgaatgag attgagaagg aggagaagga    660

gaagctctgg tactactctc agctgcaggg cctgtccaag cgcctggacg agctgccgca    720

cgtggagacg cagttctcga tgcagatgga cctgatccgg cagcagcttg agttcgaggc    780

ccagcacatc cgctcgctga tggaggagcg cttcggcacc tcggacgaga tggtgcagcg    840

ggcacagatc cgcgcctcgc gcctggagca gattgacaag gagctgctgg aggcgcagga    900

ccgagtgcag cagacggagc cccaggcctt gctggcggtg aagtcggtgc cggtggacga    960

ggaccccgag acagaggtcc ccacacaccc tgaggatggc acccctcagc cgggcaacag   1020

caaggtggag gtggtcttct ggctgttgtc catgttggcg acgcgcgacc aggaggatac   1080

agcgcgcacg ctgctggcca tgtccagctc gcccgagagc tgcgtggcca tgcgccgctc   1140

gggctgtctg cctctgctgc tgcaaatcct ccacggcacc gaggccgcgg ccgggggtcg   1200

cgccggggcc ccaggggcac cgggcgccaa ggacgcacgc atgcgcgcca acgcggcgct   1260

gcacaacatc gtcttctcgc agccggacca gggcctggcg cgcaaggaga tgcgcgtcct   1320

gcacgtgctg gagcagatcc gggcctactg cgagacctgc tgggactggc tgcaggcccg   1380

agacggcggg cccgagggag gtggcgccgg cagcgccccg atccccatcg agccgcagat   1440

ctgccaggcc acctgtgctg ttatgaagct gtcctttgat gaggagtacc gccgtgccat   1500

gaacgagcta ggtgggctgc aggccgtggc agagctgctg caggttgact atgagatgca   1560

caagatgacc cgggacccgc tgaacctggc gctgcgccgc tacgcgggca tgaccctcac   1620

caacctcacc tttggggacg ttgccaacaa ggccaccctg tgtgcgcgcc gcggctgcat   1680

ggaggccatc gtggcccagc tggcctccga cagtgaggag ctccaccagg tggtgtccag   1740

catccttcgg aacttgtcct ggagggccga catcaacagc aagaaggtgc tgagggaggc   1800

gggcagcgtg actgccctgg tgcagtgtgt cctgcgggcc accaaggagt ccaccctgaa   1860

gagcgtgctg agcgccctgt ggaatctgtc tgcacacagc acagagaaca aggcggccat   1920

ctgccaggtg gatggcgccc tgggcttcct ggtgagcacc ctgacctaca agtgtcagag   1980

caactcgctg gccatcatcg agagcggcgg cggcatcctc cgcaatgtgt ccagcctcgt   2040

cgccacccgt gaggactaca ggcaggtgct ccgggatcac aactgtctgc agacgctgct   2100

gcagcatctg acttcgcaca gcctgaccat cgtgagcaac gcgtgcggca cgctctggaa   2160

cctgtcggcc cgcagcgccc gtgaccagga gctgctgtgg gacctgggcg ccgtgggcat   2220

gctgcgtaat ctggtgcact ccaagcacaa gatgatcgcc atgggcagcg ccgccgccct   2280

gcgcaacctg ctggcccatc ggcccgccaa gcaccaggcg gccgccaccg ccgtgtcccc   2340

aggcagctgc gtgcccagcc tgtacgtgcg caagcagcgg gcgctggagg ccgagctgga   2400

cgcacggcac ctcgcgcagg cgctggagca cctggagaag cagggcccgc cggcagccga   2460

ggccgccact aagaagccgc tgccgcccct gcgacacctg gacggcctgg cccaagacta   2520

tgcttccgat tcgggctgct ttgacgacga cgatgcaccg tcatccctgg ctgcggccgc   2580

ggccaccggg gagccagcca gccctgccgc gctgtccctc ttcctgggca gccccttcct   2640

gcaggggcag gcgctggctc gcaccccgcc cacccgccga ggcggcaagg aggcagagaa   2700

ggacaccagt ggggaggcag ccgtggcggc caaggccaag gccaagctgg cgcttgcagt   2760

ggcgcgcatc gaccagctgg tggaggacat ctccgccctg cacacctcgt ccgacgatag   2820

cttcagcctc agctctggag acccgggaca ggaggcgcca cgggagggcc gcgcccagtc   2880

ctgctcgcca tgccgcggcc cggagggcgg gcggcgagag gcaggaagcc gggcgcaccc   2940

gctgctgcgg ctcaaggcgg cccacgccag cctctccaac gacagcctca acagcggcag   3000

tgccagcgac gggtactgcc cacgcgaaca tatgctgccc tgcccgctgg ccgcactggc   3060

ttcgcgccgc gaggacccca ggtgtgggca gcctcggccc agccggcttg accttgacct   3120

gcccggctgc caggccgagc ccccggcccg cgaggccacc tccgccgacg cccgcgtgcg   3180

caccatcaag ctgtcgccta cctatcagca cgtgccactg cttgagggtg cctcaagggc   3240

gggtgcagag cccctcgcgg ggcctggaat ctctccaggg gcccggaagc aggcctggct   3300

gccggcagac cacctgagca aggttcccga gaagctggcg gctgccccgc tgtctgtggc   3360

cagcaaggca ctgcagaaac tggcggcgca agaggggcca ctctcgctgt cccgatgcag   3420

ctccctttcc tcgctgtcct cggccggccg cccaggcccc agcgagggtg gtgacctgga   3480

tgacagtgac tcctccctgg aggggctgga ggaggccggc cccagcgagg ctgagctgga   3540

cagcacgtgg cgggcgcccg gggccacctc gctgcccgta gccattccgg ctccccggcg   3600

taaccgaggc cggggcctgg gggtggaaga cgccacgccg tccagctcgt cggagaacta   3660

cgtgcaggag acaccgcttg tgctgagccg ctgcagctct gtgagctcgc tgggcagctt   3720

cgagagcccg tccatcgcca gctccatccc cagtgaacct tgcagcgggc agggcagcgg   3780

caccatcagc cctagcgagc tgcccgacag ccccggacag accatgcctc ccagccggag   3840

caagacgcca ccgctggcgc ccgcgccaca gggtcccccc gaggccaccc agttcagcct   3900

gcagtgggag agctacgtga agcgcttcct ggacatcgcc gactgccggg agcgctgccg   3960

gctgccatct gagctggacg caggcagcgt gcgctttacc gtggagaagc cagacgagaa   4020

cttctcgtgc gcctccagcc tcagcgcgct ggccttgcac gagcactacg tgcagcagga   4080

cgtggagctg cggctgctgc cctcggcctg ccccgagcgc ggcgggggcg ccgggggcgc   4140

cggcctccac tttgcagggc accggcggcg ggaggagggg ccggcgccca cgggttctcg   4200

ccctcgcggc gccgcggacc aggagctgga actgctgcgg gagtgcctgg gagccgccgt   4260

gcctgcccgg ctgcgcaagg tggcctccgc gctggtgcca ggtcgccgcg cactccccgt   4320

gcccgtctac atgttggtgc ccgccccggc cccggcccag gaggacgact cctgcactga   4380

ctccgcggag ggcacgccgg tcaacttctc tagcgccgcc tcgctcagcg acgagacgct   4440

gcagggaccc cccagggacc agcccggggg accagcgggc aggcaaagac ccaccggccg   4500

ccccacctct gccagacagg ccatggggca ccggcacaag gcgggaggcg ccggccgcag   4560

cgcggagcag tctcggggcg cgggcaagaa cagagcaggg ctggagctgc ccctgggccg   4620

gcccccgagc gcccccgcag acaaggacgg ctcaaagccc ggccggaccc gcggggacgg   4680

ggcgctccag tcgctgtgcc tcacgacgcc cactgaggag gccgtgtact gcttctacgg   4740

caacgactcg gacgaggagc ccccggcggc cgcgcccacg ccaacccacc ggcgcacatc   4800

ggccatccct cgcgctttta cgcgggagcg tccgcagggc cggaaggagg cccctgcccc   4860

gtccaaggct gcaccagctg ccccgccgcc cgcccggacc cagcccagcc tcattgctga   4920

cgagaccccg ccctgctact ccctgagctc ctccgccagc tccctcagcg agcccgagcc   4980

ctcggagccg ccggccgtcc atccacgagg ccgggagccc gcggtcacca aggacccggg   5040

cccaggaggc ggacgcgaca gctcgcccag cccgcgggcc gcggaggagc ttctgcagcg   5100

gtgcatcagc tcggccctgc ccaggcgccg gccccccgtg tctggcctgc ggcgccgcaa   5160

gccccgagcc acccggctgg atgagcggcc cgcagagggg tcccgggaac gcggcgagga   5220

ggcagcgggc tcggaccggg cctccgacct ggatagcgtg gagtggcgcg ccatccagga   5280

gggcgccaat tcaattgtca cgtggctgca ccaggcagca gctgccacgc gggaggcctc   5340

gtccgagtcc gactccatcc tgtccttcgt atccgggctg tcagtgggat ccaccctaca   5400

gccccccaag cacaggaagg gacgacaggc ggagggagaa atgggcagtg cccggcggcc   5460

agagaaaagg ggcgcagcct cagtcaagac cagcgggagc ccccgttccc ctgcaggccc   5520

cgagaagcca cgtggcacac agaagaccac gcccggggtg ccagctgtgc tccggggacg   5580

aacagtgatc tacgtcccca gcccggcacc ccgtgcccag cccaaaggga cccccggccc   5640

ccgcgccaca ccgcggaagg tggcgccccc ttgcctggca cagcccgcgg ctccagccaa   5700

agtcccgagc cccgggcagc agcggtcgcg gagcctacac cggcctgcca agacctcgga   5760

gctggcgacg ctgagccagc cccccagaag cgccacaccg cccgcccgcc tcgccaagac   5820

cccctcctcc agctcctccc agacctcgcc cgcctcccag cccctgccca gaaagcgccc   5880

cccggtcacc caggctgctg gggccctgcc cggccccgga gcctccccgg tgcccaaaac   5940

gccggcgcgc acccttctgg cgaagcagca caagacgcag agatcgcccg tgcggatccc   6000

gttcatgcag aggccggccc ggcgtgggcc gccaccgctg gctcgggcag tcccggagcc   6060

gggccccagg ggccgggcgg ggaccgaggc gggcccgggg gcgcgcgggg gccgcctggg   6120

cctggtgcgt gtggcctcag ccctctccag cggcagcgag tcctccgacc gctcgggctt   6180

ccggcgacag ctaaccttca tcaaggagtc gccgggcttg cggcgccgcc gctccgagct   6240

gtcctcggcc gagtccgcgg cctctgcccc ccagggcgcc tcgccccgcc gcggccggcc   6300

cgcgctgccc gccgtcttcc tctgctcctc gcgctgcgaa gagctccgag cggcaccccg   6360

gcagggcccg gccccggccc ggcagcggcc ccccgcggcc cgacccagcc ctggcgagcg   6420

ccctgcccgg cgcaccacct ccgagagccc gtcccgcctg cctgtgcgcg cgcccgccgc   6480

ccggccggag actgtcaagc gctacgcgtc gctgccgcac atcagcgtgg cccgcaggcc   6540

cgacggcgcc gtccccgcgg cccctgcctc agccgacgcc gcgcgccgca gcagcgacgg   6600

ggagccccgg ccgctcccca gggtggccgc gccgggcacg acctggcggc gcatccgaga   6660

tgaggacgtg ccccacatcc tgcgcagcac gcttcccgcc acggccctgc cactgcgggg   6720

ctccacgccc gaggacgccc cggccgggcc cccgccgcgc aagaccagcg acgccgtggt   6780

ccagaccgag gaggtcgccg cccccaagac caactccagc acgtccccga gcctggagac   6840

cagggagccc cccggggccc ccgccggcgg ccagctctcc ctcctcggca gcgacgtgga   6900

cggtcccagc ctcgccaagg ctcccatctc cgcacccttc gtgcacgagg gcctgggggt   6960

cgccgtgggg ggcttccccg ccagccggca cggctccccc agccgctcgg cccgagtacc   7020

ccccttcaac tatgtgccca gccccatggt ggtcgcagcc accaccgact cggccgcgga   7080

gaaagccccg gccactgcct ccgccaccct cctggaatag tggcctaggc cggccttctg   7140

gaacgttctc tcccggccct gcggcgcggt ctggctgccc catgggcctg cgctgtagac   7200

gtcccccata ggtcgcccca gggcctctgc ccacccgagc cccaccactc tcagaacccc   7260

cgcccagcgc acggcgacct cgcgcctcac cggaagacct tgcctctgtg ccgcggaggt   7320

ccaggaggaa acggggcggc cgctaggcct caagtcccga ccgtggagcg ctggcaaggg   7380

cgtcctggcc cagccctgag cgcgcggccc ttcccctgtc ggaagccgtt gcttgacccc   7440

gggcgaggga ggcggtagcc tccgggtccg ggtctgggtc tgggtccgct gcttcgcagg   7500

gacagcgctg gggaggtgac ggcgcccgcc gcaggtgggg cgaggctggg ggagggcggc   7560

gccgcggcgg gcctgccagc tgggggcctt tgcggcgcgc aggggcgaag cctgtaatca   7620

ctgcagccgc cggtaattcg ctaatgaggg ctttgcaggg attgttttca ttctcagccc   7680

cagctgtggg agtgcgggtg ggggtgtggc cgagccccgg caggaagccc cgcccagacg   7740

gtgttcaggg aacccggagc ccaagcgctc cggcggagcc caaaagggtg ggggtgggag   7800

gggcagaggc caacggatcc ccctgcctgt cgcacccctt ggcgggagac gggaaggcag   7860

cgggctgcgt acgatgggac cctggtgcag acgccgggcc ggctgacatt tggaccccat   7920

cccagaggag atgctggcta ccagctgggg cgaccccaag ggtcgctgga gtcagtatcg   7980

gcccggcgca gccgcggcgg gcgaggccaa tggaaaggag actgagggga gtcccggcag   8040

tgagcccgag gccctgggac ctggagcccg cgctggcctc tccccagcgg agcctgcacg   8100

ttacggagac catcacatgt gggcgtggtc agtgcccagg accgcaccgc tgctcatctt   8160

gtcccttttc aattcccttc tggttcatga tgcataaagc gctaggccct agaactccag   8220

aaacagcaca gctggggcgg ggacccagcc ttgccctcca cccgaggctc tgggacaagg   8280

cgggaggttc gggggccttc cggcaggtga acgcagggct ggagagtatt tggtgccaga   8340

tgaggtgaaa gcttatagaa gggcctgagg ggctcggctg cctcatcccc tggcggggga   8400

ggctgggagc tgggcctcct gcgtggggtg ggactcgcag gggccgggtc tccgtgactg   8460

gggcaacgcc tcgtcctgca gagggagccg acgacctctt ttctgcagaa aagctccagc   8520

aggcgctgcc ttcacccacg gatctgccca ggctgaaggc acacgctcaa tgccccacgt   8580

gccttctcca ggaggaacga agcagggttt gagggttggg tggatggagc tcagaaggaa   8640

accccagccc caccacggat gacaccatcc ctcccgtccc atccccagca tgggcaaggc   8700

cagcctttct ggcagaagga gctgtcctca actcagggcc gctgtgagca aagctgaccc   8760

cagcccccac ccccagttaa cactgctgct tctctgaatg catgtcacgc tgcaccccat   8820

gctccgggcc cacaccctgc aggacaagga gctccagaca ggacgtccat aagtcaccga   8880

ggtgtgccac ccagcaggtg ctggaggtgc ccaatgctcc ctcctaggac ctcgcagcca   8940

ggcaaggctg tcaggttgtt ttgggggaag agggggtcat ggatggctga gcagagagcg   9000

gggaaaatgc aggctgagtg gggcgacctc ctgcctgcca ggagccccct ttcaggacac   9060

agcgggggtc tcacacttgc tgtccccatc catggcccga gggggaacct ggtggtctct   9120

tctgagcttt tggacttggg gatgccaaac acgtgctcac cctcacactc gccccggccc   9180

gctgcgcccc taattgccaa agggtaggga aatggcgaag ccagccacca ggtcgctggt   9240

gacagggcca gggttatgca ggaaggtggt gcggcattgc cttccacata tgtaagtctc   9300

tgggcggcgc cctcccagct ccctgcctct gtttccccat gtgggccgtg gggaactccc   9360

agagctacct cttgggggag cgtggtggca gcgatgatgg ggagacgcct ggaagctcac   9420

agaacttggg tctggctggc tcctgcccgt gacgccttgc ccagcagcaa ggtgcgcaac   9480

atggctgcca gccccgcctc ccacccccac cccgagtcct gagctcactt tcgccttctc   9540

catcccctgc cgtgggggcc acagccacac ctcaccgccc agtccagctg tctccagaag   9600

gggacaggca gtccgcggtc tctggacaat caactcaagg tacgcccact gcaaggcctc   9660

cctcccaccg cggcccctgc ctggccacct ggcctctctg caccagggtg acaaggggtc   9720

ctcgtctgcc ccccaatgct ccagggccag tcctaaggag ctgagggtct gaggacgcag   9780

ggagggtgga ggtgtcctga ggctgatgga cagtgaccgc cactggcccc caacatgacc   9840

acacgtgggt gctgaactcg gggcgccgtg cccaccggca tggtcctccc gagctccgac   9900

agcattacct cacccggccc catctgttgc cccggtccag ccctgatggc gcgcgcctgg   9960

tctgtctgat tcccctagcc gccaccccac gtttctgtac cgggtctctg cagtgttaaa  10020

cggacgtgta aatagtggta aatagtgaaa gcctgtcctt ccctaaatgt aaagccatct  10080

gtccggcgta aggacgacac cgtcagctgt ccgactcgca cacatttaat aaactgagct  10140

cttgcattgc c                                                       10151


<210>  935
<211>  1884
<212>  DNA
<213>  Homo sapiens

<400>  935
cttccatctg cccagagagg agcatctgga tcaaggtgct ggccatgtcc cagctggtgg     60

aatgcgtccc caacttttcg gaggggaaga accaggaggt gatcgacgcc atctctggag    120

ccatcacaca gaccccgggc tgcgtgctgc tggatgtgga cgcaggccct tccaccaacc    180

gcaccgtgta caccttcgtg gggccgccgg agtgcgtggt ggagggggcc ctcaacgctg    240

cccgggtagc ttcccgactt atcgacatga gcaggcacca aggagagcac ccccgcatgg    300

gggccctaga cgtctgcccc ttcatccccg tgaggggcgt cagcgtggat gagtgtgtgc    360

tctgcgccca ggcctttggc cagaggctgg cagaggagct ggacgtgcca gtttacctgt    420

acggcgaggc agccaggatg gacagtcgcc ggaccctgcc ggccatccgg gccggggagt    480

acgaggccct ccctaagaag ctccagcagg ccgactgggc gcccgacttt ggtcccagct    540

cctttgtccc cagttggggg gccacggcca cgggggcgag gaagttcctc attgctttta    600

acatcaacct gctcggcaca aaggagcaag cccaccgcat cgcgctcaac ctgcgggagc    660

agggccgcgg gaaggaccag ccaggacgtc tgaagaaagt tcagggcatt ggctggtacc    720

tggatgagaa gaacctggct caggtgtcca ccaatcttct ggactttgag gtcacggcac    780

tgcacacggt ctacgaggag acctgccgag aagcacagga gctgagcctc ccagtggtgg    840

gctcacagct ggtgggcctg gtgcccctga aggctctgct ggatgcggcc gccttctact    900

gcgagaagga gaacctcttc atcctggagg aggagcagcg gatcaggctg gtggtgagcc    960

ggctgggcct ggactccctg tgccccttca gccctaagga gcggatcatc gagtacctgg   1020

tccctgagcg cgggcctgag cgaggcctgg gcagcaagtc cctgcgcgcc ttcgtggggg   1080

aggtgggtgc ccgctctgcg gcccccgggg gcggctcggt ggcggcggcc gctgcggcca   1140

tgggtgcggc gctgggctcc atggtgggcc tcatgaccta cgggcggcgc caattccagt   1200

ccctggacac gacgatgcgg cgcctgatcc cgcccttccg cgaggcttcg gccaagctaa   1260

ccacgctggt ggatgccgac gccgaggcct tcaccgccta cctggaagca atgaggctcc   1320

ccaagaacac acctgaggaa aaggacaggc gcacggcggc cctacaggag ggtctgaggc   1380

gggcagtctc tgtgccgctg acgctggcgg agacggtggc ctcgctgtgg ccggccctgc   1440

aggaactggc ccggtgtggg aacctggcct gccggtcaga cctccaggtg gcggccaaag   1500

ccctggagat gggcgtgttt ggcgcatatt tcaacgtgct catcaacctg agggacatca   1560

cagacgaggc atttaaggac cagatccacc atcgtgtttc cagcctcctg caggaagcca   1620

agacccaggc tgcactggtg ctggactgct tggagacccg gcaggagtga cggtgcggga   1680

ggcctctccg ggctctgtgg cccctccctc gcccatcccc agagggcaga gctgtgacct   1740

cggtggggac acagcttgtt cgtgtggggc ccggagggta ggtgggcagg cagcggggca   1800

tcgcctggga atggaggcgc tggcagggac agaaggcccc tagtcccatg tgacctccag   1860

taaagttttg gcaccaaaaa aaaa                                          1884


<210>  936
<211>  986
<212>  DNA
<213>  Homo sapiens

<400>  936
ggcgaatctg ctgctaccaa tgtaaaggtc aggccgaggc cggcgcggag aatctgctgt     60

cgcctgcagc tgctcgcctg tctccgtcgg aagggagccc aagctttgca gagaacatga    120

acgattggat gcccatcgcc aaggagtatg atccactcaa agcgggcagc attgatggca    180

ccgatgaaga cccacacgac cgcgcggtct ggagggcaat gctggcacga tatgtcccca    240

acaaaggtgt cataggagat cccctcctca ccctgtttgt ggccagacta aacttgcaga    300

ccaaggagga caaattaaag gaagtctttt cccgctatgg tgacatccgg cggcttcggc    360

tggtcaggga cttggtcaca ggtttttcaa agggctacgc cttcatcgaa tacaaggagg    420

agcgtgccgt gatcaaagct taccgagatg ctgatggcct ggttattgac cagcatgaga    480

tatttgtgga ctacgagctg gaaaggactc tcaaagggtg gatccctcgg cgacttggag    540

gcggtcttgg gggaaaaaag gagtctgggc aactgagatt tgggggacgg gaccggcctt    600

ttcgaaaacc tattaacttg ccagttgtta aaaacgacct ctatagagag ggaaaacggg    660

aaaggcggga gcgatctcga tcccgagaaa gacactggga ctcgaggaca agggatcgag    720

accatgacag gggccgggag aagagatggc aagaaagaga gccgaccagg gtgtggcccg    780

acaatgactg ggagagagag agggacttca gagatgacag gatcaagggg agggagaaga    840

aggaaagagg caagtagagg cccaacagca gaaccccaaa gtgaagttac agtggaaatg    900

agtggagggg gattgtcttt caacgcagcg tgagtctaat ggttgaataa aacttactga    960

tgatcatggg aaaaaaaaaa aaaaaa                                         986


<210>  937
<211>  1031
<212>  DNA
<213>  Homo sapiens

<400>  937
cgacagccgg aagtcccgcc tgccgtgtag tcgccgccgt cgctgccgct gccgctgccg     60

ccgtcgttgt tgttgtgctc ggtgcgctga gctccgcggc tccgcgagcc ggttccgtcc    120

ccttcccgcc gccgccatga agtggatgtt caaggaggac cactcgctgg aacacagatg    180

cgtggagtcc gcgaagattc gagcgaaata tcccgacagg gttccggtga ttgtggaaaa    240

ggtctcaggc tctcagattg ttgacattga caaacggaag tacttggttc catctgatat    300

cactgtggct cagttcatgt ggatcatcag gaaaaggatc cagcttcctt ctgaaaaggc    360

gatcttcctg tttgtggata agacagtccc acagtccagc ctaactatgg gacagcttta    420

cgagaaggaa aaagatgaag atggattctt atatgtggcc tacagcggag agaacacttt    480

tggcttctga gggccattgc tgggctaggt gcaccgtaac tgcttgtgta tcttgtaaat    540

agccagccat tttcagttat tataccagaa cctcttcaca tagacctatt agtgcatttg    600

taactggatt tatttcttaa tatattggaa ggttttgttt ccttagacta gtaaattatc    660

atacagagtt ttattttgag tttttctttt tgtgcattgt cctcatgcct gtattctcca    720

ggaaacttgt ccttctggaa atcatattga atgatatttc tatatcgaag tgaggtaggt    780

gcggtattaa agtgaaaggg aaggtgatgc atttattctg ggttatgctt gaagtgttag    840

atggctaagt attaaaatta tccaaattaa atccttagca gtcagaacac ttgcttcact    900

agaatatgcc aactgccaat catgttggac tgagctaatt tgttcctctt tctgaaacta    960

ttaaggtaaa taattaacaa taaaaattct cttataaagg caaaaaaaaa aaaaaaaaaa   1020

aaaaaaaaaa a                                                        1031


<210>  938
<211>  2422
<212>  DNA
<213>  Homo sapiens

<400>  938
aagaggactg tcagaaggac gtagaaggca cggttttact gtgaggagca aagattcttt     60

acctacgcat tttacaagaa atgtgcagaa agccattgat aaatatacct gcggaagcca    120

tacacccacg ggagcccaca cctcttggtc tgggtcggcc acacagagct ctaccaccgg    180

ctcatccacg gagaggggct ccgtttattc ctggagagat gacgaatttg acgaagccag    240

ttcacagtca gtgcagcggt tactctggga ggtggaggaa atgttatttg aagggaaagt    300

gaaccctcag acccagagtc tgctggccga atgcggggag tggacaagaa gatccctcca    360

tttgagagta ttaggaagac agctgatcct gcccactgac aaaggcgtcc agcatttcca    420

gggcagcact cctgcctccg cagtccacag acccccgctc agtgcctgcg gacacagcag    480

caacatcaga gagttgtgca tttctggctc tcaaatagtc ccagcagcac tctcagcctc    540

tgccctgcca ggccctgatg acacaggggt tgctgaccta acggcacgtt catccctgga    600

agaagaggtt taccatgtgg atggaaagat tgaggagtat ttcgcttttg acagaaaaga    660

ggatgatgat gaatgtcttg aacaaaaacc agctcagccc ggtaggaaat ggcgcaaact    720

cggacttcct cctgtttccc cgcgtgactg tgtcaaagat gccgtggcag cagaagtgtt    780

tgatcacgtc tggacaaata tggtagaact tttggaagag ctgattagaa aacactggga    840

aactacactc acagaaggga aaaaacagag agaaacattg aaagtggctg gaaacagatt    900

tccgcacgtc ctcgttccac acgctcacgc cgatggagcc agtggccccc cgtccggaca    960

cgccgaggct cacggcatct ccctggcttc tcgtctgaac ccgccccaga ttcatcactt   1020

ctccagcagt ttttatagtg acatgaatgg tgtcatgaca attcaagcaa aaccgcttca   1080

gcggagacct gcctattttg ctgacagaac gcagaatgag aaggaggaca aagcatcggg   1140

tggaggggca ggtgctctct cctccgcacc gcacagactg ggacgggcct cagacactca   1200

tggattatca ccttctgcaa agaaaacacc agtgccctgg aggctgcctt ctcttgcttc   1260

agattcacag agactaaaaa ctcccaacat ctatagtgac gaagttcttc ggggaacaaa   1320

actgccgact ggcgtggacc acatggcttc cccactggtt caaacgtcac ggagcaggtt   1380

ccccccgcta gtcacggaga ccagggggca gaatacagca gttcctggat gccgccttgt   1440

ttcttacaga ggaaggcatc tacaaaaccg tgtgttgagt gccatgcctg acggtacaga   1500

acgatcgcgt cttcgagaaa gaacagccac cctggaacgg ttgtcaaggc ccagcacaac   1560

ccacacgttc cggcagtcgg atacgcctcg aaaaagttca ttgacacaaa tggaatttgc   1620

tgctcacaca tggacaggtc aaagtatttt gacaggttca caatatgtgc ctaaatcttt   1680

tcagaggaca actttgactt tcaagaggag attccaagtg acatcttgaa accacctcac   1740

cagaaccatt ggagcacctg tggcctcggc acactgctta tcacttgaaa aatggaggaa   1800

caagtgttat atttatctgt gtgtctgaca gtgtgagatg ttagaccgag agaaaagcaa   1860

acaaataaat cacttaatct tgaacacttt gcactgtaaa gagagtgaaa gtcaaaccca   1920

ccaagctgcc ttgctgaaag catctccaag gttctgtagg ctttgttcag aagcccctga   1980

tgtgtgtttg cagtccgtca ttttatcaat gatacgcaaa cataattagc atgtgtatgt   2040

actcacacac taattacatg taagaatata ttatctagga atatgtcatt tgtaactttg   2100

tactctgacg tattttctag tctcacccta ttagtaattc tgtcaaaatc ctagacgcta   2160

gtagatatta gtatttgaga caatatgtca gagtctgaat aagactcagc ttgttctagt   2220

catgctgagt ttctcatata ttttttaaaa gtgcttccgc catgaacctc tttgagaaat   2280

gtcagtggca aaatctccca agctaatttt ctttttctat gttccatctt caaattcaga   2340

cagttcacgt gaagtacccc acatttattg atcttagggt tgaatataaa cgcaattaaa   2400

agctaaaaaa aaaaaaaaaa aa                                            2422


<210>  939
<211>  3715
<212>  DNA
<213>  Homo sapiens

<400>  939
gccgccgccg ccgccgccgc cgcgccgcgg cttgagggcg ggaggctggg ggagggtagc     60

ggagccggcg ccgccgccat gttgggtctg aagcggctgc tgtaggcgcc gacggagcga    120

gcgggcgtgc ggagcgggcg acagtggcgt gggatctgcc tctctgcgag cagctgggag    180

cggcggcggc ggcgccatga gcgggggcac cccttacatc ggcagcaaga tcagcctcat    240

ctccaaggcg gagatccgct acgagggcat cctctacacc atcgacaccg aaaactccac    300

cgtagccctt gccaaagttc gatcctttgg tacagaagac agaccgacag atcgtccaat    360

accacctcga gatgaagtct ttgaatacat tatattccgt gggagtgaca ttaaagacct    420

tactgtttgt gagccaccaa aaccacagtg ttctttgcct caagacccag ctattgttca    480

gtcctcacta ggctcatcga cttcttcatt ccagtccatg ggttcttatg gacctttcgg    540

caggatgccc acatacagtc agttcagtcc gagttcctta gttgggcagc agtttggtgc    600

tgttggtgtt gctggaagct ctttgacatc ctttggaaca gaaacatcaa acagtggtac    660

cttaccccaa agtagtgcgg ttggttctgc ctttacacag gatacaagat ctctaaaaac    720

acagttatct caaggtcgct caagccctca gttagaccct ttgagaaaaa gcccaaccat    780

ggaacaagca gtgcagaccg cctcagccca cttacctgct ccagcagctg ttgggagaag    840

gagtcctgta tcaaccaggc ctttgccatc tgccagccaa aaggcaggag agaatcagga    900

gcacaggcga gctgaagtac acaaagtttc aaggccagaa aatgagcaac tcagaaatga    960

taacaagaga caagtagctc caggtgctcc ttcagctcca aggagagggc gtgggggtca   1020

tcggggtggc aggggaagat ttggtattcg gcgagatggg ccaatgaaat ttgagaaaga   1080

ctttgacttt gaaagtgcaa atgcacaatt caacaaggaa gagattgaca gagagtttca   1140

taataaactt aaattaaaag aagataaact tgagaaacag gagaagcctg taaatggtga   1200

agataaagga gactcaggag ttgataccca aaacagtgaa ggaaatgccg atgaagaaga   1260

tccacttgga cctaattgct attatgacaa aactaaatcc ttctttgata atatttcttg   1320

tgatgacaat agagaacgga gaccaacctg ggctgaagaa agaagattaa atgctgaaac   1380

atttggaatc ccacttcgtc caaaccgtgg ccgtggggga tacagaggca gaggaggtct   1440

tggtttccgt ggtggcagag ggcgtggtgg tggcagaggt ggtaccttca ctgcccctcg   1500

aggatttcgc ggtggattca gaggaggtcg tgggggccgg gagtttgcgg attttgaata   1560

taggaaagac aacaaagttg ctgcatagtc tacaaacaag tctctgaaaa taggtgaatt   1620

tctagctctt catggtcctg aacattgatt tcagtctttg caaagaatga agaagtgaat   1680

tcgctgtaca tttgtcacca gcactgggtt tttgtttttt gtttgttttt ccgcttaatt   1740

tcaaagataa aatgcagtta cttttggggg tggaaggctc atcttaaaac atgagcatta   1800

aatatatttg gaatagcaga aggttaagta atttcttatg tatagttaaa ctaaagcagt   1860

acttcagtgg gacttaacaa gtattttttc atcactgaaa ggtttttttt ttttatcact   1920

aaattgtatt tggcaattgc aagttgcctg cagatagggc cgtgatactg tgttttgagc   1980

cacagaaggt tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgta tgtgtgtgtc   2040

tttttcctcc tttcttttgg ggaatcctgt aatatgaggt agcttatttc gtcaattaat   2100

tagggtgctg gatggtagag aattttgtca gtcaactatg tacacacagt aaatactgtt   2160

tcttaggcaa aggtaacttt tttatatagt tgtaaaattc cattatattc cattgccaaa   2220

gaaacattaa gaactttgta tagctgtata aaaagcaact aattttttaa agaataaaca   2280

ttttaaagtc agcaaacata ctgtgtcctt gcagaagttg atgtgctgag cagcagcctt   2340

atgggtgggt ctttttttct tagttttcca ggcttaacat ttttgatttt gttttttaat   2400

gtttggaaca taaatgaaga tttgatacat tatttcatta tctaaaaagg attaattatt   2460

catgctcatt gtaagaactt cattttgtag caaatggcat atcacaggat ctgtccagat   2520

aatcgatatt ttcagtatac aaatgtaaat aatcacagat gagaatgtac ttagctgtat   2580

tttcaaataa gtaatcttcc ccccttttgt aggactttaa aactaggcat caatgaacct   2640

gtttttccta ttatgcctgg aatttagtca tgataccttg actcattcca tcatatttca   2700

agaggattca gagtgctaga aattattttg gtagcctgta acacacggca acactggtcc   2760

ttgggcctat gatgacccac agatgactca gtatagagtt cattgctaat tataaattac   2820

tagtgaatct ttttgatatt ttaagctcta gtgggaaaaa tctggccact tttgtgtttt   2880

tatgaaggcc atggaataaa aggatccaaa gatttaaata tttttatcta atattttgat   2940

tgttttctta actttctcct taaaacattc agtagtgata aagatataga aactgcactg   3000

taggagaatt ggaatattta aggctggttg acatttttta ttttcatttt atatcttttg   3060

tatagctcta caaggcagtg ttttgtaatt tggtttcatt atgaagatcc agtacttggc   3120

agccatagtt tagacaatat tgttcagtgc tgtttgcttg catgttaaca acaaaacctt   3180

ttagaggacc cacaaatcat gatattgaac acagttccga ggcattcaga gcatcagagc   3240

aagtaccatg gcaatacatg tgtagactgt tggagatgtc ccgggccaat ttcaagaaag   3300

aaaactgtaa atactagttc tacttgctct gaaattatga gtttatgcgt tttcccagcc   3360

ctccgaatca ctgactgggg cgttttgtgc cccagcaata actggcagca tggcatacct   3420

gcagtacccc ttacaatatt aaagcaaagt ttttattcta aaacagaata aaactgttca   3480

ataaaaaatg ctcgtcaaag ttctttctct ttaaatagta acattctgtt tcagtaggaa   3540

cataatgaaa ggaatctttt aaatggaaga gcggaattat aatgtttgta ttccctgtaa   3600

taactataaa tcagttactt tatttctaag attgagttat tgttgcagat gtttagggaa   3660

agctaaaagc cccttccttc ccctcctgtg tgtaaataaa atacttctga gatca        3715


<210>  940
<211>  1119
<212>  DNA
<213>  Homo sapiens

<400>  940
gacgcatttc cggttccctt cgtttaggtc ggctggaaat tatgtcctcc gtcggttttc     60

cgcagttttt ccaccaagcg agatattttt gggagttatt ccctaaataa ctgcattata    120

tgctcctttc atgacgaaat tgctgccgtg gagaagactg gaggaaactc gaggaagagg    180

gagaagccga caagtgctcg acgggctagg aactgtcctg cttgggtgtt agcgtttccc    240

gccgggccag taaggctgag tgacccggcg tggctactag gagaaggacg tacggtcctg    300

ctagtagagg aatatgtcga gtttctctag ggcgccccag caatgggcca cttttgctag    360

aatatggtat ctcttagatg ggaaaatgca gccacctggc aaacttgctg ctatggcatc    420

tataagactt cagggattac ataaacctgt gtaccatgca ctgagtgact gtggggatca    480

tgttgttata atgaacacaa gacacattgc attttctgga aacaaatggg aacaaaaagt    540

atactcttcg catactggct acccaggtgg atttagacaa gtaacagctg ctcagcttca    600

cctgagggat ccagtggcaa ttgtaaaact agctatttat ggcatgctgc caaaaaacct    660

tcacagaaga acaatgatgg aaaggttgca tctttttcca gatgagtata ttccagaaga    720

tattcttaag aatttagtag aggagcttcc tcaaccacga aaaataccta aacgtctaga    780

tgagtacaca caagaagaaa tagacgcctt cccaagattg tggactccac ctgaagatta    840

tcggctataa gagaataaga attgcagaaa ataacagtga agtgattgaa actttcttct    900

gatgagtttc tctaacctac aggatggagt aaaacaactg ctacagttca gcacctgttt    960

tatgtgccga atcactgtgg ggaaaggtca ggaaggtata gtccttcaat aggaaattgt   1020

aattaaaata taattttata gaaccatttt tatgtaatct gatttgaatg ttatagttga   1080

taataataaa atcacttact tggttgacta aaaaaaaaa                          1119


<210>  941
<211>  4868
<212>  DNA
<213>  Homo sapiens

<400>  941
agttagcgcc tgctgggtgt ctgctcgggt ggtctgggaa ctacaattcc cggcgggctg     60

tgagatgcct tggctgtagt tagtaaggag ccggatgatt gcctcagcag gtgtgaagcg    120

tgtgctttag tttcgtggga ggcctggcat ccccgagagg gaggggaaag gtaaccactc    180

ctttgtggag gtcgccaggg tcattgtcgt ggatttgcac agtcggctgg gcggtgcaat    240

ggcggaaaga aaaggaacag ccaaagtgga ctttttgaag aagattgaga aagaaatcca    300

acagaaatgg gatactgaga gagtgtttga ggtcaatgca tctaatttag agaaacagac    360

cagcaagggc aagtattttg taaccttccc atatccatat atgaatggac gccttcattt    420

gggacacacg ttttctttat ccaaatgtga gtttgctgta gggtaccagc gattgaaagg    480

aaaatgttgt ctgtttccct ttggcctgca ctgtactgga atgcctatta aggcatgtgc    540

tgataagttg aaaagagaaa tagagctgta tggttgcccc cctgattttc cagatgaaga    600

agaggaagag gaagaaacca gtgttaaaac agaagatata ataattaagg ataaagctaa    660

aggaaaaaag agtaaagctg ctgctaaagc tggatcttct aaataccagt ggggcattat    720

gaaatccctt ggcctgtctg atgaagagat agtaaaattt tctgaagcag aacattggct    780

tgattatttc ccgccactgg ctattcagga tttaaaaaga atgggtttga aggtagactg    840

gcgtcgttcc ttcatcacca ctgatgttaa tccttactat gattcatttg tcagatggca    900

atttttaaca ttaagagaaa gaaacaaaat taaatttggg aagcggtata caatttactc    960

tccgaaagat ggacagcctt gcatggatca tgatagacaa actggagagg gtgttggacc   1020

tcaggaatat actttactca aattgaaggt gcttgagcca tacccatcta aattaagtgg   1080

cctgaaaggt aaaaatattt tcttggtggc tgctactctc agacctgaga ccatgtttgg   1140

gcagacaaat tgttgggttc gtcctgatat gaagtacatt ggatttgaga cggtgaatgg   1200

tgatatattc atctgtaccc aaaaagcagc caggaatatg tcataccagg gctttaccaa   1260

agacaatggc gtggtgcctg ttgttaagga attaatgggg gaggaaattc ttggtgcatc   1320

actttctgca cctttaacat catacaaggt gatctatgtt ctcccaatgc taactattaa   1380

ggaggataaa ggcactggtg tggttacaag tgttccttcc gactcccctg atgatattgc   1440

tgccctcaga gacttgaaga aaaagcaagc cttacgagca aaatatggaa ttagagatga   1500

catggtcttg ccatttgagc cggtgccagt cattgaaatc ccaggttttg gaaatctttc   1560

tgctgtaacc atttgtgatg agttgaaaat tcagagccag aatgaccggg aaaaacttgc   1620

agaagcaaag gagaagatat atctaaaagg attttatgag ggtatcatgt tggtggatgg   1680

atttaaagga cagaaggttc aagatgtaaa gaagactatt cagaaaaaga tgattgacgc   1740

tggagatgca cttatttaca tggaaccaga gaaacaagtg atgtccaggt cgtcagatga   1800

atgtgttgtg gctctgtgtg accagtggta cttggattat ggagaagaga attggaagaa   1860

acagacatct cagtgcttga agaacctgga aacattctgt gaggagacca ggaggaattt   1920

tgaagccacc ttaggttggc tacaagaaca tgcttgctca agaacttatg gtctaggcac   1980

tcacctgcct tgggatgagc agtggctgat tgaatcactt tctgactcca ctatttacat   2040

ggcattttac acagttgcac acctattgca ggggggtaac ttgcatggac aggcagagtc   2100

tccgctgggc attagaccgc aacagatgac caaggaagtt tgggattatg ttttcttcaa   2160

ggaggctcca tttcctaaga ctcagattgc aaaggaaaaa ttagatcagt taaagcagga   2220

gtttgaattc tggtatcctg ttgatcttcg cgtctctggc aaggatcttg ttccaaatca   2280

tctttcatat tacctttata atcatgtggc tatgtggccg gaacaaagtg acaaatggcc   2340

tacagctgtg agagcaaatg gacatctcct cctgaactct gagaagatgt caaaatccac   2400

aggcaacttc ctcactttga cccaagctat tgacaaattt tcagcagatg gaatgcgttt   2460

ggctctggct gatgctggtg acactgtaga agatgccaac tttgtggaag ccatggcaga   2520

tgcaggtatt ctccgtctgt acacctgggt agagtgggtg aaagaaatgg ttgccaactg   2580

ggacagccta agaagtggtc ctgccagcac tttcaatgat agagtttttg ccagtgaatt   2640

gaatgcagga attataaaaa cagatcaaaa ctatgaaaag atgatgttta aagaagcttt   2700

gaaaacaggg ttttttgagt ttcaggccgc aaaagataag taccgtgaat tggctgtgga   2760

agggatgcac agagaacttg tgttccggtt tattgaagtt cagacacttc tcctcgctcc   2820

attctgtcca catttgtgtg agcacatctg gacactcctg ggaaagcctg actcaattat   2880

gaatgcttca tggcctgtgg caggtcctgt taatgaagtt ttaatacact cctcacagta   2940

tcttatggaa gtaacacatg accttagact acgactcaag aactatatga tgccagctaa   3000

agggaagaag actgacaaac aacccctgca gaagccctca cattgcacca tctatgtggc   3060

aaagaactat ccaccttggc aacataccac cctgtctgtt ctacgtaaac actttgaggc   3120

caataacgga aaactgcctg acaacaaagt cattgctagt gaactaggca gtatgccaga   3180

actgaagaaa tacatgaaga aagtcatgcc atttgttgcc atgattaagg aaaatctgga   3240

gaagatgggg cctcgtattc tggatttgca attagaattt gatgaaaagg ctgtgcttat   3300

ggagaatata gtctatctga ctaattcgct tgagctagaa cacatagaag tcaagtttgc   3360

ctccgaagca gaagataaaa tcagggaaga ctgctgtcct gggaaaccac ttaatgtttt   3420

tagaatagaa cctggtgtgt ccgtttctct ggtgaatccc cagccatcca atggccactt   3480

ctcaaccaaa attgaaatca ggcaaggaga taactgtgat tccataatca ggcgtttaat   3540

gaaaatgaat cgaggaatta aagacctttc caaagtgaaa ctgatgagat ttgatgatcc   3600

actgttgggg cctcgacgag ttcctgtcct gggaaaggag tacaccgaga agacccccat   3660

ttctgagcat gctgttttca atgtggacct catgagcaag aaaattcatc tgactgagaa   3720

tgggataagg gtggatattg gcgatacaat aatctatctg gttcattaaa ctcatgcaca   3780

ttggagattt atcctggttt cttaggaata ctactactct gattgtgtct actgattggc   3840

tatcagaacc ttaggctgga cctaaataga ttgatttcat ttctaaccat ccaattctgc   3900

atgtattcat aattctatca agtcatcttt gattcctgga cctaataaat tttttttccc   3960

tttctttggg tgtccaagag aaatggtttt tgccaaactc tttttaaaaa acaaattgtt   4020

gctatttcct agaagtttct ggtttttaag atgaacataa aagtgtcagt atgcttcttt   4080

tatgaggtgt actttatact ttgatgaagg ctaaggtgta cctaacagct ttttatagta   4140

tattcattta tggagttagc tgtatttttt tttaaaaaag aaaagtagta aattagcagc   4200

tttttttttt aaatgaagag aacttcatga tgatttaaaa gaactaatga gaatattttg   4260

acttgacttc aattactaag tattttgtat aaagaacaaa taggtcctgc attttataag   4320

actttttaaa gctttaatta ttcaactaag aaccaataat ggcttcttca aggctaatat   4380

caatagttta taagcagtat atttcaccta cactaaatat gggcatttta aaagaagatt   4440

ccccccttcc cccccagaaa tctgcattta ctaaatttgt cttaagtcca attgtgttta   4500

aaggtcatgc tggtcgggtg tggtggctca cacctataat cccagcactt tgggaggcca   4560

aggtgggcag tcacctgagg tcaggagttt gagaccagcc tgaccaacat ggtgaaaccc   4620

cgtctctact aaaaatacaa aaattagctt ggcatggtgg cgggtacctg taatcccagc   4680

tgcttgggag tgtgaggcag gagaatcgct tgaacctggg agaccgaggt tgcagtgagc   4740

tgaaaccgtg ccattgcact ccagcttagg caacaagagt gaaactctgt ctcaatcaat   4800

ccatcaatca atcaataaaa tagaggtcat gctgactatt acagatttaa aaaaaaaaaa   4860

aaaaaaaa                                                            4868


<210>  942
<211>  4735
<212>  DNA
<213>  Homo sapiens

<400>  942
ttggctgggg ctaggcttcc ggggctctgc agtcctcggc gtgtgctggc agcttcggag     60

cccaccgagc cgggcggcta ggatgatgaa ccggacgacc cccgaccagg agctggcgcc    120

agcgtcggag cccgtgtggg agcggccgtg gtcggtggag gagatccgca ggagcagcca    180

gagctggtcg ctggcggccg acgcgggcct actacagttt ctacaggaat tctcacagca    240

aactatctct aggacccatg aaatcaagaa acaagtggac ggactaattc gggaaaccaa    300

agccacagat tgtcgcctgc ataatgtctt caatgacttc cttatgctct ctaataccca    360

gttcattgag aatcgtgtat atgatgaaga agtggaggag ccagtactca aggctgaggc    420

agaaaaaaca gagcaggaga agacacgaga gcagaaagaa gtagatctca ttcctaaagt    480

ccaggaggct gtgaactatg gcttacaagt attggacagt gcctttgagc aacttgatat    540

caaagcagga aactcagact ccgaggaaga tgatgctaat gggcgggtgg aactgatcct    600

tgaaccaaag gatctataca ttgatcgtcc tttaccatat ctcattgggt caaagctgtt    660

catggaacaa gaagatgtag gtcttggaga gctgtccagt gaagaaggct ctgtaggcag    720

tgatcgtggc agtattgtgg acactgagga agagaaagaa gaggaggagt cagatgaaga    780

ttttgcccat catagtgaca atgaacaaaa ccggcacacc acacaaatga gtgatgagga    840

agaggatgat gatggctgtg accttttcgc tgactctgag aaggaggagg aagatattga    900

ggacattgaa gaaaatacta gacctaaaag aagcagacct acatcgtttg cagatgagct    960

ggctgcccgc atcaaggggg atgccgtggg tcgagtggac gaggagccga caaccttacc   1020

ctcaggagaa gcaaaacctc ggaagacact caaagagaag aaggaaagga gaactccttc   1080

agacgatgaa gaggataact tattcgcacc ccccaagctg accgacgagg acttctcgcc   1140

atttggctct ggaggtggcc tgttcagtgg gggcaagggg ctctttgatg atgaggacga   1200

ggagagtgac ctcttcacgg aagcccccca ggatcggcaa gctggagcct ctgttaagga   1260

ggagtcttca tcatccaaac ctggaaagaa aatcccagca ggagctgttt ctgtattttt   1320

aggagacacg gatgtgtttg gtgctgcctc cgttccatca atgaaggagc cacagaagcc   1380

tgagcagccc actccaagga aaagccccta tggtccccct cccactggcc tctttgatga   1440

tgatgatggt gatgatgatg acgacttttt ctcggcaccc cacagcaaac cttctaaaac   1500

aggcaaagtc caatccactg ccgatatctt tggtgacgaa gaaggagatc tgttcaaaga   1560

aaaagccgta gcatcgccag aagccactgt gagtcagaca gatgaaaata aagcaagagc   1620

agaaaaaaag gttaccttat cttccagcaa aaatctcaag ccctcatcag aaacaaagac   1680

tcaaaaaggc ttattttcag atgaggagga ctctgaggat ttgttttctt ctcaaagtgc   1740

gagtaagtta aaaggtgcgt ctctgctgcc tggcaagctc cccacgttgg tttccctgtt   1800

tgatgatgaa gatgaagagg ataatctttt tgggggtaca gctgctaaga agcagacatt   1860

gtgtctacaa gctcagagag aagagaaagc aaaagcctcc gagctctcca aaaagaaagc   1920

atctgccctg ttgttcagca gtgatgagga ggaccagtgg aatattcctg cttcacagac   1980

ccacttagca tctgacagca ggtctaaagg agaacccagg gattctggga ccctccagag   2040

ccaggaggcc aaggctgtga aaaagaccag tctctttgag gaagacgaag aagatgatct   2100

ttttgccatt gccaaggaca gccaaaagaa gacccagaga gtgtcactcc tctttgaaga   2160

cgatgttgat agcggaggct ctctgtttgg ctctcctccc acatctgttc ctcctgcaac   2220

aaagaaaaaa gagactgtct ctgaggcacc acctttgctg ttcagcgatg aagaagagaa   2280

ggaggcacaa cttggagtga agtctgtgga taagaaggtt gagagtgcca aggagtcatt   2340

aaaatttggg agaactgatg tggctgagtc agaaaaggaa ggacttttga ctagatctgc   2400

tcaggaaaca gtcaagcatt ctgatttatt ttcttcatca tccccatggg acaaaggaac   2460

caagcctaga accaaaactg ttcttagctt gtttgatgag gaagaggata aaatggaaga   2520

tcaaaacatt atccaggctc cacagaaaga agtaggaaag ggccgcgatc ctgatgccca   2580

ccccaagagc acaggtgtct tccaggatga agagctgctt ttcagccaca agctccaaaa   2640

ggacaatgac ccagatgttg acctttttgc tggcaccaaa aaaaccaagc tgttagagcc   2700

aagtgttggg agcctgtttg gggatgatga agatgatgat cttttcagct ctgccaagtc   2760

ccagcctttg gtacaagaga aaaagagagt agtgaaaaaa gaccactctg ttgactcttt   2820

caaaaaccag aaacatcctg aatccattca aggtagtaaa gaaaaaggca tatggaagcc   2880

ggaaacacct caggactcat caggtctcgc tccatttaaa accaaagaac catccactcg   2940

gatcgggaag atacaagcaa atttagcgat caacccagcg gccttgctgc ccacagcggc   3000

ttcccagatc tctgaagtaa agcctgtttt gccagaattg gcttttcctt catctgaaca   3060

cagaaggagc cacggtctgg aaagtgtgcc tgtccttccc gggagtgggg aggccggtgt   3120

gagttttgat cttccagctc aggcagacac cttacacagt gcaaacaaga gccgtgtcaa   3180

gatgagaggg aagcgtagac cgcagacccg tgcagctagg cggctggctg ctcaggagtc   3240

cagcgagact gaggacatga gcgtccccag aggacccatt gcacagtggg ctgatggcgc   3300

catttcccca aatggccatc ggccacagct cagagcagcc agtggagaag acagcactga   3360

ggaggccctg gcagctgccg ctgcaccttg ggaaggtggt cctgtgcctg gagtggacag   3420

aagccccttt gcaaagtctc tgggtcattc cagaggggag gctgaccttt ttgattctgg   3480

ggacatcttt tccacgggca ctggatctca gtctgtggag agaacaaaac ccaaggcaaa   3540

gatagcagag aatcctgcca acccaccagt gggtggtaaa gcaaagagcc ccatgtttcc   3600

tgctctaggt gaggccagca gtgatgatga tctctttcag tctgctaaac caaaaccagc   3660

aaagaaaaca aatccctttc ctctcctgga agatgaggat gacctcttta cagatcagaa   3720

agtcaagaag aatgagacaa aatccaatag tcagcaggat gtcatattaa caacacaaga   3780

tatttttgag gatgatatat ttgctacgga agcaattaaa ccctctcaga aaaccagaga   3840

gaaggagaaa acattggaat ctaatttatt tgatgataac attgatatct ttgctgactt   3900

aactgtaaaa ccaaaagaaa agtccaaaaa gaaagtggaa gccaagtcta tatttgatga   3960

tgatatggat gacatcttct cctctggtat ccaggctaag acaaccaaac caaaaagccg   4020

atctgcacag gccgcacctg aaccaagatt tgaacacaag gtgtccaaca tctttgatga   4080

tcccctgaat gcctttggag gccagtagag cacacagggt atccacatgt taccctgcag   4140

ctacattgtt gagttagtga tgatgttgta tatgctgatg gtcttaactg gattacaaaa   4200

agcaaatact agaacagcta gctcatcgtt cacccaatgt acttggtatt tttctgcact   4260

ggtttaatca tgcttaatac tacaaaacaa aaataaatat ttcacagtgg ttggtttgtt   4320

ttgtttttaa accacagttt gatttagtta gccttgctgg ggccataata tgcttcaggg   4380

tgtgtaaaag aagaaatctc tttgtggctt tcatgggcag ggaatcccag agatagcaaa   4440

tgccacctga ccagaagtct ttgttatatg gatgggaacc ctaacttagg gcctgggcag   4500

gggaaagaga aagaaggtga gagattatac ttcatgagtc ttagcaatat gggagcaggt   4560

tttcactgaa ttctgagggt gcctctgcat gtcctccaag gcaaagtttg gcaaactgtg   4620

gcccccccac tgtcatattt tgttaataaa attttattgg aacacaacca caaaaaaaaa   4680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa        4735


<210>  943
<211>  3945
<212>  DNA
<213>  Homo sapiens

<400>  943
gggcgggtgg cgccttggcc tccgcctccg ctcgcctgcg cgcggccctg cgtgaggggg     60

cagaggcgag gtggaggcgt tggcgctgcc acgtctgggc cgcggttccc aactgtggcg    120

cgggcggtgg aggaggaggt ggggctggcg ctgaagccgg atccggatcc ggtgctgtgc    180

acactggtgg gggagagtcc gacgcgcctg gctaggagcg ccgaccgcag ggcctctacg    240

gaccttacta gaaaaatgaa acctgatgaa actcctatgt ttgacccaag tctactcaaa    300

gaagtggact ggagtcagaa tacagctaca ttttctccag ccatttcccc aacacatcct    360

ggagaaggct tggttttgag gcctctttgt actgctgact taaatagagg tttttttaag    420

gtattgggtc agctaacaga gactggagtt gtcagccctg aacaatttat gaaatctttt    480

gagcatatga agaaatctgg ggattattat gttacagttg tagaagatgt gactctagga    540

cagattgttg ctacggcaac tctgattata gaacataaat tcatccattc ctgtgctaag    600

agaggaagag tagaagatgt tgttgttagt gatgaatgca gaggaaagca gcttggcaaa    660

ttgttattat caacccttac tttgctaagc aagaaactga actgttacaa gattaccctt    720

gaatgtctac cacaaaatgt tggtttctat aaaaagtttg gatatactgt atctgaagaa    780

aactacatgt gtcggaggtt tctaaagtaa aaatcttgta agaaaattgt caaaggggct    840

aatgctacaa ggctacactc ttcctagagt tgaaatattt tgttgctgca gccgagtgac    900

ctccataaat actggactga aaaaacattg taatactaca agtataatga catttagaag    960

attactttgg gctggtggga catgctgtga atttagatta caaatgaata ttataaaggg   1020

gatgattttt aaccaaagga atatattttt aacttgaatc ttttcttgca ttgtattttt   1080

ctaaaagttt ggcttccttt cttggtagtc aagagtatgg gtaataagga gttatatgtc   1140

tgctatctgt gttgctcatt taaaaaaagt atacattgaa taaggctgtt tatcacatgc   1200

ataaaattaa atatttttgt ttcaaagaaa catctcaata cacttagggg tgtattgttt   1260

cccacatatt aagtcagggt ggataaatta gttattataa ctaaacatag tatagtccaa   1320

cattcgttga tcccaataca ggcaaacaac ctggtcaacc ttttgaagta gaagaaatga   1380

aaattacttg acaagattaa aagtaaaaca atttaaatgt tttactgaaa gtttatatag   1440

tatagtctat gtagataaaa agtaccactt gtcttttctg tgaattatga ctattcattt   1500

gttaaaaata cctaagagca attatagtgg gacatctaag gtcctctgta aacagtgaat   1560

tagcaaacct cagcctatgt gtttctaccc tgattttttt cttttcatgg gtatctgaag   1620

cctctaagtt ttttcaaaaa tggagtatca caaaattgag tgaaacacaa tacttaatgt   1680

attgtactag attgccaaat tcataaaatg ttaatggaag ctttttgatg tgattataat   1740

ggcactattc tggtcattat cctattttga ttttatttaa ttttttaaag ttgaagaatt   1800

aaatatttta atggttctaa tcttttgcat tccatgttgc attaaacctg tttatatgag   1860

tagtcttctg ttagaatcac atctgtgctt ttcttgagtc tgctgttgaa ctattagatt   1920

aagtcataat tcataaaatt ttagtttaat gtgctctttg taaaatgaaa ttgtaaagaa   1980

aataccagtg tttctcatcc cattgactca caccacgtca tctggatttt ggatttccct   2040

ccatgcagcc agctatagtt ggctttccaa aacaacagaa atccttcacc aatagagtgc   2100

actacttacc tgcttatagc ctatacagac gaactgatct gtccttcgtg aaacgcaaca   2160

aagctagttc tgtcttttca gaagtcctac aaccttgaca aagagtagtt ttatcaggta   2220

aatcctggta attaaaaacg catgttttta aaaattagcc tggtaaggcc gggtgcagtg   2280

gctcacgcct gtaatcccag cactttggga ggctgaggtg ggcagatcac aaggtcagga   2340

gtttgagacc agcctgacca aaatggtgaa accctgtctc tactaaaaaa aagaaaaatt   2400

agccagacgt ggtggcatgc gcctgtaatc ccagctactc aggaagctga ggcgagagaa   2460

tcgcttgaac ccgggaggca aaggttgcag tgagctgaga tcacaccact gcactccagc   2520

ctggcgacag agagagactc catctcaaaa caaaacaaaa aaaattagcc tacttaaagg   2580

cacaactaaa tgctttatta cctttcttac cactgaacaa tttgaggtaa aatcattcac   2640

aaggttggca cttcagtaaa tccctttaaa tagtgttcct aagatatctc ttaaatcctc   2700

ccataggaaa tagaattaca ggtaaggtac accatacaaa aattgtgtca ttgaggacaa   2760

tggtgatctg taattttagt tgagtatgtt tatgattttt gaagccatat ggtgagtaaa   2820

tgtaaatatg aaaaaagtgc tacataaaac acttcttaaa cttttttttt ttaaaaactg   2880

ctccttgtgg agcaggacta ccccataggc agtgtaccca caatagatag ccttttgttg   2940

ttgttgttgt tgagacaagg tctcgctgtt gcccaggcta gagcgcaggg gcacaatcac   3000

cacacactgc cgcttcaatc tcctgggctc aaatgatcct tccacctcag cctcccatgt   3060

ggctgggact ataggtgcat gccaccacac ccagctaatt aaaaaaattt tttgtgtgga   3120

gtctatgttg cccaggctgg tctcttaact cctaggctca agtgatcctc ccacctcagc   3180

ctcccaaagt gcttggatga caggtgcgag ccactgcacc tggcccacat tttttaaaga   3240

gacactgtcc cactccatca cccaggctgg agtccagtgg tgtgatcata gctcactgca   3300

tcctccagtt cctgggttca agccatccct cctgcctcag cctccccagt agctggaact   3360

acaggtgtgt gccatcacac ctggctttac atttttctgt ggggtcttac tatattgccc   3420

aagccggtct caaactcctg agctcaagtg atcctctgcc tcagcctcca gagtatctgg   3480

gattacatat gtcggctacc gtgtctggcc gttcacatct ttggccacta tttgcttgtg   3540

aaaaggtata atgaggtggt acttatcatt tttactgtgt ctcatgtttt gtatattttt   3600

gtttcatcaa ctaagatgca ctgtaacatc tctgaaatct ggatatatta tcaatggttt   3660

atcatagttt tgttagcaat acactgtctt ttagtggtgc ctaaaataat ggtatagttg   3720

tgaggtgatc ttagatttga tgaagcacag tatgcaggta ggcctaatgg gggaagatgg   3780

taatataaaa gcaagaagta tttttttttt gtaatgactg aaagctgttc tgtggatgac   3840

ctaccctttc ctttaaacac gattctctca cttccaactc caaacttgct caactaatcc   3900

ttaaaaataa acttgagctg gaatttgaaa aaaaaaaaaa aaaaa                   3945


<210>  944
<211>  2317
<212>  DNA
<213>  Homo sapiens

<400>  944
cggacgcgtg ggtgagcagg gacggtgcac cggacggcgg gatcgagcaa atgggtctgg     60

ccatggagca cggagggtcc tacgctcggg cggggggcag ctctcggggc tgctggtatt    120

acctgcgcta cttcttcctc ttcgtctccc tcatccaatt cctcatcatc ctggggctcg    180

tgctcttcat ggtctatggc aacgtgcacg tgagcacaga gtccaacctg caggccaccg    240

agcgccgagc cgagggccta tacagtcagc tcctagggct cacggcctcc cagtccaact    300

tgaccaagga gctcaacttc accacccgcg ccaaggatgc catcatgcag atgtggctga    360

atgctcgccg cgacctggac cgcatcaatg ccagcttccg ccagtgccag ggtgaccggg    420

tcatctacac gaacaatcag aggtacatgg ctgccatcat cttgagtgag aagcaatgca    480

gagatcaatt caaggacatg aacaagagct gcgatgcctt gctcttcatg ctgaatcaga    540

aggtgaagac gctggaggtg gagatagcca aggagaagac catttgcact aaggataagg    600

aaagcgtgct gctgaacaaa cgcgtggcgg aggaacagct ggttgaatgc gtgaaaaccc    660

gggagctgca gcaccaagag cgccagctgg ccaaggagca actgcaaaag gtgcaagccc    720

tctgcctgcc cctggacaag gacaagtttg agatggacct tcgtaacctg tggagggact    780

ccattatccc acgcagcctg gacaacctgg gttacaacct ctaccatccc ctgggctcgg    840

aattggcctc catccgcaga gcctgcgacc acatgcccag cctcatgagc tccaaggtgg    900

aggagctggc ccggagcctc cgggcggata tcgaacgcgt ggcccgcgag aactcagacc    960

tccaacgcca gaagctggaa gcccagcagg gcctgcgggc cagtcaggag gcgaaacaga   1020

aggtggagaa ggaggctcag gcccgggagg ccaagctcca agctgaatgc tcccggcaga   1080

cccagctagc gctggaggag aaggcggtgc tgcggaagga acgagacaac ctggccaagg   1140

agctggaaga gaagaagagg gaggcggagc agctcaggat ggagctggcc atcagaaact   1200

cagccctgga cacctgcatc aagaccaagt cgcagccgat gatgccagtg tcaaggccca   1260

tgggccctgt ccccaacccc cagcccatcg acccagctag cctggaggag ttcaagagga   1320

agatcctgga gtcccagagg ccccctgcag gcatccctgt agccccatcc agtggctgag   1380

gaggctccag gcctgaggac caagggatgg cccgactcgg cggtttgcgg aggatgcagg   1440

gatatgctca cagcgcccga cacaaccccc tcccgccgcc cccaaccacc cagggccacc   1500

atcagacaac tccctgcatg caaaccccta gtaccctctc acacccgcac ccgcgcctca   1560

cgatccctca cccagagcac acggccgcgg agatgacgtc acgcaagcaa cggcgctgac   1620

gtcacatatc accgtggtga tggcgtcacg tggccatgta gacgtcacga agagatatag   1680

cgatggcgtc gtgcagatgc agcacgtcgc acacagacat ggggaacttg gcatgacgtc   1740

acaccgagat gcagcaacga cgtcacgggc catgtcgacg tcacacatat taatgtcaca   1800

cagacgcggc gatggcatca cacagacggt gatgatgtca cacacagaca cagtgacaac   1860

acacaccatg acaacgacac ctatagatat ggcaccaaca tcacatgcac gcatgccctt   1920

tcacacacac tttctaccca attctcacct agtgtcacgt tcccccgacc ctggcacacg   1980

ggccaaggta cccacaggat cccatcccct cccgcacagc cctgggcccc agcacctccc   2040

ctcctccagc ttcctggcct cccagccact tcctcacccc cagtgcctgg acccggaggt   2100

gagaacagga agccattcac ctccgctcct tgagcgtgag tgtttccagg accccctcgg   2160

ggccctgagc cgggggtgag ggtcacctgt tgtcgggagg ggagccactc cttctccccc   2220

aactcccagc cctgcctgtg gcccgttgaa atgttggtgg cacttaataa atattagtaa   2280

atccttaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa                            2317


<210>  945
<211>  1479
<212>  DNA
<213>  Homo sapiens

<400>  945
aaacgccgag cgagcgaggg agaggcacag tcagagggaa cgcccgcgcg gggagccagg     60

ggcgcccgac cccgccgccg ccgcagcggc gcgcagcccc cgacgcgccc tgtggggacc    120

cggaccagga gggaccctgc cccgggaaaa ggctgtggag acctgggctc cgaccccagt    180

tcatcccccc acacccccgc cgccccgtgc caccctggtc cgcgctggga accctatcct    240

gcccctcgtg tcagcccggc actggccaga atcgcgggca tggcggtgac catgctgcag    300

gactggtgcc ggtggatggg ggtcaacgct cgcaggggcc tgctcatcct gggcatcccg    360

gaggactgtg atgatgccga attccaagag tccctcgagg ctgccctgag gcctatggga    420

cactttacag tgctaggcaa agtgtttcga gaggaggata atgccaccgc ggccctggtc    480

gagctcgacc gggaagtcaa ctatgctttg gtccccaggg aaatccccgg cactgggggc    540

ccgtggaacg tggtctttgt gccccgttgc tcaggcgagg agtttctcgg tctcggtcgc    600

gtgttccact tcccggagca agaggggcag atggtggaga gcgtggccgg cgccctgggt    660

gtggggctgc gcagggtgtg ctggctgcga tccatcggtc aggcggtcca gccctgggtg    720

gaggccgtga ggtaccagag cctgggcgtg ttttccggga gggaccagcc agccccaggg    780

gaggagtcct ttgaggtctg gctagaccac accaccgaaa tgctgcatgt gtggcagggg    840

gtctcggaaa gggagaggag gaggaggctg ctggaaggct tgcgtgggac cgccctgcag    900

ctcgtgcacg cgctcctggc ggagaacccc gccaggacgg cgcaggactg tctggcggcc    960

ctggcccagg tgtttggaga caacgagtcc caggcgacca tccgggtgaa gtgtctgacc   1020

gctcagcagc agtcaggcga gcgtctctca gctttcgtgt tgcggctgga agtgctgctg   1080

cagaaggcca tggagaagga ggccctggcc agagcatccg ccgaccgcgt gcgcctgagg   1140

cagatgctca ccagggccca ccttactgag cctctggatg aagcactgag gaagctgaga   1200

atggccggga ggtctccaag tttcttggag atgctggggc tcgttcggga gtctgaggca   1260

tgggaggcca gtctagccag gagcgtgaga gcccagacac aggaaggggc cggtgcccgg   1320

gctggtgccc aggctgttgc cagagccagc actaaagtag aggcggtccc aggaggtcct   1380

ggtcgggagc cagagggcct ccgccaggca ggaggccagg aggctgagga gctcctccag   1440

gaggggctca agcccgtcct ggaggaatgt gataactag                          1479


<210>  946
<211>  500
<212>  DNA
<213>  Homo sapiens

<400>  946
cagcgccttg ccttctctta ggctttgaag catttttgtc tgtgctccct gatcttcagg     60

tcaccaccat gaagttctta gcagtcctgg tactcttggg agtttccatc tttctggtct    120

ctgcccagaa tccgacaaca gctgctccag ctgacacgta tccagctact ggtcctgctg    180

atgatgaagc ccctgatgct gaaaccactg ctgctgcaac cactgcaacc actgctgctc    240

ctaccactgc aaccaccgct gcttctacca ctgctcgtaa agacattcca gttttaccca    300

aatgggttgg ggatctcccg aatggtagag tgtgtccctg agatggaatc agcttgagtc    360

ttctgcaatt ggtcacaact attcatgctt cctgtgattt catccaacta cttaccttgc    420

ctacgatatc ccctttatct ctaatcagtt tattttcttt caaataaaaa ataactatga    480

gcaacataaa aaaaaaaaaa                                                500


<210>  947
<211>  4490
<212>  DNA
<213>  Homo sapiens

<400>  947
aaactttacc cggcctaaca gctgaggcgc tttacggcga cggcggctga gtgagaacct     60

tggcggctgt ggaggctgcc gcggctgcga aggaggcggc ggcggtggcg gaggaagagg    120

agtggcggca gcggcggcgg ggacccgtgc ggggatggcg gaggtaccgc ctgggcctag    180

cagcctcctc ccaccaccag cacctccggc cccggcggcg gtcgagcccc gctgtccctt    240

cccggcgggg gccgccctcg cctgctgcag cgaggacgag gaggacgacg aagagcacga    300

aggcggcggc agcaggagcc cggcgggcgg agagtcggcg acggtggcgg ccaaggggca    360

tccgtgcctc cgctgccctc agccgccgca ggagcagcag cagctcaacg gattgattag    420

ccccgaactg cggcacctcc gggcggccgc ctccctcaag agcaaggtcc tgagcgtagc    480

agaggtggcc gcgaccacag ccacccctga cggaggcccc agagcgactg caacaaaagg    540

agccggggta cactcgggcg agaggccccc tcactccctc tctagtaatg caagaactgc    600

ggtccccagc ccggtggagg cagcggcggc gagcgatccc gcggcggccc gcaatggact    660

ggccgagggc accgagcagg aggaggagga ggaagacgag caggtgcggc tgctgtcttc    720

gtccctgacc gccgactgca gcttaagaag cccttcgggc agggaggttg agcctgggga    780

ggatcggacg atacgatatg tccgatatga atccgagcta caaatgcccg atatcatgag    840

actgatcacc aaagatctgt ccgaacccta ctccatttat acctatagat attttatcca    900

caactggcca cagctgtgct tcttggccat ggtaggggag gagtgtgtag gtgccatcgt    960

ttgcaagttg gatatgcaca aaaagatgtt ccgcagaggt tatatagcca tgttagccgt   1020

ggattccaaa tacaggagaa atggcattgg tactaacttg gttaagaaag ctatatatgc   1080

catggttgag ggagactgtg atgaggttgt tttggaaacc gaaataacaa ataagtccgc   1140

tttgaaactt tatgaaaatc ttggttttgt tcgagataag aggctgttca gatactattt   1200

aaatggagtt gatgcactgc gacttaaact gtggctgcgt tgagaaactg acatcaagga   1260

acaactatca tccgcacaga atcgaccttt gcatgcaatg caatttgtac agaattgctt   1320

tgcaggtgga tttagtaatt tccatgcagc tcttacctgt cagtgtctca ttgagtgtcg   1380

cacaatattt gttgcacttt ggcatggcac atttgttctg aattaaaaga ttgttttaaa   1440

cttcaggagt tcttttggta ccaacaagat gtgccagttg atagccaaga tttatgtgtt   1500

catttgcaaa gtctgctgac aatgttattt acacagtgat cattttatca cagaaccagt   1560

aagtggaaca taatttttgt tccttaaaaa agccaatgtg gattgtaaaa gtctttaagt   1620

atactaacat ttcacacaaa acctgcccta gttttctgaa gtgggtgagg gagacgcttc   1680

agttttaggt tttatttttt caatattaaa ttttccattc ttgaatattg gtacctcagt   1740

gattagtgaa tgaaaaaaat gtagggtggg tatgtcttac aatgagtaaa ggtaacaatt   1800

aaattttgtc tgccagtgcc tgtgtagata agtatatttg tcttcatctc tagtttttga   1860

atgcatgcta tcttttcctt ttctttaagg cctttgcaag caaacttttg tttttattta   1920

aattctaaat ttgataaatt atttcagatt tttataattt ggatactttt ttcaggtgaa   1980

tgaaagaatg gtttacttta gaagtccctt tttccttaca gtaacaagtt gaatctactt   2040

ggaaaattga gaaatggctc aaaagagata agaaaagttg atggagccgg gaattgctgg   2100

ggtttagatg cactttttct tttgagagta agggaagttt tggaaaagaa tagaaaatta   2160

gtgtaagttg atatgatttt atttaatcaa aattactgct acgctgcgaa gaacagcttt   2220

tacaaagtag ctgaatttgt ttttcccact tgatttggat tcacattgct ttcatttctt   2280

aaaatgcttc acttcaggtt cttggtcttg gaaataaatt tcaaggtgca ttgtatccat   2340

tttaagctgc tttattttat tttcacttgt atgagcaaat tcttggggga gctttgcttt   2400

tcttctgcca gaaaaacaaa agggggaaat gaaaatcttt tttggaatga gttctgtggg   2460

ttttcttaac agccaccatg tttattagtt acattgtgtt ttggccaatc agtgcaatgt   2520

aacaaatttt acagttaatt gctttcaatt gagtcagtaa acctgtgata gataatttat   2580

ttaactggaa aacctaggta cccataagaa aaaagattca ttctctgtga aaactgtagg   2640

aatctgttgt tgttttcatt tgaatatgct ctacttctgc tctagtattt ggtttggaat   2700

atattttgtg gctctaatta ctgtattttt aaaaacccta cctccattaa cagttggtaa   2760

aggccccttt tcaggaaagt ttgttgcttt tttttttttt ttaaaggaaa gctgctcttt   2820

gctcagtata gtgttttgaa agtgaacata gtaacaaata ctttaaaaat aaagatacac   2880

aatttatatt tgaaaataaa aactttctgc tggtgggatt atttatagtt ctttattttt   2940

aaagaaaatg ttttcctttt tatattgctc ttgaaagttt aatgagcaga atacaatact   3000

ggttataata aaaatatggt aaccacacag tactcagcct ttcaatatgt ttttggtcaa   3060

acttcattta ggcactagca tttagaagaa taccaatcac agtgatgctt ttgttattta   3120

atatgaagga aatggaacta aaacatttat gtcatcaaat tttatttcac ttctttatat   3180

ttgacttgct ggttgataca taatggttga tgaacatata tttgcttaaa tcactaatag   3240

ggatggttgt aaagtagata gatcattggt tcaaccattt tagtgttttt gccagattgt   3300

caatgaaacc atcatactga ccttttcctc caaaattgcc aaattgactg aactggttgg   3360

gtgtttgtaa agatgacgtt aactgtgtga ctaaaaagtc agatggttgc catattgttt   3420

ggaatatgtt gaatgtcagt gtatgcctta tgtctttaat tgggtatgca aaaaaatttt   3480

tacttaagta gattaaaatt ttaacctcta gcatgaaaac ccagcaccaa cactgaaaga   3540

ctccattcag gttgaagtag cctcaaacag taatttactt tttgataata ggctgttgtt   3600

tttcttaaat aagcttaaaa caattctatc tgaaattggt agcatgggtt cacttggcta   3660

caactgagca aaatagatgc aactttcttt taatggggtg ctgcctcttt aggactgact   3720

gtactatcca ctgacactgg tttggcagtt ggtactgctg aacattttta tacatgctac   3780

catgaagcta tatatgttag tattgaagaa gctaacgggt atactatcat ttttgatgtg   3840

tgggctgatt ataatttcct gtatttcctg tacattggga tgaaactact ttagcaaagt   3900

ccacagatca gaaaccagac ggtagttttt gaagttgaaa ccagcaaaat aagaaaaaat   3960

aaaaaatcga ttttaatatt ttctgcctct ttcccaaatt acccttccca cttgctcgac   4020

aaatctatgt aaagcagttt gttttttcat gttttaactt taccttgccc tgtgttatgg   4080

tactggctga catgtctaag actggatgtg tatatttatt atggtgtcta aaaatcatga   4140

agttcatcac ttttcaggag tatagataaa atcaaattgg tagtacatca gagttacttt   4200

tcagtgcacc atgacatcac taaaatgagt gctgtaatgt tacagggctt tcaggtttgt   4260

aaaaacataa ccataaatta tattgacgtc agatatgagt tgagtatcta taaaatatca   4320

cgtgtatctc aaaatattgg actgctgttt gactggatat tgctgcataa ttttcttcta   4380

ttgtcccata tccttttgga gagagattta atgggatttg aaatgtgcaa gctgtctaaa   4440

taagatgcag tcaaataaag tatggttaag ttgtgaaaaa aaaaaaaaaa              4490


<210>  948
<211>  5156
<212>  DNA
<213>  Homo sapiens

<400>  948
tgttttgggc tccgtgagcc gaaaggggga ggggagacga aggagaagca aacactgcgc     60

agcgggaccg tgcgcggcct ccgctcctgc gtgcgtgcgc tcgctcgcgc gggctcagtg    120

ctggcgcgtg aggcggaggc gggcggcggc ggcggcgcct gcgcggtcgg actcggtcga    180

cggttcgcag gggaggaggc ggcgggaggc ggaggaggcg gcggcggcga tggaggtgaa    240

gcggctgaaa gtgaccgagc tgcggtcgga gctgcagcgg cggggcctgg actcgcgcgg    300

cctcaaggtg gatctggcgc agcggctgca ggaggcgctg gacgccgaga tgctcgagga    360

cgaggccggc ggcggcgggg ccgggcccgg cggggcctgc aaggcggagc ctcggcctgt    420

ggccgcgtcg ggcggcggcc cgggcgggga cgaggaggag gacgaagagg aggaggagga    480

ggacgaggag gcgctgcttg aggacgagga cgaggagcca ccccctgctc aagccttggg    540

tcaggccgcg cagccgccgc cggagccccc ggaggcggca gccatggagg ccgcggccga    600

gccagatgct tccgagaagc cggcggaggc cacggccggg tcaggcgggg taaatggtgg    660

cgaagagcag ggcctcggca agagggagga agacgaaccc gaggagcgga gcggggacga    720

gacgccggga tccgaggtgc cgggtgacaa ggccgccgag gaacagggag atgaccagga    780

tagtgaaaag tcaaaaccag caggctcaga tggtgagcgg cggggggtaa agagacagcg    840

ggatgagaag gatgaacatg gccgagctta ctatgaattc cgagaggagg cttaccacag    900

ccgctcaaag tctccactgc ctcctgaaga agaggcaaaa gatgaggagg aggatcaaac    960

tcttgtgaac ctggacacgt atacctcgga tctgcatttt caagtgagca aagaccgcta   1020

tggagggcag ccacttttct cagagaagtt ccccaccctt tggtctgggg caaggagtac   1080

ttacggagtg acaaagggaa aagtctgctt tgaggcaaag gtaacccaga atctcccaat   1140

gaaagaaggc tgcacagagg tctctctcct tcgagttggg tggtctgttg atttttcccg   1200

tccacagctt ggtgaagatg aattctctta cggtttcgat ggacgaggac tcaaggcaga   1260

aaatggacaa tttgaggaat ttggccagac ttttggggag aatgatgtta ttggctgctt   1320

tgctaatttt gagactgaag aagtagaact ttccttctcc aagaatggag aagacctagg   1380

tgtggcattc tggatcagca aggattccct ggcagaccgg gcccttctac cccatgtcct   1440

ctgcaaaaat tgtgttgtag aattaaactt cggtcagaag gaggagccct tcttcccacc   1500

accagaagag tttgtgttca ttcatgctgt gcctgttgag gagcgtgtac gcactgcagt   1560

ccctcccaag accatagagg aatgtgaggt gattctgatg gtgggactac ccggatctgg   1620

aaagacccag tgggcactga aatatgcaaa agaaaaccct gagaaaagat acaatgtcct   1680

gggagctgag actgtgctca atcaaatgag gatgaagggt ctcgaggagc cagagatgga   1740

ccccaaaagc cgagaccttt tagttcagca agcctcccag tgccttagta agctggtcca   1800

gattgcttcc cggacaaaga ggaactttat tcttgatcag tgtaatgtgt acaattctgg   1860

ccaacggcgg aagctattgc tgttcaagac cttctctcgg aaagtggtgg tggttgtccc   1920

taatgaggaa gattggaaga agaggctgga gttgaggaag gaagtagagg gagatgatgt   1980

gcctgaatct ataatgctgg agatgaaagc caacttctct ttgcctgaaa aatgcgacta   2040

tatggatgag gtgacatatg gggagctgga gaaggaggaa gctcagccca ttgtcactaa   2100

gtacaaggag gaggcaagga agcttctgcc cccctccgag aagcggacaa atcgccgaaa   2160

caaccgaaac aagcgtaacc ggcagaaccg aagccggggc caaggctatg tgggcgggca   2220

gcgccgaggc tacgacaacc gggcctacgg gcagcagtac tgggggcagc ctggaaacag   2280

agggggttac cgtaatttct atgatcgata caggggagac tatgatcgat tttacgggcg   2340

agattatgag tacaacagat acagagacta ttacagacaa tacaatcggg attggcagag   2400

ttactactac caccaccccc aggacagaga ccgatactac aggaattact acgggtacca   2460

agggtatcgg tgaagcccct gccatggtca cctgtcagcc atgaagctga atctctgggg   2520

gtgccaggca cccccgcaaa acacaaccaa ggaaaacagg ggctgtcggg gtggggctga   2580

gctgccgggg aggggtggtg gggggggagg gtgctcaagc aggggtgggg gaggggggag   2640

gtggaaacaa acaacaaaac tgtacatttt ttttaaagtt tgttgaaaag aatattgtct   2700

tattctataa aacatttcaa acctagttag agatttgtaa tcaaaaaaca tttgcgcaga   2760

aagcagcact tagggctgcc tgttctatac cctacagtca gacaggaaaa gaactgaaaa   2820

tggcaccctt ctgacattct gaggcagctg gactggcagc caagtaaagg agagtgatga   2880

ggtggtgtgg ggagggtggg gaggcagcgc gagggtgctc tccacagcag gtaggagcag   2940

gcaggagtgg ggacagaggg agagcttgtg actgggacag tgaaaataaa cgattggctc   3000

ttatcaatca cttgcaccaa ctaaccgttt gtattttctt taccgacctt tcccttttgg   3060

gatatgtggt ctggtgggct gggaggctta cagtgtccca actctccatt ttcctgtgcc   3120

tttgtgctgt ttggctgagg catggagact gccagtgggt ggttctattt tacaggattc   3180

ccaggccaag aaagcctggg gactgtcctt gatggcagag cagaatagcc tgccccttct   3240

atagacccat tgattaattc ctgtaaaatc ttggggagaa tgggattgca gccctcagcc   3300

taaagattgt gatttgccag tctctagtct ctgtcttcca aggttgagag aggtgggagg   3360

tctctgaaat catccctgtt agagtgtctg tcctcttaca gtgcgagaga aggaacgttt   3420

ctcagggttt cagctcacac gaaaacacag caggattctt ttcactgcag cgggatatgt   3480

atataggtga atcctgtggt gtgggctcac aggcccaggt gctgagaata gcaactagca   3540

actattttct acagtgtgga gggctcgtgc cctgctggtt tttttgatac acaggtagag   3600

aatgaataga agaggggagg gtggtggggg ggggtgggag gcagctcagt ggggctgctg   3660

aaccttggga agagtgtgag tgtgaacgtg tgtaaatgtg cgtgtgaaag ggagcacccc   3720

ttcccgactt ctagaaacaa aattcctttt ggggcgcttt ccctgtgtgt ccccagagag   3780

gcctctagcc aggagccttc agttgggata gtttcatttg tgactttacc aataccctcc   3840

cagttcttga tagacagctg taggttgctg ggttcaagaa tatgggtggg atatggaatg   3900

ctctttcaat gtctagcttc agttttcatt catcctcctg ctcagcactg tcagccaaga   3960

gcttactcag cagacaccac atactgcagc agttcctagt gagaaaatct gtgccactag   4020

aaaatgcttc acttccattt cctcacctgg gcagttctct gtttaaaatt gtgggctgat   4080

ttggtcttcc tctcctcctc ccactgttac tgccctgcag cccttgttca ggtgtacaga   4140

cccttattct ggcctctagt gtccttgtct gtcatgacac acccttccgc ccaaatacct   4200

ctgaccccaa ggctggaatg gggctggtag gagataagtt tgcttactca tagtcatgtc   4260

ctttctcttg gcacctgctt ccctgcggtg tcctcaaatg gatttctgtg tggcagtgga   4320

gtgattgcat gaatttttct gtaacacatt aactttgtat tattattaag ggagtttgag   4380

aaagctttgc ttataatgtc aaggcaagga ggtaaaaact ggagcccaaa gaaattccct   4440

tagggcaaga ttatgttata atagaaaatt gaatttcctg aggcagtggc tgccacccct   4500

tttcagatgt ttagtcctgc aaatagcatc tttcttgtag tctgtgacat ggatggggat   4560

gctagggccc ttaggggcaa ggggactaaa ctaaatcaag ttgagttttt ttccagcagg   4620

ggttagggga ggtactcgct gttgatattt gacactagaa agtaatcttt tttacaaaac   4680

tgtttttcta ggtgggtgga aagtgaaact gccacatcct tgttggttta gtccaagaga   4740

tcatttgcaa caacagtaga tgtccgggtt ttgtttctgt ctttttatta tgaaaaacta   4800

tgttaagggg gaaaatgtgg attatggtaa ccagaggaat ccctagcctt gttttcctta   4860

gaagacttgt ttagtgtttt atcagacgtc tgttgtagtt gtagacagga aagcttgtga   4920

gaaaaacacc acatggagcc tgtaaatgtt tttgcacaac ctgtaaagca ttcttggaag   4980

tggccagtaa aaaggggttt taccatttaa aaaaaaaatg taactgtgtc attgtttaca   5040

tctgtaactt tttcctcccc tgttctcatt acaccattct ggcgaaaatg taggcaaagt   5100

agcttccagt tttagaataa ataaccattt ggattgaatt caccctaaaa aaaaaa       5156


<210>  949
<211>  554
<212>  DNA
<213>  Homo sapiens

<400>  949
atacagtgac ctcgggcggc gggtcacgtc ggccgggcat ggctgcatgg agcccggccg     60

cggcagcgcc tctcctccgc gggatccgcg ggcttccact tcaccatcgg atgtttgcca    120

ctcagactga gggggagctc agagtgaccc aaattctcaa agaaaagttt ccacgagcta    180

cagctataaa agtcactgac atttcaggag gttgtggggc gatgtatgaa attaaaattg    240

aatcagaaga atttaaggag aagagaactg tccagcagca ccagatggtt aatcaggcac    300

taaaagaaga aatcaaagag atgcatggat tgcggatatt tacctctgtc cccaaacgct    360

gaccacgccc tggctgcata gatgctgctg cttaagacct tggatgaact tcactgacat    420

cattcttccc taagcagtca ccaaaaaatt tatatatttt gctcatatac atttccatat    480

tataattata gaagatgtat aatctattta gatgttaatt aaaggaaaca aacaactgaa    540

gcttttgaag ggtc                                                      554


<210>  950
<211>  2689
<212>  DNA
<213>  Homo sapiens

<400>  950
tttattctct ggaacatgaa acattctgtt gtgctcatat catgcaaatt atcactagta     60

ggagagcaga gagtggaaat gttccaggta taaagaccca caagataaag aagctcagag    120

tcgttagaaa caggagcaga tgtacagggt ttgcctgact cacactcaag gttgcataag    180

caagatttca aaattaatcc tattctggag acctcaaccc aatgtacaat gttcctgact    240

ggaaaagaag aactatattt ttctgatttt ttttttcaaa tctttaccat tagttgccct    300

gtatctccgc cttcactttc tgcaggaaac tttatttcct acttctgcat gccaagtttc    360

tacctctaga tctgtttggt tcagttgctg agaagcctga cataccagga ctgcctgaga    420

caagccacaa gctgaacaga gaaagtggat tgaacaagga cgcatttccc cagtacatcc    480

acaacatgct gtccacatct cgttctcggt ttatcagaaa taccaacgag agcggtgaag    540

aagtcaccac cttttttgat tatgattacg gtgctccctg tcataaattt gacgtgaagc    600

aaattggggc ccaactcctg cctccgctct actcgctggt gttcatcttt ggttttgtgg    660

gcaacatgct ggtcgtcctc atcttaataa actgcaaaaa gctgaagtgc ttgactgaca    720

tttacctgct caacctggcc atctctgatc tgctttttct tattactctc ccattgtggg    780

ctcactctgc tgcaaatgag tgggtctttg ggaatgcaat gtgcaaatta ttcacagggc    840

tgtatcacat cggttatttt ggcggaatct tcttcatcat cctcctgaca atcgatagat    900

acctggctat tgtccatgct gtgtttgctt taaaagccag gacggtcacc tttggggtgg    960

tgacaagtgt gatcacctgg ttggtggctg tgtttgcttc tgtcccagga atcatcttta   1020

ctaaatgcca gaaagaagat tctgtttatg tctgtggccc ttattttcca cgaggatgga   1080

ataatttcca cacaataatg aggaacattt tggggctggt cctgccgctg ctcatcatgg   1140

tcatctgcta ctcgggaatc ctgaaaaccc tgcttcggtg tcgaaacgag aagaagaggc   1200

atagggcagt gagagtcatc ttcaccatca tgattgttta ctttctcttc tggactccct   1260

ataatattgt cattctcctg aacaccttcc aggaattctt cggcctgagt aactgtgaaa   1320

gcaccagtca actggaccaa gccacgcagg tgacagagac tcttgggatg actcactgct   1380

gcatcaatcc catcatctat gccttcgttg gggagaagtt cagaagcctt tttcacatag   1440

ctcttggctg taggattgcc ccactccaaa aaccagtgtg tggaggtcca ggagtgagac   1500

caggaaagaa tgtgaaagtg actacacaag gactcctcga tggtcgtgga aaaggaaagt   1560

caattggcag agcccctgaa gccagtcttc aggacaaaga aggagcctag agacagaaat   1620

gacagatctc tgctttggaa atcacacgtc tggcttcaca gatgtgtgat tcacagtgtg   1680

aatcttggtg tctacgttac caggcaggaa ggctgagagg agagagactc cagctgggtt   1740

ggaaaacagt attttccaaa ctaccttcca gttcctcatt tttgaataca ggcatagagt   1800

tcagactttt tttaaatagt aaaaataaaa ttaaagctga aaactgcaac ttgtaaatgt   1860

ggtaaagagt tagtttgagt tactatcatg tcaaacgtga aaatgctgta ttagtcacag   1920

agataattct agctttgagc ttaagaattt tgagcaggtg gtatgtttgg gagactgctg   1980

agtcaaccca atagttgttg attggcagga gttggaagtg tgtgatctgt gggcacatta   2040

gcctatgtgc atgcagcatc taagtaatga tgtcgtttga atcacagtat acgctccatc   2100

gctgtcatct cagctggatc tccattctct caggcttgct gccaaaagcc ttttgtgttt   2160

tgttttgtat cattatgaag tcatgcgttt aatcacattc gagtgtttca gtgcttcgca   2220

gatgtccttg atgctcatat tgttccctat tttgccagtg ggaactccta aatcaagttg   2280

gcttctaatc aaagctttta aaccctattg gtaaagaatg gaaggtggag aagctccctg   2340

aagtaagcaa agactttcct cttagtcgag ccaagttaag aatgttctta tgttgcccag   2400

tgtgtttctg atctgatgca agcaagaaac actgggcttc tagaaccagg caacttggga   2460

actagactcc caagctggac tatggctcta ctttcaggcc acatggctaa agaaggtttc   2520

agaaagaagt ggggacagag cagaactttc accttcatat atttgtatga tcctaatgaa   2580

tgcataaaat gttaagttga tggtgatgaa atgtaaatac tgtttttaac aactatgatt   2640

tggaaaataa atcaatgcta taactatgtt gaaaaaaaaa aaaaaaaaa               2689


<210>  951
<211>  553
<212>  DNA
<213>  Homo sapiens

<400>  951
cgcccacgtg aagaacgcca gggagctgtg aggcagtgct gtgtggttcc tgccgtccgg     60

actctttttc ctctactgag attcatctgt gtgaaatatg agttggcgag gaagatcgac    120

ctatcggcct agaccaagac gctacgtaga gcctcctgaa atgattgggc ctatgcggcc    180

cgagcagttc agtgatgaag tggaaccagc aacacctgaa gaaggggaac cagcaactca    240

acgtcaggat cctgcagctg ctcaggaggg acaggatgag ggagcatctg caggtcaagg    300

gccgaagcct gaagctcata gccaggaaca gggtcaccca cagactgggt gtgagtgtga    360

agatggtcct gatgggcagg agatggaccc gccaaatcca gaggaggtga aaacgcctga    420

agaaggtgaa aagcaatcac agtgttaaaa gaagacacgt tgaaatgatg caggctgctc    480

ctatgttgga aatttgttca ttaaaattct cccaataaag ctttacagcc ttctgcaaag    540

aaaaaaaaaa aaa                                                       553


<210>  952
<211>  1475
<212>  DNA
<213>  Homo sapiens

<400>  952
aagagccgcg ggagcgcgga gcggccgctg ttcgcctgcg tcgctccggg agctgccgac     60

ggacggagcg cccccgcccc cgcccggccg cccgcccgcc gccgccatgc ccttctccaa    120

cagccacaac gcactgaagc tgcgcttccc ggccgaggac gagttccccg acctgagcgc    180

ccacaacaac cacatggcca aggtgctgac ccccgagctg tacgcggagc tgcgcgccaa    240

gagcacgccg agcggcttca cgctggacga cgtcatccag acaggcgtgg acaacccggg    300

ccacccgtac atcatgaccg tgggctgcgt ggcgggcgac gaggagtcct acgaagtgtt    360

caaggatctc ttcgacccca tcatcgagga ccggcacggc ggctacaagc ccagcgatga    420

gcacaagacc gacctcaacc ccgacaacct gcagggcggc gacgacctgg accccaacta    480

cgtgctgagc tcgcgggtgc gcacgggccg cagcatccgt ggcttctgcc tccccccgca    540

ctgcagccgc ggggagcgcc gcgccatcga gaagctcgcg gtggaagccc tgtccagcct    600

ggacggcgac ctggcgggcc gatactacgc gctcaagagc atgacggagg cggagcagca    660

gcagctcatc gacgaccact tcctcttcga caagcccgtg tcgcccctgc tgctggcctc    720

gggcatggcc cgcgactggc ccgacgcccg cggtatctgg cacaatgaca ataagacctt    780

cctggtgtgg gtcaacgagg aggaccacct gcgggtcatc tccatgcaga aggggggcaa    840

catgaaggag gtgttcaccc gcttctgcac cggcctcacc cagattgaaa ctctcttcaa    900

gtctaaggac tatgagttca tgtggaaccc tcacctgggc tacatcctca cctgcccatc    960

caacctgggc accgggctgc gggcaggtgt gcatatcaag ctgcccaacc tgggcaagca   1020

tgagaagttc tcggaggtgc ttaagcggct gcgacttcag aagcgaggca caggcggtgt   1080

ggacacggct gcggtgggcg gggtcttcga cgtctccaac gctgaccgcc tgggcttctc   1140

agaggtggag ctggtgcaga tggtggtgga cggagtgaag ctgctcatcg agatggagca   1200

gcggctggag cagggccagg ccatcgacga cctcatgcct gcccagaaat gaagcccggc   1260

ccacacccga caccagccct gctgcttcct aacttattgc ctgggcagtg cccaccatgc   1320

acccctgatg ttcgccgtct ggcgagccct tagccttgct gtagagactt ccgtcaccct   1380

tggtagagtt tatttttttg atggctaaga tactgctgat gctgaaataa actagggttt   1440

tggcctgcct gcgtctgaaa aaaaaaaaaa aaaaa                              1475


<210>  953
<211>  1506
<212>  DNA
<213>  Homo sapiens

<400>  953
ctgcctgggg agcccccccg ccccacatcc tgccccgcaa aaggcagctt caccaaagtg     60

gggtatttcc agcctttgta gctttcactt ccacatctac caagtgggcg gagtggcctt    120

ctgtggacga atcagattcc tctccagcac cgactttaag aggcgagccg gggggtcagg    180

gtcccagatg cacaggagga gaagcaggag ctgtcgggaa gatcagaagc cagtcatgga    240

tgaccagcgc gaccttatct ccaacaatga gcaactgccc atgctgggcc ggcgccctgg    300

ggccccggag agcaagtgca gccgcggagc cctgtacaca ggcttttcca tcctggtgac    360

tctgctcctc gctggccagg ccaccaccgc ctacttcctg taccagcagc agggccggct    420

ggacaaactg acagtcacct cccagaacct gcagctggag aacctgcgca tgaagcttcc    480

caagcctccc aagcctgtga gcaagatgcg catggccacc ccgctgctga tgcaggcgct    540

gcccatggga gccctgcccc aggggcccat gcagaatgcc accaagtatg gcaacatgac    600

agaggaccat gtgatgcacc tgctccagaa tgctgacccc ctgaaggtgt acccgccact    660

gaaggggagc ttcccggaga acctgagaca ccttaagaac accatggaga ccatagactg    720

gaaggtcttt gagagctgga tgcaccattg gctcctgttt gaaatgagca ggcactcctt    780

ggagcaaaag cccactgacg ctccaccgaa agagtcactg gaactggagg acccgtcttc    840

tgggctgggt gtgaccaagc aggatctggg cccagtcccc atgtgagagc agcagaggcg    900

gtcttcaaca tcctgccagc cccacacagc tacagctttc ttgctccctt cagcccccag    960

cccctccccc atctcccacc ctgtacctca tcccatgaga ccctggtgcc tggctctttc   1020

gtcacccttg gacaagacaa accaagtcgg aacagcagat aacaatgcag caaggccctg   1080

ctgcccaatc tccatctgtc aacaggggcg tgaggtccca ggaagtggcc aaaagctaga   1140

cagatccccg ttcctgacat cacagcagcc tccaacacaa ggctccaaga cctaggctca   1200

tggacgagat gggaaggcac agggagaagg gataacccta cacccagacc ccaggctgga   1260

catgctgact gtcctctccc ctccagcctt tggccttggc ttttctagcc tatttacctg   1320

caggctgagc cactctcttc cctttcccca gcatcactcc ccaaggaaga gccaatgttt   1380

tccacccata atcctttctg ccgaccccta gttccctctg ctcagccaag cttgttatca   1440

gctttcaggg ccatggttca cattagaata aaaggtagta attagaacaa aaaaaaaaaa   1500

aaaaaa                                                              1506


<210>  954
<211>  1691
<212>  DNA
<213>  Homo sapiens

<400>  954
tacccccatc cactcttctg gcagggctgg ggaccttggg gcaggtggtc tccctccaga     60

agagccctgt gttcagccag ccctgtcctc cagagcaagc cccacaggta gcaagcccca    120

caggtagcaa agtcagggag ggtaatggct tagccccagg ctcccaagct gggcagaaca    180

gggcagggag ctggagaggg tttggcagtg ggcccatgaa tccagcctgg gcaaggccct    240

gctgtgaggg acccctaggg acccctgggc ctgccaggga ggaagggctg cccagaaaag    300

gtactgactg atgcctcctc accatcttct gccttggctg gcacaggtcc caagtgcaga    360

gggggagctg gtcaggctgg tcagtcgggc gggggggcgg ggggcatgtt tctggcctgc    420

tgtcaccatg gaaatggcag tggctgcagg gtgtgtgtgc aagggaggag ggtgctgcca    480

cagagagccc agccaggacc accatgaaag ccaggagcac cgagggcctc tggttggctc    540

acaaacatgc ctggtgcacc aggcagaggg aacagccgag aaggtgagct ccctggggaa    600

ggactggcac aagttctgcc tcaagtgcga gcgctgcagc aagacgctga cgcccggggg    660

ccacgccgag catgacggga agccgttctg ccacaagccg tgctacgcca ccctgttcgg    720

acccaaaggc gtgaacatcg ggggcgcggg ctcctacatc tacgagaagc ccctggcgga    780

ggggccgcag gtcaccggcc ccatcgaggt ccccgcggcc cgagcagagg agcggaaggc    840

gagcggcccc ccgaaggggc ccagcagagc ctccagtgtc accactttca ccggggagcc    900

caacacgtgc ccgcgctgca gcaagaaggt gtacttcgct gagaaggtga cgtctctggg    960

caaggattgg caccggccct gcctgcgctg cgagcgctgc gggaagacac tgacccccgg   1020

cgggcacgcg gagcacgacg gccagcccta ctgccacaag ccctgctatg gaatcctctt   1080

cggacccaag ggagtgaaca ccggtgcggt gggcagctac atctatgacc gggaccccga   1140

aggcaaggtc cagccctagg ctacagcggc tctcatgatg tgggctcacc tgcgccccag   1200

accctgcagg ggcccccctg cttggctctg ctgggagagt gctcagccgc ccagtcctgc   1260

ctgcaagccc agggcgagta ttggaggagg ggcagccacg ggcagagcac catgcccatc   1320

cccgagtctc tggtgtgtct gccccctctg gcatcctctg ggcgtcccat gatcccttct   1380

gtgtctgcgt gtccgaatcc ccgtgtgacc ctgtcccagc attttcccgc cgaccctgcg   1440

tgtccccgtg gcgctgtccg ctctccctct cctgctgccc acccacctgc cagtgttatt   1500

tatgctccct tcgtgggtga tggccacgcc ctcaccatgt ccctggcaga gggcttccct   1560

ccgggatccc ctgcctggtg cccacactgc ctcgcaagcg ctcgccaccc tcacgtggct   1620

cacctgctgt tgagccttgt gctgtcaata aacggtttga ggattgcagg attgtcaaaa   1680

aaaaaaaaaa a                                                        1691


<210>  955
<211>  3198
<212>  DNA
<213>  Homo sapiens

<400>  955
acctcgattg ggggcggggc ggcaatctgg gtcttgtgcc tctggctcct cagggcattc     60

ccggcggctc cgggtttggc aacgaggacg ggggagtgcg actgcgtctc gggcagcatg    120

gccgagaagc ggcacacacg ggactccgaa gcccagcggc tccccgactc cttcaaggac    180

agccccagta agggccttgg accttgcgga tggattttgg tggcgttctc attcttattc    240

accgttataa ctttcccaat ctcaatatgg atgtgcataa agattataaa agagtatgaa    300

agagccatca tctttagatt gggtcgcatt ttacaaggag gagccaaagg acctggtttg    360

ttttttattc tgccatgcac tgacagcttc atcaaagtgg acatgagaac tatttcattt    420

gatattcctc ctcaggagat cctcacaaag gattcagtga caattagcgt ggatggtgtg    480

gtctattacc gcgttcagaa tgcaaccctg gctgtggcaa atatcaccaa cgctgactca    540

gcaacccgtc ttttggcaca aactactctg aggaatgttc tgggcaccaa gaatctttct    600

cagatcctct ctgacagaga agaaattgca cacaacatgc agtctactct ggatgatgcc    660

actgatgcct ggggaataaa ggtggagcgt gtggaaatta aggatgtgaa actacctgtg    720

cagctccaga gagctatggc tgcagaagca gaagcgtccc gcgaggcccg cgccaaggtt    780

attgcagccg aaggagaaat gaatgcatcc agggctctga aagaagcctc catggtcatc    840

actgaatctc ctgcagccct tcagctccga tacctgcaga cactgaccac cattgctgct    900

gagaaaaact caacaattgt cttccctctg cccatagata tgctgcaagg aatcataggg    960

gcaaaacaca gccatctagg ctagtgtaga gatgagcgct agccttccaa gcatgaagtc   1020

ggggaccaaa ttagccttta actcataaag agagggtagg gcttttcttt ttccatatgt   1080

caattgtggt gttcccagaa tgtatagcag ttataaaaat aggtgaaaga attgttagct   1140

tgtaaatact gagagattgg tgatttatat aaggtaatct gttagtctta aaatagttaa   1200

aagtttgtat ttttagatta ttatgtagta ggttagatcc ctcttgtttt gacttccact   1260

gactcattct gaacccccta agcacccagg ccagaggcaa gaacctgggc tgtaactgcc   1320

acctgacacc gctgactggc taaatgcttt gcagaaagtg atgaccttac accacaacca   1380

gcttctccag gtcatatgtg ccttacctcc agagagtctt tttttttttt tttctgagat   1440

ggagtttcac tcttgttgcc caggctggag tgcaatagca tgatctcggc tcactgcaac   1500

ctccgcctcc tgggttcaag agattctcct gcctcagcct ccccagtagc tgggattaca   1560

ggctcatgcc accatgccca gctaattttt gtattattat tattgttttt tagtagagac   1620

ggggtttcac catgttggcc aggctagtca cgaactccta acctcaggtg atccacccac   1680

ctctgcctcc caaagtgctg ggattacagg catgagctac cacacctggt ttggagagtc   1740

ttaattaagg aaatttccct aatgttcatt tattttctaa atccagaccg tgtttcagaa   1800

taatccttac ttgagagtag ccattttctt gcctgtactt gtcagaacta gaggaaatag   1860

ccaagactaa tgaaaaagat tactctaacc cttaaaagac ttttaaattc actactagag   1920

tggtcatttt aaaaatacat ccatgtttta acttatttga gccttcttta tgagtaaatg   1980

attcctcctt gttctgtctt tcaaaccagc taaatatttg tcacaaaagt gcttttttct   2040

cactgttgcc tattttcata tatcaggttt taaatagttt taatttttta ataaaatttt   2100

ctctacgttc tatatgcaat tgttatatat ctatttgaat agctgaagga ctaaaatact   2160

tttttaagag ataacttcag gaaaccatta tattttacta tctgcatgct gttaactgtg   2220

gtacactgtg aaatatgttg attacaaacc cattcattac atagtataag gaattcacag   2280

tatattgact atatagtgtc taatgatctt gggcagatac tgtcaaactt acaatatcta   2340

tatagatgta ggtcttttta aatttaccta gtcattcttc tatcatgtat attgatgctg   2400

aaagaggaac tggtcagctc ctctggacaa caaattctta gtctataata ttaggagaca   2460

tcttctgttt tgcaaatgtc tgtgaatctg agcaacctgg cattctgctt actggccaga   2520

aagctggcgg gtgacatttg taacatttcc tctttgagac tctgagttca cctagagaag   2580

tctaagcata acagctttct ttcccagcac gagcctttat agctctcttt agctcaacca   2640

ctctgtccat ccagccaatg gatgtccctt cccctgtacc ccaatttcaa gcttatttta   2700

ggaagccttg aactaccatg tatcctggct cctagctgag tttattagag gtatggagca   2760

gtgcaactta aactcaagtt gcacttacat tttgaatttt aaaatgatgg ttttatctgt   2820

tgtgtgaagt ggttcaccct tgaggaccag gagcctccat atcctgactg aaaacctttt   2880

ctgagactta gagtaacagt gcttttggtt ccttgagttc tcctgtctcc agataccaaa   2940

tgaccttgac ttttctgcct tgtgaattcg tagtccaatc agctgaaatt aaatcacttg   3000

ggagggacgc atagaaggag ctctaggaac acagtgccag tgcagaagtt tctccaggtg   3060

gcctcccttt ccaacaatgt acataataaa gtgtatgcac tttcactaat atttttgggg   3120

tgagagtctg tttcggcctg tattgaatgt ctgtggattt ccgttttcag aagtagtaca   3180

ttagatcctc cggttctg                                                 3198


<210>  956
<211>  8533
<212>  DNA
<213>  Homo sapiens

<400>  956
attcgcgtgg aggcgcgtcg cgcgcagcgg acgccgacag aatccccgag gcgcctggcg     60

cgggcgcggg cgcgaaggcg atccgggcgc caccccgcgg tcatcggtca ccggtcgctc    120

tcaggaacag cagcgcaacc tctgctccct gcctcgcctc ccgcgcgcct aggtgcctgc    180

gactttaatt aaagggccgt cccctcgccg aggctgcagc accgcccccc cggcttctcg    240

cgcctcaaaa tgagtagctc ccactctcgg gcgggccaga gcgcagcagg cgcggctccg    300

ggcggcggcg tcgacacgcg ggacgccgag atgccggcca ccgagaagga cctggcggag    360

gacgcgccgt ggaagaagat ccagcagaac actttcacgc gctggtgcaa cgagcacctg    420

aagtgcgtga gcaagcgcat cgccaacctg cagacggacc tgagcgacgg gctgcggctt    480

atcgcgctgt tggaggtgct cagccagaag aagatgcacc gcaagcacaa ccagcggccc    540

actttccgcc aaatgcagct tgagaacgtg tcggtggcgc tcgagttcct ggaccgcgag    600

agcatcaaac tggtgtccat cgacagcaag gccatcgtgg acgggaacct gaagctgatc    660

ctgggcctca tctggaccct gatcctgcac tactccatct ccatgcccat gtgggacgag    720

gaggaggatg aggaggccaa gaagcagacc cccaagcaga ggctcctggg ctggatccag    780

aacaagctgc cgcagctgcc catcaccaac ttcagccggg actggcagag cggccgggcc    840

ctgggcgccc tggtggacag ctgtgccccg ggcctgtgtc ctgactggga ctcttgggac    900

gccagcaagc ccgttaccaa tgcgcgagag gccatgcagc aggcggatga ctggctgggc    960

atcccccagg tgatcacccc cgaggagatt gtggacccca acgtggacga gcactctgtc   1020

atgacctacc tgtcccagtt ccccaaggcc aagctgaagc caggggctcc cttgcggccc   1080

aaactgaacc cgaagaaagc ccgtgcctac gggccaggca tcgagcccac aggcaacatg   1140

gtgaagaagc gggcagagtt cactgtggag accagaagtg ctggccaggg agaggtgctg   1200

gtgtacgtgg aggacccggc cggacaccag gaggaggcaa aagtgaccgc caataacgac   1260

aagaaccgca ccttctccgt ctggtacgtc cccgaggtga cggggactca taaggttact   1320

gtgctctttg ctggccagca catcgccaag agccccttcg aggtgtacgt ggataagtca   1380

cagggtgacg ccagcaaagt gacagcccaa ggtcccggcc tggagcccag tggcaacatc   1440

gccaacaaga ccacctactt tgagatcttt acggcaggag ctggcacggg cgaggtcgag   1500

gttgtgatcc aggaccccat gggacagaag ggcacggtag agcctcagct ggaggcccgg   1560

ggcgacagca cataccgctg cagctaccag cccaccatgg agggcgtcca caccgtgcac   1620

gtcacgtttg ccggcgtgcc catccctcgc agcccctaca ctgtcactgt tggccaagcc   1680

tgtaacccga gtgcctgccg ggcggttggc cggggcctcc agcccaaggg tgtgcgggtg   1740

aaggagacag ctgacttcaa ggtgtacaca aagggcgctg gcagtgggga gctgaaggtc   1800

accgtgaagg gccccaaggg agaggagcgc gtgaagcaga aggacctggg ggatggcgtg   1860

tatggcttcg agtattaccc catggtccct ggaacctata tcgtcaccat cacgtggggt   1920

ggtcagaaca tcgggcgcag tcccttcgaa gtgaaggtgg gcaccgagtg tggcaatcag   1980

aaggtacggg cctggggccc tgggctggag ggcggcgtcg ttggcaagtc agcagacttt   2040

gtggtggagg ctatcgggga cgacgtgggc acgctgggct tctcggtgga agggccatcg   2100

caggctaaga tcgaatgtga cgacaagggc gacggctcct gtgatgtgcg ctactggccg   2160

caggaggctg gcgagtatgc cgttcacgtg ctgtgcaaca gcgaagacat ccgcctcagc   2220

cccttcatgg ctgacatccg tgacgcgccc caggacttcc acccagacag ggtgaaggca   2280

cgtgggcctg gattggagaa gacaggtgtg gccgtcaaca agccagcaga gttcacagtg   2340

gatgccaagc acggtggcaa ggccccactt cgggtccaag tccaggacaa tgaaggctgc   2400

cctgtggagg cgttggtcaa ggacaacggc aatggcactt acagctgctc ctacgtgccc   2460

aggaagccgg tgaagcacac agccatggtg tcctggggag gcgtcagcat ccccaacagc   2520

cccttcaggg tgaatgtggg agctggcagc caccccaaca aggtcaaagt atacggcccc   2580

ggagtagcca agacagggct caaggcccac gagcccacct acttcactgt ggactgcgcc   2640

gaggctggcc agggggacgt cagcatcggc atcaagtgtg cccctggagt ggtaggcccc   2700

gccgaagctg acatcgactt cgacatcatc cgcaatgaca atgacacctt cacggtcaag   2760

tacacgcccc ggggggctgg cagctacacc attatggtcc tctttgctga ccaggccacg   2820

cccaccagcc ccatccgagt caaggtggag ccctctcatg acgccagtaa ggtgaaggcc   2880

gagggccctg gcctcagtcg cactggtgtc gagcttggca agcccaccca cttcacagta   2940

aatgccaaag ctgctggcaa aggcaagctg gacgtccagt tctcaggact caccaagggg   3000

gatgcagtgc gagatgtgga catcatcgac caccatgaca acacctacac agtcaagtac   3060

acgcctgtcc agcagggtcc agtaggcgtc aatgtcactt atggagggga tcccatccct   3120

aagagccctt tctcagtggc agtatctcca agcctggacc tcagcaagat caaggtgtct   3180

ggcctgggag agaaggtgga cgttggcaaa gaccaggagt tcacagtcaa atcaaagggt   3240

gctggtggtc aaggcaaagt ggcatccaag attgtgggcc cctcgggtgc agcggtgccc   3300

tgcaaggtgg agccaggcct gggggctgac aacagtgtgg tgcgcttcct gccccgtgag   3360

gaagggccct atgaggtgga ggtgacctat gacggcgtgc ccgtgcctgg cagccccttt   3420

cctctggaag ctgtggcccc caccaagcct agcaaggtga aggcgtttgg gccggggctg   3480

cagggaggca gtgcgggctc ccccgcccgc ttcaccatcg acaccaaggg cgccggcaca   3540

ggtggcctgg gcctgacggt ggagggcccc tgtgaggcgc agctcgagtg cttggacaat   3600

ggggatggca catgttccgt gtcctacgtg cccaccgagc ccggggacta caacatcaac   3660

atcctcttcg ctgacaccca catccctggc tccccattca aggcccacgt ggttccctgc   3720

tttgacgcat ccaaagtcaa gtgctcaggc cccgggctgg agcgggccac cgctggggag   3780

gtgggccaat tccaagtgga ctgctcgagc gcgggcagcg cggagctgac cattgagatc   3840

tgctcggagg cggggcttcc ggccgaggtg tacatccagg accacggtga tggcacgcac   3900

accattacct acattcccct ctgccccggg gcctacaccg tcaccatcaa gtacggcggc   3960

cagcccgtgc ccaacttccc cagcaagctg caggtggaac ctgcggtgga cacttccggt   4020

gtccagtgct atgggcctgg tattgagggc cagggtgtct tccgtgaggc caccactgag   4080

ttcagtgtgg acgcccgggc tctgacacag accggagggc cgcacgtcaa ggcccgtgtg   4140

gccaacccct caggcaacct gacggagacc tacgttcagg accgtggcga tggcatgtac   4200

aaagtggagt acacgcctta cgaggaggga ctgcactccg tggacgtgac ctatgacggc   4260

agtcccgtgc ccagcagccc cttccaggtg cccgtgaccg agggctgcga cccctcccgg   4320

gtgcgtgtcc acgggccagg catccaaagt ggcaccacca acaagcccaa caagttcact   4380

gtggagacca ggggagctgg cacgggcggc ctgggcctgg ctgtagaggg cccctccgag   4440

gccaagatgt cctgcatgga taacaaggac ggcagctgct cggtcgagta catcccttat   4500

gaggctggca cctacagcct caacgtcacc tatggtggcc atcaagtgcc aggcagtcct   4560

ttcaaggtcc ctgtgcatga tgtgacagat gcgtccaagg tcaagtgctc tgggcccggc   4620

ctgagcccag gcatggttcg tgccaacctc cctcagtcct tccaggtgga cacaagcaag   4680

gctggtgtgg ccccattgca ggtcaaagtg caagggccca aaggcctggt ggagccagtg   4740

gacgtggtag acaacgctga tggcacccag accgtcaatt atgtgcccag ccgagaaggg   4800

ccctacagca tctcagtact gtatggagat gaagaggtac cccggagccc cttcaaggtc   4860

aaggtgctgc ctactcatga tgccagcaag gtgaaggcca gtggccccgg gctcaacacc   4920

actggcgtgc ctgccagcct gcccgtggag ttcaccatcg atgcaaagga cgccggggag   4980

ggcctgctgg ctgtccagat cacggatccc gaaggcaagc cgaagaagac acacatccaa   5040

gacaaccatg acggcacgta tacagtggcc tacgtgccag acgtgacagg tcgctacacc   5100

atcctcatca agtacggtgg tgacgagatc cccttctccc cgtaccgcgt gcgtgccgtg   5160

cccaccgggg acgccagcaa gtgcactgtc acaggtgctg gcatcggccc caccattcag   5220

attggggagg agacggtgat cactgtggac actaaggcgg caggcaaagg caaagtgacg   5280

tgcaccgtgt gcacgcctga tggctcagag gtggatgtgg acgtggtgga gaatgaggac   5340

ggcactttcg acatcttcta cacggccccc cagccgggca aatacgtcat ctgtgtgcgc   5400

tttggtggcg agcacgtgcc caacagcccc ttccaagtga cggctctggc tggggaccag   5460

ccctcggtgc agccccctct acggtctcag cagctggccc cacagtacac ctacgcccag   5520

ggcggccagc agacttgggc cccggagagg cccctggtgg gtgtcaatgg gctggatgtg   5580

accagcctga ggccctttga ccttgtcatc cccttcacca tcaagaaggg cgagatcaca   5640

ggggaggttc ggatgccctc aggcaaggtg gcgcagccca ccatcactga caacaaagac   5700

ggcaccgtga ccgtgcggta tgcacccagc gaggctggcc tgcacgagat ggacatccgc   5760

tatgacaaca tgcacatccc aggaagcccc ttgcagttct atgtggatta cgtcaactgt   5820

ggccatgtca ctgcctatgg gcctggcctc acccatggag tagtgaacaa gcctgccacc   5880

ttcaccgtca acaccaagga tgcaggagag gggggcctgt ctctggccat tgagggcccg   5940

tccaaagcag aaatcagctg cactgacaac caggatggga catgcagcgt gtcctacctg   6000

cctgtgctgc cgggggacta cagcattcta gtcaagtaca atgaacagca cgtcccaggc   6060

agccccttca ctgctcgggt cacaggtgac gactccatgc gtatgtccca cctaaaggtc   6120

ggctctgctg ccgacatccc catcaacatc tcagagacgg atctcagcct gctgacggcc   6180

actgtggtcc cgccctcggg ccgggaggag ccctgtttgc tgaagcggct gcgtaatggc   6240

cacgtgggga tttcattcgt gcccaaggag acgggggagc acctggtgca tgtgaagaaa   6300

aatggccagc acgtggccag cagccccatc ccggtggtga tcagccagtc ggaaattggg   6360

gatgccagtc gtgttcgggt ctctggtcag ggccttcacg aaggccacac ctttgagcct   6420

gcagagttta tcattgatac ccgcgatgca ggctatggtg ggctcagcct gtccattgag   6480

ggccccagca aggtggacat caacacagag gacctggagg acgggacgtg cagggtcacc   6540

tactgcccca cagagccagg caactacatc atcaacatca agtttgccga ccagcacgtg   6600

cctggcagcc ccttctctgt gaaggtgaca ggcgagggcc gggtgaaaga gagcatcacc   6660

cgcaggcgtc gggctccttc agtggccaac gttggtagtc attgtgacct cagcctgaaa   6720

atccctgaaa ttagcatcca ggatatgaca gcccaggtga ccagcccatc gggcaagacc   6780

catgaggccg agatcgtgga aggggagaac cacacctact gcatccgctt tgttcccgct   6840

gagatgggca cacacacagt cagcgtgaag tacaagggcc agcacgtgcc tgggagcccc   6900

ttccagttca ccgtggggcc cctaggggaa gggggagccc acaaggtccg agctgggggc   6960

cctggcctgg agagagctga agctggagtg ccagccgaat tcagtatctg gacccgggaa   7020

gctggtgctg gaggcctggc cattgctgtc gagggcccca gcaaggctga gatctctttt   7080

gaggaccgca aggacggctc ctgtggtgtg gcttatgtgg tccaggagcc aggtgactac   7140

gaagtctcag tcaagttcaa cgaggaacac attcccgaca gccccttcgt ggtgcctgtg   7200

gcttctccgt ctggcgacgc ccgccgcctc actgtttcta gccttcagga gtcagggcta   7260

aaggtcaacc agccagcctc ttttgcagtc agcctgaacg gggccaaggg ggcgatcgat   7320

gccaaggtgc acagcccctc aggagccctg gaggagtgct atgtcacaga aattgaccaa   7380

gataagtatg ctgtgcgctt catccctcgg gagaatggcg tttacctgat tgacgtcaag   7440

ttcaacggca cccacatccc tggaagcccc ttcaagatcc gagttgggga gcctgggcat   7500

ggaggggacc caggcttggt gtctgcttac ggagcaggtc tggaaggcgg tgtcacaggg   7560

aacccagctg agttcgtcgt gaacacgagc aatgcgggag ctggtgccct gtcggtgacc   7620

attgacggcc cctccaaggt gaagatggat tgccaggagt gccctgaggg ctaccgcgtc   7680

acctataccc ccatggcacc tggcagctac ctcatctcca tcaagtacgg cggcccctac   7740

cacattgggg gcagcccctt caaggccaaa gtcacaggcc cccgtctcgt cagcaaccac   7800

agcctccacg agacatcatc agtgtttgta gactctctga ccaaggccac ctgtgccccc   7860

cagcatgggg ccccgggtcc tgggcctgct gacgccagca aggtggtggc caagggcctg   7920

gggctgagca aggcctacgt aggccagaag agcagcttca cagtagactg cagcaaagca   7980

ggcaacaaca tgctgctggt gggggttcat ggcccaagga ccccctgcga ggagatcctg   8040

gtgaagcacg tgggcagccg gctctacagc gtgtcctacc tgctcaagga caagggggag   8100

tacacactgg tggtcaaatg gggggacgag cacatcccag gcagccccta ccgcgttgtg   8160

gtgccctgag tctggggccc gtgccagccg gcagccccca agcctgcccc gctacccaag   8220

cagccccgcc ctcttcccct caaccccggc ccaggccgcc ctggccgccc gcctgtcact   8280

gcagccgccc ctgccctgtg ccgtgctgcg ctcacctgcc tccccagcca gccgctgacc   8340

tctcggcttt cacttgggca gagggagcca tttggtggcg ctgcttgtct tctttggttc   8400

tgggaggggt gagggatggg ggtcctgtac acaaccaccc actagttctc ttctccagcc   8460

aagaggaata aagttttgct tccattaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   8520

aaaaaaaaaa aaa                                                      8533


<210>  957
<211>  2501
<212>  DNA
<213>  Homo sapiens

<400>  957
gtagtttccc gcccttgggg gcgcggggac aaattccttg acccgaggag gatagggatg     60

tggccttcgg tctttcctcg cagctccggg gcaagctagg agtgggatgg aagtcgagag    120

tcgatcccgg agcccggccg cggggagagg ttctcggcag agaagacaaa gcccgcagca    180

gcgatggggg gagagctggg ctctgcgtgt tgtgggggcc aggaaagggt gccaggctgg    240

ggctggaacc ccctggcaaa ggatggggtc ccctcatccc taaacagcaa gccatctccc    300

ctcgcccgcc ccccgccccc ccagtctcgg agatctcaga ggcaccgact gggagacttg    360

atgtaattgt cttcacaatt ctgtgaagat ggacttggtg tctctgcttc acatgaaggg    420

acctgaggtt cagagaggct aagtaacttt cctaggtcac agagctgtgt tcgcgggagc    480

gccgcaccta caccagccaa cccagatccc gaggtccgac agcgcccggc ccagatcccc    540

acgcctgcca ggagcaagcc gagagccagc cggccggcgc actccgactc cgagcagtct    600

ctgtccttcg acccgagccc cgcgcccttt ccgggacccc tgccccgcgg gcagcgctgc    660

caacctgccg gccatggaga ccccgtccca gcggcgcgcc acccgcagcg gggcgcaggc    720

cagctccact ccgctgtcgc ccacccgcat cacccggctg caggagaagg aggacctgca    780

ggagctcaat gatcgcttgg cggtctacat cgaccgtgtg cgctcgctgg aaacggagaa    840

cgcagggctg cgccttcgca tcaccgagtc tgaagaggtg gtcagccgcg aggtgtccgg    900

catcaaggcc gcctacgagg ccgagctcgg ggatgcccgc aagacccttg actcagtagc    960

caaggagcgc gcccgcctgc agctggagct gagcaaagtg cgtgaggagt ttaaggagct   1020

gaaagcgcgc aataccaaga aggagggtga cctgatagct gctcaggctc ggctgaagga   1080

cctggaggct ctgctgaact ccaaggaggc cgcactgagc actgctctca gtgagaagcg   1140

cacgctggag ggcgagctgc atgatctgcg gggccaggtg gccaagcttg aggcagccct   1200

aggtgaggcc aagaagcaac ttcaggatga gatgctgcgg cgggtggatg ctgagaacag   1260

gctgcagacc atgaaggagg aactggactt ccagaagaac atctacagtg aggagctgcg   1320

tgagaccaag cgccgtcatg agacccgact ggtggagatt gacaatggga agcagcgtga   1380

gtttgagagc cggctggcgg atgcgctgca ggaactgcgg gcccagcatg aggaccaggt   1440

ggagcagtat aagaaggagc tggagaagac ttattctgcc aagctggaca atgccaggca   1500

gtctgctgag aggaacagca acctggtggg ggctgcccac gaggagctgc agcagtcgcg   1560

catccgcatc gacagcctct ctgcccagct cagccagctc cagaagcagc tggcagccaa   1620

ggaggcgaag cttcgagacc tggaggactc actggcccgt gagcgggaca ccagccggcg   1680

gctgctggcg gaaaaggagc gggagatggc cgagatgcgg gcaaggatgc agcagcagct   1740

ggacgagtac caggagcttc tggacatcaa gctggccctg gacatggaga tccacgccta   1800

ccgcaagctc ttggagggcg aggaggagag gctacgcctg tcccccagcc ctacctcgca   1860

gcgcagccgt ggccgtgctt cctctcactc atcccagaca cagggtgggg gcagcgtcac   1920

caaaaagcgc aaactggagt ccactgagag ccgcagcagc ttctcacagc acgcacgcac   1980

tagcgggcgc gtggccgtgg aggaggtgga tgaggagggc aagtttgtcc ggctgcgcaa   2040

caagtccaat gaggaccagt ccatgggcaa ttggcagatc aagcgccaga atggagatga   2100

tcccttgctg acttaccggt tcccaccaaa gttcaccctg aaggctgggc aggtggtgac   2160

gatctgggct gcaggagctg gggccaccca cagcccccct accgacctgg tgtggaaggc   2220

acagaacacc tggggctgcg ggaacagcct gcgtacggct ctcatcaact ccactgggga   2280

agaagtggcc atgcgcaagc tggtgcgctc agtgactgtg gttgaggacg acgaggatga   2340

ggatggagat gacctgctcc atcaccacca cgtgagtggt agccgccgct gaggccgagc   2400

ctgcactggg gccacccagc caggcctggg ggcagcctct ccccagcctc cccgtgccaa   2460

aaatcttttc attaaagaat gttttggaac tttaaaaaaa a                       2501


<210>  958
<211>  1853
<212>  DNA
<213>  Homo sapiens

<400>  958
cgctccacct ctcaagcagc cagcgcctgc ctgaatctgt tctgccccct ccccacccat     60

ttcaccacca ccatgacacc gggcacccag tctcctttct tcctgctgct gctcctcaca    120

gtgcttacag ctaccacagc ccctaaaccc gcaacagttg ttacgggttc tggtcatgca    180

agctctaccc caggtggaga aaaggagact tcggctaccc agagaagttc agtgcccagc    240

tctactgaga agaatgctgt gagtatgacc agcagcgtac tctccagcca cagccccggt    300

tcaggctcct ccaccactca gggacaggat gtcactctgg ccccggccac ggaaccagct    360

tcaggttcag ctgccacctg gggacaggat gtcacctcgg tcccagtcac caggccagcc    420

ctgggctcca ccaccccgcc agcccacgat gtcacctcag ccccggacaa caagccagcc    480

ccgggctcca ccgccccccc agcccacggt gtcacctcgg ccccggacac caggccggcc    540

ccgggctcca ccgccccccc agcccatggt gtcacctcgg ccccggacaa caggcccgcc    600

ttgggctcca ccgcccctcc agtccacaat gtcacctcgg cctcaggctc tgcatcaggc    660

tcagcttcta ctctggtgca caacggcacc tctgccaggg ctaccacaac cccagccagc    720

aagagcactc cattctcaat tcccagccac cactctgata ctcctaccac ccttgccagc    780

catagcacca agactgatgc cagtagcact caccatagca cggtacctcc tctcacctcc    840

tccaatcaca gcacttctcc ccagttgtct actggggtct ctttcttttt cctgtctttt    900

cacatttcaa acctccagtt taattcctct ctggaagatc ccagcaccga ctactaccaa    960

gagctgcaga gagacatttc tgaaatgttt ttgcagattt ataaacaagg gggttttctg   1020

ggcctctcca atattaagtt caggccagga tctgtggtgg tacaattgac tctggccttc   1080

cgagaaggta ccatcaatgt ccacgacgtg gagacacagt tcaatcagta taaaacggaa   1140

gcagcctctc gatataacct gacgatctca gacgtcagcg tgagtgatgt gccatttcct   1200

ttctctgccc agtctggggc tggggtgcca ggctggggca tcgcgctgct ggtgctggtc   1260

tgtgttctgg ttgcgctggc cattgtctat ctcattgcct tggctgtctg tcagtgccgc   1320

cgaaagaact acgggcagct ggacatcttt ccagcccggg atacctacca tcctatgagc   1380

gagtacccca cctaccacac ccatgggcgc tatgtgcccc ctagcagtac cgatcgtagc   1440

ccctatgaga aggtttctgc aggtaatggt ggcagcagcc tctcttacac aaacccagca   1500

gtggcagcca cttctgccaa cttgtagggg cacgtcgccc gctgagctga gtggccagcc   1560

agtgccattc cactccactc aggttcttca gggccagagc ccctgcaccc tgtttgggct   1620

ggtgagctgg gagttcaggt gggctgctca cagcctcctt cagaggcccc accaatttct   1680

cggacacttc tcagtgtgtg gaagctcatg tgggcccctg agggctcatg cctgggaagt   1740

gttgtggtgg gggctcccag gaggactggc ccagagagcc ctgagatagc ggggatcctg   1800

aactggactg aataaaacgt ggtctcccac tgcgccaaaa aaaaaaaaaa aaa          1853


<210>  959
<211>  2439
<212>  DNA
<213>  Homo sapiens

<400>  959
gagagcagcg gccgggaagg ggcggtgcgg gaggcggggt gtggggcggt agtgtgggcc     60

ctgttcctgc ccgcgcggtg ttccgcattc tgcaagcctc cggagcgcac gtcggcagtc    120

ggctccctcg ttgaccgaat caccgacctc tctccccagc tgtatttcca aaatgtcgct    180

ttctaacaag ctgacgctgg acaagctgga cgttaaaggg aagcgggtcg ttatgagagt    240

cgacttcaat gttcctatga agaacaacca gataacaaac aaccagagga ttaaggctgc    300

tgtcccaagc atcaaattct gcttggacaa tggagccaag tcggtagtcc ttatgagcca    360

cctaggccgg cctgatggtg tgcccatgcc tgacaagtac tccttagagc cagttgctgt    420

agaactcaaa tctctgctgg gcaaggatgt tctgttcttg aaggactgtg taggcccaga    480

agtggagaaa gcctgtgcca acccagctgc tgggtctgtc atcctgctgg agaacctccg    540

ctttcatgtg gaggaagaag ggaagggaaa agatgcttct gggaacaagg ttaaagccga    600

gccagccaaa atagaagctt tccgagcttc actttccaag ctaggggatg tctatgtcaa    660

tgatgctttt ggcactgctc acagagccca cagctccatg gtaggagtca atctgccaca    720

gaaggctggt gggtttttga tgaagaagga gctgaactac tttgcaaagg ccttggagag    780

cccagagcga cccttcctgg ccatcctggg cggagctaaa gttgcagaca agatccagct    840

catcaataat atgctggaca aagtcaatga gatgattatt ggtggtggaa tggcttttac    900

cttccttaag gtgctcaaca acatggagat tggcacttct ctgtttgatg aagagggagc    960

caagattgtc aaagacctaa tgtccaaagc tgagaagaat ggtgtgaaga ttaccttgcc   1020

tgttgacttt gtcactgctg acaagtttga tgagaatgcc aagactggcc aagccactgt   1080

ggcttctggc atacctgctg gctggatggg cttggactgt ggtcctgaaa gcagcaagaa   1140

gtatgctgag gctgtcactc gggctaagca gattgtgtgg aatggtcctg tgggggtatt   1200

tgaatgggaa gcttttgccc ggggaaccaa agctctcatg gatgaggtgg tgaaagccac   1260

ttctaggggc tgcatcacca tcataggtgg tggagacact gccacttgct gtgccaaatg   1320

gaacacggag gataaagtca gccatgtgag cactgggggt ggtgccagtt tggagctcct   1380

ggaaggtaaa gtccttcctg gggtggatgc tctcagcaat atttagtact ttcctgcctt   1440

ttagttcctg tgcacagccc ctaagtcaac ttagcatttt ctgcatctcc acttggcatt   1500

agctaaaacc ttccatgtca agattcagct agtggccaag agatgcagtg ccaggaaccc   1560

ttaaacagtt gcacagcatc tcagctcatc ttcactgcac cctggatttg catacattct   1620

tcaagatccc atttgaattt tttagtgact aaaccattgt gcattctaga gtgcatatat   1680

ttatattttg cctgttaaaa agaaagtgag cagtgttagc ttagttctct tttgatgtag   1740

gttattatga ttagctttgt cactgtttca ctactcagca tggaaacaag atgaaattcc   1800

atttgtaggt agtgagacaa aattgatgat ccattaagta aacaataaaa gtgtccattg   1860

aaaccgtgat tttttttttt ttcctgtcat actttgttag gaagggtgag aatagaatct   1920

tgaggaacgg atcagatgtc tatattgctg aatgcaagaa gtggggcagc agcagtggag   1980

agatgggaca attagataaa tgtccattct ttatcaaggg cctactttat ggcagacatt   2040

gtgctagtgc ttttattcta acttttattt ttatcagtta cacatgatca taatttaaaa   2100

agtcaaggct tataacaaaa aagccccagc ccattcctcc cattcaagat tcccactccc   2160

cagaggtgac cactttcaac tcttgagttt ttcaggtata tacctccatg tttctaagta   2220

atatgcttat attgttcact tctttttttt ttatttttta aagaaatcta tttcatacca   2280

tggaggaagg ctctgttcca catatatttc cacttcttca ttctctcggt atagttttgt   2340

cacaattata gattagatca aaagtctaca taactaatac agctgagcta tgtagtatgc   2400

tatgattaaa tttacttatg taaaaaaaaa aaaaaaaaa                          2439


<210>  960
<211>  3538
<212>  DNA
<213>  Homo sapiens

<400>  960
gaatcattaa cttaatttga ctatctggtt tgtggatgcg tttactctca tgtaagtcaa     60

caacatcctg ggattgggac ccactttctg ggcactgctg gccagtccca aaatggaaca    120

taaggaagtg gttcttctac ttcttttatt tctgaaatca ggtcaaggag agcctctgga    180

tgactatgtg aatacccagg gggcttcact gttcagtgtc actaagaagc agctgggagc    240

aggaagtata gaagaatgtg cagcaaaatg tgaggaggac gaagaattca cctgcagggc    300

attccaatat cacagtaaag agcaacaatg tgtgataatg gctgaaaaca ggaagtcctc    360

cataatcatt aggatgagag atgtagtttt atttgaaaag aaagtgtatc tctcagagtg    420

caagactggg aatggaaaga actacagagg gacgatgtcc aaaacaaaaa atggcatcac    480

ctgtcaaaaa tggagttcca cttctcccca cagacctaga ttctcacctg ctacacaccc    540

ctcagaggga ctggaggaga actactgcag gaatccagac aacgatccgc aggggccctg    600

gtgctatact actgatccag aaaagagata tgactactgc gacattcttg agtgtgaaga    660

ggaatgtatg cattgcagtg gagaaaacta tgacggcaaa atttccaaga ccatgtctgg    720

actggaatgc caggcctggg actctcagag cccacacgct catggataca ttccttccaa    780

atttccaaac aagaacctga agaagaatta ctgtcgtaac cccgataggg agctgcggcc    840

ttggtgtttc accaccgacc ccaacaagcg ctgggaactt tgtgacatcc cccgctgcac    900

aacacctcca ccatcttctg gtcccaccta ccagtgtctg aagggaacag gtgaaaacta    960

tcgcgggaat gtggctgtta ccgtgtccgg gcacacctgt cagcactgga gtgcacagac   1020

ccctcacaca cataacagga caccagaaaa cttcccctgc aaaaatttgg atgaaaacta   1080

ctgccgcaat cctgacggaa aaagggcccc atggtgccat acaaccaaca gccaagtgcg   1140

gtgggagtac tgtaagatac cgtcctgtga ctcctcccca gtatccacgg aacaattggc   1200

tcccacagca ccacctgagc taacccctgt ggtccaggac tgctaccatg gtgatggaca   1260

gagctaccga ggcacatcct ccaccaccac cacaggaaag aagtgtcagt cttggtcatc   1320

tatgacacca caccggcacc agaagacccc agaaaactac ccaaatgctg gcctgacaat   1380

gaactactgc aggaatccag atgccgataa aggcccctgg tgttttacca cagaccccag   1440

cgtcaggtgg gagtactgca acctgaaaaa atgctcagga acagaagcga gtgttgtagc   1500

acctccgcct gttgtcctgc ttccagatgt agagactcct tccgaagaag actgtatgtt   1560

tgggaatggg aaaggatacc gaggcaagag ggcgaccact gttactggga cgccatgcca   1620

ggactgggct gcccaggagc cccatagaca cagcattttc actccagaga caaatccacg   1680

ggcgggtctg gaaaaaaatt actgccgtaa ccctgatggt gatgtaggtg gtccctggtg   1740

ctacacgaca aatccaagaa aactttacga ctactgtgat gtccctcagt gtgcggcccc   1800

ttcatttgat tgtgggaagc ctcaagtgga gccgaagaaa tgtcctggaa gggttgtagg   1860

ggggtgtgtg gcccacccac attcctggcc ctggcaagtc agtcttagaa caaggtttgg   1920

aatgcacttc tgtggaggca ccttgatatc cccagagtgg gtgttgactg ctgcccactg   1980

cttggagaag tccccaaggc cttcatccta caaggtcatc ctgggtgcac accaagaagt   2040

gaatctcgaa ccgcatgttc aggaaataga agtgtctagg ctgttcttgg agcccacacg   2100

aaaagatatt gccttgctaa agctaagcag tcctgccgtc atcactgaca aagtaatccc   2160

agcttgtctg ccatccccaa attatgtggt cgctgaccgg accgaatgtt tcatcactgg   2220

ctggggagaa acccaaggta cttttggagc tggccttctc aaggaagccc agctccctgt   2280

gattgagaat aaagtgtgca atcgctatga gtttctgaat ggaagagtcc aatccaccga   2340

actctgtgct gggcatttgg ccggaggcac tgacagttgc cagggtgaca gtggaggtcc   2400

tctggtttgc ttcgagaagg acaaatacat tttacaagga gtcacttctt ggggtcttgg   2460

ctgtgcacgc cccaataagc ctggtgtcta tgttcgtgtt tcaaggtttg ttacttggat   2520

tgagggagtg atgagaaata attaattgga cgggagacag agtgacgcac tgactcacct   2580

agaggctgga acgtgggtag ggatttagca tgctggaaat aactggcagt aatcaaacga   2640

agacactgtc cccagctacc agctacgcca aacctcggca ttttttgtgt tattttctga   2700

ctgctggatt ctgtagtaag gtgacatagc tatgacattt gttaaaaata aactctgtac   2760

ttaactttga tttgagtaaa ttttggtttt ggtcttcaac attttcatgc tctttgttca   2820

ccccaccaat ttttaaatgg gcagatgggg ggatttagct gcttttgata aggaacagct   2880

gcacaaagga ctgagcaggc tgcaaggtca cagaggggag agccaagaag ttgtccacgc   2940

atttacctca tcagctaacg agggcttgac atgcattttt actgtcttta ttcctgacac   3000

tgagatgaat gttttcaaag ctgcaacatg tatggggagt catgcaaacc gattctgtta   3060

ttgggaatga aatctgtcac cgactgcttg acttgagccc aggggacacg gagcagagag   3120

ctgtatatga tggagtgaac cggtccatgg atgtgtaaca caagaccaac tgagagtctg   3180

aatgttattc tggggcacac gtgagtctag gattggtgcc aagagcatgt aaatgaacaa   3240

caagcaaata ttgaaggtgg accacttatt tcccattgct aattgcctgc ccggttttga   3300

aacagtctgc agtacacacg gtcacaggag aatgacctgt gggagagata catgtttaga   3360

aggaagagaa aggacaaagg cacacgtttt accatttaaa atattgttac caaacaaaaa   3420

tatccattca aaatacaatt taacaatgca acagtcatct tacagcagag aaatgcagag   3480

aaaagcaaaa ctgcaagtga ctgtgaataa agggtgaatg tagtctcaaa tcctcaaa     3538


<210>  961
<211>  3336
<212>  DNA
<213>  Homo sapiens

<400>  961
agcgtctggc cgatttgggg acgcgggcag tcgcttccgg ccccggctcc cgcacattct     60

tgaggattgg gccggggatg ggaggaatgg ggacgcctgg ggacttgcac gccgcgtgcc    120

cctccaccac ccgccgggac gccctctgcc tcggtcccga gttcgagttc gacctccgcc    180

actcagctgg gtgtcctggg gaccttggtt tcttcccttt agatccggac actgaagcag    240

gcggtagcgg gtgtcttcct acctggctac cccttcggcg cctagcgcga ggcaggctgg    300

aggtcacagc agatctggca gagcggcggc gcatccgctc agccatccgg gaactgcagc    360

ggcaggagct ggagcgcgag gaggaggccc tggcatccaa gcgtttccgt gccgagcggc    420

aggacaacaa ggagaactgg ctgcactctc agcagcggga agctgagcag cgggctgccc    480

tggcacggct ggcagggcag ctggagtcca tgaacgatgt ggaggaattg actgcactgt    540

tgcgaagcgc tggtgagtat gaggagcgca agctgatccg agctgccatc cgccgtgtac    600

gggctcagga gattgaggct gccaccttgg ctgggaggtt gtacagcggg cgtcccaaca    660

gtggctcaag agaggacagc aaggggctag cggcacacag gctggaacag tgtgaggtgc    720

cagagcgaga ggaacaggaa cagcaggcag aggtttcaaa gccaaccccc acccctgaag    780

gcaccagcca ggatgtgacc acagtgacac tcctgctgcg agccccacct gggagcacat    840

ccagctcacc tgcctcaccc agcagttcac ccacccctgc ctctcctgag cctccattgg    900

agcctgccga ggcccagtgc cttacagctg aggttccagg cagcccagag ccacccccca    960

gcccacccaa gaccaccagc cctgagcctc aggagtctcc aacgctcccc agcactgagg   1020

gccaggtggt caacaagctt ctgtctggcc ccaaagagac ccctgctgcc cagagcccca   1080

ccagaggccc ctctgacacc aagagagcag acgtggctgg accccgaccc tgccaacgct   1140

ccctgtcggt gctcagcccc cgccaaccag cccagaaccg agagtccacc ccccttgcca   1200

gcggaccttc ctcattccag cgggctggct ctgtgcggga tcgtgtccac aagttcacat   1260

ctgattctcc tatggctgct aggctccagg atggcacacc ccaggctgcc ctaagtcccc   1320

tgacccccgc aaggctcctg ggcccctccc tcaccagcac cacccctgcc tcctcctcca   1380

gcggctcctc ctctcggggc cccagtgata cctcctcccg gttcagcaag gagcaacgag   1440

gagtagccca gcccctggcc cagcttcgaa gctgccccca ggaggagggc cccagggggc   1500

ggggcttggc tgctaggccc cttgaaaaca gagcaggggg gcctgtggca cgttcagagg   1560

agcctggtgc cccgctgccc gtggccgtcg gcactgccga gccagggggc agtatgaaga   1620

ccacattcac catcgagatc aaggacggcc gtggccaggc ctccacaggc cgggtgctgc   1680

tgcccacagg caaccagagg gcagaactga cactggggct gcgggcgccc ccgaccctac   1740

tcagcaccag tagtgggggc aagagcacca tcacccgtgt caacagccct gggaccctgg   1800

ctcggctggg cagtgtcact catgtcacca gcttcagcca tgcccccccc agtagccgag   1860

gaggctgcag catcaagatg gaagcagagc cagcagagcc tctcgctgca gcagtggaag   1920

cggccaatgg ggctgagcag acccgagtga acaaagcacc agaagggcgg agccctctga   1980

gcgctgagga gctgatgact attgaggatg aaggagtctt ggacaagatg ctggatcaga   2040

gcacggactt tgaagagcgg aagctcatcc gggctgcact tcgtgagctc cgacaaagga   2100

agagagacca gcgggacaag gagcgggaac ggcggctgca ggaggcacgg ggccggccag   2160

gggaggggcg cggcaacaca gccactgaga ccaccacgag gcacagccag cgggcagctg   2220

atggctctgc tgtcagcact gttaccaaga ctgagcggct cgtccactcc aatgatggca   2280

cacggacggc ccgcaccacc acagtggagt cgagtttcgt gaggcgctcg gagaatggca   2340

gtggcagcac catgatgcaa accaagacct tctcctcttc ctcctcatcc aagaagatgg   2400

gcagcatctt cgaccgcgag gaccaggcca gcccacgggc cggcagcctg gcggcgctcg   2460

agaaacggca ggccgagaag aagaaagagc tgatgaaggc gcagagtctg cccaagacct   2520

cagcctccca ggcgcgcaag gccatgattg agaagctgga gaaggagggc gcggccggca   2580

gccctggcgg accccgcgca gccgtgcagc gatccaccag cttcggggtc cccaacgcca   2640

acagcatcaa gcagatgctg ctggactggt gtcgagccaa gactcgcggc tacgagcacg   2700

tcgacatcca gaacttctcc tccagctgga gtgatgggat ggccttctgt gccctggtgc   2760

acaacttctt ccctgaggcc ttcgactatg ggcagcttag ccctcagaac cgacgccaga   2820

acttcgaggt ggccttctca tctgcggaga cccatgcgga ctgcccgcag ctcctggata   2880

cagaggacat ggtgcggctt cgagagcctg actggaagtg cgtgtacacg tacatccagg   2940

aattctaccg ctgtctggtc cagaaggggc tggtaaaaac caaaaagtcc taacccctgc   3000

tcggggcccc acggatgctg gtggactgtg tgcccctggt ggaggtggac gacatgatga   3060

tcatgggcaa gaagcctgac cccaagtgtg tcttcaccta tgtgcagtcg ctctacaacc   3120

acctgcgacg ccacgaactg cgcctgcgcg gcaagaatgt ctagcctgcc cgcccgcatg   3180

gccagccagt ggcaagctgc cgcccccact ctccgggcac cgtctcctgc ctgtgcgtcc   3240

gcccaccgct gccctgtctg ttgcgacacc ctccccccca catacacacg cagcgttttg   3300

ataaattatt ggttttcaac gaaaaaaaaa aaaaaa                             3336


<210>  962
<211>  2987
<212>  DNA
<213>  Homo sapiens

<400>  962
agcagtgttc tcttcgtccc cctcccccaa actgaggatt gggcaatacc acagaacctc     60

aggaaagggg ggaagagcga gcttcggccc cactaatggg ggagtgggcg gaggctggat    120

ttcccacctc ggctgcacct gggcactgga ggctgaagag gaaagtgaga atctgaagtt    180

ttgagacctc tgactggcca ggaatagctc ctggggcggg gggcaaggat gggaccatag    240

gcggaaagag tctcgcggtc ccccctgctt ctggcgcggg tccctgcgcc cggttgtgga    300

gcgtctcgcg cggggagggg gcggggggaa cggcagctcg cggtgttgtt cactcgcgcg    360

tcgagcacac ggtgggtccg gcggcgggtt ggcgccccag gcggcgttcc ctgtggcctg    420

gcgcctgggc cgctgccctg agcgggttcc gccccagagc ccgaccctcc tgggggctct    480

aggcggagtc ccgcgagccg agggggaccg gcgaccgctg ccgaagcatg aagaaggggt    540

aaggcgtgag cccccaagat ttcacggtga actggcacaa aggttaatct caagatgccg    600

ctagtgaaaa gaaacatcga tcctaggcac ttgtgccaca cagcactgcc tagaggcatt    660

aagaatgaac tggaatgtgt aaccaatatt tccttggcaa atataattag acaactaagt    720

agcctaagta aatatgctga agatatattt ggagaattat tcaatgaagc acatagtttt    780

tccttcagag tcaactcatt gcaagaacgt gtggaccgtt tatctgttag tgttacacag    840

cttgatccaa aggaagaaga attgtctttg caagatataa caatgaggaa agctttccga    900

agttctacaa ttcaagacca gcagcttttc gatcgcaaga ctttgcctat tccattacag    960

gagacgtacg atgtttgtga acagcctcca cctctcaata tactcactcc ttatagagat   1020

gatggtaaag aaggtctgaa gttttatacc aatccttcgt atttctttga tctatggaaa   1080

gaaaaaatgt tgcaagatac agaggataag aggaaggaaa agaggaagca gaagcagaaa   1140

aatctagatc gtcctcatga accagaaaaa gtgccaagag cacctcatga caggcggcga   1200

gaatggcaga agctggccca aggtccagag ctggctgaag atgatgctaa tctcttacat   1260

aagcatattg aagttgctaa tggcccagcc tctcattttg aaacaagacc tcagacatac   1320

gtggatcata tggatggatc ttactcactt tctgccttgc catttagtca gatgagtgag   1380

cttctgacta gagctgagga aagggtatta gtcagaccac atgaaccacc tccacctcca   1440

ccaatgcatg gagcaggaga tgcaaaaccg atacccacct gtatcagttc tgctacaggt   1500

ttgatagaaa atcgccctca gtcaccagct acaggcagaa cacctgtgtt tgtgagcccc   1560

actcccccac ctcctccacc acctcttcca tctgccttgt caacttcctc attaagagct   1620

tcaatgactt caactcctcc ccctccagta cctcccccac ctccacctcc agccactgct   1680

ttgcaagctc cagcagtacc accacctcca gctcctcttc agattgcccc tggagttctt   1740

cacccagctc ctcctccaat tgcacctcct ctagtacagc cctctccacc agtagctaga   1800

gctgccccag tatgtgagac tgtaccagtt catccactcc cacaaggtga agttcagggg   1860

ctgcctccac ccccaccacc gcctcctctg cctccacctg gcattcgacc atcatcacct   1920

gtcacagtta cagctcttgc tcatcctccc tctgggctac atccaactcc atctactgcc   1980

ccaggtcccc atgttccatt aatgcctcca tctcctccat cacaagttat acctgcttct   2040

gagccaaagc gccatccatc aaccctacct gtaatcagtg atgccaggag tgtgctactg   2100

gaagcaatac gaaaaggtat tcagctacgc aaagtagaag agcagcgtga acaggaagct   2160

aagcatgaac gcattgaaaa cgatgttgcc accatcctgt ctcgccgtat tgctgttgaa   2220

tatagtgatt cggaagatga ttcagaattt gatgaagtag attggttgga gtaagaaaaa   2280

tgcattgata aatattacaa aactgaatgc aaatgtcctt tgtggtgctt gttccttgaa   2340

aatgtttggt cattctagtg ttttgctttc ttttccttat aataaatgac ccttttcctc   2400

cataactttt gatttctaag gaaaatatta gcatacattt caaactaaat gttttacagt   2460

ggcttatctt ttttttcccc ctgaaaagac taatttggtc aaataaacca ctaagtatta   2520

agcatggaca gctgttgtta gagtagcaga ttcagttttt tgatatatct taattgtgta   2580

ctttgtgaat tttaatttaa agaaagcaac tgaaattgaa atcttgaggg cagctgtgtc   2640

tactaatgag ccttattcca tttcctgatg ttttaaaaga agaaacactg ccttgattat   2700

acgaatacac tcagaaagta catttagctt gtagtgttga attctcttaa aggaatgctt   2760

gaattttttc attattgttt tattgttttt atatacttgc cttatttgaa tgtttagcag   2820

tatccccttc ccacttatat attgtgtgat atgattttgc ttgcctatag gagttaaaaa   2880

cttttccatg tgaaatactc tgacttaaac atacatgtaa cttacataac tgttaagaat   2940

aacagtctga tttaataaat ggttcatttt aaaagttaaa aaaaaaa                 2987


<210>  963
<211>  3725
<212>  DNA
<213>  Homo sapiens

<400>  963
agcttctcgg tgccgccccg gaagtaacct ctcgctgatc tcgagagcta gctcgagtat     60

cgccctgccc tggctgcgac gtcagctccg cccttataat ctgcgacgtg gccggcttct    120

tctgcccgga gaggacgtca tttccgccga gtccctgacc tgctgctagg atcgcgacgg    180

gaactggagc ccgaggtccc cgcgcggccc gggcctggcg ccctgagggg aagagcggcc    240

cggcccgagc catgacggac gggatcctag ggaaggcagc cacaatggag atccctatcc    300

acgggaacgg cgaagccagg cagcttcctg aagatgatgg gctggagcag gacctccagc    360

aggtgatggt gtcaggaccc aacctcaatg aaaccagcat tgtgtctggt ggctatgggg    420

gctctggtga tggactcatc cccacagggt ctggccgcca tccatctcac agcaccactc    480

cttctggccc tggagatgag gtggctcggg gcattgctgg agaaaagttt gacatcgtca    540

agaaatgggg catcaacacc tataagtgca caaagcaact gttatcagaa cgatttggtc    600

gaggctcacg gactgtggac ctggagctag agctgcagat tgagttgctg cgtgagacga    660

agcgcaagta tgagagtgtc ctgcagctgg gccgggcact gacagcccac ctctacagcc    720

tgctgcagac ccagcatgca ctgggtgatg cctttgctga cctcagccag aagtccccag    780

agcttcagga ggaatttggc tacaatgcag agacacagaa actactatgc aagaatgggg    840

aaacgctgct aggagccgtg aacttctttg tctctagcat caacacattg gtcaccaaga    900

ccatggaaga cacgctcatg actgtgaaac agtatgaggc tgccaggctg gaatatgatg    960

cctaccgaac agacttagag gagctgagtc taggcccccg ggatgcaggg acacgtggtc   1020

gacttgagag tgcccaggcc actttccagg cccatcggga caagtatgag aagctgcggg   1080

gagatgtggc catcaagctc aagttcctgg aagaaaacaa gatcaaggtg atgcacaagc   1140

agctgctgct cttccacaat gctgtgtccg cctactttgc tgggaaccag aaacagctgg   1200

agcagaccct gcagcagttc aacatcaagc tgcggcctcc aggagctgag aaaccctcct   1260

ggctagagga gcagtgagct gctcccagcc caacttggct atcaagaaag acattgggaa   1320

gggcagcccc agggtgtggg agattggaca tggtacatcc tttgtcactt gccctctggc   1380

ttgggctcct ttttctggct ggggcctgac accagttttg cccacattgc tatggtggga   1440

agagggcctg gaggcccaga agttgctgcc ctgtctatct tcctggccac agggcttcat   1500

tcccagatct tttccttcca cttcacagcc aacggctatg acaaaaccac tccctggcca   1560

atggcatcac tcttcaggct ggggtgtgct ccctgaccaa tgacagagcc tgaaaatgcc   1620

ctgtcagcca atggcagctc ttctcggact cccctgggcc aatgatgttg cgtctaatac   1680

cctttgtctc tcctctatgc gtgcccattg cagagaaggg gactgggacc aaaggggtgg   1740

ggataatggg gagccccatt gctggccttg catctgaata ggcctaccct cacccaccca   1800

cccagtttaa ttgtgcttag agcccaagaa gattgggatc tagcactagg aataaacctt   1860

tcataaaagc aggcccagcg aggtcaattt gtcggggact ctaggagggt ggcctgggtg   1920

gagacaagct cagtctaatc aaacaccaga accctatcaa gtcaaaagag ctggggccag   1980

gcagctgaag tcacaggttt cagagatggt ttgaaggccc agtcttctct cccagcctca   2040

gttggagcca aagctttgtc ctttagccag caccaagata gctatggatc ttaagagcac   2100

cagatccaga gggggttggg tttgctgacc ttcatcatgc attcattcat acagcaaata   2160

tttactgagt gctttcattt gccagggact gcgttaggcc ctggggaaac atcagtgaat   2220

aaaacacggt ccctgcccac agtgcttagg gcctactgag ggaaagaagt aaccaggcaa   2280

ctacaaaaca gtgataagta ttaggataca gaagtacaga gggcgctgtg ggagcacaaa   2340

ggaggggcat ctggcatgga ctggggtgga aatggggatg tcagtttgaa agctgagacc   2400

tggccaggtg cggtggctca ctcctgtaat cccagcactt tgggaggccg aggcgggcgg   2460

atcaccaggt caggagatca agaccatcct ggctaacacg gtgaaaaccc atctctacta   2520

aaaatgcaag aaaattagcc cggcacggtg gctggcgcct gtagtcctgt agtcccagct   2580

actcgggagg ctgaggcagg agaatggtgt gaacccggga ggcggagctt gcagtggagc   2640

caagattgcg ccactgcact ccagcctggg caacagagcg ggactccatc tcaaaaaaaa   2700

aaaaaaaaaa gctgagacct gaagggtgag tagatgacaa acaggcaggg taaagggaag   2760

agcatcccag gcagagaggc tagcatataa tgaaggctct gagtaggaac tgggaggaat   2820

tgcttggaat gaaaaatgaa gagggagtgg ctagatgaag actgcaggct ggttaaggac   2880

ttttgccctc tggagaagga gctgagaagt gttttaagca gaaatttgac tgcatgggag   2940

aagtatagag ttgagaaaag tagtcctctg aggcttaaga tagtgtcatc tagactccag   3000

ttccctcatc ttgggtagca tagtagcccc agcccaaaac tgcaagcatg atccccgtct   3060

gggtttcctt cacaagcact ggagcatctt gtgctatgtg ctgaactcag gtggataaga   3120

ggttgaggcg gttcccaaag ctcctgctgc acccaggtgt tgagcctaaa tctgaacctt   3180

gtggagaggt cacaagaaag atccctaaca gcactttggt ttagtcaggg ctaggtgtca   3240

tcacctgtat gccctttggc caaggaaacc agaatttttc aggattttcc ccacctctgg   3300

aaggctggag gaaggggaag acccactcag cagattccca tagtgcaggg atcctcacag   3360

gcatgacttt gccctttgtc atggatactg cagctcccag acagtcttct gggctttgat   3420

cagcctgcaa tcatctgact agagcttgat ttttggggca gggaaggtgg tccttatatg   3480

agctgccact taatgggcca ctggggattt ttcaacatga aaggtaccga gtctccaaat   3540

gctggttgta gggcctaaaa acagggctca actccaggtt ctgccacttt ctagctgagt   3600

gatgagggct aacgtctggg gagcaagatc cctatttttt cccattgtaa aattgggcta   3660

ataaaagatg ctacctactg actattaaat aatatatgta aagtggcaaa aaaaaaaaaa   3720

aaaaa                                                               3725


<210>  964
<211>  7884
<212>  DNA
<213>  Homo sapiens

<400>  964
ccactgagca gccaaccgca gcctctggcc acaaggagag cggagcacag gagcaggaag     60

ccgcctacca ccatgagcag cacgctgtca cccacagact ttgacagctt ggaaatccag    120

ggccagtaca gtgacatcaa caaccgctgg gaccttcctg actcggactg ggacaatgac    180

agcagctcgg cccgcctctt tgagaggtct cgcattaagg ctctggcaga tgaacgagaa    240

gctgtgcaga agaaaacctt caccaagtgg gtaaactcgc acctggcccg ggtcacgtgc    300

cgggtggggg acctgtacag cgacctccgg gacggacgca acctgctgag gctcctcgag    360

gtgctctcgg gagagatact gccaaagcct acaaagggcc gcatgcggat ccactgcctg    420

gagaacgtgg acaaggcact gcagttcctc aaggagcaga aagtgcactt ggaaaacatg    480

ggctcccatg acattgtgga cggaaaccac cgactgaccc ttgggctggt ctggaccatc    540

atccttcgat tccagatcca agacatcagt gtggagacag aagacaacaa ggagaagaag    600

tcagccaagg atgccctgct tctgtggtgc cagatgaaga ctgcaggtta tcccaacgtc    660

aatgtacaca acttcaccac cagctggaga gatggactag ctttcaacgc catcgtgcat    720

aaacaccggc cagacctgct ggattttgag tctctgaaga agtgtaatgc acactataat    780

ctgcagaatg cattcaatct ggctgaaaag gaactgggac ttaccaagct gctggatccc    840

gaagacgtga atgtggacca gccagatgag aagtcaatca ttacctatgt ggctacttac    900

taccattact tctccaagat gaaggccctg gccgtggaag gcaagagaat tggcaaggtg    960

ctggaccatg ccatggaggc agagcgcctg gtggagaaat acgagtccct ggcctcggag   1020

ctgctgcagt ggatcgagca aacgatcgtg accctcaatg accggcagtt ggccaactcc   1080

cttagcgggg tccagaacca gctgcagtcc ttcaactcct accgcaccgt ggagaagccg   1140

cccaagttta ccgagaaagg gaacttggaa gtgctgctct tcaccatcca gagcaagctt   1200

cgggccaaca accagaaggt ctacacgccc cgcgagggcc ggctcatctc ggacatcaac   1260

aaggcttggg agcggctgga gaaggcggag cacgagcgtg agctggccct gcgcaccgag   1320

ctcatccgcc aggagaagct ggagcagctg gccgcccgct tcgaccgcaa ggctgccatg   1380

cgggagacct ggctcagcga gaaccagcgc ctcgtgtccc aggacaactt tgggctggag   1440

ctggcagctg tcgaggcagc agtacggaag cacgaagcca ttgagacgga catcgtggcc   1500

tacagcggcc gggtgcaggc agtggacgcc gtggctgcag agctggccgc cgagcgctac   1560

cacgacatca agcgcatcgc cgctcggcag cacaacgtgg cacggctctg ggacttcttg   1620

cggcagatgg tggccgcccg gcgggagcgg ctcctcctca acctggagct gcagaaggtg   1680

ttccaggacc tgctctacct catggactgg atggaagaga tgaagggccg gctgcagtct   1740

caggacctgg gcaggcacct agcaggagtg gaggacctgc tgcagctgca cgagctggtg   1800

gaggcagaca tcgccgtgca ggccgagagg gtgcgggccg tcagcgcctc tgccctgcgc   1860

ttctgcaacc cagggaaaga gtatagacct tgcgacccgc agctggtgtc ggagcgggtg   1920

gccaagctag agcagagcta tgaggcactg tgcgagttgg cagcggcgcg gcgggcccgg   1980

ctggaggaat cacggcggct ctggcgtttc ctctgggagg tgggtgaagc tgaggcctgg   2040

gtgcgggagc agcagcacct cctggcctca gccgacacgg gccgagacct gaccggtgcc   2100

ctccgcctgc tcaacaagca cacagccctg cggggcgaga tgagcggccg gctggggccc   2160

ctgaagctca ccctggagca gggccagcag ttggtggccg agggtcaccc tggggcaagc   2220

caggcctctg cccgtgcagc tgaactccaa gcccagtggg agcggctaga ggccctggcc   2280

gaggagcgtg cccagcggct ggcccaagcc gccagcctct accagttcca ggccgatgca   2340

aacgacatgg aggcctggtt ggttgacgca ctgcgcctgg tgtccagccc cgagctgggg   2400

cacgacgagt tctccacgca ggctctagcc aggcagcatc gggccctgga ggaggagatt   2460

cgaagccacc ggccaaccct ggacgccttg agggaacagg cagcagccct gccccccaca   2520

ctgagccgca cgcccgaggt gcagggccgg gtgcccaccc tggagcggca ctacgaggag   2580

ctgcaggccc gggcaggcga gcgagcgcgg gccttggagg cagccctggc gctctacacc   2640

atgctcagcg aggccggggc ctgtggactc tgggtggagg agaaggagca gtggctcaac   2700

gggctggccc tgcctgaacg cctggaggac ctggaggtcg tgcagcagag gttcgagacc   2760

ctggagcctg aaatgaacac ccttgcagca caaatcaccg cggtgaatga cattgccgag   2820

cagttactga aggccaaccc cccaggcaaa gaccgcattg tcaacaccca ggagcagctc   2880

aaccacaggt ggcagcagtt tcggcgtctg gcagacggca agaaggcagc tctcacctca   2940

gccctgagca tccagaacta ccacttagag tgcacggaga cccaggcctg gatgagagag   3000

aagaccaaag tcatcgagtc cacccagggc ctaggcaacg atctggctgg ggtgctggcc   3060

ctgcagcgca agctggccgg cacggagcgg gacctggagg ccatcgccgc ccgggtgggc   3120

gaactgactc gagaggcaaa tgccctggct gccggccatc ccgctcaggc agtggccatc   3180

aacgcccggc tgagagaggt gcagaccggc tgggaggacc tcagggccac catgcggcgt   3240

cgagaagagt cgctggggga ggcgcggcgg ctgcaggact tcttgcgcag cttggatgac   3300

ttccaggcct ggctaggccg cactcagact gctgtggcct ctgaagaagg gccggccacc   3360

ctgcctgagg cagaggccct cctggcccaa catgcagccc tgcggggaga ggtggagcgg   3420

gcccagagcg agtatagccg gctgcgagcc ctgggcgagg aggtgacccg ggaccaggct   3480

gacccccagt gcctcttcct acgacagcga ctggaggccc tgggaactgg ctgggaggag   3540

ctgggccgaa tgtgggagag ccggcaaggt cgcctggccc aggcccacgg cttccaggga   3600

ttcctgcggg atgctcgtca ggctgagggc gtgctcagca gccaggaata tgttctgtct   3660

cacacggaga tgccagggac actccaggct gctgatgctg ccattaaaaa actggaggac   3720

ttcatgagca ccatggacgc caatggggaa cggatccacg ggctcctgga ggctggccgc   3780

cagctggtat ctgaaggcaa catccacgcc gacaagattc gggaaaaggc agactccatt   3840

gagaggaggc acaagaagaa tcaagacgca gcgcagcaat ttctgggccg tcttcgggac   3900

aaccgggagc agcagcattt cctgcaagat tgtcacgagc tgaagctctg gatcgacgag   3960

aagatgctga cagcccagga cgtgtcctat gacgaggccc gcaacctgca tactaagtgg   4020

cagaagcacc aggcattcat ggccgagctg gctgccaaca aagactggct ggacaaggtg   4080

gacaaggaag ggcgagagct cacccttgag aagccagagc tgaaagccct ggtgtcggag   4140

aagctgagag acctgcacag gcgctgggac gagctggaga ccaccaccca agccaaggcc   4200

cgcagcctct ttgatgccaa ccgagctgag ctgtttgccc agagctgctg tgccctggag   4260

agctggctgg agagcctgca ggcccagctg cactcggatg actacggcaa ggacctcacc   4320

agcgtcaaca tcctgctcaa gaagcagcag atgctggaat gggagatggc tgtgagagag   4380

aaggaggtgg aggcaatcca ggcccaggcc aaagcactgg cccaggagga ccagggtgca   4440

ggggaggtgg agagaacctc gagggccgtg gaggagaagt tcagggcctt gtgccagccc   4500

atgcgggaac gctgccggcg cctgcaggct tctcgcgagc agcaccagtt ccaccgcgat   4560

gtggaagatg agattttgtg ggtgacagag cggctgccca tggccagctc catggagcat   4620

ggcaaggacc tgcccagcgt ccagcttctc atgaagaaaa accagaccct gcagaaagag   4680

attcagggcc atgagccccg gatcgcggac ctgagggagc ggcagcgtgc tctaggtgca   4740

gcagcagcag gtccagagct ggctgagctg caggaaatgt ggaaacgcct gggccacgag   4800

ctggaacttc gagggaagcg actggaggat gccctgcgag cccagcagtt ctaccgcgat   4860

gccgccgagg cggaggcctg gatgggcgag caggaattac acatgatggg ccaggagaag   4920

gccaaggatg agctgagtgc ccaggcagag gtgaagaagc accaggtgct ggagcaagcc   4980

ctggccgact acgcgcagac catccaccag ctggcggcca gcagccagga catgattgac   5040

cacgagcacc cagagagcac tcggatatcc atccgccaag cccaggtgga caagctgtat   5100

gccggcctga aggagctggc tggagagcgg cgggagcgcc tgcaggagca cctccggctg   5160

tgccagctcc gccgcgagct ggatgacctg gaacagtgga tccaggagcg cgaggtggtg   5220

gcggcctccc acgagctggg ccaggactac gagcatgtga ctatgctccg agacaaattc   5280

cgagagttct cccgggacac aagcaccatc ggtcaggagc gcgtagatag cgccaatgcg   5340

ctggccaatg ggctcattgc tgggggccat gctgcacggg ccaccgtggc cgagtggaag   5400

gacagtctca acgaggcctg ggctgacctg cttgagctgc tggacacacg gggtcaggtg   5460

ctggccgcgg cgtacgagct gcagcgcttc ctgcacgggg cacgccaagc cctggcgcgg   5520

gtgcagcaca agcagcagca gcttccggac gggactggcc gcgacctcaa cgctgccgag   5580

gccctgcagc gccgacactg tgcctacgag catgacattc aggccctcag cccccaggtc   5640

cagcaggtgc aggacgacgg ccaccggctc cagaaggcct acgctggaga caaggctgag   5700

gagatcggcc gccacatgca ggccgtggcc gaggcctggg cccagcttca gggaagctct   5760

gccgcccgcc ggcagctgct gctggacacc acagacaagt tccgcttctt caaggctgtc   5820

cgggaactga tgctctggat ggatgaggtc aacctgcaga tggatgccca ggagcgtccc   5880

cgggatgtgt cctccgcgga tctagtcatc aagaaccagc aaggcatcaa ggcagagata   5940

gaggcccggg cagaccgctt ctcctcctgc atcgacatgg ggaaggagct gctggccagg   6000

agccactatg cggccgagga gatctcagag aagctgtctc agctgcaggc acggcgccag   6060

gagacagctg agaagtggca ggagaagatg gactggcttc agctggtttt ggaggtgctt   6120

gtgtttggaa gagatgcagg gatggcagag gcctggctct gcagccagga gccactggtg   6180

cgcagcgctg agctgggttg cacggtcgac gaagttgaga gcctcatcaa gcggcacgag   6240

gccttccaga agtcagcagt ggcctgggag gagcgattct gtgcgctgga gaagcttact   6300

gcgctagagg agcgggagaa ggagcgaaag agaaagaggg aggaggagga gcggcggaaa   6360

cagccgcctg ctcccgaacc cacagccagt gtgcctccag gggacctggt gggcggccag   6420

acagcttctg acaccacctg ggacggaacc cagccacggc caccaccatc cacacaagca   6480

cccagtgtta atggagtctg cacagatgga gagccctcac agcccctgct gggacaacag   6540

agacttgagc acagcagctt ccccgaaggg ccgggacctg gctcagggga cgaagccaat   6600

gggccccggg gagagaggca gacccggact cggggcccgg ccccatctgc aatgccccag   6660

agcaggtcta ccgagtcagc ccatgctgcc accctgccgc ctcgaggccc agagccatct   6720

gcccaggagc agatggaggg gatgctgtgc cgcaagcagg agatggaggc cttcgggaag   6780

aaggctgcca acaggtcctg gcagaacgtg tactgtgtcc tgcggcgtgg gagcctcggc   6840

ttttacaagg atgccaaggc agccagcgcg ggagtgccat accacggaga agtgcctgtc   6900

agcctggcca gggcccaggg cagcgtcgcc tttgattacc gaaagcgcaa acatgtcttc   6960

aagctgggct tacaggatgg aaaagaatat ttattccagg ccaaggatga ggcagagatg   7020

agctcgtggc tacgggtggt gaatgcagcc attgccacag cgtcttctgc ctctggagag   7080

cctgaagagc cggtggtgcc cagcaccacc cggggcatga cccgggccat gaccatgccc   7140

ccagtgtcac ccgtcggggc tgaggggcct gttgtgctcc gcagcaaaga cggcagagaa   7200

cgagagcgag aaaaacgctt cagcttcttt aagaagaaca agtagttggg ggcaaggtcc   7260

caggccaact ccctccctcc gttcaggaaa ctgccaggga cagtcgacag ggaccgccct   7320

cttgtcagga caactgcctg ctgctagggt ctgttgccaa ggtcaaccca tcaccaggaa   7380

ctgtcactgg ggacgagtcc atgttcccaa gggcagccct tctcttctgc tgtttaattc   7440

cagactggtg gtgggaccca ggtaaccccc tctcccaccc ccgccgactt ctcccctttc   7500

cccagcctcg tgcctctgtc cctcaccacg gtgtggacag tgccgcaccc tcaacatagg   7560

ccatgtgggg agtggctgcc cctgcctcag ggtcattctc ctgccatgcg agggcactcg   7620

ccttctgcct tctggttcct cacccctcag accagccagg aacctctcag agctgaagca   7680

ggccctgggg gcagaagtgc cagatgacag tcagaggcgc aggagccctc cctccccacc   7740

cccaccctgt aactccagct gccactccat ctccagctgc tctcaatggc ttccaggtgt   7800

gttgttcggg gacagccacc gccttgagtc tggccaagga ggtgattaaa cagctcagct   7860

tctctcaaaa aaaaaaaaaa aaaa                                          7884


<210>  965
<211>  2298
<212>  DNA
<213>  Homo sapiens

<400>  965
gagccgcgta gaaggaacgc ggcggtgtgc cccggaagcg gaagtagatt ctcctataga     60

aaggctggac tacgcggagt ggtgacgttt cctcattggg cggaaggttc gctggcactc    120

cgttggtctt ccagctggtg ggagttgacg acgtggtgct gggcgttggg accctacttt    180

atctagttcg ggaagttggg ttgtggggtc atacctgtct gtctgctccc agctttcttg    240

ggtttcttcc gacggcgtgg ggcctcgcta aggaattccc ggcccctcag ggccacggct    300

ttagcggtgt cttttgcgag ttcttcgtaa gtacatctta aagctgtcaa gatggttcta    360

gcagaccttg gaagaaaaat aacatcagca ttacgctcgt tgagcaatgc caccattatc    420

aatgaagagg tattgaatgc tatgctaaaa gaagtctgta ccgctttgtt ggaagcagat    480

gttaatatta aactagtgaa gcaactaaga gaaaatgtta agtctgctat tgatcttgaa    540

gagatggcat ctggtcttaa caaaagaaaa atgattcagc atgctgtatt taaagaactt    600

gtgaagcttg tagaccctgg agttaaggca tggacaccca ctaaaggaaa acaaaatgtg    660

attatgtttg ttggattgca agggagtggt aaaacaacaa catgttcaaa gctagcatat    720

tattaccaga ggaaaggttg gaagacctgt ttaatatgtg cagacacatt cagagcaggg    780

gcttttgacc aactaaaaca gaatgctacc aaagcaagaa ttccatttta tggaagctat    840

acagaaatgg atcctgtcat cattgcttct gaaggagtag agaaatttaa aaatgaaaat    900

tttgaaatta ttattgttga tacaagtggc cgccacaaac aagaagactc tttgtttgaa    960

gaaatgcttc aagttgctaa tgctatacaa cctgataaca ttgtttatgt gatggatgcc   1020

tccattgggc aggcttgtga agcccaggct aaggctttta aagataaagt agatgtagcc   1080

tcagtaatag tgacaaaact tgatggccat gcaaaaggag gtggtgcact cagtgcagtc   1140

gctgccacaa aaagtccgat tattttcatt ggtacagggg aacatataga tgactttgaa   1200

cctttcaaaa cacagccttt tattagcaaa cttcttggta tgggcgacat tgaaggactg   1260

atagataaag tcaacgagtt gaagttggat gacaatgaag cacttataga gaagttgaaa   1320

catggtcagt ttacgttgcg agacatgtat gagcaatttc aaaatatcat gaaaatgggc   1380

cccttcagtc agatcttggg gatgatccct ggttttggga cagattttat gagcaaagga   1440

aatgaacagg agtcaatggc aaggctaaag aaattaatga caataatgga tagtatgaat   1500

gatcaagaac tagacagtac ggatggtgcc aaagttttta gtaaacaacc aggaagaatc   1560

caaagagtag caagaggatc gggtgtatca acaagagatg ttcaagaact tttgacacaa   1620

tataccaagt ttgcacagat ggtaaaaaag atgggaggta tcaaaggact tttcaaaggt   1680

ggcgacatgt ctaagaatgt gagccagtca cagatggcaa aattgaacca acaaatggcc   1740

aaaatgatgg atcctagggt tcttcatcac atgggtggta tggcaggact tcagtcaatg   1800

atgaggcagt ttcaacaggg tgctgctggc aacatgaaag gcatgatggg attcaataat   1860

atgtaaagaa aatgccttaa tataaactga ctcagttgaa tacctaattt gctgagacct   1920

cagcgtttcc cttctttttg cgaattgggg ggaaagtgta tttttcttgc ttatcatgca   1980

ctctttcctt ttcttctcgc ccgcttttcc cctccttttc tttttccttc cttctttcct   2040

ccctttaata taagggagaa atacatggtt tttgtggaaa tcattatatg tttgctttag   2100

attttcttct gttttcacca tcataacact taagttaaat catgatgtaa aattttagta   2160

cttaaaggtt tttaattatc tcgaaggcca agcattgcat ttgtaaacag tcctggtcag   2220

tagttaaata atgtttcaat taaagtgctg taaaataaac ttcaaagtgg ttataagtta   2280

aaaaaaaaaa aaaaaaaa                                                 2298


<210>  966
<211>  4157
<212>  DNA
<213>  Homo sapiens

<400>  966
gaggccgcgc ggggcccggg cttcggccga tcagcccggg aggccccgcc gcgccccctt     60

ggcccgcgcg cccgtggtca cagtggaaga ggcgcccgcg ctgcgctgcc cggaggagcc    120

gtcgcgcgcc cgcttcctgt tcggctggtt cctgccagct cgaggacaaa acacgcgtgc    180

gcgcggcggg cgagcgcgct cgccgcctca gtcgccagcg ccgggcgcag tccgcctttt    240

tccggagcag actggccgcg gtgctagtcg gtagcagcgg ccgccgcagc ggctccgcac    300

tggcgaaccg agggcagaaa aaggcggggt tgacggcttt ttggtaggag tgggctggac    360

cggacgccag agacaaaggc tcccaaggca agagggactg tggccctgcg tcggctctgc    420

tcgggactgc tgaccccagg aatttacgcc ccttcgtttt tctcttctga ttcttctctt    480

ctcccaagcc cgcgtcccct cacgcgtggc ctctctcctt gccgggaggg ccgcgatgga    540

ggtcccgccc aggctttccc atgtgccgcc gccattgttc ccctccgctc ccgctacttt    600

agcctcccgc agcctctccc attggcggcc gcggccgccg cggcagctag ccccgctcct    660

cccttcgctc gctcccagct ccgcccggca gggggcgcgc cgggcccagc gccacgtcac    720

cgcccagcag ccctcccgat tggcgggcgg ggcggctata aagggagggc gcaggcggcg    780

cccggatctc ttccgccgcc attttaaatc cagctccata caacgctccg ccgccgctgc    840

tgccgcgacc cggactgcgc gccagcaccc ccctgccgac agctccgtca ctatggagga    900

tatgaacgag tacagcaata tagaggaatt cgcagaggga tccaagatca acgcgagcaa    960

gaatcagcag gatgacggta aaatgtttat tggaggcttg agctgggata caagcaaaaa   1020

agatctgaca gagtacttgt ctcgatttgg ggaagttgta gactgcacaa ttaaaacaga   1080

tccagtcact gggagatcaa gaggatttgg atttgtgctt ttcaaagatg ctgctagtgt   1140

tgataaggtt ttggaactga aagaacacaa actggatggc aaattgatag atcccaaaag   1200

ggccaaagct ttaaaaggga aagaacctcc caaaaaggtt tttgtgggtg gattgagccc   1260

ggatacttct gaagaacaaa ttaaagaata ttttggagcc tttggagaga ttgaaaatat   1320

tgaacttccc atggatacaa aaacaaatga aagaagagga ttttgtttta tcacatatac   1380

tgatgaagag ccagtaaaaa aattgttaga aagcagatac catcaaattg gttctgggaa   1440

gtgtgaaatc aaagttgcac aacccaaaga ggtatatagg cagcaacagc aacaacaaaa   1500

aggtggaaga ggtgctgcag ctggtggacg aggtggtacg aggggtcgtg gccgaggtca   1560

gggccaaaac tggaaccaag gatttaataa ctattatgat caaggatatg gaaattacaa   1620

tagtgcctat ggtggtgatc aaaactatag tggctatggc ggatatgatt atactgggta   1680

taactatggg aactatggat atggacaggg atatgcagac tacagtggcc aacagagcac   1740

ttatggcaag gcatctcgag ggggtggcaa tcaccaaaac aattaccagc catactaaag   1800

gagaacattg gagaaaacag gaggagatgt taaagtaacc catcttgcag gacgacattg   1860

aagattggtc ttctgttgat ctaagatgat tattttgtaa aagactttct agtgtacaag   1920

acaccattgt gtccaactgt atatagctgc caattagttt tctttgtttt tactttgtcc   1980

tttgctatct gtgttatgac tcaatgtgga tttgtttata cacattttat ttgtatcatt   2040

tcatgttaaa cctcaaataa atgcttcctt atgtgattgc ttttctgcgt caggtactac   2100

atagctctgt aaaaaatgta atttaaaata agcaataatt aaggcacagt tgattttgta   2160

gagtattggt ccatacagag aaactgtggt cctttataaa tagccagcca gcgtcaccct   2220

cttctccaat ttgtaggtgt attttatgct cttaaggctt catcttctcc ctgtaactga   2280

gatttctacc acacctttga acaatgttct ttcccttctg gttatctgaa gactgtcctg   2340

aaaggaagac ataagtgttg tgattagtag aagctttcta gtagaccata tttcttctgg   2400

attgtaataa aattgttagt agctcctttt actttgttcc tgtctctgga aagccatttt   2460

tgaattgctg attactttgg ctttaatcag tggtcaccta gaaaaagctt tgtaatcata   2520

acacaatgag taattcttga taaaagttca gatacaaaag gagcactgta aaactggtag   2580

gagctatggt ttaagagcat tggaagtagt tacaactcaa ggattttggt agaaaggtat   2640

gagtttggtc gaaaaattaa aatagtggca aaataagatt tagttgtgtt ttctcagagc   2700

cgccacaaga ttgaacaaaa tgttttctgt ttgggcatcc tgaggaagtt gtattagctg   2760

ttaatgctct gtgagtttag aaaaagtctt gatagtaaat ctagtttttg acacagtgca   2820

tgaactaagt agttaaatat ttacatattc agaaaggaat agtggaaaag gtatcttggt   2880

tatgacaaag tcattacaaa tgtgactaag tcattacaaa tgtgactgag tcattacagt   2940

ggaccctctg ggtgcattga aaagaatccg ttttatatcc aggtttcaga ggacctggaa   3000

taataaaaag ctttggattt tgcattcagt gtagttggat tttgggacct tggcctcagt   3060

gttatttact gggattggca tacgtgttca caggcagagt agttgatctc acacaacggg   3120

tgatctcaca aaactggtaa gtttcttatg ctcatgagcc ctcccttttt ttttttaatt   3180

tggtgcctgc aactttctta acaatgattc tacttcctgg gctatcacat tataatgctc   3240

ttggcctctt ttttgctgct gttttgctat tcttaaactt aggccaagta ccaatgttgg   3300

ctgttagaag ggattctgtt cattcaacat gcaactttag ggaatggaag taagttcatt   3360

tttaagttgt gttgtcagta ggtgcggtgt ctagggtagt gaatcctgta agttcaaatt   3420

tatgattagg tgacgagttg acattgagat tgtccttttc cctgatcaaa aaatgaataa   3480

agccttttta aacaaaatcc aaacttttaa tcaagtcttg atatgtatga ctgagaaaaa   3540

atacactaca tctagagatg attgagatgt tttgcaaaga attgaagggg gagtgagaat   3600

tggtttttct tgcaggggct ttgaactcta gatttgggct ttgaactcta gatttaattc   3660

agatttcagg gtctatcagt tcaccaactg atgcaaattt gaacagatac tctaaggcta   3720

agtgtcctag gttggatgaa ctgaagctac tatcaagatc tcgttcccaa ggattaattt   3780

agaacaaagt aattggacaa gtttattggg gaggggatag aaatgaattc taaagtacct   3840

ataacaaata ctctgtgtat gttttttaca tcgtatttgc cttttacatt gtttagacca   3900

aattctgtgt gatgttatcc tcgggaagag gatagaaatt aattctaaag tacctataac   3960

aaatgctcgg tttgtatatg tttttataca tcgtatttgc cttttgcatt gttcagacca   4020

aattctgtgt gatgttatcc taacaaaaca ccttagtaat ttctttggtt aacatgttaa   4080

tctgtaatct cacttttata agatgaggac tattaaaatg agatgtctgt tgggatgcta   4140

aaaaaaaaaa aaaaaaa                                                  4157


<210>  967
<211>  1460
<212>  DNA
<213>  Homo sapiens

<400>  967
tgcagcgcag gtgagctctc ctgaggacct ctctgtcagc tcccctgatt gtagggagga     60

tccagtgtgg caagaaactc ctccagccca gcaagcagct caggatgttc ctgaaggccg    120

tggtcctgac cctggccctg gtggctgtcg ccggagccag ggctgaggtc agtgctgacc    180

aggtggccac ggtgatgtgg gactacttca gccagctgag caacaatgcc aaggaggccg    240

tggaacatct ccagaaatct gaactcaccc agcaactcaa tgccctcttc caggacaaac    300

ttggagaagt gaacacttac gcaggtgacc tgcagaagaa gctggtgccc tttgccaccg    360

agctgcatga acgcctggcc aaggactcgg agaaactgaa ggaggagatt gggaaggagc    420

tggaggagct gagggcccgg ctgctgcccc atgccaatga ggtgagccag aagatcgggg    480

acaacctgcg agagcttcag cagcgcctgg agccctacgc ggaccagctg cgcacccagg    540

tcagcacgca ggccgagcag ctgcggcgcc agctgacccc ctacgcacag cgcatggaga    600

gagtgctgcg ggagaacgcc gacagcctgc aggcctcgct gaggccccac gccgacgagc    660

tcaaggccaa gatcgaccag aacgtggagg agctcaaggg acgccttacg ccctacgctg    720

acgaattcaa agtcaagatt gaccagaccg tggaggagct gcgccgcagc ctggctccct    780

atgctcagga cacgcaggag aagctcaacc accagcttga gggcctgacc ttccagatga    840

agaagaacgc cgaggagctc aaggccagga tctcggccag tgccgaggag ctgcggcaga    900

ggctggcgcc cttggccgag gacgtgcgtg gcaacctgag gggcaacacc gaggggctgc    960

agaagtcact ggcagagctg ggtgggcacc tggaccagca ggtggaggag ttccgacgcc   1020

gggtggagcc ctacggggaa aacttcaaca aagccctggt gcagcagatg gaacagctca   1080

ggcagaaact gggcccccat gcgggggacg tggaaggcca cttgagcttc ctggagaagg   1140

acctgaggga caaggtcaac tccttcttca gcaccttcaa ggagaaagag agccaggaca   1200

agactctctc cctccctgag ctggagcaac agcaggaaca gcagcaggag cagcagcagg   1260

agcaggtgca gatgctggcc cctttggaga gctgagctgc ccctggtgca ctggccccac   1320

cctcgtggac acctgccctg ccctgccacc tgtctgtctg tctgtcccaa agaagttctg   1380

gtatgaactt gaggacacat gtccagtggg aggtgagacc acctctcaat attcaataaa   1440

gctgctgaga atctagcctc                                               1460


<210>  968
<211>  4780
<212>  DNA
<213>  Homo sapiens

<400>  968
gcagtcgccg gcggttgcct cgcggggttg cggcgagccc ggcccgcgaa cgtcacgtcc     60

ctgcgcgctc cctgcactct cccgagctgc gctaggcggg cgccacggct gcccggcgaa    120

ggaaaccgaa accgagtccg ggcccgtccc tccgcggccc catccgcccg gtgcacccgg    180

ggccgcgctc gccaggccgc ggagcccaga gctgcgcgca cgaaccgtgc gccgggaggg    240

cgtgggcgtg gcgccgaagg gtcccgggtc ttcgacgcct ctgcggcggc tcctccctcc    300

ttgcagttgg atccctggcg ggtgcggccc ggcccggccc gtgagcggcg cacagaatgg    360

gccgatgctg cttctacacg gcggggacgt tgtccctgct cctgctggtg accagcgtca    420

cgctgctggt ggcccgggtc ttccagaagg ctgtagacca gagtatcgag aagaaaattg    480

tgttaaggaa tggtactgag gcatttgact cctgggagaa gccccctctg cctgtgtata    540

ctcagttcta tttcttcaat gtcaccaatc cagaggagat cctcagaggg gagacccctc    600

gggtggaaga agtggggcca tacacctaca gggaactcag aaacaaagca aatattcaat    660

ttggagataa tggaacaaca atatctgctg ttagcaacaa ggcctatgtt tttgaacgag    720

accaatctgt tggagaccct aaaattgact taattagaac attaaatatt cctgtattga    780

ctgtcataga gtggtcccag gtgcacttcc tcagggagat catcgaggcc atgttgaaag    840

cctatcagca gaagctcttt gtgactcaca cagttgacga attgctctgg ggctacaaag    900

atgaaatctt gtcccttatc catgttttca ggcccgatat ctctccctat tttggcctat    960

tctatgagaa aaatgggact aatgatggag actatgtttt tctaactgga gaagacagtt   1020

accttaactt tacaaaaatt gtggaatgga atgggaaaac gtcacttgac tggtggataa   1080

cagacaagtg caatatgatt aatggaacag atggagattc ttttcaccca ctaataacca   1140

aagatgaggt cctttatgtc ttcccatctg acttttgcag gtcagtgtat attactttca   1200

gtgactatga gagtgtacag ggactgcctg cctttcggta taaagttcct gcagaaatat   1260

tagccaatac gtcagacaat gccggcttct gtatacctga gggaaactgc ctgggctcag   1320

gagttctgaa tgtcagcatc tgcaagaatg gtgcacccat cattatgtct ttcccacact   1380

tttaccaagc agatgagagg tttgtttctg ccatagaagg catgcaccca aatcaggaag   1440

accatgagac atttgtggac attaatcctt tgactggaat aatcctaaaa gcagccaaga   1500

ggttccaaat caacatttat gtcaaaaaat tagatgactt tgttgaaacg ggagacatta   1560

gaaccatggt tttcccagtg atgtacctca atgagagtgt tcacattgat aaagagacgg   1620

cgagtcgact gaagtctatg attaacacta ctttgatcat caccaacata ccctacatca   1680

tcatggcgct gggtgtgttc tttggtttgg tttttacctg gcttgcatgc aaaggacagg   1740

gatccatgga tgagggaaca gcggatgaaa gagcacccct cattcgaacc taaacattgc   1800

ctttgcttgg tgaagaaact gtgtgagctg tcctgacctg gacgatgacg tggggaaacc   1860

ctccacctcc ttgcaggctt gttgcctgtt gaaagaagga aaaagacacg gcgctggcaa   1920

gtgataggaa cattctggcc agaggttaaa gagcaggctg acatggctgg ccattaagct   1980

ttataaaatc atgtgggctc tgaaattgtt cttttatgtg tctagcaagt atttaataaa   2040

cccttgtata gtaattttgt tgttgttggg tgctggtagc tccagaattt tgtgaccact   2100

attgtgggta aaatgtctct gcatcacttg ttaatgctac tggtctaact tcattcagta   2160

tgcttcattc accgaacttt gtgctcaaaa tgcgtatata ccattttatg ttgtattcct   2220

ccatttcact tgcaaaacag aagtaaataa gagttcggga cccagggtaa aatggtagct   2280

tcatccaata tatcattcaa atgcatctga tttctaaaac atattacatt ttatgctgat   2340

cttcagttca taattcttcc aggaaaactc agtcttccaa ctgcaataaa atactgggta   2400

gaatcaaatg ggaaaggggt tgggtggggc aatacccatg agttgatagt gataagctcc   2460

taaggatttt taacttgtac ttttgtgaac gaagagaatg cataaataat gttggtgagg   2520

ataaagtaca gatatttcat gtagaattaa ttgctagtta tgatgcttgt ggatagttaa   2580

ctgttttttt tttagtcaaa atgatcatgc tacgaaaaga tgcttctgag agaatgtaat   2640

gagtaactga tttttcttcc tgagtcgccc ttgccaaata tgttactgta ttaattaatc   2700

taatattgag tgattatttg taaaattatg aatatgggaa atccatctat ctacagccta   2760

agttacacat aagtttcaga aagtctgatt agactaaaga gatatttctt ctgggacagc   2820

cgccttcttg gtaattttga agttcttttt acaagttcct tcctcagttt cagttctttc   2880

cagtgttttg tagctcactg tcactcactg aatagagaaa cgtgtgccct atacttcctg   2940

tgacaatcat tttgctgaca gaatgatgga tgtttaaaat attgcacaaa gtactttaaa   3000

gaaaggtctg ttaggaccag aagcagagac accacttttc aaaggacttc ttggtttcag   3060

cataacctaa gacagggaat tgggagccat catatgtcac agtgttcaga attcaagcat   3120

atttaagggc attttctttg attctcaaag ttcagcattc attttgaatt gagaagccta   3180

tacatttagc tgacaaagtg cttatagaat ttcttaacaa ctgaaccatt caaaaggatt   3240

ttttttgttt aaaactggat ttcaatgtaa gcaaatgaag aaaaaaatat agatttcatt   3300

tccatagctt cttatccctg tattgaggta ataaattgtt ttactgacaa tttttccttt   3360

ttctacacta aaacaatatg tgatatattt cccctcttga agaggcaatt cattaaactc   3420

tcaaattttc tatagaatca agatagaacc tttagatact ccaactcacc aaaatgtaaa   3480

aaaactaaca aaaatatttg gtcttcaata atgctaaata tctacatttt tagaatttat   3540

caacatttaa ctagataatt gggcatgtct taattatgca tgtacttatc catactaata   3600

aaattgacaa tgctagtgca tacttattgg tttagtccta ttatcaggat ataatcatct   3660

gtgaggagga tattttaaat actgtaaatg ataacagtta atgatataca catttagact   3720

gagttgcaca ctggcaggga gaccaaaaac attacttcca tacttgtgtc atgattcttt   3780

tttttttgag agagtctcac tctgtcgcca ggctggagta cagtggcatg atctcggctc   3840

actgcaacct ctgcctcccg ggttcaagca attctcctgc ctcagccacc caagtagctg   3900

ggactacagg tgcgtgccac cacgcccagc taaattttgt atttttagtg gagacggggt   3960

ttcaccatgt tggccaggat ggtctcaatc tcctgaccct gcgatctgcc cacctcagcc   4020

tcccaaagtg ctgggattac aggcgtaagc caccgggcct ggcctgtttt atgattctta   4080

atagttactt ggtttaaatc acatttgata ctatccttct gaaaagtctg agacagatct   4140

acaaactaca gtcaaaatta tagattaaga ggaatgaatg cacctatttg gctttaagtt   4200

gaagatgaat tatttctcat gctcattttc ttgcggcagt tatcttagaa agacccccaa   4260

aggctttgtg attgtaagca ctgtcatgat cacagaatgc aagcttctgg taccatgatc   4320

ctcaacttag agaggaagaa accaagacag agagcttaac tcacttctct cagggaaaat   4380

taggagttga gcacaggaca ggaaatgggc tttgccactt ttagctccag gcttttctaa   4440

ccagacttga tttcctcatg ttctagaaag atcactaatg gtcaagtgga acaagcacta   4500

cacgactaac ccctattggg gtttttaact taagggaggc taatttttaa tttaaactgc   4560

tcgagatatg agttctgcaa aaggtggtcc gcatccttgg ccctctggac attatcacta   4620

aattgcttgt gcctgttaac aagaatactg accagaatgc tcttcatgta gcttatacag   4680

ttggttcact tcatgcggtt cttgacatgt ttatttctac ccttaatgca atgaaatgtt   4740

tcattaataa aaaaccactt tatataaaaa aaaaaaaaaa                         4780


<210>  969
<211>  3226
<212>  DNA
<213>  Homo sapiens

<400>  969
aggaatgggg cggggactag gccttcgcct cggcggcaga ggagactcgg gggccatttt     60

gtgaagagac gaagactgag cggttgtggc cgcgttgccg acctccagca gcagtcggct    120

tctctacgca gaacccggga gtaggagact cagaatcgaa tctcttctcc ctccccttct    180

tgttttcggc tttgtgagaa accttaccat caaacacgat ggccagcaac gttaccaaca    240

agacagatcc tcgctccatg aactcccgtg tattcattgg gaatctcaac actcttgtgg    300

tcaagaaatc tgatgtggag gcaatctttt cgaagtatgg caaaattgtg ggctgctctg    360

ttcataaggg ctttgccttc gttcagtatg ttaatgagag aaatgcccgg gctgctgtag    420

caggagagga tggcagaatg attgctggcc aggttttaga tattaacctg gctgcagagc    480

caaaagtgaa ccgaggaaaa gcaggtgtga aacgatctgc agcggagatg tacgggtcag    540

taacagaaca cccttctccg tcccctctac tcagctcctc ttttgacttg gactatgact    600

ttcaacggga ctattatgat aggatgtaca gttacccagc acgtgtacct cctcctcctc    660

ctattgctcg ggctgtagtg ccctcgaaac gtcagcgtgt atcaggaaac acttcacgaa    720

ggggcaaaag tggcttcaat tctaagagtg gacagcgggg atcttccaag tctggaaagt    780

tgaaaggaga tgaccttcag gccattaaga aggagctgac ccagataaaa caaaaagtgg    840

attctctcct ggaaaacctg gaaaaaattg aaaaggaaca gagcaaacaa gcagtagaga    900

tgaagaatga taagtcagaa gaggagcaga gcagcagctc cgtgaagaaa gatgagacta    960

atgtgaagat ggagtctgag gggggtgcag atgactctgc tgaggagggg gacctactgg   1020

atgatgatga taatgaagat cggggggatg accagctgga gttgatcaag gatgatgaaa   1080

aagaggctga ggaaggagag gatgacagag acagcgccaa tggcgaggat gactcttaag   1140

cacatagtgg ggtttagaaa tcttatccca ttatttcttt acctaggcgc ttgtctaaga   1200

tcaaattttt caccagatcc tctcccctag tatcttcagc acatgctcac tgttctcccc   1260

atccttgtcc ttcccatgtt cattaattca tattgccccg cgcctagtcc cattttcact   1320

tcctttgacg ctcctagtag ttttgttaag tcttaccctg taatttttgc ttttaatttt   1380

gatacctctt tatgacttaa caataaaaag gatgtatggt ttttatcaac tgtctccaaa   1440

ataatctctt gttatgcagg gagtacagtt cttttcattc atacataagt tcagtagttg   1500

cttccctaac tgcaaaggca atctcattta gttgagtagc tcttgaaagc agctttgagt   1560

tagaagtatg tgtgttacac cctcacatta gtgtgctgtg tggggcagtt caacacaaat   1620

gtaacaatgt atttttgtga atgagagttg gcatgtcaaa tgcatcctct agaaaaataa   1680

ttagtgttat agtcttaaga tttgttttct aaagttgata ctgtgggtta tttttgtgaa   1740

cagcctgatg tttgggacct tttttcctca aaataaacaa gtccttatta aaccaggaat   1800

ttggagaaaa aaaaaaccct ggttttttat ttttgtattt tattattgtt tacttcaaac   1860

tttgttttac agcgtcctcc acaaaacctc tagaatgcac tagatatatt tttcttggag   1920

tcataatcat gatgcatacc aacacaacac tactcaaatt atatttcatt gagatgcatg   1980

ttgcattgag gagtcaactt gacatagagt ggagactttt tcaaaatggc ttttacatcc   2040

taatgaaagt ttgggaagta tatcctctct gccttttcat cagtgctttg tggtccagct   2100

ggcacccttt ctgaggtttg tgttttgtgc taaatggttt tgtccttaaa taggagaggc   2160

tcaaaaacat caagatttca ggaaaatggc gacagctgca taatggaacc cccctgcttc   2220

tattttgttc ttttaattac tatttatagc cccagttacc ttctgaattc tgaagtgtat   2280

atacctccat gttcctgaaa acaagaaaac tcttacttcc tgatattcca tagactgcct   2340

tcccaggtga ttgagaacat agagaatgtt acacatttat tttactctaa atgatctttt   2400

acccctgtta gctaatcttt gtgttttcct caactttatt aattacagtg attgcatttt   2460

tagcatccag ttgtaagatg aatatattaa acagctacca gtgttggtga tacctcatcc   2520

ttgaaaggct tagttcattt gtgttttata cttcagtttt tccagcatag cagaaaatgc   2580

cgcttataat ttttgtgcac acaaaccttg gattcccctg taaagttgct attgtttcat   2640

agcatgcggc actggccttt tttcatccta ctcattacag gcaaaactca tgtcttattt   2700

atgaggattt tatagatcat tttctgtaac aggtgacaaa agcagaaaag aatgaagagg   2760

ctgaagtatg aactaccctt ggagcccata tacatgatat aggcaatttc ttttgtatgt   2820

taattcagtc aaaaatacta cccacttgat gttttctaat ctgatgtgag ctcatgttac   2880

acagactttt agtaagtaac ccgtgactag aaaataaact ggatgcttag gagagagtgt   2940

cagatgtata agatgctaat aaaacctgtt taatattatt gttagctgta agtttttggg   3000

aaatactgaa caaattagtc cacaatcaag tgtctacttt tcccttcact gtagggcctc   3060

tccctgcaca gagcagtctg tttagctgtg aacaccacaa tctgcagatg ttcaagtccc   3120

ttacataaaa tggcatagta tttatatgta acctatgcat attctcctgt atattttaaa   3180

tcatctctac attaaaatac ctgataaaat gtaaatggta tgtaaa                  3226


<210>  970
<211>  2667
<212>  DNA
<213>  Homo sapiens

<400>  970
gtggggagtt ggctccgccc tcctcccacg cccggttccc gtagccttag ctctcggccc     60

cgggcccttt ttcctcctcg gctgcgccgc gtgtcctcgg agcgcggtcc ctgtattggt    120

ctcctgctcc tagaggttga gaacaaaaac atgcacctgg agtttccccg gagccctctg    180

cgtggttgag cttcggtgga atttcggggc tcttggctgc cagccgcgct tgcctggtag    240

caacagaaac cagtcctgct cgcctccgtg gacatttcat taccatccag aagtgtctcc    300

cactgaaggc atccgtggtt gtttttaagc cacaaaaaag ccacacccaa gatcacctga    360

cacccaccct gacaagtgtc catgatgctg ggccctgagg gaggtgaagg ctttgtggtc    420

aagctccgtg gcctgccctg gtcctgctct gttgaggacg tgcagaactt cctctctgac    480

tgcacgattc atgatggggc cgcaggtgtc catttcatct acactagaga gggcaggcag    540

agtggtgagg cttttgttga acttggatca gaagatgatg taaaaatggc cctgaaaaaa    600

gacagggaaa gcatgggaca ccggtacatt gaggtgttca agtcccacag aaccgagatg    660

gattgggtgt tgaagcacag tggtcccaac agtgccgaca gcgccaacga tggcttcgtg    720

cggcttcgag gactcccatt tggatgcaca aaggaagaaa ttgttcagtt cttctcaggg    780

ttggaaattg tgccaaacgg gatcacattg cctgtggacc ccgaaggcaa gattacaggg    840

gaagcgttcg tgcagtttgc ctcgcaggag ttagctgaga aggctctagg gaaacacaag    900

gagaggatag ggcacaggta cattgaggtg tttaagagca gccaggagga agttaggtca    960

tactcagatc cccctctgaa gttcatgtcc gtgcagcggc cagggcccta tgaccggccc   1020

gggactgcca ggaggtacat tggcatcgtg aagcaggcag gcctggaaag gatgaggcct   1080

ggtgcctaca gcacaggcta cgggggctac gaggagtaca gtggcctcag tgatggctac   1140

ggcttcacca ccgacctgtt cgggagagac ctcagctact gtctctccgg aatgtatgac   1200

cacagatacg gcgacagtga gttcacagtg cagagcacca caggccactg tgtccacatg   1260

aggggcctgc cgtacaaagc gaccgagaac gacatttaca acttcttctc tcctctcaac   1320

cctgtgagag tccatattga gattggccca gatggaagag tgacgggtga agcagatgtt   1380

gagtttgcta ctcatgaaga agctgtggca gctatgtcca aagacagggc caatatgcag   1440

cacagatata tagaactctt cttgaattca acaacagggg ccagcaatgg ggcgtatagc   1500

agccaggtga tgcaaggcat gggggtgtct gctgcccagg ccacttacag tggcctggag   1560

agccagtcag tgagtggctg ttacggggcc ggctacagtg ggcagaacag catgggtggc   1620

tatgactagt tttgttagga acatttgagt tacttcaatc attttcacag gcagccaaca   1680

agcaattaag agcagttata atagaggaag ctgggggacc cattttgcac catgagtttg   1740

tgaaaaatct ggattaaaaa attacctctt cagtgttttc tcatgcaaaa ttttcttcta   1800

gcatgtgata atgagtaaac taaaactatt ttcagctttt ctcaattaac attttggtag   1860

tatacttcag agtgatgtta tctaagttta agtagtttaa gtatgttaaa tgtggatctt   1920

ttacaccaca tcacagtgaa cacactgggg agacgtgctt ttttggaaaa ctcaaaggtg   1980

ctagctccct gattcaaaga aatatttctc atgtttgttc attctagttt atattttcat   2040

ttaaaatcct ttaggttaag tttaagcttt ttaaaagtta gttttgagaa ttgagacaca   2100

atactaatac tgtaggaatt ggtgaggcct tgacttaaaa ctttctttgt actgtgattt   2160

ccttttgggt gtattttgct aagtgaaact tgttaaattt tttgttaact aaattttttt   2220

cttaaaataa agactttttc acaatgactg gcacagatta ctcagcaaaa gatagcaaaa   2280

cgggtggttg aagataattc attttaatcg taatgtattt tagtgtgaat ttaaaaattt   2340

catacatcaa atctatgatc tcccttatat tcttatgatg aggctaaata aaagtctaat   2400

aaaaatgtta aatatgtgaa tggtggaaat ggtgactagc agcacacatt ctgggaagca   2460

tcaaatagac acacggcccc agccacctgc aacttatgtg cactgttgta aaccattcag   2520

aattttcctg ctaggccctt gatgctggag tcacatctgt tgatagctgg agaactttag   2580

tttcaagtac tacattgtga aagcaattat tttgtttcta gtttttataa aatgctgatt   2640

taaactttta aaaaaaaaaa aaaaaaa                                       2667


<210>  971
<211>  3506
<212>  DNA
<213>  Homo sapiens

<400>  971
ttcctcccct ggactctttc tgagctcaga gccgccgcag ccgggacagg agggcaggct     60

ttctccaacc atcatgctgc ggagcatatt acctgtacgc cctggctccg ggagcggcag    120

tcgagtatcc tctggtcagg cggcgcgggc ggcgcctcag cggaagagcg ggcctctggg    180

ccgcagtgac caacccccgc ccctcacccc acgtggttgg aggtttccag aagcgctgcc    240

gccaccgcat cgcgcagctc tttgccgtcg gagcgcttgt ttgctgcctc gtactcctcc    300

atttatccgc catgataagt gccagccgag ctgcagcagc ccgtctcgtg ggcgccgcag    360

cctcccgggg ccctacggcc gcccgccacc aggatagctg gaatggcctt agtcatgagg    420

cttttagact tgtttcaagg cgggattatg catcagaagc aatcaaggga gcagttgttg    480

gtattgattt gggtactacc aactcctgcg tggcagttat ggaaggtaaa caagcaaagg    540

tgctggagaa tgccgaaggt gccagaacca ccccttcagt tgtggccttt acagcagatg    600

gtgagcgact tgttggaatg ccggccaagc gacaggctgt caccaaccca aacaatacat    660

tttatgctac caagcgtctc attggccggc gatatgatga tcctgaagta cagaaagaca    720

ttaaaaatgt tccctttaaa attgtccgtg cctccaatgg tgatgcctgg gttgaggctc    780

atgggaaatt gtattctccg agtcagattg gagcatttgt gttgatgaag atgaaagaga    840

ctgcagaaaa ttacttgggg cacacagcaa aaaatgctgt gatcacagtc ccagcttatt    900

tcaatgactc gcagagacag gccactaaag atgctggcca gatatctgga ctgaatgtgc    960

ttcgggtgat taatgagccc acagctgctg ctcttgccta tggtctagac aaatcagaag   1020

acaaagtcat tgctgtatat gatttaggtg gtggaacttt tgatatttct atcctggaaa   1080

ttcagaaagg agtatttgag gtgaaatcca caaatgggga taccttctta ggtggggaag   1140

actttgacca ggccttgcta cggcacattg tgaaggagtt caagagagag acaggggttg   1200

atttgactaa agacaacatg gcacttcaga gggtacggga agctgctgaa aaggctaaat   1260

gtgaactctc ctcatctgtg cagactgaca tcaatttgcc ctatcttaca atggattctt   1320

ctggacccaa gcatttgaat atgaagttga cccgtgctca atttgaaggg attgtcactg   1380

atctaatcag aaggactatc gctccatgcc aaaaagctat gcaagatgca gaagtcagca   1440

agagtgacat aggagaagtg attcttgtgg gtggcatgac taggatgccc aaggttcagc   1500

agactgtaca ggatcttttt ggcagagccc caagtaaagc tgtcaatcct gatgaggctg   1560

tggccattgg agctgccatt cagggaggtg tgttggccgg cgatgtcacg gatgtgctgc   1620

tccttgatgt cactcccctg tctctgggta ttgaaactct aggaggtgtc tttaccaaac   1680

ttattaatag gaataccact attccaacca agaagagcca ggtattctct actgccgctg   1740

atggtcaaac gcaagtggaa attaaagtgt gtcagggtga aagagagatg gctggagaca   1800

acaaactcct tggacagttt actttgattg gaattccacc agcccctcgt ggagttcctc   1860

agattgaagt tacatttgac attgatgcca atgggatagt acatgtttct gctaaagata   1920

aaggcacagg acgtgagcag cagattgtaa tccagtcttc tggtggatta agcaaagatg   1980

atattgaaaa tatggttaaa aatgcagaga aatatgctga agaagaccgg cgaaagaagg   2040

aacgagttga agcagttaat atggctgaag gaatcattca cgacacagaa accaagatgg   2100

aagaattcaa ggaccaatta cctgctgatg agtgcaacaa gctgaaagaa gagatttcca   2160

aaatgaggga gctcctggct agaaaagaca gcgaaacagg agaaaatatt agacaggcag   2220

catcctctct tcagcaggca tcactgaagc tgttcgaaat ggcatacaaa aagatggcat   2280

ctgagcgaga aggctctgga agttctggca ctggggaaca aaaggaagat caaaaggagg   2340

aaaaacagta ataatagcag aaattttgaa gccagaagga caacatatga agcttaggag   2400

tgaagagact tcctgagcag aaatgggcga acttcagtct ttttactgtg tttttgcagt   2460

attctatata taatttcctt aatttgtaaa tttagtgacc attagctagt gatcatttaa   2520

tggacagtga ttctaacagt ataaagttca caatattcta tgtccctagc ctgtcatttt   2580

tcagctgcat gtaaaaggag gtaggatgaa ttgatcatta taaagattta actattttat   2640

gctgaagtga ccatattttc aaggggtgaa accatctcgc acacagcaat gaaggtagtc   2700

atccatagac ttgaaatgag accacatatg gggatgagat ccttctagtt agcctagtac   2760

tgctgtactg gcctgtatgt acatggggtc cttcaactga ggccttgcaa gtcaagctgg   2820

ctgtgccatg tttgtagatg gggcagagga atctagaaca atgggaaact tagctattta   2880

tattaggtac agctattaaa acaaggtagg aatgaggcta gacctttaac ttccctaagg   2940

catacttttc tagctacctt ctgccctgtg tctggcacct acatccttga tgattgttct   3000

cttacccatt ctggaatttt ttttttttta aataaataca gaaagcatct tgatctcttg   3060

tttgtgaggg gtgatgccct gagatttagc ttcaagaata tgccatggct catgcttccc   3120

atatttccca aagagggaaa tacaggattt gctaacactg gttaaaaatg caaattcaag   3180

atttggaagg gctgttataa tgaaataatg agcagtatca gcatgtgcaa atcttgtttg   3240

aaggatttta ttttctcccc ttagaccttt ggtacattta gaatcttgaa agtttctaga   3300

tctctaacat gaaagtttct agatctctaa catgaaagtt tttagatctc taacatgaaa   3360

accaaggtgg ctattttcag gttgctttca gctccaagta gaaataacca gaattggctt   3420

acattaaaga aactgcatct agaaataagt cctaagatac tatttctatg gctcaaaaat   3480

aaaaggaacc cagatttctt tcccta                                        3506


<210>  972
<211>  1514
<212>  DNA
<213>  Homo sapiens

<400>  972
gatctggtaa acctgaagca aatatagaaa cctatagggc ctgacttcct acataaagta     60

aggagggtaa aaatggaggc tagaataagg gttaaaattt tgcttctaga acagagaaaa    120

tgattttttt catatatata tgaatatata ttatatatac acatatatac atatattcac    180

tatagtgtgt atacataaat atataatata tatattgtta gtgtagtgtg tgtctgatta    240

tttacatgca tatagtatat acacttatga ctttagtacc cagacgtttt tcatttgatt    300

aagcattcat ttgtattgac acagctgaag tttactggag tttagctgaa gtctaatgca    360

aaattaatag attgttgtca tcctcttaag gtcataggga gaacacacaa atgaaaacag    420

taaaagaaac tgaaagtaca gagaaatgtt cagaaaatga aaaccatgtg tttcctatta    480

aaagccatgc atacaagcaa tgtcttcaga aaacctaggg tccaaggtta agccatatcc    540

cagctcagta aagccaggag catcctcatt tcccaatggc cctcctgttc cctctactgg    600

cagccctagt gatgaccagc tatagccctg ttggatctct gggctgtgat ctgcctcaga    660

accatggcct acttagcagg aacaccttgg tgcttctgca ccaaatgagg agaatctccc    720

ctttcttgtg tctcaaggac agaagagact tcaggttccc ccaggagatg gtaaaaggga    780

gccagttgca gaaggcccat gtcatgtctg tcctccatga gatgctgcag cagatcttca    840

gcctcttcca cacagagcgc tcctctgctg cctggaacat gaccctccta gaccaactcc    900

acactggact tcatcagcaa ctgcaacacc tggagacctg cttgctgcag gtagtgggag    960

aaggagaatc tgctggggca attagcagcc ctgcactgac cttgaggagg tacttccagg   1020

gaatccgtgt ctacctgaaa gagaagaaat acagcgactg tgcctgggaa gttgtcagaa   1080

tggaaatcat gaaatccttg ttcttatcaa caaacatgca agaaagactg agaagtaaag   1140

atagagacct gggctcatct tgaaatgatt ctcattgatt aatttgccat ataacacttg   1200

cacatgtgac tctggtcaat tcaaaagact cttatttcgg ctttaatcac agaattgact   1260

gaattagttc tgcaaatact ttgtcggtat attaagccag tatatgttaa aaagacttag   1320

gttcaggggc atcagtccct aagatgttat ttatttttac tcatttattt attcttacat   1380

tttatcatat ttatactatt tatattctta tataacaaat gtttgccttt acattgtatt   1440

aagataacaa aacatgttca gctttccatt tggttaaata ttgtattttg ttatttatta   1500

aattattttc aaac                                                     1514


<210>  973
<211>  5905
<212>  DNA
<213>  Homo sapiens

<400>  973
ctcctcccgc accgccctgt cgcccaacgg cggcctcagg agtgatcggg cagcagtcgg     60

ccggccagcg gacggcagag cgggcggacg ggtaggcccg gcctgctctt cgcgaggagg    120

aagaaggtgg ccactctccc ggtccccaga acctccccag cccccgcagt ccgcccagac    180

cgtaaagggg gacgctgagg agccgcggac gctctccccg gtgccgccgc cgctgccgcc    240

gccatggctg ccatgatgga tcggaagtga gcattagggt taacggctgc cggcgccggc    300

tcttcaagtc ccggctcccc ggccgcctcc acccggggaa gcgcagcgcg gcgcagctga    360

ctgctgcctc tcacggccct cgcgaccaca agccctcagg tccggcgcgt tccctgcaag    420

actgagcggc ggggagtggc tcccggccgc cggccccggc tgcgagaaag atggcggacc    480

tggccgagtg caacatcaaa gtgatgtgtc gcttcagacc tctcaacgag tctgaagtga    540

accgcggcga caagtacatc gccaagtttc agggagaaga cacggtcgtg atcgcgtcca    600

agccttatgc atttgatcgg gtgttccagt caagcacatc tcaagagcaa gtgtataatg    660

actgtgcaaa gaagattgtt aaagatgtac ttgaaggata taatggaaca atatttgcat    720

atggacaaac atcctctggg aagacacaca caatggaggg taaacttcat gatccagaag    780

gcatgggaat tattccaaga atagtgcaag atatttttaa ttatatttac tccatggatg    840

aaaatttgga atttcatatt aaggtttcat attttgaaat atatttggat aagataaggg    900

acctgttaga tgtttcaaag accaaccttt cagttcatga agacaaaaac cgagttccct    960

atgtaaaggg gtgcacagag cgttttgtat gtagtccaga tgaagttatg gataccatag   1020

atgaaggaaa atccaacaga catgtagcag ttacaaatat gaatgaacat agctctagga   1080

gtcacagtat atttcttatt aatgtcaaac aagagaacac acaaacggaa caaaagctga   1140

gtggaaaact ttatctggtt gatttagctg gtagtgaaaa ggttagtaaa actggagctg   1200

aaggtgctgt gctggatgaa gctaaaaaca tcaacaagtc actttctgct cttggaaatg   1260

ttatttctgc tttggctgag ggtagtacat atgttccata tcgagatagt aaaatgacaa   1320

gaatccttca agattcatta ggtggcaact gtagaaccac tattgtaatt tgctgctctc   1380

catcatcata caatgagtct gaaacaaaat ctacactctt atttggccaa agggccaaaa   1440

caattaagaa cacagtttgt gtcaatgtgg agttaactgc agaacagtgg aaaaagaagt   1500

atgaaaaaga aaaagaaaaa aataagatcc tgcggaacac tattcagtgg cttgaaaatg   1560

agctcaacag atggcgtaat ggggagacgg tgcctattga tgaacagttt gacaaagaga   1620

aagccaactt ggaagctttc acagtggata aagatattac tcttaccaat gataaaccag   1680

caaccgcaat tggagttata ggaaatttta ctgatgctga aagaagaaag tgtgaagaag   1740

aaattgctaa attatacaaa cagcttgatg acaaggatga agaaattaac cagcaaagtc   1800

aactggtaga gaaactgaag acgcaaatgt tggatcagga ggagcttttg gcatctacca   1860

gaagggatca agacaatatg caagctgagc tgaatcgcct tcaagcagaa aatgatgcct   1920

ctaaagaaga agtgaaagaa gttttacagg ccctagaaga acttgctgtc aattatgatc   1980

agaagtctca ggaagttgaa gacaaaacta aggaatatga attgcttagt gatgaattga   2040

atcagaaatc ggcaacttta gcgagtatag atgctgagct tcagaaactt aaggaaatga   2100

ccaaccacca gaaaaaacga gcagctgaga tgatggcatc tttactaaaa gaccttgcag   2160

aaataggaat tgctgtggga aataatgatg taaagcagcc tgagggaact ggcatgatag   2220

atgaagagtt cactgttgca agactctaca ttagcaaaat gaagtcagaa gtaaaaacca   2280

tggtgaaacg ttgcaagcag ttagaaagca cacaaactga gagcaacaaa aaaatggaag   2340

aaaatgaaaa ggagttagca gcatgtcagc ttcgtatctc tcaacatgaa gccaaaatca   2400

agtcattgac tgaatacctt caaaatgtgg aacaaaagaa aagacagttg gaggaatctg   2460

tcgatgccct cagtgaagaa ctagtccagc ttcgagcaca agagaaagtc catgaaatgg   2520

aaaaggagca cttaaataag gttcagactg caaatgaagt taagcaagct gttgaacagc   2580

agatccagag ccatagagaa actcatcaaa aacagatcag tagtttgaga gatgaagtag   2640

aagcaaaagc aaaacttatt actgatcttc aagaccaaaa ccagaaaatg atgttagagc   2700

aggaacgtct aagagtagaa catgagaagt tgaaagccac agatcaggaa aagagcagaa   2760

aactacatga acttacggtt atgcaagata gacgagaaca agcaagacaa gacttgaagg   2820

gtttggaaga gacagtggca aaagaacttc agactttaca caacctgcgc aaactctttg   2880

ttcaggacct ggctacaaga gttaaaaaga gtgctgagat tgattctgat gacaccggag   2940

gcagcgctgc tcagaagcaa aaaatctcct ttcttgaaaa taatcttgaa cagctcacta   3000

aagtgcacaa acagttggta cgtgataatg cagatctccg ctgtgaactt cctaagttgg   3060

aaaagcgact tcgagctaca gctgagagag tgaaagcttt ggaatcagca ctgaaagaag   3120

ctaaagaaaa tgcatctcgt gatcgcaaac gctatcagca agaagtagat cgcataaagg   3180

aagcagtcag gtcaaagaat atggccagaa gagggcattc tgcacagatt gctaaaccta   3240

ttcgtcccgg gcaacatcca gcagcttctc caactcaccc aagtgcaatt cgtggaggag   3300

gtgcatttgt tcagaacagc cagccagtgg cagtgcgagg tggaggaggc aaacaagtgt   3360

aatcgtttat acatacccac aggtgttaaa aagtaatcga agtacgaaga ggacatggta   3420

tcaagcagtc attcaatgac tataacctct actcccttgg gattgtagaa ttataacttt   3480

taaaaaaaat gtataaatta tacctggcct gtacagctgt ttcctaccta ctcttcttgt   3540

aaactctgct gcttcccaac acaactagag tgcaattttg gcatcttagg agggaaaaag   3600

gacagtttac aactgtggcc ctatttatta cacagtttgt ctatcgtgtc ttaaatttag   3660

tctttactgt gccaagctaa ctgtacctta taggactgta ctttttgtat tttttgtgta   3720

tgtttatttt ttaatctcag tttaaattac ctagctgcta ctgcttcttg tttttctttt   3780

cctattaaaa cgtcttcctt tttttttctt aagagaaaat ggaacattta ggttaaatgt   3840

ctttaaattt taccacttaa caacactaca tgcccataaa atatatccag tcagtactgt   3900

attttaaaat cccttgaaat gatgatatca gggttaaaat tacttgtatt gtttctgaag   3960

tttgctcctg aaaactactg tttgagcact gaaacgttac aaatgcctaa taggcatttg   4020

agactgagca aggctacttg ttatctcatg aaatgcctgt tgccgagtta ttttgaatag   4080

aaatatttta aagtatcaaa agcagatctt agtttaaggg agtttggaaa aggaattata   4140

tttctctttt tcctgattct gtactcaaca agtcttgatg gaattaaaat actctgcttt   4200

attctggtga gcctgctagc taatataagt attggacagg taataatttg tcatctttaa   4260

tattagtaaa atgaattaag atattatagg attaaacata attttatacg gttagtactt   4320

tattggccga cctaaattta tagcgtgtgg aaattgagaa aaatgaagaa acaggacaga   4380

tatatgatga attaaaaata tatataggtc aattttggtc tgaaatccct gaggtgtttt   4440

taacctgcta cactaatttg tacactaatt tatttcttta gtctagaaat agtaaattgt   4500

ttgcaagtca ctaataatca ttagataaat tattttcttg gccatagccg ataattttgt   4560

aatcagtact aagtgtatac gtatttttgc cactttttcc tcagatgatt aaagtaagtc   4620

aacagcttat tttaggaaac tgtaaaagta atagggaaag agatttcact atttgcttca   4680

tcagtggtag gggggcggtg actgcaactg tgttagcaga aattcacaga gaatggggat   4740

ttaaggttag cagagaaact tggaaagttc tgtgttagga tcttgctggc agaattaact   4800

ttttgcaaaa gttttataca cagatatttg tattaaattt ggagccatag tcagaagact   4860

cagatcataa ttggcttatt tttctatttc cgtaactatt gtaatttcca cttttgtaat   4920

aattttgatt taaaatataa atttatttat ttattttttt aatagtcaaa aatctttgct   4980

gttgtagtct gcaacctcta aaatgattgt gttgctttta ggattgatca gaagaaacac   5040

tccaaaaatt gagatgaaat gttggtgcag ccagttataa gtaatatagt taacaagcaa   5100

aaaaagtgct gccacctttt atgatgattt tctaaatgga gaaacatttg gctgcatcca   5160

catagacctt tatgttttgt tttcagttga aaacttgcct cctttggcaa cattcgtaaa   5220

tgaagcagaa tttttttttc tcttttttcc aaatatgtta gttttgttct tgtaagatgt   5280

atcatgggta ttggtgctgt gtaatgaaca acgaatttta attagcatgt ggttcagaat   5340

atacaatgtt aggtttttaa aaagtatctt gatggttctt ttctatttat aatttcagac   5400

tttcataaag tgtaccaaga atttcataaa tttgttttca gtgaactgct ttttgctatg   5460

gtaggtcatt aaacacagca cttactctta aaaatgaaaa tttctgatca tctaggatat   5520

tgacacattt caatttgcag tgtctttttg actggatata ttaacgttcc tctgaatggc   5580

attgatagat ggttcagaag agaaactcaa tgaaataaag agaatattta ttcatggcga   5640

ttaattaaat tatttgccta acttaagaaa actactgtgc gtaactctca gtttgtgctt   5700

aactccattt gacatgaggt gacagaagag agtctgagtc tacctgtgga atatgttggt   5760

ttattttcag tgcttgaaga tacattcaca aatacttggt ttgggaagac accgtttaat   5820

tttaagttaa cttgcatgtt gtaaatgcgt tttatgttta aataaagagg aaaatttttt   5880

gaaatgtaaa aaaaaaaaaa aaaaa                                         5905


<210>  974
<211>  2445
<212>  DNA
<213>  Homo sapiens

<400>  974
cagagaccct tgacgggcat actgtttcct ccgggctcct gcctcatgag gggagaggtg     60

cggcttggct ccaatggcgc cattttgcgg tacggaagct acacagcaac acgtatagga    120

gactctcccc gagatcttct agggagtgac ccatctattt ttgtttggga agaggaaact    180

ccgaaatggg atcgcggaag acttaaaggg ccaggctgat ttttttttcc tactgcaggt    240

ctctgaggct gtggttgcta cagggtcacc acgagcttgg cttacttgtc tcatccttcc    300

cttgcctggt atcattttct cagttctccc aaaagccatg tcccggccct tgctcatcac    360

cttcacccca gccactgacc ccagcgacct ctggaaggat gggcagcagc agccacagcc    420

cgagaagcca gagtccaccc tggatggggc tgcagcccga gctttctatg aggccctgat    480

tggggatgag agcagcgctc ctgactccca gagatctcag actgaacctg ccagagaaag    540

aaagagaaag aaaagaagaa taatgaaggc accagcagca gaagcagtgg cagaaggagc    600

atcaggaaga catggacaag ggagatccct tgaggctgag gataagatga ctcaccggat    660

actgagggca gcccaggagg gggacctgcc agaacttagg agactgctgg aaccgcatga    720

ggcaggagga gctgggggga atatcaacgc ccgggatgcc ttctggtgga ccccactgat    780

gtgtgctgct cgagcgggcc agggggcagc tgtgagctat ctcctgggcc gtggggctgc    840

ctgggtgggg gtctgtgagc tgagtggcag ggatgcggct cagctcgctg aagaagctgg    900

cttccctgag gtagcccgca tggtcaggga gagccatgga gagacaagga gcccggaaaa    960

ccggtctcct actccctccc tccagtactg cgagaactgt gacacccact tccaagattc   1020

caaccaccgc acatccactg ctcacctgct gtcactgtcg cagggtcctc agcctcccaa   1080

ccttccactt ggggtgccca tctccagccc gggcttcaaa ctgctgctga gggggggctg   1140

ggagccagga atggggctgg gaccccgggg tgagggccgt gccaatccca tccccactgt   1200

cctcaagagg gaccaggaag gactaggcta cagatcagca ccccagcccc gagtgacaca   1260

tttcccagct tgggataccc gagctgtggc tgggagggag agaccccctc gggtggccac   1320

actgagctgg agggaggaga gaaggaggga ggagaaagac agggcttggg agcgggatct   1380

aaggacttac atgaacctcg agttctgact ttggtaaagt ctgaccctag tctgctgctg   1440

aagtctgaac ttgggcctct gacctgggcc ctttgacttc cccttcctgg gatctgctca   1500

gatgcagatc ctgaagtttt tggtcaatag gctctgtctt cgtgagagac gggctgagag   1560

tcagaaataa atcaaccatt tgtggtttat tcacttttct ggaagctatt ttgaggaagc   1620

caaacagaag cctgggagcc acatgcaagt cccacctgag tcagaagggg cagcctctcc   1680

aggtggcatg ataaggtcac ctccctgcca atctgggttc actttcaggt cccagaccct   1740

cctgggagtc ccccacctat tctttcaacc cccctggacc aagaattgcc cagcttcgtg   1800

caagtctcac ttcccccagg aggagttccc tgactacagc caattcactg atttcacaaa   1860

cataagtcca tatactatgt gccaagaata caggtaaaga cattcccaac cctcaaagag   1920

ttcacagctg gagagggaaa gtgccatgtt atcaattttt ttcttttttt tttgagatgc   1980

agtttcgctc tcattgccca ggctggagtg caatggcatg atctcggctc accacaacct   2040

ctgccccccg agttcaaggg attctcctgc ctcagcctcc ccagtagctg ggattacagg   2100

catgccccac cacgcccagc taattttgta tttttagtag agacggggtt tctccatgtt   2160

ggccaagctg gtcttgaact cccgacctca ggtgatccgc cggcctcggc ttcccaaagt   2220

gctggggttg caggcatgag ccaccactcc cggcccatgt tatcaaatat tataatgcag   2280

ggtgataagg gaagtcaagg cctctagaga tgagaatggg tagggttttg ctggaagagg   2340

ccagtgtgat aggaaggccc acgattatca agcttgtaca cttagttgaa ctgggaccag   2400

aactctagcc cccaaatcta aactttaaac ttctttgttc caccc                   2445


<210>  975
<211>  534
<212>  DNA
<213>  Homo sapiens

<400>  975
cgactttccc gatcgccagg caggagtttc tctcggtgac tactatcgct gtcatgtctg     60

gtcgtggcaa gcaaggaggc aaggcccgcg ccaaggccaa gtcgcgctcg tcccgcgctg    120

gccttcagtt cccggtaggg cgagtgcatc gcttgctgcg caaaggcaac tacgcggagc    180

gagtgggggc cggcgcgccc gtctacatgg ctgcggtcct cgagtatctg accgccgaga    240

tcctggagct ggcgggcaac gcggctcggg acaacaagaa gacgcgcatc atccctcgtc    300

acctccagct ggccatccgc aacgacgagg aactgaacaa gctgctgggc aaagtcacca    360

tcgcccaggg cggcgtcttg cctaacatcc aggccgtact gctccctaag aagacggaga    420

gtcaccacaa ggcaaagggc aagtgaggct gacgtccggc ccaagtgggc ccagcccggc    480

ccgcgtctcg aaggggcacc tgtgaactca aaaggctctt ttcagagcca ccca          534


<210>  976
<211>  1550
<212>  DNA
<213>  Homo sapiens

<400>  976
ggtgggccca cacaagcggc gcaccgttaa gatggcggct gggctgcgga aacgcggccg     60

gtccggttcc gcggcccagg cagagggact ctgcaagcaa tggctgcagc gcgcctggca    120

agagcggcgc ctgctgctgc gggagccgcg ctacacgctg ctggtggccg cctgcctctg    180

cctggcggag gtgggcatca ccttctgggt cattcacagg gtggcataca cagagattga    240

ctggaaggcc tacatggccg aggtagaagg cgtcatcaat ggtacctatg actataccca    300

actgcagggt gacaccggac cacttgtgta cccagctggt ttcgtgtaca tctttatggg    360

gttgtactat gccaccagcc gaggcactga catccgcatg gcccagaaca tctttgctgt    420

gctctacctg gctaccttgc tgcttgtctt cttgatctat caccagacct gcaaggtacc    480

tcccttcgtc tttttcttca tgtgctgcgc ctcttaccgt gtccactcca tctttgtgct    540

gcggctcttc aatgacccag tggccatggt gctgctcttc ctcagtatca acctcctgct    600

ggcccagcgc tggggctggg gttgctgctt tttcagcctg gcagtctctg tgaagatgaa    660

tgtgctgctc ttcgcccctg ggttactgtt tcttctcctc acacagtttg gcttccgtgg    720

ggccctcccc aagctgggaa tctgtgctgg ccttcaggtg gtgctggggc tgcccttcct    780

gctggagaac cccagcggct acctgtcccg ctcctttgac cttggccgcc agtttctgtt    840

ccactggaca gtgaactggc gcttcctccc agaggcgctc ttcctgcatc gagccttcca    900

cctggccctg ttgactgccc acctcaccct gctcctgctg tttgccctct gcaggtggca    960

caggacaggg gaaagtatct tgtcgctgct gagggatccc tccaaaagga aggttccacc   1020

ccagcccctt acacccaacc agatcgtttc taccctcttc acctccaact tcattggcat   1080

ctgcttcagc cgctccctcc actaccagtt ctacgtctgg tatttccaca cactgcccta   1140

cctcctgtgg gccatgcctg cacgctggct cacacacctg ctcaggttgt tggtgctggg   1200

gctcatcgag ctctcctgga acacataccc ttccacatcc tgcagctctg ctgccctgca   1260

catatgccat gccgtcatcc tgctgcagct ctggctgggc ccgcagcctt tccccaagag   1320

cacccaacac agcaagaaag cccactgaag tccacccctt tccctcagga cctgagtcta   1380

ccctcaggac ctggggttgg ttggactctg cccttccaaa taaaccttgc taagtccaac   1440

tctgtgcaac ctacatggag gtgggggcag ccgatgcctg gtccaggctg tgagggacac   1500

gtatggagca gataaagaat tcactcaagc agtaaaaaaa aaaaaaaaaa              1550


<210>  977
<211>  4625
<212>  DNA
<213>  Homo sapiens

<400>  977
tgaggagggc ccggcctgcg agagcctcag tgggagccgg ctcagccctc ggccaccatg     60

tcggcgccgt cggaggagga ggagtacgcg cggctggtga tggaggcgca gccggagtgg    120

ctgcgcgccg aggtgaagcg gctgtcccac gagctggccg agaccacgcg tgagaagatc    180

caggcggccg agtacgggct ggcggtgctc gaggagaagc accagctcaa gctgcagttc    240

gaggagctcg aggtggacta tgaggctatc cgcagcgaga tggagcagct caaggaggcc    300

tttggacaag cacacacaaa ccacaagaag gtggctgctg acggagagag ccgggaggag    360

agcctgatcc aggagtcggc ctccaaggag cagtactacg tgcggaaggt gctagagctg    420

cagacggagc tgaagcagtt gcgcaatgtc ctcaccaaca cgcagtcgga gaatgagcgc    480

ctggcctctg tggcccagga gctgaaggag atcaaccaga atgtggagat ccagcgtggc    540

cgcctgcggg atgacatcaa ggagtacaaa ttccgggaag ctcgtctgct gcaggactac    600

tcggaactgg aggaggagaa catcagcctg cagaagcaag tgtctgtgct cagacagaac    660

caggtggagt ttgagggcct caagcatgag atcaagcgtc tggaggagga gaccgagtac    720

ctcaacagcc agctggagga tgccatccgc ctcaaggaga tctcagagcg gcagctggag    780

gaggcgctgg agaccctgaa gacggagcgc gaacagaaga acagcctgcg caaggagctg    840

tcacactaca tgagcatcaa tgactccttc tacaccagcc acctgcatgt ctcgctggat    900

ggcctcaagt tcagtgacga tgctgccgag cccaacaacg atgccgaggc cctggtcaat    960

ggctttgagc acggcggcct ggccaagctg ccactggaca acaagacctc cacgcccaag   1020

aaggagggcc tcgcaccgcc ctcccccagc ctcgtctccg acctactcag tgagctcaac   1080

atctctgaga tccagaagct gaagcagcag ctgatgcaga tggagcggga aaaggcgggc   1140

ctgctggcaa cgctgcagga cacacagaag cagctggagc acacgcgggg ctccctgtca   1200

gaacagcagg agaaggtgac ccgcctcaca gagaatctga gtgccctgcg gcgcctgcag   1260

gccagcaagg agcggcagac agccctggac aacgagaagg accgtgacag ccatgaggat   1320

ggggactact acgaggtgga catcaacggg cctgagatct tggcctgcaa gtaccatgtg   1380

gctgtggctg aggctggcga gctccgcgag cagctcaagg cactgcgcag cacgcacgag   1440

gctcgtgagg cccagcacgc cgaggagaag ggccgctatg aggctgaggg ccaggcactc   1500

acggagaagg tctccctgct agagaaggcc agccgccagg accgcgagct gctggcccgg   1560

ctggagaagg agctaaagaa ggtgagcgac gtcgccggcg agacacaggg cagcctgagt   1620

gtggcccagg atgagctggt gaccttcagt gaggagctgg ccaatctcta ccaccacgtg   1680

tgcatgtgca acaatgagac acccaaccgt gtcatgctgg actactaccg cgagggccag   1740

ggcggggccg gccgcaccag tcccgggggc cgcaccagcc ccgaggcgcg tggccggcgc   1800

tcacccatcc tcctacccaa ggggctgctg gctcctgagg cgggccgagc agatggtggg   1860

acgggggaca gcagcccctc gcctggctcc tcactgccat cacccctgag tgacccacgc   1920

cgggagccca tgaacatcta caacctgatc gctatcatcc gtgaccagat caagcacctg   1980

caggcagccg tggaccgcac cacggagctg tcacgccagc gcattgcctc tcaggagctg   2040

ggccccgccg tggacaagga caaggaagcg cttatggagg agatcctcaa gctgaagtcg   2100

ctgctcagca ccaagcggga gcagatcacc acgctgcgca ctgtgctcaa ggccaacaag   2160

cagacggccg aggtggccct tgccaacctg aagagcaagt atgagaatga gaaggccatg   2220

gttaccgaga ccatgatgaa gctgcgcaat gagctcaagg ccctcaagga ggacgcagcc   2280

accttctcct cgctgcgtgc tatgtttgcc accaggtgtg acgagtacat tacacagctg   2340

gatgagatgc agcggcagct ggcggctgct gaggacgaga agaagacgct gaactcgctg   2400

ctgcgcatgg ccatccagca gaagctggcg ctgacccagc ggctggagct gctcgagctg   2460

gaccatgagc agacccggcg tggccgtgcc aaagccgccc cgaagaccaa gccagccaca   2520

ccgagcctgt agagtagctg ccaggaggac ttggccaccc ggccctgtca cactgcagcc   2580

ccttcccctt ccctctcgtg gcccacaagg aggaaggaag ggcaacctaa aagcccactt   2640

agaaactttt tggatatgcc actgcaattc ttttcaaaat agcattcccc aggtttttaa   2700

tgggaggaaa aaaagcttta atgttgagca tgctgcgagc tgctgcgtgg aaaggcctct   2760

gtatgggccg aagacccttc ttccctggct gccaggctcg ccaggagccc actggaaacg   2820

cccaccacgg gggctccttg ttacacatgt tcttttttta tccgatcaac ctgtgcactt   2880

ttgatatttt gatattatat ttgcttcctt aattcctcgc gtagagacgg tctcaggtgc   2940

cgtggtctat gctcgtggtc ctgtagctgt ccgcctcagc tcccaccgtg tttgtctggt   3000

gtcagcacga ggcagagctg tgtgctccat agcgtgtagc tttagactcg gagatgagtg   3060

ctttgaccca gcgaggagct cagctaagtg tatccacgct gtggttcagc agcctttaga   3120

tcatacggca ttgtggttca tgtttgaaat tacagatttt aaatgccatg ttcattaaga   3180

aatccagggt attcagattc tggggttttt catattgtat tattattatt cttaggaata   3240

gttcaatgta acaagaagaa aacttgacct ttgctctggt taaaacagta ataggcactt   3300

gaaaaaaaaa gataaattat tgaatgagta gtattaccta caaattccag aattttctgg   3360

gttttaggac gttgtgaagc atgactgatt aacagaattt tatacaactg taccaataaa   3420

attccaaatt ggaattgttt tgttactctg gttgttgtgc caaattgtgg tacacttaga   3480

aaattctaca gtcgtcgatt tttagggtgt tctctttcaa cacctttttg ttagtaatca   3540

ttgccagtag tgccttcatc agttaaggga ggtgtcccag cacagatcat tctcaaaagc   3600

gagcagggaa gagctagtgg gcatgctgaa ggccagcgtg gacagcaggt gaggcaggtg   3660

ctcctcacac ccagacctgg gcatcttcat tgagggaaag aaaacagtca ttgtgcaaaa   3720

ttctgttagt cagtgattct ttacttgcaa attcaggggc ttagaaaatg aaagcaaaca   3780

caaaaccttg agtgtgcttt gggaaccaaa tggaccttct gggacaagct gagcaagctg   3840

tatgaacgcc acgtttgtga agagctgagg gtatcaggag ggccgacgct gtgttggcat   3900

gcgcagtagg ggatgagggt tagccatagt attctttgca aatgtgaaag cgagacatta   3960

tatcttctct tgcttggtgt aactaatcac tgttaatttc aggaaacaga actcattaaa   4020

actccttagc aaaccaggtc tacatcctgt tttgtttgct gagtgaggtt agtgggagtg   4080

gtcaaattgg tactcttgga ggaagaaaaa ctgtccttcc ttctccaaaa aaggaaaaat   4140

tataataata taaatgacaa aaataaaaga attctgtttc ctggaataag catttcttat   4200

tcctagttgt agggactcct atttttacct tccgttacag tgttgattca taagaaatat   4260

tgttacattt gagataactt catctgtatg gggtatttat ttgcaatgat gtctgagtac   4320

tgtatttttt ctgtgcatta ccttagtgtc agaatgttgg tctttatttt aaagtcatat   4380

gcatgttctc ctgccaagga acctttacac agacccaaac aaaaaaataa taatcaaatg   4440

ccttcaattt ctgagaaaat gaggcagagc atggaaaagg aataggaagg agaaattaat   4500

tgagattttc aggacacaga catatgatgt gaatgcctac aaagccagtg cgcataggaa   4560

cagtgggcct gggtaaagag tcacattggt aggaccaata aagaataata aaaagacaaa   4620

gcaca                                                               4625


<210>  978
<211>  7972
<212>  DNA
<213>  Homo sapiens

<400>  978
atttgaagtc ctcgttccac gccttctcat catcctgaac accgagctct gggactccgg     60

cggagaatct aaacgtaaag catcacccac ggtcgtgaac tgtaggctct cctggcatcc    120

gggatcttat tctggccttg gcggagttgg ggatggtgtc gcctagcagc cgctgccgct    180

ttggcttgct cgggaccatt tggctggacc cagagtccgc gtggaaccgc gatagggatc    240

tgtcagggcc cgcggccggg tccagcttgg tggttgcggt agtgagaggc ctccgctggt    300

tgccaggctt ggtctagagg tggagcacag tgaaagaatt caagatgcca cctaatataa    360

actggaaaga aataatgaaa gttgacccag atgacctgcc ccgtcaagaa gaactggcag    420

ataatttatt gatttcctta tccaaggtgg aagtaaatga gctaaaaagt gaaaagcaag    480

aaaatgtgat acaccttttc agaattactc agtcactaat gaagatgaaa gctcaagaag    540

tggagctggc tttggaagaa gtagaaaaag ctggagaaga acaagcaaaa tttgaaaatc    600

aattaaaaac taaagtaatg aaactggaaa atgaactgga gatggctcag cagtctgcag    660

gtggacgaga tactcggttt ttacgtaatg aaatttgcca acttgaaaaa caattagaac    720

aaaaagatag agaattggag gacatggaaa aggagttgga gaaagagaag aaagttaatg    780

agcaattggc tcttcgaaat gaggaggcag aaaatgaaaa cagcaaatta agaagagaga    840

acaaacgtct aaagaaaaag aatgaacaac tttgtcagga tattattgac taccagaaac    900

aaatagattc acagaaagaa acacttttat caagaagagg ggaagacagt gactaccgat    960

cacagttgtc taaaaaaaac tatgagctta tccaatatct tgatgaaatt cagactttaa   1020

cagaagctaa tgagaaaatt gaagttcaga atcaagaaat gagaaaaaat ttagaagagt   1080

ctgtacagga aatggagaag atgactgatg aatataatag aatgaaagct attgtgcatc   1140

agacagataa tgtaatagat cagttaaaaa aagaaaacga tcattatcaa cttcaagtgc   1200

aggagcttac agatcttctg aaatcaaaaa atgaagaaga tgatccaatt atggtagctg   1260

tcaatgcaaa agtagaagaa tggaagctaa ttttgtcttc taaagatgat gaaattattg   1320

agtatcagca aatgttacat aacctaaggg agaaacttaa gaatgctcag cttgatgctg   1380

ataaaagtaa tgttatggct ctacagcagg gtatacagga acgagacagt caaattaaga   1440

tgctcaccga acaagtagaa caatatacaa aagaaatgga aaagaatact tgtattattg   1500

aagatttgaa aaatgagctc caaagaaaca aaggtgcttc aaccctttct caacagactc   1560

atatgaaaat tcagtcaacg ttagacattt taaaagagaa aactaaagag gctgagagaa   1620

cagctgaact ggctgaggct gatgctaggg aaaaggataa agaattagtt gaggctctga   1680

agaggttaaa agattatgaa tcgggagtat atggtttaga agatgctgtc gttgaaataa   1740

agaattgtaa aaaccaaatt aaaataagag atcgagagat tgaaatatta acaaaggaaa   1800

tcaataaact tgaattgaag atcagtgatt tccttgatga aaatgaggca cttagagagc   1860

gtgtgggcct tgaaccaaag acaatgattg atttaactga atttagaaat agcaaacact   1920

taaaacagca gcagtacaga gctgaaaacc agattctttt gaaagagatt gaaagtctag   1980

aggaagaacg acttgatctg aaaaaaaaaa ttcgtcaaat ggctcaagaa agaggaaaaa   2040

gaagtgcaac ttcaggatta accactgagg acctgaacct aactgaaaac atttctcaag   2100

gagatagaat aagtgaaaga aaattggatt tattgagcct caaaaatatg agtgaagcac   2160

aatcaaagaa tgaatttctt tcaagagaac taattgaaaa agaaagagat ttagaaagga   2220

gtaggacagt gatagccaaa tttcagaata aattaaaaga attagttgaa gaaaataagc   2280

aacttgaaga aggtatgaaa gaaatattgc aagcaattaa ggaaatgcag aaagatcctg   2340

atgttaaagg aggagaaaca tctctaatta tccctagcct tgaaagacta gttaatgcta   2400

tagaatcaaa gaatgcagaa ggaatctttg atgcgagtct gcatttgaaa gcccaagttg   2460

atcagcttac cggaagaaat gaagaattaa gacaggagct cagggaatct cggaaagagg   2520

ctataaatta ttcacagcag ttggcaaaag ctaatttaaa gatagaccat cttgaaaaag   2580

aaactagtct tttacgacaa tcagaaggat cgaatgttgt ttttaaagga attgacttac   2640

ctgatgggat agcaccatct agtgccagta tcattaattc tcagaatgaa tatttaatac   2700

atttgttaca ggaactagaa aataaagaaa aaaagttaaa gaatttagaa gattctcttg   2760

aagattacaa cagaaaattt gctgtaattc gtcatcaaca aagtttgttg tataaagaat   2820

acctaagtga aaaggagacc tggaaaacag aatctaaaac aataaaagag gaaaagagaa   2880

aacttgagga tcaagtccaa caagatgcta taaaagtaaa agaatataat aatttgctca   2940

atgctcttca gatggattcg gatgaaatga aaaaaatact tgcagaaaat agtaggaaaa   3000

ttactgtttt gcaagtgaat gaaaaatcac ttataaggca atatacaacc ttagtagaat   3060

tggagcgaca acttagaaaa gaaaatgaga agcaaaagaa tgaattgttg tcaatggagg   3120

ctgaagtttg tgaaaaaatt gggtgtttgc aaagatttaa ggaaatggcc attttcaaga   3180

ttgcagctct ccaaaaagtt gtagataata gtgtttcttt gtctgaacta gaactggcta   3240

ataaacagta caatgaactg actgctaagt acagggacat cttgcaaaaa gataatatgc   3300

ttgttcaaag aacaagtaac ttggaacacc tggagtgtga aaacatctcc ttaaaagaac   3360

aagtggagtc tataaataaa gaactggaga ttaccaagga aaaacttcac actattgaac   3420

aagcctggga acaggaaact aaattaggta atgaatctag catggataag gcaaagaaat   3480

caataaccaa cagtgacatt gtttccattt caaaaaaaat aactatgctg gaaatgaagg   3540

aattaaatga aaggcagcgg gctgaacatt gtcaaaaaat gtatgaacac ttacggactt   3600

cgttaaagca aatggaggaa cgtaattttg aattggaaac caaatttgct gagcttacca   3660

aaatcaattt ggatgcacag aaggtggaac agatgttaag agatgaatta gctgatagtg   3720

tgagcaaggc agtaagtgat gctgataggc aacggattct agaattagag aagaatgaaa   3780

tggaactaaa agttgaagtg tcaaaactga gagagatttc tgatattgcc agaagacaag   3840

ttgaaatttt gaatgcacaa caacaatcta gggacaagga agtagagtcc ctcagaatgc   3900

aactgctaga ctatcaggca cagtctgatg aaaagtcgct cattgccaag ttgcaccaac   3960

ataatgtctc tcttcaactg agtgaggcta ctgctcttgg taagttggag tcaattacat   4020

ctaaactgca gaagatggag gcctacaact tgcgcttaga gcagaaactt gatgaaaaag   4080

aacaggctct ctattatgct cgtttggagg gaagaaacag agcaaaacat ctgcgccaaa   4140

caattcagtc tctacgacga cagtttagtg gagctttacc cttggcacaa caggaaaagt   4200

tctccaaaac aatgattcaa ctacaaaatg acaaacttaa gataatgcaa gaaatgaaaa   4260

attctcaaca agaacataga aatatggaga acaaaacatt ggagatggaa ttaaaattaa   4320

agggcctgga agagttaata agcactttaa aggataccaa aggagcccaa aaggtaatca   4380

actggcatat gaaaatagaa gaacttcgtc ttcaagaact taaactaaat cgggaattag   4440

tcaaggataa agaagaaata aaatatttga ataacataat ttctgaatat gaacgtacaa   4500

tcagcagtct tgaagaagaa attgtgcaac agaacaagtt tcatgaagaa agacaaatgg   4560

cctgggatca aagagaagtt gacctggaac gccaactaga catttttgac cgtcagcaaa   4620

atgaaatact aaatgcggca caaaagtttg aagaagctac aggatcaatc cctgacccta   4680

gtttgcccct tccaaatcaa cttgagatcg ctctaaggaa aattaaggag aacattcgaa   4740

taattctaga aacacgggca acttgcaaat cactagaaga gaaactaaaa gagaaagaat   4800

ctgctttaag gttagcagaa caaaatatac tgtcaagaga caaagtaatc aatgaactga   4860

ggcttcgatt gcctgccact gcagaaagag aaaagctcat agctgagcta ggcagaaaag   4920

agatggaacc aaaatctcac cacacattga aaattgctca tcaaaccatt gcaaacatgc   4980

aagcaaggtt aaatcaaaaa gaagaagtat taaagaagta tcaacgtctt ctagaaaaag   5040

ccagagagga gcaaagagaa attgtgaaga aacatgagga agaccttcat attcttcatc   5100

acagattaga actacaggct gatagttcac taaataaatt caaacaaacg gcttgggatt   5160

taatgaaaca gtctcccact ccagttccta ccaacaagca ttttattcgt ctggctgaga   5220

tggaacagac agtagcagaa caagatgact ctctttcctc actcttggtc aaactaaaga   5280

aagtatcaca agatttggag agacaaagag aaatcactga attaaaagta aaagaatttg   5340

aaaatatcaa attacagctt caagaaaacc atgaagatga agtgaaaaaa gtaaaagcgg   5400

aagtagagga tttaaagtat cttctggacc agtcacaaaa ggagtcacag tgtttaaaat   5460

ctgaacttca ggctcaaaaa gaagcaaatt caagagctcc aacaactaca atgagaaatc   5520

tagtagaacg gctaaagagc caattagcct tgaaggagaa acaacagaaa gcacttagtc   5580

gggcactttt agaactccgg gcagaaatga cagcagctgc tgaagaacgt attatttctg   5640

caacttctca aaaagaggcc catctcaatg ttcaacaaat cgttgatcga catactagag   5700

agctaaagac acaagttgaa gatttaaatg aaaatctttt aaaattgaaa gaagcactta   5760

aaacaagtaa aaacagagaa aactcactaa ctgataattt gaatgactta aataatgaac   5820

tgcaaaagaa acaaaaagcc tataataaaa tacttagaga gaaagaggaa attgatcaag   5880

agaatgatga actgaaaagg caaattaaaa gactaaccag tggattacag ggcaaacccc   5940

tgacagataa taaacaaagt ctaattgaag aactccaaag gaaagttaaa aaactagaga   6000

accaattaga gggaaaggtg gaggaagtag acctaaaacc tatgaaagaa aagaatgcta   6060

aagaagaatt aattaggtgg gaagaaggta aaaagtggca agccaaaata gaaggaattc   6120

gaaacaagtt aaaagagaaa gagggggaag tctttacttt aacaaagcag ttgaatactt   6180

tgaaggatct ttttgccaaa gccgataaag agaaacttac tttgcagagg aaactaaaaa   6240

caactggcat gactgttgat caggttttgg gaatacgagc tttggagtca gaaaaagaat   6300

tggaagaatt aaaaaagaga aatcttgact tagaaaatga tatattgtat atgagggccc   6360

accaagctct tcctcgagat tctgttgtag aagatttaca tttacaaaat agatacctcc   6420

aagaaaaact tcatgcttta gaaaaacagt tttcaaagga tacatattct aagccttcaa   6480

tttcaggaat agagtcagat gatcattgtc agagagaaca ggagcttcag aaggaaaact   6540

tgaagttgtc atctgaaaat attgaactga aatttcagct tgaacaagca aataaagatt   6600

tgccaagatt aaagaatcaa gtcagagatt tgaaggaaat gtgtgaattt cttaagaaag   6660

aaaaagcaga agttcagcgg aaacttggcc atgttagagg gtctggtaga agtggaaaga   6720

caatcccaga actggaaaaa accattggtt taatgaaaaa agtagttgaa aaagtccaga   6780

gagaaaatga acagttgaaa aaagcatcag gaatattgac tagtgaaaaa atggctaata   6840

ttgagcagga aaatgaaaaa ttgaaggctg aattagaaaa acttaaagct catcttgggc   6900

atcagttgag catgcactat gaatccaaga ccaaaggcac agaaaaaatt attgctgaaa   6960

atgaaaggct tcgtaaagaa cttaaaaaag aaactgatgc tgcagagaaa ttacggatag   7020

caaagaataa tttagagata ttaaatgaga agatgacagt tcaactagaa gagactggta   7080

agagattgca gtttgcagaa agcagaggtc cacagcttga aggtgctgac agtaagagct   7140

ggaaatccat tgtggttaca agaatgtatg aaaccaagtt aaaagaattg gaaactgata   7200

ttgccaaaaa aaatcaaagc attactgacc ttaaacagct tgtaaaagaa gcaacagaga   7260

gagaacaaaa agttaacaaa tacaatgaag accttgaaca acagattaag attcttaaac   7320

atgttcctga aggtgctgag acagagcaag gccttaaacg ggagcttcaa gttcttagat   7380

tagctaatca tcagctggat aaagagaaag cagaattaat ccatcagata gaagctaaca   7440

aggaccaaag tggagctgaa agcaccatac ctgatgctga tcaactaaag gaaaaaataa   7500

aagatctaga gacacagctc aaaatgtcag atctagaaaa gcagcatttg aaggaggaaa   7560

taaagaagct gaaaaaagaa ctggaaaatt ttgatccttc attttttgaa gaaattgaag   7620

atcttaagta taattacaag gaagaagtga agaagaatat tctcttagaa gagaaggtaa   7680

aaaaactttc agaacaattg ggagttgaat taactagccc tgttgctgct tctgaagagt   7740

ttgaagatga agaagaaagt cctgttaatt tccccattta ctaaaggtca cctataaact   7800

ttgtttcatt taactattta ttaactttat aagttaaata tacttggaaa taagcagttc   7860

tccgaactgt agtatttcct tctcactacc ttgtaccttt atacttagat tggaattctt   7920

aataaataaa attatatgaa attttcaact tattaaaaaa aaaaaaaaaa aa           7972


<210>  979
<211>  3705
<212>  DNA
<213>  Homo sapiens

<400>  979
acggcgcgcg gcgagctgag ggtggcggcg gtcgacatgt tccaggtccc ggatagcgag     60

ggcggccgcg ccggctccag ggccatgaag cccccaggag gagaatcgag caatcttttt    120

ggaagtccag aagaagctac tccttccagc aggcctaata ggatggcatc taatattttt    180

ggaccaacag aagaacctca gaacataccc aagaggacaa atcccccagg gggtaaagga    240

agtggtatct ttgacgaatc aacccccgtg cagactcgac agcacctgaa cccacctgga    300

gggaagacca gcgacatttt tgggtctccg gtcactgcca cttcacgctt ggcacaccca    360

aacaaaccca aggatcatgt tttcttatgt gaaggagaag aaccaaaatc ggatcttaaa    420

gctgcaagga gcatcccggc tggagcagag ccaggtgaga aaggcagcgc cagaaaagca    480

ggccccgcca aggagcagga gcccatgccc acagtcgaca gccatgagcc ccggctgggg    540

ccgcggcctc gctctcacaa caaggtcctg aacccaccgg gaggcaaatc cagcatctcc    600

ttctactaag agaagccact gctccacccg gagccagacc agaaactcaa gagatagggt    660

agccatgttt tcatttcctt ttgcccaaat gagcggggtg ggaagagggt tagtcttatg    720

tgagcctggc tgctcagcgt ctcctggccg tcatgacagc tgcttggaga cccgtgcctt    780

ccagatggct gggagatgcc tctgtgggga tgaaatgggg cacccctggc catcactcat    840

gtgtagtcca ggtttgagag gaactggaag gggggtgagg gtggggaggt ggggcagggc    900

atggtccttg gatcaacagc ccgccagctg attggatgtc taggaatgac tgaaagaaac    960

caaaacagcc tgtccactgc tgctgtggga tggaggaggc gtaagcagaa acactaacag   1020

tatattgacc tcttagcaga accgcttcca ttctggagat cacggctgct aaatccagca   1080

tccccacttc attttacccc cagcatattg ttctgtagtc ttttcttgaa acatcttgat   1140

tgcttttcct cggcagcttt caaaaaacca aataataata gttatccgtc ttctacttca   1200

tggaagattg ttttggtgcc ctgaccctct gaagtgccca gttcctgcca tctgaaacct   1260

cggcctgatc tgatctcatg ttggaatctg cctgtctttc acacagggct ggtcttggtc   1320

ctttacatgc cagttttgct tgtgaattct tgcttttttc ctctcatcag ccttaagttt   1380

aggcgtttgt tgttctccag tgatgtagac agttcccttc acaagtcaca gttcttccca   1440

taaatgaggc ccgctgacct ctgcgggact ttaaaaatct attcagatat ttccgagtaa   1500

gtggcttgtt taaattcttc ctgtgtcttt ctttattcct taattggttg gtggaaagaa   1560

gagatgcttg ggaaccttgg gttcttaggt ttggattctt taataatatc taaaaagcta   1620

aattttaaat accagcttta cataaatgat tgttgactct ggtctgtttc tgacaccttt   1680

ccagaaaaaa gtcaattgtt caggtacacc aaagaggaag aagagctgtg gaggccaccc   1740

tctacaaagc tttatagaac ttctggatct aactcacaaa caagcttcca gaagagacta   1800

gagaccttag gccaggagat gaaggagttc agtagcaaag tcacacctgt ccaattccct   1860

gagctttgct cactcagcta atgggatggc aaaggtggtg gtgctttcat cttcaggcag   1920

aagcctctgc ccatccccct caagggctgc aggcccagtt ctcatgctgc ccttgggtgg   1980

gcatctgtta acagaggaga acgtctgggt ggcggcagca gctttgctct gagtgcctac   2040

aaagctaatg cttggtgcta gaaacatcat cattattaaa cttcagaaaa gcagcagcca   2100

tgttcagtca ggctcatgct gcctcactgc ttaagtgcct gcaggagccg cctgccaagc   2160

tccccttcct acacctggca cactggggtc tgcacaaggc tttgtcaacc aaagacagct   2220

tccccctttt gattgcctgt agactttgga gccaagaaac actctgtgtg actctacaca   2280

cacttcaggt ggtttgtgct tcaaagtcat tgatgcaact tgaaaggaaa cagtttaatg   2340

gtggaaatga actaccattt ataacttctg tttttttatt gagaaaatga ttcacgaatt   2400

ccaaatcaga ttgccaggaa gaaataggac gtgacggtac tgggccctgt gattctccca   2460

gcccttgcag tccgctaggt gagaggaaaa gctctttact tccgcccctg gcagggactt   2520

ctgggttatg ggagaaacca gagatgggaa tgaggaaaat atgaactaca gcagaagccc   2580

ctgggcagct gtgatggagc ccctgacatt actcttcttg catctgtcct gccttctttc   2640

cctctgcgag gcagtggggt gggattcaga gtgcttagtc tgctcactgg gagaagaaga   2700

gttcctgcgc atgcaagccc tgctgtgtgg ctgtcgttta catttgggag gtgtcctgta   2760

tgtctgtacg ttggggactg cctgtatttg gaagatttaa aaacctagca tcctgttctc   2820

accctctaag ctgcattgag aaatgactcg tctctgtatt tgtattaagc cttaacactt   2880

ttcttaagtg cattcggtgc caacattttt tagagctgta ccaaaacaaa aagcctgtac   2940

tcacatcaca atgtcatttt gataggagcg ttttgttatt tttacaaggc agaatggggt   3000

gtaacagttg aattaaactt agcaatcacg tgctcagagc ttttgcctgt cagttgtgtg   3060

tgtcccttat agtcccttcc cccacagctc ttgctgaaag agtttgcctt gttttgtttt   3120

gttgttttgt atttagccag aggatgccaa aattagtctt ctcaaagctt tgagtagagt   3180

aagtgtggga ataagccagt tttttttttt ctgtttctgt aacttaaatg aacgggtttt   3240

tttcccttgt atgccacttg tcctaacatg tccttaaggt gtttaacctg cctctgacct   3300

ggcttgcaat gcataggtga ggagaagcag agagcttgtc atatgcaagt cctgtcaaga   3360

aaacaggtgg gcatggtggc tcaggtctgt agtctttggg tctttgggag gccagggtgg   3420

gaggatcact tgagctcagg agtttgagac cagcctagac aacatactac gaccctgtct   3480

atacaaaaaa aaacttctct aaattagccg gatgtggtgg tgcatgcctg tagtcccagc   3540

tactcgggag gctgagtgag gcaggaggat cacttgagac caggaggttg tggctgtagt   3600

gagtgatgat catgccactg cacttcagcc tggaccacag agcaagaccc tgtgtaaaaa   3660

aataaaataa aaaacagatt ggaaaaaaaa aaaaaaaaaa aaaaa                   3705


<210>  980
<211>  2056
<212>  DNA
<213>  Homo sapiens

<400>  980
accgtattgt tccgcgctcg gccggggagg gcgcggggcg ctcggcttcc cgtgttcctc     60

tccccgcccc agccccgtgg gcgcgagagg aggcgggggg ctccttgtgc accagagacg    120

cagctgcctt gttcgcccgg tggggtgtgg atcctccgag cggtgctggg aagggggttc    180

tctctgcccg cgcgcccagg actctaccca gggcggaggt cccgagtggg ccgccccccg    240

cagcgccctg ggttcgcggg cccagaggct ggaggcagcg gggagctagg gtccttcacc    300

ctcccctcgc cgcgtgcctc cgcaggagtc gggctccccg ttccccgcga tggccgcggg    360

ccgcagtcgt acggagccgc cgcgcggacc ccggggcgcc cctccctagc ggggcgcagc    420

tccttcttgt tccccgccct gccagcggga tggggggcgg cgggtcggcc ctgagggtct    480

gcgccgacca ccgcgggggc atcaactggc tgagcctgag ccccgacggg cagcgcctgc    540

tgacgggcag cgaggacggc acggcccggc tctggagcac cgcggacggc cagtgctgcg    600

cgctcctgca aggacatgaa agctatgtga ccttctgcca gctggaggat gaggctgcct    660

tcacatgcag cgccgactgc accatcagga ggtgggacgt gctgaccggg cagtgtctgc    720

aggtgtaccg aggacacacg tccatcgtga acaggatcct ggttgccaac aaccagctct    780

tcagcagctc ctatgaccgg acagctcggg tctggagtgt ggacaagggg cagatgtccc    840

gggagttccg gggccaccgc aactgcgtgc tgaccctagc ctactctgcc ccgtgggacc    900

tccccagcac tccctgcgcg gaggaggccg cggccggggg gcttctggtg accggcagca    960

cagatggcac agccaaggtg tggcaggtgg ccagcggctg ctgccaccag acgctgcggg   1020

gccacacggg tgcagtgctg tgcctagtgc tagacacgcc cggccacacg gccttcacag   1080

gcagcaccga cgccaccatc cgtgcctggg acatcctgag tggggagcag ctgcgggtgt   1140

tccgggagca ccggggctcc gtcatctgtc tggagctggt gaaccgactc gtgtactctg   1200

gcagcgcgga caggaccgtc aagtgctggc tggcagacac aggggagtgt gtgcgcacgt   1260

tcacggccca cagacgcaac gtgagcgccc tcaagtacca cgcgggcacc ttgttcacgg   1320

gcagcgggga cgcttgcgcc cgggccttcg acgcgcagtc tggagagctg cggagggtgt   1380

tccggggcca cacattcatc atcaactgca tccaggtgca cggccaggtg ctctacaccg   1440

cctcgcacga cggcgccctg cgcctctggg acgtgcgcgg gctccgaggt gccccgcggc   1500

cccctccgcc catgcgcagc ctctcgcggc tcttcagcaa caaggtgggc tgcgccgccg   1560

cgcccctgca gccggcctga tcccgcgggg cccctgcaga cgccagccca gacacccagc   1620

ggctcccaga gcgccccgcc ctgctacccg cggtggtggc gcccgatggc cggcgagggg   1680

cgaggagcga ggaagcccgg gcgggaggag agcccgtcgc aggcgtctgg tttttctttg   1740

gtggccagga ggcgctggga gcgggagtgc tcgccctggg gaccgccccc ttttcccttt   1800

tagggtggct cctgtcctcc ctccccatcc ctgacctggc gaaaggccta gtcctgggga   1860

ccctcccacc tcaggggctg caggcggact gccccagctc ccccagcccc acgaaactgg   1920

gcctttcctg ctgagaggaa gtgacttttt acagaagcca ctgaacctgg ttattttggc   1980

aaatcgtccg tctcgagggc cttgggggga actgaaatat acagcctgaa cgttaaaagt   2040

gaaaaaaaaa aaaaaa                                                   2056


<210>  981
<211>  750
<212>  DNA
<213>  Homo sapiens

<400>  981
acactataga atcgtcgact ctggaccttg gctgtcactc agttgacaca cgcacgccgg     60

gcgtgccagt ttataaaggg agagagcaag cagcgagtct tgaagctctg tttggtgctt    120

tggatccatt tccatcggtc cttacagccg ctcgtcagac tccagcagcc aagatggtga    180

agcagatcga gagcaagact gcttttcagg aagccttgga cgctgcaggt gataaacttg    240

tagtagttga cttctcagcc acgtggtgtg ggccttgcaa aatgatcaag cctttctttc    300

attccctctc tgaaaagtat tccaacgtga tattccttga agtagatgtg gatgactgtc    360

aggatgttgc ttcagagtgt gaagtcaaat gcatgccaac attccagttt tttaagaagg    420

gacaaaaggt gggtgaattt tctggagcca ataaggaaaa gcttgaagcc accattaatg    480

aattagtcta atcatgtttt ctgaaaacat aaccagccat tggctattta aaacttgtaa    540

tttttttaat ttacaaaaat ataaaatatg aagacataaa cccagttgcc atctgcgtga    600

caataaaaca ttaatgctaa cactttttaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa    660

aaacgagcgg ccgctcccta tagtgagtcg tattaagctt aattagctga gcttggactc    720

ctgttgatag atccagtaat gacctcagaa                                     750


<210>  982
<211>  1729
<212>  DNA
<213>  Homo sapiens

<400>  982
gcatgtgcaa ggccggcttc gcgggcgacg atgccccccg ggccgtcttc ccctccatcg     60

tggggcgccc caggcaccag ggcgtgatgg tgggcatggg tcagaaggat tcctatgtgg    120

gcgacgaggc ccagagcaag agaggcatcc tcaccctgaa gtaccccatc gagcacggca    180

tcgtcaccaa ctgggacgac atggagaaaa tctggcacca caccttctac aatgagctgc    240

gtgtggctcc cgaggagcac cccgtgctgc tgaccgaggc ccccctgaac cccaaggcca    300

acctcgagaa gatgacccag atcatgtttg agaccttcaa caccccagcc atgtacgttg    360

ctatccaggc tgtgctatcc ctgtacgcct ctggccgtac cactggcatc gtgatggact    420

ccggtgacgg ggtcacccac actgtgccca tctacgaggg gtatgccctc ccccatgcca    480

tcctgcgtct ggacctggct ggccgggacc tgactgacta cctcatgaag atcctcaccg    540

agcgcggcta cagcttcacc accacggccg agcgggaaat cgtgcgtgac attaaggaga    600

agctgtgcta cgtcgccctg gacttcgagc aagagatggc cacggctgct tccagctcct    660

ccctggagaa gagctacgag ctgcctgacg gccaggtcat caccattggc aatgagcggt    720

tccgctgccc tgaggcactc ttccagcctt ccttcctggg catggagtcc tgtggcatcc    780

acgaaactac cttcaactcc atcatgaagt gtgacgtgga catccgcaaa gacctgtacg    840

ccaacacagt gctgtctggc ggcaccacca tgtaccctgg cattgccgac aggatgcaga    900

aggagatcac tgccctggca cccagcacaa tgaagatcaa gatcattgct cctcctgagc    960

gcaagtactc cgtgtggatc ggcggctcca tcctggcctc gctgtccacc ttccagcaga   1020

tgtggatcag caagcaggag tatgacgagt ccggcccctc catcgtccac cgcaaatgct   1080

tctaggcgga ctatgactta gttgcgttac accctttctt gacaaaacct aacttgcgca   1140

gaaaacaaga tgagattggc atggctttat ttgttttttt tgttttgttt tggttttttt   1200

tttttttggc ttgactcagg atttaaaaac tggaacggtg aaggtgacag cagtcggttg   1260

gagcgagcat cccccaaagt tcacaatgtg gccgaggact ttgattgcac attgttgttt   1320

ttttaatagt cattccaaat atgagatgcg ttgttacagg aagtcccttg ccatcctaaa   1380

agccacccca cttctctcta aggagaatgg cccagtcctc tcccaagtcc acacagggga   1440

ggtgatagca ttgctttcgt gtaaattatg taatgcaaaa tttttttaat cttcgcctta   1500

atactttttt attttgtttt attttgaatg atgagccttc gtgccccccc ttcccccttt   1560

tttttgtccc ccaacttgag atgtatgaag gcttttggtc tccctgggag tgggtggagg   1620

cagccagggc ttacctgtac actgacttga gaccagttga ataaaagtgc acaccttaaa   1680

aatgaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa               1729


<210>  983
<211>  1862
<212>  DNA
<213>  Homo sapiens

<400>  983
gtcagtccgg aggctgcggc tgcagaagta ccgcctgcgg agtaactgca aagatgctgt     60

ccgtgcgcgt tgctgcggcc gtggtccgcg cccttcctcg gcgggccgga ctggtctcca    120

gaaatgcttt gggttcatct ttcattgctg caaggaactt ccatgcctct aacactcatc    180

ttcaaaagac tgggactgct gagatgtcct ctattcttga agagcgtatt cttggagctg    240

atacctctgt tgatcttgaa gaaactgggc gtgtcttaag tattggtgat ggtattgccc    300

gcgtacatgg gctgaggaat gttcaagcag aagaaatggt agagttttct tcaggcttaa    360

agggtatgtc cttgaacttg gaacctgaca atgttggtgt tgtcgtgttt ggaaatgata    420

aactaattaa ggaaggagat atagtgaaga ggacaggagc cattgtggac gttccagttg    480

gtgaggagct gttgggtcgt gtagttgatg cccttggtaa tgctattgat ggaaagggtc    540

caattggttc caagacgcgt aggcgagttg gtctgaaagc ccccggtatc attcctcgaa    600

tttcagtgcg ggaaccaatg cagactggca ttaaggctgt ggatagcttg gtgccaattg    660

gtcgtggtca gcgtgaactg attattggtg accgacagac tgggaaaacc tcaattgcta    720

ttgacacaat cattaaccag aaacgtttca atgatggatc tgatgaaaag aagaagctgt    780

actgtattta tgttgctatt ggtcaaaaga gatccactgt tgcccagttg gtgaagagac    840

ttacagatgc agatgccatg aagtacacca ttgtggtgtc ggctacggcc tcggatgctg    900

ccccacttca gtacctggct ccttactctg gctgttccat gggagagtat tttagagaca    960

atggcaaaca tgctttgatc atctatgacg acttatccaa acaggctgtt gcttaccgtc   1020

agatgtctct gttgctccgc cgaccccctg gtcgtgaggc ctatcctggt gatgtgttct   1080

acctacactc ccggttgctg gagagagcag ccaaaatgaa cgatgctttt ggtggtggct   1140

ccttgactgc tttgccagtc atagaaacac aggctggtga tgtgtctgct tacattccaa   1200

caaatgtcat ttccatcact gacggacaga tcttcttgga aacagaattg ttctacaaag   1260

gtatccgccc tgcaattaac gttggtctgt ctgtatctcg tgtcggatcc gctgcccaaa   1320

ccagggctat gaagcaggta gcaggtacca tgaagctgga attggctcag tatcgtgagg   1380

ttgctgcttt tgcccagttc ggttctgacc tcgatgctgc cactcaacaa cttttgagtc   1440

gtggcgtgcg tctaactgag ttgctgaagc aaggacagta ttctcccatg gctattgaag   1500

aacaagtggc tgttatctat gcgggtgtaa ggggatatct tgataaactg gagcccagca   1560

agattacaaa gtttgagaat gctttcttgt ctcatgtcgt cagccagcac caagccttgt   1620

tgggcactat cagggctgat ggaaagatct cagaacaatc agatgcaaag ctgaaagaga   1680

ttgtaacaaa tttcttggct ggatttgaag cttaaactcc tgtggattca catcaaatac   1740

cagttcagtt ttgtcattgt tctagtaaat tagttccatt tgtaaaaggg ttactctcat   1800

actccttatg tacagaaatc acatgaaaaa taaaggttcc ataatgcaaa aaaaaaaaaa   1860

aa                                                                  1862


<210>  984
<211>  1762
<212>  DNA
<213>  Homo sapiens

<400>  984
ggactacgcc atgttggggt ttgtgggtcg ggtggccgct gctccggcct ccggggcctt     60

gcggagactc accccttcag cgtcgctgcc cccagctcag ctcttactgc gggccgctcc    120

gacggcggtc catcctgtca gggactatgc ggcgcaaaca tctccttcgc caaaagcagg    180

cgccgccacc gggcgcatcg tggcggtcat tggcgcagtg gtggacgtcc agtttgatga    240

gggactacca ccaattctaa atgccctgga agtgcaaggc agggagacca gactggtttt    300

ggaggtggcc cagcatttgg gtgagagcac agtaaggact attgctatgg atggtacaga    360

aggcttggtt agaggccaga aagtactgga ttctggtgca ccaatcaaaa ttcctgttgg    420

tcctgagact ttgggcagaa tcatgaatgt cattggagaa cctattgatg aaagaggtcc    480

catcaaaacc aaacaatttg ctcccattca tgctgaggct ccagagttca tggaaatgag    540

tgttgagcag gaaattctgg tgactggtat caaggttgtc gatctgctag ctccctatgc    600

caagggtggc aaaattgggc tttttggtgg tgctggagtt ggcaagactg tactgatcat    660

ggagttaatc aacaatgtcg ccaaagccca tggtggttac tctgtgtttg ctggtgttgg    720

tgagaggacc cgtgaaggca atgatttata ccatgaaatg attgaatctg gtgttatcaa    780

cttaaaagat gccacctcta aggtagcgct ggtatatggt caaatgaatg aaccacctgg    840

tgctcgtgcc cgggtagctc tgactgggct gactgtggct gaatacttca gagaccaaga    900

aggtcaagat gtactgctat ttattgataa catctttcgc ttcacccagg ctggttcaga    960

ggtgtctgca ttattgggcc gaatcccttc tgctgtgggc tatcagccta ccctggccac   1020

tgacatgggt actatgcagg aaagaattac cactaccaag aagggatcta tcacctctgt   1080

acaggctatc tatgtgcctg ctgatgactt gactgaccct gcccctgcta ctacgtttgc   1140

ccatttggat gctaccactg tactgtcgcg tgccattgct gagctgggca tctatccagc   1200

tgtggatcct ctagactcca cctctcgtat catggatccc aacattgttg gcagtgagca   1260

ttacgatgtt gcccgtgggg tgcaaaagat cctgcaggac tacaaatccc tccaggatat   1320

cattgccatc ctgggtatgg atgaactttc tgaggaagac aagttgaccg tgtcccgtgc   1380

acggaaaata cagcgtttct tgtctcagcc attccaggtt gctgaggtct tcacaggtca   1440

tatggggaag ctggtacccc tgaaggagac catcaaagga ttccagcaga ttttggcagg   1500

tgaatatgac catctcccag aacaggcctt ctatatggtg ggacccattg aagaagctgt   1560

ggcaaaagct gataagctgg ctgaagagca ttcatcgtga ggggtctttg tcctctgtac   1620

tgtctctctc cttgccccta acccaaaaag cttcattttt ctgtgtaggc tgcacaagag   1680

ccttgattga agatatattc tttctgaaca gtatttaagg tttccaataa aatgtacacc   1740

cctcagaaaa aaaaaaaaaa aa                                            1762


<210>  985
<211>  1278
<212>  DNA
<213>  Homo sapiens

<400>  985
ccattggcct gtagattcac ctcccctggg cagggcccca ggacccagga taatatctgt     60

gcctcctgcc cagaaccctc caagcagaca caatggtaag aatggtgcct gtcctgctgt    120

ctctgctgct gcttctgggt cctgctgtcc cccaggagaa ccaagatggt cgttactctc    180

tgacctatat ctacactggg ctgtccaagc atgttgaaga cgtccccgcg tttcaggccc    240

ttggctcact caatgacctc cagttcttta gatacaacag taaagacagg aagtctcagc    300

ccatgggact ctggagacag gtggaaggaa tggaggattg gaagcaggac agccaacttc    360

agaaggccag ggaggacatc tttatggaga ccctgaaaga catcgtggag tattacaacg    420

acagtaacgg gtctcacgta ttgcagggaa ggtttggttg tgagatcgag aataacagaa    480

gcagcggagc attctggaaa tattactatg atggaaagga ctacattgaa ttcaacaaag    540

aaatcccagc ctgggtcccc ttcgacccag cagcccagat aaccaagcag aagtgggagg    600

cagaaccagt ctacgtgcag cgggccaagg cttacctgga ggaggagtgc cctgcgactc    660

tgcggaaata cctgaaatac agcaaaaata tcctggaccg gcaagatcct ccctctgtgg    720

tggtcaccag ccaccaggcc ccaggagaaa agaagaaact gaagtgcctg gcctacgact    780

tctacccagg gaaaattgat gtgcactgga ctcgggccgg cgaggtgcag gagcctgagt    840

tacggggaga tgttcttcac aatggaaatg gcacttacca gtcctgggtg gtggtggcag    900

tgcccccgca ggacacagcc ccctactcct gccacgtgca gcacagcagc ctggcccagc    960

ccctcgtggt gccctgggag gccagctagg aagcaagggt tggaggcaat gtgggatctc   1020

agacccagta gctgcccttc ctgcctgatg tgggagctga accacagaaa tcacagtcaa   1080

tggatccaca aggcctgagg agcagtgtgg ggggacagac aggaggtgga tttggagacc   1140

gaagactggg atgcctgtct tgagtagact tggacccaaa aaatcatctc accttgagcc   1200

cacccccacc ccattgtcta atctgtagaa gctaataaat aatcatccct ccttgcctag   1260

cataaaaaaa aaaaaaaa                                                 1278


<210>  986
<211>  1864
<212>  DNA
<213>  Homo sapiens

<400>  986
gcgcccggcg aaaccaccct cccgtgcagc cgagcccagc cgctctccgg ccgccgtccc     60

cggcggcccc atgccccgat gccccgcggg ggccatggac gaggggcccg tggacctgcg    120

cacccggccc aaggccgccg gactcccggg cgccgcgctg ccgctccgca agcgcccgct    180

gcgcgcgccc tccccggagc ccgccgctcc ccgcggcgct gcgggccttg tcgtccccct    240

ggaccctctg cgcggcggct gcgacctgcc ggcggtcccc gggccccccc acggcctggc    300

ccggccggag gcgctttact accccggagc cttactgcct ttgtacccca ctcgggccat    360

gggctccccg tttcctctgg tgaacctgcc tacaccccta taccccatga tgtgccccat    420

ggaacacccc ctttctgctg acatcgccat ggccacccgt gcagatgagg acggagacac    480

gcctctccat attgctgtgg tgcagggtaa cctgccagct gtgcaccggc tggtcaacct    540

cttccagcag gggggccggg agctcgacat ctacaacaac ctacggcaga caccgctcca    600

cctggctgtg atcaccacat taccgtctgt ggtccggctc ctggtgacag ctggtgccag    660

ccccatggcg ctggaccgcc atggccagac ggccgctcac ctggcgtgcg agcaccgcag    720

cccgacctgc ctgcgagccc tgctggacag cgcagctccg ggcacgttgg acctggaggc    780

ccgcaattat gacgggctca ccgccctgca cgtggcagtg aacaccgagt gccaagaaac    840

cgtgcagctc ttgctagagc gcggtgccga catcgacgca gtggacatta agagcggccg    900

ctccccgctc atccacgccg tggaaaacaa cagccttagc atggtgcagc tgctgctgca    960

gcacggcgcc aacgtgaacg cgcaaatgta ctccggcagc tccgccctgc actcagcgtc   1020

cggccgcggg ctcctcccgc tggtgcgcac gctggtccgc agcggcgctg acagcagcct   1080

caagaactgc cacaacgaca cgccgctcat ggtggcgcgc agccgcaggg tcatcgacat   1140

cctgaggggg aaggccaccc ggcctgcttc cacctcccag ccagacccct cccctgaccg   1200

gagcgccaac acctcccccg agagcagcag ccgcctcagc tccaatggtc ttctctccgc   1260

atcaccatcc tcctcaccct cccagtctcc ccccagggac ccccctggat tccccatggc   1320

tcctcccaat ttcttccttc cttccccatc tccacccgcc ttcctgccct ttgctggggt   1380

cctccgaggc cctggccggc cggtgccccc ctccccagct ccaggaggca gctgaggggg   1440

atgggggggc agatcttgga ctcatgagga ggggcccccc tgccctgtgg ggtcaaccct   1500

tctggaaact gtgaagatct cactctgccc ccccccccca tcttcgggac caggatttgc   1560

acagaagcac atgcacctac ccatacaccc cctcttctga gcacagatgt tcccccatct   1620

cgctccctcc caggactctg accccagcat tctcaggcac cagtccctgt ccggaatgcc   1680

acccacatct tccatttcca tgtcccctcc cagagctggt ggacccaggg aacagccact   1740

cccctccact ctctaccaga taactgagga ggggagaggt gggccgtaac gggcacggat   1800

cacgatgtaa attattaagc attttggttg gatttctttt gtaataaact atttttgtac   1860

cata                                                                1864


<210>  987
<211>  5777
<212>  DNA
<213>  Homo sapiens

<400>  987
attcatgagg cgcgcgcagc ccggcatgct aatgaggcgg ggcgcggcgg ctggctaaag     60

agcgactggg cggcggcggg cgcggagctg ccaggcggga gcggcgtagg cgcggggtcg    120

ccggccagcg tgaaccggga catggagccg cccggcggga gcctggggcc cggccgcggg    180

acccgggaca agaagaaggg ccggagccca gatgagctgc cctcggcggg cggcgacggc    240

ggcaaatcta agaaatttct ggagagattt accagcatga gaattaagaa ggagaaggaa    300

aagcccaatt ctgctcatag aaattcttct gcatcatatg gggatgatcc cacagcacag    360

tcattgcaag atgtttcaga tgaacaagtg ctggttctct ttgaacagat gctgctggat    420

atgaacctga atgaggagaa acagcaacct ttgagggaga aggacatcat catcaagagg    480

gagatggtgt cccaatactt gtacacctcc aaggctggca tgagccagaa ggagagctct    540

aagtctgcca tgatgtatat tcaggagttg aggtcaggct tgcgggatat gcctctgctc    600

agctgcctgg agtcccttcg tgtgtctctc aacaacaacc ctgtcagttg ggtgcaaaca    660

tttggtgctg aaggcttggc ctccttattg gacattctta aacgacttca tgatgagaaa    720

gaagagactg ctgggagtta cgatagccgg aacaagcatg agatcattcg ctgcttgaaa    780

gcttttatga acaacaagtt tggaatcaag accatgttgg agacagaaga aggaatccta    840

ctgctggtca gagccatgga tcctgctgtt cccaacatga tgattgatgc agctaagctg    900

ctttctgctc tttgtattct accgcagcca gaggacatga atgaaagggt tttggaggca    960

atgacagaaa gagctgagat ggatgaagtg gaacgtttcc agccgctgct ggatggatta   1020

aaaagtggaa ccactattgc actgaaggtt ggatgcctac agctgatcaa tgctctcatc   1080

acaccagcgg aggaacttga cttccgagtt cacatcagaa gtgaactgat gcgtttgggg   1140

ctacatcagg tgttgcagga ccttcgagag attgaaaatg aagatatgag agtgcaacta   1200

aatgtgtttg atgaacaagg ggaagaggat tcctatgacc tgaagggacg gctggatgac   1260

attcgcatgg agatggatga ctttaatgaa gtctttcaga ttctcttaaa cacagtgaag   1320

gattcaaagg cagagccaca cttcctttcc atcctgcagc acttactctt ggtccgaaat   1380

gactatgagg ccagacctca gtactataag ttgattgaag aatgtatttc ccagatagtt   1440

ctgcacaaga acggggctga tcctgacttc aagtgccggc acctccagat tgagattgag   1500

ggattaattg atcaaatgat tgataagaca aaggtggaga aatctgaagc caaagctgca   1560

gagctggaaa agaagttgga ctcagagtta acagcccgac atgagctaca ggtggaaatg   1620

aaaaagatgg aaagtgactt tgagcagaag cttcaagatc ttcagggaga aaaagatgca   1680

ctgcattctg aaaagcagca aattgccaca gagaaacagg acctggaagc agaggtgtcc   1740

cagctcacag gagaggttgc caagctgaca aaggaactgg aagatgccaa gaaagaaatg   1800

gcttccctct ctgcggcagc tattactgta cctccttctg ttcctagtcg tgctcctgtt   1860

ccccctgccc ctcctttacc tggtgactct ggcactatta ttccaccacc acctgctcct   1920

ggggatagta ccactcctcc tcctcctcct cctcctcctc ctcctccacc tcctttgcct   1980

gggggtgttt gcatctcctc acccccttct ttacctggag gtactgctat ctctccaccc   2040

cctcctttgt ctggggatgc taccatccct ccaccccctc ctttgcctga gggtgttggc   2100

atcccttcac cctcttcttt gcctggaggt actgccatcc ccccacctcc tcctttgcct   2160

gggagtgcta gaatcccccc accaccacct cctttgcctg ggagtgctgg aattcccccc   2220

ccacctcctc ccttgcctgg agaagcagga atgccacctc ctcctccccc tcttcctggt   2280

ggtcctggaa tccctccacc tcctccattt cccggaggcc ctggcattcc tccacctcca   2340

cccggaatgg gtatgcctcc acctccccca tttggatttg gagttcctgc agccccagtt   2400

ctgccatttg gattaacccc caaaaagctt tataagccag aggtgcagct ccggaggcca   2460

aactggtcca agcttgtggc tgaggacctc tcccaggact gcttctggac aaaggtgaag   2520

gaggaccgct ttgagaacaa tgaacttttc gccaaactta cccttacctt ctctgcccag   2580

accaagactt ccaaagccaa gaaggatcaa gaaggtggag aagaaaagaa atctgtgcaa   2640

aagaaaaaag taaaagagtt aaaggtgttg gattcaaaga cagcccagaa tctctcaatc   2700

tttttgggtt ccttccgcat gccctatcaa gagattaaga atgtcatcct ggaggtgaat   2760

gaggctgttc tgactgagtc tatgatccag aacctcatta agcaaatgcc agagccagag   2820

cagttaaaaa tgctttctga actgaaggat gaatatgatg acctggctga gtcagagcag   2880

tttggcgtgg tgatgggcac tgtgccccga ctgcggcctc gcctcaatgc cattctcttc   2940

aagctacaat tcagcgagca agtggagaat atcaagccag agattgtgtc tgtcactgct   3000

gcatgtgagg agttacgtaa gagtgagagc ttttccaatc tcctagagat taccttgctt   3060

gttggaaatt acatgaatgc tggctccaga aatgctggtg cttttggctt caatatcagc   3120

ttcctctgta agcttcgaga caccaagtcc acagatcaga agatgacgtt gttacacttc   3180

ttggctgagt tgtgtgagaa tgactatccc gatgtcctca agtttccaga cgagcttgcc   3240

catgtggaga aagccagccg agtttctgct gaaaacttgc aaaagaacct agatcagatg   3300

aagaaacaaa tttctgatgt ggaacgtgat gttcagaatt tcccagctgc cacagatgaa   3360

aaagacaagt ttgttgaaaa aatgaccagc tttgtgaagg atgcacagga acagtataac   3420

aagctgcgga tgatgcattc taacatggag accctctata aggagctggg cgagtacttc   3480

ctctttgacc ccaagaagtt gtctgttgaa gaatttttca tggatcttca caattttcgg   3540

aatatgtttt tgcaagcagt caaggagaac cagaagcggc gggagacaga agaaaagatg   3600

aggcgagcaa aactagccaa ggagaaggca gagaaggagc ggctagagaa gcagcagaag   3660

agagagcaac tcatagacat gaatgcagag ggcgatgaga caggtgtgat ggacagtctt   3720

ctagaagccc tgcagtcagg ggcagcattc cgacggaaga gagggccccg tcaagccaac   3780

aggaaggccg ggtgtgcagt cacatctctg ctagcttcgg agctgaccaa ggatgatgcc   3840

atggctgctg ttcctgccaa ggtgtccaag aacagtgaga cattccccac aatccttgag   3900

gaagccaagg agttggttgg ccgtgcaagc taatgtgggt cctgtgaccg cggcagctcc   3960

tcagcggagc cgcagactgt cctgccctgc agcatgtgcc taaaggctca aggggatatt   4020

cctctggggt ggccactccc accaccctga ccctgtcttt ctctctggcc tgctgctctc   4080

tcaacatcac atacagcttc agctgcctgg aggccagaag gaaagggcag tgcaggggag   4140

gcctgagccc gacttagcca gccctggctg ttgtattacc aaagcagggt ccatgtttgc   4200

tgccttaacc ctgtctcctc tctgttactc agagggcctc atctcagaca aggcccagcc   4260

tgctttttct cagccctgac tttctaatgg gctttccccc ctaggtcagt cttgctggat   4320

ttgtgctttt cttttgtggt ttctctggcc ctgagaatag catggggctt gtaaaccttt   4380

gggctagatc cctcctttca ttgctgttgt ctctgctctt ccctctcctg gctgtggtta   4440

tttattatta gtggtgtggc actgggagct gctcctaagg aagcagggag caaatcccac   4500

ctttacccca ccttcctggg aaaggcctcc aaagcaaagg atctggacca gtttccctgc   4560

tgtgctgtgg cccaggccag agcctgtggg caggcaggca gggcatagcg acagtgtggg   4620

acctgccccc agcttctgcc acgctttatg cccttgcctc tctggacgct ctgcaccaac   4680

cccaggctac tgagccacct tccctcctca tgccttccct gagctttggt gcatctcatc   4740

tggactatgg gttgtactgt gaccatccca acacctcacc ctctgtctac aaggaaatgg   4800

gaggtggagc ctcctggctg agaaattgtt ttgcaaatgg atctattttt gtatgaaaaa   4860

aaaaattttt ttaaagaaaa ctgttccttc cccctttccc ctccataatg taagaagctt   4920

tggtggcagg ttacagagtt ctgggatttc ttctcacagg cccaatcctg aatgtgcccc   4980

tggaccttct ggacccttga gtccaaggca gatcctctct cccagggaat ccgacacagg   5040

aggaacccct tctctggttg agctgggcca ggcctaagag tagcaggaac tctaagacca   5100

cagagttttt tataaatgta taaatgtatc aagccaaatg tgcagatgct aactggacat   5160

tctggggaac tgggcaccag gagtgccttc atacactgta ccccagctct cttctaaaag   5220

agaagtgggt gggcacactg aactgtttgg tggccccaac cacaggaagc tgcaattctc   5280

tggcttaggg tgatactttt gccctccttg tgcccctctc agctttccat ccccagctag   5340

gaagaaagaa tggcactctt gggcttggcc cagaattaga gttattagag caagagagag   5400

cttaggaagc atgagggcaa ctatagtgag gccttattgc caggagggag ggttttggtt   5460

gctggcgctt gtgtataaag gggcaagagc agctcctttg gactattcct gggaggactc   5520

tgatgcaggg cgtctgttgc tcccctgggt cacctcctcc ctgctcgctg acatctgggg   5580

ctttgaccct ttctttttta atctactttt gctaagatgc atttaataaa aaaaaagaga   5640

gagagagaga ggtgtgaggg acaaaatgca aacctatttc ccttgcctca taggcttctg   5700

ggatgtcatc acctccagtt tgttggtttt gtttccaact gttaataaag cattgaaaca   5760

gtaaaaaaaa aaaaaaa                                                  5777


<210>  988
<211>  1552
<212>  DNA
<213>  Homo sapiens

<400>  988
aactgtcgta cgtatgtctt ctgtttcgtc ctcgctttcc ggctgctgtt tctccacggc     60

tctcctcttt ccccctccct tctctcccgg gcggcttact ttgcggcagc gccgagaacc    120

ccaccccctt tctttgcgga atcaccatgg cggctgggac cctgtacacg tatcctgaaa    180

actggagggc cttcaaggct ctcatcgctg ctcagtacag cggggctcag gtccgcgtgc    240

tctccgcacc accccacttc cattttggcc aaaccaaccg cacccctgaa tttctccgca    300

aatttcctgc cggcaaggtc ccagcatttg agggtgatga tggattctgt gtgtttgaga    360

gcaacgccat tgcctactat gtgagcaatg aggagctgcg gggaagtact ccagaggcag    420

cagcccaggt ggtgcagtgg gtgagctttg ctgattccga tatagtgccc ccagccagta    480

cctgggtgtt ccccaccttg ggcatcatgc accacaacaa acaggccact gagaatgcaa    540

aggaggaagt gaggcgaatt ctggggctgc tggatgctta cttgaagacg aggacttttc    600

tggtgggcga acgagtgaca ttggctgaca tcacagttgt ctgcaccctg ttgtggctct    660

ataagcaggt tctagagcct tctttccgcc aggcctttcc caataccaac cgctggttcc    720

tcacctgcat taaccagccc cagttccggg ctgtcttggg cgaagtgaaa ctgtgtgaga    780

agatggccca gtttgatgct aaaaagtttg cagagaccca acctaaaaag gacacaccac    840

ggaaagagaa gggttcacgg gaagagaagc agaagcccca ggctgagcgg aaggaggaga    900

aaaaggcggc tgcccctgct cctgaggagg agatggatga atgtgagcag gcgctggctg    960

ctgagcccaa ggccaaggac cccttcgctc acctgcccaa gagtaccttt gtgttggatg   1020

aatttaagcg caagtactcc aatgaggaca cactctctgt ggcactgcca tatttctggg   1080

agcactttga taaggacggc tggtccctgt ggtactcaga gtatcgcttc cctgaagaac   1140

tcactcagac cttcatgagc tgcaatctca tcactggaat gttccagcga ctggacaagc   1200

tgaggaagaa tgccttcgcc agtgtcatcc tttttggaac caacaatagc agctccattt   1260

ctggagtctg ggtcttccga ggccaggagc ttgcctttcc gctgagtcca gattggcagg   1320

tggactacga gtcatacaca tggcggaaac tggatcctgg cagcgaggag acccagacgc   1380

tggttcgaga gtacttttcc tgggaggggg ccttccagca tgtgggcaaa gccttcaatc   1440

agggcaagat cttcaagtga acatctcttg ccatcaccta gctgcctgca cctgcccttc   1500

agggagatgg gggtcattaa aggaaactga acattgaaaa aaaaaaaaaa aa           1552


<210>  989
<211>  1894
<212>  DNA
<213>  Homo sapiens

<400>  989
ggaactaacg tcatgccgag ttgctgagcg ccggcaggcg gggccggggc ggccaaacca     60

atgcgatggc cggggcggag tcgggcgctc tataagttgt cgataggcgg gcactccgcc    120

ctagtttcta aggatcatgt ctgcgagcca ggattcccga tccagagaca atggccccga    180

tgggatggag cccgaaggcg tcatcgagag taactggaat gagattgttg acagctttga    240

tgacatgaac ctctcggagt cccttctccg tggcatctac gcgtatggtt ttgagaagcc    300

ctctgccatc cagcagcgag ccattctacc ttgtatcaag ggttatgatg tgattgctca    360

agcccaatct gggactggga aaacggccac atttgccata tcgattctgc agcagattga    420

attagatcta aaagccaccc aggccttggt cctagcaccc actcgagaat tggctcagca    480

gatacagaag gtggtcatgg cactaggaga ctacatgggc gcctcctgtc acgcctgtat    540

cgggggcacc aacgtgcgtg ctgaggtgca gaaactgcag atggaagctc cccacatcat    600

cgtgggtacc cctggccgtg tgtttgatat gcttaaccgg agatacctgt cccccaaata    660

catcaagatg tttgtactgg atgaagctga cgaaatgtta agccgtggat tcaaggacca    720

gatctatgac atattccaaa agctcaacag caacacccag gtagttttgc tgtcagccac    780

aatgccttct gatgtgcttg aggtgaccaa gaagttcatg agggacccca ttcggattct    840

tgtcaagaag gaagagttga ccctggaggg tatccgccag ttctacatca acgtggaacg    900

agaggagtgg aagctggaca cactatgtga cttgtatgaa accctgacca tcacccaggc    960

agtcatcttc atcaacaccc ggaggaaggt ggactggctc accgagaaga tgcatgctcg   1020

agatttcact gtatccgcca tgcatggaga tatggaccaa aaggaacgag acgtgattat   1080

gagggagttt cgttctggct ctagcagagt tttgattacc actgacctgc tggccagagg   1140

cattgatgtg cagcaggttt ctttagtcat caactatgac cttcccacca acagggaaaa   1200

ctatatccac agaatcggtc gaggtggacg gtttggccgt aaaggtgtgg ctattaacat   1260

ggtgacagaa gaagacaaga ggactcttcg agacattgag accttctaca acacctccat   1320

tgaggaaatg cccctcaatg ttgctgacct catctgaggg gctgtcctgc cacccagccc   1380

cagccagggc tcaatctctg ggggctgagg agcagcagga ggggggaggg aagggagcca   1440

agggatggac atcttgtcat tttttttctt tgaataaatg tcactttttg aggcaaaaga   1500

aggaaccgtg aacattttag acaccctttt ctttggggta ggctcttgcc ccaggcgccg   1560

gctcttctcc caaaaaaaaa aaaaaaacac taatccattt ccctaaccta gtaacctcca   1620

gatcccagag gctctcctca cctcagctga gctcctttga aagtgattca agggactatg   1680

tcactcagcc tcatttgctg gaccaaatct ggagggagaa cccctaaaac ccctaagtga   1740

ggttgcccag ggggttgtcc ccaggtgggg ggaagcaggg gagagaaaat ggtagccatt   1800

tttacattgt tttgtatagt atttattgat tcaggaaaca aacacaaaat tctgaataaa   1860

atgacttgga aactgccaaa aaaaaaaaaa aaaa                               1894


<210>  990
<211>  1643
<212>  DNA
<213>  Homo sapiens

<400>  990
tttccgggac gtcgcgcgcc gtgtggggcg cgcacgcagg gctgggcgtg agggggcgtg     60

cgcgtgcgca ggcgacgcgc cgaggtacta ggcagagccg tggaaccgcc gccaggtcgc    120

tgttggtcca cgccgcccgt cgcgccgccc gcccgctcag cgtccgccgc cgccatggga    180

gtgcaggtgg aaaccatctc cccaggagac gggcgcacct tccccaagcg cggccagacc    240

tgcgtggtgc actacaccgg gatgcttgaa gatggaaaga aatttgattc ctcccgggac    300

agaaacaagc cctttaagtt tatgctaggc aagcaggagg tgatccgagg ctgggaagaa    360

ggggttgccc agatgagtgt gggtcagaga gccaaactga ctatatctcc agattatgcc    420

tatggtgcca ctgggcaccc aggcatcatc ccaccacatg ccactctcgt cttcgatgtg    480

gagcttctaa aactggaatg acaggaatgg cctcctccct tagctccctg ttcttggatc    540

tgccatggag ggatctggtg cctccagaca tgtgcacatg aatccatatg gagcttttcc    600

tgatgttcca ctccactttg tatagacatc tgccctgact gaatgtgttc tgtcactcag    660

ctttgcttcc gacacctctg tttcctcttc ccctttctcc tcgtatgtgt gtttacctaa    720

actatatgcc ataaacctca agttattcat tttattttgt tttcattttg gggtgaagat    780

tcagtttcag tcttttggat ataggtttcc aattaagtac atggtcaagt attaacagca    840

caagtggtag gttaacatta gaataggaat tggtgttggg gggggggttt gcaagaatat    900

tttattttaa ttttttggat gaaattttta tctattatat attaaacatt cttgctgctg    960

cgctgcaaag ccatagcaga tttgaggcgc tgttgaggac tgaattactc tccaagttga   1020

gagatgtctt tgggttaaat taaaagccct acctaaaact gaggtgggga tggggagagc   1080

ctttgcctcc accattccca cccaccctcc ccttaaaccc tctgcctttg aaagtagatc   1140

atgttcactg caatgctgga cactacaggt atctgtccct gggccagcag ggacctctga   1200

agccttcttt gtggcctttt ttttttttca tcctgtggtt tttctaatgg actttcagga   1260

attttgtaat ctcataactt tccaagctcc accacttcct aaatcttaag aactttaatt   1320

gacagtttca attgaaggtg ctgtttgtag acttaacacc cagtgaaagc ccagccatca   1380

tgacaaatcc ttgaatgttc tcttaagaaa atgatgctgg tcatcgcagc ttcagcatct   1440

cctgtttttt gatgcttggc tccctctgct gatctcagtt tcctggcttt tcctccctca   1500

gccccttctc acccctttgc tgtcctgtgt agtgatttgg tgagaaatcg ttgctgcacc   1560

cttcccccag caccatttat gagtctcaag ttttattatt gcaataaaag tgctttatgc   1620

cggcttttct cagaaaaaaa aaa                                           1643


<210>  991
<211>  839
<212>  DNA
<213>  Homo sapiens

<400>  991
agacgttctt cgccgagagt cgtcggggtt tcctgcttca acagtgcttg gacggaaccc     60

ggcgctcgtt ccccaccccg gccgccgccg ccgcctctcc ttagtcgccg ccatgacgac    120

cgcgtccacc tcgcaggtgc gccagaacta ccaccaggac tcagaggccg ccatcaaccg    180

ccagatcaac ctggagctct acgcctccta cgtttacctg tccatgtctt actactttga    240

ccgcgatgat gtggctttga agaactttgc caaatacttt cttcaccaat ctcatgagga    300

gagggaacat gctgagaaac tgatgaagct gcagaaccaa cgaggtggcc gaatcttcct    360

tcaggatatc aaggaaccag actgtgatga ctgggagagc gggcagaatg caatggagtg    420

tgcattacat ttggaaaaaa atgtgaatca gtcactactg gaactgcaca aactggccac    480

tgacaaaaat gacccccatt tgtgtgactt cattgagaca cattacctga atgagcaggt    540

gaaagccatc aaagaattgg gtgaccacgt gaccaacttg cgcaagatgg gagcgcccga    600

atctggcttg gcggaatatc tctttgacaa gcacaccctg ggagacagtg ataatgaaag    660

ctaagcctcg ggctaatttc cccatagccg tggggtgact tccctggtca ccaaggcagt    720

gcatgcatgt tggggtttcc tttacctttt ctataagttg taccaaaaca tccacttaag    780

ttctttgatt tgtaccattc cttcaaataa agaaatttgg tacccaaaaa aaaaaaaaa     839


<210>  992
<211>  1421
<212>  DNA
<213>  Homo sapiens

<400>  992
gcctcaagac cttgggctgg gactggctga gcctggcggg aggcggggtc cgagtcaccg     60

cctgccgccg cgcccccggt ttctataaat tgagcccgca gcctcccgct tcgctctctg    120

ctcctcctgt tcgacagtca gccgcatctt cttttgcgtc gccagccgag ccacatcgct    180

cagacaccat ggggaaggtg aaggtcggag tcaacggatt tggtcgtatt gggcgcctgg    240

tcaccagggc tgcttttaac tctggtaaag tggatattgt tgccatcaat gaccccttca    300

ttgacctcaa ctacatggtt tacatgttcc aatatgattc cacccatggc aaattccatg    360

gcaccgtcaa ggctgagaac gggaagcttg tcatcaatgg aaatcccatc accatcttcc    420

aggagcgaga tccctccaaa atcaagtggg gcgatgctgg cgctgagtac gtcgtggagt    480

ccactggcgt cttcaccacc atggagaagg ctggggctca tttgcagggg ggagccaaaa    540

gggtcatcat ctctgccccc tctgctgatg cccccatgtt cgtcatgggt gtgaaccatg    600

agaagtatga caacagcctc aagatcatca gcaatgcctc ctgcaccacc aactgcttag    660

cacccctggc caaggtcatc catgacaact ttggtatcgt ggaaggactc atgaccacag    720

tccatgccat cactgccacc cagaagactg tggatggccc ctccgggaaa ctgtggcgtg    780

atggccgcgg ggctctccag aacatcatcc ctgcctctac tggcgctgcc aaggctgtgg    840

gcaaggtcat ccctgagctg aacgggaagc tcactggcat ggccttccgt gtccccactg    900

ccaacgtgtc agtggtggac ctgacctgcc gtctagaaaa acctgccaaa tatgatgaca    960

tcaagaaggt ggtgaagcag gcgtcggagg gccccctcaa gggcatcctg ggctacactg   1020

agcaccaggt ggtctcctct gacttcaaca gcgacaccca ctcctccacc tttgacgctg   1080

gggctggcat tgccctcaac gaccactttg tcaagctcat ttcctggtat gacaacgaat   1140

ttggctacag caacagggtg gtggacctca tggcccacat ggcctccaag gagtaagacc   1200

cctggaccac cagccccagc aagagcacaa gaggaagaga gagaccctca ctgctgggga   1260

gtccctgcca cactcagtcc cccaccacac tgaatctccc ctcctcacag ttgccatgta   1320

gaccccttga agaggggagg ggcctaggga gccgcacctt gtcatgtacc atcaataaag   1380

taccctgtgc tcaaccagtt aaaaaaaaaa aaaaaaaaaa a                       1421


<210>  993
<211>  2909
<212>  DNA
<213>  Homo sapiens

<400>  993
gcactgagcc ggctcaggca gagacgcggc accatggcta gcaagaaagt ctgcattgta     60

ggctccggga actggggctc agccatcgcc aagatcgtgg gtggcaatgc agcccagctg    120

gcacagtttg acccacgggt gaccatgtgg gtatttgagg aagacattgg aggcaaaaag    180

ctgactgaga tcatcaacac gcagcatgag aatgtcaaat acctgccagg gcacaagttg    240

cccccaaatg tggtggctgt cccagatgtg gtccaggctg cagaggatgc tgacatcctg    300

atctttgtgg tgccccatca gttcatcggc aagatctgtg accagctcaa gggccatctg    360

aaggcaaacg ccactggcat atctcttatt aagggggtag acgagggccc caatgggctg    420

aagctcatct cggaagtgat tggggagcgc ctcggcatcc ccatgagtgt gctgatgggg    480

gccaacattg ccagcgaggt ggctgatgag aagttctgtg agacaaccat tggctgcaag    540

gacccggccc agggacaact cctgaaagag ctgatgcaga caccaaactt ccgtatcaca    600

gtggtgcaag aggtggacac agtagagatc tgtggagcct taaagaatgt agtggccgtg    660

ggggctggct tctgtgatgg cctgggcttt ggcgacaaca ccaaggcggc agtgatccgg    720

ctgggactca tggagatgat agccttcgcc aagctcttct gcagtggccc tgtgtcctct    780

gccaccttct tggagagctg tggtgttgct gacctgatca ctacctgcta tggagggcgg    840

aaccggaaag tggctgaggc ctttgcgcgt acaggaaagt ccattgagca gctggagaaa    900

gagttgctga atgggcagaa actgcagggg cccgagacag cccgggagct atacagcatc    960

ctccagcaca agggcctggt agacaagttt cccttgttca tggctgtgta caaggtgtgc   1020

tacgagggcc agccagtggg tgaattcatc cactgcctgc agaatcatcc agaacatatg   1080

tgagtggggc cagggcccag gccaggccgc ttttttaccc cagcggagac cagcagaagc   1140

ctggggtacc tagtcaccag gatctccagg actcccaggg agcagagtct tctcatcttt   1200

tcactggagg acaggaggct atggggccca gctacgcacc tggagatcct gaactgtcaa   1260

gccactggca gcctcatgcc accacatttg ccagaaatgc agttgccctg tccctctcca   1320

gatgtggggc tttctccata tcctctggga ggggtggaat caagccccag tgctgcctgc   1380

ttggtggcgg gggtgatgta tgtggagaag ggttggggga gaggccggta gggcaggggc   1440

tgctagtggc tgtctcacat acaccagtaa tcctgttaaa gggctgaaga agtatcttag   1500

ccacaggagc gatgaggcaa ggattgtcag ggaggggtct gggcttctga gctgatgcag   1560

gccccaagga cccctttgct gacctctgcc aggacccaca cagcttcgat ggatctcagt   1620

gtttgttaac aaaatacaaa gatctcaaac aaaccccttt tagcttctcc tagcaacatc   1680

tgtgtcctca gaaacctctg gttctccccc ttccccctcc cccaggctgc cctggcaccc   1740

aaattgctgc catgctggca tctgtagctc ggtggcttga cattctcccc agggacttcc   1800

cggttcctag ttctttgcca gctcctcccc actctgtgcg acctttccaa gccttccctc   1860

accctccccg ccagcaccct ctttggggag caggaactta atctgctgac agagctacac   1920

ctttcataac aggctcagat cactcagctc cctgtgacct ttgtattcac ccaggcttcc   1980

ttctcagtag ctctagctgg gggaggtgtc agctgggccc ctcctgtgct atctccccag   2040

aggacatccc tgactccacc cctttcttcc tcccaaactc tgcacctctt cctcagctgc   2100

tccagaccgg ccagggtaac cagctaacca tgcctggcat ctggaagcca gcaggccaga   2160

gggtggccca aaggctgatg aacggtaggg aagggtgagc agattcctat gttggtgggc   2220

accaatattc caagggcagc tctctttgct gaatgagggc cttctcgtga ggtactgaca   2280

acaccagcaa ctcgagagct gggaaactca aggaggagga agaaaatcaa aaccacccta   2340

ctccctgggg tgaggaaaga acaggagggg aggaggagga gtgtgctctg cacttgcctt   2400

gctccagcat ggggtggcag cagaggaatg tcacaggtca gcagcctagg cctccagcta   2460

taaatagtcc ggagggcccg agaggctccc gcccgtccag cagggctgtc agcttcctgt   2520

gtggcagcac ctggcacact ggctctggcc agcattatgc taaaaccctg ttactctcca   2580

atgaaccagg gaggcgggct cctctctgcg cctatccctt gagaattctg tcttaccagt   2640

gaagggtggg gctgcccaga tcaggcagca ggagtgaggg gcacagtcac cccaggcctt   2700

gctgagccca ggtctgggta ctgagtgtcc agagctgcct ccccaggagg ttaaggtggg   2760

ggcaaagggg aagcttcaag cactttgcct acttttgttc actccccagt gcactgtgac   2820

tcaggccttc ccatcaggcc tatttgtcta cccaataaag cgtgtttttt ccagaaaaaa   2880

aaaaaaaaaa aaaaaaaaaa aaaaaaaaa                                     2909


<210>  994
<211>  2710
<212>  DNA
<213>  Homo sapiens

<400>  994
gctcatcttc ctaccagaaa tcggcaagtc actgaccctc gtcccgcccc cgccattccc     60

cgcctcctcc tgtcccgcag tcggcgtcca gcggctctgc ttgttcgtgt gtgtgtcgtt    120

gcaggcctta ttcatgggct caccgctgag gttcgacggg cgggtggtac tggtcaccgg    180

cgcgggggca ggattgggcc gagcctatgc cctggctttt gcagaaagag gagcgttagt    240

tgttgtgaat gatttgggag gggacttcaa aggagttggt aaaggctcct tagctgctga    300

taaggttgtt gaagaaataa gaaggagagg tggaaaagca gtggccaact atgattcagt    360

ggaagaagga gagaaggttg tgaagacagc cctggatgct tttggaagaa tagatgttgt    420

ggtcaacaat gctggaattc tgagggatcg ttcctttgct aggataagtg atgaagactg    480

ggatataatc cacagagttc atttgcgggg ttcattccaa gtgacacggg cagcatggga    540

acacatgaag aaacagaagt atggaaggat tattatgact tcatcagctt caggaatata    600

tggcaacttt ggccaggcca attatagtgc tgcaaagttg ggtcttctgg gccttgcaaa    660

ttctcttgca attgaaggca ggaaaagcaa cattcattgt aacaccattg ctcctaatgc    720

gggatcacgg atgactcaga cagttatgcc tgaagatctt gtggaagccc tgaagccaga    780

gtatgtggca cctcttgtcc tttggctttg tcacgagagt tgtgaggaga atggtggctt    840

gtttgaggtt ggagcaggat ggattggaaa attacgctgg gagcggactc ttggagctat    900

tgtaagacaa aagaatcacc caatgactcc tgaggcagtc aaggctaact ggaagaagat    960

ctgtgacttt gagaatgcca gcaagcctca gagtatccaa gaatcaactg gcagtataat   1020

tgaagttctg agtaaaatag attcagaagg aggagtttca gcaaatcata ctagtcgtgc   1080

aacgtctaca gcaacatcag gatttgctgg agctattggc cagaaactcc ctccattttc   1140

ttatgcttat acggaactgg aagctattat gtatgccctt ggagtgggag cgtcaatcaa   1200

ggatccaaaa gatttgaaat ttatttatga aggaagttct gatttctcct gtttgcccac   1260

cttcggagtt atcataggtc agaaatctat gatgggtgga ggattagcag aaattcctgg   1320

actttcaatc aactttgcaa aggttcttca tggagagcag tacttagagt tatataaacc   1380

acttcccaga gcaggaaaat taaaatgtga agcagttgtt gctgatgtcc tagataaagg   1440

atccggtgta gtgattatta tggatgtcta ttcttattct gagaaggaac ttatatgcca   1500

caatcagttc tctctctttc ttgttggctc tggaggcttt ggtggaaaac ggacatcaga   1560

caaagtcaag gtagctgtag ccatacctaa tagacctcct gatgctgtac ttacagatac   1620

cacctctctt aatcaggctg ctttgtaccg cctcagtgga gactggaatc ccttacacat   1680

tgatcctaac tttgctagtc tagcaggttt tgacaagccc atattacatg gattatgtac   1740

atttggattt tctgccaggc gtgtgttaca gcagtttgca gataatgatg tgtcaagatt   1800

caaggcaatt aaggctcgtt ttgcaaaacc agtatatcca ggacaaactc tacaaactga   1860

gatgtggaag gaaggaaaca gaattcattt tcaaaccaag gtccaagaaa ctggagacat   1920

tgtcatttca aatgcatatg tggatcttgc accaacatct ggtacttcag ctaagacacc   1980

ctctgagggc gggaagcttc agagtacctt tgtatttgag gaaataggac gccgcctaaa   2040

ggatattggg cctgaggtgg tgaagaaagt aaatgctgta tttgagtggc atataaccaa   2100

aggcggaaat attggggcta agtggactat tgacctgaaa agtggttctg gaaaagtgta   2160

ccaaggccct gcaaaaggtg ctgctgatac aacaatcata ctttcagatg aagatttcat   2220

ggaggtggtc ctgggcaagc ttgaccctca gaaggcattc tttagtggca ggctgaaggc   2280

cagagggaac atcatgctga gccagaaact tcagatgatt cttaaagact acgccaagct   2340

ctgaagggca cactacacta ttaataaaaa tggaatcatt aaatactctc ttcacccaaa   2400

tatgcttgat tattctgcaa aagtgattag aactaagatg caggggaaat tgcttaacat   2460

tttcagatat cagataactg cagattttca ttttctacta atttttcatg tatcattatt   2520

tttacaagga actatatata agctagcaca taattatcct tctgttctta gatctgtatc   2580

ttcataataa aaaattttgc ccaagtcctg tttccttaga atttgtgata gcattgataa   2640

gttgaaagga aaattaaatc aataaaggcc tttgatacct ttgttaaaaa aaaaaaaaaa   2700

aaaaaaaaaa                                                          2710


<210>  995
<211>  2418
<212>  DNA
<213>  Homo sapiens

<400>  995
agcgggtctc aaatttgcag ggagggacgg ggtggggggt ggggggaccc cggttgtgca     60

gtttgatatt gagggagccc ccacctactc gctggggctg cgtaatctgg acgtttccaa    120

actgaagcga aggcgtcggg agactaggcc tcagagaacc atggctactg ccaagggaat    180

cgccataggc atcgacctgg gcaccaccta ctcctgtgtg ggggtgttcc agcacggcaa    240

ggtggagatc atcgccaacg accagggcaa ccgcaccacc cccagctacg tggccttcac    300

agacaccgag cggctcattg gggatgcggc caagaaccag gtagcaatga atccccagaa    360

cactgttttt gatgctaaac gtctgatcgg caggaaattt aatgatcctg ttgtacaagc    420

agatatgaaa ctttggcctt ttcaagtgat taatgaagga ggcaagccca aagtccttgt    480

gtcctacaaa ggggagaata aagctttcta ccctgaggaa atctcttcga tggtattgac    540

taagttgaag gagactgctg aggccttttt gggccaccct gtcaccaatg cagtgattac    600

cgtgccagcc tatttcaatg actctcaacg tcaggctact aaggatgcag gtgtgattgc    660

tggacttaat gtgctaagaa tcatcaatga gcccacggct gctgccattg cctatggttt    720

agataaagga ggtcaaggag aacgacatgt cctgattttt gatctgggtg gaggcacatt    780

tgatgtgtca attctgacca tagatgatgg gatttttgag gtaaaggcca ctgctgggga    840

cactcacctg ggtggggagg actttgacaa caggcttgtg agccacttcg tggaggagtt    900

caagaggaaa cacaaaaagg acatcagcca gaacaagcga gccgtgaggc ggctgcgcac    960

cgcctgcgag agggccaaga ggaccctgtc gtccagcacc caggccaacc tagaaattga   1020

ttcactttat gaaggcattg acttctatac atccatcacc agagctcgat ttgaagagtt   1080

gtgtgcagac ctgtttaggg gtaccctgga gcctgtagaa aaagcgcttc gggatgccaa   1140

gatggataag gctaaaatcc atgacattgt tttagtaggg ggctccaccc gcatccccaa   1200

ggtgcagcgg ctgcttcagg actacttcaa tggacgtgat ctcaacaaga gcatcaaccc   1260

tgatgaggcc gtagcatatg gggctgcggt acaagcagcc atcctgatgg gggacaagtc   1320

tgagaaggta caggacctgc tgctgctgga cgtggctccc ctgtccctgg ggctggagac   1380

ggctgggggc gtgatgactg ccttgatgaa gcgcaactcc accatcccca ccaagcagac   1440

acagattttc accacctact ctgacaacca acccggggtg ctgatccagg tgtatgaggg   1500

cgagagggcc atgacaaagg acaacaacct gctggggcgg tttgacctga ctggaatccc   1560

tccagcaccc aggggagttc ctcagatcga ggtgacgttt gacattgatg ccaatggtat   1620

tctcaatgtc acagccatgg acaagagcac cggcaaggtg aacaagatca ccatcgccaa   1680

tgacaagggc cgcctgagca aggaggagat tgagcgcatg gttctggatg ctgagaaata   1740

taaagctgaa gatgaggtcc agagggagaa aattgctgca aagaatgcct tagaatccta   1800

tgcttttaac atgaagagtg ttgtgagtga tgaaggtttg aagggcaaga ttagtgagtc   1860

tgataaaaat aaaatattgg ataaatgcaa cgagctcctt tcgtggctgg aggtcaatca   1920

actggcagag aaagatgagt ttgatcataa gagaaaggaa ttggagcaga tgtgtaaccc   1980

tatcatcaca aaactctacc aaggaggatg cactgggcct gcctgcggaa cagggtatgt   2040

gcctggaagg cctgccacag gccccacaat tgaagaagta gattaattct ttttagaact   2100

gaagcatcct aggatgcctc tacatgtatt tcattcccct catcttcaaa catcattatt   2160

attcttgacc agacctgaat ctaagttacc atcccttgga aattctggag aaggagtctc   2220

atgcaccacc tatcacactc cctcacatcc tgtttctgac tttggaatgg actcaggaaa   2280

actaggcccc tctttaaacc gtgtgatgta tttgaatgtc tgttatttcc agccacccta   2340

acattcttct tcctgtgtgg atgcttattt gtcaatcagt aaatttgttc gtaaagaaaa   2400

ttaaaaaaaa aaaaaaaa                                                 2418


<210>  996
<211>  2259
<212>  DNA
<213>  Homo sapiens

<400>  996
ctcttgggtt ttttgtggct tccttcgtta ttggagccag gcctacacgc cagcaaccat     60

gtccaaggga cctgcagttg gtattgatct tggcaccacc tactcttgtg tgggtgtttt    120

ccagcacgga aaagtcgaga taattgccaa tgatcaggga aaccgaacca ctccaagcta    180

tgtcgccttt acggacactg aacggttgat cggtgatgcc gcaaagaatc aagttgcaat    240

gaaccccacc aacacagttt ttgatgccaa acgtctgatt ggacgcagat ttgatgatgc    300

tgttgtccag tctgatatga aacattggcc ctttatggtg gtgaatgatg ctggcaggcc    360

caaggtccaa gtagaataca agggagagac caaaagcttc tatccagagg aggtgtcttc    420

tatggttctg acaaagatga aggaaattgc agaagcctac cttgggaaga ctgttaccaa    480

tgctgtggtc acagtgccag cttactttaa tgactctcag cgtcaggcta ccaaagatgc    540

tggaactatt gctggtctca atgtacttag aattattaat gagccaactg ctgctgctat    600

tgcttacggc ttagacaaaa aggttggagc agaaagaaac gtgctcatct ttgacctggg    660

aggtggcact tttgatgtgt caatcctcac tattgaggat ggaatctttg aggtcaagtc    720

tacagctgga gacacccact tgggtggaga agattttgac aaccgaatgg tcaaccattt    780

tattgctgag tttaagcgca agcataagaa ggacatcagt gagaacaaga gagctgtaag    840

acgcctccgt actgcttgtg aacgtgctaa gcgtaccctc tcttccagca cccaggccag    900

tattgagatc gattctctct atgaaggaat cgacttctat acctccatta cccgtgcccg    960

atttgaagaa ctgaatgctg acctgttccg tggcaccctg gacccagtag agaaagccct   1020

tcgagatgcc aaactagaca agtcacagat tcatgatatt gtcctggttg gtggttctac   1080

tcgtatcccc aagattcaga agcttctcca agacttcttc aatggaaaag aactgaataa   1140

gagcatcaac cctgatgaag ctgttgctta tggtgcagct gtccaggcag ccatcttgtc   1200

tggagacaag tctgagaatg ttcaagattt gctgctcttg gatgtcactc ctctttccct   1260

tggtattgaa actgctggtg gagtcatgac tgtcctcatc aagcgtaata ccaccattcc   1320

taccaagcag acacagacct tcactaccta ttctgacaac cagcctggtg tgcttattca   1380

ggtttatgaa ggcgagcgtg ccatgacaaa ggataacaac ctgcttggca agtttgaact   1440

cacaggcata cctcctgcac cccgaggtgt tcctcagatt gaagtcactt ttgacattga   1500

tgccaatggt atactcaatg tctctgctgt ggacaagagt acgggaaaag agaacaagat   1560

tactatcact aatgacaagg gccgtttgag caaggaagac attgaacgta tggtccagga   1620

agctgagaag tacaaagctg aagatgagaa gcagagggac aaggtgtcat ccaagaattc   1680

acttgagtcc tatgccttca acatgaaagc aactgttgaa gatgagaaac ttcaaggcaa   1740

gattaacgat gaggacaaac agaagattct ggacaagtgt aatgaaatta tcaactggct   1800

tgataagaat cagactgccg agaaggaaga atttgaacat caacagaaag agctggagaa   1860

agtttgcaac cccatcatca ccaagctgta ccagagtgca ggaggcatgc caggaggaat   1920

gcctggggga tttcctggtg gtggagctcc tccctctggt ggtgcttcct cagggcccac   1980

cattgaagag gttgattaag ccaaccaagt gtagatgtag cattgttcca cacatttaaa   2040

acatttgaag gacctaaatt cgtagcaaat tctgtggcag ttttaaaaag ttaagctgct   2100

atagtaagtt actgggcatt ctcaatactt gaatatggaa catatgcaca ggggaaggaa   2160

ataacattgc actttataaa cactgtattg taagtggaaa atgcaatgtc ttaaataaaa   2220

ctatttaaaa ttggcaccat aaacaaaaaa aaaaaaaaa                          2259


<210>  997
<211>  2568
<212>  DNA
<213>  Homo sapiens

<400>  997
accgcctctt gtttttcccg cgaaactcgg cggctgagcg tggaggttct tgtctcccct     60

ggtttgtgaa gtgcggaaaa ccagaggcgc agtcatgtcg ggattcgacg atcctggcat    120

tttctacagc gacagcttcg ggggcgacgc ccaggccgac gaggggcagg cccgcaaatc    180

gcagctgcag aggcgcttca aggagttcct gcggcagtac cgagtgggca ccgaccgcac    240

gggcttcacc ttcaaataca gggatgaact caagcggcat tacaacctgg gggagtactg    300

gattgaggtg gagatggagg atctggccag ctttgatgag gacctggccg actacttgta    360

caagcagcca gccgagcacc tgcagctgct ggaggaagct gccaaggagg tagctgatga    420

ggtgacccgg ccccggcctt ctggggagga ggtgctccag gacatccagg tcatgctcaa    480

gtcggacgcc agcccttcca gcattcgtag cctgaagtcg gacatgatgt cacacctggt    540

gaagatccct ggcatcatca tcgcggcctc tgcggtccgt gccaaggcca cccgcatctc    600

tatccagtgc cgcagctgcc gcaacaccct caccaacatt gccatgcgcc ctggcctcga    660

gggctatgcc ctgcccagga agtgcaacac agatcaggct gggcgcccca aatgcccatt    720

ggacccgtac ttcatcatgc ccgacaaatg caaatgcgtg gacttccaga ccctgaagct    780

gcaggagctg cctgatgcag tcccccacgg ggagatgccc agacacatgc agctctactg    840

cgacaggtac ctgtgtgaca aggtcgtccc tgggaacagg gttaccatca tgggcatcta    900

ctccatcaag aagtttggcc tgactaccag caggggccgt gacagggtgg gcgtgggcat    960

ccgaagctcc tacatccgtg tcctgggcat ccaggtggac acagatggct ctggccgcag   1020

ctttgctggg gccgtgagcc cccaggagga ggaggagttc cgtcgcctgg ctgccctccc   1080

aaatgtctat gaggtcatct ccaagagcat cgccccctcc atctttgggg gcacagacat   1140

gaagaaggcc attgcctgcc tgctctttgg gggctcccga aagaggctcc ctgatggact   1200

tactcgccga ggagacatca acctgctgat gctaggggac cctgggacag ccaagtccca   1260

gcttctgaag tttgtggaga agtgttctcc cattggggta tacacgtctg ggaaaggcag   1320

cagcgcagct ggactgacag cctcggtgat gagggaccct tcgtcccgga atttcatcat   1380

ggagggcgga gccatggtcc tggccgatgg tggggtcgtc tgtattgacg agtttgacaa   1440

gatgcgagaa gatgaccgtg tggcaatcca cgaagccatg gagcagcaga ccatctctat   1500

cgccaaggct gggatcacca ccaccctgaa ctcccgctgc tccgtcctgg ctgctgccaa   1560

ctcagtgttc ggccgctggg atgagacgaa gggggaggac aacattgact tcatgcccac   1620

catcttgtcg cgcttcgaca tgatcttcat cgtcaaggat gagcacaatg aggagaggga   1680

tgtgatgctg gccaagcatg tcatcactct gcacgtgagc gcactgacac agacacaggc   1740

tgtggagggc gagattgacc tggccaagct gaagaagttt attgcctact gccgagtgaa   1800

gtgtggcccc cggctgtcag cagaggctgc agagaaactg aagaaccgct acatcatcat   1860

gcggagcggg gcccgtcagc acgagaggga cagtgaccgc cgctccagca tccccatcac   1920

tgtgcggcag ctggaggcca ttgtgcgcat cgcggaagcc ctcagcaaga tgaagctgca   1980

gcccttcgcc acagaggcag atgtggagga ggccctgcgg ctcttccaag tgtccacgtt   2040

ggatgctgcc ttgtccggta ccctgtcagg ggtggagggc ttcaccagcc aggaggacca   2100

ggagatgctg agccgcatcg agaagcagct caagcgccgc tttgccattg gctcccaggt   2160

gtctgagcac agcatcatca aggacttcac caagcagaaa tacccggagc acgccatcca   2220

caaggtgctg cagctcatgc tgcggcgcgg cgagatccag catcgcatgc agcgcaaggt   2280

tctctaccgc ctcaagtgag tcgcgccgcc tcactggact catggactcg cccacgcctc   2340

gcccctcctg ccgctgcctg ccattgacaa tgttgctggg acctctgcct ccccactgca   2400

gccctcgaac ttcccaggca ccctcctttc tgccccagag gaaggagctg tagtgtcctg   2460

ctgcctctgg gcgcccgcct ctagcgcggt tctgggaagt gtgcttttgg catccgttaa   2520

taataaagcc acggtgtgtt caggtaaaaa aaaaaaaaaa aaaaaaaa                2568


<210>  998
<211>  4750
<212>  DNA
<213>  Homo sapiens

<400>  998
gagaacggtg gccggacgga gagactgcgg gtctgaggga ctggcgggcg ggcgggccga     60

gcggcgccgc cgaggccggg ctgggccgag cccaggagcg cccgggatgt agcgggccac    120

cctgccgatg ccacagcgcc cggccgcggg cggagccgga gccggagcct ggggaggcgg    180

cgggggccca gagcgcagcc cgcgcccccc gcgcggagcc aggcccgctg ccgtccccgc    240

cgcccgggcc cccggcatgc agccccggct gcggaggtga cactcacgga ccttagccac    300

cgccgccgcc atcgccacca tggacgaaca ggaggcattg aactcaatca tgaacgatct    360

ggtggccctc cagatgaacc gacgtcaccg gatgcctgga tatgagacca tgaagaacaa    420

agacacaggt cactcaaata ggcagagtga cgtcagaatc aagttcgagc acaacgggga    480

gaggcgaatt atagcgttca gccggcctgt gaaatatgaa gatgtggagc acaaggtgac    540

aacagtattt ggacaacctc ttgatctaca ttacatgaac aatgagctct ccatcctgct    600

gaaaaaccaa gatgatcttg ataaagcaat tgacatttta gatagaagct caagcatgaa    660

aagccttagg atattgctgt tgtcccagga cagaaaccat aacagttcct ctccccactc    720

tggggtgtcc agacaggtgc ggatcaaggc ttcccagtcc gcaggggata taaatactat    780

ctaccagccc cccgagccca gaagcaggca cctctctgtc agctcccaga accctggccg    840

aagctcacct ccccctggct atgttcctga gcggcagcag cacattgccc ggcaggggtc    900

ctacaccagc atcaacagtg agggggagtt catcccagag accagcgagc agtgcatgct    960

ggatcccctg agcagtgcag aaaattcctt gtctggaagc tgccaatcct tggacaggtc   1020

agcagacagc ccatccttcc ggaaatcacg aatgtcccgt gcccagagct tccctgacaa   1080

cagacaggaa tactcagatc gggaaactca gctttatgac aaaggggtca aaggtggaac   1140

ctacccccgg cgctaccacg tgtctgtgca ccacaaggac tacagtgatg gcagaagaac   1200

atttccccga atacggcgtc atcaaggcaa cttgttcacc ctggtgccct ccagccgctc   1260

cctgagcaca aatggcgaga acatgggtct ggctgtgcaa tacctggacc cccgtgggcg   1320

cctgcggagt gcggacagcg agaatgccct ctctgtgcag gagaggaatg tgccaaccaa   1380

gtctcccagt gcccccatca actggcgccg gggaaagctc ctgggccagg gtgccttcgg   1440

cagggtctat ttgtgctatg acgtggacac gggacgtgaa cttgcttcca agcaggtcca   1500

atttgatcca gacagtcctg agacaagcaa ggaggtgagt gctctggagt gcgagatcca   1560

gttgctaaag aacttgcagc atgagcgcat cgtgcagtac tatggctgtc tgcgggaccg   1620

cgctgagaag accctgacca tcttcatgga gtacatgcca gggggctcgg tgaaagacca   1680

gttgaaggct tacggtgctc tgacagagag cgtgacccga aagtacacgc ggcagatcct   1740

ggagggcatg tcctacctgc acagcaacat gattgttcac cgggacatta agggagccaa   1800

catcctccga gactctgctg ggaatgtaaa gctgggggac tttggggcca gcaaacgcct   1860

gcagacgatc tgtatgtcgg ggacgggcat gcgctccgtc actggcacac cctactggat   1920

gagccctgag gtgatcagcg gcgagggcta tggaaggaaa gcagacgtgt ggagcctggg   1980

ctgcactgtg gtggagatgc tgacagagaa accaccgtgg gcagagtatg aagctatggc   2040

cgccatcttc aagattgcca cccagcccac caatcctcag ctgccctccc acatctctga   2100

acatggccgg gacttcctga ggcgcatttt tgtggaggct cgccagagac cttcagctga   2160

ggagctgctc acacaccact ttgcacagct catgtactga gctctcacgg ccacacagct   2220

gccggtcgcc ctttgctgca tggcaggggg ctgctgctgg gctcagtgaa gttgctgctt   2280

ctcccaggca aggctgtgga ccatggagtg gcagcccagc cagcgtcggt ctgtgcccct   2340

tccgccactg gggctcagag ccggggtggg gtggctgcag cctcaggact gggagccccc   2400

agcctgtcag atccaggagc tccagtgtcc tgagctcagc gtggaggggt aggggctggg   2460

aacagtgtgc aaggcagccg tgggccccac cctcggggat gtgtcctgac actgcaattg   2520

gcaccgaagc ccagagggtc tgggggcaca agactgacgc cagggtatga agagtgttat   2580

tttcattcaa agtgttattt tgtttttcct tccaatgtct ggagaccacc agggcatctc   2640

tgggctggat gagctcccac aagcctgagg gaaaggccag cactcgctag cagtggcagg   2700

cagaggccca ggctgccgtc ccctagagtc ccaggttggc tctgccagtc ctgtccttta   2760

ccaaagatga atgaagcaaa tgtcatgctg ccttattcag ggaaggagga gcctgtcctg   2820

cctgtggcca tgaccctgcc tctcccaggc aggggcccgc gatgtggaac tgctgccact   2880

gaggggggat ccagttttgt caatgcagtt gtctctgttt tacaagttgg agtcactctt   2940

atgctgtacc cagtttctaa actggagact gtgtgtgccc tctgggctct gagtacccct   3000

gctttgggct tgggcctagg ctgcattgaa aagagctgaa ggttgtggcc tttgcgctcc   3060

tggcccagcc tttgttcccc actggagcag aaggggagat ggacgacacg gtcggggcat   3120

ctggcctggc cagtgccctg atcccagaga gcccgaggag gtgtctcagg ctgcctgagt   3180

cgtgacctgc taggccagag cccactccat ctggtagaag ggaaagccca tatgctacca   3240

ccagctgtgt ccaaaaccgc cagctctgtt cttcctcagc cagcctcgcc catccccttg   3300

aggtctcagc ccctttccct tgtagctcct cccctggagg gggaatggca gcaggggttg   3360

gggaaacagc atctccaagc agcttagagt tggccatatt tacctcagcc tgggcgctgg   3420

tcctttcttc cggcccctcc cctccaaaat gtgcctattg ctagagctcc tccctctcaa   3480

cacccagttt ccttgggagt tgtcattaaa ggaaaaaaaa aaaaaaaaaa gccagtgccc   3540

agggatgggc atctccaggg agctggggat tagtgccagg cagccctgcc agccatgcct   3600

acatccccat gggcacagaa caagccaaag ccttcgttgt atgttgacga tgcactttta   3660

tgaatgtagt ttctatcgct gtttttagcc ttttcacatc atgtaatgtg aggccttgta   3720

cttgttaatt tatatctcag atcatatttg atggttttta tatatatcaa ttctagactg   3780

ttacaggtga cggacgcctc aagagagaga agagaaaatg aaagcagctg gttttgcaga   3840

agtgtgtgtc gcatgcgcca gttgggcctg gaccctcctg tgtccatccc tgttccccca   3900

ggggctctat cagcccctgt accccacact gccctctgaa gacaacacag gctcctgctt   3960

ccacctcggc ccttgcccag ggtggggcct ggccctcatc ttgaccaaag ctgctgtgtg   4020

gcagctcggc ctctctacga ccccatcttg gtggctgcac actcttcctg gcccgcaccc   4080

ccatccccag tccctgttcc ccaagaggat acagagcacg gtgctggctg actcaactgt   4140

gcgtcccagg ttcagggtct tacagagctc caccccctgg ggtcttacct cactgggaat   4200

gtgttttgaa aatgaatttg aagacaagcc aacaaaccct gcactccaaa aaagcaaaac   4260

agaccctaat ttttttgtgc caaaaactgt ggacatgctg gctcagcatc ctcaggacca   4320

agttgttgct taatttattg ttttttaata actaatccag ataaaaagtt gtggggcttc   4380

agggtgacct gggcccaaag gttctgaagg gcagttcctg gcagccccag gcttgctgtg   4440

ggaaggggcc gtgccgtcac tttctcatca ttccatgggg tgtgtctgcc tgggccaact   4500

ctgcatggag aggccagggc tggggacagt ccgcactctg ccaccctcct gccccttcca   4560

cccaccccag ctctatgtct gtgtctgaat tgtggatcgt gcagccatgg ttattgtgga   4620

actgtggaac ctgcagccat agttatttga ctatatcttg accgagggct tgcagtgcaa   4680

agccaggcca gtgttgcgca ttacttacaa taaaagggat catttatatc agaaaaaaaa   4740

aaaaaaaaaa                                                          4750


<210>  999
<211>  4520
<212>  DNA
<213>  Homo sapiens

<400>  999
acagcgtcct gcgcgcatgc gcttcgcagc ttctctcgcc gccgcgcccc cagctgctct     60

ggttacggtt ggtgtttgcg aattctctgc ggcaccttct tcgctgaact ccaccgtcag    120

ttccataggc gcgcgcccgc gtcacgtggg ccgaggttcc ggcgcggctg ctggccggcg    180

gctgagccgg gagaaaggag ctgcggccac cgttcgccct acttctgcgc ctcggggcgg    240

gcgcgccggt aaaaatggcg aaatgggggt aggcggcgct ggacctgaag agatggggcg    300

cgcaggtggg gcggttgtca gagccccctg acgtgggcgc cgggctttta tcggcgattt    360

gatctggcga cctcgggccg gcgcctaaga ggtcagactg cggagcctgc gggtcgccag    420

cggccccgcc gagagccgga ggcaatggat gaacagagcg tggagagcat tgctgaggtt    480

ttccgatgtt tcatttgtat ggagaaattg cgggatgcac gcctgtgtcc tcattgctcc    540

aaactgtgtt gtttcagctg tattaggcgc tggctgacag agcagagagc tcaatgtcct    600

cattgccgtg ctccactcca gctacgagaa ctagtaaatt gtcgttgggc agaagaagta    660

acacaacagc ttgatactct tcaactctgc agtctcacca aacatgaaga aaatgaaaag    720

gacaaatgtg aaaatcacca tgaaaaactt agtgtatttt gctggacttg taagaagtgt    780

atctgccatc agtgtgcact ttggggagga atgcatggcg gacatacctt taaacctttg    840

gcagaaattt atgagcaaca cgtcactaaa gtgaatgaag aggtagccaa acttcgtcgg    900

cgtctcatgg aactgatcag cttagttcaa gaagtggaaa ggaatgtaga agctgtaaga    960

aatgcaaaag atgagcgtgt tcgggaaatt aggaatgcag tggagatgat gattgcacgg   1020

ttagacacac agctgaagaa taagcttata acactgatgg gtcagaagac atctctaacc   1080

caagaaacag agcttttgga atccttactt caggaggtgg agcaccagtt gcggtcttgt   1140

agtaagagtg agttgatatc taagagctca gagatcctta tgatgtttca gcaagttcat   1200

cggaagccca tggcatcttt tgttaccact cctgttccac cagactttac cagtgaatta   1260

gtgccatctt acgattcagc tacttttgtt ttagagaatt tcagcacttt gcgtcagaga   1320

gcagatcctg tttacagtcc acctcttcaa gtttcaggac tttgctggag gttaaaagtt   1380

tacccagatg gaaatggagt tgtgcgaggt tactacttat ctgtgtttct ggagctctca   1440

gctggcttgc ctgaaacttc taaatatgaa tatcgtgtag agatggttca ccagtcctgt   1500

aatgatccta caaaaaatat cattcgagaa tttgcatctg actttgaagt tggagaatgc   1560

tggggctata atagattttt ccgtttggac ttactcgcaa atgaaggata cttgaatcca   1620

caaaatgata cagtgatttt aaggtttcag gtacgttcac caactttctt tcaaaaatcc   1680

cgggaccagc attggtacat tactcagttg gaagctgcac agactagtta tatccaacaa   1740

ataaacaacc ttaaagagag acttactatt gagctgtctc gaactcagaa gtcaagagat   1800

ttgtcaccac cagataacca tcttagcccc caaaatgatg atgctctgga gacacgagct   1860

aagaagtctg catgctctga catgcttctc gaaggtggtc ctactacagc ttctgtaaga   1920

gaggccaaag aggatgaaga agatgaggag aagattcaga atgaagatta tcatcacgag   1980

ctttcagatg gagatctgga tctggatctt gtttatgagg atgaagtaaa tcagctcgat   2040

ggcagcagtt cctctgctag ttccacagca acaagtaata cagaagaaaa tgatattgat   2100

gaagaaacta tgtctggaga aaatgatgtg gaatataaca acatggaatt agaagaggga   2160

gaactcatgg aagatgcagc tgctgcagga cccgcaggta gtagccatgg ttatgtgggt   2220

tccagtagta gaatatcaag aagaacacat ttatgctccg ctgctaccag tagtttacta   2280

gacattgatc cattaatttt aatacatttg ttggacctta aggaccggag cagtatagaa   2340

aatttgtggg gcttacagcc tcgcccacct gcttcacttc tgcagcccac agcatcatat   2400

tctcgaaaag ataaagacca aaggaagcaa caggcaatgt ggcgagtgcc ctctgattta   2460

aagatgctaa aaagactcaa aactcaaatg gccgaagttc gatgtatgaa aactgatgta   2520

aagaatacac tttcagaaat aaaaagcagc agtgctgctt ctggagacat gcagacaagc   2580

cttttttctg ctgaccaggc agctctggct gcatgtggaa ctgaaaactc tggcagattg   2640

caggatttgg gaatggaact cctggcaaag tcatcagttg ccaattgtta catacgaaac   2700

tccacaaata agaagagtaa ttcgcccaag ccagctcgat ccagtgtagc aggtagtcta   2760

tcacttcgaa gagcagtgga ccctggagaa aatagtcgtt caaagggaga ctgtcagact   2820

ctgtctgaag gctccccagg aagctctcag tctgggagca ggcacagttc tccccgagcc   2880

ttgatacatg gcagtatcgg tgatattctg ccaaaaactg aagaccggca gtgtaaagct   2940

ttggattcag atgctgttgt ggttgcagtt ttcagtggct tgcctgcggt tgagaaaagg   3000

aggaaaatgg tcaccttggg ggctaatgct aaaggaggtc atctggaagg actgcagatg   3060

actgatttgg aaaataattc tgaaactgga gagttacagc ctgtactacc tgaaggagct   3120

tcagctgccc ctgaagaagg aatgagtagc gacagtgaca ttgaatgtga cactgagaat   3180

gaggagcagg aagagcatac cagtgtgggc gggtttcacg actccttcat ggtcatgaca   3240

cagcccccgg atgaagatac acattccagt tttcctgatg gtgaacaaat aggccctgaa   3300

gatctcagct tcaatacaga tgaaaatagt ggaaggtaat tgccaaatca agagaactga   3360

cttgcaagct accttgaccc tgaattttgc tgtagttggt gctcaaattt gtcatcagtc   3420

agataatcag atttggtctt atttcttcat tatctcgacc tgaaatagta atttggaaac   3480

tgttggaagg tggcacagtt tagtctaaga cagcagtagt acatgggaaa aacagtatgg   3540

gaagagttct ttgtaatgta aggaaataac aatgtagttc tctattaatt tagcaaattt   3600

gtacattcac aaaaggcagt ttgtctacta cagcagaagg ctggttaact gccagaaaat   3660

gtacctccag gccctgcatg ccgtcagtaa cccgcccggc attggtgctc tactgtcttt   3720

ggctagagct tagttgtgtt taaataatca tctttatatt tggggtttta attacagttc   3780

cattagtgcc tgtagattag tgaacagaaa attgctttgg aagagattct gccctgtaga   3840

cactatgtga ataactgaag taacactaga ctgaatctcc tttttggagt atgtatcttc   3900

tctcacttgt tcaagtacag gcacactgtt caaccgcatg gtatctttct gttgtgtgac   3960

ttctacaaat gtaattttaa atgaaattaa gttaacatgg attcattacg ttcctggccc   4020

tgtagacacg tgtaagatta tttaaaattc tttcattttt ttctgcctct tactatacga   4080

ctgtagtgca acaaatattt taaagccccc ttttcttctt tattttcatt agttgtacat   4140

tgatttcagt gtcaacacat ttaaagattc attcatgttg cacagtggct tacatgaacg   4200

tgaaactgtg atataaggtt ttctttcata ctcataatta gcccaaaaca gttgccaaac   4260

tttgccattg tgctcctgca tttgtgtttg agctgctata tatttgtgga aattacactg   4320

aaagttgact aagagactat tgaaaaagca tgaataatta aatatacatg tgagagacat   4380

ctcatctgct gtattttact tagtgaatat tgttcactct tccgtgtctg atgtcttgct   4440

gaatgctgtg actcatagtt tacttttgtt caaaatagtt tgcacttttt gttaataaaa   4500

tcaacttgag aaaataaaaa                                               4520


<210>  1000
<211>  2732
<212>  DNA
<213>  Homo sapiens

<400>  1000
ctttcgcctc agtctcgagc tctcgctggc cttcgggtgt acgtgctccg ggatcttcag     60

cacccgcggc cgccatcgcc gtcgcttggc ttcttctgga ctcatctgcg ccacttgtcc    120

gcttcacact ccgccgccat catggtgaag ctcgcgaagg caggtaaaaa tcaaggtgac    180

cccaagaaaa tggctcctcc tccaaaggag gtagaagaag atagtgaaga tgaggaaatg    240

tcagaagatg aagaagatga tagcagtgga gaagaggtcg tcatacctca gaagaaaggc    300

aagaaggctg ctgcaacctc agcaaagaag gtggtcgttt ccccaacaaa aaaggttgca    360

gttgccacac cagccaagaa agcagctgtc actccaggca aaaaggcagc agcaacacct    420

gccaagaaga cagttacacc agccaaagca gttaccacac ctggcaagaa gggagccaca    480

ccaggcaaag cattggtagc aactcctggt aagaagggtg ctgccatccc agccaagggg    540

gcaaagaatg gcaagaatgc caagaaggaa gacagtgatg aagaggagga tgatgacagt    600

gaggaggatg aggaggatga cgaggacgag gatgaggatg aagatgaaat tgaaccagca    660

gcgatgaaag cagcagctgc tgcccctgcc tcagaggatg aggacgatga ggatgacgaa    720

gatgatgagg atgacgatga cgatgaggaa gatgactctg aagaagaagc tatggagact    780

acaccagcca aaggaaagaa agctgcaaaa gttgttcctg tgaaagccaa gaacgtggct    840

gaggatgaag atgaagaaga ggatgatgag gacgaggatg acgacgacga cgaagatgat    900

gaagatgatg atgatgaaga tgatgaggag gaggaagaag aggaggagga agagcctgtc    960

aaagaagcac ctggaaaacg aaagaaggaa atggccaaac agaaagcagc tcctgaagcc   1020

aagaaacaga aagtggaagg cacagaaccg actacggctt tcaatctctt tgttggaaac   1080

ctaaacttta acaaatctgc tcctgaatta aaaactggta tcagcgatgt ttttgctaaa   1140

aatgatcttg ctgttgtgga tgtcagaatt ggtatgacta ggaaatttgg ttatgtggat   1200

tttgaatctg ctgaagacct ggagaaagcg ttggaactca ctggtttgaa agtctttggc   1260

aatgaaatta aactagagaa accaaaagga aaagacagta agaaagagcg agatgcgaga   1320

acacttttgg ctaaaaatct cccttacaaa gtcactcagg atgaattgaa agaagtgttt   1380

gaagatgctg cggagatcag attagtcagc aaggatggga aaagtaaagg gattgcttat   1440

attgaattta agacagaagc tgatgcagag aaaacctttg aagaaaagca gggaacagag   1500

atcgatgggc gatctatttc cctgtactat actggagaga aaggtcaaaa tcaagactat   1560

agaggtggaa agaatagcac ttggagtggt gaatcaaaaa ctctggtttt aagcaacctc   1620

tcctacagtg caacagaaga aactcttcag gaagtatttg agaaagcaac ttttatcaaa   1680

gtaccccaga accaaaatgg caaatctaaa gggtatgcat ttatagagtt tgcttcattc   1740

gaagacgcta aagaagcttt aaattcctgt aataaaaggg aaattgaggg cagagcaatc   1800

aggctggagt tgcaaggacc caggggatca cctaatgcca gaagccagcc atccaaaact   1860

ctgtttgtca aaggcctgtc tgaggatacc actgaagaga cattaaagga gtcatttgac   1920

ggctccgttc gggcaaggat agttactgac cgggaaactg ggtcctccaa agggtttggt   1980

tttgtagact tcaacagtga ggaggatgcc aaagctgcca aggaggccat ggaagacggt   2040

gaaattgatg gaaataaagt taccttggac tgggccaaac ctaagggtga aggtggcttc   2100

gggggtcgtg gtggaggcag aggcggcttt ggaggacgag gtggtggtag aggaggccga   2160

ggaggatttg gtggcagagg ccggggaggc tttggagggc gaggaggctt ccgaggaggc   2220

agaggaggag gaggtgacca caagccacaa ggaaagaaga cgaagtttga atagcttctg   2280

tccctctgct ttcccttttc catttgaaag aaaggactct ggggttttta ctgttacctg   2340

atcaatgaca gagccttctg aggacattcc aagacagtat acagtcctgt ggtctccttg   2400

gaaatccgtc tagttaacat ttcaagggca ataccgtgtt ggttttgact ggatattcat   2460

ataaactttt taaagagttg agtgatagag ctaaccctta tctgtaagtt ttgaatttat   2520

attgtttcat cccatgtaca aaaccatttt ttcctacaaa tagtttgggt tttgttgttg   2580

tttctttttt ttgttttgtt tttgtttttt ttttttttgc gttcgtgggg ttgtaaaaga   2640

aaagaaagca gaatgtttta tcatggtttt tgcttcagcg gctttaggac aaattaaaag   2700

tcaactctgg tgccagaaaa aaaaaaaaaa aa                                 2732


<210>  1001
<211>  3836
<212>  DNA
<213>  Homo sapiens

<400>  1001
actttgggtt tcgaaatgtt cgctggctgt tccgagaatc agtccgggtc acgttggtgc     60

ctctcctttc ctgttctgat tggttgctta cgtgagcgtg actactttct tgcctcatga    120

ttggctgaaa tcagtagcgt catcggcggc cgggagggcg gagggacgag ggaagtcggc    180

gagagggaga ctgggttggg ggaggggttc aggcctgttc cccgcggctg cggcagcacc    240

agggccggcc gccaccgcct ctagaacgcg gaggaggtgg gtcctgggaa gcgggatgtc    300

catcgctcca gcttggtggt gaatgctgag gagagtcact gttgctgcag tctgtgccac    360

ccggaggaag ttgtgtgagg ccgggcggga gctcgcggcg ctctggggaa tcgaaacgcg    420

gggtcggtgc gaagactctg ctgctgccag accctttcct attctggcca tgcctggaag    480

gaacaaggcg aagtctacct gcagctgccc tgacctgcag cccaatggac aggatctggg    540

cgagaacagc cgggttgccc gtctaggagc ggatgaatct gaggaagagg gacggagggg    600

gtctctcagt aatgctgggg accctgagat cgtcaagtct cccagcgacc ccaagcaata    660

ccgatacatc aaattacaga atggcttgca ggcacttctg atttcagacc taagtaatat    720

ggaaggtaaa acaggaaata caacagatga tgaagaagaa gaggaggtgg aggaagaaga    780

agaagatgat gatgaagatt ctggagctga aatagaagat gacgatgaag agggttttga    840

tgatgaagat gagtttgatg atgaacatga tgatgatctt gatactgagg ataatgaatt    900

ggaagaatta gaagagagag cagaagctag aaaaaaaact actgaaaaac agtctgcagc    960

ggctctttgt gttggagttg ggagtttcgc tgatccagat gacctgccgg ggctggcaca   1020

ctttttggag cacatggtat tcatgggtag tttgaaatat ccagatgaga atggatttga   1080

tgccttcctg aagaagcatg ggggtagtga taatgcctca actgattgtg aacgcactgt   1140

ctttcagttt gatgtccaga ggaagtactt caaggaagct cttgatagat gggcgcagtt   1200

cttcatccac ccactaatga tcagagatgc aattgaccgt gaagttgaag ctgttgatag   1260

tgaatatcaa cttgcaaggc cttctgatgc aaacagaaag gaaatgttgt ttggaagcct   1320

tgctagacct ggacatccta tgggaaaatt tttttgggga aatgctgaga cgctcaagca   1380

tgagccaaga aagaataata ttgatacaca tgctagattg agagaattct ggatgcgtta   1440

ctactcttct cattacatga ctttagtggt tcaatccaaa gaaacactgg atactttgga   1500

aaagtgggtg actgaaatct tctctcagat accaaacaat gggttaccca gaccaaactt   1560

tggccattta acggatccat ttgacacacc agcatttaac aaactttata gagttgttcc   1620

aatcagaaaa attcatgctc tgaccatcac atgggcactt cctcctcaac agcaacatta   1680

cagggtgaag ccacttcatt atatatcctg gctggttgga catgaaggca aaggcagcat   1740

tctttctttc cttaggaaaa aatgctgggc tcttgcactg tttggtggaa atggtgagac   1800

aggatttgag caaaattcta cttattcagt gttcagcatt tctattacat tgactgatga   1860

gggttatgaa catttttatg aggttgctta cactgtcttt cagtatttaa aaatgctgca   1920

gaagctaggc ccagaaaaaa gaatttttga agagattcgg aaaattgagg ataatgaatt   1980

tcattaccaa gaacagacag atccagttga gtatgtggaa aacatgtgtg agaacatgca   2040

gctgtaccca ttgcaggaca ttctcactgg agatcagctt ctttttgaat acaagccaga   2100

agtcattggt gaagccttga atcagctagt tcctcaaaaa gcaaatcttg ttttactgtc   2160

tggtgctaat gagggaaaat gtgacctcaa ggagaaatgg tttggaactc aatatagtat   2220

agaagatatt gaaaactctt gggctgaact gtggaatagt aatttcgaat taaatccaga   2280

tcttcatctt ccagctgaaa acaagtacat agccacggac tttacgttga aggctttcga   2340

ttgcccggaa acagaatacc cagttaaaat tgtgaatact ccacaaggtt gcctgtggta   2400

taagaaagac aacaaattca aaatccccaa agcatatata cgtttccatc taatttcacc   2460

gttgatacag aaatctgcag caaatgtggt cctctttgat atctttgtca atatccttac   2520

gcataacctt gcggaaccag cttatgaagc agatgtggca cagctggagt ataaactggt   2580

agctggagaa catggtttaa ttattcgagt gaaaggattt aaccacaaac tacctctact   2640

gtttcagctc attattgact acttagctga gttcaattcc acaccagctg tctttacaat   2700

gataactgag cagttgaaga agacctactt taacatcctc atcaagcccg agactttggc   2760

caaagatgta cggcttttaa tcttggaata tgcccgttgg tctatgattg acaagtacca   2820

ggctttgatg gacggccttt cccttgagtc tctgctgagc ttcgtcaaag aattcaaatc   2880

ccagctcttt gtggagggcc tggtacaagg gaatgtcaca agcacagaat ctatggattt   2940

cctgaaatat gttgttgaca aactaaactt caagcctctg gagcaggaga tgcctgtgca   3000

gttccaggtg gtagagctgc ccagtggcca ccatctatgc aaagtgaaag ctctgaacaa   3060

gggtgatgcc aactctgaag tcactgtgta ctaccagtca ggtaccagga gtctaagaga   3120

atatacgctt atggagctgc ttgtgatgca catggaagaa ccttgttttg acttccttcg   3180

aaccaagcag acccttgggt accatgtcta ccctacctgt aggaacacat ccgggattct   3240

aggattttct gtcactgtgg ggactcaggc aaccaaatac aattctgaag ttgttgataa   3300

gaagatagaa gagtttcttt ctagctttga ggagaagatt gagaacctca ctgaagaggc   3360

attcaacacc caggtcacag ctctcatcaa gctgaaggag tgtgaggata cccaccttgg   3420

ggaggaggtg gataggaact ggaatgaagt ggttacacag cagtacctct ttgaccgcct   3480

tgcccacgag attgaagcac tgaagtcatt ctcaaaatca gacctggtca actggttcaa   3540

ggcccataga gggccaggaa gtaaaatgct cagcgttcat gttgttggat atgggaagta   3600

tgaactggaa gaggatggta ccccttctag tgaggattca aattcttctt gtgaagtgat   3660

gcagctgacc tacctgccaa cctctcctct gctggcagat tgtatcatcc ccattactga   3720

tatcagggct ttcacaacaa cactcaacct tctcccctac cataaaatag tcaaataaat   3780

aaactgcagt cacgttggcc tgaagcaatg tgtattttaa aaaaaaaaaa aaaaaa       3836


<210>  1002
<211>  1561
<212>  DNA
<213>  Homo sapiens

<400>  1002
gggcttatcc cgcctgtccc gccattctcg ctagttcgat cggtagcggg agcggagagc     60

ggaccccaga gagccctgag cagccccacc gccgccgccg gcctagttac catcacaccc    120

cgggaggagc cgcagctgcc gcagccggcc ccagtcacca tcaccgcaac catgagcagc    180

gaggccgaga cccagcagcc gcccgccgcc ccccccgccg cccccgccct cagcgccgcc    240

gacaccaagc ccggcactac gggcagcggc gcagggagcg gtggcccggg cggcctcaca    300

tcggcggcgc ctgccggcgg ggacaagaag gtcatcgcaa cgaaggtttt gggaacagta    360

aaatggttca atgtaaggaa cggatatggt ttcatcaaca ggaatgacac caaggaagat    420

gtatttgtac accagactgc cataaagaag aataacccca ggaagtacct tcgcagtgta    480

ggagatggag agactgtgga gtttgatgtt gttgaaggag aaaagggtgc ggaggcagca    540

aatgttacag gtcctggtgg tgttccagtt caaggcagta aatatgcagc agaccgtaac    600

cattatagac gctatccacg tcgtaggggt cctccacgca attaccagca aaattaccag    660

aatagtgaga gtggggaaaa gaacgaggga tcggagagtg ctcccgaagg ccaggcccaa    720

caacgccggc cctaccgcag gcgaaggttc ccaccttact acatgcggag accctatggg    780

cgtcgaccac agtattccaa ccctcctgtg cagggagaag tgatggaggg tgctgacaac    840

cagggtgcag gagaacaagg tagaccagtg aggcagaata tgtatcgggg atatagacca    900

cgattccgca ggggccctcc tcgccaaaga cagcctagag aggacggcaa tgaagaagat    960

aaagaaaatc aaggagatga gacccaaggt cagcagccac ctcaacgtcg gtaccgccgc   1020

aacttcaatt accgacgcag acgcccagaa aaccctaaac cacaagatgg caaagagaca   1080

aaagcagccg atccaccagc tgagaattcg tccgctcccg aggctgagca gggcggggct   1140

gagtaaatgc cggcttacca tctctaccat catccggttt agtcatccaa caagaagaaa   1200

tatgaaattc cagcaataag aaatgaacaa aagattggag ctgaagacct aaagtgcttg   1260

ctttttgccc gttgaccaga taaatagaac tatctgcatt atctatgcag catggggttt   1320

ttattatttt tacctaaaga cgtctctttt tggtaataac aaacgtgttt tttaaaaaag   1380

cctggttttt ctcaatacgc ctttaaaggt ttttaaattg tttcatatct ggtcaagttg   1440

agatttttaa gaacttcatt tttaatttgt aataaaagtt tacaacttga ttttttcaaa   1500

aaagtcaaca aactgcaagc acctgttaat aaaggtctta aataataaaa aaaaaaaaaa   1560

a                                                                   1561


<210>  1003
<211>  1507
<212>  DNA
<213>  Homo sapiens

<400>  1003
tgggcggcgg ctgaggcgcg tgctctcgcg tggtcgctgg gtctgcgtct tcccgagcca     60

gtgtgctgag ctctccgcgt cgcctctgtc gcccgcgcct ggcctaccgc ggcactcccg    120

gctgcacgct ctgcttggcc tcgccatgcc ggtggacctc agcaagtggt ccgggccctt    180

gagcctgcaa gaagtggacg agcagccgca gcacccgctg catgtcacct acgccggggc    240

ggcggtggac gagctgggca aagtgctgac gcccacccag gttaagaata gacccaccag    300

catttcgtgg gatggtcttg attcagggaa gctctacacc ttggtcctga cagacccgga    360

tgctcccagc aggaaggatc ccaaatacag agaatggcat catttcctgg tggtcaacat    420

gaagggcaat gacatcagca gtggcacagt cctctccgat tatgtgggct cggggcctcc    480

caagggcaca ggcctccacc gctatgtctg gctggtttac gagcaggaca ggccgctaaa    540

gtgtgacgag cccatcctca gcaaccgatc tggagaccac cgtggcaaat tcaaggtggc    600

gtccttccgt aaaaagtatg agctcagggc cccggtggct ggcacgtgtt accaggccga    660

gtgggatgac tatgtgccca aactgtacga gcagctgtct gggaagtagg gggttagctt    720

ggggacctga actgtcctgg aggccccaag ccatgttccc cagttcagtg ttgcatgtat    780

aatagatttc tcctcttcct gccccccttg gcatgggtga gacctgacca gtcagatggt    840

agttgagggt gacttttcct gctgcctggc ctttataatt ttactcactc actctgattt    900

atgttttgat caaatttgaa cttcattttg gggggtattt tggtactgtg atggggtcat    960

caaattatta atctgaaaat agcaacccag aatgtaaaaa agaaaaaact ggggggaaaa   1020

agaccaggtc tacagtgata gagcaaagca tcaaagaatc tttaagggag gtttaaaaaa   1080

aaaaaaaaaa aaaaagattg gttgcctctg cctttgtgat cctgagtcca gaatggtaca   1140

caatgtgatt ttatggtgat gtcactcacc tagacaacca gaggctggca ttgaggctaa   1200

cctccaacac agtgcatctc agatgcctca gtaggcatca gtatgtcact ctggtccctt   1260

taaagagcaa tcctggaaga agcaggaggg agggtggctt tgctgttgtt gggacatggc   1320

aatctagacc ggtagcagcg ctcgctgaca gcttgggagg aaacctgaga tctgtgtttt   1380

ttaaattgat cgttcttcat gggggtaaga aaagctggtc tggagttgct gaatgttgca   1440

ttaattgtgc tgtttgcttg tagttgaata aaaatagaaa cctgaatgaa gaaaaaaaaa   1500

aaaaaaa                                                             1507


<210>  1004
<211>  2332
<212>  DNA
<213>  Homo sapiens

<400>  1004
gcacagcagc tgcacgcgcc gtggctccgg atctcttcgt ctttgcagcg tagcccgagt     60

cggtcagcgc cggaggacct cagcagccat gtcgaagccc catagtgaag ccgggactgc    120

cttcattcag acccagcagc tgcacgcagc catggctgac acattcctgg agcacatgtg    180

ccgcctggac attgattcac cacccatcac agcccggaac actggcatca tctgtaccat    240

tggcccagct tcccgatcag tggagacgtt gaaggagatg attaagtctg gaatgaatgt    300

ggctcgtctg aacttctctc atggaactca tgagtaccat gcggagacca tcaagaatgt    360

gcgcacagcc acggaaagct ttgcttctga ccccatcctc taccggcccg ttgctgtggc    420

tctagacact aaaggacctg agatccgaac tgggctcatc aagggcagcg gcactgcaga    480

ggtggagctg aagaagggag ccactctcaa aatcacgctg gataacgcct acatggaaaa    540

gtgtgacgag aacatcctgt ggctggacta caagaacatc tgcaaggtgg tggaagtggg    600

cagcaagatc tacgtggatg atgggcttat ttctctccag gtgaagcaga aaggtgccga    660

cttcctggtg acggaggtgg aaaatggtgg ctccttgggc agcaagaagg gtgtgaacct    720

tcctggggct gctgtggact tgcctgctgt gtcggagaag gacatccagg atctgaagtt    780

tggggtcgag caggatgttg atatggtgtt tgcgtcattc atccgcaagg catctgatgt    840

ccatgaagtt aggaaggtcc tgggagagaa gggaaagaac atcaagatta tcagcaaaat    900

cgagaatcat gagggggttc ggaggtttga tgaaatcctg gaggccagtg atgggatcat    960

ggtggctcgt ggtgatctag gcattgagat tcctgcagag aaggtcttcc ttgctcagaa   1020

gatgatgatt ggacggtgca accgagctgg gaagcctgtc atctgtgcta ctcagatgct   1080

ggagagcatg atcaagaagc cccgccccac tcgggctgaa ggcagtgatg tggccaatgc   1140

agtcctggat ggagccgact gcatcatgct gtctggagaa acagccaaag gggactatcc   1200

tctggaggct gtgcgcatgc agcacctgat tgcccgtgag gcagaggctg ccatctacca   1260

cttgcaatta tttgaggaac tccgccgcct ggcgcccatt accagcgacc ccacagaagc   1320

caccgccgtg ggtgccgtgg aggcctcctt caagtgctgc agtggggcca taatcgtcct   1380

caccaagtct ggcaggtctg ctcaccaggt ggccagatac cgcccacgtg cccccatcat   1440

tgctgtgacc cggaatcccc agacagctcg tcaggcccac ctgtaccgtg gcatcttccc   1500

tgtgctgtgc aaggacccag tccaggaggc ctgggctgag gacgtggacc tccgggtgaa   1560

ctttgccatg aatgttggca aggcccgagg cttcttcaag aagggagatg tggtcattgt   1620

gctgaccgga tggcgccctg gctccggctt caccaacacc atgcgtgttg ttcctgtgcc   1680

gtgatggacc ccagagcccc tcctccagcc cctgtcccac ccccttcccc cagcccatcc   1740

attaggccag caacgcttgt agaactcact ctgggctgta acgtggcact ggtaggttgg   1800

gacaccaggg aagaagatca acgcctcact gaaacatggc tgtgtttgca gcctgctcta   1860

gtgggacagc ccagagcctg gctgcccatc atgtggcccc acccaatcaa gggaagaagg   1920

aggaatgctg gactggaggc ccctggagcc agatggcaag agggtgacag cttcctttcc   1980

tgtgtgtact ctgtccagtt cctttagaaa aaatggatgc ccagaggact cccaaccctg   2040

gcttggggtc aagaaacagc cagcaagagt taggggcctt agggcactgg gctgttgttc   2100

cattgaagcc gactctggcc ctggccctta cttgcttctc tagctctcta ggcctctcca   2160

gtttgcacct gtccccaccc tccactcagc tgtcctgcag caaacactcc accctccacc   2220

ttccattttc ccccactact gcagcacctc caggcctgtt gctatagagc ctacctgtat   2280

gtcaataaac aacagctgaa gcaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa           2332


<210>  1005
<211>  1851
<212>  DNA
<213>  Homo sapiens

<400>  1005
ggccggtcag cgtcgctgcc ggtctccggc ggagacggac tctggagttt gggcggcccg     60

ggcggccact aggtactctg atattccgta ctaaacacgt ctgcaagtca agatgtcgca    120

cccgtccccc caagccaagc cctccaaccc cagtaaccct cgagtcttct ttgacgtgga    180

catcggaggg gagcgagttg gtcgaattgt cttagaattg tttgcagata tcgtacccaa    240

aactgcggaa aattttcgtg cactgtgtac aggagaaaaa ggcattggac acacgactgg    300

gaaacctctc catttcaaag gatgcccttt tcatcgaatt attaagaaat ttatgattca    360

gggtggagac ttctcaaatc agaatgggac aggtggagaa agtatttatg gtgaaaaatt    420

tgaagatgaa aatttccatt acaagcatga tcgggagggt ttactgagca tggcaaatgc    480

aggccgcaac acaaacggtt ctcagttttt tatcacaaca gttccaactc ctcatttgga    540

tgggaaacat gtggtgtttg gccaagtaat taaaggaata ggagtggcaa ggatattgga    600

aaatgtggaa gtgaaaggtg aaaaacctgc taaattgtgc gttattgcag aatgtggaga    660

attgaaggaa ggagatgacg ggggaatatt cccaaaagat ggctctggcg acagtcatcc    720

agatttccct gaggatgcgg atatagattt aaaagatgta gataaaattt tattaataac    780

agaagactta aaaaacattg gaaatacttt tttcaaatcc cagaactggg agatggctat    840

taaaaaatat gcagaagttt taagatacgt ggacagttca aaggctgtta ttgagacagc    900

agatagagcc aagctgcaac ctatagcttt aagctgtgta ctgaatattg gtgcttgtaa    960

actgaagatg tcaaattggc agggagcaat tgacagttgt ttagaggctc ttgaactaga   1020

cccatcaaat accaaagcat tgtaccgcag agctcaagga tggcaaggat taaaagaata   1080

tgatcaagca ttggctgatc ttaagaaagc tcaggggata gcaccagaag ataaagctat   1140

ccaggcagaa ttgctgaaag tcaaacaaaa gataaaggca cagaaagata aagagaaggc   1200

agtatatgca aaaatgtttg cttagaaagg attcagtttt gcttattgtg tgttgattgt   1260

ataaatgcaa taagaaaatg taaaggtttt tgtctatgaa tatgatccct aatgtgtttc   1320

ttttgacacc ttagttcctt actgtttaca gtttaggagt actgataggg gttcatgctt   1380

aataaacatg tcacaataca gtaagtaaag tggttttgtt tgtttctttg agatggagtc   1440

ttgctctgtc acccaggctg gagtgcggtg gcgcaatctc ggctcactgc atcctctgcc   1500

tcccgggttc aagcaattct cctgcctcag cttcccaagt agctgggatt acaggcacgt   1560

gccaccacgc ccagctaatt tttgtatttt tagtagagat ggggtttcac catattggtc   1620

acgtcacgtt ggtcttgaac tcctgacctt gtgatccacc ccgccttggc ctcccaaagt   1680

gctgggatta caggtgtgag ccaccgtgcc cggccaagta aaatgttttt taaaatggtt   1740

atgtgcatta ttcataaaaa ataatggtgt ccagtctttt taaacttgta aagacacatc   1800

ttattgaata aagagatgag agcttaagtt tgtaaaaaaa aaaaaaaaaa a            1851


<210>  1006
<211>  1014
<212>  DNA
<213>  Homo sapiens

<400>  1006
gttattggtt ggcagttcag ccaatgagcg ggcctgttac tagtttgcgg catcctgtgg     60

tataggggaa gcgctccggg cctggaatcc ctacgcgtcc ctttgggttt agcacgatga    120

gctcaatcgg cactgggtat gacctgtcag cctctacatt ctctcctgac ggaagagttt    180

ttcaagttga atatgctatg aaggctgtgg aaaatagtag tacagctatt ggaatcagat    240

gcaaagatgg tgttgtcttt ggggtagaaa aattagtcct ttctaaactt tatgaagaag    300

gttccaacaa aagacttttt aatgttgatc ggcatgttgg aatggcagta gcaggtttgt    360

tggcagatgc tcgttcttta gcagacatag caagagaaga agcttccaac ttcagatcta    420

actttggcta caacattcca ctaaaacatc ttgcagacag agtggccatg tatgtgcatg    480

catatacact ctacagtgct gttagacctt ttggctgcag tttcatgtta gggtcttaca    540

gtgtgaatga cggtgcgcaa ctctacatga ttgacccatc aggtgtttca tacggttatt    600

ggggctgtgc catcggcaaa gccaggcaag ctgcaaagac ggaaatagag aagcttcaga    660

tgaaagaaat gacctgccgt gatatcgtta aagaagttgc aaaaataatt tacatagtac    720

atgacgaagt taaggataaa gcttttgaac tagaactcag ctgggttggt gaattaacta    780

atggaagaca tgaaattgtt ccaaaagata taagagaaga agcagagaaa tatgctaagg    840

aatctctgaa ggaagaagat gaatcagatg atgataatat gtaacattta ctccagcatc    900

tattgtattt taaatttcta ctccagtcca atgtaactat ttagccctgg attatacata    960

ctgtccaatt ttcattaaat ttttgtctta taactattaa aaaaaaaaaa aaaa         1014


<210>  1007
<211>  972
<212>  DNA
<213>  Homo sapiens

<400>  1007
gattgcttat agaccggaag ccgggacctt aattctcttt cccatcttgc aagatggcgg     60

gtgaaaaagt tgagaagcca gatactaaag agaagaaacc cgaagccaag aaggttgatg    120

ctggtggcaa ggtgaaaaag ggtaacctca aagctaaaaa gcccaagaag gggaagcccc    180

attgcagccg caaccctgtc cttgtcagag gaattggcag gtattcccga tctgccatgt    240

attccagaaa ggccatgtac aagaggaagt actcagccgc taaatccaag gttgaaaaga    300

aaaagaagga gaaggttctc gcaactgtta caaaaccagt tggtggtgac aagaacggcg    360

gtacccgggt ggttaaactt cgcaaaatgc ctagatatta tcctactgaa gatgtgcctc    420

gaaagctgtt gagccacggc aaaaaaccct tcagtcagca cgtgagaaaa ctgcgagcca    480

gcattacccc cgggaccatt ctgatcatcc tcactggacg ccacaggggc aagagggtgg    540

ttttcctgaa gcagctggct agtggcttat tacttgtgac tggacctctg gtcctcaatc    600

gagttcctct acgaagaaca caccagaaat ttgtcattgc cacttcaacc aaaatcgata    660

tcagcaatgt aaaaatccca aaacatctta ctgatgctta cttcaagaag aagaagctgc    720

ggaagcccag acaccaggaa ggtgagatct tcgacacaga aaaagagaaa tatgagatta    780

cggagcagcg caagattgat cagaaagctg tggactcaca aattttacca aaaatcaaag    840

ctattcctca gctccagggc tacctgcgat ctgtgtttgc tctgacgaat ggaatttatc    900

ctcacaaatt ggtgttctaa atgtcttaag aacctaatta aatagctgac tacaaaaaaa    960

aaaaaaaaaa aa                                                        972


<210>  1008
<211>  866
<212>  DNA
<213>  Homo sapiens

<400>  1008
tcctcttttt ccggctggaa ccatggaggg tgtagaagag aagaagaagg aggttcctgc     60

tgtgccagaa acccttaaga aaaagcgaag gaatttcgca gagctgaaga tcaagcgcct    120

gagaaagaag tttgcccaaa agatgcttcg aaaggcaagg aggaagctta tctatgaaaa    180

agcaaagcac tatcacaagg aatataggca gatgtacaga actgaaattc gaatggcgag    240

gatggcaaga aaagctggca acttctatgt acctgcagaa cccaaattgg cgtttgtcat    300

cagaatcaga ggtatcaatg gagtgagccc aaaggttcga aaggtgttgc agcttcttcg    360

ccttcgtcaa atcttcaatg gaacctttgt gaagctcaac aaggcttcga ttaacatgct    420

gaggattgta gagccatata ttgcatgggg gtaccccaat ctgaagtcag taaatgaact    480

aatctacaag cgtggttatg gcaaaatcaa taagaagcga attgctttga cagataacgc    540

tttgattgct cgatctcttg gtaaatacgg catcatctgc atggaggatt tgattcatga    600

gatctatact gttggaaaac gcttcaaaga ggcaaataac ttcctgtggc ccttcaaatt    660

gtcttctcca cgaggtggaa tgaagaaaaa gaccacccat tttgtagaag gtggagatgc    720

tggcaacagg gaggaccaga tcaacaggct tattagaaga atgaactaag gtgtctacca    780

tgattatttt tctaagctgg ttggttaata aacagtacct gctctcaaat tgaaataaaa    840

aaaaaaaaaa aaaaaaaaaa aaaaaa                                         866


<210>  1009
<211>  890
<212>  DNA
<213>  Homo sapiens

<400>  1009
tttcctttct ctctcctccc gccgcccaag atgccgaaag gaaagaaggc caagggaaag     60

aaggtggctc cggccccagc tgtcgtgaag aagcaggagg ctaagaaagt ggtgaatccc    120

ctgtttgaga aaaggcctaa gaattttggc attggacagg acatccagcc caaaagagac    180

ctcacccgct ttgtgaaatg gccccgctat atcaggttgc agcggcagag agccatcctc    240

tataagcggc tgaaagtgcc tcctgcgatt aaccagttca cccaggccct ggaccgccaa    300

acagctactc agctgcttaa gctggcccac aagtacagac cagagacaaa gcaagagaag    360

aagcagagac tgttggcccg ggccgagaag aaggctgctg gcaaagggga cgtcccaacg    420

aagagaccac ctgtccttcg agcaggagtt aacaccgtca ccaccttggt ggagaacaag    480

aaagctcagc tggtggtgat tgcacacgac gtggatccca tcgagctggt tgtcttcttg    540

cctgccctgt gtcgtaaaat gggggtccct tactgcatta tcaagggaaa ggcaagactg    600

ggacgtctag tccacaggaa gacctgcacc actgtcgcct tcacacaggt gaactcggaa    660

gacaaaggcg ctttggctaa gctggtggaa gctatcagga ccaattacaa tgacagatac    720

gatgagatcc gccgtcactg gggtggcaat gtcctgggtc ctaagtctgt ggctcgtatc    780

gccaagctcg aaaaggcaaa ggctaaagaa cttgccacta aactgggtta aatgtacact    840

gttgagtttt ctgtacataa aaataattga aataatacaa attttccttc               890


<210>  1010
<211>  903
<212>  DNA
<213>  Homo sapiens

<400>  1010
agataaggcc gctcgctgac gccgtgtttc ctctttcggc cgcgctggtg aacaggaccc     60

gtcgccatgg gccgtgtgat ccgtggacag aggaagggcg ccgggtctgt gttccgcgcg    120

cacgtgaagc accgtaaagg cgctgcgcgc ctgcgcgccg tggatttcgc tgagcggcac    180

ggctacatca agggcatcgt caaggacatc atccacgacc cgggccgcgg cgcgcccctc    240

gccaaggtgg tcttccggga tccgtatcgg tttaagaagc ggacggagct gttcattgcc    300

gccgagggca ttcacacggg ccagtttgtg tattgcggca agaaggccca gctcaacatt    360

ggcaatgtgc tccctgtggg caccatgcct gagggtacaa tcgtgtgctg cctggaggag    420

aagcctggag accgtggcaa gctggcccgg gcatcaggga actatgccac cgttatctcc    480

cacaaccctg agaccaagaa gacccgtgtg aagctgccct ccggctccaa gaaggttatc    540

tcctcagcca acagagctgt ggttggtgtg gtggctggag gtggccgaat tgacaaaccc    600

atcttgaagg ctggccgggc gtaccacaaa tataaggcaa agaggaactg ctggccacga    660

gtacggggtg tggccatgaa tcctgtggag catccttttg gaggtggcaa ccaccagcac    720

atcggcaagc cctccaccat ccgcagagat gcccctgctg gccgcaaagt gggtctcatt    780

gctgcccgcc ggactggacg tctccgggga accaagactg tgcaggagaa agagaactag    840

tgctgagggc ctcaataaag tttgtgttta tgccaaaaaa aaaaaaaaaa aaaaaaaaaa    900

aaa                                                                  903


<210>  1011
<211>  962
<212>  DNA
<213>  Homo sapiens

<400>  1011
cttcttttcc gacaaaacac caaatggcgg atgacgccgg tgcagcgggg gggcccgggg     60

gccctggtgg ccctgggatg gggaaccgcg gtggcttccg cggaggtttc ggcagtggca    120

tccggggccg gggtcgcggc cgtggacggg gccggggccg aggccgcgga gctcgcggag    180

gcaaggccga ggataaggag tggatgcccg tcaccaagtt gggccgcttg gtcaaggaca    240

tgaagatcaa gtccctggag gagatctatc tcttctccct gcctattaag gaatcagaga    300

tcattgattt cttcctgggg gcctctctca aggatgaggt tttgaagatt atgccagtgc    360

agaagcagac ccgtgccggc cagcgcacca ggttcaaggc atttgttgct atcggggact    420

acaatggcca cgtcggtctg ggtgttaagt gctccaagga ggtggccacc gccatccgtg    480

gggccatcat cctggccaag ctctccatcg tccccgtgcg cagaggctac tgggggaaca    540

agatcggcaa gccccacact gtcccttgca aggtgacagg ccgctgcggc tctgtgctgg    600

tacgcctcat ccctgcaccc aggggcactg gcatcgtctc cgcacctgtg cctaagaagc    660

tgctcatgat ggctggtatc gatgactgct acacctcagc ccggggctgc actgccaccc    720

tgggcaactt cgccaaggcc acctttgatg ccatttctaa gacctacagc tacctgaccc    780

ccgacctctg gaaggagact gtattcacca agtctcccta tcaggagttc actgaccacc    840

tcgtcaagac ccacaccaga gtctccgtgc agcggactca ggctccagct gtggctacaa    900

catagggttt ttatacaaga aaaataaagt gaattaagcg tgaaaaaaaa aaaaaaaaaa    960

aa                                                                   962


<210>  1012
<211>  950
<212>  DNA
<213>  Homo sapiens

<400>  1012
tagacggcgc gccccgcccc cgtacgccta agttctcgcg cgactcccac ttccgccctt     60

ttggctctct gaccagcacc atggcggttg gcaagaacaa gcgccttacg aaaggcggca    120

aaaagggagc caagaagaaa gtggttgatc cattttctaa gaaagattgg tatgatgtga    180

aagcacctgc tatgttcaat ataagaaata ttggaaagac gctcgtcacc aggacccaag    240

gaaccaaaat tgcatctgat ggtctcaagg gtcgtgtgtt tgaagtgagt cttgctgatt    300

tgcagaatga tgaagttgca tttagaaaat tcaagctgat tactgaagat gttcagggta    360

aaaactgcct gactaacttc catggcatgg atcttacccg tgacaaaatg tgttccatgg    420

tcaaaaaatg gcagacaatg attgaagctc acgttgatgt caagactacc gatggttact    480

tgcttcgtct gttctgtgtt ggttttacta aaaaacgcaa caatcagata cggaagacct    540

cttatgctca gcaccaacag gtccgccaaa tccggaagaa gatgatggaa atcatgaccc    600

gagaggtgca gacaaatgac ttgaaagaag tggtcaataa attgattcca gacagcattg    660

gaaaagacat agaaaaggct tgccaatcta tttatcctct ccatgatgtc ttcgttagaa    720

aagtaaaaat gctgaagaag cccaagtttg aattgggaaa gctcatggag cttcatggtg    780

aaggcagtag ttctggaaaa gccactgggg acgagacagg tgctaaagtt gaacgagctg    840

atggatatga accaccagtc caagaatctg tttaaagttc agacttcaaa tagtggcaaa    900

taaaaagtgc tatttgtgat ggtttgcttc tgaaaaaaaa aaaaaaaaaa               950


<210>  1013
<211>  5793
<212>  DNA
<213>  Homo sapiens

<400>  1013
gctgctgctg cagtgggaca ggtggcggcg accggcggcg tccgaggaga tttaatccag     60

agactgactt cactatagaa cccacagttg tatcaatggt tggggaaaga tagtggcaac    120

aggcaaagga gaaacagctc tgacatacaa agaaaatgag tatgctaaag ccaagtgggc    180

ttaaggcccc caccaagatc ctgaagcctg gaagcacagc tctgaagaca cctacggctg    240

ttgtagctcc agtagaaaaa accatatcca gtgaaaaagc atcaagcact ccatcatctg    300

agactcagga ggaatttgtg gatgactttc gagttgggga gcgagtttgg gtgaatggaa    360

ataagcctgg atttatccag tttcttggag aaacccagtt tgcaccaggc cagtgggctg    420

gaattgtttt agatgaaccc ataggcaaga acgatggttc ggtggcagga gttcggtatt    480

tccagtgtga acctttaaag ggcatattta cccgaccttc aaagttaaca aggaaggtgc    540

aagcagaaga tgaagctaat ggcctgcaga caacgcccgc ctcccgagct acttcaccgc    600

tgtgcacttc tacggccagc atggtgtctt cctccccctc caccccttca aacatccctc    660

agaaaccatc acagccagca gcaaaggaac cttcagctac gcctccgatc agcaacctta    720

caaaaactgc cagtgaatct atctccaacc tttcagaggc tggctcaatc aagaaaggag    780

aaagagagct caaaatcgga gacagagtat tggttggtgg cactaaggct ggtgtagtcc    840

ggtttcttgg ggagaccgac tttgccaagg gggagtggtg tggcgtggag ttagatgagc    900

cacttgggaa gaatgatggc gctgttgctg gaacaaggta ttttcagtgt caacccaaat    960

atggcttgtt cgctcctgtc cacaaagtta ccaagattgg cttcccttcc actacaccag   1020

ccaaagccaa ggccaacgca gtgaggcgag tgatggcgac cacgtccgcc agcctgaagc   1080

gcagcccttc tgcctcttcc ctcagctcca tgagctcagt ggcctcctct gtgagcagca   1140

ggcccagtcg gacaggacta ttgactgaaa cctcctcccg ttacgccagg aagatctccg   1200

gtaccactgc cctccaggag gccctgaagg agaagcagca gcacattgag cagctgctgg   1260

cggaacggga tctggagagg gcggaggtgg ccaaggccac gagccacgtg ggggagatag   1320

agcaggagct agctctggcc cgggacggac atgaccagca tgtcctggaa ttggaagcca   1380

aaatggacca gctgcgaaca atggtggaag ctgctgacag ggagaaggtg gagcttctca   1440

accagcttga agaggagaaa aggaaggttg aggaccttca gttccgggtt gaagaagaat   1500

caattaccaa aggtgatctt gaggtggcta cagtttcaga aaagtcacgt ataatggaac   1560

tggagaaaga cctagcattg agagtacagg aagtagctga gctccgaaga aggctagagt   1620

ccaataagcc tgctggggat gtggacatgt cactttccct tttgcaagag ataagctctt   1680

tgcaagaaaa gttagaagtc acccgtactg accaccagag agaaataact tctctgaagg   1740

agcattttgg agcccgggaa gaaactcatc agaaggagat aaaggctctg tataccgcca   1800

cggaaaagct ttccaaagag aacgagtcat tgaaaagcaa gctggagcat gccaacaaag   1860

agaactcaga tgtgatagct ctatggaagt ccaaactgga gactgccatc gcatcccacc   1920

agcaggcgat ggaagaactg aaggtatctt tcagcaaagg gcttggaaca gagacggcag   1980

aatttgctga actaaaaaca caaatagaga aaatgagact agattaccaa cacgaaatag   2040

aaaatttgca gaatcaacaa gactctgaac gggctgccca tgctaaagag atggaagcct   2100

tgagggctaa actgatgaaa gttattaaag aaaaggaaaa cagtctggaa gccatcaggt   2160

cgaaactgga caaagcagaa gaccagcatc tcgtagaaat ggaagacacg ttaaacaaat   2220

tacaggaagc tgaaataaag gtaaaggagc tagaggtact gcaagccaaa tgcaatgaac   2280

aaaccaaggt tattgataat tttacatcac agctcaaggc tactgaagaa aagctcttgg   2340

atcttgatgc acttcggaaa gccagttccg aaggtaaatc ggaaatgaag aaacttagac   2400

agcagcttga ggcagctgag aaacagatta aacatttaga gattgaaaag aatgctgaaa   2460

gtagcaaggc tagtagcatt accagagagc tccaggggag agagctaaag cttactaacc   2520

ttcaggaaaa tttgagtgaa gtcagtcaag tgaaagagac tttggaaaaa gaacttcaga   2580

ttttgaaaga aaagtttgct gaagcttcag aggaggcagt ctctgttcag agaagtatgc   2640

aagaaactgt aaataagtta caccaaaagg aggaacagtt taacatgctg tcttctgact   2700

tggagaagct gagagaaaac ttagcagata tggaggcaaa atttagagag aaagatgaga   2760

gagaagagca gctgataaag gcaaaggaaa aactggaaaa tgacattgca gaaataatga   2820

agatgtcagg agataactct tctcagctga caaaaatgaa cgatgaatta cgtctgaaag   2880

aaagagatgt agaagaatta cagctaaaac ttacaaaggc taatgaaaat gcaagttttc   2940

tgcaaaaaag tattgaggac atgactgtca aagctgaaca gagccagcaa gaagcagcta   3000

aaaagcatga ggaagaaaag aaagaattgg agaggaaatt gtcggacctg gaaaagaaaa   3060

tggaaacaag ccacaaccag tgtcaggagc tgaaagccag gtatgagaga gccacttctg   3120

agacaaaaac caagcatgaa gaaatcctac agaacctcca gaagacgctg ctggacacag   3180

aggacaagct gaagggcgca cgggaggaga acagtggctt gctgcaggag ctggaggagc   3240

tgagaaagca agccgacaaa gccaaagctg ctcaaacagc ggaagatgcc atgcagataa   3300

tggaacagat gaccaaagag aagactgaga ctctggcctc cttggaggac accaagcaaa   3360

caaatgcaaa actacagaat gaattggaca cacttaaaga aaacaacttg aaaaatgtgg   3420

aagagctgaa caaatcaaaa gaactcctga ctgtagagaa tcaaaaaatg gaagaattta   3480

ggaaagaaat agaaacccta aagcaggcag cagctcagaa gtcccagcag ctttcagcgt   3540

tgcaagaaga gaacgttaaa cttgctgagg agctggggag aagcagggac gaagtcacaa   3600

gtcatcaaaa gctggaagaa gaaagatctg tgctcaataa tcagttgtta gaaatgaaaa   3660

aaagagaatc caagttcata aaagacgcag atgaagagaa agcttccttg cagaaatcca   3720

tcagtataac tagtgcctta ctcacagaaa aggatgccga gctggagaaa ctgagaaatg   3780

aggtcacagt gctcagggga gaaaacgcct ctgccaagtc cttgcattca gttgttcaga   3840

ctctagagtc tgataaggtg aagctcgagc tcaaggtaaa gaacttggag cttcaactca   3900

aagaaaacaa gaggcagctc agcagctcct caggtaatac agacactcag gcagacgagg   3960

atgaaagagc ccaggagagt cagattgatt tcctaaattc agtaatagtg gaccttcaaa   4020

ggaagaatca agacctcaag atgaaggtgg agatgatgtc agaagcagcc ctgaatggga   4080

acggggatga cctaaacaat tatgacagtg atgatcagga gaaacagtcc aagaagaaac   4140

ctcgcctctt ctgtgacatt tgtgactgct ttgatctcca cgacacagag gattgtccta   4200

cccaggcaca gatgtcagag gaccctcccc attccacaca ccatggcagt cggggtgagg   4260

aacgcccata ctgtgaaatc tgtgagatgt ttggacactg ggccaccaac tgcaatgacg   4320

acgaaacctt ctgatgaagc ctccagtgga gaactgggct tgctcagacg cactcgcatt   4380

gacacaacgt aacaccagca ttgtgtgtgc agacttcagg agaactcatg ttatttttta   4440

accccgtcaa caaatctagg aaaatatttt gatcttcaac aaattgccct ttagtctccc   4500

cgtatgagtt agaataataa atatttagta ggtgagtttt cacctcgaat tttgttttct   4560

tgatttttac gtttgaagac attgcaccag atgccattac atttattggc cccccgacct   4620

tgtagaaaaa cccctaccct cacaatacct tatttaagta actttaaatt atgccgttac   4680

ttttcatatt tgcactaaga tatttccagg ctgcatttgt atatttagat tttttggtta   4740

agctttgaca ctggaatgag ttgaaaaaat gtgccatttt gcattttcat ctactcattt   4800

aaagtatttt attcttattc aaagaaatat ctgagctctt tgcactacct gttatcagta   4860

gtgcctttac ttcaggcttg ataatactta ggtgtgatta taaaatcatg aagcaggtaa   4920

agggaggggc aagcccccaa actgctgtgg ggacatttta taatctatat gctgcaccca   4980

cttaatctac tgtggtgttt tgtttattag ttttgcataa tttcagcttc tatatattgt   5040

atgtatatat tttttaaaaa tctatatttt gggaaaaaaa catacacaat gtgtctttct   5100

ttttggacat ttaccttttt gaaaaagaaa acacttaaaa tgatcattag gacataacag   5160

actaggccag acatagcatc ttgtggcttt gcaaccattt tcatttgttt gttttccttt   5220

tatttcttca ccagatttaa ataactggag gaattttctc caattttttt ttccttctct   5280

ggcaggtatc cccagcagtc aattaacaat aagccagtat aaaacaccta aataaccaat   5340

ctacaatctc ccttcacaag tttttttact gtttttagat gaatgtacga tgagaaattc   5400

aacgttaata attctggatt ttcttatcac aaaaaagaaa atgaaggacc tcaaagcacc   5460

tgaacagttt atcgaccagt ttgaatctat ttatcttcat ttgaatgtct tctagaatat   5520

gtaaaaagtc ataaaatgta tcttccatgc tacatgtaca ataagaactt ctataattgt   5580

atatatgcct ttgatgtatt ttcccctcaa gattatcaac tgtgtgttcg acagtgaata   5640

ttcaatctgg taccagttga aatttttggt tataaatgta atacgaattg tttcacaaac   5700

agaaaacatg taaagcagta ttaaaatttg gccaaacaag tgttctgtat ctactttaat   5760

aaatggttat tctttaaaaa aaaaaaaaaa aaa                                5793


<210>  1014
<211>  6039
<212>  DNA
<213>  Homo sapiens

<400>  1014
tctcgcaggc agggctgggc cgggcaggag ctgcgaggcc ggcacaaggg aggcggccct     60

ggggacctga cagggcgggg gcgggggcgg gcacgccgcc gcctgcgcgg ttccgggtgc    120

tcccggcgcg gcgctgccca gggcacactt gaccgaggtc gggctgcggg gaaaggcggg    180

tctggggaga accccgagag acgcggcgtc ctccaactcc tcctccttct cctcgcggcc    240

gccgaagcca cagcccgagc ccgagcccga gcccgagccg gcgccaccgc gcccccggcc    300

atggcttttg ccaatttccg ccgcatcctg cgcctgtcta ccttcgagaa gagaaagtcc    360

cgcgaatatg agcacgtccg ccgcgacctg gaccccaacg aggtgtggga gatcgtgggc    420

gagctgggcg acggcgcctt cggcaaggtt tacaaggcca agaataagga gacgggtgct    480

ttggctgcgg ccaaagtcat tgaaaccaag agtgaggagg agctggagga ctacatcgtg    540

gagattgaga tcctggccac ctgcgaccac ccctacattg tgaagctcct gggagcctac    600

tatcacgacg ggaagctgtg gatcatgatt gagttctgtc cagggggagc cgtggacgcc    660

atcatgctgg agctggacag aggcctcacg gagccccaga tacaggtggt ttgccgccag    720

atgctagaag ccctcaactt cctgcacagc aagaggatca tccaccgaga tctgaaagct    780

ggcaacgtgc tgatgaccct cgagggagac atcaggctgg ctgactttgg tgtgtctgcc    840

aagaatctga agactctaca gaaacgagat tccttcatcg gcacgcctta ctggatggcc    900

cccgaggtgg tcatgtgtga gaccatgaaa gacacgccct acgactacaa agccgacatc    960

tggtccctgg gcatcacgct gattgagatg gcccagatcg agccgccaca ccacgagctc   1020

aaccccatgc gggtcctgct aaagatcgcc aagtcggacc ctcccacgct gctcacgccc   1080

tctaagtggt ctgtagagtt ccgtgacttc ctgaagatag ccctggataa gaacccagaa   1140

acccgaccca gtgccgcgca gctgctggag catcccttcg tcagcagcat caccagtaac   1200

aaggctctgc gggagctggt ggctgaggcc aaggccgagg tgatggaaga gatcgaagac   1260

ggccgggatg agggggaaga ggaggacgcc gtggatgccg cctccaccct ggagaaccat   1320

actcagaact cctctgaggt gagtccgcca agcctcaatg ctgacaagcc tctcgaggag   1380

tcaccttcca ccccgctggc acccagccag tctcaggaca gtgtgaatga gccctgcagc   1440

cagccctctg gggacagatc cctccaaacc accagtcccc cagtcgtggc ccctggaaat   1500

gagaacggcc tggcagtgcc tgtgcccctg cggaagtccc gacccgtgtc aatggatgcc   1560

agaattcagg tagcccagga gaagcaagtt gctgagcagg gtggggacct cagcccagca   1620

gccaacagat ctcaaaaggc cagccagagc cggcccaaca gcagcgccct ggagaccttg   1680

ggtggggaga agctggccaa tggcagcctg gagccacctg cccaggcagc tccagggcct   1740

tccaagaggg actcggactg cagcagcctc tgcacctctg agagcatgga ctatggtacc   1800

aatctctcca ctgacctgtc gctgaacaaa gagatgggct ctctgtccat caaggacccg   1860

aaactgtaca aaaaaaccct caagcggaca cgcaaatttg tggtggatgg tgtggaggtg   1920

agcatcacca cctccaagat catcagcgaa gatgagaaga aggatgagga gatgagattt   1980

ctcaggcgcc aggaactccg agagcttcgg ctgctccaga aagaagagca tcggaaccag   2040

acccagctga gtaacaagca tgagctgcag ctggagcaaa tgcataaacg ttttgaacag   2100

gaaatcaacg ccaagaagaa gttctttgac acggaattag agaacctgga gcgtcagcaa   2160

aagcagcaag tggagaagat ggagcaagac catgccgtgc gccgccggga ggaggccagg   2220

cggatccgcc tggagcagga tcgggactac accaggttcc aagagcagct caaactgatg   2280

aagaaagagg tgaagaacga ggtggagaag ctcccccgac agcagcggaa ggaaagcatg   2340

aagcagaaga tggaggagca cacgcagaaa aagcagcttc ttgaccggga ctttgtagcc   2400

aagcagaagg aggacctgga gctggccatg aagaggctca ccaccgacaa caggcgggag   2460

atctgtgaca aggagcgcga gtgcctcatg aagaagcagg agctccttcg agaccgggaa   2520

gcagccctgt gggagatgga agagcaccag ctgcaggaga ggcaccagct ggtgaagcag   2580

cagctcaaag accagtactt cctccagcgg cacgagctgc tgcgcaagca tgagaaggag   2640

cgggagcaga tgcagcgcta caaccagcgc atgatagagc agctgaaggt gcggcagcaa   2700

caggaaaagg cgcggctgcc caagatccag aggagtgagg gcaagacgcg catggccatg   2760

tacaagaaga gcctccacat caacggcggg ggcagcgcag ctgagcagcg tgagaagatc   2820

aagcagttct cccagcagga ggagaagagg cagaagtcgg agcggctgca gcaacagcag   2880

aaacacgaga accagatgcg ggacatgctg gcgcagtgtg agagcaacat gagcgagctg   2940

cagcagctgc agaatgaaaa gtgccacctc ctggtagagc acgaaaccca gaaactgaag   3000

gccctggatg agagccataa ccagaacctg aaggaatggc gggacaagct tcggccgcgc   3060

aagaaggctc tggaagagga tctgaaccag aagaagcggg agcaggagat gttcttcaag   3120

ctgagcgagg aggcggagtg cccaaacccc tccaccccaa gcaaggccgc caagttcttc   3180

ccctacagtt ctgcggatgc ttcttaacaa ccgcccgggg ctgtggctgg cagcttggtg   3240

ggccccaggg ccttctcctt cattctctgt gaacatgtaa ctcaggaccc cttttccctc   3300

ttgcgtctgt gccagctcaa atccagcccc tcgccctgtg ccaccccaac tgtgcctgat   3360

agacctgccc cagcgttcct gacttcttgc tggcctgtgg agggtgaggt gtaattattt   3420

gtcacctgaa cctaatgtat attctccttg agccccagat cccttcaagc tggaagggat   3480

ggggctgttg gtggggtcag ggtccaagag gaatgggtgt tctgtggcct cgagtcctct   3540

cctgtttgcg aaaataccag ttttgctctc tgtgggacaa agcactgctg atgaagtccc   3600

cgtgggctca tccgggctgg aattcttggt ttttcagcca ttccctgcag agtcactcaa   3660

tcatcaagtc cctcacagcc atttctgttc ccagaggagc caggcctgca gctggctgct   3720

caggagatgg cctcattcct cctgttctcc cagtttgctt tccacttaag acaaagcctt   3780

gtctatgtgg ggggcgggga ccggggaaag agggaggctg aaatgtttat tctgcttctc   3840

ccgtgtttca tgccatctcg cgtccccctt cctgcacatg ggtgtgaatg cacacacata   3900

cgcgtacaca caggacttgg tctgctggcc tggcctcttc tgcccaggtg ggttggaaca   3960

cgtttgctgc ctgagcctgt gccactgagc atgttaggtg gagcagttgg tgtggcacgt   4020

gcggggtgtt ggcaccggag gcatggaaaa gcacaggctg tactgccagg ctgcgatgcg   4080

tgctggcccc cgcacaggct cctgtgtgca gggactgatt cctcagcaca cgaggcttcc   4140

acaacccagt ctgctccata gcactctggc ccaccctgtc tgcaggtgaa acaggagggc   4200

tgtttgcctc tgccccatcc ccccgactgt gttcaggagt cccaccttgc atttcagacc   4260

tgggctggca gtctgttgga cttctcttca ggaagaaaaa gcatcagggg gaaatggaat   4320

gcccctgccc caggaacatg gcagaagcac aggttctgta cctcagatgg actcctgctg   4380

ggccttcggg gtctcagttg gcttccccca gattctgatt ctacagctgc agaatgtata   4440

taacgcaata aaagcaaatg tttgaaccag tatgcgggtt tacttacaag gaaacctttt   4500

ttcaccctga tttctaatta ttttattgaa acaactataa aatgtatggt ttctccagga   4560

agatatctgc tttttaaaac aacaaacaag aacaacaaca caaaactggt aatgatttgg   4620

agtaatcatg cgggcatatt gagtctgggt agtgtttcgc tggtggtaga gtggttgaga   4680

cttcctggga ggactttttc cgccttcact cctacagatt taagattctt tatttttagg   4740

ccgggcatgg tgactcacct gaggtgagga gttcgagact agcctggcca acatggcaaa   4800

accctgtctc tactaaaagt acaaaaatta gccaggcgtg gtggtgcatg cctataatcc   4860

cagctactcg ggaggctgag gcaggagaat cgcttgaacc caggaggcag aggttgcagt   4920

aagccaaggt cacaccactg cactccagcc taggtgacag ggcgagactc tgtctctcaa   4980

aaaaaaaaaa aaaaaaaatt ctttgagaca gggtctctaa tatgttgccc aagctgatct   5040

caaactcgtg gctcaactga ttctcccgct tcaaccttga gtagctggga cgacagatac   5100

atgctactgc acccagctag gttaaggttc tgtatactct gtctttctaa agcaattccc   5160

tggaaatttt ctcaacattg gttataactg aatgcttggg aagggagggg cagcccttca   5220

acaggaaaag gggactgccc aaatcttaaa tgcacagtca agattctctt ggagctagca   5280

atggttctca ggttagtgag catttagctt gcctgctgca gaatttgacc cagatggggg   5340

tgttttttag gtctctcaca aatgagacaa gcgaaacaat tgtctccttt tattctcttt   5400

ggtgcattgg tgctggggaa acatgaacta gcggcagtgt aactgcagaa catagaccca   5460

gttctaccag gccaggccag cgttgggaac caccagacag ggctgctttg ggctttgctt   5520

acagtatttc catgtgtagc ctggcgtgtg agaaagtatt aggtgaaatg ccagtttcat   5580

ggttcaggtg aaagtctgtg atcattcccc tcgtggctcg tccttcacat cacttttgcc   5640

cttcaaggag ttgccgcgtc cccgctcagt gccgcctgag ccctcagagc tcccctgtgc   5700

ttttctggat ggggactggc ggggtcacct agcctcaccg tggagccacc gtgcaatgcc   5760

catctctgag aggcccacgc ggtattcctc gtgccctgtg ttagtgcttt ctgtataagg   5820

gacagacaga actgggtttt tttcctctgt ctggttttag agtaaatgta actaactttt   5880

attttccctt tatgaaagat agaaattatt tttatgtagt ttccagactt tatacaaaat   5940

ttttgtaaaa tgttctctgg aaagttaact acaagaatgt aaatatgctt ctaataaaat   6000

aacaaggtta tttgccgtta aaaaaaaaaa aaaaaaaaa                          6039


<210>  1015
<211>  1173
<212>  DNA
<213>  Homo sapiens

<400>  1015
aagccgtcgc ggcggggacc atgttgcttc cgaacatcct gctcaccggt acaccagggg     60

ttggaaaaac cacactaggc aaagaacttg cgtcaaaatc aggactgaaa tacattaatg    120

tgggtgattt agctcgagaa gtctgatcat cggatatcat ggagtctggc aagacggctt    180

ctcccaagag catgccgaaa gatgcacaga tgatggcaca aatcctgaag gatatgggga    240

ttacagaata tgagccaaga gttataaatc agatgttgga gtttgccttc cgatatgtga    300

ccacaattct agatgatgca aaaatttatt caagccatgc taagaaagct actgttgatg    360

cagatgatgt gcgattggca atccagtgcc gcgctgatca gtcttttacc tctcctcccc    420

caagagattt tttattagat attgcaaggc aaagaaatca aacccctttg ccattgatca    480

agccatattc aggtcctagg ttgccacctg atagatactg cttaacagct ccaaactata    540

ggctgaaatc tttacagaaa aaggcatcaa cttctgcggg aagaataaca gtcccgcggt    600

taagtgttgg ttcagttact agcagaccaa gtactcccac actaggcaca ccaaccccac    660

agaccatgtc tgtttcaact aaagtaggga ctcccatgtc cctcacaggt caaaggttta    720

cagtacagat gcctacttct cagtctccag ctgtaaaagc ttcaattcct gcaacctcag    780

cagttcagaa tgttctgatt aatccatcat taatcgggtc caaaaacatt tttattacca    840

ctaatatgat gtcatcacaa aatactgcca atgaatcatc aaatgcattg aaaagaaaac    900

gtgaagatga tgatgatgac gatgatgatg atgatgacta tgataatctg taatctagcc    960

ttgctgaatg taacatgtat acttggtctt gaattcattg tactgatatt aaacatgcat   1020

gctggatgtt ttcaagttgt gttttagaaa actaataata atgagtaaac acagttacca   1080

tacttttcaa ttgaaatgaa ggtttttcat cagccttaaa agtgtaagaa aaataaagtt   1140

gtcattcatt cgaaaaaaaa aaaaaaaaaa aaa                                1173


<210>  1016
<211>  1052
<212>  DNA
<213>  Homo sapiens

<400>  1016
acctgcgggc gcagtggacc cgaccgctcc gctcgtccgc tccctccccc gcgccgtgca     60

cgtcttggtt cgggccgggc ataaaaggct tcgcggccca gggctcactt ggcgctgaga    120

acgcgggtcc acgcgtgtga tcgtccgtgc gtctagcctt tgcccacgca gctttcagtc    180

atggcctccg gtaacgcgcg catcggaaag ccagcccctg acttcaaggc cacagcggtg    240

gttgatggcg ccttcaaaga ggtgaagctg tcggactaca aagggaagta cgtggtcctc    300

tttttctacc ctctggactt cacttttgtg tgccccaccg agatcatcgc gttcagcaac    360

cgtgcagagg acttccgcaa gctgggctgt gaagtgctgg gcgtctcggt ggactctcag    420

ttcacccacc tggcttggat caacaccccc cggaaagagg gaggcttggg ccccctgaac    480

atccccctgc ttgctgacgt gaccagacgc ttgtctgagg attacggcgt gctgaaaaca    540

gatgagggca ttgcctacag gggcctcttt atcatcgatg gcaagggtgt ccttcgccag    600

atcactgtta atgatttgcc tgtgggacgc tccgtggatg aggctctgcg gctggtccag    660

gccttccagt acacagacga gcatggggaa gtttgtcccg ctggctggaa gcctggcagt    720

gacacgatta agcccaacgt ggatgacagc aaggaatatt tctccaaaca caattaggct    780

ggctaacgga tagtgagctt gtgcccctgc ctaggtgcct gtgctgggtg tccacctgtg    840

cccccacctg ggtgccctat gctgacccag gaaaggccag acctgcccct ccaaactcca    900

cagtatggga ccctggaggg ctaggccaag gccttctcat gcctccacct agaagctgaa    960

tagtgacgcc ctcccccaag cccacccagc cgcacacagg cctagaggta accaataaag   1020

tattagggaa aggtgtgaaa aaaaaaaaaa aa                                 1052


<210>  1017
<211>  4182
<212>  DNA
<213>  Homo sapiens

<400>  1017
agacgcagag tagattgtga ttggctcggg ctgcggaacc tcggaaaccc gaatgtgagg     60

accttaaggg atccacagct gccgcccccc gcagccatcc agagcgcggt cacagtccga    120

ctggcggcac ggaggcggcg gcggcggcgg cggcggcagc ggcggcggca gcggcggcgg    180

cagctgtagc tgcagcagca ggtaaagaga gcgttttccc aaagaaaata acatagcaca    240

gaaggaaaaa taaaaagaaa ttgctgcaga ttttacttta tgtgagaaaa tctacaattt    300

cttcgagaca ctcatataaa gatattggtg aatgaacttt gctaagtatg gattcaggcg    360

gtggaagtct tggattgcac acgccagact ctagaatggc ccataccatg attatgcaag    420

attttgtggc tggaatggct ggtactgcac atatcgatgg agaccatatt gttgtttcag    480

ttcctgaagc tgttttagtt tctgatgttg tcacagatga tgggataact cttgatcatg    540

gccttgcagc tgaagttgtc catggacctg atatcatcac agagactgat gtagtaacag    600

aaggtgtgat tgttcctgaa gcggtacttg aagctgatgt tgccattgaa gaggatttag    660

aggaagatga tggtgatcac atcttgactt ctgaactaat tacagaaacc gttagggtac    720

cagagcaggt tttcgtggct gaccttgtta ctggtcctaa tggacactta gaacatgtgg    780

tccaagattg tgtttcagga gtcgactctc ccacaatggt atcagaggag gttcttgtaa    840

ctaattcaga tacagaaact gtgattcaag cagctggagg tgttcctggt tctacagtta    900

ctataaaaac cgaagatgat gatgatgatg atgtcaagag cacttctgaa gactacttaa    960

tgatatcttt ggatgatgtt ggagaaaaat tagagcatat ggggaataca ccattaaaaa   1020

ttggcagtga tggttcacaa gaagatgcta aagaagatgg gtttggttct gaagttataa   1080

aagtgtatat atttaaagcg gaggctgaag atgatgttga aataggtgga acagaaattg   1140

tcacagagag tgagtacacc agtggacatt cagtagctgg agtgcttgac cagagccgaa   1200

tgcagcggga gaagatggtt tacatggcag ttaaagattc ttctcaagaa gaagatgata   1260

tcagagatga aagaagagtt tcccgaaggt atgaagattg tcaagcatca ggaaatactt   1320

tggactcagc attagaaagc agaagtagta cagcagcaca gtaccttcaa atttgtgacg   1380

gcattaatac aaataaagta cttaaacaaa aagccaaaaa gaggagaagg ggagaaacca   1440

ggcagtggca aacagctgtt ataataggtc ctgatggaca gcccctcaca gtgtaccctt   1500

gccatatttg cacaaaaaag tttaaatcca ggggattctt aaaaagacac atgaagaatc   1560

atcctgatca tttaatgaga aaaaaatatc agtgtacaga ttgtgacttt acaactaaca   1620

agaaagtgag tttccataac cacttagaaa gccataagct cataaacaaa gtcgacaaaa   1680

cccatgaatt tacagaatac acacgaagat acagagaggc tagtccactg agttccaata   1740

aacttatttt aagagacaag gagccgaaga tgcacaagtg caaatactgt gactatgaaa   1800

ctgcagaaca aggactgtta aacaggcatt tgttggccgt tcacagcaag aattttcctc   1860

atgtttgtgt tgagtgtggg aagggttttc gacatccttc tgaactcaag aaacatatga   1920

gaacccatac tggtgagaag ccatatcagt gtcagtattg tattttcagg tgtgcagatc   1980

aatcaaatct gaaaactcac attaagtcta aacatggtaa caatttgcca tataaatgtg   2040

agcattgtcc ccaagcattt ggtgatgaga gggagcttca acgccatctg gatttgtttc   2100

aaggacataa gacacaccag tgtcctcatt gtgaccataa gagcaccaat tcaagtgacc   2160

ttaagcggca catcatatct gtccatacta aggattttcc tcacaaatgt gaggtctgtg   2220

ataaaggttt tcatcgtcct tctgagctca aaaagcatag tgatatccat aagggtagga   2280

agattcatca gtgcaggcac tgtgacttta aaacatccga tccatttatt cttagtggcc   2340

atatcctttc agttcatact aaagatcagc cattgaaatg taaaaggtgc aagagaggat   2400

tcagacaaca aaatgagcta aaaaaacata tgaagaccca tactggaagg aagatttacc   2460

aatgtgagta ttgtgaatac agcactacag atgcatctgg ctttaaacga catgtgatat   2520

caatacatac aaaagactat ccacacaggt gtgaattctg caagaaggga ttccgaagac   2580

catcagaaaa aaatcagcat attatgaggc accacaaaga ggctcttatg taataagatc   2640

aatataaaga aagaagctat ttaggagata tgatatgcta cttgggagaa aactctcact   2700

aactgtctca ccgggtttca aagcttgata ctaaaccatg actttacatt ctttgtatta   2760

aagatcttaa aatatttgaa ttcacagggg atcccatagc cctttgaaaa ttacttaaag   2820

aatttaagaa gcactataga atggttacag aaaaacttct taagtatctg tgtaatagta   2880

ttatatgcat acttaaacta cagaggggaa aagcaaagac aaatacttta tttggctgat   2940

tatgttagat acaaatgttt ctgagaagag aatacataat tgagtttagt gatgctttgc   3000

tatagcaagc aaacccactt ttatgcaatt ttagaaatgg ggcagggaaa caaaatgtgg   3060

tcattcatca gtcacttagt cattgagcct tttatattgt acctggaaat taaattccag   3120

caatgacaaa agttttgtgt attcattaaa agaaaactaa ctggaaaaca ggttagatta   3180

attcagtact attaaaaaag aattcagagc tgttaatatt ttatcacagg ataggatact   3240

taaaatatag cattctgtgc tgagatctaa ggtgaagtct ataaagatta aagttccctt   3300

ttttctgatg ttcaagttga ttgttgttca gtatggcata tatgacaaaa gtatatttga   3360

gtcaaatgtg gctttctaaa atggatgcaa cattagcgtt gcaaacaaaa tcagcactat   3420

atttcttaat gatctaaaga ttaatttgag agaacacagt tttcttaaat attataatgt   3480

ctagagtttt tttaggacag tcttagcaag tatgattgtt ctagtcttac ttgctctaat   3540

gtttaaaggt gcaattttat gccattattg aaattgattt ttaaaatcta tataccatat   3600

gattaacatg cattttcaat atgaggcagt gtttatgcag tatttaacag agcaatctgc   3660

tgccaataga gtttggaggt ggatatttag tttacagtgt ataaacttaa aatatgcatc   3720

cctttaacaa cgctttgtgt tagcatgctg caaatcaaaa tggcacttaa tattaaaagc   3780

tggtttaggg aaattttatg aaaatcctgt tcataaatgt aatgcatatg atatgtactt   3840

ttaagtttta gttgcttcat gtttacattc agctgttcaa cataattaaa atgtaatttt   3900

acttcatgct atattgtggc tttgtgtttc aaataatgtt cacctttctg tttttgcacc   3960

agataagaat cagttccttg agaataaatt ttttatcttt cttaacttca gaatattaaa   4020

tttggaatat ctactaaaat tgtgtgttat gtggctgtaa atgatgtaca cgctgtaaaa   4080

taagatcgct actgttatgt gggattatta tttctaaatg ttactcattg aaatgagcat   4140

acaataaaaa gcatttattg cacttaaaaa aaaaaaaaaa aa                      4182


<210>  1018
<211>  916
<212>  DNA
<213>  Homo sapiens

<400>  1018
agcgagccca gctccggtcc cagccccggc cgtcccggcg tcgcttcgga gcgcggcggc     60

agctgactgc gccttcacga tccgctggga cccgcgagcc ccgccgccgt tatgaacatc    120

cgcaatgcga ggccagagga cctaatgaac atgcagcact gcaacctcct ctgcctgccc    180

gagaactacc agatgaaata ctacttctac catggccttt cctggcccca gctctcttac    240

attgctgagg acgagaatgg gaagattgtg gggtatgtcc tggccaaaat ggaagaggac    300

ccagatgatg tgccccatgg acatatcacc tcattggctg tgaagcgttc ccaccggcgc    360

ctcggtctgg ctcagaaact gatggaccag gcctctcgag ccatgataga gaacttcaat    420

gccaaatatg tctccctgca tgtcaggaag agtaaccggg ccgccctgca cctctattcc    480

aacaccctca actttcagat cagtgaagtg gagcccaaat actatgcaga tggggaggac    540

gcctatgcca tgaagcggga cctcactcag atggccgacg agctgaggcg gcacctggag    600

ctgaaagaga agggcaggca cgtggtgctg ggtgccatcg agaacaaggt ggagagcaaa    660

ggcaattcac ctccgagctc aggagaggcc tgtcgcgagg agaagggcct ggctgccgag    720

gatagtggtg gggacagcaa ggacctcagc gaggtcagcg agaccacaga gagcacagat    780

gtcaaggaca gctcagaggc ctccgactca gcctcctaga gcctgcccca tcccctcctc    840

accccacgag ctttcacaat aaatttgctc cgtggcactg ggaaaaaaaa aaaaaaaaaa    900

aaaaaaaaaa aaaaaa                                                    916


<210>  1019
<211>  2379
<212>  DNA
<213>  Homo sapiens

<400>  1019
ctcttggaga cggcgaccca ggcatctggg gagccacaga agtcgtactc ccttaaaccc     60

tgctttgctc cccctgtgga tgtaacccct tagctggcat tttgcatctc aattggcttg    120

tgatggaggc gtctttgggg attcagatgg atgagccaat ggctttttct ccccagcgtg    180

accggtttca ggctgaaggc tctttaaaaa aaaacgagca gaattttaaa cttgcaggtg    240

ttaaaaaaga tattgagaag ctttatgaag ctgtaccaca gcttagtaat gtgtttaaga    300

ttgaggacaa aattggagaa ggcactttca gctctgttta tttggccaca gcacagttac    360

aagtaggacc tgaagagaaa attgctctaa aacacttgat tccaacaagt catcctataa    420

gaattgcagc tgaacttcag tgcctaacag tggctggggg gcaagataat gtcatgggag    480

ttaaatactg ctttaggaag aatgatcatg tagttattgc tatgccatat ctggagcatg    540

agtcgttttt ggacattctg aattctcttt cctttcaaga agtacgggaa tatatgctta    600

atctgttcaa agctttgaaa cgcattcatc agtttggtat tgttcaccgt gatgttaagc    660

ccagcaattt tttatataat aggcgcctga aaaagtatgc cttggtagac tttggtttgg    720

cccaaggaac ccatgatacg aaaatagagc ttcttaaatt tgtccagtct gaagctcagc    780

aggaaaggtg ttcacaaaac aaatcccaca taatcacagg aaacaagatt ccactgagtg    840

gcccagtacc taaggagctg gatcagcagt ccaccacaaa agcttctgtt aaaagaccct    900

acacaaatgc acaaattcag attaaacaag gaaaagacgg aaaggaggga tctgtaggcc    960

tttctgtcca gcgctctgtt tttggagaaa gaaatttcaa tatacacagc tccatttcac   1020

atgagagccc tgcagtgaaa ctcatgaagc agtcaaagac tgtggatgta ctgtctagaa   1080

agttagcaac aaaaaagaag gctatttcta cgaaagttat gaatagtgct gtgatgagga   1140

aaactgccag ttcttgccca gctagcctga cctgtgactg ctatgcaaca gataaagttt   1200

gtagtatttg cctttcaagg cgtcagcagg ttgcccctag ggcaggtaca ccaggattca   1260

gagcaccaga ggtcttgaca aagtgcccca atcaaactac agcaattgac atgtggtctg   1320

caggtgtcat atttctttct ttgcttagtg gacgatatcc attttataaa gcaagtgatg   1380

atttaactgc tttggcccaa attatgacaa ttaggggatc cagagaaact atccaagctg   1440

ctaaaacttt tgggaaatca atattatgta gcaaagaagt tccagcacaa gacttgagaa   1500

aactctgtga gagactcagg ggtatggatt ctagcactcc caagttaaca agtgatatac   1560

aagggcatgc ttctcatcaa ccagctattt cagagaagac tgaccataaa gcttcttgcc   1620

tcgttcaaac acctccagga caatactcag ggaattcatt taaaaagggg gatagtaata   1680

gctgtgagca ttgttttgat gagtataata ccaatttaga aggctggaat gaggtacctg   1740

atgaagctta tgacctgctt gataaacttc tagatctaaa tccagcttca agaataacag   1800

cagaagaagc tttgttgcat ccatttttta aagatatgag cttgtgataa tggatcttca   1860

tttaatgttt actgttatga ggtagaataa aaaagaatac tttgtaatag ccacaagttc   1920

ttgtttagag accagagcag gattaataat ttattttaac attttagtgt ttggtggcac   1980

attctaaaat atagattaag aatacttaaa atgcctggga tagttcttgg gactaacaac   2040

atgatcttct ttgagttaaa cctacctaag tagattttag gtgggttcct attaggtcag   2100

atttttagct tccctaatta cctttcactg acatatacag aaaaaggagc agttttagtt   2160

ttaattaatt aaaattaaca gatgtgatga ggattaaatg aatcaaaaga cttaatttgt   2220

agattctttt agagttatga gctaggtata gtttggggaa actcaacctg gtgctggtgc   2280

tcttaacaat tttgtaaatg aagataattt ccttttctag aggtacatat taggcctttt   2340

atgaacacta aaacaatgag gaaatgttgg tcatggggc                          2379


<210>  1020
<211>  1286
<212>  DNA
<213>  Homo sapiens

<400>  1020
ctctttcttc ctgtctgctt ggaaagatgg cgtcccgcaa ggaaggtacc ggctctactg     60

ccacctcttc cagctccacc gccggcgcag cagggaaagg caaaggcaaa ggcggctcgg    120

gagattcagc cgtgaagcaa gtgcagatag atggccttgt ggtattaaag ataatcaaac    180

attatcaaga agaaggacaa ggaactgaag ttgttcaagg agtgcttttg ggtctggttg    240

tagaagatcg gcttgaaatt accaactgct ttcctttccc tcagcacaca gaggatgatg    300

ctgactttga tgaagtccaa tatcagatgg aaatgatgcg gagccttcgc catgtaaaca    360

ttgatcatct tcacgtgggc tggtatcagt ccacatacta tggctcattc gttacccggg    420

cactcctgga ctctcagttt agttaccagc atgccattga agaatctgtc gttctcattt    480

atgatcccat aaaaactgcc caaggatctc tctcactaaa ggcatacaga ctgactccta    540

aactgatgga agtttgtaaa gaaaaggatt tttcccctga agcattgaaa aaagcaaata    600

tcacctttga gtacatgttt gaagaagtgc cgattgtaat taaaaattca catctgatca    660

atgtcctaat gtgggaactt gaaaagaagt cagctgttgc agataaacat gaattgctca    720

gccttgccag cagcaatcat ttggggaaga atctacagtt gctgatggac agagtggatg    780

aaatgagcca agatatagtt aaatacaaca catacatgag gaatactagt aaacaacagc    840

agcagaaaca tcagtatcag cagcgtcgcc agcaggagaa tatgcagcgc cagagccgag    900

gagaaccccc gctccctgag gaggacctgt ccaaactctt caaaccacca cagccgcctg    960

ccaggatgga ctcgctgctc attgcaggcc agataaacac ttactgccag aacatcaagg   1020

agttcactgc ccaaaactta ggcaagctct tcatggccca ggctcttcaa gaatacaaca   1080

actaagaaaa ggaagtttcc agaaaagaag ttaacatgaa ctcttgaagt cacaccaggg   1140

caactcttgg aagaaatata tttgcatatt gaaaagcaca gaggatttct ttagtgtcat   1200

tgccgatttt ggctataaca gtgtctttct agccataata aaataaaaca aaatcttgac   1260

tgcttgctca tttgaaaaaa aaaaaa                                        1286


<210>  1021
<211>  7062
<212>  DNA
<213>  Homo sapiens

<400>  1021
atctgcttaa aggggccgcg agcacttacc tcccgccctg ctccccgccg ccccgccacc     60

gcgtcttcag ggctcccggc aactggctgg aagggcttcc ctcaccctca gtaacagcct    120

gccagcgagg agaggcgagc cgggcgggag gcaaagagga ggcaccgcat ttgtaaaagg    180

caagagagaa aggaaggaag gaaaaaaaaa taacccgagc ggcgcagagt ggactctggt    240

ccgggagagc acgggcgggc gccggaacgt ggacccagag gcaccggaat gcaaacaaag    300

ctcgcgggcg cctgtgcggg gctcgcgggg aagcccagaa agtttgtttt atgatggctt    360

gagtgcgcga gcgtgtgcag gggagcgagg ctgccaagtt tctctctcct gttttgtgat    420

ttggggagag atgtttctcc catgaacaag cggaggcttg ggggctcgtg ctgtgggggg    480

cacctgtctc tcgttttatt tttttggagg aggggtgtaa ctcatcatgt ccaaagtgat    540

ccagaagaag aaccactgga ctagcagggt tcacgaatgc accgtgaagc ggggacccca    600

gggcgagctg ggggtgacgg tgctgggagg cgcggagcac ggggagtttc cgtacgtcgg    660

agcggtggcg gcggtcgagg cagcggggct tcccggcggc ggcgagggcc cgaggctggg    720

cgaaggggag ctgcttctgg aggtgcaggg ggtccgggtg tccggcttgc cccgctatga    780

cgtgctgggg gtcatcgaca gctgcaagga ggccgtcacc ttcaaggccg tcagacaagg    840

aggaaggctg aacaaggacc tgcgacattt tctcaatcag cgattccaga aggggtctcc    900

tgatcatgag ctccagcaga ccataaggga taacctttac cgccatgctg tgccttgcac    960

aacccgatct cccagagaag gagaagtgcc tggcgtggac tataactttc tgactgtgaa   1020

ggagttcttg gacctcgagc agagtgggac tcttctggaa gtcggcacct atgaaggaaa   1080

ctattatggg acacccaagc ctcctagcca gccagtcagt gggaaagtga tcacgacgga   1140

tgccttgcac agccttcagt ctggctctaa gcagtcgacc ccgaagcgaa ccaagtccta   1200

caatgatatg caaaatgctg gcatagtcca cgcggagaat gaggaggagg atgacgttcc   1260

tgaaatgaac agcagcttta cagccgattc tggtgaacaa gaggagcaca ctctccaaga   1320

aacagcatta ccacctgtga atagtagcat catcgctgct cccatcacgg acccttctca   1380

gaagttccct caatacctac ctctttctgc agaggataat ttaggtcctc tacctgaaaa   1440

ctgggagatg gcctatactg aaaatggaga agtctatttt atagaccata acacgaaaac   1500

aacatcttgg ttagaccctc ggtgcctaaa caagcagcag aagccactgg aagagtgtga   1560

agatgatgaa ggggtacaca ccgaggagct ggacagtgaa ctagaactgc ctgctggttg   1620

ggaaaagatt gaagaccctg tctatggtat ctactatgta gaccacatca acaggaagac   1680

acaatatgag aacccggttc tagaagccaa acggaagaag cagcttgagc agcagcagca   1740

gcagcaacag cagcagcaac agcagcagca gcagcagcag cagcagcaga cagaagaatg   1800

gacagaagat cactcagccc ttgtgcctcc tgttattcca aaccaccctc caagcaatcc   1860

agagccagcc agagaagttc cacttcaggg caaacccttt tttacacgaa acccttctga   1920

gttgaaaggc aagttcattc acacaaagct gcggaaaagc agtcgtggct ttggcttcac   1980

ggtggttgga ggggatgaac ctgatgagtt tctccagatc aagagcttgg tcctagatgg   2040

tcctgctgca ttggatggca agatggaaac aggggatgtg attgtaagtg tgaatgacac   2100

ctgtgttttg ggacacacac atgctcaagt tgtgaagatc ttccagtcca tccccattgg   2160

tgccagcgtg gaccttgaac tctgccgagg ttatccattg ccttttgatc cagatgaccc   2220

caatacaagt ttagtgacct cggtagccat tttggataaa gaaccaatta ttgtgaatgg   2280

gcaagagacc tatgattcac cagctagcca cagtagtaaa acaggcaaag tcaatggcat   2340

gaaggatgcc aggccaagca gcccagcgga cgtggcttca aatagttctc atggttatcc   2400

taatgacact gtttctttgg cttcctccat agccactcag ccagaactca taactgttca   2460

tattgtcaaa gggccaatgg gctttggttt tactatcgca gacagtcctg gtgggggtgg   2520

ccaaagagtg aaacagattg ttgacagccc aaggtgccga ggcctgaaag aaggggatct   2580

catagtggaa gttaataaga agaacgtgca ggccctaact cacaaccaag tggtggatat   2640

gctggttgag tgtcctaagg gaagtgaggt cacattgttg gtgcaacgag gagggctgcc   2700

agttcccaag aagagcccaa agtcgcaacc actggaaagg aaagacagcc agaatagttc   2760

tcagcacagt gtttccagcc accgaagcct gcacacagca tccccaagcc acagcacaca   2820

ggtgctcccc gagttcccac ctgcagaggc ccaagctcca gatcaaactg acagctctgg   2880

ccagaaaaaa ccagatcctt ttaaaatctg ggcccagtcc aggagcatgt atgaaaaccg   2940

acttccagat taccaggaac aggacatctt cctctggaga aaagagactg gatttggatt   3000

taggattctg ggtggaaatg aaccagggga acctatttat attggtcaca tcgtaccact   3060

gggtgctgct gatactgacg gccgcctgag gtctggagat gaattaatct gtgtggatgg   3120

gacgccagta attggaaaat cacaccagct tgtggtccag cttatgcaac aagctgccaa   3180

gcaaggccac gtcaatctca cggtgcggcg taaagtggtt tttgcggtgc ccaaaaccga   3240

gaacgaggtg ccctcgccag cctcctctca tcacagtagc aaccagccgg cctcgctgac   3300

agaagagaag cgcactccgc agggcagcca gaactcgctg aacacggtga gctcgggcag   3360

cggcagcacc agcggcatcg gcagtggcgg cggcgggggc agcggcgtgg tcagcaccgt   3420

ggtgcagccc tacgacgtgg agatccggcg cggggagaac gagggcttcg gcttcgtcat   3480

cgtgtcctcg gtgagcaggc ccgaagcagg cacgaccttt ggcaatgcat gtgtggctat   3540

gcctcacaaa ataggtcgga ttattgaggg gagccctgct gaccgctgtg gcaagctgaa   3600

agtaggagac cggatcttgg cagtaaatgg atgttccatc accaacaaat cccattcaga   3660

cattgtgaac ctaatcaagg aagcgggaaa cacagttacc ctccgcatca ttcctgggga   3720

tgagtcctcg aatgccacct tgctgaccaa tgcagagaag attgccacca tcaccaccac   3780

acacacccct tctcagcaag ggacccagga gacaaggaat accaccaaac caaagcagga   3840

atctcaattt gagttcaaag caccccaagc aacacaggag caagattttt acactgtgga   3900

actggaaaga ggagccaagg gatttggctt tagccttcga ggaggccgag agtataacat   3960

ggacctctat gttctgcgct tagcagagga cggtcctgcg gagaggtgtg gaaagatgag   4020

gattggtgat gaaattttag agatcaatgg tgagaccacc aaaaacatga agcattctcg   4080

agctatagaa ctgattaaga atggtggccg cagagttcgt ctgtttctga agcggggaga   4140

cggctcagta ccagaatatg accccagcag cgaccgccac ggccccgcca ccggtccaca   4200

aggtgttccg gaagtgaggg ccgggcccga ccgccggcag catccgtcat tggagtccag   4260

ttacccaccc gatcttcaca aatcatcacc acatggggaa aagcgggcac acgcaaggga   4320

tccgaaaggc agcagagagt atagcagaca acccaatgaa caccacacct ggaatgggac   4380

ttcgaggaaa cccgacagcg gggcatgccg acccaaggac cgggcgccgg agggacggag   4440

ggacgcgcag gccgagcgcg cggcagccgc caacggcccc aagaggcggt ccccagagaa   4500

gcggagggag ggcacccgca gcgccgacaa cactttggag aggagggaga agcacgagaa   4560

gagacgagac gtctctccgg agcggaggcg agagcggtca cccacccgca ggagagacgg   4620

ctcccccagc cggcggagac ggtctctgga gagactcctg gagcagagga ggtcccccga   4680

gcgcaggaga gggggctcgc ccgagcgcag ggccaagtcc accgaccgga ggcgcgcacg   4740

ctcccccgag cgcaggagag agcggtccct ggacaaaagg aacagagagg acagagccag   4800

ccaccgagaa agggaagagg cgaatctgaa acaggatgcc ggcagaagtt ccagacatcc   4860

cccggagcag agaaggcgac cttacaaaga atgtagcacc gacctcagta tctgagacgc   4920

tgagtcacat tccaaccttt accgtgtcaa aggttctaag aggaaagtca caaacctgaa   4980

attatttagt ttcttaccta atgaagcatc tgacacctga tgatcctatg aataacaaca   5040

aacattttat gcatttgaaa tcttataaga aaaaatatat atgaaaagta ttgtgcctga   5100

tgtatcatat taaagaaagt atttttaaat gcatactttt ttggaaatta tttgccaaat   5160

gctggcccaa agggatataa attttgtttc tacgtaacct gtagaatcgt caagaattgt   5220

tcccgttttg gggcaatctt tttctctcct ggttaaatgg ggctgttgat cattttctct   5280

acgtaaggga atttattgat taagtttaat taatttgata tagactgtca tgtagtgatg   5340

tagtgctata ctgtagtcgg aagtttttct taaaagcaaa gagcaaaaat gcaaagtttt   5400

atttgtaaaa gctgaggacc cttggggatg gattaggttt gccgatgatc ctaaaagtaa   5460

gcaaactgta tgacaagact actattgcaa atgaaggata tttatagcta aactgcgcag   5520

cacaaagaag ttttatattg tgagttatag ttggttcaga aaacagtttg tactctccct   5580

ggcccaggaa ggcacacaga caaaaatgtc ggccactttt actcaaatac agcccaagca   5640

cagacagtca ggttcgtgat catcaccaac atctgataaa atctcattga aggcaatgcc   5700

atcacagctt tgctcaatta ctacgaggaa gagacaacaa gcatctttcg tgttgtctcg   5760

tctgattgga ggctgaatag tagatggaat ggggggacag tgtgcctggt gtgaggaaga   5820

cgtaagatcc ccaatttgga aagcatgccc ccctcccttt tagtagaagc ccatggttgc   5880

cctttgccaa actggggagg aggcaatgag ccttggtgga aggaacctct ctgttgatat   5940

ttaaagaagt gagggctgtg ggtattcatt gttagaaatg ccaatttcac tttgaaacca   6000

tagtccaagt ctctaggttg gtagaaggga aaggaaggaa gtggtcccag tgattctagg   6060

tctggttggg aaacttctgc ctcatgactc tgtcctttga gtcctttgga cagcagcaca   6120

aaacataaca atttttattt ttaaacagac ccattctttt tgatcccaca ggagctgtgg   6180

ttgggtcggc cgtagccccg ggatgtggtt taagtggatt actgcctagc tgagccaaaa   6240

tgtttgcttg tacctgttgg accactacag caaaccgctg cttacagtgc attgtgtatt   6300

tctgtagtac tgttttgcat tttccataga gacagaaaac tttgcaagtc aatcactgtt   6360

gttcccatgg tactgtaaga aaaaaaaaaa ggaaaaagaa aaaaaaaaag aaaaccagcc   6420

aatcattgcg tgtacagagc taaaaattgt aattaataga gcctgttggg aaaaaaaaga   6480

aaacaactgt tgcctttttt tcttgtataa aagagaattt atgacaaaat ttagctgtga   6540

ggaatgtgat acgtgtttat atttctgaat atggaacaaa ttgattcatg gggatatatt   6600

ttaatgtaaa ctaaatcagg tatgtaaagt tgttttaaaa tgggagacta tataagtaat   6660

tctctaaagc tttagttggt ttgaatatca tcatttcctc catggtgagc ctgcttgtga   6720

attattaagc acttgtttgc attctctgtt cttcactcat ttatttcttg cagtgtgcta   6780

tggacttaat gctctttctg tattgatgaa aagcagtatg tgggccaatc tttttataaa   6840

acactatgca tatataaata ttacattgtt catagcttta tttgacttat gggtttatac   6900

ataacattag aatgagtagc tgtagttgtg tggacattta taaaacaagt tcctttcctg   6960

gaacagacac aatatacatt ctgtagctaa aaaggaggga aaagtctgtg aatgctattt   7020

ttattattaa agttttccat acaaagcata cattgagctg ta                      7062


<210>  1022
<211>  1635
<212>  DNA
<213>  Homo sapiens

<400>  1022
cattcaaccg ccgctctgcg cggcgccggc tccgcccccg tcgggtgttt gtggtggggc     60

tgcggagtcg ccgatcccgc cggaagcgcc aggacaatgg ggacccggga cgacgagtac    120

gactacctat tcaaagtggt gctcatcggg gactcaggcg tgggcaagag caacctgctg    180

tcgcgcttca cccgcaacga gttcaacctg gagagcaaga gcaccatcgg cgtggagttc    240

gccacccgca gcatccaggt ggacggcaag accatcaagg cgcagatctg ggacaccgct    300

ggccaggagc gctaccgcgc catcacctcc gcgtactacc gtggtgcagt gggcgccctg    360

ctggtgtacg acatcgccaa gcacctgacc tatgagaacg tggagcgctg gctgaaggag    420

ctgcgggacc acgcagacag caacatcgtc atcatgctgg tgggcaacaa gagtgacctg    480

cgccacctgc gggctgtgcc cactgacgag gcccgcgcct tcgcagaaaa gaacaacttg    540

tccttcatcg agacctcagc cttggattcc actaacgtag aggaagcatt caagaacatc    600

ctcacagaga tctaccgcat cgtgtcacag aaacagatcg cagaccgcgc tgcccacgac    660

gagtccccgg ggaacaacgt ggtggacatc agcgtgccgc ccaccacgga cggacagaag    720

cccaacaagc tgcagtgctg ccagaacctg tgacccctgc gcctccaccc agcgtgcgtg    780

cacgtcctcc gcccgccccc gccacggtat cctctggccc ctccctgctg tccctctgtg    840

gccggctcgt tccagccctc ccagtgagct ctgcacggcc gggccggggc ccaggaagga    900

caggagccag tgctaccccg tcctgcccgg ggaaaagcta gaagccccgg tttgctgcac    960

ccatgaaact cgggtcccca cagcgtcttg gcggggtggg gagggcggca ggatggacgg   1020

ggctggccag aggcgaggag gacgggcgga cggcgccgcc ttctcccctt ttccttggcc   1080

gactctaggg agcgattgcc tccctccctc tgtgaccggg tggcccagcc agcccgtcgt   1140

ccccacccag aaccgtgctc tgggccaaag cccgaagaac caggcagcgg gggccggggc   1200

aggcggaccc cccgggctct cagcgcccac ccgctcctcc gcacacagca gctcgcacag   1260

gcctcccacc tctgcctgtt gattgatgca gggagaagcc cgtccccccc tctcccctct   1320

cccctcccct ctcctgcacg caacgcgccc tctcggccct ccctgtcccc ctcctctgtc   1380

tcgtctcccc atctggtctg gaacctgttt gcaagtgaag caatatctcc gtgttttgta   1440

tatacaaccg ctcttgtagc ctttggtttt tgttaatgta gagaaacaca gattctttat   1500

acactttgta agatttacgc caaaccccag ctctcgatct cttcttctcc ctgtggcccc   1560

tgcgctgttg ccccgtcccc gtcaccccgc ccgttactga aatgtataat ctgacttcct   1620

gtacagaaaa aaaaa                                                    1635


<210>  1023
<211>  1423
<212>  DNA
<213>  Homo sapiens

<400>  1023
catggcttcc gaggagctgt acgaggtaca tctccgttca tggatgcatt aacagccaat     60

gggacaacca acatacagac atctgttaca ggagtgactg ccagcaaaag gaaatttatt    120

gacgacagaa gagaccagcc ttttgacaag cgattgcgtt tcagcgtgag gcaaacagaa    180

agtgcctaca gatacagaga tattgtggtc aggaagcagg atggcttcac ccacatcttg    240

ttatccacaa agtcctcaga gaataactca ctaaatccag aggtaatgag agaagtccag    300

agtgctctga gcacggccgc tgccgatgac agcaagctgg tactgctcag cgccgttggc    360

agcgtcttct gttgtggact tgactttatt tattttatac gacgtctgac agatgacagg    420

aaaagagaaa gcactaaaat ggcagaagct atcagaaact tcgtgaatac tttcattcaa    480

tttaagaagc ccattattgt agcagtcaat ggcccagcca ttggtctagg agcatctata    540

ttgcctcttt gcgatgtggt ttgggctaat gaaaaggctt ggtttcaaac accctatacc    600

accttcggac agagtccaga tggctgttct accgttatgt ttcccaagat aatgggagga    660

gcatctgcaa acgagatgct gctcagtgga cggaagctga cagcgcagga ggcgtgtggc    720

aagggcctgg tctcccaggt gttttggccc gggacgttca ctcaggaagt gatggttcgc    780

attaaggagc ttgcctcgtg caatccagtt gtgcttgagg aatccaaagc cctcgtgcgc    840

tgcaacatga agatggagct ggagcaggcc aacgagaggg agtgtgaggt gctgaagaaa    900

atctggggct cggcccaggg gacggactcc atgttaaagt acatgcagag gaagatcgat    960

gagttctgag tgtcgggctg cccactggtg acaccgggat cgggctgagc aggagaacat   1020

caccggctcc agttcccctg atccattctc acagcctgaa acaagctcac ccgtagctta   1080

cgcttggaag taggactggg aacatccacg ctatttatta tcgaggagtt ttaaagtact   1140

gtaactttaa aataaataac tacaaagctt ctttgtccaa acgtcattat tttatactta   1200

tatacacgca ggtgtaaaag tataaaggtg agcactagac tgctcttaga agctctaatt   1260

tttgttttct ttggctagta ctgtataaaa aacagaattg tgttttattg gttttggatg   1320

acagaaaagt ctggaataat gtttgttttc ctcatttctt ccttctagaa cacagaatct   1380

aaaggggtat tagccagcct cgcctccctg ccccacgtag aga                     1423


<210>  1024
<211>  1268
<212>  DNA
<213>  Homo sapiens

<400>  1024
gccctctcac cccgctgcct ctaggttctg ggaagatggc gaaggtctca gagctttacg     60

atgtcacttg ggaagaaatg agagataaaa tgagaaaatg gagagaagaa aactcaagaa    120

atagtgagca aattgtggaa gttggagaag aattaattaa tgaatatgct tctaagctgg    180

gagatgatat ttggatcata tatgaacagg tgatgattgc agcactagac tatggtcggg    240

atgacttggc attgttttgt cttcaagagc tgagaagaca gttccctggc agtcacagag    300

tcaagcgatt aacaggcatg agatttgaag ccatggaaag atatgatgat gctatacagc    360

tatatgatag gattttacaa gaagatccaa ctaacactgc tgcaagaaag cgtaagattg    420

ccattcgaaa agcccagggg aaaaatgtgg aggccattcg ggagctgaat gagtatctgg    480

aacaatttgt tggagaccaa gaagcctggc atgaacttgc agaactttac atcaatgaac    540

atgactatgc aaaagcagcc ttttgtttag aggaactaat gatgactaat ccacacaacc    600

acttatactg tcagcagtat gctgaagtta agtataccca aggtggactt gaaaacctcg    660

aactttcaag aaagtatttt gcacaggcat tgaaactgaa caacagaaat atgagagctt    720

tgtttggact ttatatgtcg gcaagtcata ttgcttctaa tccaaaagca agtgcaaaaa    780

cgaaaaagga caacatgaaa tatgctagtt gggcagctag tcaaataaac agagcttatc    840

agtttgcagg tcgaagtaag aaggaaacca aatattctct taaggctgtc gaagacatgt    900

tggaaacatt gcagatcacc cagtcttaag gtttcaaaaa ctctttgaca ttagatttca    960

caactgcaca attgaactta ttggcctgta acttatttac taaatgctca gtgctattta   1020

tatactacag taattttctg ttaagaaggc agttgtaaag aatgtgttta tataaaccta   1080

aaaatgcctt ttactgctaa gtggggagat gggggaaatc catggaagag agatttaaga   1140

cttattgatt gtacatcagt ctcttcatat cacatataca tgtatatata taaaactcta   1200

atgtagtata accttgttaa ataaaccatg atgatttaca aaaaaaaaaa aaaaaaaaaa   1260

aaaaaaaa                                                            1268


<210>  1025
<211>  13671
<212>  DNA
<213>  Homo sapiens

<400>  1025
atgaaagtag acaggactaa actgaagaag acacctactg aggctcctgc agactgcaga     60

gccttaatag acaaactcaa agtttgtaat gatgagcaac ttctcttgga actgcagcag    120

atcaaaacat ggaacattgg aaagtgcgag ttatatcact gggtggacct gttggaccgc    180

ttcgatggaa tactggcaga tgctggacag acagtggaga atatgtcatg gatgctcgta    240

tgtgataggc cagaaagaga gcaactgaaa atgcttctct tggctgtgtt gaacttcaca    300

gccttgctca ttgagtacag cttttcccgg catctgtaca gttccataga gcatttgaca    360

actttattgg cttcctctga tatgcaagtg gtgctggcag tcctcaatct cctatatgta    420

tttagcaaaa gatcaaacta catcactcgt ctgggatctg acaagaggac cccgctgcta    480

actcggctac aacatttggc agagagctgg ggtggaaagg agaatggctt tggacttgca    540

gaatgttgca gagacttgca tatgatgaaa tatccaccca gtgcaactac actacacttt    600

gaattctatg cagatcctgg ggccgaggtc aaaattgaga aaaggacaac tagtaacaca    660

ctacattata ttcacataga gcaacttgac aagatttcag aaagcccttc tgaaatcatg    720

gaatctctta ccaaaatgta cagcattcct aaggataagc agatgctgtt atttacacac    780

atacgactgg cccatggctt ttctaatcac aggaagcgat tgcaggcagt tcaggccaga    840

ctgcatgcaa tatctatatt agtgtattcc aatgccttgc aggaatcagc aaacagtatc    900

ttgtataatg gcttgataga ggagttggta gatgtccttc agataacgga taagcagctt    960

atggagatta aagcagcttc tttacgaaca ttaacatcaa ttgtccactt ggagagaact   1020

cccaaactca gcagtattat tgactgtact ggaactgcct cctaccatgg atttttgcca   1080

gtgcttgtaa ggaactgtat ccaggccatg attgatcctt ccatggatcc ataccctcac   1140

cagtttgcca ctgctctctt ctctttttta taccatctgg ccagctacga tgctggtggt   1200

gaagccttgg tctcctgtgg aatgatggaa gccttattga aggtcataaa gtttcttggc   1260

gatgaacagg accagataac atttgtcacc agagccgtca gagtggttga ccttatcacc   1320

aacctggata tggcagcttt tcaatcccat agtggacttt ctatcttcat ttatagactt   1380

gagcatgaag tagatttgtg ccgaaaagaa tgtccgtttg tgatcaagcc aaagatccag   1440

agacccaata ctacacaaga aggagaggaa atggaaactg atatggatgg agtccagtgt   1500

attccacaac gagcagcact tctgaaatcc atgttgaatt tcctcaagaa ggccatccaa   1560

gaccctgctt tctcagatgg catacgacat gtgatggatg gttctctgcc tacctccctg   1620

aaacacatca tcagcaatgc agaatactat ggcccatcac tcttcctcct agctactgaa   1680

gtggtgactg tgtttgtatt tcaagaacca tcactgctct cctcactcca ggacaatgga   1740

ttgacagatg tcatgctgca tgcactgctt atcaaagatg ttcctgctac ccgtgaagtc   1800

cttggctccc tcccaaatgt attcagtgca ctctgtttga atgcccgagg tcttcagtct   1860

tttgttcagt gtcagccttt tgaacgcctc ttcaaagttc ttctgtctcc agattacctc   1920

ccagccatgc ggaggaggag aagttctgat ccccttgggg atactgcatc caacctgggg   1980

agtgctgtcg atgagctcat gagacatcag cccaccctta aaacagatgc aacgactgcc   2040

atcatcaagt tacttgaaga aatctgtaat cttggaaggg accccaaata catctgtcag   2100

aagccatcaa tccagaaggc agatggcact gccactgctc ctcccccaag gtctaatcat   2160

gccgcagaag aagcctctag tgaggatgag gaggaagagg aagtacaggc catgcagagc   2220

tttaattcta cccagcaaaa tgaaactgag cctaatcagc aggttgttgg tacagaggaa   2280

cgtattccta ttcccctcat ggattacatc cttaatgtga tgaaatttgt ggaatctatt   2340

ctgagcaaca atacaacaga tgaccactgc caggaatttg tgaatcagaa aggactgttg   2400

cctttggtta ccattttggg tcttcccaat ctgcccattg actttcccac atctgctgcc   2460

tgtcaggctg ttgcaggtgt ctgcaaatcc atattgacac tgtcacatga acccaaagtc   2520

cttcaagagg gtctccttca gttggactcc atcctctcct ccctggagcc cttacaccgc   2580

cccattgaat cccctggggg ctcagtgttg ttgcgagaac tggcttgcgc aggcaatgtt   2640

gctgatgcta ccctctcagc ccaggccaca cctctgctgc atgcactcac tgctgcccat   2700

gcctacatca tgatgtttgt tcatacttgc agagttggac agagtgaaat tcgttccatc   2760

tccgtaaacc agtggggctc tcaattgggt ctgagtgttt tgagcaagct gagccagtta   2820

tactgttccc tggtgtggga aagcactgtc ctcctctctc tgtgtacccc aaacagccta   2880

ccatctgggt gtgaatttgg ccaggcagat atgcagaaac tggttccaaa ggatgagaag   2940

gcaggtacga cccagggcgg aaaaagatca gatggggaac aggatggagc agctggaagt   3000

atggatgctt ctacccaggg cttattagaa ggcattgggc tagatggtga cacattggct   3060

cccatggaga cagatgaacc tactgcttca gactctaagg gcaaatctaa aatcacacca   3120

gcaatggctg ccagaattaa gcaaatcaag cctttgttat cagcttcctc cagattaggc   3180

cgagcacttg ctgagctatt tggacttctt gttaaacttt gtgtgggatc tcctgtccgc   3240

cagagaagga gccatcatgc tgccagcacc actacagcac cgacacctgc cgcgcgatca   3300

acagcctcag ctctcactaa gctcttgact aaggggttat cttggcagcc cccaccatat   3360

acacctactc cccgattcag gctgacattc ttcatctgtt cagttggttt cacatcccca   3420

atgctgtttg atgagaggaa gtatccctac cacctcatgc tgcaaaaatt tctctgctcc   3480

ggaggccaca atgctctttt tgaaactttc aactgggctc tgtccatggg aggtaaagtt   3540

cctgtttctg agggattgga acactcagac ttgcctgatg gcacaggaga attcctagat   3600

gcctggctta tgctggtgga gaagatggtg aatcccacca cggtgcttga atctccacat   3660

tcgctgcctg ccaaattgcc tggaggtgtc cagaactttc cccagttcag tgcactgcgc   3720

ttccttgtgg taactcagaa agcagccttt acttgcatca aaaacttatg gaaccggaaa   3780

cccctgaagg tatatggtgg acgaatggct gaatcgatgc tggccattct atgccacatc   3840

ctccgaggag aacctgtgat tcgagagaga ctaagcaagg agaaggaggg gtctcgagga   3900

gaagaggata cagggcaaga ggaaggtggc tcccgccggg aacctcaagt caaccagcaa   3960

caactgcaac agctcatgga catgggcttc acaagggaac atgcaatgga ggcactgttg   4020

aacaccagca ccatggagca ggccacagag taccttttaa cccaccctcc tccaatcatg   4080

ggaggagttg ttcgggatct cagcatgtct gaagaggacc agatgatgag agcaattgct   4140

atgtctctgg gacaggatat tccaatggat caaagggcag agtcacctga ggaagttgct   4200

tgccggaagg aggaagagga acggaaagct cgggaaaagc aggaggagga agaggctaaa   4260

tgtctagaga agttccagga tgctgacccg ttggaacaag atgagctcca cactttcaca   4320

gatactatgt tgccaggctg cttccacctt cttgatgagc tgccagacac agtataccgt   4380

gtgtgtgacc tgatcatgac agcaatcaaa cgtaatggag cagattatcg tgacatgatt   4440

ctgaagcaag tagtcaatca ggtgtgggaa gctgctgatg tattgatcaa agctgctctt   4500

cccctgacaa caagtgacac aaaaaccgtg tcagagtgga taagtcagat ggccacactg   4560

ccccaggcct ccaatttggc tactagaatc ttgcttttaa cgctactttt tgaggagttg   4620

aagctacctt gtgcttgggt ggttgaatca agtggcatcc ttaatgtcct aatcaaactc   4680

ttggaagtgg ttcagccctg cctccaggca gccaaggagc agaaggaagt ccagacccca   4740

aagtggatca caccagtgtt gctcctgatt gatttctatg aaaagacagc catctcctca   4800

aaaaggagag cccagatgac taagtacctg caatccaaca gcaacaactg gcgctggttt   4860

gatgatcgct ctgggcgttg gtgtagttac agtgcaagca acaatagcac tattgattct   4920

gcctggaaat ctggagagac aagcgtgcga ttcactgcag gccgaagaag atacacggtc   4980

caattcacta caatggtgca ggttaatgag gaaacaggga accgacgccc tgtgatgctg   5040

actctcctca gggtacctcg gctgaataaa aattcaaaaa acagcaatgg acaggaacta   5100

gagaagacgc tggaagaaag caaagaaatg gatatcaaac gtaaagaaaa taaaggcaat   5160

gatacccctt tggccctaga gagtacaaac actgaaaagg agacaagcct ggaggaaaca   5220

aaaatcgggg agatcctgat ccagggcttg acagaagata tggtgactgt tttaatccgg   5280

gcctgcgtga gcatgctggg agtccctgtg gacccagata ctttgcatgc cacccttcgt   5340

ctctgtctga ggctcacccg ggaccacaaa tatgccatga tgtttgcaga actgaagagt   5400

acccgcatga tcttgaattt gacccagagc tcaggcttca atgggtttac tcccctggtc   5460

acccttctct taagacacat cattgaggac ccctgtaccc ttcgtcatac catggaaaag   5520

gttgttcgct cagcagctac aagtggagct ggtagcacta cctctggtgt tgtgtctggc   5580

agcctcggct ctcgggagat caactacatc cttcgtgtcc ttgggccagc cgcatgccgc   5640

aatccagaca tattcacaga agtggccaac tgctgtatcc gcatcgccct tcctgcccct   5700

cgaggctcag gaactgcttc agatgatgaa tttgagaatc ttagaattaa aggccctaat   5760

gctgtacagc tggtgaagac cacccctttg aagccctcac ctctgcctgt catccctgat   5820

actatcaagg aagtgatcta tgatatgctg aatgctctgg ctgcatacca tgctccagag   5880

gaagcagata aatctgatcc taaacctggg gttatgaccc aagaggttgg ccagctcctg   5940

caagacatgg gtgatgatgt ataccagcag taccggtcac ttacgcgtca gagcagtgac   6000

tttgatacgc agtcaggttt ttccattaat agtcaggtct ttgctgcaga tggtgcctcc   6060

actgagactt ccgcatctgg gacctcccaa ggagaggctt caactccaga ggagtctcga   6120

gatgggaaga aagataaaga aggggaccgg gcctctgagg aaggcaaaca gaaaggcaag   6180

ggcagcaaac ctttaatgcc tacctccact atccttcgtc ttctggcaga gttggtgagg   6240

tcctatgttg gtattgctac cctgattgcc aactacagct acactgtggg ccagtctgaa   6300

ctgatcaaag aggactgcag tgtgctagct tttgttctgg accacctgct cccacatacc   6360

cagaatgcag aagacaagga cacccctgcc ttggcccgcc tgttcctcgc aagcctggct   6420

gctgcaggga gtggcacaga tgcccaggtg gccctagtga atgaagtaaa agcagccctt   6480

ggacgggcac tggctatggc tgagagtaca gagaaacatg ccaggcttca ggcagtgatg   6540

tgtatcatca gtactatcat ggagtcctgc ccctccacct ccagcttcta cagcagtgcc   6600

acagcgaaga cccagcacaa tggcatgaac aacatcattc ggcttttcct gaagaaggga   6660

ctggttaatg acctggccag agtacctcac agcttagacc tgtccagtcc caacatggcc   6720

aacacagtca atgctgctct gaagcctttg gaaacacttt cccggattgt gaaccagccc   6780

agtagccttt ttggcagcaa gagtgcttct agcaagaaca agtctgagca ggatgcccaa   6840

ggagcctctc aagattccag tagcaaccag caggacccag gcgagcctgg ggaagcagaa   6900

gtgcaggagg aggatcatga tgtcactcag acagaggtgg cagatgggga tatcatggat   6960

ggggaggctg aaaccgactc agtggtgatt gctgggcagc ctgaggtgct cagttcacaa   7020

gagatgcagg ttgagaatga gctggaggac ctgatagatg agttgcttga gagggatggc   7080

ggatctggga acagtacaat tatagtgagc agaagtggag aggatgaatc acaagaggac   7140

gtgctgatgg atgaagctcc ttccaacctc agccaagctt ccaccttgca ggccaaccga   7200

gaagattcca tgaatatcct ggaccctgag gatgaggagg agcacactca ggaagaggac   7260

agcagtggca gtaacgagga tgaggatgat agtcaggatg aagaggagga ggaggaggaa   7320

gatgaggaag atgatcagga ggatgatgaa ggtgaagagg gagatgaaga cgatgacgac   7380

gatggctctg agatggaatt ggatgaggat tatcctgata tgaacgcttc tcccttggtc   7440

cgatttgagc gctttgaccg ggaggatgat ctcatcattg agtttgacaa catgttctcc   7500

agtgctacag acatcccccc atccccagga aatatcccta ccacccatcc actgatggtg   7560

cgccatgcag accacagttc tctgacactg ggcagtggct cttcaacaac tcgtctcacc   7620

cagggcatcg ggcgcagtca gaggacccta aggcagctga cggccaatac tggccacacc   7680

attcatgttc actaccctgg gaatcgccag cccaaccctc ctcttatact gcagaggttg   7740

cttggtccct cagctgctgc tgacatcctt cagctgagca gcagccttcc cctacaaagc   7800

cggggtcggg cccgcctcct ggtaggcaac gatgacgtcc acatcatcgc ccgttctgat   7860

gatgagctgc tggatgactt tttccatgat cagagcacag ctaccagcca agcaggaacc   7920

ctgtccagca tccccacagc cctgacccgc tggacagaag aatgcaaagt tctcgatgct   7980

gagagcatgc atgactgtgt ttcagtggtt aaagtgtcca ttgtcaatca cctggaattc   8040

ctgagggatg aggagctgga agaaaggcga gagaagcgca ggaaacaact ggctgaggaa   8100

gaaacaaaga taactgataa aggcaaagaa gataaggaga acagggatca gagtgcacag   8160

tgtactgcat ctaagtcaaa tgactccact gaacagaatc tctcagatgg gacgcctatg   8220

cctgacagct acccaacaac cccatcttca actgatgcag ctacatctga gtccaaggag   8280

acccttggca ctctgcaatc ctcacaacag caaccaacac tcccaacccc accagctttg   8340

ggagaggttc ctcaggagct gcagtctcca gctggagaag ggggcagctc tacacagcta   8400

ttgatgcctg tagagccaga ggaattgggt cccacaaggc caagtgggga agcagaaaca   8460

actcagatgg agttatcccc agctcccact ataacctcac tttccccaga gagagctgag   8520

gattctgatg cactgacggc tgtcagcagt cagctagaag gctctcctat ggatacaagc   8580

agcctggctt cctgtacctt agaggaggct gtgggtgaca cttcagcagc tggcagttct   8640

gagcagccca gagcaggcag ctccactcct ggggatgccc caccagctgt ggcggaagtg   8700

caaggcagga gtgatgggtc aggggaatct gcccagccac ctgaggacag ctccccacct   8760

gcatcctctg agagctcttc caccagagat tctgccgtgg ccatttctgg agcagattcc   8820

cgaggaatcc tagaagagcc gttgccttca acaagcagtg aagaagaaga tccccttgcg   8880

ggtatcagtc tccctgaagg tgtggacccc tcttttctgg ctgccctgcc tgatgacatc   8940

cgtcgggaag ttctacagaa ccagctaggc attcgtccac caacccggac tgccccctcc   9000

acaaatagct cagcgcctgc agtggtgggg aatcctggtg tgactgaagt gagccctgag   9060

tttctggctg ccctgcctcc agccattcag gaggaagtac tggcacagca gagagctgag   9120

cagcagcgac gagaactagc acagaatgcc agctcagaca cccctatgga ccctgtgacc   9180

ttcatccaga ctctgccctc agacctgcgc cgtagtgtcc tagaggatat ggaggacagt   9240

gtgttagctg tgatgccacc tgacattgca gctgaggctc aagccctgag acgagagcaa   9300

gaagcccggc agcgacagct catgcatgag cgtctgtttg ggcacagtag cacctccgca   9360

ctctctgcta ttctccgaag cccggctttc accagtcgct taagtggcaa ccgtggggtc   9420

cagtatactc gccttgctgt gcagagaggt ggcaccttcc agatgggggg tagcagcagc   9480

cataacaggc cttctggcag taatgtagat actctcctcc gcctccgagg acggctcctt   9540

ctggaccacg aagccctttc ttgtctcttg gtcctacttt ttgtggatga gccaaagctc   9600

aatactagcc gtctacaccg agtactgaga aatctctgct accatgccca gacccgccac   9660

tgggtcatcc gcagtctgct ctccatcttg cagcgcagca gtgagagtga gctatgcatt   9720

gaaacaccca aactcactac aagtgaggaa aagggcaaaa agtcgagcaa gagctgtggg   9780

tcaagtagcc atgagaaccg tcccctggac ctgctacaca agatggagtc aaagagctcc   9840

aaccagcttt cctggctctc agtatccatg gatgcagccc taggctgcag gactaatata   9900

tttcagatcc agcgttcagg ggggcgtaaa cataccgaga agcatgcaag cggtggctcc   9960

accgtccaca tccatcccca agctgctcct gttgtctgca gacacgtttt ggatacactc  10020

attcaattgg ccaaggtatt tcccagccac ttcacacagc agcggaccaa agaaacaaac  10080

tgtgagagtg atcgggaaag gggcaataag gcctgtagcc catgctcctc acagtcctcc  10140

agcagtggca tttgcacaga cttctgggac ttattggtaa aactggacaa catgaatgtc  10200

agccggaaag gcaagaactc cgtgaagtca gtgccagtga gcgctggcgg tgagggggaa  10260

acctctccat acagcctcga ggcctctcca ctggggcagc tcatgaacat gttgtcacac  10320

ccagtcatcc gccggagctc tctcttaact gagaaactcc tcagactcct ttctctcatc  10380

tcaattgctc tcccagaaaa caaggtgtca gaagcacagg ctaattctgg cagcggtgct  10440

tcctccacca ccactgccac ctcaaccaca tctaccacca ccaccactgc cgcctccacc  10500

acgcccacac cccctactgc acccacccct gtcacttctg ctccagccct ggttgctgcc  10560

acggctattt ccaccattgt cgtagctgct tcgaccacag tgactacccc cacgactgct  10620

accactactg tttcaatttc tcccactact aagggcagca aatctccagc gaaggtgagt  10680

gatgggggca gcagcagtac agactttaag atggtgtcct ctggcctcac tgaaaaccag  10740

ctacagctct ctgtagaggt gttgacatcc cactcttgtt ctgaggaagg cttagaggat  10800

gcagccaacg tactactgca gctctcccgg ggggactctg ggacccggga cactgttctc  10860

aagctgctac tgaatggagc ccgccatctg ggttataccc tttgtaaaca aataggtacc  10920

ctgctggccg agctgcggga atacaacctc gagcagcagc ggcgagccca atgtgaaacc  10980

ctctctcctg atggcctgcc tgaggagcag ccacagacca ccaagctgaa gggcaaaatg  11040

cagagcaggt ttgacatggc tgagaatgtg gtaattgtgg catctcagaa gcgacctttg  11100

ggtggccggg agctccagct gccttctatg tccatgttga catccaagac atctacccag  11160

aagttcttct tgagggtact acaggtcatc atccagctcc gggacgacac gcgccgggct  11220

aacaagaaag ccaagcagac aggcaggcta ggttcctccg gtttaggctc agctagcagc  11280

atccaggcag ctgttcggca gctggaggct gaggctgatg ccattataca aatggtacgt  11340

gagggtcaaa gggcgcggag acagcaacaa gcagcaacgt cggagtctag ccagtcagag  11400

gcgtctgtcc ggagggagga atcacccatg gatgtggacc agccatctcc cagtgctcaa  11460

gatactcaat ccattgcctc cgatggaacc ccacaggggg agaaggaaaa ggaagaaaga  11520

ccacctgagt tacccctgct cagcgagcag ctgagtttgg acgagctgtg ggacatgctt  11580

ggggagtgtc taaaggaact agaggaatcc catgaccagc atgcggtgct agtgctacag  11640

cctgctgtcg aggccttctt tctggtccat gccacagagc gggagagcaa gcctcctgtc  11700

cgagacaccc gtgagagcca gctggcacac atcaaggacg agcctcctcc actctcccct  11760

gcccccttaa ccccagccac gccttcctcc cttgacccat tcttctcccg ggagccctca  11820

tctatgcaca tctcctcaag cctgccccct gacacacaga agttccttcg ctttgcagag  11880

actcaccgca ctgtgttaaa ccagatccta cggcagtcca cgacccacct tgctgatggg  11940

ccttttgctg tcctggtaga ctacattcgt gtcctcgact ttgatgtcaa gcgcaaatat  12000

ttccgccaag agctggagcg tttagatgag gggctccgga aagaagacat ggctgtgcat  12060

gtccgtcgtg accatgtgtt tgaagactcc tatcgtgagc tgcatcgcaa atcccccgaa  12120

gaaatgaaga atcgattgta tatagtattt gaaggagaag aagggcagga tgctggcggg  12180

ctcctgcggg agtggtatat gatcatctct cgagagatgt ttaaccctat gtatgccttg  12240

ttccgtacct cacctggtga tcgagtcacc tacaccatca atccatcttc ccactgcaac  12300

cccaaccacc tcagctactt caagtttgtc ggacgcattg tggccaaagc tgtatatgac  12360

aaccgtcttc tggagtgcta ctttactcga tccttttaca aacacatctt gggcaagtca  12420

gtcagatata cagatatgga gagtgaagat taccacttct accaaggtct ggtttatctg  12480

ctggaaaatg atgtctccac actaggctat gacctcacct tcagcactga ggtccaagag  12540

tttggagttt gtgaagttcg tgacctcaaa cccaatgggg ccaacatctt ggtaacagag  12600

gagaataaga aggagtatgt acacctggta tgccagatga gaatgacagg agccatccgc  12660

aagcagttgg cggctttctt agaaggcttc tatgagatca ttccaaagcg cctcatttcc  12720

atcttcactg agcaggagtt agagctgctt atatcaggac tgcccaccat tgacatcgat  12780

gatctgaaat ccaacactga ataccacaag taccagtcca actctattca gatccagtgg  12840

ttctggagag cattgcgttc tttcgatcaa gctgaccgtg ccaagttcct ccagtttgtc  12900

acgggtactt ccaaggtacc cctgcaaggc tttgctgccc tcgaaggcat gaatggcatt  12960

cagaagtttc agatccatcg agatgacagg tccacagatc gcctgccttc agctcacaca  13020

tgttttaatc agctggatct gcctgcctat gagagctttg agaagctccg ccacatgcta  13080

ctgttggcta tccaggagtg ctctgaaggc tttgggctgg cctaataagg ccctgcccaa  13140

ctccgtgggg ttttttttac cattgttgga cctggggagg ggggagttaa aaaaagaacc  13200

agaaagaaat tgtcaaaaac caataaatga aatccaccaa ctcaccgtgt gtgtcccagc  13260

tgccccatct tccccagcgc atacctgttc ctcttctcat tctctccccg ccgcctgttt  13320

cctcaccttc tctccccttt ccatgccgtc catgatcccc accccatgtg ttttaaaaag  13380

gcagtagcct ttgcagggac ctgtctgtcc caactgtttg aacagtgtgc tcctcagatt  13440

ctgtgttcag aaggatttgc tgcattgaga cttgaaacct ttggataggg gaaaaaatta  13500

tatatatata tatttttttg ttctgtttgc atttcttaat ttgtgcttgg aatgtgttga  13560

tgtgcacagc taatgattca atgcgagaca agattggcgt ctgtgttgtg gaggtttcaa  13620

ataaagagca ctcttcataa ctcaaaaaaa aaaaaaaaaa aaaaaaaaaa a           13671


<210>  1026
<211>  1419
<212>  DNA
<213>  Homo sapiens

<400>  1026
ctccctccgt ccttgcctcc cttacccacc ctcaccggcc cttgtttctc cttcccctgg     60

gggcagccgc cgccatgatc ctgctggagg tgaacaaccg catcatcgag gagacgctcg    120

cgctcaagtt cgagaacgcg gccgccggaa acaaaccgga agcagtagaa gtaacatttg    180

cagatttcga tggggtcctc tatcatattt caaatcctaa tggagacaaa acaaaagtga    240

tggtcagtat ttctttgaaa ttctacaagg aacttcaggc acatggtgct gatgagttat    300

taaagagggt gtacgggagt ttcttggtaa atccagaatc aggatacaat gtctctttgc    360

tatatgacct tgaaaatctt ccggcatcca aggattccat tgtgcatcaa gctggcatgt    420

tgaagcgaaa ttgttttgcc tctgtctttg aaaaatactt ccaattccaa gaagagggca    480

aggaaggaga gaacagggca gttatccatt atagggatga tgagaccatg tatgttgagt    540

ctaaaaagga cagagtcaca gtagtcttca gcacagtgtt taaggatgac gacgatgtgg    600

tcattggaaa ggtgttcatg caggagttca aagaaggacg cagagccagc cacacagccc    660

cacaggtcct ctttagccac agggaacctc ctctggagct gaaagacaca gacgccgctg    720

tgggtgacaa cattggctac attacctttg tgctgttccc tcgtcacacc aatgccagtg    780

ctcgagacaa caccatcaac ctgatccaca cgttccggga ctacctgcac taccacatca    840

agtgctctaa ggcctatatt cacacacgta tgcgggcgaa aacgtctgac ttcctcaagg    900

tgctgaaccg cgcacgccca gatgccgaga aaaaagaaat gaaaacaatc acggggaaga    960

cgttttcatc ccgctaatct tgggaataag aggaggaagc ggctggcaac tgaaggctgg   1020

aacacttgct actggataat cgtagctttt aatgttgcgc ctcttcaggt tcttaaggga   1080

ttctccgttt tggttccatt ttgtacacgt ttggaaaata atctgcagaa acgagctgtg   1140

cttgcaaaga cttcatagtt cccaagaatt aaaaaaaaaa aaaaaagaat tccacttgat   1200

caacttaatt ccttttcttt atcttccctc cctcacttcc cttttctccc accctctttt   1260

ccaagctgtt tcgctttgca atatattact ggtaatgagt tgcaggataa tgcagtcata   1320

acttgttttc tcctaagtat ttgagttcaa aactcctgta tctaaagaaa tacggttggg   1380

gtcattaata aagaaaatct ttctatctta aaaaaaaaa                          1419


<210>  1027
<211>  3758
<212>  DNA
<213>  Homo sapiens

<400>  1027
aagagtctgc gggaccggca gctgtacttc atctcccagc gggccgagcg ctgaaggcag     60

cggcgcggcg cctttgtggt agcagtggcc ccgcgcggag gaagttccgg tgtccgcggc    120

gctgggtcgg tggcggaggc tgaggagaag gaggagcggg ccgtggaggc ttcgccgcct    180

aggtactgct ataaccagaa tttggtagaa aaaggattta cttgttgggg ccctcttgat    240

aaaaagagat gtggggggat tctcgacctg ctaacagaac tggacctttt cgtgggagcc    300

aagaagaaag gtttgctccc gggtggaaca gggattatcc tcctcctccc cttaagagtc    360

atgctcaaga gagacactct ggcaactttc ctggcagaga ttcacttccc tttgatttcc    420

aggggcattc ggggcctcct tttgcaaatg tagaggagca ttctttcagc tatggagcta    480

gagacggacc gcatggtgac tatcgaggag gggagggacc tggacatgat ttcagggggg    540

gagatttttc gtcttctgat ttccagagca gagattcatc acagttggac ttcaggggta    600

gggacataca ttctggggat tttcgggata gagaaggacc acctatggac tataggggtg    660

gagatggtac ttctatggat tatagaggta gggaggcacc tcatatgaac tacagagaca    720

gggatgctca cgctgttgac ttcagaggta gggatgctcc tccatctgac ttcaggggcc    780

ggggcactta tgatttagat tttagaggcc gggatggatc ccatgcagat tttaggggaa    840

gggatttatc agatttggat tttagggcca gagaacagtc ccgttctgat tttaggaata    900

gagatgtatc tgatttggac tttagagaca aagacggaac acaagtagac tttagaggcc    960

gaggttcagg tactactgat ctagacttta gggacaggga tacgccacat tcagatttca   1020

gaggtagaca ccgatctagg actgatcagg attttagggg cagagagatg ggatcttgta   1080

tggaatttaa agatagggag atgccccctg tggatccaaa tattttggat tacattcagc   1140

cctctacaca agatagagaa cattctggta tgaatgtgaa caggagagaa gaatccacac   1200

atgaccatac gatagaaagg cctgcttttg gcattcagaa gggagaattt gagcattcag   1260

aaacaagaga aggagaaaca caaggtgtag cctttgaaca tgagtctcca gcagactttc   1320

agaacagcca aagtccagtt caagaccaag ataagtcaca gctttctgga cgtgaagagc   1380

agagttcaga tgctggtctg tttaaagaag aaggcggtct ggactttctt gggcggcaag   1440

acaccgatta cagaagcatg gagtaccgtg atgtggatca taggctgcca ggaagccaga   1500

tgtttggcta tggccagagc aagtcttttc cagagggcaa aactgcccga gatgcccaac   1560

gggaccttca ggatcaagat tataggaccg gcccaagtga ggagaaaccc agcaggctta   1620

ttcgattaag tggggtacct gaagatgcca caaaagaaga gattcttaat gcttttcgga   1680

ctcctgatgg catgcctgta aagaacttgc agttgaagga gtataacaca ggttacgact   1740

atggctatgt ctgcgtggag ttttcactct tggaagatgc catcggatgc atggaggcca   1800

accagggaac tctaatgatc caggacaaag aagttaccct ggagtatgta tcaagcctgg   1860

atttttggta ctgcaaacga tgtaaggcaa acattggtgg gcaccgatct tcctgttcat   1920

tctgcaagaa cccaagagaa gtgacagagg ccaagcaaga attaataacc taccctcagc   1980

ctcagaaaac atccatacca gcaccattgg aaaaacagcc caaccagccc ctaagaccag   2040

ctgataagga acctgaaccc aggaagaggg aagaaggcca agagtcacgc ttaggacatc   2100

aaaagagaga agcagaaagg tatctgcctc cttctcgaag ggaagggcca actttccgaa   2160

gagaccgaga gagggagtca tggtctggag agacacgcca ggatggagag agcaaaacta   2220

tcatgctaaa gcgtatctat cgttccacac cacctgaggt gatagtggaa gtgctggagc   2280

cctatgtccg ccttactact gccaacgtcc gtatcatcaa gaacagaaca ggccctatgg   2340

ggcataccta tggctttatt gacctcgact cccatgcgga agctcttcgt gtggtgaaga   2400

tcttacagaa ccttgatccg ccatttagca ttgatgggaa gatggtagct gtaaacctgg   2460

ccactggaaa acgaagaaat gattctgggg accattctga ccacatgcat tactatcagg   2520

gtaaaaaata tttccgagat aggaggggag gtggcagaaa ttcagactgg tcttcagata   2580

caaatcgaca aggacaacag tcatcatctg actgctacat atatgattct gctactggct   2640

actattatga ccccttggca ggaacttatt atgaccccaa tacccagcaa gaagtctatg   2700

tgccccagga tcctggatta cctgaggaag aagagatcaa ggaaaaaaaa cccaccagtc   2760

aaggaaagtc aagtagcaag aaggaaatgt ctaaaagaga tggcaaggag aaaaaagaca   2820

gaggagtgac gaggtttcag gaaaatgcca gtgaagggaa ggcccctgca gaagacgtct   2880

ttaagaagcc cctgcctcct actgtgaaga aggaagagag tccccctcca cctaaagtgg   2940

taaacccact gatcggcctc ttgggtgaat atggaggaga cagtgactat gaggaggaag   3000

aagaggagga acagacccct cccccacagc cccgcacagc acagccccag aagcgagagg   3060

agcaaaccaa gaaggagaat gaagaagaca aactcactga ctggaataaa ctggcttgtc   3120

tgctttgcag aaggcagttt cccaataaag aagttctgat caaacaccag cagctgtcag   3180

acctgcacaa gcaaaacctg gaaatccacc ggaagataaa acagtctgag caggagctag   3240

cctatctgga aaggagagaa cgagagggaa agtttaaagg aagaggaaat gatcgcaggg   3300

aaaagctcca gtcttttgac tctccagaaa ggaaacggat taagtactcc agggaaactg   3360

acagtgatcg taaacttgtt gataaagaag atatcgacac tagcagcaaa ggaggctgtg   3420

tccaacaggc tactggctgg aggaaaggga caggcctggg atatggccat cctggattgg   3480

cttcatcaga ggaggctgaa ggccggatga ggggccccag tgttggagcc tcaggaagaa   3540

ccagcaaaag acagtccaac gagacttacc gagatgctgt tcgaagagtc atgtttgctc   3600

gatataaaga actcgattaa gaaaggagac aagttccatg ggatacaacc tccctcttgt   3660

tttgtttgtc tctccttttc ttttgttact gttcttgctg ctagaacttt tttaaataaa   3720

ctttttttca atgtgattaa aaaaaaaaaa aaaaaaaa                           3758


<210>  1028
<211>  1650
<212>  DNA
<213>  Homo sapiens

<400>  1028
acaggctgtt gcgggagcgc gccctcagcg aagcaagtga ggcatctcac tgggaaagtc     60

gaatgtgtgt ggcggccgcc gccgaggcgg gttccgaaga gacctcagca gggcaggcca    120

gggcctacgc gaacgcccac ccttaagagc gcggggacag ggaactggag cgttcctccc    180

agcccccgac gtcgcgggcc cagtgtcccc gtccaggctg gttgggcgca cgcgcggccc    240

cactcgcccc cacgcgtgcg tccccgctgg tcccgccccc ggccggaagt tccggcggcg    300

gagctgggcc gggcccgagc ggatcgcggg ctcgggctgc ggggctccgg ctgcgggcgc    360

tgggccgcga ggcgcggagc ttgggagcgg agcccaggcc gtgccgcgcg gcgccatgaa    420

gggcaaggag gagaaggagg gcggcgcacg gctgggcgct ggcggcggaa gccccgagaa    480

gagcccgagc gcgcaggagc tcaaggagca gggcaatcgt ctgttcgtgg gccgaaagta    540

cccggaggcg gcggcctgct acggccgcgc gatcacccgg aacccgctgg tggccgtgta    600

ttacaccaac cgggccttgt gctacctgaa gatgcagcag cacgagcagg ccctggccga    660

ctgccggcgc gccctggagc tggacgggca gtctgtgaag gcgcacttct tcctggggca    720

gtgccagctg gagatggaga gctatgatga ggccatcgcc aatctgcagc gagcttacag    780

cctggccaag gagcagcggc tgaacttcgg ggacgacatc cccagcgctc ttcgaatcgc    840

gaagaagaag cgctggaaca gcattgagga gcggcgcatc caccaggaga gcgagctgca    900

ctcctacctc tccaggctca ttgccgcgga gcgtgagagg gagctggaag agtgccagcg    960

aaaccacgag ggtgatgagg acgacagcca cgtccgggcc cagcaggcct gcattgaggc   1020

caagcacgac aagtacatgg cggacatgga cgagcttttt tctcaggtgg atgagaagag   1080

gaagaagcga gacatccccg actacctgtg tggcaagatc agctttgagc tgatgcggga   1140

gccgtgcatc acgcccagtg gcatcaccta cgaccgcaag gacatcgagg agcacctgca   1200

gcgtgtgggt cattttgacc ccgtgacccg gagccccctg acccaggaac agctcatccc   1260

caacttggct atgaaggagg ttattgacgc attcatctct gagaatggct gggtggagga   1320

ctactgaggt tccctgccct acctggcgtc ctggtccagg ggagccctgg gcagaagccc   1380

ccggccccta tacatagttt atgttcctgg ccaccccgac cgcttccccc aagttctgct   1440

gttggactct ggactgtttc ccctctcagc atcgcttttg ctgggccgtg atcgtccccc   1500

tttgtgggct ggaaaagcag gtgagggtgg gctgggctga ggccattgcc gccactatct   1560

gtgtaataaa atccgtgagc acgaggtggg acgtgctggt gtgtgaaaaa aaaaaaaaaa   1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa                                    1650


<210>  1029
<211>  5415
<212>  DNA
<213>  Homo sapiens

<400>  1029
attggctagg ccagggcgcc tgcgcggcgg ggttctcggt cgccagccat tcctgaggag     60

gactgccggt cgttcggacg tcttgcctgt cgctggagga gaggtccggg ctctccagga    120

aggtggctgc ggcgacaaaa tgaagatatt cgtgggcaac gtcgacgggg cggatacgac    180

tccggaggag ctggcagccc tctttgcgcc ctacggcacg gtcatgagct gcgccgtcat    240

gaaacagttc gccttcgtgc acatgcgcga gaacgcgggc gcgctgcgcg ccatcgaagc    300

cctgcacggc cacgagctgc ggccggggcg cgcgctcgtg gtggagatgt cgcgcccaag    360

gcctcttaat acttggaaga ttttcgtggg caatgtgtcg gctgcatgca cgagccagga    420

actgcgcagc ctcttcgagc gccgcggacg cgtcatcgag tgtgacgtgg tgaaagacta    480

cgcgtttgtt cacatggaga aggaagcaga tgccaaagcc gcaatcgcgc agctcaacgg    540

caaagaagtg aagggcaagc gcatcaacgt ggaactctcc accaagggtc agaagaaggg    600

gcctggcctg gctgtccagt ctggggacaa gaccaagaaa ccaggggctg gggatacggc    660

cttccctgga actggtggct tctctgccac cttcgactac cagcaggctt ttggcaacag    720

cactggtggc tttgatgggc aagcccgtca gcccacacca cccttctttg gtcgcgaccg    780

cagccctctg cgccgttcac ctccccgagc ctcttatgtg gctcctctga cggcccagcc    840

agctacctac cgggcccagc cgtccgtgtc actgggagct gcctacaggg cccagccttc    900

tgcctctttg ggtgttggct atcggactca gcccatgaca gcccaggcag cctcttaccg    960

cgctcagccc tctgtctccc ttggggcacc atacaggggc cagctggcta gtcctagctc   1020

ccagtctgct gcagcttctt cactcggccc atatggtgga gcccagccct cagcctcggc   1080

cctttcctcc tatgggggtc aggcagctgc agcttcttcg ctcaactcct atggggctca   1140

gggttcctcc cttgcctcct atggtaacca gccatcctct tacggcgccc aggctgcctc   1200

ttcctatggg gttcgtgcag ctgcttcttc ctacaacacc cagggagcag cttcctcctt   1260

aggctcctac ggggctcagg cagcctccta tggggcccag tctgcagcct cctcactagc   1320

ttatggagcc caggcagctt catataatgc ccagccctcg gcctcttaca atgcccagtc   1380

tgccccatat gctgcacagc aggctgcttc ctactcttcc caacctgctg cctatgtggc   1440

acagccagcc acagctgctg cctatgccag ccagccagca gcctacgccg cacaagccac   1500

taccccaatg gctggctcct atggggccca gccggttgtg cagacccagc tgaatagtta   1560

cggggcccaa gcatcaatgg gcctttcagg ctcctatggg gctcagtcgg ctgctgcggc   1620

cactggctcc tatggtgccg cagcagccta cggggcccaa ccttctgcca ccctggcagc   1680

tccttaccgc actcagtcat cagcctcatt ggctgcttcc tatgctgccc agcagcatcc   1740

ccaggctgct gcctcctacc gcggccagcc aggcaatgcc tacgatgggg caggtcagcc   1800

gtctgcagcc tacctgtcca tgtcccaggg ggccgttgcc aacgccaaca gcaccccgcc   1860

gccctatgag cgtacccgcc tctccccacc ccgggccagc tacgacgatc cctacaaaaa   1920

ggctgtcgcc atgtcgaaaa ggtatggttc cgaccggcgt ttagccgagc tctctgatta   1980

ccgccgttta tcagagtcgc agctttcgtt ccgccgctcg ccgacaaagt cctcgctgga   2040

ttaccgtcgc ctgcccgatg cccattccga ttacgcacgc tattcgggct cctataatga   2100

ttacctgcgg gcggctcaga tgcactctgg ctaccagcgc cgcatgtagg gccatcctgg   2160

gatggggcac cacagggagg gagggagaaa agaggtgggt agggttacag atccaggtta   2220

taactactct ggcccatacc tttcctggtt gtggtttttc atgccctcta ccatgtgggc   2280

cttccccagg agatgatcct gttaagtgtt cggcagtaac ctactttgtt ccttcgcctc   2340

agcagcaaat cttgctactg gctctagatc tgcggtttcc cctctaccct gcctcccgtc   2400

tccccagaat gggaatttct tttatgtttt tatttttttc ctggctccct tttatttttg   2460

tgcgcgatat ttaaggtcgt ctggatgggg aagcaacctg cagctgaggt cgccggcgcc   2520

tttttctttt tagatgggaa ggaggccagg aaagggtcag cttaaccatt tcctatgtgc   2580

caagctgtgc cagcagtcca gggtaccctg actgtccctc tgtagactgt tgagactgag   2640

ttcctgttgg gacagtcagt tggtatgtat ccaagtccct gctgaccact aatgttctag   2700

ctgatggtga gcggcacagt cccacttccc catctcccca agtaggtggt gttagaaaac   2760

cttaattttt tttccctttt gtatggacta caaataaaac ttggggcaat ttgcagtttg   2820

gaaacctggt tgtcattgtc ttgattgcat tcagtgtcaa aggagccaat ttgacatcca   2880

ggaagacatg atagctaaag ggaaggcagt cagagaaccc aggactggtg aggaaagggg   2940

tttgaatgtc ggaattagaa ggattgccct gtggcccaga aggatttagc tcatcgtcgt   3000

cctgctagcc tgccatcttt cagactttcc agggcaggtg gcctggtcct cagccctcaa   3060

cttgagttag tcacaccaaa atgcagtaaa tgatgcccat tttcctctgc ctgtgcttga   3120

ccattttcac tgacttttct ccagttcagg aataacctgt gttccaatgg gatggttctg   3180

gggtttggcc tcttaggaag tggggaatgg gctgctgtgg tatttacagg ctagtagatc   3240

ctttaggcag taggctggaa tgagtgctgg ggctgggacc cagaaaggaa ccagtagtgg   3300

agtgggggta atggcgttgc ctgatactgc cctatggttg gaataaggaa gggcagagaa   3360

aacttgaagc aggtatgggg cattctggcc atagagctcg tattttgcct gttgagctgt   3420

accatggagc atcctcctgt gtcctgccaa cccctgccat tatagtcacc ggagactcct   3480

ttacctatcc ctatctgtta gggttttcag atgtcctctc gctgggttta tatttgaagg   3540

tatagaatct gggaaagggt ggggtgcaag ctaaccaaat agggatgcta gggttgggtg   3600

gggaattgag gactcttctg tgcttttatt gtagggctgg ggatcgagga tctgggcaaa   3660

aaatatgaca tttccaacca gggacaaaat ggaggcttgg gcttagtgat gggtaaatgg   3720

aagactggtt gagtgggatg ataatgggag aacttactga tgctcttttg ggaaaaggtg   3780

ctttaaagac tcgatttggg agcctactgg ggcaaggcga ctggggaggt gtacgtgtta   3840

gtcaagtgga ggtcaggtgg gttatcttct gcctccttca ctggcttcat gtgaacttgc   3900

ctgtgacaga atatcttgcc ctagatgtcc tcttccctct tgccatcgtg caaaagcatt   3960

cgatcttatg accgtgagtt cttatttgtg gatgctaact ggggtaatct cagggagtac   4020

tggggccatg gctctttccc ttgcttctct ttctgctcac tgctttgctt tcaggtgctt   4080

agctgctcct ttttatttct ttgcaggact gggaaagcat gggaggagga ttttgataag   4140

tttcttgttc tctgcgtggt gatggggtgg tctgagggcc aagttaataa gcctaccttt   4200

ggttattacc ctggaaaatt gagggttgat ggtagggtta tgattgtggc ctgtgtattt   4260

gcaatttttc tttgtcagtg tggctttctg tcatcttcct ttttctccag tgagggttct   4320

gccactgtct caatcccttg gttcctgcaa aaaacagcta aatgtgctct cagggccagt   4380

ggtgatgttc tgtgttgcag ccccagctct tgaaagtgac ctggcccaga tgagctctgc   4440

ctgcttgtca tctttaggtc ctgctgcccc tgctgcctca gccctcaggc tcctaactgc   4500

tcaagccaga aggagctaca aagccaaatc atttgtcatt tttctctggc agattgtttt   4560

aaaatctccc tcccctcttt tattttaatt atgccacctg tgttaatcct atagcctgct   4620

tctttgcttt gtggattact gatttcaagt tctataactt ggggaaagtt aggttgagtg   4680

aatgggagga cagacactga atgtgtgttt tggaaaaatg gactctctat cttcagatta   4740

ttcagcttct ccacctatca cctctacaac ttggccttca ttggagaagt tttagttggc   4800

ttattcctgg aacaagacca cctagaggct tttagccttg tcagcctgcc ctcttctgag   4860

gtttggacct tgttttaaat tgtgtgcatg gtgggcttga gactctcttg taatggaggt   4920

aatgggacta tcactgaggg gttcagccta tccaggtagg ctaccgttct agtcataccc   4980

atcacttaaa ttctgccaca gtctgcacag acggttggtc ctccaggcat attgtcctat   5040

taagccaaat aggtggacat catgggatgg atgaggtcat catgaaaaca gatttactgg   5100

atttatggac ctagtatata ctatgtaaca gatggaaaac tgaattttac aatctatagg   5160

tacctttgaa aggtcataaa gggtaaaagt ctatagtttt ccagaaaata attcttaaaa   5220

ctgggtttta tgtctagatt taaatcatgt atctgtctgt agtgcttcaa atgtggccag   5280

gtgtggtagc tcacacctgt aattcccagc gctttgggaa tttgaggcaa gaggattgct   5340

agaggccagg attttgagac cagcttcggc aatacggtga gaccttgtct ctaccaaaag   5400

aaaagaaaaa aaaaa                                                    5415


<210>  1030
<211>  1343
<212>  DNA
<213>  Homo sapiens

<400>  1030
acatccggcc gccggcactg gattgcttct gtctggcggc ggcagcatgg cggcgggggc     60

ggctgaggca gctgtagcgg ccgtggagga ggtcggctca gccgggcagt ttgaggagct    120

gctgcgcctc aaagccaagt ccctccttgt ggtccatttc tgggcaccat gggctccaca    180

gtgtgcacag atgaacgaag ttatggcaga gttagctaaa gaactccctc aagtttcatt    240

tgtgaagttg gaagctgaag gtgttcctga agtatctgaa aaatatgaaa ttagctctgt    300

tcccactttt ctgtttttca agaattctca gaaaatcgac cgattagatg gtgcacatgc    360

cccagagttg accaaaaaag ttcagcgaca tgcatctagt ggctccttcc tacccagcgc    420

taatgaacat cttaaagaag atctcaacct tcgcttgaag aaattgactc atgctgcccc    480

ctgcatgctg tttatgaaag gaactcctca agaaccacgc tgtggtttca gcaagcagat    540

ggtggaaatt cttcacaaac ataatattca gtttagcagt tttgatatct tctcagatga    600

agaggttcga cagggactca aagcctattc cagttggcct acctatcctc agctctatgt    660

ttctggagag ctcataggag gacttgatat aattaaggag ctagaagcat ctgaagaact    720

agatacaatt tgtcccaaag ctcccaaatt agaggaaagg ctcaaagtgc tgacaaataa    780

agcttctgtg atgctcttta tgaaaggaaa caaacaggaa gcaaaatgtg gattcagcaa    840

acaaattctg gaaatactaa atagtactgg tgttgaatat gaaacattcg atatattgga    900

ggatgaagaa gttcggcaag gattaaaagc ttactcaaat tggccaacat accctcagct    960

gtatgtgaaa ggggagctgg tgggaggatt ggatattgtg aaggaactga aagaaaatgg   1020

tgaattgctg cctatactga gaggagaaaa ttaataaatc ttaaacttgg tgcccaacta   1080

ttgtaagaaa tatttaatta cattgggagc agttcatgat ttagtcctca gaaatggact   1140

aggaatagaa aattcctgct ttctcagtta catgttttgt gtatttcaca atgtcgtgct   1200

aaataaatgt atgttacatt tttttcccac caaaaataga atgcaataaa catcttcaaa   1260

ttattaacaa taattgtatg aaaaaagtgt atctttacag cagtattaaa catacagcta   1320

ctataattaa aaaaaaaaaa aaa                                           1343


<210>  1031
<211>  2142
<212>  DNA
<213>  Homo sapiens

<400>  1031
atggcgaagt ccccggagaa ctctaccctg gaggagattc tggggcagta tcaacggagt     60

ctccgggaac atgccagcag aagcattcac caactgacat gtgccctgaa agaaggcgat    120

gtcactattg gagaagatgc accaaatctt tcttttagca ccagtgtggg aaatgaggac    180

gccaggacag cctggcccga attacaacag agccatgctg ttaatcagct caaagatttg    240

ttgcgccaac aagcagataa ggaaagtgaa gtatctccgt caagaagaag aaaaatgtcc    300

cccttgaggt cattagaaca tgaggaaacc aatatgccta ctatgcacga ccttgttcat    360

actattaatg accagtctca atatattcat catttagagg cagaagttaa gttctgcaag    420

gaggaactct ctggaatgaa aaataaaata caagtagttg tgcttgaaaa cgaagggctc    480

cagcaacagc taaaatctca aagacaagag gagacactga gggaacaaac acttctggat    540

gcatccggaa acatgcacaa ttcttggatt acaacaggtg aagattctgg ggtgggcgaa    600

acctccaaaa gaccattttc ccatgacaat gcagattttg gcaaagctgc atctgctggt    660

gagcagctag aactggagaa gctaaaactt acttatgagg aaaagtgtga aattgaggaa    720

tcccaattga agtttttgag gaacgactta gctgaatatc agagaacttg tgaagatctt    780

aaagagcaac taaagcataa agaatttctt ctggctgcta atacttgtaa ccgtgttggt    840

ggtctttgtt tgaaatgtgc tcagcatgaa gctgttcttt cccaaaccca tactaatgtt    900

catatgcaga ccatcgaaag actggttaaa gaaagagatg acttgatgtc tgcactagtt    960

tccgtaagga gcagcttggc agatacgcag caaagagaag caagtgctta tgaacaggtg   1020

aaacaagttt tgcaaatatc tgaggaagcc aattttgaaa aaaccaaggc tttaatccag   1080

tgtgaccagt tgaggaagga gctggagagg caggcggagc gacttgaaaa agaacttgca   1140

tctcagcaag agaaaagggc cattgagaaa gacatgatga aaaaggaaat aacgaaagaa   1200

agggagtaca tgggatcaaa gatgttgatc ttgtctcaga atattgccca actggaggcc   1260

caggtggaaa aggttacaaa ggaaaagatt tcagctatta atcaactgga ggaaattcaa   1320

agccagctgg cttctcggga aatggatgtc acaaaggtgt gtggagaaat gcgctatcag   1380

ctgaataaaa ccaacatgga gaaggatgag gcagaaaagg agcacagaga gttcagagca   1440

aaaactaaca gggatcttga aattaaagat caggaaatag agaaattgag aatagaactg   1500

gatgaaagca aacaacactt ggaacaggag cagcagaagg cagccctggc cagagaggag   1560

tgcctgagac taacagaact gctgggcgaa tctgagcacc aactgcacct caccagacag   1620

gaaaaagata gcattcagca gagctttagc aaggaagcaa aggcccaagc ccttcaggcc   1680

cagcaaagag agcaggagct gacacagaag atacagcaaa tggaagccca gcatgacaaa   1740

actgaaaatg aacagtattt gttgctgacc tcccagaata catttttgac aaagttaaag   1800

gaagaatgct gtacattagc caagaaactg gaacaaatct ctcaaaaaac cagatctgaa   1860

atagctcaac tcagtcaaga aaaaaggtat acatatgata aattgggaaa gttacagaga   1920

agaaatgaag aattggagga acagtgtgtc cagcatggga gagtacatga gacgatgaag   1980

caaaggctaa ggcagctgga taagcacagc caggccacag cccagcagct ggtgcagctc   2040

ctcagcaagc agaaccagct tctcctggag aggcagagcc tgtcggaaga ggtggaccgg   2100

ctgcggaccc agttacccag catgccacaa tctgattgct ga                      2142


<210>  1032
<211>  4225
<212>  DNA
<213>  Homo sapiens

<400>  1032
gcagagggtg cggcccagag gaggccgcgg gccgggaagg gccgggcggg acgggaaacg     60

ttagggcagc ggcccccggg gtgagggggc cgagcggacg ggcagggccc cgaggcgaac    120

tctgcccgga tgaggaacaa agcagtgggg caggcgcgtg cgcccccagc gcagctggca    180

ggttgggcag cccccttccc gaagcttctg gacggaaggc cccaggtgtt ccccgagatg    240

ccccaacccg tggcggggtg cacggccacc ggccctcggg agaagttggg cggccccggg    300

cgaccccggg gacgagtggc cgcgtcggtg cagcggttgt gagcaagatg tggtagcacg    360

tgaccctgga acgcaaaccc tgatgcctgt tccccaccac ccgagcgctc ctttctctga    420

tatttggccc caagccgatg catcacagga tgaatgaaat gaacctgagt ccagtgggga    480

tggagcagct gacttcatcc tctgtgagca atgccttgcc agtctcagga agtcacctgg    540

gattggctgc ctcacccact cacagtgcca tccctgcccc aggcctccca gtggcaattc    600

caaacctggg tccctccctg agctctctgc cttctgctct gtctttaatg ctaccaatgg    660

gtattgggga tcgaggggtg atgtgtgggt tacctgaaag aaactacacc ctacctccac    720

caccttaccc tcacctggag agcagttatt tcagaaccat tctacctggc attttatctt    780

atttagctga cagaccacct ccacagtaca tccaccctaa ctctataaat gttgatggta    840

atacagcatt atctatcacc aataaccctt cagcactaga tccctatcag tccaatggaa    900

atgttggatt agaaccaggc attgtttcaa tagactctcg ctctgtgaac acacatggtg    960

cccaaagtct tcatcccagt gatggccatg aggtggcctt ggacacagca atcactatgg   1020

agaacgtttc tagggttacc agcccaattt cgacagatgg aatggcagag gagcttacga   1080

tggacggtgt tgcaggcgag cattcccaaa tcccaaatgg ctccagaagt catgaacctc   1140

tgtctgtgga ttctgtgagc aacaaccttg cagcagacgc tgtaggacat ggtggtgtga   1200

tacccatgca tgggaatggc ctggagctcc ctgtggtcat ggagacagac cacattgcaa   1260

gtcgggtcaa tggcatgtct gacagtgccc tcagtgactc cattcacact gtggccatga   1320

gcaccaactc tgtaagcgtg gcactctcta cctcacacaa ccttgcctcc ctagaatctg   1380

tttccctcca tgaagttggc ctcagcctag aacctgtggc tgtctcctcc atcacccagg   1440

aggttgctat ggggacaggt catgtagatg tatcttcaga cagtctttct tttgtatcac   1500

cttcactgca aatggaagac tccaattcaa acaaggagaa catggcaacc ttgtttacaa   1560

tttggtgtac tctgtgtgac cgcgcctatc cctcggactg tcccgaacat ggaccagtga   1620

cttttgttcc tgacactcca atagagagca gagcaaggct ttctctccca aagcagcttg   1680

ttctccgtca gtcaattgtg ggagcagaag ttggtgtatg gactggagaa accattcctg   1740

tgcggacttg ctttggacct ctaattggcc agcagagtca ctccatggaa gtagcagaat   1800

ggacagacaa ggcagttaac catatctgga agatatacca caatggtgtc ctagaattct   1860

gcatcattac aactgatgaa aatgaatgta attggatgat gtttgtgcgc aaagccagga   1920

accgggaaga gcagaatttg gtggcttatc ctcatgatgg aaaaatcttt ttctgcacct   1980

cacaagatat ccctcctgaa aatgaactgc ttttttatta tagccgagat tatgctcaac   2040

agattggtgt tcctgaacac ccagatgtgc atctctgtaa ctgtggcaag gagtgcaatt   2100

cttacacaga gttcaaagcc catctgacca gccacatcca taaccatctt cctacccagg   2160

gacatagcgg cagccatggg ccaagtcaca gcaaagaaag gaagtggaag tgctcaatgt   2220

gcccccaagc ttttatctct ccttccaaac ttcatgtcca ctttatgggt cacatgggta   2280

tgaagcccca caagtgtgat ttctgtagca aggcttttag tgatcccagc aacctgcgga   2340

cccacctcaa gatacataca ggtcagaaga actacaggtg taccttgtgt gacaagtctt   2400

tcacccagaa ggctcacctg gagtcccaca tggttatcca cactggggag aagaatctta   2460

agtgtgatta ctgtgacaag ttgtttatgc ggaggcagga cctcaagcag cacgtgctca   2520

tccacactca agaacgccag atcaagtgtc ccaagtgtga taagctgttc ttgagaacaa   2580

atcacttaaa gaagcatctc aattctcatg aaggaaaacg ggattatgtc tgtgaaaaat   2640

gtacaaaggc ttatctaacc aaataccatc tcacccgcca cctgaaaacc tgcaaagggc   2700

ccacctccag ttcgtcagca ccagaggagg aagaagagga tgactcagaa gaggaagatc   2760

tagcagactc tgtggggaca gaagactgta ggattaacag tgctgtgtat tcagcggatg   2820

agtctctttc tgcacataaa taaaaggaaa agaaacaagc aattttggat gaaaatgcaa   2880

atggaaaaat acacataacc agttatctac tataatggtt tttatataaa atggttcctg   2940

atttattttc agccagtaat caaaacagac tgggaatgaa taaagcactt acagaagagt   3000

atcctaatga aaacacttta aaacagattg ggaaaactga gcatgtgtcc tgttttaagt   3060

ggtggactgg gagggaagtg tcaacttctg aggtctttat ttacatgata atctgggaga   3120

tgcatttatg cctgaatcaa agctgccttc tgctcaaaca aatcagattt atttcacatt   3180

cttccattat tccattttcc tgctggtcct gtgacttggt aacattctaa acggtccttg   3240

ccccatagcc atcctgattg ctgatagtgt tttatgcaga ctcttgtgac ttatactcac   3300

cacagaatgg attgggacac agcagcataa gtgtgctact tggcagctag taagtttaaa   3360

gcaggacctg ccttaactgc tcctggccac ttggaagttt agggtagatc ttgttttcca   3420

aagtttcggc aggtgcctgg agggcaaata aaaaagcagc agtcagtcag tagtcagtga   3480

tggagagaac aagaggagag atgcctggcc tctgcccaag aaattagctt tgatggaagc   3540

ctgagcaagt cacctggtta ttgtaacgtg gagatctttg taggtttaga catggctccc   3600

tgtctccagt aaacatccag ccattcagac aaagggggcc tggagataca gagagcccaa   3660

ataatgcctg ctggattgtc tcctgatgag tacatgtgga ctcacctgag gaagggaagg   3720

aagggaataa tcttttatgt ttcatttacc ttatgaaaag tgttaaaaca ttgccaactc   3780

aaaataacat tatttaatgc atgtgcaaag ttaggtcttc ccagttgtct cagtgctgag   3840

gaacctcatc agagaagcat ggaagatgcc aaaggatttt tggaaggtaa agaaggctga   3900

atagtgacca catgggcctg ttttcagggt cccagcttag ttaagtcacc catgcacctg   3960

gtcattgtgt ctcccatgca catccagcgt ttctcagaag cagacccacc cttaagttga   4020

caggattgat ggaacatgct ctcctgctca aggcacaacc tctgggctgg agtagaggac   4080

tctggtggga aggttttgct gctaatgtat ttatggaatg aatgtatttc attcaaatct   4140

gtattcctct aggaaggatt aaaattaaac ttttttaaaa tacaggaaaa aaaaaaaaaa   4200

aaaaaaaaaa aaaaaaaaaa aaaaa                                         4225


<210>  1033
<211>  5820
<212>  DNA
<213>  Homo sapiens

<400>  1033
cgtttagtca catcaagaaa tagaacagaa ttcagccatg gccccaagaa agagaggtgg     60

acgaggtatt tcattcatct tttgctgttt ccgaaataat gatcacccag aaatcacgta    120

tcggctgcga aatgatagca actttgcgct tcagaccatg gaaccagcat tgcccatgcc    180

ccctgtggag gagctggatg tcatgttcag tgaactggtg gatgaactgg acctcacaga    240

caaacacaga gaagccatgt ttgcacttcc agctgagaaa aaatggcaaa tatactgtag    300

caagaaaaag gaccaggaag aaaacaaggg agctacaagt tggcctgaat tctacattga    360

tcagctcaat tccatggctg ctagaaaatc tctgctggct ttagagaagg aagaagaaga    420

agaaagaagt aaaactatag agagtttaaa gacagcactg aggacaaaac caatgaggtt    480

tgtaaccaga ttcatcgact tggatggcct atcatgtatc ctcaactttc taaagaccat    540

ggactacgag acctcagagt ctcgaataca tacttctctc attggctgta taaaggcgtt    600

aatgaacaac tctcaaggcc gggctcacgt cctggctcat tctgagagta ttaatgtaat    660

tgctcagagt ctgagcacag agaacattaa aacgaaggtg gccgtgctgg aaatcttggg    720

cgccgtgtgc ctggttcccg ggggccacaa gaaggttctg caggccatgc tgcactacca    780

gaagtatgcc agcgaaagga cccgctttca gacattaatt aacgacttgg ataaaagcac    840

tgggcggtat cgagatgaag tgagtctcaa gactgccatc atgtccttca ttaatgcagt    900

gctcagccaa ggtgcaggag tggagagttt ggactttaga cttcatcttc gctatgaatt    960

tctgatgtta ggaattcaac ctgtaataga taaattaagg gaacacgaaa attcaacatt   1020

agataggcat ttagactttt ttgaaatgct ccgaaatgaa gatgaactag aatttgccaa   1080

aagatttgaa ctggttcaca tagacacaaa aagtgcaact cagatgtttg agctgaccag   1140

gaagaggctg acacatagtg aagcttaccc gcatttcatg tccatcctgc accactgcct   1200

ccaaatgcct tacaagagga gtggcaacac tgttcagtac tggctactac tagatagaat   1260

tatacagcag atagttatcc agaatgacaa aggacaggac cctgactcca cacctttgga   1320

aaactttaat attaagaatg tcgtacgaat gttggttaat gaaaatgaag ttaagcagtg   1380

gaaagaacaa gcggaaaaaa tgagaaaaga gcacaatgag ctacaacaga aactggaaaa   1440

gaaagaacga gaatgtgatg ctaagactca agagaaggaa gagatgatgc agaccttaaa   1500

taaaatgaaa gagaaacttg aaaaggagac tactgagcat aagcaagtca agcagcaggt   1560

ggcggacctc acagcacagc tccatgagct cagcaggagg gccgtctgtg cttcaatccc   1620

aggtggaccc tcgcctggag caccaggagg gccctttcct tcctctgtgc ctggatctct   1680

ccttcctccc ccaccacccc cacctctacc aggtgggatg cttccccctc caccgcctcc   1740

cctccctcca ggtggccctc ctcctccccc agggcctcct cccttagggg caatcatgcc   1800

acctcctggt gctccaatgg gcctagcact gaagaagaaa agcattcctc agcccacaaa   1860

tgccctgaaa tccttcaact ggtctaaact gcccgagaac aaactggaag gaacagtatg   1920

gaccgaaatt gatgatacaa aagtcttcaa aattctagat cttgaagacc tggaaagaac   1980

cttctctgcc tatcaaagac agcaggattt ctttgtgaac agtaactcca agcagaaaga   2040

agcagatgcc attgatgaca ctctgagttc caaacttaaa gttaaagagc tttcggtgat   2100

tgatggtcgg agagctcaga attgcaacat ccttctatcg aggttgaaat tatccaatga   2160

cgaaatcaaa cgggcaattc taacaatgga cgaacaggaa gatctgccca aggacatgtt   2220

ggaacagctc ttgaaatttg ttcctgaaaa aagtgacatt gacctattgg aggaacataa   2280

acacgaactg gatcggatgg ccaaggctga taggttcctt tttgagatga gccgaattaa   2340

tcactatcag caaaggttgc aatcgctgta cttcaaaaag aagtttgcag agcgtgtggc   2400

agaagtgaaa cctaaagtgg aagcaattcg ttctggctca gaagaggtgt ttaggagtgg   2460

tgccctcaag cagttgctgg aggtggtttt ggcatttgga aattatatga ataaaggtca   2520

aagagggaat gcatatggat tcaagatatc tagcctaaac aaaattgctg acacaaaatc   2580

cagcatcgac aaaaacatta cccttttgca ctatctcatc actattgtgg aaaataagta   2640

ccccagtgtt ctcaatctaa atgaagaatt gcgagatatt cctcaagctg cgaaagtaaa   2700

catgactgag ctggacaaag aaataagtac cttgagaagt ggcttgaaag cagtagagac   2760

agagctggaa tatcagaagt ctcagccccc acagcccgga gataagtttg tgtctgttgt   2820

cagccagttc atcacagtag ccagcttcag cttctctgat gttgaagacc ttctagcaga   2880

agctaaagac ctgtttacta aagcagtgaa gcactttggg gaagaggctg gcaaaataca   2940

accagatgag ttctttggca tttttgatca atttcttcaa gctgtgtcag aagccaaaca   3000

agaaaacgaa aatatgagaa agaaaaagga ggaagaagaa cgtcgagctc gcatggaagc   3060

tcagctcaaa gaacaacgtg aaagggaacg taaaatgaga aaagctaaag agaatagtga   3120

agaaagcgga gagtttgatg accttgtttc agctttacgc tcaggagaag tgtttgacaa   3180

agacctttct aaattgaaac ggaatcgcaa acgtattacc aaccagatga ctgacagcag   3240

cagagagaga ccaatcacaa aacttaattt ctaattttcc atgaatactt ttttttagaa   3300

agctcattag cagccctcta aagtgactag aacgtttcat tacactgcct tgcaatccaa   3360

acagtggcaa ttttttcctt catctgtgag tgaatgtgtg aacgtgtgta tgtaaatgta   3420

tgtgtgtata tattaaaaaa tgtatataga tgtctgagtg ttgtctggag acctatacgt   3480

atggttaaaa agatttatgt taatgtatgt gctccaaaac ctttcgtgta tgcattcaca   3540

ttgagtgtgg ctcattttct ttccccgaac gccatgactg ttcagaagca caatactatc   3600

tcctgaaaga gataagagac attccctaga ttcaaaggca aaacagaaga aacaaacaaa   3660

caaacaaaaa aagcttgcaa aatattttat ggtttccaag cttgatatcc tttaaaatta   3720

ttttcattga tggaactgga gttgttggaa aaacatagat ttaaaatgat ttttgatagc   3780

tgacattgtg atgttgatgt atcacatcag taataggacc agctttgaat ttctgacatt   3840

ggtgtgggga tacagtctgt aaatgtttat tgagaacatc ttgcacacaa tttgaattat   3900

gtagaatgtc aatcaagttt ttgtatattt aaaagttgga catcaatttt ttcccctgat   3960

ttcatcaagt tatctctgcc aagtgctctt gataatttct tcagattttt ggaaaaaaac   4020

actatataaa tgcaatccat gcttttttta aagaacaaca ttgccagagt atgcttgttc   4080

taacaatata gatatataaa ccttaaaaat aataaaatat ctcacccaag acttaaagga   4140

agaattctct gaagggataa agattactaa aaaaaaaaaa aaaaaaaaaa aattaatggg   4200

gtgccttttt gttatagttt ctattttctg ttttgtagga caagctgcat tttctgtaaa   4260

tataggtctg gactaaagga tacataaaga atgcacaaaa tgtcaacatc agcagagatg   4320

cccagatcta tttatctcta agtatatttg aagtgattgc tgtttatatg ttgtcatttt   4380

aaaattgtgt gtcagtaaag ctacctgtaa aatttcagtc caaaaaaata aagctctcag   4440

ggagacatga ataaaatcaa tgaacattag aaaataaaat atagatgctt accattaacc   4500

taccaactct taatatcctt aaattatgtg atatataaag aggactgtta cttttttact   4560

tttttttttt tttttttttt tttttggctt tgctttattt atttgtagtt gggggctaac   4620

gttttctctt ttctttctat tgatcctgtt gtggttgggt ttcctgtgga gagagtagtt   4680

tgtcctgttg cactagaaca ttatttactc actaaattga gtttttcagt caattaacaa   4740

atatttatta agttcctact atgtaccagg catagtaggg ctacaatggt aagcaagaca   4800

gagtccctgc ccccaaagag cttatattct aatggggata ttaagggatg aatagaatac   4860

caatgtgtgc actgtacagg aatcatacta tttaaaaata atttgtataa actataatgc   4920

ttagcacaga tggcgagtta tctgtgctat gtgaaagctg tgaaatagtg ctctaagagt   4980

tgtcaagagc tgtggtttta catcttttcc tcattgcaaa tttagtgact ttctacacac   5040

tatatggaaa taaatgacta gcaaataaaa cagtcataaa tacaaagcag aggttgcact   5100

cccccaatcc cgagttaacc caggtctgca ataacaccat gttaaaggtg cagatagaga   5160

cttggctcaa aaaggcttgg agatgaggaa gattggaata taatgatggt tttgtctgtt   5220

ccttaactaa agtgcctcta tgtatattct tttctatttg tagcaggata aatttggtct   5280

ggctcagttt tggaactgta ttttgaaaat ggctttgtct tacagtttaa ggaatagaca   5340

ggtggaggga aagtcacata aaggagcaag tttgtgtagc tgtccctctt gcccctttta   5400

atcatcctcc tttgatatgg ccatcctggt gggcctcctt tgccatttcc atttttggtt   5460

tctttccctg aaaactgtgt gcaggtaatt ccatgtgcca ttgttgaaaa gaaaaaaaaa   5520

aaacaaaaaa aaaacctact ttttagattg gtgctggtgt aagtagccac ttttctctct   5580

tgggtgtgta ttttaaactt tttttgtttt tttaaattaa tgccaaaaag aaaatgcata   5640

atttgtaaac ttaattatat gtcttatatc ttattagctt agtagttgga accacttagt   5700

ctttaggtgc aagactgttg ttagatagta ctgagaaaaa aaaagtatgt gttatgagac   5760

tgtacatgtt tttttaaaaa tagcaatatg caataaagag atgaattcat tgggtgtaca   5820


<210>  1034
<211>  6301
<212>  DNA
<213>  Homo sapiens

<400>  1034
aggaagtgac tcaagaaaca gtttgcgtgc gatgtggaca agagaggtcc ccgctgggtg     60

aggaacccgg gaaggcccgc ccagattcgg gccccctgcc cttgtcccct gggctggggg    120

cgcgggcaaa gcgggggcct ggcgggcgct gagaggacct gaagccggcg cgggcggcgg    180

aggcgggctg ggggcagcag ccatgcctac ctggggggcc cgccccgcgt ccccagatcg    240

ctttgcggtg tctgcggagg ctgagaacaa ggttcgggaa cagcagcccc atgtggagcg    300

catcttcagc gtgggggtga gcgtccttcc gaaggactgt ccggacaacc cccacatctg    360

gctgcagctg gagggcccca aggaaaacgc cagcagagcc aaggagtacc tgaagggcct    420

ctgcagccca gaactgcagg atgaaatcca ctacccgccc aaactgcact gcatctttct    480

gggagcccag ggcttcttcc ttgactgcct ggcctggagc acgtcagccc atctggtgcc    540

cagggcgcca ggctcactga tgatcagtgg cctgactgaa gcctttgtca tggctcagag    600

ccgggtagaa gagctggcag agcggctgag ctgggacttc acgccaggac catcttccgg    660

agcctctcag tgtactggag tgctgagaga cttctctgcc ctgctgcagt ccccggggga    720

tgcccataga gaggctctgt tgcagttgcc cctggctgtc caggaggagc tgctgagtct    780

ggtgcaggag gcgtctagtg ggcaggggcc aggagcactg gcttcttggg aggggcggag    840

ctcagccttg ctgggtgctc agtgccaagg agtgagagct ccccctagtg acggcaggga    900

gtccctggac actggatcta tgggacccgg agattgcagg ggagcaaggg gagacactta    960

cgctgtggag aaggagggag ggaaacaggg tggtcccagg gagatggatt gggggtggaa   1020

ggagttgcct ggggaagagg cgtgggagag agaagtggcc ctcaggccac agtcagtggg   1080

tggaggggca agggagtcag cacccctgaa agggaaggcc ctggggaagg aggagatagc   1140

tctgggagga ggagggttct gtgtccaccg tgagcctccc ggtgcccatg gctcctgtca   1200

cagggcagct cagtcccgag gagcctccct cctccagcgg ctccacaatg ggaatgcctc   1260

tcctccgagg gtgcccagcc ctccacctgc accggaaccc ccatggcact gtggagaccg   1320

gggtgactgc ggagaccggg gagacgtggg ggacagggga gacaagcagc agggcatggc   1380

acggggtcgg gggcctcaat ggaaacgagg cgcccgaggg ggcaacttgg tgactggcac   1440

acagcgtttc aaggaggccc tgcaggatcc tttcaccctg tgccttgcca atgtgcctgg   1500

ccagccagac ctccgccata ttgtcattga cggcagcaac gtggccatgg tgcatggcct   1560

ccagcactac ttctccagcc ggggcattgc cattgctgtg cagtacttct gggaccgtgg   1620

tcaccgtgac ataactgtct ttgtgcctca gtggcgcttc agtaaggatg ccaaagtcag   1680

agagagtcac ttcctgcaaa agctgtattc cctcagcctg ctctccctca caccctcacg   1740

agtcatggat ggcaagagga tctcctccta tgatgacagg ttcatggtga agctggctga   1800

agagacagat gggataattg tctccaatga ccagttccgg gacctggcgg aggagtctga   1860

gaagtggatg gcaatcatca gagaacgcct gctgcccttt acctttgtgg gaaacctctt   1920

catggtacct gatgacccac tggggcgaaa cggccccacc ctggatgaat ttctgaagaa   1980

gccagccagg acacaggggt cttctaaggc tcagcatcct tccaggggct ttgcagaaca   2040

tggtaaacag cagcagggga gagaagagga aaaaggtagt ggtggcattc ggaagacccg   2100

ggaaacagag cggctccggc ggcagctgct ggaggtgttt tggggtcagg atcacaaagt   2160

ggacttcatc ctgcagcggg agccatactg ccgggacatc aaccaactgt ctgaggccct   2220

gctcagtctt aacttttgag cctcacctgc ttgagtggct gccgccctgt cagctccagc   2280

cgcctccagc tcagcccttt ctgtgagagt ccctctgctg ctcactctga tccagaggca   2340

ccctgagttg gtgctttgga tcagggaagc cactttggga caggtccata aagtgaactg   2400

atcttaccga gtcaggacct cagccagctc tcaagaggtt ctgctcagcc ttaacttctc   2460

aactttgcct tagcacaggg tttctgtagg gagtgggggc tgctagaggg gattagttcc   2520

ggagactgag actgttggct ccacctccaa gctgagctag ggtggagggc agggtgggca   2580

ggaagtgaca ggaagttaag ctgttcctct ccctggctgc tgctctggat ggccagagaa   2640

caagatgctc ccttgctgag ctcctgggag cgtggaagga gatgctaggc cctggcacag   2700

tgttatgtgg actgggccac gatagggtgg agtgagctag tgaagaaggc agagggagac   2760

ttggcttctg gtctcagcta tgcctgtttt gtgaccttga ttgagttgct tgggctttac   2820

ttctgcctac aaatcagggg taaaaatacc tgttgggagg agaaatgaga acatagagga   2880

aagcctcttg gaggaaaggt gcttggacca agtctcaggt gtgtctgcct gtggctgcac   2940

aggctctcta accgaaacct cactttcaga gagatgtggg tcctttgtct ccaggatcca   3000

caccctagat tttaacactg cattctcact ataacgtgcc ctataatggc tgcatccctt   3060

ttgagcaacc tccaaaatct acatttacac agtaggtaaa ttagggatga ctgcattatc   3120

aaaatactct cagggttcct ataaatggca gctctcctgt tgtattcagg tgttgtttac   3180

agactaacaa atgtgttggc aaatccctgg ttagatgcac ttcctggtgt tgagatgaac   3240

acgtcgattt ttcaccaatc gatgaagcca tgctctgcaa tgacaatatt aatgtgatcc   3300

gaccctaaca ttttctctat ggaagacgta tgttgcataa agcaaggcac acttctgctt   3360

tatgtgtgtg tgtatgggga tgggaggact taacggaagt tgaaccagtt ggttctagat   3420

gaaccaatta tctggaaaat gaaagaacca gagttggaag gcacttgact ggccaccaga   3480

ccaactctgc tgttactgac atgctttctt caccctgatt cctagaggtc attgccctgg   3540

atctgcttga agtcctcctg tgccagggaa tttactatct ccagggtagc acattccctg   3600

tgtagacggt attaatcagt actccttact ttagtgcagc ctaaagtatg cttttctgtt   3660

acatccacct ttgaggctgg tcatacctcc aggaacaata cagagccagt caacttcctg   3720

gaatccaaga ccagataaag aagtaggaca ggtgcccctg ggttctgttc tgtgtgggcc   3780

tgtggggagt ctctagacaa gatcttttcc aggccctgac ttctgcctcc ctctgagtgg   3840

cacagggagt tgaatactgc atggcgagtg taatgatgat ggggagggtc cttgtgtcct   3900

caccccttcc tttttggtga tttacaccac tgtaccatac tgacccaggc tgggggcagg   3960

tgtgttggag acaggctggt caaagaggtg acaatgatta agagataacc cagcggtccc   4020

tgagaagaga ttggttagta tggcctgaac tggtggctgg gggaactgtg tctggtcaag   4080

ttatggcaga tgtcacagct ttaggtaggt aaaaagggtc ctagatgaaa accttggagt   4140

tttttttttt cctgataggg ttgtttatac ttcttgattg gtttcttgcc attttcactt   4200

tcagtgatgg tgggtgtgca gtagaccaaa agtgtcttct gcccttttgt gctaagggcc   4260

ctggttgact gagtggcccc agtcagatga gaggcaagtc ctaagcttct tatagacagg   4320

gatgttgact ttgttctgct gcagcctgat aaactgggac cactgtgtgg ttagtaatgc   4380

acttgccatt tggtgacaca gactgaaggc tatcctacac ctgggcctta cctcttcctc   4440

tactggcatc ctaatggcac tctgacagca tccagggtga ctacagggcc cattggaaat   4500

ggatcatcat tctctcttct agtgtctatc tttatcataa cctgatgtcc caaacttgtg   4560

acaagttctt ttggcaactg aaggaccaag aagggaaacg gtgatgagag agactgctca   4620

ttgtaacttt caaaaccccg tctttgggga agaatcatct agggtgacat tccttgaagt   4680

aaatcccagg agaatctagg ccaaagagat gagccaaggt tagtgagaca atttattttt   4740

attgcctaaa ctgcagagca ttctctacac agcgtaaagg agaagtgggg cagctgcagg   4800

acatgtagag aaaccaaact gggaaatctt acaaggagtt gaaaagatta atgtcccaac   4860

ctgatgagat tacggccttg agacaataag gtggagcaac agaacaatgg gaaagaggac   4920

tgggagagga atctaagaac cagatggctt cagctctcta gaggagctga gcctattcac   4980

agtgcctaac ctggaagcct gtgaggaaca ggcctcaggc ccttgccacg acctacttag   5040

gctacaattt cctttaaggc agcccctagc tctgggaagg aatactggta gccagtggcc   5100

agtgttcgct gtgggatcac cttctggccc tccagcagca tgatggcacg ctgtcgccca   5160

aagacagctt gcaccacagc gctggggaga gggatgaagg ctcggcggcc cagggcagca   5220

cccaaggtct gggcaaactc agcattagtg gcggaggatg gagccactcc attcaggacc   5280

ccgtgcacgt ggtttgcttc aagggcatgg gtcaggattc ctgccaggtc cccgatgtgt   5340

atccagggga agaattggtg gcctgagccg atggggcccc ccaggcccag gcgaaagggc   5400

agcagcatgt ggcccatggc accaccccca cggcccagca caacccctag agcaggaaag   5460

agggaaggta caggggtcct ctcagccttg aaggagccca ctgctcctcc tggtttctgt   5520

ttccccttcc tcactctccc catgctgact tggctctgta acagaagtga gcagtatggc   5580

tgtctttaag acctcacacc ttctcatctg caggttggct agaagtggtg gcatcctctc   5640

actctgtaat tgtaatctca gctctcctaa tcccatcact tccccagccc agagaagaca   5700

ttccaaccct gtctgatacc caggcccgtt tctcacctga gcgcaccacc acctggcgtg   5760

tagaatctcc aggaagcctg gctgcagctt cccatttggt tacgaggttg gagaaaaagt   5820

caaagtcccc tcctgggctg tcttcatcat actccgcagt cagactgggc tggtagtaag   5880

ctgccggtgg aacacaatca tttgccctgg gtgtccttgg tcctgcctgg ctctctgtag   5940

tggaggctcc ccttggcctc accttctctg gcccttagga tctccccatt tggagacaga   6000

gccatttgga tattttcccc ttgaacttct ccatgacctg aagcgttcct tccctggagg   6060

aactctggtt gcagggctaa acttagaggc tgctagagtg tagtggttaa gaacaggaac   6120

ttgggtacca ggcgcctgaa ttttaatcag ctccctcatt tattaactct ctgacttgat   6180

gcaagttact taacctctct gtatagaatt ttcacatctt taaaatggga ataatagtac   6240

ctacctcata gggttgttgt aaggaataaa tgataataag cataaaacac ttcaaaaaaa   6300

a                                                                   6301


<210>  1035
<211>  3043
<212>  DNA
<213>  Homo sapiens

<400>  1035
ggtgccttag gcgctggaga aaaacttcac ccgcgcccac aggccccctt tccgcaggct     60

gcgctggcgg ttcaggtttg caggccggaa gtgaaatgtt cttttttgat ttttaaaaag    120

gaagcctccg gccctatggt tttctggggt tggagtggat gtgtgtgctg ggggaggcgg    180

agacgtcccg ctccaggcag ggccttgggt cttaataggt ggggaaatct ctgccaaata    240

ggaggcctct cggagcctca gtttccccat ctgcagactg ggctctgact tcttctggca    300

tgagagggtg tgtgagagta aaaggaggca gctagccccg tgccgggaga cacgtcagcc    360

atgtcatctg agcctccccc accaccacag ccccccaccc atcaagcttc agtcgggctg    420

ctggacaccc ctcggagccg tgagcgctca ccatcccctc tgcggggcaa cgtggtccca    480

agcccactgc ccactcgccg gacgaggacc ttctcggcga cggtgcgggc ttcacagggc    540

cccgtctaca aaggagtctg caaatgcttc tgccggtcca agggccatgg cttcattacc    600

ccagctgatg gcggccccga catcttcctg cacatctctg atgtggaagg ggagtatgtc    660

ccagtggaag gcgacgaggt cacctataaa atgtgctcca tcccacccaa gaatgagaag    720

ctgcaggccg tggaggtcgt catcactcac ctggcaccag gcaccaagca tgagacctgg    780

tctggacatg tcatcagctc ctaggagatg gtggaagcac cccttgtcct gtgcttgtgg    840

gagactttgc agggaggagg cagcagacac tggagatgac attcttccac acgagacggg    900

gcttcagccg ggcatggtcc ctctcaagta tctcctggag gaaggggtat ggggggcagg    960

tgtggggtgt ggggtgttcc cggccatcag cacagcctat gaccattgca acaacctctc   1020

accatctgaa gagcattaaa agcatttaaa aaggagaggt gcccactggt ggctgagtgg   1080

aggttccaac cccatcccag ggagtggatc aagggtggta tttctccagc tgctcagaca   1140

catgggctca acccacagaa tccctcttcc tcctggagct ggaggcccca gattcccaga   1200

tctggccccc tggcagcctg acagggacct tgcgtgactt ctccaaggca aatttccacc   1260

taagtgcccc ttgcgcctct cctggggcct gggcaaagca gttttctaat tcttggcttg   1320

gttggttcta ggggagctgg cttgaagtgg gtggggaaag gcgggggtgg cggtctttgg   1380

attggacgga tgttgccttt tggtgccttt gcagtgggag gcggcatagc tgcctgtctg   1440

gggaagacag ttctcccagc actcccaccc ctgggcacag caggctggta ctgggaggct   1500

gaacccctct tagagcctga ccttttcatc tgccttctgg ttgtgtgacc atcactcaac   1560

agccatttca cagcccctgt aattatggcg gcggggggct ggggtggtgg tggtgggaag   1620

ggcttgtgga gaggacacag tctttgttta aaaactttgt cccgatccat ccagaaaaga   1680

gtaggtagct tgcatcctga cagcctggca aagtcaagaa agttgaagga gaaacatacc   1740

tttggagagg gggttttctt taaaactagt gttaagaaat gcttagggat tttttttttc   1800

ttatttttca taactaaagc tttcacccag agccggctct gtttgcactt tgctgccgac   1860

attgcaaact ttttggcagg gtgggagact gagtctcatt ctgtcaccca ggctggagtg   1920

cagtggcccg atctcagctt actgcaacct ctgccctcca gggttctggc aattccgcct   1980

cagtctcctg agtagctggg attacaggca tgcgccacca cacccggtta atttttgtat   2040

ttttagtaga gaccaggttt catcatgttg ggcaggatgg tcttgaaccc ctgacctcag   2100

atgatctgcc catctcggcc tctcaaagtg ctgggattac aagtgtgagc catcgcgccc   2160

ggcctgcaaa cttttttgta ggtatttctg gtaaacaaat ccttaggtta tctttgctgt   2220

ggttgtggtt tggctttagt catgatttca aagtagaaat agctaggcat tattttttga   2280

aatatatgac ctatatgtag tcaagaatcc actgaacaga ggcaagcaaa ccttttggaa   2340

actggctttt gggcagacag taaacgtcca gtttgatgct ggaagcatga acagcttcat   2400

caggtaggta ctcctcaact ctgatgagtt tgtcctttca gcctaagggg gtggaaggga   2460

gttgtttgag aatagcaaat acgcatgttg attgcgagtg tgtggagaca aaggcagttc   2520

ccaccacagt taggtcctgg ccattgtttc ctcgcctgcg atgctccttg tacatcctca   2580

ccctcctctc ccgcctctgc cttctgctgg gtcaaaggtg gccttttctc tccagccttg   2640

aattgttccc tgttggcttc ccaagggccc atctgctggt acagtccaca cttccacagc   2700

caagacccga gagggctttc actgccccaa gcctctctcc tgtgaccctg ggattctgtc   2760

ttggcagaat cctttgtcag cggctcttac tctgtccttc ctgtttggcc acagctcttt   2820

caatcaatgg gtattctaga accgcaggat gtcagagctg gaagggacgc gataccggtt   2880

tacacaaggg gaaactcctc gaggctctgg gagggacgga gggttttggt gacagagcga   2940

gagctaaaat tgaggattcc tgaatccaga tcttgcctcc catcagccat ctttctccca   3000

ataaattttt gttttgtgca aggctaaaaa aaaaaaaaaa aaa                     3043


<210>  1036
<211>  2869
<212>  DNA
<213>  Homo sapiens

<400>  1036
cccttctccc cggcggttag tgctgagagt gcggagtgtg tgctccgggc tcggaacaca     60

catttattat taaaaaatcc aaaaaaaatc taaaaaaatc ttttaaaaaa ccccaaaaaa    120

atttacaaaa aatccgcgtc tcccccgccg gagactttta ttttttttct tcctctttta    180

taaaataacc cggtgaagca gccgagaccg acccgcccgc ccgcggcccc gcagcagctc    240

caagaaggaa ccaagagacc gaggccttcc cgctgcccgg acccgacacc gccaccctcg    300

ctccccgccg gcagccggca gccagcggca gtggatcgac cccgttctgc ggccgttgag    360

tagttttcaa ttccggttga tttttgtccc tctgcgcttg ctccccgctc ccctcccccc    420

ggctccggcc cccagccccg gcactcgctc tcctcctctc acggaaaggt cgcggcctgt    480

ggccctgcgg gcagccgtgc cgagatgaac cccagtgccc ccagctaccc catggcctcg    540

ctctacgtgg gggacctcca ccccgacgtg accgaggcga tgctctacga gaagttcagc    600

ccggccgggc ccatcctctc catccgggtc tgcagggaca tgatcacccg ccgctccttg    660

ggctacgcgt atgtgaactt ccagcagccg gcggacgcgg agcgtgcttt ggacaccatg    720

aattttgatg ttataaaggg caagccagta cgcatcatgt ggtctcagcg tgatccatca    780

cttcgcaaaa gtggagtagg caacatattc attaaaaatc tggacaaatc cattgataat    840

aaagcactgt atgatacatt ttctgctttt ggtaacatcc tttcatgtaa ggtggtttgt    900

gatgaaaatg gttccaaggg ctatggattt gtacactttg agacgcagga agcagctgaa    960

agagctattg aaaaaatgaa tggaatgctc ctaaatgatc gcaaagtatt tgttggacga   1020

tttaagtctc gtaaagaacg agaagctgaa cttggagcta gggcaaaaga attcaccaat   1080

gtttacatca agaattttgg agaagacatg gatgatgagc gccttaagga tctctttggc   1140

aagtttgggc ctgccttaag tgtgaaagta atgactgatg aaagtggaaa atccaaagga   1200

tttggatttg taagctttga aaggcatgaa gatgcacaga aagctgtgga tgagatgaac   1260

ggaaaggagc tcaatggaaa acaaatttat gttggtcgag ctcagaaaaa ggtggaacgg   1320

cagacggaac ttaagcgcaa atttgaacag atgaaacaag ataggatcac cagataccag   1380

ggtgttaatc tttatgtgaa aaatcttgat gatggtattg atgatgaacg tctccggaaa   1440

gagttttctc catttggtac aatcactagt gcaaaggtta tgatggaggg tggtcgcagc   1500

aaagggtttg gttttgtatg tttctcctcc ccagaagaag ccactaaagc agttacagaa   1560

atgaacggta gaattgtggc cacaaagcca ttgtatgtag ctttagctca gcgcaaagaa   1620

gagcgccagg ctcacctcac taaccagtat atgcagagaa tggcaagtgt acgagctgtt   1680

cccaaccctg taatcaaccc ctaccagcca gcacctcctt caggttactt catggcagct   1740

atcccacaga ctcagaaccg tgctgcatac tatcctccta gccaaattgc tcaactaaga   1800

ccaagtcctc gctggactgc tcagggtgcc agacctcatc cattccaaaa tatgcccggt   1860

gctatccgcc cagctgctcc tagaccacca tttagtacta tgagaccagc ttcttcacag   1920

gttccacgag tcatgtcaac acagcgtgtt gctaacacat caacacagac aatgggtcca   1980

cgtcctgcag ctgcagccgc tgcagctact cctgctgtcc gcaccgttcc acagtataaa   2040

tatgctgcag gagttcgcaa tcctcagcaa catcttaatg cacagccaca agttacaatg   2100

caacagcctg ctgttcatgt acaaggtcag gaacctttga ctgcttccat gttggcatct   2160

gcccctcctc aagagcaaaa gcaaatgttg ggtgaacggc tgtttcctct tattcaagcc   2220

atgcacccta ctcttgctgg taaaatcact ggcatgttgt tggagattga taattcagaa   2280

cttcttcata tgctcgagtc tccagagtca ctccgttcta aggttgatga agctgtagct   2340

gtactacaag cccaccaagc taaagaggct gcccagaaag cagttaacag tgccaccggt   2400

gttccaactg tttaaaattg atcagggacc atgaaaagaa acttgtgctt caccgaagaa   2460

aaatatctaa acatcgaaaa acttaaatat tatggaaaaa aaacattgca aaatataaaa   2520

taaataaaaa aaggaaagga aactttgaac cttatgtacc gagcaaatgc caggtctagc   2580

aaacataatg ctagtcctag attacttatt gatttaaaaa caaaaaaaca caaaaaaata   2640

gtaaaatata aaaacaaatt aatgttttat agaccctggg aaaaagaatt ttcagcaaag   2700

tacaaaaatt taaagcattc ctttctttaa ttttgtaatt ctttactgtg gaatagctca   2760

gaatgtcagt tctgttttaa gtaacagaat tgataactga gcaaggaaac gtaatttgga   2820

ttataaaatt cttgctttaa taaaaattcc ttaaacagtg aaaaaaaaa               2869


<210>  1037
<211>  4819
<212>  DNA
<213>  Homo sapiens

<400>  1037
ctgtcaggtg actctcccgt ggcgccatgg cggaagcaga ggagcaggaa actgggtccc     60

ttgaagaatc tacagatgag tctgaggaag aagagagcga agaggaaccc aagctgaagt    120

atgaaaggct ttccaatggg gtaactgaaa tacttcagaa ggatgcagct agctgcatga    180

cagtccatga caagtttttg gcattgggca cacattatgg caaggtttat ttacttgatg    240

tccaggggaa catcactcag aagtttgatg tagtgcaggt atttggactg tattctggag    300

aagaatttca cgagactttt gactgtccca ttaaaattat tgctgtgcac ccacatttcg    360

tgagatccag ttgcaagcag tttgtgaccg gagggaagaa gctgctactg tttgaacggt    420

cttggatgaa cagatggaag tctgctgttc tgcatgaagg ggaagggaac ataaggagtg    480

tgaagtggag aggccatctg attgcttggg ccaataatat gggtgtgaag atttttgaca    540

tcatctcaaa gcaaagaatc accaatgtgc cccgggatga tataagtctt cgcccagaca    600

tgtatccctg cagcctctgc tggaaggaca atgtgacact gattattggc tgggggactt    660

ctgtcaaggt gtgctcagtg aaggaacggc atgccagtga aatgagggat ttgccaagtc    720

gatatgttga aatagtgtct cagtttgaaa ctgaattcta catcagtgga cttgcacctc    780

tctgtgatca gcttgttgta ctttcgtatg taaaggagat ttcagaaaaa acggaaagag    840

aatactgtgc caggcctaga ctggacatca tccagccact ttctgagact tgtgaagaga    900

tctcttctga tgctttgaca gtcagaggct ttcaggagaa tgaatgtaga gattatcatt    960

tagaatactc tgaaggggaa tcactttttt acatcgtgag tccgagagat gttgtagtgg   1020

ccaaggaacg agaccaagat gatcacattg actggctcct tgaaaagaag aaatatgaag   1080

aagcattgat ggcagctgaa attagccaaa aaaatattaa aagacataag attctggata   1140

ttggcttggc atatataaat cacctggtgg agagaggaga ctatgacata gcagcacgca   1200

aatgccagaa aattcttggg aaaaatgcag cactctggga atatgaagtt tataaattta   1260

aagaaattgg acagcttaag gctattagtc cttatttgcc aagaggtgat ccagttctga   1320

aaccactcat ctatgaaatg atcttacatg aatttttgga gagtgattat gagggttttg   1380

ccacattgat ccgagaatgg cctggagatc tgtataataa ttcagtcata gttcaagcag   1440

ttcgggatca tttgaagaaa gatagtcaga acaagacttt acttaaaacc ctggcagaat   1500

tgtacaccta tgacaagaac tatggcaatg ctctggaaat atacttaaca ttaagacata   1560

aagacgtttt tcagttgatc cacaagcata atcttttcag ttctatcaag gataaaattg   1620

ttttattaat ggattttgat tcagagaaag ctgttgacat gcttttggac aatgaagata   1680

aaatttcaat taaaaaggta gtggaagaat tggaagacag accagagcta cagcatgtgt   1740

atttgcataa gcttttcaag agagaccacc ataaggggca gcgttaccat gaaaaacaga   1800

tcagtcttta tgctgaatat gatcgaccaa acttacttcc ctttctccga gacagtaccc   1860

attgcccact tgaaaaggct cttgagatct gtcaacagag aaactttgta gaagagacag   1920

tttatcttct gagccgaatg ggtaatagcc gaagtgccct gaagatgatt atggaggaat   1980

tacatgatgt tgataaagca atcgaatttg ccaaggagca agatgatgga gagctgtggg   2040

aagatttgat tttatattcc attgacaaac caccatttat tactggcttg ttaaacaaca   2100

ttggcacaca tgttgaccca attctactga ttcaccgtat taaggaagga atggagatcc   2160

ccaatttgag agattccttg gttaaaattc tgcaagacta caatttgcaa attctgcttc   2220

gtgaaggctg caagaagatt ctcgtagctg actctttgtc cttactgaag aaaatgcacc   2280

gaactcaaat gaaaggtgtt cttgttgatg aggagaacat ctgtgagtcg tgcctttccc   2340

ctattcttcc atcagatgca gctaagccct tcagcgtggt ggtcttccat tgccggcaca   2400

tgttccacaa ggagtgcctg cccatgccca gcatgaactc tgctgcacag ttctgcaaca   2460

tctgcagtgc taagaaccgt ggaccaggaa gtgcaatttt ggagatgaaa aaatagctca   2520

tttctccttg tcagtctcct tgtcaccact ctttttgaga ctgtttttgc aacaacaaaa   2580

gcatttgttg acactcgtgc tgttaagaga tttgtttatg tttatattat actcaaaaac   2640

aatttcttca tctattcctg tactaatggt ttctctttgc agttcacaga gaatttgggg   2700

ctctcttcat gccttgaaat tttggggtcc atagtgaata ttttgttatt tatttgtttg   2760

gctcattctt tatatagtaa tggaaacata agtctaggag ttagaaatga attttttaga   2820

ccttagtaaa accatttaac cataaaatgg acaactgaga attctcccag ctgcctgaaa   2880

gcgtcgccaa ctgtggttat cctgcaagct gctacctgca acttggacgt tgtttccacg   2940

tgctctgctg gctacgattc ttgcattctg ggtttggctt ttttctgtgt catcaactat   3000

ggttatcctc taaataggca tttaatgaaa cattgtacaa attgtcactc atttgatgac   3060

acctgggaat aacattagca ggctgatgtc ctgcaccatt atgtttacta atcacatgtt   3120

ctgtgtgctg tgacgactgt caaagagtat ctggccatgg cggacactca gcatttgttg   3180

attgaataaa tgttagctct tctcattgtg aaggactcac ttttactggg ataaacaaat   3240

gcagttaaga attctggcac ccttgtaagg aagaaaagag agttcaacac cttcgagtct   3300

gagcgcttgt ggctagagtt tgccaggagg gaggaaacca gtgaccctga aaactgaggg   3360

tgcctcagga gcagtgggac cacctgatgc tgaaggacgg actaatgatg tttcctcttg   3420

ccttctctgg tgcctccatt gccctcatgg aacagagcat atcatagagg gagaaaagtc   3480

aaacttgtaa ttgtgtctta cagttactgg cttcatcttc cttgggatat atggtcatcc   3540

tctaatgagt gtaaaagtgc gcaaaacaca tccttattgt tcctgatctc ttagtcccat   3600

aaatgggaac aaatacagct ttctgcttct ttctttttgg ggaaaggaca gggtgctagt   3660

gagtactgac agcatgccag ctaccgaagt cacccagcca ttcccatgag cagcagttca   3720

tttaattgtc acagcgtcgc caggaagaag atctgataaa cctaggttta cagataaaga   3780

aagcaaaatg tagagatgtt gttgaggtca cagaggtgac tgcctaactt cagagcaggg   3840

cttctgatcc ctttaagaaa ttacagggcc agccgggcat ggtggctcac gcccgtaatc   3900

ccagggcttt gggaggcctt ggcaggtgga tcacctgaga tcgcacgttc gagaccagcc   3960

tgaccaacat ggagaaaccc catctctact aaaaacacaa attagccagg cgtggtggta   4020

catgcctgta atcccagcta ctcaggaggc tgaggcagga gaatcacttg accccaggag   4080

acgtaggttg tggtgagctg agatcgcgcc attgcactcc agcctgggca acaagagcaa   4140

aactccgtct caaaaaagaa aagaaaagaa aagaaatcat agggccaagt tcaaaggaaa   4200

tgcacagaac atatcttcac attagagtta agaattctct agcaaacaac agattttttt   4260

gttgttgtta gtcacaaata cttagaactg gaaggctctt tgttattatt gaatgtaccc   4320

ctcagccttc tcagcatttc cttatcccaa gactagtgtg ctttctgcta cactgctagt   4380

tttcagtttt gttcttaccc aattgttttt tcttttcaac attaccaatt tacagattca   4440

gtttattaca tttacattaa tcctcactta tgatttgagc aagctcattt ccagaaaagt   4500

ttactttaag atcatcaata ggatttgcta atttcagtga agtcattttg cttcaggggt   4560

aaattatcct agttaccaag tcctatttgg acataaagaa aatcctactt atagaaaagg   4620

agaaaataat taaacagtct tcatttttaa gtaactgatt taaaaggaaa ataataaaat   4680

atgttcgttt atcatttcag aaattgctgt aacacactgg aaaattcctg aacaatatag   4740

attttatcgt taataaaaaa cactagcttt cgttccttag aatgtctttt cttttgaata   4800

aacagtattg ggtgattta                                                4819


<210>  1038
<211>  2725
<212>  DNA
<213>  Homo sapiens

<400>  1038
gcatttccgg agcgccaggg aagagggaag tcgtggtggt cgcgagggag ccggaaagat     60

ggtggttacc agatctgcac gggctaaggc cagcatccaa gccgcgtcgg ctgaaagttc    120

cgggcaaaag agttttgctg ctaatgggat tcaagcgcat ccagaaagta gtactggatc    180

tgatgcccga actactgctg aatcacagac cactgggaag caaagtttaa tccctagaac    240

tcctaaagct agaaagagga agagcagaac tacaggctca ctaccaaagg ggactgaacc    300

atctacggat ggagaaacct ctgaggcaga gtcaaattat tctgtgtctg agcaccatga    360

taccatttta agggtaacta ggagaaggca gatcttaatt gcatgctccc cagtgtccag    420

tgttaggaaa aagccgaaag taactccaac aaaggagtct tacactgaag aaatagtgtc    480

tgaagcagaa tctcatgttt caggtatttc tagaattgtg cttcctacag aaaaaactac    540

aggagccaga agaagtaagg ctaaatctct gacagatcca agccaagaat ctcatacaga    600

agctatatct gatgctgaga catcaagctc agacatttca ttctctggaa ttgcaactag    660

aagaaccagg agtatgcaga ggaaattaaa ggcacaaact gaaaagaaag atagtaagat    720

tgtaccagga aatgagaaac agatcgtggg tacacctgtg aattcagagg attcagatac    780

cagacaaact tcccatttac aagcaagatc tctttctgag ataaataagc caaatttcta    840

taataatgac tttgatgatg atttctccca cagaagttca gaaaatatat taacagtgca    900

cgaacaggcc aatgttgaat ctcttaaaga aacaaaacag aattgtaagg atttggatga    960

agatgccaat ggaataacag atgaggggaa agaaattaat gagaaaagtt ctcagctgaa   1020

gaatctttct gaacttcagg acactagcct tcaacagtta gtttctcaga gacattcaac   1080

cccccaaaat aaaaatgctg tatcagtgca ctctaatctg aactctgagg ctgtaatgaa   1140

atcattaact caaacatttg caactgtgga agtaggcaga tggaataaca acaaaaagag   1200

ccccataaaa gcaagtgact tgacaaagtt tggtgattgt ggtggtagtg atgatgaaga   1260

agagtccaca gttataagtg tcagtgaaga catgaacagt gaagggaatg tagattttga   1320

atgtgatacc aaactataca cgtctgcgcc caacacatct cagggtaaag ataattctgt   1380

cttactagtt ctcagcagtg atgaaagcca acagtctgaa aacagtgaga atgaagagga   1440

tactttatgt tttgttgaaa atagtggcca aagggagtca ttaagtggag acacaggaag   1500

tctgtcatgt gacaatgcat tgtttgtaat tgacacaact cctggaatga gtgctgataa   1560

aaatttttac ttggaagagg aagacaaggc aagtgaggtt gccattgagg aagaaaaaga   1620

agaggaagag gatgaaaaaa gtgaagaaga ttcatcagac catgacgaaa atgaagatga   1680

gtttagtgat gaagaagact tcctaaatag cacaaaggct aaacttctga agttgacaag   1740

cagcagcata gaccctggtc tgagtatcaa gcagttgggt ggtttgtata ttaattttaa   1800

tgcagataaa ctacagtcta acaagagaac cctaacacag atcaaggaga aaaagaaaaa   1860

tgagcttctg cagaaagccg tcattacacc tgattttgaa aaaaaccact gtgttccacc   1920

atatagtgaa tcaaagtatc aacttcagaa aaaacgcaga aaagaacgac aaaaaacagc   1980

aggggatggc tggtttggta tgaaagctcc agaaatgaca aatgaactga aaaatgatct   2040

caaagcactg aagatgagag ccagcatgga cccgaaaaga ttttacaaga aaaatgatag   2100

agatggcttc cccaagtact tccagattgg aaccattgtt gacaatccag ctgatttcta   2160

ccattcacga attcccaaga agcaaaggaa aagaactatt gtggaagaac tgctggctga   2220

ttctgaattc agaagataca accgaaggaa gtactcagag atcatggctg aaaaagcagc   2280

aaatgcagca ggaaaaaagt tccgaaagaa gaagaaattt cgcaattaag atttaccaag   2340

caaactgcaa cattttacat tgctccttta tttacttatt aaagacgttt ggaaaactaa   2400

caccatcatc taaattaatt taccatagac tggccctgtt catacaggaa tttgtatttg   2460

gaaaaagttg atttgagaat cgattacatg cccttagaaa ataggggtgt ctaaaagacc   2520

caccctggtg tagactcttt atgggaaaaa aggaaaaaaa atctcaacca ttttaagata   2580

actgatggtt tgtaaagttt tcaatgctta gttatttaaa gaaaatttaa ttaaaagata   2640

ggaagtataa agtttgctaa catgttcaaa gaactttaaa aaatgatcaa agatatataa   2700

acattattgt aattaatagg taaaa                                         2725


<210>  1039
<211>  4473
<212>  DNA
<213>  Homo sapiens

<400>  1039
gtcccgtccg acgctagggg gcgccgcagg ctgcctggcg cgctgctcgc ggcctcggag     60

ggccggggct gggtggcagc ggccatggac cgcttcgttt ggaccagcgg cctcctggag    120

atcaacgaga ccctggtgat ccagcagcgc ggggtgcgaa tctacgatgg cgaggagaag    180

ataaaatttg atgctgggac tctccttctt agtacacacc gactgatttg gagagatcag    240

aaaaatcatg agtgttgcat ggccattctc ctttcccaaa ttgtgttcat tgaagaacag    300

gcggctggaa ttgggaagag tgccaaaata gtggttcatc ttcacccagc tcctcctaac    360

aaagaacctg gcccattcca gagtagtaag aactcctaca tcaaactctc cttcaaagaa    420

catggccaga ttgagtttta caggcgttta tcagaggaaa tgacacaaag aagatgggag    480

aatatgccag tttcccagtc attacaaaca aatagaggac cccagccagg aagaataagg    540

gctgtaggaa ttgtaggtat tgaaaggaaa ctggaagaaa aaagaaaaga aactgacaaa    600

aacatttctg aggcctttga agacctcagc aaactaatga tcaaggctaa ggaaatggtg    660

gaattatcaa aatcaattgc taataaaatt aaagacaaac aaggtgacat cacagaagat    720

gagaccatca ggtttaaatc ctacttgctg agcatgggaa tagctaaccc agttaccaga    780

gaaacctacg gctcaggcac acagtaccac atgcagctgg ccaaacaact ggctggaata    840

ttgcaggtgc ctttagagga acgaggggga ataatgtcac tcacggaggt gtactgctta    900

gtaaaccgag ctcgaggaat ggaattgctc tcaccagaag atttagtgaa tgcgtgcaag    960

atgctggaag cactgaaatt acctctcagg ctccgtgtgt ttgacagtgg cgtcatggta   1020

attgagcttc agtctcacaa ggaagaggaa atggtggcct cggccctgga gacagtttca   1080

gaaaagggat ccctaacatc agaagagttt gctaagcttg tgggaatgtc tgtcctccta   1140

gccaaagaaa ggttgctgct tgcagagaag atgggccatc tttgccgtga tgactcagtg   1200

gaaggcctgc gtttttaccc aaatttattt atgacacaga gctaagggtt ttgtatttaa   1260

aatccttttt gtccatatgc ttgcgtcatg tagaggttgt atgacattga gctaagagat   1320

aaaccccgat caattgagaa tttattggaa cttcacagtg caatgtaaat ctcttttaat   1380

ttctcactaa atatggtcca ggaaatttat ttagtatacg cataggaaaa ttcagaaaag   1440

tgaatgccaa tatgaattta aaatcatgct atagtgcaga accctcagag tttaacttgg   1500

aatatagtgg attttaactt gatcctcaaa tctaatcatt ttataaagaa gggaatttag   1560

ttttgcagag aataaaaaga gaagttgcat gttcagacag gttagattat tattttggtg   1620

taactgaaat tcactgattg cacatgacaa tgttgggaca aaatatactg cagcatgcta   1680

tatgaggctc ctccccaggg cttttagaag cagtcataga catgtcttca acataccaaa   1740

taaaatacct ttaaaaatga aataatttta tttgacacat atatttatat atattctatc   1800

tagtttctct ttgttttttt aagtgatgat ttcatgactg gcatttaaag aatgcaactg   1860

tgtcattttg tttccaaatg ctgtggattt tgaaactgaa ctagagagct gtatagacat   1920

gcccagagtt atgattacaa atttaggagg tagacggctc aggaattccc tgggattgtt   1980

gtgctggtgg aatggcagag ggaacttcac aggaacctta gtgttctttt acctcaaagc   2040

cacagacagg aaatagaaag tggaaaagta atatctcctt ttcttttcca taaggagttt   2100

caacactgaa ctttaaaaag tctatcatat tccagcaata ttttttcttt gtcctttatg   2160

ttgtaagttg tgtggaaaaa ctacttcggt aagaaatgtt actgagataa caacaactgg   2220

ctaatactgc atgtagattg cttaggtttt aaagtgactg cctgacttca catgttattg   2280

ctacagcctc cagtatgttc gcattatctc aaactcaggg accccacagg acaggagaca   2340

ccctttctga aactgagttg gaagtgaaag ggtggtgatg gttttggcca agcctgcggg   2400

agggaaagta ttgtattggg agcacccttg ggaccaggaa gagggatgcc caggttcaca   2460

ctctgggacc cctaagacat tgtcagtggg taaggtggag ggccactgcc agaggctgct   2520

gcagtgccct ctgggaagtg ccagggaccc tcagctgcag acccagggga tcccaatccc   2580

ttatctctgc ctgaaaagtg gctattgctg cttcgtatcc tccagtgtca caggaatgct   2640

gtgcctgaga catcccactt tagtttttgt tttccaaacc tgtcactgac tcttcattgt   2700

ggtgacagat cctctggttc ccccattgct cagcctcagg tttattttga gggtaactca   2760

gtgtctgact gcccaagtct tttaggggtt agttggacca ttgtgtaagc ttgtttgtat   2820

gtctcacctc tttctggttg gtacttactg tctcacactg ctctggcaaa cttgtacaca   2880

cacacacact ctctctctct ctcacctggc taaggctttt aaaattatga agataaataa   2940

tctgtttcac cagctggagt gagttgcaag gaagattgct ggagctactc aatctagcgc   3000

taatggtttg gattcattac tgcaaaccta cataatttaa catatttgtt tactttagtg   3060

tgacaactga tgaaaaaaaa tggagcaatc tgaattgtat aaaataactt aagaaggaag   3120

aaaagtgata tataaatata ttttgcaaat gtcacattaa tttaaaaatg agtatgattg   3180

attttatttt taaagtgggc attcttcact gtttcgagac ctttgtatgt atttgtgtat   3240

ttttatcttt ttttttcagg ccattattat aaggtgttat tttggccctc taatgtagaa   3300

gttatgttta aatacaacca atcaggccct aagtgcaaaa aagttctgtc ttggtgctta   3360

tcactggtat aattattatt tttttgtttt cctaactttg ctcttaggag catgagcctc   3420

tttgtagctt tatggtaatg caatatttct ggtcatttac tgtcaaaaaa tttttttaca   3480

ttgtgttagt gaagactgtg ttttcagggt taaatgattg gtatcaatgt atatagagta   3540

aaattattgc aaaatttaaa aatgattttt cttggcattc tttttaaata ctctgaaaca   3600

tatatgcaaa tgagaaacct ttaatcatac taaagccagt tatgttaaga atttttcctt   3660

tggattttat aattaagagt tgcttataaa tacttatgac attgagctct tactgtttta   3720

gttgtcttaa aacaatggga catgtcatga actggtttct ttttttaaaa aattcttgat   3780

gtgaattcca ctgttacctg accatgtata ttcagatgaa tgtactcttt cttgttcctt   3840

gttaccagat taatctgaga gaatgtggat tcatcctgtc atctttctca tactcaaata   3900

cttaaaatgg ttcttttgcc caaaagtctc agagtcttca ttttggtaca gtggagtcac   3960

aacttgtaag gtggttaggt tttaaagacc gtgcctaagg acaaaattga gcatgctcag   4020

aatggtcctt gaaaatctcc taaattacca ataaatttct ctttgtagtc ttaaagttta   4080

aatccctgtg gagtgatatg taggtatgaa tatattatgc ttatattaag tacaaaaata   4140

caaactgcat atcaagagat tcttatagca ttaataattt ccatgcatgt gtctttttcc   4200

agtaggtatg gttgaattta tgtaaattta ttgctaatcc catcccttac gatctagagt   4260

ataagctgcg caagggcaga agtttttatc tggtttgttc atggatgtat tctaagagct   4320

gagaacaggg cctggacaca ataagcattc aataaatatt tactgaatga atgaactcct   4380

acctatattc ctatttataa tttggctcca ctttatccta ctttagctcc cattcaattc   4440

aataaaaaaa acattttttt gaacacatag caa                                4473


<210>  1040
<211>  2043
<212>  DNA
<213>  Homo sapiens

<400>  1040
gtcggggcgg gggctggggg tggagcctca tgccccgccc cgcggctggg ccctgccgcg     60

ccgctgcggc tcctcctccc tccttccgtc ctccgcgcct tccgtcggtc ggtccttgct    120

tcctgcttcg cctccgcgcc tcgcgctatg ggacagagcc cccgatccgc cagcaccacc    180

tgaggatcca gaaaccgccc cagcgatgga agaggatcag gagctggaga ggaaagcaat    240

agaagaactg cttaaggagg caaaacgtgg gaaaactaga gctgaaacaa tgggacccat    300

gggttggatg aagtgtcctc ttgctagcac caataaaaga tttctaatta acacaattaa    360

aaacacattg ccctctcata aagagcaaga ccatgaacaa aaagagggcg ataaggaacc    420

agcgaagagc caggcccaga aagaagaaaa cccgaagaaa cacagaagcc atccttacaa    480

gcacagcttc cgcgctcgag gttccgccag ttactccccg ccacgaaagc ggagcagcca    540

ggacaagtac gaaaagcggt ccaaccggcg gtgaggctgg aaccagggcc agccagccct    600

gcgggcctcc gtgctccttc ggggtgcggt gtgcggagaa ggcctgagct ggcagggcaa    660

acacctgaga gtgactttga cattaggtcc tttgttgttt ttaaagaggc tgctggccac    720

aggcaaaaaa aatgacctag caactcttga ggaaacaagt gcaaaggagg atgtcttggc    780

aagtttaagc tacttctgca gtgtagtaga cttacatatt gttgtttatc ttgtttggaa    840

gtgtgtttca aaataaacat gtctagaatt taaagttttc agagattgtt aaaactggtt    900

ccaatttttt ggtcatttct cagaaaaata aaatacttat aaatcctata ttttactttt    960

tgggggtatt acatttaaaa tttagaaatc atcagtccag tgaccatatt tatgaaaagc   1020

tgtagccctc caaggtctgg gaatttatcg agaagctctt tgatagctct gcatttgttt   1080

tcccttaggt gaacaatgta ggaaatcctc aaagtggctt tgaatttaat gctccacttc   1140

agttaccaga ggttaaaaat gggttttgtt gtttcctgtg cattctcaaa ctcatttatt   1200

agatagaaca atctttctat atttaatttt tttaatatat aggtcttaag tggtgcttta   1260

aaaagaaccc tcacaagtta aaaattaaga gttgtttcag tgctagatct taccagctaa   1320

agacttgtga taccactata tagtatagtt gttccagaaa tcttcatttt aaatagaagt   1380

gtttacaatg ccttttttcc cccagtattg gttttcaata cctgttttca tatacaatta   1440

caaacctttc aaacctgtat tccttcttta tactcaggaa aatgtcacca agcaccctcc   1500

tccccagttc acaaaaggaa gaagatgaag attctgtctc cctgttcccc ctccccagtt   1560

ttccaaagtg tctgagcata tgcctggctg tcctcagatc atcaccatgc cacatccctg   1620

ctccctactt cctggcagcc aagaaaagcc ctttctacat gctagaagga aatacatcca   1680

aaaagttagc attggagtgt tagaaactag aatagacctc tccgccaccg agctgctgtg   1740

tcacgccctc agcctgctag ggagtgacaa gcccaagtca ttcttgatcc accccttctc   1800

ccaccccaga tcccagggac tcatcctgtg actttgtaac cacactcatt cctttcaaac   1860

acagaggagg aattattgct tcatctgact ttattcaaat ctagttatgt attggcctaa   1920

attatttgtg caaaatttga aatgtttttt atttaaatat tagaaatagc acaaagtcat   1980

ggagttttta aaaattgtta taattaagta aaaataaagc tgaattgtgt catttgtgta   2040

tgc                                                                 2043


<210>  1041
<211>  1765
<212>  DNA
<213>  Homo sapiens

<400>  1041
tcccacaccc gacgctctgg cccacacaga cgctactctg tagcatctca ggttccctct     60

ggctgcactc tggaggacca cactcgtttt ctttttggct gccagaggcc cccgcatcca    120

ccgctgagct gggagaaaga tggcggcagc cgtgcgacag gatttggccc agctcatgaa    180

ttcgagcggc tctcataaag atctggctgg caagtatcgt cagatcctgg aaaaagccat    240

tcagttatct ggagcagaac aactagaagc tttgaaagct tttgtggaag caatggtaaa    300

tgagaatgtc agtctcgtga tctcgcggca gttgctgact gatttttgca cacatcttcc    360

taacttgcct gatagcacag ccaaagaaat ctatcacttc accttggaaa agatccagcc    420

tagagtcatt tcatttgagg agcaggttgc ttccataaga cagcatcttg catctatata    480

tgagaaagaa gaagattgga gaaatgcagc ccaagtgttg gtgggaattc ctttggaaac    540

aggacaaaaa cagtacaatg tagattataa actggagact tacttgaaga ttgctaggct    600

atatctggag gatgatgatc cagtccaggc agaggcttac ataaatcgag catcgttgct    660

tcagaatgaa tcaaccaatg aacaattaca gatacattat aaggtatgct atgcacgtgt    720

tcttgattat agaagaaaat tcattgaagc tgcacaaagg tacaatgagc tctcttacaa    780

gacaatagtc cacgaaagtg aaagactaga ggccttaaaa catgctttgc actgtacgat    840

cttagcatca gcagggcagc agcgttctcg gatgctagct actcttttta aggatgaaag    900

gtgccagcaa cttgctgcct atgggatcct agagaaaatg tatctagata ggatcatcag    960

aggaaatcaa cttcaagaat ttgctgccat gctgatgcct caccaaaaag caactacagc   1020

tgatggttcc agcatcttgg acagagctgt tattgaacac aatttgttgt ctgcaagcaa   1080

attatataat aatattacct tcgaagaact tggagctctt ttagagatcc ctgcagctaa   1140

ggcggaaaag atagcatctc aaatgataac cgaaggacgt atgaatggat ttattgacca   1200

gattgatgga atagttcatt ttgaaacacg agaagccctg ccaacgtggg ataagcagat   1260

ccaatcactt tgtttccaag tgaataacct tttggagaaa attagtcaaa cagcaccaga   1320

atggacagca caagccatgg aagcccagat ggctcagtga atccttgcag aacttctgtg   1380

cacatgacat ctttttccat gttgtgcaga tcagtttcac tatctccaaa gcatttgcat   1440

catgacctta tacatttcaa tcccttttat gctggattcc gtttaaagaa gacattatta   1500

gagcaggaag tacaagcatt taaaatatgt agttcccata tatttcaggg tctctgtgta   1560

ttaagctaac tcagatgttt tgaaagcttt ttctttaaac agaggtgaaa tatctgtggc   1620

taaaaagttt gagatttgtg ataactttgt agtcatgtaa aacttaagtg cttcatgcct   1680

ctccaaatgt ggttattcta ataaatggag aaatgagcca aataaaagta gtactttgtt   1740

tttagttaaa aaaaaaaaaa aaaaa                                         1765


<210>  1042
<211>  1853
<212>  DNA
<213>  Homo sapiens

<400>  1042
gagggtctgt ggtcctctga tcaacatagg ctggtgggag tacaggactc gcctcctcag     60

ggttccctgt gctgccactt ttcagccatg gccacaagtg aacagagtat ctgccaagcc    120

cgggcttccg tgatggtcta cgatgacacc agtaagaaat gggtaccaat caaacctggc    180

cagcagggat tcagccggat caacatctac cacaacactg ccagcaacac cttcagagtc    240

gttggagtca agttgcagga tcagcaggtt gtgatcaatt attcaatcgt gaaagggctg    300

aagtacaatc aggccacgcc aaccttccac cagtggcgag atgcccgcca ggtctacggc    360

ttaaactttg caagtaaaga agaggcaacc acgttctcca atgcaatgct gtttgccctg    420

aacatcatga attcccaaga aggaggcccc tccagccagc gtcaggtgca gaatggcccc    480

tctcctgatg agatggacat ccagagaaga caagtgatgg agcagcacca gcagcagcgt    540

caggaatctc tagaaagaag aacctcggcc acagggccca tcctcccacc aggacatcct    600

tcatctgcag ccagcgcccc cgtctcatgt agtgggcctc caccgccccc cccaccccca    660

gtcccacctc cacccactgg ggctacccca cctcccccac ccccactgcc agccggagga    720

gcccaggggt ccagccacga cgagagctcc atgtcaggac tggccgctgc catagctggg    780

gccaagctga gaagagtcca acggccagaa gacgcatctg gaggctccag tcccagtggg    840

acctcaaagt ccgatgccaa ccgggcaagc agcgggggtg gcggaggagg cctcatggag    900

gaaatgaaca aactgctggc caagaggaga aaagcagcct cccagtcaga caagccagcc    960

gagaagaagg aagatgaaag ccaaatggaa gatcctagta cctccccctc tccggggacc   1020

cgagcagcca gccagccacc taactcctca gaggctggcc ggaagccctg ggagcggagc   1080

aactcggtgg agaagcctgt gtcctcgatt ctgtccagaa ccccgtctgt ggcaaagagc   1140

cccgaagcta agagccccct tcagtcgcag cctcactcta ggatgaagcc tgctgggagc   1200

gtgaatgaca tggccctgga tgccttcgac ttggaccgga tgaagcagga gatcctagag   1260

gaggtggtga gagagctcca caaggtgaag gaggagatca tcgacgccat caggcaggag   1320

ctgagtggga tcagcaccac gtaaggggcc ggcctcgctg cgctgattcg tcgagcccat   1380

ccggcgacag aggacagcca gaagcccagc cagccccaga ctccagtgca ccagagcacg   1440

cacaggagcc tgggcgcgct gctgtgaaac gtcctgacct gtgatcacac atgacagtga   1500

ggaaaccaag tgcaactcct gggttttttt agattctgcc tgacacggaa caccaggtct   1560

gctcgtcttt tttgtgtttt atatttgctt atttaaggta catttctttg ggtttctaga   1620

gacgccccta agtcacctgc ttcattagac ggtttccagg ttttctccca ggtgacgctg   1680

ttagcgcctc agctggcggt gacagccggc ccagcgtggc gccaccacac accgcagagc   1740

tgtccaggca cagctccgtc cccagcgctc atggtgttga aactgtctgt catgcaccac   1800

ggtgtctgtg tccacacagt aataaacggt ttactgtccg caaaaaaaaa aaa          1853


<210>  1043
<211>  2607
<212>  DNA
<213>  Homo sapiens

<400>  1043
aggaggaggg gccggcagcc tggaagggaa aggacagcgg agagcagggc agagcctgag     60

caggcagggc acctccaggt gggcaggagc taccactcag caccatgagc accgccacag    120

gcccagaagc tgccccaaag ccaagcgcca agtctatcta tgagcagagg aagcgttact    180

ccacagttgt tatggctgat gtatcccagt acccagtcaa tcacctggtg acgttctgcc    240

tgggtgagga cgatggcgtg cataccgtgg aggatgcctc caggaagttg gccgtcatgg    300

atagccaggg ccgagtctgg gcacaggaga tgctgctgcg agtgtctccc gaccatgtca    360

cgctgctcga cccggcctcc aaggaggagc tggagtcgta cccactgggc gccatcgtgc    420

gctgtgacgc ggtgatgcca cccggcagga gccgctcgtt gctgctgctc gtgtgccagg    480

aacccgagcg cgcgcagccc gacgtgcact tcttccaggg cctgcgcctc ggggcggagc    540

tgatccgaga ggacatccag ggggctctgc acaattaccg ctcgggccgc ggggagcgca    600

gggcggcggc gctcagggcc acgcaggagg agttgcagcg cgaccgctcg cccgccgctg    660

agaccccgcc cctgcagcgc cgcccgtcag tccgcgcagt gatcagcacc gtagagcggg    720

gcgcgggccg cggacgaccc caggcgaagc ccattcccga ggcagaggag gcgcagaggc    780

ctgagccggt ggggacctcg agcaacgctg actcggcctc cccggacctg ggtccccggg    840

gtcctgacct ggcggttctg caggcggagc gggaagtgga catcctgaac cacgtgttcg    900

acgacgtaga gagctttgta tcgaggctgc agaagtcggc ggaggcggcc agggtgctgg    960

agcaccggga acgcggccgc aggagccggc gccgggcggc tggggagggc ttgctgacgc   1020

tgcgggccaa gccgccctcg gaggccgagt acaccgacgt gctgcagaag atcaagtacg   1080

ccttcagcct gctggcccgg ctgcgcggca acatcgccga cccctcctct ccggagctgt   1140

tgcacttcct tttcgggcct ctgcagatga ttgtgaacac gtcggggggg ccggagttcg   1200

cgagcagtgt gcggcggccg catctgacat cggatgccgt ggcgctgctg cgggacaacg   1260

tcactccacg tgaaaacgag ctctggacct cgctggggga ctcgtggacc cgccccgggc   1320

tggagctgtc cccggaggag ggacccccat acagacccga gttcttcagc ggctgggagc   1380

cgccggtcac tgacccgcag agccgcgcct gggaggaccc agttgagaaa cagctacagc   1440

acgagcggag gcgccggcag caaagcgccc cccaggtcgc tgtcaatggt caccgagact   1500

tggagccaga atctgagcct cagctggagt cagagacagc aggaaaatgg gtcctgtgta   1560

attatgactt ccaggcccgc aacagcagtg agctgtcggt caagcagcgg gacgtactgg   1620

aggtcctgga tgacagtcgt aagtggtgga aggttcggga cccagcgggg caggagggat   1680

atgtgcccta caacatcctg acaccctacc ccggaccccg gctgcaccac agccaaagcc   1740

ctgcccgcag cctgaacagc actcctcctc caccaccagc cccagccccg gccccacctc   1800

cagctctggc tcggccccgc tgggacaggc cccgctggga cagctgcgat agcctcaacg   1860

gcttggaccc cagcgagaag gagaaattct cccagatgct catcgtcaac gaggaactgc   1920

aggcgcgcct ggcccagggc cgctcgggac cgagccgcgc agtcccaggg ccccgcgccc   1980

cggaaccgca gctcagcccg ggctcggacg cctccgaggt ccgcgcctgg ctgcaggcca   2040

agggctttag ctccgggacc gtggacgcgc tgggtgtgct gaccggggcg cagcttttct   2100

cgctgcagaa ggaggagctg cgggcggtga gccccgagga gggggcacgt gtgtacagcc   2160

aggtcaccgt gcagcgctcg ctgctggagg acaaagagaa agtgtcagag ctggaggcag   2220

tgatggagaa gcaaaagaag aaggtggaag gcgaggtgga aatggaggtc atttgacctg   2280

ccaggcgccc ttcgcaaaga gtgacgaggc cccgtgggag aacggactcc tcagactctc   2340

cccaatagcg gaagtcgatc ttctgaagga tggccaatct gctccggccc tggtcttccc   2400

ccatcccggt ggacagactt aacgatcctt gctgcagtcc ctccggagag gatctggact   2460

ggctgggagt ggggagggcg tggagacagt ctacggaaag cgctagcaga cccccgagag   2520

ggtgcagtgg agccctgagc attgtaatat gcggcccagc ctataaacag cctccgtgct   2580

tagcaaaaaa aaaaaaaaaa aaaaaaa                                       2607


<210>  1044
<211>  2408
<212>  DNA
<213>  Homo sapiens

<400>  1044
ccgatccagc gtctccgttg ccaggaaaac agagcggcgc gctttccggc gcagtcgcgg     60

cgcgtcgcag ctgtcatggc ggagaccgtc tggagcactg acaccgggga ggcagtgtat    120

cgctcccggg accccgtgcg caacttgcgc ctccgagtcc acctgcaaag aatcacatca    180

agcaactttc ttcattatca gcctgctgcc gagctcggga aggacctcat agacttggcc    240

acttttaggc ctcagccaac tgccagtgga caccgcccag aggaagacga agaggaggag    300

attgtgattg ggtggcagga gaagctcttt agccagtttg aagtagatct gtaccaaaat    360

gaaacagcct gtcagagtcc tttggattat cagtaccgtc aggagatcct gaagctggag    420

aattcgggtg gcaagaaaaa ccgacgaatc tttacctaca ctgactctga tagatacacc    480

aatttggagg agcactgtca gagaatgacc actgcagcca gcgaggtgcc ttcattcttg    540

gtcgagcgaa tggcaaatgt caggcgtcgc cggcaggaca ggcgagggat ggagggcggc    600

atcctcaagt cacgcatcgt cacctgggag ccctcagaag agtttgtcag gaacaaccac    660

gtcattaaca cccctcttca gacaatgcac atcatggcag acctggggcc ctataaaaag    720

cttggctata agaagtatga acatgtcctg tgtactctga aggtggatag caatggtgtg    780

atcacagtaa agcctgactt cacgggcctc aaaggaccct acaggattga gacggagggg    840

gagaagcagg agctgtggaa atatacgatc gacaatgttt ccccccacgc acagccggag    900

gaggaggagc gggaacggcg agtgttcaag gatctttatg gccggcacaa ggagtatctc    960

agcagcctcg taggcaccga ctttgagatg actgtcccag gtgccctccg gctctttgta   1020

aatggagagg tcgtttcagc ccaaggctat gagtatgaca atctctacgt ccacttcttt   1080

gtagaattgc caactgctca ctggtcaagc ccagcattcc agcagctctc aggagtaaca   1140

cagacctgca ccaccaagtc cctggcaatg gacaaggtgg ctcacttctc ctacccattc   1200

acgtttgaag ccttcttcct ccatgaggat gaatcttctg atgcactccc ggagtggcct   1260

gtgctctact gtgaggtcct ctcgctggac ttctggcaga ggtaccgtgt ggaaggctat   1320

ggggctgtgg tgctgcctgc cactccaggc tcacacaccc tgacagtctc cacgtggaga   1380

cctgtggagc ttggcacggt ggctgagctg aggaggtttt tcattggcgg ttctctggaa   1440

ctggaggacc tctcctatgt acggatacca ggatccttca agggggaacg cctgagccgc   1500

tttggactcc gcacagagac cacaggcact gtcaccttcc gcttgcactg tctgcagcag   1560

tccagggcct tcatggaatc gagctccctt cagaaaagga tgcggagtgt gttggaccgt   1620

ctggaagggt tcagccagca gagttccatt cacaatgtgc tagaggcctt ccgtcgagcc   1680

cggcgccgca tgcaggaggc ccgggaaagc ctcccgcagg acctagtgag cccctctgga   1740

accctggtct cctagctcac agcagccctg gcccacagtg caagaggaca agatggggga   1800

tatctgaggc cagtgctctc ctgcctcttc gtctttctga ttagagacca cgttggtctg   1860

ctgagaacca gaaaagctgg gaaattcccg gctggcccct ctgcctagcc ttctgcaggg   1920

tcttctccct accctgtgga aataaagcca gagaccctgt ggccccccct ttatatttgc   1980

agccactgtc aatgggcatc acagcaaggc aggctttttg atctgaagct gtttggggtg   2040

accccatagt gagtctggcc ttgactcact tttctggctt gtctcacagt agcaggggat   2100

ctgctgttct ccacccttta aaaatggagc ctttcatctt ccaagaccaa agaaggaagg   2160

aaggtggacg gtgagagggt cttaaatccc cagcctgtga gtctcagcct ctttccaggg   2220

aagcctcatt ctactgcttg gggcttgctg aggttgagat atgagttatt tctgagtaag   2280

tgaaggctga aggcagtgct gagtcctttc tgctagctgg gtggtatctt ttactgtgtt   2340

tttttgtttg tttgtttttt tgttttttgt tacataaacc ccttttattt tgactgataa   2400

aaaaaaaa                                                            2408


<210>  1045
<211>  1699
<212>  DNA
<213>  Homo sapiens

<400>  1045
agcgacgact tccgccctcc ttagggccgt ggtcccgtag ctaccggtcg cgtcgccgtg     60

ggcgacgtgc ccgcttccaa aatggcggcg gcggcggtat ctggtgcgct tggccgggcg    120

ggctggaggc tcctgcagct gcgatgcctg cccgtggccc gttgccgaca agccctggtg    180

ccgcgtgcct tccatgcttc agctgtgggg ctaaggtctt cagatgagca gaagcagcag    240

cctcccaact cattttctca gcagcattct gagacacagg gggcagaaaa acctgatcca    300

gagtcttctc attcaccccc caggtataca gaccagggcg gcgaggagga ggaggactat    360

gaaagtgagg agcagttgca gcaccgcatc ctgacggcag cccttgagtt tgtgcccgcc    420

cacgggtgga cagcagaggc gattgcagaa ggagcccagt ctctgggtct ctccagtgca    480

gcagccagca tgttcgggaa ggatggcagt gagctaatac tgcattttgt gacccagtgc    540

aatacccggc tcacacgtgt gctagaagag gagcagaagc tggtacagtt gggccaggcg    600

gagaagagga agacagacca gttcctgagg gatgcagtgg aaaccagact gagaatgctg    660

atcccataca ttgagcactg gccccgggcc ctcagcatcc tcatgctccc tcacaacatc    720

ccgtccagcc tgagcctgct caccagcatg gtggatgaca tgtggcatta cgctggggac    780

cagtccactg attttaactg gtacacccgc cgagccatgc tggctgccat ctacaacaca    840

acagagctgg tgatgatgca ggactcctct ccagactttg aggacacttg gcgcttcctg    900

gaaaaccggg ttaatgatgc aatgaacatg ggccacactg ccaagcaggt aaagtccaca    960

ggagaggcac tggtgcaagg actcatgggt gcagcagtga cgctcaagaa cttgacaggt   1020

ctaaaccagc gtcggtgaga ggaaggggta taagctacaa tgcctagaag agaatgagcg   1080

gacagattga aagagctttg aaaagtataa ggtgccatcc acataacctg gtgttcacga   1140

gaacacacta aaggactcct gagtcactac cacagccacc tggaaaccac aaggcatttg   1200

atgctaccgt tctggtcagg gattgggctg cttcttcagt tcctaatacc agaccaagcc   1260

tcctgatgcc tttctgcact gcaactgtgt gattgaaaaa tgagatgttc atccaagcag   1320

tcaagccaca gaaacccagc atgtccctgt cacaatctca tgggcacctt gatcatgtct   1380

taaccttccc ttaaccttgg ggctcccaag ccagagtcaa ggtctgacgc cacctcaagg   1440

tgacagctca tctccagcac agcacaggcg tgtgcacaca gaggtgttcc ttgcagcccc   1500

ctccctctca ggtgtcctga gatgctgttc ctgggagccc cctcagaaaa ctgcctcacc   1560

tgagacaagt gcctgctgga cagaggtgtg attccaggcc tggtgtcaca tgacaccagc   1620

atgcattgca ggattattag tgtattttga gtctgtaaaa ataataaata tgtttgaagt   1680

agtttcccaa aaaaaaaaa                                                1699


<210>  1046
<211>  2072
<212>  DNA
<213>  Homo sapiens

<400>  1046
cgccgtgccc gcggagagag cgcggcgcgg gaggccggcg gccggccggc tgcatggcgc     60

gctgcgagag gctgcgcgga gcggccctgc gcgacgtgct gggccgggcg cagggggtcc    120

tgttcgactg tgacggggtg ctgtggaacg gcgagcgcgc cgtgccgggc gccccggagc    180

tgctggagcg gctggcgcgg gccggcaagg cggctctgtt tgtgagcaac aacagccggc    240

gcgcgcggcc cgagctggcc ctgcgcttcg cgcgcctcgg cttcgggggg ctgcgcgccg    300

agcagctctt cagctccgcg ctgtgcgccg cgcgcctgct gcgccagcgc ctgcccgggc    360

ctccggacgc gccgggcgcc gtgttcgtgc tgggcggcga ggggctgcgc gccgagctgc    420

gcgccgcggg gctgcgcctg gccggggacc cgagcgcggg ggacggcgcg gccccgcgcg    480

tgcgcgccgt gcttgtgggc tacgacgagc acttctcctt cgccaagctg agggaggcgt    540

gcgcgcacct gcgcgacccc gagtgcctac tcgtggccac cgaccgtgac ccatggcacc    600

cgctgagcga cggcagccgg acccctggca ccgggagcct ggccgctgca gtggagacag    660

cctcgggacg ccaggccctg gtggtgggca agcccagccc ctacatgttc gagtgcatca    720

cggagaactt cagcatcgac cccgcacgca cgcttatggt gggtgaccgc ctggagaccg    780

acatcctctt tggccaccgc tgcggcatga ccactgtgct cacgctcaca ggagtctccc    840

gcctagaaga ggcccaggcc tacctagcgg ccggccagca cgacctcgtg ccccattact    900

atgtggagag catcgcagac ttgacagagg ggttggagga ctgagcccac tgcacctgca    960

gccacaggcc cacccctccc cactccctga tcccgtaggt ggaggcgatg ggtcacgagc   1020

catgttaagc acaaccggct ccttggtcca gttctgcacc ggggtggggc tgggacccgg   1080

ggaaggtttg agggcccttg caaccccctc ccagcagtgg ctgggcactc tttgctgccc   1140

cagaagctgg tcccctatgg attcatcttg gcctgaccca gccaggtggc cttatttctt   1200

ccctgtcacc tcccctcctt gaaatctggg ccctggtgcc tgctgaagat tccctctatc   1260

cctgagtact tagtcttctc ccccttccct ggggcttcta gagctctctc tgcccctcag   1320

gtcctggccc ttgggtcctt gtcaaccaga ggtctaggga accacaaccc ttattgtcct   1380

gggtggacca atccaaaggc taagtgatag tgactcatca atgttgggtc ctgtggggta   1440

ccagtttagg ttcctaagta atagtgaccc tttcacgtcc tggagcccga gtggaccaat   1500

cggaagccta agtgacgatg accctcgcat gtcctaggtc cctgggtgga cccatcagga   1560

ccccaagtga tagtgaccca gtggtctttt agatcctcag tagaacagtc cagaagcctg   1620

agagacagtg gccccttgat aatctgggtc tcacgggacc agctaggggt ccaggtttca   1680

gtcagtaaat aagagtggtc cacgtcctaa agacacctct cctttacaaa gacttgtgat   1740

gctctggggc ttctgtggcc aagccccacc ctttcctggt catggtaccc gtacagcgtt   1800

gatggccaca gctcgaaggg gggctttcgt gtccccctgt gcggtcagtg ttttcagtac   1860

cacctctctc ccgtgcccac ttggctattt acttatttat ttattgtgtg ccagtgatgg   1920

tgggtggggg ctgggccttc cccgccacct ccacccctgt tgtgacctgt ccttccgtac   1980

ttaataaagt gcgcgtggga gtgttaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa                                 2072


<210>  1047
<211>  14895
<212>  DNA
<213>  Homo sapiens

<400>  1047
gtggcccgcg gcatggagcg ggcgtgattc atcagcatcc gcgccggggc ggcatggggg     60

cgcgcgcggc ggccgcctag gcgcccaggg ccaggcagcg gcggcttccc cggcccggct    120

cgcccgcgct tctctccctg tgggcggcgg cccggcgcct ggaaggtcaa gatggaagaa    180

atcctgagga agctgcagaa ggaggcgtcc gggagcaagt acaaagccat caaggagagc    240

tgcacctggg ccctggaaac tctaggtggt ctggatacca ttgtcaagat ccctccacat    300

gtactgaggg agaaatgcct gctgcctctc cagttggctt tggaatccaa gaatgtgaag    360

ctggcccaac atgctttggc agggatgcag aagcttctgt cggaagagag gtttgtatcc    420

atggaaacag attctgatga gaagcagctg ctcaatcaga tactgaatgc cgtgaaagtg    480

acgccttcgc tcaacgagga cctgcaggtg gaagtgatga aggttttact atgcatcacc    540

tacacgccaa catttgatct gaatgggagt gccgtgctga agatcgcgga ggtgtgcatt    600

gagacgtaca taagcagctg tcaccagcgt agcataaaca ctgctgtgcg ggcaactctc    660

agtcaaatgc tgagtgactt gactttacag ttacgacaga ggcaggagaa tacgataatt    720

gaaaacccag atgtcccaca ggatttcggg aatcaagggt caacagtaga gtccctctgt    780

gatgatgttg tctctgtact caccgtcctg tgtgagaagc tgcaagccgc cataaatgac    840

agccagcagc tgcagcttct ctacctggag tgcatcctgt ctgtgctcag cagctcctcc    900

tcctccatgc acctgcacag gcgcttcacg gacctgatct ggaaaaacct ctgccctgct    960

ctcatcgtga tcttggggaa tccaattcat gacaaaacca tcacctctgc tcacaccagc   1020

agcaccagta ccagcctgga gtcggactct gcgtctccgg gagtgtctga ccacggccga   1080

ggatcaggct gctcctgcac tgcgccggcc ctgagcggac ctgtggctcg gactatctat   1140

tacatcgcag ccgagctggt ccggctggtg gggtctgtgg actccatgaa gcccgtgctc   1200

cagtccctct accaccgagt gctgctctac cccccacccc agcaccgggt ggaagccatc   1260

aaaataatga aagagatact tgggagccca cagcgtctct gtgacttggc aggacccagc   1320

tccactgaat cagagtccag aaaaagatca atttcaaaaa gaaagtctca tctggatctc   1380

ctcaaactca tcatggatgg catgaccgaa gcatgcatca agggtggcat cgaagcttgc   1440

tatgcagccg tgtcctgtgt ctgcaccttg ctgggtgccc tggatgagct cagccagggg   1500

aagggcttga gcgaaggtca ggtgcaactg ctgcttctgc gccttgagga gctgaaggat   1560

ggggctgagt ggagccgaga ttccatggag atcaatgagg ctgacttccg ctggcagcgg   1620

cgagtgctgt cctcagaaca cacgccgtgg gagtcaggga acgagaggag ccttgacatc   1680

agcatcagtg tcaccacaga cacaggccag accactctcg agggagagtt gggtcagact   1740

acacccgagg accattcggg aaaccacaag aacagtctca agtcgccagc catcccagag   1800

ggtaaggaga cgctgagcaa agtattggaa acagaggcgg tagaccagcc agatgtcgtg   1860

cagagaagcc acacggtccc ttaccctgac ataactaact tcctgtcagt agactgcagg   1920

acaaggtcct atggatctag gtatagtgag agcaatttta gcgttgatga ccaagacctt   1980

tctaggacag agtttgattc ctgtgatcag tactctatgg cagcagaaaa ggactcgggc   2040

aggtccgacg tgtcagacat tgggtcggac aactgttcac tagccgatga agagcagaca   2100

ccccgggact gcctaggcca ccggtccctg cgaactgccg ccctgtctct aaaactgctg   2160

aagaaccagg aggcggatca gcacagcgcc aggctgttca tacagtccct ggaaggcctc   2220

ctccctcggc tcctgtctct ctccaatgta gaggaggtgg acaccgctct gcagaacttt   2280

gcctctactt tctgctcagg catgatgcac tctcctggct ttgacgggaa tagcagcctc   2340

agcttccaga tgctgatgaa cgcagacagc ctctacacag ctgcacactg cgccctgctc   2400

ctcaacctga agctctccca cggtgactac tacaggaagc ggccgaccct ggcgccaggc   2460

gtgatgaagg acttcatgaa gcaggtgcag accagcggcg tgctgatggt cttctctcag   2520

gcctggattg aggagctcta ccatcaggtg ctcgacagga acatgcttgg agaggctggc   2580

tattggggca gcccagaaga taacagcctt cccctcatca caatgctgac cgatattgac   2640

ggcttagaga gcagtgccat tggtggccag ctgatggcct cggctgctac agagtctcct   2700

ttcgcccaga gcaggagaat tgatgactcc acagtggcag gcgtggcatt tgctcgctat   2760

attctggtgg gctgctggaa gaacttgatc gatactttat caaccccact gactggtcga   2820

atggcgggga gctccaaagg gctggccttc attctgggag ctgaaggcat caaagagcag   2880

aaccagaagg agcgggacgc catctgcatg agcctcgacg ggctgcggaa agccgcacgg   2940

ctgagctgcg ctctaggcgt tgctgctaac tgcgcctcag cccttgccca gatggcagct   3000

gcctcctgtg tccaagaaga aaaagaagag agggaggccc aagaacccag tgatgccatc   3060

acacaagtga aactaaaagt ggagcagaaa ctggagcaga ttgggaaggt gcagggggtg   3120

tggctgcaca ctgcccacgt cttgtgcatg gaggccatcc tcagcgtagg cctggagatg   3180

ggaagccaca acccggactg ctggccacac gtgttcaggg tgtgtgaata cgtgggcacc   3240

ctggagcaca accacttcag cgatggtgcc tcgcagcccc ctctgaccat cagccagccc   3300

cagaaggcca ctggaagcgc tggcctcctt ggggaccccg agtgtgaggg ctcgcccccc   3360

gagcacagcc cggagcaggg gcgctccctg agcacggccc ctgtcgtcca gcccctgtcc   3420

atccaggacc tcgtccggga aggcagccgg ggtcgggcct ccgacttccg cggcgggagc   3480

ctcatgagcg ggagcagcgc ggccaaggtg gtgctcaccc tctccacgca agccgacagg   3540

ctctttgaag atgctacgga taagttgaac ctcatggcct tgggaggttt tctttaccag   3600

ctgaagaaag catcgcagtc tcagcttttc cattctgtta cagatacagt tgattactct   3660

ctggcaatgc caggagaagt taaatccact caagaccgaa aaagcgccct ccacctgttc   3720

cgcctgggga atgccatgct gaggattgtg cggagcaaag cacggcccct gctccacgtg   3780

atgcgctgct ggagccttgt ggccccacac ctggtggagg ctgcttgcca taaggaaaga   3840

catgtgtctc agaaggctgt ttccttcatc catgacatac tgacagaagt cctcactgac   3900

tggaatgagc cacctcattt tcacttcaat gaagcactct tccgaccttt cgagcgcatt   3960

atgcagctgg aattgtgtga tgaggacgtc caagaccagg ttgtcacatc cattggtgag   4020

ctggttgaag tgtgttccac gcagatccag tcgggatgga gacccttgtt cagtgccctg   4080

gaaacagtgc atggcgggaa caagtcagag atgaaggagt acctggttgg tgactactcc   4140

atgggaaaag gccaagctcc agtgtttgat gtatttgaag cttttctcaa tactgacaac   4200

atccaggtct ttgctaatgc agccactagc tacatcatgt gccttatgaa gtttgtcaaa   4260

ggactggggg aggtggactg taaagagatt ggagactgtg ccccagcacc cggagccccg   4320

tccacagacc tgtgcctccc ggccctggat tacctcaggc gctgctctca gttattggcc   4380

aaaatctaca aaatgccctt gaagccaata ttccttagtg ggagacttgc cggcttgcct   4440

cgaagacttc aggaacagtc agccagcagt gaggatggaa ttgaatcagt cctgtctgat   4500

tttgatgatg acaccggtct gatagaagtc tggataatcc tgctggagca gctgacagcg   4560

gctgtgtcca attgtccacg gcagcaccaa ccaccaactc tggatttact ctttgagctg   4620

ttgagagatg tgacgaaaac accaggacca gggtttggta tctatgcagt ggttcacctc   4680

ctccttcctg tgatgtccgt ttggctccgc cggagccata aagaccattc ctactgggat   4740

atggcctctg ccaatttcaa gcacgctatt ggtctgtcct gtgagctggt ggtggagcac   4800

attcaaagct ttctacattc agatatcagg tacgagagca tgatcaatac catgctgaag   4860

gacctctttg agttgctggt cgcctgtgtg gccaagccca ctgaaaccat ctccagagtg   4920

ggctgctcct gtattagata cgtccttgtg acagcgggcc ctgtgttcac tgaggagatg   4980

tggaggcttg cctgctgtgc cctgcaagat gcgttctctg ccacactcaa gccagtgaag   5040

gacctgctgg gctgcttcca cagcggcacg gagagcttca gcggggaagg ctgccaggtg   5100

cgagtggcgg ccccgtcctc ctccccaagt gccgaggccg agtactggcg catccgagcc   5160

atggcccagc aggtgtttat gctggacacc cagtgctcac caaagacacc aaacaacttt   5220

gaccacgctc agtcctgcca gctcattatt gagctgcctc ctgatgaaaa accaaatgga   5280

cacaccaaga aaagcgtgtc tttcagggaa attgtggtga gcctgctgtc tcatcaggtg   5340

ttactccaga acttatatga catcttgtta gaagagtttg tcaaaggccc ctctcctgga   5400

gaggaaaaga cgatacaagt gccagaagcc aagctggctg gcttcctcag atacatctct   5460

atgcagaact tggcagtcat attcgacctg ctgctggact cttataggac tgccagggag   5520

tttgacacca gccccgggct gaagtgcctg ctgaagaaag tgtctggcat cgggggcgcc   5580

gccaacctct accgccagtc tgcgatgagc tttaacattt atttccacgc cctggtgtgt   5640

gctgttctca ccaatcaaga aaccatcacg gccgagcaag tgaagaaggt cctttttgag   5700

gacgacgaga gaagcacgga ttcttcccag cagtgttcat ctgaggatga agacatcttt   5760

gaggaaaccg cccaggtcag ccccccgaga ggcaaggaga agagacagtg gcgggcacgg   5820

atgcccttgc tcagcgtcca gcctgtcagc aacgcagatt gggtgtggct ggtcaagagg   5880

ctgcacaagc tgtgcatgga actgtgcaac aactacatcc agatgcactt ggacctggag   5940

aactgtatgg aggagcctcc catcttcaag ggcgacccgt tcttcatcct gccctccttc   6000

cagtccgagt catccacccc atccaccggg ggcttctctg ggaaagaaac cccttccgag   6060

gatgacagaa gccagtcccg ggagcacatg ggcgagtccc tgagcctgaa ggccggtggt   6120

ggggacctgc tgctgccccc cagccccaaa gtggagaaga aggatcccag ccggaagaag   6180

gagtggtggg agaatgcggg gaacaaaatc tacaccatgg cagccgacaa gaccatttca   6240

aagttgatga ccgaatacaa aaagaggaaa cagcagcaca acctgtccgc gttccccaaa   6300

gaggtcaaag tggagaagaa aggagagcca ctgggtccca ggggccagga ctccccgctg   6360

cttcagcgtc cccagcactt gatggaccaa gggcaaatgc ggcattcctt cagcgcaggc   6420

cccgagctgc tgcgacagga caagaggccc cgctcaggct ccaccgggag ctccctcagt   6480

gtctcggtga gagacgcaga agcacagatc caggcatgga ccaacatggt gctaacagtt   6540

ctcaatcaga ttcagattct cccagaccag accttcacgg ccctccagcc cgcagtgttc   6600

ccgtgcatca gtcagctgac ctgtcacgtg accgacatca gagttcgcca ggctgtgagg   6660

gagtggctgg gcagggtggg ccgtgtctat gacatcattg tgtagccgac tcctgttcta   6720

ctctcccacc aaataacagt agtgagggtt agagtcctgc caatacagct gttgcatttt   6780

ccccaccact agccccactt aaactactac tactgtctca gagaacagtg tttcctaatg   6840

taaaaagcct ttccaaccac tgatcagcat tggggccata ctaaggtttg tatctagatg   6900

acacaaacga tattctgatt ttgcacatta ttatagaaga atctataatc cttgatatgt   6960

ttctaactct tgaagtatat ttcccagtgc ttttgcttac agtgttgtcc ccaaatgggt   7020

cattttcaag gattactcat ttgaaaacac tatattgatc catttgatcc atcatttaaa   7080

aaataaatac aattcctaag gcaatatctg ctggtaagtc aagctgataa acactcagac   7140

atctagtacc agggattatt aattggagga agatttatgg ttatgggtct ggctgggaag   7200

aagacaacta taaatacata ttcttgggtg tcataatcaa gaaagaggtg acttctgttg   7260

taaaataatc cagaacactt caaaattatt cctaaatcat taagattttc aggtattcac   7320

caatttcccc atgtaaggta ctgtgttgta cctttatttc tgtatttcta aaagaagaaa   7380

gttctttcct agcagggttt gaagtctgtg gcttatcagc ctgtgacaca gagtacccag   7440

tgaaagtggc tggtacgtag attgtcaaga gacataagac cgaccagcca ccctggctgt   7500

tcttgtggtg tttgtttcca tccccaaggc aaacaaggaa aggaaaggaa agaagaaaag   7560

gtgccttagt cctttgttgc acttccattt ccatgcccca caattgtctg aacataaggt   7620

atagcatttg gtttttaaga aaacaaaaca ttaagacgca actcatttta tatcaacacg   7680

cttggaggaa agggactcag ggaagggagc agggagtgtg gggtggggat ggattatgat   7740

gaaatcattt tcaatcttaa aatataatac aacaatcttg caaaattatg gtgtcagtta   7800

cacaagctct agtctcaaaa tgaaagtaat ggagaaagac actgaaattt agaaaatttt   7860

gtcgatttaa aatatttctc ctatctacca agtaaagtta ccctatgttt gatgtctttg   7920

cattcagacc aatatttcag gtggatattt ctaagtatta ctagaaaata cgtttgaaag   7980

ctttatctta ttatttacag tatttttata tttcttacat tatcctaatg attgaaaact   8040

cctcaatcaa gcttacttac acacattcta cagagttatt taaggcatac attataatct   8100

cccagcccca ttcataatga ataagtcacc ctttaaatat aagacacaaa ttctacagta   8160

ttgaaataag gatttaaagg ggtatttgta aactttgccc tccttgagaa atatggaact   8220

accttagagg ttaagaggaa ggcagtgttc tgacttcttt aggtgatctg aaaaaaacac   8280

ccttatcatc cagtgtacca tctagagatc accacagaat ccattttttt cccagttcca   8340

caaaacactc tgtttgcctt cagtttttac tcactagaca ataattcaag tttagaaaca   8400

ggtaatcagc tatttgatct taaaaggcaa tgaattgttg ggatatcagt gaactatgtt   8460

gtatactttt gaatttttac attttataaa tggaattgaa agttggataa ctgctttttt   8520

taaattttcc aacagaagta acaccacagt tgctttgttt ctttttatag cttacctgag   8580

gttcagttct tctttgtgaa cctgtgagta ctccacagtt tactggggga aaaggcttca   8640

gtaaagcaga ggctagaatt acagtattta tacatagcaa cttttcataa agtagaaaaa   8700

ttcaaaggaa gctgtctcaa tttgagaata ccagctgggc acggtggctc acgcctgtaa   8760

tcccagcact tactttggga ggccaaggtg ggcagataac ctgcggtcag gagtttgaga   8820

ccaggctgga caacatggtg aaacctcgtc tctactaaaa atacaaaaat tagccaggtg   8880

tggtaggatg cacctgtaat cccagctact taggaggccg agacaggaga atcgctcgaa   8940

cccaggaggc ggacgttgca gtgagccaag attgcaccat tgcactccag actgggtgac   9000

aagagtgaaa ctccatctaa aaaaaaaaaa aaaaaaaagt gaatactgta tcccaaagta   9060

tgttagttgt ttgtttggaa atcagcattc tccccgatgc tctattatgg gatccaaaat   9120

tcttgaacat aagtttaccc tgtactgtgt ccaaacactg ttctagttct agcctgatta   9180

tgggtcccaa gaataaaagg atgagtaggt gtacagagct cttgacctac aattttttaa   9240

gagtgttttg gtaccttccc attgtcttct ctataactca gtcctaacat actctgcact   9300

cgagttacca gccatccaca ctgacatcag atttcaacca gaaccatcac tgagtgacag   9360

cagtacttct cagaggtatt tgcagcttga tgcaaagtag tctctaatga gtaggcattc   9420

aggtggttct tcccagcagg tggagaagaa agggaggaga tgaagaacac tgagagggga   9480

gtggcacctt cccaggctgc ccagctcagt ctcttgccct gttcctgtga ctcagctgcc   9540

cactccccca actttgtttc cctccctccc agtctctgaa agtgtcaggt gtttctctcc   9600

tcacagtctc ttttgcagca acagtaagac aaaattcaag gcagcctttt aaagttacga   9660

acagttatta gcatgtattt acagacctaa gcagaatgag agtttataca ttgtttttag   9720

ttgcctgtat ttatagccaa aagtatatta ccttaaagtt gagatctttc tcttcttttc   9780

ctaaattttg gtaaagtgtg cttcatgaaa caaacatctg gaaaactcca agtataagag   9840

accctggact gatgatggcc cagccaagta tatggaggga cagagttctc tctgtcatta   9900

atgaggacat cggttttcac aattgaacct catgcactgt ccacagcatc tcacctagct   9960

cctgtatctc ctgatctgct tttaaaaata gttagttagg ctgccttttt acaccacctt  10020

ctctctctcc ccttgtggta attttccagc cttccccata gatataaaac tagaacacct  10080

ttatgatttg gggtctatgt aatgactgac cgataagaac ccaggcagat gctaacatac  10140

ttaacagctc gcattaaaat actttaaatc aggcgtgatg gctcattcct gtaatctcaa  10200

gcactttggg aggctaaggt gggtggatct cttgaggtca ggagttcgag accaacctgg  10260

ccaacgtggt gaaaccccgt ctctactaaa aatacaaaat tagccgggca tggtggcagc  10320

tgcctgtaat cccagctact cgggaagctg aggcaggaga attgcttgaa cctgggaggt  10380

ggggattgca gtcagccaag attgttctgc agcatgggtg acaaagtgag acttcgtctc  10440

aagtaaataa aactaaaatt tttaaatcaa acatgacaaa aatgttaata taattcagaa  10500

gtaccttgaa attgaaacat atttgtgcaa tgatcattag gctttttgtc cttgttgttt  10560

taaaatgagg cttatacaga gtgagttgag agtcaagtag ccttcgctgt gagacggtaa  10620

tgcagttata taatagatac ccttgacttt gccagattca tcacaatact gcttatacag  10680

gaaagttttc tcagaaagga aaatccatta gtatcagtcc catcaagcca aacagaatga  10740

agacctttga tagtaatagc aagaggttac aaatagcagg gaggaggcga gtagtgaatg  10800

tcactgtgat tgcaaaccct tacctgtatt atcacacgta gtcctcacaa caaccttgtg  10860

agacaagtgt tgtgttcctc attttttcag aggggaacac agacccagag aggttaagaa  10920

atttgcccaa gataacaagt aaaaggcaaa gttggttgca aaagaggtgt ttctgaattc  10980

aagggccata ctctctctct gacaacatgc tctaagtcca tagagtaagc actctagtat  11040

gaaaaaaagt ttcaaggaac gaggccatga aaatgagact atttgacatc tcagatctgt  11100

ctgggatgtt atggaggttt ttaaaaataa agttgaaaaa agaaaatgaa tcatgtttat  11160

acataaaaaa atcacatgta acacatttca agtgtttgaa aataaaacca aaatctaaac  11220

tttagtcttc aagcagacat tcagtgttac tttagaaaac tcactgaatt aggtggaaat  11280

gatggaataa tactattcat ggccagctat taacacagaa gaacatggca gtgtgtgtct  11340

ggaacggcat gcacaatttg taaacctttt tcaaatatca tttaatcaac tcagaataaa  11400

gtgccctgta gccaacagtg cctctttact tgcttctctg ggaaatacat ggtactaaat  11460

tagtagcaca aagtttggga atatgcaaaa taatggataa ccatttttca aaatgtacat  11520

tctctgaaga ggaagcagct ggttggacag gatttcttga agagccaggt gctaagggca  11580

tcaggtcgac atccatagta accatgtgcc ataacatcta cacatttcca cttgttttac  11640

agacaaggta acaggcagaa ggaaaatcca gagtcttgca gtaagcagat gacaaaactt  11700

caatatgctt gggcaccact taggtgaccc cagggagatt tagtgtggcc ttaggaaagc  11760

aaaagagcac tttttattgg aaatatgagc ttgtcactgg gaaagatttg taaaattgat  11820

caagaacttg atttataatt atgcctcaaa aaaaaaagtt ctcatttagt agtggagcaa  11880

tctagaaaac ataccttttt tgtttgtttg gaagatcctc tttccctggc tgtattgtag  11940

tgtttgctat ttgatgtgga aataactaat aacttaagat tttggaacag aacacccttt  12000

agatttccaa aacacaattc ttatttcagg gaagacagac caaaaatatc tcctgagatc  12060

attggtttct ttataaattg tggtaccact ccatcattga agagaaacca ctaccacacc  12120

actagcacca tacagaacct tttctctgta tctttgtaca atactacaaa ggggtaccag  12180

ggaggagaga gtggctgacc actttagtga caaaacagca ctccactgct ggtgaatccc  12240

atctaattat ggtccttcca cccttttcaa ccaccaacaa ctgttcgtac tgttaattcc  12300

tatcctgaag gtttaaccag tggttgtcta gtatcttctg tctttagaac agtggttctc  12360

aaactttagt acacatcagc atcacctgga gggccttttt ttaaaataag acacagattg  12420

ctgggctcat ggtcagagtt cccagttaag taaatcagga aatttgtatt tctaacaagt  12480

ttataggtga ggccaatact gctgttttgg gaactatgct ttgagaacca ctgccttgaa  12540

aaaatttcca acttctacct ttaagatcag cctgacttat caaacgctag agaaaaactg  12600

aatctaccct tgggcagatg acttgggatt ggattctata cagcagtctt gctcaatctt  12660

cccagtttcc agttttatta taccaacaat tggtttttac aagctagaag acaatgaatg  12720

tataagttct atggaacagt gagataaatc taagcttctt gtctttgtat ttagaaacat  12780

tgattctatg gatgatcatt tgtatcatgt tgaccctttg acttgtactg aaggtgattt  12840

taaatttaag tatgtagtgt ttgaatttct tccatccatg tcgttttaat gagatgtttc  12900

catgtcagct cctttacagc cttggctcct ggcttacaga tttttgaata gttgtttgct  12960

tgccagttgt tttacatctt tcattggcca ccaaaatatt agccatttga gatgagatga  13020

gactacttgt tgtaccttca tctttcattt aattttctgg cgtaaattaa cattttaatt  13080

tcatatatat ctgtaaagag tctacccaaa ggcttcacgg aaatttgcaa aatgaactaa  13140

ttccctttta agcagcaggt gtgcctgttt ttgacttttc agtaaatatg ttgtttgtgc  13200

acatatctac atggtggaga ccatattcat tatttcatct tccaaataat gggaaaaata  13260

taaaagtgaa tcagtgtgct ttgggaattc agtgaaatca tgttaactca tatagagggg  13320

gccttagttt atctcttctt tactgaatta attagttttg gaaattcttt taccattaaa  13380

aaaaattaag gaccatacag agaatgattt aagaaaaaac aagtcactta aaaatcatca  13440

cctatttata aactgtatta attacacata atgcttattg attcaatgag gtttctctaa  13500

agacttctgc ttaataaata tgctgacttc atttaaatta gtttagacta ttgtaggaat  13560

ggaaggaaat gattatattt actagaatta gtgagatcag aaagcatatc agaatgttga  13620

tgatatcaag gagacaatct acagagtttt tgcctctgtg gatggaaata agggtgtttt  13680

tttttggttt tttttttact ttagtttccc ataatttttg gaaattatgt gtgcatttag  13740

ttcttttagt aacactgatt ttaaaattaa atttcaaaag tcaatctcta agagtaattt  13800

atttttgttt taccaaccag tgccaaaaag gagaggaggg aatccaaaag ccaatctttt  13860

gaaccaatgt gtaaaagatt atgttttttc ttaaagttag ggaggctcgg gccctgacac  13920

tgccagcccc agtgagcatc cctggctacc tcgggattat gtgcaagctg ctttgtccta  13980

catttctttc atctggttct tattgggagt gcttctctct aataaaaatt gatttcccac  14040

aaaataggca aagctgaaca aagatgaatg cttttgataa gttgggtttc acttcagttg  14100

aaacaatgtg atagaatatc caggtgtggc atgatggggc aggaggaggt gcctagaggg  14160

aaaagttatt tttgtttctt agtgttgtgt tgtggggatg ggacagataa gaataagatg  14220

tttattgccc taatcatgct aagagactat tattcaatat gcttttcccg cttttctaag  14280

aggaataaac ttagacaaat tacattataa acagttcccc tactactatc tcccactcta  14340

gataaagcca gtgggtggta tgggtccttt tattccttat agtattatgc caaagaatca  14400

acttattttc attgaagatt ataaataaat gaagcttgtt atagccataa tgatttgagt  14460

cagtatacca ttttacctat aaaatgcaaa attcatcctt gcaaccccat tcaccaggag  14520

ccttgaagca ttttgtttac tccaaaggcc ttgtcaagga agcataattt tttgttttgc  14580

cttcttattt agtcagtttg gtcatattta cttaaaaaaa caaactgaaa atcacactcc  14640

tttatatgtt gatataactg attttataga atctgtctgt tctttgttta acaggtctct  14700

gtaagcaagc ttgcaagtgt attttgtgta cattttatct gaggtggaaa tgaaaattct  14760

aaagagaaaa tattttaaaa gatattgtat ttatgttgct tgtgttgtag aataaagatt  14820

caaatgcatt aaaaatctgg tacatgaaac aattgtgttt actgaataaa tatatataaa  14880

taaaaaaaaa aaaaa                                                   14895


<210>  1048
<211>  4221
<212>  DNA
<213>  Homo sapiens

<400>  1048
agcctcttct tcactggctc ccgccctctt tcagtcttgg ccctctcctc cctgtccccc     60

cggactaaat acgcacaccc cctctttctt tctgtgcaag caagagggtc ctggaacagc    120

gggttctgag gaggctggga ggcagggctg agaggtggcc gagagagagg agtcgcagag    180

ccgccagagt gagtcaggca cctccactgg gattacagat cccagagcct cgaggagctg    240

gaagacatgt ccccttcttt cctctgcacc ccagcccgca gccagccccc caccccccag    300

cccctccttt ctccctgctc tcaggaccca cagtgaccac tctaggctcc tatgaggctt    360

ccgagggctg tgagaggaag aagggccaac gctgggggtc cctggaacga cgggggatgc    420

aagctatgga gggggaggtg ttactcccag ctctctatga ggaggaagag gaagaggaag    480

aggaggaaga agaggtggaa gaagaagaag aacaagtgca gaaaggtggc agtgttggct    540

ctctgtcagt caacaagcac cggggactga gcctcacgga gacagagctg gaggagctgc    600

gggctcaggt gctgcagctg gtggcagaac tggaggagac ccgggaactg gcagggcagc    660

atgaggatga ctccttggag ctacaggggc tcctggagga tgaacggcta gccagcgccc    720

agcaggcaga ggtgttcacc aagcagatcc agcagctcca aggtgagctg cgttctctac    780

gggaggagat ttccctgtta gagcatgaga aagaaagcga acttaaggaa atagaacagg    840

aattgcattt ggcccaggct gagatccaga gtctgcggca agcagcagag gattccgcaa    900

ctgaacatga gagtgacata gcatccctgc aggaggatct ctgccggatg cagaatgaac    960

ttgaagacat ggaacgcatt cggggagatt atgagatgga gatcgcctcc ctccgtgcag   1020

aaatggaaat gaagagctct gaaccatccg gtagtttagg tctctcagat tactctgggt   1080

tacaagaaga actgcaggag ctgcgggaac gctaccattt cctgaatgag gaataccggg   1140

ccctgcagga gagcaacagc agcctcacgg ggcagcttgc agatctggag agtgagagga   1200

cacagagagc aacagagaga tggctgcagt cccaaacact gagtatgacg tcagcagagt   1260

ctcagacttc agaaatggat ttcttagagc ctgatcctga aatgcagttg ttacggcagc   1320

agctacggga tgctgaagag cagatgcatg gcatgaagaa caagtgtcag gaattgtgtt   1380

gtgagttgga agagctacag catcatcgcc aggtcagtga ggaggagcag aggcggctgc   1440

agagggagct caagtgtgct cagaatgagg tgcttcggtt tcagacctcc cacagtgtca   1500

cccagaatga ggagctgaag tccagactct gtaccctgca gaaaaaatat gatactagcc   1560

aggatgagca gaacgagctc ttgaagatgc agctgcaact tcagactgag ctccggcagc   1620

tcaaagtcat gaaatccaca cttgtagaaa accagagtga gaaggagtta ctgtgccggc   1680

tgcagaagct gcacctccag caccagaacg tcacatgtga gaaggaaaag ctgctggaac   1740

ggcagcagca gctgcaggag gagctgcagt gccatgaggc agagctgcag cacctcaggg   1800

atacggtggc ctccttcaaa gagagcaatg agaaggacac agagacgcac gctcagcttc   1860

aggagatgaa gcagctgtac caggccagca aggacgagct ggagcggcag aagcacatgt   1920

atgaccagct ggagcaggac ctcctgctct gccagctgga gctgaaagag ctcaaggcct   1980

cccaccccat tccggaggac aaaggaaagt gtgctaataa gtgtgacaca ctgctgtcca   2040

gactgacaga attgcaggaa aagtacaagg ccagccagaa ggagatgggg cagctgcaga   2100

tggagcagtg tgagctcctg gaggatcaga ggaggatgca ggaggagcag ggccagctgc   2160

aggaagagct gcacaggctc acactgccac tgccaaagag tggcctctta ctcaagagtc   2220

aggagctact caccaagtta gaagacctgt gtgagctgca gctgctctac caaggcatgc   2280

aggaggaaca gaagaagctg atacagaacc aagactgtgt attaaaagaa caattagaga   2340

tccacgaaga gctgcgacgt ttcaaagagt ctcatttcca ggaagtgttg gagaatcccg   2400

atgattccaa attggctaag tcctccaaat gtaatcgaaa caagcaatcc aagctgctca   2460

tggagcagat gcaggccctg caggtgatgt atgacgccgg tcaggcgaag caggagctct   2520

tgcagcaaga gcaagggagg ctcctagagg agcggaagag gctgcaggca gacttgcagc   2580

tctgcctgga agaaatgcag ctgcttcaag tccagtcccc ttctataaaa atgagccttg   2640

agtcctacgg gaagagctat ggtagcatgg tccccagcaa tgagaactgt cgcaagactt   2700

atgataccac tgtggatgac aatgagagct attacaagag ttacaccagc acccagacca   2760

gcagcaagag ctttctcaag agctatgaca gcagcaccag tgccagtgag gcctatggga   2820

agagttactg cactaccagc aacagcagca ttacctataa gaagagttac ggcagcacca   2880

gtagctctga cacctgccag aagagttttg tcagcagctg cactgacgag gaacctgctg   2940

agcctgaaga catggagcgc tttgaggaaa tggttgtgaa agtgctgatc aagctgcagg   3000

cggtgcaggc catgtaccag ataagccagg aggaacacag ccagctgcaa gagcagatgg   3060

aaaagttact ggccaagcag aaagacctga aggaagagct ggatgcctgt gaaagggagt   3120

tcaaggagtg catggaatgc cttgaaaagc ccatggcccc ccagaacgac aagaatgaga   3180

tcaaagaact gcagaccaag ctgcgggagc tgcagctgca ataccaggct agcatggatg   3240

agcaggggcg gcttctggta gtgcaggagc agctggaggg gcagctgcag tgctgccagg   3300

aggagctccg ccagctcagg gagaagaggc cttctgttgt caaagaagcc cgggggaaga   3360

atgctaataa gaacatgaac aagaatgcca atggggttaa aatgaaaaag gtgaccaagc   3420

catgctcgga tacttctgag agcgaccttg agaccagaaa gagtctggag gtagtgctgt   3480

actacaaggc cagccagagg aaattagatg gactagcaaa agaggaggaa aagaaagagg   3540

agatggagga ggaaaaaaag gaagtgaaag aggaagcaaa ggagcagtgt ggggatgagc   3600

tagttgctga gccagcagat cctgaggaag ctaaatccac agaagatcag gaggaaaatg   3660

aagaggacaa agaggaagag gagaaggaag aagacagtga agaggaggag gatgacgccg   3720

actcttccct tgaaagtccc gaagaaaata accccctcag actttccgag agcaaaaagt   3780

catcccctac ccccaatccc cccatcttct ccttgcctct tgtaggcctg gtggtcatct   3840

cggctttgct ctggtgctgg tgggctgaga cgtcgtccta atgcagaaca tgtttgggtt   3900

gtggaagcct atggtattct tggctattgc agctgtggct ctgtatgtgt tacccaacat   3960

gcgacagcag gagtcagagt tctgcctcat ggagtgatgg cagaccttgg ccagcgcgag   4020

ggcagatccc cagtggccac caccctcagc tttgggcagg acacactgtg ccagaaccct   4080

ccccatatgt tccatgtgtc cccatctcct cagcctcagt cacccaggct gaaaaggctt   4140

gtggggagcg gctgacttcc atctcctgcc ttgtgtaaga acctgagttc cttgtaatta   4200

aatatcaact gaattacatg a                                             4221


<210>  1049
<211>  7817
<212>  DNA
<213>  Homo sapiens

<400>  1049
gaaagtgacc ggaagtaacc gccgggccaa gatggctgca gaggaagggg tcgcgagtgc     60

tgcttccgcc ggcggtagct ggggcaccgc ggccatgggg cgggttctac cgatgctgtt    120

ggtgccagtc cccgccgagg cgatggggca gctcggctcc cgggcgcagc tgcgcacaca    180

gccggaggct ctggggagcc tgacggctgc gggcagcctc caagtgcttt ctttgacgcc    240

tggcagccgg ggcgggggtc gctgctgcct ggagggcccc ttctggcact ttctatggga    300

ggattctcgt aacagcagca caccaactga aaagcccaaa ctgctcgctc ttggtgaaaa    360

ttatgaactg cttatctatg aatttaattt gaaagatgga agatgtgatg caaccatttt    420

gtatagctgt agtagggagg cattgcaaaa gctcattgac gatcaagata tcagtatttc    480

cttattgtct ttgagaatcc tgtcatttca caataacaca tcattactgt tcatcaacaa    540

atgtgtcatc ctacatatta tatttcctga aagagatgct gcaattagag tactcaactg    600

tttcacactt cccttgcctg cacaggcagt ggacatgatt attgacacgc agctctgcag    660

aggaattctt tttgttttga gtagtttagg ctggatctac atttttgatg ttgtggatgg    720

tacatatgta gctcatgtgg atttagcact tcacaaagaa gacatgtgta atgagcagca    780

acaggagcca gccaagattt cttcatttac ttcactgaaa gtttctcaag acctcgatgt    840

tgcagtgatt gtcagctcct ccaactccgc agttgctctt aacttaaatt tgtatttcag    900

gcaacaccca ggacacctac tgtgtgaaag aatactagaa gatcttccta ttcaaggacc    960

taagggcgta gatgaagatg atcctgttaa ctctgcctac aacatgaaac tggccaagtt   1020

ttccttccaa attgataggt cttggaaagc ccagctatca tcattgaatg aaacaataaa   1080

gaactccaaa ctggaggttt cctgttgtgc tccatggttc caggatattt tgcatttgga   1140

gtcacctgaa tctggtaacc acagtacaag tgtgcagagc tgggccttca ttccacagga   1200

cataatgcat gggcaatata atgttctaca gaaagatcat gccaagacca gtgatccagg   1260

aagatcatgg aaaataatgc acatcagtga acaagaggaa cccatagagc ttaaatgtgt   1320

gtctgtgaca ggattcactg cactgtttac ttgggaagtg gaaaggatgg gctataccat   1380

taccctctgg gatttggaga cccagggcat gcagtgtttt tcccttggca caaagtgtat   1440

tcctgtagac agtagtggag accagcagct gtgctttgtt ttgacagaga atggactctc   1500

tctgattttg tttggtttga ctcaagaaga gtttttaaac agactcatga tccatggaag   1560

tgccagcact gtggacactc tttgtcatct caatggctgg ggaaggtgct caattcccat   1620

acatgcacta gaggccggga tagaaaatcg tcagctggac acagtaaatt tctttttgaa   1680

gagcaaggaa aatcttttta atccatcctc aaaatcttct gtatctgatc agtttgatca   1740

cttgtcatcc catttatatt taagaaatgt ggaagagctg ataccagcat tggatttact   1800

ttgctcggca attagagaaa gttattctga accccaaagc aaacactttt cagaacaatt   1860

gcttaatctt acactgtctt tccttaacaa ccaaataaag gagcttttca ttcacactga   1920

agaactagat gaacatctgc aaaaaggagt gaacattttg actagctaca ttaatgaact   1980

tcgaaccttc atgataaagt ttccttggaa gctaacagat gctatagatg aatatgatgt   2040

acatgaaaat gtccccaaag taaaggagag caatatatgg aagaaactca gctttgagga   2100

agttattgcc agcgccattt taaacaacaa aataccagag gcacagactt tcttcaggat   2160

tgatagtcat tctgctcaaa aacttgagga gcttattggc ataggcctaa atttggtctt   2220

tgacaattta aaaaagaaca atataaagga agcctctgaa cttttgaaga atatggggtt   2280

tgatgtaaaa ggccaattgc tcaagatctg cttctataca actaataaaa atatacgtga   2340

ctttttggtt gaaattttaa aagaaaaaaa ttatttttct gaaaaagaga aaagaactat   2400

agacttcgtg catcaagttg agaagcttta tttgggacat ttccaagaaa atatgcaaat   2460

ccagtcattt cccaggtact ggataaagga acaagatttt ttcaagcaca agtctgtttt   2520

ggactcattc ctgaaatatg attgtaaaga tgaatttaac aaacaggacc atagaattgt   2580

gttaaattgg gctctgtggt gggatcaact aacacaagaa tccatccttc tccccaggat   2640

aagtccagaa gaatacaaat catattcccc tgaagccctc tggagatacc tcacagctcg   2700

ccatgattgg ttaaacatta tcttatggat tggagaattt caaacccagc atagttatgc   2760

ttcacttcag cagaacaaat ggccccttct gactgttgat gttattaacc agaatacttc   2820

ctgtaacaac tacatgagga atgaaatttt agataagctg gccaggaatg gggttttttt   2880

ggcatctgaa ctggaagact ttgaatgctt cctcctaaga ctgagccgta ttggaggtgt   2940

aatacaggat accctccctg ttcaaaacta caagaccaaa gaaggttggg atttccattc   3000

tcaattcatt ctctattgtt tggagcacag tctgcagcat cttctttatg tctaccttga   3060

ctgttacaaa cttagtcctg aaaattgtcc ctttttggaa aaaaaagagt tacatgaagc   3120

acacccttgg tttgaatttt tagttcagtg tcgacaagtt gccagtaact taacagatcc   3180

caaactgatc ttccaggcta gccttgcaaa tgctcagatt ttgattccca ccaatcaggc   3240

cagtgtaagc agtatgctat tggaaggaca taccctcctg gcccttgcta ctacaatgta   3300

ttctcctggg ggtgtcagtc aggttgttca gaatgaagaa aatgaaaact gtttgaagaa   3360

agtggatccc cagctattga agatggcatt aactccttac cccaagctaa aaactgctct   3420

cttcccacag tgcactcctc ctagtgtcct gccatctgat attacaatct accaccttat   3480

tcagtcatta tcaccctttg atcctagcag attgtttggc tggcagtctg ctaacacact   3540

agctatagga gatgcatgga gtcatctccc acatttctct agccctgacc tggttaataa   3600

atatgctata gtggaacgtc tgaattttgc ttattattta cataatgggc ggccatcatt   3660

tgcatttggt acttttctgg tccaggaatt aatcaagagc aagactccca agcagctgat   3720

ccagcaagta ggcaatgaag cctatgttat agggctctcc tccttccaca taccttcaat   3780

aggagctgca tgtgtttgtt tcttagaatt gcttggcctt gacagcctca agctcagagt   3840

tgatatgaaa gtggccaata taattttgag ctacaagtgc agaaatgaag atgctcagta   3900

cagctttatc agagagtctg tagccgaaaa actatctaaa ctagctgatg gtgaaaagac   3960

aaccacagaa gaattgcttg ttctcttaga agaaggtaca tggaacagca ttcagcaaca   4020

ggaaataaag aggttatcca gtgaatctag cagccaatgg gcattagtgg tgcagttctg   4080

caggctacac aatatgaaac taagcatatc ttaccttaga gaatgtgcca aagcaaatga   4140

ttggctgcag ttcattattc acagccaact ccacaactac cacccagcag aggtgaaatc   4200

ccttatccag tacttcagcc cagtcattca agaccactta aggctggctt ttgagaactt   4260

gccctcagtg cccacctcca aaatggacag cgatcaagtc tgcaataagt gcccccagga   4320

acttcaagga agcaaacaag agatgaccga tttatttgaa attctgctcc aatgctcaga   4380

ggagccagac tcctggcact ggcttctggt tgaagcagtg aaacaacagg cccctatcct   4440

cagtgttctg gcctcatgtc tccagggtgc cagtgccatt tcttgtctct gtgtttggat   4500

catcacttct gtggaggaca atgttgcaac tgaagcaatg ggacacattc aggactcaac   4560

agaggaccat acctggaacc ttgaggatct ttcagtcatc tggagaacat tattaacaag   4620

acaaaagagc aaaactctca tcagaggttt ccagcttttc tttaaggatt ccccgttact   4680

actggtgatg gagatgtatg aactgtgtat gttcttcagg aattataaag aagctgaagc   4740

taaacttctg gagtttcaga agagccttga aacgcttaac acagcagcca caaaggtcca   4800

ccctgtcatc cctgccatgt ggctggagga tcaggtgtgt ttccttttga agcttatgct   4860

acagcagtgt aagacccagt atgagctggg gaagctttta cagctctttg ttgaaagaga   4920

gcatctcttc tctgatggtc cagatgtgaa aaagctttgc atcctttgcc agattttgaa   4980

ggatacatcc atagccatta atcatacaat tattaccagc tacagcattg agaatcttca   5040

gcatgaatgt agatctattt tggaaagact gcagacagat ggacaattcg ctttggccag   5100

gagggtagca gaattagctg agttacctgt ggacaacttg gttattaaag agataacaca   5160

ggaaatgcag accctaaaac acattgaaca gtggtcacta aaacaagcaa gaattgactt   5220

ctggaaaaaa tgccatgaga attttaagaa aaattcaatt tcaagcaaag cagcttcttc   5280

ctttttctca acccaggccc atgtggcatg tgagcaccca actggatgga gcagcatgga   5340

ggagcgccat ctgctgctca ccttggcagg gcactggctt gcccaggagg acgtggtgcc   5400

cttggataag ctggaggagc tggagaagca gatctggctg tgccgcatca cccagcacac   5460

tcttggaaga aatcaggagg aaacagagcc cagattttct cgacagatct caactagtgg   5520

tgaactttcc tttgatagtt tagccagtga gttttccttc tccaagttgg ctgctctgaa   5580

cacatcaaaa tacttagaac ttaacagcct tccatccaaa gagacatgcg agaatagatt   5640

ggattggaaa gagcaggagt cactaaactt tttgattggg cgcctactgg atgatggctg   5700

tgtgcatgaa gcaagtagag tatgccggta ttttcatttt tataatccag atgtcgcctt   5760

ggtattgcac tgcagagcac tggcctcagg ggaagctagt atggaggatc tgcacccaga   5820

gatccatgct ctcctacaaa gtgctgagct gcttgaggaa gaagcacccg acattcccct   5880

aaggagagtc cacagcactt caagtctgga tagtcagaag tttgtgacag tgccctccag   5940

taatgaagtg gtaactaacc tggaagtgct gacaagcaaa tgcctccatg ggaagaacta   6000

ctgtcgacag gtcctctgtc tgtatgatct tgccaaggag ttgggctgtt cctacacaga   6060

tgttgctgct caggatggtg aagccatgct ccggaaaatc ttggcctctc agcagcctga   6120

ccgatgcaaa cgagcccagg ccttcatcag cacacagggc cttaagccag atactgtggc   6180

tgaactcgtg gcagaagagg tgacacggga gctgcttact tcatcacagg gaacaggaca   6240

taagcagatg ttcaacccaa cagaggaaag ccagacattt cttcagctga ccactctgtg   6300

tcaagaccgc acattggtag gcatgaagtt gttggataag atttcctccg ttccccatgg   6360

ggaactgtct tgcaccacag agctcctgat cctggcccat cattgcttca ccctgacgtg   6420

ccacatggag ggcatcatcc gagtcctaca ggccgcccac atgctcacag ataaccacct   6480

ggcccccagt gaggagtatg ggctggtggt acggctcctc actggcattg gaaggtacaa   6540

cgagatgaca tacatatttg atttgctgca taaaaagcac tactttgaag tgctaatgag   6600

gaagaagttg gatccgagtg gtaccctgaa aacagccctg ctggactaca tcaaacgctg   6660

ccgtcctgga gacagtgaaa agcacaatat gattgccctg tgcttcagca tgtgccggga   6720

gattggcgag aaccacgagg cagctgcccg catccaactg aaattgattg agtctcagcc   6780

ctgggaggac agcctcaagg atgggcacca gctgaaacaa ctgctgctga aggccctgac   6840

tctgatgttg gatgcagcag agagttatgc caaggactcc tgtgtgcgac aggcccagca   6900

ctgtcagcgg ctcaccaagt tgataactct gcagattcac tttctgaaca ctggccagaa   6960

cacaatgctc atcaacttgg gccgccacaa gctgatggac tgtattctgg ccctacctcg   7020

gttctaccag gcttctattg tggctgaggc ctacgatttt gttccagatt gggctgaaat   7080

tttataccag caagtgattc ttaaaggaga ctttaattac ttggaagaat ttaagcagca   7140

aaggttatta aagtccagta tatttgaaga gatttccaaa aaatataaac aacatcagcc   7200

tactgacatg gtcatggaaa acctgaagaa attactcaca tattgtgaag atgtttacct   7260

gtattacaag ttggcatacg aacacaagtt ttatgaaatt gtaaatgtgc ttctgaagga   7320

ccctcagaca ggttgctgtc taaaggacat gctagcaggt tagatgattt cataggtgtc   7380

tgttttcttg tactgttagc agattctgac agatgtgatg agaagaagaa tgcattggag   7440

atctttgcta aagttgaaca atcccggtac tgtaccatat cagtcctttg tgggtagtag   7500

gtagcaagta agaaactttt caggaggaaa ttcctattta aaatagattg attttagatg   7560

attgttcatc cacaccattt tatatagata ctagtattaa gatcaaaagc ttcctcttcc   7620

tcaggacagc ttctacttta gatgatccaa taatgattaa agaatacctg tacctgcaga   7680

ttccagtttc aaagaaattt aattattatt tacacagtta aggaacaggt gatacatttt   7740

catttgttag aaactgatct ttctgtaata aaatagattt tcaattcaaa aaaaaaaaaa   7800

aaaaaaaaaa aaaaaaa                                                  7817


<210>  1050
<211>  2466
<212>  DNA
<213>  Homo sapiens

<400>  1050
cctggccacc ggctcgcggc gcgtggaggc tgctcccagc cgcgcccgag tcagactcgg     60

gtgggggtcc cggcggcggt agcggcggcg gcggtgcgag catgtcgtgg ctcttcggcg    120

ttaacaaggg ccccaagggt gaaggcgcgg ggccgccgcc gcctttgccg cccgcgcagc    180

ccggggccga gggcggcggg gaccgcggtt tgggagaccg gccggcgccc aaggacaaat    240

ggagcaactt cgaccccacc ggcctggagc gcgccgccaa ggcggcgcgc gagctggagc    300

actcgcgtta cgccaaggag gccctgaatc tggcgcagat gcaggagcag acgctgcagt    360

tggagcaaca gtccaagctc aaagagtatg aggccgccgt ggagcagctc aagagcgagc    420

agatccgggc gcaggctgag gagaggagga agaccctgag cgaggagacc cggcagcacc    480

aggccagggc ccagtatcaa gacaagctgg cccggcagcg ctacgaggac caactgaagc    540

agcagcaact tctcaatgag gagaatttac ggaagcagga ggagtccgtg cagaagcagg    600

aagccatgcg gcgagccacc gtggagcggg agatggagct gcggcacaag aatgagatgc    660

tgcgagtgga gaccgaggcc cgggcgcgcg ccaaggccga gcgggagaat gcagacatca    720

tccgcgagca gatccgcctg aaggcgtccg agcaccgtca gaccgtcttg gagtccatca    780

ggacggctgg caccttgttt ggggaaggat tccgtgcctt tgtgacagac cgggacaaag    840

tgacagccac ggtggctggg ctgacgctgc tggctgtcgg ggtctactca gccaagaatg    900

cgacagccgt cactggccgc ttcatcgagg ctcggctggg gaagccgtcc ctagtgaggg    960

agacgtcccg catcacggtg ctggaggcgc tgcggcaccc catccaggtc agccggcggc   1020

tcctcagtcg accccaggac gtgctggagg gtgttgtgct tagtcccagc ctggaagcac   1080

gggtgcgcga catcgccata gcaaccagga acaccaagaa gaaccggggc ctgtacaggc   1140

acatcctgct gtatgggcca ccaggcaccg ggaagacgct gtttgccaag aaactcgccc   1200

tgcactcagg catggactac gccatcatga caggcgggga cgtggccccc atggggcggg   1260

aaggcgtgac cgccatgcac aagctctttg actgggccaa taccagccgg cgcggcctcc   1320

tgctcttcat ggatgaagca gacgccttcc ttcggaagcg agccactgag gagataagca   1380

aggacctcag agccacactg aacgccttcc tgtaccacat gggccaacac agcaacaaat   1440

tcatgctggt cctggccagc aatctgcctg agcagttcga ctgtgccatc aacagccgca   1500

ttgacgtgat ggtccacttc gacctgccgc agcaggagga gcgggagcgc ctggtgagac   1560

tgcattttga caactgtgtt cttaagccgg ccacagaagg aaaacggcgc ctgaagctgg   1620

cccagtttga ctacgggagg aagtgctcgg aggtcgctcg gctgacggag ggcatgtcgg   1680

gccgggagat cgctcagctg gccgtgtcct ggcaggccac ggcatatgcc tccaaggacg   1740

gggtcctcac tgaggccatg atggacgcct gtgtgcaaga tgctgtccag cagtaccgac   1800

agaagatgcg ctggctgaag gcggaggggc ctgggcgcgg ggtcgagcac cccctatccg   1860

gagtccaagg cgagaccctc acctcatgga gcctggccac ggacccctcc tacccctgcc   1920

ttgccggccc ctgcacattt aggatatgct cctggatggg gactgggctg tgcccagggc   1980

ctctgtcccc caggatgtct tgtggtggcg gtcggccgtt ctgcccccca gggcaccccc   2040

tgttgtaggc actggctagg gaggggcagg cctccttcct gcccctcgag acactcttgg   2100

gagatgcatt ttccgtctgg ctcacagggg gagggtgagg ctttgtaccc cagcccctgc   2160

ccaggccact gtgagggtgg gtgctggctg agcccctggg gcagaaggag tggggcaggc   2220

ggggtctttg ttctcggctc ccacagcaga gccaggtgag ggggggcctg ccaggactag   2280

acagaagtgg ggcggcctga accctgcttc cagccatggc caggggccac ggaacccggc   2340

aggggtgtct gaggccgccc tgtcagctgg ccggtccaag cctgtggctg gagctggtgt   2400

gtgtttatct aataaagtcc cacaggtgcc tcaaaaaaaa aaaaaaaaaa aaaaaaaaaa   2460

aaaaaa                                                              2466


<210>  1051
<211>  3540
<212>  DNA
<213>  Homo sapiens

<400>  1051
cagaggagga gctcgctgcc gggggacgct gggctgagcg gccggcggcg cgggcccggc     60

ggcggcggca gcggggtccg ggtccggagc gccacatgag acggtttaag cggaagcatc    120

ttactgccat tgactgccag catttggctc ggagtcactt ggctgtgacc cagcccttcg    180

gtcaaagatg gacaaacaga gatccgaacc atggtctcta tcctaaaccg agaacaaaaa    240

gagggagtag gggtcaggga agtcaaagat gcatccctga gttcttccta gcaggcaagc    300

agccgtgcac caatgacatg gccaaaagca attctgttgg ccaggacagc tgtcaggact    360

ctgagggtga catgatcttt cctgcagaga gcagctgtgc actgcctcag gaaggcagtg    420

cagggccggg ctcaccaggg tctgccccgc cctccaggaa gcggtcttgg tcctctgagg    480

aagagagtaa ccaggctacc gggaccagcc ggtgggatgg agtttctaag aaagctccac    540

ggcaccattt gtctgtgcca tgcacaaggc ctagggaggc caggcaagaa gcagaggaca    600

gtacgtctcg gctctctgcg gagtctggtg aaaccgacca agatgctggg gacgtgggtc    660

ctgatcccat tcctgactca tactatgggc ttcttgggac cttgccctgc caggaagcac    720

tgagccacat ttgcagcctg cctagtgagg tcctgaggca cgtgtttgcc ttcctcccgg    780

tggaagacct ctattggaac ctgagcttgg tgtgccactt gtggagggag atcatcagtg    840

acccgctgtt cattccttgg aagaagctgt accatcgata cctgatgaat gaagagcaag    900

ctgtcagcaa agtggacggc atcctgtcta actgtggcat agaaaaggag tcagacctgt    960

gtgtgctgaa cctcatacga tacacagcca ccactaagtg ctctccgagt gtggatcccg   1020

agagggtgct gtggagtctg agggaccacc ccctcctccc cgaggctgag gcgtgtgtgc   1080

ggcaacacct ccccgacctc tacgctgctg ccgggggtgt caacatctgg gccctggtgg   1140

cggctgtggt gctcctctcc agcagtgtga atgacatcca gcgactgctc ttctgcctcc   1200

ggagacccag ctccacggtg accatgccag atgtcaccga gaccctgtac tgcatagccg   1260

tgcttctcta cgccatgagg gagaagggga ttaacatcag caataggatt cactacaaca   1320

ttttctattg cctatatctt caggagaatt cctgcactca ggccacaaaa gttaaagagg   1380

agccatctgt ctggccaggc aagaaaacca tccaacttac acatgaacaa cagctgattc   1440

tgaatcacaa gatggaacct ctccaggtgg tgaaaattat ggcctttgcc ggcactggga   1500

agacctcaac gctggtcaag tatgcagaga agtggtctca gagcaggttt ctgtatgtga   1560

cattcaacaa gagcatcgca aagcaggccg aacgcgtctt ccccagcaac gtcatctgca   1620

aaaccttcca ctccatggcc tacgggcaca tagggcggaa gtaccagtca aagaagaagt   1680

tgaatctctt caagttaaca cccttcatgg tcaactccgt ccttgctgaa gggaagggtg   1740

gattcataag agccaagctt gtgtgtaaga ctctagaaaa cttctttgcc tcggctgacg   1800

aagagctgac cattgatcac gtgcctattt ggtgtaagaa cagccaagga cagagagtca   1860

tggttgagca gagtgaaaaa ctgaatggtg tccttgaagc gagccgcctc tgggataaca   1920

tgcggaagct gggggagtgc acagaagagg cgcaccagat gactcatgac ggctacttga   1980

aactctggca gctgagcaag ccttcgctgg cctcttttga cgccatcttt gtggatgagg   2040

cccaggactg cacaccagct atcatgaaca tagttctgtc tcagccatgt gggaaaatct   2100

ttgtagggga cccgcaccag cagatctata ccttccgggg tgcggtcaac gccctgttca   2160

cagtgcccca cacccacgtc ttctatctca cgcagagttt tcggtttggt gtggaaatag   2220

cttatgtggg agctactatc ttggatgttt gcaagagagt caggaaaaag actttggttg   2280

gaggaaacca tcagagtggc attagaggtg acgcaaaggg gcaagtggcc ttgttgtccc   2340

ggaccaacgc caacgtgttt gatgaggccg tacgggtgac ggaaggggaa ttcccttcaa   2400

ggatacattt gattgggggg attaaatcat ttggattgga cagaatcatt gatatttgga   2460

tccttcttca gccagaggaa gaacggagga aacaaaacct cgtcattaaa gacaaattta   2520

tcagaagatg ggtgcacaaa gaaggcttta gtggcttcaa gaggtatgtg accgctgccg   2580

aggacaagga gcttgaagcc aagatcgcag ttgttgaaaa gtataacatc aggattccag   2640

agctggtgca aaggatagaa aaatgccata tagaagattt ggactttgca gagtacattc   2700

tgggcactgt gcacaaagcc aaaggcctgg agtttgacac tgtgcatgtt ttggatgatt   2760

ttgtgaaagt gccttgtgcc cggcataacc tgccccagct tccgcacttc agagttgagt   2820

cattttctga ggatgaatgg aatttactgt atgttgcagt aactcgagcc aagaagcgtc   2880

tcatcatgac caaatcattg gaaaacattt tgactttggc tggggagtac ttcttgcaag   2940

cagagctgac aagcaacgtc ttaaaaacag gcgtggtgcg ctgctgcgtg ggacagtgca   3000

acaatgccat ccctgttgac accgtcctta ccatgaagaa gctgcccatc acctatagca   3060

acaggaagga aaacaagggg ggctacctct gccactcctg tgcggagcag cgcatcgggc   3120

ccctggcgtt cctgacagcc tccccggagc aggtgcgcgc catggagcgc actgtggaga   3180

acatcgtact gccccggcat gaggccctgc tcttcctcgt cttctgagga caaggcgcac   3240

gttctccgca gtgcagagca gcttgccgag gaccccgcgt gaagaaagcc agcgaggggg   3300

gcttctgctc cctgagactc tgggttcacc cacagcactt tctgaggaag aggacaccag   3360

cccaagctgg acctgccatt tctccactcc ctacagacag ccagtctcca cttgcctccc   3420

ctctggatgt atctggtcag ggaagtgggg gatgttcttt tgataaaaaa aaaaaaaaaa   3480

atttatgtat ttaaactttt attacaagat ttcaattaaa caggcaccat agcactggca   3540


<210>  1052
<211>  3507
<212>  DNA
<213>  Homo sapiens

<400>  1052
tttcgccctt gtcgcagctg aaccgccgac tacgagctcc tgcaccgcgc acacaccccg     60

cgcgcttcgc tctcggcctc gcccggccac cgtcgctctc tagaacgccg cgcccgtgac    120

ccggaagagc attctcctta gcaactgcgg gactgcggcg gcgccggcct ccggggagaa    180

acgcgaatga caacagagct gctcaaggcg ggaactctga gctaagcagt ggaggtttct    240

ctggatctgg agagaagagt gaccttggag ccaataatga gccatcctga ctacagaatg    300

aacctccggc ccctggggac ccccagaggt gtgtctgctg tggctggtcc acatgacatt    360

ggtgcttcgc caggtgacaa aaagtcaaag aacaggtcca cacgagggaa gaaaaagagc    420

atatttgaaa cttacatgtc caaggaggat gtttcagaag gcttgaagag aggaacactc    480

atccagggtg tattgagaat taatccaaag aagtttcatg aagccttcat tccttccccg    540

gatggtgatc gagacatttt tattgatggg gttgttgctc gtaatagagc cttaaatggg    600

gatctggtgg tcgtgaaact gcttcccgag gagcattgga aggtagttaa accagagagc    660

aatgacaaag aaacagaagc tgcgtatgaa tcagatatcc ccgaggagct ctgtggacac    720

catctcccgc aacagtccct gaaaagctat aatgacagtc ctgatgtcat tgtagaggct    780

cagtttgatg gcagcgactc agaagatgga catggcatca cacaaaatgt gctggttgat    840

ggtgttaaga aactctcagt ttgtgtttct gagaaaggaa gagaggatgg tgatgcaccg    900

gttacaaaag atgagaccac ctgcatttca caagacacaa gagctttatc ggagaaatcc    960

ctgcaaagat cagcaaaggt ggtttacatc ttggagaaaa aacattctcg agcagcaacc   1020

ggcttcctca aactcttggc tgataagaac agcgaactgt ttaggaaata cgccctgttt   1080

tctccctcag accaccgagt gcctagaatt tatgtgcctc tcaaggactg tccccaggac   1140

tttgtggcac ggcctaaaga ttatgccaac acactgttca tctgccgcat tgtggactgg   1200

aaggaggact gcaattttgc cctggggcag ctggctaaga gtcttgggca ggctggtgaa   1260

attgagcctg aaacagaagg aatactaaca gagtatggcg tggatttctc tgatttctct   1320

tcagaagttc tagaatgtct tcctcaaggc ctgccatgga caattccacc agaggagttc   1380

agcaagagaa gggatttaag aaaagactgt atcttcacca ttgacccatc aaccgcccga   1440

gacctcgatg atgccctctc ctgcaagcca ctcgctgacg gcaacttcaa agtgggagtt   1500

cacattgctg acgtgagtta ctttgttccg gagggatctg atctggataa agtggctgcc   1560

gagagggcta caagcgtcta cttggttcaa aaggtggtcc ccatgcttcc caggctgctg   1620

tgtgaggagc tgtgcagcct caaccccatg tccgacaagc tgaccttctc tgtgatctgg   1680

acactgactc cagagggcaa gatccttgat gaatggtttg gccggaccat catccgctcc   1740

tgcaccaaac ttagctacga gcatgcacag agcatgattg aaagcccaac tgagaaaatc   1800

cctgcgaaag agctgccccc catttcccca gagcatagca gcgaggaggt acaccaggcc   1860

gtcttgaatc tccacggaat tgccaagcag ttacgccagc agcgctttgt ggacggcgca   1920

cttcgtttgg atcagctaaa gcttgctttc actctggacc acgagaccgg attgcctcaa   1980

ggatgtcata tctatgagta ccgcgagagc aacaagctcg tggaggagtt catgctcttg   2040

gccaacatgg cagtggccca caagatccac cgcgccttcc ccgagcaggc cctgctgcgc   2100

cggcaccccc cgccccaaac aaggatgctc agtgacctgg tggaattctg cgaccagatg   2160

gggctgcccg tggacttcag ctccgcagga gccctcaata aaagcctgac ccaaacattt   2220

ggagatgaca agtactcact ggcccgcaag gaggtgctca ccaacatgtg ctcccggccc   2280

atgcagatgg cactgtactt ctgctcgggg ctgctgcagg acccagcgca gttccggcac   2340

tacgcgctca atgtgcccct gtacacacac ttcacctcgc ccatccgccg ctttgccgac   2400

gtcctggtgc accgcctcct ggctgccgcg ttaggctata gggagcgact agacatggcg   2460

cccgataccc tgcagaaaca ggcggaccac tgtaacgacc gccgcatggc gtccaagcgc   2520

gtgcaggagc tcagtaccag tctcttcttt gctgttctgg tcaaggagag tggccccctg   2580

gagtcagaag ccatggtgat gggcatcctg aagcaagcct tcgacgtgct ggtgctgcgc   2640

tacggcgtgc agaagcgcat ctactgcaac gcactggccc tgcggtccca ccacttccag   2700

aaggtgggca agaagccgga actcacgctg gtctgggagc ctgaggacat ggagcaggag   2760

ccagcacagc aggtcatcac catcttcagc ctggtggagg tggtcctgca ggcagagtcc   2820

acagccctca agtacagcgc catcctgaag cggccaggca cccagggcca cctgggccct   2880

gagaaggagg aggaggagtc tgacggtgag cccgaggact caagcaccag ctgagctcca   2940

ccagccgcct gccccgcctg ccccgcctgc ctgtcccgcc acactggctt taggacctgt   3000

tgacacggag gggggttttt aatttggttt ttaacaactc aggggtttgt ttttattttt   3060

atttaatttt tgcagctcaa cttttaaaca aactgcaggg gagagggtgg ggctggaagg   3120

aaggctgagg cctggtcagc agtgacccca gcagagcagg ccccagtcct cctgggaggc   3180

tggcccccct tttttctggg ccctactgcc ctcctctgcc caggaaatgg gggggtttca   3240

gcaactcagt gtcacagaat aaaatcaagt gtggagtgcc atctggtgtg tagggcgcct   3300

ctgggaagcc tgggcagcag aatgcccctt gcacccaggg caagggaccc agttcaggct   3360

tcacccctcg ctgctgagcc gatgtcaaca cctggaactt tcctgtcagt tccaacacga   3420

ttcagagctg gctgcctggc agatgattga tactggagtc tcattctgcc tgattaaaaa   3480

tggaattagt atgcaacact gaaaaaa                                       3507


<210>  1053
<211>  2055
<212>  DNA
<213>  Homo sapiens

<400>  1053
gggggcgggt ccgcggctgg ccggccgggc gggcgccgac aatgagcctc cataaaaggg     60

agcggcgggg ggcaggggcc ccggattgag ccctccccgc ccgggctccc gacgcgccga    120

ggtctcgggg aggcccggac gcgccggtcg caggcccggc cggcgagcgg cgggcgggcg    180

gcggggaggg ggctgcgcgg ggcgggcggc gggcccggcg ctattccggc caggaggcgg    240

gaggcggttg ccggctgcgc gccgaagcct gcgcgccagt cctccggcca ctgctatcgc    300

ccacggccgc accatggccc taaaggccga gggcgccgca ctcgactgct tcgaggtgac    360

gctgaaatgc gaggaagggg aggacgagga ggaggccatg gtggtggccg taattccgcg    420

gcccgagccg atgctcagag tgacccaaca ggagaagacc ccaccgccta gacccagccc    480

gctagaggca ggcagtgatg gctgtgagga gccgaagcag caggtgtctt gggagcagga    540

gttcctggtg ggcagcagcc caggaggcag cgggcgggca ctgtgcatgg tgtgtggcgc    600

tgagatccgg gcaccctcgg ccgacacagc tcgctcgcac atcttggagc agcaccctca    660

caccttggac ctgagccctt ctgagaagag caatatcctg gaggcctgga gtgaaggggt    720

ggccctcttg caagacgtga gagctgagca gccgtcccca cccaactcag actcgggcca    780

ggatgcccac ccagacccag acgccaaccc agacgctgcc agaatgccag ccgaaatcgt    840

cgttctcctt gactctgagg ataacccatc cctccctaaa aggagccggc ccaggggact    900

ccgccccctc gagcttcctg ctgtccctgc cacagagcca ggaaataaga agccccgtgg    960

tcagagatgg aaggaacccc caggggaaga gccagtcaga aagaaaagag gcagacctat   1020

gaccaaaaac ctggaccctg acccagagcc cccatcgcca gactcgccca cggagacttt   1080

cgcagcacca gccgaggtcc gacacttcac tgacggcagc ttccccgccg gcttcgtctt   1140

gcagctcttc tcccacaccc agctcagggg cccagacagc aaggactcac ccaaagacag   1200

ggaagtggca gaaggaggcc ttccccgggc ggagagcccc tctccagctc cccctccggg   1260

gctccgcggg acactggatc tccaggttat ccgcgtgcgg atggaggagc ccccagcggt   1320

cagcctcctg caagactggt ccaggcaccc ccagggcacc aagcgtgtgg gagcaggtga   1380

cacctcagac tggcccacag ttctgtcaga atccagcacc actgtggcag ggaagccgga   1440

aaaagggaat ggagtgtaaa ttcttgcttt cctggggagg gagggaggga tgaggcagcg   1500

tcccccagtg gcttataact cagagctgcc tggctcaccc acctggtgga gagagtagaa   1560

acaggtgcca gggcaggagg gggctggggc agcatccact gttatttcgg ggcactggaa   1620

agtgtctgtt cctggccagg cctgaggtcg gcgagggtgg ctgaggctgt tgtgcagtag   1680

ggcactgggc ctgtggagaa cacctacccc agtccttcgc tgacccccac ctctgtttgt   1740

cccccatgac ctcctcccac cctccccctg ctccccacca ttctcccttg gcacagtgcc   1800

ttacacaaga gtggtcataa gggggtttga actgagtccc actacctcgg gggacacctc   1860

tcctccccac ttgttcaggc ttctaaacca ggaggcctcc attacctctt cctgtcccac   1920

ccctgcagag gcctgaagct gggcctgggc accccattca ctcccgttct catttacatc   1980

tgttttcctg ttgtatatat cacctttgtt gacaataaat tatttttttt tattaagaaa   2040

aaaaaaaaaa aaaaa                                                    2055


<210>  1054
<211>  3265
<212>  DNA
<213>  Homo sapiens

<400>  1054
ggctccgcgt ccggcgcctg tttgtgctgc ggcgctgtgg caccggacgg ccctgccacc     60

ccacccccgg gagccgagag cggccccggg agagtccgag ggcccggggg ggtctggaga    120

ctgcggcccc gggcccacag cgccccctcc aggccccttc cccgcgcccg acagcgcccc    180

ctcggggtgg tggtacggcg cccttcgcgc gcgccccggg gtgcttcccc ttcccctctc    240

cccggccgtg gcccccgcgg cttagacgcc tcctccgccg ccgccgctcg gagcaacccg    300

ggggccggat ggacggggcc gcggggcccg gtgacggccc tgctcgggag gccctccagt    360

ctctgagcca gcggcttcgg gtgcaggagc aggagatgga actggtaaag gcagccctgg    420

cagaagccct tcgcctgctg cggctgcagg tgcccccttc ctccctgcag ggctctggca    480

caccagctcc tccgggggac agtcttgcag cccccccagg actgccaccc acgtgcaccc    540

cttccttggt gagccgaggc acccagacgg agacagaggt ggagctcaag tcatcccctg    600

gaccccctgg cctgagcaat ggacccccag cccctcaggg ggccagcgaa gagcctagcg    660

ggacccaatc tgaaggaggg ggcagcagca gcagtggtgc tggctcccct ggccccccgg    720

ggatcctcag gcccttgcag cccccacagc gtgctgacac gccgcgaaga aattcttcct    780

cctcctcatc cccctcagag cggcctcggc agaagctctc caggaaggca atctcctccg    840

ccaacctgtt agtgcggtcc gggagcacag agagccgtgg gggaaaagac cccctctcca    900

gccctggggg ccctggatct cggaggagca attacaattt ggaaggcatc tcagtgaaga    960

tgttccttcg agggcgcccc attaccatgt acatcccgtc tggcatccgc agccttgagg   1020

agctgccgag tggcccaccg ccagagaccc tcagccttga ctgggtttat gggtacaggg   1080

gtcgtgactc ccgctctaat ctgtttgtgt tgcgctctgg ggaggtggtc tactttatcg   1140

cctgtgtggt ggtgctgtac cggcctggag gaggcccagg gggtcctgga ggtggcggcc   1200

agagacatta ccgggggcac acagactgcg ttcgatgcct tgctgttcac cctgatggtg   1260

ttcgggtagc ctcgggacag acagctggag tggataagga tggaaagccc ctgcagcctg   1320

tggttcacat ctgggactca gagacgctgt tgaaactgca ggagattgga ctgggggcct   1380

tcgagcgggg tgttggggcc ctggcctttt cagctgcgga tcagggtgcc tttctttgtg   1440

tggtggatga ttccaatgag cacatgctgt cggtgtggga ctgcagccgg ggaatgaagc   1500

tggctgagat caagagtaca aatgactcag tcctggccgt tggcttcaac cctcgtgaca   1560

gcagctgcat cgtcaccagt gggaaatctc acgtccactt ctggaattgg agtggtggag   1620

taggggttcc tgggaatggg acccttaccc ggaaacaggg tgtctttggg aaatacaaga   1680

aacccaagtt tatcccttgc tttgtgttcc ttccggatgg agacattctc actggagact   1740

cagaggggaa cattctcacc tgggggcgga gcccttcaga ttccaagacc ccaggcaggg   1800

gtggcgccaa agagacctat gggattgtgg cccaggctca cgctcatgaa ggttctatct   1860

tcgccttgtg tctccggagg gacgggacag tgctgagtgg tggcgggcgg gaccgccggc   1920

tggtacagtg ggggcccggg ttggtggccc tccaggaggc tgagattccc gagcacttcg   1980

gggccgtgcg agccattgct gaagggcttg gctctgagct gctggtggga accacgaaga   2040

atgcattgct gaggggagac ctggcccagg gcttctcccc tgtaatccag ggccacactg   2100

atgagctctg ggggctctgc acacacccct cccagaaccg cttcctcacc tgcggccacg   2160

accggcagct ctgcctgtgg gatggggaga gccatgcact ggcctggagc atcgacctca   2220

aggagactgg tctctgtgct gacttccacc cgagtggggc agttgtggcc gtaggactga   2280

acacggggag gtggttggtt ttggacacag agaccagaga gatcgtgtct gatgtcattg   2340

atggcaatga gcagctctca gtggtccggt acagcccaga tgggttgtac ctggccattg   2400

gttcccatga caacgtgatc tacatctata gtgtttccag tgatggtgcc aaatccagcc   2460

gctttggccg ctgtatgggt cactccagct tcatcactca tcttgactgg tccaaggatg   2520

ggaatttcat catgtccaat tctggggact atgagattct ttactgggac gtggctggag   2580

gctgcaagca gctgaagaat cgctatgaga gccgagaccg ggaatgggct acctacacct   2640

gtgtgctggg ctttcacgtc tacggcgtct ggccggacgg ctccgatggg accgacatca   2700

actccctgtg ccgctcccac aacgagcgcg tggtggcggt ggccgacgac ttctgcaaag   2760

tgcatctctt ccagtacccg tgcgctcgtg ccaaggcgcc gagccgcatg tacgggggcc   2820

acggcagcca cgtgaccagc gtccgattca cgcacgacga ctcgcacctc gtctcgctgg   2880

gcggcaagga cgccagcatc ttccagtggc gagtgctggg cgctgggggc gcggggccgg   2940

cgcccgccac gccctctcga accccctccc tgtcccccgc ctcctccctc gacgtttgat   3000

cgctgcctgg cgggaccgac tggcccggcg gcgtggcccc gccccgccct gcccttccct   3060

ggcccaatcc cccacgacta ggggccgact ctttcctgga ctgacttcga gacattcccg   3120

atcgcgcatt ttcctggagg gcgcgaacgg cgcccctgca cacactgttt agacccgctg   3180

gctgagccgg gcagccccag cctaggcctt gactcccgct gcctgctgag gggcaataaa   3240

ccagaaccaa agtcgaaaaa aaaaa                                         3265


<210>  1055
<211>  2019
<212>  DNA
<213>  Homo sapiens

<400>  1055
gggggctcgg gctgggggcg cggcctgtgc cggccgcccc accctccttg cataaaagcc     60

ggagcccgcg gggccggcgc tctcagcccg tcggttcccg agcgccttcc cggtgacccc    120

gcagtgggtg tgtgagggga ggacggacag acccagacgc cgccggacca ggaggacgct    180

gacgaggcac catgcgtgag atcgtgcaca tccaggcggg ccagtgcggc aaccagatcg    240

gcgccaagtt ttgggaggtc atcagtgatg agcatgggat tgaccccact ggcagttacc    300

atggagacag tgatttgcag ctggagagaa tcaatgttta ctacaatgaa gccactggta    360

acaaatatgt tcctcgggcc atcctcgtgg atctggagcc aggcacgatg gattcggtta    420

ggtctggacc attcggccag atcttcagac cagacaattt cgtgtttggc cagagtggag    480

ccgggaataa ctgggccaag ggccactaca cagagggagc cgagctggtc gactcggtcc    540

tggatgtggt gaggaaggag tcagagagct gtgactgtct ccagggcttc cagctgaccc    600

actctctggg gggcggcacg gggtccggga tgggcaccct gctcatcagc aagatccggg    660

aagagtaccc agaccgcatc atgaacacct tcagcgtcat gccctcaccc aaggtgtcag    720

acacggtggt ggagccctac aacgccaccc tctcggtcca ccagctggtg gaaaacacag    780

atgaaaccta ctgcattgac aacgaggccc tgtatgacat ctgcttccgc accctgaagc    840

tgaccacccc cacctacggg gacctcaacc acctggtgtc ggccaccatg agcggggtca    900

ccacctgcct gcgcttcccg ggccagctga acgcagacct gcgcaagctg gcggtgaaca    960

tggtgccctt ccctcgcctg cacttcttca tgcccggctt cgcgcccctg accagccggg   1020

gcagccagca gtaccgggcg ctcacggtgc ccgagctcac ccagcagatg ttcgactcca   1080

agaacatgat ggccgcctgc gacccgcgcc acggccgcta cctgacggtg gctgccatct   1140

tccggggccg catgtccatg aaggaggtgg acgagcagat gctcaacgtg cagaacaaga   1200

acagcagcta cttcgtggag tggatcccca acaacgtgaa gacggccgtg tgcgacatcc   1260

cgccccgcgg cctgaagatg tcggccacct tcatcggcaa cagcacggcc atccaggagc   1320

tgttcaagcg catctccgag cagttcacgg ccatgttccg gcgcaaggcc ttcctgcact   1380

ggtacacggg cgagggcatg gacgagatgg agttcaccga ggccgagagc aacatgaacg   1440

acctggtgtc cgagtaccag cagtaccagg acgccacggc cgacgaacaa ggggagttcg   1500

aggaggagga gggcgaggac gaggcgtaga tgcccccgcg agacgggtta gggaaagcgg   1560

aggaggaaag cgagggggtg gggggcttcc cgggacgata acctggcagt ggaaggaaag   1620

aagcatggtc tactttaggt gtgcgctggg tctctggtgc tcttcactgt tgcctgtcac   1680

tttttttttc cttttttgta atattgatga catcaatgta acatttgaga tatttctgaa   1740

ttactgttgt aatggctaaa atcacataaa cgtttgtgtc ggaatggtgt cctctctttc   1800

tcttcctttt tctctttatt aacgatttaa atgtaacttt ctgaacacat tgcattgaat   1860

tcttccttta acaaaaagca aaggcgtagg taaaagctca aatgaattta ttctttcggt   1920

atggtaaaat tgaaccaatc acagttaaga tgagagatca acctgagttt taaaatacct   1980

ttaataaata ttagttgaaa aaatgtctac ttgaaagca                          2019


<210>  1056
<211>  2445
<212>  DNA
<213>  Homo sapiens

<400>  1056
ataaaagccc aggggcaagc ggtccggata acggctagcc tgaggagctg ctgcgacagt     60

ccactacctt tttcgagagt gactcccgtt gtcccaaggc ttcccagagc gaacctgtgc    120

ggctgcaggc accggcgcgt cgagtttccg gcgtccggaa ggaccgagct cttctcgcgg    180

atccagtgtt ccgtttccag cccccaatct cagagcggag ccgacagaga gcagggaacc    240

ggcatggcca aagccgcggc gatcggcatc gacctgggca ccacctactc ctgcgtgggg    300

gtgttccaac acggcaaggt ggagatcatc gccaacgacc agggcaaccg caccaccccc    360

agctacgtgg ccttcacgga caccgagcgg ctcatcgggg atgcggccaa gaaccaggtg    420

gcgctgaacc cgcagaacac cgtgtttgac gcgaagcggc tgattggccg caagttcggc    480

gacccggtgg tgcagtcgga catgaagcac tggcctttcc aggtgatcaa cgacggagac    540

aagcccaagg tgcaggtgag ctacaagggg gagaccaagg cattctaccc cgaggagatc    600

tcgtccatgg tgctgaccaa gatgaaggag atcgccgagg cgtacctggg ctacccggtg    660

accaacgcgg tgatcaccgt gccggcctac ttcaacgact cgcagcgcca ggccaccaag    720

gatgcgggtg tgatcgcggg gctcaacgtg ctgcggatca tcaacgagcc cacggccgcc    780

gccatcgcct acggcctgga cagaacgggc aagggggagc gcaacgtgct catctttgac    840

ctgggcgggg gcaccttcga cgtgtccatc ctgacgatcg acgacggcat cttcgaggtg    900

aaggccacgg ccggggacac ccacctgggt ggggaggact ttgacaacag gctggtgaac    960

cacttcgtgg aggagttcaa gagaaaacac aagaaggaca tcagccagaa caagcgagcc   1020

gtgaggcggc tgcgcaccgc ctgcgagagg gccaagagga ccctgtcgtc cagcacccag   1080

gccagcctgg agatcgactc cctgtttgag ggcatcgact tctacacgtc catcaccagg   1140

gcgaggttcg aggagctgtg ctccgacctg ttccgaagca ccctggagcc cgtggagaag   1200

gctctgcgcg acgccaagct ggacaaggcc cagattcacg acctggtcct ggtcgggggc   1260

tccacccgca tccccaaggt gcagaagctg ctgcaggact tcttcaacgg gcgcgacctg   1320

aacaagagca tcaaccccga cgaggctgtg gcctacgggg cggcggtgca ggcggccatc   1380

ctgatggggg acaagtccga gaacgtgcag gacctgctgc tgctggacgt ggctcccctg   1440

tcgctggggc tggagacggc cggaggcgtg atgactgccc tgatcaagcg caactccacc   1500

atccccacca agcagacgca gatcttcacc acctactccg acaaccaacc cggggtgctg   1560

atccaggtgt acgagggcga gagggccatg acgaaagaca acaatctgtt ggggcgcttc   1620

gagctgagcg gcatccctcc ggcccccagg ggcgtgcccc agatcgaggt gaccttcgac   1680

atcgatgcca acggcatcct gaacgtcacg gccacggaca agagcaccgg caaggccaac   1740

aagatcacca tcaccaacga caagggccgc ctgagcaagg aggagatcga gcgcatggtg   1800

caggaggcgg agaagtacaa agcggaggac gaggtgcagc gcgagagggt gtcagccaag   1860

aacgccctgg agtcctacgc cttcaacatg aagagcgccg tggaggatga ggggctcaag   1920

ggcaagatca gcgaggcgga caagaagaag gtgctggaca agtgtcaaga ggtcatctcg   1980

tggctggacg ccaacacctt ggccgagaag gacgagtttg agcacaagag gaaggagctg   2040

gagcaggtgt gtaaccccat catcagcgga ctgtaccagg gtgccggtgg tcccgggcct   2100

gggggcttcg gggctcaggg tcccaaggga gggtctgggt caggccccac cattgaggag   2160

gtagattagg ggcctttcca agattgctgt ttttgttttg gagcttcaag actttgcatt   2220

tcctagtatt tctgtttgtc agttctcaat ttcctgtgtt tgcaatgttg aaattttttg   2280

gtgaagtact gaacttgctt tttttccggt ttctacatgc agagatgaat ttatactgcc   2340

atcttacgac tatttcttct ttttaataca cttaactcag gccatttttt aagttggtta   2400

cttcaaagta aataaacttt aaaattcaaa aaaaaaaaaa aaaaa                   2445


<210>  1057
<211>  4674
<212>  DNA
<213>  Homo sapiens

<400>  1057
ctccttcccg ctccgcgtcc cgcccagcgg cgcagggggc cgggctccgg ctaggagggt     60

gggggccgcg ccggtgacag ccgatccccg cccctgctgc ccgccacgtc cctcacgtac    120

cactcggcag aggcgcgggg aaacctggcg tactggctgt ggcttctcta gcgggactcg    180

gcatgaggct ggcgcggctg cttcgcggag ccgccttggc cggcccgggc ccggggctgc    240

gcgccgccgg cttcagccgc agcttcagct cggactcggg ctccagcccg gcgtccgagc    300

gcggcgttcc gggccaggtg gacttctacg cgcgcttctc gccgtccccg ctctccatga    360

agcagttcct ggacttcgga tcagtgaatg cttgtgaaaa gacctcattt atgtttctgc    420

ggcaagagtt gcctgtcaga ctggcaaata taatgaaaga aataagtctc cttccagata    480

atcttctcag gacaccatcc gttcaattgg tacaaagctg gtatatccag agtcttcagg    540

agcttcttga ttttaaggac aaaagtgctg aggatgctaa agctatttat gactttacag    600

atactgtgat acggatcaga aaccgacaca atgatgtcat tcccacaatg gcccagggtg    660

tgattgaata caaggagagc tttggggtgg atcctgtcac cagccagaat gttcagtact    720

ttttggatcg attctacatg agtcgcattt caattagaat gttactcaat cagcactctt    780

tattgtttgg tggaaaaggc aaaggaagtc catctcatcg aaaacacatt ggaagcataa    840

atccaaactg caatgtactt gaagttatta aagatggcta tgaaaatgct aggcgtctgt    900

gtgatttgta ttatattaac tctcccgaac tagaacttga agaactaaat gcaaaatcac    960

caggacagcc aatacaagtg gtttatgtac catcccatct ctatcacatg gtgtttgaac   1020

ttttcaagaa tgcaatgaga gccactatgg aacaccatgc caacagaggt gtttaccccc   1080

ctattcaagt tcatgtcacg ctgggtaatg aggatttgac tgtgaagatg agtgaccgag   1140

gaggtggcgt tcctttgagg aaaattgaca gacttttcaa ctacatgtat tcaactgcac   1200

caagacctcg tgttgagacc tcccgcgcag tgcctctggc tggttttggt tatggattgc   1260

ccatatcacg tctttacgca caatacttcc aaggagacct gaagctgtat tccctagagg   1320

gttacgggac agatgcagtt atctacatta aggctctgtc aacagactca atagaaagac   1380

tcccagtgta taacaaagct gcctggaagc attacaacac caaccacgag gctgatgact   1440

ggtgcgtccc cagcagagaa cccaaagaca tgacgacgtt ccgcagtgcc tagacacact   1500

tgggacatcg gaaaatccaa atgtggcttt tgtattaaat ttggaaggta tggtgttcag   1560

aactatatta taccaagtac tttatttatc gttttcacaa aactatttga gtagaataaa   1620

tggaaactga attccatttg tgcccgttaa acctcctaaa ggatgaaatt gcacctattt   1680

tacacttata ttttcacagt taattgaaca tatttttaaa caactgtagt tttgggcaac   1740

ttttcacttt gtggtagact tcagaagtgt ggaaatcttc gggtttctat aggaaactag   1800

tttttttttt ttaagaaata ctttcattta tgtttgctag aaacattttc taaatgatag   1860

tgattagctg gttagccatc ttcctgttat ttggaggagt tctgccatct tttattcggt   1920

agtgacagct gtaatatggt cttcatgttt atcagtgact tgactacaag taaagcagaa   1980

aacagttggc ctgtaatcac agaaccagcc acccttcggc gtctacatgc attgtcttag   2040

ctctgaggtt aatttaccat ttttaaattt tattgtaaag aagtgtaatg actagctctc   2100

tgtggatcta tgccaaaatc atgggccatc ttttctaagt gtacttctga ttaatgcaag   2160

gggaaatttt tatactgaaa acaaacaaac aaactagcag ctactaaaat agagaagaaa   2220

ttgagggcaa agtaatatgt ctccaaaact gaactgattg cttgttgaga ttacctagaa   2280

agcttttgga aaaaaataga gcttttctgc atcctactcc agatacactg aatcggaatc   2340

cctagggcta gagcctagaa atctcacttt ttaaaatgct tccaaggtaa gtctgatgcc   2400

taccctaggt tgggaaccac tctttcaaag taaacagtga tgacacagca tttgctaaag   2460

taacatctgt aggttttggt ttccacctat ttaaagtcag atttatagac tcgaggagac   2520

agaaactgaa tcccacacct ggtgcaatta gaagcataat tagaagcaga agaacaaaat   2580

gccacgtaac caaagcatca gagccatcat tgcacgtgtc tttttttctt ttttcttttt   2640

tttttttcaa gacagggtct cgctcttttg cccaggatgg agtacagtgg catggtcaag   2700

gctcactgca gcttcaatct tctgggctca agtaatcctt ccacctcagc ctcccatata   2760

gctggaacta cagttgtgca ctaccacacc cagctaattt tttgatttct tgtggagatg   2820

aggtctcagt atgttcccag gctagtgttg aactcctgag ctcaagaaat cctcctgcct   2880

gagtctctga aagtgctggg attacaggcg tgagccacca cacatggcct attgcacaag   2940

tcttgacaaa caacatatat tttctaaaac tatccagatt tcattatcag ggaaaagttt   3000

gcttaggttt attacagcag tccttggcat ttgtatggta atttgtactt tacaaatact   3060

ttgatatatt ataactctat tggtctttga aacaaagcga tacagtgtag gtggtatcat   3120

tctctttctc actcagtgtg gcccagagtt gctcagaatt ggagcagagc ctgagacgta   3180

tctgcagatc ctgtcatcag ctggcaagtc caggagactg tgtcatttag agactgtgtt   3240

gttagttatc cctcaacatc ttctaaggtg gcaggaaata atattggaaa taacatttta   3300

aagtaaaaat tttaaagttt aaagaagagt tttgccactt aaacagggga gctttgtctg   3360

gaaaatacac tgagttgaaa cacttcatcc ttggaaggat tatataagat gaacagttgt   3420

gataaatgtg tagattagag ggatgtgaat gggcagttag tccagtgccc tcatttaaga   3480

ggccaagatc ctgattcaga ggaggcatcc tttgcccaga gctgcttagc taatctgacc   3540

aaatgttggg aaaaatgtct cacctaaccc actattcctt aattatggat tttgtgaaaa   3600

acaatagaac atgttaatga gtaatttata ttagttcgat gtattacaat tttttagctt   3660

taaattacag ttttcttata atgttgaaat gttttagaat cctttgaatc taagtatttg   3720

tttcctaaat gaaacatttg tacaacattt gatgttttta cttatgaaat attctcctcc   3780

cccaagaaaa tttaaacttt ttctctctat ttaaaagcta agaaatgttt taaaggaaaa   3840

atgaaattat cttcctttag cttattttta aggtaaaaca gctttttact ctgttattgt   3900

ggtaatggac agaatattac atacaaaaat attctgggag agctttttcc tagttggttt   3960

taaatcattg tgccacctga aaggttttta gattttatag gagctaattt gtccaccagc   4020

attaatgtaa cacagtgtag ttatgaaaat atattgaagg acaggaagtg gacacgaagt   4080

gatttttgta acctgagcag ttaatgaatg tgccaacatt ttctaggaag ggacagcaag   4140

aatattctgc tctgtagtta aaatactggc tggcttttga tgtcttcatg cttaattgtg   4200

atcactttct tgcactgtga tgtttttacg tgaatatgtt gaagtagaag tctaccatat   4260

tattttataa aatgttttct gtatggcaat aaactgaaaa catggatcaa cccttctttt   4320

gaaaataaac tgagtcaatt tagcctttta aaaatatagt catctctttt aaatagaatc   4380

ctcttccacc atcaaggctc aacattttgt aagcatccaa aaaattggta attagggggc   4440

ttgcactaaa tttcactatc ttcagtagag aggaactgtt tggaacttag atttccaatg   4500

tgtatattct aatggagaaa gcaagaggta gagtttgtat gtttgactta ccttagattt   4560

ttattttcca tacatactgc aaatgattga cttgttgcat aaatgaagat cttctgttgt   4620

gtgcttttca aacactgtaa ataaatttga aatttgaaaa aaaaaaaaaa aaaa         4674


<210>  1058
<211>  4276
<212>  DNA
<213>  Homo sapiens

<400>  1058
tgcgttttaa aaattgtctt tatttacatt ttacagaaag ttgagaaagt gttatttata     60

tggggggtag gggtgctgga gattatgaga ctaataacaa ccctcttagc tcgcaccctt    120

tggcaccact acagcttcca aactctggga ctttctcgac tagcttccct ttgtttagct    180

gtgaaatgga agaagcggtc cgggtgtggc ggctcatgcc tgtaacctga gcactctggg    240

aggcggagga tcgcttgagt ccagaagttc aagaccagct tgggcaacat agggtgaccc    300

tccaccctcc ccccgcccca ccacatcgct acaaaaaatt tttaaaaatt agccgggtgt    360

ggtggcgcaa gcctgtagtc tcagcgggag ctgagggagg agaatcgctt cagcccggga    420

ggtcgaggct gtagtgagcc gagatcgcgc tactgcactc ctgggcgaca gagcgagacc    480

ctgtctccaa aaaaaaaaaa aaaagaaaaa agaggaagtt gtatccaatt cagaaacgcg    540

gtccttcggg acctgctagt tttatacccc ggaggatcct ccccggcggg ctggcacggg    600

aggtggagaa agaggcttgg gcggccccgc tgtagccgcg tgtgggagga cgcacgggcc    660

tgcttcaaag ctttgggata acagcgcctc cgggggataa tgaatgcgga gcctccgttt    720

tcagtcgact tcagatgtgt ctccactttt ttccgctgta gccgcaaggc aaggaaacat    780

ttctcttccc gtactgagga ggctgaggag tgcactgggt gttcttttct cctctaaccc    840

agaactgcga gacagaggct gagtccctgt aaagaacagc tccagaaaag ccaggagagc    900

gcaggagggc atccgggagg ccaggagggg ttcgctgggg cctcaaccgc acccacatcg    960

gtcccacctg cgagggggcg ggacctcgtg gcgctggacc aatcagcacc cacctgcgct   1020

cacctggcct cctcccgctg gctcccgggg gctgcggtgc tcaaaggggc aagagctgag   1080

cggaacaccg gcccgccgtc gcggcagctg cttcacccct ctctctgcag ccatggggct   1140

ccctcgtgga cctctcgcgt ctctcctcct tctccaggtt tgctggctgc agtgcgcggc   1200

ctccgagccg tgccgggcgg tcttcaggga ggctgaagtg accttggagg cgggaggcgc   1260

ggagcaggag cccggccagg cgctggggaa agtattcatg ggctgccctg ggcaagagcc   1320

agctctgttt agcactgata atgatgactt cactgtgcgg aatggcgaga cagtccagga   1380

aagaaggtca ctgaaggaaa ggaatccatt gaagatcttc ccatccaaac gtatcttacg   1440

aagacacaag agagattggg tggttgctcc aatatctgtc cctgaaaatg gcaagggtcc   1500

cttcccccag agactgaatc agctcaagtc taataaagat agagacacca agattttcta   1560

cagcatcacg gggccggggg cagacagccc ccctgagggt gtcttcgctg tagagaagga   1620

gacaggctgg ttgttgttga ataagccact ggaccgggag gagattgcca agtatgagct   1680

ctttggccac gctgtgtcag agaatggtgc ctcagtggag gaccccatga acatctccat   1740

catcgtgacc gaccagaatg accacaagcc caagtttacc caggacacct tccgagggag   1800

tgtcttagag ggagtcctac caggtacttc tgtgatgcag gtgacagcca cggatgagga   1860

tgatgccatc tacacctaca atggggtggt tgcttactcc atccatagcc aagaaccaaa   1920

ggacccacac gacctcatgt tcaccattca ccggagcaca ggcaccatca gcgtcatctc   1980

cagtggcctg gaccgggaaa aagtccctga gtacacactg accatccagg ccacagacat   2040

ggatggggac ggctccacca ccacggcagt ggcagtagtg gagatccttg atgccaatga   2100

caatgctccc atgtttgacc cccagaagta cgaggcccat gtgcctgaga atgcagtggg   2160

ccatgaggtg cagaggctga cggtcactga tctggacgcc cccaactcac cagcgtggcg   2220

tgccacctac cttatcatgg gcggtgacga cggggaccat tttaccatca ccacccaccc   2280

tgagagcaac cagggcatcc tgacaaccag gaagggtttg gattttgagg ccaaaaacca   2340

gcacaccctg tacgttgaag tgaccaacga ggcccctttt gtgctgaagc tcccaacctc   2400

cacagccacc atagtggtcc acgtggagga tgtgaatgag gcacctgtgt ttgtcccacc   2460

ctccaaagtc gttgaggtcc aggagggcat ccccactggg gagcctgtgt gtgtctacac   2520

tgcagaagac cctgacaagg agaatcaaaa gatcagctac cgcatcctga gagacccagc   2580

agggtggcta gccatggacc cagacagtgg gcaggtcaca gctgtgggca ccctcgaccg   2640

tgaggatgag cagtttgtga ggaacaacat ctatgaagtc atggtcttgg ccatggacaa   2700

tggaagccct cccaccactg gcacgggaac ccttctgcta acactgattg atgtcaatga   2760

ccatggccca gtccctgagc cccgtcagat caccatctgc aaccaaagcc ctgtgcgcca   2820

ggtgctgaac atcacggaca aggacctgtc tccccacacc tcccctttcc aggcccagct   2880

cacagatgac tcagacatct actggacggc agaggtcaac gaggaaggtg acacagtggt   2940

cttgtccctg aagaagttcc tgaagcagga tacatatgac gtgcaccttt ctctgtctga   3000

ccatggcaac aaagagcagc tgacggtgat cagggccact gtgtgcgact gccatggcca   3060

tgtcgaaacc tgccctggac cctggaaggg aggtttcatc ctccctgtgc tgggggctgt   3120

cctggctctg ctgttcctcc tgctggtgct gcttttgttg gtgagaaaga agcggaagat   3180

caaggagccc ctcctactcc cagaagatga cacccgtgac aacgtcttct actatggcga   3240

agaggggggt ggcgaagagg accaggacta tgacatcacc cagctccacc gaggtctgga   3300

ggccaggccg gaggtggttc tccgcaatga cgtggcacca accatcatcc cgacacccat   3360

gtaccgtcct cggccagcca acccagatga aatcggcaac tttataattg agaacctgaa   3420

ggcggctaac acagacccca cagccccgcc ctacgacacc ctcttggtgt tcgactatga   3480

gggcagcggc tccgacgccg cgtccctgag ctccctcacc tcctccgcct ccgaccaaga   3540

ccaagattac gattatctga acgagtgggg cagccgcttc aagaagctgg cagacatgta   3600

cggtggcggg gaggacgact aggcggcctg cctgcagggc tggggaccaa acgtcaggcc   3660

acagagcatc tccaaggggt ctcagttccc ccttcagctg aggacttcgg agcttgtcag   3720

gaagtggccg tagcaacttg gcggagacag gctatgagtc tgacgttaga gtggtggctt   3780

ccttagcctt tcaggatgga ggaatgtggg cagtttgact tcagcactga aaacctctcc   3840

acctgggcca gggttgcctc agaggccaag tttccagaag cctcttacct gccgtaaaat   3900

gctcaaccct gtgtcctggg cctgggcctg ctgtgactga cctacagtgg actttctctc   3960

tggaatggaa ccttcttagg cctcctggtg caacttaatt ttttttttta atgctatctt   4020

caaaacgtta gagaaagttc ttcaaaagtg cagcccagag ctgctgggcc cactggccgt   4080

cctgcatttc tggtttccag accccaatgc ctcccattcg gatggatctc tgcgttttta   4140

tactgagtgt gcctaggttg ccccttattt tttattttcc ctgttgcgtt gctatagatg   4200

aagggtgagg acaatcgtgt atatgtacta gaactttttt attaaagaaa cttttcccag   4260

aggtgcctgg ggagtg                                                   4276


<210>  1059
<211>  482
<212>  PRT
<213>  Human

<400>  1059

Met Ala Ala Val Arg Met Leu Arg Thr Trp Ser Arg Asn Ala Gly Lys 
1               5                   10                  15      


Leu Ile Cys Val Arg Tyr Phe Gln Thr Cys Gly Asn Val His Val Leu 
            20                  25                  30          


Lys Pro Asn Tyr Val Cys Phe Phe Gly Tyr Pro Ser Phe Lys Tyr Ser 
        35                  40                  45              


His Pro His His Phe Leu Lys Thr Thr Ala Ala Leu Arg Gly Gln Val 
    50                  55                  60                  


Val Gln Phe Lys Leu Ser Asp Ile Gly Glu Gly Ile Arg Glu Val Thr 
65                  70                  75                  80  


Val Lys Glu Trp Tyr Val Lys Glu Gly Asp Thr Val Ser Gln Phe Asp 
                85                  90                  95      


Ser Ile Cys Glu Val Gln Ser Asp Lys Ala Ser Val Thr Ile Thr Ser 
            100                 105                 110         


Arg Tyr Asp Gly Val Ile Lys Lys Leu Tyr Tyr Asn Leu Asp Asp Ile 
        115                 120                 125             


Ala Tyr Val Gly Lys Pro Leu Val Asp Ile Glu Thr Glu Ala Leu Lys 
    130                 135                 140                 


Asp Ser Glu Glu Asp Val Val Glu Thr Pro Ala Val Ser His Asp Glu 
145                 150                 155                 160 


His Thr His Gln Glu Ile Lys Gly Arg Lys Thr Leu Ala Thr Pro Ala 
                165                 170                 175     


Val Arg Arg Leu Ala Met Glu Asn Asn Ile Lys Leu Ser Glu Val Val 
            180                 185                 190         


Gly Ser Gly Lys Asp Gly Arg Ile Leu Lys Glu Asp Ile Leu Asn Tyr 
        195                 200                 205             


Leu Glu Lys Gln Thr Gly Ala Ile Leu Pro Pro Ser Pro Lys Val Glu 
    210                 215                 220                 


Ile Met Pro Pro Pro Pro Lys Pro Lys Asp Met Thr Val Pro Ile Leu 
225                 230                 235                 240 


Val Ser Lys Pro Pro Val Phe Thr Gly Lys Asp Lys Thr Glu Pro Ile 
                245                 250                 255     


Lys Gly Phe Gln Lys Ala Met Val Lys Thr Met Ser Ala Ala Leu Lys 
            260                 265                 270         


Ile Pro His Phe Gly Tyr Cys Asp Glu Ile Asp Leu Thr Glu Leu Val 
        275                 280                 285             


Lys Leu Arg Glu Glu Leu Lys Pro Ile Ala Phe Ala Arg Gly Ile Lys 
    290                 295                 300                 


Leu Ser Phe Met Pro Phe Phe Leu Lys Ala Ala Ser Leu Gly Leu Leu 
305                 310                 315                 320 


Gln Phe Pro Ile Leu Asn Ala Ser Val Asp Glu Asn Cys Gln Asn Ile 
                325                 330                 335     


Thr Tyr Lys Ala Ser His Asn Ile Gly Ile Ala Met Asp Thr Glu Gln 
            340                 345                 350         


Gly Leu Ile Val Pro Asn Val Lys Asn Val Gln Ile Cys Ser Ile Phe 
        355                 360                 365             


Asp Ile Ala Thr Glu Leu Asn Arg Leu Gln Lys Leu Gly Ser Val Gly 
    370                 375                 380                 


Gln Leu Ser Thr Thr Asp Leu Thr Gly Gly Thr Phe Thr Leu Ser Asn 
385                 390                 395                 400 


Ile Gly Ser Ile Gly Gly Thr Phe Ala Lys Pro Val Ile Met Pro Pro 
                405                 410                 415     


Glu Val Ala Ile Gly Ala Leu Gly Ser Ile Lys Ala Ile Pro Arg Phe 
            420                 425                 430         


Asn Gln Lys Gly Glu Val Tyr Lys Ala Gln Ile Met Asn Val Ser Trp 
        435                 440                 445             


Ser Ala Asp His Arg Val Ile Asp Gly Ala Thr Met Ser Arg Phe Ser 
    450                 455                 460                 


Asn Leu Trp Lys Ser Tyr Leu Glu Asn Pro Ala Phe Met Leu Leu Asp 
465                 470                 475                 480 


Leu Lys 
        


<210>  1060
<211>  647
<212>  PRT
<213>  Human

<400>  1060

Met Trp Arg Val Cys Ala Arg Arg Ala Gln Asn Val Ala Pro Trp Ala 
1               5                   10                  15      


Gly Leu Glu Ala Arg Trp Thr Ala Leu Gln Glu Val Pro Gly Thr Pro 
            20                  25                  30          


Arg Val Thr Ser Arg Ser Gly Pro Ala Pro Ala Arg Arg Asn Ser Val 
        35                  40                  45              


Thr Thr Gly Tyr Gly Gly Val Arg Ala Leu Cys Gly Trp Thr Pro Ser 
    50                  55                  60                  


Ser Gly Ala Thr Pro Arg Asn Arg Leu Leu Leu Gln Leu Leu Gly Ser 
65                  70                  75                  80  


Pro Gly Arg Arg Tyr Tyr Ser Leu Pro Pro His Gln Lys Val Pro Leu 
                85                  90                  95      


Pro Ser Leu Ser Pro Thr Met Gln Ala Gly Thr Ile Ala Arg Trp Glu 
            100                 105                 110         


Lys Lys Glu Gly Asp Lys Ile Asn Glu Gly Asp Leu Ile Ala Glu Val 
        115                 120                 125             


Glu Thr Asp Lys Ala Thr Val Gly Phe Glu Ser Leu Glu Glu Cys Tyr 
    130                 135                 140                 


Met Ala Lys Ile Leu Val Ala Glu Gly Thr Arg Asp Val Pro Ile Gly 
145                 150                 155                 160 


Ala Ile Ile Cys Ile Thr Val Gly Lys Pro Glu Asp Ile Glu Ala Phe 
                165                 170                 175     


Lys Asn Tyr Thr Leu Asp Ser Ser Ala Ala Pro Thr Pro Gln Ala Ala 
            180                 185                 190         


Pro Ala Pro Thr Pro Ala Ala Thr Ala Ser Pro Pro Thr Pro Ser Ala 
        195                 200                 205             


Gln Ala Pro Gly Ser Ser Tyr Pro Pro His Met Gln Val Leu Leu Pro 
    210                 215                 220                 


Ala Leu Ser Pro Thr Met Thr Met Gly Thr Val Gln Arg Trp Glu Lys 
225                 230                 235                 240 


Lys Val Gly Glu Lys Leu Ser Glu Gly Asp Leu Leu Ala Glu Ile Glu 
                245                 250                 255     


Thr Asp Lys Ala Thr Ile Gly Phe Glu Val Gln Glu Glu Gly Tyr Leu 
            260                 265                 270         


Ala Lys Ile Leu Val Pro Glu Gly Thr Arg Asp Val Pro Leu Gly Thr 
        275                 280                 285             


Pro Leu Cys Ile Ile Val Glu Lys Glu Ala Asp Ile Ser Ala Phe Ala 
    290                 295                 300                 


Asp Tyr Arg Pro Thr Glu Val Thr Asp Leu Lys Pro Gln Val Pro Pro 
305                 310                 315                 320 


Pro Thr Pro Pro Pro Val Ala Ala Val Pro Pro Thr Pro Gln Pro Leu 
                325                 330                 335     


Ala Pro Thr Pro Ser Ala Pro Cys Pro Ala Thr Pro Ala Gly Pro Lys 
            340                 345                 350         


Gly Arg Val Phe Val Ser Pro Leu Ala Lys Lys Leu Ala Val Glu Lys 
        355                 360                 365             


Gly Ile Asp Leu Thr Gln Val Lys Gly Thr Gly Pro Asp Gly Arg Ile 
    370                 375                 380                 


Thr Lys Lys Asp Ile Asp Ser Phe Val Pro Ser Lys Val Ala Pro Ala 
385                 390                 395                 400 


Pro Ala Ala Val Val Pro Pro Thr Gly Pro Gly Met Ala Pro Val Pro 
                405                 410                 415     


Thr Gly Val Phe Thr Asp Ile Pro Ile Ser Asn Ile Arg Arg Val Ile 
            420                 425                 430         


Ala Gln Arg Leu Met Gln Ser Lys Gln Thr Ile Pro His Tyr Tyr Leu 
        435                 440                 445             


Ser Ile Asp Val Asn Met Gly Glu Val Leu Leu Val Arg Lys Glu Leu 
    450                 455                 460                 


Asn Lys Ile Leu Glu Gly Arg Ser Lys Ile Ser Val Asn Asp Phe Ile 
465                 470                 475                 480 


Ile Lys Ala Ser Ala Leu Ala Cys Leu Lys Val Pro Glu Ala Asn Ser 
                485                 490                 495     


Ser Trp Met Asp Thr Val Ile Arg Gln Asn His Val Val Asp Val Ser 
            500                 505                 510         


Val Ala Val Ser Thr Pro Ala Gly Leu Ile Thr Pro Ile Val Phe Asn 
        515                 520                 525             


Ala His Ile Lys Gly Val Glu Thr Ile Ala Asn Asp Val Val Ser Leu 
    530                 535                 540                 


Ala Thr Lys Ala Arg Glu Gly Lys Leu Gln Pro His Glu Phe Gln Gly 
545                 550                 555                 560 


Gly Thr Phe Thr Ile Ser Asn Leu Gly Met Phe Gly Ile Lys Asn Phe 
                565                 570                 575     


Ser Ala Ile Ile Asn Pro Pro Gln Ala Cys Ile Leu Ala Ile Gly Ala 
            580                 585                 590         


Ser Glu Asp Lys Leu Val Pro Ala Asp Asn Glu Lys Gly Phe Asp Val 
        595                 600                 605             


Ala Ser Met Met Ser Val Thr Leu Ser Cys Asp His Arg Val Val Asp 
    610                 615                 620                 


Gly Ala Val Gly Ala Gln Trp Leu Ala Glu Phe Arg Lys Tyr Leu Glu 
625                 630                 635                 640 


Lys Pro Ile Thr Met Leu Leu 
                645         


<210>  1061
<211>  586
<212>  PRT
<213>  Human

<400>  1061

Met Pro Lys Pro Ile Asn Val Arg Val Thr Thr Met Asp Ala Glu Leu 
1               5                   10                  15      


Glu Phe Ala Ile Gln Pro Asn Thr Thr Gly Lys Gln Leu Phe Asp Gln 
            20                  25                  30          


Val Val Lys Thr Ile Gly Leu Arg Glu Val Trp Tyr Phe Gly Leu His 
        35                  40                  45              


Tyr Val Asp Asn Lys Gly Phe Pro Thr Trp Leu Lys Leu Asp Lys Lys 
    50                  55                  60                  


Val Ser Ala Gln Glu Val Arg Lys Glu Asn Pro Leu Gln Phe Lys Phe 
65                  70                  75                  80  


Arg Ala Lys Phe Tyr Pro Glu Asp Val Ala Glu Glu Leu Ile Gln Asp 
                85                  90                  95      


Ile Thr Gln Lys Leu Phe Phe Leu Gln Val Lys Glu Gly Ile Leu Ser 
            100                 105                 110         


Asp Glu Ile Tyr Cys Pro Pro Glu Thr Ala Val Leu Leu Gly Ser Tyr 
        115                 120                 125             


Ala Val Gln Ala Lys Phe Gly Asp Tyr Asn Lys Glu Val His Lys Ser 
    130                 135                 140                 


Gly Tyr Leu Ser Ser Glu Arg Leu Ile Pro Gln Arg Val Met Asp Gln 
145                 150                 155                 160 


His Lys Leu Thr Arg Asp Gln Trp Glu Asp Arg Ile Gln Val Trp His 
                165                 170                 175     


Ala Glu His Arg Gly Met Leu Lys Asp Asn Ala Met Leu Glu Tyr Leu 
            180                 185                 190         


Lys Ile Ala Gln Asp Leu Glu Met Tyr Gly Ile Asn Tyr Phe Glu Ile 
        195                 200                 205             


Lys Asn Lys Lys Gly Thr Asp Leu Trp Leu Gly Val Asp Ala Leu Gly 
    210                 215                 220                 


Leu Asn Ile Tyr Glu Lys Asp Asp Lys Leu Thr Pro Lys Ile Gly Phe 
225                 230                 235                 240 


Pro Trp Ser Glu Ile Arg Asn Ile Ser Phe Asn Asp Lys Lys Phe Val 
                245                 250                 255     


Ile Lys Pro Ile Asp Lys Lys Ala Pro Asp Phe Val Phe Tyr Ala Pro 
            260                 265                 270         


Arg Leu Arg Ile Asn Lys Arg Ile Leu Gln Leu Cys Met Gly Asn His 
        275                 280                 285             


Glu Leu Tyr Met Arg Arg Arg Lys Pro Asp Thr Ile Glu Val Gln Gln 
    290                 295                 300                 


Met Lys Ala Gln Ala Arg Glu Glu Lys His Gln Lys Gln Leu Glu Arg 
305                 310                 315                 320 


Gln Gln Leu Glu Thr Glu Lys Lys Arg Arg Glu Thr Val Glu Arg Glu 
                325                 330                 335     


Lys Glu Gln Met Met Arg Glu Lys Glu Glu Leu Met Leu Arg Leu Gln 
            340                 345                 350         


Asp Tyr Glu Glu Lys Thr Lys Lys Ala Glu Arg Glu Leu Ser Glu Gln 
        355                 360                 365             


Ile Gln Arg Ala Leu Gln Leu Glu Glu Glu Arg Lys Arg Ala Gln Glu 
    370                 375                 380                 


Glu Ala Glu Arg Leu Glu Ala Asp Arg Met Ala Ala Leu Arg Ala Lys 
385                 390                 395                 400 


Glu Glu Leu Glu Arg Gln Ala Val Asp Gln Ile Lys Ser Gln Glu Gln 
                405                 410                 415     


Leu Ala Ala Glu Leu Ala Glu Tyr Thr Ala Lys Ile Ala Leu Leu Glu 
            420                 425                 430         


Glu Ala Arg Arg Arg Lys Glu Asp Glu Val Glu Glu Trp Gln His Arg 
        435                 440                 445             


Ala Lys Glu Ala Gln Asp Asp Leu Val Lys Thr Lys Glu Glu Leu His 
    450                 455                 460                 


Leu Val Met Thr Ala Pro Pro Pro Pro Pro Pro Pro Val Tyr Glu Pro 
465                 470                 475                 480 


Val Ser Tyr His Val Gln Glu Ser Leu Gln Asp Glu Gly Ala Glu Pro 
                485                 490                 495     


Thr Gly Tyr Ser Ala Glu Leu Ser Ser Glu Gly Ile Arg Asp Asp Arg 
            500                 505                 510         


Asn Glu Glu Lys Arg Ile Thr Glu Ala Glu Lys Asn Glu Arg Val Gln 
        515                 520                 525             


Arg Gln Leu Leu Thr Leu Ser Ser Glu Leu Ser Gln Ala Arg Asp Glu 
    530                 535                 540                 


Asn Lys Arg Thr His Asn Asp Ile Ile His Asn Glu Asn Met Arg Gln 
545                 550                 555                 560 


Gly Arg Asp Lys Tyr Lys Thr Leu Arg Gln Ile Arg Gln Gly Asn Thr 
                565                 570                 575     


Lys Gln Arg Ile Asp Glu Phe Glu Ala Leu 
            580                 585     


<210>  1062
<211>  126
<212>  PRT
<213>  Human

<400>  1062

Met Pro Glu Pro Thr Lys Ser Ala Pro Ala Pro Lys Lys Gly Ser Lys 
1               5                   10                  15      


Lys Ala Val Thr Lys Ala Gln Lys Lys Asp Gly Lys Lys Arg Lys Arg 
            20                  25                  30          


Ser Arg Lys Glu Ser Tyr Ser Val Tyr Val Tyr Lys Val Leu Lys Gln 
        35                  40                  45              


Val His Pro Asp Thr Gly Ile Ser Ser Lys Ala Met Gly Ile Met Asn 
    50                  55                  60                  


Ser Phe Val Asn Asp Ile Phe Glu Arg Ile Ala Gly Glu Ala Ser Arg 
65                  70                  75                  80  


Leu Ala His Tyr Asn Lys Arg Ser Thr Ile Thr Ser Arg Glu Ile Gln 
                85                  90                  95      


Thr Ala Val Arg Leu Leu Leu Pro Gly Glu Leu Ala Lys His Ala Val 
            100                 105                 110         


Ser Glu Gly Thr Lys Ala Val Thr Lys Tyr Thr Ser Ser Lys 
        115                 120                 125     


<210>  1063
<211>  372
<212>  PRT
<213>  Human

<400>  1063

Met Ser Lys Ser Glu Ser Pro Lys Glu Pro Glu Gln Leu Arg Lys Leu 
1               5                   10                  15      


Phe Ile Gly Gly Leu Ser Phe Glu Thr Thr Asp Glu Ser Leu Arg Ser 
            20                  25                  30          


His Phe Glu Gln Trp Gly Thr Leu Thr Asp Cys Val Val Met Arg Asp 
        35                  40                  45              


Pro Asn Thr Lys Arg Ser Arg Gly Phe Gly Phe Val Thr Tyr Ala Thr 
    50                  55                  60                  


Val Glu Glu Val Asp Ala Ala Met Asn Ala Arg Pro His Lys Val Asp 
65                  70                  75                  80  


Gly Arg Val Val Glu Pro Lys Arg Ala Val Ser Arg Glu Asp Ser Gln 
                85                  90                  95      


Arg Pro Gly Ala His Leu Thr Val Lys Lys Ile Phe Val Gly Gly Ile 
            100                 105                 110         


Lys Glu Asp Thr Glu Glu His His Leu Arg Asp Tyr Phe Glu Gln Tyr 
        115                 120                 125             


Gly Lys Ile Glu Val Ile Glu Ile Met Thr Asp Arg Gly Ser Gly Lys 
    130                 135                 140                 


Lys Arg Gly Phe Ala Phe Val Thr Phe Asp Asp His Asp Ser Val Asp 
145                 150                 155                 160 


Lys Ile Val Ile Gln Lys Tyr His Thr Val Asn Gly His Asn Cys Glu 
                165                 170                 175     


Val Arg Lys Ala Leu Ser Lys Gln Glu Met Ala Ser Ala Ser Ser Ser 
            180                 185                 190         


Gln Arg Gly Arg Ser Gly Ser Gly Asn Phe Gly Gly Gly Arg Gly Gly 
        195                 200                 205             


Gly Phe Gly Gly Asn Asp Asn Phe Gly Arg Gly Gly Asn Phe Ser Gly 
    210                 215                 220                 


Arg Gly Gly Phe Gly Gly Ser Arg Gly Gly Gly Gly Tyr Gly Gly Ser 
225                 230                 235                 240 


Gly Asp Gly Tyr Asn Gly Phe Gly Asn Asp Gly Gly Tyr Gly Gly Gly 
                245                 250                 255     


Gly Pro Gly Tyr Ser Gly Gly Ser Arg Gly Tyr Gly Ser Gly Gly Gln 
            260                 265                 270         


Gly Tyr Gly Asn Gln Gly Ser Gly Tyr Gly Gly Ser Gly Ser Tyr Asp 
        275                 280                 285             


Ser Tyr Asn Asn Gly Gly Gly Gly Gly Phe Gly Gly Gly Ser Gly Ser 
    290                 295                 300                 


Asn Phe Gly Gly Gly Gly Ser Tyr Asn Asp Phe Gly Asn Tyr Asn Asn 
305                 310                 315                 320 


Gln Ser Ser Asn Phe Gly Pro Met Lys Gly Gly Asn Phe Gly Gly Arg 
                325                 330                 335     


Ser Ser Gly Pro Tyr Gly Gly Gly Gly Gln Tyr Phe Ala Lys Pro Arg 
            340                 345                 350         


Asn Gln Gly Gly Tyr Gly Gly Ser Ser Ser Ser Ser Ser Tyr Gly Ser 
        355                 360                 365             


Gly Arg Arg Phe 
    370         


<210>  1064
<211>  341
<212>  PRT
<213>  Human

<400>  1064

Met Glu Arg Glu Lys Glu Gln Phe Arg Lys Leu Phe Ile Gly Gly Leu 
1               5                   10                  15      


Ser Phe Glu Thr Thr Glu Glu Ser Leu Arg Asn Tyr Tyr Glu Gln Trp 
            20                  25                  30          


Gly Lys Leu Thr Asp Cys Val Val Met Arg Asp Pro Ala Ser Lys Arg 
        35                  40                  45              


Ser Arg Gly Phe Gly Phe Val Thr Phe Ser Ser Met Ala Glu Val Asp 
    50                  55                  60                  


Ala Ala Met Ala Ala Arg Pro His Ser Ile Asp Gly Arg Val Val Glu 
65                  70                  75                  80  


Pro Lys Arg Ala Val Ala Arg Glu Glu Ser Gly Lys Pro Gly Ala His 
                85                  90                  95      


Val Thr Val Lys Lys Leu Phe Val Gly Gly Ile Lys Glu Asp Thr Glu 
            100                 105                 110         


Glu His His Leu Arg Asp Tyr Phe Glu Glu Tyr Gly Lys Ile Asp Thr 
        115                 120                 125             


Ile Glu Ile Ile Thr Asp Arg Gln Ser Gly Lys Lys Arg Gly Phe Gly 
    130                 135                 140                 


Phe Val Thr Phe Asp Asp His Asp Pro Val Asp Lys Ile Val Leu Gln 
145                 150                 155                 160 


Lys Tyr His Thr Ile Asn Gly His Asn Ala Glu Val Arg Lys Ala Leu 
                165                 170                 175     


Ser Arg Gln Glu Met Gln Glu Val Gln Ser Ser Arg Ser Gly Arg Gly 
            180                 185                 190         


Gly Asn Phe Gly Phe Gly Asp Ser Arg Gly Gly Gly Gly Asn Phe Gly 
        195                 200                 205             


Pro Gly Pro Gly Ser Asn Phe Arg Gly Gly Ser Asp Gly Tyr Gly Ser 
    210                 215                 220                 


Gly Arg Gly Phe Gly Asp Gly Tyr Asn Gly Tyr Gly Gly Gly Pro Gly 
225                 230                 235                 240 


Gly Gly Asn Phe Gly Gly Ser Pro Gly Tyr Gly Gly Gly Arg Gly Gly 
                245                 250                 255     


Tyr Gly Gly Gly Gly Pro Gly Tyr Gly Asn Gln Gly Gly Gly Tyr Gly 
            260                 265                 270         


Gly Gly Tyr Asp Asn Tyr Gly Gly Gly Asn Tyr Gly Ser Gly Asn Tyr 
        275                 280                 285             


Asn Asp Phe Gly Asn Tyr Asn Gln Gln Pro Ser Asn Tyr Gly Pro Met 
    290                 295                 300                 


Lys Ser Gly Asn Phe Gly Gly Ser Arg Asn Met Gly Gly Pro Tyr Gly 
305                 310                 315                 320 


Gly Gly Asn Tyr Gly Pro Gly Gly Ser Gly Gly Ser Gly Gly Tyr Gly 
                325                 330                 335     


Gly Arg Ser Arg Tyr 
            340     


<210>  1065
<211>  893
<212>  PRT
<213>  Human

<400>  1065

Met Ala Thr Glu Glu Phe Ile Ile Arg Ile Pro Pro Tyr His Tyr Ile 
1               5                   10                  15      


His Val Leu Asp Gln Asn Ser Asn Val Ser Arg Val Glu Val Gly Pro 
            20                  25                  30          


Lys Thr Tyr Ile Arg Gln Asp Asn Glu Arg Val Leu Phe Ala Pro Met 
        35                  40                  45              


Arg Met Val Thr Val Pro Pro Arg His Tyr Cys Thr Val Ala Asn Pro 
    50                  55                  60                  


Val Ser Arg Asp Ala Gln Gly Leu Val Leu Phe Asp Val Thr Gly Gln 
65                  70                  75                  80  


Val Arg Leu Arg His Ala Asp Leu Glu Ile Arg Leu Ala Gln Asp Pro 
                85                  90                  95      


Phe Pro Leu Tyr Pro Gly Glu Val Leu Glu Lys Asp Ile Thr Pro Leu 
            100                 105                 110         


Gln Val Val Leu Pro Asn Thr Ala Leu His Leu Lys Ala Leu Leu Asp 
        115                 120                 125             


Phe Glu Asp Lys Asp Gly Asp Lys Val Val Ala Gly Asp Glu Trp Leu 
    130                 135                 140                 


Phe Glu Gly Pro Gly Thr Tyr Ile Pro Arg Lys Glu Val Glu Val Val 
145                 150                 155                 160 


Glu Ile Ile Gln Ala Thr Ile Ile Arg Gln Asn Gln Ala Leu Arg Leu 
                165                 170                 175     


Arg Ala Arg Lys Glu Cys Trp Asp Arg Asp Gly Lys Glu Arg Val Thr 
            180                 185                 190         


Gly Glu Glu Trp Leu Val Thr Thr Val Gly Ala Tyr Leu Pro Ala Val 
        195                 200                 205             


Phe Glu Glu Val Leu Asp Leu Val Asp Ala Val Ile Leu Thr Glu Lys 
    210                 215                 220                 


Thr Ala Leu His Leu Arg Ala Arg Arg Asn Phe Arg Asp Phe Arg Gly 
225                 230                 235                 240 


Val Ser Arg Arg Thr Gly Glu Glu Trp Leu Val Thr Val Gln Asp Thr 
                245                 250                 255     


Glu Ala His Val Pro Asp Val His Glu Glu Val Leu Gly Val Val Pro 
            260                 265                 270         


Ile Thr Thr Leu Gly Pro His Asn Tyr Cys Val Ile Leu Asp Pro Val 
        275                 280                 285             


Gly Pro Asp Gly Lys Asn Gln Leu Gly Gln Lys Arg Val Val Lys Gly 
    290                 295                 300                 


Glu Lys Ser Phe Phe Leu Gln Pro Gly Glu Gln Leu Glu Gln Gly Ile 
305                 310                 315                 320 


Gln Asp Val Tyr Val Leu Ser Glu Gln Gln Gly Leu Leu Leu Arg Ala 
                325                 330                 335     


Leu Gln Pro Leu Glu Glu Gly Glu Asp Glu Glu Lys Val Ser His Gln 
            340                 345                 350         


Ala Gly Asp His Trp Leu Ile Arg Gly Pro Leu Glu Tyr Val Pro Ser 
        355                 360                 365             


Ala Lys Val Glu Val Val Glu Glu Arg Gln Ala Ile Pro Leu Asp Glu 
    370                 375                 380                 


Asn Glu Gly Ile Tyr Val Gln Asp Val Lys Thr Gly Lys Val Arg Ala 
385                 390                 395                 400 


Val Ile Gly Ser Thr Tyr Met Leu Thr Gln Asp Glu Val Leu Trp Glu 
                405                 410                 415     


Lys Glu Leu Pro Pro Gly Val Glu Glu Leu Leu Asn Lys Gly Gln Asp 
            420                 425                 430         


Pro Leu Ala Asp Arg Gly Glu Lys Asp Thr Ala Lys Ser Leu Gln Pro 
        435                 440                 445             


Leu Ala Pro Arg Asn Lys Thr Arg Val Val Ser Tyr Arg Val Pro His 
    450                 455                 460                 


Asn Ala Ala Val Gln Val Tyr Asp Tyr Arg Glu Lys Arg Ala Arg Val 
465                 470                 475                 480 


Val Phe Gly Pro Glu Leu Val Ser Leu Gly Pro Glu Glu Gln Phe Thr 
                485                 490                 495     


Val Leu Ser Leu Ser Ala Gly Arg Pro Lys Arg Pro His Ala Arg Arg 
            500                 505                 510         


Ala Leu Cys Leu Leu Leu Gly Pro Asp Phe Phe Thr Asp Val Ile Thr 
        515                 520                 525             


Ile Glu Thr Ala Asp His Ala Arg Leu Gln Leu Gln Leu Ala Tyr Asn 
    530                 535                 540                 


Trp His Phe Glu Val Asn Asp Arg Lys Asp Pro Gln Glu Thr Ala Lys 
545                 550                 555                 560 


Leu Phe Ser Val Pro Asp Phe Val Gly Asp Ala Cys Lys Ala Ile Ala 
                565                 570                 575     


Ser Arg Val Arg Gly Ala Val Ala Ser Val Thr Phe Asp Asp Phe His 
            580                 585                 590         


Lys Asn Ser Ala Arg Ile Ile Arg Thr Ala Val Phe Gly Phe Glu Thr 
        595                 600                 605             


Ser Glu Ala Lys Gly Pro Asp Gly Met Ala Leu Pro Arg Pro Arg Asp 
    610                 615                 620                 


Gln Ala Val Phe Pro Gln Asn Gly Leu Val Val Ser Ser Val Asp Val 
625                 630                 635                 640 


Gln Ser Val Glu Pro Val Asp Gln Arg Thr Arg Asp Ala Leu Gln Arg 
                645                 650                 655     


Ser Val Gln Leu Ala Ile Glu Ile Thr Thr Asn Ser Gln Glu Ala Ala 
            660                 665                 670         


Ala Lys His Glu Ala Gln Arg Leu Glu Gln Glu Ala Arg Gly Arg Leu 
        675                 680                 685             


Glu Arg Gln Lys Ile Leu Asp Gln Ser Glu Ala Glu Lys Ala Arg Lys 
    690                 695                 700                 


Glu Leu Leu Glu Leu Glu Ala Leu Ser Met Ala Val Glu Ser Thr Gly 
705                 710                 715                 720 


Thr Ala Lys Ala Glu Ala Glu Ser Arg Ala Glu Ala Ala Arg Ile Glu 
                725                 730                 735     


Gly Glu Gly Ser Val Leu Gln Ala Lys Leu Lys Ala Gln Ala Leu Ala 
            740                 745                 750         


Ile Glu Thr Glu Ala Glu Leu Gln Arg Val Gln Lys Val Arg Glu Leu 
        755                 760                 765             


Glu Leu Val Tyr Ala Arg Ala Gln Leu Glu Leu Glu Val Ser Lys Ala 
    770                 775                 780                 


Gln Gln Leu Ala Glu Val Glu Val Lys Lys Phe Lys Gln Met Thr Glu 
785                 790                 795                 800 


Ala Ile Gly Pro Ser Thr Ile Arg Asp Leu Ala Val Ala Gly Pro Glu 
                805                 810                 815     


Met Gln Val Lys Leu Leu Gln Ser Leu Gly Leu Lys Ser Thr Leu Ile 
            820                 825                 830         


Thr Asp Gly Ser Thr Pro Ile Asn Leu Phe Asn Thr Ala Phe Gly Leu 
        835                 840                 845             


Leu Gly Met Gly Pro Glu Gly Gln Pro Leu Gly Arg Arg Val Ala Ser 
    850                 855                 860                 


Gly Pro Ser Pro Gly Glu Gly Ile Ser Pro Gln Ser Ala Gln Ala Pro 
865                 870                 875                 880 


Gln Ala Pro Gly Asp Asn His Val Val Pro Val Leu Arg 
                885                 890             


<210>  1066
<211>  317
<212>  PRT
<213>  Human

<400>  1066

Met Pro Arg Glu Asp Arg Ala Thr Trp Lys Ser Asn Tyr Phe Leu Lys 
1               5                   10                  15      


Ile Ile Gln Leu Leu Asp Asp Tyr Pro Lys Cys Phe Ile Val Gly Ala 
            20                  25                  30          


Asp Asn Val Gly Ser Lys Gln Met Gln Gln Ile Arg Met Ser Leu Arg 
        35                  40                  45              


Gly Lys Ala Val Val Leu Met Gly Lys Asn Thr Met Met Arg Lys Ala 
    50                  55                  60                  


Ile Arg Gly His Leu Glu Asn Asn Pro Ala Leu Glu Lys Leu Leu Pro 
65                  70                  75                  80  


His Ile Arg Gly Asn Val Gly Phe Val Phe Thr Lys Glu Asp Leu Thr 
                85                  90                  95      


Glu Ile Arg Asp Met Leu Leu Ala Asn Lys Val Pro Ala Ala Ala Arg 
            100                 105                 110         


Ala Gly Ala Ile Ala Pro Cys Glu Val Thr Val Pro Ala Gln Asn Thr 
        115                 120                 125             


Gly Leu Gly Pro Glu Lys Thr Ser Phe Phe Gln Ala Leu Gly Ile Thr 
    130                 135                 140                 


Thr Lys Ile Ser Arg Gly Thr Ile Glu Ile Leu Ser Asp Val Gln Leu 
145                 150                 155                 160 


Ile Lys Thr Gly Asp Lys Val Gly Ala Ser Glu Ala Thr Leu Leu Asn 
                165                 170                 175     


Met Leu Asn Ile Ser Pro Phe Ser Phe Gly Leu Val Ile Gln Gln Val 
            180                 185                 190         


Phe Asp Asn Gly Ser Ile Tyr Asn Pro Glu Val Leu Asp Ile Thr Glu 
        195                 200                 205             


Glu Thr Leu His Ser Arg Phe Leu Glu Gly Val Arg Asn Val Ala Ser 
    210                 215                 220                 


Val Cys Leu Gln Ile Gly Tyr Pro Thr Val Ala Ser Val Pro His Ser 
225                 230                 235                 240 


Ile Ile Asn Gly Tyr Lys Arg Val Leu Ala Leu Ser Val Glu Thr Asp 
                245                 250                 255     


Tyr Thr Phe Pro Leu Ala Glu Lys Val Lys Ala Phe Leu Ala Asp Pro 
            260                 265                 270         


Ser Ala Phe Val Ala Ala Ala Pro Val Ala Ala Ala Thr Thr Ala Ala 
        275                 280                 285             


Pro Ala Ala Ala Ala Ala Pro Ala Lys Val Glu Ala Lys Glu Glu Ser 
    290                 295                 300                 


Glu Glu Ser Asp Glu Asp Met Gly Phe Gly Leu Phe Asp 
305                 310                 315         


<210>  1067
<211>  114
<212>  PRT
<213>  Human

<400>  1067

Met Ala Ser Val Ser Glu Leu Ala Cys Ile Tyr Ser Ala Leu Ile Leu 
1               5                   10                  15      


His Asp Asp Glu Val Thr Val Thr Glu Asp Lys Ile Asn Ala Leu Ile 
            20                  25                  30          


Lys Ala Ala Gly Val Asn Val Glu Pro Phe Trp Pro Gly Leu Phe Ala 
        35                  40                  45              


Lys Ala Leu Ala Asn Val Asn Ile Gly Ser Leu Ile Cys Asn Val Gly 
    50                  55                  60                  


Ala Gly Gly Pro Ala Pro Ala Ala Gly Ala Ala Pro Ala Gly Gly Pro 
65                  70                  75                  80  


Ala Pro Ser Thr Ala Ala Ala Pro Ala Glu Glu Lys Lys Val Glu Ala 
                85                  90                  95      


Lys Lys Glu Glu Ser Glu Glu Ser Asp Asp Asp Met Gly Phe Gly Leu 
            100                 105                 110         


Phe Asp 
        


<210>  1068
<211>  115
<212>  PRT
<213>  Human

<400>  1068

Met Arg Tyr Val Ala Ser Tyr Leu Leu Ala Ala Leu Gly Gly Asn Ser 
1               5                   10                  15      


Ser Pro Ser Ala Lys Asp Ile Lys Lys Ile Leu Asp Ser Val Gly Ile 
            20                  25                  30          


Glu Ala Asp Asp Asp Arg Leu Asn Lys Val Ile Ser Glu Leu Asn Gly 
        35                  40                  45              


Lys Asn Ile Glu Asp Val Ile Ala Gln Gly Ile Gly Lys Leu Ala Ser 
    50                  55                  60                  


Val Pro Ala Gly Gly Ala Val Ala Val Ser Ala Ala Pro Gly Ser Ala 
65                  70                  75                  80  


Ala Pro Ala Ala Gly Ser Ala Pro Ala Ala Ala Glu Glu Lys Lys Asp 
                85                  90                  95      


Glu Lys Lys Glu Glu Ser Glu Glu Ser Asp Asp Asp Met Gly Phe Gly 
            100                 105                 110         


Leu Phe Asp 
        115 


<210>  1069
<211>  628
<212>  PRT
<213>  Human

<400>  1069

Met Glu Val Ser Ala Ala Lys Ala Pro Ser Ala Ala Asp Leu Ser Glu 
1               5                   10                  15      


Ile Glu Ile Lys Lys Glu Met Lys Lys Asp Pro Leu Thr Asn Lys Ala 
            20                  25                  30          


Pro Glu Lys Pro Leu His Glu Val Pro Ser Gly Asn Ser Leu Leu Ser 
        35                  40                  45              


Ser Glu Thr Ile Leu Arg Thr Asn Lys Arg Gly Glu Arg Arg Arg Arg 
    50                  55                  60                  


Arg Cys Gln Val Ala Phe Ser Tyr Leu Pro Gln Asn Asp Asp Glu Leu 
65                  70                  75                  80  


Glu Leu Lys Val Gly Asp Ile Ile Glu Val Val Gly Glu Val Glu Glu 
                85                  90                  95      


Gly Trp Trp Glu Gly Val Leu Asn Gly Lys Thr Gly Met Phe Pro Ser 
            100                 105                 110         


Asn Phe Ile Lys Glu Leu Ser Gly Glu Ser Asp Glu Leu Gly Ile Ser 
        115                 120                 125             


Gln Asp Glu Gln Leu Ser Lys Ser Ser Leu Arg Glu Thr Thr Gly Ser 
    130                 135                 140                 


Glu Ser Asp Gly Gly Asp Ser Ser Ser Thr Lys Ser Glu Gly Ala Asn 
145                 150                 155                 160 


Gly Thr Val Ala Thr Ala Ala Ile Gln Pro Lys Lys Val Lys Gly Val 
                165                 170                 175     


Gly Phe Gly Asp Ile Phe Lys Asp Lys Pro Ile Lys Leu Arg Pro Arg 
            180                 185                 190         


Ser Ile Glu Val Glu Asn Asp Phe Leu Pro Val Glu Lys Thr Ile Gly 
        195                 200                 205             


Lys Lys Leu Pro Ala Thr Thr Ala Thr Pro Asp Ser Ser Lys Thr Glu 
    210                 215                 220                 


Met Asp Ser Arg Thr Lys Ser Lys Asp Tyr Cys Lys Val Ile Phe Pro 
225                 230                 235                 240 


Tyr Glu Ala Gln Asn Asp Asp Glu Leu Thr Ile Lys Glu Gly Asp Ile 
                245                 250                 255     


Val Thr Leu Ile Asn Lys Asp Cys Ile Asp Val Gly Trp Trp Glu Gly 
            260                 265                 270         


Glu Leu Asn Gly Arg Arg Gly Val Phe Pro Asp Asn Phe Val Lys Leu 
        275                 280                 285             


Leu Pro Pro Asp Phe Glu Lys Glu Gly Asn Arg Pro Lys Lys Pro Pro 
    290                 295                 300                 


Pro Pro Ser Ala Pro Val Ile Lys Gln Gly Ala Gly Thr Thr Glu Arg 
305                 310                 315                 320 


Lys His Glu Ile Lys Lys Ile Pro Pro Glu Arg Pro Glu Met Leu Pro 
                325                 330                 335     


Asn Arg Thr Glu Glu Lys Glu Arg Pro Glu Arg Glu Pro Lys Leu Asp 
            340                 345                 350         


Leu Gln Lys Pro Ser Val Pro Ala Ile Pro Pro Lys Lys Pro Arg Pro 
        355                 360                 365             


Pro Lys Thr Asn Ser Leu Ser Arg Pro Gly Ala Leu Pro Pro Arg Arg 
    370                 375                 380                 


Pro Glu Arg Pro Val Gly Pro Leu Thr His Thr Arg Gly Asp Ser Pro 
385                 390                 395                 400 


Lys Ile Asp Leu Ala Gly Ser Ser Leu Ser Gly Ile Leu Asp Lys Asp 
                405                 410                 415     


Leu Ser Asp Arg Ser Asn Asp Ile Asp Leu Glu Gly Phe Asp Ser Val 
            420                 425                 430         


Val Ser Ser Thr Glu Lys Leu Ser His Pro Thr Thr Ser Arg Pro Lys 
        435                 440                 445             


Ala Thr Gly Arg Arg Pro Pro Ser Gln Ser Leu Thr Ser Ser Ser Leu 
    450                 455                 460                 


Ser Ser Pro Asp Ile Phe Asp Ser Pro Ser Pro Glu Glu Asp Lys Glu 
465                 470                 475                 480 


Glu His Ile Ser Leu Ala His Arg Gly Val Asp Ala Ser Lys Lys Thr 
                485                 490                 495     


Ser Lys Thr Val Thr Ile Ser Gln Val Ser Asp Asn Lys Ala Ser Leu 
            500                 505                 510         


Pro Pro Lys Pro Gly Thr Met Ala Ala Gly Gly Gly Gly Pro Ala Pro 
        515                 520                 525             


Leu Ser Ser Ala Ala Pro Ser Pro Leu Ser Ser Ser Leu Gly Thr Ala 
    530                 535                 540                 


Gly His Arg Ala Asn Ser Pro Ser Leu Phe Gly Thr Glu Gly Lys Pro 
545                 550                 555                 560 


Lys Met Glu Pro Ala Ala Ser Ser Gln Ala Ala Val Glu Glu Leu Arg 
                565                 570                 575     


Thr Gln Val Arg Glu Leu Arg Ser Ile Ile Glu Thr Met Lys Asp Gln 
            580                 585                 590         


Gln Lys Arg Glu Ile Lys Gln Leu Leu Ser Glu Leu Asp Glu Glu Lys 
        595                 600                 605             


Lys Ile Arg Leu Arg Leu Gln Met Glu Val Asn Asp Ile Lys Lys Ala 
    610                 615                 620                 


Leu Gln Ser Lys 
625             


<210>  1070
<211>  437
<212>  PRT
<213>  Human

<400>  1070

Met Thr Gln Phe Leu Pro Pro Asn Leu Leu Ala Leu Phe Ala Pro Arg 
1               5                   10                  15      


Asp Pro Ile Pro Tyr Leu Pro Pro Leu Glu Lys Leu Pro His Glu Lys 
            20                  25                  30          


His His Asn Gln Pro Tyr Cys Gly Ile Ala Pro Tyr Ile Arg Glu Phe 
        35                  40                  45              


Glu Asp Pro Arg Asp Ala Pro Pro Pro Thr Arg Ala Glu Thr Arg Glu 
    50                  55                  60                  


Glu Arg Met Glu Arg Lys Arg Arg Glu Lys Ile Glu Arg Arg Gln Gln 
65                  70                  75                  80  


Glu Val Glu Thr Glu Leu Lys Met Trp Asp Pro His Asn Asp Pro Asn 
                85                  90                  95      


Ala Gln Gly Asp Ala Phe Lys Thr Leu Phe Val Ala Arg Val Asn Tyr 
            100                 105                 110         


Asp Thr Thr Glu Ser Lys Leu Arg Arg Glu Phe Glu Val Tyr Gly Pro 
        115                 120                 125             


Ile Lys Arg Ile His Met Val Tyr Ser Lys Arg Ser Gly Lys Pro Arg 
    130                 135                 140                 


Gly Tyr Ala Phe Ile Glu Tyr Glu His Glu Arg Asp Met His Ser Ala 
145                 150                 155                 160 


Tyr Lys His Ala Asp Gly Lys Lys Ile Asp Gly Arg Arg Val Leu Val 
                165                 170                 175     


Asp Val Glu Arg Gly Arg Thr Val Lys Gly Trp Arg Pro Arg Arg Leu 
            180                 185                 190         


Gly Gly Gly Leu Gly Gly Thr Arg Arg Gly Gly Ala Asp Val Asn Ile 
        195                 200                 205             


Arg His Ser Gly Arg Asp Asp Thr Ser Arg Tyr Asp Glu Arg Pro Gly 
    210                 215                 220                 


Pro Ser Pro Leu Pro His Arg Asp Arg Asp Arg Asp Arg Glu Arg Glu 
225                 230                 235                 240 


Arg Arg Glu Arg Ser Arg Glu Arg Asp Lys Glu Arg Glu Arg Arg Arg 
                245                 250                 255     


Ser Arg Ser Arg Asp Arg Arg Arg Arg Ser Arg Ser Arg Asp Lys Glu 
            260                 265                 270         


Glu Arg Arg Arg Ser Arg Glu Arg Ser Lys Asp Lys Asp Arg Asp Arg 
        275                 280                 285             


Lys Arg Arg Ser Ser Arg Ser Arg Glu Arg Ala Arg Arg Glu Arg Glu 
    290                 295                 300                 


Arg Lys Glu Glu Leu Arg Gly Gly Gly Gly Asp Met Ala Glu Pro Ser 
305                 310                 315                 320 


Glu Ala Gly Asp Ala Pro Pro Asp Asp Gly Pro Pro Gly Glu Leu Gly 
                325                 330                 335     


Pro Asp Gly Pro Asp Gly Pro Glu Glu Lys Gly Arg Asp Arg Asp Arg 
            340                 345                 350         


Glu Arg Arg Arg Ser His Arg Ser Glu Arg Glu Arg Arg Arg Asp Arg 
        355                 360                 365             


Asp Arg Asp Arg Asp Arg Asp Arg Glu His Lys Arg Gly Glu Arg Gly 
    370                 375                 380                 


Ser Glu Arg Gly Arg Asp Glu Ala Arg Gly Gly Gly Gly Gly Gln Asp 
385                 390                 395                 400 


Asn Gly Leu Glu Gly Leu Gly Asn Asp Ser Arg Asp Met Tyr Met Glu 
                405                 410                 415     


Ser Glu Gly Gly Asp Gly Tyr Leu Ala Pro Glu Asn Gly Tyr Leu Met 
            420                 425                 430         


Glu Ala Ala Pro Glu 
        435         


<210>  1071
<211>  231
<212>  PRT
<213>  Human

<400>  1071

Met Thr Val Gly Lys Ser Ser Lys Met Leu Gln His Ile Asp Tyr Arg 
1               5                   10                  15      


Met Arg Cys Ile Leu Gln Asp Gly Arg Ile Phe Ile Gly Thr Phe Lys 
            20                  25                  30          


Ala Phe Asp Lys His Met Asn Leu Ile Leu Cys Asp Cys Asp Glu Phe 
        35                  40                  45              


Arg Lys Ile Lys Pro Lys Asn Ser Lys Gln Ala Glu Arg Glu Glu Lys 
    50                  55                  60                  


Arg Val Leu Gly Leu Val Leu Leu Arg Gly Glu Asn Leu Val Ser Met 
65                  70                  75                  80  


Thr Val Glu Gly Pro Pro Pro Lys Asp Thr Gly Ile Ala Arg Val Pro 
                85                  90                  95      


Leu Ala Gly Ala Ala Gly Gly Pro Gly Ile Gly Arg Ala Ala Gly Arg 
            100                 105                 110         


Gly Ile Pro Ala Gly Val Pro Met Pro Gln Ala Pro Ala Gly Leu Ala 
        115                 120                 125             


Gly Pro Val Arg Gly Val Gly Gly Pro Ser Gln Gln Val Met Thr Pro 
    130                 135                 140                 


Gln Gly Arg Gly Thr Val Ala Ala Ala Ala Ala Ala Ala Thr Ala Ser 
145                 150                 155                 160 


Ile Ala Gly Ala Pro Thr Gln Tyr Pro Pro Gly Arg Gly Gly Pro Pro 
                165                 170                 175     


Pro Pro Met Gly Arg Gly Ala Pro Pro Pro Gly Met Met Gly Pro Pro 
            180                 185                 190         


Pro Gly Met Arg Pro Pro Met Gly Pro Pro Met Gly Ile Pro Pro Gly 
        195                 200                 205             


Arg Gly Thr Pro Met Gly Met Pro Pro Pro Gly Met Arg Pro Pro Pro 
    210                 215                 220                 


Pro Gly Met Arg Gly Leu Leu 
225                 230     


<210>  1072
<211>  240
<212>  PRT
<213>  Human

<400>  1072

Met Thr Val Gly Lys Ser Ser Lys Met Leu Gln His Ile Asp Tyr Arg 
1               5                   10                  15      


Met Arg Cys Ile Leu Gln Asp Gly Arg Ile Phe Ile Gly Thr Phe Lys 
            20                  25                  30          


Ala Phe Asp Lys His Met Asn Leu Ile Leu Cys Asp Cys Asp Glu Phe 
        35                  40                  45              


Arg Lys Ile Lys Pro Lys Asn Ala Lys Gln Pro Glu Arg Glu Glu Lys 
    50                  55                  60                  


Arg Val Leu Gly Leu Val Leu Leu Arg Gly Glu Asn Leu Val Ser Met 
65                  70                  75                  80  


Thr Val Glu Gly Pro Pro Pro Lys Asp Thr Gly Ile Ala Arg Val Pro 
                85                  90                  95      


Leu Ala Gly Ala Ala Gly Gly Pro Gly Val Gly Arg Ala Ala Gly Arg 
            100                 105                 110         


Gly Val Pro Ala Gly Val Pro Ile Pro Gln Ala Pro Ala Gly Leu Ala 
        115                 120                 125             


Gly Pro Val Arg Gly Val Gly Gly Pro Ser Gln Gln Val Met Thr Pro 
    130                 135                 140                 


Gln Gly Arg Gly Thr Val Ala Ala Ala Ala Val Ala Ala Thr Ala Ser 
145                 150                 155                 160 


Ile Ala Gly Ala Pro Thr Gln Tyr Pro Pro Gly Arg Gly Thr Pro Pro 
                165                 170                 175     


Pro Pro Val Gly Arg Ala Thr Pro Pro Pro Gly Ile Met Ala Pro Pro 
            180                 185                 190         


Pro Gly Met Arg Pro Pro Met Gly Pro Pro Ile Gly Leu Pro Pro Ala 
        195                 200                 205             


Arg Gly Thr Pro Ile Gly Met Pro Pro Pro Gly Met Arg Pro Pro Pro 
    210                 215                 220                 


Pro Gly Ile Arg Gly Pro Pro Pro Pro Gly Met Arg Pro Pro Arg Pro 
225                 230                 235                 240 


<210>  1073
<211>  445
<212>  PRT
<213>  Human

<400>  1073

Met Met Phe Thr Glu Asp Gln Gly Val Asp Asp Arg Leu Leu Tyr Asp 
1               5                   10                  15      


Ile Val Phe Lys His Phe Lys Arg Asn Lys Val Glu Ile Ser Asn Ala 
            20                  25                  30          


Ile Lys Lys Thr Phe Pro Phe Leu Glu Gly Leu Arg Asp Arg Asp Leu 
        35                  40                  45              


Ile Thr Asn Lys Met Phe Glu Asp Ser Gln Asp Ser Cys Arg Asn Leu 
    50                  55                  60                  


Val Pro Val Gln Arg Val Val Tyr Asn Val Leu Ser Glu Leu Glu Lys 
65                  70                  75                  80  


Thr Phe Asn Leu Pro Val Leu Glu Ala Leu Phe Ser Asp Val Asn Met 
                85                  90                  95      


Gln Glu Tyr Pro Asp Leu Ile His Ile Tyr Lys Gly Phe Glu Asn Val 
            100                 105                 110         


Ile His Asp Lys Leu Pro Leu Gln Glu Ser Glu Glu Glu Glu Arg Glu 
        115                 120                 125             


Glu Arg Ser Gly Leu Gln Leu Ser Leu Glu Gln Gly Thr Gly Glu Asn 
    130                 135                 140                 


Ser Phe Arg Ser Leu Thr Trp Pro Pro Ser Gly Ser Pro Ser His Ala 
145                 150                 155                 160 


Gly Thr Thr Pro Pro Glu Asn Gly Leu Ser Glu His Pro Cys Glu Thr 
                165                 170                 175     


Glu Gln Ile Asn Ala Lys Arg Lys Asp Thr Thr Ser Asp Lys Asp Asp 
            180                 185                 190         


Ser Leu Gly Ser Gln Gln Thr Asn Glu Gln Cys Ala Gln Lys Ala Glu 
        195                 200                 205             


Pro Thr Glu Ser Cys Glu Gln Ile Ala Val Gln Val Asn Asn Gly Asp 
    210                 215                 220                 


Ala Gly Arg Glu Met Pro Cys Pro Leu Pro Cys Asp Glu Glu Ser Pro 
225                 230                 235                 240 


Glu Ala Glu Leu His Asn His Gly Ile Gln Ile Asn Ser Cys Ser Val 
                245                 250                 255     


Arg Leu Val Asp Ile Lys Lys Glu Lys Pro Phe Ser Asn Ser Lys Val 
            260                 265                 270         


Glu Cys Gln Ala Gln Ala Arg Thr His His Asn Gln Ala Ser Asp Ile 
        275                 280                 285             


Ile Val Ile Ser Ser Glu Asp Ser Glu Gly Ser Thr Asp Val Asp Glu 
    290                 295                 300                 


Pro Leu Glu Val Phe Ile Ser Ala Pro Arg Ser Glu Pro Val Ile Asn 
305                 310                 315                 320 


Asn Asp Asn Pro Leu Glu Ser Asn Asp Glu Lys Glu Gly Gln Glu Ala 
                325                 330                 335     


Thr Cys Ser Arg Pro Gln Ile Val Pro Glu Pro Met Asp Phe Arg Lys 
            340                 345                 350         


Leu Ser Thr Phe Arg Glu Ser Phe Lys Lys Arg Val Ile Gly Gln Asp 
        355                 360                 365             


His Asp Phe Ser Glu Ser Ser Glu Glu Glu Ala Pro Ala Glu Ala Ser 
    370                 375                 380                 


Ser Gly Ala Leu Arg Ser Lys His Gly Glu Lys Ala Pro Met Thr Ser 
385                 390                 395                 400 


Arg Ser Thr Ser Thr Trp Arg Ile Pro Ser Arg Lys Arg Arg Phe Ser 
                405                 410                 415     


Ser Ser Asp Phe Ser Asp Leu Ser Asn Gly Glu Glu Leu Gln Glu Thr 
            420                 425                 430         


Cys Ser Ser Ser Leu Arg Arg Gly Ser Gly Lys Glu Asp 
        435                 440                 445 


<210>  1074
<211>  2328
<212>  PRT
<213>  Human

<400>  1074

Met Thr Ser Ala Thr Glu Phe Glu Asn Val Gly Asn Gln Pro Pro Tyr 
1               5                   10                  15      


Ser Arg Ile Asn Ala Arg Trp Asp Ala Pro Asp Asp Glu Leu Asp Asn 
            20                  25                  30          


Asp Asn Ser Ser Ala Arg Leu Phe Glu Arg Ser Arg Ile Lys Ala Leu 
        35                  40                  45              


Ala Asp Glu Arg Glu Val Val Gln Lys Lys Thr Phe Thr Lys Trp Val 
    50                  55                  60                  


Asn Ser His Leu Ala Arg Val Ser Cys Arg Ile Thr Asp Leu Tyr Lys 
65                  70                  75                  80  


Asp Leu Arg Asp Gly Arg Met Leu Ile Lys Leu Leu Glu Val Leu Ser 
                85                  90                  95      


Gly Glu Met Leu Pro Lys Pro Thr Lys Gly Lys Met Arg Ile His Cys 
            100                 105                 110         


Leu Glu Asn Val Asp Lys Ala Leu Gln Phe Leu Lys Glu Gln Arg Val 
        115                 120                 125             


His Leu Glu Asn Met Gly Ser His Asp Ile Val Asp Gly Asn His Arg 
    130                 135                 140                 


Leu Val Leu Gly Leu Ile Trp Thr Ile Ile Leu Arg Phe Gln Ile Gln 
145                 150                 155                 160 


Asp Ile Val Val Gln Thr Gln Glu Gly Arg Glu Thr Arg Ser Ala Lys 
                165                 170                 175     


Asp Ala Leu Leu Leu Trp Cys Gln Met Lys Thr Ala Gly Tyr Pro His 
            180                 185                 190         


Val Asn Val Thr Asn Phe Thr Ser Ser Trp Lys Asp Gly Leu Ala Phe 
        195                 200                 205             


Asn Ala Leu Ile His Lys His Arg Pro Asp Leu Ile Asp Phe Asp Lys 
    210                 215                 220                 


Leu Lys Asp Ser Asn Ala Arg His Asn Leu Glu His Ala Phe Asn Val 
225                 230                 235                 240 


Ala Glu Arg Gln Leu Gly Ile Ile Pro Leu Leu Asp Pro Glu Asp Val 
                245                 250                 255     


Phe Thr Glu Asn Pro Asp Glu Lys Ser Ile Ile Thr Tyr Val Val Ala 
            260                 265                 270         


Phe Tyr His Tyr Phe Ser Lys Met Lys Val Leu Ala Val Glu Gly Lys 
        275                 280                 285             


Arg Val Gly Lys Val Ile Asp His Ala Ile Glu Thr Glu Lys Met Ile 
    290                 295                 300                 


Glu Lys Tyr Ser Gly Leu Ala Ser Asp Leu Leu Thr Trp Ile Glu Gln 
305                 310                 315                 320 


Thr Ile Thr Val Leu Asn Ser Arg Lys Phe Ala Asn Ser Leu Thr Gly 
                325                 330                 335     


Val Gln Gln Gln Leu Gln Ala Phe Ser Thr Tyr Arg Thr Val Glu Lys 
            340                 345                 350         


Pro Pro Lys Phe Gln Glu Lys Gly Asn Leu Glu Val Leu Leu Phe Thr 
        355                 360                 365             


Ile Gln Ser Arg Met Arg Ala Asn Asn Gln Lys Val Tyr Thr Pro His 
    370                 375                 380                 


Asp Gly Lys Leu Val Ser Asp Ile Asn Arg Ala Trp Glu Ser Leu Glu 
385                 390                 395                 400 


Glu Ala Glu Tyr Arg Arg Glu Leu Ala Leu Arg Asn Glu Leu Ile Arg 
                405                 410                 415     


Gln Glu Lys Leu Glu Gln Leu Ala Arg Arg Phe Asp Arg Lys Ala Ala 
            420                 425                 430         


Met Arg Glu Thr Trp Leu Ser Glu Asn Gln Arg Leu Val Ala Gln Asp 
        435                 440                 445             


Asn Phe Gly Tyr Asp Leu Ala Ala Val Glu Ala Ala Lys Lys Lys His 
    450                 455                 460                 


Glu Ala Ile Glu Thr Asp Thr Ala Ala Tyr Glu Glu Arg Val Arg Ala 
465                 470                 475                 480 


Leu Glu Asp Leu Ala Gln Glu Leu Glu Lys Glu Asn Tyr His Asp Gln 
                485                 490                 495     


Lys Arg Ile Thr Ala Arg Lys Asp Asn Ile Leu Arg Leu Trp Ser Tyr 
            500                 505                 510         


Leu Gln Glu Leu Leu Gln Ser Arg Arg Gln Arg Leu Glu Thr Thr Leu 
        515                 520                 525             


Ala Leu Gln Lys Leu Phe Gln Asp Met Leu His Ser Ile Asp Trp Met 
    530                 535                 540                 


Asp Glu Ile Lys Ala His Leu Leu Ser Ala Glu Phe Gly Lys His Leu 
545                 550                 555                 560 


Leu Glu Val Glu Asp Leu Leu Gln Lys His Lys Leu Met Glu Ala Asp 
                565                 570                 575     


Ile Ala Ile Gln Gly Asp Lys Val Lys Ala Ile Thr Ala Ala Thr Leu 
            580                 585                 590         


Lys Phe Thr Glu Gly Lys Gly Tyr Gln Pro Cys Asp Pro Gln Val Ile 
        595                 600                 605             


Gln Asp Arg Ile Ser His Leu Glu Gln Cys Phe Glu Glu Leu Ser Asn 
    610                 615                 620                 


Met Ala Ala Gly Arg Lys Ala Gln Leu Glu Gln Ser Lys Arg Leu Trp 
625                 630                 635                 640 


Lys Phe Phe Trp Glu Met Asp Glu Ala Glu Ser Trp Ile Lys Glu Lys 
                645                 650                 655     


Glu Gln Ile Tyr Ser Ser Leu Asp Tyr Gly Lys Asp Leu Thr Ser Val 
            660                 665                 670         


Leu Ile Leu Gln Arg Lys His Lys Ala Phe Glu Asp Glu Leu Arg Gly 
        675                 680                 685             


Leu Asp Ala His Leu Glu Gln Ile Phe Gln Glu Ala His Gly Met Val 
    690                 695                 700                 


Ala Arg Lys Gln Phe Gly His Pro Gln Ile Glu Ala Arg Ile Lys Glu 
705                 710                 715                 720 


Val Ser Ala Gln Trp Asp Gln Leu Lys Asp Leu Ala Ala Phe Cys Lys 
                725                 730                 735     


Lys Asn Leu Gln Asp Ala Glu Asn Phe Phe Gln Phe Gln Gly Asp Ala 
            740                 745                 750         


Asp Asp Leu Lys Ala Trp Leu Gln Asp Ala His Arg Leu Leu Ser Gly 
        755                 760                 765             


Glu Asp Val Gly Gln Asp Glu Gly Ala Thr Arg Ala Leu Gly Lys Lys 
    770                 775                 780                 


His Lys Asp Phe Leu Glu Glu Leu Glu Glu Ser Arg Gly Val Met Glu 
785                 790                 795                 800 


His Leu Glu Gln Gln Ala Gln Gly Phe Pro Glu Glu Phe Arg Asp Ser 
                805                 810                 815     


Pro Asp Val Thr His Arg Leu Gln Ala Leu Arg Glu Leu Tyr Gln Gln 
            820                 825                 830         


Val Val Ala Gln Ala Asp Leu Arg Gln Gln Arg Leu Gln Glu Ala Leu 
        835                 840                 845             


Asp Leu Tyr Thr Val Phe Gly Glu Thr Asp Ala Cys Glu Leu Trp Met 
    850                 855                 860                 


Gly Glu Lys Glu Lys Trp Leu Ala Glu Met Glu Met Pro Asp Thr Leu 
865                 870                 875                 880 


Glu Asp Leu Glu Val Val Gln His Arg Phe Asp Ile Leu Asp Gln Glu 
                885                 890                 895     


Met Lys Thr Leu Met Thr Gln Ile Asp Gly Val Asn Leu Ala Ala Asn 
            900                 905                 910         


Ser Leu Val Glu Ser Gly His Pro Arg Ser Arg Glu Val Lys Gln Tyr 
        915                 920                 925             


Gln Asp His Leu Asn Thr Arg Trp Gln Ala Phe Gln Thr Leu Val Ser 
    930                 935                 940                 


Glu Arg Arg Glu Ala Val Asp Ser Ala Leu Arg Val His Asn Tyr Cys 
945                 950                 955                 960 


Val Asp Cys Glu Glu Thr Ser Lys Trp Ile Thr Asp Lys Thr Lys Val 
                965                 970                 975     


Val Glu Ser Thr Lys Asp Leu Gly Arg Asp Leu Ala Gly Ile Ile Ala 
            980                 985                 990         


Ile Gln Arg Lys Leu Ser Gly Leu  Glu Arg Asp Val Ala  Ala Ile Gln 
        995                 1000                 1005             


Ala Arg  Val Asp Ala Leu Glu  Arg Glu Ser Gln Gln  Leu Met Asp 
    1010                 1015                 1020             


Ser His  Pro Glu Gln Lys Glu  Asp Ile Gly Gln Arg  Gln Lys His 
    1025                 1030                 1035             


Leu Glu  Glu Leu Trp Gln Gly  Leu Gln Gln Ser Leu  Gln Gly Gln 
    1040                 1045                 1050             


Glu Asp  Leu Leu Gly Glu Val  Ser Gln Leu Gln Ala  Phe Leu Gln 
    1055                 1060                 1065             


Asp Leu  Asp Asp Phe Gln Ala  Trp Leu Ser Ile Thr  Gln Lys Ala 
    1070                 1075                 1080             


Val Ala  Ser Glu Asp Met Pro  Glu Ser Leu Pro Glu  Ala Glu Gln 
    1085                 1090                 1095             


Leu Leu  Gln Gln His Ala Gly  Ile Lys Asp Glu Ile  Asp Gly His 
    1100                 1105                 1110             


Gln Asp  Ser Tyr Gln Arg Val  Lys Glu Ser Gly Glu  Lys Val Ile 
    1115                 1120                 1125             


Gln Gly  Gln Thr Asp Pro Glu  Tyr Leu Leu Leu Gly  Gln Arg Leu 
    1130                 1135                 1140             


Glu Gly  Leu Asp Thr Gly Trp  Asn Ala Leu Gly Arg  Met Trp Glu 
    1145                 1150                 1155             


Ser Arg  Ser His Thr Leu Ala  Gln Cys Leu Gly Phe  Gln Glu Phe 
    1160                 1165                 1170             


Gln Lys  Asp Ala Lys Gln Ala  Glu Ala Ile Leu Ser  Asn Gln Glu 
    1175                 1180                 1185             


Tyr Thr  Leu Ala His Leu Glu  Pro Pro Asp Ser Leu  Glu Ala Ala 
    1190                 1195                 1200             


Glu Ala  Gly Ile Arg Lys Phe  Glu Asp Phe Leu Gly  Ser Met Glu 
    1205                 1210                 1215             


Asn Asn  Arg Asp Lys Val Leu  Ser Pro Val Asp Ser  Gly Asn Lys 
    1220                 1225                 1230             


Leu Val  Ala Glu Gly Asn Leu  Tyr Ser Asp Lys Ile  Lys Glu Lys 
    1235                 1240                 1245             


Val Gln  Leu Ile Glu Asp Arg  His Arg Lys Asn Asn  Glu Lys Ala 
    1250                 1255                 1260             


Gln Glu  Ala Ser Val Leu Leu  Arg Asp Asn Leu Glu  Leu Gln Asn 
    1265                 1270                 1275             


Phe Leu  Gln Asn Cys Gln Glu  Leu Thr Leu Trp Ile  Asn Asp Lys 
    1280                 1285                 1290             


Leu Leu  Thr Ser Gln Asp Val  Ser Tyr Asp Glu Ala  Arg Asn Leu 
    1295                 1300                 1305             


His Asn  Lys Trp Leu Lys His  Gln Ala Phe Val Ala  Glu Leu Ala 
    1310                 1315                 1320             


Ser His  Glu Gly Trp Leu Glu  Asn Ile Asp Ala Glu  Gly Lys Gln 
    1325                 1330                 1335             


Leu Met  Asp Glu Lys Pro Gln  Phe Thr Ala Leu Val  Ser Gln Lys 
    1340                 1345                 1350             


Leu Glu  Ala Leu His Arg Leu  Trp Asp Glu Leu Gln  Ala Thr Thr 
    1355                 1360                 1365             


Lys Glu  Lys Thr Gln His Leu  Ser Ala Ala Arg Ser  Ser Asp Leu 
    1370                 1375                 1380             


Arg Leu  Gln Thr His Ala Asp  Leu Asn Lys Trp Ile  Ser Ala Met 
    1385                 1390                 1395             


Glu Asp  Gln Leu Arg Ser Asp  Asp Pro Gly Lys Asp  Leu Thr Ser 
    1400                 1405                 1410             


Val Asn  Arg Met Leu Ala Lys  Leu Lys Arg Val Glu  Asp Gln Val 
    1415                 1420                 1425             


Asn Val  Arg Lys Glu Glu Leu  Gly Glu Leu Phe Ala  Gln Val Pro 
    1430                 1435                 1440             


Ser Met  Gly Glu Glu Gly Gly  Asp Ala Asp Leu Ser  Ile Glu Lys 
    1445                 1450                 1455             


Arg Phe  Leu Asp Leu Leu Glu  Pro Leu Gly Arg Arg  Lys Lys Gln 
    1460                 1465                 1470             


Leu Glu  Ser Ser Arg Ala Lys  Leu Gln Ile Ser Arg  Asp Leu Glu 
    1475                 1480                 1485             


Asp Glu  Thr Leu Trp Val Glu  Glu Arg Leu Pro Leu  Ala Gln Ser 
    1490                 1495                 1500             


Ala Asp  Tyr Gly Thr Asn Leu  Gln Thr Val Gln Leu  Phe Met Lys 
    1505                 1510                 1515             


Lys Asn  Gln Thr Leu Gln Asn  Glu Ile Leu Gly His  Thr Pro Arg 
    1520                 1525                 1530             


Val Glu  Asp Val Leu Gln Arg  Gly Gln Gln Leu Val  Glu Ala Ala 
    1535                 1540                 1545             


Glu Ile  Asp Cys Gln Asp Leu  Glu Glu Arg Leu Gly  His Leu Gln 
    1550                 1555                 1560             


Ser Ser  Trp Asp Arg Leu Arg  Glu Ala Ala Ala Gly  Arg Leu Gln 
    1565                 1570                 1575             


Arg Leu  Arg Asp Ala Asn Glu  Ala Gln Gln Tyr Tyr  Leu Asp Ala 
    1580                 1585                 1590             


Asp Glu  Ala Glu Ala Trp Ile  Gly Glu Gln Glu Leu  Tyr Val Ile 
    1595                 1600                 1605             


Ser Asp  Glu Ile Pro Lys Asp  Glu Glu Gly Ala Ile  Val Met Leu 
    1610                 1615                 1620             


Lys Arg  His Leu Arg Gln Gln  Arg Ala Val Glu Asp  Tyr Gly Arg 
    1625                 1630                 1635             


Asn Ile  Lys Gln Leu Ala Ser  Arg Ala Gln Gly Leu  Leu Ser Ala 
    1640                 1645                 1650             


Gly His  Pro Glu Gly Glu Gln  Ile Ile Arg Leu Gln  Gly Gln Val 
    1655                 1660                 1665             


Asp Lys  His Tyr Ala Gly Leu  Lys Asp Val Ala Glu  Glu Arg Lys 
    1670                 1675                 1680             


Arg Lys  Leu Glu Asn Met Tyr  His Leu Phe Gln Leu  Lys Arg Glu 
    1685                 1690                 1695             


Thr Asp  Asp Leu Glu Gln Trp  Ile Ser Glu Lys Glu  Leu Val Ala 
    1700                 1705                 1710             


Ser Ser  Pro Glu Met Gly Gln  Asp Phe Asp His Val  Thr Leu Leu 
    1715                 1720                 1725             


Arg Asp  Lys Phe Arg Asp Phe  Ala Arg Glu Thr Gly  Ala Ile Gly 
    1730                 1735                 1740             


Gln Glu  Arg Val Asp Asn Val  Asn Ala Phe Ile Glu  Arg Leu Ile 
    1745                 1750                 1755             


Asp Ala  Gly His Ser Glu Ala  Ala Thr Ile Ala Glu  Trp Lys Asp 
    1760                 1765                 1770             


Gly Leu  Asn Glu Met Trp Ala  Asp Leu Leu Glu Leu  Ile Asp Thr 
    1775                 1780                 1785             


Arg Met  Gln Leu Leu Ala Ala  Ser Tyr Asp Leu His  Arg Tyr Phe 
    1790                 1795                 1800             


Tyr Thr  Gly Ala Glu Ile Leu  Gly Leu Ile Asp Glu  Lys His Arg 
    1805                 1810                 1815             


Glu Leu  Pro Glu Asp Val Gly  Leu Asp Ala Ser Thr  Ala Glu Ser 
    1820                 1825                 1830             


Phe His  Arg Val His Thr Ala  Phe Glu Arg Glu Leu  His Leu Leu 
    1835                 1840                 1845             


Gly Val  Gln Val Gln Gln Phe  Gln Asp Val Ala Thr  Arg Leu Gln 
    1850                 1855                 1860             


Thr Ala  Tyr Ala Gly Glu Lys  Ala Glu Ala Ile Gln  Asn Lys Glu 
    1865                 1870                 1875             


Gln Glu  Val Ser Ala Ala Trp  Gln Ala Leu Leu Asp  Ala Cys Ala 
    1880                 1885                 1890             


Gly Arg  Arg Thr Gln Leu Val  Asp Thr Ala Asp Lys  Phe Arg Phe 
    1895                 1900                 1905             


Phe Ser  Met Ala Arg Asp Leu  Leu Ser Trp Met Glu  Ser Ile Ile 
    1910                 1915                 1920             


Arg Gln  Ile Glu Thr Gln Glu  Arg Pro Arg Asp Val  Ser Ser Val 
    1925                 1930                 1935             


Glu Leu  Leu Met Lys Tyr His  Gln Gly Ile Asn Ala  Glu Ile Glu 
    1940                 1945                 1950             


Thr Arg  Ser Lys Asn Phe Ser  Ala Cys Leu Glu Leu  Gly Glu Ser 
    1955                 1960                 1965             


Leu Leu  Gln Arg Gln His Gln  Ala Ser Glu Glu Ile  Arg Glu Lys 
    1970                 1975                 1980             


Leu Gln  Gln Val Met Ser Arg  Arg Lys Glu Met Asn  Glu Lys Trp 
    1985                 1990                 1995             


Glu Ala  Arg Trp Glu Arg Leu  Arg Met Leu Leu Glu  Val Cys Gln 
    2000                 2005                 2010             


Phe Ser  Arg Asp Ala Ser Val  Ala Glu Ala Trp Leu  Ile Ala Gln 
    2015                 2020                 2025             


Glu Pro  Tyr Leu Ala Ser Gly  Asp Phe Gly His Thr  Val Asp Ser 
    2030                 2035                 2040             


Val Glu  Lys Leu Ile Lys Arg  His Glu Ala Phe Glu  Lys Ser Thr 
    2045                 2050                 2055             


Ala Ser  Trp Ala Glu Arg Phe  Ala Ala Leu Glu Lys  Pro Thr Thr 
    2060                 2065                 2070             


Leu Glu  Leu Lys Glu Arg Gln  Ile Ala Glu Arg Pro  Ala Glu Glu 
    2075                 2080                 2085             


Thr Gly  Pro Gln Glu Glu Glu  Gly Glu Thr Ala Gly  Glu Ala Pro 
    2090                 2095                 2100             


Val Ser  His His Ala Ala Thr  Glu Arg Thr Ser Pro  Gly Glu Glu 
    2105                 2110                 2115             


Glu Gly  Thr Trp Pro Gln Asn  Leu Gln Gln Pro Pro  Pro Pro Gly 
    2120                 2125                 2130             


Gln His  Lys Asp Gly Gln Lys  Ser Thr Gly Asp Glu  Arg Pro Thr 
    2135                 2140                 2145             


Thr Glu  Pro Leu Phe Lys Val  Leu Asp Thr Pro Leu  Ser Glu Gly 
    2150                 2155                 2160             


Asp Glu  Pro Ala Thr Leu Pro  Ala Pro Arg Asp His  Gly Gln Ser 
    2165                 2170                 2175             


Val Gln  Met Glu Gly Tyr Leu  Gly Arg Lys His Asp  Leu Glu Gly 
    2180                 2185                 2190             


Pro Asn  Lys Lys Ala Ser Asn  Arg Ser Trp Asn Asn  Leu Tyr Cys 
    2195                 2200                 2205             


Val Leu  Arg Asn Ser Glu Leu  Thr Phe Tyr Lys Asp  Ala Lys Asn 
    2210                 2215                 2220             


Leu Ala  Leu Gly Met Pro Tyr  His Gly Glu Glu Pro  Leu Ala Leu 
    2225                 2230                 2235             


Arg His  Ala Ile Cys Glu Ile  Ala Ala Asn Tyr Lys  Lys Lys Lys 
    2240                 2245                 2250             


His Val  Phe Lys Leu Arg Leu  Ser Asn Gly Ser Glu  Trp Leu Phe 
    2255                 2260                 2265             


His Gly  Lys Asp Glu Glu Glu  Met Leu Ser Trp Leu  Gln Gly Val 
    2270                 2275                 2280             


Ser Thr  Ala Ile Asn Glu Ser  Gln Ser Ile Arg Val  Lys Ala Gln 
    2285                 2290                 2295             


Ser Leu  Pro Leu Pro Ser Leu  Ser Gly Pro Asp Ala  Ser Leu Gly 
    2300                 2305                 2310             


Lys Lys  Asp Lys Glu Lys Arg  Phe Ser Phe Phe Pro  Lys Lys Lys 
    2315                 2320                 2325             


<210>  1075
<211>  408
<212>  PRT
<213>  Human

<400>  1075

Met Ala Glu Asn Gly Asp Asn Glu Lys Met Ala Ala Leu Glu Ala Lys 
1               5                   10                  15      


Ile Cys His Gln Ile Glu Tyr Tyr Phe Gly Asp Phe Asn Leu Pro Arg 
            20                  25                  30          


Asp Lys Phe Leu Lys Glu Gln Ile Lys Leu Asp Glu Gly Trp Val Pro 
        35                  40                  45              


Leu Glu Ile Met Ile Lys Phe Asn Arg Leu Asn Arg Leu Thr Thr Asp 
    50                  55                  60                  


Phe Asn Val Ile Val Glu Ala Leu Ser Lys Ser Lys Ala Glu Leu Met 
65                  70                  75                  80  


Glu Ile Ser Glu Asp Lys Thr Lys Ile Arg Arg Ser Pro Ser Lys Pro 
                85                  90                  95      


Leu Pro Glu Val Thr Asp Glu Tyr Lys Asn Asp Val Lys Asn Arg Ser 
            100                 105                 110         


Val Tyr Ile Lys Gly Phe Pro Thr Asp Ala Thr Leu Asp Asp Ile Lys 
        115                 120                 125             


Glu Trp Leu Glu Asp Lys Gly Gln Val Leu Asn Ile Gln Met Arg Arg 
    130                 135                 140                 


Thr Leu His Lys Ala Phe Lys Gly Ser Ile Phe Val Val Phe Asp Ser 
145                 150                 155                 160 


Ile Glu Ser Ala Lys Lys Phe Val Glu Thr Pro Gly Gln Lys Tyr Lys 
                165                 170                 175     


Glu Thr Asp Leu Leu Ile Leu Phe Lys Asp Asp Tyr Phe Ala Lys Lys 
            180                 185                 190         


Asn Glu Glu Arg Lys Gln Asn Lys Val Glu Ala Lys Leu Arg Ala Lys 
        195                 200                 205             


Gln Glu Gln Glu Ala Lys Gln Lys Leu Glu Glu Asp Ala Glu Met Lys 
    210                 215                 220                 


Ser Leu Glu Glu Lys Ile Gly Cys Leu Leu Lys Phe Ser Gly Asp Leu 
225                 230                 235                 240 


Asp Asp Gln Thr Cys Arg Glu Asp Leu His Ile Leu Phe Ser Asn His 
                245                 250                 255     


Gly Glu Ile Lys Trp Ile Asp Phe Val Arg Gly Ala Lys Glu Gly Ile 
            260                 265                 270         


Ile Leu Phe Lys Glu Lys Ala Lys Glu Ala Leu Gly Lys Ala Lys Asp 
        275                 280                 285             


Ala Asn Asn Gly Asn Leu Gln Leu Arg Asn Lys Glu Val Thr Trp Glu 
    290                 295                 300                 


Val Leu Glu Gly Glu Val Glu Lys Glu Ala Leu Lys Lys Ile Ile Glu 
305                 310                 315                 320 


Asp Gln Gln Glu Ser Leu Asn Lys Trp Lys Ser Lys Gly Arg Arg Phe 
                325                 330                 335     


Lys Gly Lys Gly Lys Gly Asn Lys Ala Ala Gln Pro Gly Ser Gly Lys 
            340                 345                 350         


Gly Lys Val Gln Phe Gln Gly Lys Lys Thr Lys Phe Ala Ser Asp Asp 
        355                 360                 365             


Glu His Asp Glu His Asp Glu Asn Gly Ala Thr Gly Pro Val Lys Arg 
    370                 375                 380                 


Ala Arg Glu Glu Thr Asp Lys Glu Glu Pro Ala Ser Lys Gln Gln Lys 
385                 390                 395                 400 


Thr Glu Asn Gly Ala Gly Asp Gln 
                405             


<210>  1076
<211>  454
<212>  PRT
<213>  Human

<400>  1076

Met Pro Glu Phe Leu Glu Asp Pro Ser Val Leu Thr Lys Asp Lys Leu 
1               5                   10                  15      


Lys Ser Glu Leu Val Ala Asn Asn Val Thr Leu Pro Ala Gly Glu Gln 
            20                  25                  30          


Arg Lys Asp Val Tyr Val Gln Leu Tyr Leu Gln His Leu Thr Ala Arg 
        35                  40                  45              


Asn Arg Pro Pro Leu Pro Ala Gly Thr Asn Ser Lys Gly Pro Pro Asp 
    50                  55                  60                  


Phe Ser Ser Asp Glu Glu Arg Glu Pro Thr Pro Val Leu Gly Ser Gly 
65                  70                  75                  80  


Ala Ala Ala Ala Gly Arg Ser Arg Ala Ala Val Gly Arg Lys Ala Thr 
                85                  90                  95      


Lys Lys Thr Asp Lys Pro Arg Gln Glu Asp Lys Asp Asp Leu Asp Val 
            100                 105                 110         


Thr Glu Leu Thr Asn Glu Asp Leu Leu Asp Gln Leu Val Lys Tyr Gly 
        115                 120                 125             


Val Asn Pro Gly Pro Ile Val Gly Thr Thr Arg Lys Leu Tyr Glu Lys 
    130                 135                 140                 


Lys Leu Leu Lys Leu Arg Glu Gln Gly Thr Glu Ser Arg Ser Ser Thr 
145                 150                 155                 160 


Pro Leu Pro Thr Ile Ser Ser Ser Ala Glu Asn Thr Arg Gln Asn Gly 
                165                 170                 175     


Ser Asn Asp Ser Asp Arg Tyr Ser Asp Asn Glu Glu Asp Ser Lys Ile 
            180                 185                 190         


Glu Leu Lys Leu Glu Lys Arg Glu Pro Leu Lys Gly Arg Ala Lys Thr 
        195                 200                 205             


Pro Val Thr Leu Lys Gln Arg Arg Val Glu His Asn Gln Ser Tyr Ser 
    210                 215                 220                 


Gln Ala Gly Ile Thr Glu Thr Glu Trp Thr Ser Gly Ser Ser Lys Gly 
225                 230                 235                 240 


Gly Pro Leu Gln Ala Leu Thr Arg Glu Ser Thr Arg Gly Ser Arg Arg 
                245                 250                 255     


Thr Pro Arg Lys Arg Val Glu Thr Ser Glu His Phe Arg Ile Asp Gly 
            260                 265                 270         


Pro Val Ile Ser Glu Ser Thr Pro Ile Ala Glu Thr Ile Met Ala Ser 
        275                 280                 285             


Ser Asn Glu Ser Leu Val Val Asn Arg Val Thr Gly Asn Phe Lys His 
    290                 295                 300                 


Ala Ser Pro Ile Leu Pro Ile Thr Glu Phe Ser Asp Ile Pro Arg Arg 
305                 310                 315                 320 


Ala Pro Lys Lys Pro Leu Thr Arg Ala Glu Val Gly Glu Lys Thr Glu 
                325                 330                 335     


Glu Arg Arg Val Glu Arg Asp Ile Leu Lys Glu Met Phe Pro Tyr Glu 
            340                 345                 350         


Ala Ser Thr Pro Thr Gly Ile Ser Ala Ser Cys Arg Arg Pro Ile Lys 
        355                 360                 365             


Gly Ala Ala Gly Arg Pro Leu Glu Leu Ser Asp Phe Arg Met Glu Glu 
    370                 375                 380                 


Ser Phe Ser Ser Lys Tyr Val Pro Lys Tyr Val Pro Leu Ala Asp Val 
385                 390                 395                 400 


Lys Ser Glu Lys Thr Lys Lys Gly Arg Ser Ile Pro Val Trp Ile Lys 
                405                 410                 415     


Ile Leu Leu Phe Val Val Val Ala Val Phe Leu Phe Leu Val Tyr Gln 
            420                 425                 430         


Ala Met Glu Thr Asn Gln Val Asn Pro Phe Ser Asn Phe Leu His Val 
        435                 440                 445             


Asp Pro Arg Lys Ser Asn 
    450                 


<210>  1077
<211>  475
<212>  PRT
<213>  Human

<400>  1077

Met Ala Ser Ala Ala Arg Leu Thr Met Met Trp Glu Glu Val Thr Cys 
1               5                   10                  15      


Pro Ile Cys Leu Asp Pro Phe Val Glu Pro Val Ser Ile Glu Cys Gly 
            20                  25                  30          


His Ser Phe Cys Gln Glu Cys Ile Ser Gln Val Gly Lys Gly Gly Gly 
        35                  40                  45              


Ser Val Cys Pro Val Cys Arg Gln Arg Phe Leu Leu Lys Asn Leu Arg 
    50                  55                  60                  


Pro Asn Arg Gln Leu Ala Asn Met Val Asn Asn Leu Lys Glu Ile Ser 
65                  70                  75                  80  


Gln Glu Ala Arg Glu Gly Thr Gln Gly Glu Arg Cys Ala Val His Gly 
                85                  90                  95      


Glu Arg Leu His Leu Phe Cys Glu Lys Asp Gly Lys Ala Leu Cys Trp 
            100                 105                 110         


Val Cys Ala Gln Ser Arg Lys His Arg Asp His Ala Met Val Pro Leu 
        115                 120                 125             


Glu Glu Ala Ala Gln Glu Tyr Gln Glu Lys Leu Gln Val Ala Leu Gly 
    130                 135                 140                 


Glu Leu Arg Arg Lys Gln Glu Leu Ala Glu Lys Leu Glu Val Glu Ile 
145                 150                 155                 160 


Ala Ile Lys Arg Ala Asp Trp Lys Lys Thr Val Glu Thr Gln Lys Ser 
                165                 170                 175     


Arg Ile His Ala Glu Phe Val Gln Gln Lys Asn Phe Leu Val Glu Glu 
            180                 185                 190         


Glu Gln Arg Gln Leu Gln Glu Leu Glu Lys Asp Glu Arg Glu Gln Leu 
        195                 200                 205             


Arg Ile Leu Gly Glu Lys Glu Ala Lys Leu Ala Gln Gln Ser Gln Ala 
    210                 215                 220                 


Leu Gln Glu Leu Ile Ser Glu Leu Asp Arg Arg Cys His Ser Ser Ala 
225                 230                 235                 240 


Leu Glu Leu Leu Gln Glu Val Ile Ile Val Leu Glu Arg Ser Glu Ser 
                245                 250                 255     


Trp Asn Leu Lys Asp Leu Asp Ile Thr Ser Pro Glu Leu Arg Ser Val 
            260                 265                 270         


Cys His Val Pro Gly Leu Lys Lys Met Leu Arg Thr Cys Ala Val His 
        275                 280                 285             


Ile Thr Leu Asp Pro Asp Thr Ala Asn Pro Trp Leu Ile Leu Ser Glu 
    290                 295                 300                 


Asp Arg Arg Gln Val Arg Leu Gly Asp Thr Gln Gln Ser Ile Pro Gly 
305                 310                 315                 320 


Asn Glu Glu Arg Phe Asp Ser Tyr Pro Met Val Leu Gly Ala Gln His 
                325                 330                 335     


Phe His Ser Gly Lys His Tyr Trp Glu Val Asp Val Thr Gly Lys Glu 
            340                 345                 350         


Ala Trp Asp Leu Gly Val Cys Arg Asp Ser Val Arg Arg Lys Gly His 
        355                 360                 365             


Phe Leu Leu Ser Ser Lys Ser Gly Phe Trp Thr Ile Trp Leu Trp Asn 
    370                 375                 380                 


Lys Gln Lys Tyr Glu Ala Gly Thr Tyr Pro Gln Thr Pro Leu His Leu 
385                 390                 395                 400 


Gln Val Pro Pro Cys Gln Val Gly Ile Phe Leu Asp Tyr Glu Ala Gly 
                405                 410                 415     


Met Val Ser Phe Tyr Asn Ile Thr Asp His Gly Ser Leu Ile Tyr Ser 
            420                 425                 430         


Phe Ser Glu Cys Ala Phe Thr Gly Pro Leu Arg Pro Phe Phe Ser Pro 
        435                 440                 445             


Gly Phe Asn Asp Gly Gly Lys Asn Thr Ala Pro Leu Thr Leu Cys Pro 
    450                 455                 460                 


Leu Asn Ile Gly Ser Gln Gly Ser Thr Asp Tyr 
465                 470                 475 


<210>  1078
<211>  525
<212>  PRT
<213>  Human

<400>  1078

Met Glu Glu Ser Val Asn Gln Met Gln Pro Leu Asn Glu Lys Gln Ile 
1               5                   10                  15      


Ala Asn Ser Gln Asp Gly Tyr Val Trp Gln Val Thr Asp Met Asn Arg 
            20                  25                  30          


Leu His Arg Phe Leu Cys Phe Gly Ser Glu Gly Gly Thr Tyr Tyr Ile 
        35                  40                  45              


Lys Glu Gln Lys Leu Gly Leu Glu Asn Ala Glu Ala Leu Ile Arg Leu 
    50                  55                  60                  


Ile Glu Asp Gly Arg Gly Cys Glu Val Ile Gln Glu Ile Lys Ser Phe 
65                  70                  75                  80  


Ser Gln Glu Gly Arg Thr Thr Lys Gln Glu Pro Met Leu Phe Ala Leu 
                85                  90                  95      


Ala Ile Cys Ser Gln Cys Ser Asp Ile Ser Thr Lys Gln Ala Ala Phe 
            100                 105                 110         


Lys Ala Val Ser Glu Val Cys Arg Ile Pro Thr His Leu Phe Thr Phe 
        115                 120                 125             


Ile Gln Phe Lys Lys Asp Leu Lys Glu Ser Met Lys Cys Gly Met Trp 
    130                 135                 140                 


Gly Arg Ala Leu Arg Lys Ala Ile Ala Asp Trp Tyr Asn Glu Lys Gly 
145                 150                 155                 160 


Gly Met Ala Leu Ala Leu Ala Val Thr Lys Tyr Lys Gln Arg Asn Gly 
                165                 170                 175     


Trp Ser His Lys Asp Leu Leu Arg Leu Ser His Leu Lys Pro Ser Ser 
            180                 185                 190         


Glu Gly Leu Ala Ile Val Thr Lys Tyr Ile Thr Lys Gly Trp Lys Glu 
        195                 200                 205             


Val His Glu Leu Tyr Lys Glu Lys Ala Leu Ser Val Glu Thr Glu Lys 
    210                 215                 220                 


Leu Leu Lys Tyr Leu Glu Ala Val Glu Lys Val Lys Arg Thr Arg Asp 
225                 230                 235                 240 


Glu Leu Glu Val Ile His Leu Ile Glu Glu His Arg Leu Val Arg Glu 
                245                 250                 255     


His Leu Leu Thr Asn His Leu Lys Ser Lys Glu Val Trp Lys Ala Leu 
            260                 265                 270         


Leu Gln Glu Met Pro Leu Thr Ala Leu Leu Arg Asn Leu Gly Lys Met 
        275                 280                 285             


Thr Ala Asn Ser Val Leu Glu Pro Gly Asn Ser Glu Val Ser Leu Val 
    290                 295                 300                 


Cys Glu Lys Leu Cys Asn Glu Lys Leu Leu Lys Lys Ala Arg Ile His 
305                 310                 315                 320 


Pro Phe His Ile Leu Ile Ala Leu Glu Thr Tyr Lys Thr Gly His Gly 
                325                 330                 335     


Leu Arg Gly Lys Leu Lys Trp Arg Pro Asp Glu Glu Ile Leu Lys Ala 
            340                 345                 350         


Leu Asp Ala Ala Phe Tyr Lys Thr Phe Lys Thr Val Glu Pro Thr Gly 
        355                 360                 365             


Lys Arg Phe Leu Leu Ala Val Asp Val Ser Ala Ser Met Asn Gln Arg 
    370                 375                 380                 


Val Leu Gly Ser Ile Leu Asn Ala Ser Thr Val Ala Ala Ala Met Cys 
385                 390                 395                 400 


Met Val Val Thr Arg Thr Glu Lys Asp Ser Tyr Val Val Ala Phe Ser 
                405                 410                 415     


Asp Glu Met Val Pro Cys Pro Val Thr Thr Asp Met Thr Leu Gln Gln 
            420                 425                 430         


Val Leu Met Ala Met Ser Gln Ile Pro Ala Gly Gly Thr Asp Cys Ser 
        435                 440                 445             


Leu Pro Met Ile Trp Ala Gln Lys Thr Asn Thr Pro Ala Asp Val Phe 
    450                 455                 460                 


Ile Val Phe Thr Asp Asn Glu Thr Phe Ala Gly Gly Val His Pro Ala 
465                 470                 475                 480 


Ile Ala Leu Arg Glu Tyr Arg Lys Lys Met Asp Ile Pro Ala Lys Leu 
                485                 490                 495     


Ile Val Cys Gly Met Thr Ser Asn Gly Phe Thr Ile Ala Asp Pro Asp 
            500                 505                 510         


Asp Arg Ala Leu Gln Asn Thr Leu Leu Asn Lys Ser Phe 
        515                 520                 525 


<210>  1079
<211>  466
<212>  PRT
<213>  Human

<400>  1079

Met Ser Thr Arg Ser Val Ser Ser Ser Ser Tyr Arg Arg Met Phe Gly 
1               5                   10                  15      


Gly Pro Gly Thr Ala Ser Arg Pro Ser Ser Ser Arg Ser Tyr Val Thr 
            20                  25                  30          


Thr Ser Thr Arg Thr Tyr Ser Leu Gly Ser Ala Leu Arg Pro Ser Thr 
        35                  40                  45              


Ser Arg Ser Leu Tyr Ala Ser Ser Pro Gly Gly Val Tyr Ala Thr Arg 
    50                  55                  60                  


Ser Ser Ala Val Arg Leu Arg Ser Ser Val Pro Gly Val Arg Leu Leu 
65                  70                  75                  80  


Gln Asp Ser Val Asp Phe Ser Leu Ala Asp Ala Ile Asn Thr Glu Phe 
                85                  90                  95      


Lys Asn Thr Arg Thr Asn Glu Lys Val Glu Leu Gln Glu Leu Asn Asp 
            100                 105                 110         


Arg Phe Ala Asn Tyr Ile Asp Lys Val Arg Phe Leu Glu Gln Gln Asn 
        115                 120                 125             


Lys Ile Leu Leu Ala Glu Leu Glu Gln Leu Lys Gly Gln Gly Lys Ser 
    130                 135                 140                 


Arg Leu Gly Asp Leu Tyr Glu Glu Glu Met Arg Glu Leu Arg Arg Gln 
145                 150                 155                 160 


Val Asp Gln Leu Thr Asn Asp Lys Ala Arg Val Glu Val Glu Arg Asp 
                165                 170                 175     


Asn Leu Ala Glu Asp Ile Met Arg Leu Arg Glu Lys Leu Gln Glu Glu 
            180                 185                 190         


Met Leu Gln Arg Glu Glu Ala Glu Asn Thr Leu Gln Ser Phe Arg Gln 
        195                 200                 205             


Asp Val Asp Asn Ala Ser Leu Ala Arg Leu Asp Leu Glu Arg Lys Val 
    210                 215                 220                 


Glu Ser Leu Gln Glu Glu Ile Ala Phe Leu Lys Lys Leu His Glu Glu 
225                 230                 235                 240 


Glu Ile Gln Glu Leu Gln Ala Gln Ile Gln Glu Gln His Val Gln Ile 
                245                 250                 255     


Asp Val Asp Val Ser Lys Pro Asp Leu Thr Ala Ala Leu Arg Asp Val 
            260                 265                 270         


Arg Gln Gln Tyr Glu Ser Val Ala Ala Lys Asn Leu Gln Glu Ala Glu 
        275                 280                 285             


Glu Trp Tyr Lys Ser Lys Phe Ala Asp Leu Ser Glu Ala Ala Asn Arg 
    290                 295                 300                 


Asn Asn Asp Ala Leu Arg Gln Ala Lys Gln Glu Ser Thr Glu Tyr Arg 
305                 310                 315                 320 


Arg Gln Val Gln Ser Leu Thr Cys Glu Val Asp Ala Leu Lys Gly Thr 
                325                 330                 335     


Asn Glu Ser Leu Glu Arg Gln Met Arg Glu Met Glu Glu Asn Phe Ala 
            340                 345                 350         


Val Glu Ala Ala Asn Tyr Gln Asp Thr Ile Gly Arg Leu Gln Asp Glu 
        355                 360                 365             


Ile Gln Asn Met Lys Glu Glu Met Ala Arg His Leu Arg Glu Tyr Gln 
    370                 375                 380                 


Asp Leu Leu Asn Val Lys Met Ala Leu Asp Ile Glu Ile Ala Thr Tyr 
385                 390                 395                 400 


Arg Lys Leu Leu Glu Gly Glu Glu Ser Arg Ile Ser Leu Pro Leu Pro 
                405                 410                 415     


Asn Phe Ser Ser Leu Asn Leu Arg Glu Thr Asn Leu Asp Ser Leu Pro 
            420                 425                 430         


Leu Val Asp Thr His Ser Lys Arg Thr Leu Leu Ile Lys Thr Val Glu 
        435                 440                 445             


Thr Arg Asp Gly Gln Val Ile Asn Glu Thr Ser Gln His His Asp Asp 
    450                 455                 460                 


Leu Glu 
465     


<210>  1080
<211>  732
<212>  PRT
<213>  Human

<400>  1080

Met Val Arg Ser Gly Asn Lys Ala Ala Val Val Leu Cys Met Asp Val 
1               5                   10                  15      


Gly Phe Thr Met Ser Asn Ser Ile Pro Gly Ile Glu Ser Pro Phe Glu 
            20                  25                  30          


Gln Ala Lys Lys Val Ile Thr Met Phe Val Gln Arg Gln Val Phe Ala 
        35                  40                  45              


Glu Asn Lys Asp Glu Ile Ala Leu Val Leu Phe Gly Thr Asp Gly Thr 
    50                  55                  60                  


Asp Asn Pro Leu Ser Gly Gly Asp Gln Tyr Gln Asn Ile Thr Val His 
65                  70                  75                  80  


Arg His Leu Met Leu Pro Asp Phe Asp Leu Leu Glu Asp Ile Glu Ser 
                85                  90                  95      


Lys Ile Gln Pro Gly Ser Gln Gln Ala Asp Phe Leu Asp Ala Leu Ile 
            100                 105                 110         


Val Ser Met Asp Val Ile Gln His Glu Thr Ile Gly Lys Lys Phe Glu 
        115                 120                 125             


Lys Arg His Ile Glu Ile Phe Thr Asp Leu Ser Ser Arg Phe Ser Lys 
    130                 135                 140                 


Ser Gln Leu Asp Ile Ile Ile His Ser Leu Lys Lys Cys Asp Ile Ser 
145                 150                 155                 160 


Leu Gln Phe Phe Leu Pro Phe Ser Leu Gly Lys Glu Asp Gly Ser Gly 
                165                 170                 175     


Asp Arg Gly Asp Gly Pro Phe Arg Leu Gly Gly His Gly Pro Ser Phe 
            180                 185                 190         


Pro Leu Lys Gly Ile Thr Glu Gln Gln Lys Glu Gly Leu Glu Ile Val 
        195                 200                 205             


Lys Met Val Met Ile Ser Leu Glu Gly Glu Asp Gly Leu Asp Glu Ile 
    210                 215                 220                 


Tyr Ser Phe Ser Glu Ser Leu Arg Lys Leu Cys Val Phe Lys Lys Ile 
225                 230                 235                 240 


Glu Arg His Ser Ile His Trp Pro Cys Arg Leu Thr Ile Gly Ser Asn 
                245                 250                 255     


Leu Ser Ile Arg Ile Ala Ala Tyr Lys Ser Ile Leu Gln Glu Arg Val 
            260                 265                 270         


Lys Lys Thr Trp Thr Val Val Asp Ala Lys Thr Leu Lys Lys Glu Asp 
        275                 280                 285             


Ile Gln Lys Glu Thr Val Tyr Cys Leu Asn Asp Asp Asp Glu Thr Glu 
    290                 295                 300                 


Val Leu Lys Glu Asp Ile Ile Gln Gly Phe Arg Tyr Gly Ser Asp Ile 
305                 310                 315                 320 


Val Pro Phe Ser Lys Val Asp Glu Glu Gln Met Lys Tyr Lys Ser Glu 
                325                 330                 335     


Gly Lys Cys Phe Ser Val Leu Gly Phe Cys Lys Ser Ser Gln Val Gln 
            340                 345                 350         


Arg Arg Phe Phe Met Gly Asn Gln Val Leu Lys Val Phe Ala Ala Arg 
        355                 360                 365             


Asp Asp Glu Ala Ala Ala Val Ala Leu Ser Ser Leu Ile His Ala Leu 
    370                 375                 380                 


Asp Asp Leu Asp Met Val Ala Ile Val Arg Tyr Ala Tyr Asp Lys Arg 
385                 390                 395                 400 


Ala Asn Pro Gln Val Gly Val Ala Phe Pro His Ile Lys His Asn Tyr 
                405                 410                 415     


Glu Cys Leu Val Tyr Val Gln Leu Pro Phe Met Glu Asp Leu Arg Gln 
            420                 425                 430         


Tyr Met Phe Ser Ser Leu Lys Asn Ser Lys Lys Tyr Ala Pro Thr Glu 
        435                 440                 445             


Ala Gln Leu Asn Ala Val Asp Ala Leu Ile Asp Ser Met Ser Leu Ala 
    450                 455                 460                 


Lys Lys Asp Glu Lys Thr Asp Thr Leu Glu Asp Leu Phe Pro Thr Thr 
465                 470                 475                 480 


Lys Ile Pro Asn Pro Arg Phe Gln Arg Leu Phe Gln Cys Leu Leu His 
                485                 490                 495     


Arg Ala Leu His Pro Arg Glu Pro Leu Pro Pro Ile Gln Gln His Ile 
            500                 505                 510         


Trp Asn Met Leu Asn Pro Pro Ala Glu Val Thr Thr Lys Ser Gln Ile 
        515                 520                 525             


Pro Leu Ser Lys Ile Lys Thr Leu Phe Pro Leu Ile Glu Ala Lys Lys 
    530                 535                 540                 


Lys Asp Gln Val Thr Ala Gln Glu Ile Phe Gln Asp Asn His Glu Asp 
545                 550                 555                 560 


Gly Pro Thr Ala Lys Lys Leu Lys Thr Glu Gln Gly Gly Ala His Phe 
                565                 570                 575     


Ser Val Ser Ser Leu Ala Glu Gly Ser Val Thr Ser Val Gly Ser Val 
            580                 585                 590         


Asn Pro Ala Glu Asn Phe Arg Val Leu Val Lys Gln Lys Lys Ala Ser 
        595                 600                 605             


Phe Glu Glu Ala Ser Asn Gln Leu Ile Asn His Ile Glu Gln Phe Leu 
    610                 615                 620                 


Asp Thr Asn Glu Thr Pro Tyr Phe Met Lys Ser Ile Asp Cys Ile Arg 
625                 630                 635                 640 


Ala Phe Arg Glu Glu Ala Ile Lys Phe Ser Glu Glu Gln Arg Phe Asn 
                645                 650                 655     


Asn Phe Leu Lys Ala Leu Gln Glu Lys Val Glu Ile Lys Gln Leu Asn 
            660                 665                 670         


His Phe Trp Glu Ile Val Val Gln Asp Gly Ile Thr Leu Ile Thr Lys 
        675                 680                 685             


Glu Glu Ala Ser Gly Ser Ser Val Thr Ala Glu Glu Ala Lys Lys Phe 
    690                 695                 700                 


Leu Ala Pro Lys Asp Lys Pro Ser Gly Asp Thr Ala Ala Val Phe Glu 
705                 710                 715                 720 


Glu Gly Gly Asp Val Asp Asp Leu Leu Asp Met Ile 
                725                 730         


<210>  1081
<211>  1048
<212>  PRT
<213>  Human

<400>  1081

Met Gln Ser Lys Val Thr Gly Asn Met Pro Thr Gln Ser Leu Leu Met 
1               5                   10                  15      


Tyr Met Asp Gly Pro Glu Val Ile Gly Ser Ser Leu Gly Ser Pro Met 
            20                  25                  30          


Glu Met Glu Asp Ala Leu Ser Met Lys Gly Thr Ala Val Val Pro Phe 
        35                  40                  45              


Arg Ala Thr Gln Glu Lys Asn Val Ile Gln Ile Glu Gly Tyr Met Pro 
    50                  55                  60                  


Leu Asp Cys Met Phe Cys Ser Gln Thr Phe Thr His Ser Glu Asp Leu 
65                  70                  75                  80  


Asn Lys His Val Leu Met Gln His Arg Pro Thr Leu Cys Glu Pro Ala 
                85                  90                  95      


Val Leu Arg Val Glu Ala Glu Tyr Leu Ser Pro Leu Asp Lys Ser Gln 
            100                 105                 110         


Val Arg Thr Glu Pro Pro Lys Glu Lys Asn Cys Lys Glu Asn Glu Phe 
        115                 120                 125             


Ser Cys Glu Val Cys Gly Gln Thr Phe Arg Val Ala Phe Asp Val Glu 
    130                 135                 140                 


Ile His Met Arg Thr His Lys Asp Ser Phe Thr Tyr Gly Cys Asn Met 
145                 150                 155                 160 


Cys Gly Arg Arg Phe Lys Glu Pro Trp Phe Leu Lys Asn His Met Arg 
                165                 170                 175     


Thr His Asn Gly Lys Ser Gly Ala Arg Ser Lys Leu Gln Gln Gly Leu 
            180                 185                 190         


Glu Ser Ser Pro Ala Thr Ile Asn Glu Val Val Gln Val His Ala Ala 
        195                 200                 205             


Glu Ser Ile Ser Ser Pro Tyr Lys Ile Cys Met Val Cys Gly Phe Leu 
    210                 215                 220                 


Phe Pro Asn Lys Glu Ser Leu Ile Glu His Arg Lys Val His Thr Lys 
225                 230                 235                 240 


Lys Thr Ala Phe Gly Thr Ser Ser Ala Gln Thr Asp Ser Pro Gln Gly 
                245                 250                 255     


Gly Met Pro Ser Ser Arg Glu Asp Phe Leu Gln Leu Phe Asn Leu Arg 
            260                 265                 270         


Pro Lys Ser His Pro Glu Thr Gly Lys Lys Pro Val Arg Cys Ile Pro 
        275                 280                 285             


Gln Leu Asp Pro Phe Thr Thr Phe Gln Ala Trp Gln Leu Ala Thr Lys 
    290                 295                 300                 


Gly Lys Val Ala Ile Cys Gln Glu Val Lys Glu Ser Gly Gln Glu Gly 
305                 310                 315                 320 


Ser Thr Asp Asn Asp Asp Ser Ser Ser Glu Lys Glu Leu Gly Glu Thr 
                325                 330                 335     


Asn Lys Gly Ser Cys Ala Gly Leu Ser Gln Glu Lys Glu Lys Cys Lys 
            340                 345                 350         


His Ser His Gly Glu Ala Pro Ser Val Asp Ala Asp Pro Lys Leu Pro 
        355                 360                 365             


Ser Ser Lys Glu Lys Pro Thr His Cys Ser Glu Cys Gly Lys Ala Phe 
    370                 375                 380                 


Arg Thr Tyr His Gln Leu Val Leu His Ser Arg Val His Lys Lys Asp 
385                 390                 395                 400 


Arg Arg Ala Gly Ala Glu Ser Pro Thr Met Ser Val Asp Gly Arg Gln 
                405                 410                 415     


Pro Gly Thr Cys Ser Pro Asp Leu Ala Ala Pro Leu Asp Glu Asn Gly 
            420                 425                 430         


Ala Val Asp Arg Gly Glu Gly Gly Ser Glu Asp Gly Ser Glu Asp Gly 
        435                 440                 445             


Leu Pro Glu Gly Ile His Leu Asp Lys Asn Asp Asp Gly Gly Lys Ile 
    450                 455                 460                 


Lys His Leu Thr Ser Ser Arg Glu Cys Ser Tyr Cys Gly Lys Phe Phe 
465                 470                 475                 480 


Arg Ser Asn Tyr Tyr Leu Asn Ile His Leu Arg Thr His Thr Gly Glu 
                485                 490                 495     


Lys Pro Tyr Lys Cys Glu Phe Cys Glu Tyr Ala Ala Ala Gln Lys Thr 
            500                 505                 510         


Ser Leu Arg Tyr His Leu Glu Arg His His Lys Glu Lys Gln Thr Asp 
        515                 520                 525             


Val Ala Ala Glu Val Lys Asn Asp Gly Lys Asn Gln Asp Thr Glu Asp 
    530                 535                 540                 


Ala Leu Leu Thr Ala Asp Ser Ala Gln Thr Lys Asn Leu Lys Arg Phe 
545                 550                 555                 560 


Phe Asp Gly Ala Lys Asp Val Thr Gly Ser Pro Pro Ala Lys Gln Leu 
                565                 570                 575     


Lys Glu Met Pro Ser Val Phe Gln Asn Val Leu Gly Ser Ala Val Leu 
            580                 585                 590         


Ser Pro Ala His Lys Asp Thr Gln Asp Phe His Lys Asn Ala Ala Asp 
        595                 600                 605             


Asp Ser Ala Asp Lys Val Asn Lys Asn Pro Thr Pro Ala Tyr Leu Asp 
    610                 615                 620                 


Leu Leu Lys Lys Arg Ser Ala Val Glu Thr Gln Ala Asn Asn Leu Ile 
625                 630                 635                 640 


Cys Arg Thr Lys Ala Asp Val Thr Pro Pro Pro Asp Gly Ser Thr Thr 
                645                 650                 655     


His Asn Leu Glu Val Ser Pro Lys Glu Lys Gln Thr Glu Thr Ala Ala 
            660                 665                 670         


Asp Cys Arg Tyr Arg Pro Ser Val Asp Cys His Glu Lys Pro Leu Asn 
        675                 680                 685             


Leu Ser Val Gly Ala Leu His Asn Cys Pro Ala Ile Ser Leu Ser Lys 
    690                 695                 700                 


Ser Leu Ile Pro Ser Ile Thr Cys Pro Phe Cys Thr Phe Lys Thr Phe 
705                 710                 715                 720 


Tyr Pro Glu Val Leu Met Met His Gln Arg Leu Glu His Lys Tyr Asn 
                725                 730                 735     


Pro Asp Val His Lys Asn Cys Arg Asn Lys Ser Leu Leu Arg Ser Arg 
            740                 745                 750         


Arg Thr Gly Cys Pro Pro Ala Leu Leu Gly Lys Asp Val Pro Pro Leu 
        755                 760                 765             


Ser Ser Phe Cys Lys Pro Lys Pro Lys Ser Ala Phe Pro Ala Gln Ser 
    770                 775                 780                 


Lys Ser Leu Pro Ser Ala Lys Gly Lys Gln Ser Pro Pro Gly Pro Gly 
785                 790                 795                 800 


Lys Ala Pro Leu Thr Ser Gly Ile Asp Ser Ser Thr Leu Ala Pro Ser 
                805                 810                 815     


Asn Leu Lys Ser His Arg Pro Gln Gln Asn Val Gly Val Gln Gly Ala 
            820                 825                 830         


Ala Thr Arg Gln Gln Gln Ser Glu Met Phe Pro Lys Thr Ser Val Ser 
        835                 840                 845             


Pro Ala Pro Asp Lys Thr Lys Arg Pro Glu Thr Lys Leu Lys Pro Leu 
    850                 855                 860                 


Pro Val Ala Pro Ser Gln Pro Thr Leu Gly Ser Ser Asn Ile Asn Gly 
865                 870                 875                 880 


Ser Ile Asp Tyr Pro Ala Lys Asn Asp Ser Pro Trp Ala Pro Pro Gly 
                885                 890                 895     


Arg Asp Tyr Phe Cys Asn Arg Ser Ala Ser Asn Thr Ala Ala Glu Phe 
            900                 905                 910         


Gly Glu Pro Leu Pro Lys Arg Leu Lys Ser Ser Val Val Ala Leu Asp 
        915                 920                 925             


Val Asp Gln Pro Gly Ala Asn Tyr Arg Arg Gly Tyr Asp Leu Pro Lys 
    930                 935                 940                 


Tyr His Met Val Arg Gly Ile Thr Ser Leu Leu Pro Gln Asp Cys Val 
945                 950                 955                 960 


Tyr Pro Ser Gln Ala Leu Pro Pro Lys Pro Arg Phe Leu Ser Ser Ser 
                965                 970                 975     


Glu Val Asp Ser Pro Asn Val Leu Thr Val Gln Lys Pro Tyr Gly Gly 
            980                 985                 990         


Ser Gly Pro Leu Tyr Thr Cys Val  Pro Ala Gly Ser Pro  Ala Ser Ser 
        995                 1000                 1005             


Ser Thr  Leu Glu Gly Lys Arg  Pro Val Ser Tyr Gln  His Leu Ser 
    1010                 1015                 1020             


Asn Ser  Met Ala Gln Lys Arg  Asn Tyr Glu Asn Phe  Ile Gly Asn 
    1025                 1030                 1035             


Ala His  Tyr Arg Pro Asn Asp  Lys Lys Thr 
    1040                 1045             


<210>  1082
<211>  896
<212>  PRT
<213>  Human

<400>  1082

Met Thr Glu Glu Ser Glu Glu Thr Val Leu Tyr Ile Glu His Arg Tyr 
1               5                   10                  15      


Val Cys Ser Glu Cys Asn Gln Leu Tyr Gly Ser Leu Glu Glu Val Leu 
            20                  25                  30          


Met His Gln Asn Ser His Val Pro Gln Gln His Phe Glu Leu Val Gly 
        35                  40                  45              


Val Ala Asp Pro Gly Val Thr Val Ala Thr Asp Thr Ala Ser Gly Thr 
    50                  55                  60                  


Gly Leu Tyr Gln Thr Leu Val Gln Glu Ser Gln Tyr Gln Cys Leu Glu 
65                  70                  75                  80  


Cys Gly Gln Leu Leu Met Ser Pro Ser Gln Leu Leu Glu His Gln Glu 
                85                  90                  95      


Leu His Leu Lys Met Met Ala Pro Gln Glu Ala Val Pro Ala Glu Pro 
            100                 105                 110         


Ser Pro Lys Ala Pro Pro Leu Ser Ser Ser Thr Ile His Tyr Glu Cys 
        115                 120                 125             


Val Asp Cys Lys Ala Leu Phe Ala Ser Gln Glu Leu Trp Leu Asn His 
    130                 135                 140                 


Arg Gln Thr His Leu Arg Ala Thr Pro Thr Lys Ala Pro Ala Pro Val 
145                 150                 155                 160 


Val Leu Gly Ser Pro Val Val Leu Gly Pro Pro Val Gly Gln Ala Arg 
                165                 170                 175     


Val Ala Val Glu His Ser Tyr Arg Lys Ala Glu Glu Gly Gly Glu Gly 
            180                 185                 190         


Ala Thr Val Pro Ser Ala Ala Ala Thr Thr Thr Glu Val Val Thr Glu 
        195                 200                 205             


Val Glu Leu Leu Leu Tyr Lys Cys Ser Glu Cys Ser Gln Leu Phe Gln 
    210                 215                 220                 


Leu Pro Ala Asp Phe Leu Glu His Gln Ala Thr His Phe Pro Ala Pro 
225                 230                 235                 240 


Val Pro Glu Ser Gln Glu Pro Ala Leu Gln Gln Glu Val Gln Ala Ser 
                245                 250                 255     


Ser Pro Ala Glu Val Pro Val Ser Gln Pro Asp Pro Leu Pro Ala Ser 
            260                 265                 270         


Asp His Ser Tyr Glu Leu Arg Asn Gly Glu Ala Ile Gly Arg Asp Arg 
        275                 280                 285             


Arg Gly Arg Arg Ala Arg Arg Asn Asn Ser Gly Glu Ala Gly Gly Ala 
    290                 295                 300                 


Ala Thr Gln Glu Leu Phe Cys Ser Ala Cys Asp Gln Leu Phe Leu Ser 
305                 310                 315                 320 


Pro His Gln Leu Gln Gln His Leu Arg Ser His Arg Glu Gly Val Phe 
                325                 330                 335     


Lys Cys Pro Leu Cys Ser Arg Val Phe Pro Ser Pro Ser Ser Leu Asp 
            340                 345                 350         


Gln His Leu Gly Asp His Ser Ser Glu Ser His Phe Leu Cys Val Asp 
        355                 360                 365             


Cys Gly Leu Ala Phe Gly Thr Glu Ala Leu Leu Leu Ala His Arg Arg 
    370                 375                 380                 


Ala His Thr Pro Asn Pro Leu His Ser Cys Pro Cys Gly Lys Thr Phe 
385                 390                 395                 400 


Val Asn Leu Thr Lys Phe Leu Tyr His Arg Arg Thr His Gly Val Gly 
                405                 410                 415     


Gly Val Pro Leu Pro Thr Thr Pro Val Pro Pro Glu Glu Pro Val Ile 
            420                 425                 430         


Gly Phe Pro Glu Pro Ala Pro Ala Glu Thr Gly Glu Pro Glu Ala Pro 
        435                 440                 445             


Glu Pro Pro Val Ser Glu Glu Thr Ser Ala Gly Pro Ala Ala Pro Gly 
    450                 455                 460                 


Thr Tyr Arg Cys Leu Leu Cys Ser Arg Glu Phe Gly Lys Ala Leu Gln 
465                 470                 475                 480 


Leu Thr Arg His Gln Arg Phe Val His Arg Leu Glu Arg Arg His Lys 
                485                 490                 495     


Cys Ser Ile Cys Gly Lys Met Phe Lys Lys Lys Ser His Val Arg Asn 
            500                 505                 510         


His Leu Arg Thr His Thr Gly Glu Arg Pro Phe Pro Cys Pro Asp Cys 
        515                 520                 525             


Ser Lys Pro Phe Asn Ser Pro Ala Asn Leu Ala Arg His Arg Leu Thr 
    530                 535                 540                 


His Thr Gly Glu Arg Pro Tyr Arg Cys Gly Asp Cys Gly Lys Ala Phe 
545                 550                 555                 560 


Thr Gln Ser Ser Thr Leu Arg Gln His Arg Leu Val His Ala Gln His 
                565                 570                 575     


Phe Pro Tyr Arg Cys Gln Glu Cys Gly Val Arg Phe His Arg Pro Tyr 
            580                 585                 590         


Arg Leu Leu Met His Arg Tyr His His Thr Gly Glu Tyr Pro Tyr Lys 
        595                 600                 605             


Cys Arg Glu Cys Pro Arg Ser Phe Leu Leu Arg Arg Leu Leu Glu Val 
    610                 615                 620                 


His Gln Leu Val Val His Ala Gly Arg Gln Pro His Arg Cys Pro Ser 
625                 630                 635                 640 


Cys Gly Ala Ala Phe Pro Ser Ser Leu Arg Leu Arg Glu His Arg Cys 
                645                 650                 655     


Ala Ala Ala Ala Ala Gln Ala Pro Arg Arg Phe Glu Cys Gly Thr Cys 
            660                 665                 670         


Gly Lys Lys Val Gly Ser Ala Ala Arg Leu Gln Ala His Glu Ala Ala 
        675                 680                 685             


His Ala Ala Ala Gly Pro Gly Glu Val Leu Ala Lys Glu Pro Pro Ala 
    690                 695                 700                 


Pro Arg Ala Pro Arg Ala Thr Arg Ala Pro Val Ala Ser Pro Ala Ala 
705                 710                 715                 720 


Leu Gly Ser Thr Ala Thr Ala Ser Pro Ala Ala Pro Ala Arg Arg Arg 
                725                 730                 735     


Gly Leu Glu Cys Ser Glu Cys Lys Lys Leu Phe Ser Thr Glu Thr Ser 
            740                 745                 750         


Leu Gln Val His Arg Arg Ile His Thr Gly Glu Arg Pro Tyr Pro Cys 
        755                 760                 765             


Pro Asp Cys Gly Lys Ala Phe Arg Gln Ser Thr His Leu Lys Asp His 
    770                 775                 780                 


Arg Arg Leu His Thr Gly Glu Arg Pro Phe Ala Cys Glu Val Cys Gly 
785                 790                 795                 800 


Lys Ala Phe Ala Ile Ser Met Arg Leu Ala Glu His Arg Arg Ile His 
                805                 810                 815     


Thr Gly Glu Arg Pro Tyr Ser Cys Pro Asp Cys Gly Lys Ser Tyr Arg 
            820                 825                 830         


Ser Phe Ser Asn Leu Trp Lys His Arg Lys Thr His Gln Gln Gln His 
        835                 840                 845             


Gln Ala Ala Val Arg Gln Gln Leu Ala Glu Ala Glu Ala Ala Val Gly 
    850                 855                 860                 


Leu Ala Val Met Glu Thr Ala Val Glu Ala Leu Pro Leu Val Glu Ala 
865                 870                 875                 880 


Ile Glu Ile Tyr Pro Leu Ala Glu Ala Glu Gly Val Gln Ile Ser Gly 
                885                 890                 895     


<210>  1083
<211>  1001
<212>  PRT
<213>  Human

<400>  1083

Met Lys Arg Ile Phe Ser Cys Ser Ser Thr Gln Val Ala Val Glu Arg 
1               5                   10                  15      


Trp Asn Arg His Asp Gln Lys Leu Leu Glu Ala Val His Arg Gly Asp 
            20                  25                  30          


Val Gly Arg Val Ala Ala Leu Ala Ser Arg Lys Ser Ala Arg Pro Thr 
        35                  40                  45              


Lys Leu Asp Ser Asn Gly Gln Ser Pro Phe His Leu Ala Ala Ser Lys 
    50                  55                  60                  


Gly Leu Thr Glu Cys Leu Thr Ile Leu Leu Ala Asn Gly Ala Asp Ile 
65                  70                  75                  80  


Asn Ser Lys Asn Glu Asp Gly Ser Thr Ala Leu His Leu Ala Thr Ile 
                85                  90                  95      


Ser Cys Gln Pro Gln Cys Val Lys Val Leu Leu Gln His Gly Ala Asn 
            100                 105                 110         


Glu Asp Ala Val Asp Ala Glu Asn Arg Ser Pro Leu His Trp Ala Ala 
        115                 120                 125             


Ser Ser Gly Cys Ala Ser Ser Val Leu Leu Leu Cys Asp His Glu Ala 
    130                 135                 140                 


Phe Leu Asp Val Leu Asp Asn Asp Gly Arg Thr Pro Leu Met Ile Ala 
145                 150                 155                 160 


Ser Leu Gly Gly His Ala Ala Ile Cys Ser Gln Leu Leu Gln Arg Gly 
                165                 170                 175     


Ala Arg Val Asn Val Thr Asp Lys Asn Asp Lys Ser Ala Leu Ile Leu 
            180                 185                 190         


Ala Cys Glu Lys Gly Ser Ala Glu Val Ala Glu Leu Leu Leu Ser His 
        195                 200                 205             


Gly Ala Asp Ala Gly Ala Val Asp Ser Thr Gly His Asp Ala Leu His 
    210                 215                 220                 


Tyr Ala Leu His Thr Gln Asp Lys Ala Leu Trp Arg His Leu Gln Gln 
225                 230                 235                 240 


Ala Leu Ser Arg Arg Arg Arg Gly Gly Gln Arg Leu Val Gln His Pro 
                245                 250                 255     


Asp Leu Ala Ser Gln Ala Ser Pro Ser Glu Pro Gln Ala Gly Ser Pro 
            260                 265                 270         


Pro Lys Ser Ser Trp Arg Ala Glu Pro Glu Glu Glu Gln Glu Glu Lys 
        275                 280                 285             


Glu Asp Glu Asp Pro Cys Ser Glu Glu Trp Arg Trp Lys Tyr Glu Glu 
    290                 295                 300                 


Glu Arg Arg Lys Val Val Arg Leu Glu Gln Glu Leu Val Gln Lys Thr 
305                 310                 315                 320 


Glu Glu Cys Lys Thr Gln Ala Ala Ala Tyr Leu Asp Leu Glu Asn Gln 
                325                 330                 335     


Ile Arg Glu Gln Ala Gln Glu Leu Gly Val Leu Leu Ser Trp Glu Pro 
            340                 345                 350         


Arg Ala Ser Gly Lys Gln Gly Ser Ser Leu Arg Pro Gly Gly Asp Gly 
        355                 360                 365             


Met Glu Gln Gly Cys Pro Lys Asp Leu Leu Ala Glu Ser Thr Gln Glu 
    370                 375                 380                 


Leu Lys Lys Gln Gln Gln Ala Ala Ala Thr Val Asn Pro Val Leu Ala 
385                 390                 395                 400 


Pro Lys Lys Ala Glu Asp Ser Ala Pro Gly Lys Ile Gln Tyr Glu Val 
                405                 410                 415     


His Gly Arg Ser Gln Pro Glu Glu Gln Gly Pro Pro Gln Ser Pro Ala 
            420                 425                 430         


Ser Glu Thr Ile Arg Lys Ala Thr Gly Gln Gln Leu Thr Thr Asn Gly 
        435                 440                 445             


Ala Gln Thr Phe Gly Pro Asp His Ala Asp Gln Leu Pro Ala Gly Gln 
    450                 455                 460                 


Lys Glu Ser Ser Gln Val Leu Gly Val Glu Pro Gly Gly Thr Val Ala 
465                 470                 475                 480 


Glu Pro Val Gly Pro Ala Ala Met Asn Gln Leu Leu Leu Gln Leu Arg 
                485                 490                 495     


Glu Glu Leu Ala Ala Val Trp Arg Glu Lys Asp Ala Ala Arg Gly Ala 
            500                 505                 510         


Leu Ser Arg Pro Val Met Glu Gly Ala Leu Gly Thr Pro Arg Ala Glu 
        515                 520                 525             


Ala Ala Ala Ala Ala Trp Glu Lys Met Glu Ala Arg Leu Glu Arg Val 
    530                 535                 540                 


Leu Ala Arg Leu Glu Trp Ala Lys Ala Gly Leu Gln Val Lys Pro Glu 
545                 550                 555                 560 


Val Pro Ser Gln Glu Ser Arg Glu Gly Ala Leu Lys Ala Ala Pro Gly 
                565                 570                 575     


Ser Ile Lys Gln Asp Glu Glu Lys Glu Lys Arg Val Pro Gly Ala Arg 
            580                 585                 590         


Gly Glu Pro Leu Gly Ala Leu Gly Gly Glu Lys Ala Leu Gly Gly Leu 
        595                 600                 605             


Ala Lys Gly Gln Leu Glu Lys Glu Met Ser Val Leu Arg Leu Ser Asn 
    610                 615                 620                 


Ser Asn Leu Leu Glu Glu Leu Gly Glu Leu Gly Arg Glu Arg Gln Arg 
625                 630                 635                 640 


Leu Gln Arg Glu Leu Gln Ser Leu Ser Gln Arg Leu Gln Arg Glu Phe 
                645                 650                 655     


Val Pro Lys Pro Glu Ala Gln Val Gln Leu Gln Gln Leu Arg Gln Ser 
            660                 665                 670         


Val Gly Leu Leu Thr Asn Glu Leu Ala Met Glu Lys Glu Ala Thr Glu 
        675                 680                 685             


Lys Leu Arg Lys Leu Leu Ala Ser Gln Ser Ser Gly Leu Arg Gly Leu 
    690                 695                 700                 


Trp Asp Cys Leu Pro Ala Asp Leu Val Gly Glu Arg Ser Ala Gln Ser 
705                 710                 715                 720 


Lys Ala Ala Glu Ser Leu Glu Glu Leu Arg Ala Cys Ile Ser Thr Leu 
                725                 730                 735     


Val Asp Arg His Arg Glu Ala Gln Gln Val Leu Ala Arg Leu Gln Glu 
            740                 745                 750         


Glu Asn Gln Gln Leu Arg Gly Ser Leu Ser Pro Cys Arg Glu Pro Gly 
        755                 760                 765             


Thr Ser Leu Lys Ala Pro Ala Ser Pro Gln Val Ala Ala Leu Glu Gln 
    770                 775                 780                 


Asp Leu Gly Lys Leu Glu Glu Glu Leu Arg Ala Val Gln Ala Thr Met 
785                 790                 795                 800 


Ser Gly Lys Ser Gln Glu Ile Gly Lys Leu Lys Gln Leu Leu Tyr Gln 
                805                 810                 815     


Ala Thr Glu Glu Val Ala Glu Leu Arg Ala Arg Glu Ala Ala Ser Leu 
            820                 825                 830         


Arg Gln His Glu Lys Thr Arg Gly Ser Leu Val Ala Gln Ala Gln Ala 
        835                 840                 845             


Trp Gly Gln Glu Leu Lys Ala Leu Leu Glu Lys Tyr Asn Thr Ala Cys 
    850                 855                 860                 


Arg Glu Val Gly Arg Leu Arg Glu Ala Val Ala Glu Glu Arg Arg Arg 
865                 870                 875                 880 


Ser Gly Asp Leu Ala Ala Gln Ala Ala Glu Gln Glu Arg Gln Ala Ser 
                885                 890                 895     


Glu Met Arg Gly Arg Ser Glu Gln Phe Glu Lys Thr Ala Glu Leu Leu 
            900                 905                 910         


Lys Glu Lys Met Glu His Leu Ile Gly Ala Cys Arg Asp Lys Glu Ala 
        915                 920                 925             


Lys Ile Lys Glu Leu Leu Lys Lys Leu Glu Gln Leu Ser Glu Glu Val 
    930                 935                 940                 


Leu Ala Ile Arg Gly Glu Asn Ala Arg Leu Ala Leu Gln Leu Gln Asp 
945                 950                 955                 960 


Ser Gln Lys Asn His Glu Glu Ile Ile Ser Thr Tyr Arg Asn His Leu 
                965                 970                 975     


Leu Asn Ala Ala Arg Gly Tyr Met Glu His Glu Val Tyr Asn Ile Leu 
            980                 985                 990         


Leu Gln Ile Leu Ser Met Glu Glu  Glu 
        995                 1000     


<210>  1084
<211>  229
<212>  PRT
<213>  Human

<400>  1084

Met Asn Ile Arg Asn Ala Gln Pro Asp Asp Leu Met Asn Met Gln His 
1               5                   10                  15      


Cys Asn Leu Leu Cys Leu Pro Glu Asn Tyr Gln Met Lys Tyr Tyr Leu 
            20                  25                  30          


Tyr His Gly Leu Ser Trp Pro Gln Leu Ser Tyr Ile Ala Glu Asp Glu 
        35                  40                  45              


Asp Gly Lys Ile Val Gly Tyr Val Leu Ala Lys Met Glu Glu Glu Pro 
    50                  55                  60                  


Asp Asp Val Pro His Gly His Ile Thr Ser Leu Ala Val Lys Arg Ser 
65                  70                  75                  80  


His Arg Arg Leu Gly Leu Ala Gln Lys Leu Met Asp Gln Ala Ser Arg 
                85                  90                  95      


Ala Met Ile Glu Asn Phe Asn Ala Lys Tyr Val Ser Leu His Val Arg 
            100                 105                 110         


Lys Ser Asn Arg Pro Ala Leu His Leu Tyr Ser Asn Thr Leu Asn Phe 
        115                 120                 125             


Gln Ile Ser Glu Val Glu Pro Lys Tyr Tyr Ala Asp Gly Glu Asp Ala 
    130                 135                 140                 


Tyr Ala Met Lys Arg Asp Leu Ser Gln Met Ala Asp Glu Leu Arg Arg 
145                 150                 155                 160 


Gln Met Asp Leu Lys Lys Gly Gly Tyr Val Val Leu Gly Ser Arg Glu 
                165                 170                 175     


Asn Gln Glu Thr Gln Gly Ser Thr Leu Ser Asp Ser Glu Glu Ala Cys 
            180                 185                 190         


Gln Gln Lys Asn Pro Ala Thr Glu Glu Ser Gly Ser Asp Ser Lys Glu 
        195                 200                 205             


Pro Lys Glu Ser Val Glu Ser Thr Asn Val Gln Asp Ser Ser Glu Ser 
    210                 215                 220                 


Ser Asp Ser Thr Ser 
225                 


<210>  1085
<211>  1863
<212>  PRT
<213>  Human

<400>  1085

Met Asp Leu Ser Ala Leu Arg Val Glu Glu Val Gln Asn Val Ile Asn 
1               5                   10                  15      


Ala Met Gln Lys Ile Leu Glu Cys Pro Ile Cys Leu Glu Leu Ile Lys 
            20                  25                  30          


Glu Pro Val Ser Thr Lys Cys Asp His Ile Phe Cys Lys Phe Cys Met 
        35                  40                  45              


Leu Lys Leu Leu Asn Gln Lys Lys Gly Pro Ser Gln Cys Pro Leu Cys 
    50                  55                  60                  


Lys Asn Asp Ile Thr Lys Arg Ser Leu Gln Glu Ser Thr Arg Phe Ser 
65                  70                  75                  80  


Gln Leu Val Glu Glu Leu Leu Lys Ile Ile Cys Ala Phe Gln Leu Asp 
                85                  90                  95      


Thr Gly Leu Glu Tyr Ala Asn Ser Tyr Asn Phe Ala Lys Lys Glu Asn 
            100                 105                 110         


Asn Ser Pro Glu His Leu Lys Asp Glu Val Ser Ile Ile Gln Ser Met 
        115                 120                 125             


Gly Tyr Arg Asn Arg Ala Lys Arg Leu Leu Gln Ser Glu Pro Glu Asn 
    130                 135                 140                 


Pro Ser Leu Gln Glu Thr Ser Leu Ser Val Gln Leu Ser Asn Leu Gly 
145                 150                 155                 160 


Thr Val Arg Thr Leu Arg Thr Lys Gln Arg Ile Gln Pro Gln Lys Thr 
                165                 170                 175     


Ser Val Tyr Ile Glu Leu Gly Ser Asp Ser Ser Glu Asp Thr Val Asn 
            180                 185                 190         


Lys Ala Thr Tyr Cys Ser Val Gly Asp Gln Glu Leu Leu Gln Ile Thr 
        195                 200                 205             


Pro Gln Gly Thr Arg Asp Glu Ile Ser Leu Asp Ser Ala Lys Lys Ala 
    210                 215                 220                 


Ala Cys Glu Phe Ser Glu Thr Asp Val Thr Asn Thr Glu His His Gln 
225                 230                 235                 240 


Pro Ser Asn Asn Asp Leu Asn Thr Thr Glu Lys Arg Ala Ala Glu Arg 
                245                 250                 255     


His Pro Glu Lys Tyr Gln Gly Ser Ser Val Ser Asn Leu His Val Glu 
            260                 265                 270         


Pro Cys Gly Thr Asn Thr His Ala Ser Ser Leu Gln His Glu Asn Ser 
        275                 280                 285             


Ser Leu Leu Leu Thr Lys Asp Arg Met Asn Val Glu Lys Ala Glu Phe 
    290                 295                 300                 


Cys Asn Lys Ser Lys Gln Pro Gly Leu Ala Arg Ser Gln His Asn Arg 
305                 310                 315                 320 


Trp Ala Gly Ser Lys Glu Thr Cys Asn Asp Arg Arg Thr Pro Ser Thr 
                325                 330                 335     


Glu Lys Lys Val Asp Leu Asn Ala Asp Pro Leu Cys Glu Arg Lys Glu 
            340                 345                 350         


Trp Asn Lys Gln Lys Leu Pro Cys Ser Glu Asn Pro Arg Asp Thr Glu 
        355                 360                 365             


Asp Val Pro Trp Ile Thr Leu Asn Ser Ser Ile Gln Lys Val Asn Glu 
    370                 375                 380                 


Trp Phe Ser Arg Ser Asp Glu Leu Leu Gly Ser Asp Asp Ser His Asp 
385                 390                 395                 400 


Gly Glu Ser Glu Ser Asn Ala Lys Val Ala Asp Val Leu Asp Val Leu 
                405                 410                 415     


Asn Glu Val Asp Glu Tyr Ser Gly Ser Ser Glu Lys Ile Asp Leu Leu 
            420                 425                 430         


Ala Ser Asp Pro His Glu Ala Leu Ile Cys Lys Ser Glu Arg Val His 
        435                 440                 445             


Ser Lys Ser Val Glu Ser Asn Ile Glu Asp Lys Ile Phe Gly Lys Thr 
    450                 455                 460                 


Tyr Arg Lys Lys Ala Ser Leu Pro Asn Leu Ser His Val Thr Glu Asn 
465                 470                 475                 480 


Leu Ile Ile Gly Ala Phe Val Thr Glu Pro Gln Ile Ile Gln Glu Arg 
                485                 490                 495     


Pro Leu Thr Asn Lys Leu Lys Arg Lys Arg Arg Pro Thr Ser Gly Leu 
            500                 505                 510         


His Pro Glu Asp Phe Ile Lys Lys Ala Asp Leu Ala Val Gln Lys Thr 
        515                 520                 525             


Pro Glu Met Ile Asn Gln Gly Thr Asn Gln Thr Glu Gln Asn Gly Gln 
    530                 535                 540                 


Val Met Asn Ile Thr Asn Ser Gly His Glu Asn Lys Thr Lys Gly Asp 
545                 550                 555                 560 


Ser Ile Gln Asn Glu Lys Asn Pro Asn Pro Ile Glu Ser Leu Glu Lys 
                565                 570                 575     


Glu Ser Ala Phe Lys Thr Lys Ala Glu Pro Ile Ser Ser Ser Ile Ser 
            580                 585                 590         


Asn Met Glu Leu Glu Leu Asn Ile His Asn Ser Lys Ala Pro Lys Lys 
        595                 600                 605             


Asn Arg Leu Arg Arg Lys Ser Ser Thr Arg His Ile His Ala Leu Glu 
    610                 615                 620                 


Leu Val Val Ser Arg Asn Leu Ser Pro Pro Asn Cys Thr Glu Leu Gln 
625                 630                 635                 640 


Ile Asp Ser Cys Ser Ser Ser Glu Glu Ile Lys Lys Lys Lys Tyr Asn 
                645                 650                 655     


Gln Met Pro Val Arg His Ser Arg Asn Leu Gln Leu Met Glu Gly Lys 
            660                 665                 670         


Glu Pro Ala Thr Gly Ala Lys Lys Ser Asn Lys Pro Asn Glu Gln Thr 
        675                 680                 685             


Ser Lys Arg His Asp Ser Asp Thr Phe Pro Glu Leu Lys Leu Thr Asn 
    690                 695                 700                 


Ala Pro Gly Ser Phe Thr Lys Cys Ser Asn Thr Ser Glu Leu Lys Glu 
705                 710                 715                 720 


Phe Val Asn Pro Ser Leu Pro Arg Glu Glu Lys Glu Glu Lys Leu Glu 
                725                 730                 735     


Thr Val Lys Val Ser Asn Asn Ala Glu Asp Pro Lys Asp Leu Met Leu 
            740                 745                 750         


Ser Gly Glu Arg Val Leu Gln Thr Glu Arg Ser Val Glu Ser Ser Ser 
        755                 760                 765             


Ile Ser Leu Val Pro Gly Thr Asp Tyr Gly Thr Gln Glu Ser Ile Ser 
    770                 775                 780                 


Leu Leu Glu Val Ser Thr Leu Gly Lys Ala Lys Thr Glu Pro Asn Lys 
785                 790                 795                 800 


Cys Val Ser Gln Cys Ala Ala Phe Glu Asn Pro Lys Gly Leu Ile His 
                805                 810                 815     


Gly Cys Ser Lys Asp Asn Arg Asn Asp Thr Glu Gly Phe Lys Tyr Pro 
            820                 825                 830         


Leu Gly His Glu Val Asn His Ser Arg Glu Thr Ser Ile Glu Met Glu 
        835                 840                 845             


Glu Ser Glu Leu Asp Ala Gln Tyr Leu Gln Asn Thr Phe Lys Val Ser 
    850                 855                 860                 


Lys Arg Gln Ser Phe Ala Pro Phe Ser Asn Pro Gly Asn Ala Glu Glu 
865                 870                 875                 880 


Glu Cys Ala Thr Phe Ser Ala His Ser Gly Ser Leu Lys Lys Gln Ser 
                885                 890                 895     


Pro Lys Val Thr Phe Glu Cys Glu Gln Lys Glu Glu Asn Gln Gly Lys 
            900                 905                 910         


Asn Glu Ser Asn Ile Lys Pro Val Gln Thr Val Asn Ile Thr Ala Gly 
        915                 920                 925             


Phe Pro Val Val Gly Gln Lys Asp Lys Pro Val Asp Asn Ala Lys Cys 
    930                 935                 940                 


Ser Ile Lys Gly Gly Ser Arg Phe Cys Leu Ser Ser Gln Phe Arg Gly 
945                 950                 955                 960 


Asn Glu Thr Gly Leu Ile Thr Pro Asn Lys His Gly Leu Leu Gln Asn 
                965                 970                 975     


Pro Tyr Arg Ile Pro Pro Leu Phe Pro Ile Lys Ser Phe Val Lys Thr 
            980                 985                 990         


Lys Cys Lys Lys Asn Leu Leu Glu  Glu Asn Phe Glu Glu  His Ser Met 
        995                 1000                 1005             


Ser Pro  Glu Arg Glu Met Gly  Asn Glu Asn Ile Pro  Ser Thr Val 
    1010                 1015                 1020             


Ser Thr  Ile Ser Arg Asn Asn  Ile Arg Glu Asn Val  Phe Lys Glu 
    1025                 1030                 1035             


Ala Ser  Ser Ser Asn Ile Asn  Glu Val Gly Ser Ser  Thr Asn Glu 
    1040                 1045                 1050             


Val Gly  Ser Ser Ile Asn Glu  Ile Gly Ser Ser Asp  Glu Asn Ile 
    1055                 1060                 1065             


Gln Ala  Glu Leu Gly Arg Asn  Arg Gly Pro Lys Leu  Asn Ala Met 
    1070                 1075                 1080             


Leu Arg  Leu Gly Val Leu Gln  Pro Glu Val Tyr Lys  Gln Ser Leu 
    1085                 1090                 1095             


Pro Gly  Ser Asn Cys Lys His  Pro Glu Ile Lys Lys  Gln Glu Tyr 
    1100                 1105                 1110             


Glu Glu  Val Val Gln Thr Val  Asn Thr Asp Phe Ser  Pro Tyr Leu 
    1115                 1120                 1125             


Ile Ser  Asp Asn Leu Glu Gln  Pro Met Gly Ser Ser  His Ala Ser 
    1130                 1135                 1140             


Gln Val  Cys Ser Glu Thr Pro  Asp Asp Leu Leu Asp  Asp Gly Glu 
    1145                 1150                 1155             


Ile Lys  Glu Asp Thr Ser Phe  Ala Glu Asn Asp Ile  Lys Glu Ser 
    1160                 1165                 1170             


Ser Ala  Val Phe Ser Lys Ser  Val Gln Lys Gly Glu  Leu Ser Arg 
    1175                 1180                 1185             


Ser Pro  Ser Pro Phe Thr His  Thr His Leu Ala Gln  Gly Tyr Arg 
    1190                 1195                 1200             


Arg Gly  Ala Lys Lys Leu Glu  Ser Ser Glu Glu Asn  Leu Ser Ser 
    1205                 1210                 1215             


Glu Asp  Glu Glu Leu Pro Cys  Phe Gln His Leu Leu  Phe Gly Lys 
    1220                 1225                 1230             


Val Asn  Asn Ile Pro Ser Gln  Ser Thr Arg His Ser  Thr Val Ala 
    1235                 1240                 1245             


Thr Glu  Cys Leu Ser Lys Asn  Thr Glu Glu Asn Leu  Leu Ser Leu 
    1250                 1255                 1260             


Lys Asn  Ser Leu Asn Asp Cys  Ser Asn Gln Val Ile  Leu Ala Lys 
    1265                 1270                 1275             


Ala Ser  Gln Glu His His Leu  Ser Glu Glu Thr Lys  Cys Ser Ala 
    1280                 1285                 1290             


Ser Leu  Phe Ser Ser Gln Cys  Ser Glu Leu Glu Asp  Leu Thr Ala 
    1295                 1300                 1305             


Asn Thr  Asn Thr Gln Asp Pro  Phe Leu Ile Gly Ser  Ser Lys Gln 
    1310                 1315                 1320             


Met Arg  His Gln Ser Glu Ser  Gln Gly Val Gly Leu  Ser Asp Lys 
    1325                 1330                 1335             


Glu Leu  Val Ser Asp Asp Glu  Glu Arg Gly Thr Gly  Leu Glu Glu 
    1340                 1345                 1350             


Asn Asn  Gln Glu Glu Gln Ser  Met Asp Ser Asn Leu  Gly Glu Ala 
    1355                 1360                 1365             


Ala Ser  Gly Cys Glu Ser Glu  Thr Ser Val Ser Glu  Asp Cys Ser 
    1370                 1375                 1380             


Gly Leu  Ser Ser Gln Ser Asp  Ile Leu Thr Thr Gln  Gln Arg Asp 
    1385                 1390                 1395             


Thr Met  Gln His Asn Leu Ile  Lys Leu Gln Gln Glu  Met Ala Glu 
    1400                 1405                 1410             


Leu Glu  Ala Val Leu Glu Gln  His Gly Ser Gln Pro  Ser Asn Ser 
    1415                 1420                 1425             


Tyr Pro  Ser Ile Ile Ser Asp  Ser Ser Ala Leu Glu  Asp Leu Arg 
    1430                 1435                 1440             


Asn Pro  Glu Gln Ser Thr Ser  Glu Lys Ala Val Leu  Thr Ser Gln 
    1445                 1450                 1455             


Lys Ser  Ser Glu Tyr Pro Ile  Ser Gln Asn Pro Glu  Gly Leu Ser 
    1460                 1465                 1470             


Ala Asp  Lys Phe Glu Val Ser  Ala Asp Ser Ser Thr  Ser Lys Asn 
    1475                 1480                 1485             


Lys Glu  Pro Gly Val Glu Arg  Ser Ser Pro Ser Lys  Cys Pro Ser 
    1490                 1495                 1500             


Leu Asp  Asp Arg Trp Tyr Met  His Ser Cys Ser Gly  Ser Leu Gln 
    1505                 1510                 1515             


Asn Arg  Asn Tyr Pro Ser Gln  Glu Glu Leu Ile Lys  Val Val Asp 
    1520                 1525                 1530             


Val Glu  Glu Gln Gln Leu Glu  Glu Ser Gly Pro His  Asp Leu Thr 
    1535                 1540                 1545             


Glu Thr  Ser Tyr Leu Pro Arg  Gln Asp Leu Glu Gly  Thr Pro Tyr 
    1550                 1555                 1560             


Leu Glu  Ser Gly Ile Ser Leu  Phe Ser Asp Asp Pro  Glu Ser Asp 
    1565                 1570                 1575             


Pro Ser  Glu Asp Arg Ala Pro  Glu Ser Ala Arg Val  Gly Asn Ile 
    1580                 1585                 1590             


Pro Ser  Ser Thr Ser Ala Leu  Lys Val Pro Gln Leu  Lys Val Ala 
    1595                 1600                 1605             


Glu Ser  Ala Gln Ser Pro Ala  Ala Ala His Thr Thr  Asp Thr Ala 
    1610                 1615                 1620             


Gly Tyr  Asn Ala Met Glu Glu  Ser Val Ser Arg Glu  Lys Pro Glu 
    1625                 1630                 1635             


Leu Thr  Ala Ser Thr Glu Arg  Val Asn Lys Arg Met  Ser Met Val 
    1640                 1645                 1650             


Val Ser  Gly Leu Thr Pro Glu  Glu Phe Met Leu Val  Tyr Lys Phe 
    1655                 1660                 1665             


Ala Arg  Lys His His Ile Thr  Leu Thr Asn Leu Ile  Thr Glu Glu 
    1670                 1675                 1680             


Thr Thr  His Val Val Met Lys  Thr Asp Ala Glu Phe  Val Cys Glu 
    1685                 1690                 1695             


Arg Thr  Leu Lys Tyr Phe Leu  Gly Ile Ala Gly Gly  Lys Trp Val 
    1700                 1705                 1710             


Val Ser  Tyr Phe Trp Val Thr  Gln Ser Ile Lys Glu  Arg Lys Met 
    1715                 1720                 1725             


Leu Asn  Glu His Asp Phe Glu  Val Arg Gly Asp Val  Val Asn Gly 
    1730                 1735                 1740             


Arg Asn  His Gln Gly Pro Lys  Arg Ala Arg Glu Ser  Gln Asp Arg 
    1745                 1750                 1755             


Lys Ile  Phe Arg Gly Leu Glu  Ile Cys Cys Tyr Gly  Pro Phe Thr 
    1760                 1765                 1770             


Asn Met  Pro Thr Asp Gln Leu  Glu Trp Met Val Gln  Leu Cys Gly 
    1775                 1780                 1785             


Ala Ser  Val Val Lys Glu Leu  Ser Ser Phe Thr Leu  Gly Thr Gly 
    1790                 1795                 1800             


Val His  Pro Ile Val Val Val  Gln Pro Asp Ala Trp  Thr Glu Asp 
    1805                 1810                 1815             


Asn Gly  Phe His Ala Ile Gly  Gln Met Cys Glu Ala  Pro Val Val 
    1820                 1825                 1830             


Thr Arg  Glu Trp Val Leu Asp  Ser Val Ala Leu Tyr  Gln Cys Gln 
    1835                 1840                 1845             


Glu Leu  Asp Thr Tyr Leu Ile  Pro Gln Ile Pro His  Ser His Tyr 
    1850                 1855                 1860             


<210>  1086
<211>  550
<212>  PRT
<213>  Human

<400>  1086

Met Lys Trp Glu Glu Tyr Glu Glu Leu Leu His Tyr Ala Ile Val Thr 
1               5                   10                  15      


Pro Asn Ile Glu Pro Cys Ala Ser Gln Ser Ser His Pro Lys Gly Glu 
            20                  25                  30          


Leu Val Pro Asp Val Arg Ile Ser Thr Ile His Asp Ile Leu His Ser 
        35                  40                  45              


Gln Gly Asn Asn Ser Glu Val Arg Glu Thr Ala Ile Glu Val Gly Lys 
    50                  55                  60                  


Gly Cys Asp Phe His Ile Ser Ser His Ser Lys Thr Asp Glu Ser Ser 
65                  70                  75                  80  


Pro Val Leu Ser Pro Arg Lys Pro Ser His Pro Val Met Asp Phe Phe 
                85                  90                  95      


Ser Ser His Leu Leu Ala Asp Ser Ser Ser Pro Ala Thr Asn Ser Ser 
            100                 105                 110         


His Thr Asp Ala His Glu Ile Leu Val Ser Asp Phe Leu Val Ser Asp 
        115                 120                 125             


Glu Asn Leu Gln Lys Met Glu Asn Val Leu Asp Leu Trp Ser Ser Gly 
    130                 135                 140                 


Leu Lys Thr Asn Ile Ile Ser Glu Leu Ser Lys Trp Arg Leu Asn Phe 
145                 150                 155                 160 


Ile Asp Trp His Arg Met Glu Met Arg Lys Glu Lys Glu Lys His Ala 
                165                 170                 175     


Ala His Leu Lys Gln Leu Cys Asn Gln Ile Asn Glu Leu Lys Glu Leu 
            180                 185                 190         


Gln Lys Thr Phe Glu Ile Ser Ile Gly Arg Lys Asp Glu Val Ile Ser 
        195                 200                 205             


Ser Leu Ser His Ala Ile Gly Lys Gln Lys Glu Lys Ile Glu Leu Met 
    210                 215                 220                 


Arg Thr Phe Phe His Trp Arg Ile Gly His Val Arg Ala Arg Gln Asp 
225                 230                 235                 240 


Val Tyr Glu Gly Lys Leu Ala Asp Gln Tyr Tyr Gln Arg Thr Leu Leu 
                245                 250                 255     


Lys Lys Val Trp Lys Val Trp Arg Ser Val Val Gln Lys Gln Trp Lys 
            260                 265                 270         


Asp Val Val Glu Arg Ala Cys Gln Ala Arg Ala Glu Glu Val Cys Ile 
        275                 280                 285             


Gln Ile Ser Asn Asp Tyr Glu Ala Lys Val Ala Met Leu Ser Gly Ala 
    290                 295                 300                 


Leu Glu Asn Ala Lys Ala Glu Ile Gln Arg Met Gln His Glu Lys Glu 
305                 310                 315                 320 


His Phe Glu Asp Ser Met Lys Lys Ala Phe Met Arg Gly Val Cys Ala 
                325                 330                 335     


Leu Asn Leu Glu Ala Met Thr Ile Phe Gln Asn Arg Asn Asp Ala Gly 
            340                 345                 350         


Ile Asp Ser Thr Asn Asn Lys Lys Glu Glu Tyr Gly Pro Gly Val Gln 
        355                 360                 365             


Gly Lys Glu His Ser Ala His Leu Asp Pro Ser Ala Pro Pro Met Pro 
    370                 375                 380                 


Leu Pro Val Thr Ser Pro Leu Leu Pro Ser Pro Pro Ala Ala Val Gly 
385                 390                 395                 400 


Gly Ala Ser Ala Thr Ala Val Pro Ser Ala Ala Ser Met Thr Ser Thr 
                405                 410                 415     


Arg Ala Ala Ser Ala Ser Ser Val His Val Pro Val Ser Ala Leu Gly 
            420                 425                 430         


Ala Gly Ser Ala Ala Thr Ala Ala Ser Glu Glu Met Tyr Val Pro Arg 
        435                 440                 445             


Val Val Thr Ser Ala Gln Gln Lys Ala Gly Arg Thr Ile Thr Ala Arg 
    450                 455                 460                 


Ile Thr Gly Arg Cys Asp Phe Ala Ser Lys Asn Arg Ile Ser Ser Ser 
465                 470                 475                 480 


Leu Ala Ile Met Gly Val Ser Pro Pro Met Ser Ser Val Val Val Glu 
                485                 490                 495     


Lys His His Pro Val Thr Val Gln Thr Ile Pro Gln Ala Thr Ala Ala 
            500                 505                 510         


Lys Tyr Pro Arg Thr Ile His Pro Glu Ser Ser Thr Ser Ala Ser Arg 
        515                 520                 525             


Ser Leu Gly Thr Arg Ser Ala His Thr Gln Ser Leu Thr Ser Val His 
    530                 535                 540                 


Ser Ile Lys Val Val Asp 
545                 550 


<210>  1087
<211>  167
<212>  PRT
<213>  Human

<400>  1087

Met Gly Asn Cys Val Lys Tyr Pro Leu Arg Asn Leu Ser Arg Lys Asp 
1               5                   10                  15      


Arg Ser Leu Arg Pro Glu Glu Ile Glu Glu Leu Arg Glu Ala Phe Arg 
            20                  25                  30          


Glu Phe Asp Lys Asp Lys Asp Gly Tyr Ile Asn Cys Arg Asp Leu Gly 
        35                  40                  45              


Asn Cys Met Arg Thr Met Gly Tyr Met Pro Thr Glu Met Glu Leu Ile 
    50                  55                  60                  


Glu Leu Ser Gln Gln Ile Asn Met Asn Leu Gly Gly His Val Asp Phe 
65                  70                  75                  80  


Asp Asp Phe Val Glu Leu Met Gly Pro Lys Leu Leu Ala Glu Thr Ala 
                85                  90                  95      


Asp Met Ile Gly Val Lys Glu Leu Arg Asp Ala Phe Arg Glu Phe Asp 
            100                 105                 110         


Thr Asn Gly Asp Gly Glu Ile Ser Thr Ser Glu Leu Arg Glu Ala Met 
        115                 120                 125             


Arg Lys Leu Leu Gly His Gln Val Gly His Arg Asp Ile Glu Glu Ile 
    130                 135                 140                 


Ile Arg Asp Val Asp Leu Asn Gly Asp Gly Arg Val Asp Phe Glu Glu 
145                 150                 155                 160 


Phe Val Arg Met Met Ser Arg 
                165         


<210>  1088
<211>  378
<212>  PRT
<213>  Human

<400>  1088

Met Ser Gly Ala Gly Val Ala Ala Gly Thr Arg Pro Pro Ser Ser Pro 
1               5                   10                  15      


Thr Pro Gly Ser Arg Arg Arg Arg Gln Arg Pro Ser Val Gly Val Gln 
            20                  25                  30          


Ser Leu Arg Pro Gln Ser Pro Gln Leu Arg Gln Ser Asp Pro Gln Lys 
        35                  40                  45              


Arg Asn Leu Asp Leu Glu Lys Ser Leu Gln Phe Leu Gln Gln Gln His 
    50                  55                  60                  


Ser Glu Met Leu Ala Lys Leu His Glu Glu Ile Glu His Leu Lys Arg 
65                  70                  75                  80  


Glu Asn Lys Asp Leu His Tyr Lys Leu Ile Met Asn Gln Thr Ser Gln 
                85                  90                  95      


Lys Lys Asp Gly Pro Ser Gly Asn His Leu Ser Arg Ala Ser Ala Pro 
            100                 105                 110         


Leu Gly Ala Arg Trp Val Cys Ile Asn Gly Val Trp Val Glu Pro Gly 
        115                 120                 125             


Gly Pro Ser Pro Ala Arg Leu Lys Glu Gly Ser Ser Arg Thr His Arg 
    130                 135                 140                 


Pro Gly Gly Lys Arg Gly Arg Leu Ala Gly Gly Ser Ala Asp Thr Val 
145                 150                 155                 160 


Arg Ser Pro Ala Asp Ser Leu Ser Met Ser Ser Phe Gln Ser Val Lys 
                165                 170                 175     


Ser Ile Ser Asn Ser Gly Lys Ala Arg Pro Gln Pro Gly Ser Phe Asn 
            180                 185                 190         


Lys Gln Asp Ser Lys Ala Asp Val Ser Gln Lys Ala Asp Leu Glu Glu 
        195                 200                 205             


Glu Pro Leu Leu His Asn Ser Lys Leu Asp Lys Val Pro Gly Val Gln 
    210                 215                 220                 


Gly Gln Ala Arg Lys Glu Lys Ala Glu Ala Ser Asn Ala Gly Ala Ala 
225                 230                 235                 240 


Cys Met Gly Asn Ser Gln His Gln Gly Arg Gln Met Gly Ala Gly Ala 
                245                 250                 255     


His Pro Pro Met Ile Leu Pro Leu Pro Leu Arg Lys Pro Thr Thr Leu 
            260                 265                 270         


Arg Gln Cys Glu Val Leu Ile Arg Glu Leu Trp Asn Thr Asn Leu Leu 
        275                 280                 285             


Gln Thr Gln Glu Leu Arg His Leu Lys Ser Leu Leu Glu Gly Ser Gln 
    290                 295                 300                 


Arg Pro Gln Ala Ala Pro Glu Glu Ala Ser Phe Pro Arg Asp Gln Glu 
305                 310                 315                 320 


Ala Thr His Phe Pro Lys Val Ser Thr Lys Ser Leu Ser Lys Lys Cys 
                325                 330                 335     


Leu Ser Pro Pro Val Ala Glu Arg Ala Ile Leu Pro Ala Leu Lys Gln 
            340                 345                 350         


Thr Pro Lys Asn Asn Phe Ala Glu Arg Gln Lys Arg Leu Gln Ala Met 
        355                 360                 365             


Gln Lys Arg Arg Leu His Arg Ser Val Leu 
    370                 375             


<210>  1089
<211>  274
<212>  PRT
<213>  Human

<400>  1089

Met Ala Ser Asp Ser Gly Asn Gln Gly Thr Leu Cys Thr Leu Glu Phe 
1               5                   10                  15      


Ala Val Gln Met Thr Cys Gln Ser Cys Val Asp Ala Val Arg Lys Ser 
            20                  25                  30          


Leu Gln Gly Val Ala Gly Val Gln Asp Val Glu Val His Leu Glu Asp 
        35                  40                  45              


Gln Met Val Leu Val His Thr Thr Leu Pro Ser Gln Glu Val Gln Ala 
    50                  55                  60                  


Leu Leu Glu Gly Thr Gly Arg Gln Ala Val Leu Lys Gly Met Gly Ser 
65                  70                  75                  80  


Gly Gln Leu Gln Asn Leu Gly Ala Ala Val Ala Ile Leu Gly Gly Pro 
                85                  90                  95      


Gly Thr Val Gln Gly Val Val Arg Phe Leu Gln Leu Thr Pro Glu Arg 
            100                 105                 110         


Cys Leu Ile Glu Gly Thr Ile Asp Gly Leu Glu Pro Gly Leu His Gly 
        115                 120                 125             


Leu His Val His Gln Tyr Gly Asp Leu Thr Asn Asn Cys Asn Ser Cys 
    130                 135                 140                 


Gly Asn His Phe Asn Pro Asp Gly Ala Ser His Gly Gly Pro Gln Asp 
145                 150                 155                 160 


Ser Asp Arg His Arg Gly Asp Leu Gly Asn Val Arg Ala Asp Ala Asp 
                165                 170                 175     


Gly Arg Ala Ile Phe Arg Met Glu Asp Glu Gln Leu Lys Val Trp Asp 
            180                 185                 190         


Val Ile Gly Arg Ser Leu Ile Ile Asp Glu Gly Glu Asp Asp Leu Gly 
        195                 200                 205             


Arg Gly Gly His Pro Leu Ser Lys Ile Thr Gly Asn Ser Gly Glu Arg 
    210                 215                 220                 


Leu Ala Cys Gly Ile Ile Ala Arg Ser Ala Gly Leu Phe Gln Asn Pro 
225                 230                 235                 240 


Lys Gln Ile Cys Ser Cys Asp Gly Leu Thr Ile Trp Glu Glu Arg Gly 
                245                 250                 255     


Arg Pro Ile Ala Gly Lys Gly Arg Lys Glu Ser Ala Gln Pro Pro Ala 
            260                 265                 270         


His Leu 
        


<210>  1090
<211>  175
<212>  PRT
<213>  Human

<400>  1090

Met Asp Ile Ala Ile His His Pro Trp Ile Arg Arg Pro Phe Phe Pro 
1               5                   10                  15      


Phe His Ser Pro Ser Arg Leu Phe Asp Gln Phe Phe Gly Glu His Leu 
            20                  25                  30          


Leu Glu Ser Asp Leu Phe Pro Thr Ser Thr Ser Leu Ser Pro Phe Tyr 
        35                  40                  45              


Leu Arg Pro Pro Ser Phe Leu Arg Ala Pro Ser Trp Phe Asp Thr Gly 
    50                  55                  60                  


Leu Ser Glu Met Arg Leu Glu Lys Asp Arg Phe Ser Val Asn Leu Asp 
65                  70                  75                  80  


Val Lys His Phe Ser Pro Glu Glu Leu Lys Val Lys Val Leu Gly Asp 
                85                  90                  95      


Val Ile Glu Val His Gly Lys His Glu Glu Arg Gln Asp Glu His Gly 
            100                 105                 110         


Phe Ile Ser Arg Glu Phe His Arg Lys Tyr Arg Ile Pro Ala Asp Val 
        115                 120                 125             


Asp Pro Leu Thr Ile Thr Ser Ser Leu Ser Ser Asp Gly Val Leu Thr 
    130                 135                 140                 


Val Asn Gly Pro Arg Lys Gln Val Ser Gly Pro Glu Arg Thr Ile Pro 
145                 150                 155                 160 


Ile Thr Arg Glu Glu Lys Pro Ala Val Thr Ala Ala Pro Lys Lys 
                165                 170                 175 


<210>  1091
<211>  582
<212>  PRT
<213>  Human

<400>  1091

Met Glu Ala Leu Ser Arg Ala Gly Gln Glu Met Ser Leu Ala Ala Leu 
1               5                   10                  15      


Lys Gln His Asp Pro Tyr Ile Thr Ser Ile Ala Asp Leu Thr Gly Gln 
            20                  25                  30          


Val Ala Leu Tyr Thr Phe Cys Pro Lys Ala Asn Gln Trp Glu Lys Thr 
        35                  40                  45              


Asp Ile Glu Gly Thr Leu Phe Val Tyr Arg Arg Ser Ala Ser Pro Tyr 
    50                  55                  60                  


His Gly Phe Thr Ile Val Asn Arg Leu Asn Met His Asn Leu Val Glu 
65                  70                  75                  80  


Pro Val Asn Lys Asp Leu Glu Phe Gln Leu His Glu Pro Phe Leu Leu 
                85                  90                  95      


Tyr Arg Asn Ala Ser Leu Ser Ile Tyr Ser Ile Trp Phe Tyr Asp Lys 
            100                 105                 110         


Asn Asp Cys His Arg Ile Ala Lys Leu Met Ala Asp Val Val Glu Glu 
        115                 120                 125             


Glu Thr Arg Arg Ser Gln Gln Ala Ala Arg Asp Lys Gln Ser Pro Ser 
    130                 135                 140                 


Gln Ala Asn Gly Cys Ser Asp His Arg Pro Ile Asp Ile Leu Glu Met 
145                 150                 155                 160 


Leu Ser Arg Ala Lys Asp Glu Tyr Glu Arg Asn Gln Met Gly Asp Ser 
                165                 170                 175     


Asn Ile Ser Ser Pro Gly Leu Gln Pro Ser Thr Gln Leu Ser Asn Leu 
            180                 185                 190         


Gly Ser Thr Glu Thr Leu Glu Glu Met Pro Ser Gly Ser Gln Asp Lys 
        195                 200                 205             


Ser Ala Pro Ser Gly His Lys His Leu Thr Val Glu Glu Leu Phe Gly 
    210                 215                 220                 


Thr Ser Leu Pro Lys Glu Gln Pro Ala Val Val Gly Leu Asp Ser Glu 
225                 230                 235                 240 


Glu Met Glu Arg Leu Pro Gly Asp Ala Ser Gln Lys Glu Pro Asn Ser 
                245                 250                 255     


Phe Leu Pro Phe Pro Phe Glu Gln Leu Gly Gly Ala Pro Gln Ser Glu 
            260                 265                 270         


Thr Leu Gly Val Pro Ser Ala Ala His His Ser Val Gln Pro Glu Ile 
        275                 280                 285             


Thr Thr Pro Val Leu Ile Thr Pro Ala Ser Ile Thr Gln Ser Asn Glu 
    290                 295                 300                 


Lys His Ala Pro Thr Tyr Thr Ile Pro Leu Ser Pro Val Leu Ser Pro 
305                 310                 315                 320 


Thr Leu Pro Ala Glu Ala Pro Thr Ala Gln Val Pro Pro Ser Leu Pro 
                325                 330                 335     


Arg Asn Ser Thr Met Met Gln Ala Val Lys Thr Thr Pro Arg Gln Arg 
            340                 345                 350         


Ser Pro Leu Leu Asn Gln Pro Val Pro Glu Leu Ser His Ala Ser Leu 
        355                 360                 365             


Ile Ala Asn Gln Ser Pro Phe Arg Ala Pro Leu Asn Val Thr Asn Thr 
    370                 375                 380                 


Ala Gly Thr Ser Leu Pro Ser Val Asp Leu Leu Gln Lys Leu Arg Leu 
385                 390                 395                 400 


Thr Pro Gln His Asp Gln Ile Gln Thr Gln Pro Leu Gly Lys Gly Ala 
                405                 410                 415     


Met Val Ala Ser Phe Ser Pro Ala Ala Gly Gln Leu Ala Thr Pro Glu 
            420                 425                 430         


Ser Phe Ile Glu Pro Pro Ser Lys Thr Ala Ala Ala Arg Val Ala Ala 
        435                 440                 445             


Ser Ala Ser Leu Ser Asn Met Val Leu Ala Pro Leu Gln Ser Met Gln 
    450                 455                 460                 


Gln Asn Gln Asp Pro Glu Val Phe Val Gln Pro Lys Val Leu Ser Ser 
465                 470                 475                 480 


Ala Ile Gln Val Ala Gly Ala Pro Leu Val Thr Ala Thr Thr Thr Ala 
                485                 490                 495     


Val Ser Ser Val Leu Leu Ala Pro Ser Val Phe Gln Gln Thr Val Thr 
            500                 505                 510         


Arg Ser Ser Asp Leu Glu Arg Lys Ala Ser Ser Pro Ser Pro Leu Thr 
        515                 520                 525             


Ile Gly Thr Pro Glu Ser Gln Arg Lys Pro Ser Ile Ile Leu Ser Lys 
    530                 535                 540                 


Ser Gln Leu Gln Asp Thr Leu Ile His Leu Ile Lys Asn Asp Ser Ser 
545                 550                 555                 560 


Phe Leu Ser Thr Leu His Glu Val Tyr Leu Gln Val Leu Thr Lys Asn 
                565                 570                 575     


Lys Asp Asn His Asn Leu 
            580         


<210>  1092
<211>  495
<212>  PRT
<213>  Human

<400>  1092

Met Arg Leu Thr Arg Cys Gln Ala Ala Leu Ala Ala Ala Ile Thr Leu 
1               5                   10                  15      


Asn Leu Leu Val Leu Phe Tyr Val Ser Trp Leu Gln His Gln Pro Arg 
            20                  25                  30          


Asn Ser Arg Ala Arg Gly Pro Arg Arg Ala Ser Ala Ala Gly Pro Arg 
        35                  40                  45              


Val Thr Val Leu Val Arg Glu Phe Glu Ala Phe Asp Asn Ala Val Pro 
    50                  55                  60                  


Glu Leu Val Asp Ser Phe Leu Gln Gln Asp Pro Ala Gln Pro Val Val 
65                  70                  75                  80  


Val Ala Ala Asp Thr Leu Pro Tyr Pro Pro Leu Ala Leu Pro Arg Ile 
                85                  90                  95      


Pro Asn Val Arg Leu Ala Leu Leu Gln Pro Ala Leu Asp Arg Pro Ala 
            100                 105                 110         


Ala Ala Ser Arg Pro Glu Thr Tyr Val Ala Thr Glu Phe Val Ala Leu 
        115                 120                 125             


Val Pro Asp Gly Ala Arg Ala Glu Ala Pro Gly Leu Leu Glu Arg Met 
    130                 135                 140                 


Val Glu Ala Leu Arg Ala Gly Ser Ala Arg Leu Val Ala Ala Pro Val 
145                 150                 155                 160 


Ala Thr Ala Asn Pro Ala Arg Cys Leu Ala Leu Asn Val Ser Leu Arg 
                165                 170                 175     


Glu Trp Thr Ala Arg Tyr Gly Ala Ala Pro Ala Ala Pro Arg Cys Asp 
            180                 185                 190         


Ala Leu Asp Gly Asp Ala Val Val Leu Leu Arg Ala Arg Asp Leu Phe 
        195                 200                 205             


Asn Leu Ser Ala Pro Leu Ala Arg Pro Val Gly Thr Ser Leu Phe Leu 
    210                 215                 220                 


Gln Thr Ala Leu Arg Gly Trp Ala Val Gln Leu Leu Asp Leu Thr Phe 
225                 230                 235                 240 


Ala Ala Ala Arg Gln Pro Pro Leu Ala Thr Ala His Ala Arg Trp Lys 
                245                 250                 255     


Ala Glu Arg Glu Gly Arg Ala Arg Arg Ala Ala Leu Leu Arg Ala Leu 
            260                 265                 270         


Gly Ile Arg Leu Val Ser Trp Glu Gly Gly Arg Leu Glu Trp Phe Gly 
        275                 280                 285             


Cys Asn Lys Glu Thr Thr Arg Cys Phe Gly Thr Val Val Gly Asp Thr 
    290                 295                 300                 


Pro Ala Tyr Leu Tyr Glu Glu Arg Trp Thr Pro Pro Cys Cys Leu Arg 
305                 310                 315                 320 


Ala Leu Arg Glu Thr Ala Arg Tyr Val Val Gly Val Leu Glu Ala Ala 
                325                 330                 335     


Gly Val Arg Tyr Trp Leu Glu Gly Gly Ser Leu Leu Gly Ala Ala Arg 
            340                 345                 350         


His Gly Asp Ile Ile Pro Trp Asp Tyr Asp Val Asp Leu Gly Ile Tyr 
        355                 360                 365             


Leu Glu Asp Val Gly Asn Cys Glu Gln Leu Arg Gly Ala Glu Ala Gly 
    370                 375                 380                 


Ser Val Val Asp Glu Arg Gly Phe Val Trp Glu Lys Ala Val Glu Gly 
385                 390                 395                 400 


Asp Phe Phe Arg Val Gln Tyr Ser Glu Ser Asn His Leu His Val Asp 
                405                 410                 415     


Leu Trp Pro Phe Tyr Pro Arg Asn Gly Val Met Thr Lys Asp Thr Trp 
            420                 425                 430         


Leu Asp His Arg Gln Asp Val Glu Phe Pro Glu His Phe Leu Gln Pro 
        435                 440                 445             


Leu Val Pro Leu Pro Phe Ala Gly Phe Val Ala Gln Ala Pro Asn Asn 
    450                 455                 460                 


Tyr Arg Arg Phe Leu Glu Leu Lys Phe Gly Pro Gly Val Ile Glu Asn 
465                 470                 475                 480 


Pro Gln Tyr Pro Asn Pro Ala Leu Leu Ser Leu Thr Gly Ser Gly 
                485                 490                 495 


<210>  1093
<211>  621
<212>  PRT
<213>  Human

<400>  1093

Met Ala Asn Val Pro Trp Ala Glu Val Cys Glu Lys Phe Gln Ala Ala 
1               5                   10                  15      


Leu Ala Leu Ser Arg Val Glu Leu His Lys Asn Pro Glu Lys Glu Pro 
            20                  25                  30          


Tyr Lys Ser Lys Tyr Ser Ala Arg Ala Leu Leu Glu Glu Val Lys Ala 
        35                  40                  45              


Leu Leu Gly Pro Ala Pro Glu Asp Glu Asp Glu Arg Pro Glu Ala Glu 
    50                  55                  60                  


Asp Gly Pro Gly Ala Gly Asp His Ala Leu Gly Leu Pro Ala Glu Val 
65                  70                  75                  80  


Val Glu Pro Glu Gly Pro Val Ala Gln Arg Ala Val Arg Leu Ala Val 
                85                  90                  95      


Ile Glu Phe His Leu Gly Val Asn His Ile Asp Thr Glu Glu Leu Ser 
            100                 105                 110         


Ala Gly Glu Glu His Leu Val Lys Cys Leu Arg Leu Leu Arg Arg Tyr 
        115                 120                 125             


Arg Leu Ser His Asp Cys Ile Ser Leu Cys Ile Gln Ala Gln Asn Asn 
    130                 135                 140                 


Leu Gly Ile Leu Trp Ser Glu Arg Glu Glu Ile Glu Thr Ala Gln Ala 
145                 150                 155                 160 


Tyr Leu Glu Ser Ser Glu Ala Leu Tyr Asn Gln Tyr Met Lys Glu Val 
                165                 170                 175     


Gly Ser Pro Pro Leu Asp Pro Thr Glu Arg Phe Leu Pro Glu Glu Glu 
            180                 185                 190         


Lys Leu Thr Glu Gln Glu Arg Ser Lys Arg Phe Glu Lys Val Tyr Thr 
        195                 200                 205             


His Asn Leu Tyr Tyr Leu Ala Gln Val Tyr Gln His Leu Glu Met Phe 
    210                 215                 220                 


Glu Lys Ala Ala His Tyr Cys His Ser Thr Leu Lys Arg Gln Leu Glu 
225                 230                 235                 240 


His Asn Ala Tyr His Pro Ile Glu Trp Ala Ile Asn Ala Ala Thr Leu 
                245                 250                 255     


Ser Gln Phe Tyr Ile Asn Lys Leu Cys Phe Met Glu Ala Arg His Cys 
            260                 265                 270         


Leu Ser Ala Ala Asn Val Ile Phe Gly Gln Thr Gly Lys Ile Ser Ala 
        275                 280                 285             


Thr Glu Asp Thr Pro Glu Ala Glu Gly Glu Val Pro Glu Leu Tyr His 
    290                 295                 300                 


Gln Arg Lys Gly Glu Ile Ala Arg Cys Trp Ile Lys Tyr Cys Leu Thr 
305                 310                 315                 320 


Leu Met Gln Asn Ala Gln Leu Ser Met Gln Asp Asn Ile Gly Glu Leu 
                325                 330                 335     


Asp Leu Asp Lys Gln Ser Glu Leu Arg Ala Leu Arg Lys Lys Glu Leu 
            340                 345                 350         


Asp Glu Glu Glu Ser Ile Arg Lys Lys Ala Val Gln Phe Gly Thr Gly 
        355                 360                 365             


Glu Leu Cys Asp Ala Ile Ser Ala Val Glu Glu Lys Val Ser Tyr Leu 
    370                 375                 380                 


Arg Pro Leu Asp Phe Glu Glu Ala Arg Glu Leu Phe Leu Leu Gly Gln 
385                 390                 395                 400 


His Tyr Val Phe Glu Ala Lys Glu Phe Phe Gln Ile Asp Gly Tyr Val 
                405                 410                 415     


Thr Asp His Ile Glu Val Val Gln Asp His Ser Ala Leu Phe Lys Val 
            420                 425                 430         


Leu Ala Phe Phe Glu Thr Asp Met Glu Arg Arg Cys Lys Met His Lys 
        435                 440                 445             


Arg Arg Ile Ala Met Leu Glu Pro Leu Thr Val Asp Leu Asn Pro Gln 
    450                 455                 460                 


Tyr Tyr Leu Leu Val Asn Arg Gln Ile Gln Phe Glu Ile Ala His Ala 
465                 470                 475                 480 


Tyr Tyr Asp Met Met Asp Leu Lys Val Ala Ile Ala Asp Arg Leu Arg 
                485                 490                 495     


Asp Pro Asp Ser His Ile Val Lys Lys Ile Asn Asn Leu Asn Lys Ser 
            500                 505                 510         


Ala Leu Lys Tyr Tyr Gln Leu Phe Leu Asp Ser Leu Arg Asp Pro Asn 
        515                 520                 525             


Lys Val Phe Pro Glu His Ile Gly Glu Asp Val Leu Arg Pro Ala Met 
    530                 535                 540                 


Leu Ala Lys Phe Arg Val Ala Arg Leu Tyr Gly Lys Ile Ile Thr Ala 
545                 550                 555                 560 


Asp Pro Lys Lys Glu Leu Glu Asn Leu Ala Thr Ser Leu Glu His Tyr 
                565                 570                 575     


Lys Phe Ile Val Asp Tyr Cys Glu Lys His Pro Glu Ala Ala Gln Glu 
            580                 585                 590         


Ile Glu Val Glu Leu Glu Leu Ser Lys Glu Met Val Ser Leu Leu Pro 
        595                 600                 605             


Thr Lys Met Glu Arg Phe Arg Thr Lys Met Ala Leu Thr 
    610                 615                 620     


<210>  1094
<211>  1359
<212>  PRT
<213>  Human

<400>  1094

Met Tyr Ser Val Glu Asp Leu Leu Ile Ser His Gly Tyr Lys Leu Ser 
1               5                   10                  15      


Arg Asp Pro Pro Ala Ser Arg Glu Asp Asn Pro Lys Gly Arg Gln Ala 
            20                  25                  30          


Ala Arg Thr Gly Thr Arg Ala Gly Gln Gly Leu Gln Asn Gly His Glu 
        35                  40                  45              


Asp Gly Pro Ala Ala Leu Ala His Arg Lys Thr Ser Ala Gly Lys Gly 
    50                  55                  60                  


His Val Ser Asp Ser Glu Ser Arg Arg Ser Thr Pro Arg Gly His Gly 
65                  70                  75                  80  


Glu Pro Gln Ser Thr Ser Ala Ser Arg Thr Ser Glu Ala Gly Phe Cys 
                85                  90                  95      


Asn Gln Pro Pro Ser Ala Trp Ser Ser His Pro Pro Thr Gly Asn Asp 
            100                 105                 110         


Gln Ala Tyr Arg Arg Arg Gly Arg Gln Glu Ala Arg Ser Gln Lys Pro 
        115                 120                 125             


Arg Glu His Glu Asn Leu Glu Ala Arg Gly Met Ala Gln Ala His Ser 
    130                 135                 140                 


Leu Pro Val His Val Arg Glu Gly Pro Trp Glu Val Gly Gly Arg Ser 
145                 150                 155                 160 


Glu His Val Met Lys Lys Pro Val Trp Glu Glu Glu Leu Arg Met Ser 
                165                 170                 175     


Gly Pro Ala Lys Trp Gln Asn Val Ser Leu Glu Ser Trp Asn Gln Pro 
            180                 185                 190         


Arg Lys Leu Gly Arg Gln Met Ser Asp Gly Asp Gly Glu Arg Leu Phe 
        195                 200                 205             


Gln Asp Leu Tyr Pro Phe Ile Gln Gly Glu His Val Leu Asn Ser Gln 
    210                 215                 220                 


Asn Lys Gly Lys Ser Arg Ser Leu Pro Arg Val Leu Ser Pro Glu Ser 
225                 230                 235                 240 


Leu Ser Cys Thr Glu Ile Pro Ile Pro Leu Asn Glu Arg His Ser Pro 
                245                 250                 255     


Lys Met Pro Pro Tyr Pro Pro Thr Cys Ala Pro Asn Leu Asp Ser Thr 
            260                 265                 270         


Arg Asn Ser Glu Lys Ser Gly Cys Ser Ala Pro Phe Pro Arg Pro Lys 
        275                 280                 285             


Phe Gly Arg Pro Leu Lys Pro Pro Ser Tyr Ser Ser His Gln Gln Ser 
    290                 295                 300                 


Arg Gly Gly Ala Asp Ser Ser Asp Ser Gln Asp Ser Gln Gln Met Asp 
305                 310                 315                 320 


Ala Tyr Val Pro Arg His Glu Leu Cys Leu Ser Asp Pro Gly Leu Glu 
                325                 330                 335     


Pro Pro Val Tyr Val Pro Pro Pro Ser Tyr Arg Ser Pro Pro Gln Asn 
            340                 345                 350         


Ile Pro Asn Pro Tyr Leu Glu Asp Thr Val Pro Ile Asn Val Cys Gly 
        355                 360                 365             


Gly His Ser Gln Gln Gln Ser Pro Thr Glu Lys Ala Gly Ala Ser Gly 
    370                 375                 380                 


Gln Pro Pro Ser Gly Pro Pro Gly Thr Gly Asn Glu Tyr Gly Val Ser 
385                 390                 395                 400 


Pro Arg Leu Pro Gln Gly Leu Pro Ala His Pro Arg Pro Val Thr Ala 
                405                 410                 415     


Tyr Asp Gly Phe Val Gln Tyr Ile Pro Phe Asp Asp Pro Arg Leu Arg 
            420                 425                 430         


His Phe Lys Leu Ala Gln Pro Gln Gly Phe Cys Glu Asp Ile Lys Leu 
        435                 440                 445             


Asp Asp Lys Ser Tyr Asn Ser Ser Pro Val Thr Ala Gln Glu Pro Ala 
    450                 455                 460                 


His Gly Gly Met Gln Pro Asp Gly Ala Ile Trp Asn Pro Gln Ser Leu 
465                 470                 475                 480 


Ile Pro Pro Ser Gly Asp Glu Arg Gly Leu Val Leu Ala Asp Ser Ser 
                485                 490                 495     


Pro Arg Trp Leu Trp Gly Gln Pro Pro Gly Asp Gly Glu Asn Ser Gly 
            500                 505                 510         


Leu Pro Asn Gln Arg Asp Arg Cys Val Ala Arg Gly Gln Trp Pro Asp 
        515                 520                 525             


Val Arg Gly Ser Gln His Gly His Thr Gly Arg Gln Val Ser Ser Pro 
    530                 535                 540                 


Tyr Ser Gln Gly Glu Ser Thr Cys Glu Thr Gln Thr Lys Leu Lys Lys 
545                 550                 555                 560 


Phe Gln Thr Gly Thr Arg Thr Lys Lys Ser Ser Lys Lys Lys Met Asn 
                565                 570                 575     


Glu Thr Ile Phe Cys Leu Val Ser Ile Pro Val Lys Ser Glu Ser His 
            580                 585                 590         


Leu Pro Asp Arg Asp Met Asp Asn Asn Asp Leu Lys Pro Ser Ala Asp 
        595                 600                 605             


Gln Lys Asn Gly Ser Asp Lys Ser Pro Ala Leu Gln Glu Gln Ser Leu 
    610                 615                 620                 


Leu Ser Met Ser Ser Thr Asp Leu Glu Leu Gln Ala Leu Thr Gly Ser 
625                 630                 635                 640 


Met Gly Gly Arg Thr Glu Phe Gln Lys Gln Asp Leu Gly Glu Pro Glu 
                645                 650                 655     


Glu Asp Arg Gln Thr Asn Asp Leu Ser Phe Ile His Leu Thr Lys His 
            660                 665                 670         


Arg Glu Leu Lys His Ser Gly Ser Trp Pro Gly His Arg Tyr Arg Asp 
        675                 680                 685             


Gln Gln Thr Gln Thr Ser Phe Ser Glu Glu Pro Gln Ser Ser Gln Leu 
    690                 695                 700                 


Leu Pro Gly Ala Lys Leu Gly Gly Pro Ser Arg Ala Ala Leu Ser Pro 
705                 710                 715                 720 


Lys Cys Ser Asp Pro Ala Ala Ser Glu Ala Gln Thr His Thr Ala Phe 
                725                 730                 735     


Pro Thr Gly Asp His Lys Gln Arg Pro Ser Ala Arg Asn Leu Lys Gly 
            740                 745                 750         


His Arg Ser Leu Ser Pro Ser Ser Asn Ser Ala Phe Ser Arg Thr Ser 
        755                 760                 765             


Leu Ser Val Asp Gln Ala Pro Thr Pro Lys Ala Gly Arg Ser Gln Pro 
    770                 775                 780                 


Cys Val Asp Val His Gly Leu Gly Ala His Pro Gly Pro Lys Arg Glu 
785                 790                 795                 800 


Val Val Lys Gly Glu Pro Thr Gly Pro Cys Asn Ser Lys Gln Leu Phe 
                805                 810                 815     


Gly Gln Phe Leu Leu Lys Pro Val Ser Arg Arg Pro Trp Asp Leu Ile 
            820                 825                 830         


Ser Gln Leu Glu Ser Phe Asn Lys Glu Leu Gln Glu Glu Glu Glu Ser 
        835                 840                 845             


Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Glu Glu Ser Glu Ala 
    850                 855                 860                 


Glu Pro Gln Gln Glu Asn Arg Ala His Cys Arg Gln Glu Asp Val Gly 
865                 870                 875                 880 


Phe Arg Gly Asn Ser Pro Glu Met Arg Val Glu Pro Gln Pro Arg Met 
                885                 890                 895     


Trp Val Pro Glu Ser Pro Val Cys Arg Ser Gly Arg Gly Glu Ser Lys 
            900                 905                 910         


Ser Glu Ser Trp Ser Glu Glu Leu Gln Pro Gly His Pro Arg Ala Trp 
        915                 920                 925             


Pro Pro Ser Pro Gly Arg Phe Arg Val Glu Glu Gly Gly Gly Ala Pro 
    930                 935                 940                 


Phe Cys Ser Ala Asp Gly Ser Thr Ser Ala Glu Lys Arg His Leu Glu 
945                 950                 955                 960 


Val Ser Asn Gly Met Asp Glu Leu Ala Gly Ser Pro Phe Pro Val Thr 
                965                 970                 975     


Arg Met Ser Ser Arg Ser Ser Asp Ala Lys Pro Leu Pro Ala Ser Tyr 
            980                 985                 990         


Pro Ala Glu Pro Arg Glu Pro Gln  Glu Ser Pro Lys Ile  Thr Ser Ala 
        995                 1000                 1005             


Phe Ser  Ser Val Lys Pro Ser  Glu Ala Val Pro Arg  Lys Phe Asp 
    1010                 1015                 1020             


Ser Gly  Gly Glu Arg Gly Ala  Gly Leu Pro Leu Ser  Leu Ser Asn 
    1025                 1030                 1035             


Lys Asn  Arg Gly Leu Ser Ala  Pro Asp Leu Arg Ser  Val Gly Leu 
    1040                 1045                 1050             


Thr Pro  Gly Gln Glu Gln Gly  Ala Ser Glu Leu Glu  Gly Ser Leu 
    1055                 1060                 1065             


Gly Glu  Ala Ser Thr Ile Glu  Ile Pro Pro Gly Glu  Ser Leu Gln 
    1070                 1075                 1080             


Ala Arg  Ala Ala Arg Ile Leu  Gly Ile Glu Val Ala  Val Glu Ser 
    1085                 1090                 1095             


Leu Leu  Pro Gly Ile Arg Arg  Ala Gly Gln Asn Gln  Pro Ala Glu 
    1100                 1105                 1110             


Pro Asp  Ala Ser Ala Cys Thr  Pro Glu Ser Pro Gln  Glu Glu Leu 
    1115                 1120                 1125             


Leu Ser  Arg Pro Ala Pro Ala  Asp Val Pro Arg Val  Ser Thr Asp 
    1130                 1135                 1140             


Ala Phe  Tyr Gly Arg Arg Lys  Cys Gly Trp Thr Lys  Ser Pro Leu 
    1145                 1150                 1155             


Phe Val  Gly Asp Arg Asp Ser  Ala Arg Arg Ala Pro  Gln Ala Phe 
    1160                 1165                 1170             


Glu His  Ser Asp Val Asp Gly  Val Val Thr Ser Thr  Asp Pro Val 
    1175                 1180                 1185             


Pro Glu  Pro Glu Pro Ser Pro  Leu Glu Ser Lys Phe  Phe Glu Gln 
    1190                 1195                 1200             


Lys Asp  Val Glu Thr Lys Pro  Pro Phe Arg Ser Thr  Leu Phe His 
    1205                 1210                 1215             


Phe Val  Glu Arg Thr Pro Ser  Val Ala Gly Ser Glu  Lys Arg Leu 
    1220                 1225                 1230             


Arg Ser  Pro Ser Lys Val Ile  Glu Ser Leu Gln Glu  Lys Leu Ala 
    1235                 1240                 1245             


Ser Pro  Pro Arg Arg Ala Asp  Pro Asp Arg Leu Met  Arg Met Lys 
    1250                 1255                 1260             


Glu Val  Ser Ser Val Ser Arg  Met Arg Val Leu Ser  Phe Arg Asn 
    1265                 1270                 1275             


Ala Asp  Ser Gln Glu Asp Ala  Glu Glu Leu Lys Ala  Thr Thr Arg 
    1280                 1285                 1290             


Gly Gln  Ala Gly Leu Pro Gly  Gly Leu Val Ser Pro  Gly Ser Gly 
    1295                 1300                 1305             


Asp Arg  Ala Gln Arg Leu Gly  His Ser Leu Ser Val  Ser Lys Asp 
    1310                 1315                 1320             


Ser Ile  Ser Arg Glu Glu Lys  Glu His Pro Ala Ala  Gln Lys Glu 
    1325                 1330                 1335             


Lys Ser  Met Asp Gln Asp Phe  Trp Cys Pro Asp Ser  Tyr Asp Pro 
    1340                 1345                 1350             


Ser Arg  Val Glu Arg Val 
    1355                 


<210>  1095
<211>  584
<212>  PRT
<213>  Human

<400>  1095

Met Phe Ala Lys Ala Phe Arg Val Lys Ser Asn Thr Ala Ile Lys Gly 
1               5                   10                  15      


Ser Asp Arg Arg Lys Leu Arg Ala Asp Val Thr Thr Ala Phe Pro Thr 
            20                  25                  30          


Leu Gly Thr Asp Gln Val Ser Glu Leu Val Pro Gly Lys Glu Glu Leu 
        35                  40                  45              


Asn Ile Val Lys Leu Tyr Ala His Lys Gly Asp Ala Val Thr Val Tyr 
    50                  55                  60                  


Val Ser Gly Gly Asn Pro Ile Leu Phe Glu Leu Glu Lys Asn Leu Tyr 
65                  70                  75                  80  


Pro Thr Val Tyr Thr Leu Trp Ser Tyr Pro Asp Leu Leu Pro Thr Phe 
                85                  90                  95      


Thr Thr Trp Pro Leu Val Leu Glu Lys Leu Val Gly Gly Ala Asp Leu 
            100                 105                 110         


Met Leu Pro Gly Leu Val Met Pro Pro Ala Gly Leu Pro Gln Val Gln 
        115                 120                 125             


Lys Gly Asp Leu Cys Ala Ile Ser Leu Val Gly Asn Arg Ala Pro Val 
    130                 135                 140                 


Ala Ile Gly Val Ala Ala Met Ser Thr Ala Glu Met Leu Thr Ser Gly 
145                 150                 155                 160 


Leu Lys Gly Arg Gly Phe Ser Val Leu His Thr Tyr Gln Asp His Leu 
                165                 170                 175     


Trp Arg Ser Gly Asn Lys Ser Ser Pro Pro Ser Ile Ala Pro Leu Ala 
            180                 185                 190         


Leu Asp Ser Ala Asp Leu Ser Glu Glu Lys Gly Ser Val Gln Met Asp 
        195                 200                 205             


Ser Thr Leu Gln Gly Asp Met Arg His Met Thr Leu Glu Gly Glu Glu 
    210                 215                 220                 


Glu Asn Gly Glu Val His Gln Ala Arg Glu Asp Lys Ser Leu Ser Glu 
225                 230                 235                 240 


Ala Pro Glu Asp Thr Ser Thr Arg Gly Leu Asn Gln Asp Ser Thr Asp 
                245                 250                 255     


Ser Lys Thr Leu Gln Glu Gln Met Asp Glu Leu Leu Gln Gln Cys Phe 
            260                 265                 270         


Leu His Ala Leu Lys Cys Arg Val Lys Lys Ala Asp Leu Pro Leu Leu 
        275                 280                 285             


Thr Ser Thr Phe Leu Gly Ser His Met Phe Ser Cys Cys Pro Glu Gly 
    290                 295                 300                 


Arg Gln Leu Asp Ile Lys Lys Ser Ser Tyr Lys Lys Leu Ser Lys Phe 
305                 310                 315                 320 


Leu Gln Gln Met Gln Gln Glu Gln Ile Ile Gln Val Lys Glu Leu Ser 
                325                 330                 335     


Lys Gly Val Glu Ser Ile Val Ala Val Asp Trp Lys His Pro Arg Ile 
            340                 345                 350         


Thr Ser Phe Val Ile Pro Glu Pro Ser Pro Thr Ser Gln Thr Ile Gln 
        355                 360                 365             


Glu Gly Ser Arg Glu Gln Pro Tyr His Pro Pro Asp Ile Lys Pro Leu 
    370                 375                 380                 


Tyr Cys Val Pro Ala Ser Met Thr Leu Leu Phe Gln Glu Ser Gly His 
385                 390                 395                 400 


Lys Lys Gly Ser Phe Leu Glu Gly Ser Glu Val Arg Thr Ile Val Ile 
                405                 410                 415     


Asn Tyr Ala Lys Lys Asn Asp Leu Val Asp Ala Asp Asn Lys Asn Leu 
            420                 425                 430         


Val Arg Leu Asp Pro Ile Leu Cys Asp Cys Ile Leu Glu Lys Asn Glu 
        435                 440                 445             


Gln His Thr Val Met Lys Leu Pro Trp Asp Ser Leu Leu Thr Arg Cys 
    450                 455                 460                 


Leu Glu Lys Leu Gln Pro Ala Tyr Gln Val Thr Leu Pro Gly Gln Glu 
465                 470                 475                 480 


Pro Ile Val Lys Lys Gly Arg Ile Cys Pro Ile Asp Ile Thr Leu Ala 
                485                 490                 495     


Gln Arg Ala Ser Asn Lys Lys Val Thr Val Val Arg Asn Leu Glu Ala 
            500                 505                 510         


Tyr Gly Leu Asp Pro Tyr Ser Val Ala Ala Ile Leu Gln Gln Arg Cys 
        515                 520                 525             


Gln Ala Ser Thr Thr Val Asn Pro Ala Pro Gly Ala Lys Asp Ser Leu 
    530                 535                 540                 


Gln Val Gln Ile Gln Gly Asn Gln Val His His Leu Gly Trp Leu Leu 
545                 550                 555                 560 


Leu Glu Glu Tyr Gln Leu Pro Arg Lys His Ile Gln Gly Leu Glu Lys 
                565                 570                 575     


Ala Leu Lys Pro Gly Lys Lys Lys 
            580                 


<210>  1096
<211>  129
<212>  PRT
<213>  Human

<400>  1096

Met Ala Lys Ser Leu Arg Ser Lys Trp Lys Arg Lys Met Arg Ala Glu 
1               5                   10                  15      


Lys Arg Lys Lys Asn Ala Pro Lys Glu Ala Ser Arg Leu Lys Ser Ile 
            20                  25                  30          


Leu Lys Leu Asp Gly Asp Val Leu Met Lys Asp Val Gln Glu Ile Ala 
        35                  40                  45              


Thr Val Val Val Pro Lys Pro Lys His Cys Gln Glu Lys Met Gln Cys 
    50                  55                  60                  


Glu Val Lys Asp Glu Lys Asp Asp Met Lys Met Glu Thr Asp Ile Lys 
65                  70                  75                  80  


Arg Asn Lys Lys Thr Leu Leu Asp Gln His Gly Gln Tyr Pro Ile Trp 
                85                  90                  95      


Met Asn Gln Arg Gln Arg Lys Arg Leu Lys Ala Lys Arg Glu Lys Arg 
            100                 105                 110         


Lys Gly Lys Ser Lys Ala Lys Ala Val Lys Val Ala Lys Gly Leu Ala 
        115                 120                 125             


Trp 
    


<210>  1097
<211>  954
<212>  PRT
<213>  Human

<400>  1097

Met Leu Ser Asp Tyr Phe Leu Gly Leu Trp Ser Leu Ala Phe Arg Leu 
1               5                   10                  15      


Glu Glu Glu Gln Lys Met Arg Pro Glu Ile Ala Gly Leu Lys Pro Ala 
            20                  25                  30          


Asn Pro Pro Val Leu Pro Ala Pro Gln Lys Ala Asp Thr Asp Pro Glu 
        35                  40                  45              


Asn Leu Pro Glu Ile Ser Ser Gln Lys Thr Gln Arg His Ile Gln Arg 
    50                  55                  60                  


Gly Pro Pro His Leu Gln Ile Arg Pro Pro Ser Gln Asp Leu Lys Asp 
65                  70                  75                  80  


Gly Thr Gln Glu Glu Ala Thr Lys Arg Gln Glu Ala Pro Val Asp Pro 
                85                  90                  95      


Arg Pro Glu Gly Asp Pro Gln Arg Thr Val Ile Ser Trp Arg Gly Ala 
            100                 105                 110         


Val Ile Glu Pro Glu Gln Gly Thr Glu Leu Pro Ser Arg Arg Ala Glu 
        115                 120                 125             


Val Pro Thr Lys Pro Pro Leu Pro Pro Ala Arg Thr Gln Gly Thr Pro 
    130                 135                 140                 


Val His Leu Asn Tyr Arg Gln Lys Gly Val Ile Asp Val Phe Leu His 
145                 150                 155                 160 


Ala Trp Lys Gly Tyr Arg Lys Phe Ala Trp Gly His Asp Glu Leu Lys 
                165                 170                 175     


Pro Val Ser Arg Ser Phe Ser Glu Trp Phe Gly Leu Gly Leu Thr Leu 
            180                 185                 190         


Ile Asp Ala Leu Asp Thr Met Trp Ile Leu Gly Leu Arg Lys Glu Phe 
        195                 200                 205             


Glu Glu Ala Arg Lys Trp Val Ser Lys Lys Leu His Phe Glu Lys Asp 
    210                 215                 220                 


Val Asp Val Asn Leu Phe Glu Ser Thr Ile Arg Ile Leu Gly Gly Leu 
225                 230                 235                 240 


Leu Ser Ala Tyr His Leu Ser Gly Asp Ser Leu Phe Leu Arg Lys Ala 
                245                 250                 255     


Glu Asp Phe Gly Asn Arg Leu Met Pro Ala Phe Arg Thr Pro Ser Lys 
            260                 265                 270         


Ile Pro Tyr Ser Asp Val Asn Ile Gly Thr Gly Val Ala His Pro Pro 
        275                 280                 285             


Arg Trp Thr Ser Asp Ser Thr Val Ala Glu Val Thr Ser Ile Gln Leu 
    290                 295                 300                 


Glu Phe Arg Glu Leu Ser Arg Leu Thr Gly Asp Lys Lys Phe Gln Val 
305                 310                 315                 320 


Arg Gly Gln Ala Phe Trp Leu Asp Ala Pro Pro Leu Glu Leu Pro Phe 
                325                 330                 335     


Ala His His Ser Arg Tyr Cys Val Cys Val Cys Met Cys Met Cys Val 
            340                 345                 350         


Phe Arg Phe Phe Thr Val Ile Lys His Thr Lys Arg Thr Thr Leu Thr 
        355                 360                 365             


Ile Ser Arg Arg Gly Arg Trp Cys Tyr Ile His Ala Val Ala Gly Val 
    370                 375                 380                 


Gln Val Gly Gly Val Thr His Ile His Thr Val Ala Gly Val Gln Val 
385                 390                 395                 400 


Gly Gly Val Thr His Ile Trp Ala Val Ala Gly Val Gln Val Ser Gly 
                405                 410                 415     


Val Thr His Met Leu Leu Gln Glu Tyr Arg Ser Val Val Leu His Thr 
            420                 425                 430         


Phe Met Leu Leu Gln Ala Cys Arg Leu Val Leu Leu His Thr Cys Cys 
        435                 440                 445             


Cys Arg Ser Thr Gly Arg Trp Cys Tyr Met Leu Leu Gln Ala Cys Arg 
    450                 455                 460                 


Ser Val Val Leu His Ser Arg Cys Cys Arg Arg Ala Gly Arg Cys Cys 
465                 470                 475                 480 


Tyr Thr His Ser Cys Cys Cys Arg Ser Thr Gly Arg Trp Cys Tyr Thr 
                485                 490                 495     


Cys Cys Cys Arg Cys Ala Gly Arg Trp Trp Tyr Thr His Ser Cys Cys 
            500                 505                 510         


Cys Arg Ser Ile Gly Arg Trp Cys Tyr Thr His Ser Arg Cys Cys Arg 
        515                 520                 525             


Arg Ala Gly Arg Cys Cys Tyr Thr His Ser Cys Cys Cys Arg Ser Thr 
    530                 535                 540                 


Gly Arg Trp Cys Tyr Met Leu Leu Gln Ala Cys Arg Ser Val Val Thr 
545                 550                 555                 560 


Phe Thr Leu Leu Gln Ala Cys Arg Leu Val Leu His Thr Phe Thr Val 
                565                 570                 575     


Ala Gly Val Gln Val Ser Gly Val Thr His Ser His Leu Gln Ala Cys 
            580                 585                 590         


Arg Ser Val Val Leu His Thr Cys Cys Cys Arg Arg Ala Gly Arg Trp 
        595                 600                 605             


Cys Tyr Thr His Ser Leu Leu Gln Ala Cys Arg Ser Val Val Leu His 
    610                 615                 620                 


Ile His Ala Val Ala Gly Val Gln Val Gly Gly Val Thr Phe Thr Leu 
625                 630                 635                 640 


Leu Gln Thr Cys Arg Ser Val Leu Leu His Thr Leu Leu Gln Ala Cys 
                645                 650                 655     


Arg Leu Val Val Leu His Ser His Cys Cys Arg Arg Ala Gly Arg Trp 
            660                 665                 670         


Cys Tyr Thr His Ser Phe Cys Cys Arg Arg Ala Gly Gln Cys Tyr Thr 
        675                 680                 685             


His Ser Arg Cys Cys Arg Arg Ala Gly Arg Trp Cys Tyr Thr His Ser 
    690                 695                 700                 


Arg Cys Cys Arg Cys Ala Gly Arg Cys Cys Tyr Ile His Ala Val Ala 
705                 710                 715                 720 


Ser Val Gln Val Gly Gly Val Thr Phe Thr Leu Leu Leu Ala Cys Arg 
                725                 730                 735     


Ser Val Val Leu His Thr Phe Thr Leu Leu Gln Thr Cys Arg Ser Val 
            740                 745                 750         


Leu Leu His Thr Phe Met Leu Leu Gln Ala Cys Arg Ser Val Val Leu 
        755                 760                 765             


His Ser His Leu Gln Ala Cys Arg Ser Val Val Leu His Thr Phe Met 
    770                 775                 780                 


Leu Leu Gln Ala Cys Arg Ser Val Val Leu His Thr Phe Thr Leu Leu 
785                 790                 795                 800 


Gln Ala Cys Arg Ser Val Val Leu His Ser Cys Cys Cys Arg Arg Ala 
                805                 810                 815     


Gly Gln Trp Cys Tyr Thr His Ser Arg Cys Cys Arg His Ala Gly Arg 
            820                 825                 830         


Trp Cys Tyr Thr His Ser Arg Phe Cys Arg Arg Ala Gly Arg Trp Ser 
        835                 840                 845             


Tyr Ile His Thr Val Ala Gly Val Gln Val Gly Gly Val Thr Phe Thr 
    850                 855                 860                 


Leu Leu Gln Ala Cys Arg Leu Val Leu His Thr Phe Thr Leu Ala Gly 
865                 870                 875                 880 


Val Gln Val Gly Gly Val Thr His Met Leu Leu Gln Ala Cys Arg Ser 
                885                 890                 895     


Val Val Leu His Ser His Cys Cys Arg Arg Ala Gly Arg Trp Tyr Thr 
            900                 905                 910         


His Ser His Cys Cys Arg Arg Ala Gly Arg Trp Cys Tyr Thr His Ser 
        915                 920                 925             


Trp Cys Cys Arg Arg Ala Gly Arg Cys Tyr Thr His Ala Val Ala Gly 
    930                 935                 940                 


Val Gln Val Gly Gly Thr Phe Met Leu Leu 
945                 950                 


<210>  1098
<211>  878
<212>  PRT
<213>  Human

<400>  1098

Met Asp Pro Thr Ala Gly Ser Lys Lys Glu Pro Gly Gly Gly Ala Ala 
1               5                   10                  15      


Thr Glu Glu Gly Val Asn Arg Ile Ala Val Pro Lys Pro Pro Ser Ile 
            20                  25                  30          


Glu Glu Phe Ser Ile Val Lys Pro Ile Ser Arg Gly Ala Phe Gly Lys 
        35                  40                  45              


Val Tyr Leu Gly Gln Lys Gly Gly Lys Leu Tyr Ala Val Lys Val Val 
    50                  55                  60                  


Lys Lys Ala Asp Met Ile Asn Lys Asn Met Thr His Gln Val Gln Ala 
65                  70                  75                  80  


Glu Arg Asp Ala Leu Ala Leu Ser Lys Ser Pro Phe Ile Val His Leu 
                85                  90                  95      


Tyr Tyr Ser Leu Gln Ser Ala Asn Asn Val Tyr Leu Val Met Glu Tyr 
            100                 105                 110         


Leu Ile Gly Gly Asp Val Lys Ser Leu Leu His Ile Tyr Gly Tyr Phe 
        115                 120                 125             


Asp Glu Glu Met Ala Val Lys Tyr Ile Ser Glu Val Ala Leu Ala Leu 
    130                 135                 140                 


Asp Tyr Leu His Arg His Gly Ile Ile His Arg Asp Leu Lys Pro Asp 
145                 150                 155                 160 


Asn Met Leu Ile Ser Asn Glu Gly His Ile Lys Leu Thr Asp Phe Gly 
                165                 170                 175     


Leu Ser Lys Val Thr Leu Asn Arg Asp Ile Asn Met Met Asp Ile Leu 
            180                 185                 190         


Thr Thr Pro Ser Met Ala Lys Pro Arg Gln Asp Tyr Ser Arg Thr Pro 
        195                 200                 205             


Gly Gln Val Leu Ser Leu Ile Ser Ser Leu Gly Phe Asn Thr Pro Ile 
    210                 215                 220                 


Ala Glu Lys Asn Gln Asp Pro Ala Asn Ile Leu Ser Ala Cys Leu Ser 
225                 230                 235                 240 


Glu Thr Ser Gln Leu Ser Gln Gly Leu Val Cys Pro Met Ser Val Asp 
                245                 250                 255     


Gln Lys Asp Thr Thr Pro Tyr Ser Ser Lys Leu Leu Lys Ser Cys Leu 
            260                 265                 270         


Glu Thr Val Ala Ser Asn Pro Gly Met Pro Val Lys Cys Leu Thr Ser 
        275                 280                 285             


Asn Leu Leu Gln Ser Arg Lys Arg Leu Ala Thr Ser Ser Ala Ser Ser 
    290                 295                 300                 


Gln Ser His Thr Phe Ile Ser Ser Val Glu Ser Glu Cys His Ser Ser 
305                 310                 315                 320 


Pro Lys Trp Glu Lys Asp Cys Gln Glu Ser Asp Glu Ala Leu Gly Pro 
                325                 330                 335     


Thr Met Met Ser Trp Asn Ala Val Glu Lys Leu Cys Ala Lys Ser Ala 
            340                 345                 350         


Asn Ala Ile Glu Thr Lys Gly Phe Asn Lys Lys Asp Leu Glu Leu Ala 
        355                 360                 365             


Leu Ser Pro Ile His Asn Ser Ser Ala Leu Pro Thr Thr Gly Arg Ser 
    370                 375                 380                 


Cys Val Asn Leu Ala Lys Lys Cys Phe Ser Gly Glu Val Ser Trp Glu 
385                 390                 395                 400 


Ala Val Glu Leu Asp Val Asn Asn Ile Asn Met Asp Thr Asp Thr Ser 
                405                 410                 415     


Gln Leu Gly Phe His Gln Ser Asn Gln Trp Ala Val Asp Ser Gly Gly 
            420                 425                 430         


Ile Ser Glu Glu His Leu Gly Lys Arg Ser Leu Lys Arg Asn Phe Glu 
        435                 440                 445             


Leu Val Asp Ser Ser Pro Cys Lys Lys Ile Ile Gln Asn Lys Lys Thr 
    450                 455                 460                 


Cys Val Glu Tyr Lys His Asn Glu Met Thr Asn Cys Tyr Thr Asn Gln 
465                 470                 475                 480 


Asn Thr Gly Leu Thr Val Glu Val Gln Asp Leu Lys Leu Ser Val His 
                485                 490                 495     


Lys Ser Gln Gln Asn Asp Cys Ala Asn Lys Glu Asn Ile Val Asn Ser 
            500                 505                 510         


Phe Thr Asp Lys Gln Gln Thr Pro Glu Lys Leu Pro Ile Pro Met Ile 
        515                 520                 525             


Ala Lys Asn Leu Met Cys Glu Leu Asp Glu Asp Cys Glu Lys Asn Ser 
    530                 535                 540                 


Lys Arg Asp Tyr Leu Ser Ser Ser Phe Leu Cys Ser Asp Asp Asp Arg 
545                 550                 555                 560 


Ala Ser Lys Asn Ile Ser Met Asn Ser Asp Ser Ser Phe Pro Gly Ile 
                565                 570                 575     


Ser Ile Met Glu Ser Pro Leu Glu Ser Gln Pro Leu Asp Ser Asp Arg 
            580                 585                 590         


Ser Ile Lys Glu Ser Ser Phe Glu Glu Ser Asn Ile Glu Asp Pro Leu 
        595                 600                 605             


Ile Val Thr Pro Asp Cys Gln Glu Lys Thr Ser Pro Lys Gly Val Glu 
    610                 615                 620                 


Asn Pro Ala Val Gln Glu Ser Asn Gln Lys Met Leu Gly Pro Pro Leu 
625                 630                 635                 640 


Glu Val Leu Lys Thr Leu Ala Ser Lys Arg Asn Ala Val Ala Phe Arg 
                645                 650                 655     


Ser Phe Asn Ser His Ile Asn Ala Ser Asn Asn Ser Glu Pro Ser Arg 
            660                 665                 670         


Met Asn Met Thr Ser Leu Asp Ala Met Asp Ile Ser Cys Ala Tyr Ser 
        675                 680                 685             


Gly Ser Tyr Pro Met Ala Ile Thr Pro Thr Gln Lys Arg Arg Ser Cys 
    690                 695                 700                 


Met Pro His Gln Thr Pro Asn Gln Ile Lys Ser Gly Thr Pro Tyr Arg 
705                 710                 715                 720 


Thr Pro Lys Ser Val Arg Arg Gly Val Ala Pro Val Asp Asp Gly Arg 
                725                 730                 735     


Ile Leu Gly Thr Pro Asp Tyr Leu Ala Pro Glu Leu Leu Leu Gly Arg 
            740                 745                 750         


Ala His Gly Pro Ala Val Asp Trp Trp Ala Leu Gly Val Cys Leu Phe 
        755                 760                 765             


Glu Phe Leu Thr Gly Ile Pro Pro Phe Asn Asp Glu Thr Pro Gln Gln 
    770                 775                 780                 


Val Phe Gln Asn Ile Leu Lys Arg Asp Ile Pro Trp Pro Glu Gly Glu 
785                 790                 795                 800 


Glu Lys Leu Ser Asp Asn Ala Gln Ser Ala Val Glu Ile Leu Leu Thr 
                805                 810                 815     


Ile Asp Asp Thr Lys Arg Ala Gly Met Lys Glu Leu Lys Arg His Pro 
            820                 825                 830         


Leu Phe Ser Asp Val Asp Trp Glu Asn Leu Gln His Gln Thr Met Pro 
        835                 840                 845             


Phe Ile Pro Gln Pro Asp Asp Glu Thr Asp Thr Ser Tyr Phe Glu Ala 
    850                 855                 860                 


Arg Asn Thr Ala Gln His Leu Thr Val Ser Gly Phe Ser Leu 
865                 870                 875             


<210>  1099
<211>  545
<212>  PRT
<213>  Human

<400>  1099

Met Ala Glu Ala Ser Ser Leu Gly Arg Gln Ser Pro Arg Val Val Ser 
1               5                   10                  15      


Cys Leu Glu His Ser Leu Cys Pro Gly Glu Pro Gly Leu Gln Thr Thr 
            20                  25                  30          


Ala Val Val Ser Met Gly Ser Gly Asp His Gln Phe Asn Leu Ala Glu 
        35                  40                  45              


Ile Leu Ser Gln Asn Tyr Ser Val Arg Gly Glu Cys Glu Glu Ala Ser 
    50                  55                  60                  


Arg Cys Pro Asp Lys Pro Lys Glu Glu Leu Glu Lys Asp Phe Ile Ser 
65                  70                  75                  80  


Gln Ser Asn Asp Met Pro Phe Asp Glu Leu Leu Ala Leu Tyr Gly Tyr 
                85                  90                  95      


Glu Ala Ser Asp Pro Ile Ser Asp Arg Glu Ser Glu Gly Gly Asp Val 
            100                 105                 110         


Ala Pro Asn Leu Pro Asp Met Thr Leu Asp Lys Glu Gln Ile Ala Lys 
        115                 120                 125             


Asp Leu Leu Ser Gly Glu Glu Glu Glu Glu Thr Gln Ser Ser Ala Asp 
    130                 135                 140                 


Asp Leu Thr Pro Ser Val Thr Ser His Glu Ala Ser Asp Leu Phe Pro 
145                 150                 155                 160 


Asn Arg Ser Gly Ser Arg Phe Leu Ala Asp Glu Asp Arg Glu Pro Gly 
                165                 170                 175     


Ser Ser Ala Ser Ser Asp Thr Glu Glu Asp Ser Leu Pro Ala Asn Lys 
            180                 185                 190         


Cys Lys Lys Glu Ile Met Val Gly Pro Gln Phe Gln Ala Asp Leu Ser 
        195                 200                 205             


Asn Leu His Leu Asn Arg His Cys Glu Lys Ile Tyr Glu Asn Glu Asp 
    210                 215                 220                 


Gln Leu Leu Trp Asp Pro Ser Val Leu Pro Glu Arg Glu Val Glu Glu 
225                 230                 235                 240 


Phe Leu Tyr Arg Ala Val Lys Arg Arg Trp His Glu Met Ala Gly Pro 
                245                 250                 255     


Gln Leu Pro Glu Gly Glu Ala Val Lys Asp Ser Glu Gln Ala Leu Tyr 
            260                 265                 270         


Glu Leu Val Lys Cys Asn Phe Asn Val Glu Glu Ala Leu Arg Arg Leu 
        275                 280                 285             


Arg Phe Asn Val Lys Val Ile Arg Asp Gly Leu Cys Ala Trp Ser Glu 
    290                 295                 300                 


Glu Glu Cys Arg Asn Phe Glu His Gly Phe Arg Val His Gly Lys Asn 
305                 310                 315                 320 


Phe His Leu Ile Gln Ala Asn Lys Val Arg Thr Arg Ser Val Gly Glu 
                325                 330                 335     


Cys Val Glu Tyr Tyr Tyr Leu Trp Lys Lys Ser Glu Arg Tyr Asp Tyr 
            340                 345                 350         


Phe Ala Gln Gln Thr Arg Leu Gly Arg Arg Lys Tyr Val Pro Ser Gly 
        355                 360                 365             


Thr Thr Asp Ala Asp Gln Asp Leu Asp Gly Ser Asp Pro Asp Gly Pro 
    370                 375                 380                 


Gly Arg Pro Arg Pro Glu Gln Asp Thr Leu Thr Gly Met Arg Thr Asp 
385                 390                 395                 400 


Pro Leu Ser Val Asp Gly Thr Ala Gly Gly Leu Asp Glu Pro Gly Val 
                405                 410                 415     


Ala Ser Asp Gly Leu Pro Ser Ser Glu Pro Gly Pro Cys Ser Phe Gln 
            420                 425                 430         


Gln Leu Asp Glu Ser Pro Ala Val Pro Leu Ser His Arg Pro Pro Ala 
        435                 440                 445             


Leu Ala Asp Pro Ala Ser Tyr Gln Pro Ala Val Thr Ala Pro Glu Pro 
    450                 455                 460                 


Asp Ala Ser Pro Arg Leu Ala Val Asp Phe Ala Leu Pro Lys Glu Leu 
465                 470                 475                 480 


Pro Leu Ile Ser Ser His Val Asp Leu Ser Gly Asp Pro Glu Glu Thr 
                485                 490                 495     


Val Ala Pro Ala Gln Val Ala Leu Ser Val Thr Glu Phe Gly Leu Ile 
            500                 505                 510         


Gly Ile Gly Asp Val Asn Pro Phe Leu Ala Ala His Pro Thr Cys Pro 
        515                 520                 525             


Ala Pro Gly Leu His Ser Glu Pro Leu Ser His Cys Asn Val Met Thr 
    530                 535                 540                 


Cys 
545 


<210>  1100
<211>  750
<212>  PRT
<213>  Human

<400>  1100

Met Leu Arg Ala Lys Asn Gln Leu Phe Leu Leu Ser Pro His Tyr Leu 
1               5                   10                  15      


Arg Gln Val Lys Glu Ser Ser Gly Ser Arg Leu Ile Gln Gln Arg Leu 
            20                  25                  30          


Leu His Gln Gln Gln Pro Leu His Pro Glu Trp Ala Ala Leu Ala Lys 
        35                  40                  45              


Lys Gln Leu Lys Gly Lys Asn Pro Glu Asp Leu Ile Trp His Thr Pro 
    50                  55                  60                  


Glu Gly Ile Ser Ile Lys Pro Leu Tyr Ser Lys Arg Asp Thr Met Asp 
65                  70                  75                  80  


Leu Pro Glu Glu Leu Pro Gly Val Lys Pro Phe Thr Arg Gly Pro Tyr 
                85                  90                  95      


Pro Thr Met Tyr Thr Phe Arg Pro Trp Thr Ile Arg Gln Tyr Ala Gly 
            100                 105                 110         


Phe Ser Thr Val Glu Glu Ser Asn Lys Phe Tyr Lys Asp Asn Ile Lys 
        115                 120                 125             


Ala Gly Gln Gln Gly Leu Ser Val Ala Phe Asp Leu Ala Thr His Arg 
    130                 135                 140                 


Gly Tyr Asp Ser Asp Asn Pro Arg Val Arg Gly Asp Val Gly Met Ala 
145                 150                 155                 160 


Gly Val Ala Ile Asp Thr Val Glu Asp Thr Lys Ile Leu Phe Asp Gly 
                165                 170                 175     


Ile Pro Leu Glu Lys Met Ser Val Ser Met Thr Met Asn Gly Ala Val 
            180                 185                 190         


Ile Pro Val Leu Ala Asn Phe Ile Val Thr Gly Glu Glu Gln Gly Val 
        195                 200                 205             


Pro Lys Glu Lys Leu Thr Gly Thr Ile Gln Asn Asp Ile Leu Lys Glu 
    210                 215                 220                 


Phe Met Val Arg Asn Thr Tyr Ile Phe Pro Pro Glu Pro Ser Met Lys 
225                 230                 235                 240 


Ile Ile Ala Asp Ile Phe Glu Tyr Thr Ala Lys His Met Pro Lys Phe 
                245                 250                 255     


Asn Ser Ile Ser Ile Ser Gly Tyr His Met Gln Glu Ala Gly Ala Asp 
            260                 265                 270         


Ala Ile Leu Glu Leu Ala Tyr Thr Leu Ala Asp Gly Leu Glu Tyr Ser 
        275                 280                 285             


Arg Thr Gly Leu Gln Ala Gly Leu Thr Ile Asp Glu Phe Ala Pro Arg 
    290                 295                 300                 


Leu Ser Phe Phe Trp Gly Ile Gly Met Asn Phe Tyr Met Glu Ile Ala 
305                 310                 315                 320 


Lys Met Arg Ala Gly Arg Arg Leu Trp Ala His Leu Ile Glu Lys Met 
                325                 330                 335     


Phe Gln Pro Lys Asn Ser Lys Ser Leu Leu Leu Arg Ala His Cys Gln 
            340                 345                 350         


Thr Ser Gly Trp Ser Leu Thr Glu Gln Asp Pro Tyr Asn Asn Ile Val 
        355                 360                 365             


Arg Thr Ala Ile Glu Ala Met Ala Ala Val Phe Gly Gly Thr Gln Ser 
    370                 375                 380                 


Leu His Thr Asn Ser Phe Asp Glu Ala Leu Gly Leu Pro Thr Val Lys 
385                 390                 395                 400 


Ser Ala Arg Ile Ala Arg Asn Thr Gln Ile Ile Ile Gln Glu Glu Ser 
                405                 410                 415     


Gly Ile Pro Lys Val Ala Asp Pro Trp Gly Gly Ser Tyr Met Met Glu 
            420                 425                 430         


Cys Leu Thr Asn Asp Val Tyr Asp Ala Ala Leu Lys Leu Ile Asn Glu 
        435                 440                 445             


Ile Glu Glu Met Gly Gly Met Ala Lys Ala Val Ala Glu Gly Ile Pro 
    450                 455                 460                 


Lys Leu Arg Ile Glu Glu Cys Ala Ala Arg Arg Gln Ala Arg Ile Asp 
465                 470                 475                 480 


Ser Gly Ser Glu Val Ile Val Gly Val Asn Lys Tyr Gln Leu Glu Lys 
                485                 490                 495     


Glu Asp Ala Val Glu Val Leu Ala Ile Asp Asn Thr Ser Val Arg Asn 
            500                 505                 510         


Arg Gln Ile Glu Lys Leu Lys Lys Ile Lys Ser Ser Arg Asp Gln Ala 
        515                 520                 525             


Leu Ala Glu Arg Cys Leu Ala Ala Leu Thr Glu Cys Ala Ala Ser Gly 
    530                 535                 540                 


Asp Gly Asn Ile Leu Ala Leu Ala Val Asp Ala Ser Arg Ala Arg Cys 
545                 550                 555                 560 


Thr Val Gly Glu Ile Thr Asp Ala Leu Lys Lys Val Phe Gly Glu His 
                565                 570                 575     


Lys Ala Asn Asp Arg Met Val Ser Gly Ala Tyr Arg Gln Glu Phe Gly 
            580                 585                 590         


Glu Ser Lys Glu Ile Thr Ser Ala Ile Lys Arg Val His Lys Phe Met 
        595                 600                 605             


Glu Arg Glu Gly Arg Arg Pro Arg Leu Leu Val Ala Lys Met Gly Gln 
    610                 615                 620                 


Asp Gly His Asp Arg Gly Ala Lys Val Ile Ala Thr Gly Phe Ala Asp 
625                 630                 635                 640 


Leu Gly Phe Asp Val Asp Ile Gly Pro Leu Phe Gln Thr Pro Arg Glu 
                645                 650                 655     


Val Ala Gln Gln Ala Val Asp Ala Asp Val His Ala Val Gly Ile Ser 
            660                 665                 670         


Thr Leu Ala Ala Gly His Lys Thr Leu Val Pro Glu Leu Ile Lys Glu 
        675                 680                 685             


Leu Asn Ser Leu Gly Arg Pro Asp Ile Leu Val Met Cys Gly Gly Val 
    690                 695                 700                 


Ile Pro Pro Gln Asp Tyr Glu Phe Leu Phe Glu Val Gly Val Ser Asn 
705                 710                 715                 720 


Val Phe Gly Pro Gly Thr Arg Ile Pro Lys Ala Ala Val Gln Val Leu 
                725                 730                 735     


Asp Asp Ile Glu Lys Cys Leu Glu Lys Lys Gln Gln Ser Val 
            740                 745                 750 


<210>  1101
<211>  2039
<212>  PRT
<213>  Human

<400>  1101

Met Phe Asn Leu Met Lys Lys Asp Lys Asp Lys Asp Gly Gly Arg Lys 
1               5                   10                  15      


Glu Lys Lys Glu Lys Lys Glu Lys Lys Glu Arg Met Ser Ala Ala Glu 
            20                  25                  30          


Leu Arg Ser Leu Glu Glu Met Ser Leu Arg Arg Gly Phe Phe Asn Leu 
        35                  40                  45              


Asn Arg Ser Ser Lys Arg Glu Ser Lys Thr Arg Leu Glu Ile Ser Asn 
    50                  55                  60                  


Pro Ile Pro Ile Lys Val Ala Ser Gly Ser Asp Leu His Leu Thr Asp 
65                  70                  75                  80  


Ile Asp Ser Asp Ser Asn Arg Gly Ser Val Ile Leu Asp Ser Gly His 
                85                  90                  95      


Leu Ser Thr Ala Ser Ser Ser Asp Asp Leu Lys Gly Glu Glu Gly Ser 
            100                 105                 110         


Phe Arg Gly Ser Val Leu Gln Arg Ala Ala Lys Phe Gly Ser Leu Ala 
        115                 120                 125             


Lys Gln Asn Ser Gln Met Ile Val Lys Arg Phe Ser Phe Ser Gln Arg 
    130                 135                 140                 


Ser Arg Asp Glu Ser Ala Ser Glu Thr Ser Thr Pro Ser Glu His Ser 
145                 150                 155                 160 


Ala Ala Pro Ser Pro Gln Val Glu Val Arg Thr Leu Glu Gly Gln Leu 
                165                 170                 175     


Val Gln His Pro Gly Pro Gly Ile Pro Arg Pro Gly His Arg Ser Arg 
            180                 185                 190         


Ala Pro Glu Leu Val Thr Lys Lys Phe Pro Val Asp Leu Arg Leu Pro 
        195                 200                 205             


Pro Val Val Pro Leu Pro Pro Pro Thr Leu Arg Glu Leu Glu Leu Gln 
    210                 215                 220                 


Arg Arg Pro Thr Gly Asp Phe Gly Phe Ser Leu Arg Arg Thr Thr Met 
225                 230                 235                 240 


Leu Asp Arg Gly Pro Glu Gly Gln Ala Cys Arg Arg Val Val His Phe 
                245                 250                 255     


Ala Glu Pro Gly Ala Gly Thr Lys Asp Leu Ala Leu Gly Leu Val Pro 
            260                 265                 270         


Gly Asp Arg Leu Val Glu Ile Asn Gly His Asn Val Glu Ser Lys Ser 
        275                 280                 285             


Arg Asp Glu Ile Val Glu Met Ile Arg Gln Ser Gly Asp Ser Val Arg 
    290                 295                 300                 


Leu Lys Val Gln Pro Ile Pro Glu Leu Ser Glu Leu Ser Arg Ser Trp 
305                 310                 315                 320 


Leu Arg Ser Gly Glu Gly Pro Arg Arg Glu Pro Ser Asp Ala Lys Thr 
                325                 330                 335     


Glu Glu Gln Ile Ala Ala Glu Glu Ala Trp Asn Glu Thr Glu Lys Val 
            340                 345                 350         


Trp Leu Val His Arg Asp Gly Phe Ser Leu Ala Ser Gln Leu Lys Ser 
        355                 360                 365             


Glu Glu Leu Asn Leu Pro Glu Gly Lys Val Arg Val Lys Leu Asp His 
    370                 375                 380                 


Asp Gly Ala Ile Leu Asp Val Asp Glu Asp Asp Val Glu Lys Ala Asn 
385                 390                 395                 400 


Ala Pro Ser Cys Asp Arg Leu Glu Asp Leu Ala Ser Leu Val Tyr Leu 
                405                 410                 415     


Asn Glu Ser Ser Val Leu His Thr Leu Arg Gln Arg Tyr Gly Ala Ser 
            420                 425                 430         


Leu Leu His Thr Tyr Ala Gly Pro Ser Leu Leu Val Leu Gly Pro Arg 
        435                 440                 445             


Gly Ala Pro Ala Val Tyr Ser Glu Lys Val Met His Met Phe Lys Gly 
    450                 455                 460                 


Cys Arg Arg Glu Asp Met Ala Pro His Ile Tyr Ala Val Ala Gln Thr 
465                 470                 475                 480 


Ala Tyr Arg Ala Met Leu Met Ser Arg Gln Asp Gln Ser Ile Ile Leu 
                485                 490                 495     


Leu Gly Ser Ser Gly Ser Gly Lys Thr Thr Ser Cys Gln His Leu Val 
            500                 505                 510         


Gln Tyr Leu Ala Thr Ile Ala Gly Ile Ser Gly Asn Lys Val Phe Ser 
        515                 520                 525             


Val Glu Lys Trp Gln Ala Leu Tyr Thr Leu Leu Glu Ala Phe Gly Asn 
    530                 535                 540                 


Ser Pro Thr Ile Ile Asn Gly Asn Ala Thr Arg Phe Ser Gln Ile Leu 
545                 550                 555                 560 


Ser Leu Asp Phe Asp Gln Ala Gly Gln Val Ala Ser Ala Ser Ile Gln 
                565                 570                 575     


Thr Met Leu Leu Glu Lys Leu Arg Val Ala Arg Arg Pro Ala Ser Glu 
            580                 585                 590         


Ala Thr Phe Asn Val Phe Tyr Tyr Leu Leu Ala Cys Gly Asp Gly Thr 
        595                 600                 605             


Leu Arg Thr Glu Leu His Leu Asn His Leu Ala Glu Asn Asn Val Phe 
    610                 615                 620                 


Gly Ile Val Pro Leu Ala Lys Pro Glu Glu Lys Gln Lys Ala Ala Gln 
625                 630                 635                 640 


Gln Phe Ser Lys Leu Gln Ala Ala Met Lys Val Leu Gly Ile Ser Pro 
                645                 650                 655     


Asp Glu Gln Lys Ala Cys Trp Phe Ile Leu Ala Ala Ile Tyr His Leu 
            660                 665                 670         


Gly Ala Ala Gly Ala Thr Lys Glu Ala Ala Glu Ala Gly Arg Lys Gln 
        675                 680                 685             


Phe Ala Arg His Glu Trp Ala Gln Lys Ala Ala Tyr Leu Leu Gly Cys 
    690                 695                 700                 


Ser Leu Glu Glu Leu Ser Ser Ala Ile Phe Lys His Gln His Lys Gly 
705                 710                 715                 720 


Gly Thr Leu Gln Arg Ser Thr Ser Phe Arg Gln Gly Pro Glu Glu Ser 
                725                 730                 735     


Gly Leu Gly Asp Gly Thr Gly Pro Lys Leu Ser Ala Leu Glu Cys Leu 
            740                 745                 750         


Glu Gly Met Ala Ala Gly Leu Tyr Ser Glu Leu Phe Thr Leu Leu Val 
        755                 760                 765             


Ser Leu Val Asn Arg Ala Leu Lys Ser Ser Gln His Ser Leu Cys Ser 
    770                 775                 780                 


Met Met Ile Val Asp Thr Pro Gly Phe Gln Asn Pro Glu Gln Gly Gly 
785                 790                 795                 800 


Ser Ala Arg Gly Ala Ser Phe Glu Glu Leu Cys His Asn Tyr Thr Gln 
                805                 810                 815     


Asp Arg Leu Gln Arg Leu Phe His Glu Arg Thr Phe Val Gln Glu Leu 
            820                 825                 830         


Glu Arg Tyr Lys Glu Glu Asn Ile Glu Leu Ala Phe Asp Asp Leu Glu 
        835                 840                 845             


Pro Pro Thr Asp Asp Ser Val Ala Ala Val Asp Gln Ala Ser His Gln 
    850                 855                 860                 


Ser Leu Val Arg Ser Leu Ala Arg Thr Asp Glu Ala Arg Gly Leu Leu 
865                 870                 875                 880 


Trp Leu Leu Glu Glu Glu Ala Leu Val Pro Gly Ala Ser Glu Asp Thr 
                885                 890                 895     


Leu Leu Glu Arg Leu Phe Ser Tyr Tyr Gly Pro Gln Glu Gly Asp Lys 
            900                 905                 910         


Lys Gly Gln Ser Pro Leu Leu His Ser Ser Lys Pro His His Phe Leu 
        915                 920                 925             


Leu Gly His Ser His Gly Thr Asn Trp Val Glu Tyr Asn Val Thr Gly 
    930                 935                 940                 


Trp Leu Asn Tyr Thr Lys Gln Asn Pro Ala Thr Gln Asn Ala Pro Arg 
945                 950                 955                 960 


Leu Leu Gln Asp Ser Gln Lys Lys Ile Ile Ser Asn Leu Phe Leu Gly 
                965                 970                 975     


Arg Ala Gly Ser Ala Thr Val Leu Ser Gly Ser Ile Ala Gly Leu Glu 
            980                 985                 990         


Gly Gly Ser Gln Leu Ala Leu Arg  Arg Ala Thr Ser Met  Arg Lys Thr 
        995                 1000                 1005             


Phe Thr  Thr Gly Met Ala Ala  Val Lys Lys Lys Ser  Leu Cys Ile 
    1010                 1015                 1020             


Gln Met  Lys Leu Gln Val Asp  Ala Leu Ile Asp Thr  Ile Lys Lys 
    1025                 1030                 1035             


Ser Lys  Leu His Phe Val His  Cys Phe Leu Pro Val  Ala Glu Gly 
    1040                 1045                 1050             


Trp Ala  Gly Glu Pro Arg Ser  Ala Ser Ser Arg Arg  Val Ser Ser 
    1055                 1060                 1065             


Ser Ser  Glu Leu Asp Leu Pro  Ser Gly Asp His Cys  Glu Ala Gly 
    1070                 1075                 1080             


Leu Leu  Gln Leu Asp Val Pro  Leu Leu Arg Thr Gln  Leu Arg Gly 
    1085                 1090                 1095             


Ser Arg  Leu Leu Asp Ala Met  Arg Met Tyr Arg Gln  Gly Tyr Pro 
    1100                 1105                 1110             


Asp His  Met Val Phe Ser Glu  Phe Arg Arg Arg Phe  Asp Val Leu 
    1115                 1120                 1125             


Ala Pro  His Leu Thr Lys Lys  His Gly Arg Asn Tyr  Ile Val Val 
    1130                 1135                 1140             


Asp Glu  Arg Arg Ala Val Glu  Glu Leu Leu Glu Cys  Leu Asp Leu 
    1145                 1150                 1155             


Glu Lys  Ser Ser Cys Cys Met  Gly Leu Ser Arg Val  Phe Phe Arg 
    1160                 1165                 1170             


Ala Gly  Thr Leu Ala Arg Leu  Glu Glu Gln Arg Asp  Glu Gln Thr 
    1175                 1180                 1185             


Ser Arg  Asn Leu Thr Leu Phe  Gln Ala Ala Cys Arg  Gly Tyr Leu 
    1190                 1195                 1200             


Ala Arg  Gln His Phe Lys Lys  Arg Lys Ile Gln Asp  Leu Ala Ile 
    1205                 1210                 1215             


Arg Cys  Val Gln Lys Asn Ile  Lys Lys Asn Lys Gly  Val Lys Asp 
    1220                 1225                 1230             


Trp Pro  Trp Trp Lys Leu Phe  Thr Thr Val Arg Pro  Leu Ile Glu 
    1235                 1240                 1245             


Val Gln  Leu Ser Glu Glu Gln  Ile Arg Asn Lys Asp  Glu Glu Ile 
    1250                 1255                 1260             


Gln Gln  Leu Arg Ser Lys Leu  Glu Lys Ala Glu Lys  Glu Arg Asn 
    1265                 1270                 1275             


Glu Leu  Arg Leu Asn Ser Asp  Arg Leu Glu Ser Arg  Ile Ser Glu 
    1280                 1285                 1290             


Leu Thr  Ser Glu Leu Thr Asp  Glu Arg Asn Thr Gly  Glu Ser Ala 
    1295                 1300                 1305             


Ser Gln  Leu Leu Asp Ala Glu  Thr Ala Glu Arg Leu  Arg Ala Glu 
    1310                 1315                 1320             


Lys Glu  Met Lys Glu Leu Gln  Thr Gln Tyr Asp Ala  Leu Lys Lys 
    1325                 1330                 1335             


Gln Met  Glu Val Met Glu Met  Glu Val Met Glu Ala  Arg Leu Ile 
    1340                 1345                 1350             


Arg Ala  Ala Glu Ile Asn Gly  Glu Val Asp Asp Asp  Asp Ala Gly 
    1355                 1360                 1365             


Gly Glu  Trp Arg Leu Lys Tyr  Glu Arg Ala Val Arg  Glu Val Asp 
    1370                 1375                 1380             


Phe Thr  Lys Lys Arg Leu Gln  Gln Glu Phe Glu Asp  Lys Leu Glu 
    1385                 1390                 1395             


Val Glu  Gln Gln Asn Lys Arg  Gln Leu Glu Arg Arg  Leu Gly Asp 
    1400                 1405                 1410             


Leu Gln  Ala Asp Ser Glu Glu  Ser Gln Arg Ala Leu  Gln Gln Leu 
    1415                 1420                 1425             


Lys Lys  Lys Cys Gln Arg Leu  Thr Ala Glu Leu Gln  Asp Thr Lys 
    1430                 1435                 1440             


Leu His  Leu Glu Gly Gln Gln  Val Arg Asn His Glu  Leu Glu Lys 
    1445                 1450                 1455             


Lys Gln  Arg Arg Phe Asp Ser  Glu Leu Ser Gln Ala  His Glu Glu 
    1460                 1465                 1470             


Ala Gln  Arg Glu Lys Leu Gln  Arg Glu Lys Leu Gln  Arg Glu Lys 
    1475                 1480                 1485             


Asp Met  Leu Leu Ala Glu Ala  Phe Ser Leu Lys Gln  Gln Leu Glu 
    1490                 1495                 1500             


Glu Lys  Asp Met Asp Ile Ala  Gly Phe Thr Gln Lys  Val Val Ser 
    1505                 1510                 1515             


Leu Glu  Ala Glu Leu Gln Asp  Ile Ser Ser Gln Glu  Ser Lys Asp 
    1520                 1525                 1530             


Glu Ala  Ser Leu Ala Lys Val  Lys Lys Gln Leu Arg  Asp Leu Glu 
    1535                 1540                 1545             


Ala Lys  Val Lys Asp Gln Glu  Glu Glu Leu Asp Glu  Gln Ala Gly 
    1550                 1555                 1560             


Thr Ile  Gln Met Leu Glu Gln  Ala Lys Leu Arg Leu  Glu Met Glu 
    1565                 1570                 1575             


Met Glu  Arg Met Arg Gln Thr  His Ser Lys Glu Met  Glu Ser Arg 
    1580                 1585                 1590             


Asp Glu  Glu Val Glu Glu Ala  Arg Gln Ser Cys Gln  Lys Lys Leu 
    1595                 1600                 1605             


Lys Gln  Met Glu Val Gln Leu  Glu Glu Glu Tyr Glu  Asp Lys Gln 
    1610                 1615                 1620             


Lys Val  Leu Arg Glu Lys Arg  Glu Leu Glu Gly Lys  Leu Ala Thr 
    1625                 1630                 1635             


Leu Ser  Asp Gln Val Asn Arg  Arg Asp Phe Glu Ser  Glu Lys Arg 
    1640                 1645                 1650             


Leu Arg  Lys Asp Leu Lys Arg  Thr Lys Ala Leu Leu  Ala Asp Ala 
    1655                 1660                 1665             


Gln Leu  Met Leu Asp His Leu  Lys Asn Ser Ala Pro  Ser Lys Arg 
    1670                 1675                 1680             


Glu Ile  Ala Gln Leu Lys Asn  Gln Leu Glu Glu Ser  Glu Phe Thr 
    1685                 1690                 1695             


Cys Ala  Ala Ala Val Lys Ala  Arg Lys Ala Met Glu  Val Glu Ile 
    1700                 1705                 1710             


Glu Asp  Leu His Leu Gln Ile  Asp Asp Ile Ala Lys  Ala Lys Thr 
    1715                 1720                 1725             


Ala Leu  Glu Glu Gln Leu Ser  Arg Leu Gln Arg Glu  Lys Asn Glu 
    1730                 1735                 1740             


Ile Gln  Asn Arg Leu Glu Glu  Asp Gln Glu Asp Met  Asn Glu Leu 
    1745                 1750                 1755             


Met Lys  Lys His Lys Ala Ala  Val Ala Gln Ala Ser  Arg Asp Leu 
    1760                 1765                 1770             


Ala Gln  Ile Asn Asp Leu Gln  Ala Gln Leu Glu Glu  Ala Asn Lys 
    1775                 1780                 1785             


Glu Lys  Gln Glu Leu Gln Glu  Lys Leu Gln Ala Leu  Gln Ser Gln 
    1790                 1795                 1800             


Val Glu  Phe Leu Glu Gln Ser  Met Val Asp Lys Ser  Leu Val Ser 
    1805                 1810                 1815             


Arg Gln  Glu Ala Lys Ile Arg  Glu Leu Glu Thr Arg  Leu Glu Phe 
    1820                 1825                 1830             


Glu Arg  Thr Gln Val Lys Arg  Leu Glu Ser Leu Ala  Ser Arg Leu 
    1835                 1840                 1845             


Lys Glu  Asn Met Glu Lys Leu  Thr Glu Glu Arg Asp  Gln Arg Ile 
    1850                 1855                 1860             


Ala Ala  Glu Asn Arg Glu Lys  Glu Gln Asn Lys Arg  Leu Gln Arg 
    1865                 1870                 1875             


Gln Leu  Arg Asp Thr Lys Glu  Glu Met Gly Glu Leu  Ala Arg Lys 
    1880                 1885                 1890             


Glu Ala  Glu Ala Ser Arg Lys  Lys His Glu Leu Glu  Met Asp Leu 
    1895                 1900                 1905             


Glu Ser  Leu Glu Ala Ala Asn  Gln Ser Leu Gln Ala  Asp Leu Lys 
    1910                 1915                 1920             


Leu Ala  Phe Lys Arg Ile Gly  Asp Leu Gln Ala Ala  Ile Glu Asp 
    1925                 1930                 1935             


Glu Met  Glu Ser Asp Glu Asn  Glu Asp Leu Ile Asn  Ser Glu Gly 
    1940                 1945                 1950             


Asp Ser  Asp Val Asp Ser Glu  Leu Glu Asp Arg Val  Asp Gly Val 
    1955                 1960                 1965             


Lys Ser  Trp Leu Ser Lys Asn  Lys Gly Pro Ser Lys  Ala Ala Ser 
    1970                 1975                 1980             


Asp Asp  Gly Ser Leu Lys Ser  Ser Ser Pro Thr Ser  Tyr Trp Lys 
    1985                 1990                 1995             


Ser Leu  Ala Pro Asp Arg Ser  Asp Asp Glu His Asp  Pro Leu Asp 
    2000                 2005                 2010             


Asn Thr  Ser Arg Pro Arg Tyr  Ser His Ser Tyr Leu  Ser Asp Ser 
    2015                 2020                 2025             


Asp Thr  Glu Ala Lys Leu Thr  Glu Thr Asn Ala 
    2030                 2035                 


<210>  1102
<211>  445
<212>  PRT
<213>  Human

<400>  1102

Met Glu Phe Leu Gln Glu Leu Asn Ser Asp Val Ser Gly Ser Phe Val 
1               5                   10                  15      


Glu Glu Ser Pro Glu Asn Leu Leu Asp Asn Asp Pro Ser Phe Phe Cys 
            20                  25                  30          


Arg Phe Thr Val Val Val Ala Thr Gln Leu Pro Glu Ser Thr Ser Leu 
        35                  40                  45              


Arg Leu Ala Asp Val Leu Trp Asn Ser Gln Ile Pro Leu Leu Ile Cys 
    50                  55                  60                  


Arg Thr Tyr Gly Leu Val Gly Tyr Met Arg Ile Ile Ile Lys Glu His 
65                  70                  75                  80  


Pro Val Ile Glu Ser His Pro Asp Asn Ala Leu Glu Asp Leu Arg Leu 
                85                  90                  95      


Asp Lys Pro Phe Pro Glu Leu Arg Glu His Phe Gln Ser Tyr Asp Leu 
            100                 105                 110         


Asp His Met Glu Lys Lys Asp His Ser His Thr Pro Trp Ile Val Ile 
        115                 120                 125             


Ile Ala Lys Tyr Leu Ala Gln Trp Tyr Ser Glu Thr Asn Gly Arg Ile 
    130                 135                 140                 


Pro Lys Thr Tyr Lys Glu Lys Glu Asp Phe Arg Asp Leu Ile Arg Gln 
145                 150                 155                 160 


Gly Ile Leu Lys Asn Glu Asn Gly Ala Pro Glu Asp Glu Glu Asn Phe 
                165                 170                 175     


Glu Glu Ala Ile Lys Asn Val Asn Thr Ala Leu Asn Thr Thr Gln Ile 
            180                 185                 190         


Pro Ser Ser Ile Glu Asp Ile Phe Asn Asp Asp Arg Cys Ile Asn Ile 
        195                 200                 205             


Thr Lys Gln Thr Pro Ser Phe Trp Ile Leu Ala Arg Ala Leu Lys Glu 
    210                 215                 220                 


Phe Val Ala Lys Glu Gly Gln Gly Asn Leu Pro Val Arg Gly Thr Ile 
225                 230                 235                 240 


Pro Asp Met Ile Ala Asp Ser Gly Lys Tyr Ile Lys Leu Gln Asn Val 
                245                 250                 255     


Tyr Arg Glu Lys Ala Lys Lys Asp Ala Ala Ala Val Gly Asn His Val 
            260                 265                 270         


Ala Lys Leu Leu Gln Ser Ile Gly Gln Ala Pro Glu Ser Ile Ser Glu 
        275                 280                 285             


Lys Glu Leu Lys Leu Leu Cys Ser Asn Ser Ala Phe Leu Arg Val Val 
    290                 295                 300                 


Arg Cys Arg Ser Leu Ala Glu Glu Tyr Gly Leu Asp Thr Ile Asn Lys 
305                 310                 315                 320 


Asp Glu Ile Ile Ser Ser Met Asp Asn Pro Asp Asn Glu Ile Val Leu 
                325                 330                 335     


Tyr Leu Met Leu Arg Ala Val Asp Arg Phe His Lys Gln Gln Gly Arg 
            340                 345                 350         


Tyr Pro Gly Val Ser Asn Tyr Gln Val Glu Glu Asp Ile Gly Lys Leu 
        355                 360                 365             


Lys Ser Cys Leu Thr Gly Phe Leu Gln Glu Tyr Gly Leu Ser Val Met 
    370                 375                 380                 


Val Lys Asp Asp Tyr Val His Glu Phe Cys Arg Tyr Gly Ala Ala Glu 
385                 390                 395                 400 


Pro His Thr Ile Ala Ala Phe Leu Gly Gly Ala Ala Ala Gln Glu Val 
                405                 410                 415     


Ile Lys Ile Ile Thr Lys Gln Phe Val Ile Phe Asn Asn Thr Tyr Ile 
            420                 425                 430         


Tyr Ser Gly Met Ser Gln Thr Ser Ala Thr Phe Gln Leu 
        435                 440                 445 


<210>  1103
<211>  521
<212>  PRT
<213>  Human

<400>  1103

Met Ser Leu Ser Arg Ser Glu Glu Met His Arg Leu Thr Glu Asn Val 
1               5                   10                  15      


Tyr Lys Thr Ile Met Glu Gln Phe Asn Pro Ser Leu Arg Asn Phe Ile 
            20                  25                  30          


Ala Met Gly Lys Asn Tyr Glu Lys Ala Leu Ala Gly Val Thr Tyr Ala 
        35                  40                  45              


Ala Lys Gly Tyr Phe Asp Ala Leu Val Lys Met Gly Glu Leu Ala Ser 
    50                  55                  60                  


Glu Ser Gln Gly Ser Lys Glu Leu Gly Asp Val Leu Phe Gln Met Ala 
65                  70                  75                  80  


Glu Val His Arg Gln Ile Gln Asn Gln Leu Glu Glu Met Leu Lys Ser 
                85                  90                  95      


Phe His Asn Glu Leu Leu Thr Gln Leu Glu Gln Lys Val Glu Leu Asp 
            100                 105                 110         


Ser Arg Tyr Leu Ser Ala Ala Leu Lys Lys Tyr Gln Thr Glu Gln Arg 
        115                 120                 125             


Ser Lys Gly Asp Ala Leu Asp Lys Cys Gln Ala Glu Leu Lys Lys Leu 
    130                 135                 140                 


Arg Lys Lys Ser Gln Gly Ser Lys Asn Pro Gln Lys Tyr Ser Asp Lys 
145                 150                 155                 160 


Glu Leu Gln Tyr Ile Asp Ala Ile Ser Asn Lys Gln Gly Glu Leu Glu 
                165                 170                 175     


Asn Tyr Val Ser Asp Gly Tyr Lys Thr Ala Leu Thr Glu Glu Arg Arg 
            180                 185                 190         


Arg Phe Cys Phe Leu Val Glu Lys Gln Cys Ala Val Ala Lys Asn Ser 
        195                 200                 205             


Ala Ala Tyr His Ser Lys Gly Lys Glu Leu Leu Ala Gln Lys Leu Pro 
    210                 215                 220                 


Leu Trp Gln Gln Ala Cys Ala Asp Pro Ser Lys Ile Pro Glu Arg Ala 
225                 230                 235                 240 


Val Gln Leu Met Gln Gln Val Ala Ser Asn Gly Ala Thr Leu Pro Ser 
                245                 250                 255     


Ala Leu Ser Ala Ser Lys Ser Asn Leu Val Ile Ser Asp Pro Ile Pro 
            260                 265                 270         


Gly Ala Lys Pro Leu Pro Val Pro Pro Glu Leu Ala Pro Phe Val Gly 
        275                 280                 285             


Arg Met Ser Ala Gln Glu Ser Thr Pro Ile Met Asn Gly Val Thr Gly 
    290                 295                 300                 


Pro Asp Gly Glu Asp Tyr Ser Pro Trp Ala Asp Arg Lys Ala Ala Gln 
305                 310                 315                 320 


Pro Lys Ser Leu Ser Pro Pro Gln Ser Gln Ser Lys Leu Ser Asp Ser 
                325                 330                 335     


Tyr Ser Asn Thr Leu Pro Val Arg Lys Ser Val Thr Pro Lys Asn Ser 
            340                 345                 350         


Tyr Ala Thr Thr Glu Asn Lys Thr Leu Pro Arg Ser Ser Ser Met Ala 
        355                 360                 365             


Ala Gly Leu Glu Arg Asn Gly Arg Met Arg Val Lys Ala Ile Phe Ser 
    370                 375                 380                 


His Ala Ala Gly Asp Asn Ser Thr Leu Leu Ser Phe Lys Glu Gly Asp 
385                 390                 395                 400 


Leu Ile Thr Leu Leu Val Pro Glu Ala Arg Asp Gly Trp His Tyr Gly 
                405                 410                 415     


Glu Ser Glu Lys Thr Lys Met Arg Gly Trp Phe Pro Phe Ser Tyr Thr 
            420                 425                 430         


Arg Val Leu Asp Ser Asp Gly Ser Asp Arg Leu His Met Ser Leu Gln 
        435                 440                 445             


Gln Gly Lys Ser Ser Ser Thr Gly Asn Leu Leu Asp Lys Asp Asp Leu 
    450                 455                 460                 


Ala Ile Pro Pro Pro Asp Tyr Gly Ala Ala Ser Arg Ala Phe Pro Ala 
465                 470                 475                 480 


Gln Thr Ala Ser Gly Phe Lys Gln Arg Pro Tyr Ser Val Ala Val Pro 
                485                 490                 495     


Ala Phe Ser Gln Gly Leu Asp Asp Tyr Gly Ala Arg Ser Met Ser Ser 
            500                 505                 510         


Gly Ser Gly Thr Leu Val Ser Thr Val 
        515                 520     


<210>  1104
<211>  294
<212>  PRT
<213>  Human

<400>  1104

Met Glu Asp Ser Met Asp Met Asp Met Ser Pro Leu Arg Pro Gln Asn 
1               5                   10                  15      


Tyr Leu Phe Gly Cys Glu Leu Lys Ala Asp Lys Asp Tyr His Phe Lys 
            20                  25                  30          


Val Asp Asn Asp Glu Asn Glu His Gln Leu Ser Leu Arg Thr Val Ser 
        35                  40                  45              


Leu Gly Ala Gly Ala Lys Asp Glu Leu His Ile Val Glu Ala Glu Ala 
    50                  55                  60                  


Met Asn Tyr Glu Gly Ser Pro Ile Lys Val Thr Leu Ala Thr Leu Lys 
65                  70                  75                  80  


Met Ser Val Gln Pro Thr Val Ser Leu Gly Gly Phe Glu Ile Thr Pro 
                85                  90                  95      


Pro Val Val Leu Arg Leu Lys Cys Gly Ser Gly Pro Val His Ile Ser 
            100                 105                 110         


Gly Gln His Leu Val Ala Val Glu Glu Asp Ala Glu Ser Glu Asp Glu 
        115                 120                 125             


Glu Glu Glu Asp Val Lys Leu Leu Ser Ile Ser Gly Lys Arg Ser Ala 
    130                 135                 140                 


Pro Gly Gly Gly Ser Lys Val Pro Gln Lys Lys Val Lys Leu Ala Ala 
145                 150                 155                 160 


Asp Glu Asp Asp Asp Asp Asp Asp Glu Glu Asp Asp Asp Glu Asp Asp 
                165                 170                 175     


Asp Asp Asp Asp Phe Asp Asp Glu Glu Ala Glu Glu Lys Ala Pro Val 
            180                 185                 190         


Lys Lys Ser Ile Arg Asp Thr Pro Ala Lys Asn Ala Gln Lys Ser Asn 
        195                 200                 205             


Gln Asn Gly Lys Asp Ser Lys Pro Ser Ser Thr Pro Arg Ser Lys Gly 
    210                 215                 220                 


Gln Glu Ser Phe Lys Lys Gln Glu Lys Thr Pro Lys Thr Pro Lys Gly 
225                 230                 235                 240 


Pro Ser Ser Val Glu Asp Ile Lys Ala Lys Met Gln Ala Ser Ile Glu 
                245                 250                 255     


Lys Gly Gly Ser Leu Pro Lys Val Glu Ala Lys Phe Ile Asn Tyr Val 
            260                 265                 270         


Lys Asn Cys Phe Arg Met Thr Asp Gln Glu Ala Ile Gln Asp Leu Trp 
        275                 280                 285             


Gln Trp Arg Lys Ser Leu 
    290                 


<210>  1105
<211>  254
<212>  PRT
<213>  Human

<400>  1105

Met Ala Ala Tyr Lys Leu Val Leu Ile Arg His Gly Glu Ser Ala Trp 
1               5                   10                  15      


Asn Leu Glu Asn Arg Phe Ser Gly Trp Tyr Asp Ala Asp Leu Ser Pro 
            20                  25                  30          


Ala Gly His Glu Glu Ala Lys Arg Gly Gly Gln Ala Leu Arg Asp Ala 
        35                  40                  45              


Gly Tyr Glu Phe Asp Ile Cys Phe Thr Ser Val Gln Lys Arg Ala Ile 
    50                  55                  60                  


Arg Thr Leu Trp Thr Val Leu Asp Ala Ile Asp Gln Met Trp Leu Pro 
65                  70                  75                  80  


Val Val Arg Thr Trp Arg Leu Asn Glu Arg His Tyr Gly Gly Leu Thr 
                85                  90                  95      


Gly Leu Asn Lys Ala Glu Thr Ala Ala Lys His Gly Glu Ala Gln Val 
            100                 105                 110         


Lys Ile Trp Arg Arg Ser Tyr Asp Val Pro Pro Pro Pro Met Glu Pro 
        115                 120                 125             


Asp His Pro Phe Tyr Ser Asn Ile Ser Lys Asp Arg Arg Tyr Ala Asp 
    130                 135                 140                 


Leu Thr Glu Asp Gln Leu Pro Ser Cys Glu Ser Leu Lys Asp Thr Ile 
145                 150                 155                 160 


Ala Arg Ala Leu Pro Phe Trp Asn Glu Glu Ile Val Pro Gln Ile Lys 
                165                 170                 175     


Glu Gly Lys Arg Val Leu Ile Ala Ala His Gly Asn Ser Leu Arg Gly 
            180                 185                 190         


Ile Val Lys His Leu Glu Gly Leu Ser Glu Glu Ala Ile Met Glu Leu 
        195                 200                 205             


Asn Leu Pro Thr Gly Ile Pro Ile Val Tyr Glu Leu Asp Lys Asn Leu 
    210                 215                 220                 


Lys Pro Ile Lys Pro Met Gln Phe Leu Gly Asp Glu Glu Thr Val Arg 
225                 230                 235                 240 


Lys Ala Met Glu Ala Val Ala Ala Gln Gly Lys Ala Lys Lys 
                245                 250                 


<210>  1106
<211>  311
<212>  PRT
<213>  Human

<400>  1106

Met Leu Thr Lys Pro Leu Gln Gly Pro Pro Ala Pro Pro Gly Thr Pro 
1               5                   10                  15      


Thr Pro Pro Pro Gly Gly Lys Asp Arg Glu Ala Phe Glu Ala Glu Tyr 
            20                  25                  30          


Arg Leu Gly Pro Leu Leu Gly Lys Gly Gly Phe Gly Thr Val Phe Ala 
        35                  40                  45              


Gly His Arg Leu Thr Asp Arg Leu Gln Val Ala Ile Lys Val Ile Pro 
    50                  55                  60                  


Arg Asn Arg Val Leu Gly Trp Ser Pro Leu Ser Asp Ser Val Thr Cys 
65                  70                  75                  80  


Pro Leu Glu Val Ala Leu Leu Trp Lys Val Gly Ala Gly Gly Gly His 
                85                  90                  95      


Pro Gly Val Ile Arg Leu Leu Asp Trp Phe Glu Thr Gln Glu Gly Phe 
            100                 105                 110         


Met Leu Val Leu Glu Arg Pro Leu Pro Ala Gln Asp Leu Phe Asp Tyr 
        115                 120                 125             


Ile Thr Glu Lys Gly Pro Leu Gly Glu Gly Pro Ser Arg Cys Phe Phe 
    130                 135                 140                 


Gly Gln Val Val Ala Ala Ile Gln His Cys His Ser Arg Gly Val Val 
145                 150                 155                 160 


His Arg Asp Ile Lys Asp Glu Asn Ile Leu Ile Asp Leu Arg Arg Gly 
                165                 170                 175     


Cys Ala Lys Leu Ile Asp Phe Gly Ser Gly Ala Leu Leu His Asp Glu 
            180                 185                 190         


Pro Tyr Thr Asp Phe Asp Gly Thr Arg Val Tyr Ser Pro Pro Glu Trp 
        195                 200                 205             


Ile Ser Arg His Gln Tyr His Ala Leu Pro Ala Thr Val Trp Ser Leu 
    210                 215                 220                 


Gly Ile Leu Leu Tyr Asp Met Val Cys Gly Asp Ile Pro Phe Glu Arg 
225                 230                 235                 240 


Asp Gln Glu Ile Leu Glu Ala Glu Leu His Phe Pro Ala His Val Ser 
                245                 250                 255     


Pro Asp Cys Cys Ala Leu Ile Arg Arg Cys Leu Ala Pro Lys Pro Ser 
            260                 265                 270         


Ser Arg Pro Ser Leu Glu Glu Ile Leu Leu Asp Pro Trp Met Gln Thr 
        275                 280                 285             


Pro Ala Glu Asp Val Pro Leu Asn Pro Ser Lys Gly Gly Pro Ala Pro 
    290                 295                 300                 


Leu Ala Trp Ser Leu Leu Pro 
305                 310     


<210>  1107
<211>  661
<212>  PRT
<213>  Human

<400>  1107

Met Glu Met Thr Glu Met Thr Gly Val Ser Leu Lys Arg Gly Ala Leu 
1               5                   10                  15      


Val Val Glu Asp Asn Asp Ser Gly Val Pro Val Glu Glu Thr Lys Lys 
            20                  25                  30          


Gln Lys Leu Ser Glu Cys Ser Leu Thr Lys Gly Gln Asp Gly Leu Gln 
        35                  40                  45              


Asn Asp Phe Leu Ser Ile Ser Glu Asp Val Pro Arg Pro Pro Asp Thr 
    50                  55                  60                  


Val Ser Thr Gly Lys Gly Gly Lys Asn Ser Glu Ala Gln Leu Glu Asp 
65                  70                  75                  80  


Glu Glu Glu Glu Glu Glu Asp Gly Leu Ser Glu Glu Cys Glu Glu Glu 
                85                  90                  95      


Glu Ser Glu Ser Phe Ala Asp Met Met Lys His Gly Leu Thr Glu Ala 
            100                 105                 110         


Asp Val Gly Ile Thr Lys Phe Val Ser Ser His Gln Gly Phe Ser Gly 
        115                 120                 125             


Ile Leu Lys Glu Arg Tyr Ser Asp Phe Val Val His Glu Ile Gly Lys 
    130                 135                 140                 


Asp Gly Arg Ile Ser His Leu Asn Asp Leu Ser Ile Pro Val Asp Glu 
145                 150                 155                 160 


Glu Asp Pro Ser Glu Asp Ile Phe Thr Val Leu Thr Ala Glu Glu Lys 
                165                 170                 175     


Gln Arg Leu Glu Glu Leu Gln Leu Phe Lys Asn Lys Glu Thr Ser Val 
            180                 185                 190         


Ala Ile Glu Val Ile Glu Asp Thr Lys Glu Lys Arg Thr Ile Ile His 
        195                 200                 205             


Gln Ala Ile Lys Ser Leu Phe Pro Gly Leu Glu Thr Lys Thr Glu Asp 
    210                 215                 220                 


Arg Glu Gly Lys Lys Tyr Ile Val Ala Tyr His Ala Ala Gly Lys Lys 
225                 230                 235                 240 


Ala Leu Ala Asn Pro Arg Lys His Ser Trp Pro Lys Ser Arg Gly Ser 
                245                 250                 255     


Tyr Cys His Phe Val Leu Tyr Lys Glu Asn Lys Asp Thr Met Asp Ala 
            260                 265                 270         


Ile Asn Val Leu Ser Lys Tyr Leu Arg Val Lys Pro Asn Ile Phe Ser 
        275                 280                 285             


Tyr Met Gly Thr Lys Asp Lys Arg Ala Ile Thr Val Gln Glu Ile Ala 
    290                 295                 300                 


Val Leu Lys Ile Thr Ala Gln Arg Leu Ala His Leu Asn Lys Cys Leu 
305                 310                 315                 320 


Met Asn Phe Lys Leu Gly Asn Phe Ser Tyr Gln Lys Asn Pro Leu Lys 
                325                 330                 335     


Leu Gly Glu Leu Gln Gly Asn His Phe Thr Val Val Leu Arg Asn Ile 
            340                 345                 350         


Thr Gly Thr Asp Asp Gln Val Gln Gln Ala Met Asn Ser Leu Lys Glu 
        355                 360                 365             


Ile Gly Phe Ile Asn Tyr Tyr Gly Met Gln Arg Phe Gly Thr Thr Ala 
    370                 375                 380                 


Val Pro Thr Tyr Gln Val Gly Arg Ala Ile Leu Gln Asn Ser Trp Thr 
385                 390                 395                 400 


Glu Val Met Asp Leu Ile Leu Lys Pro Arg Ser Gly Ala Glu Lys Gly 
                405                 410                 415     


Tyr Leu Val Lys Cys Arg Glu Glu Trp Ala Lys Thr Lys Asp Pro Thr 
            420                 425                 430         


Ala Ala Leu Arg Lys Leu Pro Val Lys Arg Cys Val Glu Gly Gln Leu 
        435                 440                 445             


Leu Arg Gly Leu Ser Lys Tyr Gly Met Lys Asn Ile Val Ser Ala Phe 
    450                 455                 460                 


Gly Ile Ile Pro Arg Asn Asn Arg Leu Met Tyr Ile His Ser Tyr Gln 
465                 470                 475                 480 


Ser Tyr Val Trp Asn Asn Met Val Ser Lys Arg Ile Glu Asp Tyr Gly 
                485                 490                 495     


Leu Lys Pro Val Pro Gly Asp Leu Val Leu Lys Gly Ala Thr Ala Thr 
            500                 505                 510         


Tyr Ile Glu Glu Asp Asp Val Asn Asn Tyr Ser Ile His Asp Val Val 
        515                 520                 525             


Met Pro Leu Pro Gly Phe Asp Val Ile Tyr Pro Lys His Lys Ile Gln 
    530                 535                 540                 


Glu Ala Tyr Arg Glu Met Leu Thr Ala Asp Asn Leu Asp Ile Asp Asn 
545                 550                 555                 560 


Met Arg His Lys Ile Arg Asp Tyr Ser Leu Ser Gly Ala Tyr Arg Lys 
                565                 570                 575     


Ile Ile Ile Arg Pro Gln Asn Val Ser Trp Glu Val Val Ala Tyr Asp 
            580                 585                 590         


Asp Pro Lys Ile Pro Leu Phe Asn Thr Asp Val Asp Asn Leu Glu Gly 
        595                 600                 605             


Lys Thr Pro Pro Val Phe Ala Ser Glu Gly Lys Tyr Arg Ala Leu Lys 
    610                 615                 620                 


Met Asp Phe Ser Leu Pro Pro Ser Thr Tyr Ala Thr Met Ala Ile Arg 
625                 630                 635                 640 


Glu Val Leu Lys Met Asp Thr Ser Ile Lys Asn Gln Thr Gln Leu Asn 
                645                 650                 655     


Thr Thr Trp Leu Arg 
            660     


<210>  1108
<211>  411
<212>  PRT
<213>  Human

<400>  1108

Met Ser Lys Arg Pro Ser Tyr Ala Pro Pro Pro Thr Pro Ala Pro Ala 
1               5                   10                  15      


Thr Gln Met Pro Ser Thr Pro Gly Phe Val Gly Tyr Asn Pro Tyr Ser 
            20                  25                  30          


His Leu Ala Tyr Asn Asn Tyr Arg Leu Gly Gly Asn Pro Gly Thr Asn 
        35                  40                  45              


Ser Arg Val Thr Ala Ser Ser Gly Ile Thr Ile Pro Lys Pro Pro Lys 
    50                  55                  60                  


Pro Pro Asp Lys Pro Leu Met Pro Tyr Met Arg Tyr Ser Arg Lys Val 
65                  70                  75                  80  


Trp Asp Gln Val Lys Ala Ser Asn Pro Asp Leu Lys Leu Trp Glu Ile 
                85                  90                  95      


Gly Lys Ile Ile Gly Gly Met Trp Arg Asp Leu Thr Asp Glu Glu Lys 
            100                 105                 110         


Gln Glu Tyr Leu Asn Glu Tyr Glu Ala Glu Lys Ile Glu Tyr Asn Glu 
        115                 120                 125             


Ser Met Lys Ala Tyr His Asn Ser Pro Ala Tyr Leu Ala Tyr Ile Asn 
    130                 135                 140                 


Ala Lys Ser Arg Ala Glu Ala Ala Leu Glu Glu Glu Ser Arg Gln Arg 
145                 150                 155                 160 


Gln Ser Arg Met Glu Lys Gly Glu Pro Tyr Met Ser Ile Gln Pro Ala 
                165                 170                 175     


Glu Asp Pro Asp Asp Tyr Asp Asp Gly Phe Ser Met Lys His Thr Ala 
            180                 185                 190         


Thr Ala Arg Phe Gln Arg Asn His Arg Leu Ile Ser Glu Ile Leu Ser 
        195                 200                 205             


Glu Ser Val Val Pro Asp Val Arg Ser Val Val Thr Thr Ala Arg Met 
    210                 215                 220                 


Gln Val Leu Lys Arg Gln Val Gln Ser Leu Met Val His Gln Arg Lys 
225                 230                 235                 240 


Leu Glu Ala Glu Leu Leu Gln Ile Glu Glu Arg His Gln Glu Lys Lys 
                245                 250                 255     


Arg Lys Phe Leu Glu Ser Thr Asp Ser Phe Asn Asn Glu Leu Lys Arg 
            260                 265                 270         


Leu Cys Gly Leu Lys Val Glu Val Asp Met Glu Lys Ile Ala Ala Glu 
        275                 280                 285             


Ile Ala Gln Ala Glu Glu Gln Ala Arg Lys Arg Gln Glu Glu Arg Glu 
    290                 295                 300                 


Lys Glu Ala Ala Glu Gln Ala Glu Arg Ser Gln Ser Ser Ile Val Pro 
305                 310                 315                 320 


Glu Glu Glu Gln Ala Ala Asn Lys Gly Glu Glu Lys Lys Asp Asp Glu 
                325                 330                 335     


Asn Ile Pro Met Glu Thr Glu Glu Thr His Leu Glu Glu Thr Thr Glu 
            340                 345                 350         


Ser Gln Gln Asn Gly Glu Glu Gly Thr Ser Thr Pro Glu Asp Lys Glu 
        355                 360                 365             


Ser Gly Gln Glu Gly Val Asp Ser Met Ala Glu Glu Gly Thr Ser Asp 
    370                 375                 380                 


Ser Asn Thr Gly Ser Glu Ser Asn Ser Ala Thr Val Glu Glu Pro Pro 
385                 390                 395                 400 


Thr Asp Pro Ile Pro Glu Asp Glu Lys Lys Glu 
                405                 410     


<210>  1109
<211>  361
<212>  PRT
<213>  Human

<400>  1109

Met Tyr Gly Lys Gly Lys Ser Asn Ser Ser Ala Val Pro Ser Asp Ser 
1               5                   10                  15      


Gln Ala Arg Glu Lys Leu Ala Leu Tyr Val Tyr Glu Tyr Leu Leu His 
            20                  25                  30          


Val Gly Ala Gln Lys Ser Ala Gln Thr Phe Leu Ser Glu Ile Arg Trp 
        35                  40                  45              


Glu Lys Asn Ile Thr Leu Gly Glu Pro Pro Gly Phe Leu His Ser Trp 
    50                  55                  60                  


Trp Cys Val Phe Trp Asp Leu Tyr Cys Ala Ala Pro Glu Arg Arg Glu 
65                  70                  75                  80  


Thr Cys Glu His Ser Ser Glu Ala Lys Ala Phe His Asp Tyr Ser Ala 
                85                  90                  95      


Ala Ala Ala Pro Ser Pro Val Leu Gly Asn Ile Pro Pro Gly Asp Gly 
            100                 105                 110         


Met Pro Val Gly Pro Val Pro Pro Gly Phe Phe Gln Pro Phe Met Ser 
        115                 120                 125             


Pro Arg Tyr Pro Gly Gly Pro Arg Pro Pro Leu Arg Ile Pro Asn Gln 
    130                 135                 140                 


Ala Leu Gly Gly Val Pro Gly Ser Gln Pro Leu Leu Pro Ser Gly Met 
145                 150                 155                 160 


Asp Pro Thr Arg Gln Gln Gly His Pro Asn Met Gly Gly Pro Met Gln 
                165                 170                 175     


Arg Met Thr Pro Pro Arg Gly Met Val Pro Leu Gly Pro Gln Asn Tyr 
            180                 185                 190         


Gly Gly Ala Met Arg Pro Pro Leu Asn Ala Leu Gly Gly Pro Gly Met 
        195                 200                 205             


Pro Gly Met Asn Met Gly Pro Gly Gly Gly Arg Pro Trp Pro Asn Pro 
    210                 215                 220                 


Thr Asn Ala Asn Ser Ile Pro Tyr Ser Ser Ala Ser Pro Gly Asn Tyr 
225                 230                 235                 240 


Val Gly Pro Pro Gly Gly Gly Gly Pro Pro Gly Thr Pro Ile Met Pro 
                245                 250                 255     


Ser Pro Ala Asp Ser Thr Asn Ser Gly Asp Asn Met Tyr Thr Leu Met 
            260                 265                 270         


Asn Ala Val Pro Pro Gly Pro Asn Arg Pro Asn Phe Pro Met Gly Pro 
        275                 280                 285             


Gly Ser Asp Gly Pro Met Gly Gly Leu Gly Gly Met Glu Ser His His 
    290                 295                 300                 


Met Asn Gly Ser Leu Gly Ser Gly Asp Met Asp Ser Ile Ser Lys Asn 
305                 310                 315                 320 


Ser Pro Asn Asn Met Ser Leu Ser Asn Gln Pro Gly Thr Pro Arg Asp 
                325                 330                 335     


Asp Gly Glu Met Gly Gly Asn Phe Leu Asn Pro Phe Gln Ser Glu Ser 
            340                 345                 350         


Tyr Ser Pro Ser Met Thr Met Ser Val 
        355                 360     


<210>  1110
<211>  2542
<212>  PRT
<213>  Human

<400>  1110

Met Val Ala Leu Ser Leu Lys Ile Cys Val Arg His Cys Asn Val Val 
1               5                   10                  15      


Lys Thr Met Gln Phe Glu Pro Ser Thr Ala Val Tyr Asp Ala Cys Arg 
            20                  25                  30          


Val Ile Arg Glu Arg Val Pro Glu Ala Gln Thr Gly Gln Ala Ser Asp 
        35                  40                  45              


Tyr Gly Leu Phe Leu Ser Asp Glu Asp Pro Arg Lys Gly Ile Trp Leu 
    50                  55                  60                  


Glu Ala Gly Arg Thr Leu Asp Tyr Tyr Met Leu Arg Asn Gly Asp Ile 
65                  70                  75                  80  


Leu Glu Tyr Lys Lys Lys Gln Arg Pro Gln Lys Ile Arg Met Leu Asp 
                85                  90                  95      


Gly Ser Val Lys Thr Val Met Val Asp Asp Ser Lys Thr Val Gly Glu 
            100                 105                 110         


Leu Leu Val Thr Ile Cys Ser Arg Ile Gly Ile Thr Asn Tyr Glu Glu 
        115                 120                 125             


Tyr Ser Leu Ile Gln Glu Thr Ile Glu Glu Lys Lys Glu Glu Gly Thr 
    130                 135                 140                 


Gly Thr Leu Lys Lys Asp Arg Thr Leu Leu Arg Asp Glu Arg Lys Met 
145                 150                 155                 160 


Glu Lys Leu Lys Ala Lys Leu His Thr Asp Asp Asp Leu Asn Trp Leu 
                165                 170                 175     


Asp His Ser Arg Thr Phe Arg Glu Gln Gly Val Asp Glu Asn Glu Thr 
            180                 185                 190         


Leu Leu Leu Arg Arg Lys Phe Phe Tyr Ser Asp Gln Asn Val Asp Ser 
        195                 200                 205             


Arg Asp Pro Val Gln Leu Asn Leu Leu Tyr Val Gln Ala Arg Asp Asp 
    210                 215                 220                 


Ile Leu Asn Gly Ser His Pro Val Ser Phe Glu Lys Ala Cys Glu Phe 
225                 230                 235                 240 


Gly Gly Phe Gln Ala Gln Ile Gln Phe Gly Pro His Val Glu His Lys 
                245                 250                 255     


His Lys Pro Gly Phe Leu Asp Leu Lys Glu Phe Leu Pro Lys Glu Tyr 
            260                 265                 270         


Ile Lys Gln Arg Gly Ala Glu Lys Arg Ile Phe Gln Glu His Lys Asn 
        275                 280                 285             


Cys Gly Glu Met Ser Glu Ile Glu Ala Lys Val Lys Tyr Val Lys Leu 
    290                 295                 300                 


Ala Arg Ser Leu Arg Thr Tyr Gly Val Ser Phe Phe Leu Val Lys Glu 
305                 310                 315                 320 


Lys Met Lys Gly Lys Asn Lys Leu Val Pro Arg Leu Leu Gly Ile Thr 
                325                 330                 335     


Lys Asp Ser Val Met Arg Val Asp Glu Lys Thr Lys Glu Val Leu Gln 
            340                 345                 350         


Glu Trp Pro Leu Thr Thr Val Lys Arg Trp Ala Ala Ser Pro Lys Ser 
        355                 360                 365             


Phe Thr Leu Asp Phe Gly Glu Tyr Gln Glu Ser Tyr Tyr Ser Val Gln 
    370                 375                 380                 


Thr Thr Glu Gly Glu Gln Ile Ser Gln Leu Ile Ala Gly Tyr Ile Asp 
385                 390                 395                 400 


Ile Ile Leu Lys Lys Lys Gln Ser Lys Asp Arg Phe Gly Leu Glu Gly 
                405                 410                 415     


Asp Glu Glu Ser Thr Met Leu Glu Glu Ser Val Ser Pro Lys Lys Ser 
            420                 425                 430         


Thr Ile Leu Gln Gln Gln Phe Asn Arg Thr Gly Lys Ala Glu His Gly 
        435                 440                 445             


Ser Val Ala Leu Pro Ala Val Met Arg Ser Gly Ser Ser Gly Pro Glu 
    450                 455                 460                 


Thr Phe Asn Val Gly Ser Met Pro Ser Pro Gln Gln Gln Val Met Val 
465                 470                 475                 480 


Gly Gln Met His Arg Gly His Met Pro Pro Leu Thr Ser Ala Gln Gln 
                485                 490                 495     


Ala Leu Met Gly Thr Ile Asn Thr Ser Met His Ala Val Gln Gln Ala 
            500                 505                 510         


Gln Asp Asp Leu Ser Glu Leu Asp Ser Leu Pro Pro Leu Gly Gln Asp 
        515                 520                 525             


Met Ala Ser Arg Val Trp Val Gln Asn Lys Val Asp Glu Ser Lys His 
    530                 535                 540                 


Glu Ile His Ser Gln Val Asp Ala Ile Thr Ala Gly Thr Ala Ser Val 
545                 550                 555                 560 


Val Asn Leu Thr Ala Gly Asp Pro Ala Asp Thr Asp Tyr Thr Ala Val 
                565                 570                 575     


Gly Cys Ala Ile Thr Thr Ile Ser Ser Asn Leu Thr Glu Met Ser Lys 
            580                 585                 590         


Gly Val Lys Leu Leu Ala Ala Leu Met Asp Asp Glu Val Gly Ser Gly 
        595                 600                 605             


Glu Asp Leu Leu Arg Ala Ala Arg Thr Leu Ala Gly Ala Val Ser Asp 
    610                 615                 620                 


Leu Leu Lys Ala Val Gln Pro Thr Ser Gly Glu Pro Arg Gln Thr Val 
625                 630                 635                 640 


Leu Thr Ala Ala Gly Ser Ile Gly Gln Ala Ser Gly Asp Leu Leu Arg 
                645                 650                 655     


Gln Ile Gly Glu Asn Glu Thr Asp Glu Arg Phe Gln Asp Val Leu Met 
            660                 665                 670         


Ser Leu Ala Lys Ala Val Ala Asn Ala Ala Ala Met Leu Val Leu Lys 
        675                 680                 685             


Ala Lys Asn Val Ala Gln Val Ala Glu Asp Thr Val Leu Gln Asn Arg 
    690                 695                 700                 


Val Ile Ala Ala Ala Thr Gln Cys Ala Leu Ser Thr Ser Gln Leu Val 
705                 710                 715                 720 


Ala Cys Ala Lys Val Val Ser Pro Thr Ile Ser Ser Pro Val Cys Gln 
                725                 730                 735     


Glu Gln Leu Ile Glu Ala Gly Lys Leu Val Asp Arg Ser Val Glu Asn 
            740                 745                 750         


Cys Val Arg Ala Cys Gln Ala Ala Thr Thr Asp Ser Glu Leu Leu Lys 
        755                 760                 765             


Gln Val Ser Ala Ala Ala Ser Val Val Ser Gln Ala Leu His Asp Leu 
    770                 775                 780                 


Leu Gln His Val Arg Gln Phe Ala Ser Arg Gly Glu Pro Ile Gly Arg 
785                 790                 795                 800 


Tyr Asp Gln Ala Thr Asp Thr Ile Met Cys Val Thr Glu Ser Ile Phe 
                805                 810                 815     


Ser Ser Met Gly Asp Ala Gly Glu Met Val Arg Gln Ala Arg Val Leu 
            820                 825                 830         


Ala Gln Ala Thr Ser Asp Leu Val Asn Ala Met Arg Ser Asp Ala Glu 
        835                 840                 845             


Ala Glu Ile Asp Met Glu Asn Ser Lys Lys Leu Leu Ala Ala Ala Lys 
    850                 855                 860                 


Leu Leu Ala Asp Ser Thr Ala Arg Met Val Glu Ala Ala Lys Gly Ala 
865                 870                 875                 880 


Ala Ala Asn Pro Glu Asn Glu Asp Gln Gln Gln Arg Leu Arg Glu Ala 
                885                 890                 895     


Ala Glu Gly Leu Arg Val Ala Thr Asn Ala Ala Ala Gln Asn Ala Ile 
            900                 905                 910         


Lys Lys Lys Ile Val Asn Arg Leu Glu Val Ala Ala Lys Gln Ala Ala 
        915                 920                 925             


Ala Ala Ala Thr Gln Thr Ile Ala Ala Ser Gln Asn Ala Ala Val Ser 
    930                 935                 940                 


Asn Lys Asn Pro Ala Ala Gln Gln Gln Leu Val Gln Ser Cys Lys Ala 
945                 950                 955                 960 


Val Ala Asp His Ile Pro Gln Leu Val Gln Gly Val Arg Gly Ser Gln 
                965                 970                 975     


Ala Gln Ala Glu Asp Leu Ser Ala Gln Leu Ala Leu Ile Ile Ser Ser 
            980                 985                 990         


Gln Asn Phe Leu Gln Pro Gly Ser  Lys Met Val Ser Ser  Ala Lys Ala 
        995                 1000                 1005             


Ala Val  Pro Thr Val Ser Asp  Gln Ala Ala Ala Met  Gln Leu Ser 
    1010                 1015                 1020             


Gln Cys  Ala Lys Asn Leu Ala  Thr Ser Leu Ala Glu  Leu Arg Thr 
    1025                 1030                 1035             


Ala Ser  Gln Lys Ala His Glu  Ala Cys Gly Pro Met  Glu Ile Asp 
    1040                 1045                 1050             


Ser Ala  Leu Asn Thr Val Gln  Thr Leu Lys Asn Glu  Leu Gln Asp 
    1055                 1060                 1065             


Ala Lys  Met Ala Ala Val Glu  Ser Gln Leu Lys Pro  Leu Pro Gly 
    1070                 1075                 1080             


Glu Thr  Leu Glu Lys Cys Ala  Gln Asp Leu Gly Ser  Thr Ser Lys 
    1085                 1090                 1095             


Ala Val  Gly Ser Ser Met Ala  Gln Leu Leu Thr Cys  Ala Ala Gln 
    1100                 1105                 1110             


Gly Asn  Glu His Tyr Thr Gly  Val Ala Ala Arg Glu  Thr Ala Gln 
    1115                 1120                 1125             


Ala Leu  Lys Thr Leu Ala Gln  Ala Ala Arg Gly Val  Ala Ala Ser 
    1130                 1135                 1140             


Thr Thr  Asp Pro Ala Ala Ala  His Ala Met Leu Asp  Ser Ala Arg 
    1145                 1150                 1155             


Asp Val  Met Glu Gly Ser Ala  Met Leu Ile Gln Glu  Ala Lys Gln 
    1160                 1165                 1170             


Ala Leu  Ile Ala Pro Gly Asp  Ala Glu Arg Gln Gln  Arg Leu Ala 
    1175                 1180                 1185             


Gln Val  Ala Lys Ala Val Ser  His Ser Leu Asn Asn  Cys Val Asn 
    1190                 1195                 1200             


Cys Leu  Pro Gly Gln Lys Asp  Val Asp Val Ala Leu  Lys Ser Ile 
    1205                 1210                 1215             


Gly Glu  Ser Ser Lys Lys Leu  Leu Val Asp Ser Leu  Pro Pro Ser 
    1220                 1225                 1230             


Thr Lys  Pro Phe Gln Glu Ala  Gln Ser Glu Leu Asn  Gln Ala Ala 
    1235                 1240                 1245             


Ala Asp  Leu Asn Gln Ser Ala  Gly Glu Val Val His  Ala Thr Arg 
    1250                 1255                 1260             


Gly Gln  Ser Gly Glu Leu Ala  Ala Ala Ser Gly Lys  Phe Ser Asp 
    1265                 1270                 1275             


Asp Phe  Asp Glu Phe Leu Asp  Ala Gly Ile Glu Met  Ala Gly Gln 
    1280                 1285                 1290             


Ala Gln  Thr Lys Glu Asp Gln  Ile Gln Val Ile Gly  Asn Leu Lys 
    1295                 1300                 1305             


Asn Ile  Ser Met Ala Ser Ser  Lys Leu Leu Leu Ala  Ala Lys Ser 
    1310                 1315                 1320             


Leu Ser  Val Asp Pro Gly Ala  Pro Asn Ala Lys Asn  Leu Leu Ala 
    1325                 1330                 1335             


Ala Ala  Ala Arg Ala Val Thr  Glu Ser Ile Asn Gln  Leu Ile Thr 
    1340                 1345                 1350             


Leu Cys  Thr Gln Gln Ala Pro  Gly Gln Lys Glu Cys  Asp Asn Ala 
    1355                 1360                 1365             


Leu Arg  Glu Leu Glu Thr Val  Lys Gly Met Leu Asp  Asn Pro Asn 
    1370                 1375                 1380             


Glu Pro  Val Ser Asp Leu Ser  Tyr Phe Asp Cys Ile  Glu Ser Val 
    1385                 1390                 1395             


Met Glu  Asn Ser Lys Val Leu  Gly Glu Ser Met Ala  Gly Ile Ser 
    1400                 1405                 1410             


Gln Asn  Ala Lys Thr Gly Asp  Leu Pro Ala Phe Gly  Glu Cys Val 
    1415                 1420                 1425             


Gly Ile  Ala Ser Lys Ala Leu  Cys Gly Leu Thr Glu  Ala Ala Ala 
    1430                 1435                 1440             


Gln Ala  Ala Tyr Leu Val Gly  Ile Ser Asp Pro Asn  Ser Gln Ala 
    1445                 1450                 1455             


Gly His  Gln Gly Leu Val Asp  Pro Ile Gln Phe Ala  Arg Ala Asn 
    1460                 1465                 1470             


Gln Ala  Ile Gln Met Ala Cys  Gln Asn Leu Val Asp  Pro Gly Ser 
    1475                 1480                 1485             


Ser Pro  Ser Gln Val Leu Ser  Ala Ala Thr Ile Val  Ala Lys His 
    1490                 1495                 1500             


Thr Ser  Ala Leu Cys Asn Ala  Cys Arg Ile Ala Ser  Ser Lys Thr 
    1505                 1510                 1515             


Ala Asn  Pro Val Ala Lys Arg  His Phe Val Gln Ser  Ala Lys Glu 
    1520                 1525                 1530             


Val Ala  Asn Ser Thr Ala Asn  Leu Val Lys Thr Ile  Lys Ala Leu 
    1535                 1540                 1545             


Asp Gly  Asp Phe Ser Glu Asp  Asn Arg Asn Lys Cys  Arg Ile Ala 
    1550                 1555                 1560             


Thr Ala  Pro Leu Ile Glu Ala  Val Glu Asn Leu Thr  Ala Phe Ala 
    1565                 1570                 1575             


Ser Asn  Pro Glu Phe Val Ser  Ile Pro Ala Gln Ile  Ser Ser Glu 
    1580                 1585                 1590             


Gly Ser  Gln Ala Gln Glu Pro  Ile Leu Val Ser Ala  Lys Thr Met 
    1595                 1600                 1605             


Leu Glu  Ser Ser Ser Tyr Leu  Ile Arg Thr Ala Arg  Ser Leu Ala 
    1610                 1615                 1620             


Ile Asn  Pro Lys Asp Pro Pro  Thr Trp Ser Val Leu  Ala Gly His 
    1625                 1630                 1635             


Ser His  Thr Val Ser Asp Ser  Ile Lys Ser Leu Ile  Thr Ser Ile 
    1640                 1645                 1650             


Arg Asp  Lys Ala Pro Gly Gln  Arg Glu Cys Asp Tyr  Ser Ile Asp 
    1655                 1660                 1665             


Gly Ile  Asn Arg Cys Ile Arg  Asp Ile Glu Gln Ala  Ser Leu Ala 
    1670                 1675                 1680             


Ala Val  Ser Gln Ser Leu Ala  Thr Arg Asp Asp Ile  Ser Val Glu 
    1685                 1690                 1695             


Ala Leu  Gln Glu Gln Leu Thr  Ser Val Val Gln Glu  Ile Gly His 
    1700                 1705                 1710             


Leu Ile  Asp Pro Ile Ala Thr  Ala Ala Arg Gly Glu  Ala Ala Gln 
    1715                 1720                 1725             


Leu Gly  His Lys Val Thr Gln  Leu Ala Ser Tyr Phe  Glu Pro Leu 
    1730                 1735                 1740             


Ile Leu  Ala Ala Val Gly Val  Ala Ser Lys Ile Leu  Asp His Gln 
    1745                 1750                 1755             


Gln Gln  Met Thr Val Leu Asp  Gln Thr Lys Thr Leu  Ala Glu Ser 
    1760                 1765                 1770             


Ala Leu  Gln Met Leu Tyr Ala  Ala Lys Glu Gly Gly  Gly Asn Pro 
    1775                 1780                 1785             


Lys Ala  Gln His Thr His Asp  Ala Ile Thr Glu Ala  Ala Gln Leu 
    1790                 1795                 1800             


Met Lys  Glu Ala Val Asp Asp  Ile Met Val Thr Leu  Asn Glu Ala 
    1805                 1810                 1815             


Ala Ser  Glu Val Gly Leu Val  Gly Gly Met Val Asp  Ala Ile Ala 
    1820                 1825                 1830             


Glu Ala  Met Ser Lys Leu Asp  Glu Gly Thr Pro Pro  Glu Pro Lys 
    1835                 1840                 1845             


Gly Thr  Phe Val Asp Tyr Gln  Thr Thr Val Val Lys  Tyr Ser Lys 
    1850                 1855                 1860             


Ala Ile  Ala Val Thr Ala Gln  Glu Met Met Thr Lys  Ser Val Thr 
    1865                 1870                 1875             


Asn Pro  Glu Glu Leu Gly Gly  Leu Ala Ser Gln Met  Thr Ser Asp 
    1880                 1885                 1890             


Tyr Gly  His Leu Ala Phe Gln  Gly Gln Met Ala Ala  Ala Thr Ala 
    1895                 1900                 1905             


Glu Pro  Glu Glu Ile Gly Phe  Gln Ile Arg Thr Arg  Val Gln Asp 
    1910                 1915                 1920             


Leu Gly  His Gly Cys Ile Phe  Leu Val Gln Lys Ala  Gly Ala Leu 
    1925                 1930                 1935             


Gln Val  Cys Pro Thr Asp Ser  Tyr Thr Lys Arg Glu  Leu Ile Glu 
    1940                 1945                 1950             


Cys Ala  Arg Ala Val Thr Glu  Lys Val Ser Leu Val  Leu Ser Ala 
    1955                 1960                 1965             


Leu Gln  Ala Gly Asn Lys Gly  Thr Gln Ala Cys Ile  Thr Ala Ala 
    1970                 1975                 1980             


Thr Ala  Val Ser Gly Ile Ile  Ala Asp Leu Asp Thr  Thr Ile Met 
    1985                 1990                 1995             


Phe Ala  Thr Ala Gly Thr Leu  Asn Ala Glu Asn Ser  Glu Thr Phe 
    2000                 2005                 2010             


Ala Asp  His Arg Glu Asn Ile  Leu Lys Thr Ala Lys  Ala Leu Val 
    2015                 2020                 2025             


Glu Asp  Thr Lys Leu Leu Val  Ser Gly Ala Ala Ser  Thr Pro Asp 
    2030                 2035                 2040             


Lys Leu  Ala Gln Ala Ala Gln  Ser Ser Ala Ala Thr  Ile Thr Gln 
    2045                 2050                 2055             


Leu Ala  Glu Val Val Lys Leu  Gly Ala Ala Ser Leu  Gly Ser Asp 
    2060                 2065                 2070             


Asp Pro  Glu Thr Gln Val Val  Leu Ile Asn Ala Ile  Lys Asp Val 
    2075                 2080                 2085             


Ala Lys  Ala Leu Ser Asp Leu  Ile Ser Ala Thr Lys  Gly Ala Ala 
    2090                 2095                 2100             


Ser Lys  Pro Val Asp Asp Pro  Ser Met Tyr Gln Leu  Lys Gly Ala 
    2105                 2110                 2115             


Ala Lys  Val Met Val Thr Asn  Val Thr Ser Leu Leu  Lys Thr Val 
    2120                 2125                 2130             


Lys Ala  Val Glu Asp Glu Ala  Thr Arg Gly Thr Arg  Ala Leu Glu 
    2135                 2140                 2145             


Ala Thr  Ile Glu Cys Ile Lys  Gln Glu Leu Thr Val  Phe Gln Ser 
    2150                 2155                 2160             


Lys Asp  Val Pro Glu Lys Thr  Ser Ser Pro Glu Glu  Ser Ile Arg 
    2165                 2170                 2175             


Met Thr  Lys Gly Ile Thr Met  Ala Thr Ala Lys Ala  Val Ala Ala 
    2180                 2185                 2190             


Gly Asn  Ser Cys Arg Gln Glu  Asp Val Ile Ala Thr  Ala Asn Leu 
    2195                 2200                 2205             


Ser Arg  Lys Ala Val Ser Asp  Met Leu Thr Ala Cys  Lys Gln Ala 
    2210                 2215                 2220             


Ser Phe  His Pro Asp Val Ser  Asp Glu Val Arg Thr  Arg Ala Leu 
    2225                 2230                 2235             


Arg Phe  Gly Thr Glu Cys Thr  Leu Gly Tyr Leu Asp  Leu Leu Glu 
    2240                 2245                 2250             


His Val  Leu Val Ile Leu Gln  Lys Pro Thr Pro Glu  Phe Lys Gln 
    2255                 2260                 2265             


Gln Leu  Ala Ala Phe Ser Lys  Arg Val Ala Gly Ala  Val Thr Glu 
    2270                 2275                 2280             


Leu Ile  Gln Ala Ala Glu Ala  Met Lys Gly Thr Glu  Trp Val Asp 
    2285                 2290                 2295             


Pro Glu  Asp Pro Thr Val Ile  Ala Glu Thr Glu Leu  Leu Gly Ala 
    2300                 2305                 2310             


Ala Ala  Ser Ile Glu Ala Ala  Ala Lys Lys Leu Glu  Gln Leu Lys 
    2315                 2320                 2325             


Pro Arg  Ala Lys Pro Lys Gln  Ala Asp Glu Thr Leu  Asp Phe Glu 
    2330                 2335                 2340             


Glu Gln  Ile Leu Glu Ala Ala  Lys Ser Ile Ala Ala  Ala Thr Ser 
    2345                 2350                 2355             


Ala Leu  Val Lys Ser Ala Ser  Ala Ala Gln Arg Glu  Leu Val Ala 
    2360                 2365                 2370             


Gln Gly  Lys Val Gly Ser Ile  Pro Ala Asn Ala Ala  Asp Asp Gly 
    2375                 2380                 2385             


Gln Trp  Ser Gln Gly Leu Ile  Ser Ala Ala Arg Met  Val Ala Ala 
    2390                 2395                 2400             


Ala Thr  Ser Ser Leu Cys Glu  Ala Ala Asn Ala Ser  Val Gln Gly 
    2405                 2410                 2415             


His Ala  Ser Glu Glu Lys Leu  Ile Ser Ser Ala Lys  Gln Val Ala 
    2420                 2425                 2430             


Ala Ser  Thr Ala Gln Leu Leu  Val Ala Cys Lys Val  Lys Ala Asp 
    2435                 2440                 2445             


Gln Asp  Ser Glu Ala Met Arg  Arg Leu Gln Ala Ala  Gly Asn Ala 
    2450                 2455                 2460             


Val Lys  Arg Ala Ser Asp Asn  Leu Val Arg Ala Ala  Gln Lys Ala 
    2465                 2470                 2475             


Ala Phe  Gly Lys Ala Asp Asp  Asp Asp Val Val Val  Lys Thr Lys 
    2480                 2485                 2490             


Phe Val  Gly Gly Ile Ala Gln  Ile Ile Ala Ala Gln  Glu Glu Met 
    2495                 2500                 2505             


Leu Lys  Lys Glu Arg Glu Leu  Glu Glu Ala Arg Lys  Lys Leu Ala 
    2510                 2515                 2520             


Gln Ile  Arg Gln Gln Gln Tyr  Lys Phe Leu Pro Thr  Glu Leu Arg 
    2525                 2530                 2535             


Glu Asp  Glu Gly 
    2540         


<210>  1111
<211>  176
<212>  PRT
<213>  Human

<400>  1111

Met Ala Ala Ser Thr Asp Met Ala Gly Leu Glu Glu Ser Phe Arg Lys 
1               5                   10                  15      


Phe Ala Ile His Gly Asp Pro Lys Ala Ser Gly Gln Glu Met Asn Gly 
            20                  25                  30          


Lys Asn Trp Ala Lys Leu Cys Lys Asp Cys Lys Val Ala Asp Gly Lys 
        35                  40                  45              


Ser Val Thr Gly Thr Asp Val Asp Ile Val Phe Ser Lys Val Lys Gly 
    50                  55                  60                  


Lys Ser Ala Arg Val Ile Asn Tyr Glu Glu Phe Lys Lys Ala Leu Glu 
65                  70                  75                  80  


Glu Leu Ala Thr Lys Arg Phe Lys Gly Lys Ser Lys Glu Glu Ala Phe 
                85                  90                  95      


Asp Ala Ile Cys Gln Leu Val Ala Gly Lys Glu Pro Ala Asn Val Gly 
            100                 105                 110         


Val Thr Lys Ala Lys Thr Gly Gly Ala Val Asp Arg Leu Thr Asp Thr 
        115                 120                 125             


Ser Arg Tyr Thr Gly Ser His Lys Glu Arg Phe Asp Glu Ser Gly Lys 
    130                 135                 140                 


Gly Lys Gly Ile Ala Gly Arg Gln Asp Ile Leu Asp Asp Ser Gly Tyr 
145                 150                 155                 160 


Val Ser Ala Tyr Lys Asn Ala Gly Thr Tyr Asp Ala Lys Val Lys Lys 
                165                 170                 175     


<210>  1112
<211>  292
<212>  PRT
<213>  Human

<400>  1112

Met Gly Glu Lys Ser Glu Asn Cys Gly Val Pro Glu Asp Leu Leu Asn 
1               5                   10                  15      


Gly Leu Lys Val Thr Asp Thr Gln Glu Ala Glu Cys Ala Gly Pro Pro 
            20                  25                  30          


Val Pro Asp Pro Lys Asn Gln His Ser Gln Ser Lys Leu Leu Arg Asp 
        35                  40                  45              


Asp Glu Ala His Leu Gln Glu Asp Gln Gly Glu Glu Glu Cys Phe His 
    50                  55                  60                  


Asp Cys Ser Ala Ser Phe Glu Glu Glu Pro Gly Ala Asp Lys Val Glu 
65                  70                  75                  80  


Asn Lys Ser Asn Glu Asp Val Asn Ser Ser Glu Leu Asp Glu Glu Tyr 
                85                  90                  95      


Leu Ile Glu Leu Glu Lys Asn Met Ser Asp Glu Glu Lys Gln Lys Arg 
            100                 105                 110         


Arg Glu Glu Ser Thr Arg Leu Lys Glu Glu Gly Asn Glu Gln Phe Lys 
        115                 120                 125             


Lys Gly Asp Tyr Ile Glu Ala Glu Ser Ser Tyr Ser Arg Ala Leu Glu 
    130                 135                 140                 


Met Cys Pro Ser Cys Phe Gln Lys Glu Arg Ser Ile Leu Phe Ser Asn 
145                 150                 155                 160 


Arg Ala Ala Ala Arg Met Lys Gln Asp Lys Lys Glu Met Ala Ile Asn 
                165                 170                 175     


Asp Cys Ser Lys Ala Ile Gln Leu Asn Pro Ser Tyr Ile Arg Ala Ile 
            180                 185                 190         


Leu Arg Arg Ala Glu Leu Tyr Glu Lys Thr Asp Lys Leu Asp Glu Ala 
        195                 200                 205             


Leu Glu Asp Tyr Lys Ser Ile Leu Glu Lys Asp Pro Ser Ile His Gln 
    210                 215                 220                 


Ala Arg Glu Ala Cys Met Arg Leu Pro Lys Gln Ile Glu Glu Arg Asn 
225                 230                 235                 240 


Glu Arg Leu Lys Glu Glu Met Leu Gly Lys Leu Lys Asp Leu Gly Asn 
                245                 250                 255     


Leu Val Leu Arg Pro Phe Gly Leu Ser Thr Glu Asn Phe Gln Ile Lys 
            260                 265                 270         


Gln Asp Ser Ser Thr Gly Ser Tyr Ser Ile Asn Phe Val Gln Asn Pro 
        275                 280                 285             


Asn Asn Asn Arg 
    290         


<210>  1113
<211>  626
<212>  PRT
<213>  Human

<400>  1113

Met Ile Pro Ala Asn Ala Ser Ala Arg Lys Gly Pro Glu Gly Lys Tyr 
1               5                   10                  15      


Pro Leu His Tyr Leu Val Trp His Asn Arg His Arg Glu Leu Glu Lys 
            20                  25                  30          


Glu Val Arg Ala Gly Gln Val Asp Ile Glu Gln Leu Asp Pro Arg Gly 
        35                  40                  45              


Arg Thr Pro Leu His Leu Ala Thr Thr Leu Gly His Leu Glu Cys Ala 
    50                  55                  60                  


Arg Val Leu Leu Ala His Gly Ala Asp Val Gly Arg Glu Asn Arg Ser 
65                  70                  75                  80  


Gly Trp Thr Val Leu Gln Glu Ala Val Ser Thr Arg Asp Leu Glu Leu 
                85                  90                  95      


Val Gln Leu Val Leu Arg Tyr Arg Asp Tyr Gln Arg Val Val Lys Arg 
            100                 105                 110         


Leu Ala Gly Ile Pro Val Leu Leu Glu Lys Leu Arg Lys Ala Gln Asp 
        115                 120                 125             


Phe Tyr Val Glu Met Lys Trp Glu Phe Thr Ser Trp Val Pro Leu Val 
    130                 135                 140                 


Ser Lys Ile Cys Pro Ser Asp Thr Tyr Lys Val Trp Lys Ser Gly Gln 
145                 150                 155                 160 


Asn Leu Arg Val Asp Thr Thr Leu Leu Gly Phe Asp His Met Thr Trp 
                165                 170                 175     


Gln Arg Gly Asn Arg Ser Phe Val Phe Arg Gly Gln Asp Thr Ser Ala 
            180                 185                 190         


Val Val Met Glu Ile Asp His Asp Arg Arg Val Val Tyr Thr Glu Thr 
        195                 200                 205             


Leu Ala Leu Ala Gly Gln Asp Arg Glu Leu Leu Leu Ala Ala Ala Gln 
    210                 215                 220                 


Pro Thr Glu Glu Gln Val Leu Ser Arg Leu Thr Ala Pro Val Val Thr 
225                 230                 235                 240 


Thr Gln Leu Asp Thr Lys Asn Ile Ser Phe Glu Arg Asn Lys Thr Gly 
                245                 250                 255     


Ile Leu Gly Trp Arg Ser Glu Lys Thr Glu Met Val Asn Gly Tyr Glu 
            260                 265                 270         


Ala Lys Val Tyr Gly Ala Ser Asn Val Glu Leu Ile Thr Arg Thr Arg 
        275                 280                 285             


Thr Glu His Leu Ser Glu Gln His Lys Gly Lys Val Lys Gly Cys Lys 
    290                 295                 300                 


Thr Pro Leu Gln Ser Phe Leu Gly Ile Ala Glu Gln His Gly Gly Pro 
305                 310                 315                 320 


Gln Asn Gly Thr Leu Ile Thr Gln Thr Leu Ser Gln Ala Asn Pro Thr 
                325                 330                 335     


Ala Ile Thr Ala Glu Glu Tyr Phe Asn Pro Asn Phe Glu Leu Gly Asn 
            340                 345                 350         


Arg Asp Met Gly Arg Pro Met Glu Leu Thr Thr Lys Thr Gln Lys Phe 
        355                 360                 365             


Lys Ala Lys Leu Trp Leu Cys Glu Glu His Pro Leu Ser Leu Cys Glu 
    370                 375                 380                 


Gln Val Ala Pro Ile Ile Asp Leu Met Ala Val Ser Asn Ala Leu Phe 
385                 390                 395                 400 


Ala Lys Leu Arg Asp Phe Ile Thr Leu Arg Leu Pro Pro Gly Phe Pro 
                405                 410                 415     


Val Lys Ile Glu Ile Pro Ile Phe His Ile Leu Asn Ala Arg Ile Thr 
            420                 425                 430         


Phe Gly Asn Leu Asn Gly Cys Asp Glu Pro Val Pro Ser Val Arg Gly 
        435                 440                 445             


Ser Pro Ser Ser Glu Thr Pro Ser Pro Gly Ser Asp Ser Ser Ser Val 
    450                 455                 460                 


Ser Ser Ser Ser Ser Thr Thr Ser Cys Arg Gly Cys Glu Ile Ser Pro 
465                 470                 475                 480 


Ala Leu Phe Glu Ala Pro Arg Gly Tyr Ser Met Met Gly Gly Gln Arg 
                485                 490                 495     


Glu Ala Ala Thr Arg Asp Asp Asp Asp Asp Leu Leu Gln Phe Ala Ile 
            500                 505                 510         


Gln Gln Ser Leu Leu Glu Ala Gly Ser Glu Tyr Asp Gln Val Thr Ile 
        515                 520                 525             


Trp Glu Ala Leu Thr Asn Ser Lys Pro Gly Thr His Pro Met Ser Tyr 
    530                 535                 540                 


Glu Gly Arg Arg Gln Asp Arg Ser Ala Pro Pro Thr Pro Gln Arg Gln 
545                 550                 555                 560 


Pro Ala Pro Pro Ala Ser Val Pro Ser Pro Arg Pro Ser Ser Gly Pro 
                565                 570                 575     


Gly Ser Gly Gly His Val Phe Arg Ser Tyr Asp Glu Gln Leu Arg Leu 
            580                 585                 590         


Ala Met Glu Leu Ser Ala Gln Glu Gln Glu Glu Arg Arg Arg Arg Ala 
        595                 600                 605             


Arg Gln Glu Glu Glu Glu Leu Glu Arg Ile Leu Arg Leu Ser Leu Thr 
    610                 615                 620                 


Glu Gln 
625     


<210>  1114
<211>  955
<212>  PRT
<213>  Human

<400>  1114

Met Pro Ala Val Ser Lys Gly Asp Gly Met Arg Gly Leu Ala Val Phe 
1               5                   10                  15      


Ile Ser Asp Ile Arg Asn Cys Lys Ser Lys Glu Ala Glu Ile Lys Arg 
            20                  25                  30          


Ile Asn Lys Glu Leu Ala Asn Ile Arg Ser Lys Phe Lys Gly Asp Lys 
        35                  40                  45              


Ala Leu Asp Gly Tyr Ser Lys Lys Lys Tyr Val Cys Lys Leu Leu Phe 
    50                  55                  60                  


Ile Phe Leu Leu Gly His Asp Ile Asp Phe Gly His Met Glu Ala Val 
65                  70                  75                  80  


Asn Leu Leu Ser Ser Asn Lys Tyr Thr Glu Lys Gln Ile Gly Tyr Leu 
                85                  90                  95      


Phe Ile Ser Val Leu Val Asn Ser Asn Ser Glu Leu Ile Arg Leu Ile 
            100                 105                 110         


Asn Asn Ala Ile Lys Asn Asp Leu Ala Ser Arg Asn Pro Thr Phe Met 
        115                 120                 125             


Cys Leu Ala Leu His Cys Ile Ala Asn Val Gly Ser Arg Glu Met Gly 
    130                 135                 140                 


Glu Ala Phe Ala Ala Asp Ile Pro Arg Ile Leu Val Ala Gly Asp Ser 
145                 150                 155                 160 


Met Asp Ser Val Lys Gln Ser Ala Ala Leu Cys Leu Leu Arg Leu Tyr 
                165                 170                 175     


Lys Ala Ser Pro Asp Leu Val Pro Met Gly Glu Trp Thr Ala Arg Val 
            180                 185                 190         


Val His Leu Leu Asn Asp Gln His Met Gly Val Val Thr Ala Ala Val 
        195                 200                 205             


Ser Leu Ile Thr Cys Leu Cys Lys Lys Asn Pro Asp Asp Phe Lys Thr 
    210                 215                 220                 


Cys Val Ser Leu Ala Val Ser Arg Leu Ser Arg Ile Val Ser Ser Ala 
225                 230                 235                 240 


Ser Thr Asp Leu Gln Asp Tyr Thr Tyr Tyr Phe Val Pro Ala Pro Trp 
                245                 250                 255     


Leu Ser Val Lys Leu Leu Arg Leu Leu Gln Cys Tyr Pro Pro Pro Glu 
            260                 265                 270         


Asp Ala Ala Val Lys Gly Arg Leu Val Glu Cys Leu Glu Thr Val Leu 
        275                 280                 285             


Asn Lys Ala Gln Glu Pro Pro Lys Ser Lys Lys Val Gln His Ser Asn 
    290                 295                 300                 


Ala Lys Asn Ala Ile Leu Phe Glu Thr Ile Ser Leu Ile Ile His Tyr 
305                 310                 315                 320 


Asp Ser Glu Pro Asn Leu Leu Val Arg Ala Cys Asn Gln Leu Gly Gln 
                325                 330                 335     


Phe Leu Gln His Arg Glu Thr Asn Leu Arg Tyr Leu Ala Leu Glu Ser 
            340                 345                 350         


Met Cys Thr Leu Ala Ser Ser Glu Phe Ser His Glu Ala Val Lys Thr 
        355                 360                 365             


His Ile Asp Thr Val Ile Asn Ala Leu Lys Thr Glu Arg Asp Val Ser 
    370                 375                 380                 


Val Arg Gln Arg Ala Ala Asp Leu Leu Tyr Ala Met Cys Asp Arg Ser 
385                 390                 395                 400 


Asn Ala Lys Gln Ile Val Ser Glu Met Leu Arg Tyr Leu Glu Thr Ala 
                405                 410                 415     


Asp Tyr Ala Ile Arg Glu Glu Ile Val Leu Lys Val Ala Ile Leu Ala 
            420                 425                 430         


Glu Lys Tyr Ala Val Asp Tyr Ser Trp Tyr Val Asp Thr Ile Leu Asn 
        435                 440                 445             


Leu Ile Arg Ile Ala Gly Asp Tyr Val Ser Glu Glu Val Trp Tyr Arg 
    450                 455                 460                 


Val Leu Gln Ile Val Thr Asn Arg Asp Asp Val Gln Gly Tyr Ala Ala 
465                 470                 475                 480 


Lys Thr Val Phe Glu Ala Leu Gln Ala Pro Ala Cys His Glu Asn Met 
                485                 490                 495     


Val Lys Val Gly Gly Tyr Ile Leu Gly Glu Phe Gly Asn Leu Ile Ala 
            500                 505                 510         


Gly Asp Pro Arg Ser Ser Pro Pro Val Gln Phe Ser Leu Leu His Ser 
        515                 520                 525             


Lys Phe His Leu Cys Ser Val Ala Thr Arg Ala Leu Leu Leu Ser Thr 
    530                 535                 540                 


Tyr Ile Lys Phe Ile Asn Leu Phe Pro Glu Thr Lys Ala Thr Ile Gln 
545                 550                 555                 560 


Gly Val Leu Arg Ala Gly Ser Gln Leu Arg Asn Ala Asp Val Glu Leu 
                565                 570                 575     


Gln Gln Arg Ala Val Glu Tyr Leu Thr Leu Ser Ser Val Ala Ser Thr 
            580                 585                 590         


Asp Val Leu Ala Thr Val Leu Glu Glu Met Pro Pro Phe Pro Glu Arg 
        595                 600                 605             


Glu Ser Ser Ile Leu Ala Lys Leu Lys Arg Lys Lys Gly Pro Gly Ala 
    610                 615                 620                 


Gly Ser Ala Leu Asp Asp Gly Arg Arg Asp Pro Ser Ser Asn Asp Ile 
625                 630                 635                 640 


Asn Gly Gly Met Glu Pro Thr Pro Ser Thr Val Ser Thr Pro Ser Pro 
                645                 650                 655     


Ser Ala Asp Leu Leu Gly Leu Arg Ala Ala Pro Pro Pro Ala Ala Pro 
            660                 665                 670         


Pro Ala Ser Ala Gly Ala Gly Asn Leu Leu Val Asp Val Phe Asp Gly 
        675                 680                 685             


Pro Ala Ala Gln Pro Ser Leu Gly Pro Thr Pro Glu Glu Ala Phe Leu 
    690                 695                 700                 


Ser Pro Gly Pro Glu Asp Ile Gly Pro Pro Ile Pro Glu Ala Asp Glu 
705                 710                 715                 720 


Leu Leu Asn Lys Phe Val Cys Lys Asn Asn Gly Val Leu Phe Glu Asn 
                725                 730                 735     


Gln Leu Leu Gln Ile Gly Val Lys Ser Glu Phe Arg Gln Asn Leu Gly 
            740                 745                 750         


Arg Met Tyr Leu Phe Tyr Gly Asn Lys Thr Ser Val Gln Phe Gln Asn 
        755                 760                 765             


Phe Ser Pro Thr Val Val His Pro Gly Asp Leu Gln Thr Gln Leu Ala 
    770                 775                 780                 


Val Gln Thr Lys Arg Val Ala Ala Gln Val Asp Gly Gly Ala Gln Val 
785                 790                 795                 800 


Gln Gln Val Leu Asn Ile Glu Cys Leu Arg Asp Phe Leu Thr Pro Pro 
                805                 810                 815     


Leu Leu Ser Val Arg Phe Arg Tyr Gly Gly Ala Pro Gln Ala Leu Thr 
            820                 825                 830         


Leu Lys Leu Pro Val Thr Ile Asn Lys Phe Phe Gln Pro Thr Glu Met 
        835                 840                 845             


Ala Ala Gln Asp Phe Phe Gln Arg Trp Lys Gln Leu Ser Leu Pro Gln 
    850                 855                 860                 


Gln Glu Ala Gln Lys Ile Phe Lys Ala Asn His Pro Met Asp Ala Glu 
865                 870                 875                 880 


Val Thr Lys Ala Lys Leu Leu Gly Phe Gly Ser Ala Leu Leu Asp Asn 
                885                 890                 895     


Val Asp Pro Asn Pro Glu Asn Phe Val Gly Ala Gly Ile Ile Gln Thr 
            900                 905                 910         


Lys Ala Leu Gln Val Gly Cys Leu Leu Arg Leu Glu Pro Asn Ala Gln 
        915                 920                 925             


Ala Gln Met Tyr Arg Leu Thr Leu Arg Thr Ser Lys Glu Pro Val Ser 
    930                 935                 940                 


Arg His Leu Cys Glu Leu Leu Ala Gln Gln Phe 
945                 950                 955 


<210>  1115
<211>  243
<212>  PRT
<213>  Human

<400>  1115

Met Ser Arg Arg Lys Gln Gly Lys Pro Gln His Leu Ser Lys Arg Glu 
1               5                   10                  15      


Phe Ser Pro Glu Pro Leu Glu Ala Ile Leu Thr Asp Asp Glu Pro Asp 
            20                  25                  30          


His Gly Pro Leu Gly Ala Pro Glu Gly Asp His Asp Leu Leu Thr Cys 
        35                  40                  45              


Gly Gln Cys Gln Met Asn Phe Pro Leu Gly Asp Ile Leu Ile Phe Ile 
    50                  55                  60                  


Glu His Lys Arg Lys Gln Cys Asn Gly Ser Leu Cys Leu Glu Lys Ala 
65                  70                  75                  80  


Val Asp Lys Pro Pro Ser Pro Ser Pro Ile Glu Met Lys Lys Ala Ser 
                85                  90                  95      


Asn Pro Val Glu Val Gly Ile Gln Val Thr Pro Glu Asp Asp Asp Cys 
            100                 105                 110         


Leu Ser Thr Ser Ser Arg Gly Ile Cys Pro Lys Gln Glu His Ile Ala 
        115                 120                 125             


Asp Lys Leu Leu His Trp Arg Gly Leu Ser Ser Pro Arg Ser Ala His 
    130                 135                 140                 


Gly Ala Leu Ile Pro Thr Pro Gly Met Ser Ala Glu Tyr Ala Pro Gln 
145                 150                 155                 160 


Gly Ile Cys Lys Asp Glu Pro Ser Ser Tyr Thr Cys Thr Thr Cys Lys 
                165                 170                 175     


Gln Pro Phe Thr Ser Ala Trp Phe Leu Leu Gln His Ala Gln Asn Thr 
            180                 185                 190         


His Gly Leu Arg Ile Tyr Leu Glu Ser Glu His Gly Ser Pro Leu Thr 
        195                 200                 205             


Pro Arg Val Leu His Thr Pro Pro Phe Gly Val Val Pro Arg Glu Leu 
    210                 215                 220                 


Lys Met Cys Gly Ser Phe Arg Met Glu Ala Arg Glu Pro Leu Ser Ser 
225                 230                 235                 240 


Glu Lys Ile 
            


<210>  1116
<211>  659
<212>  PRT
<213>  Human

<400>  1116

Met Ser Leu Pro Pro Glu Lys Ala Ser Glu Leu Lys Gln Leu Ile His 
1               5                   10                  15      


Gln Gln Leu Ser Lys Met Asp Val His Gly Arg Ile Arg Glu Ile Leu 
            20                  25                  30          


Ala Glu Thr Ile Arg Glu Glu Leu Ala Pro Asp Gln Gln His Leu Ser 
        35                  40                  45              


Thr Glu Asp Leu Ile Lys Ala Leu Arg Arg Arg Gly Ile Ile Asp Asp 
    50                  55                  60                  


Val Met Lys Glu Leu Asn Phe Val Thr Asp Ser Val Glu Gln Glu Leu 
65                  70                  75                  80  


Pro Ser Ser Pro Lys Gln Pro Ile Cys Phe Asp Arg Gln Ser Thr Leu 
                85                  90                  95      


Lys Lys Thr Asn Ile Asp Pro Thr Arg Arg Tyr Leu Tyr Leu Gln Val 
            100                 105                 110         


Leu Gly Gly Lys Ala Phe Leu Glu His Leu Gln Glu Pro Glu Pro Leu 
        115                 120                 125             


Pro Gly Gln Val Cys Ser Thr Phe Thr Leu Cys Leu His Tyr Arg Asn 
    130                 135                 140                 


Gln Arg Phe Arg Ser Lys Pro Val Pro Cys Ala Cys Glu Pro Asp Phe 
145                 150                 155                 160 


His Asp Gly Phe Leu Leu Glu Val His Arg Glu Ser Leu Gly Asp Gly 
                165                 170                 175     


Thr Arg Met Ala Asp Ser Thr Thr Met Leu Ser Ile Ser Asp Pro Ile 
            180                 185                 190         


His Met Val Leu Ile Lys Thr Asp Ile Phe Gly Glu Thr Thr Leu Val 
        195                 200                 205             


Ala Ser Tyr Phe Leu Glu Trp Arg Ser Val Leu Gly Ser Glu Asn Gly 
    210                 215                 220                 


Val Thr Ser Leu Thr Val Glu Leu Met Gly Val Gly Thr Glu Ser Lys 
225                 230                 235                 240 


Val Ser Val Gly Ile Leu Asn Ile Lys Leu Glu Met Tyr Pro Pro Leu 
                245                 250                 255     


Asn Gln Thr Leu Ser Gln Glu Val Val Asn Thr Gln Leu Ala Leu Glu 
            260                 265                 270         


Arg Gln Lys Thr Ala Glu Lys Glu Arg Leu Phe Leu Val Tyr Ala Lys 
        275                 280                 285             


Gln Trp Trp Arg Glu Tyr Leu Gln Ile Arg Pro Ser His Asn Ser Arg 
    290                 295                 300                 


Leu Val Lys Ile Phe Ala Gln Asp Glu Asn Gly Ile Asn Arg Pro Val 
305                 310                 315                 320 


Cys Ser Tyr Val Lys Pro Leu Arg Ala Gly Arg Leu Leu Asp Thr Pro 
                325                 330                 335     


Arg Gln Ala Ala Arg Phe Val Asn Val Leu Gly Tyr Glu Arg Ala Pro 
            340                 345                 350         


Val Ile Gly Gly Gly Gly Lys Gln Glu Gln Trp Cys Thr Leu Leu Ala 
        355                 360                 365             


Phe Leu Cys Arg Asn Lys Gly Asp Cys Glu Asp His Ala Asn Leu Leu 
    370                 375                 380                 


Cys Ser Leu Leu Leu Gly Tyr Gly Leu Glu Ala Phe Val Cys Val Gly 
385                 390                 395                 400 


Thr Lys Ala Lys Gly Val Pro His Ala Trp Val Met Thr Cys Gly Thr 
                405                 410                 415     


Asp Gly Ala Ile Thr Phe Trp Glu Ser Leu Thr Gly His Arg Tyr Ile 
            420                 425                 430         


His Lys Pro Thr Asn Pro Asp Glu Pro Pro Val Ala Glu Gln Pro Lys 
        435                 440                 445             


Pro Leu Tyr Pro Tyr Arg Thr Ile Gly Cys Val Phe Asn His Gln Met 
    450                 455                 460                 


Phe Leu Gly Asn Cys Gln Pro Ser Asp Ala Val Glu Thr Cys Val Phe 
465                 470                 475                 480 


Asp Leu Asn Asp Glu Ser Lys Trp Lys Pro Met Ser Glu Glu Ala Ile 
                485                 490                 495     


Lys Ser Val Cys Ala Pro Gly Ala Thr Thr Ser Leu Pro Pro Phe Pro 
            500                 505                 510         


Pro Leu Cys Ala Ser Thr Ile Asp Ala Ser Val Thr Ser Asn Glu Ile 
        515                 520                 525             


Glu Met Gln Leu Arg Leu Leu Val Ser Glu His Arg Lys Asp Leu Gly 
    530                 535                 540                 


Leu Thr Thr Val Trp Glu Asp Gln Leu Ser Tyr Leu Leu Ser Pro Ala 
545                 550                 555                 560 


Leu Ala Ser Tyr Glu Phe Glu Arg Thr Thr Ser Ile Ser Ala Gly Asn 
                565                 570                 575     


Glu Glu Phe Gln Asp Ala Ile Arg Arg Ala Val Pro Asp Gly His Thr 
            580                 585                 590         


Phe Lys Gly Phe Pro Ile His Phe Val Tyr Arg Asn Ala Arg Arg Ala 
        595                 600                 605             


Phe Ala Thr Cys Leu Arg Ser Pro Phe Cys Glu Glu Ile Ile Cys Cys 
    610                 615                 620                 


Arg Gly Asp Gln Val Arg Leu Ala Val Arg Val Arg Val Phe Thr Tyr 
625                 630                 635                 640 


Pro Glu Ser Ala Cys Ala Val Trp Ile Met Phe Ala Cys Lys Tyr Arg 
                645                 650                 655     


Ser Val Leu 
            


<210>  1117
<211>  172
<212>  PRT
<213>  Human

<400>  1117

Met Ala Ser Asp Glu Gly Lys Leu Phe Val Gly Gly Leu Ser Phe Asp 
1               5                   10                  15      


Thr Asn Glu Gln Ser Leu Glu Gln Val Phe Ser Lys Tyr Gly Gln Ile 
            20                  25                  30          


Ser Glu Val Val Val Val Lys Asp Arg Glu Thr Gln Arg Ser Arg Gly 
        35                  40                  45              


Phe Gly Phe Val Thr Phe Glu Asn Ile Asp Asp Ala Lys Asp Ala Met 
    50                  55                  60                  


Met Ala Met Asn Gly Lys Ser Val Asp Gly Arg Gln Ile Arg Val Asp 
65                  70                  75                  80  


Gln Ala Gly Lys Ser Ser Asp Asn Arg Ser Arg Gly Tyr Arg Gly Gly 
                85                  90                  95      


Ser Ala Gly Gly Arg Gly Phe Phe Arg Gly Gly Arg Gly Arg Gly Arg 
            100                 105                 110         


Gly Phe Ser Arg Gly Gly Gly Asp Arg Gly Tyr Gly Gly Asn Arg Phe 
        115                 120                 125             


Glu Ser Arg Ser Gly Gly Tyr Gly Gly Ser Arg Asp Tyr Tyr Ser Ser 
    130                 135                 140                 


Arg Ser Gln Ser Gly Gly Tyr Ser Asp Arg Ser Ser Gly Gly Ser Tyr 
145                 150                 155                 160 


Arg Asp Ser Tyr Asp Ser Tyr Ala Thr His Asn Glu 
                165                 170         


<210>  1118
<211>  319
<212>  PRT
<213>  Human

<400>  1118

Met Ala Ser Ser Ala Ala Gly Cys Val Val Ile Val Gly Ser Gly Val 
1               5                   10                  15      


Ile Gly Arg Ser Trp Ala Met Leu Phe Ala Ser Gly Gly Phe Gln Val 
            20                  25                  30          


Lys Leu Tyr Asp Ile Glu Gln Gln Gln Ile Arg Asn Ala Leu Glu Asn 
        35                  40                  45              


Ile Arg Lys Glu Met Lys Leu Leu Glu Gln Ala Gly Ser Leu Lys Gly 
    50                  55                  60                  


Ser Leu Ser Val Glu Glu Gln Leu Ser Leu Ile Ser Gly Cys Pro Asn 
65                  70                  75                  80  


Ile Gln Glu Ala Val Glu Gly Ala Met His Ile Gln Glu Cys Val Pro 
                85                  90                  95      


Glu Asp Leu Glu Leu Lys Lys Lys Ile Phe Ala Gln Leu Asp Ser Ile 
            100                 105                 110         


Ile Asp Asp Arg Val Ile Leu Ser Ser Ser Thr Ser Cys Leu Met Pro 
        115                 120                 125             


Ser Lys Leu Phe Ala Gly Leu Val His Val Lys Gln Cys Ile Val Ala 
    130                 135                 140                 


His Pro Val Asn Pro Pro Tyr Tyr Ile Pro Leu Val Glu Leu Val Pro 
145                 150                 155                 160 


His Pro Glu Thr Ala Pro Thr Thr Val Asp Arg Thr His Ala Leu Met 
                165                 170                 175     


Lys Lys Ile Gly Gln Cys Pro Met Arg Val Gln Lys Glu Val Ala Gly 
            180                 185                 190         


Phe Val Leu Asn Arg Leu Gln Tyr Ala Ile Ile Ser Glu Ala Trp Arg 
        195                 200                 205             


Leu Val Glu Glu Gly Ile Val Ser Pro Ser Asp Leu Asp Leu Val Met 
    210                 215                 220                 


Ser Glu Gly Leu Gly Met Arg Tyr Ala Phe Ile Gly Pro Leu Glu Thr 
225                 230                 235                 240 


Met His Leu Asn Ala Glu Gly Met Leu Ser Tyr Cys Asp Arg Tyr Ser 
                245                 250                 255     


Glu Gly Ile Lys His Val Leu Gln Thr Phe Gly Pro Ile Pro Glu Phe 
            260                 265                 270         


Ser Arg Ala Thr Ala Glu Lys Val Asn Gln Asp Met Cys Met Lys Val 
        275                 280                 285             


Pro Asp Asp Pro Glu His Leu Ala Ala Arg Arg Gln Trp Arg Asp Glu 
    290                 295                 300                 


Cys Leu Met Arg Leu Ala Lys Leu Lys Ser Gln Val Gln Pro Gln 
305                 310                 315                 


<210>  1119
<211>  860
<212>  PRT
<213>  Human

<400>  1119

Met Ser Arg Gly Gly Ser Tyr Pro His Leu Leu Trp Asp Val Arg Lys 
1               5                   10                  15      


Arg Ser Leu Gly Leu Glu Asp Pro Ser Arg Leu Arg Ser Arg Tyr Leu 
            20                  25                  30          


Gly Arg Arg Glu Phe Ile Gln Arg Leu Lys Leu Glu Ala Thr Leu Asn 
        35                  40                  45              


Val His Asp Gly Cys Val Asn Thr Ile Cys Trp Asn Asp Thr Gly Glu 
    50                  55                  60                  


Tyr Ile Leu Ser Gly Ser Asp Asp Thr Lys Leu Val Ile Ser Asn Pro 
65                  70                  75                  80  


Tyr Ser Arg Lys Val Leu Thr Thr Ile Arg Ser Gly His Arg Ala Asn 
                85                  90                  95      


Ile Phe Ser Ala Lys Phe Leu Pro Cys Thr Asn Asp Lys Gln Ile Val 
            100                 105                 110         


Ser Cys Ser Gly Asp Gly Val Ile Phe Tyr Thr Asn Val Glu Gln Asp 
        115                 120                 125             


Ala Glu Thr Asn Arg Gln Cys Gln Phe Thr Cys His Tyr Gly Thr Thr 
    130                 135                 140                 


Tyr Glu Ile Met Thr Val Pro Asn Asp Pro Tyr Thr Phe Leu Ser Cys 
145                 150                 155                 160 


Gly Glu Asp Gly Thr Val Arg Trp Phe Asp Thr Arg Ile Lys Thr Ser 
                165                 170                 175     


Cys Thr Lys Glu Asp Cys Lys Asp Asp Ile Leu Ile Asn Cys Arg Arg 
            180                 185                 190         


Ala Ala Thr Ser Val Ala Ile Cys Pro Pro Ile Pro Tyr Tyr Leu Ala 
        195                 200                 205             


Val Gly Cys Ser Asp Ser Ser Val Arg Ile Tyr Asp Arg Arg Met Leu 
    210                 215                 220                 


Gly Thr Arg Ala Thr Gly Asn Tyr Ala Gly Arg Gly Thr Thr Gly Met 
225                 230                 235                 240 


Val Ala Arg Phe Ile Pro Ser His Leu Asn Asn Lys Ser Cys Arg Val 
                245                 250                 255     


Thr Ser Leu Cys Tyr Ser Glu Asp Gly Gln Glu Ile Leu Val Ser Tyr 
            260                 265                 270         


Ser Ser Asp Tyr Ile Tyr Leu Phe Asp Pro Lys Asp Asp Thr Ala Arg 
        275                 280                 285             


Glu Leu Lys Thr Pro Ser Ala Glu Glu Arg Arg Glu Glu Leu Arg Gln 
    290                 295                 300                 


Pro Pro Val Lys Arg Leu Arg Leu Arg Gly Asp Trp Ser Asp Thr Gly 
305                 310                 315                 320 


Pro Arg Ala Arg Pro Glu Ser Glu Arg Glu Arg Asp Gly Glu Gln Ser 
                325                 330                 335     


Pro Asn Val Ser Leu Met Gln Arg Met Ser Asp Met Leu Ser Arg Trp 
            340                 345                 350         


Phe Glu Glu Ala Ser Glu Val Ala Gln Ser Asn Arg Gly Arg Gly Arg 
        355                 360                 365             


Ser Arg Pro Arg Gly Gly Thr Ser Gln Ser Asp Ile Ser Thr Leu Pro 
    370                 375                 380                 


Thr Val Pro Ser Ser Pro Asp Leu Glu Val Ser Glu Thr Ala Met Glu 
385                 390                 395                 400 


Val Asp Thr Pro Ala Glu Gln Phe Leu Gln Pro Ser Thr Ser Ser Thr 
                405                 410                 415     


Met Ser Ala Gln Ala His Ser Thr Ser Ser Pro Thr Glu Ser Pro His 
            420                 425                 430         


Ser Thr Pro Leu Leu Ser Ser Pro Asp Ser Glu Gln Arg Gln Ser Val 
        435                 440                 445             


Glu Ala Ser Gly His His Thr His His Gln Ser Asp Asn Asn Asn Glu 
    450                 455                 460                 


Lys Leu Ser Pro Lys Pro Gly Thr Gly Glu Pro Val Leu Ser Leu His 
465                 470                 475                 480 


Tyr Ser Thr Glu Gly Thr Thr Thr Ser Thr Ile Lys Leu Asn Phe Thr 
                485                 490                 495     


Asp Glu Trp Ser Ser Ile Ala Ser Ser Ser Arg Gly Ile Gly Ser His 
            500                 505                 510         


Cys Lys Ser Glu Gly Gln Glu Glu Ser Phe Val Pro Gln Ser Ser Val 
        515                 520                 525             


Gln Pro Pro Glu Gly Asp Ser Glu Thr Lys Ala Pro Glu Glu Ser Ser 
    530                 535                 540                 


Glu Asp Val Thr Lys Tyr Gln Glu Gly Val Ser Ala Glu Asn Pro Val 
545                 550                 555                 560 


Glu Asn His Ile Asn Ile Thr Gln Ser Asp Lys Phe Thr Ala Lys Pro 
                565                 570                 575     


Leu Asp Ser Asn Ser Gly Glu Arg Asn Asp Leu Asn Leu Asp Arg Ser 
            580                 585                 590         


Cys Gly Val Pro Glu Glu Ser Ala Ser Ser Glu Lys Ala Lys Glu Pro 
        595                 600                 605             


Glu Thr Ser Asp Gln Thr Ser Thr Glu Ser Ala Thr Asn Glu Asn Asn 
    610                 615                 620                 


Thr Asn Pro Glu Pro Gln Phe Gln Thr Glu Ala Thr Gly Pro Ser Ala 
625                 630                 635                 640 


His Glu Glu Thr Ser Thr Arg Asp Ser Ala Leu Gln Asp Thr Asp Asp 
                645                 650                 655     


Ser Asp Asp Asp Pro Val Leu Ile Pro Gly Ala Arg Tyr Arg Ala Gly 
            660                 665                 670         


Pro Gly Asp Arg Arg Ser Ala Val Ala Arg Ile Gln Glu Phe Phe Arg 
        675                 680                 685             


Arg Arg Lys Glu Arg Lys Glu Met Glu Glu Leu Asp Thr Leu Asn Ile 
    690                 695                 700                 


Arg Arg Pro Leu Val Lys Met Val Tyr Lys Gly His Arg Asn Ser Arg 
705                 710                 715                 720 


Thr Met Ile Lys Glu Ala Asn Phe Trp Gly Ala Asn Phe Val Met Ser 
                725                 730                 735     


Gly Ser Asp Cys Gly His Ile Phe Ile Trp Asp Arg His Thr Ala Glu 
            740                 745                 750         


His Leu Met Leu Leu Glu Ala Asp Asn His Val Val Asn Cys Leu Gln 
        755                 760                 765             


Pro His Pro Phe Asp Pro Ile Leu Ala Ser Ser Gly Ile Asp Tyr Asp 
    770                 775                 780                 


Ile Lys Ile Trp Ser Pro Leu Glu Glu Ser Arg Ile Phe Asn Arg Lys 
785                 790                 795                 800 


Leu Ala Asp Glu Val Ile Thr Arg Asn Glu Leu Met Leu Glu Glu Thr 
                805                 810                 815     


Arg Asn Thr Ile Thr Val Pro Ala Ser Phe Met Leu Arg Met Leu Ala 
            820                 825                 830         


Ser Leu Asn His Ile Arg Ala Asp Arg Leu Glu Gly Asp Arg Ser Glu 
        835                 840                 845             


Gly Ser Gly Gln Glu Asn Glu Asn Glu Asp Glu Glu 
    850                 855                 860 


<210>  1120
<211>  113
<212>  PRT
<213>  Human

<400>  1120

Met Glu Asp Tyr Gln Ala Ala Glu Glu Thr Ala Phe Val Val Asp Glu 
1               5                   10                  15      


Val Ser Asn Ile Val Lys Glu Ala Ile Glu Ser Ala Ile Gly Gly Asn 
            20                  25                  30          


Ala Tyr Gln His Ser Lys Val Asn Gln Trp Thr Thr Asn Val Val Glu 
        35                  40                  45              


Gln Thr Leu Ser Gln Leu Thr Lys Leu Gly Lys Pro Phe Lys Tyr Ile 
    50                  55                  60                  


Val Thr Cys Val Ile Met Gln Lys Asn Gly Ala Gly Leu His Thr Ala 
65                  70                  75                  80  


Ser Ser Cys Phe Trp Asp Ser Ser Thr Asp Gly Ser Cys Thr Val Arg 
                85                  90                  95      


Trp Glu Asn Lys Thr Met Tyr Cys Ile Val Ser Ala Phe Gly Leu Ser 
            100                 105                 110         


Ile 
    


<210>  1121
<211>  164
<212>  PRT
<213>  Human

<400>  1121

Met Ser Val Asn Met Asp Glu Leu Arg His Gln Val Met Ile Asn Gln 
1               5                   10                  15      


Phe Val Leu Ala Ala Gly Cys Ala Ala Asp Gln Ala Lys Gln Leu Leu 
            20                  25                  30          


Gln Ala Ala His Trp Gln Phe Glu Thr Ala Leu Ser Thr Phe Phe Gln 
        35                  40                  45              


Glu Thr Asn Ile Pro Asn Ser His His His His Gln Met Met Cys Thr 
    50                  55                  60                  


Pro Ser Asn Thr Pro Ala Thr Pro Pro Asn Phe Pro Asp Ala Leu Ala 
65                  70                  75                  80  


Met Phe Ser Lys Leu Arg Ala Ser Glu Gly Leu Gln Ser Ser Asn Ser 
                85                  90                  95      


Pro Met Thr Ala Ala Ala Cys Ser Pro Pro Ala Asn Phe Ser Pro Phe 
            100                 105                 110         


Trp Ala Ser Ser Pro Pro Ser His Gln Ala Pro Trp Ile Pro Pro Ser 
        115                 120                 125             


Ser Pro Thr Thr Phe His His Leu His Arg Pro Gln Pro Thr Trp Pro 
    130                 135                 140                 


Pro Gly Ala Gln Gln Gly Gly Ala Gln Gln Lys Ala Met Ala Ala Met 
145                 150                 155                 160 


Asp Gly Gln Arg 
                


<210>  1122
<211>  759
<212>  PRT
<213>  Human

<400>  1122

Met Ser Lys Arg Leu Arg Ser Ser Glu Val Cys Ala Asp Cys Ser Gly 
1               5                   10                  15      


Pro Asp Pro Ser Trp Ala Ser Val Asn Arg Gly Thr Phe Leu Cys Asp 
            20                  25                  30          


Glu Cys Cys Ser Val His Arg Ser Leu Gly Arg His Ile Ser Gln Val 
        35                  40                  45              


Arg His Leu Lys His Thr Pro Trp Pro Pro Thr Leu Leu Gln Met Val 
    50                  55                  60                  


Glu Thr Leu Tyr Asn Asn Gly Ala Asn Ser Ile Trp Glu His Ser Leu 
65                  70                  75                  80  


Leu Asp Pro Ala Ser Ile Met Ser Gly Arg Arg Lys Ala Asn Pro Gln 
                85                  90                  95      


Asp Lys Val His Pro Asn Lys Ala Glu Phe Ile Arg Ala Lys Tyr Gln 
            100                 105                 110         


Met Leu Ala Phe Val His Arg Leu Pro Cys Arg Asp Asp Asp Ser Val 
        115                 120                 125             


Thr Ala Lys Asp Leu Ser Lys Gln Leu His Ser Ser Val Arg Thr Gly 
    130                 135                 140                 


Asn Leu Glu Thr Cys Leu Arg Leu Leu Ser Leu Gly Ala Gln Ala Asn 
145                 150                 155                 160 


Phe Phe His Pro Glu Lys Gly Asn Thr Pro Leu His Val Ala Ser Lys 
                165                 170                 175     


Ala Gly Gln Ile Leu Gln Ala Glu Leu Leu Ala Val Tyr Gly Ala Asp 
            180                 185                 190         


Pro Gly Thr Gln Asp Ser Ser Gly Lys Thr Pro Val Asp Tyr Ala Arg 
        195                 200                 205             


Gln Gly Gly His His Glu Leu Ala Glu Arg Leu Val Glu Ile Gln Tyr 
    210                 215                 220                 


Glu Leu Thr Asp Arg Leu Ala Phe Tyr Leu Cys Gly Arg Lys Pro Asp 
225                 230                 235                 240 


His Lys Asn Gly Gln His Phe Ile Ile Pro Gln Met Ala Asp Ser Ser 
                245                 250                 255     


Leu Asp Leu Ser Glu Leu Ala Lys Ala Ala Lys Lys Lys Leu Gln Ser 
            260                 265                 270         


Leu Ser Asn His Leu Phe Glu Glu Leu Ala Met Asp Val Tyr Asp Glu 
        275                 280                 285             


Val Asp Arg Arg Glu Thr Asp Ala Val Trp Leu Ala Thr Gln Asn His 
    290                 295                 300                 


Ser Ala Leu Val Thr Glu Thr Thr Val Val Pro Phe Leu Pro Val Asn 
305                 310                 315                 320 


Pro Glu Tyr Ser Ser Thr Arg Asn Gln Gly Arg Gln Lys Leu Ala Arg 
                325                 330                 335     


Phe Asn Ala His Glu Phe Ala Thr Leu Val Ile Asp Ile Leu Ser Asp 
            340                 345                 350         


Ala Lys Arg Arg Gln Gln Gly Ser Ser Leu Ser Gly Ser Lys Asp Asn 
        355                 360                 365             


Val Glu Leu Ile Leu Lys Thr Ile Asn Asn Gln His Ser Val Glu Ser 
    370                 375                 380                 


Gln Asp Asn Asp Gln Pro Asp Tyr Asp Ser Val Ala Ser Asp Glu Asp 
385                 390                 395                 400 


Thr Asp Leu Glu Thr Thr Ala Ser Lys Thr Asn Arg Gln Lys Ser Leu 
                405                 410                 415     


Asp Ser Asp Leu Ser Asp Gly Pro Val Thr Val Gln Glu Phe Met Glu 
            420                 425                 430         


Val Lys Asn Ala Leu Val Ala Ser Glu Ala Lys Ile Gln Gln Leu Met 
        435                 440                 445             


Lys Val Asn Asn Asn Leu Ser Asp Glu Leu Arg Ile Met Gln Lys Lys 
    450                 455                 460                 


Leu Gln Thr Leu Gln Ser Glu Asn Ser Asn Leu Arg Lys Gln Ala Thr 
465                 470                 475                 480 


Thr Asn Val Tyr Gln Val Gln Thr Gly Ser Glu Tyr Thr Asp Thr Ser 
                485                 490                 495     


Asn His Ser Ser Leu Lys Arg Arg Pro Ser Ala Arg Gly Ser Arg Pro 
            500                 505                 510         


Met Ser Met Tyr Glu Thr Gly Ser Gly Gln Lys Pro Tyr Leu Pro Met 
        515                 520                 525             


Gly Glu Ala Ser Arg Pro Glu Glu Ser Arg Met Arg Leu Gln Pro Phe 
    530                 535                 540                 


Pro Ala His Ile Gly Arg Ser Ala Leu Val Thr Ser Ser Ser Ser Leu 
545                 550                 555                 560 


Pro Ser Phe Pro Ser Thr Leu Ser Trp Ser Arg Asp Glu Ser Ala Arg 
                565                 570                 575     


Arg Ala Ser Arg Leu Glu Lys Gln Asn Ser Thr Pro Glu Ser Asp Tyr 
            580                 585                 590         


Asp Asn Thr Pro Asn Asp Met Glu Pro Asp Gly Met Gly Ser Ser Arg 
        595                 600                 605             


Lys Gly Arg Gln Arg Ser Met Val Trp Pro Gly Asp Gly Leu Val Pro 
    610                 615                 620                 


Asp Thr Ala Glu Pro His Val Ala Pro Ser Pro Thr Leu Pro Ser Thr 
625                 630                 635                 640 


Glu Asp Val Ile Arg Lys Thr Glu Gln Ile Thr Lys Asn Ile Gln Glu 
                645                 650                 655     


Leu Leu Arg Ala Ala Gln Glu Asn Lys His Asp Ser Tyr Ile Pro Cys 
            660                 665                 670         


Ser Glu Arg Ile His Val Ala Val Thr Glu Met Ala Ala Leu Phe Pro 
        675                 680                 685             


Lys Lys Pro Lys Ser Asp Met Val Arg Thr Ser Leu Arg Leu Leu Thr 
    690                 695                 700                 


Ser Ser Ala Tyr Arg Leu Gln Ser Glu Cys Lys Lys Thr Leu Pro Gly 
705                 710                 715                 720 


Asp Pro Gly Ser Pro Thr Asp Val Gln Leu Val Thr Gln Gln Val Ile 
                725                 730                 735     


Gln Cys Ala Tyr Asp Ile Ala Lys Ala Ala Lys Gln Leu Val Thr Ile 
            740                 745                 750         


Thr Thr Lys Glu Asn Asn Asn 
        755                 


<210>  1123
<211>  423
<212>  PRT
<213>  Human

<400>  1123

Met Gly Gln Gln Pro Ile Thr Phe Leu Arg Gln Val Met Ala Leu Cys 
1               5                   10                  15      


Thr Tyr Pro Asn Leu Leu Asp Ser Pro Ser Phe Pro Glu Asp Ala Lys 
            20                  25                  30          


Lys Arg Ala Arg Arg Ile Leu Gln Ala Cys Gly Gly Asn Ser Leu Gly 
        35                  40                  45              


Ser Tyr Ser Ala Ser Gln Gly Val Asn Cys Ile Arg Glu Asp Val Ala 
    50                  55                  60                  


Ala Tyr Ile Thr Arg Arg Asp Gly Gly Val Pro Ala Asp Pro Asp Asn 
65                  70                  75                  80  


Ile Tyr Leu Thr Thr Gly Ala Ser Asp Gly Ile Ser Thr Ile Leu Lys 
                85                  90                  95      


Ile Leu Val Ser Gly Gly Gly Lys Ser Arg Thr Gly Val Met Ile Pro 
            100                 105                 110         


Ile Pro Gln Tyr Pro Leu Tyr Ser Ala Val Ile Ser Glu Leu Asp Ala 
        115                 120                 125             


Ile Gln Val Asn Tyr Tyr Leu Asp Glu Glu Asn Cys Trp Ala Leu Asn 
    130                 135                 140                 


Val Asn Glu Leu Arg Arg Ala Val Gln Glu Ala Lys Asp His Cys Asp 
145                 150                 155                 160 


Pro Lys Val Leu Cys Ile Ile Asn Pro Gly Asn Pro Thr Gly Gln Val 
                165                 170                 175     


Gln Ser Arg Lys Cys Ile Glu Asp Val Ile His Phe Ala Trp Glu Glu 
            180                 185                 190         


Lys Leu Phe Leu Leu Ala Asp Glu Val Tyr Gln Asp Asn Val Tyr Ser 
        195                 200                 205             


Pro Asp Cys Arg Phe His Ser Phe Lys Lys Val Leu Tyr Glu Met Gly 
    210                 215                 220                 


Pro Glu Tyr Ser Ser Asn Val Glu Leu Ala Ser Phe His Ser Thr Ser 
225                 230                 235                 240 


Lys Gly Tyr Met Gly Glu Cys Gly Tyr Arg Gly Gly Tyr Met Glu Val 
                245                 250                 255     


Ile Asn Leu His Pro Glu Ile Lys Gly Gln Leu Val Lys Leu Leu Ser 
            260                 265                 270         


Val Arg Leu Cys Pro Pro Val Ser Gly Gln Ala Ala Met Asp Ile Val 
        275                 280                 285             


Val Asn Pro Pro Val Ala Gly Glu Glu Ser Phe Glu Gln Phe Ser Arg 
    290                 295                 300                 


Glu Lys Glu Ser Val Leu Gly Asn Leu Ala Lys Lys Ala Lys Leu Thr 
305                 310                 315                 320 


Glu Asp Leu Phe Asn Gln Val Pro Gly Ile His Cys Asn Pro Leu Gln 
                325                 330                 335     


Gly Ala Met Tyr Ala Phe Pro Arg Ile Phe Ile Pro Ala Lys Ala Val 
            340                 345                 350         


Glu Ala Ala Gln Ala His Gln Met Ala Pro Asp Met Phe Tyr Cys Met 
        355                 360                 365             


Lys Leu Leu Glu Glu Thr Gly Ile Cys Val Val Pro Gly Ser Gly Phe 
    370                 375                 380                 


Gly Gln Arg Glu Gly Thr Tyr His Phe Arg Met Thr Ile Leu Pro Pro 
385                 390                 395                 400 


Val Glu Lys Leu Lys Thr Val Leu Gln Lys Val Lys Asp Phe His Ile 
                405                 410                 415     


Asn Phe Leu Glu Lys Tyr Ala 
            420             


<210>  1124
<211>  486
<212>  PRT
<213>  Human

<400>  1124

Met Trp Lys Ser Val Val Gly His Asp Val Ser Val Ser Val Glu Thr 
1               5                   10                  15      


Gln Gly Asp Asp Trp Asp Thr Asp Pro Asp Phe Val Asn Asp Ile Ser 
            20                  25                  30          


Glu Lys Glu Gln Arg Trp Gly Ala Lys Thr Ile Glu Gly Ser Gly Arg 
        35                  40                  45              


Thr Glu His Ile Asn Ile His Gln Leu Arg Asn Lys Val Ser Glu Glu 
    50                  55                  60                  


His Asp Val Leu Arg Lys Lys Glu Met Glu Ser Gly Pro Lys Ala Ser 
65                  70                  75                  80  


His Gly Tyr Gly Gly Arg Phe Gly Val Glu Arg Asp Arg Met Asp Lys 
                85                  90                  95      


Ser Ala Val Gly His Glu Tyr Val Ala Glu Val Glu Lys His Ser Ser 
            100                 105                 110         


Gln Thr Asp Ala Ala Lys Gly Phe Gly Gly Lys Tyr Gly Val Glu Arg 
        115                 120                 125             


Asp Arg Ala Asp Lys Ser Ala Val Gly Phe Asp Tyr Lys Gly Glu Val 
    130                 135                 140                 


Glu Lys His Thr Ser Gln Lys Asp Tyr Ser Arg Gly Phe Gly Gly Arg 
145                 150                 155                 160 


Tyr Gly Val Glu Lys Asp Lys Trp Asp Lys Ala Ala Leu Gly Tyr Asp 
                165                 170                 175     


Tyr Lys Gly Glu Thr Glu Lys His Glu Ser Gln Arg Asp Tyr Ala Lys 
            180                 185                 190         


Gly Phe Gly Gly Gln Tyr Gly Ile Gln Lys Asp Arg Val Asp Lys Ser 
        195                 200                 205             


Ala Val Gly Phe Asn Glu Met Glu Ala Pro Thr Thr Ala Tyr Lys Lys 
    210                 215                 220                 


Thr Thr Pro Ile Glu Ala Ala Ser Ser Gly Thr Arg Gly Leu Lys Ala 
225                 230                 235                 240 


Lys Phe Glu Ser Met Ala Glu Glu Lys Arg Lys Arg Glu Glu Glu Glu 
                245                 250                 255     


Lys Ala Gln Gln Val Ala Arg Arg Gln Gln Glu Arg Lys Ala Val Thr 
            260                 265                 270         


Lys Arg Ser Pro Glu Ala Pro Gln Pro Val Ile Ala Met Glu Glu Pro 
        275                 280                 285             


Ala Val Pro Ala Pro Leu Pro Lys Lys Ile Ser Ser Glu Ala Trp Pro 
    290                 295                 300                 


Pro Val Gly Thr Pro Pro Ser Ser Glu Ser Glu Pro Val Arg Thr Ser 
305                 310                 315                 320 


Arg Glu His Pro Val Pro Leu Leu Pro Ile Arg Gln Thr Leu Pro Glu 
                325                 330                 335     


Asp Asn Glu Glu Pro Pro Ala Leu Pro Pro Arg Thr Leu Glu Gly Leu 
            340                 345                 350         


Gln Val Glu Glu Glu Pro Val Tyr Glu Ala Glu Pro Glu Pro Glu Pro 
        355                 360                 365             


Glu Pro Glu Pro Glu Pro Glu Asn Asp Tyr Glu Asp Val Glu Glu Met 
    370                 375                 380                 


Asp Arg His Glu Gln Glu Asp Glu Pro Glu Gly Asp Tyr Glu Glu Val 
385                 390                 395                 400 


Leu Glu Pro Glu Asp Ser Ser Phe Ser Ser Ala Leu Ala Gly Ser Ser 
                405                 410                 415     


Gly Cys Pro Ala Gly Ala Gly Ala Gly Ala Val Ala Leu Gly Ile Ser 
            420                 425                 430         


Ala Val Ala Leu Tyr Asp Tyr Gln Gly Glu Gly Ser Asp Glu Leu Ser 
        435                 440                 445             


Phe Asp Pro Asp Asp Val Ile Thr Asp Ile Glu Met Val Asp Glu Gly 
    450                 455                 460                 


Trp Trp Arg Gly Arg Cys His Gly His Phe Gly Leu Phe Pro Ala Asn 
465                 470                 475                 480 


Tyr Val Lys Leu Leu Glu 
                485     


<210>  1125
<211>  573
<212>  PRT
<213>  Human

<400>  1125

Met Leu Arg Leu Pro Thr Val Phe Arg Gln Met Arg Pro Val Ser Arg 
1               5                   10                  15      


Val Leu Ala Pro His Leu Thr Arg Ala Tyr Ala Lys Asp Val Lys Phe 
            20                  25                  30          


Gly Ala Asp Ala Arg Ala Leu Met Leu Gln Gly Val Asp Leu Leu Ala 
        35                  40                  45              


Asp Ala Val Ala Val Thr Met Gly Pro Lys Gly Arg Thr Val Ile Ile 
    50                  55                  60                  


Glu Gln Ser Trp Gly Ser Pro Lys Val Thr Lys Asp Gly Val Thr Val 
65                  70                  75                  80  


Ala Lys Ser Ile Asp Leu Lys Asp Lys Tyr Lys Asn Ile Gly Ala Lys 
                85                  90                  95      


Leu Val Gln Asp Val Ala Asn Asn Thr Asn Glu Glu Ala Gly Asp Gly 
            100                 105                 110         


Thr Thr Thr Ala Thr Val Leu Ala Arg Ser Ile Ala Lys Glu Gly Phe 
        115                 120                 125             


Glu Lys Ile Ser Lys Gly Ala Asn Pro Val Glu Ile Arg Arg Gly Val 
    130                 135                 140                 


Met Leu Ala Val Asp Ala Val Ile Ala Glu Leu Lys Lys Gln Ser Lys 
145                 150                 155                 160 


Pro Val Thr Thr Pro Glu Glu Ile Ala Gln Val Ala Thr Ile Ser Ala 
                165                 170                 175     


Asn Gly Asp Lys Glu Ile Gly Asn Ile Ile Ser Asp Ala Met Lys Lys 
            180                 185                 190         


Val Gly Arg Lys Gly Val Ile Thr Val Lys Asp Gly Lys Thr Leu Asn 
        195                 200                 205             


Asp Glu Leu Glu Ile Ile Glu Gly Met Lys Phe Asp Arg Gly Tyr Ile 
    210                 215                 220                 


Ser Pro Tyr Phe Ile Asn Thr Ser Lys Gly Gln Lys Cys Glu Phe Gln 
225                 230                 235                 240 


Asp Ala Tyr Val Leu Leu Ser Glu Lys Lys Ile Ser Ser Ile Gln Ser 
                245                 250                 255     


Ile Val Pro Ala Leu Glu Ile Ala Asn Ala His Arg Lys Pro Leu Val 
            260                 265                 270         


Ile Ile Ala Glu Asp Val Asp Gly Glu Ala Leu Ser Thr Leu Val Leu 
        275                 280                 285             


Asn Arg Leu Lys Val Gly Leu Gln Val Val Ala Val Lys Ala Pro Gly 
    290                 295                 300                 


Phe Gly Asp Asn Arg Lys Asn Gln Leu Lys Asp Met Ala Ile Ala Thr 
305                 310                 315                 320 


Gly Gly Ala Val Phe Gly Glu Glu Gly Leu Thr Leu Asn Leu Glu Asp 
                325                 330                 335     


Val Gln Pro His Asp Leu Gly Lys Val Gly Glu Val Ile Val Thr Lys 
            340                 345                 350         


Asp Asp Ala Met Leu Leu Lys Gly Lys Gly Asp Lys Ala Gln Ile Glu 
        355                 360                 365             


Lys Arg Ile Gln Glu Ile Ile Glu Gln Leu Asp Val Thr Thr Ser Glu 
    370                 375                 380                 


Tyr Glu Lys Glu Lys Leu Asn Glu Arg Leu Ala Lys Leu Ser Asp Gly 
385                 390                 395                 400 


Val Ala Val Leu Lys Val Gly Gly Thr Ser Asp Val Glu Val Asn Glu 
                405                 410                 415     


Lys Lys Asp Arg Val Thr Asp Ala Leu Asn Ala Thr Arg Ala Ala Val 
            420                 425                 430         


Glu Glu Gly Ile Val Leu Gly Gly Gly Cys Ala Leu Leu Arg Cys Ile 
        435                 440                 445             


Pro Ala Leu Asp Ser Leu Thr Pro Ala Asn Glu Asp Gln Lys Ile Gly 
    450                 455                 460                 


Ile Glu Ile Ile Lys Arg Thr Leu Lys Ile Pro Ala Met Thr Ile Ala 
465                 470                 475                 480 


Lys Asn Ala Gly Val Glu Gly Ser Leu Ile Val Glu Lys Ile Met Gln 
                485                 490                 495     


Ser Ser Ser Glu Val Gly Tyr Asp Ala Met Ala Gly Asp Phe Val Asn 
            500                 505                 510         


Met Val Glu Lys Gly Ile Ile Asp Pro Thr Lys Val Val Arg Thr Ala 
        515                 520                 525             


Leu Leu Asp Ala Ala Gly Val Ala Ser Leu Leu Thr Thr Ala Glu Val 
    530                 535                 540                 


Val Val Thr Glu Ile Pro Lys Glu Glu Lys Asp Pro Gly Met Gly Ala 
545                 550                 555                 560 


Met Gly Gly Met Gly Gly Gly Met Gly Gly Gly Met Phe 
                565                 570             


<210>  1126
<211>  282
<212>  PRT
<213>  Human

<400>  1126

Met Glu Arg Pro Ser Leu Arg Ala Leu Leu Leu Gly Ala Ala Gly Leu 
1               5                   10                  15      


Leu Leu Leu Leu Leu Pro Leu Ser Ser Ser Ser Ser Ser Asp Thr Cys 
            20                  25                  30          


Gly Pro Cys Glu Pro Ala Ser Cys Pro Pro Leu Pro Pro Leu Gly Cys 
        35                  40                  45              


Leu Leu Gly Glu Thr Arg Asp Ala Cys Gly Cys Cys Pro Met Cys Ala 
    50                  55                  60                  


Arg Gly Glu Gly Glu Pro Cys Gly Gly Gly Gly Ala Gly Arg Gly Tyr 
65                  70                  75                  80  


Cys Ala Pro Gly Met Glu Cys Val Lys Ser Arg Lys Arg Arg Lys Gly 
                85                  90                  95      


Lys Ala Gly Ala Ala Ala Gly Gly Pro Gly Val Ser Gly Val Cys Val 
            100                 105                 110         


Cys Lys Ser Arg Tyr Pro Val Cys Gly Ser Asp Gly Thr Thr Tyr Pro 
        115                 120                 125             


Ser Gly Cys Gln Leu Arg Ala Ala Ser Gln Arg Ala Glu Ser Arg Gly 
    130                 135                 140                 


Glu Lys Ala Ile Thr Gln Val Ser Lys Gly Thr Cys Glu Gln Gly Pro 
145                 150                 155                 160 


Ser Ile Val Thr Pro Pro Lys Asp Ile Trp Asn Val Thr Gly Ala Gln 
                165                 170                 175     


Val Tyr Leu Ser Cys Glu Val Ile Gly Ile Pro Thr Pro Val Leu Ile 
            180                 185                 190         


Trp Asn Lys Val Lys Arg Gly His Tyr Gly Val Gln Arg Thr Glu Leu 
        195                 200                 205             


Leu Pro Gly Asp Arg Asp Asn Leu Ala Ile Gln Thr Arg Gly Gly Pro 
    210                 215                 220                 


Glu Lys His Glu Val Thr Gly Trp Val Leu Val Ser Pro Leu Ser Lys 
225                 230                 235                 240 


Glu Asp Ala Gly Glu Tyr Glu Cys His Ala Ser Asn Ser Gln Gly Gln 
                245                 250                 255     


Ala Ser Ala Ser Ala Lys Ile Thr Val Val Asp Ala Leu His Glu Ile 
            260                 265                 270         


Pro Val Lys Lys Gly Glu Gly Ala Glu Leu 
        275                 280         


<210>  1127
<211>  2017
<212>  PRT
<213>  Human

<400>  1127

Met Thr Ser Arg Thr Lys Arg Arg Gln Lys Val Lys Ile Ser Ile Ser 
1               5                   10                  15      


Lys Ile Asn His Ser Ser Tyr Arg Lys Glu His Arg Pro Phe Trp Glu 
            20                  25                  30          


His Gln Pro Pro Pro His Gln Asn Trp Ala Val Gly Gly Arg Cys Gly 
        35                  40                  45              


Ala Gly Ala Arg Pro Gly Leu Ser Gln Arg Arg Gly Arg Glu Val Arg 
    50                  55                  60                  


Arg Glu Ala Gln Gly Gly Ala Ser Ser Arg Arg Leu Arg Ala Arg Leu 
65                  70                  75                  80  


Tyr Phe Ser Glu Ser Thr Ser Leu Pro Leu Asp Arg Arg Gly Ser Pro 
                85                  90                  95      


Gly Pro Leu Gly Pro Ala Pro His Gly Leu Arg Arg Ala Ala Pro Arg 
            100                 105                 110         


Gly Pro Ala Arg Arg Thr Pro Arg Ser Thr Ala Leu Thr Ser Arg Arg 
        115                 120                 125             


Arg Ala Gln Arg Pro Arg His Gly Asp Arg Leu Arg Leu Arg Ser Glu 
    130                 135                 140                 


Ala Arg Pro Arg Ala Ala Gly Asp Trp Pro Cys Ala Arg Gly Gly Ala 
145                 150                 155                 160 


Val Arg Pro Gly Arg Pro His Arg Pro Pro Arg Val Glu Ser Ala Arg 
                165                 170                 175     


Gly Ala His Ala Gly Arg Ala Ala Thr Asp Gln Leu Glu Arg Val Phe 
            180                 185                 190         


Leu Arg Leu Gly His Ala Glu Thr Asp Glu Gln Leu Gln Asn Ile Ile 
        195                 200                 205             


Ser Lys Phe Leu Pro Pro Val Leu Leu Lys Leu Ser Ser Thr Gln Glu 
    210                 215                 220                 


Gly Val Arg Lys Lys Val Met Glu Leu Leu Val His Leu Asn Lys Arg 
225                 230                 235                 240 


Ile Lys Ser Arg Pro Lys Ile Gln Leu Pro Val Glu Thr Leu Leu Val 
                245                 250                 255     


Gln Tyr Gln Asp Pro Ala Ala Val Ser Phe Val Thr Asn Phe Thr Ile 
            260                 265                 270         


Ile Tyr Val Lys Met Gly Tyr Pro Arg Leu Pro Val Glu Lys Gln Cys 
        275                 280                 285             


Glu Leu Ala Pro Thr Leu Leu Thr Ala Met Glu Gly Lys Pro Gln Pro 
    290                 295                 300                 


Gln Gln Asp Ser Leu Met His Leu Leu Ile Pro Thr Leu Phe His Met 
305                 310                 315                 320 


Lys Tyr Pro Val Glu Ser Ser Lys Ser Ala Ser Pro Phe Asn Leu Ala 
                325                 330                 335     


Glu Lys Pro Lys Thr Val Gln Leu Leu Leu Asp Phe Met Leu Asp Val 
            340                 345                 350         


Leu Leu Met Pro Tyr Gly Tyr Val Leu Asn Glu Ser Gln Ser Arg Gln 
        355                 360                 365             


Asn Ser Ser Ser Ala Gln Gly Ser Ser Ser Asn Ser Gly Gly Gly Ser 
    370                 375                 380                 


Gly Ile Pro Gln Pro Pro Pro Gly Met Ser Phe Tyr Ala Ala Lys Arg 
385                 390                 395                 400 


Val Ile Gly Asp Asn Pro Trp Thr Pro Glu Gln Leu Glu Gln Cys Lys 
                405                 410                 415     


Leu Gly Ile Val Lys Phe Ile Glu Ala Glu Gln Val Pro Glu Leu Glu 
            420                 425                 430         


Ala Val Leu His Leu Val Ile Ala Ser Ser Asp Thr Arg His Ser Val 
        435                 440                 445             


Ala Thr Ala Ala Asp Leu Glu Leu Lys Ser Lys Gln Ser Leu Ile Asp 
    450                 455                 460                 


Trp Asn Asn Pro Ala Ile Ile Asn Lys Met Tyr Lys Val Tyr Leu Gly 
465                 470                 475                 480 


Asp Ile Pro Leu Lys Thr Lys Glu Gly Ala Val Leu Lys Pro Glu Leu 
                485                 490                 495     


Lys Arg Asp Pro Val Ser Thr Arg Val Lys Leu Lys Ile Val Pro His 
            500                 505                 510         


Leu Leu Arg Ser Arg Gln Ala Ala Glu Thr Phe Pro Ala Asn Ile Gln 
        515                 520                 525             


Val Val Tyr Asp Gly Leu Phe Gly Thr Asn Thr Asn Ser Lys Leu Arg 
    530                 535                 540                 


Thr Leu Ser Leu Gln Phe Val His His Ile Cys Ile Thr Cys Pro Glu 
545                 550                 555                 560 


Ile Lys Ile Lys Pro Leu Gly Pro Met Leu Leu Asn Gly Leu Thr Lys 
                565                 570                 575     


Leu Ile Asn Glu Tyr Lys Glu Asp Pro Lys Leu Leu Ser Met Ala Tyr 
            580                 585                 590         


Ser Ala Val Gly Lys Leu Ser Ser Arg Met Pro His Leu Phe Thr Lys 
        595                 600                 605             


Asp Ile Ala Leu Val Gln Gln Leu Phe Glu Ala Leu Cys Lys Glu Glu 
    610                 615                 620                 


Pro Glu Thr Arg Leu Ala Ile Gln Glu Ala Leu Ser Met Met Val Gly 
625                 630                 635                 640 


Ala Tyr Ser Thr Leu Glu Gly Ala Gln Arg Thr Leu Met Glu Ala Leu 
                645                 650                 655     


Val Ala Ser Tyr Leu Ile Lys Pro Glu Val Gln Val Arg Gln Val Ala 
            660                 665                 670         


Val Lys Phe Ala Ser Thr Val Phe Pro Ser Asp His Ile Pro Ser Arg 
        675                 680                 685             


Tyr Leu Leu Leu Leu Ala Ala Gly Asp Pro Arg Glu Glu Val His Gly 
    690                 695                 700                 


Glu Ala Gln Arg Val Leu Arg Cys Leu Pro Gly Arg Asn Arg Lys Glu 
705                 710                 715                 720 


Ser Thr Ser Glu Gln Met Pro Ser Phe Pro Glu Met Val Tyr Tyr Ile 
                725                 730                 735     


Gln Glu Lys Ala Ser His Arg Met Lys Thr Pro Val Lys Tyr Met Thr 
            740                 745                 750         


Gly Thr Thr Val Leu Pro Phe Asn Pro Ala Ala Phe Gly Glu Ile Val 
        755                 760                 765             


Leu Tyr Leu Arg Met Cys Leu Ala His Ser Ala Gly Val Val Pro Thr 
    770                 775                 780                 


Ser Gln Ser Leu Ala Asp Met Gln Asp His Ala Pro Ala Ile Gly Arg 
785                 790                 795                 800 


Tyr Ile Arg Thr Leu Met Ser Ser Gly Gln Met Ala Pro Ser Ser Ser 
                805                 810                 815     


Asn Lys Ser Gly Glu Thr Asn Pro Val Gln Ile Tyr Ile Gly Leu Leu 
            820                 825                 830         


Gln Gln Leu Leu Ala Gly Val Gly Gly Leu Pro Val Met Tyr Cys Leu 
        835                 840                 845             


Leu Glu Ala Val Ser Val Tyr Pro Glu Lys Leu Ala Thr Lys Phe Val 
    850                 855                 860                 


Asp Lys Thr Glu Trp Ile Lys Ser Leu Met Asn Asn Ser Lys Glu Glu 
865                 870                 875                 880 


Met Arg Glu Leu Ala Ala Leu Phe Tyr Ser Val Val Val Ser Thr Val 
                885                 890                 895     


Ser Gly Asn Glu Leu Lys Ser Met Ile Glu Gln Leu Ile Lys Thr Thr 
            900                 905                 910         


Lys Asp Asn His Ser Pro Glu Ile Gln His Gly Ser Leu Leu Ala Leu 
        915                 920                 925             


Gly Phe Thr Val Gly Arg Tyr Leu Ala Lys Lys Lys Met Arg Met Ser 
    930                 935                 940                 


Glu Gln Gln Asp Leu Glu Arg Asn Ala Asp Thr Leu Pro Asp Gln Glu 
945                 950                 955                 960 


Glu Leu Ile Gln Ser Ala Thr Glu Thr Ile Gly Ser Phe Leu Asp Ser 
                965                 970                 975     


Thr Ser Pro Leu Leu Ala Ile Ala Ala Cys Thr Ala Leu Gly Glu Ile 
            980                 985                 990         


Gly Arg Asn Gly Pro Leu Pro Ile  Pro Ser Glu Gly Ser  Gly Phe Thr 
        995                 1000                 1005             


Lys Leu  His Leu Val Glu Ser  Leu Leu Ser Arg Ile  Pro Ser Ser 
    1010                 1015                 1020             


Lys Glu  Thr Asn Lys Met Lys  Glu Arg Ala Ile Gln  Thr Leu Gly 
    1025                 1030                 1035             


Tyr Phe  Pro Val Gly Asp Gly  Asp Phe Pro His Gln  Lys Leu Leu 
    1040                 1045                 1050             


Leu Gln  Gly Leu Met Asp Ser  Val Glu Ala Lys Gln  Ile Glu Leu 
    1055                 1060                 1065             


Gln Phe  Thr Ile Gly Glu Ala  Ile Thr Ser Ala Ala  Ile Gly Thr 
    1070                 1075                 1080             


Ser Ser  Val Ala Ala Arg Asp  Ala Trp Gln Met Thr  Glu Glu Glu 
    1085                 1090                 1095             


Tyr Thr  Pro Pro Ala Gly Ala  Lys Val Asn Asp Val  Val Pro Trp 
    1100                 1105                 1110             


Val Leu  Asp Val Ile Leu Asn  Lys His Ile Ile Ser  Pro Asn Pro 
    1115                 1120                 1125             


His Val  Arg Gln Ala Ala Cys  Ile Trp Leu Leu Ser  Leu Val Arg 
    1130                 1135                 1140             


Lys Leu  Ser Thr His Lys Glu  Val Lys Ser His Leu  Lys Glu Ile 
    1145                 1150                 1155             


Gln Ser  Ala Phe Val Ser Val  Leu Ser Glu Asn Asp  Glu Leu Ser 
    1160                 1165                 1170             


Gln Asp  Val Ala Ser Lys Gly  Leu Gly Leu Val Tyr  Glu Leu Gly 
    1175                 1180                 1185             


Asn Glu  Gln Asp Gln Gln Glu  Leu Val Ser Thr Leu  Val Glu Thr 
    1190                 1195                 1200             


Leu Met  Thr Gly Lys Arg Val  Lys His Glu Val Ser  Gly Glu Thr 
    1205                 1210                 1215             


Val Val  Phe Gln Gly Gly Ala  Leu Gly Lys Thr Pro  Asp Gly Gln 
    1220                 1225                 1230             


Gly Leu  Ser Thr Tyr Lys Glu  Leu Cys Ser Leu Ala  Ser Asp Leu 
    1235                 1240                 1245             


Ser Gln  Pro Asp Leu Val Tyr  Lys Phe Met Asn Leu  Ala Asn His 
    1250                 1255                 1260             


His Ala  Met Trp Asn Ser Arg  Lys Gly Ala Ala Phe  Gly Phe Asn 
    1265                 1270                 1275             


Val Ile  Ala Thr Arg Ala Gly  Glu Gln Leu Ala Pro  Phe Leu Pro 
    1280                 1285                 1290             


Gln Leu  Val Pro Arg Leu Tyr  Arg Tyr Gln Phe Asp  Pro Asn Leu 
    1295                 1300                 1305             


Gly Ile  Arg Gln Ala Met Thr  Ser Ile Trp Asn Ala  Leu Val Thr 
    1310                 1315                 1320             


Asp Lys  Ser Met Val Asp Lys  Tyr Leu Lys Glu Ile  Leu Gln Asp 
    1325                 1330                 1335             


Leu Val  Lys Asn Leu Thr Ser  Asn Met Trp Arg Val  Arg Glu Ser 
    1340                 1345                 1350             


Ser Cys  Leu Ala Leu Asn Asp  Leu Leu Arg Gly Arg  Pro Leu Asp 
    1355                 1360                 1365             


Asp Ile  Ile Asp Lys Leu Pro  Glu Ile Trp Glu Thr  Leu Phe Arg 
    1370                 1375                 1380             


Val Gln  Asp Asp Ile Lys Glu  Ser Val Arg Lys Ala  Ala Glu Leu 
    1385                 1390                 1395             


Ala Leu  Lys Thr Leu Ser Lys  Val Cys Val Lys Met  Cys Asp Pro 
    1400                 1405                 1410             


Ala Lys  Gly Ala Ala Gly Gln  Arg Thr Ile Ala Ala  Leu Leu Pro 
    1415                 1420                 1425             


Cys Leu  Leu Asp Lys Gly Met  Met Ser Thr Val Thr  Glu Val Arg 
    1430                 1435                 1440             


Ala Leu  Ser Ile Asn Thr Leu  Val Lys Ile Ser Lys  Ser Ala Gly 
    1445                 1450                 1455             


Ala Met  Leu Lys Pro His Ala  Pro Lys Leu Ile Pro  Ala Leu Leu 
    1460                 1465                 1470             


Glu Ser  Leu Ser Val Leu Glu  Pro Gln Val Leu Asn  Tyr Leu Ser 
    1475                 1480                 1485             


Leu Arg  Ala Thr Glu Gln Glu  Lys Ala Ala Met Asp  Ser Ala Arg 
    1490                 1495                 1500             


Leu Ser  Ala Ala Lys Ser Ser  Pro Met Met Glu Thr  Ile Asn Met 
    1505                 1510                 1515             


Cys Leu  Gln Tyr Leu Asp Val  Ser Val Leu Gly Glu  Leu Val Pro 
    1520                 1525                 1530             


Arg Leu  Cys Glu Leu Ile Arg  Ser Gly Val Gly Leu  Gly Thr Lys 
    1535                 1540                 1545             


Gly Gly  Cys Ala Ser Val Ile  Val Ser Leu Thr Thr  Gln Cys Pro 
    1550                 1555                 1560             


Gln Asp  Leu Thr Pro Tyr Ser  Gly Lys Leu Met Ser  Ala Leu Leu 
    1565                 1570                 1575             


Ser Gly  Leu Thr Asp Arg Asn  Ser Val Ile Gln Lys  Ser Cys Ala 
    1580                 1585                 1590             


Phe Ala  Met Gly His Leu Val  Arg Thr Ser Arg Asp  Ser Ser Thr 
    1595                 1600                 1605             


Glu Lys  Leu Leu Gln Lys Leu  Asn Gly Trp Tyr Met  Glu Lys Glu 
    1610                 1615                 1620             


Glu Pro  Ile Tyr Lys Thr Ser  Cys Ala Leu Thr Ile  His Ala Ile 
    1625                 1630                 1635             


Gly Arg  Tyr Ser Pro Asp Val  Leu Lys Asn His Ala  Lys Glu Val 
    1640                 1645                 1650             


Leu Pro  Leu Ala Phe Leu Gly  Met His Glu Ile Ala  Asp Glu Glu 
    1655                 1660                 1665             


Lys Ser  Glu Lys Glu Glu Cys  Asn Leu Trp Thr Glu  Val Trp Gln 
    1670                 1675                 1680             


Glu Asn  Val Pro Gly Ser Phe  Gly Gly Ile Arg Leu  Tyr Leu Gln 
    1685                 1690                 1695             


Glu Leu  Ile Thr Ile Thr Gln  Lys Ala Leu Gln Ser  Gln Ser Trp 
    1700                 1705                 1710             


Lys Met  Lys Ala Gln Gly Ala  Ile Ala Met Ala Ser  Ile Ala Lys 
    1715                 1720                 1725             


Gln Thr  Ser Ser Leu Val Pro  Pro Tyr Leu Gly Met  Ile Leu Thr 
    1730                 1735                 1740             


Ala Leu  Leu Gln Gly Leu Ala  Gly Arg Thr Trp Ala  Gly Lys Glu 
    1745                 1750                 1755             


Glu Leu  Leu Lys Ala Ile Ala  Cys Val Val Thr Ala  Cys Ser Ala 
    1760                 1765                 1770             


Glu Leu  Glu Lys Ser Val Pro  Asn Gln Pro Ser Thr  Asn Glu Ile 
    1775                 1780                 1785             


Leu Gln  Ala Val Leu Lys Glu  Cys Ser Lys Glu Asn  Val Lys Tyr 
    1790                 1795                 1800             


Lys Ile  Val Ala Ile Ser Cys  Ala Ala Asp Ile Leu  Lys Ala Thr 
    1805                 1810                 1815             


Lys Glu  Asp Arg Phe Gln Glu  Phe Ser Asn Ile Val  Ile Pro Leu 
    1820                 1825                 1830             


Ile Lys  Lys Asn Ser Leu Glu  Ser Ser Gly Val Arg  Thr Thr Lys 
    1835                 1840                 1845             


Asn Glu  Glu Glu Asn Glu Lys  Glu Lys Glu Leu Gln  Leu Glu Tyr 
    1850                 1855                 1860             


Leu Leu  Gly Ala Phe Glu Ser  Leu Gly Lys Ala Trp  Pro Arg Asn 
    1865                 1870                 1875             


Ala Glu  Thr Gln Arg Cys Tyr  Arg Gln Glu Leu Cys  Lys Leu Met 
    1880                 1885                 1890             


Cys Glu  Arg Leu Lys Leu Ser  Thr Trp Lys Val Gln  Leu Gly Val 
    1895                 1900                 1905             


Leu Gln  Ser Met Asn Ala Phe  Phe Gln Gly Leu Met  Leu Leu Glu 
    1910                 1915                 1920             


Glu Glu  His Ala Asp Pro Glu  Ala Leu Ala Glu Ile  Leu Leu Glu 
    1925                 1930                 1935             


Thr Cys  Lys Ser Ile Thr Tyr  Ser Leu Glu Asn Lys  Thr Tyr Ser 
    1940                 1945                 1950             


Ser Val  Arg Thr Glu Ala Leu  Ser Val Ile Glu Leu  Leu Leu Lys 
    1955                 1960                 1965             


Lys Leu  Glu Glu Ser Lys Gln  Trp Glu Cys Leu Thr  Ser Glu Cys 
    1970                 1975                 1980             


Arg Val  Leu Leu Ile Glu Ser  Leu Ala Thr Met Glu  Pro Asp Ser 
    1985                 1990                 1995             


Arg Pro  Glu Leu Gln Glu Lys  Ala Ala Leu Leu Lys  Lys Thr Leu 
    2000                 2005                 2010             


Glu Asn  Leu Glu 
    2015         


<210>  1128
<211>  753
<212>  PRT
<213>  Human

<400>  1128

Met Arg Pro Val Ser Val Trp Gln Trp Ser Pro Trp Gly Leu Leu Leu 
1               5                   10                  15      


Cys Leu Leu Cys Ser Ser Cys Leu Gly Ser Pro Ser Pro Ser Thr Gly 
            20                  25                  30          


Pro Glu Lys Lys Ala Gly Ser Gln Gly Leu Arg Phe Arg Leu Ala Gly 
        35                  40                  45              


Phe Pro Arg Lys Pro Tyr Glu Gly Arg Val Glu Ile Gln Arg Ala Gly 
    50                  55                  60                  


Glu Trp Gly Thr Ile Cys Asp Asp Asp Phe Thr Leu Gln Ala Ala His 
65                  70                  75                  80  


Ile Leu Cys Arg Glu Leu Gly Phe Thr Glu Ala Thr Gly Trp Thr His 
                85                  90                  95      


Ser Ala Lys Tyr Gly Pro Gly Thr Gly Arg Ile Trp Leu Asp Asn Leu 
            100                 105                 110         


Ser Cys Ser Gly Thr Glu Gln Ser Val Thr Glu Cys Ala Ser Arg Gly 
        115                 120                 125             


Trp Gly Asn Ser Asp Cys Thr His Asp Glu Asp Ala Gly Val Ile Cys 
    130                 135                 140                 


Lys Asp Gln Arg Leu Pro Gly Phe Ser Asp Ser Asn Val Ile Glu Val 
145                 150                 155                 160 


Glu His His Leu Gln Val Glu Glu Val Arg Ile Arg Pro Ala Val Gly 
                165                 170                 175     


Trp Gly Arg Arg Pro Leu Pro Val Thr Glu Gly Leu Val Glu Val Arg 
            180                 185                 190         


Leu Pro Asp Gly Trp Ser Gln Val Cys Asp Lys Gly Trp Ser Ala His 
        195                 200                 205             


Asn Ser His Val Val Cys Gly Met Leu Gly Phe Pro Ser Glu Lys Arg 
    210                 215                 220                 


Val Asn Ala Ala Phe Tyr Arg Leu Leu Ala Gln Arg Gln Gln His Ser 
225                 230                 235                 240 


Phe Gly Leu His Gly Val Ala Cys Val Gly Thr Glu Ala His Leu Ser 
                245                 250                 255     


Leu Cys Ser Leu Glu Phe Tyr Arg Ala Asn Asp Thr Ala Arg Cys Pro 
            260                 265                 270         


Gly Gly Gly Pro Ala Val Val Ser Cys Val Pro Gly Pro Val Tyr Ala 
        275                 280                 285             


Ala Ser Ser Gly Gln Lys Lys Gln Gln Gln Ser Lys Pro Gln Gly Glu 
    290                 295                 300                 


Ala Arg Val Arg Leu Lys Gly Gly Ala His Pro Gly Glu Gly Arg Val 
305                 310                 315                 320 


Glu Val Leu Lys Ala Ser Thr Trp Gly Thr Val Cys Asp Arg Lys Trp 
                325                 330                 335     


Asp Leu His Ala Ala Ser Val Val Cys Arg Glu Leu Gly Phe Gly Ser 
            340                 345                 350         


Ala Arg Glu Ala Leu Ser Gly Ala Arg Met Gly Gln Gly Met Gly Ala 
        355                 360                 365             


Ile His Leu Ser Glu Val Arg Cys Ser Gly Gln Glu Leu Ser Leu Trp 
    370                 375                 380                 


Lys Cys Pro His Lys Asn Ile Thr Ala Glu Asp Cys Ser His Ser Gln 
385                 390                 395                 400 


Asp Ala Gly Val Arg Cys Asn Leu Pro Tyr Thr Gly Ala Glu Thr Arg 
                405                 410                 415     


Ile Arg Leu Ser Gly Gly Arg Ser Gln His Glu Gly Arg Val Glu Val 
            420                 425                 430         


Gln Ile Gly Gly Pro Gly Pro Leu Arg Trp Gly Leu Ile Cys Gly Asp 
        435                 440                 445             


Asp Trp Gly Thr Leu Glu Ala Met Val Ala Cys Arg Gln Leu Gly Leu 
    450                 455                 460                 


Gly Tyr Ala Asn His Gly Leu Gln Glu Thr Trp Tyr Trp Asp Ser Gly 
465                 470                 475                 480 


Asn Ile Thr Glu Val Val Met Ser Gly Val Arg Cys Thr Gly Thr Glu 
                485                 490                 495     


Leu Ser Leu Asp Gln Cys Ala His His Gly Thr His Ile Thr Cys Lys 
            500                 505                 510         


Arg Thr Gly Thr Arg Phe Thr Ala Gly Val Ile Cys Ser Glu Thr Ala 
        515                 520                 525             


Ser Asp Leu Leu Leu His Ser Ala Leu Val Gln Glu Thr Ala Tyr Ile 
    530                 535                 540                 


Glu Asp Arg Pro Leu His Met Leu Tyr Cys Ala Ala Glu Glu Asn Cys 
545                 550                 555                 560 


Leu Ala Ser Ser Ala Arg Ser Ala Asn Trp Pro Tyr Gly His Arg Arg 
                565                 570                 575     


Leu Leu Arg Phe Ser Ser Gln Ile His Asn Leu Gly Arg Ala Asp Phe 
            580                 585                 590         


Arg Pro Lys Ala Gly Arg His Ser Trp Val Trp His Glu Cys His Gly 
        595                 600                 605             


His Tyr His Ser Met Asp Ile Phe Thr His Tyr Asp Ile Leu Thr Pro 
    610                 615                 620                 


Asn Gly Thr Lys Val Ala Glu Gly His Lys Ala Ser Phe Cys Leu Glu 
625                 630                 635                 640 


Asp Thr Glu Cys Gln Glu Asp Val Ser Lys Arg Tyr Glu Cys Ala Asn 
                645                 650                 655     


Phe Gly Glu Gln Gly Ile Thr Val Gly Cys Trp Asp Leu Tyr Arg His 
            660                 665                 670         


Asp Ile Asp Cys Gln Trp Ile Asp Ile Thr Asp Val Lys Pro Gly Asn 
        675                 680                 685             


Tyr Ile Leu Gln Val Val Ile Asn Pro Asn Phe Glu Val Ala Glu Ser 
    690                 695                 700                 


Asp Phe Thr Asn Asn Ala Met Lys Cys Asn Cys Lys Tyr Asp Gly His 
705                 710                 715                 720 


Arg Ile Trp Val His Asn Cys His Ile Gly Asp Ala Phe Ser Glu Glu 
                725                 730                 735     


Ala Asn Arg Arg Phe Glu Arg Tyr Pro Gly Gln Thr Ser Asn Gln Ile 
            740                 745                 750         


Ile 
    


<210>  1129
<211>  1827
<212>  PRT
<213>  Human

<400>  1129

Met Ala Asp Glu Arg Lys Asp Glu Ala Lys Ala Pro His Trp Thr Ser 
1               5                   10                  15      


Ala Pro Leu Thr Glu Ala Ser Ala His Ser His Pro Pro Glu Ile Lys 
            20                  25                  30          


Asp Gln Gly Gly Ala Gly Glu Gly Leu Val Arg Ser Ala Asn Gly Phe 
        35                  40                  45              


Pro Tyr Arg Glu Asp Glu Glu Gly Ala Phe Gly Glu His Gly Ser Gln 
    50                  55                  60                  


Gly Thr Tyr Ser Asn Thr Lys Glu Asn Gly Ile Asn Gly Glu Leu Thr 
65                  70                  75                  80  


Ser Ala Asp Arg Glu Thr Ala Glu Glu Val Ser Ala Arg Ile Val Gln 
                85                  90                  95      


Val Val Thr Ala Glu Ala Val Ala Val Leu Lys Gly Glu Gln Glu Lys 
            100                 105                 110         


Glu Ala Gln His Lys Asp Gln Thr Ala Ala Leu Pro Leu Ala Ala Glu 
        115                 120                 125             


Glu Thr Ala Asn Leu Pro Pro Ser Pro Pro Pro Ser Pro Ala Ser Glu 
    130                 135                 140                 


Gln Thr Val Thr Val Glu Glu Asp Leu Leu Thr Ala Ser Lys Met Glu 
145                 150                 155                 160 


Phe His Asp Gln Gln Glu Leu Thr Pro Ser Thr Ala Glu Pro Ser Asp 
                165                 170                 175     


Gln Lys Glu Lys Glu Ser Glu Lys Gln Ser Lys Pro Gly Glu Asp Leu 
            180                 185                 190         


Lys His Ala Ala Leu Val Ser Gln Pro Glu Thr Thr Lys Thr Tyr Pro 
        195                 200                 205             


Asp Lys Lys Asp Met Gln Gly Thr Glu Glu Glu Lys Ala Pro Leu Ala 
    210                 215                 220                 


Leu Phe Gly His Thr Leu Val Ala Ser Leu Glu Asp Met Lys Gln Lys 
225                 230                 235                 240 


Thr Glu Pro Ser Leu Val Val Pro Gly Ile Asp Leu Pro Lys Glu Pro 
                245                 250                 255     


Pro Thr Pro Lys Glu Gln Lys Asp Trp Phe Ile Glu Met Pro Thr Glu 
            260                 265                 270         


Ala Lys Lys Asp Glu Trp Gly Leu Val Ala Pro Ile Ser Pro Gly Pro 
        275                 280                 285             


Leu Thr Pro Met Arg Glu Lys Asp Val Phe Asp Asp Ile Pro Lys Trp 
    290                 295                 300                 


Glu Gly Lys Gln Phe Asp Ser Pro Met Pro Ser Pro Phe Gln Gly Gly 
305                 310                 315                 320 


Ser Phe Thr Leu Pro Leu Asp Val Met Lys Asn Glu Ile Val Thr Glu 
                325                 330                 335     


Thr Ser Pro Phe Ala Pro Ala Phe Leu Gln Pro Asp Asp Lys Lys Ser 
            340                 345                 350         


Leu Gln Gln Thr Ser Gly Pro Ala Thr Ala Lys Asp Ser Phe Lys Ile 
        355                 360                 365             


Glu Glu Pro His Glu Ala Lys Pro Asp Lys Met Ala Glu Ala Pro Pro 
    370                 375                 380                 


Ser Glu Ala Met Thr Leu Pro Lys Asp Ala His Ile Pro Val Val Glu 
385                 390                 395                 400 


Glu His Val Met Gly Lys Val Leu Glu Glu Glu Lys Glu Ala Ile Asn 
                405                 410                 415     


Gln Glu Thr Val Gln Gln Arg Asp Thr Phe Thr Pro Ser Gly Gln Glu 
            420                 425                 430         


Pro Ile Leu Thr Glu Lys Glu Thr Glu Leu Lys Leu Glu Glu Lys Thr 
        435                 440                 445             


Thr Ile Ser Asp Lys Glu Ala Val Pro Lys Glu Ser Lys Pro Pro Lys 
    450                 455                 460                 


Pro Ala Asp Glu Glu Ile Gly Ile Ile Gln Thr Ser Thr Glu His Thr 
465                 470                 475                 480 


Phe Ser Glu Gln Lys Asp Gln Glu Pro Thr Thr Asp Met Leu Lys Gln 
                485                 490                 495     


Asp Ser Phe Pro Val Ser Leu Glu Gln Ala Val Thr Asp Ser Ala Met 
            500                 505                 510         


Thr Ser Lys Thr Leu Glu Lys Ala Met Thr Glu Pro Ser Ala Leu Ile 
        515                 520                 525             


Glu Lys Ser Ser Ile Gln Glu Leu Phe Glu Met Arg Val Asp Asp Lys 
    530                 535                 540                 


Asp Lys Ile Glu Gly Val Gly Ala Ala Thr Ser Ala Glu Leu Asp Met 
545                 550                 555                 560 


Pro Phe Tyr Glu Asp Lys Ser Gly Met Ser Lys Tyr Phe Glu Thr Ser 
                565                 570                 575     


Ala Leu Lys Glu Glu Ala Thr Lys Ser Ile Glu Pro Gly Ser Asp Tyr 
            580                 585                 590         


Tyr Glu Leu Ser Asp Thr Arg Glu Ser Val His Glu Ser Ile Asp Thr 
        595                 600                 605             


Met Ser Pro Met His Lys Asn Gly Asp Lys Glu Phe Gln Thr Gly Lys 
    610                 615                 620                 


Glu Ser Gln Pro Ser Pro Pro Ala Gln Glu Ala Gly Tyr Ser Thr Leu 
625                 630                 635                 640 


Ala Gln Ser Tyr Pro Ser Asp Leu Pro Glu Glu Pro Ser Ser Pro Gln 
                645                 650                 655     


Glu Arg Met Phe Thr Ile Asp Pro Lys Val Tyr Gly Glu Lys Arg Asp 
            660                 665                 670         


Leu His Ser Lys Asn Lys Asp Asp Leu Thr Leu Ser Arg Ser Leu Gly 
        675                 680                 685             


Leu Gly Gly Arg Ser Ala Ile Glu Gln Arg Ser Met Ser Ile Asn Leu 
    690                 695                 700                 


Pro Met Ser Cys Leu Asp Ser Ile Ala Leu Gly Phe Asn Phe Gly Arg 
705                 710                 715                 720 


Gly His Asp Leu Ser Pro Leu Ala Ser Asp Ile Leu Thr Asn Thr Ser 
                725                 730                 735     


Gly Ser Met Asp Glu Gly Asp Asp Tyr Leu Pro Ala Thr Thr Pro Ala 
            740                 745                 750         


Leu Glu Lys Ala Pro Cys Phe Pro Val Glu Ser Lys Glu Glu Glu Gln 
        755                 760                 765             


Ile Glu Lys Val Lys Ala Thr Gly Glu Glu Ser Thr Gln Ala Glu Ile 
    770                 775                 780                 


Ser Cys Glu Ser Pro Phe Leu Ala Lys Asp Phe Tyr Lys Asn Gly Thr 
785                 790                 795                 800 


Val Met Ala Pro Asp Leu Pro Glu Met Leu Asp Leu Ala Gly Thr Arg 
                805                 810                 815     


Ser Arg Leu Ala Ser Val Ser Ala Asp Ala Glu Val Ala Arg Arg Lys 
            820                 825                 830         


Ser Val Pro Ser Glu Thr Val Val Glu Asp Ser Arg Thr Gly Leu Pro 
        835                 840                 845             


Pro Val Thr Asp Glu Asn His Val Ile Val Lys Thr Asp Ser Gln Leu 
    850                 855                 860                 


Glu Asp Leu Gly Tyr Cys Val Phe Asn Lys Tyr Thr Val Pro Leu Pro 
865                 870                 875                 880 


Ser Pro Val Gln Asp Ser Glu Asn Leu Ser Gly Glu Ser Gly Thr Phe 
                885                 890                 895     


Tyr Glu Gly Thr Asp Asp Lys Val Arg Arg Asp Leu Ala Thr Asp Leu 
            900                 905                 910         


Ser Leu Ile Glu Val Lys Leu Ala Ala Ala Gly Arg Val Lys Asp Glu 
        915                 920                 925             


Phe Ser Val Asp Lys Glu Ala Ser Ala His Ile Ser Gly Asp Lys Ser 
    930                 935                 940                 


Gly Leu Ser Lys Glu Phe Asp Gln Glu Lys Lys Ala Asn Asp Arg Leu 
945                 950                 955                 960 


Asp Thr Val Leu Glu Lys Ser Glu Glu His Ala Asp Ser Lys Glu His 
                965                 970                 975     


Ala Lys Lys Thr Glu Glu Ala Gly Asp Glu Ile Glu Thr Phe Gly Leu 
            980                 985                 990         


Gly Val Thr Tyr Glu Gln Ala Leu  Ala Lys Asp Leu Ser  Ile Pro Thr 
        995                 1000                 1005             


Asp Ala  Ser Ser Glu Lys Ala  Glu Lys Gly Leu Ser  Ser Val Pro 
    1010                 1015                 1020             


Glu Ile  Ala Glu Val Glu Pro  Ser Lys Lys Val Glu  Gln Gly Leu 
    1025                 1030                 1035             


Asp Phe  Ala Val Gln Gly Gln  Leu Asp Val Lys Ile  Ser Asp Phe 
    1040                 1045                 1050             


Gly Gln  Met Ala Ser Gly Leu  Asn Ile Asp Asp Arg  Arg Ala Thr 
    1055                 1060                 1065             


Glu Leu  Lys Leu Glu Ala Thr  Gln Asp Met Thr Pro  Ser Ser Lys 
    1070                 1075                 1080             


Ala Pro  Gln Glu Ala Asp Ala  Phe Met Gly Val Glu  Ser Gly His 
    1085                 1090                 1095             


Met Lys  Glu Gly Thr Lys Val  Ser Glu Thr Glu Val  Lys Glu Lys 
    1100                 1105                 1110             


Val Ala  Lys Pro Asp Leu Val  His Gln Glu Ala Val  Asp Lys Glu 
    1115                 1120                 1125             


Glu Ser  Tyr Glu Ser Ser Gly  Glu His Glu Ser Leu  Thr Met Glu 
    1130                 1135                 1140             


Ser Leu  Lys Ala Asp Glu Gly  Lys Lys Glu Thr Ser  Pro Glu Ser 
    1145                 1150                 1155             


Ser Leu  Ile Gln Asp Glu Ile  Ala Val Lys Leu Ser  Val Glu Ile 
    1160                 1165                 1170             


Pro Cys  Pro Pro Ala Val Ser  Glu Ala Asp Leu Ala  Thr Asp Glu 
    1175                 1180                 1185             


Arg Ala  Asp Val Gln Met Glu  Phe Ile Gln Gly Pro  Lys Glu Glu 
    1190                 1195                 1200             


Ser Lys  Glu Thr Pro Asp Ile  Ser Ile Thr Pro Ser  Asp Val Ala 
    1205                 1210                 1215             


Glu Pro  Leu His Glu Thr Ile  Val Ser Glu Pro Ala  Glu Ile Gln 
    1220                 1225                 1230             


Ser Glu  Glu Glu Glu Ile Glu  Ala Gln Gly Glu Tyr  Asp Lys Leu 
    1235                 1240                 1245             


Leu Phe  Arg Ser Asp Thr Leu  Gln Ile Thr Asp Leu  Gly Val Ser 
    1250                 1255                 1260             


Gly Ala  Arg Glu Glu Phe Val  Glu Thr Cys Pro Ser  Glu His Lys 
    1265                 1270                 1275             


Gly Val  Ile Glu Ser Val Val  Thr Ile Glu Asp Asp  Phe Ile Thr 
    1280                 1285                 1290             


Val Val  Gln Thr Thr Thr Asp  Glu Gly Glu Ser Gly  Ser His Ser 
    1295                 1300                 1305             


Val Arg  Phe Ala Ala Leu Glu  Gln Pro Glu Val Glu  Arg Arg Pro 
    1310                 1315                 1320             


Ser Pro  His Asp Glu Glu Glu  Phe Glu Val Glu Glu  Ala Ala Glu 
    1325                 1330                 1335             


Ala Gln  Ala Glu Pro Lys Asp  Gly Ser Pro Glu Ala  Pro Ala Ser 
    1340                 1345                 1350             


Pro Glu  Arg Glu Glu Val Ala  Leu Ser Glu Tyr Lys  Thr Glu Thr 
    1355                 1360                 1365             


Tyr Asp  Asp Tyr Lys Asp Glu  Thr Thr Ile Asp Asp  Ser Ile Met 
    1370                 1375                 1380             


Asp Ala  Asp Ser Leu Trp Val  Asp Thr Gln Asp Asp  Asp Arg Ser 
    1385                 1390                 1395             


Ile Met  Thr Glu Gln Leu Glu  Thr Ile Pro Lys Glu  Glu Lys Ala 
    1400                 1405                 1410             


Glu Lys  Glu Ala Arg Arg Ser  Ser Leu Glu Lys His  Arg Lys Glu 
    1415                 1420                 1425             


Lys Pro  Phe Lys Thr Gly Arg  Gly Arg Ile Ser Thr  Pro Glu Arg 
    1430                 1435                 1440             


Lys Val  Ala Lys Lys Glu Pro  Ser Thr Val Ser Arg  Asp Glu Val 
    1445                 1450                 1455             


Arg Arg  Lys Lys Ala Val Tyr  Lys Lys Ala Glu Leu  Ala Lys Lys 
    1460                 1465                 1470             


Thr Glu  Val Gln Ala His Ser  Pro Ser Arg Lys Phe  Ile Leu Lys 
    1475                 1480                 1485             


Pro Ala  Ile Lys Tyr Thr Arg  Pro Thr His Leu Ser  Cys Val Lys 
    1490                 1495                 1500             


Arg Lys  Thr Thr Ala Ala Gly  Gly Glu Ser Ala Leu  Ala Pro Ser 
    1505                 1510                 1515             


Val Phe  Lys Gln Ala Lys Asp  Lys Val Ser Asp Gly  Val Thr Lys 
    1520                 1525                 1530             


Ser Pro  Glu Lys Arg Ser Ser  Leu Pro Arg Pro Ser  Ser Ile Leu 
    1535                 1540                 1545             


Pro Pro  Arg Arg Gly Val Ser  Gly Asp Arg Asp Glu  Asn Ser Phe 
    1550                 1555                 1560             


Ser Leu  Asn Ser Ser Ile Ser  Ser Ser Ala Arg Arg  Thr Thr Arg 
    1565                 1570                 1575             


Ser Glu  Pro Ile Arg Arg Ala  Gly Lys Ser Gly Thr  Ser Thr Pro 
    1580                 1585                 1590             


Thr Thr  Pro Gly Ser Thr Ala  Ile Thr Pro Gly Thr  Pro Pro Ser 
    1595                 1600                 1605             


Tyr Ser  Ser Arg Thr Pro Gly  Thr Pro Gly Thr Pro  Ser Tyr Pro 
    1610                 1615                 1620             


Arg Thr  Pro His Thr Pro Gly  Thr Pro Lys Ser Ala  Ile Leu Val 
    1625                 1630                 1635             


Pro Ser  Glu Lys Lys Val Ala  Ile Ile Arg Thr Pro  Pro Lys Ser 
    1640                 1645                 1650             


Pro Ala  Thr Pro Lys Gln Leu  Arg Leu Ile Asn Gln  Pro Leu Pro 
    1655                 1660                 1665             


Asp Leu  Lys Asn Val Lys Ser  Lys Ile Gly Ser Thr  Asp Asn Ile 
    1670                 1675                 1680             


Lys Tyr  Gln Pro Lys Gly Gly  Gln Val Gln Ile Val  Thr Lys Lys 
    1685                 1690                 1695             


Ile Asp  Leu Ser His Val Thr  Ser Lys Cys Gly Ser  Leu Lys Asn 
    1700                 1705                 1710             


Ile Arg  His Arg Pro Gly Gly  Gly Arg Val Lys Ile  Glu Ser Val 
    1715                 1720                 1725             


Lys Leu  Asp Phe Lys Glu Lys  Ala Gln Ala Lys Val  Gly Ser Leu 
    1730                 1735                 1740             


Asp Asn  Ala His His Val Pro  Gly Gly Gly Asn Val  Lys Ile Asp 
    1745                 1750                 1755             


Ser Gln  Lys Leu Asn Phe Arg  Glu His Ala Lys Ala  Arg Val Asp 
    1760                 1765                 1770             


His Gly  Ala Glu Ile Ile Thr  Gln Ser Pro Gly Arg  Ser Ser Val 
    1775                 1780                 1785             


Ala Ser  Pro Arg Arg Leu Ser  Asn Val Ser Ser Ser  Gly Ser Ile 
    1790                 1795                 1800             


Asn Leu  Leu Glu Ser Pro Gln  Leu Ala Thr Leu Ala  Glu Asp Val 
    1805                 1810                 1815             


Thr Ala  Ala Leu Ala Lys Gln  Gly Leu 
    1820                 1825         


<210>  1130
<211>  200
<212>  PRT
<213>  Human

<400>  1130

Met Ala Gln Gln Arg Ala Leu Pro Gln Ser Lys Glu Thr Leu Leu Gln 
1               5                   10                  15      


Ser Tyr Asn Lys Arg Leu Lys Asp Asp Ile Lys Ser Ile Met Asp Asn 
            20                  25                  30          


Phe Thr Glu Ile Ile Lys Thr Ala Lys Ile Glu Asp Glu Thr Gln Val 
        35                  40                  45              


Ser Arg Ala Thr Gln Gly Glu Gln Asp Asn Tyr Glu Met His Val Arg 
    50                  55                  60                  


Ala Ala Asn Ile Val Arg Ala Gly Glu Ser Leu Met Lys Leu Val Ser 
65                  70                  75                  80  


Asp Leu Lys Gln Phe Leu Ile Leu Asn Asp Phe Pro Ser Val Asn Glu 
                85                  90                  95      


Ala Ile Asp Gln Arg Asn Gln Gln Leu Arg Thr Leu Gln Glu Glu Cys 
            100                 105                 110         


Asp Arg Lys Leu Ile Thr Leu Arg Asp Glu Ile Ser Ile Asp Leu Tyr 
        115                 120                 125             


Glu Leu Glu Glu Glu Tyr Tyr Ser Ser Ser Ser Ser Leu Cys Glu Ala 
    130                 135                 140                 


Asn Asp Leu Pro Leu Cys Glu Ala Tyr Gly Arg Leu Asp Leu Asp Thr 
145                 150                 155                 160 


Asp Ser Ala Asp Gly Leu Ser Ala Pro Leu Leu Ala Ser Pro Glu Pro 
                165                 170                 175     


Ser Ala Gly Pro Leu Gln Val Ala Ala Pro Ala His Ser His Ala Gly 
            180                 185                 190         


Gly Pro Gly Pro Thr Glu His Ala 
        195                 200 


<210>  1131
<211>  270
<212>  PRT
<213>  Human

<400>  1131

Met Ala Ala Ser Ser Ser Gly Glu Lys Glu Lys Glu Arg Leu Gly Gly 
1               5                   10                  15      


Gly Leu Gly Val Ala Gly Gly Asn Ser Thr Arg Glu Arg Leu Leu Ser 
            20                  25                  30          


Ala Leu Glu Asp Leu Glu Val Leu Ser Arg Glu Leu Ile Glu Met Leu 
        35                  40                  45              


Ala Ile Ser Arg Asn Gln Lys Leu Leu Gln Ala Gly Glu Glu Asn Gln 
    50                  55                  60                  


Val Leu Glu Leu Leu Ile His Arg Asp Gly Glu Phe Gln Glu Leu Met 
65                  70                  75                  80  


Lys Leu Ala Leu Asn Gln Gly Lys Ile His His Glu Met Gln Val Leu 
                85                  90                  95      


Glu Lys Glu Val Glu Lys Arg Asp Ser Asp Ile Gln Gln Leu Gln Lys 
            100                 105                 110         


Gln Leu Lys Glu Ala Glu Gln Ile Leu Ala Thr Ala Val Tyr Gln Ala 
        115                 120                 125             


Lys Glu Lys Leu Lys Ser Ile Glu Lys Ala Arg Lys Gly Ala Ile Ser 
    130                 135                 140                 


Ser Glu Glu Ile Ile Lys Tyr Ala His Arg Ile Ser Ala Ser Asn Ala 
145                 150                 155                 160 


Val Cys Ala Pro Leu Thr Trp Val Pro Gly Asp Pro Arg Arg Pro Tyr 
                165                 170                 175     


Pro Thr Asp Leu Glu Met Arg Ser Gly Leu Leu Gly Gln Met Asn Asn 
            180                 185                 190         


Pro Ser Thr Asn Gly Val Asn Gly His Leu Pro Gly Asp Ala Leu Ala 
        195                 200                 205             


Ala Gly Arg Leu Pro Asp Val Leu Ala Pro Gln Tyr Pro Trp Gln Ser 
    210                 215                 220                 


Asn Asp Met Ser Met Asn Met Leu Pro Pro Asn His Ser Ser Asp Phe 
225                 230                 235                 240 


Leu Leu Glu Pro Pro Gly His Asn Lys Glu Asn Glu Asp Asp Val Glu 
                245                 250                 255     


Ile Met Ser Thr Asp Ser Ser Ser Ser Ser Ser Glu Ser Asp 
            260                 265                 270 


<210>  1132
<211>  323
<212>  PRT
<213>  Human

<400>  1132

Met Ala Pro Lys Gln Asp Pro Lys Pro Lys Phe Gln Glu Gly Glu Arg 
1               5                   10                  15      


Val Leu Cys Phe His Gly Pro Leu Leu Tyr Glu Ala Lys Cys Val Lys 
            20                  25                  30          


Val Ala Ile Lys Asp Lys Gln Val Lys Tyr Phe Ile His Tyr Ser Gly 
        35                  40                  45              


Trp Asn Lys Asn Trp Asp Glu Trp Val Pro Glu Ser Arg Val Leu Lys 
    50                  55                  60                  


Tyr Val Asp Thr Asn Leu Gln Lys Gln Arg Glu Leu Gln Lys Ala Asn 
65                  70                  75                  80  


Gln Glu Gln Tyr Ala Glu Gly Lys Met Arg Gly Ala Ala Pro Gly Lys 
                85                  90                  95      


Lys Thr Ser Gly Leu Gln Gln Lys Asn Val Glu Val Lys Thr Lys Lys 
            100                 105                 110         


Asn Lys Gln Lys Thr Pro Gly Asn Gly Asp Gly Gly Ser Thr Ser Glu 
        115                 120                 125             


Thr Pro Gln Pro Pro Arg Lys Lys Arg Ala Arg Val Asp Pro Thr Val 
    130                 135                 140                 


Glu Asn Glu Glu Thr Phe Met Asn Arg Val Glu Val Lys Val Lys Ile 
145                 150                 155                 160 


Pro Glu Glu Leu Lys Pro Trp Leu Val Asp Asp Trp Asp Leu Ile Thr 
                165                 170                 175     


Arg Gln Lys Gln Leu Phe Tyr Leu Pro Ala Lys Lys Asn Val Asp Ser 
            180                 185                 190         


Ile Leu Glu Asp Tyr Ala Asn Tyr Lys Lys Ser Arg Gly Asn Thr Asp 
        195                 200                 205             


Asn Lys Glu Tyr Ala Val Asn Glu Val Val Ala Gly Ile Lys Glu Tyr 
    210                 215                 220                 


Phe Asn Val Met Leu Gly Thr Gln Leu Leu Tyr Lys Phe Glu Arg Pro 
225                 230                 235                 240 


Gln Tyr Ala Glu Ile Leu Ala Asp His Pro Asp Ala Pro Met Ser Gln 
                245                 250                 255     


Val Tyr Gly Ala Pro His Leu Leu Arg Leu Phe Val Arg Ile Gly Ala 
            260                 265                 270         


Met Leu Ala Tyr Thr Pro Leu Asp Glu Lys Ser Leu Ala Leu Leu Leu 
        275                 280                 285             


Asn Tyr Leu His Asp Phe Leu Lys Tyr Leu Ala Lys Asn Ser Ala Thr 
    290                 295                 300                 


Leu Phe Ser Ala Ser Asp Tyr Glu Val Ala Pro Pro Glu Tyr His Arg 
305                 310                 315                 320 


Lys Ala Val 
            


<210>  1133
<211>  194
<212>  PRT
<213>  Human

<400>  1133

Met Gln Ala Val Arg Asn Ala Gly Ser Arg Phe Leu Arg Ser Trp Thr 
1               5                   10                  15      


Trp Pro Gln Thr Ala Gly Arg Val Val Ala Arg Thr Pro Ala Gly Thr 
            20                  25                  30          


Ile Cys Thr Gly Ala Arg Gln Leu Gln Asp Ala Ala Ala Lys Gln Lys 
        35                  40                  45              


Val Glu Gln Asn Ala Ala Pro Ser His Thr Lys Phe Ser Ile Tyr Pro 
    50                  55                  60                  


Pro Ile Pro Gly Glu Glu Ser Ser Leu Arg Trp Ala Gly Lys Lys Phe 
65                  70                  75                  80  


Glu Glu Ile Pro Ile Ala His Ile Lys Ala Ser His Asn Asn Thr Gln 
                85                  90                  95      


Ile Gln Val Val Ser Ala Ser Asn Glu Pro Leu Ala Phe Ala Ser Cys 
            100                 105                 110         


Gly Thr Glu Gly Phe Arg Asn Ala Lys Lys Gly Thr Gly Ile Ala Ala 
        115                 120                 125             


Gln Thr Ala Gly Ile Ala Ala Ala Ala Arg Ala Lys Gln Lys Gly Val 
    130                 135                 140                 


Ile His Ile Arg Val Val Val Lys Gly Leu Gly Pro Gly Arg Leu Ser 
145                 150                 155                 160 


Ala Met His Gly Leu Ile Met Gly Gly Leu Glu Val Ile Ser Ile Thr 
                165                 170                 175     


Asp Asn Thr Pro Ile Pro His Asn Gly Cys Arg Pro Arg Lys Ala Arg 
            180                 185                 190         


Lys Leu 
        


<210>  1134
<211>  328
<212>  PRT
<213>  Human

<400>  1134

Met Asp Gly Glu Asp Ile Pro Asp Phe Ser Ser Leu Lys Glu Glu Thr 
1               5                   10                  15      


Ala Tyr Trp Lys Glu Leu Ser Leu Lys Tyr Lys Gln Ser Phe Gln Glu 
            20                  25                  30          


Ala Arg Asp Glu Leu Val Glu Phe Gln Glu Gly Ser Arg Glu Leu Glu 
        35                  40                  45              


Ala Glu Leu Glu Ala Gln Leu Val Gln Ala Glu Gln Arg Asn Arg Asp 
    50                  55                  60                  


Leu Gln Ala Asp Asn Gln Arg Leu Lys Tyr Glu Val Glu Ala Leu Lys 
65                  70                  75                  80  


Glu Lys Leu Glu His Gln Tyr Ala Gln Ser Tyr Lys Gln Val Ser Val 
                85                  90                  95      


Leu Glu Asp Asp Leu Ser Gln Thr Arg Ala Ile Lys Glu Gln Leu His 
            100                 105                 110         


Lys Tyr Val Arg Glu Leu Glu Gln Ala Asn Asp Asp Leu Glu Arg Ala 
        115                 120                 125             


Lys Arg Ala Thr Ile Val Ser Leu Glu Asp Phe Glu Gln Arg Leu Asn 
    130                 135                 140                 


Gln Ala Ile Glu Arg Asn Ala Phe Leu Glu Ser Glu Leu Asp Glu Lys 
145                 150                 155                 160 


Glu Ser Leu Leu Val Ser Val Gln Arg Leu Lys Asp Glu Ala Arg Asp 
                165                 170                 175     


Leu Arg Gln Glu Leu Ala Val Arg Glu Arg Gln Gln Glu Val Thr Arg 
            180                 185                 190         


Lys Ser Ala Pro Ser Ser Pro Thr Leu Asp Cys Glu Lys Met Asp Ser 
        195                 200                 205             


Ala Val Gln Ala Ser Leu Ser Leu Pro Ala Thr Pro Val Gly Lys Gly 
    210                 215                 220                 


Thr Glu Asn Thr Phe Pro Ser Pro Lys Ala Ile Pro Asn Gly Phe Gly 
225                 230                 235                 240 


Thr Ser Pro Leu Thr Pro Ser Ala Arg Ile Ser Ala Leu Asn Ile Val 
                245                 250                 255     


Gly Asp Leu Leu Arg Lys Val Gly Ala Leu Glu Ser Lys Leu Ala Ala 
            260                 265                 270         


Cys Arg Asn Phe Ala Lys Asp Gln Ala Ser Arg Lys Ser Tyr Ile Ser 
        275                 280                 285             


Gly Asn Val Asn Cys Gly Val Leu Asn Gly Asn Gly Thr Lys Phe Ser 
    290                 295                 300                 


Arg Ser Gly His Thr Ser Phe Phe Asp Lys Gly Gln Glu Lys Val Ile 
305                 310                 315                 320 


Phe Pro Thr Leu Phe Met Gly Gln 
                325             


<210>  1135
<211>  357
<212>  PRT
<213>  Human

<400>  1135

Met Ala Glu Leu Gln Glu Val Gln Ile Thr Glu Glu Lys Pro Leu Leu 
1               5                   10                  15      


Pro Gly Gln Thr Pro Glu Ala Ala Lys Thr His Ser Val Glu Thr Pro 
            20                  25                  30          


Tyr Gly Ser Val Thr Phe Thr Val Tyr Gly Thr Pro Lys Pro Lys Arg 
        35                  40                  45              


Pro Ala Ile Leu Thr Tyr His Asp Val Gly Leu Asn Tyr Lys Ser Cys 
    50                  55                  60                  


Phe Gln Pro Leu Phe Gln Phe Glu Asp Met Gln Glu Ile Ile Gln Asn 
65                  70                  75                  80  


Phe Val Arg Val His Val Asp Ala Pro Gly Met Glu Glu Gly Ala Pro 
                85                  90                  95      


Val Phe Pro Leu Gly Tyr Gln Tyr Pro Ser Leu Asp Gln Leu Ala Asp 
            100                 105                 110         


Met Ile Pro Cys Val Leu Gln Tyr Leu Asn Phe Ser Thr Ile Ile Gly 
        115                 120                 125             


Val Gly Val Gly Ala Gly Ala Tyr Ile Leu Ala Arg Tyr Ala Leu Asn 
    130                 135                 140                 


His Pro Asp Thr Val Glu Gly Leu Val Leu Ile Asn Ile Asp Pro Asn 
145                 150                 155                 160 


Ala Lys Gly Trp Met Asp Trp Ala Ala His Lys Leu Thr Gly Leu Thr 
                165                 170                 175     


Ser Ser Ile Pro Glu Met Ile Leu Gly His Leu Phe Ser Gln Glu Glu 
            180                 185                 190         


Leu Ser Gly Asn Ser Glu Leu Ile Gln Lys Tyr Arg Asn Ile Ile Thr 
        195                 200                 205             


His Ala Pro Asn Leu Asp Asn Ile Glu Leu Tyr Trp Asn Ser Tyr Asn 
    210                 215                 220                 


Asn Arg Arg Asp Leu Asn Phe Glu Arg Gly Gly Asp Ile Thr Leu Arg 
225                 230                 235                 240 


Cys Pro Val Met Leu Val Val Gly Asp Gln Ala Pro His Glu Asp Ala 
                245                 250                 255     


Val Val Glu Cys Asn Ser Lys Leu Asp Pro Thr Gln Thr Ser Phe Leu 
            260                 265                 270         


Lys Met Ala Asp Ser Gly Gly Gln Pro Gln Leu Thr Gln Pro Gly Lys 
        275                 280                 285             


Leu Thr Glu Ala Phe Lys Tyr Phe Leu Gln Gly Met Gly Tyr Met Ala 
    290                 295                 300                 


Ser Ser Cys Met Thr Arg Leu Ser Arg Ser Arg Thr Ala Ser Leu Thr 
305                 310                 315                 320 


Ser Ala Ala Ser Val Asp Gly Asn Arg Ser Arg Ser Arg Thr Leu Ser 
                325                 330                 335     


Gln Ser Ser Glu Ser Gly Thr Leu Ser Ser Gly Pro Pro Gly His Thr 
            340                 345                 350         


Met Glu Val Ser Cys 
        355         


<210>  1136
<211>  1020
<212>  PRT
<213>  Human

<400>  1136

Met Met Ser Phe Gly Gly Ala Asp Ala Leu Leu Gly Ala Pro Phe Ala 
1               5                   10                  15      


Pro Leu His Gly Gly Gly Ser Leu His Tyr Ala Leu Ala Arg Lys Gly 
            20                  25                  30          


Gly Ala Gly Gly Thr Arg Ser Ala Ala Gly Ser Ser Ser Gly Phe His 
        35                  40                  45              


Ser Trp Thr Arg Thr Ser Val Ser Ser Val Ser Ala Ser Pro Ser Arg 
    50                  55                  60                  


Phe Arg Gly Ala Gly Ala Ala Ser Ser Thr Asp Ser Leu Asp Thr Leu 
65                  70                  75                  80  


Ser Asn Gly Pro Glu Gly Cys Met Val Ala Val Ala Thr Ser Arg Ser 
                85                  90                  95      


Glu Lys Glu Gln Leu Gln Ala Leu Asn Asp Arg Phe Ala Gly Tyr Ile 
            100                 105                 110         


Asp Lys Val Arg Gln Leu Glu Ala His Asn Arg Ser Leu Glu Gly Glu 
        115                 120                 125             


Ala Ala Ala Leu Arg Gln Gln Gln Ala Gly Arg Ser Ala Met Gly Glu 
    130                 135                 140                 


Leu Tyr Glu Arg Glu Val Arg Glu Met Arg Gly Ala Val Leu Arg Leu 
145                 150                 155                 160 


Gly Ala Ala Arg Gly Gln Leu Arg Leu Glu Gln Glu His Leu Leu Glu 
                165                 170                 175     


Asp Ile Ala His Val Arg Gln Arg Leu Asp Asp Glu Ala Arg Gln Arg 
            180                 185                 190         


Glu Glu Ala Glu Ala Ala Ala Arg Ala Leu Ala Arg Phe Ala Gln Glu 
        195                 200                 205             


Ala Glu Ala Ala Arg Val Asp Leu Gln Lys Lys Ala Gln Ala Leu Gln 
    210                 215                 220                 


Glu Glu Cys Gly Tyr Leu Arg Arg His His Gln Glu Glu Val Gly Glu 
225                 230                 235                 240 


Leu Leu Gly Gln Ile Gln Gly Ser Gly Ala Ala Gln Ala Gln Met Gln 
                245                 250                 255     


Ala Glu Thr Arg Asp Ala Leu Lys Cys Asp Val Thr Ser Ala Leu Arg 
            260                 265                 270         


Glu Ile Arg Ala Gln Leu Glu Gly His Ala Val Gln Ser Thr Leu Gln 
        275                 280                 285             


Ser Glu Glu Trp Phe Arg Val Arg Leu Asp Arg Leu Ser Glu Ala Ala 
    290                 295                 300                 


Lys Val Asn Thr Asp Ala Met Arg Ser Ala Gln Glu Glu Ile Thr Glu 
305                 310                 315                 320 


Tyr Arg Arg Gln Leu Gln Ala Arg Thr Thr Glu Leu Glu Ala Leu Lys 
                325                 330                 335     


Ser Thr Lys Asp Ser Leu Glu Arg Gln Arg Ser Glu Leu Glu Asp Arg 
            340                 345                 350         


His Gln Ala Asp Ile Ala Ser Tyr Gln Glu Ala Ile Gln Gln Leu Asp 
        355                 360                 365             


Ala Glu Leu Arg Asn Thr Lys Trp Glu Met Ala Ala Gln Leu Arg Glu 
    370                 375                 380                 


Tyr Gln Asp Leu Leu Asn Val Lys Met Ala Leu Asp Ile Glu Ile Ala 
385                 390                 395                 400 


Ala Tyr Arg Lys Leu Leu Glu Gly Glu Glu Cys Arg Ile Gly Phe Gly 
                405                 410                 415     


Pro Ile Pro Phe Ser Leu Pro Glu Gly Leu Pro Lys Ile Pro Ser Val 
            420                 425                 430         


Ser Thr His Ile Lys Val Lys Ser Glu Glu Lys Ile Lys Val Val Glu 
        435                 440                 445             


Lys Ser Glu Lys Glu Thr Val Ile Val Glu Glu Gln Thr Glu Glu Thr 
    450                 455                 460                 


Gln Val Thr Glu Glu Val Thr Glu Glu Glu Glu Lys Glu Ala Lys Glu 
465                 470                 475                 480 


Glu Glu Gly Lys Glu Glu Glu Gly Gly Glu Glu Glu Glu Ala Glu Gly 
                485                 490                 495     


Gly Glu Glu Glu Thr Lys Ser Pro Pro Ala Glu Glu Ala Ala Ser Pro 
            500                 505                 510         


Glu Lys Glu Ala Lys Ser Pro Val Lys Glu Glu Ala Lys Ser Pro Ala 
        515                 520                 525             


Glu Ala Lys Ser Pro Glu Lys Glu Glu Ala Lys Ser Pro Ala Glu Val 
    530                 535                 540                 


Lys Ser Pro Glu Lys Ala Lys Ser Pro Ala Lys Glu Glu Ala Lys Ser 
545                 550                 555                 560 


Pro Pro Glu Ala Lys Ser Pro Glu Lys Glu Glu Ala Lys Ser Pro Ala 
                565                 570                 575     


Glu Val Lys Ser Pro Glu Lys Ala Lys Ser Pro Ala Lys Glu Glu Ala 
            580                 585                 590         


Lys Ser Pro Ala Glu Ala Lys Ser Pro Glu Lys Ala Lys Ser Pro Val 
        595                 600                 605             


Lys Glu Glu Ala Lys Ser Pro Ala Glu Ala Lys Ser Pro Val Lys Glu 
    610                 615                 620                 


Glu Ala Lys Ser Pro Ala Glu Val Lys Ser Pro Glu Lys Ala Lys Ser 
625                 630                 635                 640 


Pro Thr Lys Glu Glu Ala Lys Ser Pro Glu Lys Ala Lys Ser Pro Glu 
                645                 650                 655     


Lys Glu Glu Ala Lys Ser Pro Glu Lys Ala Lys Ser Pro Val Lys Ala 
            660                 665                 670         


Glu Ala Lys Ser Pro Glu Lys Ala Lys Ser Pro Val Lys Ala Glu Ala 
        675                 680                 685             


Lys Ser Pro Glu Lys Ala Lys Ser Pro Val Lys Glu Glu Ala Lys Ser 
    690                 695                 700                 


Pro Glu Lys Ala Lys Ser Pro Val Lys Glu Glu Ala Lys Ser Pro Glu 
705                 710                 715                 720 


Lys Ala Lys Ser Pro Val Lys Glu Glu Ala Lys Thr Pro Glu Lys Ala 
                725                 730                 735     


Lys Ser Pro Val Lys Glu Glu Ala Lys Ser Pro Glu Lys Ala Lys Ser 
            740                 745                 750         


Pro Glu Lys Ala Lys Thr Leu Asp Val Lys Ser Pro Glu Ala Lys Thr 
        755                 760                 765             


Pro Ala Lys Glu Glu Ala Arg Ser Pro Ala Asp Lys Phe Pro Glu Lys 
    770                 775                 780                 


Ala Lys Ser Pro Val Lys Glu Glu Val Lys Ser Pro Glu Lys Ala Lys 
785                 790                 795                 800 


Ser Pro Leu Lys Glu Asp Ala Lys Ala Pro Glu Lys Glu Ile Pro Lys 
                805                 810                 815     


Lys Glu Glu Val Lys Ser Pro Val Lys Glu Glu Glu Lys Pro Gln Glu 
            820                 825                 830         


Val Lys Val Lys Glu Pro Pro Lys Lys Ala Glu Glu Glu Lys Ala Pro 
        835                 840                 845             


Ala Thr Pro Lys Thr Glu Glu Lys Lys Asp Ser Lys Lys Glu Glu Ala 
    850                 855                 860                 


Pro Lys Lys Glu Ala Pro Lys Pro Lys Val Glu Glu Lys Lys Glu Pro 
865                 870                 875                 880 


Ala Val Glu Lys Pro Lys Glu Ser Lys Val Glu Ala Lys Lys Glu Glu 
                885                 890                 895     


Ala Glu Asp Lys Lys Lys Val Pro Thr Pro Glu Lys Glu Ala Pro Ala 
            900                 905                 910         


Lys Val Glu Val Lys Glu Asp Ala Lys Pro Lys Glu Lys Thr Glu Val 
        915                 920                 925             


Ala Lys Lys Glu Pro Asp Asp Ala Lys Ala Lys Glu Pro Ser Lys Pro 
    930                 935                 940                 


Ala Glu Lys Lys Glu Ala Ala Pro Glu Lys Lys Asp Thr Lys Glu Glu 
945                 950                 955                 960 


Lys Ala Lys Lys Pro Glu Glu Lys Pro Lys Thr Glu Ala Lys Ala Lys 
                965                 970                 975     


Glu Asp Asp Lys Thr Leu Ser Lys Glu Pro Ser Lys Pro Lys Ala Glu 
            980                 985                 990         


Lys Ala Glu Lys Ser Ser Ser Thr  Asp Gln Lys Asp Ser  Lys Pro Pro 
        995                 1000                 1005             


Glu Lys  Ala Thr Glu Asp Lys  Ala Ala Lys Gly Lys  
    1010                 1015                 1020 


<210>  1137
<211>  1271
<212>  PRT
<213>  Human

<400>  1137

Met Glu Ala Leu Arg Asn Pro Met Pro Leu Gly Ser Ser Glu Glu Ala 
1               5                   10                  15      


Leu Gly Asp Leu Ala Cys Ser Ser Leu Thr Gly Ala Ser Arg Asp Leu 
            20                  25                  30          


Gly Thr Gly Ala Val Ala Ser Gly Thr Gln Glu Glu Thr Ser Gly Pro 
        35                  40                  45              


Arg Gly Asp Pro Gln Gln Thr Pro Ser Leu Glu Lys Glu Arg His Thr 
    50                  55                  60                  


Pro Ser Arg Thr Gly Pro Gly Ala Ala Gly Arg Thr Leu Pro Arg Arg 
65                  70                  75                  80  


Ser Arg Ser Trp Glu Arg Ala Pro Arg Ser Ser Arg Gly Ala Gln Ala 
                85                  90                  95      


Ala Ala Cys His Thr Ser His His Ser Ala Gly Ser Arg Pro Gly Gly 
            100                 105                 110         


His Leu Gly Gly Gln Ala Val Gly Thr Pro Asn Cys Val Pro Val Glu 
        115                 120                 125             


Gly Pro Gly Cys Thr Lys Glu Glu Asp Val Leu Ala Ser Ser Ala Cys 
    130                 135                 140                 


Val Ser Thr Asp Gly Gly Ser Leu His Cys His Asn Pro Ser Gly Pro 
145                 150                 155                 160 


Ser Asp Val Pro Ala Arg Gln Pro His Pro Glu Gln Glu Gly Trp Pro 
                165                 170                 175     


Pro Gly Thr Gly Asp Phe Pro Ser Gln Val Pro Lys Gln Val Leu Asp 
            180                 185                 190         


Val Ser Gln Glu Leu Leu Gln Ser Gly Val Val Thr Leu Pro Gly Thr 
        195                 200                 205             


Arg Asp Arg His Gly Arg Ala Val Val Gln Val Arg Thr Arg Ser Leu 
    210                 215                 220                 


Leu Trp Thr Arg Glu His Ser Ser Cys Ala Glu Leu Thr Arg Leu Leu 
225                 230                 235                 240 


Leu Tyr Phe His Ser Ile Pro Arg Lys Glu Val Arg Asp Leu Gly Leu 
                245                 250                 255     


Val Val Leu Val Asp Ala Arg Arg Ser Pro Ala Ala Pro Ala Val Ser 
            260                 265                 270         


Gln Ala Leu Ser Gly Leu Gln Asn Asn Thr Ser Pro Ile Ile His Ser 
        275                 280                 285             


Ile Leu Leu Leu Val Asp Lys Glu Ser Ala Phe Arg Pro Asp Lys Asp 
    290                 295                 300                 


Ala Ile Ile Gln Cys Glu Val Val Ser Ser Leu Lys Ala Val His Lys 
305                 310                 315                 320 


Phe Val Asp Ser Cys Gln Leu Thr Ala Asp Leu Asp Gly Ser Phe Pro 
                325                 330                 335     


Tyr Ser His Gly Asp Trp Ile Cys Phe Arg Gln Arg Leu Glu His Phe 
            340                 345                 350         


Ala Ala Asn Cys Glu Glu Ala Ile Ile Phe Leu Gln Asn Ser Phe Cys 
        355                 360                 365             


Ser Leu Asn Thr His Arg Thr Pro Arg Thr Ala Gln Glu Val Ala Glu 
    370                 375                 380                 


Leu Ile Asp Gln His Glu Thr Met Met Lys Leu Val Leu Glu Asp Pro 
385                 390                 395                 400 


Leu Leu Val Ser Leu Arg Leu Glu Gly Gly Thr Val Leu Ala Arg Leu 
                405                 410                 415     


Arg Arg Glu Glu Leu Gly Thr Glu Asp Ser Arg Asp Thr Leu Glu Ala 
            420                 425                 430         


Ala Thr Ser Leu Tyr Asp Arg Val Asp Glu Glu Val His Arg Leu Val 
        435                 440                 445             


Leu Thr Ser Asn Asn Arg Leu Gln Gln Leu Glu His Leu Arg Glu Leu 
    450                 455                 460                 


Ala Ser Leu Leu Glu Gly Asn Asp Gln Gln Ser Cys Gln Lys Gly Leu 
465                 470                 475                 480 


Gln Leu Ala Lys Glu Asn Pro Gln Arg Thr Glu Glu Met Val Gln Asp 
                485                 490                 495     


Phe Arg Arg Gly Leu Ser Ala Val Val Ser Gln Ala Glu Cys Arg Glu 
            500                 505                 510         


Gly Glu Leu Ala Arg Trp Thr Arg Ser Ser Glu Leu Cys Glu Thr Val 
        515                 520                 525             


Ser Ser Trp Met Gly Pro Leu Asp Pro Glu Ala Cys Pro Ser Ser Pro 
    530                 535                 540                 


Val Ala Glu Cys Leu Arg Ser Cys His Gln Glu Ala Thr Ser Val Ala 
545                 550                 555                 560 


Ala Glu Ala Phe Pro Gly Ala Gly Val Ala Val Leu Lys Pro His Ala 
                565                 570                 575     


Leu Gly Lys Pro Trp Ala Ser Gln Gln Asp Leu Trp Leu Gln Tyr Pro 
            580                 585                 590         


Gln Thr Arg Leu Arg Leu Glu Glu Ala Leu Ser Glu Ala Ala Pro Asp 
        595                 600                 605             


Pro Ser Leu Pro Pro Leu Ala Gln Ser Pro Pro Lys His Glu Arg Ala 
    610                 615                 620                 


Gln Glu Ala Met Arg Arg His Gln Lys Pro Pro Ser Phe Pro Ser Thr 
625                 630                 635                 640 


Asp Ser Gly Gly Gly Ala Trp Glu Pro Ala Gln Pro Leu Ser Gly Leu 
                645                 650                 655     


Pro Gly Arg Ala Leu Leu Cys Gly Gln Asp Gly Glu Thr Leu Arg Pro 
            660                 665                 670         


Gly Leu Cys Ala Leu Trp Asp Pro Leu Ser Leu Leu Arg Gly Leu Pro 
        675                 680                 685             


Gly Ala Gly Ala Thr Thr Ala His Leu Glu Asp Ser Ser Ala Cys Ser 
    690                 695                 700                 


Ser Glu Pro Thr Gln Thr Leu Ala Ser Arg Pro Arg Lys His Pro Gln 
705                 710                 715                 720 


Lys Lys Met Ile Lys Lys Thr Gln Ser Phe Glu Ile Pro Gln Pro Asp 
                725                 730                 735     


Ser Gly Pro Arg Asp Ser Cys Gln Pro Asp His Thr Ser Val Phe Ser 
            740                 745                 750         


Lys Gly Leu Glu Val Thr Ser Thr Val Ala Thr Glu Lys Lys Leu Pro 
        755                 760                 765             


Leu Trp Gln His Ala Arg Ser Pro Pro Val Thr Gln Ser Arg Ser Leu 
    770                 775                 780                 


Ser Ser Pro Ser Gly Leu His Pro Ala Glu Glu Asp Gly Arg Gln Gln 
785                 790                 795                 800 


Val Gly Ser Ser Arg Leu Arg His Ile Met Ala Glu Met Ile Ala Thr 
                805                 810                 815     


Glu Arg Glu Tyr Ile Arg Cys Leu Gly Tyr Val Ile Asp Asn Tyr Phe 
            820                 825                 830         


Pro Glu Met Glu Arg Met Asp Leu Pro Gln Gly Leu Arg Gly Lys His 
        835                 840                 845             


His Val Ile Phe Gly Asn Leu Glu Lys Leu His Asp Phe His Gln Gln 
    850                 855                 860                 


His Phe Leu Arg Glu Leu Glu Arg Cys Gln His Cys Pro Leu Ala Val 
865                 870                 875                 880 


Gly Arg Ser Phe Leu Arg His Glu Glu Gln Phe Gly Met Tyr Val Ile 
                885                 890                 895     


Tyr Ser Lys Asn Lys Pro Gln Ser Asp Ala Leu Leu Ser Ser His Gly 
            900                 905                 910         


Asn Ala Phe Phe Lys Asp Lys Gln Arg Glu Leu Gly Asp Lys Met Asp 
        915                 920                 925             


Leu Ala Ser Tyr Leu Leu Arg Pro Val Gln Arg Val Ala Lys Tyr Ala 
    930                 935                 940                 


Leu Leu Leu Gln Asp Leu Leu Lys Glu Ala Ser Cys Gly Leu Ala Gln 
945                 950                 955                 960 


Gly Gln Glu Leu Gly Glu Leu Arg Ala Ala Glu Val Val Val Cys Phe 
                965                 970                 975     


Gln Leu Arg His Gly Asn Asp Leu Leu Ala Met Asp Ala Ile Arg Gly 
            980                 985                 990         


Cys Asp Val Asn Leu Lys Glu Gln  Gly Gln Leu Arg Cys  Arg Asp Glu 
        995                 1000                 1005             


Phe Ile  Val Cys Cys Gly Arg  Lys Lys Tyr Leu Arg  His Val Phe 
    1010                 1015                 1020             


Leu Phe  Glu Asp Leu Ile Leu  Phe Ser Lys Thr Gln  Lys Val Glu 
    1025                 1030                 1035             


Gly Ser  His Asp Val Tyr Leu  Tyr Lys Gln Ser Phe  Lys Thr Ala 
    1040                 1045                 1050             


Glu Ile  Gly Met Thr Glu Asn  Val Gly Asp Ser Gly  Leu Arg Phe 
    1055                 1060                 1065             


Glu Ile  Trp Phe Arg Arg Arg  Arg Lys Ser Gln Asp  Thr Tyr Ile 
    1070                 1075                 1080             


Leu Gln  Ala Ser Ser Ala Glu  Val Lys Ser Ala Trp  Thr Asp Val 
    1085                 1090                 1095             


Ile Gly  Arg Ile Leu Trp Arg  Gln Ala Leu Lys Ser  Arg Glu Leu 
    1100                 1105                 1110             


Arg Ile  Gln Glu Met Ala Ser  Met Gly Ile Gly Asn  Gln Pro Phe 
    1115                 1120                 1125             


Met Asp  Val Lys Pro Arg Asp  Arg Thr Pro Asp Cys  Ala Val Ile 
    1130                 1135                 1140             


Ser Asp  Arg Ala Pro Lys Cys  Ala Val Met Ser Asp  Arg Val Pro 
    1145                 1150                 1155             


Asp Ser  Ile Val Lys Gly Thr  Glu Ser Gln Met Arg  Gly Ser Thr 
    1160                 1165                 1170             


Ala Val  Ser Ser Ser Asp His  Ala Ala Pro Phe Lys  Arg Pro His 
    1175                 1180                 1185             


Ser Thr  Ile Ser Asp Ser Ser  Thr Ser Ser Ser Ser  Ser Gln Ser 
    1190                 1195                 1200             


Ser Ser  Ile Leu Gly Ser Leu  Gly Leu Leu Val Ser  Ser Ser Pro 
    1205                 1210                 1215             


Ala His  Pro Gly Leu Trp Ser  Pro Ala His Ser Pro  Trp Ser Ser 
    1220                 1225                 1230             


Asp Ile  Arg Ala Cys Val Glu  Glu Asp Glu Pro Glu  Pro Glu Leu 
    1235                 1240                 1245             


Glu Thr  Gly Thr Gln Ala Ala  Val Cys Glu Gly Ala  Pro Ala Val 
    1250                 1255                 1260             


Leu Leu  Ser Arg Thr Arg Gln  Ala 
    1265                 1270     


<210>  1138
<211>  677
<212>  PRT
<213>  Human

<400>  1138

Met Asp Asp Pro Asp Cys Asp Ser Thr Trp Glu Glu Asp Glu Glu Asp 
1               5                   10                  15      


Ala Glu Asp Ala Glu Asp Glu Asp Cys Glu Asp Gly Glu Ala Ala Gly 
            20                  25                  30          


Ala Arg Asp Ala Asp Ala Gly Asp Glu Asp Glu Glu Ser Glu Glu Pro 
        35                  40                  45              


Arg Ala Ala Arg Pro Ser Ser Phe Gln Ser Arg Met Thr Gly Ser Arg 
    50                  55                  60                  


Asn Trp Arg Ala Thr Arg Asp Met Cys Arg Tyr Arg His Asn Tyr Pro 
65                  70                  75                  80  


Asp Leu Val Glu Arg Asp Cys Asn Gly Asp Thr Pro Asn Leu Ser Phe 
                85                  90                  95      


Tyr Arg Asn Glu Ile Arg Phe Leu Pro Asn Gly Cys Phe Ile Glu Asp 
            100                 105                 110         


Ile Leu Gln Asn Trp Thr Asp Asn Tyr Asp Leu Leu Glu Asp Asn His 
        115                 120                 125             


Ser Tyr Ile Gln Trp Leu Phe Pro Leu Arg Glu Pro Gly Val Asn Trp 
    130                 135                 140                 


His Ala Lys Pro Leu Thr Leu Arg Glu Val Glu Val Phe Lys Ser Ser 
145                 150                 155                 160 


Gln Glu Ile Gln Glu Arg Leu Val Arg Ala Tyr Glu Leu Met Leu Gly 
                165                 170                 175     


Phe Tyr Gly Ile Arg Leu Glu Asp Arg Gly Thr Gly Thr Val Gly Arg 
            180                 185                 190         


Ala Gln Asn Tyr Gln Lys Arg Phe Gln Asn Leu Asn Trp Arg Ser His 
        195                 200                 205             


Asn Asn Leu Arg Ile Thr Arg Ile Leu Lys Ser Leu Gly Glu Leu Gly 
    210                 215                 220                 


Leu Glu His Phe Gln Ala Pro Leu Val Arg Phe Phe Leu Glu Glu Thr 
225                 230                 235                 240 


Leu Val Arg Arg Glu Leu Pro Gly Val Arg Gln Ser Ala Leu Asp Tyr 
                245                 250                 255     


Phe Met Phe Ala Val Arg Cys Arg His Gln Arg Arg Gln Leu Val His 
            260                 265                 270         


Phe Ala Trp Glu His Phe Arg Pro Arg Cys Lys Phe Val Trp Gly Pro 
        275                 280                 285             


Gln Asp Lys Leu Arg Arg Phe Lys Pro Ser Ser Leu Pro His Pro Leu 
    290                 295                 300                 


Glu Gly Ser Arg Lys Val Glu Glu Glu Gly Ser Pro Gly Asp Pro Asp 
305                 310                 315                 320 


His Glu Ala Ser Thr Gln Gly Arg Thr Cys Gly Pro Glu His Ser Lys 
                325                 330                 335     


Gly Gly Gly Arg Val Asp Glu Gly Pro Gln Pro Arg Ser Val Glu Pro 
            340                 345                 350         


Gln Asp Ala Gly Pro Leu Glu Arg Ser Gln Gly Asp Glu Ala Gly Gly 
        355                 360                 365             


His Gly Glu Asp Arg Pro Glu Pro Leu Ser Pro Lys Glu Ser Lys Lys 
    370                 375                 380                 


Arg Lys Leu Glu Leu Ser Arg Arg Glu Gln Pro Pro Thr Glu Pro Gly 
385                 390                 395                 400 


Pro Gln Ser Ala Ser Glu Val Glu Lys Ile Ala Leu Asn Leu Glu Gly 
                405                 410                 415     


Cys Ala Leu Ser Gln Gly Ser Leu Arg Thr Gly Thr Gln Glu Val Gly 
            420                 425                 430         


Gly Gln Asp Pro Gly Glu Ala Val Gln Pro Cys Arg Gln Pro Leu Gly 
        435                 440                 445             


Ala Arg Val Ala Asp Lys Val Arg Lys Arg Arg Lys Val Asp Glu Gly 
    450                 455                 460                 


Ala Gly Asp Ser Ala Ala Val Ala Ser Gly Gly Ala Gln Thr Leu Ala 
465                 470                 475                 480 


Leu Ala Gly Ser Pro Ala Pro Ser Gly His Pro Lys Ala Gly His Ser 
                485                 490                 495     


Glu Asn Gly Val Glu Glu Asp Thr Glu Gly Arg Thr Gly Pro Lys Glu 
            500                 505                 510         


Gly Thr Pro Gly Ser Pro Ser Glu Thr Pro Gly Pro Ser Pro Ala Gly 
        515                 520                 525             


Pro Ala Gly Asp Glu Pro Ala Glu Ser Pro Ser Glu Thr Pro Gly Pro 
    530                 535                 540                 


Arg Pro Ala Gly Pro Ala Gly Asp Glu Pro Ala Glu Ser Pro Ser Glu 
545                 550                 555                 560 


Thr Pro Gly Pro Arg Pro Ala Gly Pro Ala Gly Asp Glu Pro Ala Glu 
                565                 570                 575     


Ser Pro Ser Glu Thr Pro Gly Pro Ser Pro Ala Gly Pro Thr Arg Asp 
            580                 585                 590         


Glu Pro Ala Glu Ser Pro Ser Glu Thr Pro Gly Pro Arg Pro Ala Gly 
        595                 600                 605             


Pro Ala Gly Asp Glu Pro Ala Glu Ser Pro Ser Glu Thr Pro Gly Pro 
    610                 615                 620                 


Arg Pro Ala Gly Pro Ala Gly Asp Glu Pro Ala Glu Ser Pro Ser Glu 
625                 630                 635                 640 


Thr Pro Gly Pro Ser Pro Ala Gly Pro Thr Arg Asp Glu Pro Ala Lys 
                645                 650                 655     


Ala Gly Glu Ala Ala Glu Leu Gln Asp Ala Glu Val Glu Ser Ser Ala 
            660                 665                 670         


Lys Ser Gly Lys Pro 
        675         


<210>  1139
<211>  798
<212>  PRT
<213>  Human

<400>  1139

Met Glu Ile Arg Gly Ala Leu Asp Leu Arg Lys Arg Gln Val Leu Ile 
1               5                   10                  15      


Phe Leu Val Leu Leu Gly Leu Ser Arg Ala Gly Thr Glu Ser Ala His 
            20                  25                  30          


Tyr Ser Val Ala Glu Glu Thr Glu Ile Gly Ser Phe Val Ala Asn Leu 
        35                  40                  45              


Ala Arg Asp Leu Gly Leu Gly Val Glu Glu Leu Ser Ser Arg Glu Ala 
    50                  55                  60                  


Arg Val Val Ser Asp Asp Asn Lys Lys Tyr Leu His Leu Asp Leu Leu 
65                  70                  75                  80  


Thr Gly Asn Leu Leu Leu Asn Glu Lys Leu Asp Arg Asp Glu Leu Cys 
                85                  90                  95      


Gly Ser Thr Glu Pro Cys Val Leu His Phe Gln Val Val Leu Glu Asn 
            100                 105                 110         


Pro Leu Gln Phe Phe Arg Phe Glu Leu Cys Val Lys Asp Ile Asn Asp 
        115                 120                 125             


His Ser Pro Thr Phe Leu Asp Lys Glu Ile Leu Ile Lys Ile Ser Glu 
    130                 135                 140                 


Gly Thr Thr Val Gly Ala Thr Phe Leu Met Glu Ser Ala Gln Asp Leu 
145                 150                 155                 160 


Asp Val Gly Ser Asn Ser Leu Gln Asn Tyr Thr Ile Ser Pro Asn Ser 
                165                 170                 175     


His Phe Tyr Ile Lys Ile Pro Asp Ser Ser Asp Arg Lys Ile Tyr Pro 
            180                 185                 190         


Glu Leu Val Leu Asp Arg Ala Leu Asp Tyr Glu Gln Glu Ala Glu Leu 
        195                 200                 205             


Arg Leu Thr Leu Thr Ala Val Asp Gly Gly Ser Pro Pro Lys Ser Gly 
    210                 215                 220                 


Thr Thr Leu Val Leu Ile Lys Val Leu Asp Ile Asn Asp Asn Ala Pro 
225                 230                 235                 240 


Glu Phe Pro Gln Ser Leu Tyr Glu Val Gln Val Pro Glu Asp Arg Pro 
                245                 250                 255     


Leu Gly Ser Trp Ile Ala Thr Ile Ser Ala Lys Asp Leu Asp Ala Gly 
            260                 265                 270         


Asn Tyr Gly Lys Ile Ser Tyr Thr Phe Phe His Ala Ser Glu Asp Ile 
        275                 280                 285             


Arg Lys Thr Phe Glu Ile Asn Pro Ile Ser Gly Glu Val Asn Leu Arg 
    290                 295                 300                 


Ser Pro Leu Asp Phe Glu Val Ile Gln Ser Tyr Thr Ile Asn Ile Gln 
305                 310                 315                 320 


Ala Thr Asp Gly Gly Gly Leu Ser Gly Lys Cys Thr Leu Leu Val Lys 
                325                 330                 335     


Val Met Asp Ile Asn Asp Asn Pro Pro Glu Val Thr Ile Ser Ser Ile 
            340                 345                 350         


Thr Lys Arg Ile Pro Glu Asn Ala Ser Glu Thr Leu Val Ala Leu Phe 
        355                 360                 365             


Ser Ile Leu Asp Gln Asp Ser Gly Asp Asn Gly Arg Met Ile Cys Ser 
    370                 375                 380                 


Ile Gln Asp Asn Leu Pro Phe Phe Leu Lys Pro Thr Phe Lys Asn Phe 
385                 390                 395                 400 


Phe Thr Leu Val Ser Glu Lys Ala Leu Asp Arg Glu Ser Gln Ala Glu 
                405                 410                 415     


Tyr Asn Ile Thr Ile Thr Val Thr Asp Leu Gly Thr Pro Arg Leu Lys 
            420                 425                 430         


Thr Glu Tyr Asn Ile Thr Val Leu Leu Ser Asp Val Asn Asp Asn Ala 
        435                 440                 445             


Pro Thr Phe Thr Gln Thr Ser Tyr Thr Leu Phe Val Arg Glu Asn Asn 
    450                 455                 460                 


Ser Pro Ala Leu His Ile Gly Ser Val Ser Ala Thr Asp Arg Asp Ser 
465                 470                 475                 480 


Gly Thr Asn Ala Gln Val Asn Tyr Ser Leu Leu Pro Pro Gln Asp Arg 
                485                 490                 495     


His Leu Pro Leu Ala Ser Leu Val Ser Ile Asn Ala Asp Asn Gly His 
            500                 505                 510         


Leu Phe Ala Leu Arg Ser Leu Asp Tyr Glu Ala Leu Gln Glu Phe Glu 
        515                 520                 525             


Phe Arg Val Gly Ala Thr Asp Arg Gly Ser Pro Ala Leu Ser Ser Glu 
    530                 535                 540                 


Ala Leu Val Arg Val Leu Val Leu Asp Ala Asn Asp Asn Ser Pro Phe 
545                 550                 555                 560 


Val Leu Tyr Pro Leu Gln Asn Gly Ser Ala Pro Cys Thr Glu Leu Val 
                565                 570                 575     


Pro Arg Ala Ala Glu Pro Gly Tyr Leu Val Thr Lys Val Val Ala Val 
            580                 585                 590         


Asp Gly Asp Ser Gly Gln Asn Ala Trp Leu Ser Tyr Gln Leu Leu Lys 
        595                 600                 605             


Ala Thr Glu Pro Gly Leu Phe Gly Val Trp Ala His Asn Gly Glu Val 
    610                 615                 620                 


Arg Thr Ala Arg Leu Leu Ser Glu Arg Asp Ala Ala Lys His Arg Leu 
625                 630                 635                 640 


Val Val Leu Val Lys Asp Asn Gly Glu Pro Pro Arg Ser Ala Thr Ala 
                645                 650                 655     


Thr Leu His Val Leu Leu Val Asp Gly Phe Ser Gln Pro Tyr Leu Pro 
            660                 665                 670         


Leu Pro Glu Ala Ala Pro Ala Gln Ala Gln Ala Asp Ser Leu Thr Val 
        675                 680                 685             


Tyr Leu Val Val Ala Leu Ala Ser Val Ser Ser Leu Phe Leu Phe Ser 
    690                 695                 700                 


Val Leu Leu Phe Val Ala Val Arg Leu Cys Arg Arg Ser Arg Ala Ala 
705                 710                 715                 720 


Ser Val Gly Arg Cys Ser Val Pro Glu Gly Pro Phe Pro Gly His Leu 
                725                 730                 735     


Val Asp Val Ser Gly Thr Gly Thr Leu Ser Gln Ser Tyr Gln Tyr Glu 
            740                 745                 750         


Val Cys Leu Thr Gly Gly Ser Gly Thr Asn Glu Phe Lys Phe Leu Lys 
        755                 760                 765             


Pro Ile Ile Pro Asn Phe Gln Val His Asp Thr Gly Arg Asn Met Gly 
    770                 775                 780                 


Glu Ile Glu Asn Phe Arg Asn Ser Phe Gly Leu Asn Ile Gln 
785                 790                 795             


<210>  1140
<211>  505
<212>  PRT
<213>  Human

<400>  1140

Met Arg Leu Arg Arg Leu Ala Leu Phe Pro Gly Val Ala Leu Leu Leu 
1               5                   10                  15      


Ala Ala Ala Arg Leu Ala Ala Ala Ser Asp Val Leu Glu Leu Thr Asp 
            20                  25                  30          


Asp Asn Phe Glu Ser Arg Ile Ser Asp Thr Gly Ser Ala Gly Leu Met 
        35                  40                  45              


Leu Val Glu Phe Phe Ala Pro Trp Cys Gly His Cys Lys Arg Leu Ala 
    50                  55                  60                  


Pro Glu Tyr Glu Ala Ala Ala Thr Arg Leu Lys Gly Ile Val Pro Leu 
65                  70                  75                  80  


Ala Lys Val Asp Cys Thr Ala Asn Thr Asn Thr Cys Asn Lys Tyr Gly 
                85                  90                  95      


Val Ser Gly Tyr Pro Thr Leu Lys Ile Phe Arg Asp Gly Glu Glu Ala 
            100                 105                 110         


Gly Ala Tyr Asp Gly Pro Arg Thr Ala Asp Gly Ile Val Ser His Leu 
        115                 120                 125             


Lys Lys Gln Ala Gly Pro Ala Ser Val Pro Leu Arg Thr Glu Glu Glu 
    130                 135                 140                 


Phe Lys Lys Phe Ile Ser Asp Lys Asp Ala Ser Ile Val Gly Phe Phe 
145                 150                 155                 160 


Asp Asp Ser Phe Ser Glu Ala His Ser Glu Phe Leu Lys Ala Ala Ser 
                165                 170                 175     


Asn Leu Arg Asp Asn Tyr Arg Phe Ala His Thr Asn Val Glu Ser Leu 
            180                 185                 190         


Val Asn Glu Tyr Asp Asp Asn Gly Glu Gly Ile Ile Leu Phe Arg Pro 
        195                 200                 205             


Ser His Leu Thr Asn Lys Phe Glu Asp Lys Thr Val Ala Tyr Thr Glu 
    210                 215                 220                 


Gln Lys Met Thr Ser Gly Lys Ile Lys Lys Phe Ile Gln Glu Asn Ile 
225                 230                 235                 240 


Phe Gly Ile Cys Pro His Met Thr Glu Asp Asn Lys Asp Leu Ile Gln 
                245                 250                 255     


Gly Lys Asp Leu Leu Ile Ala Tyr Tyr Asp Val Asp Tyr Glu Lys Asn 
            260                 265                 270         


Ala Lys Gly Ser Asn Tyr Trp Arg Asn Arg Val Met Met Val Ala Lys 
        275                 280                 285             


Lys Phe Leu Asp Ala Gly His Lys Leu Asn Phe Ala Val Ala Ser Arg 
    290                 295                 300                 


Lys Thr Phe Ser His Glu Leu Ser Asp Phe Gly Leu Glu Ser Thr Ala 
305                 310                 315                 320 


Gly Glu Ile Pro Val Val Ala Ile Arg Thr Ala Lys Gly Glu Lys Phe 
                325                 330                 335     


Val Met Gln Glu Glu Phe Ser Arg Asp Gly Lys Ala Leu Glu Arg Phe 
            340                 345                 350         


Leu Gln Asp Tyr Phe Asp Gly Asn Leu Lys Arg Tyr Leu Lys Ser Glu 
        355                 360                 365             


Pro Ile Pro Glu Ser Asn Asp Gly Pro Val Lys Val Val Val Ala Glu 
    370                 375                 380                 


Asn Phe Asp Glu Ile Val Asn Asn Glu Asn Lys Asp Val Leu Ile Glu 
385                 390                 395                 400 


Phe Tyr Ala Pro Trp Cys Gly His Cys Lys Asn Leu Glu Pro Lys Tyr 
                405                 410                 415     


Lys Glu Leu Gly Glu Lys Leu Ser Lys Asp Pro Asn Ile Val Ile Ala 
            420                 425                 430         


Lys Met Asp Ala Thr Ala Asn Asp Val Pro Ser Pro Tyr Glu Val Arg 
        435                 440                 445             


Gly Phe Pro Thr Ile Tyr Phe Ser Pro Ala Asn Lys Lys Leu Asn Pro 
    450                 455                 460                 


Lys Lys Tyr Glu Gly Gly Arg Glu Leu Ser Asp Phe Ile Ser Tyr Leu 
465                 470                 475                 480 


Gln Arg Glu Ala Thr Asn Pro Pro Val Ile Gln Glu Glu Lys Pro Lys 
                485                 490                 495     


Lys Lys Lys Lys Ala Gln Glu Asp Leu 
            500                 505 


<210>  1141
<211>  490
<212>  PRT
<213>  Human

<400>  1141

Met Lys Pro Lys Leu Met Tyr Gln Glu Leu Lys Val Pro Ala Glu Glu 
1               5                   10                  15      


Pro Ala Asn Glu Leu Pro Met Asn Glu Ile Glu Ala Trp Lys Ala Ala 
            20                  25                  30          


Glu Lys Lys Ala Arg Trp Val Leu Leu Val Leu Ile Leu Ala Val Val 
        35                  40                  45              


Gly Phe Gly Ala Leu Met Thr Gln Leu Phe Leu Trp Glu Tyr Gly Asp 
    50                  55                  60                  


Leu His Leu Phe Gly Pro Asn Gln Arg Pro Ala Pro Cys Tyr Asp Pro 
65                  70                  75                  80  


Cys Glu Ala Val Leu Val Glu Ser Ile Pro Glu Gly Leu Asp Phe Pro 
                85                  90                  95      


Asn Ala Ser Thr Gly Asn Pro Ser Thr Ser Gln Ala Trp Leu Gly Leu 
            100                 105                 110         


Leu Ala Gly Ala His Ser Ser Leu Asp Ile Ala Ser Phe Tyr Trp Thr 
        115                 120                 125             


Leu Thr Asn Asn Asp Thr His Thr Gln Glu Pro Ser Ala Gln Gln Gly 
    130                 135                 140                 


Glu Glu Val Leu Arg Gln Leu Gln Thr Leu Ala Pro Lys Gly Val Asn 
145                 150                 155                 160 


Val Arg Ile Ala Val Ser Lys Pro Ser Gly Pro Gln Pro Gln Ala Asp 
                165                 170                 175     


Leu Gln Ala Leu Leu Gln Ser Gly Ala Gln Val Arg Met Val Asp Met 
            180                 185                 190         


Gln Lys Leu Thr His Gly Val Leu His Thr Lys Phe Trp Val Val Asp 
        195                 200                 205             


Gln Thr His Phe Tyr Leu Gly Ser Ala Asn Met Asp Trp Arg Ser Leu 
    210                 215                 220                 


Thr Gln Val Lys Glu Leu Gly Val Val Met Tyr Asn Cys Ser Cys Leu 
225                 230                 235                 240 


Ala Arg Asp Leu Thr Lys Ile Phe Glu Ala Tyr Trp Phe Leu Gly Gln 
                245                 250                 255     


Ala Gly Ser Ser Ile Pro Ser Thr Trp Pro Arg Phe Tyr Asp Thr Arg 
            260                 265                 270         


Tyr Asn Gln Glu Thr Pro Met Glu Ile Cys Leu Asn Gly Thr Pro Ala 
        275                 280                 285             


Leu Ala Tyr Leu Ala Ser Ala Pro Pro Pro Leu Cys Pro Ser Gly Arg 
    290                 295                 300                 


Thr Pro Asp Leu Lys Ala Leu Leu Asn Val Val Asp Asn Ala Arg Ser 
305                 310                 315                 320 


Phe Ile Tyr Val Ala Val Met Asn Tyr Leu Pro Thr Leu Glu Phe Ser 
                325                 330                 335     


His Pro His Arg Phe Trp Pro Ala Ile Asp Asp Gly Leu Arg Arg Ala 
            340                 345                 350         


Thr Tyr Glu Arg Gly Val Lys Val Arg Leu Leu Ile Ser Cys Trp Gly 
        355                 360                 365             


His Ser Glu Pro Ser Met Arg Ala Phe Leu Leu Ser Leu Ala Ala Leu 
    370                 375                 380                 


Arg Asp Asn His Thr His Ser Asp Ile Gln Val Lys Leu Phe Val Val 
385                 390                 395                 400 


Pro Ala Asp Glu Ala Gln Ala Arg Ile Pro Tyr Ala Arg Val Asn His 
                405                 410                 415     


Asn Lys Tyr Met Val Thr Glu Arg Ala Thr Tyr Ile Gly Thr Ser Asn 
            420                 425                 430         


Trp Ser Gly Asn Tyr Phe Thr Glu Thr Ala Gly Thr Ser Leu Leu Val 
        435                 440                 445             


Thr Gln Asn Gly Arg Gly Gly Leu Arg Ser Gln Leu Glu Ala Ile Phe 
    450                 455                 460                 


Leu Arg Asp Trp Asp Ser Pro Tyr Ser His Asp Leu Asp Thr Ser Ala 
465                 470                 475                 480 


Asp Ser Val Gly Asn Ala Cys Arg Leu Leu 
                485                 490 


<210>  1142
<211>  520
<212>  PRT
<213>  Human

<400>  1142

Met Gly Lys Arg Gln His Gln Lys Asp Lys Met Tyr Ile Thr Cys Ala 
1               5                   10                  15      


Glu Tyr Thr His Phe Tyr Gly Gly Lys Lys Pro Asp Leu Pro Gln Thr 
            20                  25                  30          


Asn Phe Arg Arg Leu Pro Phe Asp His Cys Ser Leu Ser Leu Gln Pro 
        35                  40                  45              


Phe Val Tyr Pro Val Cys Thr Pro Asp Gly Ile Val Phe Asp Leu Leu 
    50                  55                  60                  


Asn Ile Val Pro Trp Leu Lys Lys Tyr Gly Thr Asn Pro Ser Asn Gly 
65                  70                  75                  80  


Glu Lys Leu Asp Gly Arg Ser Leu Ile Lys Leu Asn Phe Ser Lys Asn 
                85                  90                  95      


Ser Glu Gly Lys Tyr His Cys Pro Val Leu Phe Thr Val Phe Thr Asn 
            100                 105                 110         


Asn Thr His Ile Val Ala Val Arg Thr Thr Gly Asn Val Tyr Ala Tyr 
        115                 120                 125             


Glu Ala Val Glu Gln Leu Asn Ile Lys Ala Lys Asn Phe Arg Asp Leu 
    130                 135                 140                 


Leu Thr Asp Glu Pro Phe Ser Arg Gln Asp Ile Ile Thr Leu Gln Asp 
145                 150                 155                 160 


Pro Thr Asn Leu Asp Lys Phe Asn Val Ser Asn Phe Tyr His Val Lys 
                165                 170                 175     


Asn Asn Met Lys Ile Ile Asp Pro Asp Glu Glu Lys Ala Lys Gln Asp 
            180                 185                 190         


Pro Ser Tyr Tyr Leu Lys Asn Thr Asn Ala Glu Thr Arg Glu Thr Leu 
        195                 200                 205             


Gln Glu Leu Tyr Lys Glu Phe Lys Gly Asp Glu Ile Leu Ala Ala Thr 
    210                 215                 220                 


Met Lys Ala Pro Glu Lys Lys Lys Val Asp Lys Leu Asn Ala Ala His 
225                 230                 235                 240 


Tyr Ser Thr Gly Lys Val Ser Ala Ser Phe Thr Ser Thr Ala Met Val 
                245                 250                 255     


Pro Glu Thr Thr His Glu Ala Ala Ala Ile Asp Glu Asp Val Leu Arg 
            260                 265                 270         


Tyr Gln Phe Val Lys Lys Lys Gly Tyr Val Arg Leu His Thr Asn Lys 
        275                 280                 285             


Gly Asp Leu Asn Leu Glu Leu His Cys Asp Leu Thr Pro Lys Thr Cys 
    290                 295                 300                 


Glu Asn Phe Ile Arg Leu Cys Lys Lys His Tyr Tyr Asp Gly Thr Ile 
305                 310                 315                 320 


Phe His Arg Ser Ile Arg Asn Phe Val Ile Gln Gly Gly Asp Pro Thr 
                325                 330                 335     


Gly Thr Gly Thr Gly Gly Glu Ser Tyr Trp Gly Lys Pro Phe Lys Asp 
            340                 345                 350         


Glu Phe Arg Pro Asn Leu Ser His Thr Gly Arg Gly Ile Leu Ser Met 
        355                 360                 365             


Ala Asn Ser Gly Pro Asn Ser Asn Arg Ser Gln Phe Phe Ile Thr Phe 
    370                 375                 380                 


Arg Ser Cys Ala Tyr Leu Asp Lys Lys His Thr Ile Phe Gly Arg Val 
385                 390                 395                 400 


Val Gly Gly Phe Asp Val Leu Thr Ala Met Glu Asn Val Glu Ser Asp 
                405                 410                 415     


Pro Lys Thr Asp Arg Pro Lys Glu Glu Ile Arg Ile Asp Ala Thr Thr 
            420                 425                 430         


Val Phe Val Asp Pro Tyr Glu Glu Ala Asp Ala Gln Ile Ala Gln Glu 
        435                 440                 445             


Arg Lys Thr Gln Leu Lys Val Ala Pro Glu Thr Lys Val Lys Ser Ser 
    450                 455                 460                 


Gln Pro Gln Ala Gly Ser Gln Gly Pro Gln Thr Phe Arg Gln Gly Val 
465                 470                 475                 480 


Gly Lys Tyr Ile Asn Pro Ala Ala Thr Lys Arg Ala Ala Glu Glu Glu 
                485                 490                 495     


Pro Ser Thr Ser Ala Thr Val Pro Met Ser Lys Lys Lys Pro Ser Arg 
            500                 505                 510         


Gly Phe Gly Asp Phe Ser Ser Trp 
        515                 520 


<210>  1143
<211>  420
<212>  PRT
<213>  Human

<400>  1143

Met Glu Thr Phe Asp Pro Thr Glu Leu Pro Glu Leu Leu Lys Leu Tyr 
1               5                   10                  15      


Tyr Arg Arg Leu Phe Pro Tyr Ser Gln Tyr Tyr Arg Trp Leu Asn Tyr 
            20                  25                  30          


Gly Gly Val Ile Lys Asn Tyr Phe Gln His Arg Glu Phe Ser Phe Thr 
        35                  40                  45              


Leu Lys Asp Asp Ile Tyr Ile Arg Tyr Gln Ser Phe Asn Asn Gln Ser 
    50                  55                  60                  


Asp Leu Glu Lys Glu Met Gln Lys Met Asn Pro Tyr Lys Ile Asp Ile 
65                  70                  75                  80  


Gly Ala Val Tyr Ser His Arg Pro Asn Gln His Asn Thr Val Lys Leu 
                85                  90                  95      


Gly Ala Phe Gln Ala Gln Glu Lys Glu Leu Val Phe Asp Ile Asp Met 
            100                 105                 110         


Thr Asp Tyr Asp Asp Val Arg Arg Cys Cys Ser Ser Ala Asp Ile Cys 
        115                 120                 125             


Pro Lys Cys Trp Thr Leu Met Thr Met Ala Ile Arg Ile Ile Asp Arg 
    130                 135                 140                 


Ala Leu Lys Glu Asp Phe Gly Phe Lys His Arg Leu Trp Val Tyr Ser 
145                 150                 155                 160 


Gly Arg Arg Gly Val His Cys Trp Val Cys Asp Glu Ser Val Arg Lys 
                165                 170                 175     


Leu Ser Ser Ala Val Arg Ser Gly Ile Val Glu Tyr Leu Ser Leu Val 
            180                 185                 190         


Lys Gly Gly Gln Asp Val Lys Lys Lys Val His Leu Ser Glu Lys Ile 
        195                 200                 205             


His Pro Phe Ile Arg Lys Ser Ile Asn Ile Ile Lys Lys Tyr Phe Glu 
    210                 215                 220                 


Glu Tyr Ala Leu Val Asn Gln Asp Ile Leu Glu Asn Lys Glu Ser Trp 
225                 230                 235                 240 


Asp Lys Ile Leu Ala Leu Val Pro Glu Thr Ile His Asp Glu Leu Gln 
                245                 250                 255     


Gln Ser Phe Gln Lys Ser His Asn Ser Leu Gln Arg Trp Glu His Leu 
            260                 265                 270         


Lys Lys Val Ala Ser Arg Tyr Gln Asn Asn Ile Lys Asn Asp Lys Tyr 
        275                 280                 285             


Gly Pro Trp Leu Glu Trp Glu Ile Met Leu Gln Tyr Cys Phe Pro Arg 
    290                 295                 300                 


Leu Asp Ile Asn Val Ser Lys Gly Ile Asn His Leu Leu Lys Ser Pro 
305                 310                 315                 320 


Phe Ser Val His Pro Lys Thr Gly Arg Ile Ser Val Pro Ile Asp Leu 
                325                 330                 335     


Gln Lys Val Asp Gln Phe Asp Pro Phe Thr Val Pro Thr Ile Ser Phe 
            340                 345                 350         


Ile Cys Arg Glu Leu Asp Ala Ile Ser Thr Asn Glu Glu Glu Lys Glu 
        355                 360                 365             


Glu Asn Glu Ala Glu Ser Asp Val Lys His Arg Thr Arg Asp Tyr Lys 
    370                 375                 380                 


Lys Thr Ser Leu Ala Pro Tyr Val Lys Val Phe Glu His Phe Leu Glu 
385                 390                 395                 400 


Asn Leu Asp Lys Ser Arg Lys Gly Glu Leu Leu Lys Lys Ser Asp Leu 
                405                 410                 415     


Gln Lys Asp Phe 
            420 


<210>  1144
<211>  263
<212>  PRT
<213>  Human

<400>  1144

Met Phe Arg Asn Gln Tyr Asp Asn Asp Val Thr Val Trp Ser Pro Gln 
1               5                   10                  15      


Gly Arg Ile His Gln Ile Glu Tyr Ala Met Glu Ala Val Lys Gln Gly 
            20                  25                  30          


Ser Ala Thr Val Gly Leu Lys Ser Lys Thr His Ala Val Leu Val Ala 
        35                  40                  45              


Leu Lys Arg Ala Gln Ser Glu Leu Ala Ala His Gln Lys Lys Ile Leu 
    50                  55                  60                  


His Val Asp Asn His Ile Gly Ile Ser Ile Ala Gly Leu Thr Ala Asp 
65                  70                  75                  80  


Ala Arg Leu Leu Cys Asn Phe Met Arg Gln Glu Cys Leu Asp Ser Arg 
                85                  90                  95      


Phe Val Phe Asp Arg Pro Leu Pro Val Ser Arg Leu Val Ser Leu Ile 
            100                 105                 110         


Gly Ser Lys Thr Gln Ile Pro Thr Gln Arg Tyr Gly Arg Arg Pro Tyr 
        115                 120                 125             


Gly Val Gly Leu Leu Ile Ala Gly Tyr Asp Asp Met Gly Pro His Ile 
    130                 135                 140                 


Phe Gln Thr Cys Pro Ser Ala Asn Tyr Phe Asp Cys Arg Ala Met Ser 
145                 150                 155                 160 


Ile Gly Ala Arg Ser Gln Ser Ala Arg Thr Tyr Leu Glu Arg His Met 
                165                 170                 175     


Ser Glu Phe Met Glu Cys Asn Leu Asn Glu Leu Val Lys His Gly Leu 
            180                 185                 190         


Arg Ala Leu Arg Glu Thr Leu Pro Ala Glu Gln Asp Leu Thr Thr Lys 
        195                 200                 205             


Asn Val Ser Ile Gly Ile Val Gly Lys Asp Leu Glu Phe Thr Ile Tyr 
    210                 215                 220                 


Asp Asp Asp Asp Val Ser Pro Phe Leu Glu Gly Leu Glu Glu Arg Pro 
225                 230                 235                 240 


Gln Arg Lys Ala Gln Pro Ala Gln Pro Ala Asp Glu Pro Ala Glu Lys 
                245                 250                 255     


Ala Asp Glu Pro Met Glu His 
            260             


<210>  1145
<211>  1505
<212>  PRT
<213>  Human

<400>  1145

Met Ala Pro Thr Trp Gly Pro Gly Met Val Ser Val Val Gly Pro Met 
1               5                   10                  15      


Gly Leu Leu Val Val Leu Leu Val Gly Gly Cys Ala Ala Glu Glu Pro 
            20                  25                  30          


Pro Arg Phe Ile Lys Glu Pro Lys Asp Gln Ile Gly Val Ser Gly Gly 
        35                  40                  45              


Val Ala Ser Phe Val Cys Gln Ala Thr Gly Asp Pro Lys Pro Arg Val 
    50                  55                  60                  


Thr Trp Asn Lys Lys Gly Lys Lys Val Asn Ser Gln Arg Phe Glu Thr 
65                  70                  75                  80  


Ile Glu Phe Asp Glu Ser Ala Gly Ala Val Leu Arg Ile Gln Pro Leu 
                85                  90                  95      


Arg Thr Pro Arg Asp Glu Asn Val Tyr Glu Cys Val Ala Gln Asn Ser 
            100                 105                 110         


Val Gly Glu Ile Thr Val His Ala Lys Leu Thr Val Leu Arg Glu Asp 
        115                 120                 125             


Gln Leu Pro Ser Gly Phe Pro Asn Ile Asp Met Gly Pro Gln Leu Lys 
    130                 135                 140                 


Val Val Glu Arg Thr Arg Thr Ala Thr Met Leu Cys Ala Ala Ser Gly 
145                 150                 155                 160 


Asn Pro Asp Pro Glu Ile Thr Trp Phe Lys Asp Phe Leu Pro Val Asp 
                165                 170                 175     


Pro Ser Ala Ser Asn Gly Arg Ile Lys Gln Leu Arg Ser Gly Ala Leu 
            180                 185                 190         


Gln Ile Glu Ser Ser Glu Glu Thr Asp Gln Gly Lys Tyr Glu Cys Val 
        195                 200                 205             


Ala Thr Asn Ser Ala Gly Val Arg Tyr Ser Ser Pro Ala Asn Leu Tyr 
    210                 215                 220                 


Val Arg Glu Leu Arg Glu Val Arg Arg Val Ala Pro Arg Phe Ser Ile 
225                 230                 235                 240 


Leu Pro Met Ser His Glu Ile Met Pro Gly Gly Asn Val Asn Ile Thr 
                245                 250                 255     


Cys Val Ala Val Gly Ser Pro Met Pro Tyr Val Lys Trp Met Gln Gly 
            260                 265                 270         


Ala Glu Asp Leu Thr Pro Glu Asp Asp Met Pro Val Gly Arg Asn Val 
        275                 280                 285             


Leu Glu Leu Thr Asp Val Lys Asp Ser Ala Asn Tyr Thr Cys Val Ala 
    290                 295                 300                 


Met Ser Ser Leu Gly Val Ile Glu Ala Val Ala Gln Ile Thr Val Lys 
305                 310                 315                 320 


Ser Leu Pro Lys Ala Pro Gly Thr Pro Met Val Thr Glu Asn Thr Ala 
                325                 330                 335     


Thr Ser Ile Thr Ile Thr Trp Asp Ser Gly Asn Pro Asp Pro Val Ser 
            340                 345                 350         


Tyr Tyr Val Ile Glu Tyr Lys Ser Lys Ser Gln Asp Gly Pro Tyr Gln 
        355                 360                 365             


Ile Lys Glu Asp Ile Thr Thr Thr Arg Tyr Ser Ile Gly Gly Leu Ser 
    370                 375                 380                 


Pro Asn Ser Glu Tyr Glu Ile Trp Val Ser Ala Val Asn Ser Ile Gly 
385                 390                 395                 400 


Gln Gly Pro Pro Ser Glu Ser Val Val Thr Arg Thr Gly Glu Gln Ala 
                405                 410                 415     


Pro Ala Ser Ala Pro Arg Asn Val Gln Ala Arg Met Leu Ser Ala Thr 
            420                 425                 430         


Thr Met Ile Val Gln Trp Glu Glu Pro Val Glu Pro Asn Gly Leu Ile 
        435                 440                 445             


Arg Gly Tyr Arg Val Tyr Tyr Thr Met Glu Pro Glu His Pro Val Gly 
    450                 455                 460                 


Asn Trp Gln Lys His Asn Val Asp Asp Ser Leu Leu Thr Thr Val Gly 
465                 470                 475                 480 


Ser Leu Leu Glu Asp Glu Thr Tyr Thr Val Arg Val Leu Ala Phe Thr 
                485                 490                 495     


Ser Val Gly Asp Gly Pro Leu Ser Asp Pro Ile Gln Val Lys Thr Gln 
            500                 505                 510         


Gln Gly Val Pro Gly Gln Pro Met Asn Leu Arg Ala Glu Ala Arg Ser 
        515                 520                 525             


Glu Thr Ser Ile Thr Leu Ser Trp Ser Pro Pro Arg Gln Glu Ser Ile 
    530                 535                 540                 


Ile Lys Tyr Glu Leu Leu Phe Arg Glu Gly Asp His Gly Arg Glu Val 
545                 550                 555                 560 


Gly Arg Thr Phe Asp Pro Thr Thr Ser Tyr Val Val Glu Asp Leu Lys 
                565                 570                 575     


Pro Asn Thr Glu Tyr Ala Phe Arg Leu Ala Ala Arg Ser Pro Gln Gly 
            580                 585                 590         


Leu Gly Ala Phe Thr Pro Val Val Arg Gln Arg Thr Leu Gln Ser Ile 
        595                 600                 605             


Ser Pro Lys Asn Phe Lys Val Lys Met Ile Met Lys Thr Ser Val Leu 
    610                 615                 620                 


Leu Ser Trp Glu Phe Pro Asp Asn Tyr Asn Ser Pro Thr Pro Tyr Lys 
625                 630                 635                 640 


Ile Gln Tyr Asn Gly Leu Thr Leu Asp Val Asp Gly Arg Thr Thr Lys 
                645                 650                 655     


Lys Leu Ile Thr His Leu Lys Pro His Thr Phe Tyr Asn Phe Val Leu 
            660                 665                 670         


Thr Asn Arg Gly Ser Ser Leu Gly Gly Leu Gln Gln Thr Val Thr Ala 
        675                 680                 685             


Trp Thr Ala Phe Asn Leu Leu Asn Gly Lys Pro Ser Val Ala Pro Lys 
    690                 695                 700                 


Pro Asp Ala Asp Gly Phe Ile Met Val Tyr Leu Pro Asp Gly Gln Ser 
705                 710                 715                 720 


Pro Val Pro Val Gln Ser Tyr Phe Ile Val Met Val Pro Leu Arg Lys 
                725                 730                 735     


Ser Arg Gly Gly Gln Phe Leu Thr Pro Leu Gly Ser Pro Glu Asp Met 
            740                 745                 750         


Asp Leu Glu Glu Leu Ile Gln Asp Ile Ser Arg Leu Gln Arg Arg Ser 
        755                 760                 765             


Leu Arg His Ser Arg Gln Leu Glu Val Pro Arg Pro Tyr Ile Ala Ala 
    770                 775                 780                 


Arg Phe Ser Val Leu Pro Pro Thr Phe His Pro Gly Asp Gln Lys Gln 
785                 790                 795                 800 


Tyr Gly Gly Phe Asp Asn Arg Gly Leu Glu Pro Gly His Arg Tyr Val 
                805                 810                 815     


Leu Phe Val Leu Ala Val Leu Gln Lys Ser Glu Pro Thr Phe Ala Ala 
            820                 825                 830         


Ser Pro Phe Ser Asp Pro Phe Gln Leu Asp Asn Pro Asp Pro Gln Pro 
        835                 840                 845             


Ile Val Asp Gly Glu Glu Gly Leu Ile Trp Val Ile Gly Pro Val Leu 
    850                 855                 860                 


Ala Val Val Phe Ile Ile Cys Ile Val Ile Ala Ile Leu Leu Tyr Lys 
865                 870                 875                 880 


Asn Lys Pro Asp Ser Lys Arg Lys Asp Ser Glu Pro Arg Thr Lys Cys 
                885                 890                 895     


Leu Leu Asn Asn Ala Asp Leu Ala Pro His His Pro Lys Asp Pro Val 
            900                 905                 910         


Glu Met Arg Arg Ile Asn Phe Gln Thr Pro Gly Met Leu Ser His Pro 
        915                 920                 925             


Pro Ile Pro Ile Ala Asp Met Ala Glu His Thr Glu Arg Leu Lys Ala 
    930                 935                 940                 


Asn Asp Ser Leu Lys Leu Ser Gln Glu Tyr Glu Ser Ile Asp Pro Gly 
945                 950                 955                 960 


Gln Gln Phe Thr Trp Glu His Ser Asn Leu Glu Val Asn Lys Pro Lys 
                965                 970                 975     


Asn Arg Tyr Ala Asn Val Ile Ala Tyr Asp His Ser Arg Val Ile Leu 
            980                 985                 990         


Gln Pro Ile Glu Gly Ile Met Gly  Ser Asp Tyr Ile Asn  Ala Asn Tyr 
        995                 1000                 1005             


Val Asp  Gly Tyr Arg Cys Gln  Asn Ala Tyr Ile Ala  Thr Gln Gly 
    1010                 1015                 1020             


Pro Leu  Pro Glu Thr Phe Gly  Asp Phe Trp Arg Met  Val Trp Glu 
    1025                 1030                 1035             


Gln Arg  Ser Ala Thr Ile Val  Met Met Thr Arg Leu  Glu Glu Lys 
    1040                 1045                 1050             


Ser Arg  Ile Lys Cys Asp Gln  Tyr Trp Pro Asn Arg  Gly Thr Glu 
    1055                 1060                 1065             


Thr Tyr  Gly Phe Ile Gln Val  Thr Leu Leu Asp Thr  Ile Glu Leu 
    1070                 1075                 1080             


Ala Thr  Phe Cys Val Arg Thr  Phe Ser Leu His Lys  Asn Gly Ser 
    1085                 1090                 1095             


Ser Glu  Lys Arg Glu Val Arg  Gln Phe Gln Phe Thr  Ala Trp Pro 
    1100                 1105                 1110             


Asp His  Gly Val Pro Glu Tyr  Pro Thr Pro Phe Leu  Ala Phe Leu 
    1115                 1120                 1125             


Arg Arg  Val Lys Thr Cys Asn  Pro Pro Asp Ala Gly  Pro Ile Val 
    1130                 1135                 1140             


Val His  Cys Ser Ala Gly Val  Gly Arg Thr Gly Cys  Phe Ile Val 
    1145                 1150                 1155             


Ile Asp  Ala Met Leu Glu Arg  Ile Lys Pro Glu Lys  Thr Val Asp 
    1160                 1165                 1170             


Val Tyr  Gly His Val Thr Leu  Met Arg Ser Gln Arg  Asn Tyr Met 
    1175                 1180                 1185             


Val Gln  Thr Glu Asp Gln Tyr  Ser Phe Ile His Glu  Ala Leu Leu 
    1190                 1195                 1200             


Glu Ala  Val Gly Cys Gly Asn  Thr Glu Val Pro Ala  Arg Ser Leu 
    1205                 1210                 1215             


Tyr Ala  Tyr Ile Gln Lys Leu  Ala Gln Val Glu Pro  Gly Glu His 
    1220                 1225                 1230             


Val Thr  Gly Met Glu Leu Glu  Phe Lys Arg Leu Ala  Asn Ser Lys 
    1235                 1240                 1245             


Ala His  Thr Ser Arg Phe Ile  Ser Ala Asn Leu Pro  Cys Asn Lys 
    1250                 1255                 1260             


Phe Lys  Asn Arg Leu Val Asn  Ile Met Pro Tyr Glu  Ser Thr Arg 
    1265                 1270                 1275             


Val Cys  Leu Gln Pro Ile Arg  Gly Val Glu Gly Ser  Asp Tyr Ile 
    1280                 1285                 1290             


Asn Ala  Ser Phe Ile Asp Gly  Tyr Arg Gln Gln Lys  Ala Tyr Ile 
    1295                 1300                 1305             


Ala Thr  Gln Gly Pro Leu Ala  Glu Thr Thr Glu Asp  Phe Trp Arg 
    1310                 1315                 1320             


Met Leu  Trp Glu Asn Asn Ser  Thr Ile Val Val Met  Leu Thr Lys 
    1325                 1330                 1335             


Leu Arg  Glu Met Gly Arg Glu  Lys Cys His Gln Tyr  Trp Pro Ala 
    1340                 1345                 1350             


Glu Arg  Ser Ala Arg Tyr Gln  Tyr Phe Val Val Asp  Pro Met Ala 
    1355                 1360                 1365             


Glu Tyr  Asn Met Pro Gln Tyr  Ile Leu Arg Glu Phe  Lys Val Thr 
    1370                 1375                 1380             


Asp Ala  Arg Asp Gly Gln Ser  Arg Thr Val Arg Gln  Phe Gln Phe 
    1385                 1390                 1395             


Thr Asp  Trp Pro Glu Gln Gly  Val Pro Lys Ser Gly  Glu Gly Phe 
    1400                 1405                 1410             


Ile Asp  Phe Ile Gly Gln Val  His Lys Thr Lys Glu  Gln Phe Gly 
    1415                 1420                 1425             


Gln Asp  Gly Pro Ile Ser Val  His Cys Ser Ala Gly  Val Gly Arg 
    1430                 1435                 1440             


Thr Gly  Val Phe Ile Thr Leu  Ser Ile Val Leu Glu  Arg Met Arg 
    1445                 1450                 1455             


Tyr Glu  Gly Val Val Asp Ile  Phe Gln Thr Val Lys  Met Leu Arg 
    1460                 1465                 1470             


Thr Gln  Arg Pro Ala Met Val  Gln Thr Glu Asp Glu  Tyr Gln Phe 
    1475                 1480                 1485             


Cys Tyr  Gln Ala Ala Leu Glu  Tyr Leu Gly Ser Phe  Asp His Tyr 
    1490                 1495                 1500             


Ala Thr  
    1505 


<210>  1146
<211>  403
<212>  PRT
<213>  Human

<400>  1146

Met Ala Gly Ala Ala Thr Gln Ala Ser Leu Glu Ser Ala Pro Arg Ile 
1               5                   10                  15      


Met Arg Leu Val Ala Glu Cys Ser Arg Ser Arg Ala Arg Ala Gly Glu 
            20                  25                  30          


Leu Trp Leu Pro His Gly Thr Val Ala Thr Pro Val Phe Met Pro Val 
        35                  40                  45              


Gly Thr Gln Ala Thr Met Lys Gly Ile Thr Thr Glu Gln Leu Asp Ala 
    50                  55                  60                  


Leu Gly Cys Arg Ile Cys Leu Gly Asn Thr Tyr His Leu Gly Leu Arg 
65                  70                  75                  80  


Pro Gly Pro Glu Leu Ile Gln Lys Ala Asn Gly Leu His Gly Phe Met 
                85                  90                  95      


Asn Trp Pro His Asn Leu Leu Thr Asp Ser Gly Gly Phe Gln Met Val 
            100                 105                 110         


Ser Leu Val Ser Leu Ser Glu Val Thr Glu Glu Gly Val Arg Phe Arg 
        115                 120                 125             


Ser Pro Tyr Asp Gly Asn Glu Thr Leu Leu Ser Pro Glu Lys Ser Val 
    130                 135                 140                 


Gln Ile Gln Asn Ala Leu Gly Ser Asp Ile Ile Met Gln Leu Asp Asp 
145                 150                 155                 160 


Val Val Ser Ser Thr Val Thr Gly Pro Arg Val Glu Glu Ala Met Tyr 
                165                 170                 175     


Arg Ser Ile Arg Trp Leu Asp Arg Cys Ile Ala Ala His Gln Arg Pro 
            180                 185                 190         


Asp Lys Gln Asn Leu Phe Ala Ile Ile Gln Gly Gly Leu Asp Ala Asp 
        195                 200                 205             


Leu Arg Ala Thr Cys Leu Glu Glu Met Thr Lys Arg Asp Val Pro Gly 
    210                 215                 220                 


Phe Ala Ile Gly Gly Leu Ser Gly Gly Glu Ser Lys Ser Gln Phe Trp 
225                 230                 235                 240 


Arg Met Val Ala Leu Ser Thr Ser Arg Leu Pro Lys Asp Lys Pro Arg 
                245                 250                 255     


Tyr Leu Met Gly Val Gly Tyr Ala Thr Asp Leu Val Val Cys Val Ala 
            260                 265                 270         


Leu Gly Cys Asp Met Phe Asp Cys Val Phe Pro Thr Arg Thr Ala Arg 
        275                 280                 285             


Phe Gly Ser Ala Leu Val Pro Thr Gly Asn Leu Gln Leu Arg Lys Lys 
    290                 295                 300                 


Val Phe Glu Lys Asp Phe Gly Pro Ile Asp Pro Glu Cys Thr Cys Pro 
305                 310                 315                 320 


Thr Cys Gln Lys His Ser Arg Ala Phe Leu His Ala Leu Leu His Ser 
                325                 330                 335     


Asp Asn Thr Ala Ala Leu His His Leu Thr Val His Asn Ile Ala Tyr 
            340                 345                 350         


Gln Leu Gln Leu Met Ser Ala Val Arg Thr Ser Ile Val Glu Lys Arg 
        355                 360                 365             


Phe Pro Asp Phe Val Arg Asp Phe Met Gly Ala Met Tyr Gly Asp Pro 
    370                 375                 380                 


Thr Leu Cys Pro Thr Trp Ala Thr Asp Ala Leu Ala Ser Val Gly Ile 
385                 390                 395                 400 


Thr Leu Gly 
            


<210>  1147
<211>  134
<212>  PRT
<213>  Human

<400>  1147

Met Pro Ala Asp Leu Ser Gly Thr Trp Thr Leu Leu Ser Ser Asp Asn 
1               5                   10                  15      


Phe Glu Gly Tyr Met Leu Ala Leu Gly Ile Asp Phe Ala Thr Arg Lys 
            20                  25                  30          


Ile Ala Lys Leu Leu Lys Pro Gln Lys Val Ile Glu Gln Asn Gly Asp 
        35                  40                  45              


Ser Phe Thr Ile His Thr Asn Ser Ser Leu Arg Asn Tyr Phe Val Lys 
    50                  55                  60                  


Phe Lys Val Gly Glu Glu Phe Asp Glu Asp Asn Arg Gly Leu Asp Asn 
65                  70                  75                  80  


Arg Lys Cys Lys Ser Leu Val Ile Trp Asp Asn Asp Arg Leu Thr Cys 
                85                  90                  95      


Ile Gln Lys Gly Glu Lys Lys Asn Arg Gly Trp Thr His Trp Ile Glu 
            100                 105                 110         


Gly Asp Lys Leu His Leu Glu Met Phe Cys Glu Gly Gln Val Cys Lys 
        115                 120                 125             


Gln Thr Phe Gln Arg Ala 
    130                 


<210>  1148
<211>  217
<212>  PRT
<213>  Human

<400>  1148

Met Pro Thr Pro His Glu Ala Glu Lys Gln Ile Thr Gly Pro Glu Glu 
1               5                   10                  15      


Ala Asp Arg Pro Pro Ser Met Ser Ser His Asp Thr Ala Ser Pro Ala 
            20                  25                  30          


Ala Pro Ser Arg Asn Pro Cys Cys Leu Cys Trp Cys Cys Cys Cys Ser 
        35                  40                  45              


Cys Ser Trp Asn Gln Glu Arg Arg Arg Ala Trp Gln Ala Ser Arg Glu 
    50                  55                  60                  


Ser Lys Leu Gln Pro Leu Pro Ser Cys Glu Val Cys Ala Thr Pro Ser 
65                  70                  75                  80  


Pro Glu Glu Val Gln Ser Trp Ala Gln Ser Phe Asp Lys Leu Met His 
                85                  90                  95      


Ser Pro Ala Gly Arg Ser Val Phe Arg Ala Phe Leu Arg Thr Glu Tyr 
            100                 105                 110         


Ser Glu Glu Asn Met Leu Phe Trp Leu Ala Cys Glu Glu Leu Lys Ala 
        115                 120                 125             


Glu Ala Asn Gln His Val Val Asp Glu Lys Ala Arg Leu Ile Tyr Glu 
    130                 135                 140                 


Asp Tyr Val Ser Ile Leu Ser Pro Lys Glu Val Ser Leu Asp Ser Arg 
145                 150                 155                 160 


Val Arg Glu Gly Ile Asn Lys Lys Met Gln Glu Pro Ser Ala His Thr 
                165                 170                 175     


Phe Asp Asp Ala Gln Leu Gln Ile Tyr Thr Leu Met His Arg Asp Ser 
            180                 185                 190         


Tyr Pro Arg Phe Leu Ser Ser Pro Thr Tyr Arg Ala Leu Leu Leu Gln 
        195                 200                 205             


Gly Pro Ser Gln Ser Ser Ser Glu Ala 
    210                 215         


<210>  1149
<211>  668
<212>  PRT
<213>  Human

<400>  1149

Met Ala Val Tyr Arg Ala Ala Leu Gly Ala Ser Leu Ala Ala Ala Arg 
1               5                   10                  15      


Leu Leu Pro Leu Gly Arg Cys Ser Pro Ser Pro Ala Pro Arg Ser Thr 
            20                  25                  30          


Leu Ser Gly Ala Ala Met Glu Pro Ala Pro Arg Trp Leu Ala Gly Leu 
        35                  40                  45              


Arg Phe Asp Asn Arg Ala Leu Arg Ala Leu Pro Val Glu Ala Pro Pro 
    50                  55                  60                  


Pro Gly Pro Glu Gly Ala Pro Ser Ala Pro Arg Pro Val Pro Gly Ala 
65                  70                  75                  80  


Cys Phe Thr Arg Val Gln Pro Thr Pro Leu Arg Gln Pro Arg Leu Val 
                85                  90                  95      


Ala Leu Ser Glu Pro Ala Leu Ala Leu Leu Gly Leu Gly Ala Pro Pro 
            100                 105                 110         


Ala Arg Glu Ala Glu Ala Glu Ala Ala Leu Phe Phe Ser Gly Asn Ala 
        115                 120                 125             


Leu Leu Pro Gly Ala Glu Pro Ala Ala His Cys Tyr Cys Gly His Gln 
    130                 135                 140                 


Phe Gly Gln Phe Ala Gly Gln Leu Gly Asp Gly Ala Ala Met Tyr Leu 
145                 150                 155                 160 


Gly Glu Val Cys Thr Ala Thr Gly Glu Arg Trp Glu Leu Gln Leu Lys 
                165                 170                 175     


Gly Ala Gly Pro Thr Pro Phe Ser Arg Gln Ala Asp Gly Arg Lys Val 
            180                 185                 190         


Leu Arg Ser Ser Ile Arg Glu Phe Leu Cys Ser Glu Ala Met Phe His 
        195                 200                 205             


Leu Gly Val Pro Thr Thr Arg Ala Gly Ala Cys Val Thr Ser Glu Ser 
    210                 215                 220                 


Thr Val Val Arg Asp Val Phe Tyr Asp Gly Asn Pro Lys Tyr Glu Gln 
225                 230                 235                 240 


Cys Thr Val Val Leu Arg Val Ala Ser Thr Phe Ile Arg Phe Gly Ser 
                245                 250                 255     


Phe Glu Ile Phe Lys Ser Ala Asp Glu His Thr Gly Arg Ala Gly Pro 
            260                 265                 270         


Ser Val Gly Arg Asn Asp Ile Arg Val Gln Leu Leu Asp Tyr Val Ile 
        275                 280                 285             


Ser Ser Phe Tyr Pro Glu Ile Gln Ala Ala His Ala Ser Asp Ser Val 
    290                 295                 300                 


Gln Arg Asn Ala Ala Phe Phe Arg Glu Val Thr Arg Arg Thr Ala Arg 
305                 310                 315                 320 


Met Val Ala Glu Trp Gln Cys Val Gly Phe Cys His Gly Val Leu Asn 
                325                 330                 335     


Thr Asp Asn Met Ser Ile Leu Gly Leu Thr Ile Asp Tyr Gly Pro Phe 
            340                 345                 350         


Gly Phe Leu Asp Arg Tyr Asp Pro Asp His Val Cys Asn Ala Ser Asp 
        355                 360                 365             


Asn Thr Gly Arg Tyr Ala Tyr Ser Lys Gln Pro Glu Val Cys Arg Trp 
    370                 375                 380                 


Asn Leu Arg Lys Leu Ala Glu Ala Leu Gln Pro Glu Leu Pro Leu Glu 
385                 390                 395                 400 


Leu Gly Glu Ala Ile Leu Ala Glu Glu Phe Asp Ala Glu Phe Gln Arg 
                405                 410                 415     


His Tyr Leu Gln Lys Met Arg Arg Lys Leu Gly Leu Val Gln Val Glu 
            420                 425                 430         


Leu Glu Glu Asp Gly Ala Leu Val Ser Lys Leu Leu Glu Thr Met His 
        435                 440                 445             


Leu Thr Gly Ala Asp Phe Thr Asn Thr Phe Tyr Leu Leu Ser Ser Phe 
    450                 455                 460                 


Pro Val Glu Leu Glu Ser Pro Gly Leu Ala Glu Phe Leu Ala Arg Leu 
465                 470                 475                 480 


Met Glu Gln Cys Ala Ser Leu Glu Glu Leu Arg Leu Ala Phe Arg Pro 
                485                 490                 495     


Gln Met Asp Pro Arg Gln Leu Ser Met Met Leu Met Leu Ala Gln Ser 
            500                 505                 510         


Asn Pro Gln Leu Phe Ala Leu Met Gly Thr Arg Ala Gly Ile Ala Arg 
        515                 520                 525             


Glu Leu Glu Arg Val Glu Gln Gln Ser Arg Leu Glu Gln Leu Ser Ala 
    530                 535                 540                 


Ala Glu Leu Gln Ser Arg Asn Gln Gly His Trp Ala Asp Trp Leu Gln 
545                 550                 555                 560 


Ala Tyr Arg Ala Arg Leu Asp Lys Asp Leu Glu Gly Ala Gly Asp Ala 
                565                 570                 575     


Ala Ala Trp Gln Ala Glu His Val Arg Val Met His Ala Asn Asn Pro 
            580                 585                 590         


Lys Tyr Val Leu Arg Asn Tyr Ile Ala Gln Asn Ala Ile Glu Ala Ala 
        595                 600                 605             


Glu Arg Gly Asp Phe Ser Glu Val Arg Arg Val Leu Lys Leu Leu Glu 
    610                 615                 620                 


Thr Pro Tyr His Cys Glu Ala Gly Ala Ala Thr Asp Ala Glu Ala Thr 
625                 630                 635                 640 


Glu Ala Asp Gly Ala Asp Gly Arg Gln Arg Ser Tyr Ser Ser Lys Pro 
                645                 650                 655     


Pro Leu Trp Ala Ala Glu Leu Cys Val Thr Ser Ser 
            660                 665             


<210>  1150
<211>  664
<212>  PRT
<213>  Human

<400>  1150

Met Ser Gly Val Arg Gly Leu Ser Arg Leu Leu Ser Ala Arg Arg Leu 
1               5                   10                  15      


Ala Leu Ala Lys Ala Trp Pro Thr Val Leu Gln Thr Gly Thr Arg Gly 
            20                  25                  30          


Phe His Phe Thr Val Asp Gly Asn Lys Arg Ala Ser Ala Lys Val Ser 
        35                  40                  45              


Asp Ser Ile Ser Ala Gln Tyr Pro Val Val Asp His Glu Phe Asp Ala 
    50                  55                  60                  


Val Val Val Gly Ala Gly Gly Ala Gly Leu Arg Ala Ala Phe Gly Leu 
65                  70                  75                  80  


Ser Glu Ala Gly Phe Asn Thr Ala Cys Val Thr Lys Leu Phe Pro Thr 
                85                  90                  95      


Arg Ser His Thr Val Ala Ala Gln Gly Gly Ile Asn Ala Ala Leu Gly 
            100                 105                 110         


Asn Met Glu Glu Asp Asn Trp Arg Trp His Phe Tyr Asp Thr Val Lys 
        115                 120                 125             


Gly Ser Asp Trp Leu Gly Asp Gln Asp Ala Ile His Tyr Met Thr Glu 
    130                 135                 140                 


Gln Ala Pro Ala Ala Val Val Glu Leu Glu Asn Tyr Gly Met Pro Phe 
145                 150                 155                 160 


Ser Arg Thr Glu Asp Gly Lys Ile Tyr Gln Arg Ala Phe Gly Gly Gln 
                165                 170                 175     


Ser Leu Lys Phe Gly Lys Gly Gly Gln Ala His Arg Cys Cys Cys Val 
            180                 185                 190         


Ala Asp Arg Thr Gly His Ser Leu Leu His Thr Leu Tyr Gly Arg Ser 
        195                 200                 205             


Leu Arg Tyr Asp Thr Ser Tyr Phe Val Glu Tyr Phe Ala Leu Asp Leu 
    210                 215                 220                 


Leu Met Glu Asn Gly Glu Cys Arg Gly Val Ile Ala Leu Cys Ile Glu 
225                 230                 235                 240 


Asp Gly Ser Ile His Arg Ile Arg Ala Lys Asn Thr Val Val Ala Thr 
                245                 250                 255     


Gly Gly Tyr Gly Arg Thr Tyr Phe Ser Cys Thr Ser Ala His Thr Ser 
            260                 265                 270         


Thr Gly Asp Gly Thr Ala Met Ile Thr Arg Ala Gly Leu Pro Cys Gln 
        275                 280                 285             


Asp Leu Glu Phe Val Gln Phe His Pro Thr Gly Ile Tyr Gly Ala Gly 
    290                 295                 300                 


Cys Leu Ile Thr Glu Gly Cys Arg Gly Glu Gly Gly Ile Leu Ile Asn 
305                 310                 315                 320 


Ser Gln Gly Glu Arg Phe Met Glu Arg Tyr Ala Pro Val Ala Lys Asp 
                325                 330                 335     


Leu Ala Ser Arg Asp Val Val Ser Arg Ser Met Thr Leu Glu Ile Arg 
            340                 345                 350         


Glu Gly Arg Gly Cys Gly Pro Glu Lys Asp His Val Tyr Leu Gln Leu 
        355                 360                 365             


His His Leu Pro Pro Glu Gln Leu Ala Thr Arg Leu Pro Gly Ile Ser 
    370                 375                 380                 


Glu Thr Ala Met Ile Phe Ala Gly Val Asp Val Thr Lys Glu Pro Ile 
385                 390                 395                 400 


Pro Val Leu Pro Thr Val His Tyr Asn Met Gly Gly Ile Pro Thr Asn 
                405                 410                 415     


Tyr Lys Gly Gln Val Leu Arg His Val Asn Gly Gln Asp Gln Ile Val 
            420                 425                 430         


Pro Gly Leu Tyr Ala Cys Gly Glu Ala Ala Cys Ala Ser Val His Gly 
        435                 440                 445             


Ala Asn Arg Leu Gly Ala Asn Ser Leu Leu Asp Leu Val Val Phe Gly 
    450                 455                 460                 


Arg Ala Cys Ala Leu Ser Ile Glu Glu Ser Cys Arg Pro Gly Asp Lys 
465                 470                 475                 480 


Val Pro Pro Ile Lys Pro Asn Ala Gly Glu Glu Ser Val Met Asn Leu 
                485                 490                 495     


Asp Lys Leu Arg Phe Ala Asp Gly Ser Ile Arg Thr Ser Glu Leu Arg 
            500                 505                 510         


Leu Ser Met Gln Lys Ser Met Gln Asn His Ala Ala Val Phe Arg Val 
        515                 520                 525             


Gly Ser Val Leu Gln Glu Gly Cys Gly Lys Ile Ser Lys Leu Tyr Gly 
    530                 535                 540                 


Asp Leu Lys His Leu Lys Thr Phe Asp Arg Gly Met Val Trp Asn Thr 
545                 550                 555                 560 


Asp Leu Val Glu Thr Leu Glu Leu Gln Asn Leu Met Leu Cys Ala Leu 
                565                 570                 575     


Gln Thr Ile Tyr Gly Ala Glu Ala Arg Lys Glu Ser Arg Gly Ala His 
            580                 585                 590         


Ala Arg Glu Asp Tyr Lys Val Arg Ile Asp Glu Tyr Asp Tyr Ser Lys 
        595                 600                 605             


Pro Ile Gln Gly Gln Gln Lys Lys Pro Phe Glu Glu His Trp Arg Lys 
    610                 615                 620                 


His Thr Leu Ser Tyr Val Asp Val Gly Thr Gly Lys Val Thr Leu Glu 
625                 630                 635                 640 


Tyr Arg Pro Val Ile Asp Lys Thr Leu Asn Glu Ala Asp Cys Ala Thr 
                645                 650                 655     


Val Pro Pro Ala Ile Arg Ser Tyr 
            660                 


<210>  1151
<211>  1092
<212>  PRT
<213>  Human

<400>  1151

Met Pro Cys Gly Phe Ser Pro Ser Pro Val Ala His His Leu Val Pro 
1               5                   10                  15      


Gly Pro Pro Asp Thr Pro Ala Gln Gln Leu Arg Cys Gly Trp Thr Val 
            20                  25                  30          


Gly Gly Trp Leu Leu Ser Leu Val Arg Gly Leu Leu Pro Cys Leu Pro 
        35                  40                  45              


Pro Gly Ala Arg Thr Ala Glu Gly Pro Ile Met Val Leu Ala Gly Pro 
    50                  55                  60                  


Leu Ala Val Ser Leu Leu Leu Pro Ser Leu Thr Leu Leu Val Ser His 
65                  70                  75                  80  


Leu Ser Ser Ser Gln Asp Val Ser Ser Glu Pro Ser Ser Glu Gln Gln 
                85                  90                  95      


Leu Cys Ala Leu Ser Lys His Pro Thr Val Ala Phe Glu Asp Leu Gln 
            100                 105                 110         


Pro Trp Val Ser Asn Phe Thr Tyr Pro Gly Ala Arg Asp Phe Ser Gln 
        115                 120                 125             


Leu Ala Leu Asp Pro Ser Gly Asn Gln Leu Ile Val Gly Ala Arg Asn 
    130                 135                 140                 


Tyr Leu Phe Arg Leu Ser Leu Ala Asn Val Ser Leu Leu Gln Ala Thr 
145                 150                 155                 160 


Glu Trp Ala Ser Ser Glu Asp Thr Arg Arg Ser Cys Gln Ser Lys Gly 
                165                 170                 175     


Lys Thr Glu Glu Glu Cys Gln Asn Tyr Val Arg Val Leu Ile Val Ala 
            180                 185                 190         


Gly Arg Lys Val Phe Met Cys Gly Thr Asn Ala Phe Ser Pro Met Cys 
        195                 200                 205             


Thr Ser Arg Gln Val Gly Asn Leu Ser Arg Thr Ile Glu Lys Ile Asn 
    210                 215                 220                 


Gly Val Ala Arg Cys Pro Tyr Asp Pro Arg His Asn Ser Thr Ala Val 
225                 230                 235                 240 


Ile Ser Ser Gln Gly Glu Leu Tyr Ala Ala Thr Val Ile Asp Phe Ser 
                245                 250                 255     


Gly Arg Asp Pro Ala Ile Tyr Arg Ser Leu Gly Ser Gly Pro Pro Leu 
            260                 265                 270         


Arg Thr Ala Gln Tyr Asn Ser Lys Trp Leu Asn Glu Pro Asn Phe Val 
        275                 280                 285             


Ala Ala Tyr Asp Ile Gly Leu Phe Ala Tyr Phe Phe Leu Arg Glu Asn 
    290                 295                 300                 


Ala Val Glu His Asp Cys Gly Arg Thr Val Tyr Ser Arg Val Ala Arg 
305                 310                 315                 320 


Val Cys Lys Asn Asp Val Gly Gly Arg Phe Leu Leu Glu Asp Thr Trp 
                325                 330                 335     


Thr Thr Phe Met Lys Ala Arg Leu Asn Cys Ser Arg Pro Gly Glu Val 
            340                 345                 350         


Pro Phe Tyr Tyr Asn Glu Leu Gln Ser Ala Phe His Leu Pro Glu Gln 
        355                 360                 365             


Asp Leu Ile Tyr Gly Val Phe Thr Thr Asn Val Asn Ser Ile Ala Ala 
    370                 375                 380                 


Ser Ala Val Cys Ala Phe Asn Leu Ser Ala Ile Ser Gln Ala Phe Asn 
385                 390                 395                 400 


Gly Pro Phe Arg Tyr Gln Glu Asn Pro Arg Ala Ala Trp Leu Pro Ile 
                405                 410                 415     


Ala Asn Pro Ile Pro Asn Phe Gln Cys Gly Thr Leu Pro Glu Thr Gly 
            420                 425                 430         


Pro Asn Glu Asn Leu Thr Glu Arg Ser Leu Gln Asp Ala Gln Arg Leu 
        435                 440                 445             


Phe Leu Met Ser Glu Ala Val Gln Pro Val Thr Pro Glu Pro Cys Val 
    450                 455                 460                 


Thr Gln Asp Ser Val Arg Phe Ser His Leu Val Val Asp Leu Val Gln 
465                 470                 475                 480 


Ala Lys Asp Thr Leu Tyr His Val Leu Tyr Ile Gly Thr Glu Ser Gly 
                485                 490                 495     


Thr Ile Leu Lys Ala Leu Ser Thr Ala Ser Arg Ser Leu His Gly Cys 
            500                 505                 510         


Tyr Leu Glu Glu Leu His Val Leu Pro Pro Gly Arg Arg Glu Pro Leu 
        515                 520                 525             


Arg Ser Leu Arg Ile Leu His Ser Ala Arg Ala Leu Phe Val Gly Leu 
    530                 535                 540                 


Arg Asp Gly Val Leu Arg Val Pro Leu Glu Arg Cys Ala Ala Tyr Arg 
545                 550                 555                 560 


Ser Gln Gly Ala Cys Leu Gly Ala Arg Asp Pro Tyr Cys Gly Trp Asp 
                565                 570                 575     


Gly Lys Gln Gln Arg Cys Ser Thr Leu Glu Asp Ser Ser Asn Met Ser 
            580                 585                 590         


Leu Trp Thr Gln Asn Ile Thr Ala Cys Pro Val Arg Asn Val Thr Arg 
        595                 600                 605             


Asp Gly Gly Phe Gly Pro Trp Ser Pro Trp Gln Pro Cys Glu His Leu 
    610                 615                 620                 


Asp Gly Asp Asn Ser Gly Ser Cys Leu Cys Arg Ala Arg Ser Cys Asp 
625                 630                 635                 640 


Ser Pro Arg Pro Arg Cys Gly Gly Leu Asp Cys Leu Gly Pro Ala Ile 
                645                 650                 655     


His Ile Ala Asn Cys Ser Arg Asn Gly Ala Trp Thr Pro Trp Ser Ser 
            660                 665                 670         


Trp Ala Leu Cys Ser Thr Ser Cys Gly Ile Gly Phe Gln Val Arg Gln 
        675                 680                 685             


Arg Ser Cys Ser Asn Pro Ala Pro Arg His Gly Gly Arg Ile Phe Val 
    690                 695                 700                 


Gly Lys Ser Arg Glu Glu Arg Phe Cys Asn Glu Asn Thr Pro Cys Pro 
705                 710                 715                 720 


Val Pro Ile Phe Trp Ala Ser Trp Gly Ser Trp Ser Lys Cys Ser Ser 
                725                 730                 735     


Asn Cys Gly Gly Gly Met Gln Ser Arg Arg Arg Ala Cys Glu Asn Gly 
            740                 745                 750         


Asn Ser Cys Leu Gly Cys Gly Glu Phe Lys Thr Cys Asn Pro Glu Gly 
        755                 760                 765             


Cys Pro Glu Val Arg Arg Asn Thr Pro Trp Thr Pro Trp Leu Pro Val 
    770                 775                 780                 


Asn Val Thr Gln Gly Gly Ala Arg Gln Glu Gln Arg Phe Arg Phe Thr 
785                 790                 795                 800 


Cys Arg Ala Pro Leu Ala Asp Pro His Gly Leu Gln Phe Gly Arg Arg 
                805                 810                 815     


Arg Thr Glu Thr Arg Thr Cys Pro Ala Asp Gly Ser Gly Ser Cys Asp 
            820                 825                 830         


Thr Asp Ala Leu Val Glu Val Leu Leu Arg Ser Gly Ser Thr Ser Pro 
        835                 840                 845             


His Thr Val Ser Gly Gly Trp Ala Ala Trp Gly Pro Trp Ser Ser Cys 
    850                 855                 860                 


Ser Arg Asp Cys Glu Leu Gly Phe Arg Val Arg Lys Arg Thr Cys Thr 
865                 870                 875                 880 


Asn Pro Glu Pro Arg Asn Gly Gly Leu Pro Cys Val Gly Asp Ala Ala 
                885                 890                 895     


Glu Tyr Gln Asp Cys Asn Pro Gln Ala Cys Pro Val Arg Gly Ala Trp 
            900                 905                 910         


Ser Cys Trp Thr Ser Trp Ser Pro Cys Ser Ala Ser Cys Gly Gly Gly 
        915                 920                 925             


His Tyr Gln Arg Thr Arg Ser Cys Thr Ser Pro Ala Pro Ser Pro Gly 
    930                 935                 940                 


Glu Asp Ile Cys Leu Gly Leu His Thr Glu Glu Ala Leu Cys Ala Thr 
945                 950                 955                 960 


Gln Ala Cys Pro Gly Trp Ser Pro Trp Ser Glu Trp Ser Lys Cys Thr 
                965                 970                 975     


Asp Asp Gly Ala Gln Ser Arg Ser Arg His Cys Glu Glu Leu Leu Pro 
            980                 985                 990         


Gly Ser Ser Ala Cys Ala Gly Asn  Ser Ser Gln Ser Arg  Pro Cys Pro 
        995                 1000                 1005             


Tyr Ser  Glu Ile Pro Val Ile  Leu Pro Ala Ser Ser  Met Glu Glu 
    1010                 1015                 1020             


Ala Thr  Asp Cys Ala Gly Lys  Arg Asn Arg Thr Tyr  Leu Met Leu 
    1025                 1030                 1035             


Arg Ser  Ser Gln Pro Ser Ser  Thr Pro Leu Gln Ser  Leu Asp Ser 
    1040                 1045                 1050             


Phe His  Ile Leu Leu Gln Thr  Ala Lys Leu Cys Trp  Gly Pro His 
    1055                 1060                 1065             


Cys Phe  Glu Met Gly Ser Ile  Ser Ser Thr Trp Trp  Pro Arg Ala 
    1070                 1075                 1080             


Ser Pro  Ala Ser Trp Ala Leu  Gly Ser 
    1085                 1090         


<210>  1152
<211>  589
<212>  PRT
<213>  Human

<400>  1152

Met Tyr Arg Trp Leu Val Arg Ile Leu Gly Thr Ile Phe Arg Phe Cys 
1               5                   10                  15      


Asp Arg Ser Val Pro Pro Ala Arg Ala Leu Leu Lys Arg Arg Arg Ser 
            20                  25                  30          


Asp Ser Thr Leu Phe Ser Thr Val Asp Thr Asp Glu Ile Pro Ala Lys 
        35                  40                  45              


Arg Pro Arg Leu Asp Cys Phe Ile His Gln Val Lys Asn Ser Leu Tyr 
    50                  55                  60                  


Asn Ala Ala Ser Leu Phe Gly Phe Pro Phe Gln Leu Thr Thr Lys Pro 
65                  70                  75                  80  


Met Val Thr Ser Ala Cys Asn Gly Thr Arg Asn Val Ala Pro Ser Gly 
                85                  90                  95      


Glu Val Phe Ser Asn Ser Ser Ser Cys Glu Leu Thr Gly Ser Gly Ser 
            100                 105                 110         


Trp Asn Asn Met Leu Lys Leu Gly Asn Lys Ser Pro Asn Gly Ile Ser 
        115                 120                 125             


Asp Tyr Pro Lys Ile Arg Val Thr Val Thr Arg Asp Gln Pro Arg Arg 
    130                 135                 140                 


Val Leu Pro Ser Phe Gly Phe Thr Leu Asn Ser Glu Gly Cys Asn Arg 
145                 150                 155                 160 


Arg Pro Gly Gly Arg Arg His Ser Lys Gly Asn Pro Glu Ser Ser Leu 
                165                 170                 175     


Met Trp Lys Pro Gln Glu Gln Ala Val Thr Glu Met Ile Ser Glu Glu 
            180                 185                 190         


Ser Gly Lys Gly Leu Arg Arg Pro His Cys Thr Val Glu Glu Gly Val 
        195                 200                 205             


Gln Lys Glu Glu Arg Glu Lys Tyr Arg Lys Leu Leu Glu Arg Leu Lys 
    210                 215                 220                 


Glu Ser Gly His Gly Asn Ser Val Cys Pro Val Thr Ser Asn Tyr His 
225                 230                 235                 240 


Ser Ser Gln Arg Ser Gln Met Asp Thr Leu Lys Thr Lys Gly Trp Gly 
                245                 250                 255     


Glu Glu Gln Asn His Gly Val Lys Thr Thr Gln Phe Val Pro Lys Gln 
            260                 265                 270         


Tyr Arg Leu Val Glu Thr Arg Gly Pro Leu Cys Ser Leu Arg Ser Glu 
        275                 280                 285             


Lys Arg Cys Ser Lys Gly Lys Ile Thr Asp Thr Glu Thr Met Val Gly 
    290                 295                 300                 


Ile Arg Phe Glu Asn Glu Ser Arg Arg Gly Tyr Gln Leu Glu Pro Asp 
305                 310                 315                 320 


Leu Ser Glu Glu Val Ser Ala Arg Leu Arg Leu Gly Ser Gly Ser Asn 
                325                 330                 335     


Gly Leu Leu Arg Arg Lys Val Ser Ile Ile Glu Thr Lys Glu Lys Asn 
            340                 345                 350         


Cys Ser Gly Lys Glu Arg Asp Arg Arg Thr Asp Asp Leu Leu Glu Leu 
        355                 360                 365             


Thr Glu Asp Met Glu Lys Glu Ile Ser Asn Ala Leu Gly His Gly Pro 
    370                 375                 380                 


Gln Asp Glu Ile Leu Ser Ser Ala Phe Lys Leu Arg Ile Thr Arg Gly 
385                 390                 395                 400 


Asp Ile Gln Thr Leu Lys Asn Tyr His Trp Leu Asn Asp Glu Val Ile 
                405                 410                 415     


Asn Phe Tyr Met Asn Leu Leu Val Glu Arg Asn Lys Lys Gln Gly Tyr 
            420                 425                 430         


Pro Ala Leu His Val Phe Ser Thr Phe Phe Tyr Pro Lys Leu Lys Ser 
        435                 440                 445             


Gly Gly Tyr Gln Ala Val Lys Arg Trp Thr Lys Gly Val Asn Leu Phe 
    450                 455                 460                 


Glu Gln Glu Ile Ile Leu Val Pro Ile His Arg Lys Val His Trp Ser 
465                 470                 475                 480 


Leu Val Val Ile Asp Leu Arg Lys Lys Cys Leu Lys Tyr Leu Asp Ser 
                485                 490                 495     


Met Gly Gln Lys Gly His Arg Ile Cys Glu Ile Leu Leu Gln Tyr Leu 
            500                 505                 510         


Gln Asp Glu Ser Lys Thr Lys Arg Asn Ser Asp Leu Asn Leu Leu Glu 
        515                 520                 525             


Trp Thr His His Ser Met Lys Pro His Glu Ile Pro Gln Gln Leu Asn 
    530                 535                 540                 


Gly Ser Asp Cys Gly Met Phe Thr Cys Lys Tyr Ala Asp Tyr Ile Ser 
545                 550                 555                 560 


Arg Asp Lys Pro Ile Thr Phe Thr Gln His Gln Met Pro Leu Phe Arg 
                565                 570                 575     


Lys Lys Met Val Trp Glu Ile Leu His Gln Gln Leu Leu 
            580                 585                 


<210>  1153
<211>  225
<212>  PRT
<213>  Human

<400>  1153

Met Asp Ile Arg Pro Asn His Thr Ile Tyr Ile Asn Asn Met Asn Asp 
1               5                   10                  15      


Lys Ile Lys Lys Glu Glu Leu Lys Arg Ser Leu Tyr Ala Leu Phe Ser 
            20                  25                  30          


Gln Phe Gly His Val Val Asp Ile Val Ala Leu Lys Thr Met Lys Met 
        35                  40                  45              


Arg Gly Gln Ala Phe Val Ile Phe Lys Glu Leu Gly Ser Ser Thr Asn 
    50                  55                  60                  


Ala Leu Arg Gln Leu Gln Gly Phe Pro Phe Tyr Gly Lys Pro Met Arg 
65                  70                  75                  80  


Ile Gln Tyr Ala Lys Thr Asp Ser Asp Ile Ile Ser Lys Met Arg Gly 
                85                  90                  95      


Thr Phe Ala Asp Lys Glu Lys Lys Lys Glu Lys Lys Lys Ala Lys Thr 
            100                 105                 110         


Val Glu Gln Thr Ala Thr Thr Thr Asn Lys Lys Pro Gly Gln Gly Thr 
        115                 120                 125             


Pro Asn Ser Ala Asn Thr Gln Gly Asn Ser Thr Pro Asn Pro Gln Val 
    130                 135                 140                 


Pro Asp Tyr Pro Pro Asn Tyr Ile Leu Phe Leu Asn Asn Leu Pro Glu 
145                 150                 155                 160 


Glu Thr Asn Glu Met Met Leu Ser Met Leu Phe Asn Gln Phe Pro Gly 
                165                 170                 175     


Phe Lys Glu Val Arg Leu Val Pro Gly Arg His Asp Ile Ala Phe Val 
            180                 185                 190         


Glu Phe Glu Asn Asp Gly Gln Ala Gly Ala Ala Arg Asp Ala Leu Gln 
        195                 200                 205             


Gly Phe Lys Ile Thr Pro Ser His Ala Met Lys Ile Thr Tyr Ala Lys 
    210                 215                 220                 


Lys 
225 


<210>  1154
<211>  404
<212>  PRT
<213>  Human

<400>  1154

Met Ala Ala Val Pro Glu Leu Leu Gln Gln Gln Glu Glu Asp Arg Ser 
1               5                   10                  15      


Lys Leu Arg Ser Val Ser Val Asp Leu Asn Val Asp Pro Ser Leu Gln 
            20                  25                  30          


Ile Asp Ile Pro Asp Ala Leu Ser Glu Arg Asp Lys Val Lys Phe Thr 
        35                  40                  45              


Val His Thr Lys Thr Thr Leu Pro Thr Phe Gln Ser Pro Glu Phe Ser 
    50                  55                  60                  


Val Thr Arg Gln His Glu Asp Phe Val Trp Leu His Asp Thr Leu Ile 
65                  70                  75                  80  


Glu Thr Thr Asp Tyr Ala Gly Leu Ile Ile Pro Pro Ala Pro Thr Lys 
                85                  90                  95      


Pro Asp Phe Asp Gly Pro Arg Glu Lys Met Gln Lys Leu Gly Glu Gly 
            100                 105                 110         


Glu Gly Ser Met Thr Lys Glu Glu Phe Ala Lys Met Lys Gln Glu Leu 
        115                 120                 125             


Glu Ala Glu Tyr Leu Ala Val Phe Lys Lys Thr Val Ser Ser His Glu 
    130                 135                 140                 


Val Phe Leu Gln Arg Leu Ser Ser His Pro Val Leu Ser Lys Asp Arg 
145                 150                 155                 160 


Asn Phe His Val Phe Leu Glu Tyr Asp Gln Asp Leu Ser Val Arg Arg 
                165                 170                 175     


Lys Asn Thr Lys Glu Met Phe Gly Gly Phe Phe Lys Ser Val Val Lys 
            180                 185                 190         


Ser Ala Asp Glu Val Leu Phe Thr Gly Val Lys Glu Val Asp Asp Phe 
        195                 200                 205             


Phe Glu Gln Glu Lys Asn Phe Leu Ile Asn Tyr Tyr Asn Arg Ile Lys 
    210                 215                 220                 


Asp Ser Cys Val Lys Ala Asp Lys Met Thr Arg Ser His Lys Asn Val 
225                 230                 235                 240 


Ala Asp Asp Tyr Ile His Thr Ala Ala Cys Leu His Ser Leu Ala Leu 
                245                 250                 255     


Glu Glu Pro Thr Val Ile Lys Lys Tyr Leu Leu Lys Val Ala Glu Leu 
            260                 265                 270         


Phe Glu Lys Leu Arg Lys Val Glu Gly Arg Val Ser Ser Asp Glu Asp 
        275                 280                 285             


Leu Lys Leu Thr Glu Leu Leu Arg Tyr Tyr Met Leu Asn Ile Glu Ala 
    290                 295                 300                 


Ala Lys Asp Leu Leu Tyr Arg Arg Thr Lys Ala Leu Ile Asp Tyr Glu 
305                 310                 315                 320 


Asn Ser Asn Lys Ala Leu Asp Lys Ala Arg Leu Lys Ser Lys Asp Val 
                325                 330                 335     


Lys Leu Ala Glu Ala His Gln Gln Glu Cys Cys Gln Lys Phe Glu Gln 
            340                 345                 350         


Leu Ser Glu Ser Ala Lys Glu Glu Leu Ile Asn Phe Lys Arg Lys Arg 
        355                 360                 365             


Val Ala Ala Phe Arg Lys Asn Leu Ile Glu Met Ser Glu Leu Glu Ile 
    370                 375                 380                 


Lys His Ala Arg Asn Asn Val Ser Leu Leu Gln Ser Cys Ile Asp Leu 
385                 390                 395                 400 


Phe Lys Asn Asn 
                


<210>  1155
<211>  225
<212>  PRT
<213>  Human

<400>  1155

Met Val Thr His Ser Lys Phe Pro Ala Ala Gly Met Ser Arg Pro Leu 
1               5                   10                  15      


Asp Thr Ser Leu Arg Leu Lys Thr Phe Ser Ser Lys Ser Glu Tyr Gln 
            20                  25                  30          


Leu Val Val Asn Ala Val Arg Lys Leu Gln Glu Ser Gly Phe Tyr Trp 
        35                  40                  45              


Ser Ala Val Thr Gly Gly Glu Ala Asn Leu Leu Leu Ser Ala Glu Pro 
    50                  55                  60                  


Ala Gly Thr Phe Leu Ile Arg Asp Ser Ser Asp Gln Arg His Phe Phe 
65                  70                  75                  80  


Thr Leu Ser Val Lys Thr Gln Ser Gly Thr Lys Asn Leu Arg Ile Gln 
                85                  90                  95      


Cys Glu Gly Gly Ser Phe Ser Leu Gln Ser Asp Pro Arg Ser Thr Gln 
            100                 105                 110         


Pro Val Pro Arg Phe Asp Cys Val Leu Lys Leu Val His His Tyr Met 
        115                 120                 125             


Pro Pro Pro Gly Ala Pro Ser Phe Pro Ser Pro Pro Thr Glu Pro Ser 
    130                 135                 140                 


Ser Glu Val Pro Glu Gln Pro Ser Ala Gln Pro Leu Pro Gly Ser Pro 
145                 150                 155                 160 


Pro Arg Arg Ala Tyr Tyr Ile Tyr Ser Gly Gly Glu Lys Ile Pro Leu 
                165                 170                 175     


Val Leu Ser Arg Pro Leu Ser Ser Asn Val Ala Thr Leu Gln His Leu 
            180                 185                 190         


Cys Arg Lys Thr Val Asn Gly His Leu Asp Ser Tyr Glu Lys Val Thr 
        195                 200                 205             


Gln Leu Pro Gly Pro Ile Arg Glu Phe Leu Asp Gln Tyr Asp Ala Pro 
    210                 215                 220                 


Leu 
225 


<210>  1156
<211>  149
<212>  PRT
<213>  Human

<400>  1156

Met Ala Ser Ser Asp Ile Gln Val Lys Glu Leu Glu Lys Arg Ala Ser 
1               5                   10                  15      


Gly Gln Ala Phe Glu Leu Ile Leu Ser Pro Arg Ser Lys Glu Ser Val 
            20                  25                  30          


Pro Glu Phe Pro Leu Ser Pro Pro Lys Lys Lys Asp Leu Ser Leu Glu 
        35                  40                  45              


Glu Ile Gln Lys Lys Leu Glu Ala Ala Glu Glu Arg Arg Lys Ser His 
    50                  55                  60                  


Glu Ala Glu Val Leu Lys Gln Leu Ala Glu Lys Arg Glu His Glu Lys 
65                  70                  75                  80  


Glu Val Leu Gln Lys Ala Ile Glu Glu Asn Asn Asn Phe Ser Lys Met 
                85                  90                  95      


Ala Glu Glu Lys Leu Thr His Lys Met Glu Ala Asn Lys Glu Asn Arg 
            100                 105                 110         


Glu Ala Gln Met Ala Ala Lys Leu Glu Arg Leu Arg Glu Lys Asp Lys 
        115                 120                 125             


His Ile Glu Glu Val Arg Lys Asn Lys Glu Ser Lys Asp Pro Ala Asp 
    130                 135                 140                 


Glu Thr Glu Ala Asp 
145                 


<210>  1157
<211>  216
<212>  PRT
<213>  Human

<400>  1157

Met Thr Leu Ala Ala Tyr Lys Glu Lys Met Lys Glu Leu Pro Leu Val 
1               5                   10                  15      


Ser Leu Phe Cys Ser Cys Phe Leu Ala Asp Pro Leu Asn Lys Ser Ser 
            20                  25                  30          


Tyr Lys Tyr Glu Gly Trp Cys Gly Arg Gln Cys Arg Arg Lys Asp Glu 
        35                  40                  45              


Ser Gln Arg Lys Asp Ser Ala Asp Trp Arg Glu Arg Arg Ala Gln Ala 
    50                  55                  60                  


Asp Thr Val Asp Leu Asn Trp Cys Val Ile Ser Asp Met Glu Val Ile 
65                  70                  75                  80  


Glu Leu Asn Lys Cys Thr Ser Gly Gln Ser Phe Glu Val Ile Leu Lys 
                85                  90                  95      


Pro Pro Ser Phe Asp Gly Val Pro Glu Phe Asn Ala Ser Leu Pro Arg 
            100                 105                 110         


Arg Arg Asp Pro Ser Leu Glu Glu Ile Gln Lys Lys Leu Glu Ala Ala 
        115                 120                 125             


Glu Glu Arg Arg Lys Tyr Gln Glu Ala Glu Leu Leu Lys His Leu Ala 
    130                 135                 140                 


Glu Lys Arg Glu His Glu Arg Glu Val Ile Gln Lys Ala Ile Glu Glu 
145                 150                 155                 160 


Asn Asn Asn Phe Ile Lys Met Ala Lys Glu Lys Leu Ala Gln Lys Met 
                165                 170                 175     


Glu Ser Asn Lys Glu Asn Arg Glu Ala His Leu Ala Ala Met Leu Glu 
            180                 185                 190         


Arg Leu Gln Glu Lys Asp Lys His Ala Glu Glu Val Arg Lys Asn Lys 
        195                 200                 205             


Glu Leu Lys Glu Glu Ala Ser Arg 
    210                 215     


<210>  1158
<211>  589
<212>  PRT
<213>  Human

<400>  1158

Met Lys Arg Val Arg Thr Glu Gln Ile Gln Met Ala Val Ser Cys Tyr 
1               5                   10                  15      


Leu Lys Arg Arg Gln Tyr Val Asp Ser Asp Gly Pro Leu Lys Gln Gly 
            20                  25                  30          


Leu Arg Leu Ser Gln Thr Ala Glu Glu Met Ala Ala Asn Leu Thr Val 
        35                  40                  45              


Gln Ser Glu Ser Gly Cys Ala Asn Ile Val Ser Ala Ala Pro Cys Gln 
    50                  55                  60                  


Ala Glu Pro Gln Gln Tyr Glu Val Gln Phe Gly Arg Leu Arg Asn Phe 
65                  70                  75                  80  


Leu Thr Asp Ser Asp Ser Gln His Ser His Glu Val Met Pro Leu Leu 
                85                  90                  95      


Tyr Pro Leu Phe Val Tyr Leu His Leu Asn Leu Val Gln Asn Ser Pro 
            100                 105                 110         


Lys Ser Thr Val Glu Ser Phe Tyr Ser Arg Phe His Gly Met Phe Leu 
        115                 120                 125             


Gln Asn Ala Ser Gln Lys Asp Val Ile Glu Gln Leu Gln Thr Thr Gln 
    130                 135                 140                 


Thr Ile Gln Asp Ile Leu Ser Asn Phe Lys Leu Arg Ala Phe Leu Asp 
145                 150                 155                 160 


Asn Lys Tyr Val Val Arg Leu Gln Glu Asp Ser Tyr Asn Tyr Leu Ile 
                165                 170                 175     


Arg Tyr Leu Gln Ser Asp Asn Asn Thr Ala Leu Cys Lys Val Leu Thr 
            180                 185                 190         


Leu His Ile His Leu Asp Val Gln Pro Ala Lys Arg Thr Asp Tyr Gln 
        195                 200                 205             


Leu Tyr Ala Ser Gly Ser Ser Ser Arg Ser Glu Asn Asn Gly Leu Glu 
    210                 215                 220                 


Pro Pro Asp Met Pro Ser Pro Ile Leu Gln Asn Glu Ala Ala Leu Glu 
225                 230                 235                 240 


Val Leu Gln Glu Ser Ile Lys Arg Val Lys Asp Gly Pro Pro Ser Leu 
                245                 250                 255     


Thr Thr Ile Cys Phe Tyr Ala Phe Tyr Asn Thr Glu Gln Leu Leu Asn 
            260                 265                 270         


Thr Ala Glu Ile Ser Pro Asp Ser Lys Leu Leu Ala Ala Gly Phe Asp 
        275                 280                 285             


Asn Ser Cys Ile Lys Leu Trp Ser Leu Arg Ser Lys Lys Leu Lys Ser 
    290                 295                 300                 


Glu Pro His Gln Val Asp Val Ser Arg Ile His Leu Ala Cys Asp Ile 
305                 310                 315                 320 


Leu Glu Glu Glu Asp Asp Glu Asp Asp Asn Ala Gly Thr Glu Met Lys 
                325                 330                 335     


Ile Leu Arg Gly His Cys Gly Pro Val Tyr Ser Thr Arg Phe Leu Ala 
            340                 345                 350         


Asp Ser Ser Gly Leu Leu Ser Cys Ser Glu Asp Met Ser Ile Arg Tyr 
        355                 360                 365             


Trp Asp Leu Gly Ser Phe Thr Asn Thr Val Leu Tyr Gln Gly His Ala 
    370                 375                 380                 


Tyr Pro Val Trp Asp Leu Asp Ile Ser Pro Tyr Ser Leu Tyr Phe Ala 
385                 390                 395                 400 


Ser Gly Ser His Asp Arg Thr Ala Arg Leu Trp Ser Phe Asp Arg Thr 
                405                 410                 415     


Tyr Pro Leu Arg Ile Tyr Ala Gly His Leu Ala Asp Val Asp Cys Val 
            420                 425                 430         


Lys Phe His Pro Asn Ser Asn Tyr Leu Ala Thr Gly Ser Thr Asp Lys 
        435                 440                 445             


Thr Val Arg Leu Trp Ser Ala Gln Gln Gly Asn Ser Val Arg Leu Phe 
    450                 455                 460                 


Thr Gly His Arg Gly Pro Val Leu Ser Leu Ala Phe Ser Pro Asn Gly 
465                 470                 475                 480 


Lys Tyr Leu Ala Ser Ala Gly Glu Asp Gln Arg Leu Lys Leu Trp Asp 
                485                 490                 495     


Leu Ala Ser Gly Thr Leu Tyr Lys Glu Leu Arg Gly His Thr Asp Asn 
            500                 505                 510         


Ile Thr Ser Leu Thr Phe Ser Pro Asp Ser Gly Leu Ile Ala Ser Ala 
        515                 520                 525             


Ser Met Asp Asn Ser Val Arg Val Trp Asp Ile Arg Asn Thr Tyr Cys 
    530                 535                 540                 


Ser Ala Pro Ala Asp Gly Ser Ser Ser Glu Leu Val Gly Val Tyr Thr 
545                 550                 555                 560 


Gly Gln Met Ser Asn Val Leu Ser Val Gln Phe Met Ala Cys Asn Leu 
                565                 570                 575     


Leu Leu Val Thr Gly Ile Thr Gln Glu Asn Gln Glu His 
            580                 585                 


<210>  1159
<211>  215
<212>  PRT
<213>  Human

<400>  1159

Met Glu Lys Leu Tyr Ser Glu Asn Glu Gly Met Ala Ser Asn Gln Gly 
1               5                   10                  15      


Lys Met Glu Asn Glu Glu Gln Pro Gln Asp Glu Arg Lys Pro Glu Val 
            20                  25                  30          


Thr Cys Thr Leu Glu Asp Lys Lys Leu Glu Asn Glu Gly Lys Thr Glu 
        35                  40                  45              


Asn Lys Gly Lys Thr Gly Asp Glu Glu Met Leu Lys Asp Lys Gly Lys 
    50                  55                  60                  


Pro Glu Ser Glu Gly Glu Ala Lys Glu Gly Lys Ser Glu Arg Glu Gly 
65                  70                  75                  80  


Glu Ser Glu Met Glu Gly Gly Ser Glu Arg Glu Gly Lys Pro Glu Ile 
                85                  90                  95      


Glu Gly Lys Pro Glu Ser Glu Gly Glu Pro Gly Ser Glu Thr Arg Ala 
            100                 105                 110         


Ala Gly Lys Arg Pro Ala Glu Asp Asp Val Pro Arg Lys Ala Lys Arg 
        115                 120                 125             


Lys Thr Asn Lys Gly Leu Ala His Tyr Leu Lys Glu Tyr Lys Glu Ala 
    130                 135                 140                 


Ile His Asp Met Asn Phe Ser Asn Glu Asp Met Ile Arg Glu Phe Asp 
145                 150                 155                 160 


Asn Met Ala Lys Val Gln Asp Glu Lys Arg Lys Ser Lys Gln Lys Leu 
                165                 170                 175     


Gly Ala Phe Leu Trp Met Gln Arg Asn Leu Gln Asp Pro Phe Tyr Pro 
            180                 185                 190         


Arg Gly Pro Arg Glu Phe Arg Gly Gly Cys Arg Ala Pro Arg Arg Asp 
        195                 200                 205             


Ile Glu Asp Ile Pro Tyr Val 
    210                 215 


<210>  1160
<211>  476
<212>  PRT
<213>  Human

<400>  1160

Met Ala Phe Gly Lys Ser His Arg Asp Pro Tyr Ala Thr Ser Val Gly 
1               5                   10                  15      


His Leu Ile Glu Lys Ala Thr Phe Ala Gly Val Gln Thr Glu Asp Trp 
            20                  25                  30          


Gly Gln Phe Met His Ile Cys Asp Ile Ile Asn Thr Thr Gln Asp Gly 
        35                  40                  45              


Pro Lys Asp Ala Val Lys Ala Leu Lys Lys Arg Ile Ser Lys Asn Tyr 
    50                  55                  60                  


Asn His Lys Glu Ile Gln Leu Thr Leu Ser Leu Ile Asp Met Cys Val 
65                  70                  75                  80  


Gln Asn Cys Gly Pro Ser Phe Gln Ser Leu Ile Val Lys Lys Glu Phe 
                85                  90                  95      


Val Lys Glu Asn Leu Val Lys Leu Leu Asn Pro Arg Tyr Asn Leu Pro 
            100                 105                 110         


Leu Asp Ile Gln Asn Arg Ile Leu Asn Phe Ile Lys Thr Trp Ser Gln 
        115                 120                 125             


Gly Phe Pro Gly Gly Val Asp Val Ser Glu Val Lys Glu Val Tyr Leu 
    130                 135                 140                 


Asp Leu Val Lys Lys Gly Val Gln Phe Pro Pro Ser Glu Ala Glu Ala 
145                 150                 155                 160 


Glu Thr Ala Arg Gln Glu Thr Ala Gln Ile Ser Ser Asn Pro Pro Thr 
                165                 170                 175     


Ser Val Pro Thr Ala Pro Ala Leu Ser Ser Val Ile Ala Pro Lys Asn 
            180                 185                 190         


Ser Thr Val Thr Leu Val Pro Glu Gln Ile Gly Lys Leu His Ser Glu 
        195                 200                 205             


Leu Asp Met Val Lys Met Asn Val Arg Val Met Ser Ala Ile Leu Met 
    210                 215                 220                 


Glu Asn Thr Pro Gly Ser Glu Asn His Glu Asp Ile Glu Leu Leu Gln 
225                 230                 235                 240 


Lys Leu Tyr Lys Thr Gly Arg Glu Met Gln Glu Arg Ile Met Asp Leu 
                245                 250                 255     


Leu Val Val Val Glu Asn Glu Asp Val Thr Val Glu Leu Ile Gln Val 
            260                 265                 270         


Asn Glu Asp Leu Asn Asn Ala Ile Leu Gly Tyr Glu Arg Phe Thr Arg 
        275                 280                 285             


Asn Gln Gln Arg Ile Leu Glu Gln Asn Lys Asn Gln Lys Glu Ala Thr 
    290                 295                 300                 


Asn Thr Thr Ser Glu Pro Ser Ala Pro Ser Gln Asp Leu Leu Asp Leu 
305                 310                 315                 320 


Ser Pro Ser Pro Arg Met Pro Arg Ala Thr Leu Gly Glu Leu Asn Thr 
                325                 330                 335     


Met Asn Asn Gln Leu Ser Gly Leu Asn Phe Ser Leu Pro Ser Ser Asp 
            340                 345                 350         


Val Thr Asn Asn Leu Lys Pro Ser Leu His Pro Gln Met Asn Leu Leu 
        355                 360                 365             


Ala Leu Glu Asn Thr Glu Ile Pro Pro Phe Ala Gln Arg Thr Ser Gln 
    370                 375                 380                 


Asn Leu Thr Ser Ser His Ala Tyr Asp Asn Phe Leu Glu His Ser Asn 
385                 390                 395                 400 


Ser Val Phe Leu Gln Pro Val Ser Leu Gln Thr Ile Ala Ala Ala Pro 
                405                 410                 415     


Ser Asn Gln Ser Leu Pro Pro Leu Pro Ser Asn His Pro Ala Met Thr 
            420                 425                 430         


Lys Ser Asp Leu Gln Pro Pro Asn Tyr Tyr Glu Val Met Glu Phe Asp 
        435                 440                 445             


Pro Leu Ala Pro Ala Val Thr Thr Glu Ala Ile Tyr Glu Glu Ile Asp 
    450                 455                 460                 


Ala His Gln His Lys Gly Ala Gln Asn Asp Gly Asp 
465                 470                 475     


<210>  1161
<211>  747
<212>  PRT
<213>  Human

<400>  1161

Met Ser Gln Val Lys Ser Ser Tyr Ser Tyr Asp Ala Pro Ser Asp Phe 
1               5                   10                  15      


Ile Asn Phe Ser Ser Leu Asp Asp Glu Gly Asp Thr Gln Asn Ile Asp 
            20                  25                  30          


Ser Trp Phe Glu Glu Lys Ala Asn Leu Glu Asn Lys Leu Leu Gly Lys 
        35                  40                  45              


Asn Gly Thr Gly Gly Leu Phe Gln Gly Lys Thr Pro Leu Arg Lys Ala 
    50                  55                  60                  


Asn Leu Gln Gln Ala Ile Val Thr Pro Leu Lys Pro Val Asp Asn Thr 
65                  70                  75                  80  


Tyr Tyr Lys Glu Ala Glu Lys Glu Asn Leu Val Glu Gln Ser Ile Pro 
                85                  90                  95      


Ser Asn Ala Cys Ser Ser Leu Glu Val Glu Ala Ala Ile Ser Arg Lys 
            100                 105                 110         


Thr Pro Ala Gln Pro Gln Arg Arg Ser Leu Arg Leu Ser Ala Gln Lys 
        115                 120                 125             


Asp Leu Glu Gln Lys Glu Lys His His Val Lys Met Lys Ala Lys Arg 
    130                 135                 140                 


Cys Ala Thr Pro Val Ile Ile Asp Glu Ile Leu Pro Ser Lys Lys Met 
145                 150                 155                 160 


Lys Val Ser Asn Asn Lys Lys Lys Pro Glu Glu Glu Gly Ser Ala His 
                165                 170                 175     


Gln Asp Thr Ala Glu Lys Asn Ala Ser Ser Pro Glu Lys Ala Lys Gly 
            180                 185                 190         


Arg His Thr Val Pro Cys Met Pro Pro Ala Lys Gln Lys Phe Leu Lys 
        195                 200                 205             


Ser Thr Glu Glu Gln Glu Leu Glu Lys Ser Met Lys Met Gln Gln Glu 
    210                 215                 220                 


Val Val Glu Met Arg Lys Lys Asn Glu Glu Phe Lys Lys Leu Ala Leu 
225                 230                 235                 240 


Ala Gly Ile Gly Gln Pro Val Lys Lys Ser Val Ser Gln Val Thr Lys 
                245                 250                 255     


Ser Val Asp Phe His Phe Arg Thr Asp Glu Arg Ile Lys Gln His Pro 
            260                 265                 270         


Lys Asn Gln Glu Glu Tyr Lys Glu Val Asn Phe Thr Ser Glu Leu Arg 
        275                 280                 285             


Lys His Pro Ser Ser Pro Ala Arg Val Thr Lys Gly Cys Thr Ile Val 
    290                 295                 300                 


Lys Pro Phe Asn Leu Ser Gln Gly Lys Lys Arg Thr Phe Asp Glu Thr 
305                 310                 315                 320 


Val Ser Thr Tyr Val Pro Leu Ala Gln Gln Val Glu Asp Phe His Lys 
                325                 330                 335     


Arg Thr Pro Asn Arg Tyr His Leu Arg Ser Lys Lys Asp Asp Ile Asn 
            340                 345                 350         


Leu Leu Pro Ser Lys Ser Ser Val Thr Lys Ile Cys Arg Asp Pro Gln 
        355                 360                 365             


Thr Pro Val Leu Gln Thr Lys His Arg Ala Arg Ala Val Thr Cys Lys 
    370                 375                 380                 


Ser Thr Ala Glu Leu Glu Ala Glu Glu Leu Glu Lys Leu Gln Gln Tyr 
385                 390                 395                 400 


Lys Phe Lys Ala Arg Glu Leu Asp Pro Arg Ile Leu Glu Gly Gly Pro 
                405                 410                 415     


Ile Leu Pro Lys Lys Pro Pro Val Lys Pro Pro Thr Glu Pro Ile Gly 
            420                 425                 430         


Phe Asp Leu Glu Ile Glu Lys Arg Ile Gln Glu Arg Glu Ser Lys Lys 
        435                 440                 445             


Lys Thr Glu Asp Glu His Phe Glu Phe His Ser Arg Pro Cys Pro Thr 
    450                 455                 460                 


Lys Ile Leu Glu Asp Val Val Gly Val Pro Glu Lys Lys Val Leu Pro 
465                 470                 475                 480 


Ile Thr Val Pro Lys Ser Pro Ala Phe Ala Leu Lys Asn Arg Ile Arg 
                485                 490                 495     


Met Pro Thr Lys Glu Asp Glu Glu Glu Asp Glu Pro Val Val Ile Lys 
            500                 505                 510         


Ala Gln Pro Val Pro His Tyr Gly Val Pro Phe Lys Pro Gln Ile Pro 
        515                 520                 525             


Glu Ala Arg Thr Val Glu Ile Cys Pro Phe Ser Phe Asp Ser Arg Asp 
    530                 535                 540                 


Lys Glu Arg Gln Leu Gln Lys Glu Lys Lys Ile Lys Glu Leu Gln Lys 
545                 550                 555                 560 


Gly Glu Val Pro Lys Phe Lys Ala Leu Pro Leu Pro His Phe Asp Thr 
                565                 570                 575     


Ile Asn Leu Pro Glu Lys Lys Val Lys Asn Val Thr Gln Ile Glu Pro 
            580                 585                 590         


Phe Cys Leu Glu Thr Asp Arg Arg Gly Ala Leu Lys Ala Gln Thr Trp 
        595                 600                 605             


Lys His Gln Leu Glu Glu Glu Leu Arg Gln Gln Lys Glu Ala Ala Cys 
    610                 615                 620                 


Phe Lys Ala Arg Pro Asn Thr Val Ile Ser Gln Glu Pro Phe Val Pro 
625                 630                 635                 640 


Lys Lys Glu Lys Lys Ser Val Ala Glu Gly Leu Ser Gly Ser Leu Val 
                645                 650                 655     


Gln Glu Pro Phe Gln Leu Ala Thr Glu Lys Arg Ala Lys Glu Arg Gln 
            660                 665                 670         


Glu Leu Glu Lys Arg Met Ala Glu Val Glu Ala Gln Lys Ala Gln Gln 
        675                 680                 685             


Leu Glu Glu Ala Arg Leu Gln Glu Glu Glu Gln Lys Lys Glu Glu Leu 
    690                 695                 700                 


Ala Arg Leu Arg Arg Glu Leu Val His Lys Ala Asn Pro Ile Arg Lys 
705                 710                 715                 720 


Tyr Gln Gly Leu Glu Ile Lys Ser Ser Asp Gln Pro Leu Thr Val Pro 
                725                 730                 735     


Val Ser Pro Lys Phe Ser Thr Arg Phe His Cys 
            740                 745         


<210>  1162
<211>  362
<212>  PRT
<213>  Human

<400>  1162

Met Glu Leu Gly Ser Cys Leu Glu Gly Gly Arg Glu Ala Ala Glu Glu 
1               5                   10                  15      


Glu Gly Glu Pro Glu Val Lys Lys Arg Arg Leu Leu Cys Val Glu Phe 
            20                  25                  30          


Ala Ser Val Ala Ser Cys Asp Ala Ala Val Ala Gln Cys Phe Leu Ala 
        35                  40                  45              


Glu Asn Asp Trp Glu Met Glu Arg Ala Leu Asn Ser Tyr Phe Glu Pro 
    50                  55                  60                  


Pro Val Glu Glu Ser Ala Leu Glu Arg Arg Pro Glu Thr Ile Ser Glu 
65                  70                  75                  80  


Pro Lys Thr Tyr Val Asp Leu Thr Asn Glu Glu Thr Thr Asp Ser Thr 
                85                  90                  95      


Thr Ser Lys Ile Ser Pro Ser Glu Asp Thr Gln Gln Glu Asn Gly Ser 
            100                 105                 110         


Met Phe Ser Leu Ile Thr Trp Asn Ile Asp Gly Leu Asp Leu Asn Asn 
        115                 120                 125             


Leu Ser Glu Arg Ala Arg Gly Val Cys Ser Tyr Leu Ala Leu Tyr Ser 
    130                 135                 140                 


Pro Asp Val Ile Phe Leu Gln Glu Val Ile Pro Pro Tyr Tyr Ser Tyr 
145                 150                 155                 160 


Leu Lys Lys Arg Ser Ser Asn Tyr Glu Ile Ile Thr Gly His Glu Glu 
                165                 170                 175     


Gly Tyr Phe Thr Ala Ile Met Leu Lys Lys Ser Arg Val Lys Leu Lys 
            180                 185                 190         


Ser Gln Glu Ile Ile Pro Phe Pro Ser Thr Lys Met Met Arg Asn Leu 
        195                 200                 205             


Leu Cys Val His Val Asn Val Ser Gly Asn Glu Leu Cys Leu Met Thr 
    210                 215                 220                 


Ser His Leu Glu Ser Thr Arg Gly His Ala Ala Glu Arg Met Asn Gln 
225                 230                 235                 240 


Leu Lys Met Val Leu Lys Lys Met Gln Glu Ala Pro Glu Ser Ala Thr 
                245                 250                 255     


Val Ile Phe Ala Gly Asp Thr Asn Leu Arg Asp Arg Glu Val Thr Arg 
            260                 265                 270         


Cys Gly Gly Leu Pro Asn Asn Ile Val Asp Val Trp Glu Phe Leu Gly 
        275                 280                 285             


Lys Pro Lys His Cys Gln Tyr Thr Trp Asp Thr Gln Met Asn Ser Asn 
    290                 295                 300                 


Leu Gly Ile Thr Ala Ala Cys Lys Leu Arg Phe Asp Arg Ile Phe Phe 
305                 310                 315                 320 


Arg Ala Ala Ala Glu Glu Gly His Ile Ile Pro Arg Ser Leu Asp Leu 
                325                 330                 335     


Leu Gly Leu Glu Lys Leu Asp Cys Gly Arg Phe Pro Ser Asp His Trp 
            340                 345                 350         


Gly Leu Leu Cys Asn Leu Asp Ile Ile Leu 
        355                 360         


<210>  1163
<211>  962
<212>  PRT
<213>  Human

<400>  1163

Met Asn Phe Leu Arg Gly Val Met Gly Gly Gln Ser Ala Gly Pro Gln 
1               5                   10                  15      


His Thr Glu Ala Glu Thr Ile Gln Lys Leu Cys Asp Arg Val Ala Ser 
            20                  25                  30          


Ser Thr Leu Leu Asp Asp Arg Arg Asn Ala Val Arg Ala Leu Lys Ser 
        35                  40                  45              


Leu Ser Lys Lys Tyr Arg Leu Glu Val Gly Ile Gln Ala Met Glu His 
    50                  55                  60                  


Leu Ile His Val Leu Gln Thr Asp Arg Ser Asp Ser Glu Ile Ile Gly 
65                  70                  75                  80  


Tyr Ala Leu Asp Ile Leu Tyr Asn Ile Ile Ser Asn Glu Glu Glu Glu 
                85                  90                  95      


Glu Val Glu Glu Asn Ser Thr Arg Gln Ser Glu Asp Leu Gly Ser Gln 
            100                 105                 110         


Phe Thr Glu Ile Phe Ile Lys Gln Gln Glu Asn Val Thr Leu Leu Leu 
        115                 120                 125             


Ser Leu Leu Glu Glu Phe Asp Phe His Val Arg Trp Pro Gly Val Lys 
    130                 135                 140                 


Leu Leu Thr Ser Leu Leu Lys Gln Leu Gly Pro Gln Val Gln Gln Ile 
145                 150                 155                 160 


Ile Leu Val Ser Pro Met Gly Val Ser Arg Leu Met Asp Leu Leu Ala 
                165                 170                 175     


Asp Ser Arg Glu Val Ile Arg Asn Asp Gly Val Leu Leu Leu Gln Ala 
            180                 185                 190         


Leu Thr Arg Ser Asn Gly Ala Ile Gln Lys Ile Val Ala Phe Glu Asn 
        195                 200                 205             


Ala Phe Glu Arg Leu Leu Asp Ile Ile Ser Glu Glu Gly Asn Ser Asp 
    210                 215                 220                 


Gly Gly Ile Val Val Glu Asp Cys Leu Ile Leu Leu Gln Asn Leu Leu 
225                 230                 235                 240 


Lys Asn Asn Asn Ser Asn Gln Asn Phe Phe Lys Glu Gly Ser Tyr Ile 
                245                 250                 255     


Gln Arg Met Lys Pro Trp Phe Glu Val Gly Asp Glu Asn Ser Gly Trp 
            260                 265                 270         


Ser Ala Gln Lys Val Thr Asn Leu His Leu Met Leu Gln Leu Val Arg 
        275                 280                 285             


Val Leu Val Ser Pro Thr Asn Pro Pro Gly Ala Thr Ser Ser Cys Gln 
    290                 295                 300                 


Lys Ala Met Phe Gln Cys Gly Leu Leu Gln Gln Leu Cys Thr Ile Leu 
305                 310                 315                 320 


Met Ala Thr Gly Val Pro Ala Asp Ile Leu Thr Glu Thr Ile Asn Thr 
                325                 330                 335     


Val Ser Glu Val Ile Arg Gly Cys Gln Val Asn Gln Asp Tyr Phe Ala 
            340                 345                 350         


Ser Val Asn Ala Pro Ser Asn Pro Pro Arg Pro Ala Ile Val Val Leu 
        355                 360                 365             


Leu Met Ser Met Val Asn Glu Arg Gln Pro Phe Val Leu Arg Cys Ala 
    370                 375                 380                 


Val Leu Tyr Cys Phe Gln Cys Phe Leu Tyr Lys Asn Gln Lys Gly Gln 
385                 390                 395                 400 


Gly Glu Ile Val Ser Thr Leu Leu Pro Ser Thr Ile Asp Ala Thr Gly 
                405                 410                 415     


Asn Ser Val Ser Ala Gly Gln Leu Leu Cys Gly Gly Leu Phe Ser Thr 
            420                 425                 430         


Asp Ser Leu Ser Asn Trp Cys Ala Ala Val Ala Leu Ala His Ala Leu 
        435                 440                 445             


Gln Glu Asn Ala Thr Gln Lys Glu Gln Leu Leu Arg Val Gln Leu Ala 
    450                 455                 460                 


Thr Ser Ile Gly Asn Pro Pro Val Ser Leu Leu Gln Gln Cys Thr Asn 
465                 470                 475                 480 


Ile Leu Ser Gln Gly Ser Lys Ile Gln Thr Arg Val Gly Leu Leu Met 
                485                 490                 495     


Leu Leu Cys Thr Trp Leu Ser Asn Cys Pro Ile Ala Val Thr His Phe 
            500                 505                 510         


Leu His Asn Ser Ala Asn Val Pro Phe Leu Thr Gly Gln Ile Ala Glu 
        515                 520                 525             


Asn Leu Gly Glu Glu Glu Gln Leu Val Gln Gly Leu Cys Ala Leu Leu 
    530                 535                 540                 


Leu Gly Ile Ser Ile Tyr Phe Asn Asp Asn Ser Leu Glu Ser Tyr Met 
545                 550                 555                 560 


Lys Glu Lys Leu Lys Gln Leu Ile Glu Lys Arg Ile Gly Lys Glu Asn 
                565                 570                 575     


Phe Ile Glu Lys Leu Gly Phe Ile Ser Lys His Glu Leu Tyr Ser Arg 
            580                 585                 590         


Ala Ser Gln Lys Pro Gln Pro Asn Phe Pro Ser Pro Glu Tyr Met Ile 
        595                 600                 605             


Phe Asp His Glu Phe Thr Lys Leu Val Lys Glu Leu Glu Gly Val Ile 
    610                 615                 620                 


Thr Lys Ala Ile Tyr Lys Ser Ser Glu Glu Asp Lys Lys Glu Glu Glu 
625                 630                 635                 640 


Val Lys Lys Thr Leu Glu Gln His Asp Asn Ile Val Thr His Tyr Lys 
                645                 650                 655     


Asn Met Ile Arg Glu Gln Asp Leu Gln Leu Glu Glu Leu Arg Gln Gln 
            660                 665                 670         


Val Ser Thr Leu Lys Cys Gln Asn Glu Gln Leu Gln Thr Ala Val Thr 
        675                 680                 685             


Gln Gln Val Ser Gln Ile Gln Gln His Lys Asp Gln Tyr Asn Leu Leu 
    690                 695                 700                 


Lys Ile Gln Leu Gly Lys Asp Asn Gln His Gln Gly Ser Tyr Ser Glu 
705                 710                 715                 720 


Gly Ala Gln Met Asn Gly Ile Gln Pro Glu Glu Ile Gly Arg Leu Arg 
                725                 730                 735     


Glu Glu Ile Glu Glu Leu Lys Arg Asn Gln Glu Leu Leu Gln Ser Gln 
            740                 745                 750         


Leu Thr Glu Lys Asp Ser Met Ile Glu Asn Met Lys Ser Ser Gln Thr 
        755                 760                 765             


Ser Gly Thr Asn Glu Gln Ser Ser Ala Ile Val Ser Ala Arg Asp Ser 
    770                 775                 780                 


Glu Gln Val Ala Glu Leu Lys Gln Glu Leu Ala Thr Leu Lys Ser Gln 
785                 790                 795                 800 


Leu Asn Ser Gln Ser Val Glu Ile Thr Lys Leu Gln Thr Glu Lys Gln 
                805                 810                 815     


Glu Leu Leu Gln Lys Thr Glu Ala Phe Ala Lys Ser Val Glu Val Gln 
            820                 825                 830         


Gly Glu Thr Glu Thr Ile Ile Ala Thr Lys Thr Thr Asp Val Glu Gly 
        835                 840                 845             


Arg Leu Ser Ala Leu Leu Gln Glu Thr Lys Glu Leu Lys Asn Glu Ile 
    850                 855                 860                 


Lys Ala Leu Ser Glu Glu Arg Thr Ala Ile Lys Glu Gln Leu Asp Ser 
865                 870                 875                 880 


Ser Asn Ser Thr Ile Ala Ile Leu Gln Thr Glu Lys Asp Lys Leu Glu 
                885                 890                 895     


Leu Glu Ile Thr Asp Ser Lys Lys Glu Gln Asp Asp Leu Leu Val Leu 
            900                 905                 910         


Leu Ala Asp Gln Asp Gln Lys Ile Leu Ser Leu Lys Asn Lys Leu Lys 
        915                 920                 925             


Asp Leu Gly His Pro Val Glu Glu Glu Asp Glu Leu Glu Ser Gly Asp 
    930                 935                 940                 


Gln Glu Asp Glu Asp Asp Glu Ser Glu Asp Pro Gly Lys Asp Leu Asp 
945                 950                 955                 960 


His Ile 
        


<210>  1164
<211>  1318
<212>  PRT
<213>  Human

<400>  1164

Met Ser Gly Gly Ala Ser Ala Thr Gly Pro Arg Arg Gly Pro Pro Gly 
1               5                   10                  15      


Leu Glu Asp Thr Thr Ser Lys Lys Lys Gln Lys Asp Arg Ala Asn Gln 
            20                  25                  30          


Glu Ser Lys Asp Gly Asp Pro Arg Lys Glu Thr Gly Ser Arg Tyr Val 
        35                  40                  45              


Ala Gln Ala Gly Leu Glu Pro Leu Ala Ser Gly Asp Pro Ser Ala Ser 
    50                  55                  60                  


Ala Ser His Ala Ala Gly Ile Thr Gly Ser Arg His Arg Thr Arg Leu 
65                  70                  75                  80  


Phe Phe Pro Ser Ser Ser Gly Ser Ala Ser Thr Pro Gln Glu Glu Gln 
                85                  90                  95      


Thr Lys Glu Gly Ala Cys Glu Asp Pro His Asp Leu Leu Ala Thr Pro 
            100                 105                 110         


Thr Pro Glu Leu Leu Leu Asp Trp Arg Gln Ser Ala Glu Glu Val Ile 
        115                 120                 125             


Val Lys Leu Arg Val Gly Val Gly Pro Leu Gln Leu Glu Asp Val Asp 
    130                 135                 140                 


Ala Ala Phe Thr Asp Thr Asp Cys Val Val Arg Phe Ala Gly Gly Gln 
145                 150                 155                 160 


Gln Trp Gly Gly Val Phe Tyr Ala Glu Ile Lys Ser Ser Cys Ala Lys 
                165                 170                 175     


Val Gln Thr Arg Lys Gly Ser Leu Leu His Leu Thr Leu Pro Lys Lys 
            180                 185                 190         


Val Pro Met Leu Thr Trp Pro Ser Leu Leu Val Glu Ala Asp Glu Gln 
        195                 200                 205             


Leu Cys Ile Pro Pro Leu Asn Ser Gln Thr Cys Leu Leu Gly Ser Glu 
    210                 215                 220                 


Glu Asn Leu Ala Pro Leu Ala Gly Glu Lys Ala Val Pro Pro Gly Asn 
225                 230                 235                 240 


Asp Pro Val Ser Pro Ala Met Val Arg Ser Arg Asn Pro Gly Lys Asp 
                245                 250                 255     


Asp Cys Ala Lys Glu Glu Met Ala Val Ala Ala Asp Ala Ala Thr Leu 
            260                 265                 270         


Val Asp Glu Pro Glu Ser Met Val Asn Leu Ala Phe Val Lys Asn Asp 
        275                 280                 285             


Ser Tyr Glu Lys Gly Pro Asp Ser Val Val Val His Val Tyr Val Lys 
    290                 295                 300                 


Glu Ile Cys Arg Asp Thr Ser Arg Val Leu Phe Arg Glu Gln Asp Phe 
305                 310                 315                 320 


Thr Leu Ile Phe Gln Thr Arg Asp Gly Asn Phe Leu Arg Leu His Pro 
                325                 330                 335     


Gly Cys Gly Pro His Thr Thr Phe Arg Trp Gln Val Lys Leu Arg Asn 
            340                 345                 350         


Leu Ile Glu Pro Glu Gln Cys Thr Phe Cys Phe Thr Ala Ser Arg Ile 
        355                 360                 365             


Asp Ile Cys Leu Arg Lys Arg Gln Ser Gln Arg Trp Gly Gly Leu Glu 
    370                 375                 380                 


Ala Pro Ala Ala Arg Val Gly Gly Ala Lys Val Ala Val Pro Thr Gly 
385                 390                 395                 400 


Pro Thr Pro Leu Asp Ser Thr Pro Pro Gly Gly Ala Pro His Pro Leu 
                405                 410                 415     


Thr Gly Gln Glu Glu Ala Arg Ala Val Glu Lys Asp Lys Ser Lys Ala 
            420                 425                 430         


Arg Ser Glu Asp Thr Gly Leu Asp Ser Val Ala Thr Arg Thr Pro Met 
        435                 440                 445             


Glu His Val Thr Pro Lys Pro Glu Thr His Leu Ala Ser Pro Lys Pro 
    450                 455                 460                 


Thr Cys Met Val Pro Pro Met Pro His Ser Pro Val Ser Gly Asp Ser 
465                 470                 475                 480 


Val Glu Glu Glu Glu Glu Glu Glu Lys Lys Val Cys Leu Pro Gly Phe 
                485                 490                 495     


Thr Gly Leu Val Asn Leu Gly Asn Thr Cys Phe Met Asn Ser Val Ile 
            500                 505                 510         


Gln Ser Leu Ser Asn Thr Arg Glu Leu Arg Asp Phe Phe His Asp Arg 
        515                 520                 525             


Ser Phe Glu Ala Glu Ile Asn Tyr Asn Asn Pro Leu Gly Thr Gly Gly 
    530                 535                 540                 


Arg Leu Ala Ile Gly Phe Ala Val Leu Leu Arg Ala Leu Trp Lys Gly 
545                 550                 555                 560 


Thr His His Ala Phe Gln Pro Ser Lys Leu Lys Ala Ile Val Ala Ser 
                565                 570                 575     


Lys Ala Ser Gln Phe Thr Gly Tyr Ala Gln His Asp Ala Gln Glu Phe 
            580                 585                 590         


Met Ala Phe Leu Leu Asp Gly Leu His Glu Asp Leu Asn Arg Ile Gln 
        595                 600                 605             


Asn Lys Pro Tyr Thr Glu Thr Val Asp Ser Asp Gly Arg Pro Asp Glu 
    610                 615                 620                 


Val Val Ala Glu Glu Ala Trp Gln Arg His Lys Met Arg Asn Asp Ser 
625                 630                 635                 640 


Phe Ile Val Asp Leu Phe Gln Gly Gln Tyr Lys Ser Lys Leu Val Cys 
                645                 650                 655     


Pro Val Cys Ala Lys Val Ser Ile Thr Phe Asp Pro Phe Leu Tyr Leu 
            660                 665                 670         


Pro Val Pro Leu Pro Gln Lys Gln Lys Val Leu Pro Val Phe Tyr Phe 
        675                 680                 685             


Ala Arg Glu Pro His Ser Lys Pro Ile Lys Phe Leu Val Ser Val Ser 
    690                 695                 700                 


Lys Glu Asn Ser Thr Ala Ser Glu Val Leu Asp Ser Leu Ser Gln Ser 
705                 710                 715                 720 


Val His Val Lys Pro Glu Asn Leu Arg Leu Ala Glu Val Ile Lys Asn 
                725                 730                 735     


Arg Phe His Arg Val Phe Leu Pro Ser His Ser Leu Asp Thr Val Ser 
            740                 745                 750         


Pro Ser Asp Thr Leu Leu Cys Phe Glu Leu Leu Ser Ser Glu Leu Ala 
        755                 760                 765             


Lys Glu Arg Val Val Val Leu Glu Val Gln Gln Arg Pro Gln Val Pro 
    770                 775                 780                 


Ser Val Pro Ile Ser Lys Cys Ala Ala Cys Gln Arg Lys Gln Gln Ser 
785                 790                 795                 800 


Glu Asp Glu Lys Leu Lys Arg Cys Thr Arg Cys Tyr Arg Val Gly Tyr 
                805                 810                 815     


Cys Asn Gln Leu Cys Gln Lys Thr His Trp Pro Asp His Lys Gly Leu 
            820                 825                 830         


Cys Arg Pro Glu Asn Ile Gly Tyr Pro Phe Leu Val Ser Val Pro Ala 
        835                 840                 845             


Ser Arg Leu Thr Tyr Ala Arg Leu Ala Gln Leu Leu Glu Gly Tyr Ala 
    850                 855                 860                 


Arg Tyr Ser Val Ser Val Phe Gln Pro Pro Phe Gln Pro Gly Arg Met 
865                 870                 875                 880 


Ala Leu Glu Ser Gln Ser Pro Gly Cys Thr Thr Leu Leu Ser Thr Gly 
                885                 890                 895     


Ser Leu Glu Ala Gly Asp Ser Glu Arg Asp Pro Ile Gln Pro Pro Glu 
            900                 905                 910         


Leu Gln Leu Val Thr Pro Met Ala Glu Gly Asp Thr Gly Leu Pro Arg 
        915                 920                 925             


Val Trp Ala Ala Pro Asp Arg Gly Pro Val Pro Ser Thr Ser Gly Ile 
    930                 935                 940                 


Ser Ser Glu Met Leu Ala Ser Gly Pro Ile Glu Val Gly Ser Leu Pro 
945                 950                 955                 960 


Ala Gly Glu Arg Val Ser Arg Pro Glu Ala Ala Val Pro Gly Tyr Gln 
                965                 970                 975     


His Pro Ser Glu Ala Met Asn Ala His Thr Pro Gln Phe Phe Ile Tyr 
            980                 985                 990         


Lys Ile Asp Ser Ser Asn Arg Glu  Gln Arg Leu Glu Asp  Lys Gly Asp 
        995                 1000                 1005             


Thr Pro  Leu Glu Leu Gly Asp  Asp Cys Ser Leu Ala  Leu Val Trp 
    1010                 1015                 1020             


Arg Asn  Asn Glu Arg Leu Gln  Glu Phe Val Leu Val  Ala Ser Lys 
    1025                 1030                 1035             


Glu Leu  Glu Cys Ala Glu Asp  Pro Gly Ser Ala Gly  Glu Ala Ala 
    1040                 1045                 1050             


Arg Ala  Gly His Phe Thr Leu  Asp Gln Cys Leu Asn  Leu Phe Thr 
    1055                 1060                 1065             


Arg Pro  Glu Val Leu Ala Pro  Glu Glu Ala Trp Tyr  Cys Pro Gln 
    1070                 1075                 1080             


Cys Lys  Gln His Arg Glu Ala  Ser Lys Gln Leu Leu  Leu Trp Arg 
    1085                 1090                 1095             


Leu Pro  Asn Val Leu Ile Val  Gln Leu Lys Arg Phe  Ser Phe Arg 
    1100                 1105                 1110             


Ser Phe  Ile Trp Arg Asp Lys  Ile Asn Asp Leu Val  Glu Phe Pro 
    1115                 1120                 1125             


Val Arg  Asn Leu Asp Leu Ser  Lys Phe Cys Ile Gly  Gln Lys Glu 
    1130                 1135                 1140             


Glu Gln  Leu Pro Ser Tyr Asp  Leu Tyr Ala Val Ile  Asn His Tyr 
    1145                 1150                 1155             


Gly Gly  Met Ile Gly Gly His  Tyr Thr Ala Cys Ala  Arg Leu Pro 
    1160                 1165                 1170             


Asn Asp  Arg Ser Ser Gln Arg  Ser Asp Val Gly Trp  Arg Leu Phe 
    1175                 1180                 1185             


Asp Asp  Ser Thr Val Thr Thr  Val Asp Glu Ser Gln  Val Val Thr 
    1190                 1195                 1200             


Arg Tyr  Ala Tyr Val Leu Phe  Tyr Arg Arg Arg Asn  Ser Pro Val 
    1205                 1210                 1215             


Glu Arg  Pro Pro Arg Ala Gly  His Ser Glu His His  Pro Asp Leu 
    1220                 1225                 1230             


Gly Pro  Ala Ala Glu Ala Ala  Ala Ser Gln Ala Ser  Arg Ile Trp 
    1235                 1240                 1245             


Gln Glu  Leu Glu Ala Glu Glu  Glu Pro Val Pro Glu  Gly Ser Gly 
    1250                 1255                 1260             


Pro Leu  Gly Pro Trp Gly Pro  Gln Asp Trp Val Gly  Pro Leu Pro 
    1265                 1270                 1275             


Arg Gly  Pro Thr Thr Pro Asp  Glu Gly Cys Leu Arg  Tyr Phe Val 
    1280                 1285                 1290             


Leu Gly  Thr Val Ala Ala Leu  Val Ala Leu Val Leu  Asn Val Phe 
    1295                 1300                 1305             


Tyr Pro  Leu Val Ser Gln Ser  Arg Trp Arg 
    1310                 1315             


<210>  1165
<211>  1055
<212>  PRT
<213>  Human

<400>  1165

Met Thr Val Glu Gln Asn Val Leu Gln Gln Ser Ala Ala Gln Lys His 
1               5                   10                  15      


Gln Gln Thr Phe Leu Asn Gln Leu Arg Glu Ile Thr Gly Ile Asn Asp 
            20                  25                  30          


Thr Gln Ile Leu Gln Gln Ala Leu Lys Asp Ser Asn Gly Asn Leu Glu 
        35                  40                  45              


Leu Ala Val Ala Phe Leu Thr Ala Lys Asn Ala Lys Thr Pro Gln Gln 
    50                  55                  60                  


Glu Glu Thr Thr Tyr Tyr Gln Thr Ala Leu Pro Gly Asn Asp Arg Tyr 
65                  70                  75                  80  


Ile Ser Val Gly Ser Gln Ala Asp Thr Asn Val Ile Asp Leu Thr Gly 
                85                  90                  95      


Asp Asp Lys Asp Asp Leu Gln Arg Ala Ile Ala Leu Ser Leu Ala Glu 
            100                 105                 110         


Ser Asn Arg Ala Phe Arg Glu Thr Gly Ile Thr Asp Glu Glu Gln Ala 
        115                 120                 125             


Ile Ser Arg Val Leu Glu Ala Ser Ile Ala Glu Asn Lys Ala Cys Leu 
    130                 135                 140                 


Lys Arg Thr Pro Thr Glu Val Trp Arg Asp Ser Arg Asn Pro Tyr Asp 
145                 150                 155                 160 


Arg Lys Arg Gln Asp Lys Ala Pro Val Gly Leu Lys Asn Val Gly Asn 
                165                 170                 175     


Thr Cys Trp Phe Ser Ala Val Ile Gln Ser Leu Phe Asn Leu Leu Glu 
            180                 185                 190         


Phe Arg Arg Leu Val Leu Asn Tyr Lys Pro Pro Ser Asn Ala Gln Asp 
        195                 200                 205             


Leu Pro Arg Asn Gln Lys Glu His Arg Asn Leu Pro Phe Met Arg Glu 
    210                 215                 220                 


Leu Arg Tyr Leu Phe Ala Leu Leu Val Gly Thr Lys Arg Lys Tyr Val 
225                 230                 235                 240 


Asp Pro Ser Arg Ala Val Glu Ile Leu Lys Asp Ala Phe Lys Ser Asn 
                245                 250                 255     


Asp Ser Gln Gln Gln Asp Val Ser Glu Phe Thr His Lys Leu Leu Asp 
            260                 265                 270         


Trp Leu Glu Asp Ala Phe Gln Met Lys Ala Glu Glu Glu Thr Asp Glu 
        275                 280                 285             


Glu Lys Pro Lys Asn Pro Met Val Glu Leu Phe Tyr Gly Arg Phe Leu 
    290                 295                 300                 


Ala Val Gly Val Leu Glu Gly Lys Lys Phe Glu Asn Thr Glu Met Phe 
305                 310                 315                 320 


Gly Gln Tyr Pro Leu Gln Val Asn Gly Phe Lys Asp Leu His Glu Cys 
                325                 330                 335     


Leu Glu Ala Ala Met Ile Glu Gly Glu Ile Glu Ser Leu His Ser Glu 
            340                 345                 350         


Asn Ser Gly Lys Ser Gly Gln Glu His Trp Phe Thr Glu Leu Pro Pro 
        355                 360                 365             


Val Leu Thr Phe Glu Leu Ser Arg Phe Glu Phe Asn Gln Ala Leu Gly 
    370                 375                 380                 


Arg Pro Glu Lys Ile His Asn Lys Leu Glu Phe Pro Gln Val Leu Tyr 
385                 390                 395                 400 


Leu Asp Arg Tyr Met His Arg Asn Arg Glu Ile Thr Arg Ile Lys Arg 
                405                 410                 415     


Glu Glu Ile Lys Arg Leu Lys Asp Tyr Leu Thr Val Leu Gln Gln Arg 
            420                 425                 430         


Leu Glu Arg Tyr Leu Ser Tyr Gly Ser Gly Pro Lys Arg Phe Pro Leu 
        435                 440                 445             


Val Asp Val Leu Gln Tyr Ala Leu Glu Phe Ala Ser Ser Lys Pro Val 
    450                 455                 460                 


Cys Thr Ser Pro Val Asp Asp Ile Asp Ala Ser Ser Pro Pro Ser Gly 
465                 470                 475                 480 


Ser Ile Pro Ser Gln Thr Leu Pro Ser Thr Thr Glu Gln Gln Gly Ala 
                485                 490                 495     


Leu Ser Ser Glu Leu Pro Ser Thr Ser Pro Ser Ser Val Ala Ala Ile 
            500                 505                 510         


Ser Ser Arg Ser Val Ile His Lys Pro Phe Thr Gln Ser Arg Ile Pro 
        515                 520                 525             


Pro Asp Leu Pro Met His Pro Ala Pro Arg His Ile Thr Glu Glu Glu 
    530                 535                 540                 


Leu Ser Val Leu Glu Ser Cys Leu His Arg Trp Arg Thr Glu Ile Glu 
545                 550                 555                 560 


Asn Asp Thr Arg Asp Leu Gln Glu Ser Ile Ser Arg Ile His Arg Thr 
                565                 570                 575     


Ile Glu Leu Met Tyr Ser Asp Lys Ser Met Ile Gln Val Pro Tyr Arg 
            580                 585                 590         


Leu His Ala Val Leu Val His Glu Gly Gln Ala Asn Ala Gly His Tyr 
        595                 600                 605             


Trp Ala Tyr Ile Phe Asp His Arg Glu Ser Arg Trp Met Lys Tyr Asn 
    610                 615                 620                 


Asp Ile Ala Val Thr Lys Ser Ser Trp Glu Glu Leu Val Arg Asp Ser 
625                 630                 635                 640 


Phe Gly Gly Tyr Arg Asn Ala Ser Ala Tyr Cys Leu Met Tyr Ile Asn 
                645                 650                 655     


Asp Lys Ala Gln Phe Leu Ile Gln Glu Glu Phe Asn Lys Glu Thr Gly 
            660                 665                 670         


Gln Pro Leu Val Gly Ile Glu Thr Leu Pro Pro Asp Leu Arg Asp Phe 
        675                 680                 685             


Val Glu Glu Asp Asn Gln Arg Phe Glu Lys Glu Leu Glu Glu Trp Asp 
    690                 695                 700                 


Ala Gln Leu Ala Gln Lys Ala Leu Gln Glu Lys Leu Leu Ala Ser Gln 
705                 710                 715                 720 


Lys Leu Arg Glu Ser Glu Thr Ser Val Thr Thr Ala Gln Ala Ala Gly 
                725                 730                 735     


Asp Pro Glu Tyr Leu Glu Gln Pro Ser Arg Ser Asp Phe Ser Lys His 
            740                 745                 750         


Leu Lys Glu Glu Thr Ile Gln Ile Ile Thr Lys Ala Ser His Glu His 
        755                 760                 765             


Glu Asp Lys Ser Pro Glu Thr Val Leu Gln Ser Ala Ile Lys Leu Glu 
    770                 775                 780                 


Tyr Ala Arg Leu Val Lys Leu Ala Gln Glu Asp Thr Pro Pro Glu Thr 
785                 790                 795                 800 


Asp Tyr Arg Leu His His Val Val Val Tyr Phe Ile Gln Asn Gln Ala 
                805                 810                 815     


Pro Lys Lys Ile Ile Glu Lys Thr Leu Leu Glu Gln Phe Gly Asp Arg 
            820                 825                 830         


Asn Leu Ser Phe Asp Glu Arg Cys His Asn Ile Met Lys Val Ala Gln 
        835                 840                 845             


Ala Lys Leu Glu Met Ile Lys Pro Glu Glu Val Asn Leu Glu Glu Tyr 
    850                 855                 860                 


Glu Glu Trp His Gln Asp Tyr Arg Lys Phe Arg Glu Thr Thr Met Tyr 
865                 870                 875                 880 


Leu Ile Ile Gly Leu Glu Asn Phe Gln Arg Glu Ser Tyr Ile Asp Ser 
                885                 890                 895     


Leu Leu Phe Leu Ile Cys Ala Tyr Gln Asn Asn Lys Glu Leu Leu Ser 
            900                 905                 910         


Lys Gly Leu Tyr Arg Gly His Asp Glu Glu Leu Ile Ser His Tyr Arg 
        915                 920                 925             


Arg Glu Cys Leu Leu Lys Leu Asn Glu Gln Ala Ala Glu Leu Phe Glu 
    930                 935                 940                 


Ser Gly Glu Asp Arg Glu Val Asn Asn Gly Leu Ile Ile Met Asn Glu 
945                 950                 955                 960 


Phe Ile Val Pro Phe Leu Pro Leu Leu Leu Val Asp Glu Met Glu Glu 
                965                 970                 975     


Lys Asp Ile Leu Ala Val Glu Asp Met Arg Asn Arg Trp Cys Ser Tyr 
            980                 985                 990         


Leu Gly Gln Glu Met Glu Pro His  Leu Gln Glu Lys Leu  Thr Asp Phe 
        995                 1000                 1005             


Leu Pro  Lys Leu Leu Asp Cys  Ser Met Glu Ile Lys  Ser Phe His 
    1010                 1015                 1020             


Glu Pro  Pro Lys Leu Pro Ser  Tyr Ser Thr His Glu  Leu Cys Glu 
    1025                 1030                 1035             


Arg Phe  Ala Arg Ile Met Leu  Ser Leu Ser Arg Thr  Pro Ala Asp 
    1040                 1045                 1050             


Gly Arg  
    1055 


<210>  1166
<211>  465
<212>  PRT
<213>  Human

<400>  1166

Met Thr Pro Val Arg Met Gln His Ser Leu Ala Gly Gln Thr Tyr Ala 
1               5                   10                  15      


Val Pro Leu Ile Gln Pro Asp Leu Arg Arg Glu Glu Ala Val Gln Gln 
            20                  25                  30          


Met Ala Asp Ala Leu Gln Tyr Leu Gln Lys Val Ser Gly Asp Ile Phe 
        35                  40                  45              


Ser Arg Ile Ser Gln Arg Val Glu Gln Ser Arg Ser Gln Val Gln Ala 
    50                  55                  60                  


Ile Gly Glu Lys Val Ser Leu Ala Gln Ala Lys Ile Glu Lys Ile Lys 
65                  70                  75                  80  


Gly Ser Lys Lys Ala Ile Lys Val Phe Ser Ser Ala Lys Tyr Pro Ala 
                85                  90                  95      


Pro Glu Arg Leu Gln Glu Tyr Gly Ser Ile Phe Thr Gly Ala Gln Asp 
            100                 105                 110         


Pro Gly Leu Gln Arg Arg Pro Arg His Arg Ile Gln Ser Lys His Arg 
        115                 120                 125             


Pro Leu Asp Glu Arg Ala Leu Gln Glu Lys Leu Lys Asp Phe Pro Val 
    130                 135                 140                 


Cys Val Ser Thr Lys Pro Glu Pro Glu Asp Asp Ala Glu Glu Gly Leu 
145                 150                 155                 160 


Gly Gly Leu Pro Ser Asn Ile Ser Ser Val Ser Ser Leu Leu Leu Phe 
                165                 170                 175     


Asn Thr Thr Glu Asn Leu Tyr Lys Lys Tyr Val Phe Leu Asp Pro Leu 
            180                 185                 190         


Ala Gly Ala Val Thr Lys Thr His Val Met Leu Gly Ala Glu Thr Glu 
        195                 200                 205             


Glu Lys Leu Phe Asp Ala Pro Leu Ser Ile Ser Lys Arg Glu Gln Leu 
    210                 215                 220                 


Glu Gln Gln Val Pro Glu Asn Tyr Phe Tyr Val Pro Asp Leu Gly Gln 
225                 230                 235                 240 


Val Pro Glu Ile Asp Val Pro Ser Tyr Leu Pro Asp Leu Pro Gly Ile 
                245                 250                 255     


Ala Asn Asp Leu Met Tyr Ser Ala Asp Leu Gly Pro Gly Ile Ala Pro 
            260                 265                 270         


Ser Ala Pro Gly Thr Ile Pro Glu Leu Pro Thr Phe His Thr Glu Val 
        275                 280                 285             


Ala Glu Pro Leu Lys Val Asp Leu Gln Asp Gly Val Leu Thr Pro Pro 
    290                 295                 300                 


Pro Pro Pro Pro Pro Pro Pro Pro Ala Pro Glu Val Leu Ala Ser Ala 
305                 310                 315                 320 


Pro Pro Leu Pro Pro Ser Thr Ala Ala Pro Val Gly Gln Gly Ala Arg 
                325                 330                 335     


Gln Asp Asp Ser Ser Ser Ser Ala Ser Pro Ser Val Gln Gly Ala Pro 
            340                 345                 350         


Arg Glu Val Val Asp Pro Ser Gly Gly Arg Ala Thr Leu Leu Glu Ser 
        355                 360                 365             


Ile Arg Gln Ala Gly Gly Ile Gly Lys Ala Lys Leu Arg Ser Val Lys 
    370                 375                 380                 


Glu Arg Lys Leu Glu Lys Lys Lys Gln Lys Glu Gln Glu Gln Val Arg 
385                 390                 395                 400 


Ala Thr Ser Gln Gly Gly Asp Leu Met Ser Asp Leu Phe Asn Lys Leu 
                405                 410                 415     


Val Met Arg Arg Lys Gly Ile Ser Gly Lys Gly Pro Gly Ala Gly Glu 
            420                 425                 430         


Gly Pro Gly Gly Ala Phe Ala Arg Val Ser Asp Ser Ile Pro Pro Leu 
        435                 440                 445             


Pro Pro Pro Gln Gln Pro Gln Ala Glu Glu Asp Glu Asp Asp Trp Glu 
    450                 455                 460                 


Ser 
465 


<210>  1167
<211>  504
<212>  PRT
<213>  Human

<400>  1167

Met Asp Pro Gly Gln Gln Pro Pro Pro Gln Pro Ala Pro Gln Gly Gln 
1               5                   10                  15      


Gly Gln Pro Pro Ser Gln Pro Pro Gln Gly Gln Gly Pro Pro Ser Gly 
            20                  25                  30          


Pro Gly Gln Pro Ala Pro Ala Ala Thr Gln Ala Ala Pro Gln Ala Pro 
        35                  40                  45              


Pro Ala Gly His Gln Ile Val His Val Arg Gly Asp Ser Glu Thr Asp 
    50                  55                  60                  


Leu Glu Ala Leu Phe Asn Ala Val Met Asn Pro Lys Thr Ala Asn Val 
65                  70                  75                  80  


Pro Gln Thr Val Pro Met Arg Leu Arg Lys Leu Pro Asp Ser Phe Phe 
                85                  90                  95      


Lys Pro Pro Glu Pro Lys Ser His Ser Arg Gln Ala Ser Thr Asp Ala 
            100                 105                 110         


Gly Thr Ala Gly Ala Leu Thr Pro Gln His Val Arg Ala His Ser Ser 
        115                 120                 125             


Pro Ala Ser Leu Gln Leu Gly Ala Val Ser Pro Gly Thr Leu Thr Pro 
    130                 135                 140                 


Thr Gly Val Val Ser Gly Pro Ala Ala Thr Pro Thr Ala Gln His Leu 
145                 150                 155                 160 


Arg Gln Ser Ser Phe Glu Ile Pro Asp Asp Val Pro Leu Pro Ala Gly 
                165                 170                 175     


Trp Glu Met Ala Lys Thr Ser Ser Gly Gln Arg Tyr Phe Leu Asn His 
            180                 185                 190         


Ile Asp Gln Thr Thr Thr Trp Gln Asp Pro Arg Lys Ala Met Leu Ser 
        195                 200                 205             


Gln Met Asn Val Thr Ala Pro Thr Ser Pro Pro Val Gln Gln Asn Met 
    210                 215                 220                 


Met Asn Ser Ala Ser Gly Pro Leu Pro Asp Gly Trp Glu Gln Ala Met 
225                 230                 235                 240 


Thr Gln Asp Gly Glu Ile Tyr Tyr Ile Asn His Lys Asn Lys Thr Thr 
                245                 250                 255     


Ser Trp Leu Asp Pro Arg Leu Asp Pro Arg Phe Ala Met Asn Gln Arg 
            260                 265                 270         


Ile Ser Gln Ser Ala Pro Val Lys Gln Pro Pro Pro Leu Ala Pro Gln 
        275                 280                 285             


Ser Pro Gln Gly Gly Val Met Gly Gly Ser Asn Ser Asn Gln Gln Gln 
    290                 295                 300                 


Gln Met Arg Leu Gln Gln Leu Gln Met Glu Lys Glu Arg Leu Arg Leu 
305                 310                 315                 320 


Lys Gln Gln Glu Leu Leu Arg Gln Ala Met Arg Asn Ile Asn Pro Ser 
                325                 330                 335     


Thr Ala Asn Ser Pro Lys Cys Gln Glu Leu Ala Leu Arg Ser Gln Leu 
            340                 345                 350         


Pro Thr Leu Glu Gln Asp Gly Gly Thr Gln Asn Pro Val Ser Ser Pro 
        355                 360                 365             


Gly Met Ser Gln Glu Leu Arg Thr Met Thr Thr Asn Ser Ser Asp Pro 
    370                 375                 380                 


Phe Leu Asn Ser Gly Thr Tyr His Ser Arg Asp Glu Ser Thr Asp Ser 
385                 390                 395                 400 


Gly Leu Ser Met Ser Ser Tyr Ser Val Pro Arg Thr Pro Asp Asp Phe 
                405                 410                 415     


Leu Asn Ser Val Asp Glu Met Asp Thr Gly Asp Thr Ile Asn Gln Ser 
            420                 425                 430         


Thr Leu Pro Ser Gln Gln Asn Arg Phe Pro Asp Tyr Leu Glu Ala Ile 
        435                 440                 445             


Pro Gly Thr Asn Val Asp Leu Gly Thr Leu Glu Gly Asp Gly Met Asn 
    450                 455                 460                 


Ile Glu Gly Glu Glu Leu Met Pro Ser Leu Gln Glu Ala Leu Ser Ser 
465                 470                 475                 480 


Asp Ile Leu Asn Asp Met Glu Ser Val Leu Ala Ala Thr Lys Leu Asp 
                485                 490                 495     


Lys Glu Ser Phe Leu Thr Trp Leu 
            500                 


<210>  1168
<211>  441
<212>  PRT
<213>  Human

<400>  1168

Met Glu Ile Ser Ser His Gln Ser His Leu Leu Gln Gln Leu Asn Glu 
1               5                   10                  15      


Gln Arg Arg Gln Asp Val Phe Cys Asp Cys Ser Ile Leu Val Glu Gly 
            20                  25                  30          


Lys Val Phe Lys Ala His Arg Asn Val Leu Phe Ala Ser Ser Gly Tyr 
        35                  40                  45              


Phe Lys Met Leu Leu Ser Gln Asn Ser Lys Glu Thr Ser Gln Pro Thr 
    50                  55                  60                  


Thr Ala Thr Phe Gln Ala Phe Ser Pro Asp Thr Phe Thr Val Ile Leu 
65                  70                  75                  80  


Asp Phe Val Tyr Ser Gly Lys Leu Ser Leu Thr Gly Gln Asn Val Ile 
                85                  90                  95      


Glu Val Met Ser Ala Ala Ser Phe Leu Gln Met Thr Asp Val Ile Ser 
            100                 105                 110         


Val Cys Lys Thr Phe Ile Lys Ser Ser Leu Asp Ile Ser Glu Lys Glu 
        115                 120                 125             


Lys Asp Arg Tyr Phe Ser Leu Ser Asp Lys Asp Ala Asn Ser Asn Gly 
    130                 135                 140                 


Val Glu Arg Ser Ser Phe Tyr Ser Gly Gly Trp Gln Glu Gly Ser Ser 
145                 150                 155                 160 


Ser Pro Arg Ser His Leu Ser Pro Glu Gln Gly Thr Gly Ile Ile Ser 
                165                 170                 175     


Gly Lys Ser Trp Asn Lys Tyr Asn Tyr His Pro Ala Ser Gln Lys Asn 
            180                 185                 190         


Thr Gln Gln Pro Leu Ala Lys His Glu Pro Arg Lys Glu Ser Ile Lys 
        195                 200                 205             


Lys Thr Lys His Leu Arg Leu Ser Gln Pro Ser Glu Val Thr His Tyr 
    210                 215                 220                 


Lys Ser Ser Lys Arg Glu Val Arg Thr Ser Asp Ser Ser Ser His Val 
225                 230                 235                 240 


Ser Gln Ser Glu Glu Gln Ala Gln Ile Asp Ala Glu Met Asp Ser Thr 
                245                 250                 255     


Pro Val Gly Tyr Gln Tyr Gly Gln Gly Ser Asp Val Thr Ser Lys Ser 
            260                 265                 270         


Phe Pro Asp Asp Leu Pro Arg Met Arg Phe Lys Cys Pro Tyr Cys Thr 
        275                 280                 285             


His Val Val Lys Arg Lys Ala Asp Leu Lys Arg His Leu Arg Cys His 
    290                 295                 300                 


Thr Gly Glu Arg Pro Tyr Pro Cys Gln Ala Cys Gly Lys Arg Phe Ser 
305                 310                 315                 320 


Arg Leu Asp His Leu Ser Ser His Phe Arg Thr Ile His Gln Ala Cys 
                325                 330                 335     


Lys Leu Ile Cys Arg Lys Cys Lys Arg His Val Thr Asp Leu Thr Gly 
            340                 345                 350         


Gln Val Val Gln Glu Gly Thr Arg Arg Tyr Arg Leu Cys Asn Glu Cys 
        355                 360                 365             


Leu Ala Glu Phe Gly Ile Asp Ser Leu Pro Ile Asp Leu Glu Ala Glu 
    370                 375                 380                 


Gln His Leu Met Ser Pro Ser Asp Gly Asp Lys Asp Ser Arg Trp His 
385                 390                 395                 400 


Leu Ser Glu Asp Glu Asn Arg Ser Tyr Val Glu Ile Val Glu Asp Gly 
                405                 410                 415     


Ser Gly Asp Leu Val Ile Gln Gln Val Asp Asp Ser Glu Glu Glu Glu 
            420                 425                 430         


Glu Lys Glu Ile Lys Pro Asn Ile Arg 
        435                 440     


<210>  1169
<211>  327
<212>  PRT
<213>  Human

<400>  1169

Met Glu Val Ala Val Pro Val Lys Gln Glu Ala Glu Gly Leu Ala Leu 
1               5                   10                  15      


Asp Ser Pro Trp His Arg Phe Arg Arg Phe His Leu Gly Asp Ala Pro 
            20                  25                  30          


Gly Pro Arg Glu Ala Leu Gly Leu Leu Arg Ala Leu Cys Arg Asp Trp 
        35                  40                  45              


Leu Arg Pro Glu Val His Thr Lys Glu Gln Met Leu Glu Leu Leu Val 
    50                  55                  60                  


Leu Glu Gln Phe Leu Ser Ala Leu Pro Ala Asp Thr Gln Ala Trp Val 
65                  70                  75                  80  


Cys Ser Arg Gln Pro Gln Ser Gly Glu Glu Ala Val Ala Leu Leu Glu 
                85                  90                  95      


Glu Leu Trp Gly Pro Ala Ala Ser Pro Asp Gly Ser Ser Ala Thr Arg 
            100                 105                 110         


Val Pro Gln Asp Val Thr Gln Gly Pro Gly Ala Thr Gly Gly Lys Glu 
        115                 120                 125             


Asp Ser Gly Met Ile Pro Leu Ala Gly Thr Ala Pro Gly Ala Glu Gly 
    130                 135                 140                 


Pro Ala Pro Gly Asp Ser Gln Ala Val Arg Pro Tyr Lys Gln Glu Pro 
145                 150                 155                 160 


Ser Ser Pro Pro Leu Ala Pro Gly Leu Pro Ala Phe Leu Ala Ala Pro 
                165                 170                 175     


Gly Thr Thr Ser Cys Pro Glu Cys Gly Lys Thr Ser Leu Lys Pro Ala 
            180                 185                 190         


His Leu Leu Arg His Arg Gln Ser His Ser Gly Glu Lys Pro His Ala 
        195                 200                 205             


Cys Pro Glu Cys Gly Lys Ala Phe Arg Arg Lys Glu His Leu Arg Arg 
    210                 215                 220                 


His Arg Asp Thr His Pro Gly Ser Pro Gly Ser Pro Gly Pro Ala Leu 
225                 230                 235                 240 


Arg Pro Leu Pro Ala Arg Glu Lys Pro His Ala Cys Cys Glu Cys Gly 
                245                 250                 255     


Lys Thr Phe Tyr Trp Arg Glu His Leu Val Arg His Arg Lys Thr His 
            260                 265                 270         


Ser Gly Ala Arg Pro Phe Ala Cys Trp Glu Cys Gly Lys Gly Phe Gly 
        275                 280                 285             


Arg Arg Glu His Val Leu Arg His Gln Arg Ile His Gly Arg Ala Ala 
    290                 295                 300                 


Ala Ser Ala Gln Gly Ala Val Ala Pro Gly Pro Asp Gly Gly Gly Pro 
305                 310                 315                 320 


Phe Pro Pro Trp Pro Leu Gly 
                325         


<210>  1170
<211>  822
<212>  PRT
<213>  Human

<400>  1170

Met Glu Glu Glu Glu Glu Ala Ile Gly Leu Leu Asp Lys Val Leu Glu 
1               5                   10                  15      


Asp Glu Asp Val Phe Leu Leu Glu Glu Cys Glu Leu Gly Thr Pro Thr 
            20                  25                  30          


Ser Pro Gly Ser Gly Ser Pro Phe Leu Val Ala Val Lys Val Glu Ala 
        35                  40                  45              


Gly Lys Gly Leu Glu Met Arg Lys Leu Val Leu Ser Gly Phe Leu Ala 
    50                  55                  60                  


Ser Glu Glu Ile Tyr Ile Asn Gln Leu Glu Ala Leu Leu Leu Pro Met 
65                  70                  75                  80  


Lys Pro Leu Lys Ala Thr Ala Thr Thr Ser Gln Pro Val Leu Thr Ile 
                85                  90                  95      


Gln Gln Ile Glu Thr Ile Phe Tyr Lys Ile Gln Asp Ile Tyr Glu Ile 
            100                 105                 110         


His Lys Glu Phe Tyr Asp Asn Leu Cys Pro Lys Val Gln Gln Trp Asp 
        115                 120                 125             


Ser Gln Val Thr Met Gly His Leu Phe Gln Lys Leu Ala Ser Gln Leu 
    130                 135                 140                 


Gly Val Tyr Lys Ala Phe Val Asp Asn Tyr Lys Val Ala Leu Glu Thr 
145                 150                 155                 160 


Ala Glu Lys Cys Ser Gln Ser Asn Asn Gln Phe Gln Lys Ile Ser Glu 
                165                 170                 175     


Glu Leu Lys Val Lys Gly Pro Lys Asp Ser Lys Asp Ser His Thr Ser 
            180                 185                 190         


Val Thr Met Glu Ala Leu Leu Tyr Lys Pro Ile Asp Arg Val Thr Arg 
        195                 200                 205             


Ser Thr Leu Val Leu His Asp Leu Leu Lys His Thr Pro Val Asp His 
    210                 215                 220                 


Pro Asp Tyr Pro Leu Leu Gln Asp Ala Leu Arg Ile Ser Gln Asn Phe 
225                 230                 235                 240 


Leu Ser Ser Ile Asn Glu Asp Ile Asp Pro Arg Arg Thr Ala Val Thr 
                245                 250                 255     


Thr Pro Lys Gly Glu Thr Arg Gln Leu Val Lys Asp Gly Phe Leu Val 
            260                 265                 270         


Glu Val Ser Glu Ser Ser Arg Lys Leu Arg His Val Phe Leu Phe Thr 
        275                 280                 285             


Asp Val Leu Leu Cys Ala Lys Leu Lys Lys Thr Ser Ala Gly Lys His 
    290                 295                 300                 


Gln Gln Tyr Asp Cys Lys Trp Tyr Ile Pro Leu Ala Asp Leu Val Phe 
305                 310                 315                 320 


Pro Ser Pro Glu Glu Ser Glu Ala Ser Pro Gln Val His Pro Phe Pro 
                325                 330                 335     


Asp His Glu Leu Glu Asp Met Lys Met Lys Ile Ser Ala Leu Lys Ser 
            340                 345                 350         


Glu Ile Gln Lys Glu Lys Ala Asn Lys Gly Gln Ser Arg Ala Ile Glu 
        355                 360                 365             


Arg Leu Lys Lys Lys Met Phe Glu Asn Glu Phe Leu Leu Leu Leu Asn 
    370                 375                 380                 


Ser Pro Thr Ile Pro Phe Arg Ile His Asn Arg Asn Gly Lys Ser Tyr 
385                 390                 395                 400 


Leu Phe Leu Leu Ser Ser Asp Tyr Glu Arg Ser Glu Trp Arg Glu Ala 
                405                 410                 415     


Ile Gln Lys Leu Gln Lys Lys Asp Leu Gln Ala Phe Val Leu Ser Ser 
            420                 425                 430         


Val Glu Leu Gln Val Leu Thr Gly Ser Cys Phe Lys Leu Arg Thr Val 
        435                 440                 445             


His Asn Ile Pro Val Thr Ser Asn Lys Asp Asp Asp Glu Ser Pro Gly 
    450                 455                 460                 


Leu Tyr Gly Phe Leu His Val Ile Val His Ser Ala Lys Gly Phe Lys 
465                 470                 475                 480 


Gln Ser Ala Asn Leu Tyr Cys Thr Leu Glu Val Asp Ser Phe Gly Tyr 
                485                 490                 495     


Phe Val Ser Lys Ala Lys Thr Arg Val Phe Arg Asp Thr Ala Glu Pro 
            500                 505                 510         


Lys Trp Asp Glu Glu Phe Glu Ile Glu Leu Glu Gly Ser Gln Ser Leu 
        515                 520                 525             


Arg Ile Leu Cys Tyr Glu Lys Cys Tyr Asp Lys Thr Lys Val Asn Lys 
    530                 535                 540                 


Asp Asn Asn Glu Ile Val Asp Lys Ile Met Gly Lys Gly Gln Ile Gln 
545                 550                 555                 560 


Leu Asp Pro Gln Thr Val Glu Thr Lys Asn Trp His Thr Asp Val Ile 
                565                 570                 575     


Glu Met Asn Gly Ile Lys Val Glu Phe Ser Met Lys Phe Thr Ser Arg 
            580                 585                 590         


Asp Met Ser Leu Lys Arg Thr Pro Ser Lys Lys Gln Thr Gly Val Phe 
        595                 600                 605             


Gly Val Lys Ile Ser Val Val Thr Lys Arg Glu Arg Ser Lys Val Pro 
    610                 615                 620                 


Tyr Ile Val Arg Gln Cys Val Glu Glu Val Glu Lys Arg Gly Ile Glu 
625                 630                 635                 640 


Glu Val Gly Ile Tyr Arg Ile Ser Gly Val Ala Thr Asp Ile Gln Ala 
                645                 650                 655     


Leu Lys Ala Val Phe Asp Ala Asn Asn Lys Asp Ile Leu Leu Met Leu 
            660                 665                 670         


Ser Asp Met Asp Ile Asn Ala Ile Ala Gly Thr Leu Lys Leu Tyr Phe 
        675                 680                 685             


Arg Glu Leu Pro Glu Pro Leu Leu Thr Asp Arg Leu Tyr Pro Ala Phe 
    690                 695                 700                 


Met Glu Gly Ile Ala Leu Ser Asp Pro Ala Ala Lys Glu Asn Cys Met 
705                 710                 715                 720 


Met His Leu Leu Arg Ser Leu Pro Asp Pro Asn Leu Ile Thr Phe Leu 
                725                 730                 735     


Phe Leu Leu Glu His Leu Lys Arg Val Ala Glu Lys Glu Pro Ile Asn 
            740                 745                 750         


Lys Met Ser Leu His Asn Leu Ala Thr Val Phe Gly Pro Thr Leu Leu 
        755                 760                 765             


Arg Pro Ser Glu Val Glu Ser Lys Ala His Leu Thr Ser Ala Ala Asp 
    770                 775                 780                 


Ile Trp Ser His Asp Val Met Ala Gln Val Gln Val Leu Leu Tyr Tyr 
785                 790                 795                 800 


Leu Gln His Pro Pro Ile Ser Phe Ala Glu Leu Lys Arg Asn Thr Leu 
                805                 810                 815     


Tyr Phe Ser Thr Asp Val 
            820         


<210>  1171
<211>  662
<212>  PRT
<213>  Human

<400>  1171

Met Asn Gly Asp Ser Arg Ala Ala Val Val Thr Ser Pro Pro Pro Thr 
1               5                   10                  15      


Thr Ala Pro His Lys Glu Arg Tyr Phe Asp Arg Val Asp Glu Asn Asn 
            20                  25                  30          


Pro Glu Tyr Leu Arg Glu Arg Asn Met Ala Pro Asp Leu Arg Gln Asp 
        35                  40                  45              


Phe Asn Met Met Glu Gln Lys Lys Arg Val Ser Met Ile Leu Gln Ser 
    50                  55                  60                  


Pro Ala Phe Cys Glu Glu Leu Glu Ser Met Ile Gln Glu Gln Phe Lys 
65                  70                  75                  80  


Lys Gly Lys Asn Pro Thr Gly Leu Leu Ala Leu Gln Gln Ile Ala Asp 
                85                  90                  95      


Phe Met Thr Thr Asn Val Pro Asn Val Tyr Pro Ala Ala Pro Gln Gly 
            100                 105                 110         


Gly Met Ala Ala Leu Asn Met Ser Leu Gly Met Val Thr Pro Val Asn 
        115                 120                 125             


Asp Leu Arg Gly Ser Asp Ser Ile Ala Tyr Asp Lys Gly Glu Lys Leu 
    130                 135                 140                 


Leu Arg Cys Lys Leu Ala Ala Phe Tyr Arg Leu Ala Asp Leu Phe Gly 
145                 150                 155                 160 


Trp Ser Gln Leu Ile Tyr Asn His Ile Thr Thr Arg Val Asn Ser Glu 
                165                 170                 175     


Gln Glu His Phe Leu Ile Val Pro Phe Gly Leu Leu Tyr Ser Glu Val 
            180                 185                 190         


Thr Ala Ser Ser Leu Val Lys Ile Asn Leu Gln Gly Asp Ile Val Asp 
        195                 200                 205             


Arg Gly Ser Thr Asn Leu Gly Val Asn Gln Ala Gly Phe Thr Leu His 
    210                 215                 220                 


Ser Ala Ile Tyr Ala Ala Arg Pro Asp Val Lys Cys Val Val His Ile 
225                 230                 235                 240 


His Thr Pro Ala Gly Ala Ala Val Ser Ala Met Lys Cys Gly Leu Leu 
                245                 250                 255     


Pro Ile Ser Pro Glu Ala Leu Ser Leu Gly Glu Val Ala Tyr His Asp 
            260                 265                 270         


Tyr His Gly Ile Leu Val Asp Glu Glu Glu Lys Val Leu Ile Gln Lys 
        275                 280                 285             


Asn Leu Gly Pro Lys Ser Lys Val Leu Ile Leu Arg Asn His Gly Leu 
    290                 295                 300                 


Val Ser Val Gly Glu Ser Val Glu Glu Ala Phe Tyr Tyr Ile His Asn 
305                 310                 315                 320 


Leu Val Val Ala Cys Glu Ile Gln Val Arg Thr Leu Ala Ser Ala Gly 
                325                 330                 335     


Gly Pro Asp Asn Leu Val Leu Leu Asn Pro Glu Lys Tyr Lys Ala Lys 
            340                 345                 350         


Ser Arg Ser Pro Gly Ser Pro Val Gly Glu Gly Thr Gly Ser Pro Pro 
        355                 360                 365             


Lys Trp Gln Ile Gly Glu Gln Glu Phe Glu Ala Leu Met Arg Met Leu 
    370                 375                 380                 


Asp Asn Leu Gly Tyr Arg Thr Gly Tyr Pro Tyr Arg Tyr Pro Ala Leu 
385                 390                 395                 400 


Arg Glu Lys Ser Lys Lys Tyr Ser Asp Val Glu Val Pro Ala Ser Val 
                405                 410                 415     


Thr Gly Tyr Ser Phe Ala Ser Asp Gly Asp Ser Gly Thr Cys Ser Pro 
            420                 425                 430         


Leu Arg His Ser Phe Gln Lys Gln Gln Arg Glu Lys Thr Arg Trp Leu 
        435                 440                 445             


Asn Ser Gly Arg Gly Asp Glu Ala Ser Glu Glu Gly Gln Asn Gly Ser 
    450                 455                 460                 


Ser Pro Lys Ser Lys Thr Lys Val Trp Thr Asn Ile Thr His Asp His 
465                 470                 475                 480 


Val Lys Pro Leu Leu Gln Ser Leu Ser Ser Gly Val Cys Val Pro Ser 
                485                 490                 495     


Cys Ile Thr Asn Cys Leu Trp Thr Lys Glu Asp Gly His Arg Thr Ser 
            500                 505                 510         


Thr Ser Ala Val Pro Asn Leu Phe Val Pro Leu Asn Thr Asn Pro Lys 
        515                 520                 525             


Glu Val Gln Glu Met Arg Asn Lys Ile Arg Glu Gln Asn Leu Gln Asp 
    530                 535                 540                 


Ile Lys Thr Ala Gly Pro Gln Ser Gln Val Leu Cys Gly Val Val Met 
545                 550                 555                 560 


Asp Arg Ser Leu Val Gln Gly Glu Leu Val Thr Ala Ser Lys Ala Ile 
                565                 570                 575     


Ile Glu Lys Glu Tyr Gln Pro His Val Ile Val Ser Thr Thr Gly Pro 
            580                 585                 590         


Asn Pro Phe Thr Thr Leu Thr Asp Arg Glu Leu Glu Glu Tyr Arg Arg 
        595                 600                 605             


Glu Val Glu Arg Lys Gln Lys Gly Ser Glu Glu Asn Leu Asp Glu Ala 
    610                 615                 620                 


Arg Glu Gln Lys Glu Lys Ser Pro Pro Asp Gln Pro Ala Val Pro His 
625                 630                 635                 640 


Pro Pro Pro Ser Thr Pro Ile Lys Leu Glu Glu Gly Asp Gly Cys Ala 
                645                 650                 655     


Arg Glu Tyr Leu Leu Pro 
            660         


<210>  1172
<211>  179
<212>  PRT
<213>  Human

<400>  1172

Met Val Gln Ala Trp Tyr Met Asp Asp Ala Pro Gly Asp Pro Arg Gln 
1               5                   10                  15      


Pro His Arg Pro Asp Pro Gly Arg Pro Val Gly Leu Glu Gln Leu Arg 
            20                  25                  30          


Arg Leu Gly Val Leu Tyr Trp Lys Leu Asp Ala Asp Lys Tyr Glu Asn 
        35                  40                  45              


Asp Pro Glu Leu Glu Lys Ile Arg Arg Glu Arg Asn Tyr Ser Trp Met 
    50                  55                  60                  


Asp Ile Ile Thr Ile Cys Lys Asp Lys Leu Pro Asn Tyr Glu Glu Lys 
65                  70                  75                  80  


Ile Lys Met Phe Tyr Glu Glu His Leu His Leu Asp Asp Glu Ile Arg 
                85                  90                  95      


Tyr Ile Leu Asp Gly Ser Gly Tyr Phe Asp Val Arg Asp Lys Glu Asp 
            100                 105                 110         


Gln Trp Ile Arg Ile Phe Met Glu Lys Gly Asp Met Val Thr Leu Pro 
        115                 120                 125             


Ala Gly Ile Tyr His Arg Phe Thr Val Asp Glu Lys Asn Tyr Thr Lys 
    130                 135                 140                 


Ala Met Arg Leu Phe Val Gly Glu Pro Val Trp Thr Ala Tyr Asn Arg 
145                 150                 155                 160 


Pro Ala Asp His Phe Glu Ala Arg Gly Gln Tyr Val Lys Phe Leu Ala 
                165                 170                 175     


Gln Thr Ala 
            


<210>  1173
<211>  312
<212>  PRT
<213>  Human

<400>  1173

Met Ala Asn Asn Asp Ala Val Leu Lys Arg Leu Glu Gln Lys Gly Ala 
1               5                   10                  15      


Glu Ala Asp Gln Ile Ile Glu Tyr Leu Lys Gln Gln Val Ser Leu Leu 
            20                  25                  30          


Lys Glu Lys Ala Ile Leu Gln Ala Thr Leu Arg Glu Glu Lys Lys Leu 
        35                  40                  45              


Arg Val Glu Asn Ala Lys Leu Lys Lys Glu Ile Glu Glu Leu Lys Gln 
    50                  55                  60                  


Glu Leu Ile Gln Ala Glu Ile Gln Asn Gly Val Lys Gln Ile Pro Phe 
65                  70                  75                  80  


Pro Ser Gly Thr Pro Leu His Ala Asn Ser Met Val Ser Glu Asn Val 
                85                  90                  95      


Ile Gln Ser Thr Ala Val Thr Thr Val Ser Ser Gly Thr Lys Glu Gln 
            100                 105                 110         


Ile Lys Gly Gly Thr Gly Asp Glu Lys Lys Ala Lys Glu Lys Ile Glu 
        115                 120                 125             


Lys Lys Gly Glu Lys Lys Glu Lys Lys Gln Gln Ser Ile Ala Gly Ser 
    130                 135                 140                 


Ala Asp Ser Lys Pro Ile Asp Val Ser Arg Leu Asp Leu Arg Ile Gly 
145                 150                 155                 160 


Cys Ile Ile Thr Ala Arg Lys His Pro Asp Ala Asp Ser Leu Tyr Val 
                165                 170                 175     


Glu Glu Val Asp Val Gly Glu Ile Ala Pro Arg Thr Val Val Ser Gly 
            180                 185                 190         


Leu Val Asn His Val Pro Leu Glu Gln Met Gln Asn Arg Met Val Ile 
        195                 200                 205             


Leu Leu Cys Asn Leu Lys Pro Ala Lys Met Arg Gly Val Leu Ser Gln 
    210                 215                 220                 


Ala Met Val Met Cys Ala Ser Ser Pro Glu Lys Ile Glu Ile Leu Ala 
225                 230                 235                 240 


Pro Pro Asn Gly Ser Val Pro Gly Asp Arg Ile Thr Phe Asp Ala Phe 
                245                 250                 255     


Pro Gly Glu Pro Asp Lys Glu Leu Asn Pro Lys Lys Lys Ile Trp Glu 
            260                 265                 270         


Gln Ile Gln Pro Asp Leu His Thr Asn Asp Glu Cys Val Ala Thr Tyr 
        275                 280                 285             


Lys Gly Val Pro Phe Glu Val Lys Gly Lys Gly Val Cys Arg Ala Gln 
    290                 295                 300                 


Thr Met Ser Asn Ser Gly Ile Lys 
305                 310         


<210>  1174
<211>  361
<212>  PRT
<213>  Human

<400>  1174

Met Ala Gln Pro Gly Asp Pro Arg Arg Leu Cys Arg Leu Val Gln Glu 
1               5                   10                  15      


Gly Arg Leu Arg Ala Leu Lys Glu Glu Leu Gln Ala Ala Gly Gly Cys 
            20                  25                  30          


Pro Gly Pro Ala Gly Asp Thr Leu Leu His Cys Ala Ala Arg His Gly 
        35                  40                  45              


His Arg Asp Val Leu Ala Tyr Leu Ala Glu Ala Trp Gly Met Asp Ile 
    50                  55                  60                  


Glu Ala Thr Asn Arg Asp Tyr Lys Arg Pro Leu His Glu Ala Ala Ser 
65                  70                  75                  80  


Met Gly His Arg Asp Cys Val Arg Tyr Leu Leu Gly Arg Gly Ala Ala 
                85                  90                  95      


Val Asp Cys Leu Lys Lys Ala Asp Trp Thr Pro Leu Met Met Ala Cys 
            100                 105                 110         


Thr Arg Lys Asn Leu Gly Val Ile Gln Glu Leu Val Glu His Gly Ala 
        115                 120                 125             


Asn Pro Leu Leu Lys Asn Lys Asp Gly Trp Asn Ser Phe His Ile Ala 
    130                 135                 140                 


Ser Arg Glu Gly Asp Pro Leu Ile Leu Gln Tyr Leu Leu Thr Val Cys 
145                 150                 155                 160 


Pro Gly Ala Trp Lys Thr Glu Ser Lys Ile Arg Arg Thr Pro Leu His 
                165                 170                 175     


Thr Ala Ala Met His Gly His Leu Glu Ala Val Lys Val Leu Leu Lys 
            180                 185                 190         


Arg Cys Gln Tyr Glu Pro Asp Tyr Arg Asp Asn Cys Gly Val Thr Ala 
        195                 200                 205             


Leu Met Asp Ala Ile Gln Cys Gly His Ile Asp Val Ala Arg Leu Leu 
    210                 215                 220                 


Leu Asp Glu His Gly Ala Cys Leu Ser Ala Glu Asp Ser Leu Gly Ala 
225                 230                 235                 240 


Gln Ala Leu His Arg Ala Ala Val Thr Gly Gln Asp Glu Ala Ile Arg 
                245                 250                 255     


Phe Leu Val Ser Glu Leu Gly Val Asp Val Asp Val Arg Ala Thr Ser 
            260                 265                 270         


Thr His Leu Thr Ala Leu His Tyr Ala Ala Lys Glu Gly His Thr Ser 
        275                 280                 285             


Thr Ile Gln Thr Leu Leu Ser Leu Gly Ala Asp Ile Asn Ser Lys Asp 
    290                 295                 300                 


Glu Lys Asn Arg Ser Ala Leu His Leu Ala Cys Ala Gly Gln His Leu 
305                 310                 315                 320 


Ala Cys Ala Lys Phe Leu Leu Gln Ser Gly Leu Lys Asp Ser Glu Asp 
                325                 330                 335     


Ile Thr Gly Thr Leu Ala Gln Gln Leu Pro Arg Arg Ala Asp Val Leu 
            340                 345                 350         


Gln Gly Ser Gly His Ser Ala Met Thr 
        355                 360     


<210>  1175
<211>  317
<212>  PRT
<213>  Human

<400>  1175

Met Lys Val Leu Trp Ala Ala Leu Leu Val Thr Phe Leu Ala Gly Cys 
1               5                   10                  15      


Gln Ala Lys Val Glu Gln Ala Val Glu Thr Glu Pro Glu Pro Glu Leu 
            20                  25                  30          


Arg Gln Gln Thr Glu Trp Gln Ser Gly Gln Arg Trp Glu Leu Ala Leu 
        35                  40                  45              


Gly Arg Phe Trp Asp Tyr Leu Arg Trp Val Gln Thr Leu Ser Glu Gln 
    50                  55                  60                  


Val Gln Glu Glu Leu Leu Ser Ser Gln Val Thr Gln Glu Leu Arg Ala 
65                  70                  75                  80  


Leu Met Asp Glu Thr Met Lys Glu Leu Lys Ala Tyr Lys Ser Glu Leu 
                85                  90                  95      


Glu Glu Gln Leu Thr Pro Val Ala Glu Glu Thr Arg Ala Arg Leu Ser 
            100                 105                 110         


Lys Glu Leu Gln Ala Ala Gln Ala Arg Leu Gly Ala Asp Met Glu Asp 
        115                 120                 125             


Val Cys Gly Arg Leu Val Gln Tyr Arg Gly Glu Val Gln Ala Met Leu 
    130                 135                 140                 


Gly Gln Ser Thr Glu Glu Leu Arg Val Arg Leu Ala Ser His Leu Arg 
145                 150                 155                 160 


Lys Leu Arg Lys Arg Leu Leu Arg Asp Ala Asp Asp Leu Gln Lys Arg 
                165                 170                 175     


Leu Ala Val Tyr Gln Ala Gly Ala Arg Glu Gly Ala Glu Arg Gly Leu 
            180                 185                 190         


Ser Ala Ile Arg Glu Arg Leu Gly Pro Leu Val Glu Gln Gly Arg Val 
        195                 200                 205             


Arg Ala Ala Thr Val Gly Ser Leu Ala Gly Gln Pro Leu Gln Glu Arg 
    210                 215                 220                 


Ala Gln Ala Trp Gly Glu Arg Leu Arg Ala Arg Met Glu Glu Met Gly 
225                 230                 235                 240 


Ser Arg Thr Arg Asp Arg Leu Asp Glu Val Lys Glu Gln Val Ala Glu 
                245                 250                 255     


Val Arg Ala Lys Leu Glu Glu Gln Ala Gln Gln Ile Arg Leu Gln Ala 
            260                 265                 270         


Glu Ala Phe Gln Ala Arg Leu Lys Ser Trp Phe Glu Pro Leu Val Glu 
        275                 280                 285             


Asp Met Gln Arg Gln Trp Ala Gly Leu Val Glu Lys Val Gln Ala Ala 
    290                 295                 300                 


Val Gly Thr Ser Ala Ala Pro Val Pro Ser Asp Asn His 
305                 310                 315         


<210>  1176
<211>  731
<212>  PRT
<213>  Human

<400>  1176

Met Leu Ser Ser Arg Trp Trp Pro Ser Ser Trp Gly Ile Leu Gly Leu 
1               5                   10                  15      


Gly Pro Arg Ser Pro Pro Arg Gly Ser Gln Leu Cys Ala Leu Tyr Ala 
            20                  25                  30          


Phe Thr Tyr Thr Gly Ala Asp Gly Gln Gln Val Ser Leu Ala Glu Gly 
        35                  40                  45              


Asp Arg Phe Leu Leu Leu Arg Lys Thr Asn Ser Asp Trp Trp Leu Ala 
    50                  55                  60                  


Arg Arg Leu Glu Ala Pro Ser Thr Ser Arg Pro Ile Phe Val Pro Ala 
65                  70                  75                  80  


Ala Tyr Met Ile Glu Glu Ser Ile Pro Ser Gln Ser Pro Thr Thr Val 
                85                  90                  95      


Ile Pro Gly Gln Leu Leu Trp Thr Pro Gly Pro Lys Leu Phe His Gly 
            100                 105                 110         


Ser Leu Glu Glu Leu Ser Gln Ala Leu Pro Ser Arg Ala Gln Ala Ser 
        115                 120                 125             


Ser Glu Gln Pro Pro Pro Leu Pro Arg Lys Met Cys Arg Ser Val Ser 
    130                 135                 140                 


Thr Asp Asn Leu Ser Pro Ser Leu Leu Lys Pro Phe Gln Glu Gly Pro 
145                 150                 155                 160 


Ser Gly Arg Ser Leu Ser Gln Glu Asp Leu Pro Ser Glu Ala Ser Ala 
                165                 170                 175     


Ser Thr Ala Gly Pro Gln Pro Leu Met Ser Glu Pro Pro Val Tyr Cys 
            180                 185                 190         


Asn Leu Val Asp Leu Arg Arg Cys Pro Arg Ser Pro Pro Pro Gly Pro 
        195                 200                 205             


Ala Cys Pro Leu Leu Gln Arg Leu Asp Ala Trp Glu Gln His Leu Asp 
    210                 215                 220                 


Pro Asn Ser Gly Arg Cys Phe Tyr Ile Asn Ser Leu Thr Gly Cys Lys 
225                 230                 235                 240 


Ser Trp Lys Pro Pro Arg Arg Ser Arg Ser Glu Thr Asn Pro Gly Ser 
                245                 250                 255     


Met Glu Gly Thr Gln Thr Leu Lys Arg Asn Asn Asp Val Leu Gln Pro 
            260                 265                 270         


Gln Ala Lys Gly Phe Arg Ser Asp Thr Gly Thr Pro Glu Pro Leu Asp 
        275                 280                 285             


Pro Gln Gly Ser Leu Ser Leu Ser Gln Arg Thr Ser Gln Leu Asp Pro 
    290                 295                 300                 


Pro Ala Leu Gln Ala Pro Arg Pro Leu Pro Gln Leu Leu Asp Asp Pro 
305                 310                 315                 320 


His Glu Val Glu Lys Ser Gly Leu Leu Asn Met Thr Lys Ile Ala Gln 
                325                 330                 335     


Gly Gly Arg Lys Leu Arg Lys Asn Trp Gly Pro Ser Trp Val Val Leu 
            340                 345                 350         


Thr Gly Asn Ser Leu Val Phe Tyr Arg Glu Pro Pro Pro Thr Ala Pro 
        355                 360                 365             


Ser Ser Gly Trp Gly Pro Ala Gly Ser Arg Pro Glu Ser Ser Val Asp 
    370                 375                 380                 


Leu Arg Gly Ala Ala Leu Ala His Gly Arg His Leu Ser Ser Arg Arg 
385                 390                 395                 400 


Asn Val Leu His Ile Arg Thr Ile Pro Gly His Glu Phe Leu Leu Gln 
                405                 410                 415     


Ser Asp His Glu Thr Glu Leu Arg Ala Trp His Arg Ala Leu Arg Thr 
            420                 425                 430         


Val Ile Glu Arg Leu Asp Arg Glu Asn Pro Leu Glu Leu Arg Leu Ser 
        435                 440                 445             


Gly Ser Gly Pro Ala Glu Leu Ser Ala Gly Glu Asp Glu Glu Glu Glu 
    450                 455                 460                 


Ser Glu Leu Val Ser Lys Pro Leu Leu Arg Leu Ser Ser Arg Arg Ser 
465                 470                 475                 480 


Ser Ile Arg Gly Pro Glu Gly Thr Glu Gln Asn Arg Val Arg Asn Lys 
                485                 490                 495     


Leu Lys Arg Leu Ile Ala Lys Arg Pro Pro Leu Gln Ser Leu Gln Glu 
            500                 505                 510         


Arg Gly Leu Leu Arg Asp Gln Val Phe Gly Cys Gln Leu Glu Ser Leu 
        515                 520                 525             


Cys Gln Arg Glu Gly Asp Thr Val Pro Ser Phe Leu Arg Leu Cys Ile 
    530                 535                 540                 


Ala Ala Val Asp Lys Arg Gly Leu Asp Val Asp Gly Ile Tyr Arg Val 
545                 550                 555                 560 


Ser Gly Asn Leu Ala Val Val Gln Lys Leu Arg Phe Leu Val Asp Arg 
                565                 570                 575     


Glu Arg Ala Val Thr Ser Asp Gly Arg Tyr Val Phe Pro Glu Gln Pro 
            580                 585                 590         


Gly Gln Glu Gly Arg Leu Asp Leu Asp Ser Thr Glu Trp Asp Asp Ile 
        595                 600                 605             


His Val Val Thr Gly Ala Leu Lys Leu Phe Leu Arg Glu Leu Pro Gln 
    610                 615                 620                 


Pro Leu Val Pro Pro Leu Leu Leu Pro His Phe Arg Ala Ala Leu Ala 
625                 630                 635                 640 


Leu Ser Glu Ser Glu Gln Cys Leu Ser Gln Ile Gln Glu Leu Ile Gly 
                645                 650                 655     


Ser Met Pro Lys Pro Asn His Asp Thr Leu Arg Tyr Leu Leu Glu His 
            660                 665                 670         


Leu Cys Arg Val Ile Ala His Ser Asp Lys Asn Arg Met Thr Pro His 
        675                 680                 685             


Asn Leu Gly Ile Val Phe Gly Pro Thr Leu Phe Arg Pro Glu Gln Glu 
    690                 695                 700                 


Thr Ser Asp Pro Ala Ala His Ala Leu Tyr Pro Gly Gln Leu Val Gln 
705                 710                 715                 720 


Leu Met Leu Thr Asn Phe Thr Ser Leu Phe Pro 
                725                 730     


<210>  1177
<211>  1044
<212>  PRT
<213>  Human

<400>  1177

Met Lys Gly Thr Arg Ala Ile Gly Ser Val Pro Glu Arg Ser Pro Ala 
1               5                   10                  15      


Gly Val Asp Leu Ser Leu Thr Gly Leu Pro Pro Pro Val Ser Arg Arg 
            20                  25                  30          


Pro Gly Ser Ala Ala Thr Thr Lys Pro Ile Val Arg Ser Val Ser Val 
        35                  40                  45              


Val Thr Gly Ser Glu Gln Lys Arg Lys Val Leu Glu Ala Thr Gly Pro 
    50                  55                  60                  


Gly Gly Ser Gln Ala Ile Asn Asn Leu Arg Arg Ser Asn Ser Thr Thr 
65                  70                  75                  80  


Gln Val Ser Gln Pro Arg Ser Gly Ser Pro Arg Pro Thr Glu Pro Thr 
                85                  90                  95      


Asp Phe Leu Met Leu Phe Glu Gly Ser Pro Ser Gly Lys Lys Arg Pro 
            100                 105                 110         


Ala Ser Leu Ser Thr Ala Pro Ser Glu Lys Gly Ala Thr Trp Asn Val 
        115                 120                 125             


Leu Asp Asp Gln Pro Arg Gly Phe Thr Leu Pro Ser Asn Ala Arg Ser 
    130                 135                 140                 


Ser Ser Ala Leu Asp Ser Pro Ala Gly Pro Arg Arg Lys Glu Cys Thr 
145                 150                 155                 160 


Val Ala Leu Ala Pro Asn Phe Thr Ala Asn Asn Arg Ser Asn Lys Gly 
                165                 170                 175     


Ala Val Gly Asn Cys Val Thr Thr Met Val His Asn Arg Tyr Thr Pro 
            180                 185                 190         


Ser Glu Arg Ala Pro Pro Leu Lys Ser Ser Asn Gln Thr Ala Pro Ser 
        195                 200                 205             


Leu Asn Asn Ile Ile Lys Ala Ala Thr Cys Glu Gly Ser Glu Ser Ser 
    210                 215                 220                 


Gly Phe Gly Lys Leu Pro Lys Asn Val Ser Ser Ala Thr His Ser Ala 
225                 230                 235                 240 


Arg Asn Asn Thr Gly Gly Ser Thr Gly Leu Pro Arg Arg Lys Glu Val 
                245                 250                 255     


Thr Glu Glu Glu Ala Glu Arg Phe Ile His Gln Val Asn Gln Ala Thr 
            260                 265                 270         


Val Thr Ile Gln Arg Trp Tyr Arg His Gln Val Gln Arg Arg Gly Ala 
        275                 280                 285             


Gly Ala Ala Arg Leu Glu His Leu Leu Gln Ala Lys Arg Glu Glu Gln 
    290                 295                 300                 


Arg Gln Arg Ser Gly Glu Gly Thr Leu Leu Asp Leu His Gln Gln Lys 
305                 310                 315                 320 


Glu Ala Ala Arg Arg Lys Ala Arg Glu Glu Lys Ala Arg Gln Ala Arg 
                325                 330                 335     


Arg Ala Ala Ile Gln Glu Leu Gln Gln Lys Arg Ala Leu Arg Ala Gln 
            340                 345                 350         


Lys Ala Ser Thr Ala Glu Arg Gly Pro Pro Glu Asn Pro Arg Glu Thr 
        355                 360                 365             


Arg Val Pro Gly Met Arg Gln Pro Ala Gln Glu Leu Ser Pro Thr Pro 
    370                 375                 380                 


Gly Gly Thr Ala His Gln Ala Leu Lys Ala Asn Asn Thr Gly Gly Gly 
385                 390                 395                 400 


Leu Pro Ala Ala Gly Pro Gly Asp Arg Cys Leu Pro Thr Ser Asp Ser 
                405                 410                 415     


Ser Pro Glu Pro Gln Gln Pro Pro Glu Asp Arg Thr Gln Asp Val Leu 
            420                 425                 430         


Ala Gln Asp Ala Ala Gly Asp Asn Leu Glu Met Met Ala Pro Ser Arg 
        435                 440                 445             


Gly Ser Ala Lys Ser Arg Gly Pro Leu Glu Glu Leu Leu His Thr Leu 
    450                 455                 460                 


Gln Leu Leu Glu Lys Glu Pro Asp Val Leu Pro Arg Pro Arg Thr His 
465                 470                 475                 480 


His Arg Gly Arg Tyr Ala Trp Ala Ser Glu Glu Asp Asp Ala Ser Ser 
                485                 490                 495     


Leu Thr Ala Asp Asn Leu Glu Lys Phe Gly Lys Leu Ser Ala Phe Pro 
            500                 505                 510         


Glu Pro Pro Glu Asp Gly Thr Leu Leu Ser Glu Ala Lys Leu Gln Ser 
        515                 520                 525             


Ile Met Ser Phe Leu Asp Glu Met Glu Lys Ser Gly Gln Asp Gln Leu 
    530                 535                 540                 


Asp Ser Gln Gln Glu Gly Trp Val Pro Glu Ala Gly Pro Gly Pro Leu 
545                 550                 555                 560 


Glu Leu Gly Ser Glu Val Ser Thr Ser Val Met Arg Leu Lys Leu Glu 
                565                 570                 575     


Val Glu Glu Lys Lys Gln Ala Met Leu Leu Leu Gln Arg Ala Leu Ala 
            580                 585                 590         


Gln Gln Arg Asp Leu Thr Ala Arg Arg Val Lys Glu Thr Glu Lys Ala 
        595                 600                 605             


Leu Ser Arg Gln Leu Gln Arg Gln Arg Glu His Tyr Glu Ala Thr Ile 
    610                 615                 620                 


Gln Arg His Leu Ala Phe Ile Asp Gln Leu Ile Glu Asp Lys Lys Val 
625                 630                 635                 640 


Leu Ser Glu Lys Cys Glu Ala Val Val Ala Glu Leu Lys Gln Glu Asp 
                645                 650                 655     


Gln Arg Cys Thr Glu Arg Val Ala Gln Ala Gln Ala Gln His Glu Leu 
            660                 665                 670         


Glu Ile Lys Lys Leu Lys Glu Leu Met Ser Ala Thr Glu Lys Ala Arg 
        675                 680                 685             


Arg Glu Lys Trp Ile Ser Glu Lys Thr Lys Lys Ile Lys Glu Val Thr 
    690                 695                 700                 


Val Arg Gly Leu Glu Pro Glu Ile Gln Lys Leu Ile Ala Arg His Lys 
705                 710                 715                 720 


Gln Glu Val Arg Arg Leu Lys Ser Leu His Glu Ala Glu Leu Leu Gln 
                725                 730                 735     


Ser Asp Glu Arg Ala Ser Gln Arg Cys Leu Arg Gln Ala Glu Glu Leu 
            740                 745                 750         


Arg Glu Gln Leu Glu Arg Glu Lys Glu Ala Leu Gly Gln Gln Glu Arg 
        755                 760                 765             


Glu Arg Ala Arg Gln Arg Gln Arg Ala Glu Leu Glu Glu Leu Arg Gln 
    770                 775                 780                 


Gln Leu Glu Glu Ser Ser Ser Ala Leu Thr Arg Ala Leu Arg Ala Glu 
785                 790                 795                 800 


Phe Glu Lys Gly Arg Glu Glu Gln Glu Arg Arg His Gln Met Glu Leu 
                805                 810                 815     


Asn Thr Leu Lys Gln Gln Leu Glu Leu Glu Arg Gln Ala Trp Glu Ala 
            820                 825                 830         


Gly Arg Thr Arg Lys Glu Glu Ala Trp Leu Leu Asn Arg Glu Gln Glu 
        835                 840                 845             


Leu Arg Glu Glu Ile Arg Lys Gly Arg Asp Lys Glu Ile Glu Leu Val 
    850                 855                 860                 


Ile His Arg Leu Glu Ala Asp Met Ala Leu Ala Lys Glu Glu Ser Glu 
865                 870                 875                 880 


Lys Ala Ala Glu Ser Arg Ile Lys Arg Leu Arg Asp Lys Tyr Glu Ala 
                885                 890                 895     


Glu Leu Ser Glu Leu Glu Gln Ser Glu Arg Lys Leu Gln Glu Arg Cys 
            900                 905                 910         


Ser Glu Leu Lys Gly Gln Leu Gly Glu Ala Glu Gly Glu Asn Leu Arg 
        915                 920                 925             


Leu Gln Gly Leu Val Arg Gln Lys Glu Arg Ala Leu Glu Asp Ala Gln 
    930                 935                 940                 


Ala Val Asn Glu Gln Leu Ser Ser Glu Arg Ser Asn Leu Ala Gln Val 
945                 950                 955                 960 


Ile Arg Gln Glu Phe Glu Asp Arg Leu Ala Ala Ser Glu Glu Glu Thr 
                965                 970                 975     


Arg Gln Ala Lys Ala Glu Leu Ala Thr Leu Gln Ala Arg Gln Gln Leu 
            980                 985                 990         


Glu Leu Glu Glu Val His Arg Arg  Val Lys Thr Ala Leu  Ala Arg Lys 
        995                 1000                 1005             


Glu Glu  Ala Val Ser Ser Leu  Arg Thr Gln His Glu  Ala Ala Val 
    1010                 1015                 1020             


Lys Arg  Ala Asp His Leu Glu  Glu Leu Leu Glu Gln  His Arg Arg 
    1025                 1030                 1035             


Pro Thr  Pro Ser Thr Lys 
    1040                 


<210>  1178
<211>  511
<212>  PRT
<213>  Human

<400>  1178

Met Ser Arg Gly Pro Glu Glu Val Asn Arg Leu Thr Glu Ser Thr Tyr 
1               5                   10                  15      


Arg Asn Val Met Glu Gln Phe Asn Pro Gly Leu Arg Asn Leu Ile Asn 
            20                  25                  30          


Leu Gly Lys Asn Tyr Glu Lys Ala Val Asn Ala Met Ile Leu Ala Gly 
        35                  40                  45              


Lys Ala Tyr Tyr Asp Gly Val Ala Lys Ile Gly Glu Ile Ala Thr Gly 
    50                  55                  60                  


Ser Pro Val Ser Thr Glu Leu Gly His Val Leu Ile Glu Ile Ser Ser 
65                  70                  75                  80  


Thr His Lys Lys Leu Asn Glu Ser Leu Asp Glu Asn Phe Lys Lys Phe 
                85                  90                  95      


His Lys Glu Ile Ile His Glu Leu Glu Lys Lys Ile Glu Leu Asp Val 
            100                 105                 110         


Lys Tyr Met Asn Ala Thr Leu Lys Arg Tyr Gln Thr Glu His Lys Asn 
        115                 120                 125             


Lys Leu Glu Ser Leu Glu Lys Ser Gln Ala Glu Leu Lys Lys Ile Arg 
    130                 135                 140                 


Arg Lys Ser Gln Gly Ser Arg Asn Ala Leu Lys Tyr Glu His Lys Glu 
145                 150                 155                 160 


Ile Glu Tyr Val Glu Thr Val Thr Ser Arg Gln Ser Glu Ile Gln Lys 
                165                 170                 175     


Phe Ile Ala Asp Gly Cys Lys Glu Ala Leu Leu Glu Glu Lys Arg Arg 
            180                 185                 190         


Phe Cys Phe Leu Val Asp Lys His Cys Gly Phe Ala Asn His Ile His 
        195                 200                 205             


Tyr Tyr His Leu Gln Ser Ala Glu Leu Leu Asn Ser Lys Leu Pro Arg 
    210                 215                 220                 


Trp Gln Glu Thr Cys Val Asp Ala Ile Lys Val Pro Glu Lys Ile Met 
225                 230                 235                 240 


Asn Met Ile Glu Glu Ile Lys Thr Pro Ala Ser Thr Pro Val Ser Gly 
                245                 250                 255     


Thr Pro Gln Ala Ser Pro Met Ile Glu Arg Ser Asn Val Val Arg Lys 
            260                 265                 270         


Asp Tyr Asp Thr Leu Ser Lys Cys Ser Pro Lys Met Pro Pro Ala Pro 
        275                 280                 285             


Ser Gly Arg Ala Tyr Thr Ser Pro Leu Ile Asp Met Phe Asn Asn Pro 
    290                 295                 300                 


Ala Thr Ala Ala Pro Asn Ser Gln Arg Val Asn Asn Ser Thr Gly Thr 
305                 310                 315                 320 


Ser Glu Asp Pro Ser Leu Gln Arg Ser Val Ser Val Ala Thr Gly Leu 
                325                 330                 335     


Asn Met Met Lys Lys Gln Lys Val Lys Thr Ile Phe Pro His Thr Ala 
            340                 345                 350         


Gly Ser Asn Lys Thr Leu Leu Ser Phe Ala Gln Gly Asp Val Ile Thr 
        355                 360                 365             


Leu Leu Ile Pro Glu Glu Lys Asp Gly Trp Leu Tyr Gly Glu His Asp 
    370                 375                 380                 


Val Ser Lys Ala Arg Gly Trp Phe Pro Ser Ser Tyr Thr Lys Leu Leu 
385                 390                 395                 400 


Glu Glu Asn Glu Thr Glu Ala Val Thr Val Pro Thr Pro Ser Pro Thr 
                405                 410                 415     


Pro Val Arg Ser Ile Ser Thr Val Asn Leu Ser Glu Asn Ser Ser Val 
            420                 425                 430         


Val Ile Pro Pro Pro Asp Tyr Leu Glu Cys Leu Ser Met Gly Ala Ala 
        435                 440                 445             


Ala Asp Arg Arg Ala Asp Ser Ala Arg Thr Thr Ser Thr Phe Lys Ala 
    450                 455                 460                 


Pro Ala Ser Lys Pro Glu Thr Ala Ala Pro Asn Asp Ala Asn Gly Thr 
465                 470                 475                 480 


Ala Lys Pro Pro Phe Leu Ser Gly Glu Asn Pro Phe Ala Thr Val Lys 
                485                 490                 495     


Leu Arg Pro Thr Val Thr Asn Asp Arg Ser Ala Pro Ile Ile Arg 
            500                 505                 510     


<210>  1179
<211>  428
<212>  PRT
<213>  Human

<400>  1179

Met Ala Glu Asn Asp Val Asp Asn Glu Leu Leu Asp Tyr Glu Asp Asp 
1               5                   10                  15      


Glu Val Glu Thr Ala Ala Gly Gly Asp Gly Ala Glu Ala Pro Ala Lys 
            20                  25                  30          


Lys Asp Val Lys Gly Ser Tyr Val Ser Ile His Ser Ser Gly Phe Arg 
        35                  40                  45              


Asp Phe Leu Leu Lys Pro Glu Leu Leu Arg Ala Ile Val Asp Cys Gly 
    50                  55                  60                  


Phe Glu His Pro Ser Glu Val Gln His Glu Cys Ile Pro Gln Ala Ile 
65                  70                  75                  80  


Leu Gly Met Asp Val Leu Cys Gln Ala Lys Ser Gly Met Gly Lys Thr 
                85                  90                  95      


Ala Val Phe Val Leu Ala Thr Leu Gln Gln Leu Glu Pro Val Thr Gly 
            100                 105                 110         


Gln Val Ser Val Leu Val Met Cys His Thr Arg Glu Leu Ala Phe Gln 
        115                 120                 125             


Ile Ser Lys Glu Tyr Glu Arg Phe Ser Lys Tyr Met Pro Asn Val Lys 
    130                 135                 140                 


Val Ala Val Phe Phe Gly Gly Leu Ser Ile Lys Lys Asp Glu Glu Val 
145                 150                 155                 160 


Leu Lys Lys Asn Cys Pro His Ile Val Val Gly Thr Pro Gly Arg Ile 
                165                 170                 175     


Leu Ala Leu Ala Arg Asn Lys Ser Leu Asn Leu Lys His Ile Lys His 
            180                 185                 190         


Phe Ile Leu Asp Glu Cys Asp Lys Met Leu Glu Gln Leu Asp Met Arg 
        195                 200                 205             


Arg Asp Val Gln Glu Ile Phe Arg Met Thr Pro His Glu Lys Gln Val 
    210                 215                 220                 


Met Met Phe Ser Ala Thr Leu Ser Lys Glu Ile Arg Pro Val Cys Arg 
225                 230                 235                 240 


Lys Phe Met Gln Asp Pro Met Glu Ile Phe Val Asp Asp Glu Thr Lys 
                245                 250                 255     


Leu Thr Leu His Gly Leu Gln Gln Tyr Tyr Val Lys Leu Lys Asp Asn 
            260                 265                 270         


Glu Lys Asn Arg Lys Leu Phe Asp Leu Leu Asp Val Leu Glu Phe Asn 
        275                 280                 285             


Gln Val Val Ile Phe Val Lys Ser Val Gln Arg Cys Ile Ala Leu Ala 
    290                 295                 300                 


Gln Leu Leu Val Glu Gln Asn Phe Pro Ala Ile Ala Ile His Arg Gly 
305                 310                 315                 320 


Met Pro Gln Glu Glu Arg Leu Ser Arg Tyr Gln Gln Phe Lys Asp Phe 
                325                 330                 335     


Gln Arg Arg Ile Leu Val Ala Thr Asn Leu Phe Gly Arg Gly Met Asp 
            340                 345                 350         


Ile Glu Arg Val Asn Ile Ala Phe Asn Tyr Asp Met Pro Glu Asp Ser 
        355                 360                 365             


Asp Thr Tyr Leu His Arg Val Ala Arg Ala Gly Arg Phe Gly Thr Lys 
    370                 375                 380                 


Gly Leu Ala Ile Thr Phe Val Ser Asp Glu Asn Asp Ala Lys Ile Leu 
385                 390                 395                 400 


Asn Asp Val Gln Asp Arg Phe Glu Val Asn Ile Ser Glu Leu Pro Asp 
                405                 410                 415     


Glu Ile Asp Ile Ser Ser Tyr Ile Glu Gln Thr Arg 
            420                 425             


<210>  1180
<211>  801
<212>  PRT
<213>  Human

<400>  1180

Met Leu Gln Asn Val Thr Pro His Asn Lys Leu Pro Gly Glu Gly Asn 
1               5                   10                  15      


Ala Gly Leu Leu Gly Leu Gly Pro Glu Ala Ala Ala Pro Gly Lys Arg 
            20                  25                  30          


Ile Arg Lys Pro Ser Leu Leu Tyr Glu Gly Phe Glu Ser Pro Thr Met 
        35                  40                  45              


Ala Ser Val Pro Ala Leu Gln Leu Thr Pro Ala Asn Pro Pro Pro Pro 
    50                  55                  60                  


Glu Val Ser Asn Pro Lys Lys Pro Gly Arg Val Thr Asn Gln Leu Gln 
65                  70                  75                  80  


Tyr Leu His Lys Val Val Met Lys Ala Leu Trp Lys His Gln Phe Ala 
                85                  90                  95      


Trp Pro Phe Arg Gln Pro Val Asp Ala Val Lys Leu Gly Leu Pro Asp 
            100                 105                 110         


Tyr His Lys Ile Ile Lys Gln Pro Met Asp Met Gly Thr Ile Lys Arg 
        115                 120                 125             


Arg Leu Glu Asn Asn Tyr Tyr Trp Ala Ala Ser Glu Cys Met Gln Asp 
    130                 135                 140                 


Phe Asn Thr Met Phe Thr Asn Cys Tyr Ile Tyr Asn Lys Pro Thr Asp 
145                 150                 155                 160 


Asp Ile Val Leu Met Ala Gln Thr Leu Glu Lys Ile Phe Leu Gln Lys 
                165                 170                 175     


Val Ala Ser Met Pro Gln Glu Glu Gln Glu Leu Val Val Thr Ile Pro 
            180                 185                 190         


Lys Asn Ser His Lys Lys Gly Ala Lys Leu Ala Ala Leu Gln Gly Ser 
        195                 200                 205             


Val Thr Ser Ala His Gln Val Pro Ala Val Ser Ser Val Ser His Thr 
    210                 215                 220                 


Ala Leu Tyr Thr Pro Pro Pro Glu Ile Pro Thr Thr Val Leu Asn Ile 
225                 230                 235                 240 


Pro His Pro Ser Val Ile Ser Ser Pro Leu Leu Lys Ser Leu His Ser 
                245                 250                 255     


Ala Gly Pro Pro Leu Leu Ala Val Thr Ala Ala Pro Pro Ala Gln Pro 
            260                 265                 270         


Leu Ala Lys Lys Lys Gly Val Lys Arg Lys Ala Asp Thr Thr Thr Pro 
        275                 280                 285             


Thr Pro Thr Ala Ile Leu Ala Pro Gly Ser Pro Ala Ser Pro Pro Gly 
    290                 295                 300                 


Ser Leu Glu Pro Lys Ala Ala Arg Leu Pro Pro Met Arg Arg Glu Ser 
305                 310                 315                 320 


Gly Arg Pro Ile Lys Pro Pro Arg Lys Asp Leu Pro Asp Ser Gln Gln 
                325                 330                 335     


Gln His Gln Ser Ser Lys Lys Gly Lys Leu Ser Glu Gln Leu Lys His 
            340                 345                 350         


Cys Asn Gly Ile Leu Lys Glu Leu Leu Ser Lys Lys His Ala Ala Tyr 
        355                 360                 365             


Ala Trp Pro Phe Tyr Lys Pro Val Asp Ala Ser Ala Leu Gly Leu His 
    370                 375                 380                 


Asp Tyr His Asp Ile Ile Lys His Pro Met Asp Leu Ser Thr Val Lys 
385                 390                 395                 400 


Arg Lys Met Glu Asn Arg Asp Tyr Arg Asp Ala Gln Glu Phe Ala Ala 
                405                 410                 415     


Asp Val Arg Leu Met Phe Ser Asn Cys Tyr Lys Tyr Asn Pro Pro Asp 
            420                 425                 430         


His Asp Val Val Ala Met Ala Arg Lys Leu Gln Asp Val Phe Glu Phe 
        435                 440                 445             


Arg Tyr Ala Lys Met Pro Asp Glu Pro Leu Glu Pro Gly Pro Leu Pro 
    450                 455                 460                 


Val Ser Thr Ala Met Pro Pro Gly Leu Ala Lys Ser Ser Ser Glu Ser 
465                 470                 475                 480 


Ser Ser Glu Glu Ser Ser Ser Glu Ser Ser Ser Glu Glu Glu Glu Glu 
                485                 490                 495     


Glu Asp Glu Glu Asp Glu Glu Glu Glu Glu Ser Glu Ser Ser Asp Ser 
            500                 505                 510         


Glu Glu Glu Arg Ala His Arg Leu Ala Glu Leu Gln Glu Gln Leu Arg 
        515                 520                 525             


Ala Val His Glu Gln Leu Ala Ala Leu Ser Gln Gly Pro Ile Ser Lys 
    530                 535                 540                 


Pro Lys Arg Lys Arg Glu Lys Lys Glu Lys Lys Lys Lys Arg Lys Ala 
545                 550                 555                 560 


Glu Lys His Arg Gly Arg Ala Gly Ala Asp Glu Asp Asp Lys Gly Pro 
                565                 570                 575     


Arg Ala Pro Arg Pro Pro Gln Pro Lys Lys Ser Lys Lys Ala Ser Gly 
            580                 585                 590         


Ser Gly Gly Gly Ser Ala Ala Leu Gly Pro Ser Gly Phe Gly Pro Ser 
        595                 600                 605             


Gly Gly Ser Gly Thr Lys Leu Pro Lys Lys Ala Thr Lys Thr Ala Pro 
    610                 615                 620                 


Pro Ala Leu Pro Thr Gly Tyr Asp Ser Glu Glu Glu Glu Glu Ser Arg 
625                 630                 635                 640 


Pro Met Ser Tyr Asp Glu Lys Arg Gln Leu Ser Leu Asp Ile Asn Lys 
                645                 650                 655     


Leu Pro Gly Glu Lys Leu Gly Arg Val Val His Ile Ile Gln Ala Arg 
            660                 665                 670         


Glu Pro Ser Leu Arg Asp Ser Asn Pro Glu Glu Ile Glu Ile Asp Phe 
        675                 680                 685             


Glu Thr Leu Lys Pro Ser Thr Leu Arg Glu Leu Glu Arg Tyr Val Leu 
    690                 695                 700                 


Ser Cys Leu Arg Lys Lys Pro Arg Lys Pro Tyr Thr Ile Lys Lys Pro 
705                 710                 715                 720 


Val Gly Lys Thr Lys Glu Glu Leu Ala Leu Glu Lys Lys Arg Glu Leu 
                725                 730                 735     


Glu Lys Arg Leu Gln Asp Val Ser Gly Gln Leu Asn Ser Thr Lys Lys 
            740                 745                 750         


Pro Pro Lys Lys Ala Asn Glu Lys Thr Glu Ser Ser Ser Ala Gln Gln 
        755                 760                 765             


Val Ala Val Ser Arg Leu Ser Ala Ser Ser Ser Ser Ser Asp Ser Ser 
    770                 775                 780                 


Ser Ser Ser Ser Ser Ser Ser Ser Ser Asp Thr Ser Asp Ser Asp Ser 
785                 790                 795                 800 


Gly 
    


<210>  1181
<211>  304
<212>  PRT
<213>  Human

<400>  1181

Met Ala Asp Asn Ser Ser Asp Glu Cys Glu Glu Glu Asn Asn Lys Glu 
1               5                   10                  15      


Lys Lys Lys Thr Ser Gln Leu Thr Pro Gln Arg Gly Phe Ser Glu Asn 
            20                  25                  30          


Glu Asp Asp Asp Gly Asp Asp Asp Asp Ser Ser Glu Thr Asp Ser Asp 
        35                  40                  45              


Ser Asp Asp Asp Asp Glu Glu His Gly Ala Pro Leu Glu Gly Ala Tyr 
    50                  55                  60                  


Asp Pro Ala Asp Tyr Glu His Leu Pro Val Ser Ala Glu Ile Lys Glu 
65                  70                  75                  80  


Leu Phe Gln Tyr Ile Ser Arg Tyr Thr Pro Gln Leu Ile Asp Leu Asp 
                85                  90                  95      


His Lys Leu Lys Pro Phe Ile Pro Asp Phe Ile Pro Ala Val Gly Asp 
            100                 105                 110         


Ile Asp Ala Phe Leu Lys Val Pro Arg Pro Asp Gly Lys Pro Asp Asn 
        115                 120                 125             


Leu Gly Leu Leu Val Leu Asp Glu Pro Ser Thr Lys Gln Ser Asp Pro 
    130                 135                 140                 


Thr Val Leu Ser Leu Trp Leu Thr Glu Asn Ser Lys Gln His Asn Ile 
145                 150                 155                 160 


Thr Gln His Met Lys Val Lys Ser Leu Glu Asp Ala Glu Lys Asn Pro 
                165                 170                 175     


Lys Ala Ile Asp Thr Trp Ile Glu Ser Ile Ser Glu Leu His Arg Ser 
            180                 185                 190         


Lys Pro Pro Ala Thr Val His Tyr Thr Arg Pro Met Pro Asp Ile Asp 
        195                 200                 205             


Thr Leu Met Gln Glu Trp Ser Pro Glu Phe Glu Glu Leu Leu Gly Lys 
    210                 215                 220                 


Val Ser Leu Pro Thr Ala Glu Ile Asp Cys Ser Leu Ala Glu Tyr Ile 
225                 230                 235                 240 


Asp Met Ile Cys Ala Ile Leu Asp Ile Pro Val Tyr Lys Ser Arg Ile 
                245                 250                 255     


Gln Ser Leu His Leu Leu Phe Ser Leu Tyr Ser Glu Phe Lys Asn Ser 
            260                 265                 270         


Gln His Phe Lys Ala Leu Ala Glu Gly Lys Lys Ala Phe Thr Pro Ser 
        275                 280                 285             


Ser Asn Ser Thr Ser Gln Ala Gly Asp Met Glu Thr Leu Thr Phe Ser 
    290                 295                 300                 


<210>  1182
<211>  223
<212>  PRT
<213>  Human

<400>  1182

Met Trp Lys Pro Ser Pro Ser Ser Ser Pro Ala Ser Trp Ser Cys Thr 
1               5                   10                  15      


Ala Leu Arg Ala Pro Gln Ser Cys Leu Arg Ala Ala Thr Val Arg Pro 
            20                  25                  30          


Val Thr Leu Gln Ala Arg Ala Asp Ser Pro Thr Val Pro Glu Pro Val 
        35                  40                  45              


His Arg Pro Gln Asp Pro Trp His Ile Pro Gly Val Pro Glu Pro Val 
    50                  55                  60                  


His Arg Pro Gln Asp Pro Trp His Ile Pro Gly Val Pro Glu Pro Val 
65                  70                  75                  80  


His Arg Pro Gln Asp Pro Trp His Ile Pro Gly Val Pro Glu Pro Val 
                85                  90                  95      


His Arg Pro Gln Asp Pro Trp His Ile Pro Gly Val Pro Glu Pro Val 
            100                 105                 110         


His Arg Pro Gln Asp Pro Trp Pro Trp Leu Gln Leu Val Pro Pro Ala 
        115                 120                 125             


Glu Leu Ala Tyr Cys Leu Leu Met Leu Leu Leu Ala His Cys Met Lys 
    130                 135                 140                 


Gln Gln Ala Arg Pro Gly His Pro Asp Phe Leu His Arg Glu Ala Trp 
145                 150                 155                 160 


Ala Cys Leu Ser Ala Ala Gly Gly Leu Ala Ser Pro Gly Leu Leu Leu 
                165                 170                 175     


Trp Ala Thr Ala Arg Pro Arg Ala Ser Gly Glu Ala Gly Pro Gly Arg 
            180                 185                 190         


Ala Leu Val Gly Ala Asp Ala Ala Cys Cys Pro Arg His Ser Val Leu 
        195                 200                 205             


Ser Leu Val Asp Ile Pro Ser Gly Gln Val Leu Pro Gln Gly Gln 
    210                 215                 220             


<210>  1183
<211>  285
<212>  PRT
<213>  Human

<400>  1183

Met Glu Val Pro Pro Pro Ala Pro Arg Ser Phe Leu Cys Arg Ala Leu 
1               5                   10                  15      


Cys Leu Phe Pro Arg Val Phe Ala Ala Glu Ala Val Thr Ala Asp Ser 
            20                  25                  30          


Glu Val Leu Glu Glu Arg Gln Lys Arg Leu Pro Tyr Val Pro Glu Pro 
        35                  40                  45              


Tyr Tyr Pro Glu Ser Gly Trp Asp Arg Leu Arg Glu Leu Phe Gly Lys 
    50                  55                  60                  


Asp Glu Gln Gln Arg Ile Ser Lys Asp Leu Ala Asn Ile Cys Lys Thr 
65                  70                  75                  80  


Ala Ala Thr Ala Gly Ile Ile Gly Trp Val Tyr Gly Gly Ile Pro Ala 
                85                  90                  95      


Phe Ile His Ala Lys Gln Gln Tyr Ile Glu Gln Ser Gln Ala Glu Ile 
            100                 105                 110         


Tyr His Asn Arg Phe Asp Ala Val Gln Ser Ala His Arg Ala Ala Thr 
        115                 120                 125             


Arg Gly Phe Ile Arg Tyr Gly Trp Arg Trp Gly Trp Arg Thr Ala Val 
    130                 135                 140                 


Phe Val Thr Ile Phe Asn Thr Val Asn Thr Ser Leu Asn Val Tyr Arg 
145                 150                 155                 160 


Asn Lys Asp Ala Leu Ser His Phe Val Ile Ala Gly Ala Val Thr Gly 
                165                 170                 175     


Ser Leu Phe Arg Ile Asn Val Gly Leu Arg Gly Leu Val Ala Gly Gly 
            180                 185                 190         


Ile Ile Gly Ala Leu Leu Gly Thr Pro Val Gly Gly Leu Leu Met Ala 
        195                 200                 205             


Phe Gln Lys Tyr Ser Gly Glu Thr Val Gln Glu Arg Lys Gln Lys Asp 
    210                 215                 220                 


Arg Lys Ala Leu His Glu Leu Lys Leu Glu Glu Trp Lys Gly Arg Leu 
225                 230                 235                 240 


Gln Val Thr Glu His Leu Pro Glu Lys Ile Glu Ser Ser Leu Gln Glu 
                245                 250                 255     


Asp Glu Pro Glu Asn Asp Ala Lys Lys Ile Glu Ala Leu Leu Asn Leu 
            260                 265                 270         


Pro Arg Asn Pro Ser Val Ile Asp Lys Gln Asp Lys Asp 
        275                 280                 285 


<210>  1184
<211>  224
<212>  PRT
<213>  Human

<400>  1184

Met Ser Val Phe Gly Lys Leu Phe Gly Ala Gly Gly Gly Lys Ala Gly 
1               5                   10                  15      


Lys Gly Gly Pro Thr Pro Gln Glu Ala Ile Gln Arg Leu Arg Asp Thr 
            20                  25                  30          


Glu Glu Met Leu Ser Lys Lys Gln Glu Phe Leu Glu Lys Lys Ile Glu 
        35                  40                  45              


Gln Glu Leu Thr Ala Ala Lys Lys His Gly Thr Lys Asn Lys Arg Ala 
    50                  55                  60                  


Ala Leu Gln Ala Leu Lys Arg Lys Lys Arg Tyr Glu Lys Gln Leu Ala 
65                  70                  75                  80  


Gln Ile Asp Gly Thr Leu Ser Thr Ile Glu Phe Gln Arg Glu Ala Leu 
                85                  90                  95      


Glu Asn Ala Asn Thr Asn Thr Glu Val Leu Lys Asn Met Gly Tyr Ala 
            100                 105                 110         


Ala Lys Ala Met Lys Ala Ala His Asp Asn Met Asp Ile Asp Lys Val 
        115                 120                 125             


Asp Glu Leu Met Gln Asp Ile Ala Asp Gln Gln Glu Leu Ala Glu Glu 
    130                 135                 140                 


Ile Ser Thr Ala Ile Ser Lys Pro Val Gly Phe Gly Glu Glu Phe Asp 
145                 150                 155                 160 


Glu Asp Glu Leu Met Ala Glu Leu Glu Glu Leu Glu Gln Glu Glu Leu 
                165                 170                 175     


Asp Lys Asn Leu Leu Glu Ile Ser Gly Pro Glu Thr Val Pro Leu Pro 
            180                 185                 190         


Asn Val Pro Ser Ile Ala Leu Pro Ser Lys Pro Ala Lys Lys Lys Glu 
        195                 200                 205             


Glu Glu Asp Asp Asp Met Lys Glu Leu Glu Asn Trp Ala Gly Ser Met 
    210                 215                 220                 


<210>  1185
<211>  1608
<212>  PRT
<213>  Human

<400>  1185

Met Tyr Ser Ala His Arg Pro Leu Met Pro Ala Ser Ser Ala Ala Ser 
1               5                   10                  15      


Arg Gly Leu Gly Met Phe Val Trp Thr Asn Val Glu Pro Arg Ser Val 
            20                  25                  30          


Ala Val Phe Pro Trp His Ser Leu Val Pro Phe Leu Ala Pro Ser Gln 
        35                  40                  45              


Pro Asp Pro Ser Val Gln Pro Ser Glu Ala Gln Gln Pro Ala Ser His 
    50                  55                  60                  


Pro Val Ala Ser Asn Gln Ser Lys Glu Pro Ala Glu Ser Ala Ala Val 
65                  70                  75                  80  


Ala His Glu Arg Pro Pro Gly Gly Thr Gly Ser Ala Asp Pro Glu Arg 
                85                  90                  95      


Pro Pro Gly Ala Thr Cys Pro Glu Ser Pro Gly Pro Gly Pro Pro His 
            100                 105                 110         


Pro Leu Gly Val Val Glu Ser Gly Lys Gly Pro Pro Pro Thr Thr Glu 
        115                 120                 125             


Glu Glu Ala Ser Gly Pro Pro Gly Glu Pro Arg Leu Asp Ser Glu Thr 
    130                 135                 140                 


Glu Ser Asp His Asp Asp Ala Phe Leu Ser Ile Met Ser Pro Glu Ile 
145                 150                 155                 160 


Gln Leu Pro Leu Pro Pro Gly Lys Arg Arg Thr Gln Ser Leu Ser Ala 
                165                 170                 175     


Leu Pro Lys Glu Arg Asp Ser Ser Ser Glu Lys Asp Gly Arg Ser Pro 
            180                 185                 190         


Asn Lys Arg Glu Lys Asp His Ile Arg Arg Pro Met Asn Ala Phe Met 
        195                 200                 205             


Ile Phe Ser Lys Arg His Arg Ala Leu Val His Gln Arg His Pro Asn 
    210                 215                 220                 


Gln Asp Asn Arg Thr Val Ser Lys Ile Leu Gly Glu Trp Trp Tyr Ala 
225                 230                 235                 240 


Leu Gly Pro Lys Glu Lys Gln Lys Tyr His Asp Leu Ala Phe Gln Val 
                245                 250                 255     


Lys Glu Ala His Phe Lys Ala His Pro Asp Trp Lys Trp Cys Asn Lys 
            260                 265                 270         


Asp Arg Lys Lys Ser Ser Ser Glu Ala Lys Pro Thr Ser Leu Gly Leu 
        275                 280                 285             


Ala Gly Gly His Lys Glu Thr Arg Glu Arg Ser Met Ser Glu Thr Gly 
    290                 295                 300                 


Thr Ala Ala Ala Pro Gly Val Ser Ser Glu Leu Leu Ser Val Ala Ala 
305                 310                 315                 320 


Gln Thr Leu Leu Ser Ser Asp Thr Lys Ala Pro Gly Ser Ser Ser Cys 
                325                 330                 335     


Gly Ala Glu Arg Leu His Thr Val Gly Gly Pro Gly Ser Ala Arg Pro 
            340                 345                 350         


Arg Ala Phe Ser His Ser Gly Val His Ser Leu Asp Gly Gly Glu Val 
        355                 360                 365             


Asp Ser Gln Ala Leu Gln Glu Leu Thr Gln Met Val Ser Gly Pro Ala 
    370                 375                 380                 


Ser Tyr Ser Gly Pro Lys Pro Ser Thr Gln Tyr Gly Ala Pro Gly Pro 
385                 390                 395                 400 


Phe Ala Ala Pro Gly Glu Gly Gly Ala Leu Ala Ala Thr Gly Arg Pro 
                405                 410                 415     


Pro Leu Leu Pro Thr Arg Ala Ser Arg Ser Gln Arg Ala Ala Ser Glu 
            420                 425                 430         


Asp Met Thr Ser Asp Glu Glu Arg Met Val Ile Cys Glu Glu Glu Gly 
        435                 440                 445             


Asp Asp Asp Val Ile Ala Asp Asp Gly Phe Gly Thr Thr Asp Ile Asp 
    450                 455                 460                 


Leu Lys Cys Lys Glu Arg Val Thr Asp Ser Glu Ser Gly Asp Ser Ser 
465                 470                 475                 480 


Gly Glu Asp Pro Glu Gly Asn Lys Gly Phe Gly Arg Lys Val Phe Ser 
                485                 490                 495     


Pro Val Ile Arg Ser Ser Phe Thr His Cys Arg Pro Pro Leu Asp Pro 
            500                 505                 510         


Glu Pro Pro Gly Pro Pro Asp Pro Pro Val Ala Phe Gly Lys Gly Tyr 
        515                 520                 525             


Gly Ser Ala Pro Ser Ser Ser Ala Ser Ser Pro Ala Ser Ser Ser Ala 
    530                 535                 540                 


Ser Ala Ala Thr Ser Phe Ser Leu Gly Ser Gly Thr Phe Lys Ala Gln 
545                 550                 555                 560 


Glu Ser Gly Gln Gly Ser Thr Ala Gly Pro Leu Arg Pro Pro Pro Pro 
                565                 570                 575     


Gly Ala Gly Gly Pro Ala Thr Pro Ser Lys Ala Thr Arg Phe Leu Pro 
            580                 585                 590         


Met Asp Pro Ala Thr Phe Arg Arg Lys Arg Pro Glu Ser Val Gly Gly 
        595                 600                 605             


Leu Glu Pro Pro Gly Pro Ser Val Ile Ala Ala Pro Pro Ser Gly Gly 
    610                 615                 620                 


Gly Asn Ile Leu Gln Thr Leu Val Leu Pro Pro Asn Lys Glu Glu Gln 
625                 630                 635                 640 


Glu Gly Gly Gly Ala Arg Val Pro Ser Ala Pro Ala Pro Ser Leu Ala 
                645                 650                 655     


Tyr Gly Ala Pro Ala Ala Pro Leu Ser Arg Pro Ala Ala Thr Met Val 
            660                 665                 670         


Thr Asn Val Val Arg Pro Val Ser Ser Thr Pro Val Pro Ile Ala Ser 
        675                 680                 685             


Lys Pro Phe Pro Thr Ser Gly Arg Ala Glu Ala Ser Pro Asn Asp Thr 
    690                 695                 700                 


Ala Gly Ala Arg Thr Glu Met Gly Thr Gly Ser Arg Val Pro Gly Gly 
705                 710                 715                 720 


Ser Pro Leu Gly Val Ser Leu Val Tyr Ser Asp Lys Lys Ser Ala Ala 
                725                 730                 735     


Ala Thr Ser Pro Ala Pro His Leu Val Ala Gly Pro Leu Leu Gly Thr 
            740                 745                 750         


Val Gly Lys Ala Pro Ala Thr Val Thr Asn Leu Leu Val Gly Thr Pro 
        755                 760                 765             


Gly Tyr Gly Ala Pro Ala Pro Pro Ala Val Gln Phe Ile Ala Gln Gly 
    770                 775                 780                 


Ala Pro Gly Gly Gly Thr Thr Ala Gly Ser Gly Ala Gly Ala Gly Ser 
785                 790                 795                 800 


Gly Pro Asn Gly Pro Val Pro Leu Gly Ile Leu Gln Pro Gly Ala Leu 
                805                 810                 815     


Gly Lys Ala Gly Gly Ile Thr Gln Val Gln Tyr Ile Leu Pro Thr Leu 
            820                 825                 830         


Pro Gln Gln Leu Gln Val Ala Pro Ala Pro Ala Pro Ala Pro Gly Thr 
        835                 840                 845             


Lys Ala Ala Ala Pro Ser Gly Pro Ala Pro Thr Thr Ser Ile Arg Phe 
    850                 855                 860                 


Thr Leu Pro Pro Gly Thr Ser Thr Asn Gly Lys Val Leu Ala Ala Thr 
865                 870                 875                 880 


Ala Pro Thr Pro Gly Ile Pro Ile Leu Gln Ser Val Pro Ser Ala Pro 
                885                 890                 895     


Pro Pro Lys Ala Gln Ser Val Ser Pro Val Gln Ala Pro Pro Pro Gly 
            900                 905                 910         


Gly Ser Ala Gln Leu Leu Pro Gly Lys Val Leu Val Pro Leu Ala Ala 
        915                 920                 925             


Pro Ser Met Ser Val Arg Gly Gly Gly Ala Gly Gln Pro Leu Pro Leu 
    930                 935                 940                 


Val Ser Pro Pro Phe Ser Val Pro Val Gln Asn Gly Ala Gln Pro Pro 
945                 950                 955                 960 


Ser Lys Ile Ile Gln Leu Thr Pro Val Pro Val Ser Thr Pro Ser Gly 
                965                 970                 975     


Leu Val Pro Pro Leu Ser Pro Ala Thr Leu Pro Gly Pro Thr Ser Gln 
            980                 985                 990         


Pro Gln Lys Val Leu Leu Pro Ser  Ser Thr Arg Ile Thr  Tyr Val Gln 
        995                 1000                 1005             


Ser Ala  Gly Gly His Ala Leu  Pro Leu Gly Thr Ser  Pro Ala Ser 
    1010                 1015                 1020             


Ser Gln  Ala Gly Thr Val Thr  Ser Tyr Gly Pro Thr  Ser Ser Val 
    1025                 1030                 1035             


Ala Leu  Gly Phe Thr Ser Leu  Gly Pro Ser Gly Pro  Ala Phe Val 
    1040                 1045                 1050             


Gln Pro  Leu Leu Ser Ala Gly  Gln Ala Pro Leu Leu  Ala Pro Gly 
    1055                 1060                 1065             


Gln Val  Gly Val Ser Pro Val  Pro Ser Pro Gln Leu  Pro Pro Ala 
    1070                 1075                 1080             


Cys Ala  Ala Pro Gly Gly Pro  Val Ile Thr Ala Phe  Tyr Ser Gly 
    1085                 1090                 1095             


Ser Pro  Ala Pro Thr Ser Ser  Ala Pro Leu Ala Gln  Pro Ser Gln 
    1100                 1105                 1110             


Ala Pro  Pro Ser Leu Val Tyr  Thr Val Ala Thr Ser  Thr Thr Pro 
    1115                 1120                 1125             


Pro Ala  Ala Thr Ile Leu Pro  Lys Gly Pro Pro Ala  Pro Ala Thr 
    1130                 1135                 1140             


Ala Thr  Pro Ala Pro Thr Ser  Pro Phe Pro Ser Ala  Thr Ala Gly 
    1145                 1150                 1155             


Ser Met  Thr Tyr Ser Leu Val  Ala Pro Lys Ala Gln  Arg Pro Ser 
    1160                 1165                 1170             


Pro Lys  Ala Pro Gln Lys Val  Lys Ala Ala Ile Ala  Ser Ile Pro 
    1175                 1180                 1185             


Val Gly  Ser Phe Glu Ala Gly  Ala Ser Gly Arg Pro  Gly Pro Ala 
    1190                 1195                 1200             


Pro Arg  Gln Pro Leu Glu Pro  Gly Pro Val Arg Glu  Pro Thr Ala 
    1205                 1210                 1215             


Pro Glu  Ser Glu Leu Glu Gly  Gln Pro Thr Pro Pro  Ala Pro Pro 
    1220                 1225                 1230             


Pro Leu  Pro Glu Thr Trp Thr  Pro Thr Ala Arg Ser  Ser Pro Pro 
    1235                 1240                 1245             


Leu Pro  Pro Pro Ala Glu Glu  Arg Thr Ser Ala Lys  Gly Pro Glu 
    1250                 1255                 1260             


Thr Met  Ala Ser Lys Phe Pro  Ser Ser Ser Ser Asp  Trp Arg Val 
    1265                 1270                 1275             


Pro Gly  Gln Gly Leu Glu Asn  Arg Gly Glu Pro Pro  Thr Pro Pro 
    1280                 1285                 1290             


Ser Pro  Ala Pro Ala Pro Ala  Val Ala Pro Gly Gly  Ser Ser Glu 
    1295                 1300                 1305             


Ser Ser  Ser Gly Arg Ala Ala  Gly Asp Thr Pro Glu  Arg Lys Glu 
    1310                 1315                 1320             


Ala Ala  Gly Thr Gly Lys Lys  Val Lys Val Arg Pro  Pro Pro Leu 
    1325                 1330                 1335             


Lys Lys  Thr Phe Asp Ser Val  Asp Asn Arg Val Leu  Ser Glu Val 
    1340                 1345                 1350             


Asp Phe  Glu Glu Arg Phe Ala  Glu Leu Pro Glu Phe  Arg Pro Glu 
    1355                 1360                 1365             


Glu Val  Leu Pro Ser Pro Thr  Leu Gln Ser Leu Ala  Thr Ser Pro 
    1370                 1375                 1380             


Arg Ala  Ile Leu Gly Ser Tyr  Arg Lys Lys Arg Lys  Asn Ser Thr 
    1385                 1390                 1395             


Asp Leu  Asp Ser Ala Pro Glu  Asp Pro Thr Ser Pro  Lys Arg Lys 
    1400                 1405                 1410             


Met Arg  Arg Arg Ser Ser Cys  Ser Ser Glu Pro Asn  Thr Pro Lys 
    1415                 1420                 1425             


Ser Ala  Lys Cys Glu Gly Asp  Ile Phe Thr Phe Asp  Arg Thr Gly 
    1430                 1435                 1440             


Thr Glu  Ala Glu Asp Val Leu  Gly Glu Leu Glu Tyr  Asp Lys Val 
    1445                 1450                 1455             


Pro Tyr  Ser Ser Leu Arg Arg  Thr Leu Asp Gln Arg  Arg Ala Leu 
    1460                 1465                 1470             


Val Met  Gln Leu Phe Gln Asp  His Gly Phe Phe Pro  Ser Ala Gln 
    1475                 1480                 1485             


Ala Thr  Ala Ala Phe Gln Ala  Arg Tyr Ala Asp Ile  Phe Pro Ser 
    1490                 1495                 1500             


Lys Val  Cys Leu Gln Leu Lys  Ile Arg Glu Val Arg  Gln Lys Ile 
    1505                 1510                 1515             


Met Gln  Ala Ala Thr Pro Thr  Glu Gln Pro Pro Gly  Ala Glu Ala 
    1520                 1525                 1530             


Pro Leu  Pro Val Pro Pro Pro  Thr Gly Thr Ala Ala  Ala Pro Ala 
    1535                 1540                 1545             


Pro Thr  Pro Ser Pro Ala Gly  Gly Pro Asp Pro Thr  Ser Pro Ser 
    1550                 1555                 1560             


Ser Asp  Ser Gly Thr Ala Gln  Ala Ala Pro Pro Leu  Pro Pro Pro 
    1565                 1570                 1575             


Pro Glu  Ser Gly Pro Gly Gln  Pro Gly Trp Glu Gly  Ala Pro Gln 
    1580                 1585                 1590             


Pro Ser  Pro Pro Pro Pro Gly  Pro Ser Thr Ala Ala  Thr Gly Arg 
    1595                 1600                 1605             


<210>  1186
<211>  602
<212>  PRT
<213>  Human

<400>  1186

Met Pro Ser Ala Lys Gln Arg Gly Ser Lys Gly Gly His Gly Ala Ala 
1               5                   10                  15      


Ser Pro Ser Glu Lys Gly Ala His Pro Ser Gly Gly Ala Asp Asp Val 
            20                  25                  30          


Ala Lys Lys Pro Pro Pro Ala Pro Gln Gln Pro Pro Pro Pro Pro Ala 
        35                  40                  45              


Pro His Pro Gln Gln His Pro Gln Gln His Pro Gln Asn Gln Ala His 
    50                  55                  60                  


Gly Lys Gly Gly His Arg Gly Gly Gly Gly Gly Gly Gly Lys Ser Ser 
65                  70                  75                  80  


Ser Ser Ser Ser Ala Ser Ala Ala Ala Ala Ala Ala Ala Ala Ser Ser 
                85                  90                  95      


Ser Ala Ser Cys Ser Arg Arg Leu Gly Arg Ala Leu Asn Phe Leu Phe 
            100                 105                 110         


Tyr Leu Ala Leu Val Ala Ala Ala Ala Phe Ser Gly Trp Cys Val His 
        115                 120                 125             


His Val Leu Glu Glu Val Gln Gln Val Arg Arg Ser His Gln Asp Phe 
    130                 135                 140                 


Ser Arg Gln Arg Glu Glu Leu Gly Gln Gly Leu Gln Gly Val Glu Gln 
145                 150                 155                 160 


Lys Val Gln Ser Leu Gln Ala Thr Phe Gly Thr Phe Glu Ser Ile Leu 
                165                 170                 175     


Arg Ser Ser Gln His Lys Gln Asp Leu Thr Glu Lys Ala Val Lys Gln 
            180                 185                 190         


Gly Glu Ser Glu Val Ser Arg Ile Ser Glu Val Leu Gln Lys Leu Gln 
        195                 200                 205             


Asn Glu Ile Leu Lys Asp Leu Ser Asp Gly Ile His Val Val Lys Asp 
    210                 215                 220                 


Ala Arg Glu Arg Asp Phe Thr Ser Leu Glu Asn Thr Val Glu Glu Arg 
225                 230                 235                 240 


Leu Thr Glu Leu Thr Lys Ser Ile Asn Asp Asn Ile Ala Ile Phe Thr 
                245                 250                 255     


Glu Val Gln Lys Arg Ser Gln Lys Glu Ile Asn Asp Met Lys Ala Lys 
            260                 265                 270         


Val Ala Ser Leu Glu Glu Ser Glu Gly Asn Lys Gln Asp Leu Lys Ala 
        275                 280                 285             


Leu Lys Glu Ala Val Lys Glu Ile Gln Thr Ser Ala Lys Ser Arg Glu 
    290                 295                 300                 


Trp Asp Met Glu Ala Leu Arg Ser Thr Leu Gln Thr Met Glu Ser Asp 
305                 310                 315                 320 


Ile Tyr Thr Glu Val Arg Glu Leu Val Ser Leu Lys Gln Glu Gln Gln 
                325                 330                 335     


Ala Phe Lys Glu Ala Ala Asp Thr Glu Arg Leu Ala Leu Gln Ala Leu 
            340                 345                 350         


Thr Glu Lys Leu Leu Arg Ser Glu Glu Ser Val Ser Arg Leu Pro Glu 
        355                 360                 365             


Glu Ile Arg Arg Leu Glu Glu Glu Leu Arg Gln Leu Lys Ser Asp Ser 
    370                 375                 380                 


His Gly Pro Lys Glu Asp Gly Gly Phe Arg His Ser Glu Ala Phe Glu 
385                 390                 395                 400 


Ala Leu Gln Gln Lys Ser Gln Gly Leu Asp Ser Arg Leu Gln His Val 
                405                 410                 415     


Glu Asp Gly Val Leu Ser Met Gln Val Ala Ser Ala Arg Gln Thr Glu 
            420                 425                 430         


Ser Leu Glu Ser Leu Leu Ser Lys Ser Gln Glu His Glu Gln Arg Leu 
        435                 440                 445             


Ala Ala Leu Gln Gly Arg Leu Glu Gly Leu Gly Ser Ser Glu Ala Asp 
    450                 455                 460                 


Gln Asp Gly Leu Ala Ser Thr Val Arg Ser Leu Gly Glu Thr Gln Leu 
465                 470                 475                 480 


Val Leu Tyr Gly Asp Val Glu Glu Leu Lys Arg Ser Val Gly Glu Leu 
                485                 490                 495     


Pro Ser Thr Val Glu Ser Leu Gln Lys Val Gln Glu Gln Val His Thr 
            500                 505                 510         


Leu Leu Ser Gln Asp Gln Ala Gln Ala Ala Arg Leu Pro Pro Gln Asp 
        515                 520                 525             


Phe Leu Asp Arg Leu Ser Ser Leu Asp Asn Leu Lys Ala Ser Val Ser 
    530                 535                 540                 


Gln Val Glu Ala Asp Leu Lys Met Leu Arg Thr Ala Val Asp Ser Leu 
545                 550                 555                 560 


Val Ala Tyr Ser Val Lys Ile Glu Thr Asn Glu Asn Asn Leu Glu Ser 
                565                 570                 575     


Ala Lys Gly Leu Leu Asp Asp Leu Arg Asn Asp Leu Asp Arg Leu Phe 
            580                 585                 590         


Val Lys Val Glu Lys Ile His Glu Lys Val 
        595                 600         


<210>  1187
<211>  1506
<212>  PRT
<213>  Human

<400>  1187

Met Glu Pro Arg Ser Met Glu Tyr Phe Cys Ala Gln Val Gln Gln Lys 
1               5                   10                  15      


Asp Val Gly Gly Arg Leu Gln Val Gly Gln Glu Leu Leu Leu Tyr Leu 
            20                  25                  30          


Gly Ala Pro Gly Ala Ile Ser Asp Leu Glu Glu Asp Leu Gly Arg Leu 
        35                  40                  45              


Gly Lys Thr Val Asp Ala Leu Thr Gly Trp Val Gly Ser Ser Asn Tyr 
    50                  55                  60                  


Arg Val Ser Leu Met Gly Leu Glu Ile Leu Ser Ala Phe Val Asp Arg 
65                  70                  75                  80  


Leu Ser Thr Arg Phe Lys Ser Tyr Val Ala Met Val Ile Val Ala Leu 
                85                  90                  95      


Ile Asp Arg Met Gly Asp Ala Lys Asp Lys Val Arg Asp Glu Ala Gln 
            100                 105                 110         


Thr Leu Ile Leu Lys Leu Met Asp Gln Val Ala Pro Pro Met Tyr Ile 
        115                 120                 125             


Trp Glu Gln Leu Ala Ser Gly Phe Lys His Lys Asn Phe Arg Ser Arg 
    130                 135                 140                 


Glu Gly Val Cys Leu Cys Leu Ile Glu Thr Leu Asn Ile Phe Gly Ala 
145                 150                 155                 160 


Gln Pro Leu Val Ile Ser Lys Leu Ile Pro His Leu Cys Ile Leu Phe 
                165                 170                 175     


Gly Asp Ser Asn Ser Gln Val Arg Asp Ala Ala Ile Leu Ala Ile Val 
            180                 185                 190         


Glu Ile Tyr Arg His Val Gly Glu Lys Val Arg Met Asp Leu Tyr Lys 
        195                 200                 205             


Arg Gly Ile Pro Pro Ala Arg Leu Glu Met Ile Phe Ala Lys Phe Asp 
    210                 215                 220                 


Glu Val Gln Ser Ser Gly Gly Met Ile Leu Ser Val Cys Lys Asp Lys 
225                 230                 235                 240 


Ser Phe Asp Asp Glu Glu Ser Val Asp Gly Asn Arg Pro Ser Ser Ala 
                245                 250                 255     


Ala Ser Ala Phe Lys Val Pro Ala Pro Lys Thr Ser Gly Asn Pro Ala 
            260                 265                 270         


Asn Ser Ala Arg Lys Pro Gly Ser Ala Gly Gly Pro Lys Val Gly Gly 
        275                 280                 285             


Ala Ser Lys Glu Gly Gly Ala Gly Ala Val Asp Glu Asp Asp Phe Ile 
    290                 295                 300                 


Lys Ala Phe Thr Asp Val Pro Ser Ile Gln Ile Tyr Ser Ser Arg Glu 
305                 310                 315                 320 


Leu Glu Glu Thr Leu Asn Lys Ile Arg Glu Ile Leu Ser Asp Asp Lys 
                325                 330                 335     


His Asp Trp Asp Gln Arg Ala Asn Ala Leu Lys Lys Ile Arg Ser Leu 
            340                 345                 350         


Leu Val Ala Gly Ala Ala Gln Tyr Asp Cys Phe Phe Gln His Leu Arg 
        355                 360                 365             


Leu Leu Asp Gly Ala Leu Lys Leu Ser Ala Lys Asp Leu Arg Ser Gln 
    370                 375                 380                 


Val Val Arg Glu Ala Cys Ile Thr Val Ala His Leu Ser Thr Val Leu 
385                 390                 395                 400 


Gly Asn Lys Phe Asp His Gly Ala Glu Ala Ile Val Pro Thr Leu Phe 
                405                 410                 415     


Asn Leu Val Pro Asn Ser Ala Lys Val Met Ala Thr Ser Gly Cys Ala 
            420                 425                 430         


Ala Ile Arg Phe Ile Ile Arg His Thr His Val Pro Arg Leu Ile Pro 
        435                 440                 445             


Leu Ile Thr Ser Asn Cys Thr Ser Lys Ser Val Pro Val Arg Arg Arg 
    450                 455                 460                 


Ser Phe Glu Phe Leu Asp Leu Leu Leu Gln Glu Trp Gln Thr His Ser 
465                 470                 475                 480 


Leu Glu Arg His Ala Ala Val Leu Val Glu Thr Ile Lys Lys Gly Ile 
                485                 490                 495     


His Asp Ala Asp Ala Glu Ala Arg Val Glu Ala Arg Lys Thr Tyr Met 
            500                 505                 510         


Gly Leu Arg Asn His Phe Pro Gly Glu Ala Glu Thr Leu Tyr Asn Ser 
        515                 520                 525             


Leu Glu Pro Ser Tyr Gln Lys Ser Leu Gln Thr Tyr Leu Lys Ser Ser 
    530                 535                 540                 


Gly Ser Val Ala Ser Leu Pro Gln Ser Asp Arg Ser Ser Ser Ser Ser 
545                 550                 555                 560 


Gln Glu Ser Leu Asn Arg Pro Phe Ser Ser Lys Trp Ser Thr Ala Asn 
                565                 570                 575     


Pro Ser Thr Val Ala Gly Arg Val Ser Ala Gly Ser Ser Lys Ala Ser 
            580                 585                 590         


Ser Leu Pro Gly Ser Leu Gln Arg Ser Arg Ser Asp Ile Asp Val Asn 
        595                 600                 605             


Ala Ala Ala Gly Ala Lys Ala His His Ala Ala Gly Gln Ser Val Arg 
    610                 615                 620                 


Ser Gly Arg Leu Gly Ala Gly Ala Leu Asn Ala Gly Ser Tyr Ala Ser 
625                 630                 635                 640 


Leu Glu Asp Thr Ser Asp Lys Leu Asp Gly Thr Ala Ser Glu Asp Gly 
                645                 650                 655     


Arg Val Arg Ala Lys Leu Ser Ala Pro Leu Ala Gly Met Gly Asn Ala 
            660                 665                 670         


Lys Ala Asp Ser Arg Gly Arg Ser Arg Thr Lys Met Val Ser Gln Ser 
        675                 680                 685             


Gln Pro Gly Ser Arg Ser Gly Ser Pro Gly Arg Val Leu Thr Thr Thr 
    690                 695                 700                 


Ala Leu Ser Thr Val Ser Ser Gly Val Gln Arg Val Leu Val Asn Ser 
705                 710                 715                 720 


Ala Ser Ala Gln Lys Arg Ser Lys Ile Pro Arg Ser Gln Gly Cys Ser 
                725                 730                 735     


Arg Glu Ala Ser Pro Ser Arg Leu Ser Val Ala Arg Ser Ser Arg Ile 
            740                 745                 750         


Pro Arg Pro Ser Val Ser Gln Gly Cys Ser Arg Glu Ala Ser Arg Glu 
        755                 760                 765             


Ser Ser Arg Asp Thr Ser Pro Val Arg Ser Phe Gln Pro Leu Gly Pro 
    770                 775                 780                 


Gly Tyr Gly Ile Ser Gln Ser Ser Arg Leu Ser Ser Ser Val Ser Ala 
785                 790                 795                 800 


Met Arg Val Leu Asn Thr Gly Ser Asp Val Glu Glu Ala Val Ala Asp 
                805                 810                 815     


Ala Leu Lys Lys Pro Ala Arg Arg Arg Tyr Glu Ser Tyr Gly Met His 
            820                 825                 830         


Ser Asp Asp Asp Ala Asn Ser Asp Ala Ser Ser Ala Cys Ser Glu Arg 
        835                 840                 845             


Ser Tyr Ser Ser Arg Asn Gly Ser Ile Pro Thr Tyr Met Arg Gln Thr 
    850                 855                 860                 


Glu Asp Val Ala Glu Val Leu Asn Arg Cys Ala Ser Ser Asn Trp Ser 
865                 870                 875                 880 


Glu Arg Lys Glu Gly Leu Leu Gly Leu Gln Asn Leu Leu Lys Asn Gln 
                885                 890                 895     


Arg Thr Leu Ser Arg Val Glu Leu Lys Arg Leu Cys Glu Ile Phe Thr 
            900                 905                 910         


Arg Met Phe Ala Asp Pro His Gly Lys Arg Val Phe Ser Met Phe Leu 
        915                 920                 925             


Glu Thr Leu Val Asp Phe Ile Gln Val His Lys Asp Asp Leu Gln Asp 
    930                 935                 940                 


Trp Leu Phe Val Leu Leu Thr Gln Leu Leu Lys Lys Met Gly Ala Asp 
945                 950                 955                 960 


Leu Leu Gly Ser Val Gln Ala Lys Val Gln Lys Ala Leu Asp Val Thr 
                965                 970                 975     


Arg Glu Ser Phe Pro Asn Asp Leu Gln Phe Asn Ile Leu Met Arg Phe 
            980                 985                 990         


Thr Val Asp Gln Thr Gln Thr Pro  Ser Leu Lys Val Lys  Val Ala Ile 
        995                 1000                 1005             


Leu Lys  Tyr Ile Glu Thr Leu  Ala Lys Gln Met Asp  Pro Gly Asp 
    1010                 1015                 1020             


Phe Ile  Asn Ser Ser Glu Thr  Arg Leu Ala Val Ser  Arg Val Ile 
    1025                 1030                 1035             


Thr Trp  Thr Thr Glu Pro Lys  Ser Ser Asp Val Arg  Lys Ala Ala 
    1040                 1045                 1050             


Gln Ser  Val Leu Ile Ser Leu  Phe Glu Leu Asn Thr  Pro Glu Phe 
    1055                 1060                 1065             


Thr Met  Leu Leu Gly Ala Leu  Pro Lys Thr Phe Gln  Asp Gly Ala 
    1070                 1075                 1080             


Thr Lys  Leu Leu His Asn His  Leu Arg Asn Thr Gly  Asn Gly Thr 
    1085                 1090                 1095             


Gln Ser  Ser Met Gly Ser Pro  Leu Thr Arg Pro Thr  Pro Arg Ser 
    1100                 1105                 1110             


Pro Ala  Asn Trp Ser Ser Pro  Leu Thr Ser Pro Thr  Asn Thr Ser 
    1115                 1120                 1125             


Gln Asn  Thr Leu Ser Pro Ser  Ala Phe Asp Tyr Asp  Thr Glu Asn 
    1130                 1135                 1140             


Met Asn  Ser Glu Asp Ile Tyr  Ser Ser Leu Arg Gly  Val Thr Glu 
    1145                 1150                 1155             


Ala Ile  Gln Asn Phe Ser Phe  Arg Ser Gln Glu Asp  Met Asn Glu 
    1160                 1165                 1170             


Pro Leu  Lys Arg Asp Ser Lys  Lys Asp Asp Gly Asp  Ser Met Cys 
    1175                 1180                 1185             


Gly Gly  Pro Gly Met Ser Asp  Pro Arg Ala Gly Gly  Asp Ala Thr 
    1190                 1195                 1200             


Asp Ser  Ser Gln Thr Ala Leu  Asp Asn Lys Ala Ser  Leu Leu His 
    1205                 1210                 1215             


Ser Met  Pro Thr His Ser Ser  Pro Arg Ser Arg Asp  Tyr Asn Pro 
    1220                 1225                 1230             


Tyr Asn  Tyr Ser Asp Ser Ile  Ser Pro Phe Asn Lys  Ser Ala Leu 
    1235                 1240                 1245             


Lys Glu  Ala Met Phe Asp Asp  Asp Ala Asp Gln Phe  Pro Asp Asp 
    1250                 1255                 1260             


Leu Ser  Leu Asp His Ser Asp  Leu Val Ala Glu Leu  Leu Lys Glu 
    1265                 1270                 1275             


Leu Ser  Asn His Asn Glu Arg  Val Glu Glu Arg Lys  Ile Ala Leu 
    1280                 1285                 1290             


Tyr Glu  Leu Met Lys Leu Thr  Gln Glu Glu Ser Phe  Ser Val Trp 
    1295                 1300                 1305             


Asp Glu  His Phe Lys Thr Ile  Leu Leu Leu Leu Leu  Glu Thr Leu 
    1310                 1315                 1320             


Gly Asp  Lys Glu Pro Thr Ile  Arg Ala Leu Ala Leu  Lys Val Leu 
    1325                 1330                 1335             


Arg Glu  Ile Leu Arg His Gln  Pro Ala Arg Phe Lys  Asn Tyr Ala 
    1340                 1345                 1350             


Glu Leu  Thr Val Met Lys Thr  Leu Glu Ala His Lys  Asp Pro His 
    1355                 1360                 1365             


Lys Glu  Val Val Arg Ser Ala  Glu Glu Ala Ala Ser  Val Leu Ala 
    1370                 1375                 1380             


Thr Ser  Ile Ser Pro Glu Gln  Cys Ile Lys Val Leu  Cys Pro Ile 
    1385                 1390                 1395             


Ile Gln  Thr Ala Asp Tyr Pro  Ile Asn Leu Ala Ala  Ile Lys Met 
    1400                 1405                 1410             


Gln Thr  Lys Val Ile Glu Arg  Val Ser Lys Glu Thr  Leu Asn Leu 
    1415                 1420                 1425             


Leu Leu  Pro Glu Ile Met Pro  Gly Leu Ile Gln Gly  Tyr Asp Asn 
    1430                 1435                 1440             


Ser Glu  Ser Ser Val Arg Lys  Ala Cys Val Phe Cys  Leu Val Ala 
    1445                 1450                 1455             


Val His  Ala Val Ile Gly Asp  Glu Leu Lys Pro His  Leu Ser Gln 
    1460                 1465                 1470             


Leu Thr  Gly Ser Lys Met Lys  Leu Leu Asn Leu Tyr  Ile Lys Arg 
    1475                 1480                 1485             


Ala Gln  Thr Gly Ser Gly Gly  Ala Asp Pro Thr Thr  Asp Val Ser 
    1490                 1495                 1500             


Gly Gln  Ser 
    1505     


<210>  1188
<211>  757
<212>  PRT
<213>  Human

<400>  1188

Met Val Pro Asp Thr Ala Cys Val Leu Leu Leu Thr Leu Ala Ala Leu 
1               5                   10                  15      


Gly Ala Ser Gly Gln Gly Gln Ser Pro Leu Gly Ser Asp Leu Gly Pro 
            20                  25                  30          


Gln Met Leu Arg Glu Leu Gln Glu Thr Asn Ala Ala Leu Gln Asp Val 
        35                  40                  45              


Arg Glu Leu Leu Arg Gln Gln Val Arg Glu Ile Thr Phe Leu Lys Asn 
    50                  55                  60                  


Thr Val Met Glu Cys Asp Ala Cys Gly Met Gln Gln Ser Val Arg Thr 
65                  70                  75                  80  


Gly Leu Pro Ser Val Arg Pro Leu Leu His Cys Ala Pro Gly Phe Cys 
                85                  90                  95      


Phe Pro Gly Val Ala Cys Ile Gln Thr Glu Ser Gly Ala Arg Cys Gly 
            100                 105                 110         


Pro Cys Pro Ala Gly Phe Thr Gly Asn Gly Ser His Cys Thr Asp Val 
        115                 120                 125             


Asn Glu Cys Asn Ala His Pro Cys Phe Pro Arg Val Arg Cys Ile Asn 
    130                 135                 140                 


Thr Ser Pro Gly Phe Arg Cys Glu Ala Cys Pro Pro Gly Tyr Ser Gly 
145                 150                 155                 160 


Pro Thr His Gln Gly Val Gly Leu Ala Phe Ala Lys Ala Asn Lys Gln 
                165                 170                 175     


Val Cys Thr Asp Ile Asn Glu Cys Glu Thr Gly Gln His Asn Cys Val 
            180                 185                 190         


Pro Asn Ser Val Cys Ile Asn Thr Arg Gly Ser Phe Gln Cys Gly Pro 
        195                 200                 205             


Cys Gln Pro Gly Phe Val Gly Asp Gln Ala Ser Gly Cys Gln Arg Arg 
    210                 215                 220                 


Ala Gln Arg Phe Cys Pro Asp Gly Ser Pro Ser Glu Cys His Glu His 
225                 230                 235                 240 


Ala Asp Cys Val Leu Glu Arg Asp Gly Ser Arg Ser Cys Val Cys Ala 
                245                 250                 255     


Val Gly Trp Ala Gly Asn Gly Ile Leu Cys Gly Arg Asp Thr Asp Leu 
            260                 265                 270         


Asp Gly Phe Pro Asp Glu Lys Leu Arg Cys Pro Glu Arg Gln Cys Arg 
        275                 280                 285             


Lys Asp Asn Cys Val Thr Val Pro Asn Ser Gly Gln Glu Asp Val Asp 
    290                 295                 300                 


Arg Asp Gly Ile Gly Asp Ala Cys Asp Pro Asp Ala Asp Gly Asp Gly 
305                 310                 315                 320 


Val Pro Asn Glu Lys Asp Asn Cys Pro Leu Val Arg Asn Pro Asp Gln 
                325                 330                 335     


Arg Asn Thr Asp Glu Asp Lys Trp Gly Asp Ala Cys Asp Asn Cys Arg 
            340                 345                 350         


Ser Gln Lys Asn Asp Asp Gln Lys Asp Thr Asp Gln Asp Gly Arg Gly 
        355                 360                 365             


Asp Ala Cys Asp Asp Asp Ile Asp Gly Asp Arg Ile Arg Asn Gln Ala 
    370                 375                 380                 


Asp Asn Cys Pro Arg Val Pro Asn Ser Asp Gln Lys Asp Ser Asp Gly 
385                 390                 395                 400 


Asp Gly Ile Gly Asp Ala Cys Asp Asn Cys Pro Gln Lys Ser Asn Pro 
                405                 410                 415     


Asp Gln Ala Asp Val Asp His Asp Phe Val Gly Asp Ala Cys Asp Ser 
            420                 425                 430         


Asp Gln Asp Gln Asp Gly Asp Gly His Gln Asp Ser Arg Asp Asn Cys 
        435                 440                 445             


Pro Thr Val Pro Asn Ser Ala Gln Glu Asp Ser Asp His Asp Gly Gln 
    450                 455                 460                 


Gly Asp Ala Cys Asp Asp Asp Asp Asp Asn Asp Gly Val Pro Asp Ser 
465                 470                 475                 480 


Arg Asp Asn Cys Arg Leu Val Pro Asn Pro Gly Gln Glu Asp Ala Asp 
                485                 490                 495     


Arg Asp Gly Val Gly Asp Val Cys Gln Asp Asp Phe Asp Ala Asp Lys 
            500                 505                 510         


Val Val Asp Lys Ile Asp Val Cys Pro Glu Asn Ala Glu Val Thr Leu 
        515                 520                 525             


Thr Asp Phe Arg Ala Phe Gln Thr Val Val Leu Asp Pro Glu Gly Asp 
    530                 535                 540                 


Ala Gln Ile Asp Pro Asn Trp Val Val Leu Asn Gln Gly Arg Glu Ile 
545                 550                 555                 560 


Val Gln Thr Met Asn Ser Asp Pro Gly Leu Ala Val Gly Tyr Thr Ala 
                565                 570                 575     


Phe Asn Gly Val Asp Phe Glu Gly Thr Phe His Val Asn Thr Val Thr 
            580                 585                 590         


Asp Asp Asp Tyr Ala Gly Phe Ile Phe Gly Tyr Gln Asp Ser Ser Ser 
        595                 600                 605             


Phe Tyr Val Val Met Trp Lys Gln Met Glu Gln Thr Tyr Trp Gln Ala 
    610                 615                 620                 


Asn Pro Phe Arg Ala Val Ala Glu Pro Gly Ile Gln Leu Lys Ala Val 
625                 630                 635                 640 


Lys Ser Ser Thr Gly Pro Gly Glu Gln Leu Arg Asn Ala Leu Trp His 
                645                 650                 655     


Thr Gly Asp Thr Glu Ser Gln Val Arg Leu Leu Trp Lys Asp Pro Arg 
            660                 665                 670         


Asn Val Gly Trp Lys Asp Lys Lys Ser Tyr Arg Trp Phe Leu Gln His 
        675                 680                 685             


Arg Pro Gln Val Gly Tyr Ile Arg Val Arg Phe Tyr Glu Gly Pro Glu 
    690                 695                 700                 


Leu Val Ala Asp Ser Asn Val Val Leu Asp Thr Thr Met Arg Gly Gly 
705                 710                 715                 720 


Arg Leu Gly Val Phe Cys Phe Ser Gln Glu Asn Ile Ile Trp Ala Asn 
                725                 730                 735     


Leu Arg Tyr Arg Cys Asn Asp Thr Ile Pro Glu Asp Tyr Glu Thr His 
            740                 745                 750         


Gln Leu Arg Gln Ala 
        755         


<210>  1189
<211>  767
<212>  PRT
<213>  Human

<400>  1189

Met Ser Phe Asp Pro Asn Leu Leu His Asn Asn Gly His Asn Gly Tyr 
1               5                   10                  15      


Pro Asn Gly Thr Ser Ala Ala Leu Arg Glu Thr Gly Val Ile Glu Lys 
            20                  25                  30          


Leu Leu Thr Ser Tyr Gly Phe Ile Gln Cys Ser Glu Arg Gln Ala Arg 
        35                  40                  45              


Leu Phe Phe His Cys Ser Gln Tyr Asn Gly Asn Leu Gln Asp Leu Lys 
    50                  55                  60                  


Val Gly Asp Asp Val Glu Phe Glu Val Ser Ser Asp Arg Arg Thr Gly 
65                  70                  75                  80  


Lys Pro Ile Ala Val Lys Leu Val Lys Ile Lys Gln Glu Ile Leu Pro 
                85                  90                  95      


Glu Glu Arg Met Asn Gly Gln Glu Val Phe Tyr Leu Thr Tyr Thr Pro 
            100                 105                 110         


Glu Asp Val Glu Gly Asn Val Gln Leu Glu Thr Gly Asp Lys Ile Asn 
        115                 120                 125             


Phe Val Ile Asp Asn Asn Lys His Thr Gly Ala Val Ser Ala Arg Asn 
    130                 135                 140                 


Ile Met Leu Leu Lys Lys Lys Gln Ala Arg Cys Gln Gly Val Val Cys 
145                 150                 155                 160 


Ala Met Lys Glu Ala Phe Gly Phe Ile Glu Arg Gly Asp Val Val Lys 
                165                 170                 175     


Glu Ile Phe Phe His Tyr Ser Glu Phe Lys Gly Asp Leu Glu Thr Leu 
            180                 185                 190         


Gln Pro Gly Asp Asp Val Glu Phe Thr Ile Lys Asp Arg Asn Gly Lys 
        195                 200                 205             


Glu Val Ala Thr Asp Val Arg Leu Leu Pro Gln Gly Thr Val Ile Phe 
    210                 215                 220                 


Glu Asp Ile Ser Ile Glu His Phe Glu Gly Thr Val Thr Lys Val Ile 
225                 230                 235                 240 


Pro Lys Val Pro Ser Lys Asn Gln Asn Asp Pro Leu Pro Gly Arg Ile 
                245                 250                 255     


Lys Val Asp Phe Val Ile Pro Lys Glu Leu Pro Phe Gly Asp Lys Asp 
            260                 265                 270         


Thr Lys Ser Lys Val Thr Leu Leu Glu Gly Asp His Val Arg Phe Asn 
        275                 280                 285             


Ile Ser Thr Asp Arg Arg Asp Lys Leu Glu Arg Ala Thr Asn Ile Glu 
    290                 295                 300                 


Val Leu Ser Asn Thr Phe Gln Phe Thr Asn Glu Ala Arg Glu Met Gly 
305                 310                 315                 320 


Val Ile Ala Ala Met Arg Asp Gly Phe Gly Phe Ile Lys Cys Val Asp 
                325                 330                 335     


Arg Asp Val Arg Met Phe Phe His Phe Ser Glu Ile Leu Asp Gly Asn 
            340                 345                 350         


Gln Leu His Ile Ala Asp Glu Val Glu Phe Thr Val Val Pro Asp Met 
        355                 360                 365             


Leu Ser Ala Gln Arg Asn His Ala Ile Arg Ile Lys Lys Leu Pro Lys 
    370                 375                 380                 


Gly Thr Val Ser Phe His Ser His Ser Asp His Arg Phe Leu Gly Thr 
385                 390                 395                 400 


Val Glu Lys Glu Ala Thr Phe Ser Asn Pro Lys Thr Thr Ser Pro Asn 
                405                 410                 415     


Lys Gly Lys Glu Lys Glu Ala Glu Asp Gly Ile Ile Ala Tyr Asp Asp 
            420                 425                 430         


Cys Gly Val Lys Leu Thr Ile Ala Phe Gln Ala Lys Asp Val Glu Gly 
        435                 440                 445             


Ser Thr Ser Pro Gln Ile Gly Asp Lys Val Glu Phe Ser Ile Ser Asp 
    450                 455                 460                 


Lys Gln Arg Pro Gly Gln Gln Val Ala Thr Cys Val Arg Leu Leu Gly 
465                 470                 475                 480 


Arg Asn Ser Asn Ser Lys Arg Leu Leu Gly Tyr Val Ala Thr Leu Lys 
                485                 490                 495     


Asp Asn Phe Gly Phe Ile Glu Thr Ala Asn His Asp Lys Glu Ile Phe 
            500                 505                 510         


Phe His Tyr Ser Glu Phe Ser Gly Asp Val Asp Ser Leu Glu Leu Gly 
        515                 520                 525             


Asp Met Val Glu Tyr Ser Leu Ser Lys Gly Lys Gly Asn Lys Val Ser 
    530                 535                 540                 


Ala Glu Lys Val Asn Lys Thr His Ser Val Asn Gly Ile Thr Glu Glu 
545                 550                 555                 560 


Ala Asp Pro Thr Ile Tyr Ser Gly Lys Val Ile Arg Pro Leu Arg Ser 
                565                 570                 575     


Val Asp Pro Thr Gln Thr Glu Tyr Gln Gly Met Ile Glu Ile Val Glu 
            580                 585                 590         


Glu Gly Asp Met Lys Gly Glu Val Tyr Pro Phe Gly Ile Val Gly Met 
        595                 600                 605             


Ala Asn Lys Gly Asp Cys Leu Gln Lys Gly Glu Ser Val Lys Phe Gln 
    610                 615                 620                 


Leu Cys Val Leu Gly Gln Asn Ala Gln Thr Met Ala Tyr Asn Ile Thr 
625                 630                 635                 640 


Pro Leu Arg Arg Ala Thr Val Glu Cys Val Lys Asp Gln Phe Gly Phe 
                645                 650                 655     


Ile Asn Tyr Glu Val Gly Asp Ser Lys Lys Leu Phe Phe His Val Lys 
            660                 665                 670         


Glu Val Gln Asp Gly Ile Glu Leu Gln Ala Gly Asp Glu Val Glu Phe 
        675                 680                 685             


Ser Val Ile Leu Asn Gln Arg Thr Gly Lys Cys Ser Ala Cys Asn Val 
    690                 695                 700                 


Trp Arg Val Cys Glu Gly Pro Lys Ala Val Ala Ala Pro Arg Pro Asp 
705                 710                 715                 720 


Arg Leu Val Asn Arg Leu Lys Asn Ile Thr Leu Asp Asp Ala Ser Ala 
                725                 730                 735     


Pro Arg Leu Met Val Leu Arg Gln Pro Arg Gly Pro Asp Asn Ser Met 
            740                 745                 750         


Gly Phe Gly Ala Glu Arg Lys Ile Arg Gln Ala Gly Val Ile Asp 
        755                 760                 765         


<210>  1190
<211>  3298
<212>  PRT
<213>  Human

<400>  1190

Met Gln Lys Glu Leu Gly Ile Val Pro Ser Cys Pro Gly Met Lys Ser 
1               5                   10                  15      


Pro Arg Pro His Leu Leu Leu Pro Leu Leu Leu Leu Leu Leu Leu Leu 
            20                  25                  30          


Leu Gly Ala Gly Val Pro Gly Ala Trp Gly Gln Ala Gly Ser Leu Asp 
        35                  40                  45              


Leu Gln Ile Asp Glu Glu Gln Pro Ala Gly Thr Leu Ile Gly Asp Ile 
    50                  55                  60                  


Ser Ala Gly Leu Pro Ala Gly Thr Ala Ala Pro Leu Met Tyr Phe Ile 
65                  70                  75                  80  


Ser Ala Gln Glu Gly Ser Gly Val Gly Thr Asp Leu Ala Ile Asp Glu 
                85                  90                  95      


His Ser Gly Val Val Arg Thr Ala Arg Val Leu Asp Arg Glu Gln Arg 
            100                 105                 110         


Asp Arg Tyr Arg Phe Thr Ala Val Thr Pro Asp Gly Ala Thr Val Glu 
        115                 120                 125             


Val Thr Val Arg Val Ala Asp Ile Asn Asp His Ala Pro Ala Phe Pro 
    130                 135                 140                 


Gln Ala Arg Ala Ala Leu Gln Val Pro Glu His Thr Ala Phe Gly Thr 
145                 150                 155                 160 


Arg Tyr Pro Leu Glu Pro Ala Arg Asp Ala Asp Ala Gly Arg Leu Gly 
                165                 170                 175     


Thr Gln Gly Tyr Ala Leu Ser Gly Asp Gly Ala Gly Glu Thr Phe Arg 
            180                 185                 190         


Leu Glu Thr Arg Pro Gly Pro Asp Gly Thr Pro Val Pro Glu Leu Val 
        195                 200                 205             


Val Thr Gly Glu Leu Asp Arg Glu Asn Arg Ser His Tyr Met Leu Gln 
    210                 215                 220                 


Leu Glu Ala Tyr Asp Gly Gly Ser Pro Pro Arg Arg Ala Gln Ala Leu 
225                 230                 235                 240 


Leu Asp Val Thr Leu Leu Asp Ile Asn Asp His Ala Pro Ala Phe Asn 
                245                 250                 255     


Gln Ser Arg Tyr His Ala Val Val Ser Glu Ser Leu Ala Pro Gly Ser 
            260                 265                 270         


Pro Val Leu Gln Val Phe Ala Ser Asp Ala Asp Ala Gly Val Asn Gly 
        275                 280                 285             


Ala Val Thr Tyr Glu Ile Asn Arg Arg Gln Ser Glu Gly Asp Gly Pro 
    290                 295                 300                 


Phe Ser Ile Asp Ala His Thr Gly Leu Leu Gln Leu Glu Arg Pro Leu 
305                 310                 315                 320 


Asp Phe Glu Gln Arg Arg Val His Glu Leu Val Val Gln Ala Arg Asp 
                325                 330                 335     


Gly Gly Ala His Pro Glu Leu Gly Ser Ala Phe Val Thr Val His Val 
            340                 345                 350         


Arg Asp Ala Asn Asp Asn Gln Pro Ser Met Thr Val Ile Phe Leu Ser 
        355                 360                 365             


Ala Asp Gly Ser Pro Gln Val Ser Glu Ala Ala Pro Pro Gly Gln Leu 
    370                 375                 380                 


Val Ala Arg Ile Ser Val Ser Asp Pro Asp Asp Gly Asp Phe Ala His 
385                 390                 395                 400 


Val Asn Val Ser Leu Glu Gly Gly Glu Gly His Phe Ala Leu Ser Thr 
                405                 410                 415     


Gln Asp Ser Val Ile Tyr Leu Val Cys Val Ala Arg Arg Leu Asp Arg 
            420                 425                 430         


Glu Glu Arg Asp Ala Tyr Asn Leu Arg Val Thr Ala Thr Asp Ser Gly 
        435                 440                 445             


Ser Pro Pro Leu Arg Ala Glu Ala Ala Phe Val Leu His Val Thr Asp 
    450                 455                 460                 


Val Asn Asp Asn Ala Pro Ala Phe Asp Arg Gln Leu Tyr Arg Pro Glu 
465                 470                 475                 480 


Pro Leu Pro Glu Val Ala Leu Pro Gly Ser Phe Val Val Arg Val Thr 
                485                 490                 495     


Ala Arg Asp Pro Asp Gln Gly Thr Asn Gly Gln Val Thr Tyr Ser Leu 
            500                 505                 510         


Ala Pro Gly Ala His Thr His Trp Phe Ser Ile Asp Pro Thr Ser Gly 
        515                 520                 525             


Ile Ile Thr Thr Ala Ala Ser Leu Asp Tyr Glu Leu Glu Pro Gln Pro 
    530                 535                 540                 


Gln Leu Ile Val Val Ala Thr Asp Gly Gly Leu Pro Pro Leu Ala Ser 
545                 550                 555                 560 


Ser Ala Thr Val Ser Val Ala Leu Gln Asp Val Asn Asp Asn Glu Pro 
                565                 570                 575     


Gln Phe Gln Arg Thr Phe Tyr Asn Ala Ser Leu Pro Glu Gly Thr Gln 
            580                 585                 590         


Pro Gly Thr Cys Phe Leu Gln Val Thr Ala Thr Asp Ala Asp Ser Gly 
        595                 600                 605             


Pro Phe Gly Leu Leu Ser Tyr Ser Leu Gly Ala Gly Leu Gly Ser Ser 
    610                 615                 620                 


Gly Ser Pro Pro Phe Arg Ile Asp Ala His Ser Gly Asp Val Cys Thr 
625                 630                 635                 640 


Thr Arg Thr Leu Asp Arg Asp Gln Gly Pro Ser Ser Phe Asp Phe Thr 
                645                 650                 655     


Val Thr Ala Val Asp Gly Gly Gly Leu Lys Ser Met Val Tyr Val Lys 
            660                 665                 670         


Val Phe Leu Ser Asp Glu Asn Asp Asn Pro Pro Gln Phe Tyr Pro Arg 
        675                 680                 685             


Glu Tyr Ala Ala Ser Ile Ser Ala Gln Ser Pro Pro Gly Thr Ala Val 
    690                 695                 700                 


Leu Arg Leu Arg Ala His Asp Pro Asp Gln Gly Ser His Gly Arg Leu 
705                 710                 715                 720 


Ser Tyr His Ile Leu Ala Gly Asn Ser Pro Pro Leu Phe Thr Leu Asp 
                725                 730                 735     


Glu Gln Ser Gly Leu Leu Thr Val Ala Trp Pro Leu Ala Arg Arg Ala 
            740                 745                 750         


Asn Ser Val Val Gln Leu Glu Ile Gly Ala Glu Asp Gly Gly Gly Leu 
        755                 760                 765             


Gln Ala Glu Pro Ser Ala Arg Val Asp Ile Ser Ile Val Pro Gly Thr 
    770                 775                 780                 


Pro Thr Pro Pro Ile Phe Glu Gln Leu Gln Tyr Val Phe Ser Val Pro 
785                 790                 795                 800 


Glu Asp Val Ala Pro Gly Thr Ser Val Gly Ile Val Gln Ala His Asn 
                805                 810                 815     


Pro Pro Gly Arg Leu Ala Pro Val Thr Leu Ser Leu Ser Gly Gly Asp 
            820                 825                 830         


Pro Arg Gly Leu Phe Ser Leu Asp Ala Val Ser Gly Leu Leu Gln Thr 
        835                 840                 845             


Leu Arg Pro Leu Asp Arg Glu Leu Leu Gly Pro Val Leu Glu Leu Glu 
    850                 855                 860                 


Val Arg Ala Gly Ser Gly Val Pro Pro Ala Phe Ala Val Ala Arg Val 
865                 870                 875                 880 


Arg Val Leu Leu Asp Asp Val Asn Asp Asn Ser Pro Ala Phe Pro Ala 
                885                 890                 895     


Pro Glu Asp Thr Val Leu Leu Pro Pro Asn Thr Ala Pro Gly Thr Pro 
            900                 905                 910         


Ile Tyr Thr Leu Arg Ala Leu Asp Pro Asp Ser Gly Val Asn Ser Arg 
        915                 920                 925             


Val Thr Phe Thr Leu Leu Ala Gly Gly Gly Gly Ala Phe Thr Val Asp 
    930                 935                 940                 


Pro Thr Thr Gly His Val Arg Leu Met Arg Pro Leu Gly Pro Ser Gly 
945                 950                 955                 960 


Gly Pro Ala His Glu Leu Glu Leu Glu Ala Arg Asp Gly Gly Ser Pro 
                965                 970                 975     


Pro Arg Thr Ser His Phe Arg Leu Arg Val Val Val Gln Asp Val Gly 
            980                 985                 990         


Thr Arg Gly Leu Ala Pro Arg Phe  Asn Ser Pro Thr Tyr  Arg Val Asp 
        995                 1000                 1005             


Leu Pro  Ser Gly Thr Thr Ala  Gly Thr Gln Val Leu  Gln Val Gln 
    1010                 1015                 1020             


Ala Gln  Ala Pro Asp Gly Gly  Pro Ile Thr Tyr His  Leu Ala Ala 
    1025                 1030                 1035             


Glu Gly  Ala Ser Ser Pro Phe  Gly Leu Glu Pro Gln  Ser Gly Trp 
    1040                 1045                 1050             


Leu Trp  Val Arg Ala Ala Leu  Asp Arg Glu Ala Gln  Glu Leu Tyr 
    1055                 1060                 1065             


Ile Leu  Lys Val Met Ala Val  Ser Gly Ser Lys Ala  Glu Leu Gly 
    1070                 1075                 1080             


Gln Gln  Thr Gly Thr Ala Thr  Val Arg Val Ser Ile  Leu Asn Gln 
    1085                 1090                 1095             


Asn Glu  His Ser Pro Arg Leu  Ser Glu Asp Pro Thr  Phe Leu Ala 
    1100                 1105                 1110             


Val Ala  Glu Asn Gln Pro Pro  Gly Thr Ser Val Gly  Arg Val Phe 
    1115                 1120                 1125             


Ala Thr  Asp Arg Asp Ser Gly  Pro Asn Gly Arg Leu  Thr Tyr Ser 
    1130                 1135                 1140             


Leu Gln  Gln Leu Ser Glu Asp  Ser Lys Ala Phe Arg  Ile His Pro 
    1145                 1150                 1155             


Gln Thr  Gly Glu Val Thr Thr  Leu Gln Thr Leu Asp  Arg Glu Gln 
    1160                 1165                 1170             


Gln Ser  Ser Tyr Gln Leu Leu  Val Gln Val Gln Asp  Gly Gly Ser 
    1175                 1180                 1185             


Pro Pro  Arg Ser Thr Thr Gly  Thr Val His Val Ala  Val Leu Asp 
    1190                 1195                 1200             


Leu Asn  Asp Asn Ser Pro Thr  Phe Leu Gln Ala Ser  Gly Ala Ala 
    1205                 1210                 1215             


Gly Gly  Gly Leu Pro Ile Gln  Val Pro Asp Arg Val  Pro Pro Gly 
    1220                 1225                 1230             


Thr Leu  Val Thr Thr Leu Gln  Ala Lys Asp Pro Asp  Glu Gly Glu 
    1235                 1240                 1245             


Asn Gly  Thr Ile Leu Tyr Thr  Leu Thr Gly Pro Gly  Ser Glu Leu 
    1250                 1255                 1260             


Phe Ser  Leu His Pro His Ser  Gly Glu Leu Leu Thr  Ala Ala Pro 
    1265                 1270                 1275             


Leu Ile  Arg Ala Glu Arg Pro  His Tyr Val Leu Thr  Leu Ser Ala 
    1280                 1285                 1290             


His Asp  Gln Gly Ser Pro Pro  Arg Ser Ala Ser Leu  Gln Leu Leu 
    1295                 1300                 1305             


Val Gln  Val Leu Pro Ser Ala  Arg Leu Ala Glu Pro  Pro Pro Asp 
    1310                 1315                 1320             


Leu Ala  Glu Arg Asp Pro Ala  Ala Pro Val Pro Val  Val Leu Thr 
    1325                 1330                 1335             


Val Thr  Ala Ala Glu Gly Leu  Arg Pro Gly Ser Leu  Leu Gly Ser 
    1340                 1345                 1350             


Val Ala  Ala Pro Glu Pro Ala  Gly Val Gly Ala Leu  Thr Tyr Thr 
    1355                 1360                 1365             


Leu Val  Gly Gly Ala Asp Pro  Glu Gly Thr Phe Ala  Leu Asp Ala 
    1370                 1375                 1380             


Ala Ser  Gly Arg Leu Tyr Leu  Ala Arg Pro Leu Asp  Phe Glu Ala 
    1385                 1390                 1395             


Gly Pro  Pro Trp Arg Ala Leu  Thr Val Arg Ala Glu  Gly Pro Gly 
    1400                 1405                 1410             


Gly Ala  Gly Ala Arg Leu Leu  Arg Val Gln Val Gln  Val Gln Asp 
    1415                 1420                 1425             


Glu Asn  Glu His Ala Pro Ala  Phe Ala Arg Asp Pro  Leu Ala Leu 
    1430                 1435                 1440             


Ala Leu  Pro Glu Asn Pro Glu  Pro Gly Ala Ala Leu  Tyr Thr Phe 
    1445                 1450                 1455             


Arg Ala  Ser Asp Ala Asp Gly  Pro Gly Pro Asn Ser  Asp Val Arg 
    1460                 1465                 1470             


Tyr Arg  Leu Leu Arg Gln Glu  Pro Pro Val Pro Ala  Leu Arg Leu 
    1475                 1480                 1485             


Asp Ala  Arg Thr Gly Ala Leu  Ser Ala Pro Arg Gly  Leu Asp Arg 
    1490                 1495                 1500             


Glu Thr  Thr Pro Ala Leu Leu  Leu Leu Val Glu Ala  Thr Asp Arg 
    1505                 1510                 1515             


Pro Ala  Asn Ala Ser Arg Arg  Arg Ala Ala Arg Val  Ser Ala Arg 
    1520                 1525                 1530             


Val Phe  Val Thr Asp Glu Asn  Asp Asn Ala Pro Val  Phe Ala Ser 
    1535                 1540                 1545             


Pro Ser  Arg Val Arg Leu Pro  Glu Asp Gln Pro Pro  Gly Pro Ala 
    1550                 1555                 1560             


Ala Leu  His Val Val Ala Arg  Asp Pro Asp Leu Gly  Glu Ala Ala 
    1565                 1570                 1575             


Arg Val  Ser Tyr Arg Leu Ala  Ser Gly Gly Asp Gly  His Phe Arg 
    1580                 1585                 1590             


Leu His  Ser Ser Thr Gly Ala  Leu Ser Val Val Arg  Pro Leu Asp 
    1595                 1600                 1605             


Arg Glu  Gln Arg Ala Glu His  Val Leu Thr Val Val  Ala Ser Asp 
    1610                 1615                 1620             


His Gly  Ser Pro Pro Arg Ser  Ala Thr Gln Val Leu  Thr Val Ser 
    1625                 1630                 1635             


Val Ala  Asp Val Asn Asp Glu  Ala Pro Thr Phe Gln  Gln Gln Glu 
    1640                 1645                 1650             


Tyr Ser  Val Leu Leu Arg Glu  Asn Asn Pro Pro Gly  Thr Ser Leu 
    1655                 1660                 1665             


Leu Thr  Leu Arg Ala Thr Asp  Pro Asp Val Gly Ala  Asn Gly Gln 
    1670                 1675                 1680             


Val Thr  Tyr Gly Gly Val Ser  Ser Glu Ser Phe Ser  Leu Asp Pro 
    1685                 1690                 1695             


Asp Thr  Gly Val Leu Thr Thr  Leu Arg Ala Leu Asp  Arg Glu Glu 
    1700                 1705                 1710             


Gln Glu  Glu Ile Asn Leu Thr  Val Tyr Ala Gln Asp  Arg Gly Ser 
    1715                 1720                 1725             


Pro Pro  Gln Leu Thr His Val  Thr Val Arg Val Ala  Val Glu Asp 
    1730                 1735                 1740             


Glu Asn  Asp His Ala Pro Thr  Phe Gly Ser Ala His  Leu Ser Leu 
    1745                 1750                 1755             


Glu Val  Pro Glu Gly Gln Asp  Pro Gln Thr Leu Thr  Met Leu Arg 
    1760                 1765                 1770             


Ala Ser  Asp Pro Asp Val Gly  Ala Asn Gly Gln Leu  Gln Tyr Arg 
    1775                 1780                 1785             


Ile Leu  Asp Gly Asp Pro Ser  Gly Ala Phe Val Leu  Asp Leu Ala 
    1790                 1795                 1800             


Ser Gly  Glu Phe Gly Thr Met  Arg Pro Leu Asp Arg  Glu Val Glu 
    1805                 1810                 1815             


Pro Ala  Phe Gln Leu Arg Ile  Glu Ala Arg Asp Gly  Gly Gln Pro 
    1820                 1825                 1830             


Ala Leu  Ser Ala Thr Leu Leu  Leu Thr Val Thr Val  Leu Asp Ala 
    1835                 1840                 1845             


Asn Asp  His Ala Pro Ala Phe  Pro Val Pro Ala Tyr  Ser Val Glu 
    1850                 1855                 1860             


Val Pro  Glu Asp Val Pro Ala  Gly Thr Leu Leu Leu  Gln Leu Gln 
    1865                 1870                 1875             


Ala His  Asp Pro Asp Ala Gly  Ala Asn Gly His Val  Thr Tyr Tyr 
    1880                 1885                 1890             


Leu Gly  Ala Gly Thr Ala Gly  Ala Phe Leu Leu Glu  Pro Ser Ser 
    1895                 1900                 1905             


Gly Glu  Leu Arg Thr Ala Ala  Ala Leu Asp Arg Glu  Gln Cys Pro 
    1910                 1915                 1920             


Ser Tyr  Thr Phe Ser Val Ser  Ala Val Asp Gly Ala  Ala Ala Gly 
    1925                 1930                 1935             


Pro Leu  Ser Thr Thr Val Ser  Val Thr Ile Thr Val  Arg Asp Val 
    1940                 1945                 1950             


Asn Asp  His Ala Pro Thr Phe  Pro Thr Ser Pro Leu  Arg Leu Arg 
    1955                 1960                 1965             


Leu Pro  Arg Pro Gly Pro Ser  Phe Ser Thr Pro Thr  Leu Ala Leu 
    1970                 1975                 1980             


Ala Thr  Leu Arg Ala Glu Asp  Arg Asp Ala Gly Ala  Asn Ala Ser 
    1985                 1990                 1995             


Ile Leu  Tyr Arg Leu Ala Gly  Thr Pro Pro Pro Gly  Thr Thr Val 
    2000                 2005                 2010             


Asp Ser  Tyr Thr Gly Glu Ile  Arg Val Ala Arg Ser  Pro Val Ala 
    2015                 2020                 2025             


Leu Gly  Pro Arg Asp Arg Val  Leu Phe Ile Val Ala  Thr Asp Leu 
    2030                 2035                 2040             


Gly Arg  Pro Ala Arg Ser Ala  Thr Gly Val Ile Ile  Val Gly Leu 
    2045                 2050                 2055             


Gln Gly  Glu Ala Glu Arg Gly  Pro Arg Phe Pro Arg  Ala Ser Ser 
    2060                 2065                 2070             


Glu Ala  Thr Ile Arg Glu Asn  Ala Pro Pro Gly Thr  Pro Ile Val 
    2075                 2080                 2085             


Ser Pro  Arg Ala Val His Ala  Gly Gly Thr Asn Gly  Pro Ile Thr 
    2090                 2095                 2100             


Tyr Ser  Ile Leu Ser Gly Asn  Glu Lys Gly Thr Phe  Ser Ile Gln 
    2105                 2110                 2115             


Pro Ser  Thr Gly Ala Ile Thr  Val Arg Ser Ala Glu  Gly Leu Asp 
    2120                 2125                 2130             


Phe Glu  Val Ser Pro Arg Leu  Arg Leu Val Leu Gln  Ala Glu Ser 
    2135                 2140                 2145             


Gly Gly  Ala Phe Ala Phe Thr  Val Leu Thr Leu Thr  Leu Gln Asp 
    2150                 2155                 2160             


Ala Asn  Asp Asn Ala Pro Arg  Phe Leu Arg Pro His  Tyr Val Ala 
    2165                 2170                 2175             


Phe Leu  Pro Glu Ser Arg Pro  Leu Glu Gly Pro Leu  Leu Gln Val 
    2180                 2185                 2190             


Glu Ala  Asp Asp Leu Asp Gln  Gly Ser Gly Gly Gln  Ile Ser Tyr 
    2195                 2200                 2205             


Ser Leu  Ala Ala Ser Gln Pro  Ala Arg Gly Leu Phe  His Val Asp 
    2210                 2215                 2220             


Pro Thr  Thr Gly Thr Ile Thr  Thr Thr Ala Ile Leu  Asp Arg Glu 
    2225                 2230                 2235             


Ile Trp  Ala Glu Thr Arg Leu  Val Leu Met Ala Thr  Asp Arg Gly 
    2240                 2245                 2250             


Ser Pro  Ala Leu Val Gly Ser  Ala Thr Leu Thr Val  Met Val Ile 
    2255                 2260                 2265             


Asp Thr  Asn Asp Asn Arg Pro  Thr Ile Pro Gln Pro  Trp Glu Leu 
    2270                 2275                 2280             


Arg Val  Ser Glu Asp Ala Leu  Leu Gly Ser Glu Ile  Ala Gln Val 
    2285                 2290                 2295             


Thr Gly  Asn Asp Val Asp Ser  Gly Pro Val Leu Trp  Tyr Val Leu 
    2300                 2305                 2310             


Ser Pro  Ser Gly Pro Gln Asp  Pro Phe Ser Val Gly  Arg Tyr Gly 
    2315                 2320                 2325             


Gly Arg  Val Ser Leu Thr Gly  Pro Leu Asp Phe Glu  Gln Cys Asp 
    2330                 2335                 2340             


Arg Tyr  Gln Leu Gln Leu Leu  Ala His Asp Gly Pro  His Glu Gly 
    2345                 2350                 2355             


Arg Ala  Asn Leu Thr Val Leu  Val Glu Asp Val Asn  Asp Asn Ala 
    2360                 2365                 2370             


Pro Ala  Phe Ser Gln Ser Leu  Tyr Gln Val Met Leu  Leu Glu His 
    2375                 2380                 2385             


Thr Pro  Pro Gly Ser Ala Ile  Leu Ser Val Ser Ala  Thr Asp Arg 
    2390                 2395                 2400             


Asp Ser  Gly Ala Asn Gly His  Ile Ser Tyr His Leu  Ala Ser Pro 
    2405                 2410                 2415             


Ala Asp  Gly Phe Ser Val Asp  Pro Asn Asn Gly Thr  Leu Phe Thr 
    2420                 2425                 2430             


Ile Val  Gly Thr Val Ala Leu  Gly His Asp Gly Ser  Gly Ala Val 
    2435                 2440                 2445             


Asp Val  Val Leu Glu Ala Arg  Asp His Gly Ala Pro  Gly Arg Ala 
    2450                 2455                 2460             


Ala Arg  Ala Thr Val His Val  Gln Leu Gln Asp Gln  Asn Asp His 
    2465                 2470                 2475             


Ala Pro  Ser Phe Thr Leu Ser  His Tyr Arg Val Ala  Val Thr Glu 
    2480                 2485                 2490             


Asp Leu  Pro Pro Gly Ser Thr  Leu Leu Thr Leu Glu  Ala Thr Asp 
    2495                 2500                 2505             


Ala Asp  Gly Ser Arg Ser His  Ala Ala Val Asp Tyr  Ser Ile Ile 
    2510                 2515                 2520             


Ser Gly  Asn Trp Gly Arg Val  Phe Gln Leu Glu Pro  Arg Leu Ala 
    2525                 2530                 2535             


Glu Ala  Gly Glu Ser Ala Gly  Pro Gly Pro Arg Ala  Leu Gly Cys 
    2540                 2545                 2550             


Leu Val  Leu Leu Glu Pro Leu  Asp Phe Glu Ser Leu  Thr Gln Tyr 
    2555                 2560                 2565             


Asn Leu  Thr Val Ala Ala Ala  Asp Arg Gly Gln Pro  Pro Gln Ser 
    2570                 2575                 2580             


Ser Val  Val Pro Val Thr Val  Thr Val Leu Asp Val  Asn Asp Asn 
    2585                 2590                 2595             


Pro Pro  Val Phe Thr Arg Ala  Ser Tyr Arg Val Thr  Val Pro Glu 
    2600                 2605                 2610             


Asp Thr  Pro Val Gly Ala Glu  Leu Leu His Val Glu  Ala Ser Asp 
    2615                 2620                 2625             


Ala Asp  Pro Gly Pro His Gly  Leu Val Arg Phe Thr  Val Ser Ser 
    2630                 2635                 2640             


Gly Asp  Pro Ser Gly Leu Phe  Glu Leu Asp Glu Ser  Ser Gly Thr 
    2645                 2650                 2655             


Leu Arg  Leu Ala His Ala Leu  Asp Cys Glu Thr Gln  Ala Arg His 
    2660                 2665                 2670             


Gln Leu  Val Val Gln Ala Ala  Asp Pro Ala Gly Ala  His Phe Ala 
    2675                 2680                 2685             


Leu Ala  Pro Val Thr Ile Glu  Val Gln Asp Val Asn  Asp His Gly 
    2690                 2695                 2700             


Pro Ala  Phe Pro Leu Asn Leu  Leu Ser Thr Ser Val  Ala Glu Asn 
    2705                 2710                 2715             


Gln Pro  Pro Gly Thr Leu Val  Thr Thr Leu His Ala  Ile Asp Gly 
    2720                 2725                 2730             


Asp Ala  Gly Ala Phe Gly Arg  Leu Arg Tyr Ser Leu  Leu Glu Ala 
    2735                 2740                 2745             


Gly Pro  Gly Pro Glu Gly Arg  Glu Ala Phe Ala Leu  Asn Ser Ser 
    2750                 2755                 2760             


Thr Gly  Glu Leu Arg Ala Arg  Val Pro Phe Asp Tyr  Glu His Thr 
    2765                 2770                 2775             


Glu Ser  Phe Arg Leu Leu Val  Gly Ala Ala Asp Ala  Gly Asn Leu 
    2780                 2785                 2790             


Ser Ala  Ser Val Thr Val Ser  Val Leu Val Thr Gly  Glu Asp Glu 
    2795                 2800                 2805             


Tyr Asp  Pro Val Phe Leu Ala  Pro Ala Phe His Phe  Gln Val Pro 
    2810                 2815                 2820             


Glu Gly  Ala Arg Arg Gly His  Ser Leu Gly His Val  Gln Ala Thr 
    2825                 2830                 2835             


Asp Glu  Asp Gly Gly Ala Asp  Gly Leu Val Leu Tyr  Ser Leu Ala 
    2840                 2845                 2850             


Thr Ser  Ser Pro Tyr Phe Gly  Ile Asn Gln Thr Thr  Gly Ala Leu 
    2855                 2860                 2865             


Tyr Leu  Arg Val Asp Ser Arg  Ala Pro Gly Ser Gly  Thr Ala Thr 
    2870                 2875                 2880             


Ser Gly  Gly Gly Gly Arg Thr  Arg Arg Glu Ala Pro  Arg Glu Leu 
    2885                 2890                 2895             


Arg Leu  Glu Val Ile Ala Arg  Gly Pro Leu Pro Gly  Ser Arg Ser 
    2900                 2905                 2910             


Ala Thr  Val Pro Val Thr Val  Asp Ile Thr His Thr  Ala Leu Gly 
    2915                 2920                 2925             


Leu Ala  Pro Asp Leu Asn Leu  Leu Leu Val Gly Ala  Val Ala Ala 
    2930                 2935                 2940             


Ser Leu  Gly Val Val Val Val  Leu Ala Leu Ala Ala  Leu Val Leu 
    2945                 2950                 2955             


Gly Leu  Val Arg Ala Arg Ser  Arg Lys Ala Glu Ala  Ala Pro Gly 
    2960                 2965                 2970             


Pro Met  Ser Gln Ala Ala Pro  Leu Ala Ser Asp Ser  Leu Gln Lys 
    2975                 2980                 2985             


Leu Gly  Arg Glu Pro Pro Ser  Pro Pro Pro Ser Glu  His Leu Tyr 
    2990                 2995                 3000             


His Gln  Thr Leu Pro Ser Tyr  Gly Gly Pro Gly Ala  Gly Gly Pro 
    3005                 3010                 3015             


Tyr Pro  Arg Gly Gly Ser Leu  Asp Pro Ser His Ser  Ser Gly Arg 
    3020                 3025                 3030             


Gly Ser  Ala Glu Ala Ala Glu  Asp Asp Glu Ile Arg  Met Ile Asn 
    3035                 3040                 3045             


Glu Phe  Pro Arg Val Ala Ser  Val Ala Ser Ser Leu  Ala Ala Arg 
    3050                 3055                 3060             


Gly Pro  Asp Ser Gly Ile Gln  Gln Asp Ala Asp Gly  Leu Ser Asp 
    3065                 3070                 3075             


Thr Ser  Cys Glu Pro Pro Ala  Pro Asp Thr Trp Tyr  Lys Gly Arg 
    3080                 3085                 3090             


Lys Ala  Gly Leu Leu Leu Pro  Gly Ala Gly Ala Thr  Leu Tyr Arg 
    3095                 3100                 3105             


Glu Glu  Gly Pro Pro Ala Thr  Ala Thr Ala Phe Leu  Gly Gly Cys 
    3110                 3115                 3120             


Gly Leu  Ser Pro Ala Pro Thr  Gly Asp Tyr Gly Phe  Pro Ala Asp 
    3125                 3130                 3135             


Gly Lys  Pro Cys Val Ala Gly  Ala Leu Thr Ala Ile  Val Ala Gly 
    3140                 3145                 3150             


Glu Glu  Glu Leu Arg Gly Ser  Tyr Asn Trp Asp Tyr  Leu Leu Ser 
    3155                 3160                 3165             


Trp Cys  Pro Gln Phe Gln Pro  Leu Ala Ser Val Phe  Thr Glu Ile 
    3170                 3175                 3180             


Ala Arg  Leu Lys Asp Glu Ala  Arg Pro Cys Pro Pro  Ala Pro Arg 
    3185                 3190                 3195             


Ile Asp  Pro Pro Pro Leu Ile  Thr Ala Val Ala His  Pro Gly Ala 
    3200                 3205                 3210             


Lys Ser  Val Pro Pro Lys Pro  Ala Asn Thr Ala Ala  Ala Arg Ala 
    3215                 3220                 3225             


Ile Phe  Pro Pro Ala Ser His  Arg Ser Pro Ile Ser  His Glu Gly 
    3230                 3235                 3240             


Ser Leu  Ser Ser Ala Ala Met  Ser Pro Ser Phe Ser  Pro Ser Leu 
    3245                 3250                 3255             


Ser Pro  Leu Ala Ala Arg Ser  Pro Val Val Ser Pro  Phe Gly Val 
    3260                 3265                 3270             


Ala Gln  Gly Pro Ser Ala Ser  Ala Leu Ser Ala Glu  Ser Gly Leu 
    3275                 3280                 3285             


Glu Pro  Pro Asp Asp Thr Glu  Leu His Ile 
    3290                 3295             


<210>  1191
<211>  1496
<212>  PRT
<213>  Human

<400>  1191

Met Ala Glu Glu Arg Pro Pro Arg Leu Val Asp Tyr Phe Val Val Ala 
1               5                   10                  15      


Gly Leu Ala Gly Asn Gly Ala Pro Ile Pro Glu Glu Thr Trp Val Pro 
            20                  25                  30          


Glu Pro Ser Gly Pro Leu Arg Pro Pro Arg Pro Ala Glu Pro Ile Thr 
        35                  40                  45              


Asp Val Ala Val Ile Ala Arg Ala Leu Gly Glu Glu Val Pro Gln Gly 
    50                  55                  60                  


Tyr Thr Cys Ile Gln Ala Ser Ala Gly Gly His Pro Leu Glu Leu Ser 
65                  70                  75                  80  


Ala Gly Leu Leu Gly Gly Thr Gln Pro Val Ile Cys Tyr Arg Arg Gly 
                85                  90                  95      


Arg Asp Lys Pro Pro Leu Val Glu Leu Gly Val Leu Tyr Glu Gly Lys 
            100                 105                 110         


Glu Arg Pro Lys Pro Gly Phe Gln Val Leu Asp Thr Thr Pro Tyr Ser 
        115                 120                 125             


His Ser Ala Asn Leu Ala Pro Pro Gly Pro Gly His Pro Arg Thr Tyr 
    130                 135                 140                 


Leu Thr Tyr Arg Arg Ala Ala Glu Gly Ala Gly Leu His Ala Leu Gly 
145                 150                 155                 160 


Ile Thr Asp Leu Cys Leu Val Leu Pro Ser Lys Gly Glu Gly Thr Pro 
                165                 170                 175     


His Thr Tyr Cys Arg Leu Pro Arg Asn Leu Asn Pro Gly Met Trp Gly 
            180                 185                 190         


Pro Ala Val Tyr Leu Cys Tyr Lys Val Gly Leu Ala Lys Ala Asn Thr 
        195                 200                 205             


Leu Val Tyr Glu Ala Glu Leu Leu Gly Arg Tyr Pro Glu Glu Asp Asn 
    210                 215                 220                 


Glu Ala Phe Pro Leu Pro Glu Ser Val Pro Val Phe Cys Leu Pro Met 
225                 230                 235                 240 


Gly Ala Thr Ile Glu Cys Trp Pro Ala Gln Thr Lys Tyr Pro Val Pro 
                245                 250                 255     


Val Phe Ser Thr Phe Val Leu Thr Gly Ala Ala Gly Asp Lys Val Tyr 
            260                 265                 270         


Gly Ala Ala Leu Gln Phe Tyr Glu Ala Phe Pro Arg Ala Arg Leu Ser 
        275                 280                 285             


Glu Arg Gln Ala Arg Ala Leu Gly Leu Leu Ser Ala Val Glu Arg Gly 
    290                 295                 300                 


Arg Ala Leu Gly Gly Arg Ala Val Arg Ser Arg Arg Ala Ile Ala Val 
305                 310                 315                 320 


Leu Ser Arg Trp Pro Ala Phe Pro Ala Phe Arg Ala Phe Leu Thr Phe 
                325                 330                 335     


Leu Tyr Arg Tyr Ser Val Ser Gly Pro His Arg Leu Pro Leu Glu Ala 
            340                 345                 350         


His Ile Ser His Phe Ile His Asn Val Pro Phe Pro Ser Pro Gln Arg 
        355                 360                 365             


Pro Arg Ile Leu Val Gln Met Ser Pro Tyr Asp Asn Leu Leu Leu Cys 
    370                 375                 380                 


Gln Pro Val Ser Ser Pro Leu Pro Leu Ser Gly Ala Ser Phe Leu Gln 
385                 390                 395                 400 


Leu Leu Gln Ser Leu Gly Pro Glu Leu Ala Ile Thr Leu Leu Leu Ala 
                405                 410                 415     


Val Leu Thr Glu His Lys Leu Leu Val His Ser Leu Arg Pro Asp Leu 
            420                 425                 430         


Leu Thr Ser Val Cys Glu Ala Leu Val Ser Met Ile Phe Pro Leu His 
        435                 440                 445             


Trp Gln Cys Pro Tyr Ile Pro Leu Cys Pro Leu Val Leu Ala Asp Val 
    450                 455                 460                 


Leu Ser Ala Pro Val Pro Phe Ile Val Gly Ile His Ser Ser Tyr Phe 
465                 470                 475                 480 


Asp Leu His Asp Pro Pro Ala Asp Val Ile Cys Val Asp Leu Asp Thr 
                485                 490                 495     


Asn Thr Leu Phe Gln Thr Glu Glu Lys Lys Leu Leu Ser Pro Arg Thr 
            500                 505                 510         


Leu Pro Arg Arg Pro Tyr Lys Val Leu Leu Ala Thr Leu Thr Asn Leu 
        515                 520                 525             


Tyr Gln Gln Leu Asp Gln Thr Tyr Thr Gly Pro Glu Glu Glu Ala Ser 
    530                 535                 540                 


Leu Glu Phe Leu Leu Thr Asp Tyr Glu Ala Val Cys Gly Arg Arg Ala 
545                 550                 555                 560 


Arg Leu Glu Arg Glu Val Gln Gly Ala Phe Leu Arg Phe Met Ala Cys 
                565                 570                 575     


Leu Leu Lys Gly Tyr Arg Val Phe Leu Arg Pro Leu Thr Gln Ala Pro 
            580                 585                 590         


Ser Glu Gly Ala Arg Asp Val Asp Asn Leu Phe Phe Leu Gln Gly Phe 
        595                 600                 605             


Leu Lys Ser Arg Glu Arg Ser Ser His Lys Leu Tyr Ser Gln Leu Leu 
    610                 615                 620                 


His Thr Gln Met Phe Ser Gln Phe Ile Glu Glu Cys Ser Phe Gly Ser 
625                 630                 635                 640 


Ala Arg His Ala Ala Leu Glu Phe Phe Asp Ser Cys Val Glu Lys Val 
                645                 650                 655     


His Pro Glu Gln Glu Lys Pro Glu Pro Thr Pro Leu Val Glu Leu Glu 
            660                 665                 670         


Glu Leu Ser Gly Ser Glu Leu Thr Val Phe Ile Thr Pro Pro Glu Glu 
        675                 680                 685             


Pro Ala Leu Pro Glu Gly Ser Glu Ser Thr Pro Gln Tyr Cys Tyr Asp 
    690                 695                 700                 


Gly Phe Pro Glu Leu Arg Ala Glu Leu Phe Glu Ser Leu Gln Glu Gln 
705                 710                 715                 720 


Pro Gly Ala Leu Pro Val Pro Gly Pro Ser Arg Ser Ala Pro Ser Ser 
                725                 730                 735     


Pro Ala Pro Arg Arg Thr Lys Gln Glu Met Lys Val Ala Gln Arg Met 
            740                 745                 750         


Ala Gln Lys Ser Ala Ala Val Pro Glu Leu Trp Ala Arg Cys Leu Leu 
        755                 760                 765             


Gly His Cys Tyr Gly Leu Trp Phe Leu Cys Leu Pro Ala Tyr Val Arg 
    770                 775                 780                 


Ser Ala Pro Ser Arg Val Gln Ala Leu His Thr Ala Tyr His Val Leu 
785                 790                 795                 800 


Arg Gln Met Glu Ser Gly Lys Val Val Leu Pro Asp Glu Val Cys Tyr 
                805                 810                 815     


Arg Val Leu Met Gln Leu Cys Ser His Tyr Gly Gln Pro Val Leu Ser 
            820                 825                 830         


Val Arg Val Met Leu Glu Met Arg Gln Ala Gly Ile Val Pro Asn Thr 
        835                 840                 845             


Ile Thr Tyr Gly Tyr Tyr Asn Lys Ala Val Leu Glu Ser Lys Trp Pro 
    850                 855                 860                 


Ser Gly Thr Pro Gly Gly Arg Leu Arg Trp Ala Lys Leu Arg Asn Val 
865                 870                 875                 880 


Val Leu Gly Ala Ala Gln Phe Arg Gln Pro Leu Arg Glu Arg Gln Gln 
                885                 890                 895     


Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Glu Gln 
            900                 905                 910         


Val Ser Ala His Gln Glu Ala Gly Ser Ser Gln Ala Glu Pro Tyr Leu 
        915                 920                 925             


Glu Arg Pro Ser Pro Thr Arg Pro Leu Gln Arg Gln Thr Thr Trp Ala 
    930                 935                 940                 


Gly Arg Ser Leu Arg Asp Pro Ala Ser Pro Pro Gly Arg Leu Val Lys 
945                 950                 955                 960 


Ser Gly Ser Leu Gly Ser Ala Arg Gly Ala Gln Pro Thr Val Glu Ala 
                965                 970                 975     


Gly Val Ala His Met Ile Glu Ala Leu Gly Val Leu Glu Pro Arg Gly 
            980                 985                 990         


Ser Pro Val Pro Trp His Asp Gly  Ser Leu Ser Asp Leu  Ser Leu Thr 
        995                 1000                 1005             


Gly Glu  Glu Pro Leu Pro Gly  Gly Ser Pro Gly Gly  Ser Gly Ser 
    1010                 1015                 1020             


Ala Leu  Ser Ala Gln Ser Thr  Glu Ala Leu Glu Gly  Leu Ser Gly 
    1025                 1030                 1035             


Arg Gly  Pro Lys Ala Gly Gly  Arg Gln Asp Glu Ala  Gly Thr Pro 
    1040                 1045                 1050             


Arg Arg  Gly Leu Gly Ala Arg  Leu Gln Gln Leu Leu  Thr Pro Ser 
    1055                 1060                 1065             


Arg His  Ser Pro Ala Ser Arg  Ile Pro Pro Pro Glu  Leu Pro Pro 
    1070                 1075                 1080             


Asp Leu  Pro Pro Pro Ala Arg  Arg Ser Pro Met Asp  Ser Leu Leu 
    1085                 1090                 1095             


His Pro  Arg Glu Arg Pro Gly  Ser Thr Ala Ser Glu  Ser Ser Ala 
    1100                 1105                 1110             


Ser Leu  Gly Ser Glu Trp Asp  Leu Ser Glu Ser Ser  Leu Ser Asn 
    1115                 1120                 1125             


Leu Ser  Leu Arg Arg Ser Ser  Glu Arg Leu Ser Asp  Thr Pro Gly 
    1130                 1135                 1140             


Ser Phe  Gln Ser Pro Ser Leu  Glu Ile Leu Leu Ser  Ser Cys Ser 
    1145                 1150                 1155             


Leu Cys  Arg Ala Cys Asp Ser  Leu Val Tyr Asp Glu  Glu Ile Met 
    1160                 1165                 1170             


Ala Gly  Trp Ala Pro Asp Asp  Ser Asn Leu Asn Thr  Thr Cys Pro 
    1175                 1180                 1185             


Phe Cys  Ala Cys Pro Phe Val  Pro Leu Leu Ser Val  Gln Thr Leu 
    1190                 1195                 1200             


Asp Ser  Arg Pro Ser Val Pro  Ser Pro Lys Ser Ala  Gly Ala Ser 
    1205                 1210                 1215             


Gly Ser  Lys Asp Ala Pro Val  Pro Gly Gly Pro Gly  Pro Val Leu 
    1220                 1225                 1230             


Ser Asp  Arg Arg Leu Cys Leu  Ala Leu Asp Glu Pro  Gln Leu Cys 
    1235                 1240                 1245             


Asn Gly  His Met Gly Gly Ala  Ser Arg Arg Val Glu  Ser Gly Ala 
    1250                 1255                 1260             


Trp Ala  Tyr Leu Ser Pro Leu  Val Leu Arg Lys Glu  Leu Glu Ser 
    1265                 1270                 1275             


Leu Val  Glu Asn Glu Gly Ser  Glu Val Leu Ala Leu  Pro Glu Leu 
    1280                 1285                 1290             


Pro Ser  Ala His Pro Ile Ile  Phe Trp Asn Leu Leu  Trp Tyr Phe 
    1295                 1300                 1305             


Gln Arg  Leu Arg Leu Pro Ser  Ile Leu Pro Gly Leu  Val Leu Ala 
    1310                 1315                 1320             


Ser Cys  Asp Gly Pro Ser His  Ser Gln Ala Pro Ser  Pro Trp Leu 
    1325                 1330                 1335             


Thr Pro  Asp Pro Ala Ser Val  Gln Val Arg Leu Leu  Trp Asp Val 
    1340                 1345                 1350             


Leu Thr  Pro Asp Pro Asn Ser  Cys Pro Pro Leu Tyr  Val Leu Trp 
    1355                 1360                 1365             


Arg Val  His Ser Gln Ile Pro  Gln Arg Val Val Trp  Pro Gly Pro 
    1370                 1375                 1380             


Val Pro  Ala Ser Leu Ser Leu  Ala Leu Leu Glu Ser  Val Leu Arg 
    1385                 1390                 1395             


His Val  Gly Leu Asn Glu Val  His Lys Ala Val Gly  Leu Leu Leu 
    1400                 1405                 1410             


Glu Thr  Leu Gly Pro Pro Pro  Thr Gly Leu His Leu  Gln Arg Gly 
    1415                 1420                 1425             


Ile Tyr  Arg Glu Ile Leu Phe  Leu Thr Met Ala Ala  Leu Gly Lys 
    1430                 1435                 1440             


Asp His  Val Asp Ile Val Ala  Phe Asp Lys Lys Tyr  Lys Ser Ala 
    1445                 1450                 1455             


Phe Asn  Lys Leu Ala Ser Ser  Met Gly Lys Glu Glu  Leu Arg His 
    1460                 1465                 1470             


Arg Arg  Ala Gln Met Pro Thr  Pro Lys Ala Ile Asp  Cys Arg Lys 
    1475                 1480                 1485             


Cys Phe  Gly Ala Pro Pro Glu  Cys 
    1490                 1495     


<210>  1192
<211>  453
<212>  PRT
<213>  Human

<400>  1192

Met Leu Ser Arg Ser Arg Cys Val Ser Arg Ala Phe Ser Arg Ser Leu 
1               5                   10                  15      


Ser Ala Phe Gln Lys Gly Asn Cys Pro Leu Gly Arg Arg Ser Leu Pro 
            20                  25                  30          


Gly Val Ser Leu Cys Gln Gly Pro Gly Tyr Pro Asn Ser Arg Lys Val 
        35                  40                  45              


Val Ile Asn Asn Ser Val Phe Ser Val Arg Phe Phe Arg Thr Thr Ala 
    50                  55                  60                  


Val Cys Lys Asp Asp Leu Val Thr Val Lys Thr Pro Ala Phe Ala Glu 
65                  70                  75                  80  


Ser Val Thr Glu Gly Asp Val Arg Trp Glu Lys Ala Val Gly Asp Thr 
                85                  90                  95      


Val Ala Glu Asp Glu Val Val Cys Glu Ile Glu Thr Asp Lys Thr Ser 
            100                 105                 110         


Val Gln Val Pro Ser Pro Ala Asn Gly Val Ile Glu Ala Leu Leu Val 
        115                 120                 125             


Pro Asp Gly Gly Lys Val Glu Gly Gly Thr Pro Leu Phe Thr Leu Arg 
    130                 135                 140                 


Lys Thr Gly Ala Ala Pro Ala Lys Ala Lys Pro Ala Glu Ala Pro Ala 
145                 150                 155                 160 


Ala Ala Ala Pro Lys Ala Glu Pro Thr Ala Ala Ala Val Pro Pro Pro 
                165                 170                 175     


Ala Ala Pro Ile Pro Thr Gln Met Pro Pro Val Pro Ser Pro Ser Gln 
            180                 185                 190         


Pro Pro Ser Gly Lys Pro Val Ser Ala Val Lys Pro Thr Val Ala Pro 
        195                 200                 205             


Pro Leu Ala Glu Pro Gly Ala Gly Lys Gly Leu Arg Ser Glu His Arg 
    210                 215                 220                 


Glu Lys Met Asn Arg Met Arg Gln Arg Ile Ala Gln Arg Leu Lys Glu 
225                 230                 235                 240 


Ala Gln Asn Thr Cys Ala Met Leu Thr Thr Phe Asn Glu Ile Asp Met 
                245                 250                 255     


Ser Asn Ile Gln Glu Met Arg Ala Arg His Lys Glu Ala Phe Leu Lys 
            260                 265                 270         


Lys His Asn Leu Lys Leu Gly Phe Met Ser Ala Phe Val Lys Ala Ser 
        275                 280                 285             


Ala Phe Ala Leu Gln Glu Gln Pro Val Val Asn Ala Val Ile Asp Asp 
    290                 295                 300                 


Thr Thr Lys Glu Val Val Tyr Arg Asp Tyr Ile Asp Ile Ser Val Ala 
305                 310                 315                 320 


Val Ala Thr Pro Arg Gly Leu Val Val Pro Val Ile Arg Asn Val Glu 
                325                 330                 335     


Ala Met Asn Phe Ala Asp Ile Glu Arg Thr Ile Thr Glu Leu Gly Glu 
            340                 345                 350         


Lys Ala Arg Lys Asn Glu Leu Ala Ile Glu Asp Met Asp Gly Gly Thr 
        355                 360                 365             


Phe Thr Ile Ser Asn Gly Gly Val Phe Gly Ser Leu Phe Gly Thr Pro 
    370                 375                 380                 


Ile Ile Asn Pro Pro Gln Ser Ala Ile Leu Gly Met His Gly Ile Phe 
385                 390                 395                 400 


Asp Arg Pro Val Ala Ile Gly Gly Lys Val Glu Val Arg Pro Met Met 
                405                 410                 415     


Tyr Val Ala Leu Thr Tyr Asp His Arg Leu Ile Asp Gly Arg Glu Ala 
            420                 425                 430         


Val Thr Phe Leu Arg Lys Ile Lys Ala Ala Val Glu Asp Pro Arg Val 
        435                 440                 445             


Leu Leu Leu Asp Leu 
    450             


<210>  1193
<211>  1537
<212>  PRT
<213>  Human

<400>  1193

Met Gly Glu Lys Leu Glu Leu Arg Leu Lys Ser Pro Val Gly Ala Glu 
1               5                   10                  15      


Pro Ala Val Tyr Pro Trp Pro Leu Pro Val Tyr Asp Lys His His Asp 
            20                  25                  30          


Ala Ala His Glu Ile Ile Glu Thr Ile Arg Trp Val Cys Glu Glu Ile 
        35                  40                  45              


Pro Asp Leu Lys Leu Ala Met Glu Asn Tyr Val Leu Ile Asp Tyr Asp 
    50                  55                  60                  


Thr Lys Ser Phe Glu Ser Met Gln Arg Leu Cys Asp Lys Tyr Asn Arg 
65                  70                  75                  80  


Ala Ile Asp Ser Ile His Gln Leu Trp Lys Gly Thr Thr Gln Pro Met 
                85                  90                  95      


Lys Leu Asn Thr Arg Pro Ser Thr Gly Leu Leu Arg His Ile Leu Gln 
            100                 105                 110         


Gln Val Tyr Asn His Ser Val Thr Asp Pro Glu Lys Leu Asn Asn Tyr 
        115                 120                 125             


Glu Pro Phe Ser Pro Glu Val Tyr Gly Glu Thr Ser Phe Asp Leu Val 
    130                 135                 140                 


Ala Gln Met Ile Asp Glu Ile Lys Met Thr Asp Asp Asp Leu Phe Val 
145                 150                 155                 160 


Asp Leu Gly Ser Gly Val Gly Gln Val Val Leu Gln Val Ala Ala Ala 
                165                 170                 175     


Thr Asn Cys Lys His His Tyr Gly Val Glu Lys Ala Asp Ile Pro Ala 
            180                 185                 190         


Lys Tyr Ala Glu Thr Met Asp Arg Glu Phe Arg Lys Trp Met Lys Trp 
        195                 200                 205             


Tyr Gly Lys Lys His Ala Glu Tyr Thr Leu Glu Arg Gly Asp Phe Leu 
    210                 215                 220                 


Ser Glu Glu Trp Arg Glu Arg Ile Ala Asn Thr Ser Val Ile Phe Val 
225                 230                 235                 240 


Asn Asn Phe Ala Phe Gly Pro Glu Val Asp His Gln Leu Lys Glu Arg 
                245                 250                 255     


Phe Ala Asn Met Lys Glu Gly Gly Arg Ile Val Ser Ser Lys Pro Phe 
            260                 265                 270         


Ala Pro Leu Asn Phe Arg Ile Asn Ser Arg Asn Leu Ser Asp Ile Gly 
        275                 280                 285             


Thr Ile Met Arg Val Val Glu Leu Ser Pro Leu Lys Gly Ser Val Ser 
    290                 295                 300                 


Trp Thr Gly Lys Pro Val Ser Tyr Tyr Leu His Thr Ile Asp Arg Thr 
305                 310                 315                 320 


Ile Leu Glu Asn Tyr Phe Ser Ser Leu Lys Asn Pro Lys Leu Arg Glu 
                325                 330                 335     


Glu Gln Glu Ala Ala Arg Arg Arg Gln Gln Arg Glu Ser Lys Ser Asn 
            340                 345                 350         


Ala Ala Thr Pro Thr Lys Gly Pro Glu Gly Lys Val Ala Gly Pro Ala 
        355                 360                 365             


Asp Ala Pro Met Asp Ser Gly Ala Glu Glu Glu Lys Ala Gly Ala Ala 
    370                 375                 380                 


Thr Val Lys Lys Pro Ser Pro Ser Lys Ala Arg Lys Lys Lys Leu Asn 
385                 390                 395                 400 


Lys Lys Gly Arg Lys Met Ala Gly Arg Lys Arg Gly Arg Pro Lys Lys 
                405                 410                 415     


Met Asn Thr Ala Asn Pro Glu Arg Lys Pro Lys Lys Asn Gln Thr Ala 
            420                 425                 430         


Leu Asp Ala Leu His Ala Gln Thr Val Ser Gln Thr Ala Ala Ser Ser 
        435                 440                 445             


Pro Gln Asp Ala Tyr Arg Ser Pro His Ser Pro Phe Tyr Gln Leu Pro 
    450                 455                 460                 


Pro Ser Val Gln Arg His Ser Pro Asn Pro Leu Leu Val Ala Pro Thr 
465                 470                 475                 480 


Pro Pro Ala Leu Gln Lys Leu Leu Glu Ser Phe Lys Ile Gln Tyr Leu 
                485                 490                 495     


Gln Phe Leu Ala Tyr Thr Lys Thr Pro Gln Tyr Lys Ala Ser Leu Gln 
            500                 505                 510         


Glu Leu Leu Gly Gln Glu Lys Glu Lys Asn Ala Gln Leu Leu Gly Ala 
        515                 520                 525             


Ala Gln Gln Leu Leu Ser His Cys Gln Ala Gln Lys Glu Glu Ile Arg 
    530                 535                 540                 


Arg Leu Phe Gln Gln Lys Leu Asp Glu Leu Gly Val Lys Ala Leu Thr 
545                 550                 555                 560 


Tyr Asn Asp Leu Ile Gln Ala Gln Lys Glu Ile Ser Ala His Asn Gln 
                565                 570                 575     


Gln Leu Arg Glu Gln Ser Glu Gln Leu Glu Gln Asp Asn Arg Ala Leu 
            580                 585                 590         


Arg Gly Gln Ser Leu Gln Leu Leu Lys Ala Arg Cys Glu Glu Leu Gln 
        595                 600                 605             


Leu Asp Trp Ala Thr Leu Ser Leu Glu Lys Leu Leu Lys Glu Lys Gln 
    610                 615                 620                 


Ala Leu Lys Ser Gln Ile Ser Glu Lys Gln Arg His Cys Leu Glu Leu 
625                 630                 635                 640 


Gln Ile Ser Ile Val Glu Leu Glu Lys Ser Gln Arg Gln Gln Glu Leu 
                645                 650                 655     


Leu Gln Leu Lys Ser Cys Val Pro Pro Asp Asp Ala Leu Ser Leu His 
            660                 665                 670         


Leu Arg Gly Lys Gly Ala Leu Gly Arg Glu Leu Glu Pro Asp Ala Ser 
        675                 680                 685             


Arg Leu His Leu Glu Leu Asp Cys Thr Lys Phe Ser Leu Pro His Leu 
    690                 695                 700                 


Ser Ser Met Ser Pro Glu Leu Ser Met Asn Gly Gln Ala Ala Gly Tyr 
705                 710                 715                 720 


Glu Leu Cys Gly Val Leu Ser Arg Pro Ser Ser Lys Gln Asn Thr Pro 
                725                 730                 735     


Gln Tyr Leu Ala Ser Pro Leu Asp Gln Glu Val Val Pro Cys Thr Pro 
            740                 745                 750         


Ser His Val Gly Arg Pro Arg Leu Glu Lys Leu Ser Gly Leu Ala Ala 
        755                 760                 765             


Pro Asp Tyr Thr Arg Leu Ser Pro Ala Lys Ile Val Leu Arg Arg His 
    770                 775                 780                 


Leu Ser Gln Asp His Thr Val Pro Gly Arg Pro Ala Ala Ser Glu Leu 
785                 790                 795                 800 


His Ser Arg Ala Glu His Thr Lys Glu Asn Gly Leu Pro Tyr Gln Ser 
                805                 810                 815     


Pro Ser Val Pro Gly Ser Met Lys Leu Ser Pro Gln Asp Pro Arg Pro 
            820                 825                 830         


Leu Ser Pro Gly Ala Leu Gln Leu Ala Gly Glu Lys Ser Ser Glu Lys 
        835                 840                 845             


Gly Leu Arg Glu Arg Ala Tyr Gly Ser Ser Gly Glu Leu Ile Thr Ser 
    850                 855                 860                 


Leu Pro Ile Ser Ile Pro Leu Ser Thr Val Gln Pro Asn Lys Leu Pro 
865                 870                 875                 880 


Val Ser Ile Pro Leu Ala Ser Val Val Leu Pro Ser Arg Ala Glu Arg 
                885                 890                 895     


Ala Arg Ser Thr Pro Ser Pro Val Leu Gln Pro Arg Asp Pro Ser Ser 
            900                 905                 910         


Thr Leu Glu Lys Gln Ile Gly Ala Asn Ala His Gly Ala Gly Ser Arg 
        915                 920                 925             


Ser Leu Ala Leu Ala Pro Ala Gly Phe Ser Tyr Ala Gly Ser Val Ala 
    930                 935                 940                 


Ile Ser Gly Ala Leu Ala Gly Ser Pro Ala Ser Leu Thr Pro Gly Ala 
945                 950                 955                 960 


Glu Pro Ala Thr Leu Asp Glu Ser Ser Ser Ser Gly Ser Leu Phe Ala 
                965                 970                 975     


Thr Val Gly Ser Arg Ser Ser Thr Pro Gln His Pro Leu Leu Leu Ala 
            980                 985                 990         


Gln Pro Arg Asn Ser Leu Pro Ala  Ser Pro Ala His Gln  Leu Ser Ser 
        995                 1000                 1005             


Ser Pro  Arg Leu Gly Gly Ala  Ala Gln Gly Pro Leu  Pro Glu Ala 
    1010                 1015                 1020             


Ser Lys  Gly Asp Leu Pro Ser  Asp Ser Gly Phe Ser  Asp Pro Glu 
    1025                 1030                 1035             


Ser Glu  Ala Lys Arg Arg Ile  Val Phe Thr Ile Thr  Thr Gly Ala 
    1040                 1045                 1050             


Gly Ser  Ala Lys Gln Ser Pro  Ser Ser Lys His Ser  Pro Leu Thr 
    1055                 1060                 1065             


Ala Ser  Ala Arg Gly Asp Cys  Val Pro Ser His Gly  Gln Asp Ser 
    1070                 1075                 1080             


Arg Arg  Arg Gly Arg Arg Lys  Arg Ala Ser Ala Gly  Thr Pro Ser 
    1085                 1090                 1095             


Leu Ser  Ala Gly Val Ser Pro  Lys Arg Arg Ala Leu  Pro Ser Val 
    1100                 1105                 1110             


Ala Gly  Leu Phe Thr Gln Pro  Ser Gly Ser Pro Leu  Asn Leu Asn 
    1115                 1120                 1125             


Ser Met  Val Ser Asn Ile Asn  Gln Pro Leu Glu Ile  Thr Ala Ile 
    1130                 1135                 1140             


Ser Ser  Pro Glu Thr Ser Leu  Lys Ser Ser Pro Val  Pro Tyr Gln 
    1145                 1150                 1155             


Asp His  Asp Gln Pro Pro Val  Leu Lys Lys Glu Arg  Pro Leu Ser 
    1160                 1165                 1170             


Gln Thr  Asn Gly Ala His Tyr  Ser Pro Leu Thr Ser  Asp Glu Glu 
    1175                 1180                 1185             


Pro Gly  Ser Glu Asp Glu Pro  Ser Ser Ala Arg Ile  Glu Arg Lys 
    1190                 1195                 1200             


Ile Ala  Thr Ile Ser Leu Glu  Ser Lys Ser Pro Pro  Lys Thr Leu 
    1205                 1210                 1215             


Glu Asn  Gly Gly Gly Leu Ala  Gly Arg Lys Pro Ala  Pro Ala Gly 
    1220                 1225                 1230             


Glu Pro  Val Asn Ser Ser Lys  Trp Lys Ser Thr Phe  Ser Pro Ile 
    1235                 1240                 1245             


Ser Asp  Ile Gly Leu Ala Lys  Ser Ala Asp Ser Pro  Leu Gln Ala 
    1250                 1255                 1260             


Ser Ser  Ala Leu Ser Gln Asn  Ser Leu Phe Thr Phe  Arg Pro Ala 
    1265                 1270                 1275             


Leu Glu  Glu Pro Ser Ala Asp  Ala Lys Leu Ala Ala  His Pro Arg 
    1280                 1285                 1290             


Lys Gly  Phe Pro Gly Ser Leu  Ser Gly Ala Asp Gly  Leu Ser Pro 
    1295                 1300                 1305             


Gly Thr  Asn Pro Ala Asn Gly  Cys Thr Phe Gly Gly  Gly Leu Ala 
    1310                 1315                 1320             


Ala Asp  Leu Ser Leu His Ser  Phe Ser Asp Gly Ala  Ser Leu Pro 
    1325                 1330                 1335             


His Lys  Gly Pro Glu Ala Ala  Gly Leu Ser Ser Pro  Leu Ser Phe 
    1340                 1345                 1350             


Pro Ser  Gln Arg Gly Lys Glu  Gly Ser Asp Ala Asn  Pro Phe Leu 
    1355                 1360                 1365             


Ser Lys  Arg Gln Leu Asp Gly  Leu Ala Gly Leu Lys  Gly Glu Gly 
    1370                 1375                 1380             


Ser Arg  Gly Lys Glu Ala Gly  Glu Gly Gly Leu Pro  Leu Cys Gly 
    1385                 1390                 1395             


Pro Thr  Asp Lys Thr Pro Leu  Leu Ser Gly Lys Ala  Ala Lys Ala 
    1400                 1405                 1410             


Arg Asp  Arg Glu Val Asp Leu  Lys Asn Gly His Asn  Leu Phe Ile 
    1415                 1420                 1425             


Ser Ala  Ala Ala Val Pro Pro  Gly Ser Leu Leu Ser  Gly Pro Gly 
    1430                 1435                 1440             


Leu Ala  Pro Ala Ala Ser Ser  Ala Gly Gly Ala Ala  Ser Ser Ala 
    1445                 1450                 1455             


Gln Thr  His Arg Ser Phe Leu  Gly Pro Phe Pro Pro  Gly Pro Gln 
    1460                 1465                 1470             


Phe Ala  Leu Gly Pro Met Ser  Leu Gln Ala Asn Leu  Gly Ser Val 
    1475                 1480                 1485             


Ala Gly  Ser Ser Val Leu Gln  Ser Leu Phe Ser Ser  Val Pro Ala 
    1490                 1495                 1500             


Ala Ala  Gly Leu Val His Val  Ser Ser Ala Ala Thr  Arg Leu Thr 
    1505                 1510                 1515             


Asn Ser  His Ala Met Gly Ser  Phe Ser Gly Val Ala  Gly Gly Thr 
    1520                 1525                 1530             


Val Gly  Gly Asn 
    1535         


<210>  1194
<211>  523
<212>  PRT
<213>  Human

<400>  1194

Met Ala Ala Val Gly Arg Val Gly Ser Phe Gly Ser Ser Pro Pro Gly 
1               5                   10                  15      


Leu Ser Ser Thr Tyr Thr Gly Gly Pro Leu Gly Asn Glu Ile Ala Ser 
            20                  25                  30          


Gly Asn Gly Gly Ala Ala Ala Gly Asp Asp Glu Asp Gly Gln Asn Leu 
        35                  40                  45              


Trp Ser Cys Ile Leu Ser Glu Val Ser Thr Arg Ser Arg Ser Lys Leu 
    50                  55                  60                  


Pro Ala Gly Lys Asn Val Leu Leu Leu Gly Glu Asp Gly Ala Gly Lys 
65                  70                  75                  80  


Thr Ser Leu Ile Arg Lys Ile Gln Gly Ile Glu Glu Tyr Lys Lys Gly 
                85                  90                  95      


Arg Gly Leu Glu Tyr Leu Tyr Leu Asn Val His Asp Glu Asp Arg Asp 
            100                 105                 110         


Asp Gln Thr Arg Cys Asn Val Trp Ile Leu Asp Gly Asp Leu Tyr His 
        115                 120                 125             


Lys Gly Leu Leu Lys Phe Ser Leu Asp Ala Val Ser Leu Lys Asp Thr 
    130                 135                 140                 


Leu Val Met Leu Val Val Asp Met Ser Lys Pro Trp Thr Ala Leu Asp 
145                 150                 155                 160 


Ser Leu Gln Lys Trp Ala Ser Val Val Arg Glu His Val Asp Lys Leu 
                165                 170                 175     


Lys Ile Pro Pro Glu Glu Met Lys Gln Met Glu Gln Lys Leu Ile Arg 
            180                 185                 190         


Asp Phe Gln Glu Tyr Val Glu Pro Gly Glu Asp Phe Pro Ala Ser Pro 
        195                 200                 205             


Gln Arg Arg Asn Thr Ala Ser Gln Glu Asp Lys Asp Asp Ser Val Val 
    210                 215                 220                 


Leu Pro Leu Gly Ala Asp Thr Leu Thr His Asn Leu Gly Ile Pro Val 
225                 230                 235                 240 


Leu Val Val Cys Thr Lys Cys Asp Ala Ile Ser Val Leu Glu Lys Glu 
                245                 250                 255     


His Asp Tyr Arg Asp Glu His Phe Asp Phe Ile Gln Ser His Ile Arg 
            260                 265                 270         


Lys Phe Cys Leu Gln Tyr Gly Ala Ala Leu Ile Tyr Thr Ser Val Lys 
        275                 280                 285             


Glu Asn Lys Asn Ile Asp Leu Val Tyr Lys Tyr Ile Val Gln Lys Leu 
    290                 295                 300                 


Tyr Gly Phe Pro Tyr Lys Ile Pro Ala Val Val Val Glu Lys Asp Ala 
305                 310                 315                 320 


Val Phe Ile Pro Ala Gly Trp Asp Asn Asp Lys Lys Ile Gly Ile Leu 
                325                 330                 335     


His Glu Asn Phe Gln Thr Leu Lys Ala Glu Asp Asn Phe Glu Asp Ile 
            340                 345                 350         


Ile Thr Lys Pro Pro Val Arg Lys Phe Val His Glu Lys Glu Ile Met 
        355                 360                 365             


Ala Glu Asp Asp Gln Val Phe Leu Met Lys Leu Gln Ser Leu Leu Ala 
    370                 375                 380                 


Lys Gln Pro Pro Thr Ala Ala Gly Arg Pro Val Asp Ala Ser Pro Arg 
385                 390                 395                 400 


Val Pro Gly Gly Ser Pro Arg Thr Pro Asn Arg Ser Val Ser Ser Asn 
                405                 410                 415     


Val Ala Ser Val Ser Pro Ile Pro Ala Gly Ser Lys Lys Ile Asp Pro 
            420                 425                 430         


Asn Met Lys Ala Gly Ala Thr Ser Glu Gly Val Leu Ala Asn Phe Phe 
        435                 440                 445             


Asn Ser Leu Leu Ser Lys Lys Thr Gly Ser Pro Gly Gly Pro Gly Val 
    450                 455                 460                 


Ser Gly Gly Ser Pro Ala Gly Gly Ala Gly Gly Gly Ser Ser Gly Leu 
465                 470                 475                 480 


Pro Pro Ser Thr Lys Lys Ser Gly Gln Lys Pro Val Leu Asp Val His 
                485                 490                 495     


Ala Glu Leu Asp Arg Ile Thr Arg Lys Pro Val Thr Val Ser Pro Thr 
            500                 505                 510         


Thr Pro Thr Ser Pro Thr Glu Gly Glu Ala Ser 
        515                 520             


<210>  1195
<211>  314
<212>  PRT
<213>  Human

<400>  1195

Met Leu Val Ser Gly Arg Arg Arg Leu Leu Thr Val Leu Leu Gln Ala 
1               5                   10                  15      


Gln Lys Trp Pro Phe Gln Pro Ser Arg Asp Met Arg Leu Val Gln Phe 
            20                  25                  30          


Arg Ala Pro His Leu Val Gly Pro His Leu Gly Leu Glu Thr Gly Asn 
        35                  40                  45              


Gly Gly Gly Val Ile Asn Leu Asn Ala Phe Asp Pro Thr Leu Pro Lys 
    50                  55                  60                  


Thr Met Thr Gln Phe Leu Glu Gln Gly Glu Ala Thr Leu Ser Val Ala 
65                  70                  75                  80  


Arg Arg Ala Leu Ala Ala Gln Leu Pro Val Leu Pro Arg Ser Glu Val 
                85                  90                  95      


Thr Phe Leu Ala Pro Val Thr Arg Pro Asp Lys Val Val Cys Val Gly 
            100                 105                 110         


Met Asn Tyr Val Asp His Cys Lys Glu Gln Asn Val Pro Val Pro Lys 
        115                 120                 125             


Glu Pro Ile Ile Phe Ser Lys Phe Ala Ser Ser Ile Val Gly Pro Tyr 
    130                 135                 140                 


Asp Glu Val Val Leu Pro Pro Gln Ser Gln Glu Val Asp Trp Glu Val 
145                 150                 155                 160 


Glu Leu Ala Val Val Ile Gly Lys Lys Gly Lys His Ile Lys Ala Thr 
                165                 170                 175     


Asp Ala Met Ala His Val Ala Gly Phe Thr Val Ala His Asp Val Ser 
            180                 185                 190         


Ala Arg Asp Trp Gln Met Arg Arg Asn Gly Lys Gln Trp Leu Leu Gly 
        195                 200                 205             


Lys Thr Phe Asp Thr Phe Cys Pro Leu Gly Pro Ala Leu Val Thr Lys 
    210                 215                 220                 


Asp Ser Val Ala Asp Pro His Asn Leu Lys Ile Cys Cys Arg Val Asn 
225                 230                 235                 240 


Gly Glu Val Val Gln Ser Gly Asn Thr Asn Gln Met Val Phe Lys Thr 
                245                 250                 255     


Glu Asp Leu Ile Ala Trp Val Ser Gln Phe Val Thr Phe Tyr Pro Gly 
            260                 265                 270         


Asp Val Ile Leu Thr Gly Thr Pro Pro Gly Val Gly Val Phe Arg Lys 
        275                 280                 285             


Pro Pro Val Phe Leu Lys Lys Gly Asp Glu Val Gln Cys Glu Ile Glu 
    290                 295                 300                 


Glu Leu Gly Val Ile Ile Asn Lys Val Val 
305                 310                 


<210>  1196
<211>  563
<212>  PRT
<213>  Human

<400>  1196

Met Ser Asp Asp Ala Gly Asp Thr Leu Ala Thr Gly Asp Lys Ala Glu 
1               5                   10                  15      


Val Thr Glu Met Pro Asn Ser Asp Ser Leu Pro Glu Asp Ala Glu Val 
            20                  25                  30          


His Cys Asp Ser Ala Ala Val Ser His Glu Pro Thr Pro Ala Asp Pro 
        35                  40                  45              


Arg Gly Glu Gly His Glu Asn Ala Ala Val Gln Gly Ala Gly Ala Ala 
    50                  55                  60                  


Ala Ile Gly Pro Pro Val Gln Pro Gln Asp Ala Asn Ala Leu Glu Pro 
65                  70                  75                  80  


Pro Leu Asn Arg Asp Val Thr Glu Asp Thr Leu Ala Glu Cys Ile Asp 
                85                  90                  95      


Ser Val Ser Leu Glu Ala Glu Pro Arg Ser Glu Ile Pro Leu Gln Glu 
            100                 105                 110         


Gln Asn Tyr Pro Ala Val Asp Ser Pro Pro Ser Gly Gly Gly Trp Ala 
        115                 120                 125             


Gly Trp Gly Ser Trp Gly Lys Ser Leu Leu Ser Ser Ala Ser Ala Thr 
    130                 135                 140                 


Val Gly His Gly Leu Thr Ala Val Lys Glu Lys Ala Gly Ala Thr Leu 
145                 150                 155                 160 


Arg Ile His Gly Val Asn Ser Gly Ser Ser Glu Gly Ala Gln Pro Asn 
                165                 170                 175     


Thr Glu Asn Gly Val Pro Glu Ile Thr Asp Ala Ala Thr Asp Gln Gly 
            180                 185                 190         


Pro Ala Glu Ser Pro Pro Thr Ser Pro Ser Ser Ala Ser Arg Gly Met 
        195                 200                 205             


Leu Ser Ala Ile Thr Asn Val Val Gln Asn Thr Gly Lys Ser Val Leu 
    210                 215                 220                 


Thr Gly Gly Leu Asp Ala Leu Glu Phe Ile Gly Lys Lys Thr Met Asn 
225                 230                 235                 240 


Val Leu Ala Glu Ser Asp Pro Gly Phe Lys Arg Thr Lys Thr Leu Met 
                245                 250                 255     


Glu Arg Thr Val Ser Leu Ser Gln Met Leu Arg Glu Ala Lys Glu Lys 
            260                 265                 270         


Glu Lys Gln Arg Leu Ala Gln Gln Leu Thr Met Glu Arg Thr Ala His 
        275                 280                 285             


Tyr Gly Met Leu Phe Asp Glu Tyr Gln Gly Leu Ser His Leu Glu Ala 
    290                 295                 300                 


Leu Glu Ile Leu Ser Asn Glu Ser Glu Ser Lys Val Gln Ser Phe Leu 
305                 310                 315                 320 


Ala Ser Leu Asp Gly Glu Lys Leu Glu Leu Leu Lys Asn Asp Leu Ile 
                325                 330                 335     


Ser Ile Lys Asp Ile Phe Ala Ala Lys Glu Leu Glu Asn Glu Glu Asn 
            340                 345                 350         


Gln Glu Glu Gln Gly Leu Glu Glu Lys Gly Glu Glu Phe Ala Arg Met 
        355                 360                 365             


Leu Thr Glu Leu Leu Phe Glu Leu His Val Ala Ala Thr Pro Asp Lys 
    370                 375                 380                 


Leu Asn Lys Ala Met Lys Arg Ala His Asp Trp Val Glu Glu Asp Gln 
385                 390                 395                 400 


Thr Val Val Ser Val Asp Val Ala Lys Val Ser Glu Glu Glu Thr Lys 
                405                 410                 415     


Lys Glu Glu Lys Glu Glu Lys Ser Gln Asp Pro Gln Glu Asp Lys Lys 
            420                 425                 430         


Glu Glu Lys Lys Thr Lys Thr Ile Glu Glu Val Tyr Met Ser Ser Ile 
        435                 440                 445             


Glu Ser Leu Ala Glu Val Thr Ala Arg Cys Ile Glu Gln Leu His Lys 
    450                 455                 460                 


Val Ala Glu Leu Ile Leu His Gly Gln Glu Glu Glu Lys Pro Ala Gln 
465                 470                 475                 480 


Asp Gln Ala Lys Val Leu Ile Lys Leu Thr Thr Ala Met Cys Asn Glu 
                485                 490                 495     


Val Ala Ser Leu Ser Lys Lys Phe Thr Asn Ser Leu Thr Thr Val Gly 
            500                 505                 510         


Ser Asn Lys Lys Ala Glu Val Leu Asn Pro Met Ile Ser Ser Val Leu 
        515                 520                 525             


Leu Glu Gly Cys Asn Ser Thr Thr Tyr Ile Gln Asp Ala Phe Gln Leu 
    530                 535                 540                 


Leu Leu Pro Val Leu Gln Val Ser His Ile Gln Thr Ser Cys Leu Lys 
545                 550                 555                 560 


Ala Gln Pro 
            


<210>  1197
<211>  356
<212>  PRT
<213>  Human

<400>  1197

Met Pro Glu Gly Glu Asp Phe Gly Pro Gly Lys Ser Trp Glu Val Ile 
1               5                   10                  15      


Asn Ser Lys Pro Asp Glu Arg Pro Arg Leu Ser His Cys Ile Ala Glu 
            20                  25                  30          


Ser Trp Met Asn Phe Ser Ile Phe Leu Gln Glu Met Ser Leu Phe Lys 
        35                  40                  45              


Gln Gln Ser Pro Gly Lys Phe Cys Leu Leu Val Cys Ser Val Cys Thr 
    50                  55                  60                  


Phe Phe Thr Ile Leu Gly Ser Tyr Ile Pro Gly Val Ile Leu Ser Tyr 
65                  70                  75                  80  


Leu Leu Leu Leu Cys Ala Phe Leu Cys Pro Leu Phe Lys Cys Asn Asp 
                85                  90                  95      


Ile Gly Gln Lys Ile Tyr Ser Lys Ile Lys Ser Val Leu Leu Lys Leu 
            100                 105                 110         


Asp Phe Gly Ile Gly Glu Tyr Ile Asn Gln Lys Lys Arg Glu Arg Ser 
        115                 120                 125             


Glu Ala Asp Lys Glu Lys Ser His Lys Asp Asp Ser Glu Leu Asp Phe 
    130                 135                 140                 


Ser Ala Leu Cys Pro Lys Ile Ser Leu Thr Val Ala Ala Lys Glu Leu 
145                 150                 155                 160 


Ser Val Ser Asp Thr Asp Val Ser Glu Val Ser Trp Thr Asp Asn Gly 
                165                 170                 175     


Thr Phe Asn Leu Ser Glu Gly Tyr Thr Pro Gln Thr Asp Thr Ser Asp 
            180                 185                 190         


Asp Leu Asp Arg Pro Ser Glu Glu Val Phe Ser Arg Asp Leu Ser Asp 
        195                 200                 205             


Phe Pro Ser Leu Glu Asn Gly Met Gly Thr Asn Asp Glu Asp Glu Leu 
    210                 215                 220                 


Ser Leu Gly Leu Pro Thr Glu Leu Lys Arg Lys Lys Glu Gln Leu Asp 
225                 230                 235                 240 


Ser Gly His Arg Pro Ser Lys Glu Thr Gln Ser Ala Ala Gly Leu Thr 
                245                 250                 255     


Leu Pro Leu Asn Ser Asp Gln Thr Phe His Leu Met Ser Asn Leu Ala 
            260                 265                 270         


Gly Asp Val Ile Thr Ala Ala Val Thr Ala Ala Ile Lys Asp Gln Leu 
        275                 280                 285             


Glu Gly Val Gln Gln Ala Leu Ser Gln Ala Ala Pro Ile Pro Glu Glu 
    290                 295                 300                 


Asp Thr Asp Thr Glu Glu Gly Asp Asp Phe Glu Leu Leu Asp Gln Ser 
305                 310                 315                 320 


Glu Leu Asp Gln Ile Glu Ser Glu Leu Gly Leu Thr Gln Asp Gln Glu 
                325                 330                 335     


Ala Glu Ala Gln Gln Asn Lys Lys Ser Ser Gly Phe Leu Ser Asn Leu 
            340                 345                 350         


Leu Gly Gly His 
        355     


<210>  1198
<211>  393
<212>  PRT
<213>  Human

<400>  1198

Met Ala Asp Arg Arg Arg Arg Leu Arg Pro Gly Thr Leu Ala Pro Val 
1               5                   10                  15      


Arg Glu Gly Val Asn Cys Arg Ser Arg Cys Phe Thr Lys His Lys Asn 
            20                  25                  30          


Gly Leu Lys Phe Pro Thr Ser Leu His Ser Arg Gln Leu Val Phe Pro 
        35                  40                  45              


Arg Lys Gly Leu Asp Asp Phe Arg Lys Gly Cys Pro Pro Cys Thr Gly 
    50                  55                  60                  


Leu Val Thr Gln Val Pro Val Glu Gly Phe Leu Pro Gln Ile Tyr His 
65                  70                  75                  80  


Arg Ala Pro Gln Leu Ala Pro Lys Lys Arg Gln Ile Lys Leu Leu Lys 
                85                  90                  95      


Glu Ala Asp Val Leu Ser Lys Leu Ser Pro Ala Gln Gln Ala Arg Lys 
            100                 105                 110         


Ala Phe Leu Glu Asp Val Glu Ala His Leu Thr Pro His Pro Leu Ala 
        115                 120                 125             


Leu Tyr Leu Asn Leu Glu Glu Ala Met Pro Ile Glu Leu Leu Ser Lys 
    130                 135                 140                 


Val Leu Glu Val Leu Asp Pro Asp Arg Lys Leu Glu Asp Thr Trp Ala 
145                 150                 155                 160 


Tyr Cys Gln Asp Thr Arg Lys Gly Met Lys Glu Pro Thr Lys Leu Leu 
                165                 170                 175     


Lys Lys His Ser Thr Gln Val Tyr Leu Gly Pro Ser Lys Lys Thr Ser 
            180                 185                 190         


Val Ser Asn Ala Gly Gln Trp Leu Tyr Glu Glu Lys Pro His Lys Met 
        195                 200                 205             


Asp Leu Leu His Glu Asn Gly Pro Arg Pro Gly Leu His Glu Asn Gly 
    210                 215                 220                 


Ile Ser Asp Ile Asp Glu Glu Phe Ile Leu Lys Gln Phe Asp Ile Asp 
225                 230                 235                 240 


Tyr Glu Thr Lys Pro Ser His Asp Ala Leu His Thr Met Lys Leu Asn 
                245                 250                 255     


Gln Val Pro Leu Glu Leu Lys Arg Ser Val Gly Leu Ser Lys Leu Gln 
            260                 265                 270         


Glu Thr Glu Phe Phe Gln Lys Leu Gly Tyr Glu Arg Lys Leu Gln Lys 
        275                 280                 285             


Pro Gln Asn Pro Tyr Lys Pro Lys Trp Val Lys Met Arg Tyr Gly Ala 
    290                 295                 300                 


Trp Tyr Leu Asn Pro Lys Leu Trp Lys Lys Gln Arg Val Asp Glu Pro 
305                 310                 315                 320 


Leu Val Asp Pro Glu Val Ser His Lys Ala Gln Glu Glu Asn Phe Lys 
                325                 330                 335     


Lys Glu Leu Gln Glu Gln Glu Glu Leu Leu Ala Asp Leu His Gly Thr 
            340                 345                 350         


Val Ala Phe Lys Asp Phe Ile Leu Ser Arg Gly Tyr Arg Thr Pro Arg 
        355                 360                 365             


Phe Leu Glu Asn Met Tyr Ile Gly Lys Glu Cys Lys Arg Ala Cys Asn 
    370                 375                 380                 


Lys Thr Pro Ile Lys Arg Thr Gln Ala 
385                 390             


<210>  1199
<211>  255
<212>  PRT
<213>  Human

<400>  1199

Met Ala Val Gly Asn Ile Asn Glu Leu Pro Glu Asn Ile Leu Leu Glu 
1               5                   10                  15      


Leu Phe Thr His Val Pro Ala Arg Gln Leu Leu Leu Asn Cys Arg Leu 
            20                  25                  30          


Val Cys Ser Leu Trp Arg Asp Leu Ile Asp Leu Val Thr Leu Trp Lys 
        35                  40                  45              


Arg Lys Cys Leu Arg Glu Gly Phe Ile Thr Glu Asp Trp Asp Gln Pro 
    50                  55                  60                  


Val Ala Asp Trp Lys Ile Phe Tyr Phe Leu Arg Ser Leu His Arg Asn 
65                  70                  75                  80  


Leu Leu His Asn Pro Cys Ala Glu Glu Gly Phe Glu Phe Trp Ser Leu 
                85                  90                  95      


Asp Val Asn Gly Gly Asp Glu Trp Lys Val Glu Asp Leu Ser Arg Asp 
            100                 105                 110         


Gln Arg Lys Glu Phe Pro Asn Asp Gln Val Lys Lys Tyr Phe Val Thr 
        115                 120                 125             


Ser Tyr Tyr Thr Cys Leu Lys Ser Gln Val Val Asp Leu Lys Ala Glu 
    130                 135                 140                 


Gly Tyr Trp Glu Glu Leu Met Asp Thr Thr Arg Pro Asp Ile Glu Val 
145                 150                 155                 160 


Lys Asp Trp Phe Ala Ala Arg Pro Asp Cys Gly Ser Lys Tyr Gln Leu 
                165                 170                 175     


Cys Val Gln Leu Leu Ser Ser Ala His Ala Pro Leu Gly Thr Phe Gln 
            180                 185                 190         


Pro Asp Pro Ala Thr Ile Gln Gln Lys Ser Asp Ala Lys Trp Arg Glu 
        195                 200                 205             


Val Ser His Thr Phe Ser Asn Tyr Pro Pro Gly Val Arg Tyr Ile Trp 
    210                 215                 220                 


Phe Gln His Gly Gly Val Asp Thr His Tyr Trp Ala Gly Trp Tyr Gly 
225                 230                 235                 240 


Pro Arg Val Thr Asn Ser Ser Ile Thr Ile Gly Pro Pro Leu Pro 
                245                 250                 255 


<210>  1200
<211>  582
<212>  PRT
<213>  Human

<400>  1200

Met Phe Pro Ala Gly Pro Pro Ser His Ser Leu Leu Arg Leu Pro Leu 
1               5                   10                  15      


Leu Gln Leu Leu Leu Leu Val Val Gln Ala Val Gly Arg Gly Leu Gly 
            20                  25                  30          


Arg Ala Ser Pro Ala Gly Gly Pro Leu Glu Asp Val Val Ile Glu Arg 
        35                  40                  45              


Tyr His Ile Pro Arg Ala Cys Pro Arg Glu Val Gln Met Gly Asp Phe 
    50                  55                  60                  


Val Arg Tyr His Tyr Asn Gly Thr Phe Glu Asp Gly Lys Lys Phe Asp 
65                  70                  75                  80  


Ser Ser Tyr Asp Arg Asn Thr Leu Val Ala Ile Val Val Gly Val Gly 
                85                  90                  95      


Arg Leu Ile Thr Gly Met Asp Arg Gly Leu Met Gly Met Cys Val Asn 
            100                 105                 110         


Glu Arg Arg Arg Leu Ile Val Pro Pro His Leu Gly Tyr Gly Ser Ile 
        115                 120                 125             


Gly Leu Ala Gly Leu Ile Pro Pro Asp Ala Thr Leu Tyr Phe Asp Val 
    130                 135                 140                 


Val Leu Leu Asp Val Trp Asn Lys Glu Asp Thr Val Gln Val Ser Thr 
145                 150                 155                 160 


Leu Leu Arg Pro Pro His Cys Pro Arg Met Val Gln Asp Gly Asp Phe 
                165                 170                 175     


Val Arg Tyr His Tyr Asn Gly Thr Leu Leu Asp Gly Thr Ser Phe Asp 
            180                 185                 190         


Thr Ser Tyr Ser Lys Gly Gly Thr Tyr Asp Thr Tyr Val Gly Ser Gly 
        195                 200                 205             


Trp Leu Ile Lys Gly Met Asp Gln Gly Leu Leu Gly Met Cys Pro Gly 
    210                 215                 220                 


Glu Arg Arg Lys Ile Ile Ile Pro Pro Phe Leu Ala Tyr Gly Glu Lys 
225                 230                 235                 240 


Gly Tyr Gly Thr Val Ile Pro Pro Gln Ala Ser Leu Val Phe His Val 
                245                 250                 255     


Leu Leu Ile Asp Val His Asn Pro Lys Asp Ala Val Gln Leu Glu Thr 
            260                 265                 270         


Leu Glu Leu Pro Pro Gly Cys Val Arg Arg Ala Gly Ala Gly Asp Phe 
        275                 280                 285             


Met Arg Tyr His Tyr Asn Gly Ser Leu Met Asp Gly Thr Leu Phe Asp 
    290                 295                 300                 


Ser Ser Tyr Ser Arg Asn His Thr Tyr Asn Thr Tyr Ile Gly Gln Gly 
305                 310                 315                 320 


Tyr Ile Ile Pro Gly Met Asp Gln Gly Leu Gln Gly Ala Cys Met Gly 
                325                 330                 335     


Glu Arg Arg Arg Ile Thr Ile Pro Pro His Leu Ala Tyr Gly Glu Asn 
            340                 345                 350         


Gly Thr Gly Asp Lys Ile Pro Gly Ser Ala Val Leu Ile Phe Asn Val 
        355                 360                 365             


His Val Ile Asp Phe His Asn Pro Ala Asp Val Val Glu Ile Arg Thr 
    370                 375                 380                 


Leu Ser Arg Pro Ser Glu Thr Cys Asn Glu Thr Thr Lys Leu Gly Asp 
385                 390                 395                 400 


Phe Val Arg Tyr His Tyr Asn Cys Ser Leu Leu Asp Gly Thr Gln Leu 
                405                 410                 415     


Phe Thr Ser His Asp Tyr Gly Ala Pro Gln Glu Ala Thr Leu Gly Ala 
            420                 425                 430         


Asn Lys Val Ile Glu Gly Leu Asp Thr Gly Leu Gln Gly Met Cys Val 
        435                 440                 445             


Gly Glu Arg Arg Gln Leu Ile Val Pro Pro His Leu Ala His Gly Glu 
    450                 455                 460                 


Ser Gly Ala Arg Gly Val Pro Gly Ser Ala Val Leu Leu Phe Glu Val 
465                 470                 475                 480 


Glu Leu Val Ser Arg Glu Asp Gly Leu Pro Thr Gly Tyr Leu Phe Val 
                485                 490                 495     


Trp His Lys Asp Pro Pro Ala Asn Leu Phe Glu Asp Met Asp Leu Asn 
            500                 505                 510         


Lys Asp Gly Glu Val Pro Pro Glu Glu Phe Ser Thr Phe Ile Lys Ala 
        515                 520                 525             


Gln Val Ser Glu Gly Lys Gly Arg Leu Met Pro Gly Gln Asp Pro Glu 
    530                 535                 540                 


Lys Thr Ile Gly Asp Met Phe Gln Asn Gln Asp Arg Asn Gln Asp Gly 
545                 550                 555                 560 


Lys Ile Thr Val Asp Glu Leu Lys Leu Lys Ser Asp Glu Asp Glu Glu 
                565                 570                 575     


Arg Val His Glu Glu Leu 
            580         


<210>  1201
<211>  1017
<212>  PRT
<213>  Human

<400>  1201

Met Gly Lys Lys Ser Arg Ala Val Pro Gly Arg Arg Pro Ile Leu Gln 
1               5                   10                  15      


Leu Ser Pro Pro Gly Pro Arg Gly Ser Thr Pro Gly Arg Asp Pro Glu 
            20                  25                  30          


Pro Glu Pro Asp Thr Glu Pro Asp Ser Thr Ala Ala Val Pro Ser Gln 
        35                  40                  45              


Pro Ala Pro Ser Ala Ala Thr Thr Thr Thr Thr Ala Val Thr Ala Ala 
    50                  55                  60                  


Ala Ala Ser Asp Asp Ser Pro Ser Glu Asp Glu Gln Glu Ala Val Gln 
65                  70                  75                  80  


Glu Val Pro Arg Val Val Gln Asn Pro Pro Lys Pro Val Met Thr Thr 
                85                  90                  95      


Arg Pro Thr Ala Val Lys Ala Thr Gly Gly Leu Cys Leu Leu Gly Ala 
            100                 105                 110         


Tyr Ala Asp Ser Asp Asp Asp Asp Asn Asp Val Ser Glu Lys Leu Ala 
        115                 120                 125             


Gln Ser Lys Glu Thr Asn Gly Asn Gln Ser Thr Asp Ile Asp Ser Thr 
    130                 135                 140                 


Leu Ala Asn Phe Leu Ala Glu Ile Asp Ala Ile Thr Ala Pro Gln Pro 
145                 150                 155                 160 


Ala Ala Pro Val Gly Ala Ser Ala Pro Pro Pro Thr Pro Pro Arg Pro 
                165                 170                 175     


Glu Pro Lys Glu Ala Ala Thr Ser Thr Leu Ser Ser Ser Thr Ser Asn 
            180                 185                 190         


Gly Thr Asp Ser Thr Gln Thr Ser Gly Trp Gln Tyr Asp Thr Gln Cys 
        195                 200                 205             


Ser Leu Ala Gly Val Gly Ile Glu Met Gly Asp Trp Gln Glu Val Trp 
    210                 215                 220                 


Asp Glu Asn Thr Gly Cys Tyr Tyr Tyr Trp Asn Thr Gln Thr Asn Glu 
225                 230                 235                 240 


Val Thr Trp Glu Leu Pro Gln Tyr Leu Ala Thr Gln Val Gln Gly Leu 
                245                 250                 255     


Gln His Tyr Gln Pro Ser Ser Val Pro Gly Ala Glu Thr Ser Phe Val 
            260                 265                 270         


Val Asn Thr Asp Ile Tyr Ser Lys Glu Lys Thr Ile Ser Val Ser Ser 
        275                 280                 285             


Ser Lys Ser Gly Pro Val Ile Ala Lys Arg Glu Val Lys Lys Glu Val 
    290                 295                 300                 


Asn Glu Gly Ile Gln Ala Leu Ser Asn Ser Glu Glu Glu Lys Lys Gly 
305                 310                 315                 320 


Val Ala Ala Ser Leu Leu Ala Pro Leu Leu Pro Glu Gly Ile Lys Glu 
                325                 330                 335     


Glu Glu Glu Arg Trp Arg Arg Lys Val Ile Cys Lys Glu Glu Pro Val 
            340                 345                 350         


Ser Glu Val Lys Glu Thr Ser Thr Thr Val Glu Glu Ala Thr Thr Ile 
        355                 360                 365             


Val Lys Pro Gln Glu Ile Met Leu Asp Asn Ile Glu Asp Pro Ser Gln 
    370                 375                 380                 


Glu Asp Leu Cys Ser Val Val Gln Ser Gly Glu Ser Glu Glu Glu Glu 
385                 390                 395                 400 


Glu Gln Asp Thr Leu Glu Leu Glu Leu Val Leu Glu Arg Lys Lys Ala 
                405                 410                 415     


Glu Leu Arg Ala Leu Glu Glu Gly Asp Gly Ser Val Ser Gly Ser Ser 
            420                 425                 430         


Pro Arg Ser Asp Ile Ser Gln Pro Ala Ser Gln Asp Gly Met Arg Arg 
        435                 440                 445             


Leu Met Ser Lys Arg Gly Lys Trp Lys Met Phe Val Arg Ala Thr Ser 
    450                 455                 460                 


Pro Glu Ser Thr Ser Arg Ser Ser Ser Lys Thr Gly Arg Asp Thr Pro 
465                 470                 475                 480 


Glu Asn Gly Glu Thr Ala Ile Gly Ala Glu Asn Ser Glu Lys Ile Asp 
                485                 490                 495     


Glu Asn Ser Asp Lys Glu Met Glu Val Glu Glu Ser Pro Glu Lys Ile 
            500                 505                 510         


Lys Val Gln Thr Thr Pro Lys Val Glu Glu Glu Gln Asp Leu Lys Phe 
        515                 520                 525             


Gln Ile Gly Glu Leu Ala Asn Thr Leu Thr Ser Lys Phe Glu Phe Leu 
    530                 535                 540                 


Gly Ile Asn Arg Gln Ser Ile Ser Asn Phe His Val Leu Leu Leu Gln 
545                 550                 555                 560 


Thr Glu Thr Arg Ile Ala Asp Trp Arg Glu Gly Ala Leu Asn Gly Asn 
                565                 570                 575     


Tyr Leu Lys Arg Lys Leu Gln Asp Ala Ala Glu Gln Leu Lys Gln Tyr 
            580                 585                 590         


Glu Ile Asn Ala Thr Pro Lys Gly Trp Ser Cys His Trp Asp Arg Asp 
        595                 600                 605             


His Arg Arg Tyr Phe Tyr Val Asn Glu Gln Ser Gly Glu Ser Gln Trp 
    610                 615                 620                 


Glu Phe Pro Asp Gly Glu Glu Glu Glu Glu Glu Ser Gln Ala Gln Glu 
625                 630                 635                 640 


Asn Arg Asp Glu Thr Leu Ala Lys Gln Thr Leu Lys Asp Lys Thr Gly 
                645                 650                 655     


Thr Asp Ser Asn Ser Thr Glu Ser Ser Glu Thr Ser Thr Gly Ser Leu 
            660                 665                 670         


Cys Lys Glu Ser Phe Ser Gly Gln Val Ser Ser Ser Ser Leu Met Pro 
        675                 680                 685             


Leu Thr Pro Phe Trp Thr Leu Leu Gln Ser Asn Val Pro Val Leu Gln 
    690                 695                 700                 


Pro Pro Leu Pro Leu Glu Met Pro Pro Pro Pro Pro Pro Pro Pro Glu 
705                 710                 715                 720 


Ser Pro Pro Pro Pro Pro Pro Pro Pro Pro Pro Ala Glu Asp Gly Glu 
                725                 730                 735     


Ile Gln Glu Val Glu Met Glu Asp Glu Gly Ser Glu Glu Pro Pro Ala 
            740                 745                 750         


Pro Gly Thr Glu Glu Asp Thr Pro Leu Lys Pro Ser Ala Gln Thr Thr 
        755                 760                 765             


Val Val Thr Ser Gln Ser Ser Val Asp Ser Thr Ile Ser Ser Ser Ser 
    770                 775                 780                 


Ser Thr Lys Gly Ile Lys Arg Lys Ala Thr Glu Ile Ser Thr Ala Val 
785                 790                 795                 800 


Val Gln Arg Ser Ala Thr Ile Gly Ser Ser Pro Val Leu Tyr Ser Gln 
                805                 810                 815     


Ser Ala Ile Ala Thr Gly His Gln Ala Ala Gly Ile Gly Asn Gln Ala 
            820                 825                 830         


Thr Gly Ile Gly His Gln Thr Ile Pro Val Ser Leu Pro Ala Ala Gly 
        835                 840                 845             


Met Gly His Gln Ala Arg Gly Met Ser Leu Gln Ser Asn Tyr Leu Gly 
    850                 855                 860                 


Leu Ala Ala Ala Pro Ala Ile Met Ser Tyr Ala Glu Cys Ser Val Pro 
865                 870                 875                 880 


Ile Gly Val Thr Ala Pro Ser Leu Gln Pro Val Gln Ala Arg Gly Ala 
                885                 890                 895     


Val Pro Thr Ala Thr Ile Ile Glu Pro Pro Pro Pro Pro Pro Pro Pro 
            900                 905                 910         


Pro Pro Pro Pro Pro Pro Ala Pro Lys Met Pro Pro Pro Glu Lys Thr 
        915                 920                 925             


Lys Lys Gly Arg Lys Asp Lys Ala Lys Lys Ser Lys Thr Lys Met Pro 
    930                 935                 940                 


Ser Leu Val Lys Lys Trp Gln Ser Ile Gln Arg Glu Leu Asp Glu Glu 
945                 950                 955                 960 


Asp Asn Ser Ser Ser Ser Glu Glu Asp Arg Glu Ser Thr Ala Gln Lys 
                965                 970                 975     


Arg Ile Glu Glu Trp Lys Gln Gln Gln Leu Val Ser Gly Met Ala Glu 
            980                 985                 990         


Arg Asn Ala Asn Phe Glu Ala Leu  Pro Glu Asp Trp Arg  Ala Arg Leu 
        995                 1000                 1005             


Lys Arg  Arg Lys Met Ala Pro  Asn Thr 
    1010                 1015         


<210>  1202
<211>  345
<212>  PRT
<213>  Human

<400>  1202

Met Ser His Leu Phe Asp Pro Arg Leu Pro Ala Leu Ala Ala Ser Pro 
1               5                   10                  15      


Met Leu Tyr Leu Tyr Gly Pro Glu Arg Pro Gly Leu Pro Leu Ala Phe 
            20                  25                  30          


Ala Pro Ala Ala Ala Leu Ala Ala Ser Gly Arg Ala Glu Thr Pro Gln 
        35                  40                  45              


Lys Pro Pro Tyr Ser Tyr Ile Ala Leu Ile Ala Met Ala Ile Gln Asp 
    50                  55                  60                  


Ala Pro Glu Gln Arg Val Thr Leu Asn Gly Ile Tyr Gln Phe Ile Met 
65                  70                  75                  80  


Asp Arg Phe Pro Phe Tyr His Asp Asn Arg Gln Gly Trp Gln Asn Ser 
                85                  90                  95      


Ile Arg His Asn Leu Ser Leu Asn Asp Cys Phe Val Lys Val Pro Arg 
            100                 105                 110         


Glu Lys Gly Arg Pro Gly Lys Gly Ser Tyr Trp Thr Leu Asp Pro Arg 
        115                 120                 125             


Cys Leu Asp Met Phe Glu Asn Gly Asn Tyr Arg Arg Arg Lys Arg Lys 
    130                 135                 140                 


Pro Lys Pro Gly Pro Gly Ala Pro Glu Ala Lys Arg Pro Arg Ala Glu 
145                 150                 155                 160 


Thr His Gln Arg Ser Ala Glu Ala Gln Pro Glu Ala Gly Ser Gly Ala 
                165                 170                 175     


Gly Gly Ser Gly Pro Ala Ile Ser Arg Leu Gln Ala Ala Pro Ala Gly 
            180                 185                 190         


Pro Ser Pro Leu Leu Asp Gly Pro Ser Pro Pro Ala Pro Leu His Trp 
        195                 200                 205             


Pro Gly Thr Ala Ser Pro Asn Glu Asp Ala Gly Asp Ala Ala Gln Gly 
    210                 215                 220                 


Ala Ala Ala Val Ala Val Gly Gln Ala Ala Arg Thr Gly Asp Gly Pro 
225                 230                 235                 240 


Gly Ser Pro Leu Arg Pro Ala Ser Arg Ser Ser Pro Lys Ser Ser Asp 
                245                 250                 255     


Lys Ser Lys Ser Phe Ser Ile Asp Ser Ile Leu Ala Gly Lys Gln Gly 
            260                 265                 270         


Gln Lys Pro Pro Ser Gly Asp Glu Leu Leu Gly Gly Ala Lys Pro Gly 
        275                 280                 285             


Pro Gly Gly Arg Leu Gly Ala Ser Leu Leu Ala Ala Ser Ser Ser Leu 
    290                 295                 300                 


Arg Pro Pro Phe Asn Ala Ser Leu Met Leu Asp Pro His Val Gln Gly 
305                 310                 315                 320 


Gly Phe Tyr Gln Leu Gly Ile Pro Phe Leu Ser Tyr Phe Pro Leu Gln 
                325                 330                 335     


Val Pro Asp Thr Val Leu His Phe Gln 
            340                 345 


<210>  1203
<211>  440
<212>  PRT
<213>  Human

<400>  1203

Met Gly Leu Gly Val Ser Ala Glu Gln Pro Ala Gly Gly Ala Glu Gly 
1               5                   10                  15      


Phe His Leu His Gly Val Gln Glu Asn Ser Pro Ala Gln Gln Ala Gly 
            20                  25                  30          


Leu Glu Pro Tyr Phe Asp Phe Ile Ile Thr Ile Gly His Ser Arg Leu 
        35                  40                  45              


Asn Lys Glu Asn Asp Thr Leu Lys Ala Leu Leu Lys Ala Asn Val Glu 
    50                  55                  60                  


Lys Pro Val Lys Leu Glu Val Phe Asn Met Lys Thr Met Arg Val Arg 
65                  70                  75                  80  


Glu Val Glu Val Val Pro Ser Asn Met Trp Gly Gly Gln Gly Leu Leu 
                85                  90                  95      


Gly Ala Ser Val Arg Phe Cys Ser Phe Arg Arg Ala Ser Glu Gln Val 
            100                 105                 110         


Trp His Val Leu Asp Val Glu Pro Ser Ser Pro Ala Ala Leu Ala Gly 
        115                 120                 125             


Leu Arg Pro Tyr Thr Asp Tyr Val Val Gly Ser Asp Gln Ile Leu Gln 
    130                 135                 140                 


Glu Ser Glu Asp Phe Phe Thr Leu Ile Glu Ser His Glu Gly Lys Pro 
145                 150                 155                 160 


Leu Lys Leu Met Val Tyr Asn Ser Lys Ser Asp Ser Cys Arg Glu Val 
                165                 170                 175     


Thr Val Thr Pro Asn Ala Ala Trp Gly Gly Glu Gly Ser Leu Gly Cys 
            180                 185                 190         


Gly Ile Gly Tyr Gly Tyr Leu His Arg Ile Pro Thr Gln Pro Pro Ser 
        195                 200                 205             


Tyr His Lys Lys Pro Pro Gly Thr Pro Pro Pro Ser Ala Leu Pro Leu 
    210                 215                 220                 


Gly Ala Pro Pro Pro Asp Ala Leu Pro Pro Gly Pro Thr Pro Glu Asp 
225                 230                 235                 240 


Ser Pro Ser Leu Glu Thr Gly Ser Arg Gln Ser Asp Tyr Met Glu Ala 
                245                 250                 255     


Leu Leu Gln Ala Pro Gly Ser Ser Met Glu Asp Pro Leu Pro Gly Pro 
            260                 265                 270         


Gly Ser Pro Ser His Ser Ala Pro Asp Pro Asp Gly Leu Pro His Phe 
        275                 280                 285             


Met Glu Thr Pro Leu Gln Pro Pro Pro Pro Val Gln Arg Val Met Asp 
    290                 295                 300                 


Pro Gly Phe Leu Asp Val Ser Gly Ile Ser Leu Leu Asp Asn Ser Asn 
305                 310                 315                 320 


Ala Ser Val Trp Pro Ser Leu Pro Ser Ser Thr Glu Leu Thr Thr Thr 
                325                 330                 335     


Ala Val Ser Thr Ser Gly Pro Glu Asp Ile Cys Ser Ser Ser Ser Ser 
            340                 345                 350         


His Glu Arg Gly Gly Glu Ala Thr Trp Ser Gly Ser Glu Phe Glu Val 
        355                 360                 365             


Ser Phe Leu Asp Ser Pro Gly Ala Gln Ala Gln Ala Asp His Leu Pro 
    370                 375                 380                 


Gln Leu Thr Leu Pro Asp Ser Leu Thr Ser Ala Ala Ser Pro Glu Asp 
385                 390                 395                 400 


Gly Leu Ser Ala Glu Leu Leu Glu Ala Gln Ala Glu Glu Glu Pro Ala 
                405                 410                 415     


Ser Thr Glu Gly Leu Asp Thr Gly Thr Glu Ala Glu Gly Leu Asp Ser 
            420                 425                 430         


Gln Ala Gln Ile Ser Thr Thr Glu 
        435                 440 


<210>  1204
<211>  731
<212>  PRT
<213>  Human

<400>  1204

Met Val Val Glu His Pro Glu Phe Leu Lys Ala Gly Lys Glu Pro Gly 
1               5                   10                  15      


Leu Gln Ile Trp Arg Val Glu Lys Phe Asp Leu Val Pro Val Pro Thr 
            20                  25                  30          


Asn Leu Tyr Gly Asp Phe Phe Thr Gly Asp Ala Tyr Val Ile Leu Lys 
        35                  40                  45              


Thr Val Gln Leu Arg Asn Gly Asn Leu Gln Tyr Asp Leu His Tyr Trp 
    50                  55                  60                  


Leu Gly Asn Glu Cys Ser Gln Asp Glu Ser Gly Ala Ala Ala Ile Phe 
65                  70                  75                  80  


Thr Val Gln Leu Asp Asp Tyr Leu Asn Gly Arg Ala Val Gln His Arg 
                85                  90                  95      


Glu Val Gln Gly Phe Glu Ser Ala Thr Phe Leu Gly Tyr Phe Lys Ser 
            100                 105                 110         


Gly Leu Lys Tyr Lys Lys Gly Gly Val Ala Ser Gly Phe Lys His Val 
        115                 120                 125             


Val Pro Asn Glu Val Val Val Gln Arg Leu Phe Gln Val Lys Gly Arg 
    130                 135                 140                 


Arg Val Val Arg Ala Thr Glu Val Pro Val Ser Trp Glu Ser Phe Asn 
145                 150                 155                 160 


Asn Gly Asp Cys Phe Ile Leu Asp Leu Gly Asn Asn Ile His Gln Trp 
                165                 170                 175     


Cys Gly Ser Asn Ser Asn Arg Tyr Glu Arg Leu Lys Ala Thr Gln Val 
            180                 185                 190         


Ser Lys Gly Ile Arg Asp Asn Glu Arg Ser Gly Arg Ala Arg Val His 
        195                 200                 205             


Val Ser Glu Glu Gly Thr Glu Pro Glu Ala Met Leu Gln Val Leu Gly 
    210                 215                 220                 


Pro Lys Pro Ala Leu Pro Ala Gly Thr Glu Asp Thr Ala Lys Glu Asp 
225                 230                 235                 240 


Ala Ala Asn Arg Lys Leu Ala Lys Leu Tyr Lys Val Ser Asn Gly Ala 
                245                 250                 255     


Gly Thr Met Ser Val Ser Leu Val Ala Asp Glu Asn Pro Phe Ala Gln 
            260                 265                 270         


Gly Ala Leu Lys Ser Glu Asp Cys Phe Ile Leu Asp His Gly Lys Asp 
        275                 280                 285             


Gly Lys Ile Phe Val Trp Lys Gly Lys Gln Ala Asn Thr Glu Glu Arg 
    290                 295                 300                 


Lys Ala Ala Leu Lys Thr Ala Ser Asp Phe Ile Thr Lys Met Asp Tyr 
305                 310                 315                 320 


Pro Lys Gln Thr Gln Val Ser Val Leu Pro Glu Gly Gly Glu Thr Pro 
                325                 330                 335     


Leu Phe Lys Gln Phe Phe Lys Asn Trp Arg Asp Pro Asp Gln Thr Asp 
            340                 345                 350         


Gly Leu Gly Leu Ser Tyr Leu Ser Ser His Ile Ala Asn Val Glu Arg 
        355                 360                 365             


Val Pro Phe Asp Ala Ala Thr Leu His Thr Ser Thr Ala Met Ala Ala 
    370                 375                 380                 


Gln His Gly Met Asp Asp Asp Gly Thr Gly Gln Lys Gln Ile Trp Arg 
385                 390                 395                 400 


Ile Glu Gly Ser Asn Lys Val Pro Val Asp Pro Ala Thr Tyr Gly Gln 
                405                 410                 415     


Phe Tyr Gly Gly Asp Ser Tyr Ile Ile Leu Tyr Asn Tyr Arg His Gly 
            420                 425                 430         


Gly Arg Gln Gly Gln Ile Ile Tyr Asn Trp Gln Gly Ala Gln Ser Thr 
        435                 440                 445             


Gln Asp Glu Val Ala Ala Ser Ala Ile Leu Thr Ala Gln Leu Asp Glu 
    450                 455                 460                 


Glu Leu Gly Gly Thr Pro Val Gln Ser Arg Val Val Gln Gly Lys Glu 
465                 470                 475                 480 


Pro Ala His Leu Met Ser Leu Phe Gly Gly Lys Pro Met Ile Ile Tyr 
                485                 490                 495     


Lys Gly Gly Thr Ser Arg Glu Gly Gly Gln Thr Ala Pro Ala Ser Thr 
            500                 505                 510         


Arg Leu Phe Gln Val Arg Ala Asn Ser Ala Gly Ala Thr Arg Ala Val 
        515                 520                 525             


Glu Val Leu Pro Lys Ala Gly Ala Leu Asn Ser Asn Asp Ala Phe Val 
    530                 535                 540                 


Leu Lys Thr Pro Ser Ala Ala Tyr Leu Trp Val Gly Thr Gly Ala Ser 
545                 550                 555                 560 


Glu Ala Glu Lys Thr Gly Ala Gln Glu Leu Leu Arg Val Leu Arg Ala 
                565                 570                 575     


Gln Pro Val Gln Val Ala Glu Gly Ser Glu Pro Asp Gly Phe Trp Glu 
            580                 585                 590         


Ala Leu Gly Gly Lys Ala Ala Tyr Arg Thr Ser Pro Arg Leu Lys Asp 
        595                 600                 605             


Lys Lys Met Asp Ala His Pro Pro Arg Leu Phe Ala Cys Ser Asn Lys 
    610                 615                 620                 


Ile Gly Arg Phe Val Ile Glu Glu Val Pro Gly Glu Leu Met Gln Glu 
625                 630                 635                 640 


Asp Leu Ala Thr Asp Asp Val Met Leu Leu Asp Thr Trp Asp Gln Val 
                645                 650                 655     


Phe Val Trp Val Gly Lys Asp Ser Gln Glu Glu Glu Lys Thr Glu Ala 
            660                 665                 670         


Leu Thr Ser Ala Lys Arg Tyr Ile Glu Thr Asp Pro Ala Asn Arg Asp 
        675                 680                 685             


Arg Arg Thr Pro Ile Thr Val Val Lys Gln Gly Phe Glu Pro Pro Ser 
    690                 695                 700                 


Phe Val Gly Trp Phe Leu Gly Trp Asp Asp Asp Tyr Trp Ser Val Asp 
705                 710                 715                 720 


Pro Leu Asp Arg Ala Met Ala Glu Leu Ala Ala 
                725                 730     


<210>  1205
<211>  142
<212>  PRT
<213>  Human

<400>  1205

Met Val Leu Ser Pro Ala Asp Lys Thr Asn Val Lys Ala Ala Trp Gly 
1               5                   10                  15      


Lys Val Gly Ala His Ala Gly Glu Tyr Gly Ala Glu Ala Leu Glu Arg 
            20                  25                  30          


Met Phe Leu Ser Phe Pro Thr Thr Lys Thr Tyr Phe Pro His Phe Asp 
        35                  40                  45              


Leu Ser His Gly Ser Ala Gln Val Lys Gly His Gly Lys Lys Val Ala 
    50                  55                  60                  


Asp Ala Leu Thr Asn Ala Val Ala His Val Asp Asp Met Pro Asn Ala 
65                  70                  75                  80  


Leu Ser Ala Leu Ser Asp Leu His Ala His Lys Leu Arg Val Asp Pro 
                85                  90                  95      


Val Asn Phe Lys Leu Leu Ser His Cys Leu Leu Val Thr Leu Ala Ala 
            100                 105                 110         


His Leu Pro Ala Glu Phe Thr Pro Ala Val His Ala Ser Leu Asp Lys 
        115                 120                 125             


Phe Leu Ala Ser Val Ser Thr Val Leu Thr Ser Lys Tyr Arg 
    130                 135                 140         


<210>  1206
<211>  142
<212>  PRT
<213>  Human

<400>  1206

Met Val Leu Ser Pro Ala Asp Lys Thr Asn Val Lys Ala Ala Trp Gly 
1               5                   10                  15      


Lys Val Gly Ala His Ala Gly Glu Tyr Gly Ala Glu Ala Leu Glu Arg 
            20                  25                  30          


Met Phe Leu Ser Phe Pro Thr Thr Lys Thr Tyr Phe Pro His Phe Asp 
        35                  40                  45              


Leu Ser His Gly Ser Ala Gln Val Lys Gly His Gly Lys Lys Val Ala 
    50                  55                  60                  


Asp Ala Leu Thr Asn Ala Val Ala His Val Asp Asp Met Pro Asn Ala 
65                  70                  75                  80  


Leu Ser Ala Leu Ser Asp Leu His Ala His Lys Leu Arg Val Asp Pro 
                85                  90                  95      


Val Asn Phe Lys Leu Leu Ser His Cys Leu Leu Val Thr Leu Ala Ala 
            100                 105                 110         


His Leu Pro Ala Glu Phe Thr Pro Ala Val His Ala Ser Leu Asp Lys 
        115                 120                 125             


Phe Leu Ala Ser Val Ser Thr Val Leu Thr Ser Lys Tyr Arg 
    130                 135                 140         


<210>  1207
<211>  166
<212>  PRT
<213>  Human

<400>  1207

Met Ala Pro Ser Thr Val Ala Val Glu Leu Leu Ser Pro Lys Glu Lys 
1               5                   10                  15      


Asn Arg Leu Arg Lys Pro Val Val Glu Lys Met Arg Arg Asp Arg Ile 
            20                  25                  30          


Asn Ser Ser Ile Glu Gln Leu Lys Leu Leu Leu Glu Gln Glu Phe Ala 
        35                  40                  45              


Arg His Gln Pro Asn Ser Lys Leu Glu Lys Ala Asp Ile Leu Glu Met 
    50                  55                  60                  


Ala Val Ser Tyr Leu Lys His Ser Lys Ala Phe Val Ala Ala Ala Gly 
65                  70                  75                  80  


Pro Lys Ser Leu His Gln Asp Tyr Ser Glu Gly Tyr Ser Trp Cys Leu 
                85                  90                  95      


Gln Glu Ala Val Gln Phe Leu Thr Leu His Ala Ala Ser Asp Thr Gln 
            100                 105                 110         


Met Lys Leu Leu Tyr His Phe Gln Arg Pro Pro Ala Ala Pro Ala Ala 
        115                 120                 125             


Pro Ala Lys Glu Pro Lys Ala Pro Gly Ala Ala Pro Pro Pro Ala Leu 
    130                 135                 140                 


Ser Ala Lys Ala Thr Ala Ala Ala Ala Ala Ala His Gln Pro Ala Cys 
145                 150                 155                 160 


Gly Leu Trp Arg Pro Trp 
                165     


<210>  1208
<211>  999
<212>  PRT
<213>  Human

<400>  1208

Met Ala Asp Lys Val Arg Arg Gln Arg Pro Arg Arg Arg Val Cys Trp 
1               5                   10                  15      


Ala Leu Val Ala Val Leu Leu Ala Asp Leu Leu Ala Leu Ser Asp Thr 
            20                  25                  30          


Leu Ala Val Met Ser Val Asp Leu Gly Ser Glu Ser Met Lys Val Ala 
        35                  40                  45              


Ile Val Lys Pro Gly Val Pro Met Glu Ile Val Leu Asn Lys Glu Ser 
    50                  55                  60                  


Arg Arg Lys Thr Pro Val Ile Val Thr Leu Lys Glu Asn Glu Arg Phe 
65                  70                  75                  80  


Phe Gly Asp Ser Ala Ala Ser Met Ala Ile Lys Asn Pro Lys Ala Thr 
                85                  90                  95      


Leu Arg Tyr Phe Gln His Leu Leu Gly Lys Gln Ala Asp Asn Pro His 
            100                 105                 110         


Val Ala Leu Tyr Gln Ala Arg Phe Pro Glu His Glu Leu Thr Phe Asp 
        115                 120                 125             


Pro Gln Arg Gln Thr Val His Phe Gln Ile Ser Ser Gln Leu Gln Phe 
    130                 135                 140                 


Ser Pro Glu Glu Val Leu Gly Met Val Leu Asn Tyr Ser Arg Ser Leu 
145                 150                 155                 160 


Ala Glu Asp Phe Ala Glu Gln Pro Ile Lys Asp Ala Val Ile Thr Val 
                165                 170                 175     


Pro Val Phe Phe Asn Gln Ala Glu Arg Arg Ala Val Leu Gln Ala Ala 
            180                 185                 190         


Arg Met Ala Gly Leu Lys Val Leu Gln Leu Ile Asn Asp Asn Thr Ala 
        195                 200                 205             


Thr Ala Leu Ser Tyr Gly Val Phe Arg Arg Lys Asp Ile Asn Thr Thr 
    210                 215                 220                 


Ala Gln Asn Ile Met Phe Tyr Asp Met Gly Ser Gly Ser Thr Val Cys 
225                 230                 235                 240 


Thr Ile Val Thr Tyr Gln Met Val Lys Thr Lys Glu Ala Gly Met Gln 
                245                 250                 255     


Pro Gln Leu Gln Ile Arg Gly Val Gly Phe Asp Arg Thr Leu Gly Gly 
            260                 265                 270         


Leu Glu Met Glu Leu Arg Leu Arg Glu Arg Leu Ala Gly Leu Phe Asn 
        275                 280                 285             


Glu Gln Arg Lys Gly Gln Arg Ala Lys Asp Val Arg Glu Asn Pro Arg 
    290                 295                 300                 


Ala Met Ala Lys Leu Leu Arg Glu Ala Asn Arg Leu Lys Thr Val Leu 
305                 310                 315                 320 


Ser Ala Asn Ala Asp His Met Ala Gln Ile Glu Gly Leu Met Asp Asp 
                325                 330                 335     


Val Asp Phe Lys Ala Lys Val Thr Arg Val Glu Phe Glu Glu Leu Cys 
            340                 345                 350         


Ala Asp Leu Phe Glu Arg Val Pro Gly Pro Val Gln Gln Ala Leu Gln 
        355                 360                 365             


Ser Ala Glu Met Ser Leu Asp Glu Ile Glu Gln Val Ile Leu Val Gly 
    370                 375                 380                 


Gly Ala Thr Arg Val Pro Arg Val Gln Glu Val Leu Leu Lys Ala Val 
385                 390                 395                 400 


Gly Lys Glu Glu Leu Gly Lys Asn Ile Asn Ala Asp Glu Ala Ala Ala 
                405                 410                 415     


Met Gly Ala Val Tyr Gln Ala Ala Ala Leu Ser Lys Ala Phe Lys Val 
            420                 425                 430         


Lys Pro Phe Val Val Arg Asp Ala Val Val Tyr Pro Ile Leu Val Glu 
        435                 440                 445             


Phe Thr Arg Glu Val Glu Glu Glu Pro Gly Ile His Ser Leu Lys His 
    450                 455                 460                 


Asn Lys Arg Val Leu Phe Ser Arg Met Gly Pro Tyr Pro Gln Arg Lys 
465                 470                 475                 480 


Val Ile Thr Phe Asn Arg Tyr Ser His Asp Phe Asn Phe His Ile Asn 
                485                 490                 495     


Tyr Gly Asp Leu Gly Phe Leu Gly Pro Glu Asp Leu Arg Val Phe Gly 
            500                 505                 510         


Ser Gln Asn Leu Thr Thr Val Lys Leu Lys Gly Val Gly Asp Ser Phe 
        515                 520                 525             


Lys Lys Tyr Pro Asp Tyr Glu Ser Lys Gly Ile Lys Ala His Phe Asn 
    530                 535                 540                 


Leu Asp Glu Ser Gly Val Leu Ser Leu Asp Arg Val Glu Ser Val Phe 
545                 550                 555                 560 


Glu Thr Leu Val Glu Asp Ser Ala Glu Glu Glu Ser Thr Leu Thr Lys 
                565                 570                 575     


Leu Gly Asn Thr Ile Ser Ser Leu Phe Gly Gly Gly Thr Thr Pro Asp 
            580                 585                 590         


Ala Lys Glu Asn Gly Thr Asp Thr Val Gln Glu Glu Glu Glu Ser Pro 
        595                 600                 605             


Ala Glu Gly Ser Lys Asp Glu Pro Gly Glu Gln Val Glu Leu Lys Glu 
    610                 615                 620                 


Glu Ala Glu Ala Pro Val Glu Asp Gly Ser Gln Pro Pro Pro Pro Glu 
625                 630                 635                 640 


Pro Lys Gly Asp Ala Thr Pro Glu Gly Glu Lys Ala Thr Glu Lys Glu 
                645                 650                 655     


Asn Gly Asp Lys Ser Glu Ala Gln Lys Pro Ser Glu Lys Ala Glu Ala 
            660                 665                 670         


Gly Pro Glu Gly Val Ala Pro Ala Pro Glu Gly Glu Lys Lys Gln Lys 
        675                 680                 685             


Pro Ala Arg Lys Arg Arg Met Val Glu Glu Ile Gly Val Glu Leu Val 
    690                 695                 700                 


Val Leu Asp Leu Pro Asp Leu Pro Glu Asp Lys Leu Ala Gln Ser Val 
705                 710                 715                 720 


Gln Lys Leu Gln Asp Leu Thr Leu Arg Asp Leu Glu Lys Gln Glu Arg 
                725                 730                 735     


Glu Lys Ala Ala Asn Ser Leu Glu Ala Phe Ile Phe Glu Thr Gln Asp 
            740                 745                 750         


Lys Leu Tyr Gln Pro Glu Tyr Gln Glu Val Ser Thr Glu Glu Gln Arg 
        755                 760                 765             


Glu Glu Ile Ser Gly Lys Leu Ser Ala Ala Ser Thr Trp Leu Glu Asp 
    770                 775                 780                 


Glu Gly Val Gly Ala Thr Thr Val Met Leu Lys Glu Lys Leu Ala Glu 
785                 790                 795                 800 


Leu Arg Lys Leu Cys Gln Gly Leu Phe Phe Arg Val Glu Glu Arg Lys 
                805                 810                 815     


Lys Trp Pro Glu Arg Leu Ser Ala Leu Asp Asn Leu Leu Asn His Ser 
            820                 825                 830         


Ser Met Phe Leu Lys Gly Ala Arg Leu Ile Pro Glu Met Asp Gln Ile 
        835                 840                 845             


Phe Thr Glu Val Glu Met Thr Thr Leu Glu Lys Val Ile Asn Glu Thr 
    850                 855                 860                 


Trp Ala Trp Lys Asn Ala Thr Leu Ala Glu Gln Ala Lys Leu Pro Ala 
865                 870                 875                 880 


Thr Glu Lys Pro Val Leu Leu Ser Lys Asp Ile Glu Ala Lys Met Met 
                885                 890                 895     


Ala Leu Asp Arg Glu Val Gln Tyr Leu Leu Asn Lys Ala Lys Phe Thr 
            900                 905                 910         


Lys Pro Arg Pro Arg Pro Lys Asp Lys Asn Gly Thr Arg Ala Glu Pro 
        915                 920                 925             


Pro Leu Asn Ala Ser Ala Ser Asp Gln Gly Glu Lys Val Ile Pro Pro 
    930                 935                 940                 


Ala Gly Gln Thr Glu Asp Ala Glu Pro Ile Ser Glu Pro Glu Lys Val 
945                 950                 955                 960 


Glu Thr Gly Ser Glu Pro Gly Asp Thr Glu Pro Leu Glu Leu Gly Gly 
                965                 970                 975     


Pro Gly Ala Glu Pro Glu Gln Lys Glu Gln Ser Thr Gly Gln Lys Arg 
            980                 985                 990         


Pro Leu Lys Asn Asp Glu Leu 
        995                 


<210>  1209
<211>  390
<212>  PRT
<213>  Human

<400>  1209

Met Arg Gly Asp Arg Gly Arg Gly Arg Gly Gly Arg Phe Gly Ser Arg 
1               5                   10                  15      


Gly Gly Pro Gly Gly Gly Phe Arg Pro Phe Val Pro His Ile Pro Phe 
            20                  25                  30          


Asp Phe Tyr Leu Cys Glu Met Ala Phe Pro Arg Val Lys Pro Ala Pro 
        35                  40                  45              


Asp Glu Thr Ser Phe Ser Glu Ala Leu Leu Lys Arg Asn Gln Asp Leu 
    50                  55                  60                  


Ala Pro Asn Ser Ala Glu Gln Ala Ser Ile Leu Ser Leu Val Thr Lys 
65                  70                  75                  80  


Ile Asn Asn Val Ile Asp Asn Leu Ile Val Ala Pro Gly Thr Phe Glu 
                85                  90                  95      


Val Gln Ile Glu Glu Val Arg Gln Val Gly Ser Tyr Lys Lys Gly Thr 
            100                 105                 110         


Met Thr Thr Gly His Asn Val Ala Asp Leu Val Val Ile Leu Lys Ile 
        115                 120                 125             


Leu Pro Thr Leu Glu Ala Val Ala Ala Leu Gly Asn Lys Val Val Glu 
    130                 135                 140                 


Ser Leu Arg Ala Gln Asp Pro Ser Glu Val Leu Thr Met Leu Thr Asn 
145                 150                 155                 160 


Glu Thr Gly Phe Glu Ile Ser Ser Ser Asp Ala Thr Val Lys Ile Leu 
                165                 170                 175     


Ile Thr Thr Val Pro Pro Asn Leu Arg Lys Leu Asp Pro Glu Leu His 
            180                 185                 190         


Leu Asp Ile Lys Val Leu Gln Ser Ala Leu Ala Ala Ile Arg His Ala 
        195                 200                 205             


Arg Trp Phe Glu Glu Asn Ala Ser Gln Ser Thr Val Lys Val Leu Ile 
    210                 215                 220                 


Arg Leu Leu Lys Asp Leu Arg Ile Arg Phe Pro Gly Phe Glu Pro Leu 
225                 230                 235                 240 


Thr Pro Trp Ile Leu Asp Leu Leu Gly His Tyr Ala Val Met Asn Asn 
                245                 250                 255     


Pro Thr Arg Gln Pro Leu Ala Leu Asn Val Ala Tyr Arg Arg Cys Leu 
            260                 265                 270         


Gln Ile Leu Ala Ala Gly Leu Phe Leu Pro Gly Ser Val Gly Ile Thr 
        275                 280                 285             


Asp Pro Cys Glu Ser Gly Asn Phe Arg Val His Thr Val Met Thr Leu 
    290                 295                 300                 


Glu Gln Gln Asp Met Val Cys Tyr Thr Ala Gln Thr Leu Val Arg Ile 
305                 310                 315                 320 


Leu Ser His Gly Gly Phe Arg Lys Ile Leu Gly Gln Glu Gly Asp Ala 
                325                 330                 335     


Ser Tyr Leu Ala Ser Glu Ile Ser Thr Trp Asp Gly Val Ile Val Thr 
            340                 345                 350         


Pro Ser Glu Lys Ala Tyr Glu Lys Pro Pro Glu Lys Lys Glu Gly Glu 
        355                 360                 365             


Glu Glu Glu Glu Asn Thr Glu Glu Pro Pro Gln Gly Glu Glu Glu Glu 
    370                 375                 380                 


Ser Met Glu Thr Gln Glu 
385                 390 


<210>  1210
<211>  1682
<212>  PRT
<213>  Human

<400>  1210

Met His Arg Ala Val Asp Pro Pro Gly Ala Arg Ala Ala Arg Glu Ala 
1               5                   10                  15      


Phe Ala Leu Gly Gly Leu Ser Cys Ala Gly Ala Trp Ser Ser Cys Pro 
            20                  25                  30          


Pro His Pro Pro Pro Arg Ser Ala Trp Leu Pro Gly Gly Arg Cys Ser 
        35                  40                  45              


Ala Ser Ile Gly Gln Pro Pro Leu Pro Ala Pro Leu Pro Pro Ser His 
    50                  55                  60                  


Gly Ser Ser Ser Gly His Pro Ser Lys Pro Tyr Tyr Ala Pro Gly Ala 
65                  70                  75                  80  


Pro Thr Pro Arg Pro Leu His Gly Lys Leu Glu Ser Leu His Gly Cys 
                85                  90                  95      


Val Gln Ala Leu Leu Arg Glu Pro Ala Gln Pro Gly Leu Trp Glu Gln 
            100                 105                 110         


Leu Gly Gln Leu Tyr Glu Ser Glu His Asp Ser Glu Glu Ala Thr Arg 
        115                 120                 125             


Cys Tyr His Ser Ala Leu Arg Tyr Gly Gly Ser Phe Ala Glu Leu Gly 
    130                 135                 140                 


Pro Arg Ile Gly Arg Leu Gln Gln Ala Gln Leu Trp Asn Phe His Thr 
145                 150                 155                 160 


Gly Ser Cys Gln His Arg Ala Lys Val Leu Pro Pro Leu Glu Gln Val 
                165                 170                 175     


Trp Asn Leu Leu His Leu Glu His Lys Arg Asn Tyr Gly Ala Lys Arg 
            180                 185                 190         


Gly Gly Pro Pro Val Lys Arg Ala Ala Glu Pro Pro Val Val Gln Pro 
        195                 200                 205             


Val Pro Pro Ala Ala Leu Ser Gly Pro Ser Gly Glu Glu Gly Leu Ser 
    210                 215                 220                 


Pro Gly Gly Lys Arg Arg Arg Gly Cys Asn Ser Glu Gln Thr Gly Leu 
225                 230                 235                 240 


Pro Pro Gly Leu Pro Leu Pro Pro Pro Pro Leu Pro Pro Pro Pro Pro 
                245                 250                 255     


Pro Pro Pro Pro Pro Pro Pro Pro Leu Pro Gly Leu Ala Thr Ser Pro 
            260                 265                 270         


Pro Phe Gln Leu Thr Lys Pro Gly Leu Trp Ser Thr Leu His Gly Asp 
        275                 280                 285             


Ala Trp Gly Pro Glu Arg Lys Gly Ser Ala Pro Pro Glu Arg Gln Glu 
    290                 295                 300                 


Gln Arg His Ser Leu Pro His Pro Tyr Pro Tyr Pro Ala Pro Ala Tyr 
305                 310                 315                 320 


Thr Ala His Pro Pro Gly His Arg Leu Val Pro Ala Ala Pro Pro Gly 
                325                 330                 335     


Pro Gly Pro Arg Pro Pro Gly Ala Glu Ser His Gly Cys Leu Pro Ala 
            340                 345                 350         


Thr Arg Pro Pro Gly Ser Asp Leu Arg Glu Ser Arg Val Gln Arg Ser 
        355                 360                 365             


Arg Met Asp Ser Ser Val Ser Pro Ala Ala Thr Thr Ala Cys Val Pro 
    370                 375                 380                 


Tyr Ala Pro Ser Arg Pro Pro Gly Leu Pro Gly Thr Thr Thr Ser Ser 
385                 390                 395                 400 


Ser Ser Ser Ser Ser Ser Asn Thr Gly Leu Arg Gly Val Glu Pro Asn 
                405                 410                 415     


Pro Gly Ile Pro Gly Ala Asp His Tyr Gln Thr Pro Ala Leu Glu Val 
            420                 425                 430         


Ser His His Gly Arg Leu Gly Pro Ser Ala His Ser Ser Arg Lys Pro 
        435                 440                 445             


Phe Leu Gly Ala Pro Ala Ala Thr Pro His Leu Ser Leu Pro Pro Gly 
    450                 455                 460                 


Pro Ser Ser Pro Pro Pro Pro Pro Cys Pro Arg Leu Leu Arg Pro Pro 
465                 470                 475                 480 


Pro Pro Pro Ala Trp Leu Lys Gly Pro Ala Cys Arg Ala Ala Arg Glu 
                485                 490                 495     


Asp Gly Glu Ile Leu Glu Glu Leu Phe Phe Gly Thr Glu Gly Pro Pro 
            500                 505                 510         


Arg Pro Ala Pro Pro Pro Leu Pro His Arg Glu Gly Phe Leu Gly Pro 
        515                 520                 525             


Pro Ala Ser Arg Phe Ser Val Gly Thr Gln Asp Ser His Thr Pro Pro 
    530                 535                 540                 


Thr Pro Pro Thr Pro Thr Thr Ser Ser Ser Asn Ser Asn Ser Gly Ser 
545                 550                 555                 560 


His Ser Ser Ser Pro Ala Gly Pro Val Ser Phe Pro Pro Pro Pro Tyr 
                565                 570                 575     


Leu Ala Arg Ser Ile Asp Pro Leu Pro Arg Pro Pro Ser Pro Ala Gln 
            580                 585                 590         


Asn Pro Gln Asp Pro Pro Leu Val Pro Leu Thr Leu Ala Leu Pro Pro 
        595                 600                 605             


Ala Pro Pro Ser Ser Cys His Gln Asn Thr Ser Gly Ser Phe Arg Arg 
    610                 615                 620                 


Pro Glu Ser Pro Arg Pro Arg Val Ser Phe Pro Lys Thr Pro Glu Val 
625                 630                 635                 640 


Gly Pro Gly Pro Pro Pro Gly Pro Leu Ser Lys Ala Pro Gln Pro Val 
                645                 650                 655     


Pro Pro Gly Val Gly Glu Leu Pro Ala Arg Gly Pro Arg Leu Phe Asp 
            660                 665                 670         


Phe Pro Pro Thr Pro Leu Glu Asp Gln Phe Glu Glu Pro Ala Glu Phe 
        675                 680                 685             


Lys Ile Leu Pro Asp Gly Leu Ala Asn Ile Met Lys Met Leu Asp Glu 
    690                 695                 700                 


Ser Ile Arg Lys Glu Glu Glu Gln Gln Gln His Glu Ala Gly Val Ala 
705                 710                 715                 720 


Pro Gln Pro Pro Leu Lys Glu Pro Phe Ala Ser Leu Gln Ser Pro Phe 
                725                 730                 735     


Pro Thr Asp Thr Ala Pro Thr Thr Thr Ala Pro Ala Val Ala Val Thr 
            740                 745                 750         


Thr Thr Thr Thr Thr Thr Thr Thr Thr Thr Ala Thr Gln Glu Glu Glu 
        755                 760                 765             


Lys Lys Pro Pro Pro Ala Leu Pro Pro Pro Pro Pro Leu Ala Lys Phe 
    770                 775                 780                 


Pro Pro Pro Ser Gln Pro Gln Pro Pro Pro Pro Pro Pro Pro Ser Pro 
785                 790                 795                 800 


Ala Ser Leu Leu Lys Ser Leu Ala Ser Val Leu Glu Gly Gln Lys Tyr 
                805                 810                 815     


Cys Tyr Arg Gly Thr Gly Ala Ala Val Ser Thr Arg Pro Gly Pro Leu 
            820                 825                 830         


Pro Thr Thr Gln Tyr Ser Pro Gly Pro Pro Ser Gly Ala Thr Ala Leu 
        835                 840                 845             


Pro Pro Thr Ser Ala Ala Pro Ser Ala Gln Gly Ser Pro Gln Pro Ser 
    850                 855                 860                 


Ala Ser Ser Ser Ser Gln Phe Ser Thr Ser Gly Gly Pro Trp Ala Arg 
865                 870                 875                 880 


Glu Arg Arg Ala Gly Glu Glu Pro Val Pro Gly Pro Met Thr Pro Thr 
                885                 890                 895     


Gln Pro Pro Pro Pro Leu Ser Leu Pro Pro Ala Arg Ser Glu Ser Glu 
            900                 905                 910         


Val Leu Glu Glu Ile Ser Arg Ala Cys Glu Thr Leu Val Glu Arg Val 
        915                 920                 925             


Gly Arg Ser Ala Thr Asp Pro Ala Asp Pro Val Asp Thr Ala Glu Pro 
    930                 935                 940                 


Ala Asp Ser Gly Thr Glu Arg Leu Leu Pro Pro Ala Gln Ala Lys Glu 
945                 950                 955                 960 


Glu Ala Gly Gly Val Ala Ala Val Ser Gly Ser Cys Lys Arg Arg Gln 
                965                 970                 975     


Lys Glu His Gln Lys Glu His Arg Arg His Arg Arg Ala Cys Lys Asp 
            980                 985                 990         


Ser Val Gly Arg Arg Pro Arg Glu  Gly Arg Ala Lys Ala  Lys Ala Lys 
        995                 1000                 1005             


Val Pro  Lys Glu Lys Ser Arg  Arg Val Leu Gly Asn  Leu Asp Leu 
    1010                 1015                 1020             


Gln Ser  Glu Glu Ile Gln Gly  Arg Glu Lys Ser Arg  Pro Asp Leu 
    1025                 1030                 1035             


Gly Gly  Ala Ser Lys Ala Lys  Pro Pro Thr Ala Pro  Ala Pro Pro 
    1040                 1045                 1050             


Ser Ala  Pro Ala Pro Ser Ala  Gln Pro Thr Pro Pro  Ser Ala Ser 
    1055                 1060                 1065             


Val Pro  Gly Lys Lys Ala Arg  Glu Glu Ala Pro Gly  Pro Pro Gly 
    1070                 1075                 1080             


Val Ser  Arg Ala Asp Met Leu  Lys Leu Arg Ser Leu  Ser Glu Gly 
    1085                 1090                 1095             


Pro Pro  Lys Glu Leu Lys Ile  Arg Leu Ile Lys Val  Glu Ser Gly 
    1100                 1105                 1110             


Asp Lys  Glu Thr Phe Ile Ala  Ser Glu Val Glu Glu  Arg Arg Leu 
    1115                 1120                 1125             


Arg Met  Ala Asp Leu Thr Ile  Ser His Cys Ala Ala  Asp Val Val 
    1130                 1135                 1140             


Arg Ala  Ser Arg Asn Ala Lys  Val Lys Gly Lys Phe  Arg Glu Ser 
    1145                 1150                 1155             


Tyr Leu  Ser Pro Ala Gln Ser  Val Lys Pro Lys Ile  Asn Thr Glu 
    1160                 1165                 1170             


Glu Lys  Leu Pro Arg Glu Lys  Leu Asn Pro Pro Thr  Pro Ser Ile 
    1175                 1180                 1185             


Tyr Leu  Glu Ser Lys Arg Asp  Ala Phe Ser Pro Val  Leu Leu Gln 
    1190                 1195                 1200             


Phe Cys  Thr Asp Pro Arg Asn  Pro Ile Thr Val Ile  Arg Gly Leu 
    1205                 1210                 1215             


Ala Gly  Ser Leu Arg Leu Asn  Leu Gly Leu Phe Ser  Thr Lys Thr 
    1220                 1225                 1230             


Leu Val  Glu Ala Ser Gly Glu  His Thr Val Glu Val  Arg Thr Gln 
    1235                 1240                 1245             


Val Gln  Gln Pro Ser Asp Glu  Asn Trp Asp Leu Thr  Gly Thr Arg 
    1250                 1255                 1260             


Gln Ile  Trp Pro Cys Glu Ser  Ser Arg Ser His Thr  Thr Ile Ala 
    1265                 1270                 1275             


Lys Tyr  Ala Gln Tyr Gln Ala  Ser Ser Phe Gln Glu  Ser Leu Gln 
    1280                 1285                 1290             


Glu Glu  Lys Glu Ser Glu Asp  Glu Glu Ser Glu Glu  Pro Asp Ser 
    1295                 1300                 1305             


Thr Thr  Gly Thr Pro Pro Ser  Ser Ala Pro Asp Pro  Lys Asn His 
    1310                 1315                 1320             


His Ile  Ile Lys Phe Gly Thr  Asn Ile Asp Leu Ser  Asp Ala Lys 
    1325                 1330                 1335             


Arg Trp  Lys Pro Gln Leu Gln  Glu Leu Leu Lys Leu  Pro Ala Phe 
    1340                 1345                 1350             


Met Arg  Val Thr Ser Thr Gly  Asn Met Leu Ser His  Val Gly His 
    1355                 1360                 1365             


Thr Ile  Leu Gly Met Asn Thr  Val Gln Leu Tyr Met  Lys Val Pro 
    1370                 1375                 1380             


Gly Ser  Arg Thr Pro Gly His  Gln Glu Asn Asn Asn  Phe Cys Ser 
    1385                 1390                 1395             


Val Asn  Ile Asn Ile Gly Pro  Gly Asp Cys Glu Trp  Phe Ala Val 
    1400                 1405                 1410             


His Glu  His Tyr Trp Glu Thr  Ile Ser Ala Phe Cys  Asp Arg His 
    1415                 1420                 1425             


Gly Val  Asp Tyr Leu Thr Gly  Ser Trp Trp Pro Ile  Leu Asp Asp 
    1430                 1435                 1440             


Leu Tyr  Ala Ser Asn Ile Pro  Val Tyr Arg Phe Val  Gln Arg Pro 
    1445                 1450                 1455             


Gly Asp  Leu Val Trp Ile Asn  Ala Gly Thr Val His  Trp Val Gln 
    1460                 1465                 1470             


Ala Thr  Gly Trp Cys Asn Asn  Ile Ala Trp Asn Val  Gly Pro Leu 
    1475                 1480                 1485             


Thr Ala  Tyr Gln Tyr Gln Leu  Ala Leu Glu Arg Tyr  Glu Trp Asn 
    1490                 1495                 1500             


Glu Val  Lys Asn Val Lys Ser  Ile Val Pro Met Ile  His Val Ser 
    1505                 1510                 1515             


Trp Asn  Val Ala Arg Thr Val  Lys Ile Ser Asp Pro  Asp Leu Phe 
    1520                 1525                 1530             


Lys Met  Ile Lys Phe Cys Leu  Leu Gln Ser Met Lys  His Cys Gln 
    1535                 1540                 1545             


Val Gln  Arg Glu Ser Leu Val  Arg Ala Gly Lys Lys  Ile Ala Tyr 
    1550                 1555                 1560             


Gln Gly  Arg Val Lys Asp Glu  Pro Ala Tyr Tyr Cys  Asn Glu Cys 
    1565                 1570                 1575             


Asp Val  Glu Val Phe Asn Ile  Leu Phe Val Thr Ser  Glu Asn Gly 
    1580                 1585                 1590             


Ser Arg  Asn Thr Tyr Leu Val  His Cys Glu Gly Cys  Ala Arg Arg 
    1595                 1600                 1605             


Arg Ser  Ala Gly Leu Gln Gly  Val Val Val Leu Glu  Gln Tyr Arg 
    1610                 1615                 1620             


Thr Glu  Glu Leu Ala Gln Ala  Tyr Asp Ala Phe Thr  Leu Val Arg 
    1625                 1630                 1635             


Ala Arg  Arg Ala Arg Gly Gln  Arg Arg Arg Ala Leu  Gly Gln Ala 
    1640                 1645                 1650             


Ala Gly  Thr Gly Phe Gly Ser  Pro Ala Ala Pro Phe  Pro Glu Pro 
    1655                 1660                 1665             


Pro Pro  Ala Phe Ser Pro Gln  Ala Pro Ala Ser Thr  Ser Arg 
    1670                 1675                 1680         


<210>  1211
<211>  1943
<212>  PRT
<213>  Human

<400>  1211

Met Glu Glu Asn Glu Ser Gln Lys Cys Glu Pro Cys Leu Pro Tyr Ser 
1               5                   10                  15      


Ala Asp Arg Arg Gln Met Gln Glu Gln Gly Lys Gly Asn Leu His Val 
            20                  25                  30          


Thr Ser Pro Glu Asp Ala Glu Cys Arg Arg Thr Lys Glu Arg Leu Ser 
        35                  40                  45              


Asn Gly Asn Ser Arg Gly Ser Val Ser Lys Ser Ser Arg Asn Ile Pro 
    50                  55                  60                  


Arg Arg His Thr Leu Gly Gly Pro Arg Ser Ser Lys Glu Ile Leu Gly 
65                  70                  75                  80  


Met Gln Thr Ser Glu Met Asp Arg Lys Arg Glu Ala Phe Leu Glu His 
                85                  90                  95      


Leu Lys Gln Lys Tyr Pro His His Ala Ser Ala Ile Met Gly His Gln 
            100                 105                 110         


Glu Arg Leu Arg Asp Gln Thr Arg Ser Pro Lys Leu Ser His Ser Pro 
        115                 120                 125             


Gln Pro Pro Ser Leu Gly Asp Pro Val Glu His Leu Ser Glu Thr Ser 
    130                 135                 140                 


Ala Asp Ser Leu Glu Ala Met Ser Glu Gly Asp Ala Pro Thr Pro Phe 
145                 150                 155                 160 


Ser Arg Gly Ser Arg Thr Arg Ala Ser Leu Pro Val Val Arg Ser Thr 
                165                 170                 175     


Asn Gln Thr Lys Glu Arg Ser Leu Gly Val Leu Tyr Leu Gln Tyr Gly 
            180                 185                 190         


Asp Glu Thr Lys Gln Leu Arg Met Pro Asn Glu Ile Thr Ser Ala Asp 
        195                 200                 205             


Thr Ile Arg Ala Leu Phe Val Ser Ala Phe Pro Gln Gln Leu Thr Met 
    210                 215                 220                 


Lys Met Leu Glu Ser Pro Ser Val Ala Ile Tyr Ile Lys Asp Glu Ser 
225                 230                 235                 240 


Arg Asn Val Tyr Tyr Glu Leu Asn Asp Val Arg Asn Ile Gln Asp Arg 
                245                 250                 255     


Ser Leu Leu Lys Val Tyr Asn Lys Asp Pro Ala His Ala Phe Asn His 
            260                 265                 270         


Thr Pro Lys Thr Met Asn Gly Asp Met Arg Met Gln Arg Glu Leu Val 
        275                 280                 285             


Tyr Ala Arg Gly Asp Gly Pro Gly Ala Pro Arg Pro Gly Ser Thr Ala 
    290                 295                 300                 


His Pro Pro His Ala Ile Pro Asn Ser Pro Pro Ser Thr Pro Val Pro 
305                 310                 315                 320 


His Ser Met Pro Pro Ser Pro Ser Arg Ile Pro Tyr Gly Gly Thr Arg 
                325                 330                 335     


Ser Met Val Val Pro Gly Asn Ala Thr Ile Pro Arg Asp Arg Ile Ser 
            340                 345                 350         


Ser Leu Pro Val Ser Arg Pro Ile Ser Pro Ser Pro Ser Ala Ile Leu 
        355                 360                 365             


Glu Arg Arg Asp Val Lys Pro Asp Glu Asp Met Ser Gly Lys Asn Ile 
    370                 375                 380                 


Ala Met Tyr Arg Asn Glu Gly Phe Tyr Ala Asp Pro Tyr Leu Tyr His 
385                 390                 395                 400 


Glu Gly Arg Met Ser Ile Ala Ser Ser His Gly Gly His Pro Leu Asp 
                405                 410                 415     


Val Pro Asp His Ile Ile Ala Tyr His Arg Thr Ala Ile Arg Ser Ala 
            420                 425                 430         


Ser Ala Tyr Cys Asn Pro Ser Met Gln Ala Glu Met His Met Glu Gln 
        435                 440                 445             


Ser Leu Tyr Arg Gln Lys Ser Arg Lys Tyr Pro Asp Ser His Leu Pro 
    450                 455                 460                 


Thr Leu Gly Ser Lys Thr Pro Pro Ala Ser Pro His Arg Val Ser Asp 
465                 470                 475                 480 


Leu Arg Met Ile Asp Met His Ala His Tyr Asn Ala His Gly Pro Pro 
                485                 490                 495     


His Thr Met Gln Pro Asp Arg Ala Ser Pro Ser Arg Gln Ala Phe Lys 
            500                 505                 510         


Lys Glu Pro Gly Thr Leu Val Tyr Ile Glu Lys Pro Arg Ser Ala Ala 
        515                 520                 525             


Gly Leu Ser Ser Leu Val Asp Leu Gly Pro Pro Leu Met Glu Lys Gln 
    530                 535                 540                 


Val Phe Ala Tyr Ser Thr Ala Thr Ile Pro Lys Asp Arg Glu Thr Arg 
545                 550                 555                 560 


Glu Arg Met Gln Ala Met Glu Lys Gln Ile Ala Ser Leu Thr Gly Leu 
                565                 570                 575     


Val Gln Ser Ala Leu Phe Lys Gly Pro Ile Thr Ser Tyr Ser Lys Asp 
            580                 585                 590         


Ala Ser Ser Glu Lys Met Met Lys Thr Thr Ala Asn Arg Asn His Thr 
        595                 600                 605             


Asp Ser Ala Gly Thr Pro His Val Ser Gly Gly Lys Met Leu Ser Ala 
    610                 615                 620                 


Leu Glu Ser Thr Val Pro Pro Ser Gln Pro Pro Pro Val Gly Thr Ser 
625                 630                 635                 640 


Ala Ile His Met Ser Leu Leu Glu Met Arg Arg Ser Val Ala Glu Leu 
                645                 650                 655     


Arg Leu Gln Leu Gln Gln Met Arg Gln Leu Gln Leu Gln Asn Gln Glu 
            660                 665                 670         


Leu Leu Arg Ala Met Met Lys Lys Ala Glu Leu Glu Ile Ser Gly Lys 
        675                 680                 685             


Val Met Glu Thr Met Lys Arg Leu Glu Asp Pro Val Gln Arg Gln Arg 
    690                 695                 700                 


Val Leu Val Glu Gln Glu Arg Gln Lys Tyr Leu His Glu Glu Glu Lys 
705                 710                 715                 720 


Ile Val Lys Lys Leu Cys Glu Leu Glu Asp Phe Val Glu Asp Leu Lys 
                725                 730                 735     


Lys Asp Ser Thr Ala Ala Ser Arg Leu Val Thr Leu Lys Asp Val Glu 
            740                 745                 750         


Asp Gly Ala Phe Leu Leu Arg Gln Val Gly Glu Ala Val Ala Thr Leu 
        755                 760                 765             


Lys Gly Glu Phe Pro Thr Leu Gln Asn Lys Met Arg Ala Ile Leu Arg 
    770                 775                 780                 


Ile Glu Val Glu Ala Val Arg Phe Leu Lys Glu Glu Pro His Lys Leu 
785                 790                 795                 800 


Asp Ser Leu Leu Lys Arg Val Arg Ser Met Thr Asp Val Leu Thr Met 
                805                 810                 815     


Leu Arg Arg His Val Thr Asp Gly Leu Leu Lys Gly Thr Asp Ala Ala 
            820                 825                 830         


Gln Ala Ala Gln Tyr Met Ala Met Glu Lys Ala Thr Ala Ala Glu Val 
        835                 840                 845             


Leu Lys Ser Gln Glu Glu Ala Ala His Thr Ser Gly Gln Pro Phe His 
    850                 855                 860                 


Ser Thr Gly Ala Pro Gly Asp Ala Lys Ser Glu Val Val Pro Leu Ser 
865                 870                 875                 880 


Gly Met Met Val Arg His Ala Gln Ser Ser Pro Val Val Ile Gln Pro 
                885                 890                 895     


Ser Gln His Ser Val Ala Leu Leu Asn Pro Ala Gln Asn Leu Pro His 
            900                 905                 910         


Val Ala Ser Ser Pro Ala Val Pro Gln Glu Ala Thr Ser Thr Leu Gln 
        915                 920                 925             


Met Ser Gln Ala Pro Gln Ser Pro Gln Ile Pro Met Asn Gly Ser Ala 
    930                 935                 940                 


Met Gln Ser Leu Phe Ile Glu Glu Ile His Ser Val Ser Ala Lys Asn 
945                 950                 955                 960 


Arg Ala Val Ser Ile Glu Lys Ala Glu Lys Lys Trp Glu Glu Lys Arg 
                965                 970                 975     


Gln Asn Leu Asp His Tyr Asn Gly Lys Glu Phe Glu Lys Leu Leu Glu 
            980                 985                 990         


Glu Ala Gln Ala Asn Ile Met Lys  Ser Ile Pro Asn Leu  Glu Met Pro 
        995                 1000                 1005             


Pro Ala  Thr Gly Pro Leu Pro  Arg Gly Asp Ala Pro  Val Asp Lys 
    1010                 1015                 1020             


Val Glu  Leu Ser Glu Asp Ser  Pro Asn Ser Glu Gln  Asp Leu Glu 
    1025                 1030                 1035             


Lys Leu  Gly Gly Lys Ser Pro  Pro Pro Pro Pro Pro  Pro Pro Arg 
    1040                 1045                 1050             


Arg Ser  Tyr Leu Pro Gly Ser  Gly Leu Thr Thr Thr  Arg Ser Gly 
    1055                 1060                 1065             


Asp Val  Val Tyr Thr Gly Arg  Lys Glu Asn Ile Thr  Ala Lys Ala 
    1070                 1075                 1080             


Ser Ser  Glu Asp Ala Gly Pro  Ser Pro Gln Thr Arg  Ala Thr Lys 
    1085                 1090                 1095             


Tyr Pro  Ala Glu Glu Pro Ala  Ser Ala Trp Thr Pro  Ser Pro Pro 
    1100                 1105                 1110             


Pro Val  Thr Thr Ser Ser Ser  Lys Asp Glu Glu Glu  Glu Glu Glu 
    1115                 1120                 1125             


Glu Gly  Asp Lys Ile Met Ala  Glu Leu Gln Ala Phe  Gln Lys Cys 
    1130                 1135                 1140             


Ser Phe  Met Asp Val Asn Ser  Asn Ser His Ala Glu  Pro Ser Arg 
    1145                 1150                 1155             


Ala Asp  Ser His Val Lys Asp  Thr Arg Ser Gly Ala  Thr Val Pro 
    1160                 1165                 1170             


Pro Lys  Glu Lys Lys Asn Leu  Glu Phe Phe His Glu  Asp Val Arg 
    1175                 1180                 1185             


Lys Ser  Asp Val Glu Tyr Glu  Asn Gly Pro Gln Met  Glu Phe Gln 
    1190                 1195                 1200             


Lys Val  Thr Thr Gly Ala Val  Arg Pro Ser Asp Pro  Pro Lys Trp 
    1205                 1210                 1215             


Glu Arg  Gly Met Glu Asn Ser  Ile Ser Asp Ala Ser  Arg Thr Ser 
    1220                 1225                 1230             


Glu Tyr  Lys Thr Glu Ile Ile  Met Lys Glu Asn Ser  Ile Ser Asn 
    1235                 1240                 1245             


Met Ser  Leu Leu Arg Asp Ser  Arg Asn Tyr Ser Gln  Glu Thr Val 
    1250                 1255                 1260             


Pro Lys  Ala Ser Phe Gly Phe  Ser Gly Ile Ser Pro  Leu Glu Asp 
    1265                 1270                 1275             


Glu Ile  Asn Lys Gly Ser Lys  Ile Ser Gly Leu Gln  Tyr Ser Ile 
    1280                 1285                 1290             


Pro Asp  Thr Glu Asn Gln Thr  Leu Asn Tyr Gly Lys  Thr Lys Glu 
    1295                 1300                 1305             


Met Glu  Lys Gln Asn Thr Asp  Lys Cys His Val Ser  Ser His Thr 
    1310                 1315                 1320             


Arg Leu  Thr Glu Ser Ser Val  His Asp Phe Lys Thr  Glu Asp Gln 
    1325                 1330                 1335             


Glu Val  Ile Thr Thr Asp Phe  Gly Gln Val Val Leu  Arg Pro Lys 
    1340                 1345                 1350             


Glu Ala  Arg His Ala Asn Val  Asn Pro Asn Glu Asp  Gly Glu Ser 
    1355                 1360                 1365             


Ser Ser  Ser Ser Pro Thr Glu  Glu Asn Ala Ala Thr  Asp Asn Ile 
    1370                 1375                 1380             


Ala Phe  Met Ile Thr Glu Thr  Thr Val Gln Val Leu  Ser Ser Gly 
    1385                 1390                 1395             


Glu Val  His Asp Ile Val Ser  Gln Lys Gly Glu Asp  Ile Gln Thr 
    1400                 1405                 1410             


Val Asn  Ile Asp Ala Arg Lys  Glu Met Thr Pro Arg  Gln Glu Gly 
    1415                 1420                 1425             


Thr Asp  Asn Glu Asp Pro Val  Val Cys Leu Asp Lys  Lys Pro Val 
    1430                 1435                 1440             


Ile Ile  Ile Phe Asp Glu Pro  Met Asp Ile Arg Ser  Ala Tyr Lys 
    1445                 1450                 1455             


Arg Leu  Ser Thr Ile Phe Glu  Glu Cys Asp Glu Glu  Leu Glu Arg 
    1460                 1465                 1470             


Met Met  Met Glu Glu Lys Ile  Glu Glu Glu Glu Glu  Glu Glu Asn 
    1475                 1480                 1485             


Gly Asp  Ser Val Val Gln Asn  Asn Asn Thr Ser Gln  Met Ser His 
    1490                 1495                 1500             


Lys Lys  Val Ala Pro Gly Asn  Leu Arg Thr Gly Gln  Gln Val Glu 
    1505                 1510                 1515             


Thr Lys  Ser Gln Pro His Ser  Leu Ala Thr Glu Thr  Arg Asn Pro 
    1520                 1525                 1530             


Gly Gly  Gln Glu Met Asn Arg  Thr Glu Leu Asn Lys  Phe Ser His 
    1535                 1540                 1545             


Val Asp  Ser Pro Asn Ser Glu  Cys Lys Gly Glu Asp  Ala Thr Asp 
    1550                 1555                 1560             


Asp Gln  Phe Glu Ser Pro Lys  Lys Lys Phe Lys Phe  Lys Phe Pro 
    1565                 1570                 1575             


Lys Lys  Gln Leu Ala Ala Leu  Thr Gln Ala Ile Arg  Thr Gly Thr 
    1580                 1585                 1590             


Lys Thr  Gly Lys Lys Thr Leu  Gln Val Val Val Tyr  Glu Glu Glu 
    1595                 1600                 1605             


Glu Glu  Asp Gly Thr Leu Lys  Gln His Lys Glu Ala  Lys Arg Phe 
    1610                 1615                 1620             


Glu Ile  Ala Arg Ser Gln Pro  Glu Asp Thr Pro Glu  Asn Thr Val 
    1625                 1630                 1635             


Arg Arg  Gln Glu Gln Pro Ser  Ile Glu Ser Thr Ser  Pro Ile Ser 
    1640                 1645                 1650             


Arg Thr  Asp Glu Ile Arg Lys  Asn Thr Tyr Arg Thr  Leu Asp Ser 
    1655                 1660                 1665             


Leu Glu  Gln Thr Ile Lys Gln  Leu Glu Asn Thr Ile  Ser Glu Met 
    1670                 1675                 1680             


Ser Pro  Lys Ala Leu Val Asp  Thr Ser Cys Ser Ser  Asn Arg Asp 
    1685                 1690                 1695             


Ser Val  Ala Ser Ser Ser His  Ile Ala Gln Glu Ala  Ser Pro Arg 
    1700                 1705                 1710             


Pro Leu  Leu Val Pro Asp Glu  Gly Pro Thr Ala Leu  Glu Pro Pro 
    1715                 1720                 1725             


Thr Ser  Ile Pro Ser Ala Ser  Arg Lys Gly Ser Ser  Gly Ala Pro 
    1730                 1735                 1740             


Gln Thr  Ser Arg Met Pro Val  Pro Met Ser Ala Lys  Asn Arg Pro 
    1745                 1750                 1755             


Gly Thr  Leu Asp Lys Pro Gly  Lys Gln Ser Lys Leu  Gln Asp Pro 
    1760                 1765                 1770             


Arg Gln  Tyr Arg Gln Ala Asn  Gly Ser Ala Lys Lys  Ser Gly Gly 
    1775                 1780                 1785             


Asp Phe  Lys Pro Thr Ser Pro  Ser Leu Pro Ala Ser  Lys Ile Pro 
    1790                 1795                 1800             


Ala Leu  Ser Pro Ser Ser Gly  Lys Ser Ser Ser Leu  Pro Ser Ser 
    1805                 1810                 1815             


Ser Gly  Asp Ser Ser Asn Leu  Pro Asn Pro Pro Ala  Thr Lys Pro 
    1820                 1825                 1830             


Ser Ile  Ala Ser Asn Pro Leu  Ser Pro Gln Thr Gly  Pro Pro Ala 
    1835                 1840                 1845             


His Ser  Ala Ser Leu Ile Pro  Ser Val Ser Asn Gly  Ser Leu Lys 
    1850                 1855                 1860             


Phe Gln  Ser Leu Thr His Thr  Gly Lys Gly His His  Leu Ser Phe 
    1865                 1870                 1875             


Ser Pro  Gln Ser Gln Asn Gly  Arg Ala Pro Pro Pro  Leu Ser Phe 
    1880                 1885                 1890             


Ser Ser  Ser Pro Pro Ser Pro  Ala Ser Ser Val Ser  Leu Asn Gln 
    1895                 1900                 1905             


Gly Ala  Lys Gly Thr Arg Thr  Ile His Thr Pro Ser  Leu Thr Ser 
    1910                 1915                 1920             


Tyr Lys  Ala Gln Asn Gly Ser  Ser Ser Lys Ala Thr  Pro Ser Thr 
    1925                 1930                 1935             


Ala Lys  Glu Thr Ser 
    1940             


<210>  1212
<211>  1249
<212>  PRT
<213>  Human

<400>  1212

Met Val Glu Ala Ala Pro Pro Gly Pro Gly Pro Leu Arg Arg Thr Phe 
1               5                   10                  15      


Leu Val Pro Glu Ile Lys Ser Leu Asp Gln Tyr Asp Phe Ser Arg Ala 
            20                  25                  30          


Lys Ala Ala Ala Ser Leu Ala Trp Val Leu Arg Ala Ala Phe Gly Gly 
        35                  40                  45              


Ala Glu His Val Pro Pro Glu Leu Trp Glu Pro Phe Tyr Thr Asp Gln 
    50                  55                  60                  


Tyr Ala Gln Glu His Val Lys Pro Pro Val Thr Arg Leu Leu Leu Ser 
65                  70                  75                  80  


Ala Glu Leu Tyr Cys Arg Ala Trp Arg Gln Ala Leu Pro Gln Leu Glu 
                85                  90                  95      


Thr Pro Pro Asn Pro Ser Ala Leu Leu Ala Leu Leu Ala Arg Arg Gly 
            100                 105                 110         


Thr Val Pro Ala Leu Pro Glu Arg Pro Val Arg Glu Ala Asp Leu Arg 
        115                 120                 125             


His Gln Pro Ile Leu Met Gly Ala His Leu Ala Val Ile Asp Ala Leu 
    130                 135                 140                 


Met Ala Ala Phe Ala Phe Glu Trp Thr Lys Thr Leu Pro Gly Pro Leu 
145                 150                 155                 160 


Ala Leu Thr Ser Leu Glu His Lys Leu Leu Phe Trp Val Asp Thr Thr 
                165                 170                 175     


Val Arg Arg Leu Gln Glu Lys Thr Glu Gln Glu Ala Ala Gln Arg Ala 
            180                 185                 190         


Ser Pro Ala Ala Pro Ala Asp Gly Ala Ala Pro Ala Gln Pro Ser Ile 
        195                 200                 205             


Arg Tyr Arg Lys Asp Arg Val Val Ala Arg Arg Ala Pro Cys Phe Pro 
    210                 215                 220                 


Thr Val Thr Ser Leu Gln Asp Leu Ala Ser Gly Ala Ala Leu Ala Ala 
225                 230                 235                 240 


Thr Ile His Cys Tyr Cys Pro Gln Leu Leu Arg Leu Glu Glu Val Cys 
                245                 250                 255     


Leu Lys Asp Pro Met Ser Val Ala Asp Ser Leu Tyr Asn Leu Gln Leu 
            260                 265                 270         


Val Gln Asp Phe Cys Ala Ser Arg Leu Pro Arg Gly Cys Pro Leu Ser 
        275                 280                 285             


Leu Glu Asp Leu Leu Tyr Val Pro Pro Pro Leu Lys Val Asn Leu Val 
    290                 295                 300                 


Val Met Leu Ala Glu Leu Phe Met Cys Phe Glu Val Leu Lys Pro Asp 
305                 310                 315                 320 


Phe Val Gln Val Lys Asp Leu Pro Asp Gly His Ala Ala Ser Pro Arg 
                325                 330                 335     


Gly Thr Glu Ala Ser Pro Pro Gln Asn Asn Ser Gly Ser Ser Ser Pro 
            340                 345                 350         


Val Phe Thr Phe Arg His Pro Leu Leu Ser Ser Gly Gly Pro Gln Ser 
        355                 360                 365             


Pro Leu Arg Gly Ser Thr Gly Ser Leu Lys Ser Ser Pro Ser Met Ser 
    370                 375                 380                 


His Met Glu Ala Leu Gly Lys Ala Trp Asn Arg Gln Leu Ser Arg Pro 
385                 390                 395                 400 


Leu Ser Gln Ala Val Ser Phe Ser Thr Pro Phe Gly Leu Asp Ser Asp 
                405                 410                 415     


Val Asp Val Val Met Gly Asp Pro Val Leu Leu Arg Ser Val Ser Ser 
            420                 425                 430         


Asp Ser Leu Gly Pro Pro Arg Pro Ala Pro Ala Arg Thr Pro Thr Gln 
        435                 440                 445             


Pro Pro Pro Glu Pro Gly Asp Leu Pro Thr Ile Glu Glu Ala Leu Gln 
    450                 455                 460                 


Ile Ile His Ser Ala Glu Pro Arg Leu Leu Pro Asp Gly Ala Ala Asp 
465                 470                 475                 480 


Gly Ser Phe Tyr Leu His Ser Pro Glu Gly Pro Ser Lys Pro Ser Leu 
                485                 490                 495     


Ala Ser Pro Tyr Leu Pro Glu Gly Thr Ser Lys Pro Leu Ser Asp Arg 
            500                 505                 510         


Pro Thr Lys Ala Pro Val Tyr Met Pro His Pro Glu Thr Pro Ser Lys 
        515                 520                 525             


Pro Ser Pro Cys Leu Val Gly Glu Ala Ser Lys Pro Pro Ala Pro Ser 
    530                 535                 540                 


Glu Gly Ser Pro Lys Ala Val Ala Ser Ser Pro Ala Ala Thr Asn Ser 
545                 550                 555                 560 


Glu Val Lys Met Thr Ser Phe Ala Glu Arg Lys Lys Gln Leu Val Lys 
                565                 570                 575     


Ala Glu Ala Glu Ala Gly Ala Gly Ser Pro Thr Ser Thr Pro Ala Pro 
            580                 585                 590         


Pro Glu Ala Leu Ser Ser Glu Met Ser Glu Leu Ser Ala Arg Leu Glu 
        595                 600                 605             


Glu Lys Arg Arg Ala Ile Glu Ala Gln Lys Arg Arg Ile Glu Ala Ile 
    610                 615                 620                 


Phe Ala Lys His Arg Gln Arg Leu Gly Lys Ser Ala Phe Leu Gln Val 
625                 630                 635                 640 


Gln Pro Arg Glu Ala Ser Gly Glu Ala Glu Ala Glu Ala Glu Glu Ala 
                645                 650                 655     


Asp Ser Gly Pro Val Pro Gly Gly Glu Arg Pro Ala Gly Glu Gly Gln 
            660                 665                 670         


Gly Glu Pro Thr Ser Arg Pro Lys Ala Val Thr Phe Ser Pro Asp Leu 
        675                 680                 685             


Gly Pro Val Pro His Glu Gly Leu Gly Glu Tyr Asn Arg Ala Val Ser 
    690                 695                 700                 


Lys Leu Ser Ala Ala Leu Ser Ser Leu Gln Arg Asp Met Gln Arg Leu 
705                 710                 715                 720 


Thr Asp Gln Gln Gln Arg Leu Leu Ala Pro Pro Glu Ala Pro Gly Ser 
                725                 730                 735     


Ala Pro Pro Pro Ala Ala Trp Val Ile Pro Gly Pro Thr Thr Gly Pro 
            740                 745                 750         


Lys Ala Ala Ser Pro Ser Pro Ala Arg Arg Val Pro Ala Thr Arg Arg 
        755                 760                 765             


Ser Pro Gly Pro Gly Pro Ser Gln Ser Pro Arg Ser Pro Lys His Thr 
    770                 775                 780                 


Arg Pro Ala Glu Leu Arg Leu Ala Pro Leu Thr Arg Val Leu Thr Pro 
785                 790                 795                 800 


Pro His Asp Val Asp Ser Leu Pro His Leu Arg Lys Phe Ser Pro Ser 
                805                 810                 815     


Gln Val Pro Val Gln Thr Arg Ser Ser Ile Leu Leu Ala Glu Glu Thr 
            820                 825                 830         


Pro Pro Glu Glu Pro Ala Ala Arg Pro Gly Leu Ile Glu Ile Pro Leu 
        835                 840                 845             


Gly Ser Leu Ala Asp Pro Ala Ala Glu Asp Glu Gly Asp Gly Ser Pro 
    850                 855                 860                 


Ala Gly Ala Glu Asp Ser Leu Glu Glu Glu Ala Ser Ser Glu Gly Glu 
865                 870                 875                 880 


Pro Arg Val Gly Leu Gly Phe Phe Tyr Lys Asp Glu Asp Lys Pro Glu 
                885                 890                 895     


Asp Glu Met Ala Gln Lys Arg Ala Ser Leu Leu Glu Arg Gln Gln Arg 
            900                 905                 910         


Arg Ala Glu Glu Ala Arg Arg Arg Lys Gln Trp Gln Glu Val Glu Lys 
        915                 920                 925             


Glu Gln Arg Arg Glu Glu Ala Ala Arg Leu Ala Gln Glu Glu Ala Pro 
    930                 935                 940                 


Gly Pro Ala Pro Leu Val Ser Ala Val Pro Met Ala Thr Pro Ala Pro 
945                 950                 955                 960 


Ala Ala Arg Ala Pro Ala Glu Glu Glu Val Gly Pro Arg Lys Gly Asp 
                965                 970                 975     


Phe Thr Arg Gln Glu Tyr Glu Arg Arg Ala Gln Leu Lys Leu Met Asp 
            980                 985                 990         


Asp Leu Asp Lys Val Leu Arg Pro  Arg Ala Ala Gly Ser  Gly Gly Pro 
        995                 1000                 1005             


Gly Arg  Gly Gly Arg Arg Ala  Thr Arg Pro Arg Ser  Gly Cys Cys 
    1010                 1015                 1020             


Asp Asp  Ser Ala Leu Ala Arg  Ser Pro Ala Arg Gly  Leu Leu Gly 
    1025                 1030                 1035             


Ser Arg  Leu Ser Lys Ile Tyr  Ser Gln Ser Thr Leu  Ser Leu Ser 
    1040                 1045                 1050             


Thr Val  Ala Asn Glu Ala His  Asn Asn Leu Gly Val  Lys Arg Pro 
    1055                 1060                 1065             


Thr Ser  Arg Ala Pro Ser Pro  Ser Gly Leu Met Ser  Pro Ser Arg 
    1070                 1075                 1080             


Leu Pro  Gly Ser Arg Glu Arg  Asp Trp Glu Asn Gly  Ser Asn Ala 
    1085                 1090                 1095             


Ser Ser  Pro Ala Ser Val Pro  Glu Tyr Thr Gly Pro  Arg Leu Tyr 
    1100                 1105                 1110             


Lys Glu  Pro Ser Ala Lys Ser  Asn Lys Phe Ile Ile  His Asn Ala 
    1115                 1120                 1125             


Leu Ser  His Cys Cys Leu Ala  Gly Lys Val Asn Glu  Pro Gln Lys 
    1130                 1135                 1140             


Asn Arg  Ile Leu Glu Glu Ile  Glu Lys Ser Lys Ala  Asn His Phe 
    1145                 1150                 1155             


Leu Ile  Leu Phe Arg Asp Ser  Ser Cys Gln Phe Arg  Ala Leu Tyr 
    1160                 1165                 1170             


Thr Leu  Ser Gly Glu Thr Glu  Glu Leu Ser Arg Leu  Ala Gly Tyr 
    1175                 1180                 1185             


Gly Pro  Arg Thr Val Thr Pro  Ala Met Val Glu Gly  Ile Tyr Lys 
    1190                 1195                 1200             


Tyr Asn  Ser Asp Arg Lys Arg  Phe Thr Gln Ile Pro  Ala Lys Thr 
    1205                 1210                 1215             


Met Ser  Met Ser Val Asp Ala  Phe Thr Ile Gln Gly  His Leu Trp 
    1220                 1225                 1230             


Gln Gly  Lys Lys Pro Thr Thr  Pro Lys Lys Gly Gly  Gly Thr Pro 
    1235                 1240                 1245             


Lys 
    


<210>  1213
<211>  1771
<212>  PRT
<213>  Human

<400>  1213

Met Ser Val Leu Ile Ser Gln Ser Val Ile Asn Tyr Val Glu Glu Glu 
1               5                   10                  15      


Asn Ile Pro Ala Leu Lys Ala Leu Leu Glu Lys Cys Lys Asp Val Asp 
            20                  25                  30          


Glu Arg Asn Glu Cys Gly Gln Thr Pro Leu Met Ile Ala Ala Glu Gln 
        35                  40                  45              


Gly Asn Leu Glu Ile Val Lys Glu Leu Ile Lys Asn Gly Ala Asn Cys 
    50                  55                  60                  


Asn Leu Glu Asp Leu Asp Asn Trp Thr Ala Leu Ile Ser Ala Ser Lys 
65                  70                  75                  80  


Glu Gly His Val His Ile Val Glu Glu Leu Leu Lys Cys Gly Val Asn 
                85                  90                  95      


Leu Glu His Arg Asp Met Gly Gly Trp Thr Ala Leu Met Trp Ala Cys 
            100                 105                 110         


Tyr Lys Gly Arg Thr Asp Val Val Glu Leu Leu Leu Ser His Gly Ala 
        115                 120                 125             


Asn Pro Ser Val Thr Gly Leu Tyr Ser Val Tyr Pro Ile Ile Trp Ala 
    130                 135                 140                 


Ala Gly Arg Gly His Ala Asp Ile Val His Leu Leu Leu Gln Asn Gly 
145                 150                 155                 160 


Ala Lys Val Asn Cys Ser Asp Lys Tyr Gly Thr Thr Pro Leu Val Trp 
                165                 170                 175     


Ala Ala Arg Lys Gly His Leu Glu Cys Val Lys His Leu Leu Ala Met 
            180                 185                 190         


Gly Ala Asp Val Asp Gln Glu Gly Ala Asn Ser Met Thr Ala Leu Ile 
        195                 200                 205             


Val Ala Val Lys Gly Gly Tyr Thr Gln Ser Val Lys Glu Ile Leu Lys 
    210                 215                 220                 


Arg Asn Pro Asn Val Asn Leu Thr Asp Lys Asp Gly Asn Thr Ala Leu 
225                 230                 235                 240 


Met Ile Ala Ser Lys Glu Gly His Thr Glu Ile Val Gln Asp Leu Leu 
                245                 250                 255     


Asp Ala Gly Thr Tyr Val Asn Ile Pro Asp Arg Ser Gly Asp Thr Val 
            260                 265                 270         


Leu Ile Gly Ala Val Arg Gly Gly His Val Glu Ile Val Arg Ala Leu 
        275                 280                 285             


Leu Gln Lys Tyr Ala Asp Ile Asp Ile Arg Gly Gln Asp Asn Lys Thr 
    290                 295                 300                 


Ala Leu Tyr Trp Ala Val Glu Lys Gly Asn Ala Thr Met Val Arg Asp 
305                 310                 315                 320 


Ile Leu Gln Cys Asn Pro Asp Thr Glu Ile Cys Thr Lys Asp Gly Glu 
                325                 330                 335     


Thr Pro Leu Ile Lys Ala Thr Lys Met Arg Asn Ile Glu Val Val Glu 
            340                 345                 350         


Leu Leu Leu Asp Lys Gly Ala Lys Val Ser Ala Val Asp Lys Lys Gly 
        355                 360                 365             


Asp Thr Pro Leu His Ile Ala Ile Arg Gly Arg Ser Arg Lys Leu Ala 
    370                 375                 380                 


Glu Leu Leu Leu Arg Asn Pro Lys Asp Gly Arg Leu Leu Tyr Arg Pro 
385                 390                 395                 400 


Asn Lys Ala Gly Glu Thr Pro Tyr Asn Ile Asp Cys Ser His Gln Lys 
                405                 410                 415     


Ser Ile Leu Thr Gln Ile Phe Gly Ala Arg His Leu Ser Pro Thr Glu 
            420                 425                 430         


Thr Asp Gly Asp Met Leu Gly Tyr Asp Leu Tyr Ser Ser Ala Leu Ala 
        435                 440                 445             


Asp Ile Leu Ser Glu Pro Thr Met Gln Pro Pro Ile Cys Val Gly Leu 
    450                 455                 460                 


Tyr Ala Gln Trp Gly Ser Gly Lys Ser Phe Leu Leu Lys Lys Leu Glu 
465                 470                 475                 480 


Asp Glu Met Lys Thr Phe Ala Gly Gln Gln Ile Glu Pro Leu Phe Gln 
                485                 490                 495     


Phe Ser Trp Leu Ile Val Phe Leu Thr Leu Leu Leu Cys Gly Gly Leu 
            500                 505                 510         


Gly Leu Leu Phe Ala Phe Thr Val His Pro Asn Leu Gly Ile Ala Val 
        515                 520                 525             


Ser Leu Ser Phe Leu Ala Leu Leu Tyr Ile Phe Phe Ile Val Ile Tyr 
    530                 535                 540                 


Phe Gly Gly Arg Arg Glu Gly Glu Ser Trp Asn Trp Ala Trp Val Leu 
545                 550                 555                 560 


Ser Thr Arg Leu Ala Arg His Ile Gly Tyr Leu Glu Leu Leu Leu Lys 
                565                 570                 575     


Leu Met Phe Val Asn Pro Pro Glu Leu Pro Glu Gln Thr Thr Lys Ala 
            580                 585                 590         


Leu Pro Val Arg Phe Leu Phe Thr Asp Tyr Asn Arg Leu Ser Ser Val 
        595                 600                 605             


Gly Gly Glu Thr Ser Leu Ala Glu Met Ile Ala Thr Leu Ser Asp Ala 
    610                 615                 620                 


Cys Glu Arg Glu Phe Gly Phe Leu Ala Thr Arg Leu Phe Arg Val Phe 
625                 630                 635                 640 


Lys Thr Glu Asp Thr Gln Gly Lys Lys Lys Trp Lys Lys Thr Cys Cys 
                645                 650                 655     


Leu Pro Ser Phe Val Ile Phe Leu Phe Ile Ile Gly Cys Ile Ile Ser 
            660                 665                 670         


Gly Ile Thr Leu Leu Ala Ile Phe Arg Val Asp Pro Lys His Leu Thr 
        675                 680                 685             


Val Asn Ala Val Leu Ile Ser Ile Ala Ser Val Val Gly Leu Ala Phe 
    690                 695                 700                 


Val Leu Asn Cys Arg Thr Trp Trp Gln Val Leu Asp Ser Leu Leu Asn 
705                 710                 715                 720 


Ser Gln Arg Lys Arg Leu His Asn Ala Ala Ser Lys Leu His Lys Leu 
                725                 730                 735     


Lys Ser Glu Gly Phe Met Lys Val Leu Lys Cys Glu Val Glu Leu Met 
            740                 745                 750         


Ala Arg Met Ala Lys Thr Ile Asp Ser Phe Thr Gln Asn Gln Thr Arg 
        755                 760                 765             


Leu Val Val Ile Ile Asp Gly Leu Asp Ala Cys Glu Gln Asp Lys Val 
    770                 775                 780                 


Leu Gln Met Leu Asp Thr Val Arg Val Leu Phe Ser Lys Gly Pro Phe 
785                 790                 795                 800 


Ile Ala Ile Phe Ala Ser Asp Pro His Ile Ile Ile Lys Ala Ile Asn 
                805                 810                 815     


Gln Asn Leu Asn Ser Val Leu Arg Asp Ser Asn Ile Asn Gly His Asp 
            820                 825                 830         


Tyr Met Arg Asn Ile Val His Leu Pro Val Phe Leu Asn Ser Arg Gly 
        835                 840                 845             


Leu Ser Asn Ala Arg Lys Phe Leu Val Thr Ser Ala Thr Asn Gly Asp 
    850                 855                 860                 


Val Pro Cys Ser Asp Thr Thr Gly Ile Gln Glu Asp Ala Asp Arg Arg 
865                 870                 875                 880 


Val Ser Gln Asn Ser Leu Gly Glu Met Thr Lys Leu Gly Ser Lys Thr 
                885                 890                 895     


Ala Leu Asn Arg Arg Asp Thr Tyr Arg Arg Arg Gln Met Gln Arg Thr 
            900                 905                 910         


Ile Thr Arg Gln Met Ser Phe Asp Leu Thr Lys Leu Leu Val Thr Glu 
        915                 920                 925             


Asp Trp Phe Ser Asp Ile Ser Pro Gln Thr Met Arg Arg Leu Leu Asn 
    930                 935                 940                 


Ile Val Ser Val Thr Gly Arg Leu Leu Arg Ala Asn Gln Ile Ser Phe 
945                 950                 955                 960 


Asn Trp Asp Arg Leu Ala Ser Trp Ile Asn Leu Thr Glu Gln Trp Pro 
                965                 970                 975     


Tyr Arg Thr Ser Trp Leu Ile Leu Tyr Leu Glu Glu Thr Glu Gly Ile 
            980                 985                 990         


Pro Asp Gln Met Thr Leu Lys Thr  Ile Tyr Glu Arg Ile  Ser Lys Asn 
        995                 1000                 1005             


Ile Pro  Thr Thr Lys Asp Val  Glu Pro Leu Leu Glu  Ile Asp Gly 
    1010                 1015                 1020             


Asp Ile  Arg Asn Phe Glu Val  Phe Leu Ser Ser Arg  Thr Pro Val 
    1025                 1030                 1035             


Leu Val  Ala Arg Asp Val Lys  Val Phe Leu Pro Cys  Thr Val Asn 
    1040                 1045                 1050             


Leu Asp  Pro Lys Leu Arg Glu  Ile Ile Ala Asp Val  Arg Ala Ala 
    1055                 1060                 1065             


Arg Glu  Gln Ile Ser Ile Gly  Gly Leu Ala Tyr Pro  Pro Leu Pro 
    1070                 1075                 1080             


Leu His  Glu Gly Pro Pro Arg  Ala Pro Ser Gly Tyr  Ser Gln Pro 
    1085                 1090                 1095             


Pro Ser  Val Cys Ser Ser Thr  Ser Phe Asn Gly Pro  Phe Ala Gly 
    1100                 1105                 1110             


Gly Val  Val Ser Pro Gln Pro  His Ser Ser Tyr Tyr  Ser Gly Met 
    1115                 1120                 1125             


Thr Gly  Pro Gln His Pro Phe  Tyr Asn Arg Pro Phe  Phe Ala Pro 
    1130                 1135                 1140             


Tyr Leu  Tyr Thr Pro Arg Tyr  Tyr Pro Gly Gly Ser  Gln His Leu 
    1145                 1150                 1155             


Ile Ser  Arg Pro Ser Val Lys  Thr Ser Leu Pro Arg  Asp Gln Asn 
    1160                 1165                 1170             


Asn Gly  Leu Glu Val Ile Lys  Glu Asp Ala Ala Glu  Gly Leu Ser 
    1175                 1180                 1185             


Ser Pro  Thr Asp Ser Ser Arg  Gly Ser Gly Pro Ala  Pro Gly Pro 
    1190                 1195                 1200             


Val Val  Leu Leu Asn Ser Leu  Asn Val Asp Ala Val  Cys Glu Lys 
    1205                 1210                 1215             


Leu Lys  Gln Ile Glu Gly Leu  Asp Gln Ser Met Leu  Pro Gln Tyr 
    1220                 1225                 1230             


Cys Thr  Thr Ile Lys Lys Ala  Asn Ile Asn Gly Arg  Val Leu Ala 
    1235                 1240                 1245             


Gln Cys  Asn Ile Asp Glu Leu  Lys Lys Glu Met Asn  Met Asn Phe 
    1250                 1255                 1260             


Gly Asp  Trp His Leu Phe Arg  Ser Thr Val Leu Glu  Met Arg Asn 
    1265                 1270                 1275             


Ala Glu  Ser His Val Val Pro  Glu Asp Pro Arg Phe  Leu Ser Glu 
    1280                 1285                 1290             


Ser Ser  Ser Gly Pro Ala Pro  His Gly Glu Pro Ala  Arg Arg Ala 
    1295                 1300                 1305             


Ser His  Asn Glu Leu Pro His  Thr Glu Leu Ser Ser  Gln Thr Pro 
    1310                 1315                 1320             


Tyr Thr  Leu Asn Phe Ser Phe  Glu Glu Leu Asn Thr  Leu Gly Leu 
    1325                 1330                 1335             


Asp Glu  Gly Ala Pro Arg His  Ser Asn Leu Ser Trp  Gln Ser Gln 
    1340                 1345                 1350             


Thr Arg  Arg Thr Pro Ser Leu  Ser Ser Leu Asn Ser  Gln Asp Ser 
    1355                 1360                 1365             


Ser Ile  Glu Ile Ser Lys Leu  Thr Asp Lys Val Gln  Ala Glu Tyr 
    1370                 1375                 1380             


Arg Asp  Ala Tyr Arg Glu Tyr  Ile Ala Gln Met Ser  Gln Leu Glu 
    1385                 1390                 1395             


Gly Gly  Pro Gly Ser Thr Thr  Ile Ser Gly Arg Ser  Ser Pro His 
    1400                 1405                 1410             


Ser Thr  Tyr Tyr Met Gly Gln  Ser Ser Ser Gly Gly  Ser Ile His 
    1415                 1420                 1425             


Ser Asn  Leu Glu Gln Glu Lys  Gly Lys Asp Ser Glu  Pro Lys Pro 
    1430                 1435                 1440             


Asp Asp  Gly Arg Lys Ser Phe  Leu Met Lys Arg Gly  Asp Val Ile 
    1445                 1450                 1455             


Asp Tyr  Ser Ser Ser Gly Val  Ser Thr Asn Asp Ala  Ser Pro Leu 
    1460                 1465                 1470             


Asp Pro  Ile Thr Glu Glu Asp  Glu Lys Ser Asp Gln  Ser Gly Ser 
    1475                 1480                 1485             


Lys Leu  Leu Pro Gly Lys Lys  Ser Ser Glu Arg Ser  Ser Leu Phe 
    1490                 1495                 1500             


Gln Thr  Asp Leu Lys Leu Lys  Gly Ser Gly Leu Arg  Tyr Gln Lys 
    1505                 1510                 1515             


Leu Pro  Ser Asp Glu Asp Glu  Ser Gly Thr Glu Glu  Ser Asp Asn 
    1520                 1525                 1530             


Thr Pro  Leu Leu Lys Asp Asp  Lys Asp Arg Lys Ala  Glu Gly Lys 
    1535                 1540                 1545             


Val Glu  Arg Val Pro Lys Ser  Pro Glu His Ser Ala  Glu Pro Ile 
    1550                 1555                 1560             


Arg Thr  Phe Ile Lys Ala Lys  Glu Tyr Leu Ser Asp  Ala Leu Leu 
    1565                 1570                 1575             


Asp Lys  Lys Asp Ser Ser Asp  Ser Gly Val Arg Ser  Ser Glu Ser 
    1580                 1585                 1590             


Ser Pro  Asn His Ser Leu His  Asn Glu Val Ala Asp  Asp Ser Gln 
    1595                 1600                 1605             


Leu Glu  Lys Ala Asn Leu Ile  Glu Leu Glu Asp Asp  Ser His Ser 
    1610                 1615                 1620             


Gly Lys  Arg Gly Ile Pro His  Ser Leu Ser Gly Leu  Gln Asp Pro 
    1625                 1630                 1635             


Ile Ile  Ala Arg Met Ser Ile  Cys Ser Glu Asp Lys  Lys Ser Pro 
    1640                 1645                 1650             


Ser Glu  Cys Ser Leu Ile Ala  Ser Ser Pro Glu Glu  Asn Trp Pro 
    1655                 1660                 1665             


Ala Cys  Gln Lys Ala Tyr Asn  Leu Asn Arg Thr Pro  Ser Thr Val 
    1670                 1675                 1680             


Thr Leu  Asn Asn Asn Ser Ala  Pro Ala Asn Arg Ala  Asn Gln Asn 
    1685                 1690                 1695             


Phe Asp  Glu Met Glu Gly Ile  Arg Glu Thr Ser Gln  Val Ile Leu 
    1700                 1705                 1710             


Arg Pro  Ser Ser Ser Pro Asn  Pro Thr Thr Ile Gln  Asn Glu Asn 
    1715                 1720                 1725             


Leu Lys  Ser Met Thr His Lys  Arg Ser Gln Arg Ser  Ser Tyr Thr 
    1730                 1735                 1740             


Arg Leu  Ser Lys Asp Pro Pro  Glu Leu His Ala Ala  Ala Ser Ser 
    1745                 1750                 1755             


Glu Ser  Thr Gly Phe Gly Glu  Glu Arg Glu Ser Ile  Leu 
    1760                 1765                 1770     


<210>  1214
<211>  469
<212>  PRT
<213>  Human

<400>  1214

Met Ser Ile His Phe Ser Ser Pro Val Phe Thr Ser Arg Ser Ala Ala 
1               5                   10                  15      


Phe Ser Gly Arg Gly Ala Gln Val Arg Leu Ser Ser Ala Arg Pro Gly 
            20                  25                  30          


Gly Leu Gly Ser Ser Ser Leu Tyr Gly Leu Gly Ala Ser Arg Pro Arg 
        35                  40                  45              


Val Ala Val Arg Ser Ala Tyr Gly Gly Pro Val Gly Ala Gly Ile Arg 
    50                  55                  60                  


Glu Val Thr Ile Asn Gln Ser Leu Leu Ala Pro Leu Arg Leu Asp Ala 
65                  70                  75                  80  


Asp Pro Ser Leu Gln Arg Val Arg Gln Glu Glu Ser Glu Gln Ile Lys 
                85                  90                  95      


Thr Leu Asn Asn Lys Phe Ala Ser Phe Ile Asp Lys Val Arg Phe Leu 
            100                 105                 110         


Glu Gln Gln Asn Lys Leu Leu Glu Thr Lys Trp Thr Leu Leu Gln Glu 
        115                 120                 125             


Gln Lys Ser Ala Lys Ser Ser Arg Leu Pro Asp Ile Phe Glu Ala Gln 
    130                 135                 140                 


Ile Ala Gly Leu Arg Gly Gln Leu Glu Ala Leu Gln Val Asp Gly Gly 
145                 150                 155                 160 


Arg Leu Glu Ala Glu Leu Arg Ser Met Gln Asp Val Val Glu Asp Phe 
                165                 170                 175     


Lys Asn Lys Tyr Glu Asp Glu Ile Asn His Arg Thr Ala Ala Glu Asn 
            180                 185                 190         


Glu Phe Val Val Leu Lys Lys Asp Val Asp Ala Ala Tyr Met Ser Lys 
        195                 200                 205             


Val Glu Leu Glu Ala Lys Val Asp Ala Leu Asn Asp Glu Ile Asn Phe 
    210                 215                 220                 


Leu Arg Thr Leu Asn Glu Thr Glu Leu Thr Glu Leu Gln Ser Gln Ile 
225                 230                 235                 240 


Ser Asp Thr Ser Val Val Leu Ser Met Asp Asn Ser Arg Ser Leu Asp 
                245                 250                 255     


Leu Asp Gly Ile Ile Ala Glu Val Lys Ala Gln Tyr Glu Glu Met Ala 
            260                 265                 270         


Lys Cys Ser Arg Ala Glu Ala Glu Ala Trp Tyr Gln Thr Lys Phe Glu 
        275                 280                 285             


Thr Leu Gln Ala Gln Ala Gly Lys His Gly Asp Asp Leu Arg Asn Thr 
    290                 295                 300                 


Arg Asn Glu Ile Ser Glu Met Asn Arg Ala Ile Gln Arg Leu Gln Ala 
305                 310                 315                 320 


Glu Ile Asp Asn Ile Lys Asn Gln Arg Ala Lys Leu Glu Ala Ala Ile 
                325                 330                 335     


Ala Glu Ala Glu Glu Arg Gly Glu Leu Ala Leu Lys Asp Ala Arg Ala 
            340                 345                 350         


Lys Gln Glu Glu Leu Glu Ala Ala Leu Gln Arg Gly Lys Gln Asp Met 
        355                 360                 365             


Ala Arg Gln Leu Arg Glu Tyr Gln Glu Leu Met Ser Val Lys Leu Ala 
    370                 375                 380                 


Leu Asp Ile Glu Ile Ala Thr Tyr Arg Lys Leu Leu Glu Gly Glu Glu 
385                 390                 395                 400 


Ser Arg Leu Ala Gly Asp Gly Val Gly Ala Val Asn Ile Ser Val Met 
                405                 410                 415     


Asn Ser Thr Gly Gly Ser Ser Ser Gly Gly Gly Ile Gly Leu Thr Leu 
            420                 425                 430         


Gly Gly Thr Met Gly Ser Asn Ala Leu Ser Phe Ser Ser Ser Ala Gly 
        435                 440                 445             


Pro Gly Leu Leu Lys Ala Tyr Ser Ile Arg Thr Ala Ser Ala Ser Arg 
    450                 455                 460                 


Arg Ser Ala Arg Asp 
465                 


<210>  1215
<211>  128
<212>  PRT
<213>  Human

<400>  1215

Met Met Arg Phe Pro Leu Leu Ser His Lys Gln Gly Ser Lys Gly Gly 
1               5                   10                  15      


Pro Leu Cys Ser Gln Asn Ser Lys His Glu Thr Ile Ala Lys Gly Lys 
            20                  25                  30          


Thr Ala Lys Cys Phe Leu Ala Glu Phe Tyr Phe Ala Phe Ser Phe Cys 
        35                  40                  45              


His Phe Ser Ser Cys Tyr Arg Ala Leu Arg Cys Thr Glu Leu Gln Gln 
    50                  55                  60                  


Thr Gln Gly Ile Gln Gly Tyr Val Glu Lys Pro Leu Thr Thr Val Gln 
65                  70                  75                  80  


Gly Ala Glu Asp Ile Asn Asp Val Met Ser Thr Gln Pro Ala Leu Arg 
                85                  90                  95      


Ile Leu Gln Glu Lys Asn Thr Glu Ile Thr Pro Asp Arg Trp Tyr Phe 
            100                 105                 110         


Leu Lys Met Leu Tyr Cys Lys Arg Val Ala Arg Val Leu Gln Gly Leu 
        115                 120                 125             


<210>  1216
<211>  323
<212>  PRT
<213>  Human

<400>  1216

Met Ala Ala Glu Leu Ser Met Gly Pro Glu Leu Pro Thr Ser Pro Leu 
1               5                   10                  15      


Ala Met Glu Tyr Val Asn Asp Phe Asp Leu Leu Lys Phe Asp Val Lys 
            20                  25                  30          


Lys Glu Pro Leu Gly Arg Ala Glu Arg Pro Gly Arg Pro Cys Thr Arg 
        35                  40                  45              


Leu Gln Pro Ala Gly Ser Val Ser Ser Thr Pro Leu Ser Thr Pro Cys 
    50                  55                  60                  


Ser Ser Val Pro Ser Ser Pro Ser Phe Ser Pro Thr Glu Gln Lys Thr 
65                  70                  75                  80  


His Leu Glu Asp Leu Tyr Trp Met Ala Ser Asn Tyr Gln Gln Met Asn 
                85                  90                  95      


Pro Glu Ala Leu Asn Leu Thr Pro Glu Asp Ala Val Glu Ala Leu Ile 
            100                 105                 110         


Gly Ser His Pro Val Pro Gln Pro Leu Gln Ser Phe Asp Ser Phe Arg 
        115                 120                 125             


Gly Ala His His His His His His His His Pro His Pro His His Ala 
    130                 135                 140                 


Tyr Pro Gly Ala Gly Val Ala His Asp Glu Leu Gly Pro His Ala His 
145                 150                 155                 160 


Pro His His His His His His Gln Ala Ser Pro Pro Pro Ser Ser Ala 
                165                 170                 175     


Ala Ser Pro Ala Gln Gln Leu Pro Thr Ser His Pro Gly Pro Gly Pro 
            180                 185                 190         


His Ala Thr Ala Ser Ala Thr Ala Ala Gly Gly Asn Gly Ser Val Glu 
        195                 200                 205             


Asp Arg Phe Ser Asp Asp Gln Leu Val Ser Met Ser Val Arg Glu Leu 
    210                 215                 220                 


Asn Arg His Leu Arg Gly Phe Thr Lys Asp Glu Val Ile Arg Leu Lys 
225                 230                 235                 240 


Gln Lys Arg Arg Thr Leu Lys Asn Arg Gly Tyr Ala Gln Ser Cys Arg 
                245                 250                 255     


Tyr Lys Arg Val Gln Gln Lys His His Leu Glu Asn Glu Lys Thr Gln 
            260                 265                 270         


Leu Ile Gln Gln Val Glu Gln Leu Lys Gln Glu Val Ser Arg Leu Ala 
        275                 280                 285             


Arg Glu Arg Asp Ala Tyr Lys Val Lys Cys Glu Lys Leu Ala Asn Ser 
    290                 295                 300                 


Gly Phe Arg Glu Ala Gly Ser Thr Ser Asp Ser Pro Ser Ser Pro Glu 
305                 310                 315                 320 


Phe Phe Leu 
            


<210>  1217
<211>  135
<212>  PRT
<213>  Human

<400>  1217

Met Gly Leu Ser Val Arg Glu Leu Asn Arg His Leu Arg Gly Leu Ser 
1               5                   10                  15      


Ala Glu Glu Val Thr Arg Leu Lys Gln Arg Arg Arg Thr Leu Lys Asn 
            20                  25                  30          


Arg Gly Tyr Ala Ala Ser Cys Arg Val Lys Arg Val Cys Gln Lys Glu 
        35                  40                  45              


Glu Leu Gln Lys Gln Lys Ser Glu Leu Glu Arg Glu Val Asp Lys Leu 
    50                  55                  60                  


Ala Arg Glu Asn Ala Ala Met Arg Leu Glu Leu Asp Ala Leu Arg Gly 
65                  70                  75                  80  


Lys Cys Glu Ala Leu Gln Gly Phe Ala Arg Ser Val Ala Ala Ala Arg 
                85                  90                  95      


Gly Pro Ala Thr Leu Val Ala Pro Ala Ser Val Ile Thr Ile Val Lys 
            100                 105                 110         


Ser Thr Pro Gly Ser Gly Ser Gly Pro Ala His Gly Pro Asp Pro Ala 
        115                 120                 125             


His Gly Pro Ala Ser Cys Ser 
    130                 135 


<210>  1218
<211>  281
<212>  PRT
<213>  Human

<400>  1218

Met Ala Val Asn Val Tyr Ser Thr Ser Val Thr Ser Glu Asn Leu Ser 
1               5                   10                  15      


Arg His Asp Met Leu Ala Trp Val Asn Asp Ser Leu His Leu Asn Tyr 
            20                  25                  30          


Thr Lys Ile Glu Gln Leu Cys Ser Gly Ala Ala Tyr Cys Gln Phe Met 
        35                  40                  45              


Asp Met Leu Phe Pro Gly Cys Val His Leu Arg Lys Val Lys Phe Gln 
    50                  55                  60                  


Ala Lys Leu Glu His Glu Tyr Ile His Asn Phe Lys Val Leu Gln Ala 
65                  70                  75                  80  


Ala Phe Lys Lys Met Gly Val Asp Lys Ile Ile Pro Val Glu Lys Leu 
                85                  90                  95      


Val Lys Gly Lys Phe Gln Asp Asn Phe Glu Phe Ile Gln Trp Phe Lys 
            100                 105                 110         


Lys Phe Phe Asp Ala Asn Tyr Asp Gly Lys Asp Tyr Asn Pro Leu Leu 
        115                 120                 125             


Ala Arg Gln Gly Gln Asp Val Ala Pro Pro Pro Asn Pro Gly Asp Gln 
    130                 135                 140                 


Ile Phe Asn Lys Ser Lys Lys Leu Ile Gly Thr Ala Val Pro Gln Arg 
145                 150                 155                 160 


Thr Ser Pro Thr Gly Pro Lys Asn Met Gln Thr Ser Gly Arg Leu Ser 
                165                 170                 175     


Asn Val Ala Pro Pro Cys Ile Leu Arg Lys Asn Pro Pro Ser Ala Arg 
            180                 185                 190         


Asn Gly Gly His Glu Thr Asp Ala Gln Ile Leu Glu Leu Asn Gln Gln 
        195                 200                 205             


Leu Val Asp Leu Lys Leu Thr Val Asp Gly Leu Glu Lys Glu Arg Asp 
    210                 215                 220                 


Phe Tyr Phe Ser Lys Leu Arg Asp Ile Glu Leu Ile Cys Gln Glu His 
225                 230                 235                 240 


Glu Ser Glu Asn Ser Pro Val Ile Ser Gly Ile Ile Gly Ile Leu Tyr 
                245                 250                 255     


Ala Thr Glu Glu Gly Phe Ala Pro Pro Glu Asp Asp Glu Ile Glu Glu 
            260                 265                 270         


His Gln Gln Glu Asp Gln Asp Glu Tyr 
        275                 280     


<210>  1219
<211>  248
<212>  PRT
<213>  Human

<400>  1219

Met Phe Arg Phe Met Arg Asp Val Glu Pro Glu Asp Pro Met Phe Leu 
1               5                   10                  15      


Met Asp Pro Phe Ala Ile His Arg Gln His Met Ser Arg Met Leu Ser 
            20                  25                  30          


Gly Gly Phe Gly Tyr Ser Pro Phe Leu Ser Ile Thr Asp Gly Asn Met 
        35                  40                  45              


Pro Gly Thr Arg Pro Ala Ser Arg Arg Met Gln Gln Ala Gly Ala Val 
    50                  55                  60                  


Ser Pro Phe Gly Met Leu Gly Met Ser Gly Gly Phe Met Asp Met Phe 
65                  70                  75                  80  


Gly Met Met Asn Asp Met Ile Gly Asn Met Glu His Met Thr Ala Gly 
                85                  90                  95      


Gly Asn Cys Gln Thr Phe Ser Ser Ser Thr Val Ile Ser Tyr Ser Asn 
            100                 105                 110         


Thr Gly Asp Gly Ala Pro Lys Val Tyr Gln Glu Thr Ser Glu Met Arg 
        115                 120                 125             


Ser Ala Pro Gly Gly Ile Arg Glu Thr Arg Arg Thr Val Arg Asp Ser 
    130                 135                 140                 


Asp Ser Gly Leu Glu Gln Met Ser Ile Gly His His Ile Arg Asp Arg 
145                 150                 155                 160 


Ala His Ile Leu Gln Arg Ser Arg Asn His Arg Thr Gly Asp Gln Glu 
                165                 170                 175     


Glu Arg Gln Asp Tyr Ile Asn Leu Asp Glu Ser Glu Ala Ala Ala Phe 
            180                 185                 190         


Asp Asp Glu Trp Arg Arg Glu Thr Ser Arg Phe Arg Gln Gln Arg Pro 
        195                 200                 205             


Leu Glu Phe Arg Arg Leu Glu Ser Ser Gly Ala Gly Gly Arg Arg Ala 
    210                 215                 220                 


Glu Gly Pro Pro Arg Leu Ala Ile Gln Gly Pro Glu Asp Ser Pro Ser 
225                 230                 235                 240 


Arg Gln Ser Arg Arg Tyr Asp Trp 
                245             


<210>  1220
<211>  375
<212>  PRT
<213>  Human

<400>  1220

Met Ala Asp His Ser Phe Ser Asp Gly Val Pro Ser Asp Ser Val Glu 
1               5                   10                  15      


Ala Ala Lys Asn Ala Ser Asn Thr Glu Lys Leu Thr Asp Gln Val Met 
            20                  25                  30          


Gln Asn Pro Arg Val Leu Ala Ala Leu Gln Glu Arg Leu Asp Asn Val 
        35                  40                  45              


Pro His Thr Pro Ser Ser Tyr Ile Glu Thr Leu Pro Lys Ala Val Lys 
    50                  55                  60                  


Arg Arg Ile Asn Ala Leu Lys Gln Leu Gln Val Arg Cys Ala His Ile 
65                  70                  75                  80  


Glu Ala Lys Phe Tyr Glu Glu Val His Asp Leu Glu Arg Lys Tyr Ala 
                85                  90                  95      


Ala Leu Tyr Gln Pro Leu Phe Asp Lys Arg Arg Glu Phe Ile Thr Gly 
            100                 105                 110         


Asp Val Glu Pro Thr Asp Ala Glu Ser Glu Trp His Ser Glu Asn Glu 
        115                 120                 125             


Glu Glu Glu Lys Leu Ala Gly Asp Met Lys Ser Lys Val Val Val Thr 
    130                 135                 140                 


Glu Lys Ala Ala Ala Thr Ala Glu Glu Pro Asp Pro Lys Gly Ile Pro 
145                 150                 155                 160 


Glu Phe Trp Phe Thr Ile Phe Arg Asn Val Asp Met Leu Ser Glu Leu 
                165                 170                 175     


Val Gln Glu Tyr Asp Glu Pro Ile Leu Lys His Leu Gln Asp Ile Lys 
            180                 185                 190         


Val Lys Phe Ser Asp Pro Gly Gln Pro Met Ser Phe Val Leu Glu Phe 
        195                 200                 205             


His Phe Glu Pro Asn Asp Tyr Phe Thr Asn Ser Val Leu Thr Lys Thr 
    210                 215                 220                 


Tyr Lys Met Lys Ser Glu Pro Asp Lys Ala Asp Pro Phe Ser Phe Glu 
225                 230                 235                 240 


Gly Pro Glu Ile Val Asp Cys Asp Gly Cys Thr Ile Asp Trp Lys Lys 
                245                 250                 255     


Gly Lys Asn Val Thr Val Lys Thr Ile Lys Lys Lys Gln Lys His Lys 
            260                 265                 270         


Gly Arg Gly Thr Val Arg Thr Ile Thr Lys Gln Val Pro Asn Glu Ser 
        275                 280                 285             


Phe Phe Asn Phe Phe Asn Pro Leu Lys Ala Ser Gly Asp Gly Glu Ser 
    290                 295                 300                 


Leu Asp Glu Asp Ser Glu Phe Thr Leu Ala Ser Asp Phe Glu Ile Gly 
305                 310                 315                 320 


His Phe Phe Arg Glu Arg Ile Val Pro Arg Ala Val Leu Tyr Phe Thr 
                325                 330                 335     


Gly Glu Ala Ile Glu Asp Asp Asp Asn Phe Glu Glu Gly Glu Glu Gly 
            340                 345                 350         


Glu Glu Glu Glu Leu Glu Gly Asp Glu Glu Gly Glu Asp Glu Asp Asp 
        355                 360                 365             


Ala Glu Ile Asn Pro Lys Val 
    370                 375 


<210>  1221
<211>  526
<212>  PRT
<213>  Human

<400>  1221

Met Ser Leu Val Glu Ala Ile Ser Leu Trp Asn Glu Gly Val Leu Ala 
1               5                   10                  15      


Ala Asp Lys Lys Asp Trp Lys Gly Ala Leu Asp Ala Phe Ser Ala Val 
            20                  25                  30          


Gln Asp Pro His Ser Arg Ile Cys Phe Asn Ile Gly Cys Met Tyr Thr 
        35                  40                  45              


Ile Leu Lys Asn Met Thr Glu Ala Glu Lys Ala Phe Thr Arg Ser Ile 
    50                  55                  60                  


Asn Arg Asp Lys His Leu Ala Val Ala Tyr Phe Gln Arg Gly Met Leu 
65                  70                  75                  80  


Tyr Tyr Gln Thr Glu Lys Tyr Asp Leu Ala Ile Lys Asp Leu Lys Glu 
                85                  90                  95      


Ala Leu Ile Gln Leu Arg Gly Asn Gln Leu Ile Asp Tyr Lys Ile Leu 
            100                 105                 110         


Gly Leu Gln Phe Lys Leu Phe Ala Cys Glu Val Leu Tyr Asn Ile Ala 
        115                 120                 125             


Phe Met Tyr Ala Lys Lys Glu Glu Trp Lys Lys Ala Glu Glu Gln Leu 
    130                 135                 140                 


Ala Leu Ala Thr Ser Met Lys Ser Glu Pro Arg His Ser Lys Ile Asp 
145                 150                 155                 160 


Lys Ala Met Glu Cys Val Trp Lys Gln Lys Leu Tyr Glu Pro Val Val 
                165                 170                 175     


Ile Pro Val Gly Lys Leu Phe Arg Pro Asn Glu Arg Gln Val Ala Gln 
            180                 185                 190         


Leu Ala Lys Lys Asp Tyr Leu Gly Lys Ala Thr Val Val Ala Ser Val 
        195                 200                 205             


Val Asp Gln Asp Ser Phe Ser Gly Phe Ala Pro Leu Gln Pro Gln Ala 
    210                 215                 220                 


Ala Glu Pro Pro Pro Arg Pro Lys Thr Pro Glu Ile Phe Arg Ala Leu 
225                 230                 235                 240 


Glu Gly Glu Ala His Arg Val Leu Phe Gly Phe Val Pro Glu Thr Lys 
                245                 250                 255     


Glu Glu Leu Gln Val Met Pro Gly Asn Ile Val Phe Val Leu Lys Lys 
            260                 265                 270         


Gly Asn Asp Asn Trp Ala Thr Val Met Phe Asn Gly Gln Lys Gly Leu 
        275                 280                 285             


Val Pro Cys Asn Tyr Leu Glu Pro Val Glu Leu Arg Ile His Pro Gln 
    290                 295                 300                 


Gln Gln Pro Gln Glu Glu Ser Ser Pro Gln Ser Asp Ile Pro Ala Pro 
305                 310                 315                 320 


Pro Ser Ser Lys Ala Pro Gly Arg Pro Gln Leu Ser Pro Gly Gln Lys 
                325                 330                 335     


Gln Lys Glu Glu Pro Lys Glu Val Lys Leu Ser Val Pro Met Pro Tyr 
            340                 345                 350         


Thr Leu Lys Val His Tyr Lys Tyr Thr Val Val Met Lys Thr Gln Pro 
        355                 360                 365             


Gly Leu Pro Tyr Ser Gln Val Arg Asp Met Val Ser Lys Lys Leu Glu 
    370                 375                 380                 


Leu Arg Leu Glu His Thr Lys Leu Ser Tyr Arg Pro Arg Asp Ser Asn 
385                 390                 395                 400 


Glu Leu Val Pro Leu Ser Glu Asp Ser Met Lys Asp Ala Trp Gly Gln 
                405                 410                 415     


Val Lys Asn Tyr Cys Leu Thr Leu Trp Cys Glu Asn Thr Val Gly Asp 
            420                 425                 430         


Gln Gly Phe Pro Asp Glu Pro Lys Glu Ser Glu Lys Ala Asp Ala Asn 
        435                 440                 445             


Asn Gln Thr Thr Glu Pro Gln Leu Lys Lys Gly Ser Gln Val Glu Ala 
    450                 455                 460                 


Leu Phe Ser Tyr Glu Ala Thr Gln Pro Glu Asp Leu Glu Phe Gln Glu 
465                 470                 475                 480 


Gly Asp Ile Ile Leu Val Leu Ser Lys Val Asn Glu Glu Trp Leu Glu 
                485                 490                 495     


Gly Glu Cys Lys Gly Lys Val Gly Ile Phe Pro Lys Val Phe Val Glu 
            500                 505                 510         


Asp Cys Ala Thr Thr Asp Leu Glu Ser Thr Arg Arg Glu Val 
        515                 520                 525     


<210>  1222
<211>  605
<212>  PRT
<213>  Human

<400>  1222

Met Met Asp Leu Glu Leu Pro Pro Pro Gly Leu Pro Ser Gln Gln Asp 
1               5                   10                  15      


Met Asp Leu Ile Asp Ile Leu Trp Arg Gln Asp Ile Asp Leu Gly Val 
            20                  25                  30          


Ser Arg Glu Val Phe Asp Phe Ser Gln Arg Arg Lys Glu Tyr Glu Leu 
        35                  40                  45              


Glu Lys Gln Lys Lys Leu Glu Lys Glu Arg Gln Glu Gln Leu Gln Lys 
    50                  55                  60                  


Glu Gln Glu Lys Ala Phe Phe Ala Gln Leu Gln Leu Asp Glu Glu Thr 
65                  70                  75                  80  


Gly Glu Phe Leu Pro Ile Gln Pro Ala Gln His Ile Gln Ser Glu Thr 
                85                  90                  95      


Ser Gly Ser Ala Asn Tyr Ser Gln Val Ala His Ile Pro Lys Ser Asp 
            100                 105                 110         


Ala Leu Tyr Phe Asp Asp Cys Met Gln Leu Leu Ala Gln Thr Phe Pro 
        115                 120                 125             


Phe Val Asp Asp Asn Glu Val Ser Ser Ala Thr Phe Gln Ser Leu Val 
    130                 135                 140                 


Pro Asp Ile Pro Gly His Ile Glu Ser Pro Val Phe Ile Ala Thr Asn 
145                 150                 155                 160 


Gln Ala Gln Ser Pro Glu Thr Ser Val Ala Gln Val Ala Pro Val Asp 
                165                 170                 175     


Leu Asp Gly Met Gln Gln Asp Ile Glu Gln Val Trp Glu Glu Leu Leu 
            180                 185                 190         


Ser Ile Pro Glu Leu Gln Cys Leu Asn Ile Glu Asn Asp Lys Leu Val 
        195                 200                 205             


Glu Thr Thr Met Val Pro Ser Pro Glu Ala Lys Leu Thr Glu Val Asp 
    210                 215                 220                 


Asn Tyr His Phe Tyr Ser Ser Ile Pro Ser Met Glu Lys Glu Val Gly 
225                 230                 235                 240 


Asn Cys Ser Pro His Phe Leu Asn Ala Phe Glu Asp Ser Phe Ser Ser 
                245                 250                 255     


Ile Leu Ser Thr Glu Asp Pro Asn Gln Leu Thr Val Asn Ser Leu Asn 
            260                 265                 270         


Ser Asp Ala Thr Val Asn Thr Asp Phe Gly Asp Glu Phe Tyr Ser Ala 
        275                 280                 285             


Phe Ile Ala Glu Pro Ser Ile Ser Asn Ser Met Pro Ser Pro Ala Thr 
    290                 295                 300                 


Leu Ser His Ser Leu Ser Glu Leu Leu Asn Gly Pro Ile Asp Val Ser 
305                 310                 315                 320 


Asp Leu Ser Leu Cys Lys Ala Phe Asn Gln Asn His Pro Glu Ser Thr 
                325                 330                 335     


Ala Glu Phe Asn Asp Ser Asp Ser Gly Ile Ser Leu Asn Thr Ser Pro 
            340                 345                 350         


Ser Val Ala Ser Pro Glu His Ser Val Glu Ser Ser Ser Tyr Gly Asp 
        355                 360                 365             


Thr Leu Leu Gly Leu Ser Asp Ser Glu Val Glu Glu Leu Asp Ser Ala 
    370                 375                 380                 


Pro Gly Ser Val Lys Gln Asn Gly Pro Lys Thr Pro Val His Ser Ser 
385                 390                 395                 400 


Gly Asp Met Val Gln Pro Leu Ser Pro Ser Gln Gly Gln Ser Thr His 
                405                 410                 415     


Val His Asp Ala Gln Cys Glu Asn Thr Pro Glu Lys Glu Leu Pro Val 
            420                 425                 430         


Ser Pro Gly His Arg Lys Thr Pro Phe Thr Lys Asp Lys His Ser Ser 
        435                 440                 445             


Arg Leu Glu Ala His Leu Thr Arg Asp Glu Leu Arg Ala Lys Ala Leu 
    450                 455                 460                 


His Ile Pro Phe Pro Val Glu Lys Ile Ile Asn Leu Pro Val Val Asp 
465                 470                 475                 480 


Phe Asn Glu Met Met Ser Lys Glu Gln Phe Asn Glu Ala Gln Leu Ala 
                485                 490                 495     


Leu Ile Arg Asp Ile Arg Arg Arg Gly Lys Asn Lys Val Ala Ala Gln 
            500                 505                 510         


Asn Cys Arg Lys Arg Lys Leu Glu Asn Ile Val Glu Leu Glu Gln Asp 
        515                 520                 525             


Leu Asp His Leu Lys Asp Glu Lys Glu Lys Leu Leu Lys Glu Lys Gly 
    530                 535                 540                 


Glu Asn Asp Lys Ser Leu His Leu Leu Lys Lys Gln Leu Ser Thr Leu 
545                 550                 555                 560 


Tyr Leu Glu Val Phe Ser Met Leu Arg Asp Glu Asp Gly Lys Pro Tyr 
                565                 570                 575     


Ser Pro Ser Glu Tyr Ser Leu Gln Gln Thr Arg Asp Gly Asn Val Phe 
            580                 585                 590         


Leu Val Pro Lys Ser Lys Lys Pro Asp Val Lys Lys Asn 
        595                 600                 605 


<210>  1223
<211>  299
<212>  PRT
<213>  Human

<400>  1223

Met Glu Glu Leu Glu Gln Gly Leu Leu Met Gln Pro Trp Ala Trp Leu 
1               5                   10                  15      


Gln Leu Ala Glu Asn Ser Leu Leu Ala Lys Val Phe Ile Thr Lys Gln 
            20                  25                  30          


Gly Tyr Ala Leu Leu Val Ser Asp Leu Gln Gln Val Trp His Glu Gln 
        35                  40                  45              


Val Asp Thr Ser Val Val Ser Gln Arg Ala Lys Glu Leu Asn Lys Arg 
    50                  55                  60                  


Leu Thr Ala Pro Pro Ala Ala Phe Leu Cys His Leu Asp Asn Leu Leu 
65                  70                  75                  80  


Arg Pro Leu Leu Lys Asp Ala Ala His Pro Ser Glu Ala Thr Phe Ser 
                85                  90                  95      


Cys Asp Cys Val Ala Asp Ala Leu Ile Leu Arg Val Arg Ser Glu Leu 
            100                 105                 110         


Ser Gly Leu Pro Phe Tyr Trp Asn Phe His Cys Met Leu Ala Ser Pro 
        115                 120                 125             


Ser Leu Val Ser Gln His Leu Ile Arg Pro Leu Met Gly Met Ser Leu 
    130                 135                 140                 


Ala Leu Gln Cys Gln Val Arg Glu Leu Ala Thr Leu Leu His Met Lys 
145                 150                 155                 160 


Asp Leu Glu Ile Gln Asp Tyr Gln Glu Ser Gly Ala Thr Leu Ile Arg 
                165                 170                 175     


Asp Arg Leu Lys Thr Glu Pro Phe Glu Glu Asn Ser Phe Leu Glu Gln 
            180                 185                 190         


Phe Met Ile Glu Lys Leu Pro Glu Ala Cys Ser Ile Gly Asp Gly Lys 
        195                 200                 205             


Pro Phe Val Met Asn Leu Gln Asp Leu Tyr Met Ala Val Thr Thr Gln 
    210                 215                 220                 


Glu Val Gln Val Gly Gln Lys His Gln Gly Ala Gly Asp Pro His Thr 
225                 230                 235                 240 


Ser Asn Ser Ala Ser Leu Gln Gly Ile Asp Ser Gln Cys Val Asn Gln 
                245                 250                 255     


Pro Glu Gln Leu Val Ser Ser Ala Pro Thr Leu Ser Ala Pro Glu Lys 
            260                 265                 270         


Glu Ser Thr Gly Thr Ser Gly Pro Leu Gln Arg Pro Gln Leu Ser Lys 
        275                 280                 285             


Val Lys Arg Lys Lys Pro Arg Gly Leu Phe Ser 
    290                 295                 


<210>  1224
<211>  1375
<212>  PRT
<213>  Human

<400>  1224

Met Ala Gly Gly Ala Trp Gly Arg Leu Ala Cys Tyr Leu Glu Phe Leu 
1               5                   10                  15      


Lys Lys Glu Glu Leu Lys Glu Phe Gln Leu Leu Leu Ala Asn Lys Ala 
            20                  25                  30          


His Ser Arg Ser Ser Ser Gly Glu Thr Pro Ala Gln Pro Glu Lys Thr 
        35                  40                  45              


Ser Gly Met Glu Val Ala Ser Tyr Leu Val Ala Gln Tyr Gly Glu Gln 
    50                  55                  60                  


Arg Ala Trp Asp Leu Ala Leu His Thr Trp Glu Gln Met Gly Leu Arg 
65                  70                  75                  80  


Ser Leu Cys Ala Gln Ala Gln Glu Gly Ala Gly His Ser Pro Ser Phe 
                85                  90                  95      


Pro Tyr Ser Pro Ser Glu Pro His Leu Gly Ser Pro Ser Gln Pro Thr 
            100                 105                 110         


Ser Thr Ala Val Leu Met Pro Trp Ile His Glu Leu Pro Ala Gly Cys 
        115                 120                 125             


Thr Gln Gly Ser Glu Arg Arg Val Leu Arg Gln Leu Pro Asp Thr Ser 
    130                 135                 140                 


Gly Arg Arg Trp Arg Glu Ile Ser Ala Ser Leu Leu Tyr Gln Ala Leu 
145                 150                 155                 160 


Pro Ser Ser Pro Asp His Glu Ser Pro Ser Gln Glu Ser Pro Asn Ala 
                165                 170                 175     


Pro Thr Ser Thr Ala Val Leu Gly Ser Trp Gly Ser Pro Pro Gln Pro 
            180                 185                 190         


Ser Leu Ala Pro Arg Glu Gln Glu Ala Pro Gly Thr Gln Trp Pro Leu 
        195                 200                 205             


Asp Glu Thr Ser Gly Ile Tyr Tyr Thr Glu Ile Arg Glu Arg Glu Arg 
    210                 215                 220                 


Glu Lys Ser Glu Lys Gly Arg Pro Pro Trp Ala Ala Val Val Gly Thr 
225                 230                 235                 240 


Pro Pro Gln Ala His Thr Ser Leu Gln Pro His His His Pro Trp Glu 
                245                 250                 255     


Pro Ser Val Arg Glu Ser Leu Cys Ser Thr Trp Pro Trp Lys Asn Glu 
            260                 265                 270         


Asp Phe Asn Gln Lys Phe Thr Gln Leu Leu Leu Leu Gln Arg Pro His 
        275                 280                 285             


Pro Arg Ser Gln Asp Pro Leu Val Lys Arg Ser Trp Pro Asp Tyr Val 
    290                 295                 300                 


Glu Glu Asn Arg Gly His Leu Ile Glu Ile Arg Asp Leu Phe Gly Pro 
305                 310                 315                 320 


Gly Leu Asp Thr Gln Glu Pro Arg Ile Val Ile Leu Gln Gly Ala Ala 
                325                 330                 335     


Gly Ile Gly Lys Ser Thr Leu Ala Arg Gln Val Lys Glu Ala Trp Gly 
            340                 345                 350         


Arg Gly Gln Leu Tyr Gly Asp Arg Phe Gln His Val Phe Tyr Phe Ser 
        355                 360                 365             


Cys Arg Glu Leu Ala Gln Ser Lys Val Val Ser Leu Ala Glu Leu Ile 
    370                 375                 380                 


Gly Lys Asp Gly Thr Ala Thr Pro Ala Pro Ile Arg Gln Ile Leu Ser 
385                 390                 395                 400 


Arg Pro Glu Arg Leu Leu Phe Ile Leu Asp Gly Val Asp Glu Pro Gly 
                405                 410                 415     


Trp Val Leu Gln Glu Pro Ser Ser Glu Leu Cys Leu His Trp Ser Gln 
            420                 425                 430         


Pro Gln Pro Ala Asp Ala Leu Leu Gly Ser Leu Leu Gly Lys Thr Ile 
        435                 440                 445             


Leu Pro Glu Ala Ser Phe Leu Ile Thr Ala Arg Thr Thr Ala Leu Gln 
    450                 455                 460                 


Asn Leu Ile Pro Ser Leu Glu Gln Ala Arg Trp Val Glu Val Leu Gly 
465                 470                 475                 480 


Phe Ser Glu Ser Ser Arg Lys Glu Tyr Phe Tyr Arg Tyr Phe Thr Asp 
                485                 490                 495     


Glu Arg Gln Ala Ile Arg Ala Phe Arg Leu Val Lys Ser Asn Lys Glu 
            500                 505                 510         


Leu Trp Ala Leu Cys Leu Val Pro Trp Val Ser Trp Leu Ala Cys Thr 
        515                 520                 525             


Cys Leu Met Gln Gln Met Lys Arg Lys Glu Lys Leu Thr Leu Thr Ser 
    530                 535                 540                 


Lys Thr Thr Thr Thr Leu Cys Leu His Tyr Leu Ala Gln Ala Leu Gln 
545                 550                 555                 560 


Ala Gln Pro Leu Gly Pro Gln Leu Arg Asp Leu Cys Ser Leu Ala Ala 
                565                 570                 575     


Glu Gly Ile Trp Gln Lys Lys Thr Leu Phe Ser Pro Asp Asp Leu Arg 
            580                 585                 590         


Lys His Gly Leu Asp Gly Ala Ile Ile Ser Thr Phe Leu Lys Met Gly 
        595                 600                 605             


Ile Leu Gln Glu His Pro Ile Pro Leu Ser Tyr Ser Phe Ile His Leu 
    610                 615                 620                 


Cys Phe Gln Glu Phe Phe Ala Ala Met Ser Tyr Val Leu Glu Asp Glu 
625                 630                 635                 640 


Lys Gly Arg Gly Lys His Ser Asn Cys Ile Ile Asp Leu Glu Lys Thr 
                645                 650                 655     


Leu Glu Ala Tyr Gly Ile His Gly Leu Phe Gly Ala Ser Thr Thr Arg 
            660                 665                 670         


Phe Leu Leu Gly Leu Leu Ser Asp Glu Gly Glu Arg Glu Met Glu Asn 
        675                 680                 685             


Ile Phe His Cys Arg Leu Ser Gln Gly Arg Asn Leu Met Gln Trp Val 
    690                 695                 700                 


Pro Ser Leu Gln Leu Leu Leu Gln Pro His Ser Leu Glu Ser Leu His 
705                 710                 715                 720 


Cys Leu Tyr Glu Thr Arg Asn Lys Thr Phe Leu Thr Gln Val Met Ala 
                725                 730                 735     


His Phe Glu Glu Met Gly Met Cys Val Glu Thr Asp Met Glu Leu Leu 
            740                 745                 750         


Val Cys Thr Phe Cys Ile Lys Phe Ser Arg His Val Lys Lys Leu Gln 
        755                 760                 765             


Leu Ile Glu Gly Arg Gln His Arg Ser Thr Trp Ser Pro Thr Met Val 
    770                 775                 780                 


Val Leu Phe Arg Trp Val Pro Val Thr Asp Ala Tyr Trp Gln Ile Leu 
785                 790                 795                 800 


Phe Ser Val Leu Lys Val Thr Arg Asn Leu Lys Glu Leu Asp Leu Ser 
                805                 810                 815     


Gly Asn Ser Leu Ser His Ser Ala Val Lys Ser Leu Cys Lys Thr Leu 
            820                 825                 830         


Arg Arg Pro Arg Cys Leu Leu Glu Thr Leu Arg Leu Ala Gly Cys Gly 
        835                 840                 845             


Leu Thr Ala Glu Asp Cys Lys Asp Leu Ala Phe Gly Leu Arg Ala Asn 
    850                 855                 860                 


Gln Thr Leu Thr Glu Leu Asp Leu Ser Phe Asn Val Leu Thr Asp Ala 
865                 870                 875                 880 


Gly Ala Lys His Leu Cys Gln Arg Leu Arg Gln Pro Ser Cys Lys Leu 
                885                 890                 895     


Gln Arg Leu Gln Leu Val Ser Cys Gly Leu Thr Ser Asp Cys Cys Gln 
            900                 905                 910         


Asp Leu Ala Ser Val Leu Ser Ala Ser Pro Ser Leu Lys Glu Leu Asp 
        915                 920                 925             


Leu Gln Gln Asn Asn Leu Asp Asp Val Gly Val Arg Leu Leu Cys Glu 
    930                 935                 940                 


Gly Leu Arg His Pro Ala Cys Lys Leu Ile Arg Leu Gly Leu Asp Gln 
945                 950                 955                 960 


Thr Thr Leu Ser Asp Glu Met Arg Gln Glu Leu Arg Ala Leu Glu Gln 
                965                 970                 975     


Glu Lys Pro Gln Leu Leu Ile Phe Ser Arg Arg Lys Pro Ser Val Met 
            980                 985                 990         


Thr Pro Thr Glu Gly Leu Asp Thr  Gly Glu Met Ser Asn  Ser Thr Ser 
        995                 1000                 1005             


Ser Leu  Lys Arg Gln Arg Leu  Gly Ser Glu Arg Ala  Ala Ser His 
    1010                 1015                 1020             


Val Ala  Gln Ala Asn Leu Lys  Leu Leu Asp Val Ser  Lys Ile Phe 
    1025                 1030                 1035             


Pro Ile  Ala Glu Ile Ala Gly  Lys Ser His Glu Glu  Ser Ser Pro 
    1040                 1045                 1050             


Glu Val  Val Pro Val Glu Leu  Leu Cys Val Pro Ser  Pro Ala Ser 
    1055                 1060                 1065             


Gln Gly  Asp Leu His Thr Lys  Pro Leu Gly Thr Asp  Asp Asp Phe 
    1070                 1075                 1080             


Trp Gly  Pro Thr Gly Pro Val  Ala Thr Glu Val Val  Asp Lys Glu 
    1085                 1090                 1095             


Lys Asn  Leu Tyr Arg Val His  Phe Pro Val Ala Gly  Ser Tyr Arg 
    1100                 1105                 1110             


Trp Pro  Asn Thr Gly Leu Cys  Phe Val Met Arg Glu  Ala Val Thr 
    1115                 1120                 1125             


Val Glu  Ile Glu Phe Cys Val  Trp Asp Gln Phe Leu  Gly Glu Ile 
    1130                 1135                 1140             


Asn Pro  Gln His Ser Trp Met  Val Ala Gly Pro Leu  Leu Asp Ile 
    1145                 1150                 1155             


Lys Ala  Glu Pro Gly Ala Val  Glu Ala Val His Leu  Pro His Phe 
    1160                 1165                 1170             


Val Ala  Leu Gln Gly Gly His  Val Asp Thr Ser Leu  Phe Gln Met 
    1175                 1180                 1185             


Ala His  Phe Lys Glu Glu Gly  Met Leu Leu Glu Lys  Pro Ala Arg 
    1190                 1195                 1200             


Val Glu  Leu His His Ile Val  Leu Glu Asn Pro Ser  Phe Ser Pro 
    1205                 1210                 1215             


Leu Gly  Val Leu Leu Lys Met  Ile His Asn Ala Leu  Arg Phe Ile 
    1220                 1225                 1230             


Pro Val  Thr Ser Val Val Leu  Leu Tyr His Arg Val  His Pro Glu 
    1235                 1240                 1245             


Glu Val  Thr Phe His Leu Tyr  Leu Ile Pro Ser Asp  Cys Ser Ile 
    1250                 1255                 1260             


Arg Lys  Ala Ile Asp Asp Leu  Glu Met Lys Phe Gln  Phe Val Arg 
    1265                 1270                 1275             


Ile His  Lys Pro Pro Pro Leu  Thr Pro Leu Tyr Met  Gly Cys Arg 
    1280                 1285                 1290             


Tyr Thr  Val Ser Gly Ser Gly  Ser Gly Met Leu Glu  Ile Leu Pro 
    1295                 1300                 1305             


Lys Glu  Leu Glu Leu Cys Tyr  Arg Ser Pro Gly Glu  Asp Gln Leu 
    1310                 1315                 1320             


Phe Ser  Glu Phe Tyr Val Gly  His Leu Gly Ser Gly  Ile Arg Leu 
    1325                 1330                 1335             


Gln Val  Lys Asp Lys Lys Asp  Glu Thr Leu Val Trp  Glu Ala Leu 
    1340                 1345                 1350             


Val Lys  Pro Gly Arg Asn Thr  Ser Gln Pro Trp Asn  Leu Arg Cys 
    1355                 1360                 1365             


Asn Arg  Asp Ala Arg Arg Tyr  
    1370                 1375 


<210>  1225
<211>  384
<212>  PRT
<213>  Human

<400>  1225

Met Ala Gly Leu Gln Glu Leu Arg Phe Pro Glu Glu Lys Pro Leu Leu 
1               5                   10                  15      


Arg Gly Gln Asp Ala Thr Glu Leu Glu Ser Ser Asp Ala Phe Leu Leu 
            20                  25                  30          


Ala Ala Asp Thr Asp Trp Lys Glu His Asp Ile Glu Thr Pro Tyr Gly 
        35                  40                  45              


Leu Leu His Val Val Ile Arg Gly Ser Pro Lys Gly Asn Arg Pro Ala 
    50                  55                  60                  


Ile Leu Thr Tyr His Asp Val Gly Leu Asn His Lys Leu Cys Phe Asn 
65                  70                  75                  80  


Thr Phe Phe Asn Phe Glu Asp Met Gln Glu Ile Thr Lys His Phe Val 
                85                  90                  95      


Val Cys His Val Asp Ala Pro Gly Gln Gln Val Gly Ala Ser Gln Phe 
            100                 105                 110         


Pro Gln Gly Tyr Gln Phe Pro Ser Met Glu Gln Leu Ala Ala Met Leu 
        115                 120                 125             


Pro Ser Val Val Gln His Phe Gly Phe Lys Tyr Val Ile Gly Ile Gly 
    130                 135                 140                 


Val Gly Ala Gly Ala Tyr Val Leu Ala Lys Phe Ala Leu Ile Phe Pro 
145                 150                 155                 160 


Asp Leu Val Glu Gly Leu Val Leu Val Asn Ile Asp Pro Asn Gly Lys 
                165                 170                 175     


Gly Trp Ile Asp Trp Ala Ala Thr Lys Leu Ser Gly Leu Thr Ser Thr 
            180                 185                 190         


Leu Pro Asp Thr Val Leu Ser His Leu Phe Ser Gln Glu Glu Leu Val 
        195                 200                 205             


Asn Asn Thr Glu Leu Val Gln Ser Tyr Arg Gln Gln Ile Gly Asn Val 
    210                 215                 220                 


Val Asn Gln Ala Asn Leu Gln Leu Phe Trp Asn Met Tyr Asn Ser Arg 
225                 230                 235                 240 


Arg Asp Leu Asp Ile Asn Arg Pro Gly Thr Val Pro Asn Ala Lys Thr 
                245                 250                 255     


Leu Arg Cys Pro Val Met Leu Val Val Gly Asp Asn Ala Pro Ala Glu 
            260                 265                 270         


Asp Gly Val Val Glu Cys Asn Ser Lys Leu Asp Pro Thr Thr Thr Thr 
        275                 280                 285             


Phe Leu Lys Met Ala Asp Ser Gly Gly Leu Pro Gln Val Thr Gln Pro 
    290                 295                 300                 


Gly Lys Leu Thr Glu Ala Phe Lys Tyr Phe Leu Gln Gly Met Gly Tyr 
305                 310                 315                 320 


Ile Ala Tyr Leu Lys Asp Arg Arg Leu Ser Gly Gly Ala Val Pro Ser 
                325                 330                 335     


Ala Ser Met Thr Arg Leu Ala Arg Ser Arg Thr Ala Ser Leu Thr Ser 
            340                 345                 350         


Ala Ser Ser Val Asp Gly Ser Arg Pro Gln Ala Cys Thr His Ser Glu 
        355                 360                 365             


Ser Ser Glu Gly Leu Gly Gln Val Asn His Thr Met Glu Val Ser Cys 
    370                 375                 380                 


<210>  1226
<211>  471
<212>  PRT
<213>  Human

<400>  1226

Met Gln Ser Asn Lys Thr Phe Asn Leu Glu Lys Gln Asn His Thr Pro 
1               5                   10                  15      


Arg Lys His His Gln His His His Gln Gln Gln His His Gln Gln Gln 
            20                  25                  30          


Gln Gln Gln Pro Pro Pro Pro Pro Ile Pro Ala Asn Gly Gln Gln Ala 
        35                  40                  45              


Ser Ser Gln Asn Glu Gly Leu Thr Ile Asp Leu Lys Asn Phe Arg Lys 
    50                  55                  60                  


Pro Gly Glu Lys Thr Phe Thr Gln Arg Ser Arg Leu Phe Val Gly Asn 
65                  70                  75                  80  


Leu Pro Pro Asp Ile Thr Glu Glu Glu Met Arg Lys Leu Phe Glu Lys 
                85                  90                  95      


Tyr Gly Lys Ala Gly Glu Val Phe Ile His Lys Asp Lys Gly Phe Gly 
            100                 105                 110         


Phe Ile Arg Leu Glu Thr Arg Thr Leu Ala Glu Ile Ala Lys Val Glu 
        115                 120                 125             


Leu Asp Asn Met Pro Leu Arg Gly Lys Gln Leu Arg Val Arg Phe Ala 
    130                 135                 140                 


Cys His Ser Ala Ser Leu Thr Val Arg Asn Leu Pro Gln Tyr Val Ser 
145                 150                 155                 160 


Asn Glu Leu Leu Glu Glu Ala Phe Ser Val Phe Gly Gln Val Glu Arg 
                165                 170                 175     


Ala Val Val Ile Val Asp Asp Arg Gly Arg Pro Ser Gly Lys Gly Ile 
            180                 185                 190         


Val Glu Phe Ser Gly Lys Pro Ala Ala Arg Lys Ala Leu Asp Arg Cys 
        195                 200                 205             


Ser Glu Gly Ser Phe Leu Leu Thr Thr Phe Pro Arg Pro Val Thr Val 
    210                 215                 220                 


Glu Pro Met Asp Gln Leu Asp Asp Glu Glu Gly Leu Pro Glu Lys Leu 
225                 230                 235                 240 


Val Ile Lys Asn Gln Gln Phe His Lys Glu Arg Glu Gln Pro Pro Arg 
                245                 250                 255     


Phe Ala Gln Pro Gly Ser Phe Glu Tyr Glu Tyr Ala Met Arg Trp Lys 
            260                 265                 270         


Ala Leu Ile Glu Met Glu Lys Gln Gln Gln Asp Gln Val Asp Arg Asn 
        275                 280                 285             


Ile Lys Glu Ala Arg Glu Lys Leu Glu Met Glu Met Glu Ala Ala Arg 
    290                 295                 300                 


His Glu His Gln Val Met Leu Met Arg Gln Asp Leu Met Arg Arg Gln 
305                 310                 315                 320 


Glu Glu Leu Arg Arg Met Glu Glu Leu His Asn Gln Glu Val Gln Lys 
                325                 330                 335     


Arg Lys Gln Leu Glu Leu Arg Gln Glu Glu Glu Arg Arg Arg Arg Glu 
            340                 345                 350         


Glu Glu Met Arg Arg Gln Gln Glu Glu Met Met Arg Arg Gln Gln Glu 
        355                 360                 365             


Gly Phe Lys Gly Thr Phe Pro Asp Ala Arg Glu Gln Glu Ile Arg Met 
    370                 375                 380                 


Gly Gln Met Ala Met Gly Gly Ala Met Gly Ile Asn Asn Arg Gly Ala 
385                 390                 395                 400 


Met Pro Pro Ala Pro Val Pro Ala Gly Thr Pro Ala Pro Pro Gly Pro 
                405                 410                 415     


Ala Thr Met Met Pro Asp Gly Thr Leu Gly Leu Thr Pro Pro Thr Thr 
            420                 425                 430         


Glu Arg Phe Gly Gln Ala Ala Thr Met Glu Gly Ile Gly Ala Ile Gly 
        435                 440                 445             


Gly Thr Pro Pro Ala Phe Asn Arg Ala Ala Pro Gly Ala Glu Phe Ala 
    450                 455                 460                 


Pro Asn Lys Arg Arg Arg Tyr 
465                 470     


<210>  1227
<211>  287
<212>  PRT
<213>  Human

<400>  1227

Met Glu Val Met Glu Gly Pro Leu Asn Leu Ala His Gln Gln Ser Arg 
1               5                   10                  15      


Arg Ala Asp Arg Leu Leu Ala Ala Gly Lys Tyr Glu Glu Ala Ile Ser 
            20                  25                  30          


Cys His Lys Lys Ala Ala Ala Tyr Leu Ser Glu Ala Met Lys Leu Thr 
        35                  40                  45              


Gln Ser Glu Gln Ala His Leu Ser Leu Glu Leu Gln Arg Asp Ser His 
    50                  55                  60                  


Met Lys Gln Leu Leu Leu Ile Gln Glu Arg Trp Lys Arg Ala Gln Arg 
65                  70                  75                  80  


Glu Glu Arg Leu Lys Ala Gln Gln Asn Thr Asp Lys Asp Ala Ala Ala 
                85                  90                  95      


His Leu Gln Thr Ser His Lys Pro Ser Ala Glu Asp Ala Glu Gly Gln 
            100                 105                 110         


Ser Pro Leu Ser Gln Lys Tyr Ser Pro Ser Thr Glu Lys Cys Leu Pro 
        115                 120                 125             


Glu Ile Gln Gly Ile Phe Asp Arg Asp Pro Asp Thr Leu Leu Tyr Leu 
    130                 135                 140                 


Leu Gln Gln Lys Ser Glu Pro Ala Glu Pro Cys Ile Gly Ser Lys Ala 
145                 150                 155                 160 


Pro Lys Asp Asp Lys Thr Ile Ile Glu Glu Gln Ala Thr Lys Ile Ala 
                165                 170                 175     


Asp Leu Lys Arg His Val Glu Phe Leu Val Ala Glu Asn Glu Arg Leu 
            180                 185                 190         


Arg Lys Glu Asn Lys Gln Leu Lys Ala Glu Lys Ala Arg Leu Leu Lys 
        195                 200                 205             


Gly Pro Ile Glu Lys Glu Leu Asp Val Asp Ala Asp Phe Val Glu Thr 
    210                 215                 220                 


Ser Glu Leu Trp Ser Leu Pro Pro His Ala Glu Thr Ala Thr Ala Ser 
225                 230                 235                 240 


Ser Thr Trp Gln Lys Phe Ala Ala Asn Thr Gly Lys Ala Lys Asp Ile 
                245                 250                 255     


Pro Ile Pro Asn Leu Pro Pro Leu Asp Phe Pro Ser Pro Glu Leu Pro 
            260                 265                 270         


Leu Met Glu Leu Ser Glu Asp Ile Leu Lys Gly Phe Met Asn Asn 
        275                 280                 285         


<210>  1228
<211>  917
<212>  PRT
<213>  Human

<400>  1228

Met Ala Phe Ile Arg Lys Lys Gln Gln Glu Gln Gln Leu Gln Leu Tyr 
1               5                   10                  15      


Ser Lys Glu Arg Phe Ser Leu Leu Leu Leu Asn Leu Glu Glu Tyr Tyr 
            20                  25                  30          


Phe Glu Gln His Arg Ala Asn His Ile Leu His Lys Gly Ser His His 
        35                  40                  45              


Glu Arg Lys Ile Arg Gly Ser Leu Lys Ile Cys Ser Lys Ser Val Ile 
    50                  55                  60                  


Phe Glu Pro Asp Ser Ile Ser Gln Pro Ile Ile Lys Ile Pro Leu Arg 
65                  70                  75                  80  


Asp Cys Ile Lys Ile Gly Lys His Gly Glu Asn Gly Ala Asn Arg His 
                85                  90                  95      


Phe Thr Lys Ala Lys Ser Gly Gly Ile Ser Leu Ile Phe Ser Gln Val 
            100                 105                 110         


Tyr Phe Ile Lys Glu His Asn Val Val Ala Pro Tyr Lys Ile Glu Arg 
        115                 120                 125             


Gly Lys Met Glu Tyr Val Phe Glu Leu Asp Val Pro Gly Lys Val Glu 
    130                 135                 140                 


Asp Val Val Glu Thr Leu Leu Gln Leu His Arg Ala Ser Cys Leu Asp 
145                 150                 155                 160 


Lys Leu Gly Asp Gln Thr Ala Met Ile Thr Ala Ile Leu Gln Ser Arg 
                165                 170                 175     


Leu Ala Arg Thr Ser Phe Asp Lys Asn Arg Phe Gln Asn Ile Ser Glu 
            180                 185                 190         


Lys Leu His Met Glu Cys Lys Ala Glu Met Val Thr Pro Leu Val Thr 
        195                 200                 205             


Asn Pro Gly His Val Cys Ile Thr Asp Thr Asn Leu Tyr Phe Gln Pro 
    210                 215                 220                 


Leu Asn Gly Tyr Pro Lys Pro Val Val Gln Ile Thr Leu Gln Asp Val 
225                 230                 235                 240 


Arg Arg Ile Tyr Lys Arg Arg His Gly Leu Met Pro Leu Gly Leu Glu 
                245                 250                 255     


Val Phe Cys Thr Glu Asp Asp Leu Cys Ser Asp Ile Tyr Leu Lys Phe 
            260                 265                 270         


Tyr Glu Pro Gln Asp Arg Asp Asp Leu Tyr Phe Tyr Ile Ala Thr Tyr 
        275                 280                 285             


Leu Glu His His Val Ala Glu His Thr Ala Glu Ser Tyr Met Leu Gln 
    290                 295                 300                 


Trp Gln Arg Gly His Leu Ser Asn Tyr Gln Tyr Leu Leu His Leu Asn 
305                 310                 315                 320 


Asn Leu Ala Asp Arg Ser Cys Asn Asp Leu Ser Gln Tyr Pro Val Phe 
                325                 330                 335     


Pro Trp Ile Ile His Asp Tyr Ser Ser Ser Glu Leu Asp Leu Ser Asn 
            340                 345                 350         


Pro Gly Thr Phe Arg Asp Leu Ser Lys Pro Val Gly Ala Leu Asn Lys 
        355                 360                 365             


Glu Arg Leu Glu Arg Leu Leu Thr Arg Tyr Gln Glu Met Pro Glu Pro 
    370                 375                 380                 


Lys Phe Met Tyr Gly Ser His Tyr Ser Ser Pro Gly Tyr Val Leu Phe 
385                 390                 395                 400 


Tyr Leu Val Arg Ile Ala Pro Glu Tyr Met Leu Cys Leu Gln Asn Gly 
                405                 410                 415     


Arg Phe Asp Asn Ala Asp Arg Met Phe Asn Ser Ile Ala Glu Thr Trp 
            420                 425                 430         


Lys Asn Cys Leu Asp Gly Ala Thr Asp Phe Lys Glu Leu Ile Pro Glu 
        435                 440                 445             


Phe Tyr Gly Asp Asp Val Ser Phe Leu Val Asn Ser Leu Lys Leu Asp 
    450                 455                 460                 


Leu Gly Lys Arg Gln Gly Gly Gln Met Val Asp Asp Val Glu Leu Pro 
465                 470                 475                 480 


Pro Trp Ala Ser Ser Pro Glu Asp Phe Leu Gln Lys Ser Lys Asp Ala 
                485                 490                 495     


Leu Glu Ser Asn Tyr Val Ser Glu His Leu His Glu Trp Ile Asp Leu 
            500                 505                 510         


Ile Phe Gly Tyr Lys Gln Lys Gly Ser Asp Ala Val Gly Ala His Asn 
        515                 520                 525             


Val Phe His Pro Leu Thr Tyr Glu Gly Gly Val Asp Leu Asn Ser Ile 
    530                 535                 540                 


Gln Asp Pro Asp Glu Lys Val Ala Met Leu Thr Gln Ile Leu Glu Phe 
545                 550                 555                 560 


Gly Gln Thr Pro Lys Gln Leu Phe Val Thr Pro His Pro Arg Arg Ile 
                565                 570                 575     


Thr Pro Lys Phe Lys Ser Leu Ser Gln Thr Ser Ser Tyr Asn Ala Ser 
            580                 585                 590         


Met Ala Asp Ser Pro Gly Glu Glu Ser Phe Glu Asp Leu Thr Glu Glu 
        595                 600                 605             


Ser Lys Thr Leu Ala Trp Asn Asn Ile Thr Lys Leu Gln Leu His Glu 
    610                 615                 620                 


His Tyr Lys Ile His Lys Glu Ala Val Thr Gly Ile Thr Val Ser Arg 
625                 630                 635                 640 


Asn Gly Ser Ser Val Phe Thr Thr Ser Gln Asp Ser Thr Leu Lys Met 
                645                 650                 655     


Phe Ser Lys Glu Ser Lys Met Leu Gln Arg Ser Ile Ser Phe Ser Asn 
            660                 665                 670         


Met Ala Leu Ser Ser Cys Leu Leu Leu Pro Gly Asp Ala Thr Val Ile 
        675                 680                 685             


Thr Ser Ser Trp Asp Asn Asn Val Tyr Phe Tyr Ser Ile Ala Phe Gly 
    690                 695                 700                 


Arg Arg Gln Asp Thr Leu Met Gly His Asp Asp Ala Val Ser Lys Ile 
705                 710                 715                 720 


Cys Trp His Asp Asn Arg Leu Tyr Ser Ala Ser Trp Asp Ser Thr Val 
                725                 730                 735     


Lys Val Trp Ser Gly Val Pro Ala Glu Met Pro Gly Thr Lys Arg His 
            740                 745                 750         


His Phe Asp Leu Leu Ala Glu Leu Glu His Asp Val Ser Val Asp Thr 
        755                 760                 765             


Ile Ser Leu Asn Ala Ala Ser Thr Leu Leu Val Ser Gly Thr Lys Glu 
    770                 775                 780                 


Gly Thr Val Asn Ile Trp Asp Leu Thr Thr Ala Thr Leu Met His Gln 
785                 790                 795                 800 


Ile Pro Cys His Ser Gly Ile Val Cys Asp Thr Ala Phe Ser Pro Asp 
                805                 810                 815     


Ser Arg His Val Leu Ser Thr Gly Thr Asp Gly Cys Leu Asn Val Ile 
            820                 825                 830         


Asp Val Gln Thr Gly Met Leu Ile Ser Ser Met Thr Ser Asp Glu Pro 
        835                 840                 845             


Gln Arg Cys Phe Val Trp Asp Gly Asn Ser Val Leu Ser Gly Ser Gln 
    850                 855                 860                 


Ser Gly Glu Leu Leu Val Trp Asp Leu Leu Gly Ala Lys Ile Ser Glu 
865                 870                 875                 880 


Arg Ile Gln Gly His Thr Gly Ala Val Thr Cys Ile Trp Met Asn Glu 
                885                 890                 895     


Gln Cys Ser Ser Ile Ile Thr Gly Gly Glu Asp Arg Gln Ile Ile Phe 
            900                 905                 910         


Trp Lys Leu Gln Tyr 
        915         


<210>  1229
<211>  2115
<212>  PRT
<213>  Human

<400>  1229

Met Thr Leu His Ala Thr Arg Gly Ala Ala Leu Leu Ser Trp Val Asn 
1               5                   10                  15      


Ser Leu His Val Ala Asp Pro Val Glu Ala Val Leu Gln Leu Gln Asp 
            20                  25                  30          


Cys Ser Ile Phe Ile Lys Ile Ile Asp Arg Ile His Gly Thr Glu Glu 
        35                  40                  45              


Gly Gln Gln Ile Leu Lys Gln Pro Val Ser Glu Arg Leu Asp Phe Val 
    50                  55                  60                  


Cys Ser Phe Leu Gln Lys Asn Arg Lys His Pro Ser Ser Pro Glu Cys 
65                  70                  75                  80  


Leu Val Ser Ala Gln Lys Val Leu Glu Gly Ser Glu Leu Glu Leu Ala 
                85                  90                  95      


Lys Met Thr Met Leu Leu Leu Tyr His Ser Thr Met Ser Ser Lys Ser 
            100                 105                 110         


Pro Arg Asp Trp Glu Gln Phe Glu Tyr Lys Ile Gln Ala Glu Leu Ala 
        115                 120                 125             


Val Ile Leu Lys Phe Val Leu Asp His Glu Asp Gly Leu Asn Leu Asn 
    130                 135                 140                 


Glu Asp Leu Glu Asn Phe Leu Gln Lys Ala Pro Val Pro Ser Thr Cys 
145                 150                 155                 160 


Ser Ser Thr Phe Pro Glu Glu Leu Ser Pro Pro Ser His Gln Ala Lys 
                165                 170                 175     


Arg Glu Ile Arg Phe Leu Glu Leu Gln Lys Val Ala Ser Ser Ser Ser 
            180                 185                 190         


Gly Asn Asn Phe Leu Ser Gly Ser Pro Ala Ser Pro Met Gly Asp Ile 
        195                 200                 205             


Leu Gln Thr Pro Gln Phe Gln Met Arg Arg Leu Lys Lys Gln Leu Ala 
    210                 215                 220                 


Asp Glu Arg Ser Asn Arg Asp Glu Leu Glu Leu Glu Leu Ala Glu Asn 
225                 230                 235                 240 


Arg Lys Leu Leu Thr Glu Lys Asp Ala Gln Ile Ala Met Met Gln Gln 
                245                 250                 255     


Arg Ile Asp Arg Leu Ala Leu Leu Asn Glu Lys Gln Ala Ala Ser Pro 
            260                 265                 270         


Leu Glu Pro Lys Glu Leu Glu Glu Leu Arg Asp Lys Asn Glu Ser Leu 
        275                 280                 285             


Thr Met Arg Leu His Glu Thr Leu Lys Gln Cys Gln Asp Leu Lys Thr 
    290                 295                 300                 


Glu Lys Ser Gln Met Asp Arg Lys Ile Asn Gln Leu Ser Glu Glu Asn 
305                 310                 315                 320 


Gly Asp Leu Ser Phe Lys Leu Arg Glu Phe Ala Ser His Leu Gln Gln 
                325                 330                 335     


Leu Gln Asp Ala Leu Asn Glu Leu Thr Glu Glu His Ser Lys Ala Thr 
            340                 345                 350         


Gln Glu Trp Leu Glu Lys Gln Ala Gln Leu Glu Lys Glu Leu Ser Ala 
        355                 360                 365             


Ala Leu Gln Asp Lys Lys Cys Leu Glu Glu Lys Asn Glu Ile Leu Gln 
    370                 375                 380                 


Gly Lys Leu Ser Gln Leu Glu Glu His Leu Ser Gln Leu Gln Asp Asn 
385                 390                 395                 400 


Pro Pro Gln Glu Lys Gly Glu Val Leu Gly Asp Val Leu Gln Leu Glu 
                405                 410                 415     


Thr Leu Lys Gln Glu Ala Ala Thr Leu Ala Ala Asn Asn Thr Gln Leu 
            420                 425                 430         


Gln Ala Arg Val Glu Met Leu Glu Thr Glu Arg Gly Gln Gln Glu Ala 
        435                 440                 445             


Lys Leu Leu Ala Glu Arg Gly His Phe Glu Glu Glu Lys Gln Gln Leu 
    450                 455                 460                 


Ser Ser Leu Ile Thr Asp Leu Gln Ser Ser Ile Ser Asn Leu Ser Gln 
465                 470                 475                 480 


Ala Lys Glu Glu Leu Glu Gln Ala Ser Gln Ala His Gly Ala Arg Leu 
                485                 490                 495     


Thr Ala Gln Val Ala Ser Leu Thr Ser Glu Leu Thr Thr Leu Asn Ala 
            500                 505                 510         


Thr Ile Gln Gln Gln Asp Gln Glu Leu Ala Gly Leu Lys Gln Gln Ala 
        515                 520                 525             


Lys Glu Lys Gln Ala Gln Leu Ala Gln Thr Leu Gln Gln Gln Glu Gln 
    530                 535                 540                 


Ala Ser Gln Gly Leu Arg His Gln Val Glu Gln Leu Ser Ser Ser Leu 
545                 550                 555                 560 


Lys Gln Lys Glu Gln Gln Leu Lys Glu Val Ala Glu Lys Gln Glu Ala 
                565                 570                 575     


Thr Arg Gln Asp His Ala Gln Gln Leu Ala Thr Ala Ala Glu Glu Arg 
            580                 585                 590         


Glu Ala Ser Leu Arg Glu Arg Asp Ala Ala Leu Lys Gln Leu Glu Ala 
        595                 600                 605             


Leu Glu Lys Glu Lys Ala Ala Lys Leu Glu Ile Leu Gln Gln Gln Leu 
    610                 615                 620                 


Gln Val Ala Asn Glu Ala Arg Asp Ser Ala Gln Thr Ser Val Thr Gln 
625                 630                 635                 640 


Ala Gln Arg Glu Lys Ala Glu Leu Ser Arg Lys Val Glu Glu Leu Gln 
                645                 650                 655     


Ala Cys Val Glu Thr Ala Arg Gln Glu Gln His Glu Ala Gln Ala Gln 
            660                 665                 670         


Val Ala Glu Leu Glu Leu Gln Leu Arg Ser Glu Gln Gln Lys Ala Thr 
        675                 680                 685             


Glu Lys Glu Arg Val Ala Gln Glu Lys Asp Gln Leu Gln Glu Gln Leu 
    690                 695                 700                 


Gln Ala Leu Lys Glu Ser Leu Lys Val Thr Lys Gly Ser Leu Glu Glu 
705                 710                 715                 720 


Glu Lys Arg Arg Ala Ala Asp Ala Leu Glu Glu Gln Gln Arg Cys Ile 
                725                 730                 735     


Ser Glu Leu Lys Ala Glu Thr Arg Ser Leu Val Glu Gln His Lys Arg 
            740                 745                 750         


Glu Arg Lys Glu Leu Glu Glu Glu Arg Ala Gly Arg Lys Gly Leu Glu 
        755                 760                 765             


Ala Arg Leu Gln Gln Leu Gly Glu Ala His Gln Ala Glu Thr Glu Val 
    770                 775                 780                 


Leu Arg Arg Glu Leu Ala Glu Ala Met Ala Ala Gln His Thr Ala Glu 
785                 790                 795                 800 


Ser Glu Cys Glu Gln Leu Val Lys Glu Val Ala Ala Trp Arg Glu Arg 
                805                 810                 815     


Tyr Glu Asp Ser Gln Gln Glu Glu Ala Gln Tyr Gly Ala Met Phe Gln 
            820                 825                 830         


Glu Gln Leu Met Thr Leu Lys Glu Glu Cys Glu Lys Ala Arg Gln Glu 
        835                 840                 845             


Leu Gln Glu Ala Lys Glu Lys Val Ala Gly Ile Glu Ser His Ser Glu 
    850                 855                 860                 


Leu Gln Ile Ser Arg Gln Gln Asn Glu Leu Ala Glu Leu His Ala Asn 
865                 870                 875                 880 


Leu Ala Arg Ala Leu Gln Gln Val Gln Glu Lys Glu Val Arg Ala Gln 
                885                 890                 895     


Lys Leu Ala Asp Asp Leu Ser Thr Leu Gln Glu Lys Met Ala Ala Thr 
            900                 905                 910         


Ser Lys Glu Val Ala Arg Leu Glu Thr Leu Val Arg Lys Ala Gly Glu 
        915                 920                 925             


Gln Gln Glu Thr Ala Ser Arg Glu Leu Val Lys Glu Pro Ala Arg Ala 
    930                 935                 940                 


Gly Asp Arg Gln Pro Glu Trp Leu Glu Glu Gln Gln Gly Arg Gln Phe 
945                 950                 955                 960 


Cys Ser Thr Gln Ala Ala Leu Gln Ala Met Glu Arg Glu Ala Glu Gln 
                965                 970                 975     


Met Gly Asn Glu Leu Glu Arg Leu Arg Ala Ala Leu Met Glu Ser Gln 
            980                 985                 990         


Gly Gln Gln Gln Glu Glu Arg Gly  Gln Gln Glu Arg Glu  Val Ala Arg 
        995                 1000                 1005             


Leu Thr  Gln Glu Arg Gly Arg  Ala Gln Ala Asp Leu  Ala Leu Glu 
    1010                 1015                 1020             


Lys Ala  Ala Arg Ala Glu Leu  Glu Met Arg Leu Gln  Asn Ala Leu 
    1025                 1030                 1035             


Asn Glu  Gln Arg Val Glu Phe  Ala Thr Leu Gln Glu  Ala Leu Ala 
    1040                 1045                 1050             


His Ala  Leu Thr Glu Lys Glu  Gly Lys Asp Gln Glu  Leu Ala Lys 
    1055                 1060                 1065             


Leu Arg  Gly Leu Glu Ala Ala  Gln Ile Lys Glu Leu  Glu Glu Leu 
    1070                 1075                 1080             


Arg Gln  Thr Val Lys Gln Leu  Lys Glu Gln Leu Ala  Lys Lys Glu 
    1085                 1090                 1095             


Lys Glu  His Ala Ser Gly Ser  Gly Ala Gln Ser Glu  Ala Ala Gly 
    1100                 1105                 1110             


Arg Thr  Glu Pro Thr Gly Pro  Lys Leu Glu Ala Leu  Arg Ala Glu 
    1115                 1120                 1125             


Val Ser  Lys Leu Glu Gln Gln  Cys Gln Lys Gln Gln  Glu Gln Ala 
    1130                 1135                 1140             


Asp Ser  Leu Glu Arg Ser Leu  Glu Ala Glu Arg Ala  Ser Arg Ala 
    1145                 1150                 1155             


Glu Arg  Asp Ser Ala Leu Glu  Thr Leu Gln Gly Gln  Leu Glu Glu 
    1160                 1165                 1170             


Lys Ala  Gln Glu Leu Gly His  Ser Gln Ser Ala Leu  Ala Ser Ala 
    1175                 1180                 1185             


Gln Arg  Glu Leu Ala Ala Phe  Arg Thr Lys Val Gln  Asp His Ser 
    1190                 1195                 1200             


Lys Ala  Glu Asp Glu Trp Lys  Ala Gln Val Ala Arg  Gly Arg Gln 
    1205                 1210                 1215             


Glu Ala  Glu Arg Lys Asn Ser  Leu Ile Ser Ser Leu  Glu Glu Glu 
    1220                 1225                 1230             


Val Ser  Ile Leu Asn Arg Gln  Val Leu Glu Lys Glu  Gly Glu Ser 
    1235                 1240                 1245             


Lys Glu  Leu Lys Arg Leu Val  Met Ala Glu Ser Glu  Lys Ser Gln 
    1250                 1255                 1260             


Lys Leu  Glu Glu Arg Leu Arg  Leu Leu Gln Ala Glu  Thr Ala Ser 
    1265                 1270                 1275             


Asn Ser  Ala Arg Ala Ala Glu  Arg Ser Ser Ala Leu  Arg Glu Glu 
    1280                 1285                 1290             


Val Gln  Ser Leu Arg Glu Glu  Ala Glu Lys Gln Arg  Val Ala Ser 
    1295                 1300                 1305             


Glu Asn  Leu Arg Gln Glu Leu  Thr Ser Gln Ala Glu  Arg Ala Glu 
    1310                 1315                 1320             


Glu Leu  Gly Gln Glu Leu Lys  Ala Trp Gln Glu Lys  Phe Phe Gln 
    1325                 1330                 1335             


Lys Glu  Gln Ala Leu Ser Thr  Leu Gln Leu Glu His  Thr Ser Thr 
    1340                 1345                 1350             


Gln Ala  Leu Val Ser Glu Leu  Leu Pro Ala Lys His  Leu Cys Gln 
    1355                 1360                 1365             


Gln Leu  Gln Ala Glu Gln Ala  Ala Ala Glu Lys Arg  His Arg Glu 
    1370                 1375                 1380             


Glu Leu  Glu Gln Ser Lys Gln  Ala Ala Gly Gly Leu  Arg Ala Glu 
    1385                 1390                 1395             


Leu Leu  Arg Ala Gln Arg Glu  Leu Gly Glu Leu Ile  Pro Leu Arg 
    1400                 1405                 1410             


Gln Lys  Val Ala Glu Gln Glu  Arg Thr Ala Gln Gln  Leu Arg Ala 
    1415                 1420                 1425             


Glu Lys  Ala Ser Tyr Ala Glu  Gln Leu Ser Met Leu  Lys Lys Ala 
    1430                 1435                 1440             


His Gly  Leu Leu Ala Glu Glu  Asn Arg Gly Leu Gly  Glu Arg Ala 
    1445                 1450                 1455             


Asn Leu  Gly Arg Gln Phe Leu  Glu Val Glu Leu Asp  Gln Ala Arg 
    1460                 1465                 1470             


Glu Lys  Tyr Val Gln Glu Leu  Ala Ala Val Arg Ala  Asp Ala Glu 
    1475                 1480                 1485             


Thr Arg  Leu Ala Glu Val Gln  Arg Glu Ala Gln Ser  Thr Ala Arg 
    1490                 1495                 1500             


Glu Leu  Glu Val Met Thr Ala  Lys Tyr Glu Gly Ala  Lys Val Lys 
    1505                 1510                 1515             


Val Leu  Glu Glu Arg Gln Arg  Phe Gln Glu Glu Arg  Gln Lys Leu 
    1520                 1525                 1530             


Thr Ala  Gln Val Glu Gln Leu  Glu Val Phe Gln Arg  Glu Gln Thr 
    1535                 1540                 1545             


Lys Gln  Val Glu Glu Leu Ser  Lys Lys Leu Ala Asp  Ser Asp Gln 
    1550                 1555                 1560             


Ala Ser  Lys Val Gln Gln Gln  Lys Leu Lys Ala Val  Gln Ala Gln 
    1565                 1570                 1575             


Gly Gly  Glu Ser Gln Gln Glu  Ala Gln Arg Leu Gln  Ala Gln Leu 
    1580                 1585                 1590             


Asn Glu  Leu Gln Ala Gln Leu  Ser Gln Lys Glu Gln  Ala Ala Glu 
    1595                 1600                 1605             


His Tyr  Lys Leu Gln Met Glu  Lys Ala Lys Thr His  Tyr Asp Ala 
    1610                 1615                 1620             


Lys Lys  Gln Gln Asn Gln Glu  Leu Gln Glu Gln Leu  Arg Ser Leu 
    1625                 1630                 1635             


Glu Gln  Leu Gln Lys Glu Asn  Lys Glu Leu Arg Ala  Glu Ala Glu 
    1640                 1645                 1650             


Arg Leu  Gly His Glu Leu Gln  Gln Ala Gly Leu Lys  Thr Lys Glu 
    1655                 1660                 1665             


Ala Glu  Gln Thr Cys Arg His  Leu Thr Ala Gln Val  Arg Ser Leu 
    1670                 1675                 1680             


Glu Ala  Gln Val Ala His Ala  Asp Gln Gln Leu Arg  Asp Leu Gly 
    1685                 1690                 1695             


Lys Phe  Gln Val Ala Thr Asp  Ala Leu Lys Ser Arg  Glu Pro Gln 
    1700                 1705                 1710             


Ala Lys  Pro Gln Leu Asp Leu  Ser Ile Asp Ser Leu  Asp Leu Ser 
    1715                 1720                 1725             


Cys Glu  Glu Gly Thr Pro Leu  Ser Ile Thr Ser Lys  Leu Pro Arg 
    1730                 1735                 1740             


Thr Gln  Pro Asp Gly Thr Ser  Val Pro Gly Glu Pro  Ala Ser Pro 
    1745                 1750                 1755             


Ile Ser  Gln Arg Leu Pro Pro  Lys Val Glu Ser Leu  Glu Ser Leu 
    1760                 1765                 1770             


Tyr Phe  Thr Pro Ile Pro Ala  Arg Ser Gln Ala Pro  Leu Glu Ser 
    1775                 1780                 1785             


Ser Leu  Asp Ser Leu Gly Asp  Val Phe Leu Asp Ser  Gly Arg Lys 
    1790                 1795                 1800             


Thr Arg  Ser Ala Arg Arg Arg  Thr Thr Gln Ile Ile  Asn Ile Thr 
    1805                 1810                 1815             


Met Thr  Lys Lys Leu Asp Val  Glu Glu Pro Asp Ser  Ala Asn Ser 
    1820                 1825                 1830             


Ser Phe  Tyr Ser Thr Arg Ser  Ala Pro Ala Ser Gln  Ala Ser Leu 
    1835                 1840                 1845             


Arg Ala  Thr Ser Ser Thr Gln  Ser Leu Ala Arg Leu  Gly Ser Pro 
    1850                 1855                 1860             


Asp Tyr  Gly Asn Ser Ala Leu  Leu Ser Leu Pro Gly  Tyr Arg Pro 
    1865                 1870                 1875             


Thr Thr  Arg Ser Ser Ala Arg  Arg Ser Gln Ala Gly  Val Ser Ser 
    1880                 1885                 1890             


Gly Ala  Pro Pro Gly Arg Asn  Ser Phe Tyr Met Gly  Thr Cys Gln 
    1895                 1900                 1905             


Asp Glu  Pro Glu Gln Leu Asp  Asp Trp Asn Arg Ile  Ala Glu Leu 
    1910                 1915                 1920             


Gln Gln  Arg Asn Arg Val Cys  Pro Pro His Leu Lys  Thr Cys Tyr 
    1925                 1930                 1935             


Pro Leu  Glu Ser Arg Pro Ser  Leu Ser Leu Gly Thr  Ile Thr Asp 
    1940                 1945                 1950             


Glu Glu  Met Lys Thr Gly Asp  Pro Gln Glu Thr Leu  Arg Arg Ala 
    1955                 1960                 1965             


Ser Met  Gln Pro Ile Gln Ile  Ala Glu Gly Thr Gly  Ile Thr Thr 
    1970                 1975                 1980             


Arg Gln  Gln Arg Lys Arg Val  Ser Leu Glu Pro His  Gln Gly Pro 
    1985                 1990                 1995             


Gly Thr  Pro Glu Ser Lys Lys  Ala Thr Ser Cys Phe  Pro Arg Pro 
    2000                 2005                 2010             


Met Thr  Pro Arg Asp Arg His  Glu Gly Arg Lys Gln  Ser Thr Thr 
    2015                 2020                 2025             


Glu Ala  Gln Lys Lys Ala Ala  Pro Ala Ser Thr Lys  Gln Ala Asp 
    2030                 2035                 2040             


Arg Arg  Gln Ser Met Ala Phe  Ser Ile Leu Asn Thr  Pro Lys Lys 
    2045                 2050                 2055             


Leu Gly  Asn Ser Leu Leu Arg  Arg Gly Ala Ser Lys  Lys Ala Leu 
    2060                 2065                 2070             


Ser Lys  Ala Ser Pro Asn Thr  Arg Ser Gly Thr Arg  Arg Ser Pro 
    2075                 2080                 2085             


Arg Ile  Ala Thr Thr Thr Ala  Ser Ala Ala Thr Ala  Ala Ala Ile 
    2090                 2095                 2100             


Gly Ala  Thr Pro Arg Ala Lys  Gly Lys Ala Lys His  
    2105                 2110                 2115 


<210>  1230
<211>  259
<212>  PRT
<213>  Human

<400>  1230

Met Ala Ser Pro Gln Gly Gly Gln Ile Ala Ile Ala Met Arg Leu Arg 
1               5                   10                  15      


Asn Gln Leu Gln Ser Val Tyr Lys Met Asp Pro Leu Arg Asn Glu Glu 
            20                  25                  30          


Glu Val Arg Val Lys Ile Lys Asp Leu Asn Glu His Ile Val Cys Cys 
        35                  40                  45              


Leu Cys Ala Gly Tyr Phe Val Asp Ala Thr Thr Ile Thr Glu Cys Leu 
    50                  55                  60                  


His Thr Phe Cys Lys Ser Cys Ile Val Lys Tyr Leu Gln Thr Ser Lys 
65                  70                  75                  80  


Tyr Cys Pro Met Cys Asn Ile Lys Ile His Glu Thr Gln Pro Leu Leu 
                85                  90                  95      


Asn Leu Lys Leu Asp Arg Val Met Gln Asp Ile Val Tyr Lys Leu Val 
            100                 105                 110         


Pro Gly Leu Gln Asp Ser Glu Glu Lys Arg Ile Arg Glu Phe Tyr Gln 
        115                 120                 125             


Ser Arg Gly Leu Asp Arg Val Thr Gln Pro Thr Gly Glu Glu Pro Ala 
    130                 135                 140                 


Leu Ser Asn Leu Gly Leu Pro Phe Ser Ser Phe Asp His Ser Lys Ala 
145                 150                 155                 160 


His Tyr Tyr Arg Tyr Asp Glu Gln Leu Asn Leu Cys Leu Glu Arg Leu 
                165                 170                 175     


Ser Ser Gly Lys Asp Lys Asn Lys Ser Val Leu Gln Asn Lys Tyr Val 
            180                 185                 190         


Arg Cys Ser Val Arg Ala Glu Val Arg His Leu Arg Arg Val Leu Cys 
        195                 200                 205             


His Arg Leu Met Leu Asn Pro Gln His Val Gln Leu Leu Phe Asp Asn 
    210                 215                 220                 


Glu Val Leu Pro Asp His Met Thr Met Lys Gln Ile Trp Leu Ser Arg 
225                 230                 235                 240 


Trp Phe Gly Lys Pro Ser Pro Leu Leu Leu Gln Tyr Ser Val Lys Glu 
                245                 250                 255     


Lys Arg Arg 
            


<210>  1231
<211>  358
<212>  PRT
<213>  Human

<400>  1231

Met Ala Ala Val Leu Lys Pro Val Leu Leu Gly Leu Arg Asp Ala Pro 
1               5                   10                  15      


Val His Gly Ser Pro Thr Gly Pro Gly Ala Trp Thr Ala Ser Lys Leu 
            20                  25                  30          


Gly Gly Ile Pro Asp Ala Leu Pro Thr Val Ala Ala Pro Arg Pro Val 
        35                  40                  45              


Cys Gln Arg Cys Gly Gln Pro Leu Ala Leu Val Val Gln Val Tyr Cys 
    50                  55                  60                  


Pro Leu Glu Gly Ser Pro Phe His Arg Leu Leu His Val Phe Ala Cys 
65                  70                  75                  80  


Ala Cys Pro Gly Cys Ser Thr Gly Gly Ala Arg Ser Trp Lys Val Phe 
                85                  90                  95      


Arg Ser Gln Cys Leu Gln Val Pro Glu Arg Glu Ala Gln Asp Ala Gln 
            100                 105                 110         


Lys Gln Gly Asn Ser Leu Ala Ala Glu Asp Trp Cys Glu Gly Ala Asp 
        115                 120                 125             


Asp Trp Gly Ser Asp Thr Glu Glu Gly Pro Ser Pro Gln Phe Thr Leu 
    130                 135                 140                 


Asp Phe Gly Asn Asp Ala Ser Ser Ala Lys Asp Val Asp Trp Thr Ala 
145                 150                 155                 160 


Arg Leu Gln Asp Leu Arg Leu Gln Asp Ala Val Leu Gly Ala Ala His 
                165                 170                 175     


Pro Val Pro Pro Gly Leu Pro Leu Phe Leu Pro Tyr Tyr Ile Cys Val 
            180                 185                 190         


Ala Asp Glu Asp Asp Tyr Arg Asp Phe Val Asn Leu Asp His Ala His 
        195                 200                 205             


Ser Leu Leu Arg Asp Tyr Gln Gln Arg Glu Gly Ile Ala Met Asp Gln 
    210                 215                 220                 


Leu Leu Ser Gln Ser Leu Pro Asn Asp Gly Asp Glu Lys Tyr Glu Lys 
225                 230                 235                 240 


Thr Ile Ile Lys Ser Gly Asp Gln Thr Phe Tyr Lys Phe Met Lys Arg 
                245                 250                 255     


Ile Ala Ala Cys Gln Glu Gln Ile Leu Arg Tyr Ser Trp Ser Gly Glu 
            260                 265                 270         


Pro Leu Phe Leu Thr Cys Pro Thr Ser Glu Val Thr Glu Leu Pro Ala 
        275                 280                 285             


Cys Ser Gln Cys Gly Gly Gln Arg Ile Phe Glu Phe Gln Leu Met Pro 
    290                 295                 300                 


Ala Leu Val Ser Met Leu Lys Ser Ala Asn Leu Gly Leu Ser Val Glu 
305                 310                 315                 320 


Phe Gly Thr Ile Leu Val Tyr Thr Cys Glu Lys Ser Cys Trp Pro Pro 
                325                 330                 335     


Asn His Gln Thr Pro Met Glu Glu Phe Cys Ile Ile Gln Glu Asp Pro 
            340                 345                 350         


Asp Glu Leu Leu Phe Lys 
        355             


<210>  1232
<211>  377
<212>  PRT
<213>  Human

<400>  1232

Met Ala Ser Ser Glu Gln Ala Glu Gln Pro Ser Gln Pro Ser Ser Thr 
1               5                   10                  15      


Pro Gly Ser Glu Asn Val Leu Pro Arg Glu Pro Leu Ile Ala Thr Ala 
            20                  25                  30          


Val Lys Phe Leu Gln Asn Ser Arg Val Arg Gln Ser Pro Leu Ala Thr 
        35                  40                  45              


Arg Arg Ala Phe Leu Lys Lys Lys Gly Leu Thr Asp Glu Glu Ile Asp 
    50                  55                  60                  


Met Ala Phe Gln Gln Ser Gly Thr Ala Ala Asp Glu Pro Ser Ser Leu 
65                  70                  75                  80  


Gly Pro Ala Thr Gln Val Val Pro Val Gln Pro Pro His Leu Ile Ser 
                85                  90                  95      


Gln Pro Tyr Ser Pro Ala Gly Ser Arg Trp Arg Asp Tyr Gly Ala Leu 
            100                 105                 110         


Ala Ile Ile Met Ala Gly Ile Ala Phe Gly Phe His Gln Leu Tyr Lys 
        115                 120                 125             


Lys Tyr Leu Leu Pro Leu Ile Leu Gly Gly Arg Glu Asp Arg Lys Gln 
    130                 135                 140                 


Leu Glu Arg Met Glu Ala Gly Leu Ser Glu Leu Ser Gly Ser Val Ala 
145                 150                 155                 160 


Gln Thr Val Thr Gln Leu Gln Thr Thr Leu Ala Ser Val Gln Glu Leu 
                165                 170                 175     


Leu Ile Gln Gln Gln Gln Lys Ile Gln Glu Leu Ala His Glu Leu Ala 
            180                 185                 190         


Ala Ala Lys Ala Thr Thr Ser Thr Asn Trp Ile Leu Glu Ser Gln Asn 
        195                 200                 205             


Ile Asn Glu Leu Lys Ser Glu Ile Asn Ser Leu Lys Gly Leu Leu Leu 
    210                 215                 220                 


Asn Arg Arg Gln Phe Pro Pro Ser Pro Ser Ala Pro Lys Ile Pro Ser 
225                 230                 235                 240 


Trp Gln Ile Pro Val Lys Ser Pro Ser Pro Ser Ser Pro Ala Ala Val 
                245                 250                 255     


Asn His His Ser Ser Ser Asp Ile Ser Pro Val Ser Asn Glu Ser Thr 
            260                 265                 270         


Ser Ser Ser Pro Gly Lys Glu Gly His Ser Pro Glu Gly Ser Thr Val 
        275                 280                 285             


Thr Tyr His Leu Leu Gly Pro Gln Glu Glu Gly Glu Gly Val Val Asp 
    290                 295                 300                 


Val Lys Gly Gln Val Arg Met Glu Val Gln Gly Glu Glu Glu Lys Arg 
305                 310                 315                 320 


Glu Asp Lys Glu Asp Glu Glu Asp Glu Glu Asp Asp Asp Val Ser His 
                325                 330                 335     


Val Asp Glu Glu Asp Cys Leu Gly Val Gln Arg Glu Asp Arg Arg Gly 
            340                 345                 350         


Gly Asp Gly Gln Ile Asn Glu Gln Val Glu Lys Leu Arg Arg Pro Glu 
        355                 360                 365             


Gly Ala Ser Asn Glu Ser Glu Arg Asp 
    370                 375         


<210>  1233
<211>  581
<212>  PRT
<213>  Human

<400>  1233

Met Val Leu Lys Ala Phe Phe Pro Thr Cys Cys Val Ser Thr Asp Ser 
1               5                   10                  15      


Gly Leu Leu Val Gly Arg Trp Val Pro Glu Gln Ser Ser Ala Val Val 
            20                  25                  30          


Leu Ala Val Leu His Phe Pro Phe Ile Pro Ile Gln Val Lys Gln Leu 
        35                  40                  45              


Leu Ala Gln Val Arg Gln Ala Ser Gln Val Gly Val Ala Val Leu Gly 
    50                  55                  60                  


Thr Trp Cys His Cys Arg Gln Glu Pro Glu Glu Ser Leu Gly Arg Phe 
65                  70                  75                  80  


Leu Glu Ser Leu Gly Ala Val Phe Pro His Glu Pro Trp Leu Arg Leu 
                85                  90                  95      


Cys Arg Glu Arg Gly Gly Thr Phe Trp Ser Cys Glu Ala Thr His Arg 
            100                 105                 110         


Gln Ala Pro Thr Ala Pro Gly Ala Pro Gly Glu Asp Gln Val Met Leu 
        115                 120                 125             


Ile Phe Tyr Asp Gln Arg Gln Val Leu Leu Ser Gln Leu His Leu Pro 
    130                 135                 140                 


Thr Val Leu Pro Asp Arg Gln Ala Gly Ala Thr Thr Ala Ser Thr Gly 
145                 150                 155                 160 


Gly Leu Ala Ala Val Phe Asp Thr Val Ala Arg Ser Glu Val Leu Phe 
                165                 170                 175     


Arg Ser Asp Arg Phe Asp Glu Gly Pro Val Arg Leu Ser His Trp Gln 
            180                 185                 190         


Ser Glu Gly Val Glu Ala Ser Ile Leu Ala Glu Leu Ala Arg Arg Ala 
        195                 200                 205             


Ser Gly Pro Ile Cys Leu Leu Leu Ala Ser Leu Leu Ser Leu Val Ser 
    210                 215                 220                 


Ala Val Ser Ala Cys Arg Val Phe Lys Leu Trp Pro Leu Ser Phe Leu 
225                 230                 235                 240 


Gly Ser Lys Leu Ser Thr Cys Glu Gln Leu Arg His Arg Leu Glu His 
                245                 250                 255     


Leu Thr Leu Ile Phe Ser Thr Arg Lys Ala Glu Asn Pro Ala Gln Leu 
            260                 265                 270         


Met Arg Lys Ala Asn Thr Val Ala Ser Val Leu Leu Asp Val Ala Leu 
        275                 280                 285             


Gly Leu Met Leu Leu Ser Trp Leu His Gly Arg Ser Arg Ile Gly His 
    290                 295                 300                 


Leu Ala Asp Ala Leu Val Pro Val Ala Asp His Val Ala Glu Glu Leu 
305                 310                 315                 320 


Gln His Leu Leu Gln Trp Leu Met Gly Ala Pro Ala Gly Leu Lys Met 
                325                 330                 335     


Asn Arg Ala Leu Asp Gln Val Leu Gly Arg Phe Phe Leu Tyr His Ile 
            340                 345                 350         


His Leu Trp Ile Ser Tyr Ile His Leu Met Ser Pro Phe Val Glu His 
        355                 360                 365             


Ile Leu Trp His Val Gly Leu Ser Ala Cys Leu Gly Leu Thr Val Ala 
    370                 375                 380                 


Leu Ser Leu Leu Ser Asp Ile Ile Ala Leu Leu Thr Phe His Ile Tyr 
385                 390                 395                 400 


Cys Phe Tyr Val Tyr Gly Ala Arg Leu Tyr Cys Leu Lys Ile His Gly 
                405                 410                 415     


Leu Ser Ser Leu Trp Arg Leu Phe Arg Gly Lys Lys Trp Asn Val Leu 
            420                 425                 430         


Arg Gln Arg Val Asp Ser Cys Ser Tyr Asp Leu Asp Gln Leu Phe Ile 
        435                 440                 445             


Gly Thr Leu Leu Phe Thr Ile Leu Leu Phe Leu Leu Pro Thr Thr Ala 
    450                 455                 460                 


Leu Tyr Tyr Leu Val Phe Thr Leu Leu Arg Leu Leu Val Val Ala Val 
465                 470                 475                 480 


Gln Gly Leu Ile His Leu Leu Val Asp Leu Ile Asn Ser Leu Pro Leu 
                485                 490                 495     


Tyr Ser Leu Gly Leu Arg Leu Cys Arg Pro Tyr Arg Leu Ala Ala Gly 
            500                 505                 510         


Val Lys Phe Arg Val Leu Arg His Glu Ala Gly Arg Pro Leu Arg Leu 
        515                 520                 525             


Leu Met Gln Ile Asn Pro Leu Pro Tyr Ser Arg Val Val His Thr Tyr 
    530                 535                 540                 


Arg Leu Pro Ser Cys Gly Cys His Pro Lys His Ser Trp Gly Ala Leu 
545                 550                 555                 560 


Cys Arg Lys Leu Phe Leu Gly Glu Leu Ile Tyr Pro Trp Arg Gln Arg 
                565                 570                 575     


Gly Asp Lys Gln Asp 
            580     


<210>  1234
<211>  781
<212>  PRT
<213>  Human

<400>  1234

Met Ala Val Ala Glu Val Ser Arg Thr Cys Leu Leu Thr Val Arg Val 
1               5                   10                  15      


Leu Gln Ala His Arg Leu Pro Ser Lys Asp Leu Val Thr Pro Ser Asp 
            20                  25                  30          


Cys Tyr Val Thr Leu Trp Leu Pro Thr Ala Cys Ser His Arg Leu Gln 
        35                  40                  45              


Thr Arg Thr Val Lys Asn Ser Ser Ser Pro Val Trp Asn Gln Ser Phe 
    50                  55                  60                  


His Phe Arg Ile His Arg Gln Leu Lys Asn Val Met Glu Leu Lys Val 
65                  70                  75                  80  


Phe Asp Gln Asp Leu Val Thr Gly Asp Asp Pro Val Leu Ser Val Leu 
                85                  90                  95      


Phe Asp Ala Gly Thr Leu Arg Ala Gly Glu Phe Arg Arg Glu Ser Phe 
            100                 105                 110         


Ser Leu Ser Pro Gln Gly Glu Gly Arg Leu Glu Val Glu Phe Arg Leu 
        115                 120                 125             


Gln Ser Leu Ala Asp Arg Gly Glu Trp Leu Val Ser Asn Gly Val Leu 
    130                 135                 140                 


Val Ala Arg Glu Leu Ser Cys Leu His Val Gln Leu Glu Glu Thr Gly 
145                 150                 155                 160 


Asp Gln Lys Ser Ser Glu His Arg Val Gln Leu Val Val Pro Gly Ser 
                165                 170                 175     


Cys Glu Gly Pro Gln Glu Ala Ser Val Gly Thr Gly Thr Phe Arg Phe 
            180                 185                 190         


His Cys Pro Ala Cys Trp Glu Gln Glu Leu Ser Ile Arg Leu Gln Asp 
        195                 200                 205             


Ala Pro Glu Glu Gln Leu Lys Ala Pro Leu Ser Ala Leu Pro Ser Gly 
    210                 215                 220                 


Gln Val Val Arg Leu Val Phe Pro Thr Ser Gln Glu Pro Leu Met Arg 
225                 230                 235                 240 


Val Glu Leu Lys Lys Glu Ala Gly Leu Arg Glu Leu Ala Val Arg Leu 
                245                 250                 255     


Gly Phe Gly Pro Cys Ala Glu Glu Gln Ala Phe Leu Ser Arg Arg Lys 
            260                 265                 270         


Gln Val Val Ala Ala Ala Leu Arg Gln Ala Leu Gln Leu Asp Gly Asp 
        275                 280                 285             


Leu Gln Glu Asp Glu Ile Pro Val Val Ala Ile Met Ala Thr Gly Gly 
    290                 295                 300                 


Gly Ile Arg Ala Met Thr Ser Leu Tyr Gly Gln Leu Ala Gly Leu Lys 
305                 310                 315                 320 


Glu Leu Gly Leu Leu Asp Cys Val Ser Tyr Ile Thr Gly Ala Ser Gly 
                325                 330                 335     


Ser Thr Trp Ala Leu Ala Asn Leu Tyr Glu Asp Pro Glu Trp Ser Gln 
            340                 345                 350         


Lys Asp Leu Ala Gly Pro Thr Glu Leu Leu Lys Thr Gln Val Thr Lys 
        355                 360                 365             


Asn Lys Leu Gly Val Leu Ala Pro Ser Gln Leu Gln Arg Tyr Arg Gln 
    370                 375                 380                 


Glu Leu Ala Glu Arg Ala Arg Leu Gly Tyr Pro Ser Cys Phe Thr Asn 
385                 390                 395                 400 


Leu Trp Ala Leu Ile Asn Glu Ala Leu Leu His Asp Glu Pro His Asp 
                405                 410                 415     


His Lys Leu Ser Asp Gln Arg Glu Ala Leu Ser His Gly Gln Asn Pro 
            420                 425                 430         


Leu Pro Ile Tyr Cys Ala Leu Asn Thr Lys Gly Gln Ser Leu Thr Thr 
        435                 440                 445             


Phe Glu Phe Gly Glu Trp Cys Glu Phe Ser Pro Tyr Glu Val Gly Phe 
    450                 455                 460                 


Pro Lys Tyr Gly Ala Phe Ile Pro Ser Glu Leu Phe Gly Ser Glu Phe 
465                 470                 475                 480 


Phe Met Gly Gln Leu Met Lys Arg Leu Pro Glu Ser Arg Ile Cys Phe 
                485                 490                 495     


Leu Glu Gly Ile Trp Ser Asn Leu Tyr Ala Ala Asn Leu Gln Asp Ser 
            500                 505                 510         


Leu Tyr Trp Ala Ser Glu Pro Ser Gln Phe Trp Asp Arg Trp Val Arg 
        515                 520                 525             


Asn Gln Ala Asn Leu Asp Lys Glu Gln Val Pro Leu Leu Lys Ile Glu 
    530                 535                 540                 


Glu Pro Pro Ser Thr Ala Gly Arg Ile Ala Glu Phe Phe Thr Asp Leu 
545                 550                 555                 560 


Leu Thr Trp Arg Pro Leu Ala Gln Ala Thr His Asn Phe Leu Arg Gly 
                565                 570                 575     


Leu His Phe His Lys Asp Tyr Phe Gln His Pro His Phe Ser Thr Trp 
            580                 585                 590         


Lys Ala Thr Thr Leu Asp Gly Leu Pro Asn Gln Leu Thr Pro Ser Glu 
        595                 600                 605             


Pro His Leu Cys Leu Leu Asp Val Gly Tyr Leu Ile Asn Thr Ser Cys 
    610                 615                 620                 


Leu Pro Leu Leu Gln Pro Thr Arg Asp Val Asp Leu Ile Leu Ser Leu 
625                 630                 635                 640 


Asp Tyr Asn Leu His Gly Ala Phe Gln Gln Leu Gln Leu Leu Gly Arg 
                645                 650                 655     


Phe Cys Gln Glu Gln Gly Ile Pro Phe Pro Pro Ile Ser Pro Ser Pro 
            660                 665                 670         


Glu Glu Gln Leu Gln Pro Arg Glu Cys His Thr Phe Ser Asp Pro Thr 
        675                 680                 685             


Cys Pro Gly Ala Pro Ala Val Leu His Phe Pro Leu Val Ser Asp Ser 
    690                 695                 700                 


Phe Arg Glu Tyr Ser Ala Pro Gly Val Arg Arg Thr Pro Glu Glu Ala 
705                 710                 715                 720 


Ala Ala Gly Glu Val Asn Leu Ser Ser Ser Asp Ser Pro Tyr His Tyr 
                725                 730                 735     


Thr Lys Val Thr Tyr Ser Gln Glu Asp Val Asp Lys Leu Leu His Leu 
            740                 745                 750         


Thr His Tyr Asn Val Cys Asn Asn Gln Glu Gln Leu Leu Glu Ala Leu 
        755                 760                 765             


Arg Gln Ala Val Gln Arg Arg Arg Gln Arg Arg Pro His 
    770                 775                 780     


<210>  1235
<211>  251
<212>  PRT
<213>  Human

<400>  1235

Met Val Leu Ser Gly Val Asp Thr Val Leu Gly Lys Ser Glu Glu Trp 
1               5                   10                  15      


Ala Asp Asn His Leu Pro Leu Thr Asp Ala Glu Leu Ala Arg Ile Ala 
            20                  25                  30          


Thr Ser Leu Asp Gly Phe Asp Val Ala Ser Val Gln Gln Gln Arg Gln 
        35                  40                  45              


Glu Gln Ser Tyr Phe Val Arg Leu Gly Ser Leu Ser Glu Arg Leu Arg 
    50                  55                  60                  


Gln His Ala Tyr Glu His Ser Leu Gly Lys Leu Arg Ala Thr Lys Gln 
65                  70                  75                  80  


Arg Ala Gln Glu Ala Leu Leu Gln Leu Ser Gln Ala Leu Ser Leu Met 
                85                  90                  95      


Glu Thr Val Lys Gln Gly Val Asp Gln Lys Leu Val Glu Gly Gln Glu 
            100                 105                 110         


Lys Leu His Gln Met Trp Leu Ser Trp Asn Gln Lys Gln Leu Gln Gly 
        115                 120                 125             


Pro Glu Lys Glu Pro Pro Lys Pro Glu Gln Val Glu Ser Arg Ala Leu 
    130                 135                 140                 


Thr Met Phe Arg Asp Ile Ala Gln Gln Leu Gln Ala Thr Cys Thr Ser 
145                 150                 155                 160 


Leu Gly Ser Ser Ile Gln Gly Leu Pro Thr Asn Val Lys Asp Gln Val 
                165                 170                 175     


Gln Gln Ala Arg Arg Gln Val Glu Asp Leu Gln Ala Thr Phe Ser Ser 
            180                 185                 190         


Ile His Ser Phe Gln Asp Leu Ser Ser Ser Ile Leu Ala Gln Ser Arg 
        195                 200                 205             


Glu Arg Val Ala Ser Ala Arg Glu Ala Leu Asp His Met Val Glu Tyr 
    210                 215                 220                 


Val Ala Gln Asn Thr Pro Val Thr Trp Leu Val Gly Pro Phe Ala Pro 
225                 230                 235                 240 


Gly Ile Thr Glu Lys Ala Pro Glu Glu Lys Lys 
                245                 250     


<210>  1236
<211>  246
<212>  PRT
<213>  Human

<400>  1236

Met Ala Ala Pro Gly Pro Ala Leu Cys Leu Phe Asp Val Asp Gly Thr 
1               5                   10                  15      


Leu Thr Ala Pro Arg Gln Lys Ile Thr Lys Glu Met Asp Asp Phe Leu 
            20                  25                  30          


Gln Lys Leu Arg Gln Lys Ile Lys Ile Gly Val Val Gly Gly Ser Asp 
        35                  40                  45              


Phe Glu Lys Val Gln Glu Gln Leu Gly Asn Asp Val Val Glu Lys Tyr 
    50                  55                  60                  


Asp Tyr Val Phe Pro Glu Asn Gly Leu Val Ala Tyr Lys Asp Gly Lys 
65                  70                  75                  80  


Leu Leu Cys Arg Gln Asn Ile Gln Ser His Leu Gly Glu Ala Leu Ile 
                85                  90                  95      


Gln Asp Leu Ile Asn Tyr Cys Leu Ser Tyr Ile Ala Lys Ile Lys Leu 
            100                 105                 110         


Pro Lys Lys Arg Gly Thr Phe Ile Glu Phe Arg Asn Gly Met Leu Asn 
        115                 120                 125             


Val Ser Pro Ile Gly Arg Ser Cys Ser Gln Glu Glu Arg Ile Glu Phe 
    130                 135                 140                 


Tyr Glu Leu Asp Lys Lys Glu Asn Ile Arg Gln Lys Phe Val Ala Asp 
145                 150                 155                 160 


Leu Arg Lys Glu Phe Ala Gly Lys Gly Leu Thr Phe Ser Ile Gly Gly 
                165                 170                 175     


Gln Ile Ser Phe Asp Val Phe Pro Asp Gly Trp Asp Lys Arg Tyr Cys 
            180                 185                 190         


Leu Arg His Val Glu Asn Asp Gly Tyr Lys Thr Ile Tyr Phe Phe Gly 
        195                 200                 205             


Asp Lys Thr Met Pro Gly Gly Asn Asp His Glu Ile Phe Thr Asp Pro 
    210                 215                 220                 


Arg Thr Met Gly Tyr Ser Val Thr Ala Pro Glu Asp Thr Arg Arg Ile 
225                 230                 235                 240 


Cys Glu Leu Leu Phe Ser 
                245     


<210>  1237
<211>  301
<212>  PRT
<213>  Human

<400>  1237

Met Ala Thr Thr Lys Arg Val Leu Tyr Val Gly Gly Leu Ala Glu Glu 
1               5                   10                  15      


Val Asp Asp Lys Val Leu His Ala Ala Phe Ile Pro Phe Gly Asp Ile 
            20                  25                  30          


Thr Asp Ile Gln Ile Pro Leu Asp Tyr Glu Thr Glu Lys His Arg Gly 
        35                  40                  45              


Phe Ala Phe Val Glu Phe Glu Leu Ala Glu Asp Ala Ala Ala Ala Ile 
    50                  55                  60                  


Asp Asn Met Asn Glu Ser Glu Leu Phe Gly Arg Thr Ile Arg Val Asn 
65                  70                  75                  80  


Leu Ala Lys Pro Met Arg Ile Lys Glu Gly Ser Ser Arg Pro Val Trp 
                85                  90                  95      


Ser Asp Asp Asp Trp Leu Lys Lys Phe Ser Gly Lys Thr Leu Glu Glu 
            100                 105                 110         


Asn Lys Glu Glu Glu Gly Ser Glu Pro Pro Lys Ala Glu Thr Gln Glu 
        115                 120                 125             


Gly Glu Pro Ile Ala Lys Lys Ala Arg Ser Asn Pro Gln Val Tyr Met 
    130                 135                 140                 


Asp Ile Lys Ile Gly Asn Lys Pro Ala Gly Arg Ile Gln Met Leu Leu 
145                 150                 155                 160 


Arg Ser Asp Val Val Pro Met Thr Ala Glu Asn Phe Arg Cys Leu Cys 
                165                 170                 175     


Thr His Glu Lys Gly Phe Gly Phe Lys Gly Ser Ser Phe His Arg Ile 
            180                 185                 190         


Ile Pro Gln Phe Met Cys Gln Gly Gly Asp Phe Thr Asn His Asn Gly 
        195                 200                 205             


Thr Gly Gly Lys Ser Ile Tyr Gly Lys Lys Phe Asp Asp Glu Asn Phe 
    210                 215                 220                 


Ile Leu Lys His Thr Gly Pro Gly Leu Leu Ser Met Ala Asn Ser Gly 
225                 230                 235                 240 


Pro Asn Thr Asn Gly Ser Gln Phe Phe Leu Thr Cys Asp Lys Thr Asp 
                245                 250                 255     


Trp Leu Asp Gly Lys His Val Val Phe Gly Glu Val Thr Glu Gly Leu 
            260                 265                 270         


Asp Val Leu Arg Gln Ile Glu Ala Gln Gly Ser Lys Asp Gly Lys Pro 
        275                 280                 285             


Lys Gln Lys Val Ile Ile Ala Asp Cys Gly Glu Tyr Val 
    290                 295                 300     


<210>  1238
<211>  239
<212>  PRT
<213>  Human

<400>  1238

Met Ala Ala Thr Leu Leu Ala Ala Arg Gly Ala Gly Pro Ala Pro Ala 
1               5                   10                  15      


Trp Gly Pro Glu Ala Phe Thr Pro Asp Trp Glu Ser Arg Glu Val Ser 
            20                  25                  30          


Thr Gly Thr Thr Ile Met Ala Val Gln Phe Asp Gly Gly Val Val Leu 
        35                  40                  45              


Gly Ala Asp Ser Arg Thr Thr Thr Gly Ser Tyr Ile Ala Asn Arg Val 
    50                  55                  60                  


Thr Asp Lys Leu Thr Pro Ile His Asp Arg Ile Phe Cys Cys Arg Ser 
65                  70                  75                  80  


Gly Ser Ala Ala Asp Thr Gln Ala Val Ala Asp Ala Val Thr Tyr Gln 
                85                  90                  95      


Leu Gly Phe His Ser Ile Glu Leu Asn Glu Pro Pro Leu Val His Thr 
            100                 105                 110         


Ala Ala Ser Leu Phe Lys Glu Met Cys Tyr Arg Tyr Arg Glu Asp Leu 
        115                 120                 125             


Met Ala Gly Ile Ile Ile Ala Gly Trp Asp Pro Gln Glu Gly Gly Gln 
    130                 135                 140                 


Val Tyr Ser Val Pro Met Gly Gly Met Met Val Arg Gln Ser Phe Ala 
145                 150                 155                 160 


Ile Gly Gly Ser Gly Ser Ser Tyr Ile Tyr Gly Tyr Val Asp Ala Thr 
                165                 170                 175     


Tyr Arg Glu Gly Met Thr Lys Glu Glu Cys Leu Gln Phe Thr Ala Asn 
            180                 185                 190         


Ala Leu Ala Leu Ala Met Glu Arg Asp Gly Ser Ser Gly Gly Val Ile 
        195                 200                 205             


Arg Leu Ala Ala Ile Ala Glu Ser Gly Val Glu Arg Gln Val Leu Leu 
    210                 215                 220                 


Gly Asp Gln Ile Pro Lys Phe Ala Val Ala Thr Leu Pro Pro Ala 
225                 230                 235                 


<210>  1239
<211>  306
<212>  PRT
<213>  Human

<400>  1239

Met Ser Leu Lys Leu Gln Ala Ser Asn Val Thr Asn Lys Asn Asp Pro 
1               5                   10                  15      


Lys Ser Ile Asn Ser Arg Val Phe Ile Gly Asn Leu Asn Thr Ala Leu 
            20                  25                  30          


Val Lys Lys Ser Asp Val Glu Thr Ile Phe Ser Lys Tyr Gly Arg Val 
        35                  40                  45              


Ala Gly Cys Ser Val His Lys Gly Tyr Ala Phe Val Gln Tyr Ser Asn 
    50                  55                  60                  


Glu Arg His Ala Arg Ala Ala Val Leu Gly Glu Asn Gly Arg Val Leu 
65                  70                  75                  80  


Ala Gly Gln Thr Leu Asp Ile Asn Met Ala Gly Glu Pro Lys Pro Asp 
                85                  90                  95      


Arg Pro Lys Gly Leu Lys Arg Ala Ala Ser Ala Ile Tyr Ser Gly Tyr 
            100                 105                 110         


Ile Phe Asp Tyr Asp Tyr Tyr Arg Asp Asp Phe Tyr Asp Arg Leu Phe 
        115                 120                 125             


Asp Tyr Arg Gly Arg Leu Ser Pro Val Pro Val Pro Arg Ala Val Pro 
    130                 135                 140                 


Val Lys Arg Pro Arg Val Thr Val Pro Leu Val Arg Arg Val Lys Thr 
145                 150                 155                 160 


Asn Val Pro Val Lys Leu Phe Ala Arg Ser Thr Ala Val Thr Thr Ser 
                165                 170                 175     


Ser Ala Lys Ile Lys Leu Lys Ser Ser Glu Leu Gln Ala Ile Lys Thr 
            180                 185                 190         


Glu Leu Thr Gln Ile Lys Ser Asn Ile Asp Ala Leu Leu Ser Arg Leu 
        195                 200                 205             


Glu Gln Ile Ala Ala Glu Gln Lys Ala Asn Pro Asp Gly Lys Lys Lys 
    210                 215                 220                 


Gly Asp Gly Gly Gly Ala Gly Gly Gly Gly Gly Gly Gly Gly Ser Gly 
225                 230                 235                 240 


Gly Gly Gly Ser Gly Gly Gly Gly Gly Gly Gly Ser Ser Arg Pro Pro 
                245                 250                 255     


Ala Pro Gln Glu Asn Thr Thr Ser Glu Ala Gly Leu Pro Gln Gly Glu 
            260                 265                 270         


Ala Arg Thr Arg Asp Asp Gly Asp Glu Glu Gly Leu Leu Thr His Ser 
        275                 280                 285             


Glu Glu Glu Leu Glu His Ser Gln Asp Thr Asp Ala Asp Asp Gly Ala 
    290                 295                 300                 


Leu Gln 
305     


<210>  1240
<211>  852
<212>  PRT
<213>  Human

<400>  1240

Met Glu Tyr Glu Arg Arg Gly Gly Arg Gly Asp Arg Thr Gly Arg Tyr 
1               5                   10                  15      


Gly Ala Thr Asp Arg Ser Gln Asp Asp Gly Gly Glu Asn Arg Ser Arg 
            20                  25                  30          


Asp His Asp Tyr Arg Asp Met Asp Tyr Arg Ser Tyr Pro Arg Glu Tyr 
        35                  40                  45              


Gly Ser Gln Glu Gly Lys His Asp Tyr Asp Asp Ser Ser Glu Glu Gln 
    50                  55                  60                  


Ser Ala Glu Ile Arg Gly Gln Leu Gln Ser His Gly Val Gln Ala Arg 
65                  70                  75                  80  


Glu Val Arg Leu Met Arg Asn Lys Ser Ser Gly Gln Ser Arg Gly Phe 
                85                  90                  95      


Ala Phe Val Glu Phe Ser His Leu Gln Asp Ala Thr Arg Trp Met Glu 
            100                 105                 110         


Ala Asn Gln His Ser Leu Asn Ile Leu Gly Gln Lys Val Ser Met His 
        115                 120                 125             


Tyr Ser Asp Pro Lys Pro Lys Ile Asn Glu Asp Trp Leu Cys Asn Lys 
    130                 135                 140                 


Cys Gly Val Gln Asn Phe Lys Arg Arg Glu Lys Cys Phe Lys Cys Gly 
145                 150                 155                 160 


Val Pro Lys Ser Glu Ala Glu Gln Lys Leu Pro Leu Gly Thr Arg Leu 
                165                 170                 175     


Asp Gln Gln Thr Leu Pro Leu Gly Gly Arg Glu Leu Ser Gln Gly Leu 
            180                 185                 190         


Leu Pro Leu Pro Gln Pro Tyr Gln Ala Gln Gly Val Leu Ala Ser Gln 
        195                 200                 205             


Ala Leu Ser Gln Gly Ser Glu Pro Ser Ser Glu Asn Ala Asn Asp Thr 
    210                 215                 220                 


Ile Ile Leu Arg Asn Leu Asn Pro His Ser Thr Met Asp Ser Ile Leu 
225                 230                 235                 240 


Gly Ala Leu Ala Pro Tyr Ala Val Leu Ser Ser Ser Asn Val Arg Val 
                245                 250                 255     


Ile Lys Asp Lys Gln Thr Gln Leu Asn Arg Gly Phe Ala Phe Ile Gln 
            260                 265                 270         


Leu Ser Thr Ile Glu Ala Ala Gln Leu Leu Gln Ile Leu Gln Ala Leu 
        275                 280                 285             


His Pro Pro Leu Thr Ile Asp Gly Lys Thr Ile Asn Val Glu Phe Ala 
    290                 295                 300                 


Lys Gly Ser Lys Arg Asp Met Ala Ser Asn Glu Gly Ser Arg Ile Ser 
305                 310                 315                 320 


Ala Ala Ser Val Ala Ser Thr Ala Ile Ala Ala Ala Gln Trp Ala Ile 
                325                 330                 335     


Ser Gln Ala Ser Gln Gly Gly Glu Gly Thr Trp Ala Thr Ser Glu Glu 
            340                 345                 350         


Pro Pro Val Asp Tyr Ser Tyr Tyr Gln Gln Asp Glu Gly Tyr Gly Asn 
        355                 360                 365             


Ser Gln Gly Thr Glu Ser Ser Leu Tyr Ala His Gly Tyr Leu Lys Gly 
    370                 375                 380                 


Thr Lys Gly Pro Gly Ile Thr Gly Thr Lys Gly Asp Pro Thr Gly Ala 
385                 390                 395                 400 


Gly Pro Glu Ala Ser Leu Glu Pro Gly Ala Asp Ser Val Ser Met Gln 
                405                 410                 415     


Ala Phe Ser Arg Ala Gln Pro Gly Ala Ala Pro Gly Ile Tyr Gln Gln 
            420                 425                 430         


Ser Ala Glu Ala Ser Ser Ser Gln Gly Thr Ala Ala Asn Ser Gln Ser 
        435                 440                 445             


Tyr Thr Ile Met Ser Pro Ala Val Leu Lys Ser Glu Leu Gln Ser Pro 
    450                 455                 460                 


Thr His Pro Ser Ser Ala Leu Pro Pro Ala Thr Ser Pro Thr Ala Gln 
465                 470                 475                 480 


Glu Ser Tyr Ser Gln Tyr Pro Val Pro Asp Val Ser Thr Tyr Gln Tyr 
                485                 490                 495     


Asp Glu Thr Ser Gly Tyr Tyr Tyr Asp Pro Gln Thr Gly Leu Tyr Tyr 
            500                 505                 510         


Asp Pro Asn Ser Gln Tyr Tyr Tyr Asn Ala Gln Ser Gln Gln Tyr Leu 
        515                 520                 525             


Tyr Trp Asp Gly Glu Arg Arg Thr Tyr Val Pro Ala Leu Glu Gln Ser 
    530                 535                 540                 


Ala Asp Gly His Lys Glu Thr Gly Ala Pro Ser Lys Glu Gly Lys Glu 
545                 550                 555                 560 


Lys Lys Glu Lys His Lys Thr Lys Thr Ala Gln Gln Ile Ala Lys Asp 
                565                 570                 575     


Met Glu Arg Trp Ala Arg Ser Leu Asn Lys Gln Lys Glu Asn Phe Lys 
            580                 585                 590         


Asn Ser Phe Gln Pro Ile Ser Ser Leu Arg Asp Asp Glu Arg Arg Glu 
        595                 600                 605             


Ser Ala Thr Ala Asp Ala Gly Tyr Ala Ile Leu Glu Lys Lys Gly Ala 
    610                 615                 620                 


Leu Ala Glu Arg Gln His Thr Ser Met Asp Leu Pro Lys Leu Ala Ser 
625                 630                 635                 640 


Asp Asp Arg Pro Ser Pro Pro Arg Gly Leu Val Ala Ala Tyr Ser Gly 
                645                 650                 655     


Glu Ser Asp Ser Glu Glu Glu Gln Glu Arg Gly Gly Pro Glu Arg Glu 
            660                 665                 670         


Glu Lys Leu Thr Asp Trp Gln Lys Leu Ala Cys Leu Leu Cys Arg Arg 
        675                 680                 685             


Gln Phe Pro Ser Lys Glu Ala Leu Ile Arg His Gln Gln Leu Ser Gly 
    690                 695                 700                 


Leu His Lys Gln Asn Leu Glu Ile His Arg Arg Ala His Leu Ser Glu 
705                 710                 715                 720 


Asn Glu Leu Glu Ala Leu Glu Lys Asn Asp Met Glu Gln Met Lys Tyr 
                725                 730                 735     


Arg Asp Arg Ala Ala Glu Arg Arg Glu Lys Tyr Gly Ile Pro Glu Pro 
            740                 745                 750         


Pro Glu Pro Lys Arg Arg Lys Tyr Gly Gly Ile Ser Thr Ala Ser Val 
        755                 760                 765             


Asp Phe Glu Gln Pro Thr Arg Asp Gly Leu Gly Ser Asp Asn Ile Gly 
    770                 775                 780                 


Ser Arg Met Leu Gln Ala Met Gly Trp Lys Glu Gly Ser Gly Leu Gly 
785                 790                 795                 800 


Arg Lys Lys Gln Gly Ile Val Thr Pro Ile Glu Ala Gln Thr Arg Val 
                805                 810                 815     


Arg Gly Ser Gly Leu Gly Ala Arg Gly Ser Ser Tyr Gly Val Thr Ser 
            820                 825                 830         


Thr Glu Ser Tyr Lys Glu Thr Leu His Lys Thr Met Val Thr Arg Phe 
        835                 840                 845             


Asn Glu Ala Gln 
    850         


<210>  1241
<211>  777
<212>  PRT
<213>  Human

<400>  1241

Met Ser Arg Leu Ile Val Lys Asn Leu Pro Asn Gly Met Lys Glu Glu 
1               5                   10                  15      


Arg Phe Arg Gln Leu Phe Ala Ala Phe Gly Thr Leu Thr Asp Cys Ser 
            20                  25                  30          


Leu Lys Phe Thr Lys Asp Gly Lys Phe Arg Lys Phe Gly Phe Ile Gly 
        35                  40                  45              


Phe Lys Ser Glu Glu Glu Ala Gln Lys Ala Gln Lys His Phe Asn Lys 
    50                  55                  60                  


Ser Phe Ile Asp Thr Ser Arg Ile Thr Val Glu Phe Cys Lys Ser Phe 
65                  70                  75                  80  


Gly Asp Pro Ala Lys Pro Arg Ala Trp Ser Lys His Ala Gln Lys Pro 
                85                  90                  95      


Ser Gln Pro Lys Gln Pro Pro Lys Asp Ser Thr Thr Pro Glu Ile Lys 
            100                 105                 110         


Lys Asp Glu Lys Lys Lys Lys Val Ala Gly Gln Leu Glu Lys Leu Lys 
        115                 120                 125             


Glu Asp Thr Glu Phe Gln Glu Phe Leu Ser Val His Gln Arg Arg Ala 
    130                 135                 140                 


Gln Ala Ala Thr Trp Ala Asn Asp Gly Leu Asp Ala Glu Pro Ser Lys 
145                 150                 155                 160 


Gly Lys Ser Lys Pro Ala Ser Asp Tyr Leu Asn Phe Asp Ser Asp Ser 
                165                 170                 175     


Gly Gln Glu Ser Glu Glu Glu Gly Ala Gly Glu Asp Leu Glu Glu Glu 
            180                 185                 190         


Ala Ser Leu Glu Pro Lys Ala Ala Val Gln Lys Glu Leu Ser Asp Met 
        195                 200                 205             


Asp Tyr Leu Lys Ser Lys Met Val Lys Ala Gly Ser Ser Ser Ser Ser 
    210                 215                 220                 


Glu Glu Glu Glu Ser Glu Asp Glu Ala Val His Cys Asp Glu Gly Ser 
225                 230                 235                 240 


Glu Ala Glu Glu Glu Asp Ser Ser Ala Thr Pro Val Leu Gln Glu Arg 
                245                 250                 255     


Asp Ser Lys Gly Ala Gly Gln Glu Gln Gly Met Pro Ala Gly Lys Lys 
            260                 265                 270         


Arg Pro Pro Glu Ala Arg Ala Glu Thr Glu Lys Pro Ala Asn Gln Lys 
        275                 280                 285             


Glu Pro Thr Thr Cys His Thr Thr Val Lys Leu Arg Gly Ala Pro Phe 
    290                 295                 300                 


Asn Val Thr Glu Lys Asn Val Met Glu Phe Leu Ala Pro Leu Lys Pro 
305                 310                 315                 320 


Val Ala Ile Arg Ile Val Arg Asn Ala His Gly Asn Lys Thr Gly Tyr 
                325                 330                 335     


Ile Phe Val Asp Phe Ser Asn Glu Glu Glu Val Lys Gln Ala Leu Lys 
            340                 345                 350         


Cys Asn Arg Glu Tyr Met Gly Glu Thr Lys Gly Ser Val Ala Val Arg 
        355                 360                 365             


Val Ala Leu Gly Glu Thr Gln Leu Val Gln Glu Val Arg Arg Phe Leu 
    370                 375                 380                 


Ile Asp Asn Gly Val Ser Leu Asp Ser Phe Ser Gln Ala Ala Ala Glu 
385                 390                 395                 400 


Arg Ser Lys Thr Val Ile Leu Val Lys Asn Leu Pro Ala Gly Thr Leu 
                405                 410                 415     


Ala Ala Glu Leu Gln Glu Thr Phe Gly His Phe Gly Ser Leu Gly Arg 
            420                 425                 430         


Val Leu Leu Pro Glu Gly Gly Ile Thr Ala Ile Val Glu Phe Leu Glu 
        435                 440                 445             


Pro Leu Glu Ala Arg Lys Ala Phe Arg His Leu Ala Tyr Ser Lys Phe 
    450                 455                 460                 


His His Val Pro Leu Tyr Leu Glu Trp Ala Pro Val Gly Val Phe Ser 
465                 470                 475                 480 


Ser Thr Ala Pro Gln Lys Lys Lys Leu Gln Asp Thr Pro Ser Glu Pro 
                485                 490                 495     


Met Glu Lys Asp Pro Ala Glu Pro Glu Thr Val Pro Asp Gly Glu Thr 
            500                 505                 510         


Pro Glu Asp Glu Asn Pro Thr Glu Glu Gly Ala Asp Asn Ser Ser Ala 
        515                 520                 525             


Lys Met Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Ser Leu 
    530                 535                 540                 


Pro Gly Cys Thr Leu Phe Ile Lys Asn Leu Asn Phe Asp Thr Thr Glu 
545                 550                 555                 560 


Glu Lys Leu Lys Glu Val Phe Ser Lys Val Gly Thr Val Lys Ser Cys 
                565                 570                 575     


Ser Ile Ser Lys Lys Lys Asn Lys Ala Gly Val Leu Leu Ser Met Gly 
            580                 585                 590         


Phe Gly Phe Val Glu Tyr Arg Lys Pro Glu Gln Ala Gln Lys Ala Leu 
        595                 600                 605             


Lys Gln Leu Gln Gly His Val Val Asp Gly His Lys Leu Glu Val Arg 
    610                 615                 620                 


Ile Ser Glu Arg Ala Thr Lys Pro Ala Val Thr Leu Ala Arg Lys Lys 
625                 630                 635                 640 


Gln Val Pro Arg Lys Gln Thr Thr Ser Lys Ile Leu Val Arg Asn Ile 
                645                 650                 655     


Pro Phe Gln Ala His Ser Arg Glu Ile Arg Glu Leu Phe Ser Thr Phe 
            660                 665                 670         


Gly Glu Leu Lys Thr Val Arg Leu Pro Lys Lys Met Thr Gly Thr Gly 
        675                 680                 685             


Thr His Arg Gly Phe Gly Phe Val Asp Phe Leu Thr Lys Gln Asp Ala 
    690                 695                 700                 


Lys Arg Ala Phe Asn Ala Leu Cys His Ser Thr His Leu Tyr Gly Arg 
705                 710                 715                 720 


Arg Leu Val Leu Glu Trp Ala Asp Ser Glu Val Thr Leu Gln Ala Leu 
                725                 730                 735     


Arg Arg Lys Thr Ala Ala His Phe His Glu Pro Pro Lys Lys Lys Arg 
            740                 745                 750         


Ser Val Val Leu Asp Glu Ile Leu Glu Gln Leu Glu Gly Ser Asp Ser 
        755                 760                 765             


Asp Ser Glu Glu Gln Thr Leu Gln Leu 
    770                 775         


<210>  1242
<211>  1738
<212>  PRT
<213>  Human

<400>  1242

Met Lys Ser Arg Pro Thr Lys Gln Lys Leu Lys Gln Arg Gly Ile Leu 
1               5                   10                  15      


Lys Glu Arg Val Phe Gly Cys Asp Leu Gly Glu His Leu Leu Asn Ser 
            20                  25                  30          


Gly Phe Glu Val Pro Gln Val Leu Gln Ser Cys Thr Ala Phe Ile Glu 
        35                  40                  45              


Arg Tyr Gly Ile Val Asp Gly Ile Tyr Arg Leu Ser Gly Val Ala Ser 
    50                  55                  60                  


Asn Ile Gln Arg Leu Arg His Glu Phe Asp Ser Glu His Val Pro Asp 
65                  70                  75                  80  


Leu Thr Lys Glu Pro Tyr Val Gln Asp Ile His Ser Val Gly Ser Leu 
                85                  90                  95      


Cys Lys Leu Tyr Phe Arg Glu Leu Pro Asn Pro Leu Leu Thr Tyr Gln 
            100                 105                 110         


Leu Tyr Glu Lys Phe Ser Asp Ala Val Ser Ala Ala Thr Asp Glu Glu 
        115                 120                 125             


Arg Leu Ile Lys Ile His Asp Val Ile Gln Gln Leu Pro Pro Pro His 
    130                 135                 140                 


Tyr Arg Thr Leu Glu Phe Leu Met Arg His Leu Ser Leu Leu Ala Asp 
145                 150                 155                 160 


Tyr Cys Ser Ile Thr Asn Met His Ala Lys Asn Leu Ala Ile Val Trp 
                165                 170                 175     


Ala Pro Asn Leu Leu Arg Ser Lys Gln Ile Glu Ser Ala Cys Phe Ser 
            180                 185                 190         


Gly Thr Ala Ala Phe Met Glu Val Arg Ile Gln Ser Val Val Val Glu 
        195                 200                 205             


Phe Ile Leu Asn His Val Asp Val Leu Phe Ser Gly Arg Ile Ser Met 
    210                 215                 220                 


Ala Met Gln Glu Gly Ala Ala Ser Leu Ser Arg Pro Lys Ser Leu Leu 
225                 230                 235                 240 


Val Ser Ser Pro Ser Thr Lys Leu Leu Thr Leu Glu Glu Ala Gln Ala 
                245                 250                 255     


Arg Thr Gln Ala Gln Val Asn Ser Pro Ile Val Thr Glu Asn Lys Tyr 
            260                 265                 270         


Ile Glu Val Gly Glu Gly Pro Ala Ala Leu Gln Gly Lys Phe His Thr 
        275                 280                 285             


Ile Ile Glu Phe Pro Leu Glu Arg Lys Arg Pro Gln Asn Lys Met Lys 
    290                 295                 300                 


Lys Ser Pro Val Gly Ser Trp Arg Ser Phe Phe Asn Leu Gly Lys Ser 
305                 310                 315                 320 


Ser Ser Val Ser Lys Arg Lys Leu Gln Arg Asn Glu Ser Glu Pro Ser 
                325                 330                 335     


Glu Met Lys Ala Met Ala Leu Lys Gly Gly Arg Ala Glu Gly Thr Leu 
            340                 345                 350         


Arg Ser Ala Lys Ser Glu Glu Ser Leu Thr Ser Leu His Ala Val Asp 
        355                 360                 365             


Gly Asp Ser Lys Leu Phe Arg Pro Arg Arg Pro Arg Ser Ser Ser Asp 
    370                 375                 380                 


Ala Leu Ser Ala Ser Phe Asn Gly Glu Met Leu Gly Asn Arg Cys Asn 
385                 390                 395                 400 


Ser Tyr Asp Asn Leu Pro His Asp Asn Glu Ser Glu Glu Glu Gly Gly 
                405                 410                 415     


Leu Leu His Ile Pro Ala Leu Met Ser Pro His Ser Ala Glu Asp Val 
            420                 425                 430         


Asp Leu Ser Pro Pro Asp Ile Gly Val Ala Ser Leu Asp Phe Asp Pro 
        435                 440                 445             


Met Ser Phe Gln Cys Ser Pro Pro Lys Ala Glu Ser Glu Cys Leu Glu 
    450                 455                 460                 


Ser Gly Ala Ser Phe Leu Asp Ser Pro Gly Tyr Ser Lys Asp Lys Pro 
465                 470                 475                 480 


Ser Ala Asn Lys Lys Asp Ala Glu Thr Gly Ser Ser Gln Cys Gln Thr 
                485                 490                 495     


Pro Gly Ser Thr Ala Ser Ser Glu Pro Val Ser Pro Leu Gln Glu Lys 
            500                 505                 510         


Leu Ser Pro Phe Phe Thr Leu Asp Leu Ser Pro Thr Glu Asp Lys Ser 
        515                 520                 525             


Ser Lys Pro Ser Ser Phe Thr Glu Lys Val Val Tyr Ala Phe Ser Pro 
    530                 535                 540                 


Lys Ile Gly Arg Lys Leu Ser Lys Ser Pro Ser Met Ser Ile Ser Glu 
545                 550                 555                 560 


Pro Ile Ser Val Thr Leu Pro Pro Arg Val Ser Glu Val Ile Gly Thr 
                565                 570                 575     


Val Ser Asn Thr Thr Ala Gln Asn Ala Ser Ser Ser Thr Trp Asp Lys 
            580                 585                 590         


Cys Val Glu Glu Arg Asp Ala Thr Asn Arg Ser Pro Thr Gln Ile Val 
        595                 600                 605             


Lys Met Lys Thr Asn Glu Thr Val Ala Gln Glu Ala Tyr Glu Ser Glu 
    610                 615                 620                 


Val Gln Pro Leu Asp Gln Val Ala Ala Glu Glu Val Glu Leu Pro Gly 
625                 630                 635                 640 


Lys Glu Asp Gln Ser Val Ser Ser Ser Gln Ser Lys Ala Val Ala Ser 
                645                 650                 655     


Gly Gln Thr Gln Thr Gly Ala Val Thr His Asp Pro Pro Gln Asp Ser 
            660                 665                 670         


Val Pro Val Ser Ser Val Ser Leu Ile Pro Pro Pro Pro Pro Pro Lys 
        675                 680                 685             


Asn Val Ala Arg Met Leu Ala Leu Ala Leu Ala Glu Ser Ala Gln Gln 
    690                 695                 700                 


Ala Ser Thr Gln Ser Leu Lys Arg Pro Gly Thr Ser Gln Ala Gly Tyr 
705                 710                 715                 720 


Thr Asn Tyr Gly Asp Ile Ala Val Ala Thr Thr Glu Asp Asn Leu Ser 
                725                 730                 735     


Ser Ser Tyr Ser Ala Val Ala Leu Asp Lys Ala Tyr Phe Gln Thr Asp 
            740                 745                 750         


Arg Pro Ala Glu Gln Phe His Leu Gln Asn Asn Ala Pro Gly Asn Cys 
        755                 760                 765             


Asp His Pro Leu Pro Glu Thr Thr Ala Thr Gly Asp Pro Thr His Ser 
    770                 775                 780                 


Asn Thr Thr Glu Ser Gly Glu Gln His His Gln Val Asp Leu Thr Gly 
785                 790                 795                 800 


Asn Gln Pro His Gln Ala Tyr Leu Ser Gly Asp Pro Glu Lys Ala Arg 
                805                 810                 815     


Ile Thr Ser Val Pro Leu Asp Ser Glu Lys Ser Asp Asp His Val Ser 
            820                 825                 830         


Phe Pro Glu Asp Gln Ser Gly Lys Asn Ser Met Pro Thr Val Ser Phe 
        835                 840                 845             


Leu Asp Gln Asp Gln Ser Pro Pro Arg Phe Tyr Ser Gly Asp Gln Pro 
    850                 855                 860                 


Pro Ser Tyr Leu Gly Ala Ser Val Asp Lys Leu His His Pro Leu Glu 
865                 870                 875                 880 


Phe Ala Asp Lys Ser Pro Thr Pro Pro Asn Leu Pro Ser Asp Lys Ile 
                885                 890                 895     


Tyr Pro Pro Ser Gly Ser Pro Glu Glu Asn Thr Ser Thr Ala Thr Met 
            900                 905                 910         


Thr Tyr Met Thr Thr Thr Pro Ala Thr Ala Gln Met Ser Thr Lys Glu 
        915                 920                 925             


Ala Ser Trp Asp Val Ala Glu Gln Pro Thr Thr Ala Asp Phe Ala Ala 
    930                 935                 940                 


Ala Thr Leu Gln Arg Thr His Arg Thr Asn Arg Pro Leu Pro Pro Pro 
945                 950                 955                 960 


Pro Ser Gln Arg Ser Ala Glu Gln Pro Pro Val Val Gly Gln Val Gln 
                965                 970                 975     


Ala Ala Thr Asn Ile Gly Leu Asn Asn Ser His Lys Val Gln Gly Val 
            980                 985                 990         


Val Pro Val Pro Glu Arg Pro Pro  Glu Pro Arg Ala Met  Asp Asp Pro 
        995                 1000                 1005             


Ala Ser  Ala Phe Ile Ser Asp  Ser Gly Ala Ala Ala  Ala Gln Cys 
    1010                 1015                 1020             


Pro Met  Ala Thr Ala Val Gln  Pro Gly Leu Pro Glu  Lys Val Arg 
    1025                 1030                 1035             


Asp Gly  Ala Arg Val Pro Leu  Leu His Leu Arg Ala  Glu Ser Val 
    1040                 1045                 1050             


Pro Ala  His Pro Cys Gly Phe  Pro Ala Pro Leu Pro  Pro Thr Arg 
    1055                 1060                 1065             


Met Met  Glu Ser Lys Met Ile  Ala Ala Ile His Ser  Ser Ser Ala 
    1070                 1075                 1080             


Asp Ala  Thr Ser Ser Ser Asn  Tyr His Ser Phe Val  Thr Ala Ser 
    1085                 1090                 1095             


Ser Thr  Ser Val Asp Asp Ala  Leu Pro Leu Pro Leu  Pro Val Pro 
    1100                 1105                 1110             


Gln Pro  Lys His Ala Ser Gln  Lys Thr Val Tyr Ser  Ser Phe Ala 
    1115                 1120                 1125             


Arg Pro  Asp Val Thr Thr Glu  Pro Phe Gly Pro Asp  Asn Cys Leu 
    1130                 1135                 1140             


His Phe  Asn Met Thr Pro Asn  Cys Gln Tyr Arg Pro  Gln Ser Val 
    1145                 1150                 1155             


Pro Pro  His His Asn Lys Leu  Glu Gln His Gln Val  Tyr Gly Ala 
    1160                 1165                 1170             


Arg Ser  Glu Pro Pro Ala Ser  Met Gly Leu Arg Tyr  Asn Thr Tyr 
    1175                 1180                 1185             


Val Ala  Pro Gly Arg Asn Ala  Ser Gly His His Ser  Lys Pro Cys 
    1190                 1195                 1200             


Ser Arg  Val Glu Tyr Val Ser  Ser Leu Ser Ser Ser  Val Arg Asn 
    1205                 1210                 1215             


Thr Cys  Tyr Pro Glu Asp Ile  Pro Pro Tyr Pro Thr  Ile Arg Arg 
    1220                 1225                 1230             


Val Gln  Ser Leu His Ala Pro  Pro Ser Ser Met Ile  Arg Ser Val 
    1235                 1240                 1245             


Pro Ile  Ser Arg Thr Glu Val  Pro Pro Asp Asp Glu  Pro Ala Tyr 
    1250                 1255                 1260             


Cys Pro  Arg Pro Leu Tyr Gln  Tyr Lys Pro Tyr Gln  Ser Ser Gln 
    1265                 1270                 1275             


Ala Arg  Ser Asp Tyr His Val  Thr Gln Leu Gln Pro  Tyr Phe Glu 
    1280                 1285                 1290             


Asn Gly  Arg Val His Tyr Arg  Tyr Ser Pro Tyr Ser  Ser Ser Ser 
    1295                 1300                 1305             


Ser Ser  Tyr Tyr Ser Pro Asp  Gly Ala Leu Cys Asp  Val Asp Ala 
    1310                 1315                 1320             


Tyr Gly  Thr Val Gln Leu Arg  Pro Leu His Arg Leu  Pro Asn Arg 
    1325                 1330                 1335             


Asp Phe  Ala Phe Tyr Asn Pro  Arg Leu Gln Gly Lys  Ser Leu Tyr 
    1340                 1345                 1350             


Ser Tyr  Ala Gly Leu Ala Pro  Arg Pro Arg Ala Asn  Val Thr Gly 
    1355                 1360                 1365             


Tyr Phe  Ser Pro Asn Asp His  Asn Val Val Ser Met  Pro Pro Ala 
    1370                 1375                 1380             


Ala Asp  Val Lys His Thr Tyr  Thr Ser Trp Asp Leu  Glu Asp Met 
    1385                 1390                 1395             


Glu Lys  Tyr Arg Met Gln Ser  Ile Arg Arg Glu Ser  Arg Ala Arg 
    1400                 1405                 1410             


Gln Lys  Val Lys Gly Pro Val  Met Ser Gln Tyr Asp  Asn Met Thr 
    1415                 1420                 1425             


Pro Ala  Val Gln Asp Asp Leu  Gly Gly Ile Tyr Val  Ile His Leu 
    1430                 1435                 1440             


Arg Ser  Lys Ser Asp Pro Gly  Lys Thr Gly Leu Leu  Ser Val Ala 
    1445                 1450                 1455             


Glu Gly  Lys Glu Ser Arg His  Ala Ala Lys Ala Ile  Ser Pro Glu 
    1460                 1465                 1470             


Gly Glu  Asp Arg Phe Tyr Arg  Arg His Pro Glu Ala  Glu Met Asp 
    1475                 1480                 1485             


Arg Ala  His His His Gly Gly  His Gly Ser Thr Gln  Pro Glu Lys 
    1490                 1495                 1500             


Pro Ser  Leu Pro Gln Lys Gln  Ser Ser Leu Arg Ser  Arg Lys Leu 
    1505                 1510                 1515             


Pro Asp  Met Gly Cys Ser Leu  Pro Glu His Arg Ala  His Gln Glu 
    1520                 1525                 1530             


Ala Ser  His Arg Gln Phe Cys  Glu Ser Lys Asn Gly  Pro Pro Tyr 
    1535                 1540                 1545             


Pro Gln  Gly Ala Gly Gln Leu  Asp Tyr Gly Ser Lys  Gly Ile Pro 
    1550                 1555                 1560             


Asp Thr  Ser Glu Pro Val Ser  Tyr His Asn Ser Gly  Val Lys Tyr 
    1565                 1570                 1575             


Ala Ala  Ser Gly Gln Glu Ser  Leu Arg Leu Asn His  Lys Glu Val 
    1580                 1585                 1590             


Arg Leu  Ser Lys Glu Met Glu  Arg Pro Trp Val Arg  Gln Pro Ser 
    1595                 1600                 1605             


Ala Pro  Glu Lys His Ser Arg  Asp Cys Tyr Lys Glu  Glu Glu His 
    1610                 1615                 1620             


Leu Thr  Gln Ser Ile Val Pro  Pro Pro Lys Pro Glu  Arg Ser His 
    1625                 1630                 1635             


Ser Leu  Lys Leu His His Thr  Gln Asn Val Glu Arg  Asp Pro Ser 
    1640                 1645                 1650             


Val Leu  Tyr Gln Tyr Gln Pro  His Gly Lys Arg Gln  Ser Ser Val 
    1655                 1660                 1665             


Thr Val  Val Ser Gln Tyr Asp  Asn Leu Glu Asp Tyr  His Ser Leu 
    1670                 1675                 1680             


Pro Gln  His Gln Arg Gly Val  Phe Gly Gly Gly Gly  Met Gly Thr 
    1685                 1690                 1695             


Tyr Val  Pro Pro Gly Phe Pro  His Pro Gln Ser Arg  Thr Tyr Ala 
    1700                 1705                 1710             


Thr Ala  Leu Gly Gln Gly Ala  Phe Leu Pro Ala Glu  Leu Ser Leu 
    1715                 1720                 1725             


Gln His  Pro Glu Thr Gln Ile  His Ala Glu 
    1730                 1735             


<210>  1243
<211>  519
<212>  PRT
<213>  Human

<400>  1243

Met Asp Leu Val Gly Val Ala Ser Pro Glu Pro Gly Thr Ala Ala Ala 
1               5                   10                  15      


Trp Gly Pro Ser Lys Cys Pro Trp Ala Ile Pro Gln Asn Thr Ile Ser 
            20                  25                  30          


Cys Ser Leu Ala Asp Val Met Ser Glu Gln Leu Ala Lys Glu Leu Gln 
        35                  40                  45              


Leu Glu Glu Glu Ala Ala Val Phe Pro Glu Val Ala Val Ala Glu Gly 
    50                  55                  60                  


Pro Phe Ile Thr Gly Glu Asn Ile Asp Thr Ser Ser Asp Leu Met Leu 
65                  70                  75                  80  


Ala Gln Met Leu Gln Met Glu Tyr Asp Arg Glu Tyr Asp Ala Gln Leu 
                85                  90                  95      


Arg Arg Glu Glu Lys Lys Phe Asn Gly Asp Ser Lys Val Ser Ile Ser 
            100                 105                 110         


Phe Glu Asn Tyr Arg Lys Val His Pro Tyr Glu Asp Ser Asp Ser Ser 
        115                 120                 125             


Glu Asp Glu Val Asp Trp Gln Asp Thr Arg Asp Asp Pro Tyr Arg Pro 
    130                 135                 140                 


Ala Lys Pro Val Pro Thr Pro Lys Lys Gly Phe Ile Gly Lys Gly Lys 
145                 150                 155                 160 


Asp Ile Thr Thr Lys His Asp Glu Val Val Cys Gly Arg Lys Asn Thr 
                165                 170                 175     


Ala Arg Met Glu Asn Phe Ala Pro Glu Phe Gln Val Gly Asp Gly Ile 
            180                 185                 190         


Gly Met Asp Leu Lys Leu Ser Asn His Val Phe Asn Ala Leu Lys Gln 
        195                 200                 205             


His Ala Tyr Ser Glu Glu Arg Arg Ser Ala Arg Leu His Glu Lys Lys 
    210                 215                 220                 


Glu His Ser Thr Ala Glu Lys Ala Val Asp Pro Lys Thr Arg Leu Leu 
225                 230                 235                 240 


Met Tyr Lys Met Val Asn Ser Gly Met Leu Glu Thr Ile Thr Gly Cys 
                245                 250                 255     


Ile Ser Thr Gly Lys Glu Ser Val Val Phe His Ala Tyr Gly Gly Ser 
            260                 265                 270         


Met Glu Asp Glu Lys Glu Asp Ser Lys Val Ile Pro Thr Glu Cys Ala 
        275                 280                 285             


Ile Lys Val Phe Lys Thr Thr Leu Asn Glu Phe Lys Asn Arg Asp Lys 
    290                 295                 300                 


Tyr Ile Lys Asp Asp Phe Arg Phe Lys Asp Arg Phe Ser Lys Leu Asn 
305                 310                 315                 320 


Pro Arg Lys Ile Ile Arg Met Trp Ala Glu Lys Glu Met His Asn Leu 
                325                 330                 335     


Ala Arg Met Gln Arg Ala Gly Ile Pro Cys Pro Thr Val Val Leu Leu 
            340                 345                 350         


Lys Lys His Ile Leu Val Met Ser Phe Ile Gly His Asp Gln Val Pro 
        355                 360                 365             


Ala Pro Lys Leu Lys Glu Val Lys Leu Asn Ser Glu Glu Met Lys Glu 
    370                 375                 380                 


Ala Tyr Tyr Gln Thr Leu His Leu Met Arg Gln Leu Tyr His Glu Cys 
385                 390                 395                 400 


Thr Leu Val His Ala Asp Leu Ser Glu Tyr Asn Met Leu Trp His Ala 
                405                 410                 415     


Gly Lys Val Trp Leu Ile Asp Val Ser Gln Ser Val Glu Pro Thr His 
            420                 425                 430         


Pro His Gly Leu Glu Phe Leu Phe Arg Asp Cys Arg Asn Val Ser Gln 
        435                 440                 445             


Phe Phe Gln Lys Gly Gly Val Lys Glu Ala Leu Ser Glu Arg Glu Leu 
    450                 455                 460                 


Phe Asn Ala Val Ser Gly Leu Asn Ile Thr Ala Asp Asn Glu Ala Asp 
465                 470                 475                 480 


Phe Leu Ala Glu Ile Glu Ala Leu Glu Lys Met Asn Glu Asp His Val 
                485                 490                 495     


Gln Lys Asn Gly Arg Lys Ala Ala Ser Phe Leu Lys Asp Asp Gly Asp 
            500                 505                 510         


Pro Pro Leu Leu Tyr Asp Glu 
        515                 


<210>  1244
<211>  744
<212>  PRT
<213>  Human

<400>  1244

Met Gly Leu Gly Leu Leu Leu Pro Leu Leu Leu Leu Trp Thr Arg Gly 
1               5                   10                  15      


Thr Gln Gly Ser Glu Leu Asp Pro Lys Gly Gln His Val Cys Val Ala 
            20                  25                  30          


Ser Ser Pro Ser Ala Glu Leu Gln Cys Cys Ala Gly Trp Arg Gln Lys 
        35                  40                  45              


Asp Gln Glu Cys Thr Ile Pro Ile Cys Glu Gly Pro Asp Ala Cys Gln 
    50                  55                  60                  


Lys Asp Glu Val Cys Val Lys Pro Gly Leu Cys Arg Cys Lys Pro Gly 
65                  70                  75                  80  


Phe Phe Gly Ala His Cys Ser Ser Arg Cys Pro Gly Gln Tyr Trp Gly 
                85                  90                  95      


Pro Asp Cys Arg Glu Ser Cys Pro Cys His Pro His Gly Gln Cys Glu 
            100                 105                 110         


Pro Ala Thr Gly Ala Cys Gln Cys Gln Ala Asp Arg Trp Gly Ala Arg 
        115                 120                 125             


Cys Glu Phe Pro Cys Ala Cys Gly Pro His Gly Arg Cys Asp Pro Ala 
    130                 135                 140                 


Thr Gly Val Cys His Cys Glu Pro Gly Trp Trp Ser Ser Thr Cys Arg 
145                 150                 155                 160 


Arg Pro Cys Gln Cys Asn Thr Ala Ala Ala Arg Cys Glu Gln Ala Thr 
                165                 170                 175     


Gly Ala Cys Val Cys Lys Pro Gly Trp Trp Gly Arg Arg Cys Ser Phe 
            180                 185                 190         


Arg Cys Asn Cys His Gly Ser Pro Cys Glu Gln Asp Ser Gly Arg Cys 
        195                 200                 205             


Ala Cys Arg Pro Gly Trp Trp Gly Pro Glu Cys Gln Gln Gln Cys Glu 
    210                 215                 220                 


Cys Val Arg Gly Arg Cys Ser Ala Ala Ser Gly Glu Cys Thr Cys Pro 
225                 230                 235                 240 


Pro Gly Phe Arg Gly Ala Arg Cys Glu Leu Pro Cys Pro Ala Gly Ser 
                245                 250                 255     


His Gly Val Gln Cys Ala His Ser Cys Gly Arg Cys Lys His Asn Glu 
            260                 265                 270         


Pro Cys Ser Pro Asp Thr Gly Ser Cys Glu Ser Cys Glu Pro Gly Trp 
        275                 280                 285             


Asn Gly Thr Gln Cys Gln Gln Pro Cys Leu Pro Gly Thr Phe Gly Glu 
    290                 295                 300                 


Ser Cys Glu Gln Gln Cys Pro His Cys Arg His Gly Glu Ala Cys Glu 
305                 310                 315                 320 


Pro Asp Thr Gly His Cys Gln Arg Cys Ser Gly Ser Arg Asp Thr Ala 
                325                 330                 335     


Leu Ile Ala Gly Ser Leu Val Pro Leu Leu Leu Leu Phe Leu Gly Leu 
            340                 345                 350         


Ala Cys Cys Ala Cys Cys Cys Trp Ala Pro Arg Ser Asp Leu Lys Asp 
        355                 360                 365             


Arg Pro Ala Arg Asp Gly Ala Thr Val Ser Arg Met Lys Leu Gln Val 
    370                 375                 380                 


Trp Gly Thr Leu Thr Ser Leu Gly Ser Thr Leu Pro Cys Arg Ser Leu 
385                 390                 395                 400 


Ser Ser His Lys Leu Pro Trp Val Thr Val Ser His His Asp Pro Glu 
                405                 410                 415     


Val Pro Phe Asn His Ser Phe Ile Glu Pro Pro Ser Ala Gly Trp Ala 
            420                 425                 430         


Thr Asp Asp Ser Phe Ser Ser Asp Pro Glu Ser Gly Glu Ala Asp Glu 
        435                 440                 445             


Val Pro Ala Tyr Cys Val Pro Pro Gln Glu Gly Met Val Pro Val Ala 
    450                 455                 460                 


Gln Ala Gly Ser Ser Glu Ala Ser Leu Ala Ala Gly Ala Phe Pro Pro 
465                 470                 475                 480 


Pro Glu Asp Ala Ser Thr Pro Phe Ala Ile Pro Arg Thr Ser Ser Leu 
                485                 490                 495     


Ala Arg Ala Lys Arg Pro Ser Val Ser Phe Ala Glu Gly Thr Lys Phe 
            500                 505                 510         


Ala Pro Gln Ser Arg Arg Ser Ser Gly Glu Leu Ser Ser Pro Leu Arg 
        515                 520                 525             


Lys Pro Lys Arg Leu Ser Arg Gly Ala Gln Ser Gly Pro Glu Gly Arg 
    530                 535                 540                 


Glu Ala Glu Glu Ser Thr Gly Pro Glu Glu Ala Glu Ala Pro Glu Ser 
545                 550                 555                 560 


Phe Pro Ala Ala Ala Ser Pro Gly Asp Ser Ala Thr Gly His Arg Arg 
                565                 570                 575     


Pro Pro Leu Gly Gly Arg Thr Val Ala Glu His Val Glu Ala Ile Glu 
            580                 585                 590         


Gly Ser Val Gln Glu Ser Ser Gly Pro Val Thr Thr Ile Tyr Met Leu 
        595                 600                 605             


Ala Gly Lys Pro Arg Gly Ser Glu Gly Pro Val Arg Ser Val Phe Arg 
    610                 615                 620                 


His Phe Gly Ser Phe Gln Lys Gly Gln Ala Glu Ala Lys Val Lys Arg 
625                 630                 635                 640 


Ala Ile Pro Lys Pro Pro Arg Gln Ala Leu Asn Arg Lys Lys Gly Ser 
                645                 650                 655     


Pro Gly Leu Ala Ser Gly Ser Val Gly Gln Ser Pro Asn Ser Ala Pro 
            660                 665                 670         


Lys Ala Gly Leu Pro Gly Ala Thr Gly Pro Met Ala Val Arg Pro Glu 
        675                 680                 685             


Glu Ala Val Arg Gly Leu Gly Ala Gly Thr Glu Ser Ser Arg Arg Ala 
    690                 695                 700                 


Gln Glu Pro Val Ser Gly Cys Gly Ser Pro Glu Gln Asp Pro Gln Lys 
705                 710                 715                 720 


Gln Ala Glu Glu Glu Arg Gln Glu Glu Pro Glu Tyr Glu Asn Val Val 
                725                 730                 735     


Pro Ile Ser Arg Pro Pro Glu Pro 
            740                 


<210>  1245
<211>  1655
<212>  PRT
<213>  Human

<400>  1245

Met Leu Lys Cys Ile Pro Leu Trp Arg Cys Asn Arg His Val Glu Ser 
1               5                   10                  15      


Val Asp Lys Arg His Cys Ser Leu Gln Ala Val Pro Glu Glu Ile Tyr 
            20                  25                  30          


Arg Tyr Ser Arg Ser Leu Glu Glu Leu Leu Leu Asp Ala Asn Gln Leu 
        35                  40                  45              


Arg Glu Leu Pro Lys Pro Phe Phe Arg Leu Leu Asn Leu Arg Lys Leu 
    50                  55                  60                  


Gly Leu Ser Asp Asn Glu Ile Gln Arg Leu Pro Pro Glu Val Ala Asn 
65                  70                  75                  80  


Phe Met Gln Leu Val Glu Leu Asp Val Ser Arg Asn Asp Ile Pro Glu 
                85                  90                  95      


Ile Pro Glu Ser Ile Lys Phe Cys Lys Ala Leu Glu Ile Ala Asp Phe 
            100                 105                 110         


Ser Gly Asn Pro Leu Ser Arg Leu Pro Asp Gly Phe Thr Gln Leu Arg 
        115                 120                 125             


Ser Leu Ala His Leu Ala Leu Asn Asp Val Ser Leu Gln Ala Leu Pro 
    130                 135                 140                 


Gly Asp Val Gly Asn Leu Ala Asn Leu Val Thr Leu Glu Leu Arg Glu 
145                 150                 155                 160 


Asn Leu Leu Lys Ser Leu Pro Ala Ser Leu Ser Phe Leu Val Lys Leu 
                165                 170                 175     


Glu Gln Leu Asp Leu Gly Gly Asn Asp Leu Glu Val Leu Pro Asp Thr 
            180                 185                 190         


Leu Gly Ala Leu Pro Asn Leu Arg Glu Leu Trp Leu Asp Arg Asn Gln 
        195                 200                 205             


Leu Ser Ala Leu Pro Pro Glu Leu Gly Asn Leu Arg Arg Leu Val Cys 
    210                 215                 220                 


Leu Asp Val Ser Glu Asn Arg Leu Glu Glu Leu Pro Ala Glu Leu Gly 
225                 230                 235                 240 


Gly Leu Val Leu Leu Thr Asp Leu Leu Leu Ser Gln Asn Leu Leu Arg 
                245                 250                 255     


Arg Leu Pro Asp Gly Ile Gly Gln Leu Lys Gln Leu Ser Ile Leu Lys 
            260                 265                 270         


Val Asp Gln Asn Arg Leu Cys Glu Val Thr Glu Ala Ile Gly Asp Cys 
        275                 280                 285             


Glu Asn Leu Ser Glu Leu Ile Leu Thr Glu Asn Leu Leu Met Ala Leu 
    290                 295                 300                 


Pro Arg Ser Leu Gly Lys Leu Thr Lys Leu Thr Asn Leu Asn Val Asp 
305                 310                 315                 320 


Arg Asn His Leu Glu Ala Leu Pro Pro Glu Ile Gly Gly Cys Val Ala 
                325                 330                 335     


Leu Ser Val Leu Ser Leu Arg Asp Asn Arg Leu Ala Val Leu Pro Pro 
            340                 345                 350         


Glu Leu Ala His Thr Thr Glu Leu His Val Leu Asp Val Ala Gly Asn 
        355                 360                 365             


Arg Leu Gln Ser Leu Pro Phe Ala Leu Thr His Leu Asn Leu Lys Ala 
    370                 375                 380                 


Leu Trp Leu Ala Glu Asn Gln Ala Gln Pro Met Leu Arg Phe Gln Thr 
385                 390                 395                 400 


Glu Asp Asp Ala Arg Thr Gly Glu Lys Val Leu Thr Cys Tyr Leu Leu 
                405                 410                 415     


Pro Gln Gln Pro Pro Leu Ser Leu Glu Asp Ala Gly Gln Gln Gly Ser 
            420                 425                 430         


Leu Ser Glu Thr Trp Ser Asp Ala Pro Pro Ser Arg Val Ser Val Ile 
        435                 440                 445             


Gln Phe Leu Glu Ala Pro Ile Gly Asp Glu Asp Ala Glu Glu Ala Ala 
    450                 455                 460                 


Ala Glu Lys Arg Gly Leu Gln Arg Arg Ala Thr Pro His Pro Ser Glu 
465                 470                 475                 480 


Leu Lys Val Met Lys Arg Ser Ile Glu Gly Arg Arg Ser Glu Ala Cys 
                485                 490                 495     


Pro Cys Gln Pro Asp Ser Gly Ser Pro Leu Pro Ala Glu Glu Glu Lys 
            500                 505                 510         


Arg Leu Ser Ala Glu Ser Gly Leu Ser Glu Asp Ser Arg Pro Ser Ala 
        515                 520                 525             


Ser Thr Val Ser Glu Ala Glu Pro Glu Gly Pro Ser Ala Glu Ala Gln 
    530                 535                 540                 


Gly Gly Ser Gln Gln Glu Ala Thr Thr Ala Gly Gly Glu Glu Asp Ala 
545                 550                 555                 560 


Glu Glu Asp Tyr Gln Glu Pro Thr Val His Phe Ala Glu Asp Ala Leu 
                565                 570                 575     


Leu Pro Gly Asp Asp Arg Glu Ile Glu Glu Gly Gln Pro Glu Ala Pro 
            580                 585                 590         


Trp Thr Leu Pro Gly Gly Arg Gln Arg Leu Ile Arg Lys Asp Thr Pro 
        595                 600                 605             


His Tyr Lys Lys His Phe Lys Ile Ser Lys Leu Pro Gln Pro Glu Ala 
    610                 615                 620                 


Val Val Ala Leu Leu Gln Gly Met Gln Pro Asp Gly Glu Gly Pro Val 
625                 630                 635                 640 


Ala Pro Gly Gly Trp His Asn Gly Pro His Ala Pro Trp Ala Pro Arg 
                645                 650                 655     


Ala Gln Lys Glu Glu Glu Glu Glu Glu Glu Gly Ser Pro Gln Glu Glu 
            660                 665                 670         


Glu Glu Glu Glu Glu Glu Glu Asn Arg Ala Glu Glu Glu Glu Ala Ser 
        675                 680                 685             


Thr Glu Glu Glu Asp Lys Glu Gly Ala Val Val Ser Ala Pro Ser Val 
    690                 695                 700                 


Lys Gly Val Ser Phe Asp Gln Ala Asn Asn Leu Leu Ile Glu Pro Ala 
705                 710                 715                 720 


Arg Ile Glu Glu Glu Glu Leu Thr Leu Thr Ile Leu Arg Gln Thr Gly 
                725                 730                 735     


Gly Leu Gly Ile Ser Ile Ala Gly Gly Lys Gly Ser Thr Pro Tyr Lys 
            740                 745                 750         


Gly Asp Asp Glu Gly Ile Phe Ile Ser Arg Val Ser Glu Glu Gly Pro 
        755                 760                 765             


Ala Ala Arg Ala Gly Val Arg Val Gly Asp Lys Leu Leu Glu Val Asn 
    770                 775                 780                 


Gly Val Ala Leu Gln Gly Ala Glu His His Glu Ala Val Glu Ala Leu 
785                 790                 795                 800 


Arg Gly Ala Gly Thr Ala Val Gln Met Arg Val Trp Arg Glu Arg Met 
                805                 810                 815     


Val Glu Pro Glu Asn Ala Val Thr Ile Thr Pro Leu Arg Pro Glu Asp 
            820                 825                 830         


Asp Tyr Ser Pro Arg Glu Arg Arg Gly Gly Gly Leu Arg Leu Pro Leu 
        835                 840                 845             


Leu Pro Pro Glu Ser Pro Gly Pro Leu Arg Gln Arg His Val Ala Cys 
    850                 855                 860                 


Leu Ala Arg Ser Glu Arg Gly Leu Gly Phe Ser Ile Ala Gly Gly Lys 
865                 870                 875                 880 


Gly Ser Thr Pro Tyr Arg Ala Gly Asp Ala Gly Ile Phe Val Ser Arg 
                885                 890                 895     


Ile Ala Glu Gly Gly Ala Ala His Arg Ala Gly Thr Leu Gln Val Gly 
            900                 905                 910         


Asp Arg Val Leu Ser Ile Asn Gly Val Asp Val Thr Glu Ala Arg His 
        915                 920                 925             


Asp His Ala Val Ser Leu Leu Thr Ala Ala Ser Pro Thr Ile Ala Leu 
    930                 935                 940                 


Leu Leu Glu Arg Glu Ala Gly Gly Pro Leu Pro Pro Ser Pro Leu Pro 
945                 950                 955                 960 


His Ser Ser Pro Pro Thr Ala Ala Val Ala Thr Thr Ser Ile Thr Thr 
                965                 970                 975     


Ala Thr Pro Gly Val Pro Gly Leu Pro Ser Leu Ala Pro Ser Leu Leu 
            980                 985                 990         


Ala Ala Ala Leu Glu Gly Pro Tyr  Pro Val Glu Glu Ile  Arg Leu Pro 
        995                 1000                 1005             


Arg Ala  Gly Gly Pro Leu Gly  Leu Ser Ile Val Gly  Gly Ser Asp 
    1010                 1015                 1020             


His Ser  Ser His Pro Phe Gly  Val Gln Glu Pro Gly  Val Phe Ile 
    1025                 1030                 1035             


Ser Lys  Val Leu Pro Arg Gly  Leu Ala Ala Arg Ser  Gly Leu Arg 
    1040                 1045                 1050             


Val Gly  Asp Arg Ile Leu Ala  Val Asn Gly Gln Asp  Val Arg Asp 
    1055                 1060                 1065             


Ala Thr  His Gln Glu Ala Val  Ser Ala Leu Leu Arg  Pro Cys Leu 
    1070                 1075                 1080             


Glu Leu  Ser Leu Leu Val Arg  Arg Asp Pro Ala Pro  Pro Gly Leu 
    1085                 1090                 1095             


Arg Glu  Leu Cys Ile Gln Lys  Ala Pro Gly Glu Arg  Leu Gly Ile 
    1100                 1105                 1110             


Ser Ile  Arg Gly Gly Ala Arg  Gly His Ala Gly Asn  Pro Arg Asp 
    1115                 1120                 1125             


Pro Thr  Asp Glu Gly Ile Phe  Ile Ser Lys Val Ser  Pro Thr Gly 
    1130                 1135                 1140             


Ala Ala  Gly Arg Asp Gly Arg  Leu Arg Val Gly Leu  Arg Leu Leu 
    1145                 1150                 1155             


Glu Val  Asn Gln Gln Ser Leu  Leu Gly Leu Thr His  Gly Glu Ala 
    1160                 1165                 1170             


Val Gln  Leu Leu Arg Ser Val  Gly Asp Thr Leu Thr  Val Leu Val 
    1175                 1180                 1185             


Cys Asp  Gly Phe Glu Ala Ser  Thr Asp Ala Ala Leu  Glu Val Ser 
    1190                 1195                 1200             


Pro Gly  Val Ile Ala Asn Pro  Phe Ala Ala Gly Ile  Gly His Arg 
    1205                 1210                 1215             


Asn Ser  Leu Glu Ser Ile Ser  Ser Ile Asp Arg Glu  Leu Ser Pro 
    1220                 1225                 1230             


Glu Gly  Pro Gly Lys Glu Lys  Glu Leu Pro Gly Gln  Thr Leu His 
    1235                 1240                 1245             


Trp Gly  Pro Glu Ala Thr Glu  Ala Ala Gly Arg Gly  Leu Gln Pro 
    1250                 1255                 1260             


Leu Lys  Leu Asp Tyr Arg Ala  Leu Ala Ala Val Pro  Ser Ala Gly 
    1265                 1270                 1275             


Ser Val  Gln Arg Val Pro Ser  Gly Ala Ala Gly Gly  Lys Met Ala 
    1280                 1285                 1290             


Glu Ser  Pro Cys Ser Pro Ser  Gly Gln Gln Pro Pro  Ser Pro Pro 
    1295                 1300                 1305             


Ser Pro  Asp Glu Leu Pro Ala  Asn Val Lys Gln Ala  Tyr Arg Ala 
    1310                 1315                 1320             


Phe Ala  Ala Val Pro Thr Ser  His Pro Pro Glu Asp  Ala Pro Ala 
    1325                 1330                 1335             


Gln Pro  Pro Thr Pro Gly Pro  Ala Ala Ser Pro Glu  Gln Leu Ser 
    1340                 1345                 1350             


Phe Arg  Glu Arg Gln Lys Tyr  Phe Glu Leu Glu Val  Arg Val Pro 
    1355                 1360                 1365             


Gln Ala  Glu Gly Pro Pro Lys  Arg Val Ser Leu Val  Gly Ala Asp 
    1370                 1375                 1380             


Asp Leu  Arg Lys Met Gln Glu  Glu Glu Ala Arg Lys  Leu Gln Gln 
    1385                 1390                 1395             


Lys Arg  Ala Gln Met Leu Arg  Glu Ala Ala Glu Ala  Gly Ala Glu 
    1400                 1405                 1410             


Ala Arg  Leu Ala Leu Asp Gly  Glu Thr Leu Gly Glu  Glu Glu Gln 
    1415                 1420                 1425             


Glu Asp  Glu Gln Pro Pro Trp  Ala Ser Pro Ser Pro  Thr Ser Arg 
    1430                 1435                 1440             


Gln Ser  Pro Ala Ser Pro Pro  Pro Leu Gly Gly Gly  Ala Pro Val 
    1445                 1450                 1455             


Arg Thr  Ala Lys Ala Glu Arg  Arg His Gln Glu Arg  Leu Arg Val 
    1460                 1465                 1470             


Gln Ser  Pro Glu Pro Pro Ala  Pro Glu Arg Ala Leu  Ser Pro Ala 
    1475                 1480                 1485             


Glu Leu  Arg Ala Leu Glu Ala  Glu Lys Arg Ala Leu  Trp Arg Ala 
    1490                 1495                 1500             


Ala Arg  Met Lys Ser Leu Glu  Gln Asp Ala Leu Arg  Ala Gln Met 
    1505                 1510                 1515             


Val Leu  Ser Arg Ser Gln Glu  Gly Arg Gly Thr Arg  Gly Pro Leu 
    1520                 1525                 1530             


Glu Arg  Leu Ala Glu Ala Pro  Ser Pro Ala Pro Thr  Pro Ser Pro 
    1535                 1540                 1545             


Thr Pro  Val Glu Asp Leu Gly  Pro Gln Thr Ser Thr  Ser Pro Gly 
    1550                 1555                 1560             


Arg Leu  Pro Leu Ser Gly Lys  Lys Phe Asp Tyr Arg  Ala Phe Ala 
    1565                 1570                 1575             


Ala Leu  Pro Ser Ser Arg Pro  Val Tyr Asp Ile Gln  Ser Pro Asp 
    1580                 1585                 1590             


Phe Ala  Glu Glu Leu Arg Ser  Leu Glu Pro Ser Pro  Ser Pro Gly 
    1595                 1600                 1605             


Pro Gln  Glu Glu Asp Gly Glu  Val Ala Leu Val Leu  Leu Gly Arg 
    1610                 1615                 1620             


Pro Ser  Pro Gly Ala Val Gly  Pro Glu Asp Val Ala  Leu Cys Ser 
    1625                 1630                 1635             


Ser Arg  Arg Pro Val Arg Pro  Gly Arg Arg Gly Leu  Gly Pro Val 
    1640                 1645                 1650             


Pro Ser  
    1655 


<210>  1246
<211>  115
<212>  PRT
<213>  Human

<400>  1246

Met Ser Arg His Ser Arg Leu Gln Arg Gln Val Leu Ser Leu Tyr Arg 
1               5                   10                  15      


Asp Leu Leu Arg Ala Gly Arg Gly Lys Pro Gly Ala Glu Ala Arg Val 
            20                  25                  30          


Arg Ala Glu Phe Arg Gln His Ala Gly Leu Pro Arg Ser Asp Val Leu 
        35                  40                  45              


Arg Ile Glu Tyr Leu Tyr Arg Arg Gly Arg Arg Gln Leu Gln Leu Leu 
    50                  55                  60                  


Arg Ser Gly His Ala Thr Ala Met Gly Ala Phe Val Arg Pro Arg Ala 
65                  70                  75                  80  


Pro Thr Gly Glu Pro Gly Gly Val Gly Ser Gln Pro Asp Asp Gly Asp 
                85                  90                  95      


Ser Pro Arg Asn Pro His Asp Ser Thr Gly Ala Pro Glu Thr Arg Pro 
            100                 105                 110         


Asp Gly Arg 
        115 


<210>  1247
<211>  645
<212>  PRT
<213>  Human

<400>  1247

Met Ser Leu Lys Met Asp Asn Arg Asp Val Ala Gly Lys Ala Asn Arg 
1               5                   10                  15      


Trp Phe Gly Val Ala Pro Pro Lys Ser Gly Lys Met Asn Met Asn Ile 
            20                  25                  30          


Leu His Gln Glu Glu Leu Ile Ala Gln Lys Lys Arg Glu Ile Glu Ala 
        35                  40                  45              


Lys Met Glu Gln Lys Ala Lys Gln Asn Gln Val Ala Ser Pro Gln Pro 
    50                  55                  60                  


Pro His Pro Gly Glu Ile Thr Asn Ala His Asn Ser Ser Cys Ile Ser 
65                  70                  75                  80  


Asn Lys Phe Ala Asn Asp Gly Ser Phe Leu Gln Gln Phe Leu Lys Leu 
                85                  90                  95      


Gln Lys Ala Gln Thr Ser Thr Asp Ala Pro Thr Ser Ala Pro Ser Ala 
            100                 105                 110         


Pro Pro Ser Thr Pro Thr Pro Ser Ala Gly Lys Arg Ser Leu Leu Ile 
        115                 120                 125             


Ser Arg Arg Thr Gly Leu Gly Leu Ala Ser Leu Pro Gly Pro Val Lys 
    130                 135                 140                 


Ser Tyr Ser His Ala Lys Gln Leu Pro Val Ala His Arg Pro Ser Val 
145                 150                 155                 160 


Phe Gln Ser Pro Asp Glu Asp Glu Glu Glu Asp Tyr Glu Gln Trp Leu 
                165                 170                 175     


Glu Ile Lys Val Ser Pro Pro Glu Gly Ala Glu Thr Arg Lys Val Ile 
            180                 185                 190         


Glu Lys Leu Ala Arg Phe Val Ala Glu Gly Gly Pro Glu Leu Glu Lys 
        195                 200                 205             


Val Ala Met Glu Asp Tyr Lys Asp Asn Pro Ala Phe Ala Phe Leu His 
    210                 215                 220                 


Asp Lys Asn Ser Arg Glu Phe Leu Tyr Tyr Arg Lys Lys Val Ala Glu 
225                 230                 235                 240 


Ile Arg Lys Glu Ala Gln Lys Ser Gln Ala Ala Ser Gln Lys Val Ser 
                245                 250                 255     


Pro Pro Glu Asp Glu Glu Val Lys Asn Leu Ala Glu Lys Leu Ala Arg 
            260                 265                 270         


Phe Ile Ala Asp Gly Gly Pro Glu Val Glu Thr Ile Ala Leu Gln Asn 
        275                 280                 285             


Asn Arg Glu Asn Gln Ala Phe Ser Phe Leu Tyr Glu Pro Asn Ser Gln 
    290                 295                 300                 


Gly Tyr Lys Tyr Tyr Arg Gln Lys Leu Glu Glu Phe Arg Lys Ala Lys 
305                 310                 315                 320 


Ala Ser Ser Thr Gly Ser Phe Thr Ala Pro Asp Pro Gly Leu Lys Arg 
                325                 330                 335     


Lys Ser Pro Pro Glu Ala Leu Ser Gly Ser Leu Pro Pro Ala Thr Thr 
            340                 345                 350         


Cys Pro Ala Ser Ser Thr Pro Ala Pro Thr Ile Ile Pro Ala Pro Ala 
        355                 360                 365             


Ala Pro Gly Lys Pro Ala Ser Ala Ala Thr Val Lys Arg Lys Arg Lys 
    370                 375                 380                 


Ser Arg Trp Gly Pro Glu Glu Asp Lys Val Glu Leu Pro Pro Ala Glu 
385                 390                 395                 400 


Leu Val Gln Arg Asp Val Asp Ala Ser Pro Ser Pro Leu Ser Val Gln 
                405                 410                 415     


Asp Leu Lys Gly Leu Gly Tyr Glu Lys Gly Lys Pro Val Gly Leu Val 
            420                 425                 430         


Gly Val Thr Glu Leu Ser Asp Ala Gln Lys Lys Gln Leu Lys Glu Gln 
        435                 440                 445             


Gln Glu Met Gln Gln Met Tyr Asp Met Ile Met Gln His Lys Arg Ala 
    450                 455                 460                 


Met Gln Asp Met Gln Leu Leu Trp Glu Lys Ala Val Gln Gln His Gln 
465                 470                 475                 480 


His Gly Tyr Asp Ser Asp Glu Glu Val Asp Ser Glu Leu Gly Thr Trp 
                485                 490                 495     


Glu His Gln Leu Arg Arg Met Glu Met Asp Lys Thr Arg Glu Trp Ala 
            500                 505                 510         


Glu Gln Leu Thr Lys Met Gly Arg Gly Lys His Phe Ile Gly Asp Phe 
        515                 520                 525             


Leu Pro Pro Asp Glu Leu Glu Lys Phe Met Glu Thr Phe Lys Ala Leu 
    530                 535                 540                 


Lys Glu Gly Arg Glu Pro Asp Tyr Ser Glu Tyr Lys Glu Phe Lys Leu 
545                 550                 555                 560 


Thr Val Glu Asn Ile Gly Tyr Gln Met Leu Met Lys Met Gly Trp Lys 
                565                 570                 575     


Glu Gly Glu Gly Leu Gly Ser Glu Gly Gln Gly Ile Lys Asn Pro Val 
            580                 585                 590         


Asn Lys Gly Thr Thr Thr Val Asp Gly Ala Gly Phe Gly Ile Asp Arg 
        595                 600                 605             


Pro Ala Glu Leu Ser Lys Glu Asp Asp Glu Tyr Glu Ala Phe Arg Lys 
    610                 615                 620                 


Arg Met Met Leu Ala Tyr Arg Phe Arg Pro Asn Pro Leu Asn Asn Pro 
625                 630                 635                 640 


Arg Arg Pro Tyr Tyr 
                645 


<210>  1248
<211>  1211
<212>  PRT
<213>  Human

<400>  1248

Met Lys Asn Leu Leu Thr Glu Lys Cys Ile Ser Ser His Asn Phe His 
1               5                   10                  15      


Gln Lys Val Ile Lys Gln Arg Met Glu Lys Lys Val Asp Ser Arg Tyr 
            20                  25                  30          


Phe Lys Asp Gly Ala Val Lys Lys Pro Tyr Ser Ala Lys Thr Leu Ser 
        35                  40                  45              


Asn Lys Lys Ser Ser Ala Ser Phe Gly Ile Arg Arg Glu Leu Pro Ser 
    50                  55                  60                  


Thr Ser His Leu Val Gln Tyr Arg Gly Thr His Thr Cys Thr Arg Gln 
65                  70                  75                  80  


Gly Arg Leu Arg Glu Leu Arg Ile Arg Cys Val Ala Arg Lys Phe Leu 
                85                  90                  95      


Tyr Leu Trp Ile Arg Met Thr Phe Gly Arg Val Phe Pro Ser Lys Ala 
            100                 105                 110         


Arg Phe Tyr Tyr Glu Gln Arg Leu Leu Arg Lys Val Phe Glu Glu Trp 
        115                 120                 125             


Lys Glu Glu Trp Trp Val Phe Gln His Glu Trp Lys Leu Cys Val Arg 
    130                 135                 140                 


Ala Asp Cys His Tyr Arg Tyr Tyr Leu Tyr Asn Leu Met Phe Gln Thr 
145                 150                 155                 160 


Trp Lys Thr Tyr Val Arg Gln Gln Gln Glu Met Arg Asn Lys Tyr Ile 
                165                 170                 175     


Arg Ala Glu Val His Asp Ala Lys Gln Lys Met Arg Gln Ala Trp Lys 
            180                 185                 190         


Ser Trp Leu Ile Tyr Val Val Val Arg Arg Thr Lys Leu Gln Met Gln 
        195                 200                 205             


Thr Thr Ala Leu Glu Phe Arg Gln Arg Ile Ile Leu Arg Val Trp Trp 
    210                 215                 220                 


Ser Thr Trp Arg Gln Arg Leu Gly Gln Val Arg Val Ser Arg Ala Leu 
225                 230                 235                 240 


His Ala Ser Ala Leu Lys His Arg Ala Leu Ser Leu Gln Val Gln Ala 
                245                 250                 255     


Trp Ser Gln Trp Arg Glu Gln Leu Leu Tyr Val Gln Lys Glu Lys Gln 
            260                 265                 270         


Lys Val Val Ser Ala Val Lys His His Gln His Trp Gln Lys Arg Arg 
        275                 280                 285             


Phe Leu Lys Ala Trp Leu Glu Tyr Leu Gln Val Arg Arg Val Lys Arg 
    290                 295                 300                 


Gln Gln Asn Glu Met Ala Glu Arg Phe His His Val Thr Val Leu Gln 
305                 310                 315                 320 


Ile Tyr Phe Cys Asp Trp Gln Gln Ala Trp Glu Arg Arg Glu Ser Leu 
                325                 330                 335     


Tyr Ala His His Ala Gln Val Glu Lys Leu Ala Arg Lys Met Ala Leu 
            340                 345                 350         


Arg Arg Ala Phe Thr His Trp Lys His Tyr Met Leu Leu Cys Ala Glu 
        355                 360                 365             


Glu Ala Ala Gln Phe Glu Met Ala Glu Glu His His Arg His Ser Gln 
    370                 375                 380                 


Leu Leu Leu His Arg Phe Trp Asn Leu Trp Arg Ser Gln Ile Glu Gln 
385                 390                 395                 400 


Lys Lys Glu Arg Glu Leu Leu Pro Leu Leu His Ala Ala Trp Asp His 
                405                 410                 415     


Tyr Arg Ile Ala Leu Leu Cys Lys Cys Ile Glu Leu Trp Leu Gln Tyr 
            420                 425                 430         


Thr Gln Lys Arg Arg Tyr Lys Gln Leu Leu Gln Ala Arg Ala Asp Gly 
        435                 440                 445             


His Phe Gln Gln Arg Ala Leu Pro Ala Ala Phe His Thr Trp Asn Arg 
    450                 455                 460                 


Leu Trp Arg Trp Arg His Gln Glu Asn Val Leu Ser Ala Arg Ala Thr 
465                 470                 475                 480 


Arg Phe His Arg Glu Thr Leu Glu Lys Gln Val Phe Ser Leu Trp Arg 
                485                 490                 495     


Gln Lys Met Phe Gln His Arg Glu Asn Arg Leu Ala Glu Arg Met Ala 
            500                 505                 510         


Ile Leu His Ala Glu Arg Gln Leu Leu Tyr Arg Ser Trp Phe Met Trp 
        515                 520                 525             


His Gln Gln Ala Ala Ala Arg His Gln Glu Gln Glu Trp Gln Thr Val 
    530                 535                 540                 


Ala Cys Ala His His Arg His Gly Arg Leu Lys Lys Ala Phe Cys Leu 
545                 550                 555                 560 


Trp Arg Glu Ser Ala Gln Gly Leu Arg Thr Glu Arg Thr Gly Arg Val 
                565                 570                 575     


Arg Ala Ala Glu Phe His Met Ala Gln Leu Leu Arg Trp Ala Trp Ser 
            580                 585                 590         


Gln Trp Arg Glu Cys Leu Ala Leu Arg Gly Ala Glu Arg Gln Lys Leu 
        595                 600                 605             


Met Arg Ala Asp Leu His His Gln His Ser Val Leu His Arg Ala Leu 
    610                 615                 620                 


Gln Ala Trp Val Thr Tyr Gln Gly Arg Val Arg Ser Ile Leu Arg Glu 
625                 630                 635                 640 


Val Ala Ala Arg Glu Ser Gln His Asn Arg Gln Leu Leu Arg Gly Ala 
                645                 650                 655     


Leu Arg Arg Trp Lys Glu Asn Thr Met Ala Arg Val Asp Glu Ala Lys 
            660                 665                 670         


Lys Thr Phe Gln Ala Ser Thr His Tyr Arg Arg Thr Ile Cys Ser Lys 
        675                 680                 685             


Val Leu Val Gln Trp Arg Glu Ala Val Ser Val Gln Met Tyr Tyr Arg 
    690                 695                 700                 


Gln Gln Glu Asp Cys Ala Ile Trp Glu Ala Gln Lys Val Leu Asp Arg 
705                 710                 715                 720 


Gly Cys Leu Arg Thr Trp Phe Gln Arg Trp Trp Asp Cys Ser Arg Arg 
                725                 730                 735     


Ser Ala Gln Gln Arg Leu Gln Leu Glu Arg Ala Val Gln His His His 
            740                 745                 750         


Arg Gln Leu Leu Leu Glu Gly Leu Ala Arg Trp Lys Thr His His Leu 
        755                 760                 765             


Gln Cys Val Arg Lys Arg Leu Leu His Arg Gln Ser Thr Gln Leu Leu 
    770                 775                 780                 


Ala Gln Arg Leu Ser Arg Thr Cys Phe Arg Gln Trp Arg Gln Gln Leu 
785                 790                 795                 800 


Ala Ala Arg Arg Gln Glu Gln Arg Ala Thr Val Arg Ala Leu Trp Phe 
                805                 810                 815     


Trp Ala Phe Ser Leu Gln Ala Lys Val Trp Ala Thr Trp Leu Ala Phe 
            820                 825                 830         


Val Leu Glu Arg Arg Arg Lys Lys Ala Arg Leu Gln Trp Ala Leu Gln 
        835                 840                 845             


Ala Tyr Gln Gly Gln Leu Leu Gln Glu Gly Ala Thr Arg Leu Leu Arg 
    850                 855                 860                 


Phe Ala Ala Ser Met Lys Ala Ser Arg Gln Gln Leu Gln Ala Gln Gln 
865                 870                 875                 880 


Gln Val Gln Ala Ala His Ser Leu His Arg Ala Val Arg Arg Cys Ala 
                885                 890                 895     


Thr Leu Trp Lys Gln Lys Val Leu Gly Arg Gly Gly Lys Pro Gln Pro 
            900                 905                 910         


Leu Ala Ala Ile Ala Pro Ser Arg Lys Val Thr Phe Glu Gly Pro Leu 
        915                 920                 925             


Leu Asn Arg Ile Ala Ala Gly Ala Gly Asp Gly Thr Leu Glu Thr Lys 
    930                 935                 940                 


Arg Pro Gln Ala Ser Arg Pro Leu Gly Ala Leu Gly Arg Leu Ala Ala 
945                 950                 955                 960 


Glu Glu Pro His Ala Leu Glu Leu Asn Thr Ala His Ser Ala Arg Lys 
                965                 970                 975     


Gln Pro Arg Arg Pro His Phe Leu Leu Glu Pro Ala Gln Ser Gln Arg 
            980                 985                 990         


Pro Gln Lys Pro Gln Glu His Gly  Leu Gly Met Ala Gln  Pro Ala Ala 
        995                 1000                 1005             


Pro Ser  Leu Thr Arg Pro Phe  Leu Ala Glu Ala Pro  Thr Ala Leu 
    1010                 1015                 1020             


Val Pro  His Ser Pro Leu Pro  Gly Ala Leu Ser Ser  Ala Pro Gly 
    1025                 1030                 1035             


Pro Lys  Gln Pro Pro Thr Ala  Ser Thr Gly Pro Glu  Leu Leu Leu 
    1040                 1045                 1050             


Leu Pro  Leu Ser Ser Phe Met  Pro Cys Gly Ala Ala  Ala Pro Ala 
    1055                 1060                 1065             


Arg Val  Ser Ala Gln Arg Ala  Thr Pro Arg Asp Lys  Pro Pro Val 
    1070                 1075                 1080             


Pro Ser  Ser Leu Ala Ser Val  Pro Asp Pro His Leu  Leu Leu Pro 
    1085                 1090                 1095             


Gly Asp  Phe Ser Ala Thr Arg  Ala Gly Pro Gly Leu  Ser Thr Ala 
    1100                 1105                 1110             


Gly Ser  Leu Asp Leu Glu Ala  Glu Leu Glu Glu Ile  Gln Gln Gln 
    1115                 1120                 1125             


Leu Leu  His Tyr Gln Thr Thr  Lys Gln Asn Leu Trp  Ser Cys Arg 
    1130                 1135                 1140             


Arg Gln  Ala Ser Ser Leu Arg  Arg Trp Leu Glu Leu  Asn Arg Glu 
    1145                 1150                 1155             


Glu Pro  Gly Pro Glu Asp Gln  Glu Val Glu Gln Gln  Val Gln Lys 
    1160                 1165                 1170             


Glu Leu  Glu Gln Val Glu Met  Gln Ile Gln Leu Leu  Ala Glu Glu 
    1175                 1180                 1185             


Leu Gln  Ala Gln Arg Gln Pro  Ile Gly Ala Cys Val  Ala Arg Ile 
    1190                 1195                 1200             


Gln Ala  Leu Arg Gln Ala Leu  Cys 
    1205                 1210     


<210>  1249
<211>  707
<212>  PRT
<213>  Human

<400>  1249

Met Ser Arg Asp Arg Phe Arg Ser Arg Gly Gly Gly Gly Gly Gly Phe 
1               5                   10                  15      


His Arg Arg Gly Gly Gly Gly Gly Arg Gly Gly Leu His Asp Phe Arg 
            20                  25                  30          


Ser Pro Pro Pro Gly Met Gly Leu Asn Gln Asn Arg Gly Pro Met Gly 
        35                  40                  45              


Pro Gly Pro Gly Gln Ser Gly Pro Lys Pro Pro Ile Pro Pro Pro Pro 
    50                  55                  60                  


Pro His Gln Gln Gln Gln Gln Pro Pro Pro Gln Gln Pro Pro Pro Gln 
65                  70                  75                  80  


Gln Pro Pro Pro His Gln Pro Pro Pro His Pro Gln Pro His Gln Gln 
                85                  90                  95      


Gln Gln Pro Pro Pro Pro Pro Gln Asp Ser Ser Lys Pro Val Val Ala 
            100                 105                 110         


Gln Gly Pro Gly Pro Ala Pro Gly Val Gly Ser Ala Pro Pro Ala Ser 
        115                 120                 125             


Ser Ser Ala Pro Pro Ala Thr Pro Pro Thr Ser Gly Ala Pro Pro Gly 
    130                 135                 140                 


Ser Gly Pro Gly Pro Thr Pro Thr Pro Pro Pro Ala Val Thr Ser Ala 
145                 150                 155                 160 


Pro Pro Gly Ala Pro Pro Pro Thr Pro Pro Ser Ser Gly Val Pro Thr 
                165                 170                 175     


Thr Pro Pro Gln Ala Gly Gly Pro Pro Pro Pro Pro Ala Ala Val Pro 
            180                 185                 190         


Gly Pro Gly Pro Gly Pro Lys Gln Gly Pro Gly Pro Gly Gly Pro Lys 
        195                 200                 205             


Gly Gly Lys Met Pro Gly Gly Pro Lys Pro Gly Gly Gly Pro Gly Leu 
    210                 215                 220                 


Ser Thr Pro Gly Gly His Pro Lys Pro Pro His Arg Gly Gly Gly Glu 
225                 230                 235                 240 


Pro Arg Gly Gly Arg Gln His His Pro Pro Tyr His Gln Gln His His 
                245                 250                 255     


Gln Gly Pro Pro Pro Gly Gly Pro Gly Gly Arg Ser Glu Glu Lys Ile 
            260                 265                 270         


Ser Asp Ser Glu Gly Phe Lys Ala Asn Leu Ser Leu Leu Arg Arg Pro 
        275                 280                 285             


Gly Glu Lys Thr Tyr Thr Gln Arg Cys Arg Leu Phe Val Gly Asn Leu 
    290                 295                 300                 


Pro Ala Asp Ile Thr Glu Asp Glu Phe Lys Arg Leu Phe Ala Lys Tyr 
305                 310                 315                 320 


Gly Glu Pro Gly Glu Val Phe Ile Asn Lys Gly Lys Gly Phe Gly Phe 
                325                 330                 335     


Ile Lys Leu Glu Ser Arg Ala Leu Ala Glu Ile Ala Lys Ala Glu Leu 
            340                 345                 350         


Asp Asp Thr Pro Met Arg Gly Arg Gln Leu Arg Val Arg Phe Ala Thr 
        355                 360                 365             


His Ala Ala Ala Leu Ser Val Arg Asn Leu Ser Pro Tyr Val Ser Asn 
    370                 375                 380                 


Glu Leu Leu Glu Glu Ala Phe Ser Gln Phe Gly Pro Ile Glu Arg Ala 
385                 390                 395                 400 


Val Val Ile Val Asp Asp Arg Gly Arg Ser Thr Gly Lys Gly Ile Val 
                405                 410                 415     


Glu Phe Ala Ser Lys Pro Ala Ala Arg Lys Ala Phe Glu Arg Cys Ser 
            420                 425                 430         


Glu Gly Val Phe Leu Leu Thr Thr Thr Pro Arg Pro Val Ile Val Glu 
        435                 440                 445             


Pro Leu Glu Gln Leu Asp Asp Glu Asp Gly Leu Pro Glu Lys Leu Ala 
    450                 455                 460                 


Gln Lys Asn Pro Met Tyr Gln Lys Glu Arg Glu Thr Pro Pro Arg Phe 
465                 470                 475                 480 


Ala Gln His Gly Thr Phe Glu Tyr Glu Tyr Ser Gln Arg Trp Lys Ser 
                485                 490                 495     


Leu Asp Glu Met Glu Lys Gln Gln Arg Glu Gln Val Glu Lys Asn Met 
            500                 505                 510         


Lys Asp Ala Lys Asp Lys Leu Glu Ser Glu Met Glu Asp Ala Tyr His 
        515                 520                 525             


Glu His Gln Ala Asn Leu Leu Arg Gln Asp Leu Met Arg Arg Gln Glu 
    530                 535                 540                 


Glu Leu Arg Arg Met Glu Glu Leu His Asn Gln Glu Met Gln Lys Arg 
545                 550                 555                 560 


Lys Glu Met Gln Leu Arg Gln Glu Glu Glu Arg Arg Arg Arg Glu Glu 
                565                 570                 575     


Glu Met Met Ile Arg Gln Arg Glu Met Glu Glu Gln Met Arg Arg Gln 
            580                 585                 590         


Arg Glu Glu Ser Tyr Ser Arg Met Gly Tyr Met Asp Pro Arg Glu Arg 
        595                 600                 605             


Asp Met Arg Met Gly Gly Gly Gly Ala Met Asn Met Gly Asp Pro Tyr 
    610                 615                 620                 


Gly Ser Gly Gly Gln Lys Phe Pro Pro Leu Gly Gly Gly Gly Gly Ile 
625                 630                 635                 640 


Gly Tyr Glu Ala Asn Pro Gly Val Pro Pro Ala Thr Met Ser Gly Ser 
                645                 650                 655     


Met Met Gly Ser Asp Met Arg Thr Glu Arg Phe Gly Gln Gly Gly Ala 
            660                 665                 670         


Gly Pro Val Gly Gly Gln Gly Pro Arg Gly Met Gly Pro Gly Thr Pro 
        675                 680                 685             


Ala Gly Tyr Gly Arg Gly Arg Glu Glu Tyr Glu Gly Pro Asn Lys Lys 
    690                 695                 700                 


Pro Arg Phe 
705         


<210>  1250
<211>  93
<212>  PRT
<213>  Human

<400>  1250

Met Ser Gly Leu Arg Val Tyr Ser Thr Ser Val Thr Gly Ser Arg Glu 
1               5                   10                  15      


Ile Lys Ser Gln Gln Ser Glu Val Thr Arg Ile Leu Asp Gly Lys Arg 
            20                  25                  30          


Ile Gln Tyr Gln Leu Val Asp Ile Ser Gln Asp Asn Ala Leu Arg Asp 
        35                  40                  45              


Glu Met Arg Ala Leu Ala Gly Asn Pro Lys Ala Thr Pro Pro Gln Ile 
    50                  55                  60                  


Val Asn Gly Asp Gln Tyr Cys Gly Asp Tyr Glu Leu Phe Val Glu Ala 
65                  70                  75                  80  


Val Glu Gln Asn Thr Leu Gln Glu Phe Leu Lys Leu Ala 
                85                  90              


<210>  1251
<211>  144
<212>  PRT
<213>  Human

<400>  1251

Met Tyr Ser Glu Ile Gln Arg Glu Arg Ala Asp Ile Gly Gly Leu Met 
1               5                   10                  15      


Ala Arg Pro Glu Tyr Arg Glu Trp Asn Pro Glu Leu Ile Lys Pro Lys 
            20                  25                  30          


Lys Leu Leu Asn Pro Val Lys Ala Ser Arg Ser His Gln Glu Leu His 
        35                  40                  45              


Arg Glu Leu Leu Met Asn His Arg Arg Gly Leu Gly Val Asp Ser Lys 
    50                  55                  60                  


Pro Glu Leu Gln Arg Val Leu Glu His Arg Arg Arg Asn Gln Leu Ile 
65                  70                  75                  80  


Lys Lys Lys Lys Glu Glu Leu Glu Ala Lys Arg Leu Gln Cys Pro Phe 
                85                  90                  95      


Glu Gln Glu Leu Leu Arg Arg Gln Gln Arg Leu Asn Gln Leu Glu Lys 
            100                 105                 110         


Pro Pro Glu Lys Glu Glu Asp His Ala Pro Glu Phe Ile Lys Val Arg 
        115                 120                 125             


Glu Asn Leu Arg Arg Ile Ala Thr Leu Thr Ser Glu Glu Arg Glu Leu 
    130                 135                 140                 


<210>  1252
<211>  1016
<212>  PRT
<213>  Human

<400>  1252

Met Ser Gln Gly Pro Pro Thr Gly Glu Ser Ser Glu Pro Glu Ala Lys 
1               5                   10                  15      


Val Leu His Thr Lys Arg Leu Tyr Arg Ala Val Val Glu Ala Val His 
            20                  25                  30          


Arg Leu Asp Leu Ile Leu Cys Asn Lys Thr Ala Tyr Gln Glu Val Phe 
        35                  40                  45              


Lys Pro Glu Asn Ile Ser Leu Arg Asn Lys Leu Arg Glu Leu Cys Val 
    50                  55                  60                  


Lys Leu Met Phe Leu His Pro Val Asp Tyr Gly Arg Lys Ala Glu Glu 
65                  70                  75                  80  


Leu Leu Trp Arg Lys Val Tyr Tyr Glu Val Ile Gln Leu Ile Lys Thr 
                85                  90                  95      


Asn Lys Lys His Ile His Ser Arg Ser Thr Leu Glu Cys Ala Tyr Arg 
            100                 105                 110         


Thr His Leu Val Ala Gly Ile Gly Phe Tyr Gln His Leu Leu Leu Tyr 
        115                 120                 125             


Ile Gln Ser His Tyr Gln Leu Glu Leu Gln Cys Cys Ile Asp Trp Thr 
    130                 135                 140                 


His Val Thr Asp Pro Leu Ile Gly Cys Lys Lys Pro Val Ser Ala Ser 
145                 150                 155                 160 


Gly Lys Glu Met Asp Trp Ala Gln Met Ala Cys His Arg Cys Leu Val 
                165                 170                 175     


Tyr Leu Gly Asp Leu Ser Arg Tyr Gln Asn Glu Leu Ala Gly Val Asp 
            180                 185                 190         


Thr Glu Leu Leu Ala Glu Arg Phe Tyr Tyr Gln Ala Leu Ser Val Ala 
        195                 200                 205             


Pro Gln Ile Gly Met Pro Phe Asn Gln Leu Gly Thr Leu Ala Gly Ser 
    210                 215                 220                 


Lys Tyr Tyr Asn Val Glu Ala Met Tyr Cys Tyr Leu Arg Cys Ile Gln 
225                 230                 235                 240 


Ser Glu Val Ser Phe Glu Gly Ala Tyr Gly Asn Leu Lys Arg Leu Tyr 
                245                 250                 255     


Asp Lys Ala Ala Lys Met Tyr His Gln Leu Lys Lys Cys Glu Thr Arg 
            260                 265                 270         


Lys Leu Ser Pro Gly Lys Lys Arg Cys Lys Asp Ile Lys Arg Leu Leu 
        275                 280                 285             


Val Asn Phe Met Tyr Leu Gln Ser Leu Leu Gln Pro Lys Ser Ser Ser 
    290                 295                 300                 


Val Asp Ser Glu Leu Thr Ser Leu Cys Gln Ser Val Leu Glu Asp Phe 
305                 310                 315                 320 


Asn Leu Cys Leu Phe Tyr Leu Pro Ser Ser Pro Asn Leu Ser Leu Ala 
                325                 330                 335     


Ser Glu Asp Glu Glu Glu Tyr Glu Ser Gly Tyr Ala Phe Leu Pro Asp 
            340                 345                 350         


Leu Leu Ile Phe Gln Met Val Ile Ile Cys Leu Met Cys Val His Ser 
        355                 360                 365             


Leu Glu Arg Ala Gly Ser Lys Gln Tyr Ser Ala Ala Ile Ala Phe Thr 
    370                 375                 380                 


Leu Ala Leu Phe Ser His Leu Val Asn His Val Asn Ile Arg Leu Gln 
385                 390                 395                 400 


Ala Glu Leu Glu Glu Gly Glu Asn Pro Val Pro Ala Phe Gln Ser Asp 
                405                 410                 415     


Gly Thr Asp Glu Pro Glu Ser Lys Glu Pro Val Glu Lys Glu Glu Glu 
            420                 425                 430         


Pro Asp Pro Glu Pro Pro Pro Val Thr Pro Gln Val Gly Glu Gly Arg 
        435                 440                 445             


Lys Ser Arg Lys Phe Ser Arg Leu Ser Cys Leu Arg Arg Arg Arg His 
    450                 455                 460                 


Pro Pro Lys Val Gly Asp Asp Ser Asp Leu Ser Glu Gly Phe Glu Ser 
465                 470                 475                 480 


Asp Ser Ser His Asp Ser Ala Arg Ala Ser Glu Gly Ser Asp Ser Gly 
                485                 490                 495     


Ser Asp Lys Ser Leu Glu Gly Gly Gly Thr Ala Phe Asp Ala Glu Thr 
            500                 505                 510         


Asp Ser Glu Met Asn Ser Gln Glu Ser Arg Ser Asp Leu Glu Asp Met 
        515                 520                 525             


Glu Glu Glu Glu Gly Thr Arg Ser Pro Thr Leu Glu Pro Pro Arg Gly 
    530                 535                 540                 


Arg Ser Glu Ala Pro Asp Ser Leu Asn Gly Pro Leu Gly Pro Ser Glu 
545                 550                 555                 560 


Ala Ser Ile Ala Ser Asn Leu Gln Ala Met Ser Thr Gln Met Phe Gln 
                565                 570                 575     


Thr Lys Arg Cys Phe Arg Leu Ala Pro Thr Phe Ser Asn Leu Leu Leu 
            580                 585                 590         


Gln Pro Thr Thr Asn Pro His Thr Ser Ala Ser His Arg Pro Cys Val 
        595                 600                 605             


Asn Gly Asp Val Asp Lys Pro Ser Glu Pro Ala Ser Glu Glu Gly Ser 
    610                 615                 620                 


Glu Ser Glu Gly Ser Glu Ser Ser Gly Arg Ser Cys Arg Asn Glu Arg 
625                 630                 635                 640 


Ser Ile Gln Glu Lys Leu Gln Val Leu Met Ala Glu Gly Leu Leu Pro 
                645                 650                 655     


Ala Val Lys Val Phe Leu Asp Trp Leu Arg Thr Asn Pro Asp Leu Ile 
            660                 665                 670         


Ile Val Cys Ala Gln Ser Ser Gln Ser Leu Trp Asn Arg Leu Ser Val 
        675                 680                 685             


Leu Leu Asn Leu Leu Pro Ala Ala Gly Glu Leu Gln Glu Ser Gly Leu 
    690                 695                 700                 


Ala Leu Cys Pro Glu Val Gln Asp Leu Leu Glu Gly Cys Glu Leu Pro 
705                 710                 715                 720 


Asp Leu Pro Ser Ser Leu Leu Leu Pro Glu Asp Met Ala Leu Arg Asn 
                725                 730                 735     


Leu Pro Pro Leu Arg Ala Ala His Arg Arg Phe Asn Phe Asp Thr Asp 
            740                 745                 750         


Arg Pro Leu Leu Ser Thr Leu Glu Glu Ser Val Val Arg Ile Cys Cys 
        755                 760                 765             


Ile Arg Ser Phe Gly His Phe Ile Ala Arg Leu Gln Gly Ser Ile Leu 
    770                 775                 780                 


Gln Phe Asn Pro Glu Val Gly Ile Phe Val Ser Ile Ala Gln Ser Glu 
785                 790                 795                 800 


Gln Glu Ser Leu Leu Gln Gln Ala Gln Ala Gln Phe Arg Met Ala Gln 
                805                 810                 815     


Glu Glu Ala Arg Arg Asn Arg Leu Met Arg Asp Met Ala Gln Leu Arg 
            820                 825                 830         


Leu Gln Leu Glu Val Ser Gln Leu Glu Gly Ser Leu Gln Gln Pro Lys 
        835                 840                 845             


Ala Gln Ser Ala Met Ser Pro Tyr Leu Val Pro Asp Thr Gln Ala Leu 
    850                 855                 860                 


Cys His His Leu Pro Val Ile Arg Gln Leu Ala Thr Ser Gly Arg Phe 
865                 870                 875                 880 


Ile Val Ile Ile Pro Arg Thr Val Ile Asp Gly Leu Asp Leu Leu Lys 
                885                 890                 895     


Lys Glu His Pro Gly Ala Arg Asp Gly Ile Arg Tyr Leu Glu Ala Glu 
            900                 905                 910         


Phe Lys Lys Gly Asn Arg Tyr Ile Arg Cys Gln Lys Glu Val Gly Lys 
        915                 920                 925             


Ser Phe Glu Arg His Lys Leu Lys Arg Gln Asp Ala Asp Ala Trp Thr 
    930                 935                 940                 


Leu Tyr Lys Ile Leu Asp Ser Cys Lys Gln Leu Thr Leu Ala Gln Gly 
945                 950                 955                 960 


Ala Gly Glu Glu Asp Pro Ser Gly Met Val Thr Ile Ile Thr Gly Leu 
                965                 970                 975     


Pro Leu Asp Asn Pro Ser Val Leu Ser Gly Pro Met Gln Ala Ala Leu 
            980                 985                 990         


Gln Ala Ala Ala His Ala Ser Val  Asp Ile Lys Asn Val  Leu Asp Phe 
        995                 1000                 1005             


Tyr Lys  Gln Trp Lys Glu Ile  Gly 
    1010                 1015     


<210>  1253
<211>  624
<212>  PRT
<213>  Human

<400>  1253

Met Ala Leu Arg Ala Arg Ala Leu Tyr Asp Phe Arg Ser Glu Asn Pro 
1               5                   10                  15      


Gly Glu Ile Ser Leu Arg Glu His Glu Val Leu Ser Leu Cys Ser Glu 
            20                  25                  30          


Gln Asp Ile Glu Gly Trp Leu Glu Gly Val Asn Ser Arg Gly Asp Arg 
        35                  40                  45              


Gly Leu Phe Pro Ala Ser Tyr Val Gln Val Ile Arg Ala Pro Glu Pro 
    50                  55                  60                  


Gly Pro Ala Gly Asp Gly Gly Pro Gly Ala Pro Ala Arg Tyr Ala Asn 
65                  70                  75                  80  


Val Pro Pro Gly Gly Phe Glu Pro Leu Pro Val Ala Pro Pro Ala Ser 
                85                  90                  95      


Phe Lys Pro Pro Pro Asp Ala Phe Gln Ala Leu Leu Gln Pro Gln Gln 
            100                 105                 110         


Ala Pro Pro Pro Ser Thr Phe Gln Pro Pro Gly Ala Gly Phe Pro Tyr 
        115                 120                 125             


Gly Gly Gly Ala Leu Gln Pro Ser Pro Gln Gln Leu Tyr Gly Gly Tyr 
    130                 135                 140                 


Gln Ala Ser Gln Gly Ser Asp Asp Asp Trp Asp Asp Glu Trp Asp Asp 
145                 150                 155                 160 


Ser Ser Thr Val Ala Asp Glu Pro Gly Ala Leu Gly Ser Gly Ala Tyr 
                165                 170                 175     


Pro Asp Leu Asp Gly Ser Ser Ser Ala Gly Val Gly Ala Ala Gly Arg 
            180                 185                 190         


Tyr Arg Leu Ser Thr Arg Ser Asp Leu Ser Leu Gly Ser Arg Gly Gly 
        195                 200                 205             


Ser Val Pro Pro Gln His His Pro Ser Gly Pro Lys Ser Ser Ala Thr 
    210                 215                 220                 


Val Ser Arg Asn Leu Asn Arg Phe Ser Thr Phe Val Lys Ser Gly Gly 
225                 230                 235                 240 


Glu Ala Phe Val Leu Gly Glu Ala Ser Gly Phe Val Lys Asp Gly Asp 
                245                 250                 255     


Lys Leu Cys Val Val Leu Gly Pro Tyr Gly Pro Glu Trp Gln Glu Asn 
            260                 265                 270         


Pro Tyr Pro Phe Gln Cys Thr Ile Asp Asp Pro Thr Lys Gln Thr Lys 
        275                 280                 285             


Phe Lys Gly Met Lys Ser Tyr Ile Ser Tyr Lys Leu Val Pro Thr His 
    290                 295                 300                 


Thr Gln Val Pro Val His Arg Arg Tyr Lys His Phe Asp Trp Leu Tyr 
305                 310                 315                 320 


Ala Arg Leu Ala Glu Lys Phe Pro Val Ile Ser Val Pro His Leu Pro 
                325                 330                 335     


Glu Lys Gln Ala Thr Gly Arg Phe Glu Glu Asp Phe Ile Ser Lys Arg 
            340                 345                 350         


Arg Lys Gly Leu Ile Trp Trp Met Asn His Met Ala Ser His Pro Val 
        355                 360                 365             


Leu Ala Gln Cys Asp Val Phe Gln His Phe Leu Thr Cys Pro Ser Ser 
    370                 375                 380                 


Thr Asp Glu Lys Ala Trp Lys Gln Gly Lys Arg Lys Ala Glu Lys Asp 
385                 390                 395                 400 


Glu Met Val Gly Ala Asn Phe Phe Leu Thr Leu Ser Thr Pro Pro Ala 
                405                 410                 415     


Ala Ala Leu Asp Leu Gln Glu Val Glu Ser Lys Ile Asp Gly Phe Lys 
            420                 425                 430         


Cys Phe Thr Lys Lys Met Asp Asp Ser Ala Leu Gln Leu Asn His Thr 
        435                 440                 445             


Ala Asn Glu Phe Ala Arg Lys Gln Val Thr Gly Phe Lys Lys Glu Tyr 
    450                 455                 460                 


Gln Lys Val Gly Gln Ser Phe Arg Gly Leu Ser Gln Ala Phe Glu Leu 
465                 470                 475                 480 


Asp Gln Gln Ala Phe Ser Val Gly Leu Asn Gln Ala Ile Ala Phe Thr 
                485                 490                 495     


Gly Asp Ala Tyr Asp Ala Ile Gly Glu Leu Phe Ala Glu Gln Pro Arg 
            500                 505                 510         


Gln Asp Leu Asp Pro Val Met Asp Leu Leu Ala Leu Tyr Gln Gly His 
        515                 520                 525             


Leu Ala Asn Phe Pro Asp Ile Ile His Val Gln Lys Gly Ala Leu Thr 
    530                 535                 540                 


Lys Val Lys Glu Ser Arg Arg His Val Glu Glu Gly Lys Met Glu Val 
545                 550                 555                 560 


Gln Lys Ala Asp Gly Ile Gln Asp Arg Cys Asn Thr Ile Ser Phe Ala 
                565                 570                 575     


Thr Leu Ala Glu Ile His His Phe His Gln Ile Arg Val Arg Asp Phe 
            580                 585                 590         


Lys Ser Gln Met Gln His Phe Leu Gln Gln Gln Ile Ile Phe Phe Gln 
        595                 600                 605             


Lys Val Thr Gln Lys Leu Glu Glu Ala Leu His Lys Tyr Asp Ser Val 
    610                 615                 620                 


<210>  1254
<211>  714
<212>  PRT
<213>  Human

<400>  1254

Met Ala Arg Ala Gly Ser Cys Gly Gly Ala Ala Ala Gly Ala Gly Arg 
1               5                   10                  15      


Pro Glu Pro Trp Glu Leu Ser Leu Glu Glu Val Leu Lys Ala Tyr Glu 
            20                  25                  30          


Gln Pro Leu Asn Glu Glu Gln Ala Trp Ala Val Cys Phe Gln Gly Cys 
        35                  40                  45              


Arg Gly Leu Arg Gly Ser Pro Gly Arg Arg Leu Arg Asp Thr Gly Asp 
    50                  55                  60                  


Leu Leu Leu Arg Gly Asp Gly Ser Val Gly Ala Arg Glu Pro Glu Ala 
65                  70                  75                  80  


Ala Glu Pro Ala Thr Met Val Val Pro Leu Ala Ser Ser Glu Ala Gln 
                85                  90                  95      


Thr Val Gln Ser Leu Gly Phe Ala Ile Tyr Arg Ala Leu Asp Trp Gly 
            100                 105                 110         


Leu Asp Glu Ser Glu Glu Arg Glu Leu Ser Pro Gln Leu Glu Arg Leu 
        115                 120                 125             


Ile Asp Leu Met Ala Asn Asn Asp Ser Glu Asp Ser Gly Cys Gly Ala 
    130                 135                 140                 


Ala Asp Glu Gly Tyr Gly Gly Pro Glu Glu Glu Glu Glu Ala Glu Gly 
145                 150                 155                 160 


Val Pro Arg Ser Val Arg Thr Phe Ala Gln Ala Met Arg Leu Cys Ala 
                165                 170                 175     


Ala Arg Leu Thr Asp Pro Arg Gly Ala Gln Ala His Tyr Gln Ala Val 
            180                 185                 190         


Cys Arg Ala Leu Phe Val Glu Thr Leu Glu Leu Arg Ala Phe Leu Ala 
        195                 200                 205             


Arg Val Arg Glu Ala Lys Glu Met Leu Gln Lys Leu Arg Glu Asp Glu 
    210                 215                 220                 


Pro His Leu Glu Thr Pro Arg Ala Glu Leu Asp Ser Leu Gly His Thr 
225                 230                 235                 240 


Asp Trp Ala Arg Leu Trp Val Gln Leu Met Arg Glu Leu Arg Arg Gly 
                245                 250                 255     


Val Lys Leu Lys Lys Val Gln Glu Gln Glu Phe Asn Pro Leu Pro Thr 
            260                 265                 270         


Glu Phe Gln Leu Thr Pro Phe Glu Met Leu Met Gln Asp Ile Arg Ala 
        275                 280                 285             


Arg Asn Tyr Lys Leu Arg Lys Val Met Val Asp Gly Asp Ile Pro Pro 
    290                 295                 300                 


Arg Val Lys Lys Asp Ala His Glu Leu Ile Leu Asp Phe Ile Arg Ser 
305                 310                 315                 320 


Arg Pro Pro Leu Lys Gln Val Ser Glu Arg Arg Leu Arg Pro Leu Pro 
                325                 330                 335     


Pro Lys Gln Arg Ser Leu His Glu Lys Ile Leu Glu Glu Ile Lys Gln 
            340                 345                 350         


Glu Arg Arg Leu Arg Pro Val Arg Gly Glu Gly Trp Ala Ala Arg Gly 
        355                 360                 365             


Phe Gly Ser Leu Pro Cys Ile Leu Asn Ala Cys Ser Gly Asp Ala Lys 
    370                 375                 380                 


Ser Thr Ser Cys Ile Asn Leu Ser Val Thr Asp Ala Gly Gly Ser Ala 
385                 390                 395                 400 


Gln Arg Pro Arg Pro Arg Val Leu Leu Lys Ala Pro Thr Leu Ala Glu 
                405                 410                 415     


Met Glu Glu Met Asn Thr Ser Glu Glu Glu Glu Ser Pro Cys Gly Glu 
            420                 425                 430         


Val Thr Leu Lys Arg Asp Arg Ser Phe Ser Glu His Asp Leu Ala Gln 
        435                 440                 445             


Leu Arg Ser Glu Val Ala Ser Gly Leu Gln Ser Ala Thr His Pro Pro 
    450                 455                 460                 


Gly Gly Thr Glu Pro Pro Arg Pro Arg Ala Gly Ser Ala His Val Trp 
465                 470                 475                 480 


Arg Pro Gly Ser Arg Asp Gln Gly Thr Cys Pro Ala Ser Val Ser Asp 
                485                 490                 495     


Pro Ser His Pro Leu Leu Ser Asn Arg Gly Ser Ser Gly Asp Arg Pro 
            500                 505                 510         


Glu Ala Ser Met Thr Pro Asp Ala Lys His Leu Trp Leu Glu Phe Ser 
        515                 520                 525             


His Pro Val Glu Ser Leu Ala Leu Thr Val Glu Glu Val Met Asp Val 
    530                 535                 540                 


Arg Arg Val Leu Val Lys Ala Glu Met Glu Lys Phe Leu Gln Asn Lys 
545                 550                 555                 560 


Glu Leu Phe Ser Ser Leu Lys Lys Gly Lys Ile Cys Cys Cys Cys Arg 
                565                 570                 575     


Ala Lys Phe Pro Leu Phe Ser Trp Pro Pro Ser Cys Leu Phe Cys Lys 
            580                 585                 590         


Arg Ala Val Cys Thr Ser Cys Ser Ile Lys Met Lys Met Pro Ser Lys 
        595                 600                 605             


Lys Phe Gly His Ile Pro Val Tyr Thr Leu Gly Phe Glu Ser Pro Gln 
    610                 615                 620                 


Arg Val Ser Ala Ala Lys Thr Ala Pro Ile Gln Arg Arg Asp Ile Phe 
625                 630                 635                 640 


Gln Ser Leu Gln Gly Pro Gln Trp Gln Ser Val Glu Glu Ala Phe Pro 
                645                 650                 655     


His Ile Tyr Ser His Gly Cys Val Leu Lys Asp Val Cys Ser Glu Cys 
            660                 665                 670         


Thr Ser Phe Val Ala Asp Val Val Arg Ser Ser Arg Lys Ser Val Asp 
        675                 680                 685             


Val Leu Asn Thr Thr Pro Arg Arg Ser Arg Gln Thr Gln Ser Leu Tyr 
    690                 695                 700                 


Ile Pro Asn Thr Arg Thr Leu Asp Phe Lys 
705                 710                 


<210>  1255
<211>  299
<212>  PRT
<213>  Human

<400>  1255

Met Ala Arg Glu Ile Asp Asn Phe Tyr Pro Glu Arg Phe Thr Tyr His 
1               5                   10                  15      


Asn Val Arg Leu Trp Asp Glu Glu Ser Ala Gln Leu Leu Pro His Trp 
            20                  25                  30          


Lys Glu Thr His Arg Phe Ile Glu Ala Ala Arg Ala Gln Gly Thr His 
        35                  40                  45              


Val Leu Val His Cys Lys Met Gly Val Ser Arg Ser Ala Ala Thr Val 
    50                  55                  60                  


Leu Ala Tyr Ala Met Lys Gln Tyr Glu Cys Ser Leu Glu Gln Ala Leu 
65                  70                  75                  80  


Arg His Val Gln Glu Leu Arg Pro Ile Ala Arg Pro Asn Pro Gly Phe 
                85                  90                  95      


Leu Arg Gln Leu Gln Ile Tyr Gln Gly Ile Leu Thr Ala Ser Arg Gln 
            100                 105                 110         


Ser His Val Trp Glu Gln Lys Val Gly Gly Val Ser Pro Glu Glu His 
        115                 120                 125             


Pro Ala Pro Glu Val Ser Thr Pro Phe Pro Pro Leu Pro Pro Glu Pro 
    130                 135                 140                 


Glu Gly Gly Gly Glu Glu Lys Val Val Gly Met Glu Glu Ser Gln Ala 
145                 150                 155                 160 


Ala Pro Lys Glu Glu Pro Gly Pro Arg Pro Arg Ile Asn Leu Arg Gly 
                165                 170                 175     


Val Met Arg Ser Ile Ser Leu Leu Glu Pro Ser Leu Glu Leu Glu Ser 
            180                 185                 190         


Thr Ser Glu Thr Ser Asp Met Pro Glu Val Phe Ser Ser His Glu Ser 
        195                 200                 205             


Ser His Glu Glu Pro Leu Gln Pro Phe Pro Gln Leu Ala Arg Thr Lys 
    210                 215                 220                 


Gly Gly Gln Gln Val Asp Arg Gly Pro Gln Pro Ala Leu Lys Ser Arg 
225                 230                 235                 240 


Gln Ser Val Val Thr Leu Gln Gly Ser Ala Val Val Ala Asn Arg Thr 
                245                 250                 255     


Gln Ala Phe Gln Glu Gln Glu Gln Gly Gln Gly Gln Gly Gln Gly Glu 
            260                 265                 270         


Pro Cys Ile Ser Ser Thr Pro Arg Phe Arg Lys Val Val Arg Gln Ala 
        275                 280                 285             


Ser Val His Asp Ser Gly Glu Glu Gly Glu Ala 
    290                 295                 


<210>  1256
<211>  414
<212>  PRT
<213>  Human

<400>  1256

Met Ile Pro Leu Glu Lys Pro Gly Ser Gly Gly Ser Ser Pro Gly Ala 
1               5                   10                  15      


Thr Ser Gly Ser Gly Arg Ala Gly Arg Gly Leu Ser Gly Pro Cys Arg 
            20                  25                  30          


Pro Pro Pro Pro Pro Gln Ala Arg Gly Leu Leu Thr Glu Ile Arg Ala 
        35                  40                  45              


Val Val Arg Thr Glu Pro Phe Gln Asp Gly Tyr Ser Leu Cys Pro Gly 
    50                  55                  60                  


Arg Glu Leu Gly Arg Gly Lys Phe Ala Val Val Arg Lys Cys Ile Lys 
65                  70                  75                  80  


Lys Asp Ser Gly Lys Glu Phe Ala Ala Lys Phe Met Arg Lys Arg Arg 
                85                  90                  95      


Lys Gly Gln Asp Cys Arg Met Glu Ile Ile His Glu Ile Ala Val Leu 
            100                 105                 110         


Glu Leu Ala Gln Asp Asn Pro Trp Val Ile Asn Leu His Glu Val Tyr 
        115                 120                 125             


Glu Thr Ala Ser Glu Met Ile Leu Val Leu Glu Tyr Ala Ala Gly Gly 
    130                 135                 140                 


Glu Ile Phe Asp Gln Cys Val Ala Asp Arg Glu Glu Ala Phe Lys Glu 
145                 150                 155                 160 


Lys Asp Val Gln Arg Leu Met Arg Gln Ile Leu Glu Gly Val His Phe 
                165                 170                 175     


Leu His Thr Arg Asp Val Val His Leu Asp Leu Lys Pro Gln Asn Ile 
            180                 185                 190         


Leu Leu Thr Ser Glu Ser Pro Leu Gly Asp Ile Lys Ile Val Asp Phe 
        195                 200                 205             


Gly Leu Ser Arg Ile Leu Lys Asn Ser Glu Glu Leu Arg Glu Ile Met 
    210                 215                 220                 


Gly Thr Pro Glu Tyr Val Ala Pro Glu Ile Leu Ser Tyr Asp Pro Ile 
225                 230                 235                 240 


Ser Met Ala Thr Asp Met Trp Ser Ile Gly Val Leu Thr Tyr Val Met 
                245                 250                 255     


Leu Thr Gly Ile Ser Pro Phe Leu Gly Asn Asp Lys Gln Glu Thr Phe 
            260                 265                 270         


Leu Asn Ile Ser Gln Met Asn Leu Ser Tyr Ser Glu Glu Glu Phe Asp 
        275                 280                 285             


Val Leu Ser Glu Ser Ala Val Asp Phe Ile Arg Thr Leu Leu Val Lys 
    290                 295                 300                 


Lys Pro Glu Asp Arg Ala Thr Ala Glu Glu Cys Leu Lys His Pro Trp 
305                 310                 315                 320 


Leu Thr Gln Ser Ser Ile Gln Glu Pro Ser Phe Arg Met Glu Lys Ala 
                325                 330                 335     


Leu Glu Glu Ala Asn Ala Leu Gln Glu Gly His Ser Val Pro Glu Ile 
            340                 345                 350         


Asn Ser Asp Thr Asp Lys Ser Glu Thr Lys Glu Ser Ile Val Thr Glu 
        355                 360                 365             


Glu Leu Ile Val Val Thr Ser Tyr Thr Leu Gly Gln Cys Arg Gln Ser 
    370                 375                 380                 


Glu Lys Glu Lys Met Glu Gln Lys Ala Ile Ser Lys Arg Phe Lys Phe 
385                 390                 395                 400 


Glu Glu Pro Leu Leu Gln Glu Ile Pro Gly Glu Phe Ile Tyr 
                405                 410                 


<210>  1257
<211>  885
<212>  PRT
<213>  Human

<400>  1257

Met Lys Trp Leu Gly Glu Ser Lys Asn Met Val Val Asn Gly Arg Arg 
1               5                   10                  15      


Asn Gly Gly Lys Leu Ser Asn Asp His Gln Gln Asn Gln Ser Lys Leu 
            20                  25                  30          


Gln His Thr Gly Lys Asp Thr Leu Lys Ala Gly Lys Asn Ala Val Glu 
        35                  40                  45              


Arg Arg Ser Asn Arg Cys Asn Gly Asn Ser Gly Phe Glu Gly Gln Ser 
    50                  55                  60                  


Arg Tyr Val Pro Ser Ser Gly Met Ser Ala Lys Glu Leu Cys Glu Asn 
65                  70                  75                  80  


Asp Asp Leu Ala Thr Ser Leu Val Leu Asp Pro Tyr Leu Gly Phe Gln 
                85                  90                  95      


Thr His Lys Met Asn Thr Ser Ala Phe Pro Ser Arg Ser Ser Arg His 
            100                 105                 110         


Phe Ser Lys Ser Asp Ser Phe Ser His Asn Asn Pro Val Arg Phe Arg 
        115                 120                 125             


Pro Ile Lys Gly Arg Gln Glu Glu Leu Lys Glu Val Ile Glu Arg Phe 
    130                 135                 140                 


Lys Lys Asp Glu His Leu Glu Lys Ala Phe Lys Cys Leu Thr Ser Gly 
145                 150                 155                 160 


Glu Trp Ala Arg His Tyr Phe Leu Asn Lys Asn Lys Met Gln Glu Lys 
                165                 170                 175     


Leu Phe Lys Glu His Val Phe Ile Tyr Leu Arg Met Phe Ala Thr Asp 
            180                 185                 190         


Ser Gly Phe Glu Ile Leu Pro Cys Asn Arg Tyr Ser Ser Glu Gln Asn 
        195                 200                 205             


Gly Ala Lys Ile Val Ala Thr Lys Glu Trp Lys Arg Asn Asp Lys Ile 
    210                 215                 220                 


Glu Leu Leu Val Gly Cys Ile Ala Glu Leu Ser Glu Ile Glu Glu Asn 
225                 230                 235                 240 


Met Leu Leu Arg His Gly Glu Asn Asp Phe Ser Val Met Tyr Ser Thr 
                245                 250                 255     


Arg Lys Asn Cys Ala Gln Leu Trp Leu Gly Pro Ala Ala Phe Ile Asn 
            260                 265                 270         


His Asp Cys Arg Pro Asn Cys Lys Phe Val Ser Thr Gly Arg Asp Thr 
        275                 280                 285             


Ala Cys Val Lys Ala Leu Arg Asp Ile Glu Pro Gly Glu Glu Ile Ser 
    290                 295                 300                 


Cys Tyr Tyr Gly Asp Gly Phe Phe Gly Glu Asn Asn Glu Phe Cys Glu 
305                 310                 315                 320 


Cys Tyr Thr Cys Glu Arg Arg Gly Thr Gly Ala Phe Lys Ser Arg Val 
                325                 330                 335     


Gly Leu Pro Ala Pro Ala Pro Val Ile Asn Ser Lys Tyr Gly Leu Arg 
            340                 345                 350         


Glu Thr Asp Lys Arg Leu Asn Arg Leu Lys Lys Leu Gly Asp Ser Ser 
        355                 360                 365             


Lys Asn Ser Asp Ser Gln Ser Val Ser Ser Asn Thr Asp Ala Asp Thr 
    370                 375                 380                 


Thr Gln Glu Lys Asn Asn Ala Thr Ser Asn Arg Lys Ser Ser Val Gly 
385                 390                 395                 400 


Val Lys Lys Asn Ser Lys Ser Arg Thr Leu Thr Arg Gln Ser Met Ser 
                405                 410                 415     


Arg Ile Pro Ala Ser Ser Asn Ser Thr Ser Ser Lys Leu Thr His Ile 
            420                 425                 430         


Asn Asn Ser Arg Val Pro Lys Lys Leu Lys Lys Pro Ala Lys Pro Leu 
        435                 440                 445             


Leu Ser Lys Ile Lys Leu Arg Asn His Cys Lys Arg Leu Glu Gln Lys 
    450                 455                 460                 


Asn Ala Ser Arg Lys Leu Glu Met Gly Asn Leu Val Leu Lys Glu Pro 
465                 470                 475                 480 


Lys Val Val Leu Tyr Lys Asn Leu Pro Ile Lys Lys Asp Lys Glu Pro 
                485                 490                 495     


Glu Gly Pro Ala Gln Ala Ala Val Ala Ser Gly Cys Leu Thr Arg His 
            500                 505                 510         


Ala Ala Arg Glu His Arg Gln Asn Pro Val Arg Gly Ala His Ser Gln 
        515                 520                 525             


Gly Glu Ser Ser Pro Cys Thr Tyr Ile Thr Arg Arg Ser Val Arg Thr 
    530                 535                 540                 


Arg Thr Asn Leu Lys Glu Ala Ser Asp Ile Lys Leu Glu Pro Asn Thr 
545                 550                 555                 560 


Leu Asn Gly Tyr Lys Ser Ser Val Thr Glu Pro Cys Pro Asp Ser Gly 
                565                 570                 575     


Glu Gln Leu Gln Pro Ala Pro Val Leu Gln Glu Glu Glu Leu Ala His 
            580                 585                 590         


Glu Thr Ala Gln Lys Gly Glu Ala Lys Cys His Lys Ser Asp Thr Gly 
        595                 600                 605             


Met Ser Lys Lys Lys Ser Arg Gln Gly Lys Leu Val Lys Gln Phe Ala 
    610                 615                 620                 


Lys Ile Glu Glu Ser Thr Pro Val His Asp Ser Pro Gly Lys Asp Asp 
625                 630                 635                 640 


Ala Val Pro Asp Leu Met Gly Pro His Ser Asp Gln Gly Glu His Ser 
                645                 650                 655     


Gly Thr Val Gly Val Pro Val Ser Tyr Thr Asp Cys Ala Pro Ser Pro 
            660                 665                 670         


Val Gly Cys Ser Val Val Thr Ser Asp Ser Phe Lys Thr Lys Asp Ser 
        675                 680                 685             


Phe Arg Thr Ala Lys Ser Lys Lys Lys Arg Arg Ile Thr Arg Tyr Asp 
    690                 695                 700                 


Ala Gln Leu Ile Leu Glu Asn Asn Ser Gly Ile Pro Lys Leu Thr Leu 
705                 710                 715                 720 


Arg Arg Arg His Asp Ser Ser Ser Lys Thr Asn Asp Gln Glu Asn Asp 
                725                 730                 735     


Gly Met Asn Ser Ser Lys Ile Ser Ile Lys Leu Ser Lys Asp His Asp 
            740                 745                 750         


Asn Asp Asn Asn Leu Tyr Val Ala Lys Leu Asn Asn Gly Phe Asn Ser 
        755                 760                 765             


Gly Ser Gly Ser Ser Ser Thr Lys Leu Lys Ile Gln Leu Lys Arg Asp 
    770                 775                 780                 


Glu Glu Asn Arg Gly Ser Tyr Thr Glu Gly Leu His Glu Asn Gly Val 
785                 790                 795                 800 


Cys Cys Ser Asp Pro Leu Ser Leu Leu Glu Ser Arg Met Glu Val Asp 
                805                 810                 815     


Asp Tyr Ser Gln Tyr Glu Glu Glu Ser Thr Asp Asp Ser Ser Ser Ser 
            820                 825                 830         


Glu Gly Asp Glu Glu Glu Asp Asp Tyr Asp Asp Asp Phe Glu Asp Asp 
        835                 840                 845             


Phe Ile Pro Leu Pro Pro Ala Lys Arg Leu Arg Leu Ile Val Gly Lys 
    850                 855                 860                 


Asp Ser Ile Asp Ile Asp Ile Ser Ser Arg Arg Arg Glu Asp Gln Ser 
865                 870                 875                 880 


Leu Arg Leu Asn Ala 
                885 


<210>  1258
<211>  108
<212>  PRT
<213>  Human

<400>  1258

Met Ala Asp Pro Arg Val Arg Gln Ile Lys Ile Lys Thr Gly Val Val 
1               5                   10                  15      


Lys Arg Leu Val Lys Glu Lys Val Met Tyr Glu Lys Glu Ala Lys Gln 
            20                  25                  30          


Gln Glu Glu Lys Ile Glu Lys Met Arg Ala Glu Asp Gly Glu Asn Tyr 
        35                  40                  45              


Asp Ile Lys Lys Gln Ala Glu Ile Leu Gln Glu Ser Arg Met Met Ile 
    50                  55                  60                  


Pro Asp Cys Gln Arg Arg Leu Glu Ala Ala Tyr Leu Asp Leu Gln Arg 
65                  70                  75                  80  


Ile Leu Glu Asn Glu Lys Asp Leu Glu Glu Ala Glu Glu Tyr Lys Glu 
                85                  90                  95      


Ala Arg Leu Val Leu Asp Ser Val Lys Leu Glu Ala 
            100                 105             


<210>  1259
<211>  502
<212>  PRT
<213>  Human

<400>  1259

Met Ala Trp Ala Leu Lys Leu Pro Leu Ala Asp Glu Val Ile Glu Ser 
1               5                   10                  15      


Gly Leu Val Gln Asp Phe Asp Ala Ser Leu Ser Gly Ile Gly Gln Glu 
            20                  25                  30          


Leu Gly Ala Gly Ala Tyr Ser Met Ser Asp Val Leu Ala Leu Pro Ile 
        35                  40                  45              


Phe Lys Gln Glu Glu Ser Ser Leu Pro Pro Asp Asn Glu Asn Lys Ile 
    50                  55                  60                  


Leu Pro Phe Gln Tyr Val Leu Cys Ala Ala Thr Ser Pro Ala Val Lys 
65                  70                  75                  80  


Leu His Asp Glu Thr Leu Thr Tyr Leu Asn Gln Gly Gln Ser Tyr Glu 
                85                  90                  95      


Ile Arg Met Leu Asp Asn Arg Lys Leu Gly Glu Leu Pro Glu Ile Asn 
            100                 105                 110         


Gly Lys Leu Val Lys Ser Ile Phe Arg Val Val Phe His Asp Arg Arg 
        115                 120                 125             


Leu Gln Tyr Thr Glu His Gln Gln Leu Glu Gly Trp Arg Trp Asn Arg 
    130                 135                 140                 


Pro Gly Asp Arg Ile Leu Asp Ile Asp Ile Pro Met Ser Val Gly Ile 
145                 150                 155                 160 


Ile Asp Pro Arg Ala Asn Pro Thr Gln Leu Asn Thr Val Glu Phe Leu 
                165                 170                 175     


Trp Asp Pro Ala Lys Arg Thr Ser Val Phe Ile Gln Val His Cys Ile 
            180                 185                 190         


Ser Thr Glu Phe Thr Met Arg Lys His Gly Gly Glu Lys Gly Val Pro 
        195                 200                 205             


Phe Arg Val Gln Ile Asp Thr Phe Lys Glu Asn Glu Asn Gly Glu Tyr 
    210                 215                 220                 


Thr Glu His Leu His Ser Ala Ser Cys Gln Ile Lys Val Phe Lys Pro 
225                 230                 235                 240 


Lys Gly Ala Asp Arg Lys Gln Lys Thr Asp Arg Glu Lys Met Glu Lys 
                245                 250                 255     


Arg Thr Pro His Glu Lys Glu Lys Tyr Gln Pro Ser Tyr Glu Thr Thr 
            260                 265                 270         


Ile Leu Thr Glu Cys Ser Pro Trp Pro Glu Ile Thr Tyr Val Asn Asn 
        275                 280                 285             


Ser Pro Ser Pro Gly Phe Asn Ser Ser His Ser Ser Phe Ser Leu Gly 
    290                 295                 300                 


Glu Gly Asn Gly Ser Pro Asn His Gln Pro Glu Pro Pro Pro Pro Val 
305                 310                 315                 320 


Thr Asp Asn Leu Leu Pro Thr Thr Thr Pro Gln Glu Ala Gln Gln Trp 
                325                 330                 335     


Leu His Arg Asn Arg Phe Ser Thr Phe Thr Arg Leu Phe Thr Asn Phe 
            340                 345                 350         


Ser Gly Ala Asp Leu Leu Lys Leu Thr Arg Asp Asp Val Ile Gln Ile 
        355                 360                 365             


Cys Gly Pro Ala Asp Gly Ile Arg Leu Phe Asn Ala Leu Lys Gly Arg 
    370                 375                 380                 


Met Val Arg Pro Arg Leu Thr Ile Tyr Val Cys Gln Glu Ser Leu Gln 
385                 390                 395                 400 


Leu Arg Glu Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Lys His Glu 
                405                 410                 415     


Asp Gly Asp Ser Asn Gly Thr Phe Phe Val Tyr His Ala Ile Tyr Leu 
            420                 425                 430         


Glu Glu Leu Thr Ala Val Glu Leu Thr Glu Lys Ile Ala Gln Leu Phe 
        435                 440                 445             


Ser Ile Ser Pro Cys Gln Ile Ser Gln Ile Tyr Lys Gln Gly Pro Thr 
    450                 455                 460                 


Gly Ile His Val Leu Ile Ser Asp Glu Met Ile Gln Asn Phe Gln Glu 
465                 470                 475                 480 


Glu Ala Cys Phe Ile Leu Asp Thr Met Lys Ala Glu Thr Asn Asp Ser 
                485                 490                 495     


Tyr His Ile Ile Leu Lys 
            500         


<210>  1260
<211>  575
<212>  PRT
<213>  Human

<400>  1260

Met Ser His Ala Ala Glu Pro Ala Arg Asp Gly Val Glu Ala Ser Ala 
1               5                   10                  15      


Glu Gly Pro Arg Ala Val Phe Val Leu Leu Glu Glu Arg Arg Pro Ala 
            20                  25                  30          


Asp Ser Ala Gln Leu Leu Ser Leu Asn Ser Leu Leu Pro Glu Ser Gly 
        35                  40                  45              


Ile Val Ala Asp Ile Glu Leu Glu Asn Val Leu Asp Pro Asp Ser Phe 
    50                  55                  60                  


Tyr Glu Leu Lys Ser Gln Pro Leu Pro Leu Arg Ser Ser Leu Pro Ile 
65                  70                  75                  80  


Ser Leu Gln Ala Thr Pro Ala Thr Pro Ala Thr Leu Ser Ala Ser Ser 
                85                  90                  95      


Ser Ala Gly Gly Ser Arg Thr Pro Ala Met Ser Ser Ser Ser Ser Ser 
            100                 105                 110         


Arg Val Leu Leu Arg Gln Gln Leu Met Arg Ala Gln Ala Gln Glu Gln 
        115                 120                 125             


Glu Arg Arg Glu Arg Arg Glu Gln Ala Ala Ala Ala Pro Phe Pro Ser 
    130                 135                 140                 


Pro Ala Pro Ala Ser Pro Ala Ile Ser Val Val Gly Val Ser Ala Gly 
145                 150                 155                 160 


Gly His Thr Leu Ser Arg Pro Pro Pro Ala Gln Val Pro Arg Glu Val 
                165                 170                 175     


Leu Lys Val Gln Thr His Leu Glu Asn Pro Thr Arg Tyr His Leu Gln 
            180                 185                 190         


Gln Ala Arg Arg Gln Gln Val Lys Gln Tyr Leu Ser Thr Thr Leu Gly 
        195                 200                 205             


Pro Lys Leu Ala Ser Gln Ala Leu Thr Pro Pro Pro Gly Pro Ala Ser 
    210                 215                 220                 


Ala Gln Pro Leu Pro Ala Pro Glu Ala Ala His Thr Thr Gly Pro Thr 
225                 230                 235                 240 


Gly Ser Ala Pro Asn Ser Pro Met Ala Leu Leu Thr Ile Gly Ser Ser 
                245                 250                 255     


Ser Glu Lys Glu Ile Asp Asp Val Ile Asp Glu Ile Ile Ser Leu Glu 
            260                 265                 270         


Ser Ser Tyr Asn Asp Glu Met Leu Ser Tyr Leu Pro Gly Gly Thr Thr 
        275                 280                 285             


Gly Leu Gln Leu Pro Ser Thr Leu Pro Val Ser Gly Asn Leu Leu Asp 
    290                 295                 300                 


Val Tyr Ser Ser Gln Gly Val Ala Thr Pro Ala Ile Thr Val Ser Asn 
305                 310                 315                 320 


Ser Cys Pro Ala Glu Leu Pro Asn Ile Lys Arg Glu Ile Ser Glu Thr 
                325                 330                 335     


Glu Ala Lys Ala Leu Leu Lys Glu Arg Gln Lys Lys Asp Asn His Asn 
            340                 345                 350         


Leu Ile Glu Arg Arg Arg Arg Phe Asn Ile Asn Asp Arg Ile Lys Glu 
        355                 360                 365             


Leu Gly Thr Leu Ile Pro Lys Ser Ser Asp Pro Glu Met Arg Trp Asn 
    370                 375                 380                 


Lys Gly Thr Ile Leu Lys Ala Ser Val Asp Tyr Ile Arg Lys Leu Gln 
385                 390                 395                 400 


Lys Glu Gln Gln Arg Ser Lys Asp Leu Glu Ser Arg Gln Arg Ser Leu 
                405                 410                 415     


Glu Gln Ala Asn Arg Ser Leu Gln Leu Arg Ile Gln Glu Leu Glu Leu 
            420                 425                 430         


Gln Ala Gln Ile His Gly Leu Pro Val Pro Pro Thr Pro Gly Leu Leu 
        435                 440                 445             


Ser Leu Ala Thr Thr Ser Ala Ser Asp Ser Leu Lys Pro Glu Gln Leu 
    450                 455                 460                 


Asp Ile Glu Glu Glu Gly Arg Pro Gly Ala Ala Thr Phe His Val Gly 
465                 470                 475                 480 


Gly Gly Pro Ala Gln Asn Ala Pro His Gln Gln Pro Pro Ala Pro Pro 
                485                 490                 495     


Ser Asp Ala Leu Leu Asp Leu His Phe Pro Ser Asp His Leu Gly Asp 
            500                 505                 510         


Leu Gly Asp Pro Phe His Leu Gly Leu Glu Asp Ile Leu Met Glu Glu 
        515                 520                 525             


Glu Glu Gly Val Val Gly Gly Leu Ser Gly Gly Ala Leu Ser Pro Leu 
    530                 535                 540                 


Arg Ala Ala Ser Asp Pro Leu Leu Ser Ser Val Ser Pro Ala Val Ser 
545                 550                 555                 560 


Lys Ala Ser Ser Arg Arg Ser Ser Phe Ser Met Glu Glu Glu Ser 
                565                 570                 575 


<210>  1261
<211>  175
<212>  PRT
<213>  Human

<400>  1261

Met Pro Lys Ser Cys Ala Ala Arg Gln Cys Cys Asn Arg Tyr Ser Ser 
1               5                   10                  15      


Arg Arg Lys Gln Leu Thr Phe His Arg Phe Pro Phe Ser Arg Pro Glu 
            20                  25                  30          


Leu Leu Lys Glu Trp Val Leu Asn Ile Gly Arg Gly Asn Phe Lys Pro 
        35                  40                  45              


Lys Gln His Thr Val Ile Cys Ser Glu His Phe Arg Pro Glu Cys Phe 
    50                  55                  60                  


Ser Ala Phe Gly Asn Arg Lys Asn Leu Lys His Asn Ala Val Pro Thr 
65                  70                  75                  80  


Val Phe Ala Phe Gln Asp Pro Thr Gln Gln Val Arg Glu Asn Thr Asp 
                85                  90                  95      


Pro Ala Ser Glu Arg Gly Asn Ala Ser Ser Ser Gln Lys Glu Lys Thr 
            100                 105                 110         


Ser Pro Cys Arg Ser Gln Val Leu Pro Glu Ala Gly Ala Gly Glu Asp 
        115                 120                 125             


Ser Pro Gly Arg Asn Met Asp Thr Ala Leu Glu Glu Leu Gln Leu Pro 
    130                 135                 140                 


Pro Asn Ala Glu Gly His Val Lys Gln Ala Met Leu Phe Asn Val Glu 
145                 150                 155                 160 


Asn Gly Thr Pro Ala Ser Arg Glu Ala Leu Trp Leu Ser Glu Glu 
                165                 170                 175 


<210>  1262
<211>  447
<212>  PRT
<213>  Human

<400>  1262

Met Asp Phe Leu Leu Gly Asn Pro Phe Ser Ser Pro Val Gly Gln Arg 
1               5                   10                  15      


Ile Glu Lys Ala Thr Asp Gly Ser Leu Gln Ser Glu Asp Trp Ala Leu 
            20                  25                  30          


Asn Met Glu Ile Cys Asp Ile Ile Asn Glu Thr Glu Glu Gly Pro Lys 
        35                  40                  45              


Asp Ala Leu Arg Ala Val Lys Lys Arg Ile Val Gly Asn Lys Asn Phe 
    50                  55                  60                  


His Glu Val Met Leu Ala Leu Thr Val Leu Glu Thr Cys Val Lys Asn 
65                  70                  75                  80  


Cys Gly His Arg Phe His Val Leu Val Ala Ser Gln Asp Phe Val Glu 
                85                  90                  95      


Ser Val Leu Val Arg Thr Ile Leu Pro Lys Asn Asn Pro Pro Thr Ile 
            100                 105                 110         


Val His Asp Lys Val Leu Asn Leu Ile Gln Thr Val Phe Asn Ser Glu 
        115                 120                 125             


Thr Gln Ser Gly Gln Asp Ser Val Gly Thr Asp Ser Ser Gln Gln Glu 
    130                 135                 140                 


Asp Ser Gly Gln His Ala Ala Pro Leu Pro Ala Pro Pro Ile Leu Ser 
145                 150                 155                 160 


Gly Asp Thr Pro Ile Ala Pro Thr Pro Glu Gln Ile Gly Lys Leu Arg 
                165                 170                 175     


Ser Glu Leu Glu Met Val Ser Gly Asn Val Arg Val Met Ser Glu Met 
            180                 185                 190         


Leu Thr Glu Leu Val Pro Thr Gln Ala Glu Pro Ala Asp Leu Glu Leu 
        195                 200                 205             


Leu Gln Glu Leu Asn Arg Thr Cys Arg Ala Met Gln Gln Arg Val Leu 
    210                 215                 220                 


Glu Leu Ile Pro Gln Ile Ala Asn Glu Gln Leu Thr Glu Glu Leu Leu 
225                 230                 235                 240 


Ile Val Asn Asp Asn Leu Asn Asn Val Phe Leu Arg His Glu Arg Phe 
                245                 250                 255     


Glu Arg Phe Arg Thr Gly Gln Thr Thr Lys Ala Pro Ser Glu Ala Glu 
            260                 265                 270         


Pro Ala Ala Asp Leu Ile Asp Met Gly Pro Asp Pro Ala Ala Thr Gly 
        275                 280                 285             


Asn Leu Ser Ser Gln Leu Ala Gly Met Asn Leu Gly Ser Ser Ser Val 
    290                 295                 300                 


Arg Ala Gly Leu Gln Ser Leu Glu Ala Ser Gly Arg Leu Glu Asp Glu 
305                 310                 315                 320 


Phe Asp Met Phe Ala Leu Thr Arg Gly Ser Ser Leu Ala Asp Gln Arg 
                325                 330                 335     


Lys Glu Val Lys Tyr Glu Ala Pro Gln Ala Thr Asp Gly Leu Ala Gly 
            340                 345                 350         


Ala Leu Asp Ala Arg Gln Gln Ser Thr Gly Ala Ile Pro Val Thr Gln 
        355                 360                 365             


Ala Cys Leu Met Glu Asp Ile Glu Gln Trp Leu Ser Thr Asp Val Gly 
    370                 375                 380                 


Asn Asp Ala Glu Glu Pro Lys Gly Val Thr Ser Glu Glu Phe Asp Lys 
385                 390                 395                 400 


Phe Leu Glu Glu Arg Ala Lys Ala Ala Asp Arg Leu Pro Asn Leu Ser 
                405                 410                 415     


Ser Pro Ser Ala Glu Gly Pro Pro Gly Pro Pro Ser Gly Pro Ala Pro 
            420                 425                 430         


Arg Lys Lys Thr Gln Glu Lys Asp Asp Asp Met Leu Phe Ala Leu 
        435                 440                 445         


<210>  1263
<211>  245
<212>  PRT
<213>  Human

<400>  1263

Met Ala Gly Ser Ser Ser Leu Glu Ala Val Arg Arg Lys Ile Arg Ser 
1               5                   10                  15      


Leu Gln Glu Gln Ala Asp Ala Ala Glu Glu Arg Ala Gly Thr Leu Gln 
            20                  25                  30          


Arg Glu Leu Asp His Glu Arg Lys Leu Arg Glu Thr Ala Glu Ala Asp 
        35                  40                  45              


Val Ala Ser Leu Asn Arg Arg Ile Gln Leu Val Glu Glu Glu Leu Asp 
    50                  55                  60                  


Arg Ala Gln Glu Arg Leu Ala Thr Ala Leu Gln Lys Leu Glu Glu Ala 
65                  70                  75                  80  


Glu Lys Ala Ala Asp Glu Ser Glu Arg Gly Met Lys Val Ile Glu Ser 
                85                  90                  95      


Arg Ala Gln Lys Asp Glu Glu Lys Met Glu Ile Gln Glu Ile Gln Leu 
            100                 105                 110         


Lys Glu Ala Lys His Ile Ala Glu Asp Ala Asp Arg Lys Tyr Glu Glu 
        115                 120                 125             


Val Ala Arg Lys Leu Val Ile Ile Glu Ser Asp Leu Glu Arg Ala Glu 
    130                 135                 140                 


Glu Arg Ala Glu Leu Ser Glu Gly Lys Cys Ala Glu Leu Glu Glu Glu 
145                 150                 155                 160 


Leu Lys Thr Val Thr Asn Asn Leu Lys Ser Leu Glu Ala Gln Ala Glu 
                165                 170                 175     


Lys Tyr Ser Gln Lys Glu Asp Arg Tyr Glu Glu Glu Ile Lys Val Leu 
            180                 185                 190         


Ser Asp Lys Leu Lys Glu Ala Glu Thr Arg Ala Glu Phe Ala Glu Arg 
        195                 200                 205             


Ser Val Thr Lys Leu Glu Lys Ser Ile Asp Asp Leu Glu Asp Gln Leu 
    210                 215                 220                 


Tyr Gln Gln Leu Glu Gln Asn Arg Arg Leu Thr Asn Glu Leu Lys Leu 
225                 230                 235                 240 


Ala Leu Asn Glu Asp 
                245 


<210>  1264
<211>  287
<212>  PRT
<213>  Human

<400>  1264

Met Ala Ala Ser Leu Trp Met Gly Asp Leu Glu Pro Tyr Met Asp Glu 
1               5                   10                  15      


Asn Phe Ile Ser Arg Ala Phe Ala Thr Met Gly Glu Thr Val Met Ser 
            20                  25                  30          


Val Lys Ile Ile Arg Asn Arg Leu Thr Gly Ile Pro Ala Gly Tyr Cys 
        35                  40                  45              


Phe Val Glu Phe Ala Asp Leu Ala Thr Ala Glu Lys Cys Leu His Lys 
    50                  55                  60                  


Ile Asn Gly Lys Pro Leu Pro Gly Ala Thr Pro Ala Lys Arg Phe Lys 
65                  70                  75                  80  


Leu Asn Tyr Ala Thr Tyr Gly Lys Gln Pro Asp Asn Ser Pro Glu Tyr 
                85                  90                  95      


Ser Leu Phe Val Gly Asp Leu Thr Pro Asp Val Asp Asp Gly Met Leu 
            100                 105                 110         


Tyr Glu Phe Phe Val Lys Val Tyr Pro Ser Cys Arg Gly Gly Lys Val 
        115                 120                 125             


Val Leu Asp Gln Thr Gly Val Ser Lys Gly Tyr Gly Phe Val Lys Phe 
    130                 135                 140                 


Thr Asp Glu Leu Glu Gln Lys Arg Ala Leu Thr Glu Cys Gln Gly Ala 
145                 150                 155                 160 


Val Gly Leu Gly Ser Lys Pro Val Arg Leu Ser Val Ala Ile Pro Lys 
                165                 170                 175     


Ala Ser Arg Val Lys Pro Val Glu Tyr Ser Gln Met Tyr Ser Tyr Ser 
            180                 185                 190         


Tyr Asn Gln Tyr Tyr Gln Gln Tyr Gln Asn Tyr Tyr Ala Gln Trp Gly 
        195                 200                 205             


Tyr Asp Gln Asn Thr Gly Ser Tyr Ser Tyr Ser Tyr Pro Gln Tyr Gly 
    210                 215                 220                 


Tyr Thr Gln Ser Thr Met Gln Thr Tyr Glu Glu Val Gly Asp Asp Ala 
225                 230                 235                 240 


Leu Glu Asp Pro Met Pro Gln Leu Asp Val Thr Glu Ala Asn Lys Glu 
                245                 250                 255     


Phe Met Glu Gln Ser Glu Glu Leu Tyr Asp Ala Leu Met Asp Cys His 
            260                 265                 270         


Trp Gln Pro Leu Asp Thr Val Ser Ser Glu Ile Pro Ala Met Met 
        275                 280                 285         


<210>  1265
<211>  772
<212>  PRT
<213>  Human

<400>  1265

Met Asn Arg Leu Arg Asn Ala Lys Ile Tyr Val Glu Arg Ala Val Lys 
1               5                   10                  15      


Gln Lys Lys Ile Phe Thr Ile Gln Gly Cys Tyr Pro Val Ile Arg Cys 
            20                  25                  30          


Leu Leu Arg Arg Arg Gly Trp Val Glu Lys Lys Met Val His Arg Ser 
        35                  40                  45              


Gly Pro Thr Leu Leu Pro Pro Gln Lys Asp Leu Asp Ser Ser Ala Met 
    50                  55                  60                  


Gly Asp Ser Asp Thr Thr Glu Asp Glu Asp Glu Asp Glu Asp Glu Glu 
65                  70                  75                  80  


Phe Gln Pro Ser Gln Leu Phe Asp Phe Asp Asp Leu Leu Lys Phe Asp 
                85                  90                  95      


Asp Leu Asp Gly Thr His Ala Leu Met Val Gly Leu Cys Leu Asn Leu 
            100                 105                 110         


Arg Asn Leu Pro Trp Phe Asp Glu Val Asp Ala Asn Ser Phe Phe Pro 
        115                 120                 125             


Arg Cys Tyr Cys Leu Gly Ala Glu Asp Asp Lys Lys Ala Phe Ile Glu 
    130                 135                 140                 


Asp Phe Trp Leu Thr Ala Ala Arg Asn Val Leu Lys Leu Val Val Lys 
145                 150                 155                 160 


Ser Glu Trp Lys Ser Tyr Pro Ile Gln Ala Val Glu Glu Glu Ala Ser 
                165                 170                 175     


Gly Asp Lys Gln Pro Lys Lys Gln Glu Lys Asn Pro Val Leu Val Ser 
            180                 185                 190         


Pro Glu Phe Val Asp Glu Ala Leu Cys Ala Cys Glu Glu Tyr Leu Ser 
        195                 200                 205             


Asn Leu Ala His Met Asp Ile Asp Lys Asp Leu Glu Ala Pro Leu Tyr 
    210                 215                 220                 


Leu Thr Pro Glu Gly Trp Ser Leu Phe Leu Gln Arg Tyr Tyr Gln Val 
225                 230                 235                 240 


Val His Glu Gly Ala Glu Leu Arg His Leu Asp Thr Gln Val Gln Arg 
                245                 250                 255     


Cys Glu Asp Ile Leu Gln Gln Leu Gln Ala Val Val Pro Gln Ile Asp 
            260                 265                 270         


Met Glu Gly Asp Arg Asn Ile Trp Ile Val Lys Pro Gly Ala Lys Ser 
        275                 280                 285             


Arg Gly Arg Gly Ile Met Cys Met Asp His Leu Glu Glu Met Leu Lys 
    290                 295                 300                 


Leu Val Asn Gly Asn Pro Val Val Met Lys Asp Gly Lys Trp Val Val 
305                 310                 315                 320 


Gln Lys Tyr Ile Glu Arg Pro Leu Leu Ile Phe Gly Thr Lys Phe Asp 
                325                 330                 335     


Leu Arg Gln Trp Phe Leu Val Thr Asp Trp Asn Pro Leu Thr Val Trp 
            340                 345                 350         


Phe Tyr Arg Asp Ser Tyr Ile Arg Phe Ser Thr Gln Pro Phe Ser Leu 
        355                 360                 365             


Lys Asn Leu Asp Asn Ser Val His Leu Cys Asn Asn Ser Ile Gln Lys 
    370                 375                 380                 


His Leu Glu Asn Ser Cys His Arg His Pro Leu Leu Pro Pro Asp Asn 
385                 390                 395                 400 


Met Trp Ser Ser Gln Arg Phe Gln Ala His Leu Gln Glu Met Gly Ala 
                405                 410                 415     


Pro Asn Ala Trp Ser Thr Ile Ile Val Pro Gly Met Lys Asp Ala Val 
            420                 425                 430         


Ile His Ala Leu Gln Thr Ser Gln Asp Thr Val Gln Cys Arg Lys Ala 
        435                 440                 445             


Ser Phe Glu Leu Tyr Gly Ala Asp Phe Val Phe Gly Glu Asp Phe Gln 
    450                 455                 460                 


Pro Trp Leu Ile Glu Ile Asn Ala Ser Pro Thr Met Ala Pro Ser Thr 
465                 470                 475                 480 


Ala Val Thr Ala Arg Leu Cys Ala Gly Val Gln Ala Asp Thr Leu Arg 
                485                 490                 495     


Val Val Ile Asp Arg Met Leu Asp Arg Asn Cys Asp Thr Gly Ala Phe 
            500                 505                 510         


Glu Leu Ile Tyr Lys Gln Pro Ala Val Glu Val Pro Gln Tyr Val Gly 
        515                 520                 525             


Ile Arg Leu Leu Val Glu Gly Phe Thr Ile Lys Lys Pro Met Ala Met 
    530                 535                 540                 


Cys His Arg Arg Met Gly Val Arg Pro Ala Val Pro Leu Leu Thr Gln 
545                 550                 555                 560 


Arg Gly Ser Gly Glu Ala Arg His His Phe Pro Ser Leu His Thr Lys 
                565                 570                 575     


Ala Gln Leu Pro Ser Pro His Val Leu Arg His Gln Gly Gln Val Leu 
            580                 585                 590         


Arg Arg Gln His Ser Lys Leu Val Gly Thr Lys Ala Leu Ser Thr Thr 
        595                 600                 605             


Gly Lys Ala Leu Arg Thr Leu Pro Thr Ala Lys Val Phe Ile Ser Leu 
    610                 615                 620                 


Pro Pro Asn Leu Asp Phe Lys Val Ala Pro Ser Ile Leu Lys Pro Arg 
625                 630                 635                 640 


Lys Ala Pro Ala Leu Leu Cys Leu Arg Gly Pro Gln Leu Glu Val Pro 
                645                 650                 655     


Cys Cys Leu Cys Pro Leu Lys Ser Glu Gln Phe Leu Ala Pro Val Gly 
            660                 665                 670         


Arg Ser Arg Pro Lys Ala Asn Ser Arg Pro Asp Cys Asp Lys Pro Arg 
        675                 680                 685             


Ala Glu Ala Cys Pro Met Lys Arg Leu Ser Pro Leu Lys Pro Leu Pro 
    690                 695                 700                 


Leu Val Gly Thr Phe Gln Arg Arg Arg Gly Leu Gly Asp Met Lys Leu 
705                 710                 715                 720 


Gly Lys Pro Leu Leu Arg Phe Pro Thr Ala Leu Val Leu Asp Pro Thr 
                725                 730                 735     


Pro Asn Lys Lys Lys Gln Val Lys Tyr Leu Gly Leu Asp Ser Ile Ala 
            740                 745                 750         


Val Gly Gly Ser Arg Val Asp Gly Ala Arg Pro Cys Thr Pro Gly Ser 
        755                 760                 765             


Thr Ala Arg Ala 
    770         


<210>  1266
<211>  261
<212>  PRT
<213>  Human

<400>  1266

Met Ala Gly Asp Ser Glu Gln Thr Leu Gln Asn His Gln Gln Pro Asn 
1               5                   10                  15      


Gly Gly Glu Pro Phe Leu Ile Gly Val Ser Gly Gly Thr Ala Ser Gly 
            20                  25                  30          


Lys Ser Ser Val Cys Ala Lys Ile Val Gln Leu Leu Gly Gln Asn Glu 
        35                  40                  45              


Val Asp Tyr Arg Gln Lys Gln Val Val Ile Leu Ser Gln Asp Ser Phe 
    50                  55                  60                  


Tyr Arg Val Leu Thr Ser Glu Gln Lys Ala Lys Ala Leu Lys Gly Gln 
65                  70                  75                  80  


Phe Asn Phe Asp His Pro Asp Ala Phe Asp Asn Glu Leu Ile Leu Lys 
                85                  90                  95      


Thr Leu Lys Glu Ile Thr Glu Gly Lys Thr Val Gln Ile Pro Val Tyr 
            100                 105                 110         


Asp Phe Val Ser His Ser Arg Lys Glu Glu Thr Val Thr Val Tyr Pro 
        115                 120                 125             


Ala Asp Val Val Leu Phe Glu Gly Ile Leu Ala Phe Tyr Ser Gln Glu 
    130                 135                 140                 


Val Arg Asp Leu Phe Gln Met Lys Leu Phe Val Asp Thr Asp Ala Asp 
145                 150                 155                 160 


Thr Arg Leu Ser Arg Arg Val Leu Arg Asp Ile Ser Glu Arg Gly Arg 
                165                 170                 175     


Asp Leu Glu Gln Ile Leu Ser Gln Tyr Ile Thr Phe Val Lys Pro Ala 
            180                 185                 190         


Phe Glu Glu Phe Cys Leu Pro Thr Lys Lys Tyr Ala Asp Val Ile Ile 
        195                 200                 205             


Pro Arg Gly Ala Asp Asn Leu Val Ala Ile Asn Leu Ile Val Gln His 
    210                 215                 220                 


Ile Gln Asp Ile Leu Asn Gly Gly Pro Ser Lys Arg Gln Thr Asn Gly 
225                 230                 235                 240 


Cys Leu Asn Gly Tyr Thr Pro Ser Arg Lys Arg Gln Ala Ser Glu Ser 
                245                 250                 255     


Ser Ser Arg Pro His 
            260     


<210>  1267
<211>  322
<212>  PRT
<213>  Human

<400>  1267

Lys Ser Arg Ile Ser Lys Lys Pro Gln Val Pro Lys Lys Pro Arg Glu 
1               5                   10                  15      


Trp Lys Asn Pro Glu Ser Gln Arg Gly Leu Ser Gly Ala Gln Asp Pro 
            20                  25                  30          


Phe Pro Gly Pro Ala Pro Val Pro Val Glu Val Val Gln Lys Phe Cys 
        35                  40                  45              


Arg Ile Asp Lys Ser Arg Lys Leu Pro His Ser Lys Ala Lys Thr Arg 
    50                  55                  60                  


Ser Arg Leu Glu Val Ala Glu Ala Glu Glu Glu Glu Thr Ser Ile Lys 
65                  70                  75                  80  


Ala Ala Arg Ser Glu Leu Leu Leu Ala Glu Glu Pro Gly Phe Leu Glu 
                85                  90                  95      


Gly Glu Asp Gly Glu Asp Thr Ala Lys Ile Cys Gln Ala Asp Ile Val 
            100                 105                 110         


Glu Ala Val Asp Ile Ala Ser Ala Ala Lys Phe Gly Pro Tyr Arg Leu 
        115                 120                 125             


Asn Tyr Ser Arg Thr Gly Arg His Leu Ala Phe Gly Gly Arg Arg Gly 
    130                 135                 140                 


His Val Ala Ala Leu Asp Trp Val Thr Lys Lys Leu Met Cys Glu Ile 
145                 150                 155                 160 


Asn Val Met Glu Ala Val Arg Asp Ile Arg Phe Leu His Ser Glu Ala 
                165                 170                 175     


Leu Leu Ala Val Ala Gln Asn Arg Trp Leu His Ile Tyr Asp Asn Gln 
            180                 185                 190         


Gly Ile Glu Leu His Cys Ile Arg Arg Cys Asp Arg Val Thr Arg Leu 
        195                 200                 205             


Glu Phe Leu Pro Phe His Phe Leu Leu Ala Thr Ala Ser Glu Thr Gly 
    210                 215                 220                 


Phe Leu Thr Tyr Leu Asp Val Ser Val Gly Lys Ile Val Ala Ala Leu 
225                 230                 235                 240 


Asn Ala Arg Ala Gly Arg Leu Asp Val Met Ser Gln Asn Pro Tyr Asn 
                245                 250                 255     


Ala Val Ile His Leu Gly His Ser Asn Gly Thr Ala Ser Leu Trp Ser 
            260                 265                 270         


Pro Ala Met Lys Glu Pro Leu Ala Lys Ile Leu Cys His Arg Gly Gly 
        275                 280                 285             


Val Arg Ala Val Ala Val Asp Ser Thr Gly Thr Tyr Met Ala Thr Ser 
    290                 295                 300                 


Gly Leu Asp His Gln Leu Lys Ile Phe Asp Leu Arg Gly Thr Tyr Gln 
305                 310                 315                 320 


Pro Leu 
        


<210>  1268
<211>  654
<212>  PRT
<213>  Human

<400>  1268

Met Glu Arg Ser Gly Pro Ser Glu Val Thr Gly Ser Asp Ala Ser Gly 
1               5                   10                  15      


Pro Asp Pro Gln Leu Ala Val Thr Met Gly Phe Thr Gly Phe Gly Lys 
            20                  25                  30          


Lys Ala Arg Thr Phe Asp Leu Glu Ala Met Phe Glu Gln Thr Arg Arg 
        35                  40                  45              


Thr Ala Val Glu Arg Ser Arg Lys Thr Leu Glu Ala Arg Glu Lys Glu 
    50                  55                  60                  


Glu Glu Met Asn Arg Glu Lys Glu Leu Arg Arg Gln Asn Glu Asp Ile 
65                  70                  75                  80  


Glu Pro Thr Ser Ser Arg Ser Asn Val Val Arg Asp Cys Ser Lys Ser 
                85                  90                  95      


Ser Ser Arg Asp Thr Ser Ser Ser Glu Ser Glu Gln Ser Ser Asp Ser 
            100                 105                 110         


Ser Asp Asp Glu Leu Ile Gly Pro Pro Leu Pro Pro Lys Met Val Gly 
        115                 120                 125             


Lys Pro Val Asn Phe Met Glu Glu Asp Ile Leu Gly Pro Leu Pro Pro 
    130                 135                 140                 


Pro Leu Asn Glu Glu Glu Glu Glu Ala Glu Glu Glu Glu Glu Glu Glu 
145                 150                 155                 160 


Glu Glu Glu Glu Asn Pro Val His Lys Ile Pro Asp Ser His Glu Ile 
                165                 170                 175     


Thr Leu Lys His Gly Thr Lys Thr Val Ser Ala Leu Gly Leu Asp Pro 
            180                 185                 190         


Ser Gly Ala Arg Leu Val Thr Gly Gly Tyr Asp Tyr Asp Val Lys Phe 
        195                 200                 205             


Trp Asp Phe Ala Gly Met Asp Ala Ser Phe Lys Ala Phe Arg Ser Leu 
    210                 215                 220                 


Gln Pro Cys Glu Cys His Gln Ile Lys Ser Leu Gln Tyr Ser Asn Thr 
225                 230                 235                 240 


Gly Asp Met Ile Leu Val Val Ser Gly Ser Ser Gln Ala Lys Val Ile 
                245                 250                 255     


Asp Arg Asp Gly Phe Glu Val Met Glu Cys Ile Lys Gly Asp Gln Tyr 
            260                 265                 270         


Ile Val Asp Met Ala Asn Thr Lys Gly His Thr Ala Met Leu His Thr 
        275                 280                 285             


Gly Ser Trp His Pro Lys Ile Lys Gly Glu Phe Met Thr Cys Ser Asn 
    290                 295                 300                 


Asp Ala Thr Val Arg Thr Trp Glu Val Glu Asn Pro Lys Lys Gln Lys 
305                 310                 315                 320 


Ser Val Phe Lys Pro Arg Thr Met Gln Gly Lys Lys Val Ile Pro Thr 
                325                 330                 335     


Thr Cys Thr Tyr Ser Arg Asp Gly Asn Leu Ile Ala Ala Ala Cys Gln 
            340                 345                 350         


Asn Gly Ser Ile Gln Ile Trp Asp Arg Asn Leu Thr Val His Pro Lys 
        355                 360                 365             


Phe His Tyr Lys Gln Ala His Asp Ser Gly Thr Asp Thr Ser Cys Val 
    370                 375                 380                 


Thr Phe Ser Tyr Asp Gly Asn Val Leu Ala Ser Arg Gly Gly Asp Asp 
385                 390                 395                 400 


Ser Leu Lys Leu Trp Asp Ile Arg Gln Phe Asn Lys Pro Leu Phe Ser 
                405                 410                 415     


Ala Ser Gly Leu Pro Thr Met Phe Pro Met Thr Asp Cys Cys Phe Ser 
            420                 425                 430         


Pro Asp Asp Lys Leu Ile Val Thr Gly Thr Ser Ile Gln Arg Gly Cys 
        435                 440                 445             


Gly Ser Gly Lys Leu Val Phe Phe Glu Arg Arg Thr Phe Gln Arg Val 
    450                 455                 460                 


Tyr Glu Ile Asp Ile Thr Asp Ala Ser Val Val Arg Cys Leu Trp His 
465                 470                 475                 480 


Pro Lys Leu Asn Gln Ile Met Val Gly Thr Gly Asn Gly Leu Ala Lys 
                485                 490                 495     


Val Tyr Tyr Asp Pro Asn Lys Ser Gln Arg Gly Ala Lys Leu Cys Val 
            500                 505                 510         


Val Lys Thr Gln Arg Lys Ala Lys Gln Ala Glu Thr Leu Thr Gln Asp 
        515                 520                 525             


Tyr Ile Ile Thr Pro His Ala Leu Pro Met Phe Arg Glu Pro Arg Gln 
    530                 535                 540                 


Arg Ser Thr Arg Lys Gln Leu Glu Lys Asp Arg Leu Asp Pro Leu Lys 
545                 550                 555                 560 


Ser His Lys Pro Glu Pro Pro Val Ala Gly Pro Gly Arg Gly Gly Arg 
                565                 570                 575     


Val Gly Thr His Gly Gly Thr Leu Ser Ser Tyr Ile Val Lys Asn Ile 
            580                 585                 590         


Ala Leu Asp Lys Thr Asp Asp Ser Asn Pro Arg Glu Ala Ile Leu Arg 
        595                 600                 605             


His Ala Lys Ala Ala Glu Asp Ser Pro Tyr Trp Val Ser Pro Ala Tyr 
    610                 615                 620                 


Ser Lys Thr Gln Pro Lys Thr Met Phe Ala Gln Val Glu Ser Asp Asp 
625                 630                 635                 640 


Glu Glu Ala Lys Asn Glu Pro Glu Trp Lys Lys Arg Lys Ile 
                645                 650                 


<210>  1269
<211>  676
<212>  PRT
<213>  Human

<400>  1269

Met Ala Lys Val Asn Ile Thr Arg Asp Leu Ile Arg Arg Gln Ile Lys 
1               5                   10                  15      


Glu Arg Gly Ala Leu Ser Phe Glu Arg Arg Tyr His Val Thr Asp Pro 
            20                  25                  30          


Phe Ile Arg Arg Leu Gly Leu Glu Ala Glu Leu Gln Gly His Ser Gly 
        35                  40                  45              


Cys Val Asn Cys Leu Glu Trp Asn Glu Lys Gly Asp Leu Leu Ala Ser 
    50                  55                  60                  


Gly Ser Asp Asp Gln His Thr Ile Val Trp Asp Pro Leu His His Lys 
65                  70                  75                  80  


Lys Leu Leu Ser Met His Thr Gly His Thr Ala Asn Ile Phe Ser Val 
                85                  90                  95      


Lys Phe Leu Pro His Ala Gly Asp Arg Ile Leu Ile Thr Gly Ala Ala 
            100                 105                 110         


Asp Ser Lys Val His Val His Asp Leu Thr Val Lys Glu Thr Ile His 
        115                 120                 125             


Met Phe Gly Asp His Thr Asn Arg Val Lys Arg Ile Ala Thr Ala Pro 
    130                 135                 140                 


Met Trp Pro Asn Thr Phe Trp Ser Ala Ala Glu Asp Gly Leu Ile Arg 
145                 150                 155                 160 


Gln Tyr Asp Leu Arg Glu Asn Ser Lys His Ser Glu Val Leu Ile Asp 
                165                 170                 175     


Leu Thr Glu Tyr Cys Gly Gln Leu Val Glu Ala Lys Cys Leu Thr Val 
            180                 185                 190         


Asn Pro Gln Asp Asn Asn Cys Leu Ala Val Gly Ala Ser Gly Pro Phe 
        195                 200                 205             


Val Arg Leu Tyr Asp Ile Arg Met Ile His Asn His Arg Lys Ser Met 
    210                 215                 220                 


Lys Gln Ser Pro Ser Ala Gly Val His Thr Phe Cys Asp Arg Gln Lys 
225                 230                 235                 240 


Pro Leu Pro Asp Gly Ala Ala Gln Tyr Tyr Val Ala Gly His Leu Pro 
                245                 250                 255     


Val Lys Leu Pro Asp Tyr Asn Asn Arg Leu Arg Val Leu Val Ala Thr 
            260                 265                 270         


Tyr Val Thr Phe Ser Pro Asn Gly Thr Glu Leu Leu Val Asn Met Gly 
        275                 280                 285             


Gly Glu Gln Val Tyr Leu Phe Asp Leu Thr Tyr Lys Gln Arg Pro Tyr 
    290                 295                 300                 


Thr Phe Leu Leu Pro Arg Lys Cys His Ser Ser Gly Val Gln Asn Gly 
305                 310                 315                 320 


Lys Met Ser Thr Asn Gly Val Ser Asn Gly Val Ser Asn Gly Leu His 
                325                 330                 335     


Leu His Ser Asn Gly Phe Arg Leu Pro Glu Ser Arg Gly His Val Ser 
            340                 345                 350         


Pro Gln Val Glu Leu Pro Pro Tyr Leu Glu Arg Val Lys Gln Gln Ala 
        355                 360                 365             


Asn Glu Ala Phe Ala Cys Gln Gln Trp Thr Gln Ala Ile Gln Leu Tyr 
    370                 375                 380                 


Ser Lys Ala Val Gln Arg Ala Pro His Asn Ala Met Leu Tyr Gly Asn 
385                 390                 395                 400 


Arg Ala Ala Ala Tyr Met Lys Arg Lys Trp Asp Gly Asp His Tyr Asp 
                405                 410                 415     


Ala Leu Arg Asp Cys Leu Lys Ala Ile Ser Leu Asn Pro Cys His Leu 
            420                 425                 430         


Lys Ala His Phe Arg Leu Ala Arg Cys Leu Phe Glu Leu Lys Tyr Val 
        435                 440                 445             


Ala Glu Ala Leu Glu Cys Leu Asp Asp Phe Lys Gly Lys Phe Pro Glu 
    450                 455                 460                 


Gln Ala His Ser Ser Ala Cys Asp Ala Leu Gly Arg Asp Ile Thr Ala 
465                 470                 475                 480 


Ala Leu Phe Ser Lys Asn Asp Gly Glu Glu Lys Lys Gly Pro Gly Gly 
                485                 490                 495     


Gly Ala Pro Val Arg Leu Arg Ser Thr Ser Arg Lys Asp Ser Ile Ser 
            500                 505                 510         


Glu Asp Glu Met Val Leu Arg Glu Arg Ser Tyr Asp Tyr Gln Phe Arg 
        515                 520                 525             


Tyr Cys Gly His Cys Asn Thr Thr Thr Asp Ile Lys Glu Ala Asn Phe 
    530                 535                 540                 


Phe Gly Ser Asn Ala Gln Tyr Ile Val Ser Gly Ser Asp Asp Gly Ser 
545                 550                 555                 560 


Phe Phe Ile Trp Glu Lys Glu Thr Thr Asn Leu Val Arg Val Leu Gln 
                565                 570                 575     


Gly Asp Glu Ser Ile Val Asn Cys Leu Gln Pro His Pro Ser Tyr Cys 
            580                 585                 590         


Phe Leu Ala Thr Ser Gly Ile Asp Pro Val Val Arg Leu Trp Asn Pro 
        595                 600                 605             


Arg Pro Glu Ser Glu Asp Leu Thr Gly Arg Val Val Glu Asp Met Glu 
    610                 615                 620                 


Gly Ala Ser Gln Ala Asn Gln Arg Arg Met Asn Ala Asp Pro Leu Glu 
625                 630                 635                 640 


Val Met Leu Leu Asn Met Gly Tyr Arg Ile Thr Gly Leu Ser Ser Gly 
                645                 650                 655     


Gly Ala Gly Ala Ser Asp Asp Glu Asp Ser Ser Glu Gly Gln Val Gln 
            660                 665                 670         


Cys Arg Pro Ser 
        675     


<210>  1270
<211>  496
<212>  PRT
<213>  Human

<400>  1270

Met Glu Leu Pro Ser Pro Glu Ser Glu Glu Val His Glu Pro Arg Leu 
1               5                   10                  15      


Gly Glu Leu Leu Gly Asn Pro Glu Gly Gln Ser Leu Gly Ser Ser Pro 
            20                  25                  30          


Ser Gln Asp Arg Gly Cys Lys Gln Val Thr Val Thr His Trp Lys Ile 
        35                  40                  45              


Gln Thr Gly Glu Thr Ala Gln Val Cys Thr Lys Ser Gly Arg Asn His 
    50                  55                  60                  


Ile Leu Asn Ser Asp Leu Leu Leu Leu Gln Arg Glu Leu Ile Glu Gly 
65                  70                  75                  80  


Glu Ala Asn Pro Cys Asp Ile Cys Gly Lys Thr Phe Thr Phe Asn Ser 
                85                  90                  95      


Asp Leu Val Arg His Arg Ile Ser His Ala Gly Glu Lys Pro Tyr Thr 
            100                 105                 110         


Cys Asp Gln Cys Gly Lys Gly Phe Gly Gln Ser Ser His Leu Met Glu 
        115                 120                 125             


His Gln Arg Ile His Thr Gly Glu Arg Leu Tyr Val Cys Asn Val Cys 
    130                 135                 140                 


Gly Lys Asp Phe Ile His Tyr Ser Gly Leu Ile Glu His Gln Arg Val 
145                 150                 155                 160 


His Ser Gly Glu Lys Pro Phe Lys Cys Ala Gln Cys Gly Lys Ala Phe 
                165                 170                 175     


Cys His Ser Ser Asp Leu Ile Arg His Gln Arg Val His Thr Arg Glu 
            180                 185                 190         


Arg Pro Phe Glu Cys Lys Glu Cys Gly Lys Gly Phe Ser Gln Ser Ser 
        195                 200                 205             


Leu Leu Ile Arg His Gln Arg Ile His Thr Gly Glu Arg Pro Tyr Glu 
    210                 215                 220                 


Cys Asn Glu Cys Gly Lys Ser Phe Ile Arg Ser Ser Ser Leu Ile Arg 
225                 230                 235                 240 


His Tyr Gln Ile His Thr Glu Val Lys Gln Tyr Glu Cys Lys Glu Cys 
                245                 250                 255     


Gly Lys Ala Phe Arg His Arg Ser Asp Leu Ile Glu His Gln Arg Ile 
            260                 265                 270         


His Thr Gly Glu Arg Pro Phe Glu Cys Asn Glu Cys Gly Lys Ala Phe 
        275                 280                 285             


Ile Arg Ser Ser Lys Leu Ile Gln His Gln Arg Ile His Thr Gly Glu 
    290                 295                 300                 


Arg Pro Tyr Val Cys Asn Glu Cys Gly Lys Arg Phe Ser Gln Thr Ser 
305                 310                 315                 320 


Asn Phe Thr Gln His Gln Arg Ile His Thr Gly Glu Lys Leu Tyr Glu 
                325                 330                 335     


Cys Asn Glu Cys Gly Lys Ala Phe Phe Leu Ser Ser Tyr Leu Ile Arg 
            340                 345                 350         


His Gln Lys Ile His Thr Gly Glu Arg Val Tyr Glu Cys Lys Glu Cys 
        355                 360                 365             


Gly Lys Ala Phe Leu Gln Lys Ala His Leu Thr Glu His Gln Lys Ile 
    370                 375                 380                 


His Ser Gly Asp Arg Pro Phe Glu Cys Lys Asp Cys Gly Lys Ala Phe 
385                 390                 395                 400 


Ile Gln Ser Ser Lys Leu Leu Leu His Gln Ile Ile His Thr Gly Glu 
                405                 410                 415     


Lys Pro Tyr Val Cys Ser Tyr Cys Gly Lys Gly Phe Ile Gln Arg Ser 
            420                 425                 430         


Asn Phe Leu Gln His Gln Lys Ile His Thr Glu Glu Lys Leu Tyr Glu 
        435                 440                 445             


Cys Ser Gln Tyr Gly Arg Asp Phe Asn Ser Thr Thr Asn Val Lys Asn 
    450                 455                 460                 


Asn Gln Arg Val His Gln Glu Gly Leu Ser Leu Ser Lys Ala Pro Ile 
465                 470                 475                 480 


His Leu Gly Glu Arg Ser Val Asp Lys Gly Glu His Thr Gly Asn Leu 
                485                 490                 495     


<210>  1271
<211>  858
<212>  PRT
<213>  Human

<400>  1271

Met Asp Leu Pro Ala Leu Leu Pro Ala Pro Thr Ala Arg Gly Gly Gln 
1               5                   10                  15      


His Gly Gly Gly Pro Gly Pro Leu Arg Arg Ala Pro Ala Pro Leu Gly 
            20                  25                  30          


Ala Ser Pro Ala Arg Arg Arg Leu Leu Leu Val Arg Gly Pro Glu Asp 
        35                  40                  45              


Gly Gly Pro Gly Ala Arg Pro Gly Glu Ala Ser Gly Pro Ser Pro Pro 
    50                  55                  60                  


Pro Ala Glu Asp Asp Ser Asp Gly Asp Ser Phe Leu Val Leu Leu Glu 
65                  70                  75                  80  


Val Pro His Gly Gly Ala Ala Ala Glu Ala Ala Gly Ser Gln Glu Ala 
                85                  90                  95      


Glu Pro Gly Ser Arg Val Asn Leu Ala Ser Arg Pro Glu Gln Gly Pro 
            100                 105                 110         


Ser Gly Pro Ala Ala Pro Pro Gly Pro Gly Val Ala Pro Ala Gly Ala 
        115                 120                 125             


Val Thr Ile Ser Ser Gln Asp Leu Leu Val Arg Leu Asp Arg Gly Val 
    130                 135                 140                 


Leu Ala Leu Ser Ala Pro Pro Gly Pro Ala Thr Ala Gly Ala Ala Ala 
145                 150                 155                 160 


Pro Arg Arg Ala Pro Gln Ala Ser Gly Pro Ser Thr Pro Gly Tyr Arg 
                165                 170                 175     


Cys Pro Glu Pro Gln Cys Ala Leu Ala Phe Ala Lys Lys His Gln Leu 
            180                 185                 190         


Lys Val His Leu Leu Thr His Gly Gly Gly Gln Gly Arg Arg Pro Phe 
        195                 200                 205             


Lys Cys Pro Leu Glu Gly Cys Gly Trp Ala Phe Thr Thr Ser Tyr Lys 
    210                 215                 220                 


Leu Lys Arg His Leu Gln Ser His Asp Lys Leu Arg Pro Phe Gly Cys 
225                 230                 235                 240 


Pro Val Gly Gly Cys Gly Lys Lys Phe Thr Thr Val Tyr Asn Leu Lys 
                245                 250                 255     


Ala His Met Lys Gly His Glu Gln Glu Ser Leu Phe Lys Cys Glu Val 
            260                 265                 270         


Cys Ala Glu Arg Phe Pro Thr His Ala Lys Leu Ser Ser His Gln Arg 
        275                 280                 285             


Ser His Phe Glu Pro Glu Arg Pro Tyr Lys Cys Asp Phe Pro Gly Cys 
    290                 295                 300                 


Glu Lys Thr Phe Ile Thr Val Ser Ala Leu Phe Ser His Asn Arg Ala 
305                 310                 315                 320 


His Phe Arg Glu Gln Glu Leu Phe Ser Cys Ser Phe Pro Gly Cys Ser 
                325                 330                 335     


Lys Gln Tyr Asp Lys Ala Cys Arg Leu Lys Ile His Leu Arg Ser His 
            340                 345                 350         


Thr Gly Glu Arg Pro Phe Ile Cys Asp Ser Asp Ser Cys Gly Trp Thr 
        355                 360                 365             


Phe Thr Ser Met Ser Lys Leu Leu Arg His Arg Arg Lys His Asp Asp 
    370                 375                 380                 


Asp Arg Arg Phe Thr Cys Pro Val Glu Gly Cys Gly Lys Ser Phe Thr 
385                 390                 395                 400 


Arg Ala Glu His Leu Lys Gly His Ser Ile Thr His Leu Gly Thr Lys 
                405                 410                 415     


Pro Phe Glu Cys Pro Val Glu Gly Cys Cys Ala Arg Phe Ser Ala Arg 
            420                 425                 430         


Ser Ser Leu Tyr Ile His Ser Lys Lys His Val Gln Asp Val Gly Ala 
        435                 440                 445             


Pro Lys Ser Arg Cys Pro Val Ser Thr Cys Asn Arg Leu Phe Thr Ser 
    450                 455                 460                 


Lys His Ser Met Lys Ala His Met Val Arg Gln His Ser Arg Arg Gln 
465                 470                 475                 480 


Asp Leu Leu Pro Gln Leu Glu Ala Pro Ser Ser Leu Thr Pro Ser Ser 
                485                 490                 495     


Glu Leu Ser Ser Pro Gly Gln Ser Glu Leu Thr Asn Met Asp Leu Ala 
            500                 505                 510         


Ala Leu Phe Ser Asp Thr Pro Ala Asn Ala Ser Gly Ser Ala Gly Gly 
        515                 520                 525             


Ser Asp Glu Ala Leu Asn Ser Gly Ile Leu Thr Ile Asp Val Thr Ser 
    530                 535                 540                 


Val Ser Ser Ser Leu Gly Gly Asn Leu Pro Ala Asn Asn Ser Ser Leu 
545                 550                 555                 560 


Gly Pro Met Glu Pro Leu Val Leu Val Ala His Ser Asp Ile Pro Pro 
                565                 570                 575     


Ser Leu Asp Ser Pro Leu Val Leu Gly Thr Ala Ala Thr Val Leu Gln 
            580                 585                 590         


Gln Gly Ser Phe Ser Val Asp Asp Val Gln Thr Val Ser Ala Gly Ala 
        595                 600                 605             


Leu Gly Cys Leu Val Ala Leu Pro Met Lys Asn Leu Ser Asp Asp Pro 
    610                 615                 620                 


Leu Ala Leu Thr Ser Asn Ser Asn Leu Ala Ala His Ile Thr Thr Pro 
625                 630                 635                 640 


Thr Ser Ser Ser Thr Pro Arg Glu Asn Ala Ser Val Pro Glu Leu Leu 
                645                 650                 655     


Ala Pro Ile Lys Val Glu Pro Asp Ser Pro Ser Arg Pro Gly Ala Val 
            660                 665                 670         


Gly Gln Gln Glu Gly Ser His Gly Leu Pro Gln Ser Thr Leu Pro Ser 
        675                 680                 685             


Pro Ala Glu Gln His Gly Ala Gln Asp Thr Glu Leu Ser Ala Gly Thr 
    690                 695                 700                 


Gly Asn Phe Tyr Leu Glu Ser Gly Gly Ser Ala Arg Thr Asp Tyr Arg 
705                 710                 715                 720 


Ala Ile Gln Leu Ala Lys Glu Lys Lys Gln Arg Gly Ala Gly Ser Asn 
                725                 730                 735     


Ala Gly Ala Ser Gln Ser Thr Gln Arg Lys Ile Lys Glu Gly Lys Met 
            740                 745                 750         


Ser Pro Pro His Phe His Ala Ser Gln Asn Ser Trp Leu Cys Gly Ser 
        755                 760                 765             


Leu Val Val Pro Ser Gly Gly Arg Pro Gly Pro Ala Pro Ala Ala Gly 
    770                 775                 780                 


Val Gln Cys Gly Ala Gln Gly Val Gln Val Gln Leu Val Gln Asp Asp 
785                 790                 795                 800 


Pro Ser Gly Glu Gly Val Leu Pro Ser Ala Arg Gly Pro Ala Thr Phe 
                805                 810                 815     


Leu Pro Phe Leu Thr Val Asp Leu Pro Val Tyr Val Leu Gln Glu Val 
            820                 825                 830         


Leu Pro Ser Ser Gly Gly Pro Ala Gly Pro Glu Ala Thr Gln Phe Pro 
        835                 840                 845             


Gly Ser Thr Ile Asn Leu Gln Asp Leu Gln 
    850                 855             


<210>  1272
<211>  632
<212>  PRT
<213>  Human

<400>  1272

Met Val Trp Ala Pro Leu Ser Pro Arg Pro Leu Ser Ser Pro Ser Leu 
1               5                   10                  15      


Leu Leu Pro Cys Val Pro Pro Arg Pro Ala Gly Gly Cys Ser Gly Pro 
            20                  25                  30          


Gly Arg Arg Val Cys Gly Pro Gly Ala Glu Ala Ala Thr Arg Asp Ala 
        35                  40                  45              


Ala Arg Thr Leu Arg Pro Ala Gln Pro Gly Pro Ala Met Ala Ala Pro 
    50                  55                  60                  


Arg Pro Ser Pro Ala Ile Ser Val Ser Val Ser Ala Pro Ala Phe Tyr 
65                  70                  75                  80  


Ala Pro Gln Lys Lys Phe Gly Pro Val Val Ala Pro Lys Pro Lys Val 
                85                  90                  95      


Asn Pro Phe Arg Pro Gly Asp Ser Glu Pro Pro Pro Ala Pro Gly Ala 
            100                 105                 110         


Gln Arg Ala Gln Met Gly Arg Val Gly Glu Ile Pro Pro Pro Pro Pro 
        115                 120                 125             


Glu Asp Phe Pro Leu Pro Pro Pro Pro Leu Ala Gly Asp Gly Asp Asp 
    130                 135                 140                 


Ala Glu Gly Ala Leu Gly Gly Ala Phe Pro Pro Pro Pro Pro Pro Ile 
145                 150                 155                 160 


Glu Glu Ser Phe Pro Pro Ala Pro Leu Glu Glu Glu Ile Phe Pro Ser 
                165                 170                 175     


Pro Pro Pro Pro Pro Glu Glu Glu Gly Gly Pro Glu Ala Pro Ile Pro 
            180                 185                 190         


Pro Pro Pro Gln Pro Arg Glu Lys Val Ser Ser Ile Asp Leu Glu Ile 
        195                 200                 205             


Asp Ser Leu Ser Ser Leu Leu Asp Asp Met Thr Lys Asn Asp Pro Phe 
    210                 215                 220                 


Lys Ala Arg Val Ser Ser Gly Tyr Val Pro Pro Pro Val Ala Thr Pro 
225                 230                 235                 240 


Phe Ser Ser Lys Ser Ser Thr Lys Pro Ala Ala Gly Gly Thr Ala Pro 
                245                 250                 255     


Leu Pro Pro Trp Lys Ser Pro Ser Ser Ser Gln Pro Leu Pro Gln Val 
            260                 265                 270         


Pro Ala Pro Ala Gln Ser Gln Thr Gln Phe His Val Gln Pro Gln Pro 
        275                 280                 285             


Gln Pro Lys Pro Gln Val Gln Leu His Val Gln Ser Gln Thr Gln Pro 
    290                 295                 300                 


Val Ser Leu Ala Asn Thr Gln Pro Arg Gly Pro Pro Ala Ser Ser Pro 
305                 310                 315                 320 


Ala Pro Ala Pro Lys Phe Ser Pro Val Thr Pro Lys Phe Thr Pro Val 
                325                 330                 335     


Ala Ser Lys Phe Ser Pro Gly Ala Pro Gly Gly Ser Gly Ser Gln Pro 
            340                 345                 350         


Asn Gln Lys Leu Gly His Pro Glu Ala Leu Ser Ala Gly Thr Gly Ser 
        355                 360                 365             


Pro Gln Pro Pro Ser Phe Thr Tyr Ala Gln Gln Arg Glu Lys Pro Arg 
    370                 375                 380                 


Val Gln Glu Lys Gln His Pro Val Pro Pro Pro Ala Gln Asn Gln Asn 
385                 390                 395                 400 


Gln Val Arg Ser Pro Gly Ala Pro Gly Pro Leu Thr Leu Lys Glu Val 
                405                 410                 415     


Glu Glu Leu Glu Gln Leu Thr Gln Gln Leu Met Gln Asp Met Glu His 
            420                 425                 430         


Pro Gln Arg Gln Asn Val Ala Val Asn Glu Leu Cys Gly Arg Cys His 
        435                 440                 445             


Gln Pro Leu Ala Arg Ala Gln Pro Ala Val Arg Ala Leu Gly Gln Leu 
    450                 455                 460                 


Phe His Ile Ala Cys Phe Thr Cys His Gln Cys Ala Gln Gln Leu Gln 
465                 470                 475                 480 


Gly Gln Gln Phe Tyr Ser Leu Glu Gly Ala Pro Tyr Cys Glu Gly Cys 
                485                 490                 495     


Tyr Thr Asp Thr Leu Glu Lys Cys Asn Thr Cys Gly Glu Pro Ile Thr 
            500                 505                 510         


Asp Arg Met Leu Arg Ala Thr Gly Lys Ala Tyr His Pro His Cys Phe 
        515                 520                 525             


Thr Cys Val Val Cys Ala Arg Pro Leu Glu Gly Thr Ser Phe Ile Val 
    530                 535                 540                 


Asp Gln Ala Asn Arg Pro His Cys Val Pro Asp Tyr His Lys Gln Tyr 
545                 550                 555                 560 


Ala Pro Arg Cys Ser Val Cys Ser Glu Pro Ile Met Pro Glu Pro Gly 
                565                 570                 575     


Arg Asp Glu Thr Val Arg Val Val Ala Leu Asp Lys Asn Phe His Met 
            580                 585                 590         


Lys Cys Tyr Lys Cys Glu Asp Cys Gly Lys Pro Leu Ser Ile Glu Ala 
        595                 600                 605             


Asp Asp Asn Gly Cys Phe Pro Leu Asp Gly His Val Leu Cys Arg Lys 
    610                 615                 620                 


Cys His Thr Ala Arg Ala Gln Thr 
625                 630         


<210>  1273
<211>  350
<212>  PRT
<213>  Human

<400>  1273

Met Ser Lys Gly Leu Pro Glu Thr Arg Thr Asp Ala Ala Met Ser Glu 
1               5                   10                  15      


Leu Val Pro Glu Pro Arg Pro Lys Pro Ala Val Pro Met Lys Pro Met 
            20                  25                  30          


Ser Ile Asn Ser Asn Leu Leu Gly Tyr Ile Gly Ile Asp Thr Ile Ile 
        35                  40                  45              


Glu Gln Met Arg Lys Lys Thr Met Lys Thr Gly Phe Asp Phe Asn Ile 
    50                  55                  60                  


Met Val Val Gly Gln Ser Gly Leu Gly Lys Ser Thr Leu Val Asn Thr 
65                  70                  75                  80  


Leu Phe Lys Ser Gln Val Ser Arg Lys Ala Ser Ser Trp Asn Arg Glu 
                85                  90                  95      


Glu Lys Ile Pro Lys Thr Val Glu Ile Lys Ala Ile Gly His Val Ile 
            100                 105                 110         


Glu Glu Gly Gly Val Lys Met Lys Leu Thr Val Ile Asp Thr Pro Gly 
        115                 120                 125             


Phe Gly Asp Gln Ile Asn Asn Glu Asn Cys Trp Glu Pro Ile Glu Lys 
    130                 135                 140                 


Tyr Ile Asn Glu Gln Tyr Glu Lys Phe Leu Lys Glu Glu Val Asn Ile 
145                 150                 155                 160 


Ala Arg Lys Lys Arg Ile Pro Asp Thr Arg Val His Cys Cys Leu Tyr 
                165                 170                 175     


Phe Ile Ser Pro Thr Gly His Ser Leu Arg Pro Leu Asp Leu Glu Phe 
            180                 185                 190         


Met Lys His Leu Ser Lys Val Val Asn Ile Ile Pro Val Ile Ala Lys 
        195                 200                 205             


Ala Asp Thr Met Thr Leu Glu Glu Lys Ser Glu Phe Lys Gln Arg Val 
    210                 215                 220                 


Arg Lys Glu Leu Glu Val Asn Gly Ile Glu Phe Tyr Pro Gln Lys Glu 
225                 230                 235                 240 


Phe Asp Glu Asp Leu Glu Asp Lys Thr Glu Asn Asp Lys Ile Arg Gln 
                245                 250                 255     


Glu Ser Met Pro Phe Ala Val Val Gly Ser Asp Lys Glu Tyr Gln Val 
            260                 265                 270         


Asn Gly Lys Arg Val Leu Gly Arg Lys Thr Pro Trp Gly Ile Ile Glu 
        275                 280                 285             


Val Glu Asn Leu Asn His Cys Glu Phe Ala Leu Leu Arg Asp Phe Val 
    290                 295                 300                 


Ile Arg Thr His Leu Gln Asp Leu Lys Glu Val Thr His Asn Ile His 
305                 310                 315                 320 


Tyr Glu Thr Tyr Arg Ala Lys Arg Leu Asn Asp Asn Gly Gly Leu Pro 
                325                 330                 335     


Pro Val Ser Val Asp Thr Glu Glu Ser His Asp Ser Asn Pro 
            340                 345                 350 


<210>  1274
<211>  369
<212>  PRT
<213>  Human

<400>  1274

Met Ser Thr Gly Leu Arg Tyr Lys Ser Lys Leu Ala Thr Pro Glu Asp 
1               5                   10                  15      


Lys Gln Asp Ile Asp Lys Gln Tyr Val Gly Phe Ala Thr Leu Pro Asn 
            20                  25                  30          


Gln Val His Arg Lys Ser Val Lys Lys Gly Phe Asp Phe Thr Leu Met 
        35                  40                  45              


Val Ala Gly Glu Ser Gly Leu Gly Lys Ser Thr Leu Val His Ser Leu 
    50                  55                  60                  


Phe Leu Thr Asp Leu Tyr Lys Asp Arg Lys Leu Leu Ser Ala Glu Glu 
65                  70                  75                  80  


Arg Ile Ser Gln Thr Val Glu Ile Leu Lys His Thr Val Asp Ile Glu 
                85                  90                  95      


Glu Lys Gly Val Lys Leu Lys Leu Thr Ile Val Asp Thr Pro Gly Phe 
            100                 105                 110         


Gly Asp Ala Val Asn Asn Thr Glu Cys Trp Lys Pro Ile Thr Asp Tyr 
        115                 120                 125             


Val Asp Gln Gln Phe Glu Gln Tyr Phe Arg Asp Glu Ser Gly Leu Asn 
    130                 135                 140                 


Arg Lys Asn Ile Gln Asp Asn Arg Val His Cys Cys Leu Tyr Phe Ile 
145                 150                 155                 160 


Ser Pro Phe Gly His Gly Leu Arg Pro Val Asp Val Gly Phe Met Lys 
                165                 170                 175     


Ala Leu His Glu Lys Val Asn Ile Val Pro Leu Ile Ala Lys Ala Asp 
            180                 185                 190         


Cys Leu Val Pro Ser Glu Ile Arg Lys Leu Lys Glu Arg Ile Arg Glu 
        195                 200                 205             


Glu Ile Asp Lys Phe Gly Ile His Val Tyr Gln Phe Pro Glu Cys Asp 
    210                 215                 220                 


Ser Asp Glu Asp Glu Asp Phe Lys Gln Gln Asp Arg Glu Leu Lys Glu 
225                 230                 235                 240 


Ser Ala Pro Phe Ala Val Ile Gly Ser Asn Thr Val Val Glu Ala Lys 
                245                 250                 255     


Gly Gln Arg Val Arg Gly Arg Leu Tyr Pro Trp Gly Ile Val Glu Val 
            260                 265                 270         


Glu Asn Gln Ala His Cys Asp Phe Val Lys Leu Arg Asn Met Leu Ile 
        275                 280                 285             


Arg Thr His Met His Asp Leu Lys Asp Val Thr Cys Asp Val His Tyr 
    290                 295                 300                 


Glu Asn Tyr Arg Ala His Cys Ile Gln Gln Met Thr Ser Lys Leu Thr 
305                 310                 315                 320 


Gln Asp Ser Arg Met Glu Ser Pro Ile Pro Ile Leu Pro Leu Pro Thr 
                325                 330                 335     


Pro Asp Ala Glu Thr Glu Lys Leu Ile Arg Met Lys Asp Glu Glu Leu 
            340                 345                 350         


Arg Arg Met Gln Glu Met Leu Gln Arg Met Lys Gln Gln Met Gln Asp 
        355                 360                 365             


Gln 
    


<210>  1275
<211>  560
<212>  PRT
<213>  Human

<400>  1275

Met Ala Gly Pro Gln Pro Leu Ala Leu Gln Leu Glu Gln Leu Leu Asn 
1               5                   10                  15      


Pro Arg Pro Ser Glu Ala Asp Pro Glu Ala Asp Pro Glu Glu Ala Thr 
            20                  25                  30          


Ala Ala Arg Val Ile Asp Arg Phe Asp Glu Gly Glu Asp Gly Glu Gly 
        35                  40                  45              


Asp Phe Leu Val Val Gly Ser Ile Arg Lys Leu Ala Ser Ala Ser Leu 
    50                  55                  60                  


Leu Asp Thr Asp Lys Arg Tyr Cys Gly Lys Thr Thr Ser Arg Lys Ala 
65                  70                  75                  80  


Trp Asn Glu Asp His Trp Glu Gln Thr Leu Pro Gly Ser Ser Asp Glu 
                85                  90                  95      


Glu Ile Ser Asp Glu Glu Gly Ser Gly Asp Glu Asp Ser Glu Gly Leu 
            100                 105                 110         


Gly Leu Glu Glu Tyr Asp Glu Asp Asp Leu Gly Ala Ala Glu Glu Gln 
        115                 120                 125             


Glu Cys Gly Asp His Arg Glu Ser Lys Lys Ser Arg Ser His Ser Ala 
    130                 135                 140                 


Lys Thr Pro Gly Phe Ser Val Gln Ser Ile Ser Asp Phe Glu Lys Phe 
145                 150                 155                 160 


Thr Lys Gly Met Asp Asp Leu Gly Ser Ser Glu Glu Glu Glu Asp Glu 
                165                 170                 175     


Glu Ser Gly Met Glu Glu Gly Asp Asp Ala Glu Asp Ser Gln Gly Glu 
            180                 185                 190         


Ser Glu Glu Asp Arg Ala Gly Asp Arg Asn Ser Glu Asp Asp Gly Val 
        195                 200                 205             


Val Met Thr Phe Ser Ser Val Lys Val Ser Glu Glu Val Glu Lys Gly 
    210                 215                 220                 


Arg Ala Val Lys Asn Gln Ile Ala Leu Trp Asp Gln Leu Leu Glu Gly 
225                 230                 235                 240 


Arg Ile Lys Leu Gln Lys Ala Leu Leu Thr Thr Asn Gln Leu Pro Gln 
                245                 250                 255     


Pro Asp Val Phe Pro Leu Phe Lys Asp Lys Gly Gly Pro Glu Phe Ser 
            260                 265                 270         


Ser Ala Leu Lys Asn Ser His Lys Ala Leu Lys Ala Leu Leu Arg Ser 
        275                 280                 285             


Leu Val Gly Leu Gln Glu Glu Leu Leu Phe Gln Tyr Pro Asp Thr Arg 
    290                 295                 300                 


Tyr Leu Val Asp Gly Thr Lys Pro Asn Ala Gly Ser Glu Glu Ile Ser 
305                 310                 315                 320 


Ser Glu Asp Asp Glu Leu Val Glu Glu Lys Lys Gln Gln Arg Arg Arg 
                325                 330                 335     


Val Pro Ala Lys Arg Lys Leu Glu Met Glu Asp Tyr Pro Ser Phe Met 
            340                 345                 350         


Ala Lys Arg Phe Ala Asp Phe Thr Val Tyr Arg Asn Arg Thr Leu Gln 
        355                 360                 365             


Lys Trp His Asp Lys Thr Lys Leu Ala Ser Gly Lys Leu Gly Lys Gly 
    370                 375                 380                 


Phe Gly Ala Phe Glu Arg Ser Ile Leu Thr Gln Ile Asp His Ile Leu 
385                 390                 395                 400 


Met Asp Lys Glu Arg Leu Leu Arg Arg Thr Gln Thr Lys Arg Ser Val 
                405                 410                 415     


Tyr Arg Val Leu Gly Lys Pro Glu Pro Ala Ala Gln Pro Val Pro Glu 
            420                 425                 430         


Ser Leu Pro Gly Glu Pro Glu Ile Leu Pro Gln Ala Pro Ala Asn Ala 
        435                 440                 445             


His Leu Lys Asp Leu Asp Glu Glu Ile Phe Asp Asp Asp Asp Phe Tyr 
    450                 455                 460                 


His Gln Leu Leu Arg Glu Leu Ile Glu Arg Lys Thr Ser Ser Leu Asp 
465                 470                 475                 480 


Pro Asn Asp Gln Val Ala Met Gly Arg Gln Trp Leu Ala Ile Gln Lys 
                485                 490                 495     


Leu Arg Ser Lys Ile His Lys Lys Val Asp Arg Lys Ala Ser Lys Gly 
            500                 505                 510         


Arg Lys Leu Arg Phe His Val Leu Ser Lys Leu Leu Ser Phe Met Ala 
        515                 520                 525             


Pro Ile Asp His Thr Thr Met Asn Asp Asp Ala Arg Thr Glu Leu Tyr 
    530                 535                 540                 


Arg Ser Leu Phe Gly Gln Leu His Pro Pro Asp Glu Gly His Gly Asp 
545                 550                 555                 560 


<210>  1276
<211>  319
<212>  PRT
<213>  Human

<400>  1276

Met Cys Ser Leu Pro Val Pro Arg Glu Pro Leu Arg Arg Val Ala Val 
1               5                   10                  15      


Thr Gly Gly Thr His Gly Asn Glu Met Ser Gly Val Tyr Leu Ala Arg 
            20                  25                  30          


His Trp Leu His Ala Pro Ala Glu Leu Gln Arg Ala Ser Phe Ser Ala 
        35                  40                  45              


Val Pro Val Leu Ala Asn Pro Ala Ala Thr Ser Gly Cys Arg Arg Tyr 
    50                  55                  60                  


Val Asp His Asp Leu Asn Arg Thr Phe Thr Ser Ser Phe Leu Asn Ser 
65                  70                  75                  80  


Arg Pro Thr Pro Asp Asp Pro Tyr Glu Val Thr Arg Ala Arg Glu Leu 
                85                  90                  95      


Asn Gln Leu Leu Gly Pro Lys Ala Ser Gly Gln Ala Phe Asp Phe Val 
            100                 105                 110         


Leu Asp Leu His Asn Thr Thr Ala Asn Met Gly Thr Cys Leu Ile Ala 
        115                 120                 125             


Lys Ser Ser His Glu Val Phe Ala Met His Leu Cys Arg His Leu Gln 
    130                 135                 140                 


Leu Gln Tyr Pro Glu Leu Ser Cys Gln Val Phe Leu Tyr Gln Arg Ser 
145                 150                 155                 160 


Gly Glu Glu Ser Tyr Asn Leu Asp Ser Val Ala Lys Asn Gly Leu Gly 
                165                 170                 175     


Leu Glu Leu Gly Pro Gln Pro Gln Gly Val Leu Arg Ala Asp Ile Phe 
            180                 185                 190         


Ser Arg Met Arg Thr Leu Val Ala Thr Val Leu Asp Phe Ile Glu Leu 
        195                 200                 205             


Phe Asn Gln Gly Thr Ala Phe Pro Ala Phe Glu Met Glu Ala Tyr Arg 
    210                 215                 220                 


Pro Val Gly Val Val Asp Phe Pro Arg Thr Glu Ala Gly His Leu Ala 
225                 230                 235                 240 


Gly Thr Val His Pro Gln Leu Gln Asp Arg Asp Phe Gln Pro Leu Gln 
                245                 250                 255     


Pro Gly Ala Pro Ile Phe Gln Met Phe Ser Gly Glu Asp Leu Leu Tyr 
            260                 265                 270         


Glu Gly Glu Ser Thr Val Tyr Pro Val Phe Ile Asn Glu Ala Ala Tyr 
        275                 280                 285             


Tyr Glu Lys Gly Val Ala Phe Val Gln Thr Glu Lys Phe Thr Phe Thr 
    290                 295                 300                 


Val Pro Ala Met Pro Ala Leu Thr Pro Ala Pro Ser Pro Ala Ser 
305                 310                 315                 


<210>  1277
<211>  1211
<212>  PRT
<213>  Human

<400>  1277

Met Asp Pro Pro Ala Gly Ala Ala Arg Arg Leu Leu Cys Pro Ala Leu 
1               5                   10                  15      


Leu Leu Leu Leu Leu Leu Leu Pro Pro Pro Leu Leu Pro Pro Pro Pro 
            20                  25                  30          


Pro Pro Ala Asn Ala Arg Leu Ala Ala Ala Ala Asp Pro Pro Gly Gly 
        35                  40                  45              


Pro Leu Gly His Gly Ala Glu Arg Ile Leu Ala Val Pro Val Arg Thr 
    50                  55                  60                  


Asp Ala Gln Gly Arg Leu Val Ser His Val Val Ser Ala Ala Thr Ser 
65                  70                  75                  80  


Arg Ala Gly Val Arg Ala Arg Arg Ala Ala Pro Val Arg Thr Pro Ser 
                85                  90                  95      


Phe Pro Gly Gly Asn Glu Glu Glu Pro Gly Ser His Leu Phe Tyr Asn 
            100                 105                 110         


Val Thr Val Phe Gly Arg Asp Leu His Leu Arg Leu Arg Pro Asn Ala 
        115                 120                 125             


Arg Leu Val Ala Pro Gly Ala Thr Met Glu Trp Gln Gly Glu Lys Gly 
    130                 135                 140                 


Thr Thr Arg Val Glu Pro Leu Leu Gly Ser Cys Leu Tyr Val Gly Asp 
145                 150                 155                 160 


Val Ala Gly Leu Ala Glu Ala Ser Ser Val Ala Leu Ser Asn Cys Asp 
                165                 170                 175     


Gly Leu Ala Gly Leu Ile Arg Met Glu Glu Glu Glu Phe Phe Ile Glu 
            180                 185                 190         


Pro Leu Glu Lys Gly Leu Ala Ala Gln Glu Ala Glu Gln Gly Arg Val 
        195                 200                 205             


His Val Val Tyr Arg Arg Pro Pro Thr Ser Pro Pro Leu Gly Gly Pro 
    210                 215                 220                 


Gln Ala Leu Asp Thr Gly Ala Ser Leu Asp Ser Leu Asp Ser Leu Ser 
225                 230                 235                 240 


Arg Ala Leu Gly Val Leu Glu Glu His Ala Asn Ser Ser Arg Arg Arg 
                245                 250                 255     


Ala Arg Arg His Ala Ala Asp Asp Asp Tyr Asn Ile Glu Val Leu Leu 
            260                 265                 270         


Gly Val Asp Asp Ser Val Val Gln Phe His Gly Lys Glu His Val Gln 
        275                 280                 285             


Lys Tyr Leu Leu Thr Leu Met Asn Ile Val Asn Glu Ile Tyr His Asp 
    290                 295                 300                 


Glu Ser Leu Gly Ala His Ile Asn Val Val Leu Val Arg Ile Ile Leu 
305                 310                 315                 320 


Leu Ser Tyr Gly Lys Ser Met Ser Leu Ile Glu Ile Gly Asn Pro Ser 
                325                 330                 335     


Gln Ser Leu Glu Asn Val Cys Arg Trp Ala Tyr Leu Gln Gln Lys Pro 
            340                 345                 350         


Asp Thr Gly His Asp Glu Tyr His Asp His Ala Ile Phe Leu Thr Arg 
        355                 360                 365             


Gln Asp Phe Gly Pro Ser Gly Met Gln Gly Tyr Ala Pro Val Thr Gly 
    370                 375                 380                 


Met Cys His Pro Val Arg Ser Cys Thr Leu Asn His Glu Asp Gly Phe 
385                 390                 395                 400 


Ser Ser Ala Phe Val Val Ala His Glu Thr Gly His Val Leu Gly Met 
                405                 410                 415     


Glu His Asp Gly Gln Gly Asn Arg Cys Gly Asp Glu Val Arg Leu Gly 
            420                 425                 430         


Ser Ile Met Ala Pro Leu Val Gln Ala Ala Phe His Arg Phe His Trp 
        435                 440                 445             


Ser Arg Cys Ser Gln Gln Glu Leu Ser Arg Tyr Leu His Ser Tyr Asp 
    450                 455                 460                 


Cys Leu Leu Asp Asp Pro Phe Ala His Asp Trp Pro Ala Leu Pro Gln 
465                 470                 475                 480 


Leu Pro Gly Leu His Tyr Ser Met Asn Glu Gln Cys Arg Phe Asp Phe 
                485                 490                 495     


Gly Leu Gly Tyr Met Met Cys Thr Ala Phe Arg Thr Phe Asp Pro Cys 
            500                 505                 510         


Lys Gln Leu Trp Cys Ser His Pro Asp Asn Pro Tyr Phe Cys Lys Thr 
        515                 520                 525             


Lys Lys Gly Pro Pro Leu Asp Gly Thr Met Cys Ala Pro Gly Lys His 
    530                 535                 540                 


Cys Phe Lys Gly His Cys Ile Trp Leu Thr Pro Asp Ile Leu Lys Arg 
545                 550                 555                 560 


Asp Gly Ser Trp Gly Ala Trp Ser Pro Phe Gly Ser Cys Ser Arg Thr 
                565                 570                 575     


Cys Gly Thr Gly Val Lys Phe Arg Thr Arg Gln Cys Asp Asn Pro His 
            580                 585                 590         


Pro Ala Asn Gly Gly Arg Thr Cys Ser Gly Leu Ala Tyr Asp Phe Gln 
        595                 600                 605             


Leu Cys Ser Arg Gln Asp Cys Pro Asp Ser Leu Ala Asp Phe Arg Glu 
    610                 615                 620                 


Glu Gln Cys Arg Gln Trp Asp Leu Tyr Phe Glu His Gly Asp Ala Gln 
625                 630                 635                 640 


His His Trp Leu Pro His Glu His Arg Asp Ala Lys Glu Arg Cys His 
                645                 650                 655     


Leu Tyr Cys Glu Ser Arg Glu Thr Gly Glu Val Val Ser Met Lys Arg 
            660                 665                 670         


Met Val His Asp Gly Thr Arg Cys Ser Tyr Lys Asp Ala Phe Ser Leu 
        675                 680                 685             


Cys Val Arg Gly Asp Cys Arg Lys Val Gly Cys Asp Gly Val Ile Gly 
    690                 695                 700                 


Ser Ser Lys Gln Glu Asp Lys Cys Gly Val Cys Gly Gly Asp Asn Ser 
705                 710                 715                 720 


His Cys Lys Val Val Lys Gly Thr Phe Thr Arg Ser Pro Lys Lys His 
                725                 730                 735     


Gly Tyr Ile Lys Met Phe Glu Ile Pro Ala Gly Ala Arg His Leu Leu 
            740                 745                 750         


Ile Gln Glu Val Asp Ala Thr Ser His His Leu Ala Val Lys Asn Leu 
        755                 760                 765             


Glu Thr Gly Lys Phe Ile Leu Asn Glu Glu Asn Asp Val Asp Ala Ser 
    770                 775                 780                 


Ser Lys Thr Phe Ile Ala Met Gly Val Glu Trp Glu Tyr Arg Asp Glu 
785                 790                 795                 800 


Asp Gly Arg Glu Thr Leu Gln Thr Met Gly Pro Leu His Gly Thr Ile 
                805                 810                 815     


Thr Val Leu Val Ile Pro Val Gly Asp Thr Arg Val Ser Leu Thr Tyr 
            820                 825                 830         


Lys Tyr Met Ile His Glu Asp Ser Leu Asn Val Asp Asp Asn Asn Val 
        835                 840                 845             


Leu Glu Glu Asp Ser Val Val Tyr Glu Trp Ala Leu Lys Lys Trp Ser 
    850                 855                 860                 


Pro Cys Ser Lys Pro Cys Gly Gly Gly Ser Gln Phe Thr Lys Tyr Gly 
865                 870                 875                 880 


Cys Arg Arg Arg Leu Asp His Lys Met Val His Arg Gly Phe Cys Ala 
                885                 890                 895     


Ala Leu Ser Lys Pro Lys Ala Ile Arg Arg Ala Cys Asn Pro Gln Glu 
            900                 905                 910         


Cys Ser Gln Pro Val Trp Val Thr Gly Glu Trp Glu Pro Cys Ser Gln 
        915                 920                 925             


Thr Cys Gly Arg Thr Gly Met Gln Val Arg Ser Val Arg Cys Ile Gln 
    930                 935                 940                 


Pro Leu His Asp Asn Thr Thr Arg Ser Val His Ala Lys His Cys Asn 
945                 950                 955                 960 


Asp Ala Arg Pro Glu Ser Arg Arg Ala Cys Ser Arg Glu Leu Cys Pro 
                965                 970                 975     


Gly Arg Trp Arg Ala Gly Pro Trp Ser Gln Cys Ser Val Thr Cys Gly 
            980                 985                 990         


Asn Gly Thr Gln Glu Arg Pro Val  Leu Cys Arg Thr Ala  Asp Asp Ser 
        995                 1000                 1005             


Phe Gly  Ile Cys Gln Glu Glu  Arg Pro Glu Thr Ala  Arg Thr Cys 
    1010                 1015                 1020             


Arg Leu  Gly Pro Cys Pro Arg  Asn Ile Ser Asp Pro  Ser Lys Lys 
    1025                 1030                 1035             


Ser Tyr  Val Val Gln Trp Leu  Ser Arg Pro Asp Pro  Asp Ser Pro 
    1040                 1045                 1050             


Ile Arg  Lys Ile Ser Ser Lys  Gly His Cys Gln Gly  Asp Lys Ser 
    1055                 1060                 1065             


Ile Phe  Cys Arg Met Glu Val  Leu Ser Arg Tyr Cys  Ser Ile Pro 
    1070                 1075                 1080             


Gly Tyr  Asn Lys Leu Cys Cys  Lys Ser Cys Asn Leu  Tyr Asn Asn 
    1085                 1090                 1095             


Leu Thr  Asn Val Glu Gly Arg  Ile Glu Pro Pro Pro  Gly Lys His 
    1100                 1105                 1110             


Asn Asp  Ile Asp Val Phe Met  Pro Thr Leu Pro Val  Pro Thr Val 
    1115                 1120                 1125             


Ala Met  Glu Val Arg Pro Ser  Pro Ser Thr Pro Leu  Glu Val Pro 
    1130                 1135                 1140             


Leu Asn  Ala Ser Ser Thr Asn  Ala Thr Glu Asp His  Pro Glu Thr 
    1145                 1150                 1155             


Asn Ala  Val Asp Glu Pro Tyr  Lys Ile His Gly Leu  Glu Asp Glu 
    1160                 1165                 1170             


Val Gln  Pro Pro Asn Leu Ile  Pro Arg Arg Pro Ser  Pro Tyr Glu 
    1175                 1180                 1185             


Lys Thr  Arg Asn Gln Arg Ile  Gln Glu Leu Ile Asp  Glu Met Arg 
    1190                 1195                 1200             


Lys Lys  Glu Met Leu Gly Lys  Phe 
    1205                 1210     


<210>  1278
<211>  797
<212>  PRT
<213>  Human

<400>  1278

Met Ala His Arg Cys Leu Arg Leu Trp Gly Arg Gly Gly Cys Trp Pro 
1               5                   10                  15      


Arg Gly Leu Gln Gln Leu Leu Val Pro Gly Gly Val Gly Pro Gly Glu 
            20                  25                  30          


Gln Pro Cys Leu Arg Thr Leu Tyr Arg Phe Val Thr Thr Gln Ala Arg 
        35                  40                  45              


Ala Ser Arg Asn Ser Leu Leu Thr Asp Ile Ile Ala Ala Tyr Gln Arg 
    50                  55                  60                  


Phe Cys Ser Arg Pro Pro Lys Gly Phe Gly Lys Tyr Phe Pro Asn Gly 
65                  70                  75                  80  


Lys Asn Gly Lys Lys Ala Ser Glu Pro Lys Glu Val Met Gly Glu Lys 
                85                  90                  95      


Lys Glu Ser Lys Pro Ala Ala Thr Thr Arg Ser Ser Gly Gly Gly Gly 
            100                 105                 110         


Gly Gly Gly Gly Lys Arg Gly Gly Lys Lys Asp Asp Ser His Trp Trp 
        115                 120                 125             


Ser Arg Phe Gln Lys Gly Asp Ile Pro Trp Asp Asp Lys Asp Phe Arg 
    130                 135                 140                 


Met Phe Phe Leu Trp Thr Ala Leu Phe Trp Gly Gly Val Met Phe Tyr 
145                 150                 155                 160 


Leu Leu Leu Lys Arg Ser Gly Arg Glu Ile Thr Trp Lys Asp Phe Val 
                165                 170                 175     


Asn Asn Tyr Leu Ser Lys Gly Val Val Asp Arg Leu Glu Val Val Asn 
            180                 185                 190         


Lys Arg Phe Val Arg Val Thr Phe Thr Pro Gly Lys Thr Pro Val Asp 
        195                 200                 205             


Gly Gln Tyr Val Trp Phe Asn Ile Gly Ser Val Asp Thr Phe Glu Arg 
    210                 215                 220                 


Asn Leu Glu Thr Leu Gln Gln Glu Leu Gly Ile Glu Gly Glu Asn Arg 
225                 230                 235                 240 


Val Pro Val Val Tyr Ile Ala Glu Ser Asp Gly Ser Phe Leu Leu Ser 
                245                 250                 255     


Met Leu Pro Thr Val Leu Ile Ile Ala Phe Leu Leu Tyr Thr Ile Arg 
            260                 265                 270         


Arg Gly Pro Ala Gly Ile Gly Arg Thr Gly Arg Gly Met Gly Gly Leu 
        275                 280                 285             


Phe Ser Val Gly Glu Thr Thr Ala Lys Val Leu Lys Asp Glu Ile Asp 
    290                 295                 300                 


Val Lys Phe Lys Asp Val Ala Gly Cys Glu Glu Ala Lys Leu Glu Ile 
305                 310                 315                 320 


Met Glu Phe Val Asn Phe Leu Lys Asn Pro Lys Gln Tyr Gln Asp Leu 
                325                 330                 335     


Gly Ala Lys Ile Pro Lys Gly Ala Ile Leu Thr Gly Pro Pro Gly Thr 
            340                 345                 350         


Gly Lys Thr Leu Leu Ala Lys Ala Thr Ala Gly Glu Ala Asn Val Pro 
        355                 360                 365             


Phe Ile Thr Val Ser Gly Ser Glu Phe Leu Glu Met Phe Val Gly Val 
    370                 375                 380                 


Gly Pro Ala Arg Val Arg Asp Leu Phe Ala Leu Ala Arg Lys Asn Ala 
385                 390                 395                 400 


Pro Cys Ile Leu Phe Ile Asp Glu Ile Asp Ala Val Gly Arg Lys Arg 
                405                 410                 415     


Gly Arg Gly Asn Phe Gly Gly Gln Ser Glu Gln Glu Asn Thr Leu Asn 
            420                 425                 430         


Gln Leu Leu Val Glu Met Asp Gly Phe Asn Thr Thr Thr Asn Val Val 
        435                 440                 445             


Ile Leu Ala Gly Thr Asn Arg Pro Asp Ile Leu Asp Pro Ala Leu Leu 
    450                 455                 460                 


Arg Pro Gly Arg Phe Asp Arg Gln Ile Phe Ile Gly Pro Pro Asp Ile 
465                 470                 475                 480 


Lys Gly Arg Ala Ser Ile Phe Lys Val His Leu Arg Pro Leu Lys Leu 
                485                 490                 495     


Asp Ser Thr Leu Glu Lys Asp Lys Leu Ala Arg Lys Leu Ala Ser Leu 
            500                 505                 510         


Thr Pro Gly Phe Ser Gly Ala Asp Val Ala Asn Val Cys Asn Glu Ala 
        515                 520                 525             


Ala Leu Ile Ala Ala Arg His Leu Ser Asp Ser Ile Asn Gln Lys His 
    530                 535                 540                 


Phe Glu Gln Ala Ile Glu Arg Val Ile Gly Gly Leu Glu Lys Lys Thr 
545                 550                 555                 560 


Gln Val Leu Gln Pro Glu Glu Lys Lys Thr Val Ala Tyr His Glu Ala 
                565                 570                 575     


Gly His Ala Val Ala Gly Trp Tyr Leu Glu His Ala Asp Pro Leu Leu 
            580                 585                 590         


Lys Val Ser Ile Ile Pro Arg Gly Lys Gly Leu Gly Tyr Ala Gln Tyr 
        595                 600                 605             


Leu Pro Lys Glu Gln Tyr Leu Tyr Thr Lys Glu Gln Leu Leu Asp Arg 
    610                 615                 620                 


Met Cys Met Thr Leu Gly Gly Arg Ala Ser Glu Glu Ile Phe Phe Gly 
625                 630                 635                 640 


Arg Ile Thr Thr Gly Ala Gln Asp Asp Leu Arg Lys Val Thr Gln Ser 
                645                 650                 655     


Ala Tyr Ala Gln Ile Val Gln Phe Gly Met Asn Glu Lys Val Gly Gln 
            660                 665                 670         


Ile Ser Phe Asp Leu Pro Arg Gln Gly Asp Met Val Leu Glu Lys Pro 
        675                 680                 685             


Tyr Ser Glu Ala Thr Ala Arg Leu Ile Asp Asp Glu Val Arg Ile Leu 
    690                 695                 700                 


Ile Asn Asp Ala Tyr Lys Arg Thr Val Ala Leu Leu Thr Glu Lys Lys 
705                 710                 715                 720 


Ala Asp Val Glu Lys Val Ala Leu Leu Leu Leu Glu Lys Glu Val Leu 
                725                 730                 735     


Asp Lys Asn Asp Met Val Glu Leu Leu Gly Pro Arg Pro Phe Ala Glu 
            740                 745                 750         


Lys Ser Thr Tyr Glu Glu Phe Val Glu Gly Thr Gly Ser Leu Asp Glu 
        755                 760                 765             


Asp Thr Ser Leu Pro Glu Gly Leu Lys Asp Trp Asn Lys Glu Arg Glu 
    770                 775                 780                 


Lys Glu Lys Glu Glu Pro Pro Gly Glu Lys Val Ala Asn 
785                 790                 795         


<210>  1279
<211>  323
<212>  PRT
<213>  Human

<400>  1279

Met Asp Ser Lys Tyr Gln Cys Val Lys Leu Asn Asp Gly His Phe Met 
1               5                   10                  15      


Pro Val Leu Gly Phe Gly Thr Tyr Ala Pro Ala Glu Val Pro Lys Ser 
            20                  25                  30          


Lys Ala Leu Glu Ala Val Lys Leu Ala Ile Glu Ala Gly Phe His His 
        35                  40                  45              


Ile Asp Ser Ala His Val Tyr Asn Asn Glu Glu Gln Val Gly Leu Ala 
    50                  55                  60                  


Ile Arg Ser Lys Ile Ala Asp Gly Ser Val Lys Arg Glu Asp Ile Phe 
65                  70                  75                  80  


Tyr Thr Ser Lys Leu Trp Ser Asn Ser His Arg Pro Glu Leu Val Arg 
                85                  90                  95      


Pro Ala Leu Glu Arg Ser Leu Lys Asn Leu Gln Leu Asp Tyr Val Asp 
            100                 105                 110         


Leu Tyr Leu Ile His Phe Pro Val Ser Val Lys Pro Gly Glu Glu Val 
        115                 120                 125             


Ile Pro Lys Asp Glu Asn Gly Lys Ile Leu Phe Asp Thr Val Asp Leu 
    130                 135                 140                 


Cys Ala Thr Trp Glu Ala Met Glu Lys Cys Lys Asp Ala Gly Leu Ala 
145                 150                 155                 160 


Lys Ser Ile Gly Val Ser Asn Phe Asn His Arg Leu Leu Glu Met Ile 
                165                 170                 175     


Leu Asn Lys Pro Gly Leu Lys Tyr Lys Pro Val Cys Asn Gln Val Glu 
            180                 185                 190         


Cys His Pro Tyr Phe Asn Gln Arg Lys Leu Leu Asp Phe Cys Lys Ser 
        195                 200                 205             


Lys Asp Ile Val Leu Val Ala Tyr Ser Ala Leu Gly Ser His Arg Glu 
    210                 215                 220                 


Glu Pro Trp Val Asp Pro Asn Ser Pro Val Leu Leu Glu Asp Pro Val 
225                 230                 235                 240 


Leu Cys Ala Leu Ala Lys Lys His Lys Arg Thr Pro Ala Leu Ile Ala 
                245                 250                 255     


Leu Arg Tyr Gln Leu Gln Arg Gly Val Val Val Leu Ala Lys Ser Tyr 
            260                 265                 270         


Asn Glu Gln Arg Ile Arg Gln Asn Val Gln Val Phe Glu Phe Gln Leu 
        275                 280                 285             


Thr Ser Glu Glu Met Lys Ala Ile Asp Gly Leu Asn Arg Asn Val Arg 
    290                 295                 300                 


Tyr Leu Thr Leu Asp Ile Phe Ala Gly Pro Pro Asn Tyr Pro Phe Ser 
305                 310                 315                 320 


Asp Glu Tyr 
            


<210>  1280
<211>  643
<212>  PRT
<213>  Human

<400>  1280

Met Pro Leu Leu Phe Leu Glu Arg Phe Pro Trp Pro Ser Leu Arg Thr 
1               5                   10                  15      


Tyr Thr Gly Leu Ser Gly Leu Ala Leu Leu Gly Thr Ile Ile Ser Ala 
            20                  25                  30          


Tyr Arg Ala Leu Ser Gln Pro Glu Ala Gly Pro Gly Glu Pro Asp Gln 
        35                  40                  45              


Leu Thr Ala Ser Leu Gln Pro Glu Pro Pro Ala Pro Ala Arg Pro Ser 
    50                  55                  60                  


Ala Gly Gly Pro Arg Ala Arg Asp Val Ala Gln Tyr Leu Leu Ser Asp 
65                  70                  75                  80  


Ser Leu Phe Val Trp Val Leu Val Asn Thr Ala Cys Cys Val Leu Met 
                85                  90                  95      


Leu Val Ala Lys Leu Ile Gln Cys Ile Val Phe Gly Pro Leu Arg Val 
            100                 105                 110         


Ser Glu Arg Gln His Leu Lys Asp Lys Phe Trp Asn Phe Ile Phe Tyr 
        115                 120                 125             


Lys Phe Ile Phe Ile Phe Gly Val Leu Asn Val Gln Thr Val Glu Glu 
    130                 135                 140                 


Val Val Met Trp Cys Leu Trp Phe Ala Gly Leu Val Phe Leu His Leu 
145                 150                 155                 160 


Met Val Gln Leu Cys Lys Asp Arg Phe Glu Tyr Leu Ser Phe Ser Pro 
                165                 170                 175     


Thr Thr Pro Met Ser Ser His Gly Arg Val Leu Ser Leu Leu Val Ala 
            180                 185                 190         


Met Leu Leu Ser Cys Cys Gly Leu Ala Ala Val Cys Ser Ile Thr Gly 
        195                 200                 205             


Tyr Thr His Gly Met His Thr Leu Ala Phe Met Ala Ala Glu Ser Leu 
    210                 215                 220                 


Leu Val Thr Val Arg Thr Ala His Val Ile Leu Arg Tyr Val Ile His 
225                 230                 235                 240 


Leu Trp Asp Leu Asn His Glu Gly Thr Trp Glu Gly Lys Gly Thr Tyr 
                245                 250                 255     


Val Tyr Tyr Thr Asp Phe Val Met Glu Leu Thr Leu Leu Ser Leu Asp 
            260                 265                 270         


Leu Met His His Ile His Met Leu Leu Phe Gly Asn Ile Trp Leu Ser 
        275                 280                 285             


Met Ala Ser Leu Val Ile Phe Met Gln Leu Arg Tyr Leu Phe His Glu 
    290                 295                 300                 


Val Gln Arg Arg Ile Arg Arg His Lys Asn Tyr Leu Arg Val Val Gly 
305                 310                 315                 320 


Asn Met Glu Ala Arg Phe Ala Val Ala Thr Pro Glu Glu Leu Ala Val 
                325                 330                 335     


Asn Asn Asp Asp Cys Ala Ile Cys Trp Asp Ser Met Gln Ala Ala Arg 
            340                 345                 350         


Lys Leu Pro Cys Gly His Leu Phe His Asn Ser Cys Leu Arg Ser Trp 
        355                 360                 365             


Leu Glu Gln Asp Thr Ser Cys Pro Thr Cys Arg Met Ser Leu Asn Ile 
    370                 375                 380                 


Ala Asp Asn Asn Arg Val Arg Glu Glu His Gln Gly Glu Asn Leu Asp 
385                 390                 395                 400 


Glu Asn Leu Val Pro Val Ala Ala Ala Glu Gly Arg Pro Arg Leu Asn 
                405                 410                 415     


Gln His Asn His Phe Phe His Phe Asp Gly Ser Arg Ile Ala Ser Trp 
            420                 425                 430         


Leu Pro Ser Phe Ser Val Glu Val Met His Thr Thr Asn Ile Leu Gly 
        435                 440                 445             


Ile Thr Gln Ala Ser Asn Ser Gln Leu Asn Ala Met Ala His Gln Ile 
    450                 455                 460                 


Gln Glu Met Phe Pro Gln Val Pro Tyr His Leu Val Leu Gln Asp Leu 
465                 470                 475                 480 


Gln Leu Thr Arg Ser Val Glu Ile Thr Thr Asp Asn Ile Leu Glu Gly 
                485                 490                 495     


Arg Ile Gln Val Pro Phe Pro Thr Gln Arg Ser Asp Ser Ile Arg Pro 
            500                 505                 510         


Ala Leu Asn Ser Pro Val Glu Arg Pro Ser Ser Asp Gln Glu Glu Gly 
        515                 520                 525             


Glu Thr Ser Ala Gln Thr Glu Arg Val Pro Leu Asp Leu Ser Pro Arg 
    530                 535                 540                 


Leu Glu Glu Thr Leu Asp Phe Gly Glu Val Glu Val Glu Pro Ser Glu 
545                 550                 555                 560 


Val Glu Asp Phe Glu Ala Arg Gly Ser Arg Phe Ser Lys Ser Ala Asp 
                565                 570                 575     


Glu Arg Gln Arg Met Leu Val Gln Arg Lys Asp Glu Leu Leu Gln Gln 
            580                 585                 590         


Ala Arg Lys Arg Phe Leu Asn Lys Ser Ser Glu Asp Asp Ala Ala Ser 
        595                 600                 605             


Glu Ser Phe Leu Pro Ser Glu Gly Ala Ser Ser Asp Pro Val Thr Leu 
    610                 615                 620                 


Arg Arg Arg Met Leu Ala Ala Ala Ala Glu Arg Arg Leu Gln Lys Gln 
625                 630                 635                 640 


Gln Thr Ser 
            


<210>  1281
<211>  812
<212>  PRT
<213>  Human

<400>  1281

Met Ser Glu Gln Gly Asp Leu Asn Gln Ala Ile Ala Glu Glu Gly Gly 
1               5                   10                  15      


Thr Glu Gln Glu Thr Ala Thr Pro Glu Asn Gly Ile Val Lys Ser Glu 
            20                  25                  30          


Ser Leu Asp Glu Glu Glu Lys Leu Glu Leu Gln Arg Arg Leu Glu Ala 
        35                  40                  45              


Gln Asn Gln Glu Arg Arg Lys Ser Lys Ser Gly Ala Gly Lys Gly Lys 
    50                  55                  60                  


Leu Thr Arg Ser Leu Ala Val Cys Glu Glu Ser Ser Ala Arg Pro Gly 
65                  70                  75                  80  


Gly Glu Ser Leu Gln Asp Gln Glu Ser Ile His Leu Gln Leu Ser Ser 
                85                  90                  95      


Phe Ser Ser Leu Gln Glu Glu Asp Lys Ser Arg Lys Asp Asp Ser Glu 
            100                 105                 110         


Arg Glu Lys Glu Lys Asp Lys Asn Lys Asp Lys Thr Ser Glu Lys Pro 
        115                 120                 125             


Lys Ile Arg Met Leu Ser Lys Asp Cys Ser Gln Glu Tyr Thr Asp Ser 
    130                 135                 140                 


Thr Gly Ile Asp Leu His Glu Phe Leu Ile Asn Thr Leu Lys Asn Asn 
145                 150                 155                 160 


Ser Arg Asp Arg Met Ile Leu Leu Lys Met Glu Gln Glu Ile Ile Asp 
                165                 170                 175     


Phe Ile Ala Asp Asn Asn Asn His Tyr Lys Lys Phe Pro Gln Met Ser 
            180                 185                 190         


Ser Tyr Gln Arg Met Leu Val His Arg Val Ala Ala Tyr Phe Gly Leu 
        195                 200                 205             


Asp His Asn Val Asp Gln Thr Gly Lys Ser Val Ile Ile Asn Lys Thr 
    210                 215                 220                 


Ser Ser Thr Arg Ile Pro Glu Gln Arg Phe Cys Glu His Leu Lys Asp 
225                 230                 235                 240 


Glu Lys Gly Glu Glu Ser Gln Lys Arg Phe Ile Leu Lys Arg Asp Asn 
                245                 250                 255     


Ser Ser Ile Asp Lys Glu Asp Asn Gln Gln Asn Arg Met His Pro Phe 
            260                 265                 270         


Arg Asp Asp Arg Arg Ser Lys Ser Ile Glu Glu Arg Glu Glu Glu Tyr 
        275                 280                 285             


Gln Arg Val Arg Glu Arg Ile Phe Ala His Asp Ser Val Cys Ser Gln 
    290                 295                 300                 


Glu Ser Leu Phe Val Glu Asn Ser Arg Leu Leu Glu Asp Ser Asn Ile 
305                 310                 315                 320 


Cys Asn Glu Thr Tyr Lys Lys Arg Gln Leu Phe Arg Gly Asn Arg Asp 
                325                 330                 335     


Gly Ser Gly Arg Thr Ser Gly Ser Arg Gln Ser Ser Ser Glu Asn Glu 
            340                 345                 350         


Leu Lys Trp Ser Asp His Gln Arg Ala Trp Ser Ser Thr Asp Ser Asp 
        355                 360                 365             


Ser Ser Asn Arg Asn Leu Lys Pro Ala Met Thr Lys Thr Ala Ser Phe 
    370                 375                 380                 


Gly Gly Ile Thr Val Leu Thr Arg Gly Asp Ser Thr Ser Ser Thr Arg 
385                 390                 395                 400 


Ser Thr Gly Lys Leu Ser Lys Ala Gly Ser Glu Ser Ser Ser Ser Ala 
                405                 410                 415     


Gly Ser Ser Gly Ser Leu Ser Arg Thr His Pro Pro Leu Gln Ser Thr 
            420                 425                 430         


Pro Leu Val Ser Gly Val Ala Ala Gly Ser Pro Gly Cys Val Pro Tyr 
        435                 440                 445             


Pro Glu Asn Gly Ile Gly Gly Gln Val Ala Pro Ser Ser Thr Ser Tyr 
    450                 455                 460                 


Ile Leu Leu Pro Leu Glu Ala Ala Thr Gly Ile Pro Pro Gly Ser Ile 
465                 470                 475                 480 


Leu Leu Asn Pro His Thr Gly Gln Pro Phe Val Asn Pro Asp Gly Thr 
                485                 490                 495     


Pro Ala Ile Tyr Asn Pro Pro Thr Ser Gln Gln Pro Leu Arg Ser Ala 
            500                 505                 510         


Met Val Gly Gln Ser Gln Gln Gln Pro Pro Gln Gln Gln Pro Ser Pro 
        515                 520                 525             


Gln Pro Gln Gln Gln Val Gln Pro Pro Gln Pro Gln Met Ala Gly Pro 
    530                 535                 540                 


Leu Val Thr Gln Arg Asp Asp Val Ala Thr Gln Phe Gly Gln Met Thr 
545                 550                 555                 560 


Leu Ser Arg Gln Ser Ser Gly Glu Thr Pro Glu Pro Pro Ser Gly Pro 
                565                 570                 575     


Val Tyr Pro Ser Ser Leu Met Pro Gln Pro Ala Gln Gln Pro Ser Tyr 
            580                 585                 590         


Val Ile Ala Ser Thr Gly Gln Gln Leu Pro Thr Gly Gly Phe Ser Gly 
        595                 600                 605             


Ser Gly Pro Pro Ile Ser Gln Gln Val Leu Gln Pro Pro Pro Ser Pro 
    610                 615                 620                 


Gln Gly Phe Val Gln Gln Pro Pro Pro Ala Gln Met Pro Val Tyr Tyr 
625                 630                 635                 640 


Tyr Pro Ser Gly Gln Tyr Pro Thr Ser Thr Thr Gln Gln Tyr Arg Pro 
                645                 650                 655     


Met Ala Pro Val Gln Tyr Asn Ala Gln Arg Ser Gln Gln Met Pro Gln 
            660                 665                 670         


Ala Ala Gln Gln Ala Gly Tyr Gln Pro Val Leu Ser Gly Gln Gln Gly 
        675                 680                 685             


Phe Gln Gly Leu Ile Gly Val Gln Gln Pro Pro Gln Ser Gln Asn Val 
    690                 695                 700                 


Ile Asn Asn Gln Gln Gly Thr Pro Val Gln Ser Val Met Val Ser Tyr 
705                 710                 715                 720 


Pro Thr Met Ser Ser Tyr Gln Val Pro Met Thr Gln Gly Ser Gln Gly 
                725                 730                 735     


Leu Pro Gln Gln Ser Tyr Gln Gln Pro Ile Met Leu Pro Asn Gln Ala 
            740                 745                 750         


Gly Gln Gly Ser Leu Pro Ala Thr Gly Met Pro Val Tyr Cys Asn Val 
        755                 760                 765             


Thr Pro Pro Thr Pro Gln Asn Asn Leu Arg Leu Ile Gly Pro His Cys 
    770                 775                 780                 


Pro Ser Ser Thr Val Pro Val Met Ser Ala Ser Cys Arg Thr Asn Cys 
785                 790                 795                 800 


Ala Ser Met Ser Asn Ala Gly Trp Gln Val Lys Phe 
                805                 810         


<210>  1282
<211>  962
<212>  PRT
<213>  Human

<400>  1282

Met Glu Asp Cys Asn Val His Ser Ala Ala Ser Ile Leu Ala Ser Val 
1               5                   10                  15      


Lys Glu Gln Glu Ala Arg Phe Glu Arg Leu Thr Arg Ala Leu Glu Gln 
            20                  25                  30          


Glu Arg Arg His Val Ala Leu Gln Leu Glu Arg Ala Gln Gln Pro Gly 
        35                  40                  45              


Met Val Ser Gly Gly Met Gly Ser Gly Gln Pro Leu Pro Met Ala Trp 
    50                  55                  60                  


Gln Gln Leu Val Leu Gln Glu Gln Ser Pro Gly Ser Gln Ala Ser Leu 
65                  70                  75                  80  


Ala Thr Met Pro Glu Ala Pro Asp Val Leu Glu Glu Thr Val Thr Val 
                85                  90                  95      


Glu Glu Asp Pro Gly Thr Pro Thr Ser His Val Ser Ile Val Thr Ser 
            100                 105                 110         


Glu Asp Gly Thr Thr Arg Arg Thr Glu Thr Lys Val Thr Lys Thr Val 
        115                 120                 125             


Lys Thr Val Thr Thr Arg Thr Val Arg Gln Val Pro Val Gly Pro Asp 
    130                 135                 140                 


Gly Leu Pro Leu Leu Asp Gly Gly Pro Pro Leu Gly Pro Phe Ala Asp 
145                 150                 155                 160 


Gly Ala Leu Asp Arg His Phe Leu Leu Arg Gly Gly Gly Pro Val Ala 
                165                 170                 175     


Thr Leu Ser Arg Ala Tyr Leu Ser Ser Gly Gly Gly Phe Pro Glu Gly 
            180                 185                 190         


Pro Glu Pro Arg Asp Ser Pro Ser Tyr Gly Ser Leu Ser Arg Gly Leu 
        195                 200                 205             


Gly Met Arg Pro Pro Arg Ala Gly Pro Leu Gly Pro Gly Pro Gly Asp 
    210                 215                 220                 


Gly Cys Phe Thr Leu Pro Gly His Arg Glu Ala Phe Pro Val Gly Pro 
225                 230                 235                 240 


Glu Pro Gly Pro Pro Gly Gly Arg Ser Leu Pro Glu Arg Phe Gln Ala 
                245                 250                 255     


Glu Pro Tyr Gly Leu Glu Asp Asp Thr Arg Ser Leu Ala Ala Asp Asp 
            260                 265                 270         


Glu Gly Gly Pro Glu Leu Glu Pro Asp Tyr Gly Thr Ala Thr Arg Arg 
        275                 280                 285             


Arg Pro Glu Cys Gly Arg Gly Leu His Thr Arg Ala Tyr Glu Asp Thr 
    290                 295                 300                 


Ala Asp Asp Gly Gly Glu Leu Ala Asp Glu Arg Pro Ala Phe Pro Met 
305                 310                 315                 320 


Val Thr Ala Pro Leu Ala Gln Pro Glu Arg Gly Ser Met Gly Ser Leu 
                325                 330                 335     


Asp Arg Leu Val Arg Arg Ser Pro Ser Val Asp Ser Ala Arg Lys Glu 
            340                 345                 350         


Pro Arg Trp Arg Asp Pro Glu Leu Pro Glu Val Leu Ala Met Leu Arg 
        355                 360                 365             


His Pro Val Asp Pro Val Lys Ala Asn Ala Ala Ala Tyr Leu Gln His 
    370                 375                 380                 


Leu Cys Phe Glu Asn Glu Gly Val Lys Arg Arg Val Arg Gln Leu Arg 
385                 390                 395                 400 


Gly Leu Pro Leu Leu Val Ala Leu Leu Asp His Pro Arg Ala Glu Val 
                405                 410                 415     


Arg Arg Arg Ala Cys Gly Ala Leu Arg Asn Leu Ser Tyr Gly Arg Asp 
            420                 425                 430         


Thr Asp Asn Lys Ala Ala Ile Arg Asp Cys Gly Gly Val Pro Ala Leu 
        435                 440                 445             


Val Arg Leu Leu Arg Ala Ala Arg Asp Asn Glu Val Arg Glu Leu Val 
    450                 455                 460                 


Thr Gly Thr Leu Trp Asn Leu Ser Ser Tyr Glu Pro Leu Lys Met Val 
465                 470                 475                 480 


Ile Ile Asp His Gly Leu Gln Thr Leu Thr His Glu Val Ile Val Pro 
                485                 490                 495     


His Ser Gly Trp Glu Arg Glu Pro Asn Glu Asp Ser Lys Pro Arg Asp 
            500                 505                 510         


Ala Glu Trp Thr Thr Val Phe Lys Asn Thr Ser Gly Cys Leu Arg Asn 
        515                 520                 525             


Val Ser Ser Asp Gly Ala Glu Ala Arg Arg Arg Leu Arg Glu Cys Glu 
    530                 535                 540                 


Gly Leu Val Asp Ala Leu Leu His Ala Leu Gln Ser Ala Val Gly Arg 
545                 550                 555                 560 


Lys Asp Thr Asp Asn Lys Ser Val Glu Asn Cys Val Cys Ile Met Arg 
                565                 570                 575     


Asn Leu Ser Tyr His Val His Lys Glu Val Pro Gly Ala Asp Arg Tyr 
            580                 585                 590         


Gln Glu Ala Glu Pro Gly Pro Leu Gly Ser Ala Val Gly Ser Gln Arg 
        595                 600                 605             


Arg Arg Arg Asp Asp Ala Ser Cys Phe Gly Gly Lys Lys Ala Lys Glu 
    610                 615                 620                 


Glu Trp Phe His Gln Gly Lys Lys Asp Gly Glu Met Asp Arg Asn Phe 
625                 630                 635                 640 


Asp Thr Leu Asp Leu Pro Lys Arg Thr Glu Ala Ala Lys Gly Phe Glu 
                645                 650                 655     


Leu Leu Tyr Gln Pro Glu Val Val Arg Leu Tyr Leu Ser Leu Leu Thr 
            660                 665                 670         


Glu Ser Arg Asn Phe Asn Thr Leu Glu Ala Ala Ala Gly Ala Leu Gln 
        675                 680                 685             


Asn Leu Ser Ala Gly Asn Trp Met Trp Ala Thr Tyr Ile Arg Ala Thr 
    690                 695                 700                 


Val Arg Lys Glu Arg Gly Leu Pro Val Leu Val Glu Leu Leu Gln Ser 
705                 710                 715                 720 


Glu Thr Asp Lys Val Val Arg Ala Val Ala Ile Ala Leu Arg Asn Leu 
                725                 730                 735     


Ser Leu Asp Arg Arg Asn Lys Asp Leu Ile Gly Ser Tyr Ala Met Ala 
            740                 745                 750         


Glu Leu Val Arg Asn Val Arg Asn Ala Gln Ala Pro Pro Arg Pro Gly 
        755                 760                 765             


Ala Cys Leu Glu Glu Asp Thr Val Val Ala Val Leu Asn Thr Ile His 
    770                 775                 780                 


Glu Ile Val Ser Asp Ser Leu Asp Asn Ala Arg Ser Leu Leu Gln Ala 
785                 790                 795                 800 


Arg Gly Val Pro Ala Leu Val Ala Leu Val Ala Ser Ser Gln Ser Val 
                805                 810                 815     


Arg Glu Ala Lys Ala Ala Ser His Val Leu Gln Thr Val Trp Ser Tyr 
            820                 825                 830         


Lys Glu Leu Arg Gly Thr Leu Gln Lys Asp Gly Trp Thr Lys Ala Arg 
        835                 840                 845             


Phe Gln Ser Ala Ala Ala Thr Ala Lys Gly Pro Lys Gly Ala Leu Ser 
    850                 855                 860                 


Pro Gly Gly Phe Asp Asp Ser Thr Leu Pro Leu Val Asp Lys Ser Leu 
865                 870                 875                 880 


Glu Gly Glu Lys Thr Gly Ser Arg Asp Val Ile Pro Met Asp Ala Leu 
                885                 890                 895     


Gly Pro Asp Gly Tyr Ser Thr Val Asp Arg Arg Glu Arg Arg Pro Arg 
            900                 905                 910         


Gly Ala Ser Ser Ala Gly Glu Ala Ser Glu Lys Glu Pro Leu Lys Leu 
        915                 920                 925             


Asp Pro Ser Arg Lys Ala Pro Pro Pro Gly Pro Ser Arg Pro Ala Val 
    930                 935                 940                 


Arg Leu Val Asp Ala Val Gly Asp Ala Lys Pro Gln Pro Val Asp Ser 
945                 950                 955                 960 


Trp Val 
        


<210>  1283
<211>  308
<212>  PRT
<213>  Human

<400>  1283

Met Asn Pro Ile Val Val Val His Gly Gly Gly Ala Gly Pro Ile Ser 
1               5                   10                  15      


Lys Asp Arg Lys Glu Arg Val His Gln Gly Met Val Arg Ala Ala Thr 
            20                  25                  30          


Val Gly Tyr Gly Ile Leu Arg Glu Gly Gly Ser Ala Val Asp Ala Val 
        35                  40                  45              


Glu Gly Ala Val Val Ala Leu Glu Asp Asp Pro Glu Phe Asn Ala Gly 
    50                  55                  60                  


Cys Gly Ser Val Leu Asn Thr Asn Gly Glu Val Glu Met Asp Ala Ser 
65                  70                  75                  80  


Ile Met Asp Gly Lys Asp Leu Ser Ala Gly Ala Val Ser Ala Val Gln 
                85                  90                  95      


Cys Ile Ala Asn Pro Ile Lys Leu Ala Arg Leu Val Met Glu Lys Thr 
            100                 105                 110         


Pro His Cys Phe Leu Thr Asp Gln Gly Ala Ala Gln Phe Ala Ala Ala 
        115                 120                 125             


Met Gly Val Pro Glu Ile Pro Gly Glu Lys Leu Val Thr Glu Arg Asn 
    130                 135                 140                 


Lys Lys Arg Leu Glu Lys Glu Lys His Glu Lys Gly Ala Gln Lys Thr 
145                 150                 155                 160 


Asp Cys Gln Lys Asn Leu Gly Thr Val Gly Ala Val Ala Leu Asp Cys 
                165                 170                 175     


Lys Gly Asn Val Ala Tyr Ala Thr Ser Thr Gly Gly Ile Val Asn Lys 
            180                 185                 190         


Met Val Gly Arg Val Gly Asp Ser Pro Cys Leu Gly Ala Gly Gly Tyr 
        195                 200                 205             


Ala Asp Asn Asp Ile Gly Ala Val Ser Thr Thr Gly His Gly Glu Ser 
    210                 215                 220                 


Ile Leu Lys Val Asn Leu Ala Arg Leu Thr Leu Phe His Ile Glu Gln 
225                 230                 235                 240 


Gly Lys Thr Val Glu Glu Ala Ala Asp Leu Ser Leu Gly Tyr Met Lys 
                245                 250                 255     


Ser Arg Val Lys Gly Leu Gly Gly Leu Ile Val Val Ser Lys Thr Gly 
            260                 265                 270         


Asp Trp Val Ala Lys Trp Thr Ser Thr Ser Met Pro Trp Ala Ala Ala 
        275                 280                 285             


Lys Asp Gly Lys Leu His Phe Gly Ile Asp Pro Asp Asp Thr Thr Ile 
    290                 295                 300                 


Thr Asp Leu Pro 
305             


<210>  1284
<211>  213
<212>  PRT
<213>  Human

<400>  1284

Met Ala Ala Pro Ala Val Ser Gly Leu Ser Arg Gln Val Arg Cys Phe 
1               5                   10                  15      


Ser Thr Ser Val Val Arg Pro Phe Ala Lys Leu Val Arg Pro Pro Val 
            20                  25                  30          


Gln Val Tyr Gly Ile Glu Gly Arg Tyr Ala Thr Ala Leu Tyr Ser Ala 
        35                  40                  45              


Ala Ser Lys Gln Asn Lys Leu Glu Gln Val Glu Lys Glu Leu Leu Arg 
    50                  55                  60                  


Val Ala Gln Ile Leu Lys Glu Pro Lys Val Ala Ala Ser Val Leu Asn 
65                  70                  75                  80  


Pro Tyr Val Lys Arg Ser Ile Lys Val Lys Ser Leu Asn Asp Ile Thr 
                85                  90                  95      


Ala Lys Glu Arg Phe Ser Pro Leu Thr Thr Asn Leu Ile Asn Leu Leu 
            100                 105                 110         


Ala Glu Asn Gly Arg Leu Ser Asn Thr Gln Gly Val Val Ser Ala Phe 
        115                 120                 125             


Ser Thr Met Met Ser Val His Arg Gly Glu Val Pro Cys Thr Val Thr 
    130                 135                 140                 


Ser Ala Ser Pro Leu Glu Glu Ala Thr Leu Ser Glu Leu Lys Thr Val 
145                 150                 155                 160 


Leu Lys Ser Phe Leu Ser Gln Gly Gln Val Leu Lys Leu Glu Ala Lys 
                165                 170                 175     


Thr Asp Pro Ser Ile Leu Gly Gly Met Ile Val Arg Ile Gly Glu Lys 
            180                 185                 190         


Tyr Val Asp Met Ser Val Lys Thr Lys Ile Gln Lys Leu Gly Arg Ala 
        195                 200                 205             


Met Arg Glu Ile Val 
    210             


<210>  1285
<211>  145
<212>  PRT
<213>  Human

<400>  1285

Met Gly Cys Gly Gly Ser Arg Ala Asp Ala Ile Glu Pro Arg Tyr Tyr 
1               5                   10                  15      


Glu Ser Trp Thr Arg Glu Thr Glu Ser Thr Trp Leu Thr Tyr Thr Asp 
            20                  25                  30          


Ser Asp Ala Pro Pro Ser Ala Ala Ala Pro Asp Ser Gly Pro Glu Ala 
        35                  40                  45              


Gly Gly Leu His Ser Gly Met Leu Glu Asp Gly Leu Pro Ser Asn Gly 
    50                  55                  60                  


Val Pro Arg Ser Thr Ala Pro Gly Gly Ile Pro Asn Pro Glu Lys Lys 
65                  70                  75                  80  


Thr Asn Cys Glu Thr Gln Cys Pro Asn Pro Gln Ser Leu Ser Ser Gly 
                85                  90                  95      


Pro Leu Thr Gln Lys Gln Asn Gly Leu Gln Thr Thr Glu Ala Lys Arg 
            100                 105                 110         


Asp Ala Lys Arg Met Pro Ala Lys Glu Val Thr Ile Asn Val Thr Asp 
        115                 120                 125             


Ser Ile Gln Gln Met Asp Arg Ser Arg Arg Ile Thr Lys Asn Cys Val 
    130                 135                 140                 


Asn 
145 


<210>  1286
<211>  575
<212>  PRT
<213>  Human

<400>  1286

Met Ser Ala Ala Thr His Ser Pro Met Met Gln Val Ala Ser Gly Asn 
1               5                   10                  15      


Gly Asp Arg Asp Pro Leu Pro Pro Gly Trp Glu Ile Lys Ile Asp Pro 
            20                  25                  30          


Gln Thr Gly Trp Pro Phe Phe Val Asp His Asn Ser Arg Thr Thr Thr 
        35                  40                  45              


Trp Asn Asp Pro Arg Val Pro Ser Glu Gly Pro Lys Glu Thr Pro Ser 
    50                  55                  60                  


Ser Ala Asn Gly Pro Ser Arg Glu Gly Ser Arg Leu Pro Pro Ala Arg 
65                  70                  75                  80  


Glu Gly His Pro Val Tyr Pro Gln Leu Arg Pro Gly Tyr Ile Pro Ile 
                85                  90                  95      


Pro Val Leu His Glu Gly Ala Glu Asn Arg Gln Val His Pro Phe His 
            100                 105                 110         


Val Tyr Pro Gln Pro Gly Met Gln Arg Phe Arg Thr Glu Ala Ala Ala 
        115                 120                 125             


Ala Ala Pro Gln Arg Ser Gln Ser Pro Leu Arg Gly Met Pro Glu Thr 
    130                 135                 140                 


Thr Gln Pro Asp Lys Gln Cys Gly Gln Val Ala Ala Ala Ala Ala Ala 
145                 150                 155                 160 


Gln Pro Pro Ala Ser His Gly Pro Glu Arg Ser Gln Ser Pro Ala Ala 
                165                 170                 175     


Ser Asp Cys Ser Ser Ser Ser Ser Ser Ala Ser Leu Pro Ser Ser Gly 
            180                 185                 190         


Arg Ser Ser Leu Gly Ser His Gln Leu Pro Arg Gly Tyr Ile Ser Ile 
        195                 200                 205             


Pro Val Ile His Glu Gln Asn Val Thr Arg Pro Ala Ala Gln Pro Ser 
    210                 215                 220                 


Phe His Gln Ala Gln Lys Thr His Tyr Pro Ala Gln Gln Gly Glu Tyr 
225                 230                 235                 240 


Gln Thr His Gln Pro Val Tyr His Lys Ile Gln Gly Asp Asp Trp Glu 
                245                 250                 255     


Pro Arg Pro Leu Arg Ala Ala Ser Pro Phe Arg Ser Ser Val Gln Gly 
            260                 265                 270         


Ala Ser Ser Arg Glu Gly Ser Pro Ala Arg Ser Ser Thr Pro Leu His 
        275                 280                 285             


Ser Pro Ser Pro Ile Arg Val His Thr Val Val Asp Arg Pro Gln Gln 
    290                 295                 300                 


Pro Met Thr His Arg Glu Thr Ala Pro Val Ser Gln Pro Glu Asn Lys 
305                 310                 315                 320 


Pro Glu Ser Lys Pro Gly Pro Val Gly Pro Glu Leu Pro Pro Gly His 
                325                 330                 335     


Ile Pro Ile Gln Val Ile Arg Lys Glu Val Asp Ser Lys Pro Val Ser 
            340                 345                 350         


Gln Lys Pro Pro Pro Pro Ser Glu Lys Val Glu Val Lys Val Pro Pro 
        355                 360                 365             


Ala Pro Val Pro Cys Pro Pro Pro Ser Pro Gly Pro Ser Ala Val Pro 
    370                 375                 380                 


Ser Ser Pro Lys Ser Val Ala Thr Glu Glu Arg Ala Ala Pro Ser Thr 
385                 390                 395                 400 


Ala Pro Ala Glu Ala Thr Pro Pro Lys Pro Gly Glu Ala Glu Ala Pro 
                405                 410                 415     


Pro Lys His Pro Gly Val Leu Lys Val Glu Ala Ile Leu Glu Lys Val 
            420                 425                 430         


Gln Gly Leu Glu Gln Ala Val Asp Asn Phe Glu Gly Lys Lys Thr Asp 
        435                 440                 445             


Lys Lys Tyr Leu Met Ile Glu Glu Tyr Leu Thr Lys Glu Leu Leu Ala 
    450                 455                 460                 


Leu Asp Ser Val Asp Pro Glu Gly Arg Ala Asp Val Arg Gln Ala Arg 
465                 470                 475                 480 


Arg Asp Gly Val Arg Lys Val Gln Thr Ile Leu Glu Lys Leu Glu Gln 
                485                 490                 495     


Lys Ala Ile Asp Val Pro Gly Gln Val Gln Val Tyr Glu Leu Gln Pro 
            500                 505                 510         


Ser Asn Leu Glu Ala Asp Gln Pro Leu Gln Ala Ile Met Glu Met Gly 
        515                 520                 525             


Ala Val Ala Ala Asp Lys Gly Lys Lys Asn Ala Gly Asn Ala Glu Asp 
    530                 535                 540                 


Pro His Thr Glu Thr Gln Gln Pro Glu Ala Thr Ala Ala Ala Thr Ser 
545                 550                 555                 560 


Asn Pro Ser Ser Met Thr Asp Thr Pro Gly Asn Pro Ala Ala Pro 
                565                 570                 575 


<210>  1287
<211>  202
<212>  PRT
<213>  Human

<400>  1287

Met Ser Gly Arg Ser Val Arg Ala Glu Thr Arg Ser Arg Ala Lys Asp 
1               5                   10                  15      


Asp Ile Lys Lys Val Met Ala Ala Ile Glu Lys Val Arg Lys Trp Glu 
            20                  25                  30          


Lys Lys Trp Val Thr Val Gly Asp Thr Ser Leu Arg Ile Phe Lys Trp 
        35                  40                  45              


Val Pro Val Thr Asp Ser Lys Glu Lys Glu Lys Ser Lys Ser Asn Ser 
    50                  55                  60                  


Ser Ala Ala Arg Glu Pro Asn Gly Phe Pro Ser Asp Ala Ser Ala Asn 
65                  70                  75                  80  


Ser Ser Leu Leu Leu Glu Phe Gln Asp Glu Asn Ser Asn Gln Ser Ser 
                85                  90                  95      


Val Ser Asp Val Tyr Gln Leu Lys Val Asp Ser Ser Thr Asn Ser Ser 
            100                 105                 110         


Pro Ser Pro Gln Gln Ser Glu Ser Leu Ser Pro Ala His Thr Ser Asp 
        115                 120                 125             


Phe Arg Thr Asp Asp Ser Gln Pro Pro Thr Leu Gly Gln Glu Ile Leu 
    130                 135                 140                 


Glu Glu Pro Ser Leu Pro Ser Ser Glu Val Ala Asp Glu Pro Pro Thr 
145                 150                 155                 160 


Leu Thr Lys Glu Glu Pro Val Pro Leu Glu Thr Gln Val Val Glu Glu 
                165                 170                 175     


Glu Glu Asp Ser Gly Ala Pro Pro Leu Lys Arg Phe Cys Val Asp Gln 
            180                 185                 190         


Pro Thr Val Pro Gln Thr Ala Ser Glu Ser 
        195                 200         


<210>  1288
<211>  353
<212>  PRT
<213>  Human

<400>  1288

Met Gly Thr Pro Ser Gly Thr Ala Glu Pro Tyr Asp Gly Thr Lys Ala 
1               5                   10                  15      


Arg Leu Tyr Ser Leu Gln Ser Asp Pro Ala Thr Tyr Cys Asn Glu Pro 
            20                  25                  30          


Asp Gly Pro Pro Glu Leu Phe Asp Ala Trp Leu Ser Gln Phe Cys Leu 
        35                  40                  45              


Glu Glu Lys Lys Gly Glu Ile Ser Glu Leu Leu Val Gly Ser Pro Ser 
    50                  55                  60                  


Ile Arg Ala Leu Tyr Thr Lys Met Val Pro Ala Ala Val Ser His Ser 
65                  70                  75                  80  


Glu Phe Trp His Arg Tyr Phe Tyr Lys Val His Gln Leu Glu Gln Glu 
                85                  90                  95      


Gln Ala Arg Arg Asp Ala Leu Lys Gln Arg Ala Glu Gln Ser Ile Ser 
            100                 105                 110         


Glu Glu Pro Gly Trp Glu Glu Glu Glu Glu Glu Leu Met Gly Ile Ser 
        115                 120                 125             


Pro Ile Ser Pro Lys Glu Ala Lys Val Pro Val Ala Lys Ile Ser Thr 
    130                 135                 140                 


Phe Pro Glu Gly Glu Pro Gly Pro Gln Ser Pro Cys Glu Glu Asn Leu 
145                 150                 155                 160 


Val Thr Ser Val Glu Pro Pro Ala Glu Val Thr Pro Ser Glu Ser Ser 
                165                 170                 175     


Glu Ser Ile Ser Leu Val Thr Gln Ile Ala Asn Pro Ala Thr Ala Pro 
            180                 185                 190         


Glu Ala Arg Val Leu Pro Lys Asp Leu Ser Gln Lys Leu Leu Glu Ala 
        195                 200                 205             


Ser Leu Glu Glu Gln Gly Leu Ala Val Asp Val Gly Glu Thr Gly Pro 
    210                 215                 220                 


Ser Pro Pro Ile His Ser Lys Pro Leu Thr Pro Ala Gly His Thr Gly 
225                 230                 235                 240 


Gly Pro Glu Pro Arg Pro Pro Ala Arg Val Glu Thr Leu Arg Glu Glu 
                245                 250                 255     


Ala Pro Thr Asp Leu Arg Val Phe Glu Leu Asn Ser Asp Ser Gly Lys 
            260                 265                 270         


Ser Thr Pro Ser Asn Asn Gly Lys Lys Gly Ser Ser Thr Asp Ile Ser 
        275                 280                 285             


Glu Asp Trp Glu Lys Asp Phe Asp Leu Asp Met Thr Glu Glu Glu Val 
    290                 295                 300                 


Gln Met Ala Leu Ser Lys Val Asp Ala Ser Gly Glu Val Ser Gly Pro 
305                 310                 315                 320 


Gly Gly Ser Glu Gly Ser Glu Pro Asn Gly Pro Gly Cys Glu Ser Ser 
                325                 330                 335     


Pro Gln Pro Ala Gln Leu Ser Pro Gln Glu Gly Pro Cys Ser Cys Leu 
            340                 345                 350         


Arg 
    


<210>  1289
<211>  492
<212>  PRT
<213>  Human

<400>  1289

Met Asn Arg Ile Arg Ile His Val Leu Pro Thr Asn Arg Gly Arg Ile 
1               5                   10                  15      


Thr Pro Val Pro Arg Ser Gln Glu Pro Leu Ser Cys Ala Phe Thr His 
            20                  25                  30          


Arg Pro Cys Ser His Pro Arg Leu Glu Gly Gln Glu Phe Cys Ile Lys 
        35                  40                  45              


His Ile Leu Glu Asp Lys Asn Ala Pro Phe Lys Gln Cys Ser Tyr Ile 
    50                  55                  60                  


Ser Thr Lys Asn Gly Lys Arg Cys Pro Asn Ala Ala Pro Lys Pro Glu 
65                  70                  75                  80  


Lys Lys Asp Gly Val Ser Phe Cys Ala Glu His Val Arg Arg Asn Ala 
                85                  90                  95      


Leu Ala Leu His Ala Gln Met Lys Lys Thr Asn Pro Gly Pro Val Gly 
            100                 105                 110         


Glu Thr Leu Leu Cys Gln Leu Ser Ser Tyr Ala Lys Thr Glu Leu Gly 
        115                 120                 125             


Ser Gln Thr Pro Glu Ser Ser Arg Ser Glu Ala Ser Arg Ile Leu Asp 
    130                 135                 140                 


Glu Asp Ser Trp Ser Asp Gly Glu Gln Glu Pro Ile Thr Val Asp Gln 
145                 150                 155                 160 


Thr Trp Arg Gly Asp Pro Asp Ser Glu Ala Asp Ser Ile Asp Ser Asp 
                165                 170                 175     


Gln Glu Asp Pro Leu Lys His Ala Gly Val Tyr Thr Ala Glu Glu Val 
            180                 185                 190         


Ala Leu Ile Met Arg Glu Lys Leu Ile Arg Leu Gln Ser Leu Tyr Ile 
        195                 200                 205             


Asp Gln Phe Lys Arg Leu Gln His Leu Leu Lys Glu Lys Lys Arg Arg 
    210                 215                 220                 


Tyr Leu His Asn Arg Lys Val Glu His Glu Ala Leu Gly Ser Ser Leu 
225                 230                 235                 240 


Leu Thr Gly Pro Glu Gly Leu Leu Ala Lys Glu Arg Glu Asn Leu Lys 
                245                 250                 255     


Arg Leu Lys Cys Leu Arg Arg Tyr Arg Gln Arg Tyr Gly Val Glu Ala 
            260                 265                 270         


Leu Leu His Arg Gln Leu Lys Glu Arg Arg Met Leu Ala Thr Asp Gly 
        275                 280                 285             


Ala Ala Gln Gln Ala His Thr Thr Arg Ser Ser Gln Arg Cys Leu Ala 
    290                 295                 300                 


Phe Val Asp Asp Val Arg Cys Ser Asn Gln Ser Leu Pro Met Thr Arg 
305                 310                 315                 320 


His Cys Leu Thr His Ile Cys Gln Asp Thr Asn Gln Val Leu Phe Lys 
                325                 330                 335     


Cys Cys Gln Gly Ser Glu Glu Val Pro Cys Asn Lys Pro Val Pro Val 
            340                 345                 350         


Ser Leu Ser Glu Asp Pro Cys Cys Pro Leu His Phe Gln Leu Pro Pro 
        355                 360                 365             


Gln Met Tyr Lys Pro Glu Gln Val Leu Ser Val Pro Asp Asp Leu Glu 
    370                 375                 380                 


Ala Gly Pro Met Asp Leu Tyr Leu Ser Ala Ala Glu Leu Gln Pro Thr 
385                 390                 395                 400 


Glu Ser Leu Pro Leu Glu Phe Ser Asp Asp Leu Asp Val Val Gly Asp 
                405                 410                 415     


Gly Met Gln Cys Pro Pro Ser Pro Leu Leu Phe Asp Pro Ser Leu Thr 
            420                 425                 430         


Leu Glu Asp His Leu Val Lys Glu Ile Ala Glu Asp Pro Val Asp Ile 
        435                 440                 445             


Leu Gly Gln Met Gln Met Ala Gly Asp Gly Cys Arg Ser Gln Gly Ser 
    450                 455                 460                 


Arg Asn Ser Glu Lys Ala Ser Ala Pro Leu Ser Gln Ser Gly Leu Ala 
465                 470                 475                 480 


Thr Ala Asn Gly Lys Pro Glu Pro Thr Ser Ile Ser 
                485                 490         


<210>  1290
<211>  201
<212>  PRT
<213>  Human

<400>  1290

Met Ile Thr Glu Thr Ala Ala Glu Pro Thr Val Pro Ala Val Pro Ala 
1               5                   10                  15      


Ala Glu Glu Ala Thr Glu Ala Arg Gly Arg Glu Glu Pro Ala Trp Pro 
            20                  25                  30          


Trp Lys Asp Ala Pro Ile Arg Thr Leu Val Gln Arg Ile His Gln Leu 
        35                  40                  45              


Gln Ala Glu Arg Ala Gln Gly Phe Arg Arg Leu Glu Glu Trp Leu Ala 
    50                  55                  60                  


Pro Val Gln Gly Leu Arg Ala Trp Gly Arg Gly Leu Arg Val Pro Thr 
65                  70                  75                  80  


Cys Arg Arg Gly His Arg Gln Tyr Leu Arg Ser Gly Pro Asp Tyr Asp 
                85                  90                  95      


Phe Ala Arg Tyr Arg Ser Thr Val His Gly Val Thr Gln Ala Phe Ala 
            100                 105                 110         


Ala Ala Ser Arg Glu Val Leu Ala Val Glu Ala Glu Leu Gly Gly Pro 
        115                 120                 125             


Arg Arg Gln Pro Leu Leu Ala Gly His Val Arg Ser Leu Gln Glu Leu 
    130                 135                 140                 


Glu Gln Thr Arg Leu Gly Thr Val Ala Leu Leu Gln Leu Met Glu Thr 
145                 150                 155                 160 


Pro Glu Leu Ala Gly Gln Glu Asp Ala Val Arg Met Gln Gln Leu Lys 
                165                 170                 175     


Met Lys Val Ile Lys Thr Met Glu Ala Ile Ser Glu Val Leu Gln Asp 
            180                 185                 190         


Leu Arg Phe Asp Ala Glu Ser Ala Glu 
        195                 200     


<210>  1291
<211>  171
<212>  PRT
<213>  Human

<400>  1291

Met Trp Thr Leu Lys Ser Ser Leu Val Leu Leu Leu Cys Leu Thr Cys 
1               5                   10                  15      


Ser Tyr Ala Phe Met Phe Ser Ser Leu Arg Gln Lys Thr Ser Glu Pro 
            20                  25                  30          


Gln Gly Lys Val Pro Cys Gly Glu His Phe Arg Ile Arg Gln Asn Leu 
        35                  40                  45              


Pro Glu His Thr Gln Gly Trp Leu Gly Ser Lys Trp Leu Trp Leu Leu 
    50                  55                  60                  


Phe Ala Val Val Pro Phe Val Ile Leu Gln Cys Gln Arg Asp Ser Glu 
65                  70                  75                  80  


Lys Asn Lys Glu Gln Ser Pro Pro Gly Leu Arg Gly Phe Pro Phe Arg 
                85                  90                  95      


Thr Pro Leu Lys Lys Asn Gln Asn Ala Ser Leu Tyr Lys Asp Cys Val 
            100                 105                 110         


Phe Asn Thr Leu Asn Glu Leu Glu Val Glu Leu Leu Lys Phe Val Ser 
        115                 120                 125             


Glu Val Gln Asn Leu Lys Gly Ala Met Ala Thr Gly Ser Gly Ser Asn 
    130                 135                 140                 


Leu Lys Leu Arg Arg Ser Glu Met Pro Ala Asp Pro Tyr His Val Thr 
145                 150                 155                 160 


Ile Cys Lys Ile Trp Gly Glu Glu Ser Ser Ser 
                165                 170     


<210>  1292
<211>  205
<212>  PRT
<213>  Human

<400>  1292

Met Ala Ala Arg Asp Ala Thr Ser Gly Ser Leu Ser Glu Glu Ser Ser 
1               5                   10                  15      


Ala Leu Asp Leu Pro Ser Ala Cys Asp Ile Arg Asp Tyr Val Leu Gln 
            20                  25                  30          


Gly Pro Ser Gln Glu Ala Asn Ser Glu Ala Phe Ser Ser Leu Glu Phe 
        35                  40                  45              


His Ser Phe Pro Tyr Ser Ser Asp Val Asp Pro Asp Thr Ser Asn Leu 
    50                  55                  60                  


Asn Ile Glu Gln Asn Asn Ser Trp Thr Ala Glu Asn Phe Trp Leu Asp 
65                  70                  75                  80  


Pro Ala Val Lys Gly Gln Ser Glu Lys Glu Glu Asp Asp Gly Leu Arg 
                85                  90                  95      


Lys Ser Leu Asp Arg Phe Tyr Glu Met Phe Gly His Pro Gln Pro Gly 
            100                 105                 110         


Ser Ala Asn Ser Leu Ser Ala Ser Val Cys Lys Cys Leu Ser Gln Lys 
        115                 120                 125             


Ile Thr Gln Leu Arg Gly Gln Glu Ser Gln Lys Tyr Ala Leu Arg Ser 
    130                 135                 140                 


Phe Gln Met Ala Arg Val Ile Phe Asn Arg Asp Gly Cys Ser Val Leu 
145                 150                 155                 160 


Gln Arg His Ser Arg Asp Thr His Phe Tyr Pro Leu Glu Glu Gly Ser 
                165                 170                 175     


Thr Ser Leu Asp Asp Glu Lys Pro Asn Pro Gly Leu Ser Lys Asp Ile 
            180                 185                 190         


Thr His Phe Leu Leu Gln Gln Asn Val Met Lys Asp Leu 
        195                 200                 205 


<210>  1293
<211>  306
<212>  PRT
<213>  Human

<400>  1293

Met Gly Cys Asp Gly Gly Thr Ile Pro Lys Arg His Glu Leu Val Lys 
1               5                   10                  15      


Gly Pro Lys Lys Val Glu Lys Val Asp Lys Asp Ala Glu Leu Val Ala 
            20                  25                  30          


Gln Trp Asn Tyr Cys Thr Leu Ser Gln Glu Ile Leu Arg Arg Pro Ile 
        35                  40                  45              


Val Ala Cys Glu Leu Gly Arg Leu Tyr Asn Lys Asp Ala Val Ile Glu 
    50                  55                  60                  


Phe Leu Leu Asp Lys Ser Ala Glu Lys Ala Leu Gly Lys Ala Ala Ser 
65                  70                  75                  80  


His Ile Lys Ser Ile Lys Asn Val Thr Glu Leu Lys Leu Ser Asp Asn 
                85                  90                  95      


Pro Ala Trp Glu Gly Asp Lys Gly Asn Thr Lys Gly Asp Lys His Asp 
            100                 105                 110         


Asp Leu Gln Arg Ala Arg Phe Ile Cys Pro Val Val Gly Leu Glu Met 
        115                 120                 125             


Asn Gly Arg His Arg Phe Cys Phe Leu Arg Cys Cys Gly Cys Val Phe 
    130                 135                 140                 


Ser Glu Arg Ala Leu Lys Glu Ile Lys Ala Glu Val Cys His Thr Cys 
145                 150                 155                 160 


Gly Ala Ala Phe Gln Glu Asp Asp Val Ile Met Leu Asn Gly Thr Lys 
                165                 170                 175     


Glu Asp Val Asp Val Leu Lys Thr Arg Met Glu Glu Arg Arg Leu Arg 
            180                 185                 190         


Ala Lys Leu Glu Lys Lys Thr Lys Lys Pro Lys Ala Ala Glu Ser Val 
        195                 200                 205             


Ser Lys Pro Asp Val Ser Glu Glu Ala Pro Gly Pro Ser Lys Val Lys 
    210                 215                 220                 


Thr Gly Lys Pro Glu Glu Ala Ser Leu Asp Ser Arg Glu Lys Lys Thr 
225                 230                 235                 240 


Asn Leu Ala Pro Lys Ser Thr Ala Met Asn Glu Ser Ser Ser Gly Lys 
                245                 250                 255     


Ala Gly Lys Pro Pro Cys Gly Ala Thr Lys Arg Ser Ile Ala Asp Ser 
            260                 265                 270         


Glu Glu Ser Glu Ala Tyr Lys Ser Leu Phe Thr Thr His Ser Ser Ala 
        275                 280                 285             


Lys Arg Ser Lys Glu Glu Ser Ala His Trp Val Thr His Thr Ser Tyr 
    290                 295                 300                 


Cys Phe 
305     


<210>  1294
<211>  729
<212>  PRT
<213>  Human

<400>  1294

Met Phe Ser Ala Leu Lys Lys Leu Val Gly Ser Asp Gln Ala Pro Gly 
1               5                   10                  15      


Arg Asp Lys Asn Ile Pro Ala Gly Leu Gln Ser Met Asn Gln Ala Leu 
            20                  25                  30          


Gln Arg Arg Phe Ala Lys Gly Val Gln Tyr Asn Met Lys Ile Val Ile 
        35                  40                  45              


Arg Gly Asp Arg Asn Thr Gly Lys Thr Ala Leu Trp His Arg Leu Gln 
    50                  55                  60                  


Gly Arg Pro Phe Val Glu Glu Tyr Ile Pro Thr Gln Glu Ile Gln Val 
65                  70                  75                  80  


Thr Ser Ile His Trp Ser Tyr Lys Thr Thr Asp Asp Ile Val Lys Val 
                85                  90                  95      


Glu Val Trp Asp Val Val Asp Lys Gly Lys Cys Lys Lys Arg Gly Asp 
            100                 105                 110         


Gly Leu Lys Met Glu Asn Asp Pro Gln Glu Ala Glu Ser Glu Met Ala 
        115                 120                 125             


Leu Asp Ala Glu Phe Leu Asp Val Tyr Lys Asn Cys Asn Gly Val Val 
    130                 135                 140                 


Met Met Phe Asp Ile Thr Lys Gln Trp Thr Phe Asn Tyr Ile Leu Arg 
145                 150                 155                 160 


Glu Leu Pro Lys Val Pro Thr His Val Pro Val Cys Val Leu Gly Asn 
                165                 170                 175     


Tyr Arg Asp Met Gly Glu His Arg Val Ile Leu Pro Asp Asp Val Arg 
            180                 185                 190         


Asp Phe Ile Asp Asn Leu Asp Arg Pro Pro Gly Ser Ser Tyr Phe Arg 
        195                 200                 205             


Tyr Ala Glu Ser Ser Met Lys Asn Ser Phe Gly Leu Lys Tyr Leu His 
    210                 215                 220                 


Lys Phe Phe Asn Ile Pro Phe Leu Gln Leu Gln Arg Glu Thr Leu Leu 
225                 230                 235                 240 


Arg Gln Leu Glu Thr Asn Gln Leu Asp Met Asp Ala Thr Leu Glu Glu 
                245                 250                 255     


Leu Ser Val Gln Gln Glu Thr Glu Asp Gln Asn Tyr Gly Ile Phe Leu 
            260                 265                 270         


Glu Met Met Glu Ala Arg Ser Arg Gly His Ala Ser Pro Leu Ala Ala 
        275                 280                 285             


Asn Gly Gln Ser Pro Ser Pro Gly Ser Gln Ser Pro Val Val Pro Ala 
    290                 295                 300                 


Gly Ala Val Ser Thr Gly Ser Ser Ser Pro Gly Thr Pro Gln Pro Ala 
305                 310                 315                 320 


Pro Gln Leu Pro Leu Asn Ala Ala Pro Pro Ser Ser Val Pro Pro Val 
                325                 330                 335     


Pro Pro Ser Glu Ala Leu Pro Pro Pro Ala Cys Pro Ser Ala Pro Ala 
            340                 345                 350         


Pro Arg Arg Ser Ile Ile Ser Arg Leu Phe Gly Thr Ser Pro Ala Thr 
        355                 360                 365             


Glu Ala Ala Pro Pro Pro Pro Glu Pro Val Pro Ala Ala Glu Gly Pro 
    370                 375                 380                 


Ala Thr Val Gln Ser Val Glu Asp Phe Val Pro Asp Asp Arg Leu Asp 
385                 390                 395                 400 


Arg Ser Phe Leu Glu Asp Thr Thr Pro Ala Arg Asp Glu Lys Lys Val 
                405                 410                 415     


Gly Ala Lys Ala Ala Gln Gln Asp Ser Asp Ser Asp Gly Glu Ala Leu 
            420                 425                 430         


Gly Gly Asn Pro Met Val Ala Gly Phe Gln Asp Asp Val Asp Leu Glu 
        435                 440                 445             


Asp Gln Pro Arg Gly Ser Pro Pro Leu Pro Ala Gly Pro Val Pro Ser 
    450                 455                 460                 


Gln Asp Ile Thr Leu Ser Ser Glu Glu Glu Ala Glu Val Ala Ala Pro 
465                 470                 475                 480 


Thr Lys Gly Pro Ala Pro Ala Pro Gln Gln Cys Ser Glu Pro Glu Thr 
                485                 490                 495     


Lys Trp Ser Ser Ile Pro Ala Ser Lys Pro Arg Arg Gly Thr Ala Pro 
            500                 505                 510         


Thr Arg Thr Ala Ala Pro Pro Trp Pro Gly Gly Val Ser Val Arg Thr 
        515                 520                 525             


Gly Pro Glu Lys Arg Ser Ser Thr Arg Pro Pro Ala Glu Met Glu Pro 
    530                 535                 540                 


Gly Lys Gly Glu Gln Ala Ser Ser Ser Glu Ser Asp Pro Glu Gly Pro 
545                 550                 555                 560 


Ile Ala Ala Gln Met Leu Ser Phe Val Met Asp Asp Pro Asp Phe Glu 
                565                 570                 575     


Ser Glu Gly Ser Asp Thr Gln Arg Arg Ala Asp Asp Phe Pro Val Arg 
            580                 585                 590         


Asp Asp Pro Ser Asp Val Thr Asp Glu Asp Glu Gly Pro Ala Glu Pro 
        595                 600                 605             


Pro Pro Pro Pro Lys Leu Pro Leu Pro Ala Phe Arg Leu Lys Asn Asp 
    610                 615                 620                 


Ser Asp Leu Phe Gly Leu Gly Leu Glu Glu Ala Gly Pro Lys Glu Ser 
625                 630                 635                 640 


Ser Glu Glu Gly Lys Glu Gly Lys Thr Pro Ser Lys Glu Lys Lys Lys 
                645                 650                 655     


Lys Lys Lys Lys Gly Lys Glu Glu Glu Glu Lys Ala Ala Lys Lys Lys 
            660                 665                 670         


Ser Lys His Lys Lys Ser Lys Asp Lys Glu Glu Gly Lys Glu Glu Arg 
        675                 680                 685             


Arg Arg Arg Gln Gln Arg Pro Pro Arg Ser Arg Glu Arg Thr Ala Ala 
    690                 695                 700                 


Asp Glu Leu Glu Ala Phe Leu Gly Gly Gly Ala Pro Gly Gly Arg His 
705                 710                 715                 720 


Pro Gly Gly Gly Asp Tyr Glu Glu Leu 
                725                 


<210>  1295
<211>  2220
<212>  PRT
<213>  Human

<400>  1295

Met Ile Arg Ile Ala Ala Leu Asn Ala Ser Ser Thr Ile Glu Asp Asp 
1               5                   10                  15      


His Glu Gly Ser Phe Lys Ser His Lys Thr Gln Thr Lys Glu Ala Gln 
            20                  25                  30          


Glu Ala Glu Ala Phe Ala Leu Tyr His Lys Ala Leu Asp Leu Gln Lys 
        35                  40                  45              


His Asp Arg Phe Glu Glu Ser Ala Lys Ala Tyr His Glu Leu Leu Glu 
    50                  55                  60                  


Ala Ser Leu Leu Arg Glu Ala Val Ser Ser Gly Asp Glu Lys Glu Gly 
65                  70                  75                  80  


Leu Lys His Pro Gly Leu Ile Leu Lys Tyr Ser Thr Tyr Lys Asn Leu 
                85                  90                  95      


Ala Gln Leu Ala Ala Gln Arg Glu Asp Leu Glu Thr Ala Met Glu Phe 
            100                 105                 110         


Tyr Leu Glu Ala Val Met Leu Asp Ser Thr Asp Val Asn Leu Trp Tyr 
        115                 120                 125             


Lys Ile Gly His Val Ala Leu Arg Leu Ile Arg Ile Pro Leu Ala Arg 
    130                 135                 140                 


His Ala Phe Glu Glu Gly Leu Arg Cys Asn Pro Asp His Trp Pro Cys 
145                 150                 155                 160 


Leu Asp Asn Leu Ile Thr Val Leu Tyr Thr Leu Ser Asp Tyr Thr Thr 
                165                 170                 175     


Cys Leu Tyr Phe Ile Cys Lys Ala Leu Glu Lys Asp Cys Arg Tyr Ser 
            180                 185                 190         


Lys Gly Leu Val Leu Lys Glu Lys Ile Phe Glu Glu Gln Pro Cys Leu 
        195                 200                 205             


Arg Lys Asp Ser Leu Arg Met Phe Leu Lys Cys Asp Met Ser Ile His 
    210                 215                 220                 


Asp Val Ser Val Ser Ala Ala Glu Thr Gln Ala Ile Val Asp Glu Ala 
225                 230                 235                 240 


Leu Gly Leu Arg Lys Lys Arg Gln Ala Leu Ile Val Arg Glu Lys Glu 
                245                 250                 255     


Pro Asp Leu Lys Leu Val Gln Pro Ile Pro Phe Phe Thr Trp Lys Cys 
            260                 265                 270         


Leu Gly Glu Ser Leu Leu Ala Met Tyr Asn His Leu Thr Thr Cys Glu 
        275                 280                 285             


Pro Pro Arg Pro Ser Leu Gly Lys Arg Ile Asp Leu Ser Asp Tyr Gln 
    290                 295                 300                 


Asp Pro Ser Gln Pro Leu Glu Ser Ser Met Val Val Thr Pro Val Asn 
305                 310                 315                 320 


Val Ile Gln Pro Ser Thr Val Ser Thr Asn Pro Ala Val Ala Val Ala 
                325                 330                 335     


Glu Pro Val Val Ser Tyr Thr Ser Val Ala Thr Thr Ser Phe Pro Leu 
            340                 345                 350         


His Ser Pro Gly Leu Leu Glu Thr Gly Ala Pro Val Gly Asp Ile Ser 
        355                 360                 365             


Gly Gly Asp Lys Ser Lys Lys Gly Val Lys Arg Lys Lys Ile Ser Glu 
    370                 375                 380                 


Glu Ser Gly Glu Thr Ala Lys Arg Arg Ser Ala Arg Val Arg Asn Thr 
385                 390                 395                 400 


Lys Cys Lys Lys Glu Glu Lys Val Asp Phe Gln Glu Leu Leu Met Lys 
                405                 410                 415     


Phe Leu Pro Ser Arg Leu Arg Lys Leu Asp Pro Glu Glu Glu Asp Asp 
            420                 425                 430         


Ser Phe Asn Asn Tyr Glu Val Gln Ser Glu Ala Lys Leu Glu Ser Phe 
        435                 440                 445             


Pro Ser Ile Gly Pro Gln Arg Leu Ser Phe Asp Ser Ala Thr Phe Met 
    450                 455                 460                 


Glu Ser Glu Lys Gln Asp Val His Glu Phe Leu Leu Glu Asn Leu Thr 
465                 470                 475                 480 


Asn Gly Gly Ile Leu Glu Leu Met Met Arg Tyr Leu Lys Ala Met Gly 
                485                 490                 495     


His Lys Phe Leu Val Arg Trp Pro Pro Gly Leu Ala Glu Val Val Leu 
            500                 505                 510         


Ser Val Tyr His Ser Trp Arg Arg His Ser Thr Ser Leu Pro Asn Pro 
        515                 520                 525             


Leu Leu Arg Asp Cys Ser Asn Lys His Ile Lys Asp Met Met Leu Met 
    530                 535                 540                 


Ser Leu Ser Cys Met Glu Leu Gln Leu Asp Gln Trp Leu Leu Thr Lys 
545                 550                 555                 560 


Gly Arg Ser Ser Ala Val Ser Pro Arg Asn Cys Pro Ala Gly Met Val 
                565                 570                 575     


Asn Gly Arg Phe Gly Pro Asp Phe Pro Gly Thr His Cys Leu Gly Asp 
            580                 585                 590         


Leu Leu Gln Leu Ser Phe Ala Ser Ser Gln Arg Asp Leu Phe Glu Asp 
        595                 600                 605             


Gly Trp Leu Glu Phe Val Val Arg Val Tyr Trp Leu Lys Ala Arg Phe 
    610                 615                 620                 


Leu Ala Leu Gln Gly Asp Met Glu Gln Ala Leu Glu Asn Tyr Asp Ile 
625                 630                 635                 640 


Cys Thr Glu Met Leu Gln Ser Ser Thr Ala Ile Gln Val Glu Ala Gly 
                645                 650                 655     


Ala Glu Arg Arg Asp Ile Val Ile Arg Leu Pro Asn Leu His Asn Asp 
            660                 665                 670         


Ser Val Val Ser Leu Glu Glu Ile Asp Lys Asn Leu Lys Ser Leu Glu 
        675                 680                 685             


Arg Cys Gln Ser Leu Glu Glu Ile Gln Arg Leu Tyr Glu Ala Gly Asp 
    690                 695                 700                 


Tyr Lys Ala Val Val His Leu Leu Arg Pro Thr Leu Cys Thr Ser Gly 
705                 710                 715                 720 


Phe Asp Arg Ala Lys His Leu Glu Phe Met Thr Ser Ile Pro Glu Arg 
                725                 730                 735     


Pro Ala Gln Leu Leu Leu Leu Gln Asp Ser Leu Leu Arg Leu Lys Asp 
            740                 745                 750         


Tyr Arg Gln Cys Phe Glu Cys Ser Asp Val Ala Leu Asn Glu Ala Val 
        755                 760                 765             


Gln Gln Met Val Asn Ser Gly Glu Ala Ala Ala Lys Glu Glu Trp Val 
    770                 775                 780                 


Ala Thr Val Thr Gln Leu Leu Met Gly Ile Glu Gln Ala Leu Ser Ala 
785                 790                 795                 800 


Asp Ser Ser Gly Ser Ile Leu Lys Val Ser Ser Ser Thr Thr Gly Leu 
                805                 810                 815     


Val Arg Leu Thr Asn Asn Leu Ile Gln Val Ile Asp Cys Ser Met Ala 
            820                 825                 830         


Val Gln Glu Glu Ala Lys Glu Pro His Val Ser Ser Val Leu Pro Trp 
        835                 840                 845             


Ile Ile Leu His Arg Ile Ile Trp Gln Glu Glu Asp Thr Phe His Ser 
    850                 855                 860                 


Leu Cys His Gln Gln Gln Leu Gln Asn Pro Ala Glu Glu Gly Met Ser 
865                 870                 875                 880 


Glu Thr Pro Met Leu Pro Ser Ser Leu Met Leu Leu Asn Thr Ala His 
                885                 890                 895     


Glu Tyr Leu Gly Arg Arg Ser Trp Cys Cys Asn Ser Asp Gly Ala Leu 
            900                 905                 910         


Leu Arg Phe Tyr Val Arg Val Leu Gln Lys Glu Leu Ala Ala Ser Thr 
        915                 920                 925             


Ser Glu Asp Thr His Pro Tyr Lys Glu Glu Leu Glu Thr Ala Leu Glu 
    930                 935                 940                 


Gln Cys Phe Tyr Cys Leu Tyr Ser Phe Pro Ser Lys Lys Ser Lys Ala 
945                 950                 955                 960 


Arg Tyr Leu Glu Glu His Ser Ala Gln Gln Val Asp Leu Ile Trp Glu 
                965                 970                 975     


Asp Ala Leu Phe Met Phe Glu Tyr Phe Lys Pro Lys Thr Leu Pro Glu 
            980                 985                 990         


Phe Asp Ser Tyr Lys Thr Ser Thr  Val Ser Ala Asp Leu  Ala Asn Leu 
        995                 1000                 1005             


Leu Lys  Arg Ile Ala Thr Ile  Val Pro Arg Thr Glu  Arg Pro Ala 
    1010                 1015                 1020             


Leu Ser  Leu Asp Lys Val Ser  Ala Tyr Ile Glu Gly  Thr Ser Thr 
    1025                 1030                 1035             


Glu Val  Pro Cys Leu Pro Glu  Gly Ala Asp Pro Ser  Pro Pro Val 
    1040                 1045                 1050             


Val Asn  Glu Leu Tyr Tyr Leu  Leu Ala Asp Tyr His  Phe Lys Asn 
    1055                 1060                 1065             


Lys Glu  Gln Ser Lys Ala Ile  Lys Phe Tyr Met His  Asp Ile Cys 
    1070                 1075                 1080             


Ile Cys  Pro Asn Arg Phe Asp  Ser Trp Ala Gly Met  Ala Leu Ala 
    1085                 1090                 1095             


Arg Ala  Ser Arg Ile Gln Asp  Lys Leu Asn Ser Asn  Glu Leu Lys 
    1100                 1105                 1110             


Ser Asp  Gly Pro Ile Trp Lys  His Ala Thr Pro Val  Leu Asn Cys 
    1115                 1120                 1125             


Phe Arg  Arg Ala Leu Glu Ile  Asp Ser Ser Asn Leu  Ser Leu Trp 
    1130                 1135                 1140             


Ile Glu  Tyr Gly Thr Met Ser  Tyr Ala Leu His Ser  Phe Ala Ser 
    1145                 1150                 1155             


Arg Gln  Leu Lys Gln Trp Arg  Gly Glu Leu Pro Pro  Glu Leu Val 
    1160                 1165                 1170             


Gln Gln  Met Glu Gly Arg Arg  Asp Ser Met Leu Glu  Thr Ala Lys 
    1175                 1180                 1185             


His Cys  Phe Thr Ser Ala Ala  Arg Cys Glu Gly Asp  Gly Asp Glu 
    1190                 1195                 1200             


Glu Glu  Trp Leu Ile His Tyr  Met Leu Gly Lys Val  Ala Glu Lys 
    1205                 1210                 1215             


Gln Gln  Gln Pro Pro Thr Val  Tyr Leu Leu His Tyr  Arg Gln Ala 
    1220                 1225                 1230             


Gly His  Tyr Leu His Glu Glu  Ala Ala Arg Tyr Pro  Lys Lys Ile 
    1235                 1240                 1245             


His Tyr  His Asn Pro Pro Glu  Leu Ala Met Glu Ala  Leu Glu Val 
    1250                 1255                 1260             


Tyr Phe  Arg Leu His Ala Ser  Ile Leu Lys Leu Leu  Gly Lys Pro 
    1265                 1270                 1275             


Asp Ser  Gly Val Gly Ala Glu  Val Leu Val Asn Phe  Met Lys Glu 
    1280                 1285                 1290             


Ala Ala  Glu Gly Pro Phe Ala  Arg Gly Glu Glu Lys  Asn Thr Pro 
    1295                 1300                 1305             


Lys Ala  Ser Glu Lys Glu Lys  Ala Cys Leu Val Asp  Glu Asp Ser 
    1310                 1315                 1320             


His Ser  Ser Ala Gly Thr Leu  Pro Gly Pro Gly Ala  Ser Leu Pro 
    1325                 1330                 1335             


Ser Ser  Ser Gly Pro Gly Leu  Thr Ser Pro Pro Tyr  Thr Ala Thr 
    1340                 1345                 1350             


Pro Ile  Asp His Asp Tyr Val  Lys Cys Lys Lys Pro  His Gln Gln 
    1355                 1360                 1365             


Ala Thr  Pro Asp Asp Arg Ser  Gln Asp Ser Thr Ala  Val Ala Leu 
    1370                 1375                 1380             


Ser Asp  Ser Ser Ser Thr Gln  Asp Phe Phe Asn Glu  Pro Thr Ser 
    1385                 1390                 1395             


Leu Leu  Glu Gly Ser Arg Lys  Ser Tyr Thr Glu Lys  Arg Leu Pro 
    1400                 1405                 1410             


Ile Leu  Ser Ser Gln Ala Gly  Ala Thr Gly Lys Asp  Leu Gln Gly 
    1415                 1420                 1425             


Ala Thr  Glu Glu Arg Gly Lys  Asn Glu Glu Ser Leu  Glu Ser Thr 
    1430                 1435                 1440             


Glu Gly  Phe Arg Ala Ala Glu  Gln Gly Val Gln Lys  Pro Ala Ala 
    1445                 1450                 1455             


Glu Thr  Pro Ala Ser Ala Cys  Ile Pro Gly Lys Pro  Ser Ala Ser 
    1460                 1465                 1470             


Thr Pro  Thr Leu Trp Asp Gly  Lys Lys Arg Gly Asp  Leu Pro Gly 
    1475                 1480                 1485             


Glu Pro  Val Ala Phe Pro Gln  Gly Leu Pro Ala Gly  Ala Glu Glu 
    1490                 1495                 1500             


Gln Arg  Gln Phe Leu Thr Glu  Gln Cys Ile Ala Ser  Phe Arg Leu 
    1505                 1510                 1515             


Cys Leu  Ser Arg Phe Pro Gln  His Tyr Lys Ser Leu  Tyr Arg Leu 
    1520                 1525                 1530             


Ala Phe  Leu Tyr Thr Tyr Ser  Lys Thr His Arg Asn  Leu Gln Trp 
    1535                 1540                 1545             


Ala Arg  Asp Val Leu Leu Gly  Ser Ser Ile Pro Trp  Gln Gln Leu 
    1550                 1555                 1560             


Gln His  Met Pro Ala Gln Gly  Leu Phe Cys Glu Arg  Asn Lys Thr 
    1565                 1570                 1575             


Asn Phe  Phe Asn Gly Ile Trp  Arg Ile Pro Val Asp  Glu Ile Asp 
    1580                 1585                 1590             


Arg Pro  Gly Ser Phe Ala Trp  His Met Asn Arg Ser  Ile Val Leu 
    1595                 1600                 1605             


Leu Leu  Lys Val Leu Ala Gln  Leu Arg Asp His Ser  Thr Leu Leu 
    1610                 1615                 1620             


Lys Val  Ser Ser Met Leu Gln  Arg Thr Pro Asp Gln  Gly Lys Lys 
    1625                 1630                 1635             


Tyr Leu  Arg Asp Ala Asp Arg  Gln Val Leu Ala Gln  Arg Ala Phe 
    1640                 1645                 1650             


Ile Leu  Thr Val Lys Val Leu  Glu Asp Thr Leu Ser  Glu Leu Ala 
    1655                 1660                 1665             


Glu Gly  Ser Glu Arg Pro Gly  Pro Lys Val Cys Gly  Leu Pro Gly 
    1670                 1675                 1680             


Ala Arg  Met Thr Thr Asp Val  Ser His Lys Ala Ser  Pro Glu Asp 
    1685                 1690                 1695             


Gly Gln  Glu Gly Leu Pro Gln  Pro Lys Lys Pro Pro  Leu Ala Asp 
    1700                 1705                 1710             


Gly Ser  Gly Pro Gly Pro Glu  Pro Gly Gly Lys Val  Gly Leu Leu 
    1715                 1720                 1725             


Asn His  Arg Pro Val Ala Met  Asp Ala Gly Asp Ser  Ala Asp Gln 
    1730                 1735                 1740             


Ser Gly  Glu Arg Lys Asp Lys  Glu Ser Pro Arg Ala  Gly Pro Thr 
    1745                 1750                 1755             


Glu Pro  Met Asp Thr Ser Glu  Ala Thr Val Cys His  Ser Asp Leu 
    1760                 1765                 1770             


Glu Arg  Thr Pro Pro Leu Leu  Pro Gly Arg Pro Ala  Arg Asp Arg 
    1775                 1780                 1785             


Gly Pro  Glu Ser Arg Pro Thr  Glu Leu Ser Leu Glu  Glu Leu Ser 
    1790                 1795                 1800             


Ile Ser  Ala Arg Gln Gln Pro  Thr Pro Leu Thr Pro  Ala Gln Pro 
    1805                 1810                 1815             


Ala Pro  Ala Pro Ala Pro Ala  Thr Thr Thr Gly Thr  Arg Ala Gly 
    1820                 1825                 1830             


Gly His  Pro Glu Glu Pro Leu  Ser Arg Leu Ser Arg  Lys Arg Lys 
    1835                 1840                 1845             


Leu Leu  Glu Asp Thr Glu Ser  Gly Lys Thr Leu Leu  Leu Asp Ala 
    1850                 1855                 1860             


Tyr Arg  Val Trp Gln Gln Gly  Gln Lys Gly Val Ala  Tyr Asp Leu 
    1865                 1870                 1875             


Gly Arg  Val Glu Arg Ile Met  Ser Glu Thr Tyr Met  Leu Ile Lys 
    1880                 1885                 1890             


Gln Val  Asp Glu Glu Ala Ala  Leu Glu Gln Ala Val  Lys Phe Cys 
    1895                 1900                 1905             


Gln Val  His Leu Gly Ala Ala  Ala Gln Arg Gln Ala  Ser Gly Asp 
    1910                 1915                 1920             


Thr Pro  Thr Thr Pro Lys His  Pro Lys Asp Ser Arg  Glu Asn Phe 
    1925                 1930                 1935             


Phe Pro  Val Thr Val Val Pro  Thr Ala Pro Asp Pro  Val Pro Ala 
    1940                 1945                 1950             


Asp Ser  Val Gln Arg Pro Ser  Asp Ala His Thr Lys  Pro Arg Pro 
    1955                 1960                 1965             


Ala Leu  Ala Ala Ala Thr Thr  Ile Ile Thr Cys Pro  Pro Ser Ala 
    1970                 1975                 1980             


Ser Ala  Ser Thr Leu Asp Gln  Ser Lys Asp Pro Gly  Pro Pro Arg 
    1985                 1990                 1995             


Pro His  Arg Pro Glu Ala Thr  Pro Ser Met Ala Ser  Leu Gly Pro 
    2000                 2005                 2010             


Glu Gly  Glu Glu Leu Ala Arg  Val Ala Glu Gly Thr  Ser Phe Pro 
    2015                 2020                 2025             


Pro Gln  Glu Pro Arg His Ser  Pro Gln Val Lys Met  Ala Pro Thr 
    2030                 2035                 2040             


Ser Ser  Pro Ala Glu Pro His  Cys Trp Pro Ala Glu  Ala Ala Leu 
    2045                 2050                 2055             


Gly Thr  Gly Ala Glu Pro Thr  Cys Ser Gln Glu Gly  Lys Leu Arg 
    2060                 2065                 2070             


Pro Glu  Pro Arg Arg Asp Gly  Glu Ala Gln Glu Ala  Ala Ser Glu 
    2075                 2080                 2085             


Thr Gln  Pro Leu Ser Ser Pro  Pro Thr Ala Ala Ser  Ser Lys Ala 
    2090                 2095                 2100             


Pro Ser  Ser Gly Ser Ala Gln  Pro Pro Glu Gly His  Pro Gly Lys 
    2105                 2110                 2115             


Pro Glu  Pro Ser Arg Ala Lys  Ser Arg Pro Leu Pro  Asn Met Pro 
    2120                 2125                 2130             


Lys Leu  Val Ile Pro Ser Ala  Ala Thr Lys Phe Pro  Pro Glu Ile 
    2135                 2140                 2145             


Thr Val  Thr Pro Pro Thr Pro  Thr Leu Leu Ser Pro  Lys Gly Ser 
    2150                 2155                 2160             


Ile Ser  Glu Glu Thr Lys Gln  Lys Leu Lys Ser Ala  Ile Leu Ser 
    2165                 2170                 2175             


Ala Gln  Ser Ala Ala Asn Val  Arg Lys Glu Ser Leu  Cys Gln Pro 
    2180                 2185                 2190             


Ala Leu  Glu Val Leu Glu Thr  Ser Ser Gln Glu Ser  Ser Leu Glu 
    2195                 2200                 2205             


Ser Glu  Thr Asp Glu Asp Asp  Asp Tyr Met Asp Ile  
    2210                 2215                 2220 


<210>  1296
<211>  1602
<212>  PRT
<213>  Human

<400>  1296

Met Val Asp Ala Ser Gly Arg Ala Ala Ala Glu Gly Trp Arg Lys Met 
1               5                   10                  15      


Glu Ala Pro Pro Asp Gly Ala Ala Asp Leu Val Pro Leu Asp Arg Tyr 
            20                  25                  30          


Asp Ala Ala Arg Ala Lys Ile Ala Ala Asn Leu Gln Trp Ile Cys Ala 
        35                  40                  45              


Lys Ala Tyr Gly Arg Asp Asn Ile Pro Glu Asp Leu Arg Asp Pro Phe 
    50                  55                  60                  


Tyr Val Asp Gln Tyr Glu Gln Glu His Ile Lys Pro Pro Val Ile Lys 
65                  70                  75                  80  


Leu Leu Leu Ser Ser Glu Leu Tyr Cys Arg Val Cys Ser Leu Ile Leu 
                85                  90                  95      


Lys Gly Asp Gln Val Ala Ala Leu Gln Gly His Gln Ser Val Ile Gln 
            100                 105                 110         


Ala Leu Ser Arg Lys Gly Ile Tyr Val Met Glu Ser Asp Asp Thr Pro 
        115                 120                 125             


Val Thr Glu Ser Asp Leu Ser Arg Ala Pro Ile Lys Met Ser Ala His 
    130                 135                 140                 


Met Ala Met Val Asp Ala Leu Met Met Ala Tyr Thr Val Glu Met Ile 
145                 150                 155                 160 


Ser Ile Glu Lys Val Val Ala Ser Val Lys Arg Phe Ser Thr Phe Ser 
                165                 170                 175     


Ala Ser Lys Glu Leu Pro Tyr Asp Leu Glu Asp Ala Met Val Phe Trp 
            180                 185                 190         


Ile Asn Lys Val Asn Leu Lys Met Arg Glu Ile Thr Glu Lys Glu Val 
        195                 200                 205             


Lys Leu Lys Gln Gln Leu Leu Glu Ser Pro Ala His Gln Lys Val Arg 
    210                 215                 220                 


Tyr Arg Arg Glu His Leu Ser Ala Arg Gln Ser Pro Tyr Phe Pro Leu 
225                 230                 235                 240 


Leu Glu Asp Leu Met Arg Asp Gly Ser Asp Gly Ala Ala Leu Leu Ala 
                245                 250                 255     


Val Ile His Tyr Tyr Cys Pro Glu Gln Met Lys Leu Asp Asp Ile Cys 
            260                 265                 270         


Leu Lys Glu Val Thr Ser Met Ala Asp Ser Leu Tyr Asn Ile Arg Leu 
        275                 280                 285             


Leu Arg Glu Phe Ser Asn Glu Tyr Leu Asn Lys Cys Phe Tyr Leu Thr 
    290                 295                 300                 


Leu Glu Asp Met Leu Tyr Ala Pro Leu Val Leu Lys Pro Asn Val Met 
305                 310                 315                 320 


Val Phe Ile Ala Glu Leu Phe Trp Trp Phe Glu Asn Val Lys Pro Asp 
                325                 330                 335     


Phe Val Gln Pro Arg Asp Val Gln Glu Leu Lys Asp Ala Lys Thr Val 
            340                 345                 350         


Leu His Gln Lys Ser Ser Arg Pro Pro Val Pro Ile Ser Asn Ala Thr 
        355                 360                 365             


Lys Arg Ser Phe Leu Gly Ser Pro Ala Ala Gly Thr Leu Ala Glu Leu 
    370                 375                 380                 


Gln Pro Pro Val Gln Leu Pro Ala Glu Gly Cys His Arg His Tyr Leu 
385                 390                 395                 400 


His Pro Glu Glu Pro Glu Tyr Leu Gly Lys Gly Thr Ala Ala Phe Ser 
                405                 410                 415     


Pro Ser His Pro Leu Leu Pro Leu Arg Gln Lys Gln Gln Lys Ser Ile 
            420                 425                 430         


Gln Gly Glu Asp Ile Pro Asp Gln Arg His Arg Ser Asn Ser Leu Thr 
        435                 440                 445             


Arg Val Asp Gly Gln Pro Arg Gly Ala Ala Ile Ala Trp Pro Glu Lys 
    450                 455                 460                 


Lys Thr Arg Pro Ala Ser Gln Pro Thr Pro Phe Ala Leu His His Ala 
465                 470                 475                 480 


Ala Ser Cys Glu Val Asp Pro Ser Ser Gly Asp Ser Ile Ser Leu Ala 
                485                 490                 495     


Arg Ser Ile Ser Lys Asp Ser Leu Ala Ser Asn Ile Val Asn Leu Thr 
            500                 505                 510         


Pro Gln Asn Gln Pro His Pro Thr Ala Thr Lys Ser His Gly Lys Ser 
        515                 520                 525             


Leu Leu Ser Asn Val Ser Ile Glu Asp Glu Glu Glu Glu Leu Val Ala 
    530                 535                 540                 


Ile Val Arg Ala Asp Val Val Pro Gln Gln Ala Asp Pro Glu Phe Pro 
545                 550                 555                 560 


Arg Ala Ser Pro Arg Ala Leu Gly Leu Thr Ala Asn Ala Arg Ser Pro 
                565                 570                 575     


Gln Gly Gln Leu Asp Thr Ser Glu Ser Lys Pro Asp Ser Phe Phe Leu 
            580                 585                 590         


Glu Pro Leu Met Pro Ala Val Leu Lys Pro Ala Lys Glu Lys Gln Val 
        595                 600                 605             


Ile Thr Lys Glu Asp Glu Arg Gly Glu Gly Arg Pro Arg Ser Ile Val 
    610                 615                 620                 


Ser Arg Arg Pro Ser Glu Gly Pro Gln Pro Leu Val Arg Arg Lys Met 
625                 630                 635                 640 


Thr Gly Ser Arg Asp Leu Asn Arg Thr Phe Thr Pro Ile Pro Cys Ser 
                645                 650                 655     


Glu Phe Pro Met Gly Ile Asp Pro Thr Glu Thr Gly Pro Leu Ser Val 
            660                 665                 670         


Glu Thr Ala Gly Glu Val Cys Gly Gly Pro Leu Ala Leu Gly Gly Phe 
        675                 680                 685             


Asp Pro Phe Pro Gln Gly Pro Ser Thr Asp Gly Phe Phe Leu His Val 
    690                 695                 700                 


Gly Arg Ala Asp Glu Asp Thr Glu Gly Arg Leu Tyr Val Ser Cys Ser 
705                 710                 715                 720 


Lys Ser Pro Asn Ser His Asp Ser Glu Pro Trp Thr Leu Leu Arg Gln 
                725                 730                 735     


Asp Ser Asp Ser Asp Val Val Asp Ile Glu Glu Ala Glu His Asp Phe 
            740                 745                 750         


Met Gly Glu Ala His Pro Val Val Phe Ser Arg Tyr Ile Gly Glu Glu 
        755                 760                 765             


Glu Ser Ala Lys Leu Gln Glu Asp Met Lys Val Lys Glu His Glu Asp 
    770                 775                 780                 


Lys Asp Asp Ala Ser Gly Arg Ser Ser Pro Cys Leu Ser Thr Ala Ser 
785                 790                 795                 800 


Gln Met Ser Ser Val Ser Met Ala Ser Gly Ser Val Lys Met Thr Ser 
                805                 810                 815     


Phe Ala Glu Arg Lys Leu Gln Arg Leu Asn Ser Cys Glu Thr Lys Ser 
            820                 825                 830         


Ser Thr Ser Ser Ser Gln Lys Thr Thr Pro Asp Ala Ser Glu Ser Cys 
        835                 840                 845             


Pro Ala Pro Leu Thr Thr Trp Arg Gln Lys Arg Glu Gln Ser Pro Ser 
    850                 855                 860                 


Gln His Gly Lys Asp Pro Ala Ser Leu Leu Ala Ser Glu Leu Val Gln 
865                 870                 875                 880 


Leu His Met Gln Leu Glu Glu Lys Arg Arg Ala Ile Glu Ala Gln Lys 
                885                 890                 895     


Lys Lys Met Glu Ala Leu Ser Ala Arg Gln Arg Leu Lys Leu Gly Lys 
            900                 905                 910         


Ala Ala Phe Leu His Val Val Lys Lys Gly Lys Ala Glu Ala Ala Pro 
        915                 920                 925             


Pro Leu Arg Pro Glu His Phe Ala Lys Glu Tyr Ser Gln His Asn Gly 
    930                 935                 940                 


Glu Asp Cys Gly Asp Ala Val Ser Lys Thr Glu Asp Phe Leu Val Lys 
945                 950                 955                 960 


Glu Glu Gln Arg Glu Glu Leu Leu His Glu Pro Gln Asp Val Asp Lys 
                965                 970                 975     


Glu Ser Leu Ala Phe Ala Gln Gln His Lys Ala Lys Asp Pro Val Ala 
            980                 985                 990         


Leu His Glu Leu Glu Arg Asn Lys  Val Ile Ser Ala Ala  Leu Leu Glu 
        995                 1000                 1005             


Asp Thr  Val Gly Glu Val Val  Asp Val Asn Glu Cys  Asp Leu Ser 
    1010                 1015                 1020             


Ile Glu  Lys Leu Asn Glu Thr  Ile Ser Thr Leu Gln  Gln Ala Ile 
    1025                 1030                 1035             


Leu Lys  Ile Ser Gln Gln Gln  Glu Gln Leu Leu Met  Lys Ser Pro 
    1040                 1045                 1050             


Thr Val  Pro Val Pro Gly Ser  Lys Asn Asn Ser Gln  Asp His Lys 
    1055                 1060                 1065             


Val Lys  Ala Pro Val His Phe  Val Glu Pro Leu Ser  Pro Thr Gly 
    1070                 1075                 1080             


Val Ala  Gly His Arg Lys Ala  Pro Arg Leu Gly Gln  Gly Arg Asn 
    1085                 1090                 1095             


Ser Arg  Ser Gly Arg Pro Ala  Glu Leu Lys Val Pro  Lys Asp Arg 
    1100                 1105                 1110             


Pro Gln  Gly Ser Ser Arg Ser  Lys Thr Pro Thr Pro  Ser Val Glu 
    1115                 1120                 1125             


Thr Leu  Pro His Leu Arg Pro  Phe Pro Ala Ser Ser  His Pro Arg 
    1130                 1135                 1140             


Thr Pro  Thr Asp Pro Gly Leu  Asp Ser Ala Leu Glu  Pro Ser Gly 
    1145                 1150                 1155             


Asp Pro  His Gly Lys Cys Leu  Phe Asp Ser Tyr Arg  Leu His Asp 
    1160                 1165                 1170             


Glu Ser  Asn Gln Arg Thr Leu  Thr Leu Ser Ser Ser  Lys Asp Ala 
    1175                 1180                 1185             


Asn Ile  Leu Ser Glu Gln Met  Ser Leu Lys Glu Val  Leu Asp Ala 
    1190                 1195                 1200             


Ser Val  Lys Glu Val Gly Ser  Ser Ser Ser Asp Val  Ser Gly Lys 
    1205                 1210                 1215             


Glu Ser  Val Pro Val Glu Glu  Pro Leu Arg Ser Arg  Ala Ser Leu 
    1220                 1225                 1230             


Ile Glu  Val Asp Leu Ser Asp  Leu Lys Ala Pro Asp  Glu Asp Gly 
    1235                 1240                 1245             


Glu Leu  Val Ser Leu Asp Gly  Ser Ala Asp Leu Val  Ser Glu Gly 
    1250                 1255                 1260             


Asp Gln  Lys Pro Gly Val Gly  Phe Phe Phe Lys Asp  Glu Gln Lys 
    1265                 1270                 1275             


Ala Glu  Asp Glu Leu Ala Lys  Lys Arg Ala Ala Phe  Leu Leu Lys 
    1280                 1285                 1290             


Gln Gln  Arg Lys Ala Glu Glu  Ala Arg Val Arg Lys  Gln Gln Leu 
    1295                 1300                 1305             


Glu Ala  Glu Val Glu Leu Lys  Arg Asp Glu Ala Arg  Arg Lys Ala 
    1310                 1315                 1320             


Glu Glu  Asp Arg Val Arg Lys  Glu Glu Glu Lys Ala  Arg Arg Glu 
    1325                 1330                 1335             


Leu Ile  Lys Gln Glu Tyr Leu  Arg Arg Lys Gln Gln  Gln Ile Leu 
    1340                 1345                 1350             


Glu Glu  Gln Gly Leu Gly Lys  Pro Lys Ser Lys Pro  Lys Lys Pro 
    1355                 1360                 1365             


Arg Pro  Lys Ser Val His Arg  Glu Glu Ser Cys Ser  Asp Ser Gly 
    1370                 1375                 1380             


Thr Lys  Cys Ser Ser Thr Pro  Asp Asn Leu Ser Arg  Thr Gln Ser 
    1385                 1390                 1395             


Gly Ser  Ser Leu Ser Leu Ala  Ser Ala Ala Thr Thr  Glu Pro Glu 
    1400                 1405                 1410             


Ser Val  His Ser Gly Gly Thr  Pro Ser Gln Arg Val  Glu Ser Met 
    1415                 1420                 1425             


Glu Ala  Leu Pro Ile Leu Ser  Arg Asn Pro Ser Arg  Ser Thr Asp 
    1430                 1435                 1440             


Arg Asp  Trp Glu Thr Ala Ser  Ala Ala Ser Ser Leu  Ala Ser Val 
    1445                 1450                 1455             


Ala Glu  Tyr Thr Gly Pro Lys  Leu Phe Lys Glu Pro  Ser Ser Lys 
    1460                 1465                 1470             


Ser Asn  Lys Pro Ile Ile His  Asn Ala Ile Ser His  Cys Cys Leu 
    1475                 1480                 1485             


Ala Gly  Lys Val Asn Glu Pro  His Lys Asn Ser Ile  Leu Glu Glu 
    1490                 1495                 1500             


Leu Glu  Lys Cys Asp Ala Asn  His Tyr Ile Ile Leu  Phe Arg Asp 
    1505                 1510                 1515             


Ala Gly  Cys Gln Phe Arg Ala  Leu Tyr Cys Tyr Tyr  Pro Asp Thr 
    1520                 1525                 1530             


Glu Glu  Ile Tyr Lys Leu Thr  Gly Thr Gly Pro Lys  Asn Ile Thr 
    1535                 1540                 1545             


Lys Lys  Met Ile Asp Lys Leu  Tyr Lys Tyr Ser Ser  Asp Arg Lys 
    1550                 1555                 1560             


Gln Phe  Asn Leu Ile Pro Ala  Lys Thr Met Ser Val  Ser Val Asp 
    1565                 1570                 1575             


Ala Leu  Thr Ile His Asn His  Leu Trp Gln Pro Lys  Arg Pro Ala 
    1580                 1585                 1590             


Val Pro  Lys Lys Ala Gln Thr  Arg Lys 
    1595                 1600         


<210>  1297
<211>  474
<212>  PRT
<213>  Human

<400>  1297

Met Ala Leu Ala Val Ala Pro Trp Gly Arg Gln Trp Glu Glu Ala Arg 
1               5                   10                  15      


Ala Leu Gly Arg Ala Val Arg Met Leu Gln Arg Leu Glu Glu Gln Cys 
            20                  25                  30          


Val Asp Pro Arg Leu Ser Val Ser Pro Pro Ser Leu Arg Asp Leu Leu 
        35                  40                  45              


Pro Arg Thr Ala Gln Leu Leu Arg Glu Val Ala His Ser Arg Arg Ala 
    50                  55                  60                  


Ala Gly Gly Gly Gly Pro Gly Gly Pro Gly Gly Ser Gly Asp Phe Leu 
65                  70                  75                  80  


Leu Ile Tyr Leu Ala Asn Leu Glu Ala Lys Ser Arg Gln Val Ala Ala 
                85                  90                  95      


Leu Leu Pro Pro Arg Gly Arg Arg Ser Ala Asn Asp Glu Leu Phe Arg 
            100                 105                 110         


Ala Gly Ser Arg Leu Arg Arg Gln Leu Ala Lys Leu Ala Ile Ile Phe 
        115                 120                 125             


Ser His Met His Ala Glu Leu His Ala Leu Phe Pro Gly Gly Lys Tyr 
    130                 135                 140                 


Cys Gly His Met Tyr Gln Leu Thr Lys Ala Pro Ala His Thr Phe Trp 
145                 150                 155                 160 


Arg Glu Ser Cys Gly Ala Arg Cys Val Leu Pro Trp Ala Glu Phe Glu 
                165                 170                 175     


Ser Leu Leu Gly Thr Cys His Pro Val Glu Pro Gly Cys Thr Ala Leu 
            180                 185                 190         


Ala Leu Arg Thr Thr Ile Asp Leu Thr Cys Ser Gly His Val Ser Ile 
        195                 200                 205             


Phe Glu Phe Asp Val Phe Thr Arg Leu Phe Gln Pro Trp Pro Thr Leu 
    210                 215                 220                 


Leu Lys Asn Trp Gln Leu Leu Ala Val Asn His Pro Gly Tyr Met Ala 
225                 230                 235                 240 


Phe Leu Thr Tyr Asp Glu Val Gln Glu Arg Leu Gln Ala Cys Arg Asp 
                245                 250                 255     


Lys Pro Gly Ser Tyr Ile Phe Arg Pro Ser Cys Thr Arg Leu Gly Gln 
            260                 265                 270         


Trp Ala Ile Gly Tyr Val Ser Ser Asp Gly Ser Ile Leu Gln Thr Ile 
        275                 280                 285             


Pro Ala Asn Lys Pro Leu Ser Gln Val Leu Leu Glu Gly Gln Lys Asp 
    290                 295                 300                 


Gly Phe Tyr Leu Tyr Pro Asp Gly Lys Thr His Asn Pro Asp Leu Thr 
305                 310                 315                 320 


Glu Leu Gly Gln Ala Glu Pro Gln Gln Arg Ile His Val Ser Glu Glu 
                325                 330                 335     


Gln Leu Gln Leu Tyr Trp Ala Met Asp Ser Thr Phe Glu Leu Cys Lys 
            340                 345                 350         


Ile Cys Ala Glu Ser Asn Lys Asp Val Lys Ile Glu Pro Cys Gly His 
        355                 360                 365             


Leu Leu Cys Ser Cys Cys Leu Ala Ala Trp Gln His Ser Asp Ser Gln 
    370                 375                 380                 


Thr Cys Pro Phe Cys Arg Cys Glu Ile Lys Gly Trp Glu Ala Val Ser 
385                 390                 395                 400 


Ile Tyr Gln Phe His Gly Gln Ala Thr Ala Glu Asp Ser Gly Asn Ser 
                405                 410                 415     


Ser Asp Gln Glu Gly Arg Glu Leu Glu Leu Gly Gln Val Pro Leu Ser 
            420                 425                 430         


Ala Pro Pro Leu Pro Pro Arg Pro Asp Leu Pro Pro Arg Lys Pro Arg 
        435                 440                 445             


Asn Ala Gln Pro Lys Val Arg Leu Leu Lys Gly Asn Ser Pro Pro Ala 
    450                 455                 460                 


Ala Leu Gly Pro Gln Asp Pro Ala Pro Ala 
465                 470                 


<210>  1298
<211>  224
<212>  PRT
<213>  Human

<400>  1298

Met Ala Ala Pro Ser Glu Val Ala Ala Ile Ala Pro Gly Glu Gly Asp 
1               5                   10                  15      


Gly Gly Gly Gly Gly Phe Gly Ser Trp Leu Asp Gly Arg Leu Glu Ala 
            20                  25                  30          


Leu Gly Val Asp Arg Ala Val Tyr Gly Ala Tyr Ile Leu Gly Ile Leu 
        35                  40                  45              


Gln Glu Glu Glu Glu Glu Glu Lys Leu Asp Ala Leu Gln Gly Ile Leu 
    50                  55                  60                  


Ser Ala Phe Leu Glu Glu Asp Ser Leu Leu Asn Ile Cys Lys Glu Ile 
65                  70                  75                  80  


Val Glu Arg Trp Ser Glu Thr Gln Asn Val Val Thr Lys Val Lys Lys 
                85                  90                  95      


Glu Asp Glu Val Gln Ala Ile Ala Thr Leu Ile Glu Lys Gln Ala Gln 
            100                 105                 110         


Ile Val Val Lys Pro Arg Met Val Ser Glu Glu Glu Lys Gln Arg Lys 
        115                 120                 125             


Ala Ala Leu Leu Ala Gln Tyr Ala Asp Val Thr Asp Glu Glu Asp Glu 
    130                 135                 140                 


Ala Asp Glu Lys Asp Asp Ser Gly Ala Thr Thr Met Asn Ile Gly Ser 
145                 150                 155                 160 


Asp Lys Leu Leu Phe Arg Asn Thr Asn Val Glu Asp Val Leu Asn Ala 
                165                 170                 175     


Arg Lys Leu Glu Arg Asp Ser Leu Arg Asp Glu Ser Gln Arg Lys Lys 
            180                 185                 190         


Glu Gln Asp Lys Leu Gln Arg Glu Arg Asp Lys Leu Ala Lys Gln Glu 
        195                 200                 205             


Arg Lys Glu Lys Glu Lys Lys Arg Thr Gln Arg Gly Glu Arg Lys Arg 
    210                 215                 220                 


<210>  1299
<211>  70
<212>  PRT
<213>  Human

<400>  1299

Met Tyr Phe Arg Phe Ile Pro Val Lys Gln Gln Leu Glu Leu Gln Val 
1               5                   10                  15      


Thr Pro Pro Arg Val Leu Pro Thr Leu Gly Trp Pro Gln Ile Gln Leu 
            20                  25                  30          


Met Pro Pro Pro Arg Arg Leu Val Val Pro Cys Ser Gln Gln Pro Val 
        35                  40                  45              


Ser Ser Trp Ser His Ser Leu Phe Cys Ile Ser Thr Leu Lys Arg Leu 
    50                  55                  60                  


Arg Pro Arg Asn Val Phe 
65                  70  


<210>  1300
<211>  378
<212>  PRT
<213>  Human

<400>  1300

Met Val Asp Tyr Ser Val Trp Asp His Ile Glu Val Ser Asp Asp Glu 
1               5                   10                  15      


Asp Glu Thr His Pro Asn Ile Asp Thr Ala Ser Leu Phe Arg Trp Arg 
            20                  25                  30          


His Gln Ala Arg Val Glu Arg Met Glu Gln Phe Gln Lys Glu Lys Glu 
        35                  40                  45              


Glu Leu Asp Arg Gly Cys Arg Glu Cys Lys Arg Lys Val Ala Glu Cys 
    50                  55                  60                  


Gln Arg Lys Leu Lys Glu Leu Glu Val Ala Glu Gly Gly Lys Ala Glu 
65                  70                  75                  80  


Leu Glu Arg Leu Gln Ala Glu Ala Gln Gln Leu Arg Lys Glu Glu Arg 
                85                  90                  95      


Ser Trp Glu Gln Lys Leu Glu Glu Met Arg Lys Lys Glu Lys Ser Met 
            100                 105                 110         


Pro Trp Asn Val Asp Thr Leu Ser Lys Asp Gly Phe Ser Lys Ser Met 
        115                 120                 125             


Val Asn Thr Lys Pro Glu Lys Thr Glu Glu Asp Ser Glu Glu Val Arg 
    130                 135                 140                 


Glu Gln Lys His Lys Thr Phe Val Glu Lys Tyr Glu Lys Gln Ile Lys 
145                 150                 155                 160 


His Phe Gly Met Leu Arg Arg Trp Asp Asp Ser Gln Lys Tyr Leu Ser 
                165                 170                 175     


Asp Asn Val His Leu Val Cys Glu Glu Thr Ala Asn Tyr Leu Val Ile 
            180                 185                 190         


Trp Cys Ile Asp Leu Glu Val Glu Glu Lys Cys Ala Leu Met Glu Gln 
        195                 200                 205             


Val Ala His Gln Thr Ile Val Met Gln Phe Ile Leu Glu Leu Ala Lys 
    210                 215                 220                 


Ser Leu Lys Val Asp Pro Arg Ala Cys Phe Arg Gln Phe Phe Thr Lys 
225                 230                 235                 240 


Ile Lys Thr Ala Asp Arg Gln Tyr Met Glu Gly Phe Asn Asp Glu Leu 
                245                 250                 255     


Glu Ala Phe Lys Glu Arg Val Arg Gly Arg Ala Lys Leu Arg Ile Glu 
            260                 265                 270         


Lys Ala Met Lys Glu Tyr Glu Glu Glu Glu Arg Lys Lys Arg Leu Gly 
        275                 280                 285             


Pro Gly Gly Leu Asp Pro Val Glu Val Tyr Glu Ser Leu Pro Glu Glu 
    290                 295                 300                 


Leu Gln Lys Cys Phe Asp Val Lys Asp Val Gln Met Leu Gln Asp Ala 
305                 310                 315                 320 


Ile Ser Lys Met Asp Pro Thr Asp Ala Lys Tyr His Met Gln Arg Cys 
                325                 330                 335     


Ile Asp Ser Gly Leu Trp Val Pro Asn Ser Lys Ala Ser Glu Ala Lys 
            340                 345                 350         


Glu Gly Glu Glu Ala Gly Pro Gly Asp Pro Leu Leu Glu Ala Val Pro 
        355                 360                 365             


Lys Thr Gly Asp Glu Lys Asp Val Ser Val 
    370                 375             


<210>  1301
<211>  1054
<212>  PRT
<213>  Human

<400>  1301

Met Ala Ala Val Lys Glu Pro Leu Glu Phe His Ala Lys Arg Pro Trp 
1               5                   10                  15      


Arg Pro Glu Glu Ala Val Glu Asp Pro Asp Glu Glu Asp Glu Asp Asn 
            20                  25                  30          


Thr Ser Glu Ala Glu Asn Gly Phe Ser Leu Glu Glu Val Leu Arg Leu 
        35                  40                  45              


Gly Gly Thr Lys Gln Asp Tyr Leu Met Leu Ala Thr Leu Asp Glu Asn 
    50                  55                  60                  


Glu Glu Val Ile Asp Gly Gly Lys Lys Gly Ala Ile Asp Asp Leu Gln 
65                  70                  75                  80  


Gln Gly Glu Leu Glu Ala Phe Ile Gln Asn Leu Asn Leu Ala Lys Tyr 
                85                  90                  95      


Thr Lys Ala Ser Leu Val Glu Glu Asp Glu Pro Ala Glu Lys Glu Asn 
            100                 105                 110         


Ser Ser Lys Lys Glu Val Lys Ile Pro Lys Ile Asn Asn Lys Asn Thr 
        115                 120                 125             


Ala Glu Ser Gln Arg Thr Ser Val Asn Lys Val Lys Asn Lys Asn Arg 
    130                 135                 140                 


Pro Glu Pro His Ser Asp Glu Asn Gly Ser Thr Thr Pro Lys Val Lys 
145                 150                 155                 160 


Lys Asp Lys Gln Asn Ile Phe Glu Phe Phe Glu Arg Gln Thr Leu Leu 
                165                 170                 175     


Leu Arg Pro Gly Gly Lys Trp Tyr Asp Leu Glu Tyr Ser Asn Glu Tyr 
            180                 185                 190         


Ser Leu Lys Pro Gln Pro Gln Asp Val Val Ser Lys Tyr Lys Thr Leu 
        195                 200                 205             


Ala Gln Lys Leu Tyr Gln His Glu Ile Asn Leu Phe Lys Ser Lys Thr 
    210                 215                 220                 


Asn Ser Gln Lys Gly Ala Ser Ser Thr Trp Met Lys Ala Ile Val Ser 
225                 230                 235                 240 


Ser Gly Thr Leu Gly Asp Arg Met Ala Ala Met Ile Leu Leu Ile Gln 
                245                 250                 255     


Asp Asp Ala Val His Thr Leu Gln Phe Val Glu Thr Leu Val Asn Leu 
            260                 265                 270         


Val Lys Lys Lys Gly Ser Lys Gln Gln Cys Leu Met Ala Leu Asp Thr 
        275                 280                 285             


Phe Lys Glu Leu Leu Ile Thr Asp Leu Leu Pro Asp Asn Arg Lys Leu 
    290                 295                 300                 


Arg Ile Phe Ser Gln Arg Pro Phe Asp Lys Leu Glu Gln Leu Ser Ser 
305                 310                 315                 320 


Gly Asn Lys Asp Ser Arg Asp Arg Arg Leu Ile Leu Trp Tyr Phe Glu 
                325                 330                 335     


His Gln Leu Lys His Leu Val Ala Glu Phe Val Gln Val Leu Glu Thr 
            340                 345                 350         


Leu Ser His Asp Thr Leu Val Thr Thr Lys Thr Arg Ala Leu Thr Val 
        355                 360                 365             


Ala His Glu Leu Leu Cys Asn Lys Pro Glu Glu Glu Lys Ala Leu Leu 
    370                 375                 380                 


Val Gln Val Val Asn Lys Leu Gly Asp Pro Gln Asn Arg Ile Ala Thr 
385                 390                 395                 400 


Lys Ala Ser His Leu Leu Glu Thr Leu Leu Cys Lys His Pro Asn Met 
                405                 410                 415     


Lys Gly Val Val Ser Gly Glu Val Glu Arg Leu Leu Phe Arg Ser Asn 
            420                 425                 430         


Ile Ser Ser Lys Ala Gln Tyr Tyr Ala Ile Cys Phe Leu Asn Gln Met 
        435                 440                 445             


Ala Leu Ser His Glu Glu Ser Glu Leu Ala Asn Lys Leu Ile Thr Val 
    450                 455                 460                 


Tyr Phe Cys Phe Phe Arg Thr Cys Val Lys Lys Lys Asp Val Glu Ser 
465                 470                 475                 480 


Lys Met Leu Ser Ala Leu Leu Thr Gly Val Asn Arg Ala Tyr Pro Tyr 
                485                 490                 495     


Ser Gln Thr Gly Asp Asp Lys Val Arg Glu Gln Ile Asp Thr Leu Phe 
            500                 505                 510         


Lys Val Leu His Ile Val Asn Phe Asn Thr Ser Val Gln Ala Leu Met 
        515                 520                 525             


Leu Leu Phe Gln Val Met Asn Ser Gln Gln Thr Ile Ser Asp Arg Tyr 
    530                 535                 540                 


Tyr Thr Ala Leu Tyr Arg Lys Met Leu Asp Pro Gly Leu Met Thr Cys 
545                 550                 555                 560 


Ser Lys Gln Ala Met Phe Leu Asn Leu Val Tyr Lys Ser Leu Lys Ala 
                565                 570                 575     


Asp Ile Val Leu Arg Arg Val Lys Ala Phe Val Lys Arg Leu Leu Gln 
            580                 585                 590         


Val Thr Cys Gln Gln Met Pro Pro Phe Ile Cys Gly Ala Leu Tyr Leu 
        595                 600                 605             


Val Ser Glu Ile Leu Lys Ala Lys Pro Gly Leu Arg Ser Gln Leu Asp 
    610                 615                 620                 


Asp His Pro Glu Ser Asp Asp Glu Glu Asn Phe Ile Asp Ala Asn Asp 
625                 630                 635                 640 


Asp Glu Asp Met Glu Lys Phe Thr Asp Ala Asp Lys Glu Thr Glu Ile 
                645                 650                 655     


Val Lys Lys Leu Glu Thr Glu Glu Thr Val Pro Glu Thr Asp Val Glu 
            660                 665                 670         


Thr Lys Lys Pro Glu Val Ala Ser Trp Val His Phe Asp Asn Leu Lys 
        675                 680                 685             


Gly Gly Lys Gln Leu Asn Lys Tyr Asp Pro Phe Ser Arg Asn Pro Leu 
    690                 695                 700                 


Phe Cys Gly Ala Glu Asn Thr Ser Leu Trp Glu Leu Lys Lys Leu Ser 
705                 710                 715                 720 


Val His Phe His Pro Ser Val Ala Leu Phe Ala Lys Thr Ile Leu Gln 
                725                 730                 735     


Gly Asn Tyr Ile Gln Tyr Ser Gly Asp Pro Leu Gln Asp Phe Thr Leu 
            740                 745                 750         


Met Arg Phe Leu Asp Arg Phe Val Tyr Arg Asn Pro Lys Pro His Lys 
        755                 760                 765             


Gly Lys Glu Asn Thr Asp Ser Val Val Met Gln Pro Lys Arg Lys His 
    770                 775                 780                 


Phe Ile Lys Asp Ile Arg His Leu Pro Val Asn Ser Lys Glu Phe Leu 
785                 790                 795                 800 


Ala Lys Glu Glu Ser Gln Ile Pro Val Asp Glu Val Phe Phe His Arg 
                805                 810                 815     


Tyr Tyr Lys Lys Val Ala Val Lys Glu Lys Gln Lys Arg Asp Ala Asp 
            820                 825                 830         


Glu Glu Ser Ile Glu Asp Val Asp Asp Glu Glu Phe Glu Glu Leu Ile 
        835                 840                 845             


Asp Thr Phe Glu Asp Asp Asn Cys Phe Ser Ser Gly Lys Asp Asp Met 
    850                 855                 860                 


Asp Phe Ala Gly Asn Val Lys Lys Arg Thr Lys Gly Ala Lys Asp Asn 
865                 870                 875                 880 


Thr Leu Asp Glu Asp Ser Glu Gly Ser Asp Asp Glu Leu Gly Asn Leu 
                885                 890                 895     


Asp Asp Asp Glu Val Ser Leu Gly Ser Met Asp Asp Glu Glu Phe Ala 
            900                 905                 910         


Glu Val Asp Glu Asp Gly Gly Thr Phe Met Asp Val Leu Asp Asp Glu 
        915                 920                 925             


Ser Glu Ser Val Pro Glu Leu Glu Val His Ser Lys Val Ser Thr Lys 
    930                 935                 940                 


Lys Ser Lys Arg Lys Gly Thr Asp Asp Phe Asp Phe Ala Gly Ser Phe 
945                 950                 955                 960 


Gln Gly Pro Arg Lys Lys Lys Arg Asn Leu Asn Asp Ser Ser Leu Phe 
                965                 970                 975     


Val Ser Ala Glu Glu Phe Gly His Leu Leu Asp Glu Asn Met Gly Ser 
            980                 985                 990         


Lys Phe Asp Asn Ile Gly Met Asn  Ala Met Ala Asn Lys  Asp Asn Ala 
        995                 1000                 1005             


Ser Leu  Lys Gln Leu Arg Trp  Glu Ala Glu Arg Asp  Asp Trp Leu 
    1010                 1015                 1020             


His Asn  Arg Asp Ala Lys Ser  Ile Ile Lys Lys Lys  Lys His Phe 
    1025                 1030                 1035             


Lys Lys  Lys Arg Ile Lys Thr  Thr Gln Lys Thr Lys  Lys Gln Arg 
    1040                 1045                 1050             


Lys 
    


<210>  1302
<211>  219
<212>  PRT
<213>  Human

<400>  1302

Met Asn Arg Leu Phe Gly Lys Ala Lys Pro Lys Ala Pro Pro Pro Ser 
1               5                   10                  15      


Leu Thr Asp Cys Ile Gly Thr Val Asp Ser Arg Ala Glu Ser Ile Asp 
            20                  25                  30          


Lys Lys Ile Ser Arg Leu Asp Ala Glu Leu Val Lys Tyr Lys Asp Gln 
        35                  40                  45              


Ile Lys Lys Met Arg Glu Gly Pro Ala Lys Asn Met Val Lys Gln Lys 
    50                  55                  60                  


Ala Leu Arg Val Leu Lys Gln Lys Arg Met Tyr Glu Gln Gln Arg Asp 
65                  70                  75                  80  


Asn Leu Ala Gln Gln Ser Phe Asn Met Glu Gln Ala Asn Tyr Thr Ile 
                85                  90                  95      


Gln Ser Leu Lys Asp Thr Lys Thr Thr Val Asp Ala Met Lys Leu Gly 
            100                 105                 110         


Val Lys Glu Met Lys Lys Ala Tyr Lys Gln Val Lys Ile Asp Gln Ile 
        115                 120                 125             


Glu Asp Leu Gln Asp Gln Leu Glu Asp Met Met Glu Asp Ala Asn Glu 
    130                 135                 140                 


Ile Gln Glu Ala Leu Ser Arg Ser Tyr Gly Thr Pro Glu Leu Asp Glu 
145                 150                 155                 160 


Asp Asp Leu Glu Ala Glu Leu Asp Ala Leu Gly Asp Glu Leu Leu Ala 
                165                 170                 175     


Asp Glu Asp Ser Ser Tyr Leu Asp Glu Ala Ala Ser Ala Pro Ala Ile 
            180                 185                 190         


Pro Glu Gly Val Pro Thr Asp Thr Lys Asn Lys Asp Gly Val Leu Val 
        195                 200                 205             


Asp Glu Phe Gly Leu Pro Gln Ile Pro Ala Ser 
    210                 215                 


<210>  1303
<211>  975
<212>  PRT
<213>  Human

<400>  1303

Met Glu Asp Tyr Glu Gln Glu Leu Cys Gly Val Glu Asp Asp Phe His 
1               5                   10                  15      


Asn Gln Phe Ala Ala Glu Leu Glu Val Leu Ala Glu Leu Glu Gly Ala 
            20                  25                  30          


Ser Thr Pro Ser Pro Ser Gly Val Pro Leu Phe Thr Ala Gly Arg Pro 
        35                  40                  45              


Pro Arg Thr Phe Glu Glu Ala Leu Ala Arg Gly Asp Ala Ala Ser Ser 
    50                  55                  60                  


Pro Ala Pro Ala Ala Ser Val Gly Ser Ser Gln Gly Gly Ala Arg Lys 
65                  70                  75                  80  


Arg Gln Val Asp Ala Asp Leu Gln Pro Ala Gly Ser Leu Pro His Ala 
                85                  90                  95      


Pro Arg Ile Lys Arg Pro Arg Leu Gln Val Val Lys Arg Leu Asn Phe 
            100                 105                 110         


Arg Ser Glu Glu Met Glu Glu Pro Pro Pro Pro Asp Ser Ser Pro Thr 
        115                 120                 125             


Asp Ile Thr Pro Pro Pro Ser Pro Glu Asp Leu Ala Glu Leu Trp Gly 
    130                 135                 140                 


His Gly Val Ser Glu Ala Ala Ala Asp Val Gly Leu Thr Arg Ala Ser 
145                 150                 155                 160 


Pro Ala Ala Arg Asn Pro Val Leu Arg Arg Pro Pro Ile Leu Glu Asp 
                165                 170                 175     


Tyr Val His Val Thr Ser Thr Glu Gly Val Arg Ala Tyr Leu Val Leu 
            180                 185                 190         


Arg Ala Asp Pro Met Ala Pro Gly Val Gln Gly Ser Leu Leu His Val 
        195                 200                 205             


Pro Trp Arg Gly Gly Gly Gln Leu Asp Leu Leu Gly Val Ser Leu Ala 
    210                 215                 220                 


Ser Leu Lys Lys Gln Val Asp Gly Glu Arg Arg Glu Arg Leu Leu Gln 
225                 230                 235                 240 


Glu Ala Gln Lys Leu Ser Asp Thr Leu His Ser Leu Arg Ser Gly Glu 
                245                 250                 255     


Glu Glu Ala Ala Gln Pro Leu Gly Ala Pro Glu Glu Glu Pro Thr Asp 
            260                 265                 270         


Gly Gln Asp Ala Ser Ser His Cys Leu Trp Val Asp Glu Phe Ala Pro 
        275                 280                 285             


Arg His Tyr Thr Glu Leu Leu Ser Asp Asp Phe Thr Asn Arg Cys Leu 
    290                 295                 300                 


Leu Lys Trp Leu Lys Leu Trp Asp Leu Val Val Phe Gly His Glu Arg 
305                 310                 315                 320 


Pro Ser Arg Lys Pro Arg Pro Ser Val Glu Pro Ala Arg Val Ser Lys 
                325                 330                 335     


Glu Ala Thr Ala Pro Gly Lys Trp Lys Ser His Glu Gln Val Leu Glu 
            340                 345                 350         


Glu Met Leu Glu Ala Gly Leu Asp Pro Ser Gln Arg Pro Lys Gln Lys 
        355                 360                 365             


Val Ala Leu Leu Cys Gly Pro Pro Gly Leu Gly Lys Thr Thr Leu Ala 
    370                 375                 380                 


His Val Ile Ala Arg His Ala Gly Tyr Ser Val Val Glu Met Asn Ala 
385                 390                 395                 400 


Ser Asp Asp Arg Ser Pro Glu Val Phe Arg Thr Arg Ile Glu Ala Ala 
                405                 410                 415     


Thr Gln Met Glu Ser Val Leu Gly Ala Gly Gly Lys Pro Asn Cys Leu 
            420                 425                 430         


Val Ile Asp Glu Ile Asp Gly Ala Pro Val Ala Ala Ile Asn Val Leu 
        435                 440                 445             


Leu Ser Ile Leu Asn Arg Lys Gly Pro Gln Glu Val Gly Pro Gln Gly 
    450                 455                 460                 


Pro Ala Val Pro Ser Gly Gly Gly Arg Arg Arg Arg Ala Glu Gly Gly 
465                 470                 475                 480 


Leu Leu Met Arg Pro Ile Ile Cys Ile Cys Asn Asp Gln Phe Ala Pro 
                485                 490                 495     


Ser Leu Arg Gln Leu Lys Gln Gln Ala Phe Leu Leu His Phe Pro Pro 
            500                 505                 510         


Thr Leu Pro Ser Arg Leu Val Gln Arg Leu Gln Glu Val Ser Leu Arg 
        515                 520                 525             


Gln Gly Met Arg Ala Asp Pro Gly Val Leu Ala Ala Leu Cys Glu Lys 
    530                 535                 540                 


Thr Asp Asn Asp Ile Arg Ala Cys Ile Asn Thr Leu Gln Phe Leu Tyr 
545                 550                 555                 560 


Ser Arg Gly Gln Arg Glu Leu Ser Val Arg Asp Val Gln Ala Thr Arg 
                565                 570                 575     


Val Gly Leu Lys Asp Gln Arg Arg Gly Leu Phe Ser Val Trp Gln Glu 
            580                 585                 590         


Val Phe Gln Leu Pro Arg Ala Gln Arg Arg Arg Val Gly Gln Asp Pro 
        595                 600                 605             


Ala Leu Pro Ala Asp Thr Leu Leu Leu Gly Asp Gly Asp Ala Gly Ser 
    610                 615                 620                 


Leu Thr Ser Ala Ser Gln Arg Phe Tyr Arg Val Leu His Ala Ala Ala 
625                 630                 635                 640 


Ser Ala Gly Glu His Glu Lys Val Val Gln Gly Leu Phe Asp Asn Phe 
                645                 650                 655     


Leu Arg Leu Arg Leu Arg Asp Ser Ser Leu Gly Ala Val Cys Val Ala 
            660                 665                 670         


Leu Asp Trp Leu Ala Phe Asp Asp Leu Leu Ala Gly Ala Ala His His 
        675                 680                 685             


Ser Gln Ser Phe Gln Leu Leu Arg Tyr Pro Pro Phe Leu Pro Val Ala 
    690                 695                 700                 


Phe His Val Leu Phe Ala Ser Ser His Thr Pro Arg Ile Thr Phe Pro 
705                 710                 715                 720 


Ser Ser Gln Gln Glu Ala Gln Asn Arg Met Ser Gln Met Arg Asn Leu 
                725                 730                 735     


Ile Gln Thr Leu Val Ser Gly Ile Ala Pro Ala Thr Arg Ser Arg Ala 
            740                 745                 750         


Thr Pro Gln Ala Leu Leu Leu Asp Ala Leu Cys Leu Leu Leu Asp Ile 
        755                 760                 765             


Leu Ala Pro Lys Leu Arg Pro Val Ser Thr Gln Leu Tyr Ser Thr Arg 
    770                 775                 780                 


Glu Lys Gln Gln Leu Ala Ser Leu Val Gly Thr Met Leu Ala Tyr Ser 
785                 790                 795                 800 


Leu Thr Tyr Arg Gln Glu Arg Thr Pro Asp Gly Gln Tyr Ile Tyr Arg 
                805                 810                 815     


Leu Glu Pro Asn Val Glu Glu Leu Cys Arg Phe Pro Glu Leu Pro Ala 
            820                 825                 830         


Arg Lys Pro Leu Thr Tyr Gln Thr Lys Gln Leu Ile Ala Arg Glu Ile 
        835                 840                 845             


Glu Val Glu Lys Met Arg Arg Ala Glu Ala Ser Ala Arg Val Glu Asn 
    850                 855                 860                 


Ser Pro Gln Val Asp Gly Ser Pro Pro Gly Leu Glu Gly Leu Leu Gly 
865                 870                 875                 880 


Gly Ile Gly Glu Lys Gly Val His Arg Pro Ala Pro Arg Asn His Glu 
                885                 890                 895     


Gln Arg Leu Glu His Ile Met Arg Arg Ala Ala Arg Glu Glu Gln Pro 
            900                 905                 910         


Glu Lys Asp Phe Phe Gly Arg Val Val Val Arg Ser Thr Ala Val Pro 
        915                 920                 925             


Ser Ala Gly Asp Thr Ala Pro Glu Gln Asp Ser Val Glu Arg Arg Met 
    930                 935                 940                 


Gly Thr Ala Val Gly Arg Ser Glu Val Trp Phe Arg Phe Asn Glu Gly 
945                 950                 955                 960 


Val Ser Asn Ala Val Arg Arg Ser Leu Tyr Ile Arg Asp Leu Leu 
                965                 970                 975 


<210>  1304
<211>  228
<212>  PRT
<213>  Human

<400>  1304

Met Leu Ser Arg Cys Arg Ser Gly Leu Leu His Val Leu Gly Leu Ser 
1               5                   10                  15      


Phe Leu Leu Gln Thr Arg Arg Pro Ile Leu Leu Cys Ser Pro Arg Leu 
            20                  25                  30          


Met Lys Pro Leu Val Val Phe Val Leu Gly Gly Pro Gly Ala Gly Lys 
        35                  40                  45              


Gly Thr Gln Cys Ala Arg Ile Val Glu Lys Tyr Gly Tyr Thr His Leu 
    50                  55                  60                  


Ser Ala Gly Glu Leu Leu Arg Asp Glu Arg Lys Asn Pro Asp Ser Gln 
65                  70                  75                  80  


Tyr Gly Glu Leu Ile Glu Lys Tyr Ile Lys Glu Gly Lys Ile Val Pro 
                85                  90                  95      


Val Glu Ile Thr Ile Ser Leu Leu Lys Arg Glu Met Asp Gln Thr Met 
            100                 105                 110         


Ala Ala Asn Ala Gln Lys Asn Lys Phe Leu Ile Asp Gly Phe Pro Arg 
        115                 120                 125             


Asn Gln Asp Asn Leu Gln Gly Trp Asn Lys Thr Met Asp Gly Lys Ala 
    130                 135                 140                 


Asp Val Ser Phe Val Leu Phe Phe Asp Cys Asn Asn Glu Ile Cys Ile 
145                 150                 155                 160 


Glu Arg Cys Leu Glu Arg Gly Lys Ser Ser Gly Arg Ser Asp Asp Asn 
                165                 170                 175     


Arg Glu Ser Leu Glu Lys Arg Ile Gln Thr Tyr Leu Gln Ser Thr Lys 
            180                 185                 190         


Pro Ile Ile Asp Leu Tyr Glu Glu Met Gly Lys Val Lys Lys Ile Asp 
        195                 200                 205             


Ala Ser Lys Ser Val Asp Glu Val Phe Asp Glu Val Val Gln Ile Phe 
    210                 215                 220                 


Asp Lys Glu Gly 
225             


<210>  1305
<211>  264
<212>  PRT
<213>  Human

<400>  1305

Met Ala Gly Glu Gln Lys Pro Ser Ser Asn Leu Leu Glu Gln Phe Ile 
1               5                   10                  15      


Leu Leu Ala Lys Gly Thr Ser Gly Ser Ala Leu Thr Ala Leu Ile Ser 
            20                  25                  30          


Gln Val Leu Glu Ala Pro Gly Val Tyr Val Phe Gly Glu Leu Leu Glu 
        35                  40                  45              


Leu Ala Asn Val Gln Glu Leu Ala Glu Gly Ala Asn Ala Ala Tyr Leu 
    50                  55                  60                  


Gln Leu Leu Asn Leu Phe Ala Tyr Gly Thr Tyr Pro Asp Tyr Ile Ala 
65                  70                  75                  80  


Asn Lys Glu Ser Leu Pro Glu Leu Ser Thr Ala Gln Gln Asn Lys Leu 
                85                  90                  95      


Lys His Leu Thr Ile Val Ser Leu Ala Ser Arg Met Lys Cys Ile Pro 
            100                 105                 110         


Tyr Ser Val Leu Leu Lys Asp Leu Glu Met Arg Asn Leu Arg Glu Leu 
        115                 120                 125             


Glu Asp Leu Ile Ile Glu Ala Val Tyr Thr Asp Ile Ile Gln Gly Lys 
    130                 135                 140                 


Leu Asp Gln Arg Asn Gln Leu Leu Glu Val Asp Phe Cys Ile Gly Arg 
145                 150                 155                 160 


Asp Ile Arg Lys Lys Asp Ile Asn Asn Ile Val Lys Thr Leu His Glu 
                165                 170                 175     


Trp Cys Asp Gly Cys Glu Ala Val Leu Leu Gly Ile Glu Gln Gln Val 
            180                 185                 190         


Leu Arg Ala Asn Gln Tyr Lys Glu Asn His Asn Arg Thr Gln Gln Gln 
        195                 200                 205             


Val Glu Ala Glu Val Thr Asn Ile Lys Lys Thr Leu Lys Ala Thr Ala 
    210                 215                 220                 


Ser Ser Ser Ala Gln Glu Met Glu Gln Gln Leu Ala Glu Arg Glu Cys 
225                 230                 235                 240 


Pro Pro His Ala Glu Gln Arg Gln Pro Thr Lys Lys Met Ser Lys Val 
                245                 250                 255     


Lys Gly Leu Val Ser Ser Arg His 
            260                 


<210>  1306
<211>  265
<212>  PRT
<213>  Human

<400>  1306

Met Ala Thr Leu Leu Arg Pro Val Leu Arg Arg Leu Cys Gly Leu Pro 
1               5                   10                  15      


Gly Leu Gln Arg Pro Ala Ala Glu Met Pro Leu Arg Ala Arg Ser Asp 
            20                  25                  30          


Gly Ala Gly Pro Leu Tyr Ser His His Leu Pro Thr Ser Pro Leu Gln 
        35                  40                  45              


Lys Ala Leu Leu Ala Ala Gly Ser Ala Ala Met Ala Leu Tyr Asn Pro 
    50                  55                  60                  


Tyr Arg His Asp Met Val Ala Val Leu Gly Glu Thr Thr Gly His Arg 
65                  70                  75                  80  


Thr Leu Lys Val Leu Arg Asp Gln Met Arg Arg Asp Pro Glu Gly Ala 
                85                  90                  95      


Gln Ile Leu Gln Glu Arg Pro Arg Ile Ser Thr Ser Thr Leu Asp Leu 
            100                 105                 110         


Gly Lys Leu Gln Ser Leu Pro Glu Gly Ser Leu Gly Arg Glu Tyr Leu 
        115                 120                 125             


Arg Phe Leu Asp Val Asn Arg Val Ser Pro Asp Thr Arg Ala Pro Thr 
    130                 135                 140                 


Arg Phe Val Asp Asp Glu Glu Leu Ala Tyr Val Ile Gln Arg Tyr Arg 
145                 150                 155                 160 


Glu Val His Asp Met Leu His Thr Leu Leu Gly Met Pro Thr Asn Ile 
                165                 170                 175     


Leu Gly Glu Ile Val Val Lys Trp Phe Glu Ala Val Gln Thr Gly Leu 
            180                 185                 190         


Pro Met Cys Ile Leu Gly Ala Phe Phe Gly Pro Ile Arg Leu Gly Ala 
        195                 200                 205             


Gln Ser Leu Gln Val Leu Val Ser Glu Leu Ile Pro Trp Ala Val Gln 
    210                 215                 220                 


Asn Gly Arg Arg Ala Pro Cys Val Leu Asn Leu Tyr Tyr Glu Arg Arg 
225                 230                 235                 240 


Trp Glu Gln Ser Leu Arg Ala Leu Arg Glu Glu Leu Gly Ile Thr Ala 
                245                 250                 255     


Pro Pro Met His Val Gln Gly Leu Ala 
            260                 265 


<210>  1307
<211>  153
<212>  PRT
<213>  Human

<400>  1307

Met Thr Ser Glu Ser Thr Ser Pro Pro Val Val Pro Pro Leu His Ser 
1               5                   10                  15      


Pro Lys Ser Pro Val Trp Pro Thr Phe Pro Phe His Arg Glu Gly Ser 
            20                  25                  30          


Arg Val Trp Glu Arg Gly Gly Val Pro Pro Arg Asp Leu Pro Ser Pro 
        35                  40                  45              


Leu Pro Thr Lys Arg Thr Arg Thr Tyr Ser Ala Thr Ala Arg Ala Ser 
    50                  55                  60                  


Ala Gly Pro Val Phe Lys Gly Val Cys Lys Gln Phe Ser Arg Ser Gln 
65                  70                  75                  80  


Gly His Gly Phe Ile Thr Pro Glu Asn Gly Ser Glu Asp Ile Phe Val 
                85                  90                  95      


His Val Ser Asp Ile Glu Gly Glu Tyr Val Pro Val Glu Gly Asp Glu 
            100                 105                 110         


Val Thr Tyr Lys Met Cys Pro Ile Pro Pro Lys Asn Gln Lys Phe Gln 
        115                 120                 125             


Ala Val Glu Val Val Leu Thr Gln Leu Ala Pro His Thr Pro His Glu 
    130                 135                 140                 


Thr Trp Ser Gly Gln Val Val Gly Ser 
145                 150             


<210>  1308
<211>  326
<212>  PRT
<213>  Human

<400>  1308

Met Ala Leu Ser Gly Ser Thr Pro Ala Pro Cys Trp Glu Glu Asp Glu 
1               5                   10                  15      


Cys Leu Asp Tyr Tyr Gly Met Leu Ser Leu His Arg Met Phe Glu Val 
            20                  25                  30          


Val Gly Gly Gln Leu Thr Glu Cys Glu Leu Glu Leu Leu Ala Phe Leu 
        35                  40                  45              


Leu Asp Glu Ala Pro Gly Ala Ala Gly Gly Leu Ala Arg Ala Arg Ser 
    50                  55                  60                  


Gly Leu Glu Leu Leu Leu Glu Leu Glu Arg Arg Gly Gln Cys Asp Glu 
65                  70                  75                  80  


Ser Asn Leu Arg Leu Leu Gly Gln Leu Leu Arg Val Leu Ala Arg His 
                85                  90                  95      


Asp Leu Leu Pro His Leu Ala Arg Lys Arg Arg Arg Pro Val Ser Pro 
            100                 105                 110         


Glu Arg Tyr Ser Tyr Gly Thr Ser Ser Ser Ser Lys Arg Thr Glu Gly 
        115                 120                 125             


Ser Cys Arg Arg Arg Arg Gln Ser Ser Ser Ser Ala Asn Ser Gln Gln 
    130                 135                 140                 


Gly Gln Trp Glu Thr Gly Ser Pro Pro Thr Lys Arg Gln Arg Arg Ser 
145                 150                 155                 160 


Arg Gly Arg Pro Ser Gly Gly Ala Arg Arg Arg Arg Arg Gly Ala Pro 
                165                 170                 175     


Ala Ala Pro Gln Gln Gln Ser Glu Pro Ala Arg Pro Ser Ser Glu Gly 
            180                 185                 190         


Lys Val Thr Cys Asp Ile Arg Leu Arg Val Arg Ala Glu Tyr Cys Glu 
        195                 200                 205             


His Gly Pro Ala Leu Glu Gln Gly Val Ala Ser Arg Arg Pro Gln Ala 
    210                 215                 220                 


Leu Ala Arg Gln Leu Asp Val Phe Gly Gln Ala Thr Ala Val Leu Arg 
225                 230                 235                 240 


Ser Arg Asp Leu Gly Ser Val Val Cys Asp Ile Lys Phe Ser Glu Leu 
                245                 250                 255     


Ser Tyr Leu Asp Ala Phe Trp Gly Asp Tyr Leu Ser Gly Ala Leu Leu 
            260                 265                 270         


Gln Ala Leu Arg Gly Val Phe Leu Thr Glu Ala Leu Arg Glu Ala Val 
        275                 280                 285             


Gly Arg Glu Ala Val Arg Leu Leu Val Ser Val Asp Glu Ala Asp Tyr 
    290                 295                 300                 


Glu Ala Gly Arg Arg Arg Leu Leu Leu Met Glu Glu Glu Gly Gly Arg 
305                 310                 315                 320 


Arg Pro Thr Glu Ala Ser 
                325     


<210>  1309
<211>  1143
<212>  PRT
<213>  Human

<400>  1309

Met Pro Pro Pro Arg Thr Arg Glu Gly Arg Asp Arg Arg Asp His His 
1               5                   10                  15      


Arg Ala Pro Ser Glu Glu Glu Ala Leu Glu Lys Trp Asp Trp Asn Cys 
            20                  25                  30          


Pro Glu Thr Arg Arg Leu Leu Glu Asp Ala Phe Phe Arg Glu Glu Asp 
        35                  40                  45              


Tyr Ile Arg Gln Gly Ser Glu Glu Cys Gln Lys Phe Trp Thr Phe Phe 
    50                  55                  60                  


Glu Arg Leu Gln Arg Phe Gln Asn Leu Lys Thr Ser Arg Lys Glu Glu 
65                  70                  75                  80  


Lys Asp Pro Gly Gln Pro Lys His Ser Ile Pro Ala Leu Ala Asp Leu 
                85                  90                  95      


Pro Arg Thr Tyr Asp Pro Arg Tyr Arg Ile Asn Leu Ser Val Leu Gly 
            100                 105                 110         


Pro Ala Thr Arg Gly Ser Gln Gly Leu Gly Arg His Leu Pro Ala Glu 
        115                 120                 125             


Arg Val Ala Glu Phe Arg Arg Ala Leu Leu His Tyr Leu Asp Phe Gly 
    130                 135                 140                 


Gln Lys Gln Ala Phe Gly Arg Leu Ala Lys Leu Gln Arg Glu Arg Ala 
145                 150                 155                 160 


Ala Leu Pro Ile Ala Gln Tyr Gly Asn Arg Ile Leu Gln Thr Leu Lys 
                165                 170                 175     


Glu His Gln Val Val Val Val Ala Gly Asp Thr Gly Cys Gly Lys Ser 
            180                 185                 190         


Thr Gln Val Pro Gln Tyr Leu Leu Ala Ala Gly Phe Ser His Val Ala 
        195                 200                 205             


Cys Thr Gln Pro Arg Arg Ile Ala Cys Ile Ser Leu Ala Lys Arg Val 
    210                 215                 220                 


Gly Phe Glu Ser Leu Ser Gln Tyr Gly Ser Gln Val Gly Tyr Gln Ile 
225                 230                 235                 240 


Arg Phe Glu Ser Thr Arg Ser Ala Ala Thr Lys Ile Val Phe Leu Thr 
                245                 250                 255     


Val Gly Leu Leu Leu Arg Gln Ile Gln Arg Glu Pro Ser Leu Pro Gln 
            260                 265                 270         


Tyr Glu Val Leu Ile Val Asp Glu Val His Glu Arg His Leu His Asn 
        275                 280                 285             


Asp Phe Leu Leu Gly Val Leu Gln Arg Leu Leu Pro Thr Arg Pro Asp 
    290                 295                 300                 


Leu Lys Val Ile Leu Met Ser Ala Thr Ile Asn Ile Ser Leu Phe Ser 
305                 310                 315                 320 


Ser Tyr Phe Ser Asn Ala Pro Val Val Gln Val Pro Gly Arg Leu Phe 
                325                 330                 335     


Pro Ile Thr Val Val Tyr Gln Pro Gln Glu Ala Glu Pro Thr Thr Ser 
            340                 345                 350         


Lys Ser Glu Lys Leu Asp Pro Arg Pro Phe Leu Arg Val Leu Glu Ser 
        355                 360                 365             


Ile Asp His Lys Tyr Pro Pro Glu Glu Arg Gly Asp Leu Leu Val Phe 
    370                 375                 380                 


Leu Ser Gly Met Ala Glu Ile Ser Ala Val Leu Glu Ala Ala Gln Thr 
385                 390                 395                 400 


Tyr Ala Ser His Thr Gln Arg Trp Val Val Leu Pro Leu His Ser Ala 
                405                 410                 415     


Leu Ser Val Ala Asp Gln Asp Lys Val Phe Asp Val Ala Pro Pro Gly 
            420                 425                 430         


Val Arg Lys Cys Ile Leu Ser Thr Asn Ile Ala Glu Thr Ser Val Thr 
        435                 440                 445             


Ile Asp Gly Ile Arg Phe Val Val Asp Ser Gly Lys Val Lys Glu Met 
    450                 455                 460                 


Ser Tyr Asp Pro Gln Ala Lys Leu Gln Arg Leu Gln Glu Phe Trp Ile 
465                 470                 475                 480 


Ser Gln Ala Ser Ala Glu Gln Arg Lys Gly Arg Ala Gly Arg Thr Gly 
                485                 490                 495     


Pro Gly Val Cys Phe Arg Leu Tyr Ala Glu Ser Asp Tyr Asp Ala Phe 
            500                 505                 510         


Ala Pro Tyr Pro Val Pro Glu Ile Arg Arg Val Ala Leu Asp Ser Leu 
        515                 520                 525             


Val Leu Gln Met Lys Ser Met Ser Val Gly Asp Pro Arg Thr Phe Pro 
    530                 535                 540                 


Phe Ile Glu Pro Pro Pro Pro Ala Ser Leu Glu Thr Ala Ile Leu Tyr 
545                 550                 555                 560 


Leu Arg Asp Gln Gly Ala Leu Asp Ser Ser Glu Ala Leu Thr Pro Ile 
                565                 570                 575     


Gly Ser Leu Leu Ala Gln Leu Pro Val Asp Val Val Ile Gly Lys Met 
            580                 585                 590         


Leu Ile Leu Gly Ser Met Phe Ser Leu Val Glu Pro Val Leu Thr Ile 
        595                 600                 605             


Ala Ala Ala Leu Ser Val Gln Ser Pro Phe Thr Arg Ser Ala Gln Ser 
    610                 615                 620                 


Ser Pro Glu Cys Ala Ala Ala Arg Arg Pro Leu Glu Ser Asp Gln Gly 
625                 630                 635                 640 


Asp Pro Phe Thr Leu Phe Asn Val Phe Asn Ala Trp Val Gln Val Lys 
                645                 650                 655     


Ser Glu Arg Ser Arg Asn Ser Arg Lys Trp Cys Arg Arg Arg Gly Ile 
            660                 665                 670         


Glu Glu His Arg Leu Tyr Glu Met Ala Asn Leu Arg Arg Gln Phe Lys 
        675                 680                 685             


Glu Leu Leu Glu Asp His Gly Leu Leu Ala Gly Ala Gln Ala Ala Gln 
    690                 695                 700                 


Val Gly Asp Ser Tyr Ser Arg Leu Gln Gln Arg Arg Glu Arg Arg Ala 
705                 710                 715                 720 


Leu His Gln Leu Lys Arg Gln His Glu Glu Gly Ala Gly Arg Arg Arg 
                725                 730                 735     


Lys Val Leu Arg Leu Gln Glu Glu Gln Asp Gly Gly Ser Ser Asp Glu 
            740                 745                 750         


Asp Arg Ala Gly Pro Ala Pro Pro Gly Ala Ser Asp Gly Val Asp Ile 
        755                 760                 765             


Gln Asp Val Lys Phe Lys Leu Arg His Asp Leu Ala Gln Leu Gln Ala 
    770                 775                 780                 


Ala Ala Ser Ser Ala Gln Asp Leu Ser Arg Glu Gln Leu Ala Leu Leu 
785                 790                 795                 800 


Lys Leu Val Leu Gly Arg Gly Leu Tyr Pro Gln Leu Ala Val Pro Asp 
                805                 810                 815     


Ala Phe Asn Ser Ser Arg Lys Asp Ser Asp Gln Ile Phe His Thr Gln 
            820                 825                 830         


Ala Lys Gln Gly Ala Val Leu His Pro Thr Cys Val Phe Ala Gly Ser 
        835                 840                 845             


Pro Glu Val Leu His Ala Gln Glu Leu Glu Ala Ser Asn Cys Asp Gly 
    850                 855                 860                 


Ser Arg Asp Asp Lys Asp Lys Met Ser Ser Lys His Gln Leu Leu Ser 
865                 870                 875                 880 


Phe Val Ser Leu Leu Glu Thr Asn Lys Pro Tyr Leu Val Asn Cys Val 
                885                 890                 895     


Arg Ile Pro Ala Leu Gln Ser Leu Leu Leu Phe Ser Arg Ser Leu Asp 
            900                 905                 910         


Thr Asn Gly Asp Cys Ser Arg Leu Val Ala Asp Gly Trp Leu Glu Leu 
        915                 920                 925             


Gln Leu Ala Asp Ser Glu Ser Ala Ile Arg Leu Leu Ala Ala Ser Leu 
    930                 935                 940                 


Arg Leu Arg Ala Arg Trp Glu Ser Ala Leu Asp Arg Gln Leu Ala His 
945                 950                 955                 960 


Gln Ala Gln Gln Gln Leu Glu Glu Glu Glu Glu Asp Thr Pro Val Ser 
                965                 970                 975     


Pro Lys Glu Val Ala Thr Leu Ser Lys Glu Leu Leu Gln Phe Thr Ala 
            980                 985                 990         


Ser Lys Ile Pro Tyr Ser Leu Arg  Arg Leu Thr Gly Leu  Glu Val Gln 
        995                 1000                 1005             


Asn Met  Tyr Val Gly Pro Gln  Thr Ile Pro Ala Thr  Pro His Leu 
    1010                 1015                 1020             


Pro Gly  Leu Phe Gly Ser Ser  Thr Leu Ser Pro His  Pro Thr Lys 
    1025                 1030                 1035             


Gly Gly  Tyr Ala Val Thr Asp  Phe Leu Thr Tyr Asn  Cys Leu Thr 
    1040                 1045                 1050             


Asn Asp  Thr Asp Leu Tyr Ser  Asp Cys Leu Arg Thr  Phe Trp Thr 
    1055                 1060                 1065             


Cys Pro  His Cys Gly Leu His  Ala Pro Leu Thr Pro  Leu Glu Arg 
    1070                 1075                 1080             


Ile Ala  His Glu Asn Thr Cys  Pro Gln Ala Pro Gln  Asp Gly Pro 
    1085                 1090                 1095             


Pro Gly  Ala Glu Glu Ala Ala  Leu Glu Thr Leu Gln  Lys Thr Ser 
    1100                 1105                 1110             


Val Leu  Gln Arg Pro Tyr His  Cys Glu Ala Cys Gly  Lys Asp Phe 
    1115                 1120                 1125             


Leu Phe  Thr Pro Thr Glu Val  Leu Arg His Arg Lys  Gln His Val 
    1130                 1135                 1140             


<210>  1310
<211>  285
<212>  PRT
<213>  Human

<400>  1310

Met Asn Arg Leu Pro Asp Asp Tyr Asp Pro Tyr Ala Val Glu Glu Pro 
1               5                   10                  15      


Ser Asp Glu Glu Pro Ala Leu Ser Ser Ser Glu Asp Glu Val Asp Val 
            20                  25                  30          


Leu Leu His Gly Thr Pro Asp Gln Lys Arg Lys Leu Ile Arg Glu Cys 
        35                  40                  45              


Leu Thr Gly Glu Ser Glu Ser Ser Ser Glu Asp Glu Phe Glu Lys Glu 
    50                  55                  60                  


Met Glu Ala Glu Leu Asn Ser Thr Met Lys Thr Met Glu Asp Lys Leu 
65                  70                  75                  80  


Ser Ser Leu Gly Thr Gly Ser Ser Ser Gly Asn Gly Lys Val Ala Thr 
                85                  90                  95      


Ala Pro Thr Arg Tyr Tyr Asp Asp Ile Tyr Phe Asp Ser Asp Ser Glu 
            100                 105                 110         


Asp Glu Asp Arg Ala Val Gln Val Thr Lys Lys Lys Lys Lys Lys Gln 
        115                 120                 125             


His Lys Ile Pro Thr Asn Asp Glu Leu Leu Tyr Asp Pro Glu Lys Asp 
    130                 135                 140                 


Asn Arg Asp Gln Ala Trp Val Asp Ala Gln Arg Arg Gly Tyr His Gly 
145                 150                 155                 160 


Leu Gly Pro Gln Arg Ser Arg Gln Gln Gln Pro Val Pro Asn Ser Asp 
                165                 170                 175     


Ala Val Leu Asn Cys Pro Ala Cys Met Thr Thr Leu Cys Leu Asp Cys 
            180                 185                 190         


Gln Arg His Glu Ser Tyr Lys Thr Gln Tyr Arg Ala Met Phe Val Met 
        195                 200                 205             


Asn Cys Ser Ile Asn Lys Glu Glu Val Leu Arg Tyr Lys Ala Ser Glu 
    210                 215                 220                 


Asn Arg Lys Lys Arg Arg Val His Lys Lys Met Arg Ser Asn Arg Glu 
225                 230                 235                 240 


Asp Ala Ala Glu Lys Ala Glu Thr Asp Val Glu Glu Ile Tyr His Pro 
                245                 250                 255     


Val Met Cys Thr Glu Cys Ser Thr Glu Val Ala Val Tyr Asp Lys Asp 
            260                 265                 270         


Glu Val Phe His Phe Phe Asn Val Leu Ala Ser His Ser 
        275                 280                 285 


<210>  1311
<211>  670
<212>  PRT
<213>  Human

<400>  1311

Met Glu Glu Phe Arg Arg Ser Tyr Ser Arg Leu Cys Arg Glu Ser Gly 
1               5                   10                  15      


Ala Glu Pro Gln Glu Ala Val Leu Gln Gln Leu His Gln Leu Pro Arg 
            20                  25                  30          


Gly Arg Leu Asp Leu Ala Thr Gln Ser Leu Thr Val Glu Thr Cys Arg 
        35                  40                  45              


Ala Leu Gly Lys Leu Leu Pro Arg Glu Thr Leu Cys Thr Glu Leu Val 
    50                  55                  60                  


Leu Ser Asp Cys Met Leu Ser Glu Glu Gly Ala Thr Leu Leu Leu Arg 
65                  70                  75                  80  


Gly Leu Cys Ala Asn Thr Val Leu Arg Phe Leu Asp Leu Lys Gly Asn 
                85                  90                  95      


Asn Leu Arg Ala Ala Gly Ala Glu Ala Leu Gly Lys Leu Leu Gln Gln 
            100                 105                 110         


Asn Lys Ser Ile Gln Ser Leu Thr Leu Glu Trp Asn Ser Leu Gly Thr 
        115                 120                 125             


Trp Asp Asp Ala Phe Ala Thr Phe Cys Gly Gly Leu Ala Ala Asn Gly 
    130                 135                 140                 


Ala Leu Gln Arg Leu Asp Leu Arg Asn Asn Gln Ile Ser His Lys Gly 
145                 150                 155                 160 


Ala Glu Glu Leu Ala Leu Ala Leu Lys Gly Asn Thr Thr Leu Gln Gln 
                165                 170                 175     


Leu Asp Leu Arg Trp Asn Asn Val Gly Leu Leu Gly Gly Arg Ala Leu 
            180                 185                 190         


Met Asn Cys Leu Pro Ser Asn Arg Thr Leu Trp Arg Leu Asp Leu Ala 
        195                 200                 205             


Gly Asn Asn Ile Pro Gly Asp Val Leu Arg Ala Val Glu Gln Ala Met 
    210                 215                 220                 


Gly His Ser Gln Asp Arg Leu Thr Thr Phe Gln Glu Asn Gln Ala Arg 
225                 230                 235                 240 


Thr His Val Leu Ser Lys Glu Val Gln His Leu Arg Glu Glu Lys Ser 
                245                 250                 255     


Lys Gln Phe Leu Asp Leu Met Glu Thr Ile Asp Lys Gln Arg Glu Glu 
            260                 265                 270         


Met Ala Lys Ser Ser Arg Ala Ser Ala Ala Arg Val Gly Gln Leu Gln 
        275                 280                 285             


Glu Ala Leu Asn Glu Arg His Ser Ile Ile Asn Ala Leu Lys Ala Lys 
    290                 295                 300                 


Leu Gln Met Thr Glu Ala Ala Leu Ala Leu Ser Glu Gln Lys Ala Gln 
305                 310                 315                 320 


Asp Leu Gly Glu Leu Leu Ala Thr Ala Glu Gln Glu Gln Leu Ser Leu 
                325                 330                 335     


Ser Gln Arg Gln Ala Lys Glu Leu Lys Leu Glu Gln Gln Glu Ala Ala 
            340                 345                 350         


Glu Arg Glu Ser Lys Leu Leu Arg Asp Leu Ser Ala Ala Asn Glu Lys 
        355                 360                 365             


Asn Leu Leu Leu Gln Asn Gln Val Asp Glu Leu Glu Arg Lys Phe Arg 
    370                 375                 380                 


Cys Gln Gln Glu Gln Leu Phe Gln Thr Arg Gln Glu Met Thr Ser Met 
385                 390                 395                 400 


Ser Ala Glu Leu Lys Met Arg Ala Ile Gln Ala Glu Glu Arg Leu Asp 
                405                 410                 415     


Met Glu Lys Arg Arg Cys Arg Gln Ser Leu Glu Asp Ser Glu Ser Leu 
            420                 425                 430         


Arg Ile Lys Glu Val Glu His Met Thr Arg His Leu Glu Glu Ser Glu 
        435                 440                 445             


Lys Ala Met Gln Glu Arg Val Gln Arg Leu Glu Ala Ala Arg Leu Ser 
    450                 455                 460                 


Leu Glu Glu Glu Leu Ser Arg Val Lys Ala Ala Ala Leu Ser Glu Arg 
465                 470                 475                 480 


Gly Gln Ala Glu Glu Glu Leu Ile Lys Ala Lys Ser Gln Ala Arg Leu 
                485                 490                 495     


Glu Glu Gln Gln Arg Leu Ala His Leu Glu Asp Lys Leu Arg Leu Leu 
            500                 505                 510         


Ala Gln Ala Arg Asp Glu Ala Gln Gly Ala Cys Leu Gln Gln Lys Gln 
        515                 520                 525             


Val Val Ala Glu Ala Gln Thr Arg Val Ser Gln Leu Gly Leu Gln Val 
    530                 535                 540                 


Glu Gly Leu Arg Arg Arg Leu Glu Glu Leu Gln Gln Glu Leu Ser Leu 
545                 550                 555                 560 


Lys Asp Gln Glu Arg Val Ala Glu Val Ser Arg Val Arg Val Glu Leu 
                565                 570                 575     


Gln Glu Gln Asn Gly Arg Leu Gln Ala Glu Leu Ala Ala Gln Glu Ala 
            580                 585                 590         


Leu Arg Glu Lys Ala Ala Ala Leu Glu Arg Gln Leu Lys Val Met Ala 
        595                 600                 605             


Ser Asp His Arg Glu Ala Leu Leu Asp Arg Glu Ser Glu Asn Ala Ser 
    610                 615                 620                 


Leu Arg Glu Lys Leu Arg Leu Arg Glu Ala Glu Ile Ala Arg Ile Arg 
625                 630                 635                 640 


Asp Glu Glu Ala Gln Arg Ala Ser Phe Leu Gln Asn Ala Val Leu Ala 
                645                 650                 655     


Tyr Val Gln Ala Ser Pro Val Arg Thr Leu Ser Pro Pro Lys 
            660                 665                 670 


<210>  1312
<211>  257
<212>  PRT
<213>  Human

<400>  1312

Met Ala Thr Asn Phe Leu Ala His Glu Lys Ile Trp Phe Asp Lys Phe 
1               5                   10                  15      


Lys Tyr Asp Asp Ala Glu Arg Arg Phe Tyr Glu Gln Met Asn Gly Pro 
            20                  25                  30          


Val Ala Gly Ala Ser Arg Gln Ser Ser Gly Pro Gly Ala Ser Ser Gly 
        35                  40                  45              


Thr Ser Gly Asp His Gly Glu Leu Val Val Arg Ile Ala Ser Leu Glu 
    50                  55                  60                  


Val Glu Asn Gln Ser Leu Arg Gly Val Val Gln Glu Leu Gln Gln Ala 
65                  70                  75                  80  


Ile Ser Lys Leu Glu Ala Arg Leu Asn Val Leu Glu Lys Ser Ser Pro 
                85                  90                  95      


Gly His Arg Ala Thr Ala Pro Gln Thr Gln His Val Ser Pro Met Arg 
            100                 105                 110         


Gln Val Glu Pro Pro Ala Lys Lys Pro Ala Thr Pro Ala Glu Asp Asp 
        115                 120                 125             


Glu Asp Asp Asp Ile Asp Leu Phe Gly Ser Asp Asn Glu Glu Glu Asp 
    130                 135                 140                 


Lys Glu Ala Ala Gln Leu Arg Glu Glu Arg Leu Arg Gln Tyr Ala Glu 
145                 150                 155                 160 


Lys Lys Ala Lys Lys Pro Ala Leu Val Ala Lys Ser Ser Ile Leu Leu 
                165                 170                 175     


Asp Val Lys Pro Trp Asp Asp Glu Thr Asp Met Ala Gln Leu Glu Ala 
            180                 185                 190         


Cys Val Arg Ser Ile Gln Leu Asp Gly Leu Val Trp Gly Ala Ser Lys 
        195                 200                 205             


Leu Val Pro Val Gly Tyr Gly Ile Arg Lys Leu Gln Ile Gln Cys Val 
    210                 215                 220                 


Val Glu Asp Asp Lys Val Gly Thr Asp Leu Leu Glu Glu Glu Ile Thr 
225                 230                 235                 240 


Lys Phe Glu Glu His Val Gln Ser Val Asp Ile Ala Ala Phe Asn Lys 
                245                 250                 255     


Ile 
    


<210>  1313
<211>  258
<212>  PRT
<213>  Human

<400>  1313

Met Ala Ala Ala Ala Ala Ala Ala Gly Asp Ser Asp Ser Trp Asp Ala 
1               5                   10                  15      


Asp Ala Phe Ser Val Glu Asp Pro Val Arg Lys Val Gly Gly Gly Gly 
            20                  25                  30          


Thr Ala Gly Gly Asp Arg Trp Glu Gly Glu Asp Glu Asp Glu Asp Val 
        35                  40                  45              


Lys Asp Asn Trp Asp Asp Asp Asp Asp Glu Lys Lys Glu Glu Ala Glu 
    50                  55                  60                  


Val Lys Pro Glu Val Lys Ile Ser Glu Lys Lys Lys Ile Ala Glu Lys 
65                  70                  75                  80  


Ile Lys Glu Lys Glu Arg Gln Gln Lys Lys Arg Gln Glu Glu Ile Lys 
                85                  90                  95      


Lys Arg Leu Glu Glu Pro Glu Glu Pro Lys Val Leu Thr Pro Glu Glu 
            100                 105                 110         


Gln Leu Ala Asp Lys Leu Arg Leu Lys Lys Leu Gln Glu Glu Ser Asp 
        115                 120                 125             


Leu Glu Leu Ala Lys Glu Thr Phe Gly Val Asn Asn Ala Val Tyr Gly 
    130                 135                 140                 


Ile Asp Ala Met Asn Pro Ser Ser Arg Asp Asp Phe Thr Glu Phe Gly 
145                 150                 155                 160 


Lys Leu Leu Lys Asp Lys Ile Thr Gln Tyr Glu Lys Ser Leu Tyr Tyr 
                165                 170                 175     


Ala Ser Phe Leu Glu Val Leu Val Arg Asp Val Cys Ile Ser Leu Glu 
            180                 185                 190         


Ile Asp Asp Leu Lys Lys Ile Thr Asn Ser Leu Thr Val Leu Cys Ser 
        195                 200                 205             


Glu Lys Gln Lys Gln Glu Lys Gln Ser Lys Ala Lys Lys Lys Lys Lys 
    210                 215                 220                 


Gly Val Val Pro Gly Gly Gly Leu Lys Ala Thr Met Lys Asp Asp Leu 
225                 230                 235                 240 


Ala Asp Tyr Gly Gly Tyr Asp Gly Gly Tyr Val Gln Asp Tyr Glu Asp 
                245                 250                 255     


Phe Met 
        


<210>  1314
<211>  570
<212>  PRT
<213>  Human

<400>  1314

Met Ser Glu Gln Ser Ile Cys Gln Ala Arg Ala Ala Val Met Val Tyr 
1               5                   10                  15      


Asp Asp Ala Asn Lys Lys Trp Val Pro Ala Gly Gly Ser Thr Gly Phe 
            20                  25                  30          


Ser Arg Val His Ile Tyr His His Thr Gly Asn Asn Thr Phe Arg Val 
        35                  40                  45              


Val Gly Arg Lys Ile Gln Asp His Gln Val Val Ile Asn Cys Ala Ile 
    50                  55                  60                  


Pro Lys Gly Leu Lys Tyr Asn Gln Ala Thr Gln Thr Phe His Gln Trp 
65                  70                  75                  80  


Arg Asp Ala Arg Gln Val Tyr Gly Leu Asn Phe Gly Ser Lys Glu Asp 
                85                  90                  95      


Ala Asn Val Phe Ala Ser Ala Met Met His Ala Leu Glu Val Leu Asn 
            100                 105                 110         


Ser Gln Glu Thr Gly Pro Thr Leu Pro Arg Gln Asn Ser Gln Leu Pro 
        115                 120                 125             


Ala Gln Val Gln Asn Gly Pro Ser Gln Glu Glu Leu Glu Ile Gln Arg 
    130                 135                 140                 


Arg Gln Leu Gln Glu Gln Gln Arg Gln Lys Glu Leu Glu Arg Glu Arg 
145                 150                 155                 160 


Leu Glu Arg Glu Arg Met Glu Arg Glu Arg Leu Glu Arg Glu Arg Leu 
                165                 170                 175     


Glu Arg Glu Arg Leu Glu Arg Glu Arg Leu Glu Gln Glu Gln Leu Glu 
            180                 185                 190         


Arg Glu Arg Gln Glu Arg Glu Arg Gln Glu Arg Leu Glu Arg Gln Glu 
        195                 200                 205             


Arg Leu Glu Arg Gln Glu Arg Leu Glu Arg Gln Glu Arg Leu Asp Arg 
    210                 215                 220                 


Glu Arg Gln Glu Arg Gln Glu Arg Glu Arg Leu Glu Arg Leu Glu Arg 
225                 230                 235                 240 


Glu Arg Gln Glu Arg Glu Arg Gln Glu Gln Leu Glu Arg Glu Gln Leu 
                245                 250                 255     


Glu Trp Glu Arg Glu Arg Arg Ile Ser Ser Ala Ala Ala Pro Ala Ser 
            260                 265                 270         


Val Glu Thr Pro Leu Asn Ser Val Leu Gly Asp Ser Ser Ala Ser Glu 
        275                 280                 285             


Pro Gly Leu Gln Ala Ala Ser Gln Pro Ala Glu Thr Pro Ser Gln Gln 
    290                 295                 300                 


Gly Ile Val Leu Gly Pro Leu Ala Pro Pro Pro Pro Pro Pro Leu Pro 
305                 310                 315                 320 


Pro Gly Pro Ala Gln Ala Ser Val Ala Leu Pro Pro Pro Pro Gly Pro 
                325                 330                 335     


Pro Pro Pro Pro Pro Leu Pro Ser Thr Gly Pro Pro Pro Pro Pro Pro 
            340                 345                 350         


Pro Pro Pro Leu Pro Asn Gln Val Pro Pro Pro Pro Pro Pro Pro Pro 
        355                 360                 365             


Ala Pro Pro Leu Pro Ala Ser Gly Phe Phe Leu Ala Ser Met Ser Glu 
    370                 375                 380                 


Asp Asn Arg Pro Leu Thr Gly Leu Ala Ala Ala Ile Ala Gly Ala Lys 
385                 390                 395                 400 


Leu Arg Lys Val Ser Arg Met Glu Asp Thr Ser Phe Pro Ser Gly Gly 
                405                 410                 415     


Asn Ala Ile Gly Val Asn Ser Ala Ser Ser Lys Thr Asp Thr Gly Arg 
            420                 425                 430         


Gly Asn Gly Pro Leu Pro Leu Gly Gly Ser Gly Leu Met Glu Glu Met 
        435                 440                 445             


Ser Ala Leu Leu Ala Arg Arg Arg Arg Ile Ala Glu Lys Gly Ser Thr 
    450                 455                 460                 


Ile Glu Thr Glu Gln Lys Glu Asp Lys Gly Glu Asp Ser Glu Pro Val 
465                 470                 475                 480 


Thr Ser Lys Ala Ser Ser Thr Ser Thr Pro Glu Pro Thr Arg Lys Pro 
                485                 490                 495     


Trp Glu Arg Thr Asn Thr Met Asn Gly Ser Lys Ser Pro Val Ile Ser 
            500                 505                 510         


Arg Pro Lys Ser Thr Pro Leu Ser Gln Pro Ser Ala Asn Gly Val Gln 
        515                 520                 525             


Thr Glu Gly Leu Asp Tyr Asp Arg Leu Lys Gln Asp Ile Leu Asp Glu 
    530                 535                 540                 


Met Arg Lys Glu Leu Thr Lys Leu Lys Glu Glu Leu Ile Asp Ala Ile 
545                 550                 555                 560 


Arg Gln Glu Leu Ser Lys Ser Asn Thr Ala 
                565                 570 


<210>  1315
<211>  434
<212>  PRT
<213>  Human

<400>  1315

Met Ser Ile Leu Lys Ile His Ala Arg Glu Ile Phe Asp Ser Arg Gly 
1               5                   10                  15      


Asn Pro Thr Val Glu Val Asp Leu Phe Thr Ser Lys Gly Leu Phe Arg 
            20                  25                  30          


Ala Ala Val Pro Ser Gly Ala Ser Thr Gly Ile Tyr Glu Ala Leu Glu 
        35                  40                  45              


Leu Arg Asp Asn Asp Lys Thr Arg Tyr Met Gly Lys Gly Val Ser Lys 
    50                  55                  60                  


Ala Val Glu His Ile Asn Lys Thr Ile Ala Pro Ala Leu Val Ser Lys 
65                  70                  75                  80  


Lys Leu Asn Val Thr Glu Gln Glu Lys Ile Asp Lys Leu Met Ile Glu 
                85                  90                  95      


Met Asp Gly Thr Glu Asn Lys Ser Lys Phe Gly Ala Asn Ala Ile Leu 
            100                 105                 110         


Gly Val Ser Leu Ala Val Cys Lys Ala Gly Ala Val Glu Lys Gly Val 
        115                 120                 125             


Pro Leu Tyr Arg His Ile Ala Asp Leu Ala Gly Asn Ser Glu Val Ile 
    130                 135                 140                 


Leu Pro Val Pro Ala Phe Asn Val Ile Asn Gly Gly Ser His Ala Gly 
145                 150                 155                 160 


Asn Lys Leu Ala Met Gln Glu Phe Met Ile Leu Pro Val Gly Ala Ala 
                165                 170                 175     


Asn Phe Arg Glu Ala Met Arg Ile Gly Ala Glu Val Tyr His Asn Leu 
            180                 185                 190         


Lys Asn Val Ile Lys Glu Lys Tyr Gly Lys Asp Ala Thr Asn Val Gly 
        195                 200                 205             


Asp Glu Gly Gly Phe Ala Pro Asn Ile Leu Glu Asn Lys Glu Gly Leu 
    210                 215                 220                 


Glu Leu Leu Lys Thr Ala Ile Gly Lys Ala Gly Tyr Thr Asp Lys Val 
225                 230                 235                 240 


Val Ile Gly Met Asp Val Ala Ala Ser Glu Phe Phe Arg Ser Gly Lys 
                245                 250                 255     


Tyr Asp Leu Asp Phe Lys Ser Pro Asp Asp Pro Ser Arg Tyr Ile Ser 
            260                 265                 270         


Pro Asp Gln Leu Ala Asp Leu Tyr Lys Ser Phe Ile Lys Asp Tyr Pro 
        275                 280                 285             


Val Val Ser Ile Glu Asp Pro Phe Asp Gln Asp Asp Trp Gly Ala Trp 
    290                 295                 300                 


Gln Lys Phe Thr Ala Ser Ala Gly Ile Gln Val Val Gly Asp Asp Leu 
305                 310                 315                 320 


Thr Val Thr Asn Pro Lys Arg Ile Ala Lys Ala Val Asn Glu Lys Ser 
                325                 330                 335     


Cys Asn Cys Leu Leu Leu Lys Val Asn Gln Ile Gly Ser Val Thr Glu 
            340                 345                 350         


Ser Leu Gln Ala Cys Lys Leu Ala Gln Ala Asn Gly Trp Gly Val Met 
        355                 360                 365             


Val Ser His Arg Ser Gly Glu Thr Glu Asp Thr Phe Ile Ala Asp Leu 
    370                 375                 380                 


Val Val Gly Leu Cys Thr Gly Gln Ile Lys Thr Gly Ala Pro Cys Arg 
385                 390                 395                 400 


Ser Glu Arg Leu Ala Lys Tyr Asn Gln Leu Leu Arg Ile Glu Glu Glu 
                405                 410                 415     


Leu Gly Ser Lys Ala Lys Phe Ala Gly Arg Asn Phe Arg Asn Pro Leu 
            420                 425                 430         


Ala Lys 
        


<210>  1316
<211>  650
<212>  PRT
<213>  Human

<400>  1316

Met Ala Ser Asn Met Asp Arg Glu Met Ile Leu Ala Asp Phe Gln Ala 
1               5                   10                  15      


Cys Thr Gly Ile Glu Asn Ile Asp Glu Ala Ile Thr Leu Leu Glu Gln 
            20                  25                  30          


Asn Asn Trp Asp Leu Val Ala Ala Ile Asn Gly Val Ile Pro Gln Glu 
        35                  40                  45              


Asn Gly Ile Leu Gln Ser Glu Tyr Gly Gly Glu Thr Ile Pro Gly Pro 
    50                  55                  60                  


Ala Phe Asn Pro Ala Ser His Pro Ala Ser Ala Pro Thr Ser Ser Ser 
65                  70                  75                  80  


Ser Ser Ala Phe Arg Pro Val Met Pro Ser Arg Gln Ile Val Glu Arg 
                85                  90                  95      


Gln Pro Arg Met Leu Asp Phe Arg Val Glu Tyr Arg Asp Arg Asn Val 
            100                 105                 110         


Asp Val Val Leu Glu Asp Thr Cys Thr Val Gly Glu Ile Lys Gln Ile 
        115                 120                 125             


Leu Glu Asn Glu Leu Gln Ile Pro Val Ser Lys Met Leu Leu Lys Gly 
    130                 135                 140                 


Trp Lys Thr Gly Asp Val Glu Asp Ser Thr Val Leu Lys Ser Leu His 
145                 150                 155                 160 


Leu Pro Lys Asn Asn Ser Leu Tyr Val Leu Thr Pro Asp Leu Pro Pro 
                165                 170                 175     


Pro Ser Ser Ser Ser His Ala Gly Ala Leu Gln Glu Ser Leu Asn Gln 
            180                 185                 190         


Asn Phe Met Leu Ile Ile Thr His Arg Glu Val Gln Arg Glu Tyr Asn 
        195                 200                 205             


Leu Asn Phe Ser Gly Ser Ser Thr Ile Gln Glu Val Lys Arg Asn Val 
    210                 215                 220                 


Tyr Asp Leu Thr Ser Ile Pro Val Arg His Gln Leu Trp Glu Gly Trp 
225                 230                 235                 240 


Pro Thr Ser Ala Thr Asp Asp Ser Met Cys Leu Ala Glu Ser Gly Leu 
                245                 250                 255     


Ser Tyr Pro Cys His Arg Leu Thr Val Gly Arg Arg Ser Ser Pro Ala 
            260                 265                 270         


Gln Thr Arg Glu Gln Ser Glu Glu Gln Ile Thr Asp Val His Met Val 
        275                 280                 285             


Ser Asp Ser Asp Gly Asp Asp Phe Glu Asp Ala Thr Glu Phe Gly Val 
    290                 295                 300                 


Asp Asp Gly Glu Val Phe Gly Met Ala Ser Ser Ala Leu Arg Lys Ser 
305                 310                 315                 320 


Pro Met Met Pro Glu Asn Ala Glu Asn Glu Gly Asp Ala Leu Leu Gln 
                325                 330                 335     


Phe Thr Ala Glu Phe Ser Ser Arg Tyr Gly Asp Cys His Pro Val Phe 
            340                 345                 350         


Phe Ile Gly Ser Leu Glu Ala Ala Phe Gln Glu Ala Phe Tyr Val Lys 
        355                 360                 365             


Ala Arg Asp Arg Lys Leu Leu Ala Ile Tyr Leu His His Asp Glu Ser 
    370                 375                 380                 


Val Leu Thr Asn Val Phe Cys Ser Gln Met Leu Cys Ala Glu Ser Ile 
385                 390                 395                 400 


Val Ser Tyr Leu Ser Gln Asn Phe Ile Thr Trp Ala Trp Asp Leu Thr 
                405                 410                 415     


Lys Asp Ser Asn Arg Ala Arg Phe Leu Thr Met Cys Asn Arg His Phe 
            420                 425                 430         


Gly Ser Val Val Ala Gln Thr Ile Arg Thr Gln Lys Thr Asp Gln Phe 
        435                 440                 445             


Pro Leu Phe Leu Ile Ile Met Gly Lys Arg Ser Ser Asn Glu Val Leu 
    450                 455                 460                 


Asn Val Ile Gln Gly Asn Thr Thr Val Asp Glu Leu Met Met Arg Leu 
465                 470                 475                 480 


Met Ala Ala Met Glu Ile Phe Thr Ala Gln Gln Gln Glu Asp Ile Lys 
                485                 490                 495     


Asp Glu Asp Glu Arg Glu Ala Arg Glu Asn Val Lys Arg Glu Gln Asp 
            500                 505                 510         


Glu Ala Tyr Arg Leu Ser Leu Glu Ala Asp Arg Ala Lys Arg Glu Ala 
        515                 520                 525             


His Glu Arg Glu Met Ala Glu Gln Phe Arg Leu Glu Gln Ile Arg Lys 
    530                 535                 540                 


Glu Gln Glu Glu Glu Arg Glu Ala Ile Arg Leu Ser Leu Glu Gln Ala 
545                 550                 555                 560 


Leu Pro Pro Glu Pro Lys Glu Glu Asn Ala Glu Pro Val Ser Lys Leu 
                565                 570                 575     


Arg Ile Arg Thr Pro Ser Gly Glu Phe Leu Glu Arg Arg Phe Leu Ala 
            580                 585                 590         


Ser Asn Lys Leu Gln Ile Val Phe Asp Phe Val Ala Ser Lys Gly Phe 
        595                 600                 605             


Pro Trp Asp Glu Tyr Lys Leu Leu Ser Thr Phe Pro Arg Arg Asp Val 
    610                 615                 620                 


Thr Gln Leu Asp Pro Asn Lys Ser Leu Leu Glu Val Lys Leu Phe Pro 
625                 630                 635                 640 


Gln Glu Thr Leu Phe Leu Glu Ala Lys Glu 
                645                 650 


<210>  1317
<211>  144
<212>  PRT
<213>  Human

<400>  1317

Met Tyr Ser Glu Ile Gln Arg Glu Arg Ala Asp Ile Gly Gly Leu Met 
1               5                   10                  15      


Ala Arg Pro Glu Tyr Arg Glu Trp Asn Pro Glu Leu Ile Lys Pro Lys 
            20                  25                  30          


Lys Leu Leu Asn Pro Val Lys Ala Ser Arg Ser His Gln Glu Leu His 
        35                  40                  45              


Arg Glu Leu Leu Met Asn His Arg Arg Gly Leu Gly Val Asp Ser Lys 
    50                  55                  60                  


Pro Glu Leu Gln Arg Val Leu Glu His Arg Arg Arg Asn Gln Leu Ile 
65                  70                  75                  80  


Lys Lys Lys Lys Glu Glu Leu Glu Ala Lys Arg Leu Gln Cys Pro Phe 
                85                  90                  95      


Glu Gln Glu Leu Leu Arg Arg Gln Gln Arg Leu Asn Gln Leu Glu Lys 
            100                 105                 110         


Pro Pro Glu Lys Glu Glu Asp His Ala Pro Glu Phe Ile Lys Val Arg 
        115                 120                 125             


Glu Asn Leu Arg Arg Ile Ala Thr Leu Thr Ser Glu Glu Arg Glu Leu 
    130                 135                 140                 


<210>  1318
<211>  138
<212>  PRT
<213>  Human

<400>  1318

Met Ala Glu Leu Gln Gln Leu Arg Val Gln Glu Ala Val Glu Ser Met 
1               5                   10                  15      


Val Lys Ser Leu Glu Arg Glu Asn Ile Arg Lys Met Gln Gly Leu Met 
            20                  25                  30          


Phe Arg Cys Ser Ala Ser Cys Cys Glu Asp Ser Gln Ala Ser Met Lys 
        35                  40                  45              


Gln Val His Gln Cys Ile Glu Arg Cys His Val Pro Leu Ala Gln Ala 
    50                  55                  60                  


Gln Ala Leu Val Thr Ser Glu Leu Glu Lys Phe Gln Asp Arg Leu Ala 
65                  70                  75                  80  


Arg Cys Thr Met His Cys Asn Asp Lys Ala Lys Asp Ser Ile Asp Ala 
                85                  90                  95      


Gly Ser Lys Glu Leu Gln Val Lys Gln Gln Leu Asp Ser Cys Val Thr 
            100                 105                 110         


Lys Cys Val Asp Asp His Met His Leu Ile Pro Thr Met Thr Lys Lys 
        115                 120                 125             


Met Lys Glu Ala Leu Leu Ser Ile Gly Lys 
    130                 135             


<210>  1319
<211>  697
<212>  PRT
<213>  Human

<400>  1319

Met Ala Cys Glu Ile Met Pro Leu Gln Ser Ser Gln Glu Asp Glu Arg 
1               5                   10                  15      


Pro Leu Ser Pro Phe Tyr Leu Ser Ala His Val Pro Gln Val Ser Asn 
            20                  25                  30          


Val Ser Ala Thr Gly Glu Leu Leu Glu Arg Thr Ile Arg Ser Ala Val 
        35                  40                  45              


Glu Gln His Leu Phe Asp Val Asn Asn Ser Gly Gly Gln Ser Ser Glu 
    50                  55                  60                  


Asp Ser Glu Ser Gly Thr Leu Ser Ala Ser Ser Ala Thr Ser Ala Arg 
65                  70                  75                  80  


Gln Arg Arg Arg Gln Ser Lys Glu Gln Asp Glu Val Arg His Gly Arg 
                85                  90                  95      


Asp Lys Gly Leu Ile Asn Lys Glu Asn Thr Pro Ser Gly Phe Asn His 
            100                 105                 110         


Leu Asp Asp Cys Ile Leu Asn Thr Gln Glu Val Glu Lys Val His Lys 
        115                 120                 125             


Asn Thr Phe Gly Cys Ala Gly Glu Arg Ser Lys Pro Lys Arg Gln Lys 
    130                 135                 140                 


Ser Ser Thr Lys Leu Ser Glu Leu His Asp Asn Gln Asp Gly Leu Val 
145                 150                 155                 160 


Asn Met Glu Ser Leu Asn Ser Thr Arg Ser His Glu Arg Thr Gly Pro 
                165                 170                 175     


Asp Asp Phe Glu Trp Met Ser Asp Glu Arg Lys Gly Asn Glu Lys Asp 
            180                 185                 190         


Gly Gly His Thr Gln His Phe Glu Ser Pro Thr Met Lys Ile Gln Glu 
        195                 200                 205             


His Pro Ser Leu Ser Asp Thr Lys Gln Gln Arg Asn Gln Asp Ala Gly 
    210                 215                 220                 


Asp Gln Glu Glu Ser Phe Val Ser Glu Val Pro Gln Ser Asp Leu Thr 
225                 230                 235                 240 


Ala Leu Cys Asp Glu Lys Asn Trp Glu Glu Pro Ile Pro Ala Phe Ser 
                245                 250                 255     


Ser Trp Gln Arg Glu Asn Ser Asp Ser Asp Glu Ala His Leu Ser Pro 
            260                 265                 270         


Gln Ala Gly Arg Leu Ile Arg Gln Leu Leu Asp Glu Asp Ser Asp Pro 
        275                 280                 285             


Met Leu Ser Pro Arg Phe Tyr Ala Tyr Gly Gln Ser Arg Gln Tyr Leu 
    290                 295                 300                 


Asp Asp Thr Glu Val Pro Pro Ser Pro Pro Asn Ser His Ser Phe Met 
305                 310                 315                 320 


Arg Arg Arg Ser Ser Ser Leu Gly Ser Tyr Asp Asp Glu Gln Glu Asp 
                325                 330                 335     


Leu Thr Pro Ala Gln Leu Thr Arg Arg Ile Gln Ser Leu Lys Lys Lys 
            340                 345                 350         


Ile Arg Lys Phe Glu Asp Arg Phe Glu Glu Glu Lys Lys Tyr Arg Pro 
        355                 360                 365             


Ser His Ser Asp Lys Ala Ala Asn Pro Glu Val Leu Lys Trp Thr Asn 
    370                 375                 380                 


Asp Leu Ala Lys Phe Arg Arg Gln Leu Lys Glu Ser Lys Leu Lys Ile 
385                 390                 395                 400 


Ser Glu Glu Asp Leu Thr Pro Arg Met Arg Gln Arg Ser Asn Thr Leu 
                405                 410                 415     


Pro Lys Ser Phe Gly Ser Gln Leu Glu Lys Glu Asp Glu Lys Lys Gln 
            420                 425                 430         


Glu Leu Val Asp Lys Ala Ile Lys Pro Ser Val Glu Ala Thr Leu Glu 
        435                 440                 445             


Ser Ile Gln Arg Lys Leu Gln Glu Lys Arg Ala Glu Ser Ser Arg Pro 
    450                 455                 460                 


Glu Asp Ile Lys Asp Met Thr Lys Asp Gln Ile Ala Asn Glu Lys Val 
465                 470                 475                 480 


Ala Leu Gln Lys Ala Leu Leu Tyr Tyr Glu Ser Ile His Gly Arg Pro 
                485                 490                 495     


Val Thr Lys Asn Glu Arg Gln Val Met Lys Pro Leu Tyr Asp Arg Tyr 
            500                 505                 510         


Arg Leu Val Lys Gln Ile Leu Ser Arg Ala Asn Thr Ile Pro Ile Ile 
        515                 520                 525             


Gly Ser Pro Ser Ser Lys Arg Arg Ser Pro Leu Leu Gln Pro Ile Ile 
    530                 535                 540                 


Glu Gly Glu Thr Ala Ser Phe Phe Lys Glu Ile Lys Glu Glu Glu Glu 
545                 550                 555                 560 


Gly Ser Glu Asp Asp Ser Asn Val Lys Pro Asp Phe Met Val Thr Leu 
                565                 570                 575     


Lys Thr Asp Phe Ser Ala Arg Cys Phe Leu Asp Gln Phe Glu Asp Asp 
            580                 585                 590         


Ala Asp Gly Phe Ile Ser Pro Met Asp Asp Lys Ile Pro Ser Lys Cys 
        595                 600                 605             


Ser Gln Asp Thr Gly Leu Ser Asn Leu His Ala Ala Ser Ile Pro Glu 
    610                 615                 620                 


Leu Leu Glu His Leu Gln Glu Met Arg Glu Glu Lys Lys Arg Ile Arg 
625                 630                 635                 640 


Lys Lys Leu Arg Asp Phe Glu Asp Asn Phe Phe Arg Gln Asn Gly Arg 
                645                 650                 655     


Asn Val Gln Lys Glu Asp Arg Thr Pro Met Ala Glu Glu Tyr Ser Glu 
            660                 665                 670         


Tyr Lys His Ile Lys Ala Lys Leu Arg Leu Leu Glu Val Leu Ile Ser 
        675                 680                 685             


Lys Arg Asp Thr Asp Ser Lys Ser Met 
    690                 695         


<210>  1320
<211>  112
<212>  PRT
<213>  Human

<400>  1320

Met Glu Ala Tyr Glu Gln Val Gln Lys Gly Pro Leu Lys Leu Lys Gly 
1               5                   10                  15      


Val Ala Glu Leu Gly Val Thr Lys Arg Lys Lys Lys Lys Lys Asp Lys 
            20                  25                  30          


Asp Lys Ala Lys Leu Leu Glu Ala Met Gly Thr Ser Lys Lys Asn Glu 
        35                  40                  45              


Glu Glu Lys Arg Arg Gly Leu Asp Lys Arg Thr Pro Ala Gln Ala Ala 
    50                  55                  60                  


Phe Glu Lys Met Gln Glu Lys Arg Gln Met Glu Arg Ile Leu Lys Lys 
65                  70                  75                  80  


Ala Ser Lys Thr His Lys Gln Arg Val Glu Asp Phe Asn Arg His Leu 
                85                  90                  95      


Asp Thr Leu Thr Glu His Tyr Asp Ile Pro Lys Val Ser Trp Thr Lys 
            100                 105                 110         


<210>  1321
<211>  875
<212>  PRT
<213>  Human

<400>  1321

Met Asp Pro Ala Pro Ser Leu Gly Cys Ser Leu Lys Asp Val Lys Trp 
1               5                   10                  15      


Ser Ser Val Ala Val Pro Leu Asp Leu Leu Val Ser Thr Tyr Arg Leu 
            20                  25                  30          


Pro Gln Ile Ala Arg Leu Asp Asn Gly Glu Cys Val Glu Gly Leu Arg 
        35                  40                  45              


Glu Asn Asp Tyr Leu Leu Ile His Ser Cys Arg Gln Trp Thr Thr Ile 
    50                  55                  60                  


Thr Ala His Ser Leu Glu Glu Gly His Tyr Val Ile Gly Pro Lys Ile 
65                  70                  75                  80  


Glu Ile Pro Val His Tyr Ala Gly Gln Phe Lys Leu Leu Glu Gln Asp 
                85                  90                  95      


Arg Asp Ile Lys Glu Pro Val Gln Tyr Phe Asn Ser Val Glu Glu Val 
            100                 105                 110         


Ala Lys Ala Phe Pro Glu Arg Val Tyr Val Met Glu Asp Ile Thr Phe 
        115                 120                 125             


Asn Val Lys Val Ala Ser Gly Glu Cys Asn Glu Asp Thr Glu Val Tyr 
    130                 135                 140                 


Asn Ile Thr Leu Cys Thr Gly Asp Glu Leu Thr Leu Met Gly Gln Ala 
145                 150                 155                 160 


Glu Ile Leu Tyr Ala Lys Thr Phe Lys Glu Lys Ser Arg Leu Asn Thr 
                165                 170                 175     


Ile Phe Lys Lys Ile Gly Lys Leu Asn Ser Ile Ser Lys Leu Gly Lys 
            180                 185                 190         


Gly Lys Met Pro Cys Leu Ile Cys Met Asn His Arg Thr Asn Glu Ser 
        195                 200                 205             


Ile Ser Leu Pro Phe Gln Cys Lys Gly Arg Phe Ser Thr Arg Ser Pro 
    210                 215                 220                 


Leu Glu Leu Gln Met Gln Glu Gly Glu His Thr Ile Arg Asn Ile Val 
225                 230                 235                 240 


Glu Lys Thr Arg Leu Pro Val Asn Val Thr Val Pro Ser Pro Pro Pro 
                245                 250                 255     


Arg Asn Pro Tyr Asp Leu His Phe Ile Arg Glu Gly His Arg Tyr Lys 
            260                 265                 270         


Phe Val Asn Ile Gln Thr Lys Thr Val Val Val Cys Cys Val Leu Arg 
        275                 280                 285             


Asn Asn Lys Ile Leu Pro Met His Phe Pro Leu His Leu Thr Val Pro 
    290                 295                 300                 


Lys Phe Ser Leu Pro Glu His Leu Val Lys Gly Glu Ser Trp Pro Glu 
305                 310                 315                 320 


Thr Leu Val His His Trp Leu Gly Ile Cys Gln Glu Gln Phe Asp Ile 
                325                 330                 335     


Asp Glu Tyr Ser Arg Ala Val Arg Asp Val Lys Thr Asp Trp Asn Glu 
            340                 345                 350         


Glu Cys Lys Ser Pro Lys Lys Gly Arg Cys Ser Gly His Asn His Val 
        355                 360                 365             


Pro Asn Ser Leu Ser Tyr Ala Arg Asp Glu Leu Thr Gln Ser Phe His 
    370                 375                 380                 


Arg Leu Ser Val Cys Val Tyr Gly Asn Asn Leu His Gly Asn Ser Glu 
385                 390                 395                 400 


Val Asn Leu His Gly Cys Arg Asp Leu Gly Gly Asp Trp Ala Pro Phe 
                405                 410                 415     


Pro His Asp Ile Leu Pro Tyr Gln Asp Ser Gly Asp Ser Gly Ser Asp 
            420                 425                 430         


Tyr Leu Phe Pro Glu Ala Ser Glu Glu Ser Ala Gly Ile Pro Gly Lys 
        435                 440                 445             


Ser Glu Leu Pro Tyr Glu Glu Leu Trp Leu Glu Glu Gly Lys Pro Ser 
    450                 455                 460                 


His Gln Pro Leu Thr Arg Ser Leu Ser Glu Lys Asn Arg Cys Asp Gln 
465                 470                 475                 480 


Phe Arg Gly Ser Val Arg Ser Lys Cys Ala Thr Ser Pro Leu Pro Ile 
                485                 490                 495     


Pro Gly Thr Leu Gly Ala Ala Val Lys Ser Ser Asp Thr Ala Leu Pro 
            500                 505                 510         


Pro Pro Pro Val Pro Pro Lys Ser Glu Ala Val Arg Glu Glu Cys Arg 
        515                 520                 525             


Leu Leu Asn Ala Pro Pro Val Pro Pro Arg Ser Ala Lys Pro Leu Ser 
    530                 535                 540                 


Thr Ser Pro Ser Ile Pro Pro Arg Thr Val Lys Pro Ala Arg Gln Gln 
545                 550                 555                 560 


Thr Arg Ser Pro Ser Pro Thr Leu Ser Tyr Tyr Ser Ser Gly Leu His 
                565                 570                 575     


Asn Ile Val Thr Lys Thr Asp Thr Asn Pro Ser Glu Ser Thr Pro Val 
            580                 585                 590         


Ser Cys Tyr Pro Cys Asn Arg Val Lys Thr Asp Ser Val Asp Leu Lys 
        595                 600                 605             


Ser Pro Phe Gly Ser Pro Ser Ala Glu Ala Val Ser Ser Arg Leu Ser 
    610                 615                 620                 


Trp Pro Asn His Tyr Ser Gly Ala Ser Glu Ser Gln Thr Arg Ser Asp 
625                 630                 635                 640 


Phe Leu Leu Asp Pro Ser Arg Ser Tyr Ser Tyr Pro Arg Gln Lys Thr 
                645                 650                 655     


Pro Gly Thr Pro Lys Arg Asn Cys Pro Ala Pro Phe Asp Phe Asp Gly 
            660                 665                 670         


Cys Glu Leu Leu Ala Ser Pro Thr Ser Pro Val Thr Ala Glu Phe Ser 
        675                 680                 685             


Ser Ser Val Ser Gly Cys Pro Lys Ser Ala Ser Tyr Ser Leu Glu Ser 
    690                 695                 700                 


Thr Asp Val Lys Ser Leu Ala Ala Gly Val Thr Lys Gln Ser Thr Ser 
705                 710                 715                 720 


Cys Pro Ala Leu Pro Pro Arg Ala Pro Lys Leu Val Glu Glu Lys Val 
                725                 730                 735     


Ala Ser Glu Thr Ser Pro Leu Pro Leu Lys Ile Asp Gly Ala Glu Glu 
            740                 745                 750         


Asp Pro Lys Ser Gly Ser Pro Asp Leu Ser Glu Asp Gln Tyr Phe Val 
        755                 760                 765             


Lys Lys Gly Met Gln Asp Ile Phe Ser Ala Ser Tyr Pro Phe Ser Ser 
    770                 775                 780                 


Pro Leu His Leu Gln Leu Ala Pro Arg Ser Cys Gly Asp Gly Ser Pro 
785                 790                 795                 800 


Trp Gln Pro Pro Ala Asp Leu Ser Gly Leu Ser Ile Glu Glu Val Ser 
                805                 810                 815     


Lys Ser Leu Arg Phe Ile Gly Leu Ser Glu Asp Val Ile Ser Phe Phe 
            820                 825                 830         


Val Thr Glu Lys Ile Asp Gly Asn Leu Leu Val Gln Leu Thr Glu Glu 
        835                 840                 845             


Ile Leu Ser Glu Asp Phe Lys Leu Ser Lys Leu Gln Val Lys Lys Ile 
    850                 855                 860                 


Met Gln Phe Ile Asn Gly Trp Arg Pro Lys Ile 
865                 870                 875 


<210>  1322
<211>  269
<212>  PRT
<213>  Human

<400>  1322

Asp Ala Trp Ala Val Lys Glu Glu Cys Arg Leu Leu Asn Ala Pro Pro 
1               5                   10                  15      


Val Pro Pro Arg Gly Gly Asn Gly Ser Gly Arg Leu Ser Ser Ser Pro 
            20                  25                  30          


Pro Val Pro Pro Arg Phe Pro Lys Leu Gln Pro Val His Ser Pro Ser 
        35                  40                  45              


Ser Ser Leu Ser Tyr Tyr Ser Ser Gly Leu Gln Asp Gly Ala Gly Ser 
    50                  55                  60                  


Arg Ser Gly Ser Gly Ser Pro Ser Pro Asp Thr Tyr Ser Leu Tyr Cys 
65                  70                  75                  80  


Tyr Pro Cys Thr Trp Gly Asp Cys Lys Glu Pro Val Leu Glu Pro Phe 
                85                  90                  95      


Asp Pro Phe Glu Leu Gly Gln Gly Ser Ser Pro Glu Pro Glu Leu Leu 
            100                 105                 110         


Arg Ser Gln Glu Pro Arg Ala Val Gly Thr Pro Gly Pro Gly Pro Arg 
        115                 120                 125             


Leu Ser Pro Leu Gly Pro Ser Lys Ala Phe Glu Pro Glu Gly Leu Val 
    130                 135                 140                 


Leu His Gln Val Pro Thr Pro Leu Ser Pro Ala Ala Leu Gln Gly Pro 
145                 150                 155                 160 


Glu Ala Gly Gly Ala Leu Phe Leu Thr Gln Gly Arg Leu Glu Gly Pro 
                165                 170                 175     


Pro Ala Ser Pro Arg Asp Gly Ala Thr Gly Phe Gly Val Arg Asp Ala 
            180                 185                 190         


Ser Ser Trp Gln Pro Pro Ala Asp Leu Ser Ala Leu Ser Leu Glu Glu 
        195                 200                 205             


Val Ser Arg Ser Leu Arg Phe Ile Gly Leu Ser Glu Asp Val Val Ser 
    210                 215                 220                 


Phe Phe Ala Arg Glu Arg Ile Asp Gly Ser Ile Phe Val Gln Leu Ser 
225                 230                 235                 240 


Glu Asp Ile Leu Ala Asp Asp Phe His Leu Thr Lys Leu Gln Val Lys 
                245                 250                 255     


Lys Ile Met Gln Phe Ile Lys Gly Trp Arg Pro Lys Ile 
            260                 265                 


<210>  1323
<211>  663
<212>  PRT
<213>  Human

<400>  1323

Met Ala Gly Met Lys Thr Ala Ser Gly Asp Tyr Ile Asp Ser Ser Trp 
1               5                   10                  15      


Glu Leu Arg Val Phe Val Gly Glu Glu Asp Pro Glu Ala Glu Ser Val 
            20                  25                  30          


Thr Leu Arg Val Thr Gly Glu Ser His Ile Gly Gly Val Leu Leu Lys 
        35                  40                  45              


Ile Val Glu Gln Ile Asn Arg Lys Gln Asp Trp Ser Asp His Ala Ile 
    50                  55                  60                  


Trp Trp Glu Gln Lys Arg Gln Trp Leu Leu Gln Thr His Trp Thr Leu 
65                  70                  75                  80  


Asp Lys Tyr Gly Ile Leu Ala Asp Ala Arg Leu Phe Phe Gly Pro Gln 
                85                  90                  95      


His Arg Pro Val Ile Leu Arg Leu Pro Asn Arg Arg Ala Leu Arg Leu 
            100                 105                 110         


Arg Ala Ser Phe Ser Gln Pro Leu Phe Gln Ala Val Ala Ala Ile Cys 
        115                 120                 125             


Arg Leu Leu Ser Ile Arg His Pro Glu Glu Leu Ser Leu Leu Arg Ala 
    130                 135                 140                 


Pro Glu Lys Lys Glu Lys Lys Lys Lys Glu Lys Glu Pro Glu Glu Glu 
145                 150                 155                 160 


Leu Tyr Asp Leu Ser Lys Val Val Leu Ala Gly Gly Val Ala Pro Ala 
                165                 170                 175     


Leu Phe Arg Gly Met Pro Ala His Phe Ser Asp Ser Ala Gln Thr Glu 
            180                 185                 190         


Ala Cys Tyr His Met Leu Ser Arg Pro Gln Pro Pro Pro Asp Pro Leu 
        195                 200                 205             


Leu Leu Gln Arg Leu Pro Arg Pro Ser Ser Leu Ser Asp Lys Thr Gln 
    210                 215                 220                 


Leu His Ser Arg Trp Leu Asp Ser Ser Arg Cys Leu Met Gln Gln Gly 
225                 230                 235                 240 


Ile Lys Ala Gly Asp Ala Leu Trp Leu Arg Phe Lys Tyr Tyr Ser Phe 
                245                 250                 255     


Phe Asp Leu Asp Pro Lys Thr Asp Pro Val Arg Leu Thr Gln Leu Tyr 
            260                 265                 270         


Glu Gln Ala Arg Trp Asp Leu Leu Leu Glu Glu Ile Asp Cys Thr Glu 
        275                 280                 285             


Glu Glu Met Met Val Phe Ala Ala Leu Gln Tyr His Ile Asn Lys Leu 
    290                 295                 300                 


Ser Gln Ser Gly Glu Val Gly Glu Pro Ala Gly Thr Asp Pro Gly Leu 
305                 310                 315                 320 


Asp Asp Leu Asp Val Ala Leu Ser Asn Leu Glu Val Lys Leu Glu Gly 
                325                 330                 335     


Ser Ala Pro Thr Asp Val Leu Asp Ser Leu Thr Thr Ile Pro Glu Leu 
            340                 345                 350         


Lys Asp His Leu Arg Ile Phe Arg Pro Arg Lys Leu Thr Leu Lys Gly 
        355                 360                 365             


Tyr Arg Gln His Trp Val Val Phe Lys Glu Thr Thr Leu Ser Tyr Tyr 
    370                 375                 380                 


Lys Ser Gln Asp Glu Ala Pro Gly Asp Pro Ile Gln Gln Leu Asn Leu 
385                 390                 395                 400 


Lys Gly Cys Glu Val Val Pro Asp Val Asn Val Ser Gly Gln Lys Phe 
                405                 410                 415     


Cys Ile Lys Leu Leu Val Pro Ser Pro Glu Gly Met Ser Glu Ile Tyr 
            420                 425                 430         


Leu Arg Cys Gln Asp Glu Gln Gln Tyr Ala Arg Trp Met Ala Gly Cys 
        435                 440                 445             


Arg Leu Ala Ser Lys Gly Arg Thr Met Ala Asp Ser Ser Tyr Thr Ser 
    450                 455                 460                 


Glu Val Gln Ala Ile Leu Ala Phe Leu Ser Leu Gln Arg Thr Gly Ser 
465                 470                 475                 480 


Gly Gly Pro Gly Asn His Pro His Gly Pro Asp Ala Ser Ala Glu Gly 
                485                 490                 495     


Leu Asn Pro Tyr Gly Leu Val Ala Pro Arg Phe Gln Arg Lys Phe Lys 
            500                 505                 510         


Ala Lys Gln Leu Thr Pro Arg Ile Leu Glu Ala His Gln Asn Val Ala 
        515                 520                 525             


Gln Leu Ser Leu Ala Glu Ala Gln Leu Arg Phe Ile Gln Ala Trp Gln 
    530                 535                 540                 


Ser Leu Pro Asp Phe Gly Ile Ser Tyr Val Met Val Arg Phe Lys Gly 
545                 550                 555                 560 


Ser Arg Lys Asp Glu Ile Leu Gly Ile Ala Asn Asn Arg Leu Ile Arg 
                565                 570                 575     


Ile Asp Leu Ala Val Gly Asp Val Val Lys Thr Trp Arg Phe Ser Asn 
            580                 585                 590         


Met Arg Gln Trp Asn Val Asn Trp Asp Ile Arg Gln Val Ala Ile Glu 
        595                 600                 605             


Phe Asp Glu His Ile Asn Val Ala Phe Ser Cys Val Ser Ala Ser Cys 
    610                 615                 620                 


Arg Ile Val His Glu Tyr Ile Gly Gly Tyr Ile Phe Leu Ser Thr Arg 
625                 630                 635                 640 


Glu Arg Ala Arg Gly Glu Glu Leu Asp Glu Asp Leu Phe Leu Gln Leu 
                645                 650                 655     


Thr Gly Gly His Glu Ala Phe 
            660             


<210>  1324
<211>  1219
<212>  PRT
<213>  Human

<400>  1324

Met Phe Gly Ala Gly Asp Glu Asp Asp Thr Asp Phe Leu Ser Pro Ser 
1               5                   10                  15      


Gly Gly Ala Arg Leu Ala Ser Leu Phe Gly Leu Asp Gln Ala Ala Ala 
            20                  25                  30          


Gly His Gly Asn Glu Phe Phe Gln Tyr Thr Ala Pro Lys Gln Pro Lys 
        35                  40                  45              


Lys Gly Gln Gly Thr Ala Ala Thr Gly Asn Gln Ala Thr Pro Lys Thr 
    50                  55                  60                  


Ala Pro Ala Thr Met Ser Thr Pro Thr Ile Leu Val Ala Thr Ala Val 
65                  70                  75                  80  


His Ala Tyr Arg Tyr Thr Asn Gly Gln Tyr Val Lys Gln Gly Lys Phe 
                85                  90                  95      


Gly Ala Ala Val Leu Gly Asn His Thr Ala Arg Glu Tyr Arg Ile Leu 
            100                 105                 110         


Leu Tyr Ile Ser Gln Gln Gln Pro Val Thr Val Ala Arg Ile His Val 
        115                 120                 125             


Asn Phe Glu Leu Met Val Arg Pro Asn Asn Tyr Ser Thr Phe Tyr Asp 
    130                 135                 140                 


Asp Gln Arg Gln Asn Trp Ser Ile Met Phe Glu Ser Glu Lys Ala Ala 
145                 150                 155                 160 


Val Glu Phe Asn Lys Gln Val Cys Ile Ala Lys Cys Asn Ser Thr Ser 
                165                 170                 175     


Ser Leu Asp Ala Val Leu Ser Gln Asp Leu Ile Val Ala Asp Gly Pro 
            180                 185                 190         


Ala Val Glu Val Gly Asp Ser Leu Glu Val Ala Tyr Thr Gly Trp Leu 
        195                 200                 205             


Phe Gln Asn His Val Leu Gly Gln Val Phe Asp Ser Thr Ala Asn Lys 
    210                 215                 220                 


Asp Lys Leu Leu Arg Leu Lys Leu Gly Ser Gly Lys Val Ile Lys Gly 
225                 230                 235                 240 


Trp Glu Asp Gly Met Leu Gly Met Lys Lys Gly Gly Lys Arg Leu Leu 
                245                 250                 255     


Ile Val Pro Pro Ala Cys Ala Val Gly Ser Glu Gly Val Ile Gly Trp 
            260                 265                 270         


Thr Gln Ala Thr Asp Ser Ile Leu Val Phe Glu Val Glu Val Arg Arg 
        275                 280                 285             


Val Lys Phe Ala Arg Asp Ser Gly Ser Asp Gly His Ser Val Ser Ser 
    290                 295                 300                 


Arg Asp Ser Ala Ala Pro Ser Pro Ile Pro Gly Ala Asp Asn Leu Ser 
305                 310                 315                 320 


Ala Asp Pro Val Val Ser Pro Pro Thr Ser Ile Pro Phe Lys Ser Gly 
                325                 330                 335     


Glu Pro Ala Leu Arg Thr Lys Ser Asn Ser Leu Ser Glu Gln Leu Ala 
            340                 345                 350         


Ile Asn Thr Ser Pro Asp Ala Val Lys Ala Lys Leu Ile Ser Arg Met 
        355                 360                 365             


Ala Lys Met Gly Gln Pro Met Leu Pro Ile Leu Pro Pro Gln Leu Asp 
    370                 375                 380                 


Ser Asn Asp Ser Glu Ile Glu Asp Val Asn Thr Leu Gln Gly Gly Gly 
385                 390                 395                 400 


Gln Pro Val Val Thr Pro Ser Val Gln Pro Ser Leu His Pro Ala His 
                405                 410                 415     


Pro Ala Leu Pro Gln Met Thr Ser Gln Ala Pro Gln Pro Ser Val Thr 
            420                 425                 430         


Gly Leu Gln Ala Pro Ser Ala Ala Leu Met Gln Val Ser Ser Leu Asp 
        435                 440                 445             


Ser His Ser Ala Val Ser Gly Asn Ala Gln Ser Phe Gln Pro Tyr Ala 
    450                 455                 460                 


Gly Met Gln Ala Tyr Ala Tyr Pro Gln Ala Ser Ala Val Thr Ser Gln 
465                 470                 475                 480 


Leu Gln Pro Val Arg Pro Leu Tyr Pro Ala Pro Leu Ser Gln Pro Pro 
                485                 490                 495     


His Phe Gln Gly Ser Gly Asp Met Ala Ser Phe Leu Met Thr Glu Ala 
            500                 505                 510         


Arg Gln His Asn Thr Glu Ile Arg Met Ala Val Ser Lys Val Ala Asp 
        515                 520                 525             


Lys Met Asp His Leu Met Thr Lys Val Glu Glu Leu Gln Lys His Ser 
    530                 535                 540                 


Ala Gly Asn Ser Met Leu Ile Pro Ser Met Ser Val Thr Met Glu Thr 
545                 550                 555                 560 


Ser Met Ile Met Ser Asn Ile Gln Arg Ile Ile Gln Glu Asn Glu Arg 
                565                 570                 575     


Leu Lys Gln Glu Ile Leu Glu Lys Ser Asn Arg Ile Glu Glu Gln Asn 
            580                 585                 590         


Asp Lys Ile Ser Glu Leu Ile Glu Arg Asn Gln Arg Tyr Val Glu Gln 
        595                 600                 605             


Ser Asn Leu Met Met Glu Lys Arg Asn Asn Ser Leu Gln Thr Ala Thr 
    610                 615                 620                 


Glu Asn Thr Gln Ala Arg Val Leu His Ala Glu Gln Glu Lys Ala Lys 
625                 630                 635                 640 


Val Thr Glu Glu Leu Ala Ala Ala Thr Ala Gln Val Ser His Leu Gln 
                645                 650                 655     


Leu Lys Met Thr Ala His Gln Lys Lys Glu Thr Glu Leu Gln Met Gln 
            660                 665                 670         


Leu Thr Glu Ser Leu Lys Glu Thr Asp Leu Leu Arg Gly Gln Leu Thr 
        675                 680                 685             


Lys Val Gln Ala Lys Leu Ser Glu Leu Gln Glu Thr Ser Glu Gln Ala 
    690                 695                 700                 


Gln Ser Lys Phe Lys Ser Glu Lys Gln Asn Arg Lys Gln Leu Glu Leu 
705                 710                 715                 720 


Lys Val Thr Ser Leu Glu Glu Glu Leu Thr Asp Leu Arg Val Glu Lys 
                725                 730                 735     


Glu Ser Leu Glu Lys Asn Leu Ser Glu Arg Lys Lys Lys Ser Ala Gln 
            740                 745                 750         


Glu Arg Ser Gln Ala Glu Glu Glu Ile Asp Glu Ile Arg Lys Ser Tyr 
        755                 760                 765             


Gln Glu Glu Leu Asp Lys Leu Arg Gln Leu Leu Lys Lys Thr Arg Val 
    770                 775                 780                 


Ser Thr Asp Gln Ala Ala Ala Glu Gln Leu Ser Leu Val Gln Ala Glu 
785                 790                 795                 800 


Leu Gln Thr Gln Trp Glu Ala Lys Cys Glu His Leu Leu Ala Ser Ala 
                805                 810                 815     


Lys Asp Glu His Leu Gln Gln Tyr Gln Glu Val Cys Ala Gln Arg Asp 
            820                 825                 830         


Ala Tyr Gln Gln Lys Leu Val Gln Leu Gln Glu Lys Cys Leu Ala Leu 
        835                 840                 845             


Gln Ala Gln Ile Thr Ala Leu Thr Lys Gln Asn Glu Gln His Ile Lys 
    850                 855                 860                 


Glu Leu Glu Lys Asn Lys Ser Gln Met Ser Gly Val Glu Ala Ala Ala 
865                 870                 875                 880 


Ser Asp Pro Ser Glu Lys Val Lys Lys Ile Met Asn Gln Val Phe Gln 
                885                 890                 895     


Ser Leu Arg Arg Glu Phe Glu Leu Glu Glu Ser Tyr Asn Gly Arg Thr 
            900                 905                 910         


Ile Leu Gly Thr Ile Met Asn Thr Ile Lys Met Val Thr Leu Gln Leu 
        915                 920                 925             


Leu Asn Gln Gln Glu Gln Glu Lys Glu Glu Ser Ser Ser Glu Glu Glu 
    930                 935                 940                 


Glu Glu Lys Ala Glu Glu Arg Pro Arg Arg Pro Ser Gln Glu Gln Ser 
945                 950                 955                 960 


Ala Ser Ala Ser Ser Gly Gln Pro Gln Ala Pro Leu Asn Arg Glu Arg 
                965                 970                 975     


Pro Glu Ser Pro Met Val Pro Ser Glu Gln Val Val Glu Glu Ala Val 
            980                 985                 990         


Pro Leu Pro Pro Gln Ala Leu Thr  Thr Ser Gln Asp Gly  His Arg Arg 
        995                 1000                 1005             


Lys Gly  Asp Ser Glu Ala Glu  Ala Leu Ser Glu Ile  Lys Asp Gly 
    1010                 1015                 1020             


Ser Leu  Pro Pro Glu Leu Ser  Cys Ile Pro Ser His  Arg Val Leu 
    1025                 1030                 1035             


Gly Pro  Pro Thr Ser Ile Pro  Pro Glu Pro Leu Gly  Pro Val Ser 
    1040                 1045                 1050             


Met Asp  Ser Glu Cys Glu Glu  Ser Leu Ala Ala Ser  Pro Met Ala 
    1055                 1060                 1065             


Ala Lys  Pro Asp Asn Pro Ser  Gly Lys Val Cys Val  Arg Glu Val 
    1070                 1075                 1080             


Ala Pro  Asp Gly Pro Leu Gln  Glu Ser Ser Thr Arg  Leu Ser Leu 
    1085                 1090                 1095             


Thr Ser  Asp Pro Glu Glu Gly  Asp Pro Leu Ala Leu  Gly Pro Glu 
    1100                 1105                 1110             


Ser Pro  Gly Glu Pro Gln Pro  Pro Gln Leu Lys Lys  Asp Asp Val 
    1115                 1120                 1125             


Thr Ser  Ser Thr Gly Pro His  Lys Glu Leu Ser Ser  Thr Glu Ala 
    1130                 1135                 1140             


Gly Ser  Thr Val Ala Gly Ala  Ala Leu Arg Pro Ser  His His Ser 
    1145                 1150                 1155             


Gln Arg  Ser Ser Leu Ser Gly  Asp Glu Glu Asp Glu  Leu Phe Lys 
    1160                 1165                 1170             


Gly Ala  Thr Leu Lys Ala Leu  Arg Pro Lys Ala Gln  Pro Glu Glu 
    1175                 1180                 1185             


Glu Asp  Glu Asp Glu Val Ser  Met Lys Gly Arg Pro  Pro Pro Thr 
    1190                 1195                 1200             


Pro Leu  Phe Gly Asp Asp Asp  Asp Asp Asp Asp Ile  Asp Trp Leu 
    1205                 1210                 1215             


Gly 
    


<210>  1325
<211>  432
<212>  PRT
<213>  Human

<400>  1325

Met Glu Arg Arg Arg Ile Thr Ser Ala Ala Arg Arg Ser Tyr Val Ser 
1               5                   10                  15      


Ser Gly Glu Met Met Val Gly Gly Leu Ala Pro Gly Arg Arg Leu Gly 
            20                  25                  30          


Pro Gly Thr Arg Leu Ser Leu Ala Arg Met Pro Pro Pro Leu Pro Thr 
        35                  40                  45              


Arg Val Asp Phe Ser Leu Ala Gly Ala Leu Asn Ala Gly Phe Lys Glu 
    50                  55                  60                  


Thr Arg Ala Ser Glu Arg Ala Glu Met Met Glu Leu Asn Asp Arg Phe 
65                  70                  75                  80  


Ala Ser Tyr Ile Glu Lys Val Arg Phe Leu Glu Gln Gln Asn Lys Ala 
                85                  90                  95      


Leu Ala Ala Glu Leu Asn Gln Leu Arg Ala Lys Glu Pro Thr Lys Leu 
            100                 105                 110         


Ala Asp Val Tyr Gln Ala Glu Leu Arg Glu Leu Arg Leu Arg Leu Asp 
        115                 120                 125             


Gln Leu Thr Ala Asn Ser Ala Arg Leu Glu Val Glu Arg Asp Asn Leu 
    130                 135                 140                 


Ala Gln Asp Leu Ala Thr Val Arg Gln Lys Leu Gln Asp Glu Thr Asn 
145                 150                 155                 160 


Leu Arg Leu Glu Ala Glu Asn Asn Leu Ala Ala Tyr Arg Gln Glu Ala 
                165                 170                 175     


Asp Glu Ala Thr Leu Ala Arg Leu Asp Leu Glu Arg Lys Ile Glu Ser 
            180                 185                 190         


Leu Glu Glu Glu Ile Arg Phe Leu Arg Lys Ile His Glu Glu Glu Val 
        195                 200                 205             


Arg Glu Leu Gln Glu Gln Leu Ala Arg Gln Gln Val His Val Glu Leu 
    210                 215                 220                 


Asp Val Ala Lys Pro Asp Leu Thr Ala Ala Leu Lys Glu Ile Arg Thr 
225                 230                 235                 240 


Gln Tyr Glu Ala Met Ala Ser Ser Asn Met His Glu Ala Glu Glu Trp 
                245                 250                 255     


Tyr Arg Ser Lys Phe Ala Asp Leu Thr Asp Ala Ala Ala Arg Asn Ala 
            260                 265                 270         


Glu Leu Leu Arg Gln Ala Lys His Glu Ala Asn Asp Tyr Arg Arg Gln 
        275                 280                 285             


Leu Gln Ser Leu Thr Cys Asp Leu Glu Ser Leu Arg Gly Thr Asn Glu 
    290                 295                 300                 


Ser Leu Glu Arg Gln Met Arg Glu Gln Glu Glu Arg His Val Arg Glu 
305                 310                 315                 320 


Ala Ala Ser Tyr Gln Glu Ala Leu Ala Arg Leu Glu Glu Glu Gly Gln 
                325                 330                 335     


Ser Leu Lys Asp Glu Met Ala Arg His Leu Gln Glu Tyr Gln Asp Leu 
            340                 345                 350         


Leu Asn Val Lys Leu Ala Leu Asp Ile Glu Ile Ala Thr Tyr Arg Lys 
        355                 360                 365             


Leu Leu Glu Gly Glu Glu Asn Arg Ile Thr Ile Pro Val Gln Thr Phe 
    370                 375                 380                 


Ser Asn Leu Gln Ile Arg Glu Thr Ser Leu Asp Thr Lys Ser Val Ser 
385                 390                 395                 400 


Glu Gly His Leu Lys Arg Asn Ile Val Val Lys Thr Val Glu Met Arg 
                405                 410                 415     


Asp Gly Glu Val Ile Lys Glu Ser Lys Gln Glu His Lys Asp Val Met 
            420                 425                 430         


<210>  1326
<211>  298
<212>  PRT
<213>  Human

<400>  1326

Met Ala Ala Arg Arg Ala Leu His Phe Val Phe Lys Val Gly Asn Arg 
1               5                   10                  15      


Phe Gln Thr Ala Arg Phe Tyr Arg Asp Val Leu Gly Met Lys Val Leu 
            20                  25                  30          


Arg His Glu Glu Phe Glu Glu Gly Cys Lys Ala Ala Cys Asn Gly Pro 
        35                  40                  45              


Tyr Asp Gly Lys Trp Ser Lys Thr Met Val Gly Phe Gly Pro Glu Asp 
    50                  55                  60                  


Asp His Phe Val Ala Glu Leu Thr Tyr Asn Tyr Gly Val Gly Asp Tyr 
65                  70                  75                  80  


Lys Leu Gly Asn Asp Phe Met Gly Ile Thr Leu Ala Ser Ser Gln Ala 
                85                  90                  95      


Val Ser Asn Ala Arg Lys Leu Glu Trp Pro Leu Thr Glu Val Ala Glu 
            100                 105                 110         


Gly Val Phe Glu Thr Glu Ala Pro Gly Gly Tyr Lys Phe Tyr Leu Gln 
        115                 120                 125             


Asn Arg Ser Leu Pro Gln Ser Asp Pro Val Leu Lys Val Thr Leu Ala 
    130                 135                 140                 


Val Ser Asp Leu Gln Lys Ser Leu Asn Tyr Trp Cys Asn Leu Leu Gly 
145                 150                 155                 160 


Met Lys Ile Tyr Glu Lys Asp Glu Glu Lys Gln Arg Ala Leu Leu Gly 
                165                 170                 175     


Tyr Ala Asp Asn Gln Cys Lys Leu Glu Leu Gln Gly Val Lys Gly Gly 
            180                 185                 190         


Val Asp His Ala Ala Ala Phe Gly Arg Ile Ala Phe Ser Cys Pro Gln 
        195                 200                 205             


Lys Glu Leu Pro Asp Leu Glu Asp Leu Met Lys Arg Glu Asn Gln Lys 
    210                 215                 220                 


Ile Leu Thr Pro Leu Val Ser Leu Asp Thr Pro Gly Lys Ala Thr Val 
225                 230                 235                 240 


Gln Val Val Ile Leu Ala Asp Pro Asp Gly His Glu Ile Cys Phe Val 
                245                 250                 255     


Gly Asp Glu Ala Phe Arg Glu Leu Ser Lys Met Asp Pro Glu Gly Ser 
            260                 265                 270         


Lys Leu Leu Asp Asp Ala Met Ala Ala Asp Lys Ser Asp Glu Trp Phe 
        275                 280                 285             


Ala Lys His Asn Lys Pro Lys Ala Ser Gly 
    290                 295             


<210>  1327
<211>  368
<212>  PRT
<213>  Human

<400>  1327

Met Cys Ser Leu Pro Arg Gly Phe Glu Pro Gln Ala Pro Glu Asp Leu 
1               5                   10                  15      


Ala Gln Arg Ser Leu Val Glu Leu Arg Glu Met Leu Lys Arg Gln Glu 
            20                  25                  30          


Arg Leu Leu Arg Asn Glu Lys Phe Ile Cys Lys Leu Pro Asp Lys Gly 
        35                  40                  45              


Lys Lys Ile Phe Asp Ser Phe Ala Lys Leu Lys Ala Ala Ile Ala Glu 
    50                  55                  60                  


Cys Glu Glu Val Arg Arg Lys Ser Glu Leu Phe Asn Pro Val Ser Leu 
65                  70                  75                  80  


Asp Cys Lys Leu Arg Gln Lys Ala Ile Ala Glu Val Asp Val Gly Thr 
                85                  90                  95      


Asp Lys Ala Gln Asn Ser Asp Pro Ile Leu Asp Thr Ser Ser Leu Val 
            100                 105                 110         


Pro Gly Cys Ser Ser Val Asp Asn Ile Lys Ser Ser Gln Thr Ser Gln 
        115                 120                 125             


Asn Gln Gly Leu Gly Arg Pro Thr Leu Glu Gly Asp Glu Glu Thr Ser 
    130                 135                 140                 


Glu Val Glu Tyr Thr Val Asn Lys Gly Pro Ala Ser Ser Asn Arg Asp 
145                 150                 155                 160 


Arg Val Pro Pro Ser Ser Glu Ala Ser Glu His His Pro Arg His Arg 
                165                 170                 175     


Val Ser Ser Gln Ala Glu Asp Thr Ser Ser Ser Phe Asp Asn Leu Phe 
            180                 185                 190         


Ile Asp Arg Leu Gln Arg Ile Thr Ile Ala Asp Gln Gly Glu Gln Gln 
        195                 200                 205             


Ser Glu Glu Asn Ala Ser Thr Lys Asn Leu Thr Gly Leu Ser Ser Gly 
    210                 215                 220                 


Thr Glu Lys Lys Pro His Tyr Met Glu Val Leu Glu Met Arg Ala Lys 
225                 230                 235                 240 


Asn Pro Val Pro Gln Leu Arg Lys Phe Lys Thr Asn Val Leu Pro Phe 
                245                 250                 255     


Arg Gln Asn Asp Ser Ser Ser His Cys Gln Lys Ser Gly Ser Pro Ile 
            260                 265                 270         


Ser Ser Glu Glu Arg Arg Arg Arg Asp Lys Gln His Leu Asp Asp Ile 
        275                 280                 285             


Thr Ala Ala Arg Leu Leu Pro Leu His His Met Pro Thr Gln Leu Leu 
    290                 295                 300                 


Ser Ile Glu Glu Ser Leu Ala Leu Gln Lys Gln Gln Lys Gln Asn Tyr 
305                 310                 315                 320 


Glu Glu Met Gln Ala Lys Leu Ala Ala Gln Lys Leu Ala Glu Arg Leu 
                325                 330                 335     


Asn Ile Lys Met Arg Ser Tyr Asn Pro Glu Gly Glu Ser Ser Gly Arg 
            340                 345                 350         


Tyr Arg Glu Val Arg Asp Glu Asp Asp Asp Trp Ser Ser Asp Glu Phe 
        355                 360                 365             


<210>  1328
<211>  138
<212>  PRT
<213>  Human

<400>  1328

Met Arg Gly Arg Glu Leu Pro Leu Val Leu Leu Ala Leu Val Leu Cys 
1               5                   10                  15      


Leu Ala Pro Arg Gly Arg Ala Val Pro Leu Pro Ala Gly Gly Gly Thr 
            20                  25                  30          


Val Leu Thr Lys Met Tyr Pro Arg Gly Asn His Trp Ala Val Gly His 
        35                  40                  45              


Leu Met Gly Lys Lys Ser Thr Gly Glu Ser Ser Ser Val Ser Glu Arg 
    50                  55                  60                  


Gly Ser Leu Lys Gln Gln Leu Arg Glu Tyr Ile Arg Trp Glu Glu Ala 
65                  70                  75                  80  


Ala Arg Asn Leu Leu Gly Leu Ile Glu Ala Lys Glu Asn Arg Asn His 
                85                  90                  95      


Gln Pro Pro Gln Pro Lys Ala Leu Gly Asn Gln Gln Pro Ser Trp Asp 
            100                 105                 110         


Ser Glu Asp Ser Ser Asn Phe Lys Asp Leu Val Asp Ser Leu Leu Gln 
        115                 120                 125             


Val Leu Asn Val Lys Glu Gly Thr Pro Ser 
    130                 135             


<210>  1329
<211>  637
<212>  PRT
<213>  Human

<400>  1329

Met Asp Pro Gly Ser Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly 
1               5                   10                  15      


Ser Ser Ser Gly Ser Ser Ser Ser Asp Ser Ala Pro Asp Cys Trp Asp 
            20                  25                  30          


Gln Ala Asp Met Glu Ala Pro Gly Pro Gly Pro Cys Gly Gly Gly Gly 
        35                  40                  45              


Ser Leu Ala Ala Ala Ala Glu Ala Gln Arg Glu Asn Leu Ser Ala Ala 
    50                  55                  60                  


Phe Ser Arg Gln Leu Asn Val Asn Ala Lys Pro Phe Val Pro Asn Val 
65                  70                  75                  80  


His Ala Ala Glu Phe Val Pro Ser Phe Leu Arg Gly Pro Ala Ala Pro 
                85                  90                  95      


Pro Pro Pro Ala Gly Gly Ala Ala Asn Asn His Gly Ala Gly Ser Gly 
            100                 105                 110         


Ala Gly Gly Arg Ala Ala Pro Val Glu Ser Ser Gln Glu Glu Gln Ser 
        115                 120                 125             


Leu Cys Glu Gly Ser Asn Ser Ala Val Ser Met Glu Leu Ser Glu Pro 
    130                 135                 140                 


Ile Val Glu Asn Gly Glu Thr Glu Met Ser Pro Glu Glu Ser Trp Glu 
145                 150                 155                 160 


His Lys Glu Glu Ile Ser Glu Ala Glu Pro Gly Gly Gly Ser Leu Gly 
                165                 170                 175     


Asp Gly Arg Pro Pro Glu Glu Ser Ala His Glu Met Met Glu Glu Glu 
            180                 185                 190         


Glu Glu Ile Pro Lys Pro Lys Ser Val Val Ala Pro Pro Gly Ala Pro 
        195                 200                 205             


Lys Lys Glu His Val Asn Val Val Phe Ile Gly His Val Asp Ala Gly 
    210                 215                 220                 


Lys Ser Thr Ile Gly Gly Gln Ile Met Tyr Leu Thr Gly Met Val Asp 
225                 230                 235                 240 


Lys Arg Thr Leu Glu Lys Tyr Glu Arg Glu Ala Lys Glu Lys Asn Arg 
                245                 250                 255     


Glu Thr Trp Tyr Leu Ser Trp Ala Leu Asp Thr Asn Gln Glu Glu Arg 
            260                 265                 270         


Asp Lys Gly Lys Thr Val Glu Val Gly Arg Ala Tyr Phe Glu Thr Glu 
        275                 280                 285             


Lys Lys His Phe Thr Ile Leu Asp Ala Pro Gly His Lys Ser Phe Val 
    290                 295                 300                 


Pro Asn Met Ile Gly Gly Ala Ser Gln Ala Asp Leu Ala Val Leu Val 
305                 310                 315                 320 


Ile Ser Ala Arg Lys Gly Glu Phe Glu Thr Gly Phe Glu Lys Gly Gly 
                325                 330                 335     


Gln Thr Arg Glu His Ala Met Leu Ala Lys Thr Ala Gly Val Lys His 
            340                 345                 350         


Leu Ile Val Leu Ile Asn Lys Met Asp Asp Pro Thr Val Asn Trp Ser 
        355                 360                 365             


Asn Glu Arg Tyr Glu Glu Cys Lys Glu Lys Leu Val Pro Phe Leu Lys 
    370                 375                 380                 


Lys Val Gly Phe Asn Pro Lys Lys Asp Ile His Phe Met Pro Cys Ser 
385                 390                 395                 400 


Gly Leu Thr Gly Ala Asn Leu Lys Glu Gln Ser Asp Phe Cys Pro Trp 
                405                 410                 415     


Tyr Ile Gly Leu Pro Phe Ile Pro Tyr Leu Asp Asn Leu Pro Asn Phe 
            420                 425                 430         


Asn Arg Ser Val Asp Gly Pro Ile Arg Leu Pro Ile Val Asp Lys Tyr 
        435                 440                 445             


Lys Asp Met Gly Thr Val Val Leu Gly Lys Leu Glu Ser Gly Ser Ile 
    450                 455                 460                 


Cys Lys Gly Gln Gln Leu Val Met Met Pro Asn Lys His Asn Val Glu 
465                 470                 475                 480 


Val Leu Gly Ile Leu Ser Asp Asp Val Glu Thr Asp Thr Val Ala Pro 
                485                 490                 495     


Gly Glu Asn Leu Lys Ile Arg Leu Lys Gly Ile Glu Glu Glu Glu Ile 
            500                 505                 510         


Leu Pro Gly Phe Ile Leu Cys Asp Pro Asn Asn Leu Cys His Ser Gly 
        515                 520                 525             


Arg Thr Phe Asp Ala Gln Ile Val Ile Ile Glu His Lys Ser Ile Ile 
    530                 535                 540                 


Cys Pro Gly Tyr Asn Ala Val Leu His Ile His Thr Cys Ile Glu Glu 
545                 550                 555                 560 


Val Glu Ile Thr Ala Leu Ile Cys Leu Val Asp Lys Lys Ser Gly Glu 
                565                 570                 575     


Lys Ser Lys Thr Arg Pro Arg Phe Val Lys Gln Asp Gln Val Cys Ile 
            580                 585                 590         


Ala Arg Leu Arg Thr Ala Gly Thr Ile Cys Leu Glu Thr Phe Lys Asp 
        595                 600                 605             


Phe Pro Gln Met Gly Arg Phe Thr Leu Arg Asp Glu Gly Lys Thr Ile 
    610                 615                 620                 


Ala Ile Gly Lys Val Leu Lys Leu Val Pro Glu Lys Asp 
625                 630                 635         


<210>  1330
<211>  409
<212>  PRT
<213>  Human

<400>  1330

Met Ala Asp Ser Ser Gly Arg Gly Ala Gly Lys Pro Ala Thr Gly Pro 
1               5                   10                  15      


Thr Asn Ser Ser Ser Ala Lys Lys Lys Asp Lys Arg Val Gln Gly Gly 
            20                  25                  30          


Arg Val Ile Glu Ser Arg Tyr Leu Gln Tyr Glu Lys Lys Thr Thr Gln 
        35                  40                  45              


Lys Ala Pro Ala Gly Asp Gly Ser Gln Thr Arg Gly Lys Met Ser Glu 
    50                  55                  60                  


Gly Gly Arg Lys Ser Ser Leu Leu Gln Lys Ser Lys Asp Ser Ser Gly 
65                  70                  75                  80  


Val Gly Lys Gly Asp Leu Gln Ser Thr Leu Leu Glu Gly His Gly Thr 
                85                  90                  95      


Ala Pro Pro Asp Leu Asp Leu Ser Ala Ile Asn Asp Lys Ser Ile Val 
            100                 105                 110         


Lys Lys Thr Pro Gln Leu Ala Lys Thr Ile Ser Lys Lys Pro Glu Ser 
        115                 120                 125             


Thr Ser Phe Ser Ala Pro Arg Lys Lys Ser Pro Asp Leu Ser Glu Ala 
    130                 135                 140                 


Met Glu Met Met Glu Ser Gln Thr Leu Leu Leu Thr Leu Leu Ser Val 
145                 150                 155                 160 


Lys Met Glu Asn Asn Leu Ala Glu Phe Glu Arg Arg Ala Glu Lys Asn 
                165                 170                 175     


Leu Leu Ile Met Cys Lys Glu Lys Glu Lys Leu Gln Lys Lys Ala His 
            180                 185                 190         


Glu Leu Lys Arg Arg Leu Leu Leu Ser Gln Arg Lys Arg Glu Leu Ala 
        195                 200                 205             


Asp Val Leu Asp Ala Gln Ile Glu Met Leu Ser Pro Phe Glu Ala Val 
    210                 215                 220                 


Ala Thr Arg Phe Lys Glu Gln Tyr Arg Thr Phe Ala Thr Ala Leu Asp 
225                 230                 235                 240 


Thr Thr Arg His Glu Leu Pro Val Arg Ser Ile His Leu Glu Gly Asp 
                245                 250                 255     


Gly Gln Gln Leu Leu Asp Ala Leu Gln His Glu Leu Val Thr Thr Gln 
            260                 265                 270         


Arg Leu Leu Gly Glu Leu Asp Val Gly Asp Ser Glu Glu Asn Val Gln 
        275                 280                 285             


Val Leu Asp Leu Leu Ser Glu Leu Lys Asp Val Thr Ala Lys Lys Asp 
    290                 295                 300                 


Leu Glu Leu Arg Arg Ser Phe Ala Gln Val Leu Glu Leu Ser Ala Glu 
305                 310                 315                 320 


Ala Ser Lys Glu Ala Ala Leu Ala Asn Gln Glu Val Trp Glu Glu Thr 
                325                 330                 335     


Gln Gly Met Ala Pro Pro Ser Arg Trp Tyr Phe Asn Gln Asp Ser Ala 
            340                 345                 350         


Cys Arg Glu Ser Gly Gly Ala Pro Lys Asn Thr Pro Leu Ser Glu Asp 
        355                 360                 365             


Asp Asn Pro Gly Ala Ser Ser Ala Pro Ala Gln Ala Thr Phe Ile Ser 
    370                 375                 380                 


Pro Ser Glu Asp Phe Ser Ser Ser Ser Gln Ala Glu Val Pro Pro Ser 
385                 390                 395                 400 


Leu Ser Arg Ser Gly Arg Asp Leu Ser 
                405                 


<210>  1331
<211>  2035
<212>  PRT
<213>  Human

<400>  1331

Met Ala Ser Ala Val Ser Pro Ala Asn Leu Pro Ala Val Leu Leu Gln 
1               5                   10                  15      


Pro Arg Trp Lys Arg Val Val Gly Trp Ser Gly Pro Val Pro Arg Pro 
            20                  25                  30          


Arg His Gly His Arg Ala Val Ala Ile Lys Glu Leu Ile Val Val Phe 
        35                  40                  45              


Gly Gly Gly Asn Glu Gly Ile Val Asp Glu Leu His Val Tyr Asn Thr 
    50                  55                  60                  


Ala Thr Asn Gln Trp Phe Ile Pro Ala Val Arg Gly Asp Ile Pro Pro 
65                  70                  75                  80  


Gly Cys Ala Ala Tyr Gly Phe Val Cys Asp Gly Thr Arg Leu Leu Val 
                85                  90                  95      


Phe Gly Gly Met Val Glu Tyr Gly Lys Tyr Ser Asn Asp Leu Tyr Glu 
            100                 105                 110         


Leu Gln Ala Ser Arg Trp Glu Trp Lys Arg Leu Lys Ala Lys Thr Pro 
        115                 120                 125             


Lys Asn Gly Pro Pro Pro Cys Pro Arg Leu Gly His Ser Phe Ser Leu 
    130                 135                 140                 


Val Gly Asn Lys Cys Tyr Leu Phe Gly Gly Leu Ala Asn Asp Ser Glu 
145                 150                 155                 160 


Asp Pro Lys Asn Asn Ile Pro Arg Tyr Leu Asn Asp Leu Tyr Ile Leu 
                165                 170                 175     


Glu Leu Arg Pro Gly Ser Gly Val Val Ala Trp Asp Ile Pro Ile Thr 
            180                 185                 190         


Tyr Gly Val Leu Pro Pro Pro Arg Glu Ser His Thr Ala Val Val Tyr 
        195                 200                 205             


Thr Glu Lys Asp Asn Lys Lys Ser Lys Leu Val Ile Tyr Gly Gly Met 
    210                 215                 220                 


Ser Gly Cys Arg Leu Gly Asp Leu Trp Thr Leu Asp Ile Asp Thr Leu 
225                 230                 235                 240 


Thr Trp Asn Lys Pro Ser Leu Ser Gly Val Ala Pro Leu Pro Arg Ser 
                245                 250                 255     


Leu His Ser Ala Thr Thr Ile Gly Asn Lys Met Tyr Val Phe Gly Gly 
            260                 265                 270         


Trp Val Pro Leu Val Met Asp Asp Val Lys Val Ala Thr His Glu Lys 
        275                 280                 285             


Glu Trp Lys Cys Thr Asn Thr Leu Ala Cys Leu Asn Leu Asp Thr Met 
    290                 295                 300                 


Ala Trp Glu Thr Ile Leu Met Asp Thr Leu Glu Asp Asn Ile Pro Arg 
305                 310                 315                 320 


Ala Arg Ala Gly His Cys Ala Val Ala Ile Asn Thr Arg Leu Tyr Ile 
                325                 330                 335     


Trp Ser Gly Arg Asp Gly Tyr Arg Lys Ala Trp Asn Asn Gln Val Cys 
            340                 345                 350         


Cys Lys Asp Leu Trp Tyr Leu Glu Thr Glu Lys Pro Pro Pro Pro Ala 
        355                 360                 365             


Arg Val Gln Leu Val Arg Ala Asn Thr Asn Ser Leu Glu Val Ser Trp 
    370                 375                 380                 


Gly Ala Val Ala Thr Ala Asp Ser Tyr Leu Leu Gln Leu Gln Lys Tyr 
385                 390                 395                 400 


Asp Ile Pro Ala Thr Ala Ala Thr Ala Thr Ser Pro Thr Pro Asn Pro 
                405                 410                 415     


Val Pro Ser Val Pro Ala Asn Pro Pro Lys Ser Pro Ala Pro Ala Ala 
            420                 425                 430         


Ala Ala Pro Ala Val Gln Pro Leu Thr Gln Val Gly Ile Thr Leu Leu 
        435                 440                 445             


Pro Gln Ala Ala Pro Ala Pro Pro Thr Thr Thr Thr Ile Gln Val Leu 
    450                 455                 460                 


Pro Thr Val Pro Gly Ser Ser Ile Ser Val Pro Thr Ala Ala Arg Thr 
465                 470                 475                 480 


Gln Gly Val Pro Ala Val Leu Lys Val Thr Gly Pro Gln Ala Thr Thr 
                485                 490                 495     


Gly Thr Pro Leu Val Thr Met Arg Pro Ala Ser Gln Ala Gly Lys Ala 
            500                 505                 510         


Pro Val Thr Val Thr Ser Leu Pro Ala Gly Val Arg Met Val Val Pro 
        515                 520                 525             


Thr Gln Ser Ala Gln Gly Thr Val Ile Gly Ser Ser Pro Gln Met Ser 
    530                 535                 540                 


Gly Met Ala Ala Leu Ala Ala Ala Ala Ala Ala Thr Gln Lys Ile Pro 
545                 550                 555                 560 


Pro Ser Ser Ala Pro Thr Val Leu Ser Val Pro Ala Gly Thr Thr Ile 
                565                 570                 575     


Val Lys Thr Met Ala Val Thr Pro Gly Thr Thr Thr Leu Pro Ala Thr 
            580                 585                 590         


Val Lys Val Ala Ser Ser Pro Val Met Val Ser Asn Pro Ala Thr Arg 
        595                 600                 605             


Met Leu Lys Thr Ala Ala Ala Gln Val Gly Thr Ser Val Ser Ser Ala 
    610                 615                 620                 


Thr Asn Thr Ser Thr Arg Pro Ile Ile Thr Val His Lys Ser Gly Thr 
625                 630                 635                 640 


Val Thr Val Ala Gln Gln Ala Gln Val Val Thr Thr Val Val Gly Gly 
                645                 650                 655     


Val Thr Lys Thr Ile Thr Leu Val Lys Ser Pro Ile Ser Val Pro Gly 
            660                 665                 670         


Gly Ser Ala Leu Ile Ser Asn Leu Gly Lys Val Met Ser Val Val Gln 
        675                 680                 685             


Thr Lys Pro Val Gln Thr Ser Ala Val Thr Gly Gln Ala Ser Thr Gly 
    690                 695                 700                 


Pro Val Thr Gln Ile Ile Gln Thr Lys Gly Pro Leu Pro Ala Gly Thr 
705                 710                 715                 720 


Ile Leu Lys Leu Val Thr Ser Ala Asp Gly Lys Pro Thr Thr Ile Ile 
                725                 730                 735     


Thr Thr Thr Gln Ala Ser Gly Ala Gly Thr Lys Pro Thr Ile Leu Gly 
            740                 745                 750         


Ile Ser Ser Val Ser Pro Ser Thr Thr Lys Pro Gly Thr Thr Thr Ile 
        755                 760                 765             


Ile Lys Thr Ile Pro Met Ser Ala Ile Ile Thr Gln Ala Gly Ala Thr 
    770                 775                 780                 


Gly Val Thr Ser Ser Pro Gly Ile Lys Ser Pro Ile Thr Ile Ile Thr 
785                 790                 795                 800 


Thr Lys Val Met Thr Ser Gly Thr Gly Ala Pro Ala Lys Ile Ile Thr 
                805                 810                 815     


Ala Val Pro Lys Ile Ala Thr Gly His Gly Gln Gln Gly Val Thr Gln 
            820                 825                 830         


Val Val Leu Lys Gly Ala Pro Gly Gln Pro Gly Thr Ile Leu Arg Thr 
        835                 840                 845             


Val Pro Met Gly Gly Val Arg Leu Val Thr Pro Val Thr Val Ser Ala 
    850                 855                 860                 


Val Lys Pro Ala Val Thr Thr Leu Val Val Lys Gly Thr Thr Gly Val 
865                 870                 875                 880 


Thr Thr Leu Gly Thr Val Thr Gly Thr Val Ser Thr Ser Leu Ala Gly 
                885                 890                 895     


Ala Gly Gly His Ser Thr Ser Ala Ser Leu Ala Thr Pro Ile Thr Thr 
            900                 905                 910         


Leu Gly Thr Ile Ala Thr Leu Ser Ser Gln Val Ile Asn Pro Thr Ala 
        915                 920                 925             


Ile Thr Val Ser Ala Ala Gln Thr Thr Leu Thr Ala Ala Gly Gly Leu 
    930                 935                 940                 


Thr Thr Pro Thr Ile Thr Met Gln Pro Val Ser Gln Pro Thr Gln Val 
945                 950                 955                 960 


Thr Leu Ile Thr Ala Pro Ser Gly Val Glu Ala Gln Pro Val His Asp 
                965                 970                 975     


Leu Pro Val Ser Ile Leu Ala Ser Pro Thr Thr Glu Gln Pro Thr Ala 
            980                 985                 990         


Thr Val Thr Ile Ala Asp Ser Gly  Gln Gly Asp Val Gln  Pro Gly Thr 
        995                 1000                 1005             


Val Thr  Leu Val Cys Ser Asn  Pro Pro Cys Glu Thr  His Glu Thr 
    1010                 1015                 1020             


Gly Thr  Thr Asn Thr Ala Thr  Thr Thr Val Val Ala  Asn Leu Gly 
    1025                 1030                 1035             


Gly His  Pro Gln Pro Thr Gln  Val Gln Phe Val Cys  Asp Arg Gln 
    1040                 1045                 1050             


Glu Ala  Ala Ala Ser Leu Val  Thr Ser Thr Val Gly  Gln Gln Asn 
    1055                 1060                 1065             


Gly Ser  Val Val Arg Val Cys  Ser Asn Pro Pro Cys  Glu Thr His 
    1070                 1075                 1080             


Glu Thr  Gly Thr Thr Asn Thr  Ala Thr Thr Ala Thr  Ser Asn Met 
    1085                 1090                 1095             


Ala Gly  Gln His Gly Cys Ser  Asn Pro Pro Cys Glu  Thr His Glu 
    1100                 1105                 1110             


Thr Gly  Thr Thr Asn Thr Ala  Thr Thr Ala Met Ser  Ser Val Gly 
    1115                 1120                 1125             


Ala Asn  His Gln Arg Asp Ala  Arg Arg Ala Cys Ala  Ala Gly Thr 
    1130                 1135                 1140             


Pro Ala  Val Ile Arg Ile Ser  Val Ala Thr Gly Ala  Leu Glu Ala 
    1145                 1150                 1155             


Ala Gln  Gly Ser Lys Ser Gln  Cys Gln Thr Arg Gln  Thr Ser Ala 
    1160                 1165                 1170             


Thr Ser  Thr Thr Met Thr Val  Met Ala Thr Gly Ala  Pro Cys Ser 
    1175                 1180                 1185             


Ala Gly  Pro Leu Leu Gly Pro  Ser Met Ala Arg Glu  Pro Gly Gly 
    1190                 1195                 1200             


Arg Ser  Pro Ala Phe Val Gln  Leu Ala Pro Leu Ser  Ser Lys Val 
    1205                 1210                 1215             


Arg Leu  Ser Ser Pro Ser Ile  Lys Asp Leu Pro Ala  Gly Arg His 
    1220                 1225                 1230             


Ser His  Ala Val Ser Thr Ala  Ala Met Thr Arg Ser  Ser Val Gly 
    1235                 1240                 1245             


Ala Gly  Glu Pro Arg Met Ala  Pro Val Cys Glu Ser  Leu Gln Gly 
    1250                 1255                 1260             


Gly Ser  Pro Ser Thr Thr Val  Thr Val Thr Ala Leu  Glu Ala Leu 
    1265                 1270                 1275             


Leu Cys  Pro Ser Ala Thr Val  Thr Gln Val Cys Ser  Asn Pro Pro 
    1280                 1285                 1290             


Cys Glu  Thr His Glu Thr Gly  Thr Thr Asn Thr Ala  Thr Thr Ser 
    1295                 1300                 1305             


Asn Ala  Gly Ser Ala Gln Arg  Val Cys Ser Asn Pro  Pro Cys Glu 
    1310                 1315                 1320             


Thr His  Glu Thr Gly Thr Thr  His Thr Ala Thr Thr  Ala Thr Ser 
    1325                 1330                 1335             


Asn Gly  Gly Thr Gly Gln Pro  Glu Gly Gly Gln Gln  Pro Pro Ala 
    1340                 1345                 1350             


Gly Arg  Pro Cys Glu Thr His  Gln Thr Thr Ser Thr  Gly Thr Thr 
    1355                 1360                 1365             


Met Ser  Val Ser Val Gly Ala  Leu Leu Pro Asp Ala  Thr Ser Ser 
    1370                 1375                 1380             


His Arg  Thr Val Glu Ser Gly  Leu Glu Val Ala Ala  Ala Pro Ser 
    1385                 1390                 1395             


Val Thr  Pro Gln Ala Gly Thr  Ala Leu Leu Ala Pro  Phe Pro Thr 
    1400                 1405                 1410             


Gln Arg  Val Cys Ser Asn Pro  Pro Cys Glu Thr His  Glu Thr Gly 
    1415                 1420                 1425             


Thr Thr  His Thr Ala Thr Thr  Val Thr Ser Asn Met  Ser Ser Asn 
    1430                 1435                 1440             


Gln Asp  Pro Pro Pro Ala Ala  Ser Asp Gln Gly Glu  Val Glu Ser 
    1445                 1450                 1455             


Thr Gln  Gly Asp Ser Val Asn  Ile Thr Ser Ser Ser  Ala Ile Thr 
    1460                 1465                 1470             


Thr Thr  Val Ser Ser Thr Leu  Thr Arg Ala Val Thr  Thr Val Thr 
    1475                 1480                 1485             


Gln Ser  Thr Pro Val Pro Gly  Pro Ser Val Pro Pro  Pro Glu Glu 
    1490                 1495                 1500             


Leu Gln  Val Ser Pro Gly Pro  Arg Gln Gln Leu Pro  Pro Arg Gln 
    1505                 1510                 1515             


Leu Leu  Gln Ser Ala Ser Thr  Ala Leu Met Gly Glu  Ser Ala Glu 
    1520                 1525                 1530             


Val Leu  Ser Ala Ser Gln Thr  Pro Glu Leu Pro Ala  Ala Val Asp 
    1535                 1540                 1545             


Leu Ser  Ser Thr Gly Glu Pro  Ser Ser Gly Gln Glu  Ser Ala Gly 
    1550                 1555                 1560             


Ser Ala  Val Val Ala Thr Val  Val Val Gln Pro Pro  Pro Pro Thr 
    1565                 1570                 1575             


Gln Ser  Glu Val Asp Gln Leu  Ser Leu Pro Gln Glu  Leu Met Ala 
    1580                 1585                 1590             


Glu Ala  Gln Ala Gly Thr Thr  Thr Leu Met Val Thr  Gly Leu Thr 
    1595                 1600                 1605             


Pro Glu  Glu Leu Ala Val Thr  Ala Ala Ala Glu Ala  Ala Ala Gln 
    1610                 1615                 1620             


Ala Ala  Ala Thr Glu Glu Ala  Gln Ala Leu Ala Ile  Gln Ala Val 
    1625                 1630                 1635             


Leu Gln  Ala Ala Gln Gln Ala  Val Met Gly Thr Gly  Glu Pro Met 
    1640                 1645                 1650             


Asp Thr  Ser Glu Ala Ala Ala  Thr Val Thr Gln Ala  Glu Leu Gly 
    1655                 1660                 1665             


His Leu  Ser Ala Glu Gly Gln  Glu Gly Gln Ala Thr  Thr Ile Pro 
    1670                 1675                 1680             


Ile Val  Leu Thr Gln Gln Glu  Leu Ala Ala Leu Val  Gln Gln Gln 
    1685                 1690                 1695             


Gln Leu  Gln Glu Ala Gln Ala  Gln Gln Gln His His  His Leu Pro 
    1700                 1705                 1710             


Thr Glu  Ala Leu Ala Pro Ala  Asp Ser Leu Asn Asp  Pro Ala Ile 
    1715                 1720                 1725             


Glu Ser  Asn Cys Leu Asn Glu  Leu Ala Gly Thr Val  Pro Ser Thr 
    1730                 1735                 1740             


Val Ala  Leu Leu Pro Ser Thr  Ala Thr Glu Ser Leu  Ala Pro Ser 
    1745                 1750                 1755             


Asn Thr  Phe Val Ala Pro Gln  Pro Val Val Val Ala  Ser Pro Ala 
    1760                 1765                 1770             


Lys Leu  Gln Ala Ala Ala Thr  Leu Thr Glu Val Ala  Asn Gly Ile 
    1775                 1780                 1785             


Glu Ser  Leu Gly Val Lys Pro  Asp Leu Pro Pro Pro  Pro Ser Lys 
    1790                 1795                 1800             


Ala Pro  Met Lys Lys Glu Asn  Gln Trp Phe Asp Val  Gly Val Ile 
    1805                 1810                 1815             


Lys Gly  Thr Asn Val Met Val  Thr His Tyr Phe Leu  Pro Pro Asp 
    1820                 1825                 1830             


Asp Ala  Val Pro Ser Asp Asp  Asp Leu Gly Thr Val  Pro Asp Tyr 
    1835                 1840                 1845             


Asn Gln  Leu Lys Lys Gln Glu  Leu Gln Pro Gly Thr  Ala Tyr Lys 
    1850                 1855                 1860             


Phe Arg  Val Ala Gly Ile Asn  Ala Cys Gly Arg Gly  Pro Phe Ser 
    1865                 1870                 1875             


Glu Ile  Ser Ala Phe Lys Thr  Cys Leu Pro Gly Phe  Pro Gly Ala 
    1880                 1885                 1890             


Pro Cys  Ala Ile Lys Ile Ser  Lys Ser Pro Asp Gly  Ala His Leu 
    1895                 1900                 1905             


Thr Trp  Glu Pro Pro Ser Val  Thr Ser Gly Lys Ile  Ile Glu Tyr 
    1910                 1915                 1920             


Ser Val  Tyr Leu Ala Ile Gln  Ser Ser Gln Ala Gly  Gly Glu Leu 
    1925                 1930                 1935             


Lys Ser  Ser Thr Pro Ala Gln  Leu Ala Phe Met Arg  Val Tyr Cys 
    1940                 1945                 1950             


Gly Pro  Ser Pro Ser Cys Leu  Val Gln Ser Ser Ser  Leu Ser Asn 
    1955                 1960                 1965             


Ala His  Ile Asp Tyr Thr Thr  Lys Pro Ala Ile Ile  Phe Arg Ile 
    1970                 1975                 1980             


Ala Ala  Arg Asn Glu Lys Gly  Tyr Gly Pro Ala Thr  Gln Val Arg 
    1985                 1990                 1995             


Trp Leu  Gln Glu Thr Ser Lys  Asp Ser Ser Gly Thr  Lys Pro Ala 
    2000                 2005                 2010             


Asn Lys  Arg Pro Met Ser Ser  Pro Glu Met Lys Ser  Ala Pro Lys 
    2015                 2020                 2025             


Lys Ser  Lys Ala Asp Gly Gln  
    2030                 2035 


<210>  1332
<211>  1268
<212>  PRT
<213>  Human

<400>  1332

Met Ser Ser Val Ala Val Leu Thr Gln Glu Ser Phe Ala Glu His Arg 
1               5                   10                  15      


Ser Gly Leu Val Pro Gln Gln Ile Lys Val Ala Thr Leu Asn Ser Glu 
            20                  25                  30          


Glu Glu Ser Asp Pro Pro Thr Tyr Lys Asp Ala Phe Pro Pro Leu Pro 
        35                  40                  45              


Glu Lys Ala Ala Cys Leu Glu Ser Ala Gln Glu Pro Ala Gly Ala Trp 
    50                  55                  60                  


Gly Asn Lys Ile Arg Pro Ile Lys Ala Ser Val Ile Thr Gln Val Phe 
65                  70                  75                  80  


His Val Pro Leu Glu Glu Arg Lys Tyr Lys Asp Met Asn Gln Phe Gly 
                85                  90                  95      


Glu Gly Glu Gln Ala Lys Ile Cys Leu Glu Ile Met Gln Arg Thr Gly 
            100                 105                 110         


Ala His Leu Glu Leu Ser Leu Ala Lys Asp Gln Gly Leu Ser Ile Met 
        115                 120                 125             


Val Ser Gly Lys Leu Asp Ala Val Met Lys Ala Arg Lys Asp Ile Val 
    130                 135                 140                 


Ala Arg Leu Gln Thr Gln Ala Ser Ala Thr Val Ala Ile Pro Lys Glu 
145                 150                 155                 160 


His His Arg Phe Val Ile Gly Lys Asn Gly Glu Lys Leu Gln Asp Leu 
                165                 170                 175     


Glu Leu Lys Thr Ala Thr Lys Ile Gln Ile Pro Arg Pro Asp Asp Pro 
            180                 185                 190         


Ser Asn Gln Ile Lys Ile Thr Gly Thr Lys Glu Gly Ile Glu Lys Ala 
        195                 200                 205             


Arg His Glu Val Leu Leu Ile Ser Ala Glu Gln Asp Lys Arg Ala Val 
    210                 215                 220                 


Glu Arg Leu Glu Val Glu Lys Ala Phe His Pro Phe Ile Ala Gly Pro 
225                 230                 235                 240 


Tyr Asn Arg Leu Val Gly Glu Ile Met Gln Glu Thr Gly Thr Arg Ile 
                245                 250                 255     


Asn Ile Pro Pro Pro Ser Val Asn Arg Thr Glu Ile Val Phe Thr Gly 
            260                 265                 270         


Glu Lys Glu Gln Leu Ala Gln Ala Val Ala Arg Ile Lys Lys Ile Tyr 
        275                 280                 285             


Glu Glu Lys Lys Lys Lys Thr Thr Thr Ile Ala Val Glu Val Lys Lys 
    290                 295                 300                 


Ser Gln His Lys Tyr Val Ile Gly Pro Lys Gly Asn Ser Leu Gln Glu 
305                 310                 315                 320 


Ile Leu Glu Arg Thr Gly Val Ser Val Glu Ile Pro Pro Ser Asp Ser 
                325                 330                 335     


Ile Ser Glu Thr Val Ile Leu Arg Gly Glu Pro Glu Lys Leu Gly Gln 
            340                 345                 350         


Ala Leu Thr Glu Val Tyr Ala Lys Ala Asn Ser Phe Thr Val Ser Ser 
        355                 360                 365             


Val Ala Ala Pro Ser Trp Leu His Arg Phe Ile Ile Gly Lys Lys Gly 
    370                 375                 380                 


Gln Asn Leu Ala Lys Ile Thr Gln Gln Met Pro Lys Val His Ile Glu 
385                 390                 395                 400 


Phe Thr Glu Gly Glu Asp Lys Ile Thr Leu Glu Gly Pro Thr Glu Asp 
                405                 410                 415     


Val Asn Val Ala Gln Glu Gln Ile Glu Gly Met Val Lys Asp Leu Ile 
            420                 425                 430         


Asn Arg Met Asp Tyr Val Glu Ile Asn Ile Asp His Lys Phe His Arg 
        435                 440                 445             


His Leu Ile Gly Lys Ser Gly Ala Asn Ile Asn Arg Ile Lys Asp Gln 
    450                 455                 460                 


Tyr Lys Val Ser Val Arg Ile Pro Pro Asp Ser Glu Lys Ser Asn Leu 
465                 470                 475                 480 


Ile Arg Ile Glu Gly Asp Pro Gln Gly Val Gln Gln Ala Lys Arg Glu 
                485                 490                 495     


Leu Leu Glu Leu Ala Ser Arg Met Glu Asn Glu Arg Thr Lys Asp Leu 
            500                 505                 510         


Ile Ile Glu Gln Arg Phe His Arg Thr Ile Ile Gly Gln Lys Gly Glu 
        515                 520                 525             


Arg Ile Arg Glu Ile Arg Asp Lys Phe Pro Glu Val Ile Ile Asn Phe 
    530                 535                 540                 


Pro Asp Pro Ala Gln Lys Ser Asp Ile Val Gln Leu Arg Gly Pro Lys 
545                 550                 555                 560 


Asn Glu Val Glu Lys Cys Thr Lys Tyr Met Gln Lys Met Val Ala Asp 
                565                 570                 575     


Leu Val Glu Asn Ser Tyr Ser Ile Ser Val Pro Ile Phe Lys Gln Phe 
            580                 585                 590         


His Lys Asn Ile Ile Gly Lys Gly Gly Ala Asn Ile Lys Lys Ile Arg 
        595                 600                 605             


Glu Glu Ser Asn Thr Lys Ile Asp Leu Pro Ala Glu Asn Ser Asn Ser 
    610                 615                 620                 


Glu Thr Ile Ile Ile Thr Gly Lys Arg Ala Asn Cys Glu Ala Ala Arg 
625                 630                 635                 640 


Ser Arg Ile Leu Ser Ile Gln Lys Asp Leu Ala Asn Ile Ala Glu Val 
                645                 650                 655     


Glu Val Ser Ile Pro Ala Lys Leu His Asn Ser Leu Ile Gly Thr Lys 
            660                 665                 670         


Gly Arg Leu Ile Arg Ser Ile Met Glu Glu Cys Gly Gly Val His Ile 
        675                 680                 685             


His Phe Pro Val Glu Gly Ser Gly Ser Asp Thr Val Val Ile Arg Gly 
    690                 695                 700                 


Pro Ser Ser Asp Val Glu Lys Ala Lys Lys Gln Leu Leu His Leu Ala 
705                 710                 715                 720 


Glu Glu Lys Gln Thr Lys Ser Phe Thr Val Asp Ile Arg Ala Lys Pro 
                725                 730                 735     


Glu Tyr His Lys Phe Leu Ile Gly Lys Gly Gly Gly Lys Ile Arg Lys 
            740                 745                 750         


Val Arg Asp Ser Thr Gly Ala Arg Val Ile Phe Pro Ala Ala Glu Asp 
        755                 760                 765             


Lys Asp Gln Asp Leu Ile Thr Ile Ile Gly Lys Glu Asp Ala Val Arg 
    770                 775                 780                 


Glu Ala Gln Lys Glu Leu Glu Ala Leu Ile Gln Asn Leu Asp Asn Val 
785                 790                 795                 800 


Val Glu Asp Ser Met Leu Val Asp Pro Lys His His Arg His Phe Val 
                805                 810                 815     


Ile Arg Arg Gly Gln Val Leu Arg Glu Ile Ala Glu Glu Tyr Gly Gly 
            820                 825                 830         


Val Met Val Ser Phe Pro Arg Ser Gly Thr Gln Ser Asp Lys Val Thr 
        835                 840                 845             


Leu Lys Gly Ala Lys Asp Cys Val Glu Ala Ala Lys Lys Arg Ile Gln 
    850                 855                 860                 


Glu Ile Ile Glu Asp Leu Glu Ala Gln Val Thr Leu Glu Cys Ala Ile 
865                 870                 875                 880 


Pro Gln Lys Phe His Arg Ser Val Met Gly Pro Lys Gly Ser Arg Ile 
                885                 890                 895     


Gln Gln Ile Thr Arg Asp Phe Ser Val Gln Ile Lys Phe Pro Asp Arg 
            900                 905                 910         


Glu Glu Asn Ala Val His Ser Thr Glu Pro Val Val Gln Glu Asn Gly 
        915                 920                 925             


Asp Glu Ala Gly Glu Gly Arg Glu Ala Lys Asp Cys Asp Pro Gly Ser 
    930                 935                 940                 


Pro Arg Arg Cys Asp Ile Ile Ile Ile Ser Gly Arg Lys Glu Lys Cys 
945                 950                 955                 960 


Glu Ala Ala Lys Glu Ala Leu Glu Ala Leu Val Pro Val Thr Ile Glu 
                965                 970                 975     


Val Glu Val Pro Phe Asp Leu His Arg Tyr Val Ile Gly Gln Lys Gly 
            980                 985                 990         


Ser Gly Ile Arg Lys Met Met Asp  Glu Phe Glu Val Asn  Ile His Val 
        995                 1000                 1005             


Pro Ala  Pro Glu Leu Gln Ser  Asp Ile Ile Ala Ile  Thr Gly Leu 
    1010                 1015                 1020             


Ala Ala  Asn Leu Asp Arg Ala  Lys Ala Gly Leu Leu  Glu Arg Val 
    1025                 1030                 1035             


Lys Glu  Leu Gln Ala Glu Gln  Glu Asp Arg Ala Leu  Arg Ser Phe 
    1040                 1045                 1050             


Lys Leu  Ser Val Thr Val Asp  Pro Lys Tyr His Pro  Lys Ile Ile 
    1055                 1060                 1065             


Gly Arg  Lys Gly Ala Val Ile  Thr Gln Ile Arg Leu  Glu His Asp 
    1070                 1075                 1080             


Val Asn  Ile Gln Phe Pro Asp  Lys Asp Asp Gly Asn  Gln Pro Gln 
    1085                 1090                 1095             


Asp Gln  Ile Thr Ile Thr Gly  Tyr Glu Lys Asn Thr  Glu Ala Ala 
    1100                 1105                 1110             


Arg Asp  Ala Ile Leu Arg Ile  Val Gly Glu Leu Glu  Gln Met Val 
    1115                 1120                 1125             


Ser Glu  Asp Val Pro Leu Asp  His Arg Val His Ala  Arg Ile Ile 
    1130                 1135                 1140             


Gly Ala  Arg Gly Lys Ala Ile  Arg Lys Ile Met Asp  Glu Phe Lys 
    1145                 1150                 1155             


Val Asp  Ile Arg Phe Pro Gln  Ser Gly Ala Pro Asp  Pro Asn Cys 
    1160                 1165                 1170             


Val Thr  Val Thr Gly Leu Pro  Glu Asn Val Glu Glu  Ala Ile Asp 
    1175                 1180                 1185             


His Ile  Leu Asn Leu Glu Glu  Glu Tyr Leu Ala Asp  Val Val Asp 
    1190                 1195                 1200             


Ser Glu  Ala Leu Gln Val Tyr  Met Lys Pro Pro Ala  His Glu Glu 
    1205                 1210                 1215             


Ala Lys  Ala Pro Ser Arg Gly  Phe Val Val Arg Asp  Ala Pro Trp 
    1220                 1225                 1230             


Thr Ala  Ser Ser Ser Glu Lys  Ala Pro Asp Met Ser  Ser Ser Glu 
    1235                 1240                 1245             


Glu Phe  Pro Ser Phe Gly Ala  Gln Val Ala Pro Lys  Thr Leu Pro 
    1250                 1255                 1260             


Trp Gly  Pro Lys Arg 
    1265             


<210>  1333
<211>  355
<212>  PRT
<213>  Human

<400>  1333

Met Ser Glu Glu Gln Phe Gly Gly Asp Gly Ala Ala Ala Ala Ala Thr 
1               5                   10                  15      


Ala Ala Val Gly Gly Ser Ala Gly Glu Gln Glu Gly Ala Met Val Ala 
            20                  25                  30          


Ala Thr Gln Gly Ala Ala Ala Ala Ala Gly Ser Gly Ala Gly Thr Gly 
        35                  40                  45              


Gly Gly Thr Ala Ser Gly Gly Thr Glu Gly Gly Ser Ala Glu Ser Glu 
    50                  55                  60                  


Gly Ala Lys Ile Asp Ala Ser Lys Asn Glu Glu Asp Glu Gly His Ser 
65                  70                  75                  80  


Asn Ser Ser Pro Arg His Ser Glu Ala Ala Thr Ala Gln Arg Glu Glu 
                85                  90                  95      


Trp Lys Met Phe Ile Gly Gly Leu Ser Trp Asp Thr Thr Lys Lys Asp 
            100                 105                 110         


Leu Lys Asp Tyr Phe Ser Lys Phe Gly Glu Val Val Asp Cys Thr Leu 
        115                 120                 125             


Lys Leu Asp Pro Ile Thr Gly Arg Ser Arg Gly Phe Gly Phe Val Leu 
    130                 135                 140                 


Phe Lys Glu Ser Glu Ser Val Asp Lys Val Met Asp Gln Lys Glu His 
145                 150                 155                 160 


Lys Leu Asn Gly Lys Val Ile Asp Pro Lys Arg Ala Lys Ala Met Lys 
                165                 170                 175     


Thr Lys Glu Pro Val Lys Lys Ile Phe Val Gly Gly Leu Ser Pro Asp 
            180                 185                 190         


Thr Pro Glu Glu Lys Ile Arg Glu Tyr Phe Gly Gly Phe Gly Glu Val 
        195                 200                 205             


Glu Ser Ile Glu Leu Pro Met Asp Asn Lys Thr Asn Lys Arg Arg Gly 
    210                 215                 220                 


Phe Cys Phe Ile Thr Phe Lys Glu Glu Glu Pro Val Lys Lys Ile Met 
225                 230                 235                 240 


Glu Lys Lys Tyr His Asn Val Gly Leu Ser Lys Cys Glu Ile Lys Val 
                245                 250                 255     


Ala Met Ser Lys Glu Gln Tyr Gln Gln Gln Gln Gln Trp Gly Ser Arg 
            260                 265                 270         


Gly Gly Phe Ala Gly Arg Ala Arg Gly Arg Gly Gly Gly Pro Ser Gln 
        275                 280                 285             


Asn Trp Asn Gln Gly Tyr Ser Asn Tyr Trp Asn Gln Gly Tyr Gly Asn 
    290                 295                 300                 


Tyr Gly Tyr Asn Ser Gln Gly Tyr Gly Gly Tyr Gly Gly Tyr Asp Tyr 
305                 310                 315                 320 


Thr Gly Tyr Asn Asn Tyr Tyr Gly Tyr Gly Asp Tyr Ser Asn Gln Gln 
                325                 330                 335     


Ser Gly Tyr Gly Lys Val Ser Arg Arg Gly Gly His Gln Asn Ser Tyr 
            340                 345                 350         


Lys Pro Tyr 
        355 


<210>  1334
<211>  732
<212>  PRT
<213>  Human

<400>  1334

Met Pro Glu Glu Thr Gln Thr Gln Asp Gln Pro Met Glu Glu Glu Glu 
1               5                   10                  15      


Val Glu Thr Phe Ala Phe Gln Ala Glu Ile Ala Gln Leu Met Ser Leu 
            20                  25                  30          


Ile Ile Asn Thr Phe Tyr Ser Asn Lys Glu Ile Phe Leu Arg Glu Leu 
        35                  40                  45              


Ile Ser Asn Ser Ser Asp Ala Leu Asp Lys Ile Arg Tyr Glu Ser Leu 
    50                  55                  60                  


Thr Asp Pro Ser Lys Leu Asp Ser Gly Lys Glu Leu His Ile Asn Leu 
65                  70                  75                  80  


Ile Pro Asn Lys Gln Asp Arg Thr Leu Thr Ile Val Asp Thr Gly Ile 
                85                  90                  95      


Gly Met Thr Lys Ala Asp Leu Ile Asn Asn Leu Gly Thr Ile Ala Lys 
            100                 105                 110         


Ser Gly Thr Lys Ala Phe Met Glu Ala Leu Gln Ala Gly Ala Asp Ile 
        115                 120                 125             


Ser Met Ile Gly Gln Phe Gly Val Gly Phe Tyr Ser Ala Tyr Leu Val 
    130                 135                 140                 


Ala Glu Lys Val Thr Val Ile Thr Lys His Asn Asp Asp Glu Gln Tyr 
145                 150                 155                 160 


Ala Trp Glu Ser Ser Ala Gly Gly Ser Phe Thr Val Arg Thr Asp Thr 
                165                 170                 175     


Gly Glu Pro Met Gly Arg Gly Thr Lys Val Ile Leu His Leu Lys Glu 
            180                 185                 190         


Asp Gln Thr Glu Tyr Leu Glu Glu Arg Arg Ile Lys Glu Ile Val Lys 
        195                 200                 205             


Lys His Ser Gln Phe Ile Gly Tyr Pro Ile Thr Leu Phe Val Glu Lys 
    210                 215                 220                 


Glu Arg Asp Lys Glu Val Ser Asp Asp Glu Ala Glu Glu Lys Glu Asp 
225                 230                 235                 240 


Lys Glu Glu Glu Lys Glu Lys Glu Glu Lys Glu Ser Glu Asp Lys Pro 
                245                 250                 255     


Glu Ile Glu Asp Val Gly Ser Asp Glu Glu Glu Glu Lys Lys Asp Gly 
            260                 265                 270         


Asp Lys Lys Lys Lys Lys Lys Ile Lys Glu Lys Tyr Ile Asp Gln Glu 
        275                 280                 285             


Glu Leu Asn Lys Thr Lys Pro Ile Trp Thr Arg Asn Pro Asp Asp Ile 
    290                 295                 300                 


Thr Asn Glu Glu Tyr Gly Glu Phe Tyr Lys Ser Leu Thr Asn Asp Trp 
305                 310                 315                 320 


Glu Asp His Leu Ala Val Lys His Phe Ser Val Glu Gly Gln Leu Glu 
                325                 330                 335     


Phe Arg Ala Leu Leu Phe Val Pro Arg Arg Ala Pro Phe Asp Leu Phe 
            340                 345                 350         


Glu Asn Arg Lys Lys Lys Asn Asn Ile Lys Leu Tyr Val Arg Arg Val 
        355                 360                 365             


Phe Ile Met Asp Asn Cys Glu Glu Leu Ile Pro Glu Tyr Leu Asn Phe 
    370                 375                 380                 


Ile Arg Gly Val Val Asp Ser Glu Asp Leu Pro Leu Asn Ile Ser Arg 
385                 390                 395                 400 


Glu Met Leu Gln Gln Ser Lys Ile Leu Lys Val Ile Arg Lys Asn Leu 
                405                 410                 415     


Val Lys Lys Cys Leu Glu Leu Phe Thr Glu Leu Ala Glu Asp Lys Glu 
            420                 425                 430         


Asn Tyr Lys Lys Phe Tyr Glu Gln Phe Ser Lys Asn Ile Lys Leu Gly 
        435                 440                 445             


Ile His Glu Asp Ser Gln Asn Arg Lys Lys Leu Ser Glu Leu Leu Arg 
    450                 455                 460                 


Tyr Tyr Thr Ser Ala Ser Gly Asp Glu Met Val Ser Leu Lys Asp Tyr 
465                 470                 475                 480 


Cys Thr Arg Met Lys Glu Asn Gln Lys His Ile Tyr Tyr Ile Thr Gly 
                485                 490                 495     


Glu Thr Lys Asp Gln Val Ala Asn Ser Ala Phe Val Glu Arg Leu Arg 
            500                 505                 510         


Lys His Gly Leu Glu Val Ile Tyr Met Ile Glu Pro Ile Asp Glu Tyr 
        515                 520                 525             


Cys Val Gln Gln Leu Lys Glu Phe Glu Gly Lys Thr Leu Val Ser Val 
    530                 535                 540                 


Thr Lys Glu Gly Leu Glu Leu Pro Glu Asp Glu Glu Glu Lys Lys Lys 
545                 550                 555                 560 


Gln Glu Glu Lys Lys Thr Lys Phe Glu Asn Leu Cys Lys Ile Met Lys 
                565                 570                 575     


Asp Ile Leu Glu Lys Lys Val Glu Lys Val Val Val Ser Asn Arg Leu 
            580                 585                 590         


Val Thr Ser Pro Cys Cys Ile Val Thr Ser Thr Tyr Gly Trp Thr Ala 
        595                 600                 605             


Asn Met Glu Arg Ile Met Lys Ala Gln Ala Leu Arg Asp Asn Ser Thr 
    610                 615                 620                 


Met Gly Tyr Met Ala Ala Lys Lys His Leu Glu Ile Asn Pro Asp His 
625                 630                 635                 640 


Ser Ile Ile Glu Thr Leu Arg Gln Lys Ala Glu Ala Asp Lys Asn Asp 
                645                 650                 655     


Lys Ser Val Lys Asp Leu Val Ile Leu Leu Tyr Glu Thr Ala Leu Leu 
            660                 665                 670         


Ser Ser Gly Phe Ser Leu Glu Asp Pro Gln Thr His Ala Asn Arg Ile 
        675                 680                 685             


Tyr Arg Met Ile Lys Leu Gly Leu Gly Ile Asp Glu Asp Asp Pro Thr 
    690                 695                 700                 


Ala Asp Asp Thr Ser Ala Ala Val Thr Glu Glu Met Pro Pro Leu Glu 
705                 710                 715                 720 


Gly Asp Asp Asp Thr Ser Arg Met Glu Glu Val Asp 
                725                 730         


<210>  1335
<211>  803
<212>  PRT
<213>  Human

<400>  1335

Met Arg Ala Leu Trp Val Leu Gly Leu Cys Cys Val Leu Leu Thr Phe 
1               5                   10                  15      


Gly Ser Val Arg Ala Asp Asp Glu Val Asp Val Asp Gly Thr Val Glu 
            20                  25                  30          


Glu Asp Leu Gly Lys Ser Arg Glu Gly Ser Arg Thr Asp Asp Glu Val 
        35                  40                  45              


Val Gln Arg Glu Glu Glu Ala Ile Gln Leu Asp Gly Leu Asn Ala Ser 
    50                  55                  60                  


Gln Ile Arg Glu Leu Arg Glu Lys Ser Glu Lys Phe Ala Phe Gln Ala 
65                  70                  75                  80  


Glu Val Asn Arg Met Met Lys Leu Ile Ile Asn Ser Leu Tyr Lys Asn 
                85                  90                  95      


Lys Glu Ile Phe Leu Arg Glu Leu Ile Ser Asn Ala Ser Asp Ala Leu 
            100                 105                 110         


Asp Lys Ile Arg Leu Ile Ser Leu Thr Asp Glu Asn Ala Leu Ser Gly 
        115                 120                 125             


Asn Glu Glu Leu Thr Val Lys Ile Lys Cys Asp Lys Glu Lys Asn Leu 
    130                 135                 140                 


Leu His Val Thr Asp Thr Gly Val Gly Met Thr Arg Glu Glu Leu Val 
145                 150                 155                 160 


Lys Asn Leu Gly Thr Ile Ala Lys Ser Gly Thr Ser Glu Phe Leu Asn 
                165                 170                 175     


Lys Met Thr Glu Ala Gln Glu Asp Gly Gln Ser Thr Ser Glu Leu Ile 
            180                 185                 190         


Gly Gln Phe Gly Val Gly Phe Tyr Ser Ala Phe Leu Val Ala Asp Lys 
        195                 200                 205             


Val Ile Val Thr Ser Lys His Asn Asn Asp Thr Gln His Ile Trp Glu 
    210                 215                 220                 


Ser Asp Ser Asn Glu Phe Ser Val Ile Ala Asp Pro Arg Gly Asn Thr 
225                 230                 235                 240 


Leu Gly Arg Gly Thr Thr Ile Thr Leu Val Leu Lys Glu Glu Ala Ser 
                245                 250                 255     


Asp Tyr Leu Glu Leu Asp Thr Ile Lys Asn Leu Val Lys Lys Tyr Ser 
            260                 265                 270         


Gln Phe Ile Asn Phe Pro Ile Tyr Val Trp Ser Ser Lys Thr Glu Thr 
        275                 280                 285             


Val Glu Glu Pro Met Glu Glu Glu Glu Ala Ala Lys Glu Glu Lys Glu 
    290                 295                 300                 


Glu Ser Asp Asp Glu Ala Ala Val Glu Glu Glu Glu Glu Glu Lys Lys 
305                 310                 315                 320 


Pro Lys Thr Lys Lys Val Glu Lys Thr Val Trp Asp Trp Glu Leu Met 
                325                 330                 335     


Asn Asp Ile Lys Pro Ile Trp Gln Arg Pro Ser Lys Glu Val Glu Glu 
            340                 345                 350         


Asp Glu Tyr Lys Ala Phe Tyr Lys Ser Phe Ser Lys Glu Ser Asp Asp 
        355                 360                 365             


Pro Met Ala Tyr Ile His Phe Thr Ala Glu Gly Glu Val Thr Phe Lys 
    370                 375                 380                 


Ser Ile Leu Phe Val Pro Thr Ser Ala Pro Arg Gly Leu Phe Asp Glu 
385                 390                 395                 400 


Tyr Gly Ser Lys Lys Ser Asp Tyr Ile Lys Leu Tyr Val Arg Arg Val 
                405                 410                 415     


Phe Ile Thr Asp Asp Phe His Asp Met Met Pro Lys Tyr Leu Asn Phe 
            420                 425                 430         


Val Lys Gly Val Val Asp Ser Asp Asp Leu Pro Leu Asn Val Ser Arg 
        435                 440                 445             


Glu Thr Leu Gln Gln His Lys Leu Leu Lys Val Ile Arg Lys Lys Leu 
    450                 455                 460                 


Val Arg Lys Thr Leu Asp Met Ile Lys Lys Ile Ala Asp Asp Lys Tyr 
465                 470                 475                 480 


Asn Asp Thr Phe Trp Lys Glu Phe Gly Thr Asn Ile Lys Leu Gly Val 
                485                 490                 495     


Ile Glu Asp His Ser Asn Arg Thr Arg Leu Ala Lys Leu Leu Arg Phe 
            500                 505                 510         


Gln Ser Ser His His Pro Thr Asp Ile Thr Ser Leu Asp Gln Tyr Val 
        515                 520                 525             


Glu Arg Met Lys Glu Lys Gln Asp Lys Ile Tyr Phe Met Ala Gly Ser 
    530                 535                 540                 


Ser Arg Lys Glu Ala Glu Ser Ser Pro Phe Val Glu Arg Leu Leu Lys 
545                 550                 555                 560 


Lys Gly Tyr Glu Val Ile Tyr Leu Thr Glu Pro Val Asp Glu Tyr Cys 
                565                 570                 575     


Ile Gln Ala Leu Pro Glu Phe Asp Gly Lys Arg Phe Gln Asn Val Ala 
            580                 585                 590         


Lys Glu Gly Val Lys Phe Asp Glu Ser Glu Lys Thr Lys Glu Ser Arg 
        595                 600                 605             


Glu Ala Val Glu Lys Glu Phe Glu Pro Leu Leu Asn Trp Met Lys Asp 
    610                 615                 620                 


Lys Ala Leu Lys Asp Lys Ile Glu Lys Ala Val Val Ser Gln Arg Leu 
625                 630                 635                 640 


Thr Glu Ser Pro Cys Ala Leu Val Ala Ser Gln Tyr Gly Trp Ser Gly 
                645                 650                 655     


Asn Met Glu Arg Ile Met Lys Ala Gln Ala Tyr Gln Thr Gly Lys Asp 
            660                 665                 670         


Ile Ser Thr Asn Tyr Tyr Ala Ser Gln Lys Lys Thr Phe Glu Ile Asn 
        675                 680                 685             


Pro Arg His Pro Leu Ile Arg Asp Met Leu Arg Arg Ile Lys Glu Asp 
    690                 695                 700                 


Glu Asp Asp Lys Thr Val Leu Asp Leu Ala Val Val Leu Phe Glu Thr 
705                 710                 715                 720 


Ala Thr Leu Arg Ser Gly Tyr Leu Leu Pro Asp Thr Lys Ala Tyr Gly 
                725                 730                 735     


Asp Arg Ile Glu Arg Met Leu Arg Leu Ser Leu Asn Ile Asp Pro Asp 
            740                 745                 750         


Ala Lys Val Glu Glu Glu Pro Glu Glu Glu Pro Glu Glu Thr Ala Glu 
        755                 760                 765             


Asp Thr Thr Glu Asp Thr Glu Gln Asp Glu Asp Glu Glu Met Asp Val 
    770                 775                 780                 


Gly Thr Asp Glu Glu Glu Glu Thr Ala Lys Glu Ser Thr Ala Glu Lys 
785                 790                 795                 800 


Asp Glu Leu 
            


<210>  1336
<211>  641
<212>  PRT
<213>  Human

<400>  1336

Met Ala Lys Ala Ala Ala Ile Gly Ile Asp Leu Gly Thr Thr Tyr Ser 
1               5                   10                  15      


Cys Val Gly Val Phe Gln His Gly Lys Val Glu Ile Ile Ala Asn Asp 
            20                  25                  30          


Gln Gly Asn Arg Thr Thr Pro Ser Tyr Val Ala Phe Thr Asp Thr Glu 
        35                  40                  45              


Arg Leu Ile Gly Asp Ala Ala Lys Asn Gln Val Ala Leu Asn Pro Gln 
    50                  55                  60                  


Asn Thr Val Phe Asp Ala Lys Arg Leu Ile Gly Arg Lys Phe Gly Asp 
65                  70                  75                  80  


Pro Val Val Gln Ser Asp Met Lys His Trp Pro Phe Gln Val Ile Asn 
                85                  90                  95      


Asp Gly Asp Lys Pro Lys Val Gln Val Ser Tyr Lys Gly Glu Thr Lys 
            100                 105                 110         


Ala Phe Tyr Pro Glu Glu Ile Ser Ser Met Val Leu Thr Lys Met Lys 
        115                 120                 125             


Glu Ile Ala Glu Ala Tyr Leu Gly Tyr Pro Val Thr Asn Ala Val Ile 
    130                 135                 140                 


Thr Val Pro Ala Tyr Phe Asn Asp Ser Gln Arg Gln Ala Thr Lys Asp 
145                 150                 155                 160 


Ala Gly Val Ile Ala Gly Leu Asn Val Leu Arg Ile Ile Asn Glu Pro 
                165                 170                 175     


Thr Ala Ala Ala Ile Ala Tyr Gly Leu Asp Arg Thr Gly Lys Gly Glu 
            180                 185                 190         


Arg Asn Val Leu Ile Phe Asp Leu Gly Gly Gly Thr Phe Asp Val Ser 
        195                 200                 205             


Ile Leu Thr Ile Asp Asp Gly Ile Phe Glu Val Lys Ala Thr Ala Gly 
    210                 215                 220                 


Asp Thr His Leu Gly Gly Glu Asp Phe Asp Asn Arg Leu Val Asn His 
225                 230                 235                 240 


Phe Val Glu Glu Phe Lys Arg Lys His Lys Lys Asp Ile Ser Gln Asn 
                245                 250                 255     


Lys Arg Ala Val Arg Arg Leu Arg Thr Ala Cys Glu Arg Ala Lys Arg 
            260                 265                 270         


Thr Leu Ser Ser Ser Thr Gln Ala Ser Leu Glu Ile Asp Ser Leu Phe 
        275                 280                 285             


Glu Gly Ile Asp Phe Tyr Thr Ser Ile Thr Arg Ala Arg Phe Glu Glu 
    290                 295                 300                 


Leu Cys Ser Asp Leu Phe Arg Ser Thr Leu Glu Pro Val Glu Lys Ala 
305                 310                 315                 320 


Leu Arg Asp Ala Lys Leu Asp Lys Ala Gln Ile His Asp Leu Val Leu 
                325                 330                 335     


Val Gly Gly Ser Thr Arg Ile Pro Lys Val Gln Lys Leu Leu Gln Asp 
            340                 345                 350         


Phe Phe Asn Gly Arg Asp Leu Asn Lys Ser Ile Asn Pro Asp Glu Ala 
        355                 360                 365             


Val Ala Tyr Gly Ala Ala Val Gln Ala Ala Ile Leu Met Gly Asp Lys 
    370                 375                 380                 


Ser Glu Asn Val Gln Asp Leu Leu Leu Leu Asp Val Ala Pro Leu Ser 
385                 390                 395                 400 


Leu Gly Leu Glu Thr Ala Gly Gly Val Met Thr Ala Leu Ile Lys Arg 
                405                 410                 415     


Asn Ser Thr Ile Pro Thr Lys Gln Thr Gln Ile Phe Thr Thr Tyr Ser 
            420                 425                 430         


Asp Asn Gln Pro Gly Val Leu Ile Gln Val Tyr Glu Gly Glu Arg Ala 
        435                 440                 445             


Met Thr Lys Asp Asn Asn Leu Leu Gly Arg Phe Glu Leu Ser Gly Ile 
    450                 455                 460                 


Pro Pro Ala Pro Arg Gly Val Pro Gln Ile Glu Val Thr Phe Asp Ile 
465                 470                 475                 480 


Asp Ala Asn Gly Ile Leu Asn Val Thr Ala Thr Asp Lys Ser Thr Gly 
                485                 490                 495     


Lys Ala Asn Lys Ile Thr Ile Thr Asn Asp Lys Gly Arg Leu Ser Lys 
            500                 505                 510         


Glu Glu Ile Glu Arg Met Val Gln Glu Ala Glu Lys Tyr Lys Ala Glu 
        515                 520                 525             


Asp Glu Val Gln Arg Glu Arg Val Ser Ala Lys Asn Ala Leu Glu Ser 
    530                 535                 540                 


Tyr Ala Phe Asn Met Lys Ser Ala Val Glu Asp Glu Gly Leu Lys Gly 
545                 550                 555                 560 


Lys Ile Ser Glu Ala Asp Lys Lys Lys Val Leu Asp Lys Cys Gln Glu 
                565                 570                 575     


Val Ile Ser Trp Leu Asp Ala Asn Thr Leu Ala Glu Lys Asp Glu Phe 
            580                 585                 590         


Glu His Lys Arg Lys Glu Leu Glu Gln Val Cys Asn Pro Ile Ile Ser 
        595                 600                 605             


Gly Leu Tyr Gln Gly Ala Gly Gly Pro Gly Pro Gly Gly Phe Gly Ala 
    610                 615                 620                 


Gln Gly Pro Lys Gly Gly Ser Gly Ser Gly Pro Thr Ile Glu Glu Val 
625                 630                 635                 640 


Asp 
    


<210>  1337
<211>  205
<212>  PRT
<213>  Human

<400>  1337

Met Thr Glu Arg Arg Val Pro Phe Ser Leu Leu Arg Gly Pro Ser Trp 
1               5                   10                  15      


Asp Pro Phe Arg Asp Trp Tyr Pro His Ser Arg Leu Phe Asp Gln Ala 
            20                  25                  30          


Phe Gly Leu Pro Arg Leu Pro Glu Glu Trp Ser Gln Trp Leu Gly Gly 
        35                  40                  45              


Ser Ser Trp Pro Gly Tyr Val Arg Pro Leu Pro Pro Ala Ala Ile Glu 
    50                  55                  60                  


Ser Pro Ala Val Ala Ala Pro Ala Tyr Ser Arg Ala Leu Ser Arg Gln 
65                  70                  75                  80  


Leu Ser Ser Gly Val Ser Glu Ile Arg His Thr Ala Asp Arg Trp Arg 
                85                  90                  95      


Val Ser Leu Asp Val Asn His Phe Ala Pro Asp Glu Leu Thr Val Lys 
            100                 105                 110         


Thr Lys Asp Gly Val Val Glu Ile Thr Gly Lys His Glu Glu Arg Gln 
        115                 120                 125             


Asp Glu His Gly Tyr Ile Ser Arg Cys Phe Thr Arg Lys Tyr Thr Leu 
    130                 135                 140                 


Pro Pro Gly Val Asp Pro Thr Gln Val Ser Ser Ser Leu Ser Pro Glu 
145                 150                 155                 160 


Gly Thr Leu Thr Val Glu Ala Pro Met Pro Lys Leu Ala Thr Gln Ser 
                165                 170                 175     


Asn Glu Ile Thr Ile Pro Val Thr Phe Glu Ser Arg Ala Gln Leu Gly 
            180                 185                 190         


Gly Pro Glu Ala Ala Lys Ser Asp Glu Thr Ala Ala Lys 
        195                 200                 205 


<210>  1338
<211>  480
<212>  PRT
<213>  Human

<400>  1338

Met Gln Ile Pro Arg Ala Ala Leu Leu Pro Leu Leu Leu Leu Leu Leu 
1               5                   10                  15      


Ala Ala Pro Ala Ser Ala Gln Leu Ser Arg Ala Gly Arg Ser Ala Pro 
            20                  25                  30          


Leu Ala Ala Gly Cys Pro Asp Arg Cys Glu Pro Ala Arg Cys Pro Pro 
        35                  40                  45              


Gln Pro Glu His Cys Glu Gly Gly Arg Ala Arg Asp Ala Cys Gly Cys 
    50                  55                  60                  


Cys Glu Val Cys Gly Ala Pro Glu Gly Ala Ala Cys Gly Leu Gln Glu 
65                  70                  75                  80  


Gly Pro Cys Gly Glu Gly Leu Gln Cys Val Val Pro Phe Gly Val Pro 
                85                  90                  95      


Ala Ser Ala Thr Val Arg Arg Arg Ala Gln Ala Gly Leu Cys Val Cys 
            100                 105                 110         


Ala Ser Ser Glu Pro Val Cys Gly Ser Asp Ala Asn Thr Tyr Ala Asn 
        115                 120                 125             


Leu Cys Gln Leu Arg Ala Ala Ser Arg Arg Ser Glu Arg Leu His Arg 
    130                 135                 140                 


Pro Pro Val Ile Val Leu Gln Arg Gly Ala Cys Gly Gln Gly Gln Glu 
145                 150                 155                 160 


Asp Pro Asn Ser Leu Arg His Lys Tyr Asn Phe Ile Ala Asp Val Val 
                165                 170                 175     


Glu Lys Ile Ala Pro Ala Val Val His Ile Glu Leu Phe Arg Lys Leu 
            180                 185                 190         


Pro Phe Ser Lys Arg Glu Val Pro Val Ala Ser Gly Ser Gly Phe Ile 
        195                 200                 205             


Val Ser Glu Asp Gly Leu Ile Val Thr Asn Ala His Val Val Thr Asn 
    210                 215                 220                 


Lys His Arg Val Lys Val Glu Leu Lys Asn Gly Ala Thr Tyr Glu Ala 
225                 230                 235                 240 


Lys Ile Lys Asp Val Asp Glu Lys Ala Asp Ile Ala Leu Ile Lys Ile 
                245                 250                 255     


Asp His Gln Gly Lys Leu Pro Val Leu Leu Leu Gly Arg Ser Ser Glu 
            260                 265                 270         


Leu Arg Pro Gly Glu Phe Val Val Ala Ile Gly Ser Pro Phe Ser Leu 
        275                 280                 285             


Gln Asn Thr Val Thr Thr Gly Ile Val Ser Thr Thr Gln Arg Gly Gly 
    290                 295                 300                 


Lys Glu Leu Gly Leu Arg Asn Ser Asp Met Asp Tyr Ile Gln Thr Asp 
305                 310                 315                 320 


Ala Ile Ile Asn Tyr Gly Asn Ser Gly Gly Pro Leu Val Asn Leu Asp 
                325                 330                 335     


Gly Glu Val Ile Gly Ile Asn Thr Leu Lys Val Thr Ala Gly Ile Ser 
            340                 345                 350         


Phe Ala Ile Pro Ser Asp Lys Ile Lys Lys Phe Leu Thr Glu Ser His 
        355                 360                 365             


Asp Arg Gln Ala Lys Gly Lys Ala Ile Thr Lys Lys Lys Tyr Ile Gly 
    370                 375                 380                 


Ile Arg Met Met Ser Leu Thr Ser Ser Lys Ala Lys Glu Leu Lys Asp 
385                 390                 395                 400 


Arg His Arg Asp Phe Pro Asp Val Ile Ser Gly Ala Tyr Ile Ile Glu 
                405                 410                 415     


Val Ile Pro Asp Thr Pro Ala Glu Ala Gly Gly Leu Lys Glu Asn Asp 
            420                 425                 430         


Val Ile Ile Ser Ile Asn Gly Gln Ser Val Val Ser Ala Asn Asp Val 
        435                 440                 445             


Ser Asp Val Ile Lys Arg Glu Ser Thr Leu Asn Met Val Val Arg Arg 
    450                 455                 460                 


Gly Asn Glu Asp Ile Met Ile Thr Val Ile Pro Glu Glu Ile Asp Pro 
465                 470                 475                 480 


<210>  1339
<211>  483
<212>  PRT
<213>  Human

<400>  1339

Met Ser Gly His Lys Cys Ser Tyr Pro Trp Asp Leu Gln Asp Arg Tyr 
1               5                   10                  15      


Ala Gln Asp Lys Ser Val Val Asn Lys Met Gln Gln Lys Tyr Trp Glu 
            20                  25                  30          


Thr Lys Gln Ala Phe Ile Lys Ala Thr Gly Lys Lys Glu Asp Glu His 
        35                  40                  45              


Val Val Ala Ser Asp Ala Asp Leu Asp Ala Lys Leu Glu Leu Phe His 
    50                  55                  60                  


Ser Ile Gln Arg Thr Cys Leu Asp Leu Ser Lys Ala Ile Val Leu Tyr 
65                  70                  75                  80  


Gln Lys Arg Ile Cys Phe Leu Ser Gln Glu Glu Asn Glu Leu Gly Lys 
                85                  90                  95      


Phe Leu Arg Ser Gln Gly Phe Gln Asp Lys Thr Arg Ala Gly Lys Met 
            100                 105                 110         


Met Gln Ala Thr Gly Lys Ala Leu Cys Phe Ser Ser Gln Gln Arg Leu 
        115                 120                 125             


Ala Leu Arg Asn Pro Leu Cys Arg Phe His Gln Glu Val Glu Thr Phe 
    130                 135                 140                 


Arg His Arg Ala Ile Ser Asp Thr Trp Leu Thr Val Asn Arg Met Glu 
145                 150                 155                 160 


Gln Cys Arg Thr Glu Tyr Arg Gly Ala Leu Leu Trp Met Lys Asp Val 
                165                 170                 175     


Ser Gln Glu Leu Asp Pro Asp Leu Tyr Lys Gln Met Glu Lys Phe Arg 
            180                 185                 190         


Lys Val Gln Thr Gln Val Arg Leu Ala Lys Lys Asn Phe Asp Lys Leu 
        195                 200                 205             


Lys Met Asp Val Cys Gln Lys Val Asp Leu Leu Gly Ala Ser Arg Cys 
    210                 215                 220                 


Asn Leu Leu Ser His Met Leu Ala Thr Tyr Gln Thr Thr Leu Leu His 
225                 230                 235                 240 


Phe Trp Glu Lys Thr Ser His Thr Met Ala Ala Ile His Glu Ser Phe 
                245                 250                 255     


Lys Gly Tyr Gln Pro Tyr Glu Phe Thr Thr Leu Lys Ser Leu Gln Asp 
            260                 265                 270         


Pro Met Lys Lys Leu Val Glu Lys Glu Glu Lys Lys Lys Ile Asn Gln 
        275                 280                 285             


Gln Glu Ser Thr Asp Ala Ala Val Gln Glu Pro Ser Gln Leu Ile Ser 
    290                 295                 300                 


Leu Glu Glu Glu Asn Gln Arg Lys Glu Ser Ser Ser Phe Lys Thr Glu 
305                 310                 315                 320 


Asp Gly Lys Ser Ile Leu Ser Ala Leu Asp Lys Gly Ser Thr His Thr 
                325                 330                 335     


Ala Cys Ser Gly Pro Ile Asp Glu Leu Leu Asp Met Lys Ser Glu Glu 
            340                 345                 350         


Gly Ala Cys Leu Gly Pro Val Ala Gly Thr Pro Glu Pro Glu Gly Ala 
        355                 360                 365             


Asp Lys Asp Asp Leu Leu Leu Leu Ser Glu Ile Phe Asn Ala Ser Ser 
    370                 375                 380                 


Leu Glu Glu Gly Glu Phe Ser Lys Glu Trp Ala Ala Val Phe Gly Asp 
385                 390                 395                 400 


Gly Gln Val Lys Glu Pro Val Pro Thr Met Ala Leu Gly Glu Pro Asp 
                405                 410                 415     


Pro Lys Ala Gln Thr Gly Ser Gly Phe Leu Pro Ser Gln Leu Leu Asp 
            420                 425                 430         


Gln Asn Met Lys Asp Leu Gln Ala Ser Leu Gln Glu Pro Ala Lys Ala 
        435                 440                 445             


Ala Ser Asp Leu Thr Ala Trp Phe Ser Leu Phe Ala Asp Leu Asp Pro 
    450                 455                 460                 


Leu Ser Asn Pro Asp Ala Val Gly Lys Thr Asp Lys Glu His Glu Leu 
465                 470                 475                 480 


Leu Asn Ala 
            


<210>  1340
<211>  557
<212>  PRT
<213>  Human

<400>  1340

Met Pro Glu Arg Asp Ser Glu Pro Phe Ser Asn Pro Leu Ala Pro Asp 
1               5                   10                  15      


Gly His Asp Val Asp Asp Pro His Ser Phe His Gln Ser Lys Leu Thr 
            20                  25                  30          


Asn Glu Asp Phe Arg Lys Leu Leu Met Thr Pro Arg Ala Ala Pro Thr 
        35                  40                  45              


Ser Ala Pro Pro Ser Lys Ser Arg His His Glu Met Pro Arg Glu Tyr 
    50                  55                  60                  


Asn Glu Asp Glu Asp Pro Ala Ala Arg Arg Arg Lys Lys Lys Ser Tyr 
65                  70                  75                  80  


Tyr Ala Lys Leu Arg Gln Gln Glu Ile Glu Arg Glu Arg Glu Leu Ala 
                85                  90                  95      


Glu Lys Tyr Arg Asp Arg Ala Lys Glu Arg Arg Asp Gly Val Asn Lys 
            100                 105                 110         


Asp Tyr Glu Glu Thr Glu Leu Ile Ser Thr Thr Ala Asn Tyr Arg Ala 
        115                 120                 125             


Val Gly Pro Thr Ala Glu Ala Asp Lys Ser Ala Ala Glu Lys Arg Arg 
    130                 135                 140                 


Gln Leu Ile Gln Glu Ser Lys Phe Leu Gly Gly Asp Met Glu His Thr 
145                 150                 155                 160 


His Leu Val Lys Gly Leu Asp Phe Ala Leu Leu Gln Lys Val Arg Ala 
                165                 170                 175     


Glu Ile Ala Ser Lys Glu Lys Glu Glu Glu Glu Leu Met Glu Lys Pro 
            180                 185                 190         


Gln Lys Glu Thr Lys Lys Asp Glu Asp Pro Glu Asn Lys Ile Glu Phe 
        195                 200                 205             


Lys Thr Arg Leu Gly Arg Asn Val Tyr Arg Met Leu Phe Lys Ser Lys 
    210                 215                 220                 


Ala Tyr Glu Arg Asn Glu Leu Phe Leu Pro Gly Arg Met Ala Tyr Val 
225                 230                 235                 240 


Val Asp Leu Asp Asp Glu Tyr Ala Asp Thr Asp Ile Pro Thr Thr Leu 
                245                 250                 255     


Ile Arg Ser Lys Ala Asp Cys Pro Thr Met Glu Ala Gln Thr Thr Leu 
            260                 265                 270         


Thr Thr Asn Asp Ile Val Ile Ser Lys Leu Thr Gln Ile Leu Ser Tyr 
        275                 280                 285             


Leu Arg Gln Gly Thr Arg Asn Lys Lys Leu Lys Lys Lys Asp Lys Gly 
    290                 295                 300                 


Lys Leu Glu Glu Lys Lys Pro Pro Glu Ala Asp Met Asn Ile Phe Glu 
305                 310                 315                 320 


Asp Ile Gly Asp Tyr Val Pro Ser Thr Thr Lys Thr Pro Arg Asp Lys 
                325                 330                 335     


Glu Arg Glu Arg Tyr Arg Glu Arg Glu Arg Asp Arg Glu Arg Asp Arg 
            340                 345                 350         


Asp Arg Asp Arg Glu Arg Glu Arg Glu Arg Asp Arg Glu Arg Glu Arg 
        355                 360                 365             


Glu Arg Asp Arg Glu Arg Glu Glu Glu Lys Lys Arg His Ser Tyr Phe 
    370                 375                 380                 


Glu Lys Pro Lys Val Asp Asp Glu Pro Met Asp Val Asp Lys Gly Pro 
385                 390                 395                 400 


Gly Ser Thr Lys Glu Leu Ile Lys Ser Ile Asn Glu Lys Phe Ala Gly 
                405                 410                 415     


Ser Ala Gly Trp Glu Gly Thr Glu Ser Leu Lys Lys Pro Glu Asp Lys 
            420                 425                 430         


Lys Gln Leu Gly Asp Phe Phe Gly Met Ser Asn Ser Tyr Ala Glu Cys 
        435                 440                 445             


Tyr Pro Ala Thr Met Asp Asp Met Ala Val Asp Ser Asp Glu Glu Val 
    450                 455                 460                 


Asp Tyr Ser Lys Met Asp Gln Gly Asn Lys Lys Gly Pro Leu Gly Arg 
465                 470                 475                 480 


Trp Asp Phe Asp Thr Gln Glu Glu Tyr Ser Glu Tyr Met Asn Asn Lys 
                485                 490                 495     


Glu Ala Leu Pro Lys Ala Ala Phe Gln Tyr Gly Ile Lys Met Ser Glu 
            500                 505                 510         


Gly Arg Lys Thr Arg Arg Phe Lys Glu Thr Asn Asp Lys Ala Glu Leu 
        515                 520                 525             


Asp Arg Gln Trp Lys Lys Ile Ser Ala Ile Ile Glu Lys Arg Lys Lys 
    530                 535                 540                 


Met Glu Ala Asp Gly Val Glu Val Lys Arg Pro Lys Tyr 
545                 550                 555         


<210>  1341
<211>  392
<212>  PRT
<213>  Human

<400>  1341

Met Asp Leu Phe Gly Asp Leu Pro Glu Pro Glu Arg Ser Pro Arg Pro 
1               5                   10                  15      


Ala Ala Gly Lys Glu Ala Gln Lys Gly Pro Leu Leu Phe Asp Asp Leu 
            20                  25                  30          


Pro Pro Ala Ser Ser Thr Asp Ser Gly Ser Gly Gly Pro Leu Leu Phe 
        35                  40                  45              


Asp Asp Leu Pro Pro Ala Ser Ser Gly Asp Ser Gly Ser Leu Ala Thr 
    50                  55                  60                  


Ser Ile Ser Gln Met Val Lys Thr Glu Gly Lys Gly Ala Lys Arg Lys 
65                  70                  75                  80  


Thr Ser Glu Glu Glu Lys Asn Gly Ser Glu Glu Leu Val Glu Lys Lys 
                85                  90                  95      


Val Cys Lys Ala Ser Ser Val Ile Phe Gly Leu Lys Gly Tyr Val Ala 
            100                 105                 110         


Glu Arg Lys Gly Glu Arg Glu Glu Met Gln Asp Ala His Val Ile Leu 
        115                 120                 125             


Asn Asp Ile Thr Glu Glu Cys Arg Pro Pro Ser Ser Leu Ile Thr Arg 
    130                 135                 140                 


Val Ser Tyr Phe Ala Val Phe Asp Gly His Gly Gly Ile Arg Ala Ser 
145                 150                 155                 160 


Lys Phe Ala Ala Gln Asn Leu His Gln Asn Leu Ile Arg Lys Phe Pro 
                165                 170                 175     


Lys Gly Asp Val Ile Ser Val Glu Lys Thr Val Lys Arg Cys Leu Leu 
            180                 185                 190         


Asp Thr Phe Lys His Thr Asp Glu Glu Phe Leu Lys Gln Ala Ser Ser 
        195                 200                 205             


Gln Lys Pro Ala Trp Lys Asp Gly Ser Thr Ala Thr Cys Val Leu Ala 
    210                 215                 220                 


Val Asp Asn Ile Leu Tyr Ile Ala Asn Leu Gly Asp Ser Arg Ala Ile 
225                 230                 235                 240 


Leu Cys Arg Tyr Asn Glu Glu Ser Gln Lys His Ala Ala Leu Ser Leu 
                245                 250                 255     


Ser Lys Glu His Asn Pro Thr Gln Tyr Glu Glu Arg Met Arg Ile Gln 
            260                 265                 270         


Lys Ala Gly Gly Asn Val Arg Asp Gly Arg Val Leu Gly Val Leu Glu 
        275                 280                 285             


Val Ser Arg Ser Ile Gly Asp Gly Gln Tyr Lys Arg Cys Gly Val Thr 
    290                 295                 300                 


Ser Val Pro Asp Ile Arg Arg Cys Gln Leu Thr Pro Asn Asp Arg Phe 
305                 310                 315                 320 


Ile Leu Leu Ala Cys Asp Gly Leu Phe Lys Val Phe Thr Pro Glu Glu 
                325                 330                 335     


Ala Val Asn Phe Ile Leu Ser Cys Leu Glu Asp Glu Lys Ile Gln Thr 
            340                 345                 350         


Arg Glu Gly Lys Ser Ala Ala Asp Ala Arg Tyr Glu Ala Ala Cys Asn 
        355                 360                 365             


Arg Leu Ala Asn Lys Ala Val Gln Arg Gly Ser Ala Asp Asn Val Thr 
    370                 375                 380                 


Val Met Val Val Arg Ile Gly His 
385                 390         


<210>  1342
<211>  5005
<212>  PRT
<213>  Human

<400>  1342

Met Asp Gln Arg Lys Asn Glu Ser Ile Val Pro Ser Ile Thr Gln Leu 
1               5                   10                  15      


Glu Asp Phe Leu Thr Glu His Asn Ser Asn Val Val Trp Leu Leu Val 
            20                  25                  30          


Ala Thr Ile Leu Ser Cys Gly Trp Ile Ile Tyr Leu Thr Tyr Tyr Asn 
        35                  40                  45              


Ser Arg Asn Val Gly Leu Ile Leu Thr Leu Val Leu Asn Arg Leu Tyr 
    50                  55                  60                  


Lys His Gly Tyr Ile His Ile Gly Ser Phe Ser Phe Ser Val Leu Ser 
65                  70                  75                  80  


Gly Lys Val Met Val Arg Glu Ile Tyr Tyr Ile Thr Glu Asp Met Ser 
                85                  90                  95      


Ile Arg Ile Gln Asp Gly Phe Ile Ile Phe Arg Trp Trp Lys Met Tyr 
            100                 105                 110         


Asn Pro Lys Gln Lys Gln His Asp Pro Lys Ala Glu Thr Arg Leu Tyr 
        115                 120                 125             


Ile Thr Val Asn Asp Phe Glu Phe His Val Tyr Asn Arg Ser Asp Leu 
    130                 135                 140                 


Tyr Gly Arg Leu Gln Glu Leu Phe Gly Leu Glu Pro Thr Ile Ile Pro 
145                 150                 155                 160 


Pro Lys Lys Asp Asp Asp Lys Thr Arg Glu Ile Gly Arg Thr Arg Thr 
                165                 170                 175     


Gln Ser Lys Ile Glu Arg Val Lys Val Lys Thr Glu Ser Gln Asp Pro 
            180                 185                 190         


Thr Ser Ser Trp Arg Ser Leu Ile Pro Val Ile Lys Val Asn Val Ser 
        195                 200                 205             


Thr Gly Arg Leu Ala Phe Gly Asn His Tyr Gln Pro Gln Thr Leu Cys 
    210                 215                 220                 


Ile Asn Phe Asp Asp Ala Phe Leu Thr Tyr Thr Thr Lys Pro Pro Ser 
225                 230                 235                 240 


Ser His Leu Asp Gln Phe Met His Ile Val Lys Gly Lys Leu Glu Asn 
                245                 250                 255     


Val Arg Val Met Leu Val Pro Ser Pro Arg Tyr Val Gly Leu Gln Asn 
            260                 265                 270         


Asp Glu Pro Pro Arg Leu Met Gly Glu Gly Phe Val Val Met Gln Ser 
        275                 280                 285             


Asn Asp Val Asp Ile Tyr Tyr Tyr Met Asp Glu Pro Gly Leu Val Pro 
    290                 295                 300                 


Glu Glu Thr Glu Glu Asn Ile Glu Gly Glu Met Ser Ser Glu Asp Cys 
305                 310                 315                 320 


Lys Leu Gln Asp Leu Pro Pro Cys Trp Gly Leu Asp Ile Val Cys Gly 
                325                 330                 335     


Lys Gly Thr Asp Phe Asn Tyr Gly Pro Trp Ala Asp Arg Gln Arg Asp 
            340                 345                 350         


Cys Leu Trp Lys Phe Phe Phe Pro Pro Asp Tyr Gln Val Leu Lys Val 
        355                 360                 365             


Ser Glu Ile Ala Gln Pro Gly Arg Pro Arg Gln Ile Leu Ala Phe Glu 
    370                 375                 380                 


Leu Arg Met Asn Ile Ile Ala Asp Ala Thr Ile Asp Leu Leu Phe Thr 
385                 390                 395                 400 


Lys Asn Arg Glu Thr Asn Ala Val His Val Asn Val Gly Ala Gly Ser 
                405                 410                 415     


Tyr Leu Glu Ile Asn Ile Pro Met Thr Val Glu Glu Asn Gly Tyr Thr 
            420                 425                 430         


Pro Ala Ile Lys Gly Gln Leu Leu His Val Asp Ala Thr Thr Ser Met 
        435                 440                 445             


Gln Tyr Arg Thr Leu Leu Glu Ala Glu Met Leu Ala Phe His Ile Asn 
    450                 455                 460                 


Ala Ser Tyr Pro Arg Ile Trp Asn Met Pro Gln Thr Trp Gln Cys Glu 
465                 470                 475                 480 


Leu Glu Val Tyr Lys Ala Thr Tyr His Phe Ile Phe Ala Gln Lys Asn 
                485                 490                 495     


Phe Phe Thr Asp Leu Ile Gln Asp Trp Ser Ser Asp Ser Pro Pro Asp 
            500                 505                 510         


Ile Phe Ser Phe Val Pro Tyr Thr Trp Asn Phe Lys Ile Met Phe His 
        515                 520                 525             


Gln Phe Glu Met Ile Trp Ala Ala Asn Gln His Asn Trp Ile Asp Cys 
    530                 535                 540                 


Ser Thr Lys Gln Gln Glu Asn Val Tyr Leu Ala Ala Cys Gly Glu Thr 
545                 550                 555                 560 


Leu Asn Ile Asp Phe Ser Leu Pro Phe Thr Asp Phe Val Pro Ala Thr 
                565                 570                 575     


Cys Asn Thr Lys Phe Ser Leu Arg Gly Glu Asp Val Asp Leu His Leu 
            580                 585                 590         


Phe Leu Pro Asp Cys His Pro Ser Lys Tyr Ser Leu Phe Met Leu Val 
        595                 600                 605             


Lys Asn Cys His Pro Asn Lys Met Ile His Asp Thr Gly Ile Pro Ala 
    610                 615                 620                 


Glu Cys Gln Ser Gly Gln Lys Thr Val Lys Pro Lys Trp Arg Asn Val 
625                 630                 635                 640 


Thr Gln Glu Lys Ser Gly Trp Val Glu Cys Trp Thr Val Pro Ser Val 
                645                 650                 655     


Met Leu Thr Ile Asp Tyr Thr Trp His Pro Ile Tyr Pro Gln Lys Ala 
            660                 665                 670         


Asp Glu Gln Leu Lys Gln Ser Leu Ser Glu Met Glu Glu Thr Met Leu 
        675                 680                 685             


Ser Val Leu Arg Pro Ser Gln Lys Thr Ser Asp Arg Val Val Ser Ser 
    690                 695                 700                 


Pro Ser Thr Ser Ser Arg Pro Pro Ile Asp Pro Ser Glu Leu Pro Pro 
705                 710                 715                 720 


Asp Lys Leu His Val Glu Met Glu Leu Ser Pro Asp Ser Gln Ile Thr 
                725                 730                 735     


Leu Tyr Gly Pro Leu Leu Asn Ala Phe Leu Cys Ile Lys Glu Asn Tyr 
            740                 745                 750         


Phe Gly Glu Asp Asp Met Tyr Met Asp Phe Glu Glu Val Ile Ser Ser 
        755                 760                 765             


Pro Val Leu Ser Leu Ser Thr Ser Ser Ser Ser Gly Trp Thr Ala Val 
    770                 775                 780                 


Gly Met Glu Asn Asp Lys Lys Glu Asn Glu Gly Ser Ala Lys Ser Ile 
785                 790                 795                 800 


His Pro Leu Ala Leu Arg Pro Trp Asp Ile Thr Val Leu Val Asn Leu 
                805                 810                 815     


Tyr Lys Val His Gly Arg Leu Pro Val His Gly Thr Thr Asp Gly Pro 
            820                 825                 830         


Glu Cys Pro Thr Ala Phe Leu Glu Arg Leu Cys Phe Glu Met Lys Lys 
        835                 840                 845             


Gly Phe Arg Glu Thr Met Leu Gln Leu Ile Leu Ser Pro Leu Asn Val 
    850                 855                 860                 


Phe Val Ser Asp Asn Tyr Gln Gln Arg Pro Pro Val Asp Glu Val Leu 
865                 870                 875                 880 


Arg Glu Gly His Ile Asn Leu Ser Gly Leu Gln Leu Arg Ala His Ala 
                885                 890                 895     


Met Phe Ser Ala Glu Gly Leu Pro Leu Gly Ser Asp Ser Leu Glu Tyr 
            900                 905                 910         


Ala Trp Leu Ile Asp Val Gln Ala Gly Ser Leu Thr Ala Lys Val Thr 
        915                 920                 925             


Ala Pro Gln Leu Ala Cys Leu Leu Glu Trp Gly Gln Thr Phe Val Phe 
    930                 935                 940                 


His Val Val Cys Arg Glu Tyr Glu Leu Glu Arg Pro Lys Ser Val Ile 
945                 950                 955                 960 


Ile Cys Gln His Gly Ile Asp Arg Arg Phe Cys Glu Ser Lys Leu Ser 
                965                 970                 975     


Cys Ile Pro Gly Pro Cys Pro Thr Ser Asp Asp Leu Lys Tyr Thr Met 
            980                 985                 990         


Ile Arg Leu Ala Val Asp Gly Ala  Asp Ile Tyr Ile Val  Glu His Gly 
        995                 1000                 1005             


Cys Ala  Thr Asn Ile Lys Met  Gly Ala Ile Arg Val  Ala Asn Cys 
    1010                 1015                 1020             


Asn Leu  His Asn Gln Ser Val  Gly Glu Gly Ile Ser  Ala Ala Ile 
    1025                 1030                 1035             


Gln Asp  Phe Gln Val Arg Gln  Tyr Ile Glu Gln Leu  Asn Asn Cys 
    1040                 1045                 1050             


Arg Ile  Gly Leu Gln Pro Ala  Val Leu Arg Arg Ala  Tyr Trp Leu 
    1055                 1060                 1065             


Glu Ala  Gly Ser Ala Asn Leu  Gly Leu Ile Thr Val  Asp Ile Ala 
    1070                 1075                 1080             


Leu Ala  Ala Asp His His Ser  Lys His Glu Ala Gln  Arg His Phe 
    1085                 1090                 1095             


Leu Glu  Thr His Asp Ala Arg  Thr Lys Arg Leu Trp  Phe Leu Trp 
    1100                 1105                 1110             


Pro Asp  Asp Ile Leu Lys Asn  Lys Arg Cys Arg Asn  Lys Cys Gly 
    1115                 1120                 1125             


Cys Leu  Gly Gly Cys Arg Phe  Phe Gly Gly Thr Val  Thr Gly Leu 
    1130                 1135                 1140             


Asp Phe  Phe Lys Leu Glu Glu  Leu Thr Pro Ser Ser  Ser Ser Ala 
    1145                 1150                 1155             


Phe Ser  Ser Thr Ser Ala Glu  Ser Asp Met Tyr Tyr  Gly Gln Ser 
    1160                 1165                 1170             


Leu Leu  Gln Pro Gly Glu Trp  Ile Ile Thr Lys Glu  Ile Pro Lys 
    1175                 1180                 1185             


Ile Ile  Asp Gly Asn Val Asn  Gly Met Lys Arg Lys  Glu Trp Glu 
    1190                 1195                 1200             


Asn Lys  Ser Val Gly Ile Glu  Val Glu Arg Lys Thr  Gln His Leu 
    1205                 1210                 1215             


Ser Leu  Gln Val Pro Leu Arg  Ser His Ser Ser Ser  Ser Ser Ser 
    1220                 1225                 1230             


Glu Glu  Asn Ser Ser Ser Ser  Ala Ala Gln Pro Leu  Leu Ala Gly 
    1235                 1240                 1245             


Glu Lys  Glu Ser Pro Ser Ser  Val Ala Asp Asp His  Leu Val Gln 
    1250                 1255                 1260             


Lys Glu  Phe Leu His Gly Thr  Lys Arg Asp Asp Gly  Gln Ala Ser 
    1265                 1270                 1275             


Ile Pro  Thr Glu Ile Ser Gly  Asn Ser Pro Val Ser  Pro Asn Thr 
    1280                 1285                 1290             


Gln Asp  Lys Ser Val Gly Gln  Ser Pro Leu Arg Ser  Pro Leu Lys 
    1295                 1300                 1305             


Arg Gln  Ala Ser Val Cys Ser  Thr Arg Leu Gly Ser  Thr Lys Ser 
    1310                 1315                 1320             


Leu Thr  Ala Ala Phe Tyr Gly  Asp Lys Gln Pro Val  Thr Val Gly 
    1325                 1330                 1335             


Val Gln  Phe Ser Ser Asp Val  Ser Arg Ser Asp Glu  Asn Val Leu 
    1340                 1345                 1350             


Asp Ser  Pro Lys Gln Arg Arg  Ser Phe Gly Ser Phe  Pro Tyr Thr 
    1355                 1360                 1365             


Pro Ser  Ala Asp Ser Asn Ser  Phe His Gln Tyr Arg  Ser Met Asp 
    1370                 1375                 1380             


Ser Ser  Met Ser Met Ala Asp  Ser Glu Ala Tyr Phe  Ser Ala Ala 
    1385                 1390                 1395             


Glu Glu  Phe Glu Pro Ile Ser  Ser Asp Glu Gly Pro  Gly Thr Tyr 
    1400                 1405                 1410             


Pro Gly  Arg Lys Lys Lys Lys  Lys Gln Thr Gln Gln  Ile Asp Tyr 
    1415                 1420                 1425             


Ser Arg  Gly Ser Ile Tyr His  Ser Val Glu Gly Pro  Leu Thr Gly 
    1430                 1435                 1440             


His Gly  Glu Ser Ile Gln Asp  Ser Arg Thr Leu Pro  Phe Lys Thr 
    1445                 1450                 1455             


His Pro  Ser Gln Ala Ser Phe  Val Ser Ala Leu Gly  Gly Glu Asp 
    1460                 1465                 1470             


Asp Val  Ile Glu His Leu Tyr  Ile Val Glu Gly Glu  Lys Thr Val 
    1475                 1480                 1485             


Glu Ser  Glu Gln Ile Thr Pro  Gln Gln Pro Val Met  Asn Cys Tyr 
    1490                 1495                 1500             


Gln Thr  Tyr Leu Thr Gln Phe  Gln Val Ile Asn Trp  Ser Val Lys 
    1505                 1510                 1515             


His Pro  Thr Asn Lys Arg Thr  Ser Lys Ser Ser Leu  His Arg Pro 
    1520                 1525                 1530             


Leu Asp  Leu Asp Thr Pro Thr  Ser Glu Glu Ser Ser  Ser Ser Phe 
    1535                 1540                 1545             


Glu Gln  Leu Ser Val Pro Thr  Phe Lys Val Ile Lys  Gln Gly Leu 
    1550                 1555                 1560             


Thr Ala  Asn Ser Leu Leu Asp  Arg Gly Met Gln Leu  Ser Gly Ser 
    1565                 1570                 1575             


Thr Ser  Asn Thr Pro Tyr Thr  Pro Leu Glu Lys Lys  Leu Ala Asp 
    1580                 1585                 1590             


Asn Thr  Asp Asp Glu Thr Leu  Thr Glu Glu Trp Thr  Leu Asp Gln 
    1595                 1600                 1605             


Pro Val  Ser Gln Thr Arg Thr  Thr Ala Ile Val Glu  Val Lys Gly 
    1610                 1615                 1620             


Thr Val  Asp Ile Val Leu Thr  Pro Leu Val Ala Glu  Ala Leu Asp 
    1625                 1630                 1635             


Arg Tyr  Ile Glu Ala Met Val  His Cys Ala Ser Thr  Arg His Pro 
    1640                 1645                 1650             


Ala Ala  Ile Val Asp Asp Leu  His Ala Lys Val Leu  Arg Glu Ala 
    1655                 1660                 1665             


Val Gln  Asn Ser Lys Thr Thr  Phe Ser Glu Asn Leu  Ser Ser Lys 
    1670                 1675                 1680             


Gln Asp  Ile Arg Gly Thr Lys  Thr Glu Gln Ser Thr  Ile Gly Thr 
    1685                 1690                 1695             


Thr Asn  Gln Gly Gln Ala Gln  Thr Asn Leu Thr Met  Lys Gln Asp 
    1700                 1705                 1710             


Asn Val  Thr Ile Lys Gly Leu  Gln Thr Asn Val Ser  Ile Pro Lys 
    1715                 1720                 1725             


Val Asn  Leu Cys Leu Leu Gln  Ala Ser Val Glu Glu  Ser Pro Thr 
    1730                 1735                 1740             


Thr Ala  Pro Ser Arg Ser Val  Thr His Val Ser Leu  Val Ala Leu 
    1745                 1750                 1755             


Cys Phe  Asp Arg Ile Ala Thr  Gln Val Arg Met Asn  Arg Gly Val 
    1760                 1765                 1770             


Val Glu  Glu Thr Ser Asn Asn  Ala Glu Pro Gly Arg  Thr Ser Asn 
    1775                 1780                 1785             


Phe Asp  Arg Tyr Val His Ala  Thr Lys Met Gln Pro  Gln Ser Ser 
    1790                 1795                 1800             


Gly Ser  Leu Arg Ser Asn Ala  Gly Ala Glu Lys Gly  Lys Glu Ile 
    1805                 1810                 1815             


Ala Ala  Lys Leu Asn Ile His  Arg Val His Gly Gln  Leu Arg Gly 
    1820                 1825                 1830             


Leu Asp  Thr Thr Asp Ile Gly  Thr Cys Ala Ile Thr  Ala Ile Pro 
    1835                 1840                 1845             


Phe Glu  Lys Ser Lys Val Leu  Phe Thr Leu Glu Glu  Leu Asp Glu 
    1850                 1855                 1860             


Phe Thr  Phe Val Asp Glu Thr  Asp Gln Gln Ala Val  Pro Asp Val 
    1865                 1870                 1875             


Thr Arg  Ile Gly Pro Ser Gln  Glu Lys Trp Gly Trp  Ile Met Phe 
    1880                 1885                 1890             


Glu Cys  Gly Leu Glu Asn Leu  Thr Ile Lys Gly Gly  Arg Gln Ser 
    1895                 1900                 1905             


Gly Ala  Val Leu Tyr Asn Ser  Phe Gly Ile Met Gly  Lys Ala Ser 
    1910                 1915                 1920             


Asp Thr  Glu Arg Gly Gly Val  Leu Thr Ser Asn Asn  Ser Ser Asp 
    1925                 1930                 1935             


Ser Pro  Thr Gly Ser Gly Tyr  Asn Thr Asp Val Ser  Asp Asp Asn 
    1940                 1945                 1950             


Leu Pro  Cys Asp Arg Thr Ser  Pro Ser Ser Asp Leu  Asn Gly Asn 
    1955                 1960                 1965             


Ser Val  Ser Asp Glu Gln Asp  Glu Gly Val Glu Ser  Asp Asp Leu 
    1970                 1975                 1980             


Lys Lys  Asp Leu Pro Leu Met  Pro Pro Pro Pro Asp  Ser Cys Ser 
    1985                 1990                 1995             


Met Lys  Leu Thr Ile Lys Glu  Ile Trp Phe Ser Phe  Ala Ala Pro 
    2000                 2005                 2010             


Thr Asn  Val Arg Ser His Thr  His Ala Phe Ser Arg  Gln Leu Asn 
    2015                 2020                 2025             


Leu Leu  Ser Thr Ala Thr Pro  Ala Val Gly Ala Trp  Leu Val Pro 
    2030                 2035                 2040             


Ile Asp  Gln Leu Lys Ser Ser  Leu Asn Lys Leu Glu  Thr Glu Gly 
    2045                 2050                 2055             


Thr Leu  Arg Ile Cys Ala Val  Met Gly Cys Ile Met  Thr Glu Ala 
    2060                 2065                 2070             


Leu Glu  Asn Lys Ser Val His  Phe Pro Leu Arg Ser  Lys Tyr Asn 
    2075                 2080                 2085             


Arg Leu  Thr Lys Val Ala Arg  Phe Leu Gln Glu Asn  Pro Ser Cys 
    2090                 2095                 2100             


Leu Leu  Cys Asn Ile Leu His  His Tyr Leu His Gln  Ala Asn Tyr 
    2105                 2110                 2115             


Ser Ile  Ile Asp Asp Ala Thr  Met Ser Asp Gly Leu  Pro Ala Leu 
    2120                 2125                 2130             


Val Thr  Leu Lys Lys Gly Leu  Val Ala Leu Ala Arg  Gln Trp Met 
    2135                 2140                 2145             


Lys Phe  Ile Val Val Thr Pro  Ala Phe Lys Gly Val  Ser Leu His 
    2150                 2155                 2160             


Arg Pro  Ala Gln Pro Leu Lys  Pro Gln Ile Ala Met  Asp His Glu 
    2165                 2170                 2175             


His Glu  Asp Gly Leu Gly Leu  Asp Asn Gly Gly Gly  Leu Gln Ser 
    2180                 2185                 2190             


Asp Thr  Ser Ala Asp Gly Ala  Glu Phe Glu Phe Asp  Ala Ala Thr 
    2195                 2200                 2205             


Val Ser  Glu His Thr Met Leu  Leu Glu Gly Thr Ala  Asn Arg Pro 
    2210                 2215                 2220             


Pro Pro  Gly Ser Ser Gly Pro  Val Thr Gly Ala Glu  Ile Met Arg 
    2225                 2230                 2235             


Lys Leu  Ser Lys Thr His Thr  His Ser Asp Ser Ala  Leu Lys Ile 
    2240                 2245                 2250             


Lys Gly  Ile His Pro Tyr His  Ser Leu Ser Tyr Thr  Ser Gly Asp 
    2255                 2260                 2265             


Thr Ala  Thr Asp Ser Pro Val  His Val Gly Arg Ala  Gly Met Pro 
    2270                 2275                 2280             


Val Lys  Asp Ser Pro Arg Lys  Glu Ser Leu Leu Ser  Tyr Leu Thr 
    2285                 2290                 2295             


Gly Ser  Phe Pro Ser Leu His  Asn Leu Leu Glu Gly  Thr Pro Gln 
    2300                 2305                 2310             


Arg Ser  Ser Ala Ala Val Lys  Ser Ser Ser Leu Thr  Arg Thr Gly 
    2315                 2320                 2325             


Asn Thr  Val Ala Thr Asp Met  Leu Ser Glu His Pro  Leu Leu Ser 
    2330                 2335                 2340             


Glu Pro  Ser Ser Val Ser Phe  Tyr Asn Trp Met Ser  Asn Ala Val 
    2345                 2350                 2355             


Gly Asn  Arg Gly Ser Val Leu  Gln Glu Ser Pro Val  Thr Lys Ser 
    2360                 2365                 2370             


Gly His  Asn Ser Leu Pro Thr  Gly Val Ala Pro Asn  Leu Pro Thr 
    2375                 2380                 2385             


Ile Pro  Ser Ala Ser Asp Phe  Asn Thr Val Leu Ser  Ser Asp Gln 
    2390                 2395                 2400             


Asn Thr  Leu Asp Gly Thr His  Ser Gln His Ser Thr  Ser Gln Asp 
    2405                 2410                 2415             


Asp Val  Ala Gly Val Glu Glu  Ala Asn Gln Gly Phe  Pro Ala Val 
    2420                 2425                 2430             


Gln Leu  Ala Asp Ala Gln Val  Val Phe Lys Pro Leu  Leu Ser His 
    2435                 2440                 2445             


Thr Gly  Ile Gln Ser Gln Asp  Thr Met Pro Phe Cys  Tyr Arg Met 
    2450                 2455                 2460             


Tyr Phe  Gly Glu His Leu Ser  Phe Ser Gly Thr Leu  Asp Cys Leu 
    2465                 2470                 2475             


Arg Ala  Asp Ile Val Asp Ser  Asp Thr Ala Lys Glu  Arg Lys Gly 
    2480                 2485                 2490             


Lys Arg  Ala Arg Arg Gln Gly  His Val Asn Leu Pro  Pro Leu Glu 
    2495                 2500                 2505             


Phe Lys  Pro Ala Leu Met Leu  Gly Thr Phe Ser Ile  Ser Ala Val 
    2510                 2515                 2520             


Val Met  Glu Lys Ser Val Cys  Thr Pro Gln Asn Ser  Thr Ser Ala 
    2525                 2530                 2535             


Leu Ser  Phe His Asp Leu Ser  Lys Arg Tyr Tyr Asn  Thr Phe His 
    2540                 2545                 2550             


Cys Asn  Phe Thr Ile Ser Cys  Gln Ser Ile Ser Gln  His Val Asp 
    2555                 2560                 2565             


Met Ala  Leu Val Arg Leu Ile  His Gln Phe Ser Thr  Met Ile Asp 
    2570                 2575                 2580             


Asp Ile  Lys Ala Thr Gln Thr  Asp Ile Lys Leu Ser  Arg Tyr Thr 
    2585                 2590                 2595             


Ala Gly  Ser Ala Ser Pro Thr  Pro Thr Phe Lys Thr  Arg Lys His 
    2600                 2605                 2610             


Arg Asp  Phe Arg Ser Ser Asp  Phe Ser Arg Ser Ser  Arg Gly Ser 
    2615                 2620                 2625             


Leu Asn  Gly Gly Asn Arg Val  Asn Asn Ala Lys Asn  Lys Arg Thr 
    2630                 2635                 2640             


Asn Asn  Glu Asn Asn Lys Lys  Glu Ser Arg Asn Lys  Asn Ser Leu 
    2645                 2650                 2655             


Gly Arg  Ser Glu Arg Arg Thr  Ser Lys Val Ser Arg  Lys Gly Ser 
    2660                 2665                 2670             


Lys Asp  Val Val Asp His Met  Thr Ile His Met Asp  Asp Ser Asp 
    2675                 2680                 2685             


Ser Ile  Thr Val Ser Glu Gln  Ser Glu Pro Ser Ala  Glu Cys Trp 
    2690                 2695                 2700             


Gln Asn  Met Tyr Lys Leu Leu  Asn Phe Tyr Ser Leu  Ile Ser Asp 
    2705                 2710                 2715             


Pro Thr  Gly Ile Leu Glu Lys  Ser Ser Glu Thr Phe  Gly Pro Ala 
    2720                 2725                 2730             


Gly Val  Arg Ser Pro Thr Glu  Pro Thr Cys Lys Val  Val Phe Glu 
    2735                 2740                 2745             


Asn Glu  Gln Asp Asn Ser Ser  Leu Thr Lys Thr Gln  Arg Lys Arg 
    2750                 2755                 2760             


Ser Leu  Val Thr Ser Glu Pro  Gln His Val Thr Leu  Ile Val Phe 
    2765                 2770                 2775             


Gly Ile  Gly Met Val Asn Arg  Thr His Leu Glu Ala  Asp Ile Gly 
    2780                 2785                 2790             


Gly Leu  Thr Met Glu Ser Glu  Leu Lys Arg Ile His  Gly Ser Phe 
    2795                 2800                 2805             


Thr Leu  Lys Glu Lys Met Lys  Asp Val Leu His Gln  Lys Met Thr 
    2810                 2815                 2820             


Glu Thr  Cys Ala Thr Ala His  Ile Gly Gly Val Asn  Ile Val Leu 
    2825                 2830                 2835             


Leu Glu  Gly Ile Thr Pro Asn  Ile Gln Leu Glu Asp  Phe Pro Thr 
    2840                 2845                 2850             


Ser Pro  Thr Ser Thr Ala Lys  Gln Glu Phe Leu Thr  Val Val Lys 
    2855                 2860                 2865             


Cys Ser  Ile Ala Lys Ser Gln  Ala Leu Tyr Ser Ala  Gln Arg Gly 
    2870                 2875                 2880             


Leu Lys  Thr Asn Asn Ala Ala  Val Phe Lys Val Gly  Ala Ile Ser 
    2885                 2890                 2895             


Ile Asn  Ile Pro Gln His Pro  Ala Thr Leu His Ser  Met Met Val 
    2900                 2905                 2910             


Arg Ser  Ser His Gln Leu Ser  Lys Gln Ile Ser Asp  Leu Ile Arg 
    2915                 2920                 2925             


Gln Pro  Ser Thr Ala Pro Gln  Pro Val Lys Glu Asp  Ile Ala Thr 
    2930                 2935                 2940             


Pro Leu  Pro Ser Glu Lys Thr  Pro Thr Ser Val Asn  Gln Thr Pro 
    2945                 2950                 2955             


Val Glu  Thr Asn Glu Phe Pro  Gln Leu Pro Glu Gly  Leu Glu Lys 
    2960                 2965                 2970             


Lys Pro  Ile Val Leu Lys Phe  Ser Ala Met Leu Asp  Gly Ile Ala 
    2975                 2980                 2985             


Ile Gly  Ala Ala Leu Leu Pro  Ser Leu Lys Ala Glu  Tyr Lys Met 
    2990                 2995                 3000             


Gly Arg  Met Arg Ser His Gly  Met Thr Gly Ala Gln  Thr Arg Phe 
    3005                 3010                 3015             


Thr Phe  Glu Leu Pro Asn His  Arg Leu Arg Phe Thr  Ser Lys Val 
    3020                 3025                 3030             


Ser Ala  Thr Asp Met Ser Thr  Ile Pro Pro Ser Ala  Ser Leu Asn 
    3035                 3040                 3045             


Leu Pro  Pro Val Thr Met Ser  Gly Lys Tyr Ile Met  Glu Glu His 
    3050                 3055                 3060             


Asp Ser  Tyr Ser Asp Gln Val  Trp Ser Ile Asp Glu  Leu Pro Ser 
    3065                 3070                 3075             


Lys Gln  Gly Tyr Tyr Leu Gln  Gly Asn Tyr Leu Arg  Cys Val Ala 
    3080                 3085                 3090             


Glu Val  Gly Ser Phe Glu His  Asn Leu Thr Thr Asp  Leu Leu Asn 
    3095                 3100                 3105             


His Leu  Val Phe Val Gln Lys  Val Phe Met Lys Glu  Val Asn Glu 
    3110                 3115                 3120             


Val Ile  Gln Lys Val Ser Gly  Gly Glu Gln Pro Ile  Pro Leu Trp 
    3125                 3130                 3135             


Asn Glu  His Asp Gly Thr Ala  Asp Gly Asp Lys Pro  Lys Ile Leu 
    3140                 3145                 3150             


Leu Tyr  Ser Leu Asn Leu Gln  Phe Lys Gly Ile Gln  Val Thr Ala 
    3155                 3160                 3165             


Thr Thr  Pro Ser Met Arg Ala  Val Arg Phe Glu Thr  Gly Leu Ile 
    3170                 3175                 3180             


Glu Leu  Glu Leu Ser Asn Arg  Leu Gln Thr Lys Ala  Ser Pro Gly 
    3185                 3190                 3195             


Ser Ser  Ser Tyr Leu Lys Leu  Phe Gly Lys Cys Gln  Val Asp Leu 
    3200                 3205                 3210             


Asn Leu  Ala Leu Gly Gln Ile  Val Lys His Gln Val  Tyr Glu Glu 
    3215                 3220                 3225             


Ala Gly  Ser Asp Phe His Gln  Val Ala Tyr Phe Lys  Thr Arg Ile 
    3230                 3235                 3240             


Gly Leu  Arg Asn Ala Leu Arg  Glu Glu Ile Ser Gly  Ser Ser Asp 
    3245                 3250                 3255             


Arg Glu  Ala Val Leu Ile Thr  Leu Asn Arg Pro Ile  Val Tyr Ala 
    3260                 3265                 3270             


Gln Pro  Val Ala Phe Asp Arg  Ala Val Leu Phe Trp  Leu Asn Tyr 
    3275                 3280                 3285             


Lys Ala  Ala Tyr Asp Asn Trp  Asn Glu Gln Arg Met  Ala Leu His 
    3290                 3295                 3300             


Lys Asp  Ile His Met Ala Thr  Lys Glu Val Val Asp  Met Leu Pro 
    3305                 3310                 3315             


Gly Ile  Gln Gln Thr Ser Ala  Gln Ala Phe Gly Thr  Leu Phe Leu 
    3320                 3325                 3330             


Gln Leu  Thr Val Asn Asp Leu  Gly Ile Cys Leu Pro  Ile Thr Asn 
    3335                 3340                 3345             


Thr Ala  Gln Ser Asn His Thr  Gly Asp Leu Asp Thr  Gly Ser Ala 
    3350                 3355                 3360             


Leu Val  Leu Thr Ile Glu Ser  Thr Leu Ile Thr Ala  Cys Ser Ser 
    3365                 3370                 3375             


Glu Ser  Leu Val Ser Lys Gly  His Phe Lys Asn Phe  Cys Ile Arg 
    3380                 3385                 3390             


Phe Ala  Asp Gly Phe Glu Thr  Ser Trp Asp Asp Trp  Lys Pro Glu 
    3395                 3400                 3405             


Ile His  Gly Asp Leu Val Met  Asn Ala Cys Val Val  Pro Asp Gly 
    3410                 3415                 3420             


Thr Tyr  Glu Val Cys Ser Arg  Thr Thr Gly Gln Ala  Ala Ala Glu 
    3425                 3430                 3435             


Ser Ser  Ser Ala Gly Thr Trp  Thr Leu Asn Val Leu  Trp Lys Met 
    3440                 3445                 3450             


Cys Gly  Ile Asp Val His Met  Asp Pro Asn Ile Gly  Lys Arg Leu 
    3455                 3460                 3465             


Asn Ala  Leu Gly Asn Thr Leu  Thr Thr Leu Thr Gly  Glu Glu Asp 
    3470                 3475                 3480             


Ile Asp  Asp Ile Ala Asp Leu  Asn Ser Val Asn Ile  Ala Asp Leu 
    3485                 3490                 3495             


Ser Asp  Glu Asp Glu Val Asp  Thr Met Ser Pro Thr  Ile His Thr 
    3500                 3505                 3510             


Glu Ala  Thr Asp Tyr Arg Arg  Gln Ala Ala Ser Ala  Ser Gln Pro 
    3515                 3520                 3525             


Gly Glu  Leu Arg Gly Arg Lys  Ile Met Lys Arg Ile  Val Asp Ile 
    3530                 3535                 3540             


Arg Glu  Leu Asn Glu Gln Ala  Lys Val Ile Asp Asp  Leu Lys Lys 
    3545                 3550                 3555             


Leu Gly  Ala Ser Glu Gly Thr  Ile Asn Gln Glu Ile  Gln Arg Tyr 
    3560                 3565                 3570             


Gln Gln  Leu Glu Ser Val Ala  Val Asn Asp Ile Arg  Arg Asp Val 
    3575                 3580                 3585             


Arg Lys  Lys Leu Arg Arg Ser  Ser Met Arg Ala Ala  Ser Leu Lys 
    3590                 3595                 3600             


Asp Lys  Trp Gly Leu Ser Tyr  Lys Pro Ser Tyr Ser  Arg Ser Lys 
    3605                 3610                 3615             


Ser Ile  Ser Ala Ser Gly Arg  Pro Pro Leu Lys Arg  Met Glu Arg 
    3620                 3625                 3630             


Ala Ser  Ser Arg Val Gly Glu  Thr Glu Glu Leu Pro  Glu Ile Arg 
    3635                 3640                 3645             


Val Asp  Ala Ala Ser Pro Gly  Pro Arg Val Thr Phe  Asn Ile Gln 
    3650                 3655                 3660             


Asp Thr  Phe Pro Glu Glu Thr  Glu Leu Asp Leu Leu  Ser Val Thr 
    3665                 3670                 3675             


Ile Glu  Gly Pro Ser His Tyr  Ser Ser Asn Ser Glu  Gly Ser Cys 
    3680                 3685                 3690             


Ser Val  Phe Ser Ser Pro Lys  Thr Pro Gly Gly Phe  Ser Pro Gly 
    3695                 3700                 3705             


Ile Pro  Phe Gln Thr Glu Glu  Gly Arg Arg Asp Asp  Ser Leu Ser 
    3710                 3715                 3720             


Ser Thr  Ser Glu Asp Ser Glu  Lys Asp Glu Lys Asp  Glu Asp His 
    3725                 3730                 3735             


Glu Arg  Glu Arg Phe Tyr Ile  Tyr Arg Lys Pro Ser  His Thr Ser 
    3740                 3745                 3750             


Arg Lys  Lys Ala Thr Gly Phe  Ala Ala Val His Gln  Leu Phe Thr 
    3755                 3760                 3765             


Glu Arg  Trp Pro Thr Thr Pro  Val Asn Arg Ser Leu  Ser Gly Thr 
    3770                 3775                 3780             


Ala Thr  Glu Arg Asn Ile Asp  Phe Glu Leu Asp Ile  Arg Val Glu 
    3785                 3790                 3795             


Ile Asp  Ser Gly Lys Cys Val  Leu His Pro Thr Thr  Leu Leu Gln 
    3800                 3805                 3810             


Glu His  Asp Asp Ile Ser Leu  Arg Arg Ser Tyr Asp  Arg Ser Ser 
    3815                 3820                 3825             


Arg Ser  Leu Asp Gln Asp Ser  Pro Ser Lys Lys Lys  Lys Phe Gln 
    3830                 3835                 3840             


Thr Asn  Tyr Ala Ser Thr Thr  His Leu Met Thr Gly  Lys Lys Val 
    3845                 3850                 3855             


Pro Ser  Ser Leu Gln Thr Lys  Pro Ser Asp Leu Glu  Thr Thr Val 
    3860                 3865                 3870             


Phe Tyr  Ile Pro Gly Val Asp  Val Lys Leu His Tyr  Asn Ser Lys 
    3875                 3880                 3885             


Thr Leu  Lys Thr Glu Ser Pro  Asn Ala Ser Arg Gly  Ser Ser Leu 
    3890                 3895                 3900             


Pro Arg  Thr Leu Ser Lys Glu  Ser Lys Leu Tyr Gly  Met Lys Asp 
    3905                 3910                 3915             


Ser Ala  Thr Ser Pro Pro Ser  Pro Pro Leu Pro Ser  Thr Val Gln 
    3920                 3925                 3930             


Ser Lys  Thr Asn Thr Leu Leu  Pro Pro Gln Pro Pro  Pro Ile Pro 
    3935                 3940                 3945             


Ala Ala  Lys Gly Lys Gly Ser  Gly Gly Val Lys Thr  Ala Lys Leu 
    3950                 3955                 3960             


Tyr Ala  Trp Val Ala Leu Gln  Ser Leu Pro Glu Glu  Met Val Ile 
    3965                 3970                 3975             


Ser Pro  Cys Leu Leu Asp Phe  Leu Glu Lys Ala Leu  Glu Thr Ile 
    3980                 3985                 3990             


Pro Ile  Thr Pro Val Glu Arg  Asn Tyr Thr Ala Val  Ser Ser Gln 
    3995                 4000                 4005             


Asp Glu  Asp Met Gly His Phe  Glu Ile Pro Asp Pro  Met Glu Glu 
    4010                 4015                 4020             


Ser Thr  Thr Ser Leu Val Ser  Ser Ser Thr Ser Ala  Tyr Ser Ser 
    4025                 4030                 4035             


Phe Pro  Val Asp Val Val Val  Tyr Val Arg Val Gln  Pro Ser Gln 
    4040                 4045                 4050             


Ile Lys  Phe Ser Cys Leu Pro  Val Ser Arg Val Glu  Cys Met Leu 
    4055                 4060                 4065             


Lys Leu  Pro Ser Leu Asp Leu  Val Phe Ser Ser Asn  Arg Gly Glu 
    4070                 4075                 4080             


Leu Glu  Thr Leu Gly Thr Thr  Tyr Pro Ala Glu Thr  Leu Ser Pro 
    4085                 4090                 4095             


Gly Gly  Asn Ala Thr Gln Ser  Gly Thr Lys Thr Ser  Ala Ser Lys 
    4100                 4105                 4110             


Thr Gly  Ile Pro Gly Ser Ser  Gly Leu Gly Ser Pro  Leu Gly Arg 
    4115                 4120                 4125             


Ser Arg  His Ser Ser Ser Gln  Ser Asp Leu Thr Ser  Ser Ser Ser 
    4130                 4135                 4140             


Ser Ser  Ser Gly Leu Ser Phe  Thr Ala Cys Met Ser  Asp Phe Ser 
    4145                 4150                 4155             


Leu Tyr  Val Phe His Pro Tyr  Gly Ala Gly Lys Gln  Lys Thr Ala 
    4160                 4165                 4170             


Val Ser  Gly Leu Thr Pro Gly  Ser Gly Gly Leu Gly  Asn Val Asp 
    4175                 4180                 4185             


Glu Glu  Pro Thr Ser Val Thr  Gly Arg Lys Asp Ser  Leu Ser Ile 
    4190                 4195                 4200             


Asn Leu  Glu Phe Val Lys Val  Ser Leu Ser Arg Ile  Arg Arg Ser 
    4205                 4210                 4215             


Gly Gly  Ala Ser Phe Phe Glu  Ser Gln Ser Val Ser  Lys Ser Ala 
    4220                 4225                 4230             


Ser Lys  Met Asp Thr Thr Leu  Ile Asn Ile Ser Ala  Val Cys Asp 
    4235                 4240                 4245             


Ile Gly  Ser Ala Ser Phe Lys  Tyr Asp Met Arg Arg  Leu Ser Glu 
    4250                 4255                 4260             


Ile Leu  Ala Phe Pro Arg Ala  Trp Tyr Arg Arg Ser  Ile Ala Arg 
    4265                 4270                 4275             


Arg Leu  Phe Leu Gly Asp Gln  Thr Ile Asn Leu Pro  Thr Ser Gly 
    4280                 4285                 4290             


Pro Gly  Thr Pro Asp Ser Ile  Glu Gly Val Ser Gln  His Leu Ser 
    4295                 4300                 4305             


Pro Glu  Ser Ser Arg Lys Ala  Tyr Cys Lys Thr Trp  Glu Gln Pro 
    4310                 4315                 4320             


Ser Gln  Ser Ala Ser Phe Thr  His Met Pro Gln Ser  Pro Asn Val 
    4325                 4330                 4335             


Phe Asn  Glu His Met Thr Asn  Ser Thr Met Ser Pro  Gly Thr Val 
    4340                 4345                 4350             


Gly Gln  Ser Leu Lys Ser Pro  Ala Ser Ile Arg Ser  Arg Ser Val 
    4355                 4360                 4365             


Ser Asp  Ser Ser Val Pro Arg  Arg Asp Ser Leu Ser  Lys Thr Ser 
    4370                 4375                 4380             


Thr Pro  Phe Asn Lys Ser Asn  Lys Ala Ala Ser Gln  Gln Gly Thr 
    4385                 4390                 4395             


Pro Trp  Glu Thr Leu Val Val  Phe Ala Ile Asn Leu  Lys Gln Leu 
    4400                 4405                 4410             


Asn Val  Gln Met Asn Met Ser  Asn Val Met Gly Asn  Thr Thr Trp 
    4415                 4420                 4425             


Thr Thr  Ser Gly Leu Lys Ser  Gln Gly Arg Leu Ser  Val Gly Ser 
    4430                 4435                 4440             


Asn Arg  Asp Arg Glu Ile Ser  Met Ser Val Gly Leu  Gly Arg Ser 
    4445                 4450                 4455             


Gln Leu  Asp Ser Lys Gly Gly  Val Val Gly Gly Thr  Ile Asp Val 
    4460                 4465                 4470             


Asn Ala  Leu Glu Met Val Ala  His Ile Ser Glu His  Pro Asn Gln 
    4475                 4480                 4485             


Gln Pro  Ser His Lys Ile Gln  Ile Thr Met Gly Ser  Thr Glu Ala 
    4490                 4495                 4500             


Arg Val  Asp Tyr Met Gly Ser  Ser Ile Leu Met Gly  Ile Phe Ser 
    4505                 4510                 4515             


Asn Ala  Asp Leu Lys Leu Gln  Asp Glu Trp Lys Val  Asn Leu Tyr 
    4520                 4525                 4530             


Asn Thr  Leu Asp Ser Ser Ile  Thr Asp Lys Ser Glu  Ile Phe Val 
    4535                 4540                 4545             


His Gly  Asp Leu Lys Trp Asp  Ile Phe Gln Val Met  Ile Ser Arg 
    4550                 4555                 4560             


Ser Thr  Thr Pro Asp Leu Ile  Lys Ile Gly Met Lys  Leu Gln Glu 
    4565                 4570                 4575             


Phe Phe  Thr Gln Gln Phe Asp  Thr Ser Lys Arg Ala  Leu Ser Thr 
    4580                 4585                 4590             


Trp Gly  Pro Val Pro Tyr Leu  Pro Pro Lys Thr Met  Thr Ser Asn 
    4595                 4600                 4605             


Leu Glu  Lys Ser Ser Gln Glu  Gln Leu Leu Asp Ala  Ala His His 
    4610                 4615                 4620             


Arg His  Trp Pro Gly Val Leu  Lys Val Val Ser Gly  Cys His Ile 
    4625                 4630                 4635             


Ser Leu  Phe Gln Ile Pro Leu  Pro Glu Asp Gly Met  Gln Phe Gly 
    4640                 4645                 4650             


Gly Ser  Met Ser Leu His Gly  Asn His Met Thr Leu  Ala Cys Phe 
    4655                 4660                 4665             


His Gly  Pro Asn Phe Arg Ser  Lys Ser Trp Ala Leu  Phe His Leu 
    4670                 4675                 4680             


Glu Glu  Pro Asn Ile Ala Phe  Trp Thr Glu Ala Gln  Lys Ile Trp 
    4685                 4690                 4695             


Glu Asp  Gly Ser Ser Asp His  Ser Thr Tyr Ile Val  Gln Thr Leu 
    4700                 4705                 4710             


Asp Phe  His Leu Gly His Asn  Thr Met Val Thr Lys  Pro Cys Gly 
    4715                 4720                 4725             


Ala Leu  Glu Ser Pro Met Ala  Thr Ile Thr Lys Ile  Thr Arg Arg 
    4730                 4735                 4740             


Arg His  Glu Asn Pro Pro His  Gly Val Ala Ser Val  Lys Glu Trp 
    4745                 4750                 4755             


Phe Asn  Tyr Val Thr Ala Thr  Arg Asn Glu Glu Leu  Asn Leu Leu 
    4760                 4765                 4770             


Arg Asn  Val Asp Ala Asn Asn  Thr Glu Asn Ser Thr  Thr Val Lys 
    4775                 4780                 4785             


Asn Ser  Ser Leu Leu Ser Gly  Phe Arg Gly Gly Ser  Ser Tyr Asn 
    4790                 4795                 4800             


His Glu  Thr Glu Thr Ile Phe  Ala Leu Pro Arg Met  Gln Leu Asp 
    4805                 4810                 4815             


Phe Lys  Ser Ile His Val Gln  Glu Pro Gln Glu Pro  Ser Leu Gln 
    4820                 4825                 4830             


Asp Ala  Ser Leu Lys Pro Lys  Val Glu Cys Ser Val  Val Thr Glu 
    4835                 4840                 4845             


Phe Thr  Asp His Ile Cys Val  Thr Met Asp Ala Glu  Leu Ile Met 
    4850                 4855                 4860             


Phe Leu  His Asp Leu Val Ser  Ala Tyr Leu Lys Glu  Lys Glu Lys 
    4865                 4870                 4875             


Ala Ile  Phe Pro Pro Arg Ile  Leu Ser Thr Arg Pro  Gly Gln Lys 
    4880                 4885                 4890             


Ser Pro  Ile Ile Ile His Asp  Asp Asn Ser Ser Asp  Lys Asp Arg 
    4895                 4900                 4905             


Glu Asp  Ser Ile Thr Tyr Thr  Thr Val Asp Trp Arg  Asp Phe Met 
    4910                 4915                 4920             


Cys Asn  Thr Trp His Leu Glu  Pro Thr Leu Arg Leu  Ile Ser Trp 
    4925                 4930                 4935             


Thr Gly  Arg Lys Ile Asp Pro  Val Gly Val Asp Tyr  Ile Leu Gln 
    4940                 4945                 4950             


Lys Leu  Gly Phe His His Ala  Arg Thr Thr Ile Pro  Lys Trp Leu 
    4955                 4960                 4965             


Gln Arg  Gly Val Met Asp Pro  Leu Asp Lys Val Leu  Ser Val Leu 
    4970                 4975                 4980             


Ile Lys  Lys Leu Gly Thr Ala  Leu Gln Asp Glu Lys  Glu Lys Lys 
    4985                 4990                 4995             


Gly Lys  Asp Lys Glu Glu His  
    5000                 5005 


<210>  1343
<211>  483
<212>  PRT
<213>  Human

<400>  1343

Met Ser Ile Arg Val Thr Gln Lys Ser Tyr Lys Val Ser Thr Ser Gly 
1               5                   10                  15      


Pro Arg Ala Phe Ser Ser Arg Ser Tyr Thr Ser Gly Pro Gly Ser Arg 
            20                  25                  30          


Ile Ser Ser Ser Ser Phe Ser Arg Val Gly Ser Ser Asn Phe Arg Gly 
        35                  40                  45              


Gly Leu Gly Gly Gly Tyr Gly Gly Ala Ser Gly Met Gly Gly Ile Thr 
    50                  55                  60                  


Ala Val Thr Val Asn Gln Ser Leu Leu Ser Pro Leu Val Leu Glu Val 
65                  70                  75                  80  


Asp Pro Asn Ile Gln Ala Val Arg Thr Gln Glu Lys Glu Gln Ile Lys 
                85                  90                  95      


Thr Leu Asn Asn Lys Phe Ala Ser Phe Ile Asp Lys Val Arg Phe Leu 
            100                 105                 110         


Glu Gln Gln Asn Lys Met Leu Glu Thr Lys Trp Ser Leu Leu Gln Gln 
        115                 120                 125             


Gln Lys Thr Ala Arg Ser Asn Met Asp Asn Met Phe Glu Ser Tyr Ile 
    130                 135                 140                 


Asn Asn Leu Arg Arg Gln Leu Glu Thr Leu Gly Gln Glu Lys Leu Lys 
145                 150                 155                 160 


Leu Glu Ala Glu Leu Gly Asn Met Gln Gly Leu Val Glu Asp Phe Lys 
                165                 170                 175     


Asn Lys Tyr Glu Asp Glu Ile Asn Lys Arg Thr Glu Met Glu Asn Glu 
            180                 185                 190         


Phe Val Leu Ile Lys Lys Asp Val Asp Glu Ala Tyr Met Asn Lys Val 
        195                 200                 205             


Glu Leu Glu Ser Arg Leu Glu Gly Leu Thr Asp Glu Ile Asn Phe Leu 
    210                 215                 220                 


Arg Gln Leu Tyr Glu Glu Glu Ile Arg Glu Leu Gln Ser Gln Ile Ser 
225                 230                 235                 240 


Asp Thr Ser Val Val Leu Ser Met Asp Asn Ser Arg Ser Leu Asp Met 
                245                 250                 255     


Asp Ser Ile Ile Ala Glu Val Lys Ala Gln Tyr Glu Asp Ile Ala Asn 
            260                 265                 270         


Arg Ser Arg Ala Glu Ala Glu Ser Met Tyr Gln Ile Lys Tyr Glu Glu 
        275                 280                 285             


Leu Gln Ser Leu Ala Gly Lys His Gly Asp Asp Leu Arg Arg Thr Lys 
    290                 295                 300                 


Thr Glu Ile Ser Glu Met Asn Arg Asn Ile Ser Arg Leu Gln Ala Glu 
305                 310                 315                 320 


Ile Glu Gly Leu Lys Gly Gln Arg Ala Ser Leu Glu Ala Ala Ile Ala 
                325                 330                 335     


Asp Ala Glu Gln Arg Gly Glu Leu Ala Ile Lys Asp Ala Asn Ala Lys 
            340                 345                 350         


Leu Ser Glu Leu Glu Ala Ala Leu Gln Arg Ala Lys Gln Asp Met Ala 
        355                 360                 365             


Arg Gln Leu Arg Glu Tyr Gln Glu Leu Met Asn Val Lys Leu Ala Leu 
    370                 375                 380                 


Asp Ile Glu Ile Ala Thr Tyr Arg Lys Leu Leu Glu Gly Glu Glu Ser 
385                 390                 395                 400 


Arg Leu Glu Ser Gly Met Gln Asn Met Ser Ile His Thr Lys Thr Thr 
                405                 410                 415     


Ser Gly Tyr Ala Gly Gly Leu Ser Ser Ala Tyr Gly Gly Leu Thr Ser 
            420                 425                 430         


Pro Gly Leu Ser Tyr Ser Leu Gly Ser Ser Phe Gly Ser Gly Ala Gly 
        435                 440                 445             


Ser Ser Ser Phe Ser Arg Thr Ser Ser Ser Arg Ala Val Val Val Lys 
    450                 455                 460                 


Lys Ile Glu Thr Arg Asp Gly Lys Leu Val Ser Glu Ser Ser Asp Val 
465                 470                 475                 480 


Leu Pro Lys 
            


<210>  1344
<211>  1019
<212>  PRT
<213>  Human

<400>  1344

Met Leu Trp Arg Val Leu Leu Ser Lys Arg Pro Pro Phe Pro His Pro 
1               5                   10                  15      


Glu Leu Asp Phe Gln Glu Ala Pro Ile Pro Ser Cys Pro Gly Arg Leu 
            20                  25                  30          


Pro Gly Arg Lys Asn Ser Val Ala Leu Ala Ala Ala Pro Arg Lys Glu 
        35                  40                  45              


Pro Thr Gly Asp Arg Glu Lys Pro Leu Pro Phe Pro Val Leu Ala Pro 
    50                  55                  60                  


Phe Ser Asn Pro Glu His Ser Ala Pro Ala Lys Val Val Arg Ala Ala 
65                  70                  75                  80  


Val Pro Lys Gln Arg Lys Gly Ser Lys Val Gly Asp Phe Gly Asp Ala 
                85                  90                  95      


Ile Asn Trp Pro Thr Pro Gly Glu Ile Ala His Lys Ser Val Gln Pro 
            100                 105                 110         


Gln Ser His Lys Pro Gln Pro Thr Arg Lys Leu Pro Pro Lys Lys Asp 
        115                 120                 125             


Met Lys Glu Gln Glu Lys Gly Glu Gly Ser Asp Ser Lys Glu Ser Pro 
    130                 135                 140                 


Lys Thr Lys Ser Asp Glu Ser Gly Glu Glu Lys Asn Gly Asp Glu Asp 
145                 150                 155                 160 


Cys Gln Arg Gly Gly Gln Lys Lys Lys Gly Asn Lys His Lys Trp Val 
                165                 170                 175     


Pro Leu Gln Ile Asp Met Lys Pro Glu Val Pro Arg Glu Lys Leu Ala 
            180                 185                 190         


Ser Arg Pro Thr Arg Pro Pro Glu Pro Arg His Ile Pro Ala Asn Arg 
        195                 200                 205             


Gly Glu Ile Lys Gly Ser Glu Ser Ala Thr Tyr Val Pro Val Ala Pro 
    210                 215                 220                 


Pro Thr Pro Ala Trp Gln Pro Glu Ile Lys Pro Glu Pro Ala Trp His 
225                 230                 235                 240 


Asp Gln Asp Glu Thr Ser Ser Val Lys Ser Asp Gly Ala Gly Gly Ala 
                245                 250                 255     


Arg Ala Ser Phe Arg Gly Arg Gly Arg Gly Arg Gly Arg Gly Arg Gly 
            260                 265                 270         


Arg Gly Arg Gly Gly Thr Arg Thr His Phe Asp Tyr Gln Phe Gly Tyr 
        275                 280                 285             


Arg Lys Phe Asp Gly Val Glu Gly Pro Arg Thr Pro Lys Tyr Met Asn 
    290                 295                 300                 


Asn Ile Thr Tyr Tyr Phe Asp Asn Val Ser Ser Thr Glu Leu Tyr Ser 
305                 310                 315                 320 


Val Asp Gln Glu Leu Leu Lys Asp Tyr Ile Lys Arg Gln Ile Glu Tyr 
                325                 330                 335     


Tyr Phe Ser Val Asp Asn Leu Glu Arg Asp Phe Phe Leu Arg Arg Lys 
            340                 345                 350         


Met Asp Ala Asp Gly Phe Leu Pro Ile Thr Leu Ile Ala Ser Phe His 
        355                 360                 365             


Arg Val Gln Ala Leu Thr Thr Asp Ile Ser Leu Ile Phe Ala Ala Leu 
    370                 375                 380                 


Lys Asp Ser Lys Val Val Glu Ile Val Asp Glu Lys Val Arg Arg Arg 
385                 390                 395                 400 


Glu Glu Pro Glu Lys Trp Pro Leu Pro Pro Ile Val Asp Tyr Ser Gln 
                405                 410                 415     


Thr Asp Phe Ser Gln Leu Leu Asn Cys Pro Glu Phe Val Pro Arg Gln 
            420                 425                 430         


His Tyr Gln Lys Glu Thr Glu Ser Ala Pro Gly Ser Pro Arg Ala Val 
        435                 440                 445             


Thr Pro Val Pro Thr Lys Thr Glu Glu Val Ser Asn Leu Lys Thr Leu 
    450                 455                 460                 


Pro Lys Gly Leu Ser Ala Ser Leu Pro Asp Leu Asp Ser Glu Asn Trp 
465                 470                 475                 480 


Ile Glu Val Lys Lys Arg Pro Arg Pro Ser Pro Ala Arg Pro Lys Lys 
                485                 490                 495     


Ser Glu Glu Ser Arg Phe Ser His Leu Thr Ser Leu Pro Gln Gln Leu 
            500                 505                 510         


Pro Ser Gln Gln Leu Met Ser Lys Asp Gln Asp Glu Gln Glu Glu Leu 
        515                 520                 525             


Asp Phe Leu Phe Asp Glu Glu Met Glu Gln Met Asp Gly Arg Lys Asn 
    530                 535                 540                 


Thr Phe Thr Ala Trp Ser Asp Glu Glu Ser Asp Tyr Glu Ile Asp Asp 
545                 550                 555                 560 


Arg Asp Val Asn Lys Ile Leu Ile Val Thr Gln Thr Pro His Tyr Met 
                565                 570                 575     


Arg Arg His Pro Gly Gly Asp Arg Thr Gly Asn His Thr Ser Arg Ala 
            580                 585                 590         


Lys Met Ser Ala Glu Leu Ala Lys Val Ile Asn Asp Gly Leu Phe Tyr 
        595                 600                 605             


Tyr Glu Gln Asp Leu Trp Ala Glu Lys Phe Glu Pro Glu Tyr Ser Gln 
    610                 615                 620                 


Ile Lys Gln Glu Val Glu Asn Phe Lys Lys Val Asn Met Ile Ser Arg 
625                 630                 635                 640 


Glu Gln Phe Asp Thr Leu Thr Pro Glu Pro Pro Val Asp Pro Asn Gln 
                645                 650                 655     


Glu Val Pro Pro Gly Pro Pro Arg Phe Gln Gln Val Pro Thr Asp Ala 
            660                 665                 670         


Leu Ala Asn Lys Leu Phe Gly Ala Pro Glu Pro Ser Thr Ile Ala Arg 
        675                 680                 685             


Ser Leu Pro Thr Thr Val Pro Glu Ser Pro Asn Tyr Arg Asn Thr Arg 
    690                 695                 700                 


Thr Pro Arg Thr Pro Arg Thr Pro Gln Leu Lys Asp Ser Ser Gln Thr 
705                 710                 715                 720 


Ser Arg Phe Tyr Pro Val Val Lys Glu Gly Arg Thr Leu Asp Ala Lys 
                725                 730                 735     


Met Pro Arg Lys Arg Lys Thr Arg His Ser Ser Asn Pro Pro Leu Glu 
            740                 745                 750         


Ser His Val Gly Trp Val Met Asp Ser Arg Glu His Arg Pro Arg Thr 
        755                 760                 765             


Ala Ser Ile Ser Ser Ser Pro Ser Glu Gly Thr Pro Thr Val Gly Ser 
    770                 775                 780                 


Tyr Gly Cys Thr Pro Gln Ser Leu Pro Lys Phe Gln His Pro Ser His 
785                 790                 795                 800 


Glu Leu Leu Lys Glu Asn Gly Phe Thr Gln His Val Tyr His Lys Tyr 
                805                 810                 815     


Arg Arg Arg Cys Leu Asn Glu Arg Lys Arg Leu Gly Ile Gly Gln Ser 
            820                 825                 830         


Gln Glu Met Asn Thr Leu Phe Arg Phe Trp Ser Phe Phe Leu Arg Asp 
        835                 840                 845             


His Phe Asn Lys Lys Met Tyr Glu Glu Phe Lys Gln Leu Ala Leu Glu 
    850                 855                 860                 


Asp Ala Lys Glu Gly Tyr Arg Tyr Gly Leu Glu Cys Leu Phe Arg Tyr 
865                 870                 875                 880 


Tyr Ser Tyr Gly Leu Glu Lys Lys Phe Arg Leu Asp Ile Phe Lys Asp 
                885                 890                 895     


Phe Gln Glu Glu Thr Val Lys Asp Tyr Glu Ala Gly Gln Leu Tyr Gly 
            900                 905                 910         


Leu Glu Lys Phe Trp Ala Phe Leu Lys Tyr Ser Lys Ala Lys Asn Leu 
        915                 920                 925             


Asp Ile Asp Pro Lys Leu Gln Glu Tyr Leu Gly Lys Phe Arg Arg Leu 
    930                 935                 940                 


Glu Asp Phe Arg Val Asp Pro Pro Met Gly Glu Glu Gly Asn His Lys 
945                 950                 955                 960 


Arg His Ser Val Val Ala Gly Gly Gly Gly Gly Glu Gly Arg Lys Arg 
                965                 970                 975     


Cys Pro Ser Gln Ser Ser Ser Arg Pro Ala Ala Met Ile Ser Gln Pro 
            980                 985                 990         


Pro Thr Pro Pro Thr Gly Gln Pro  Val Arg Glu Asp Ala  Lys Trp Thr 
        995                 1000                 1005             


Ser Gln  His Ser Asn Thr Gln  Thr Leu Gly Lys 
    1010                 1015                 


<210>  1345
<211>  586
<212>  PRT
<213>  Human

<400>  1345

Met Ala Thr Ala Thr Pro Val Pro Pro Arg Met Gly Ser Arg Ala Gly 
1               5                   10                  15      


Gly Pro Thr Thr Pro Leu Ser Pro Thr Arg Leu Ser Arg Leu Gln Glu 
            20                  25                  30          


Lys Glu Glu Leu Arg Glu Leu Asn Asp Arg Leu Ala Val Tyr Ile Asp 
        35                  40                  45              


Lys Val Arg Ser Leu Glu Thr Glu Asn Ser Ala Leu Gln Leu Gln Val 
    50                  55                  60                  


Thr Glu Arg Glu Glu Val Arg Gly Arg Glu Leu Thr Gly Leu Lys Ala 
65                  70                  75                  80  


Leu Tyr Glu Thr Glu Leu Ala Asp Ala Arg Arg Ala Leu Asp Asp Thr 
                85                  90                  95      


Ala Arg Glu Arg Ala Lys Leu Gln Ile Glu Leu Gly Lys Cys Lys Ala 
            100                 105                 110         


Glu His Asp Gln Leu Leu Leu Asn Tyr Ala Lys Lys Glu Ser Asp Leu 
        115                 120                 125             


Asn Gly Ala Gln Ile Lys Leu Arg Glu Tyr Glu Ala Ala Leu Asn Ser 
    130                 135                 140                 


Lys Asp Ala Ala Leu Ala Thr Ala Leu Gly Asp Lys Lys Ser Leu Glu 
145                 150                 155                 160 


Gly Asp Leu Glu Asp Leu Lys Asp Gln Ile Ala Gln Leu Glu Ala Ser 
                165                 170                 175     


Leu Ala Ala Ala Lys Lys Gln Leu Ala Asp Glu Thr Leu Leu Lys Val 
            180                 185                 190         


Asp Leu Glu Asn Arg Cys Gln Ser Leu Thr Glu Asp Leu Glu Phe Arg 
        195                 200                 205             


Lys Ser Met Tyr Glu Glu Glu Ile Asn Glu Thr Arg Arg Lys His Glu 
    210                 215                 220                 


Thr Arg Leu Val Glu Val Asp Ser Gly Arg Gln Ile Glu Tyr Glu Tyr 
225                 230                 235                 240 


Lys Leu Ala Gln Ala Leu His Glu Met Arg Glu Gln His Asp Ala Gln 
                245                 250                 255     


Val Arg Leu Tyr Lys Glu Glu Leu Glu Gln Thr Tyr His Ala Lys Leu 
            260                 265                 270         


Glu Asn Ala Arg Leu Ser Ser Glu Met Asn Thr Ser Thr Val Asn Ser 
        275                 280                 285             


Ala Arg Glu Glu Leu Met Glu Ser Arg Met Arg Ile Glu Ser Leu Ser 
    290                 295                 300                 


Ser Gln Leu Ser Asn Leu Gln Lys Glu Ser Arg Ala Cys Leu Glu Arg 
305                 310                 315                 320 


Ile Gln Glu Leu Glu Asp Leu Leu Ala Lys Glu Lys Asp Asn Ser Arg 
                325                 330                 335     


Arg Met Leu Thr Asp Lys Glu Arg Glu Met Ala Glu Ile Arg Asp Gln 
            340                 345                 350         


Met Gln Gln Gln Leu Asn Asp Tyr Glu Gln Leu Leu Asp Val Lys Leu 
        355                 360                 365             


Ala Leu Asp Met Glu Ile Ser Ala Tyr Arg Lys Leu Leu Glu Gly Glu 
    370                 375                 380                 


Glu Glu Arg Leu Lys Leu Ser Pro Ser Pro Ser Ser Arg Val Thr Val 
385                 390                 395                 400 


Ser Arg Ala Ser Ser Ser Arg Ser Val Arg Thr Thr Arg Gly Lys Arg 
                405                 410                 415     


Lys Arg Val Asp Val Glu Glu Ser Glu Ala Ser Ser Ser Val Ser Ile 
            420                 425                 430         


Ser His Ser Ala Ser Ala Thr Gly Asn Val Cys Ile Glu Glu Ile Asp 
        435                 440                 445             


Val Asp Gly Lys Phe Ile Arg Leu Lys Asn Thr Ser Glu Gln Asp Gln 
    450                 455                 460                 


Pro Met Gly Gly Trp Glu Met Ile Arg Lys Ile Gly Asp Thr Ser Val 
465                 470                 475                 480 


Ser Tyr Lys Tyr Thr Ser Arg Tyr Val Leu Lys Ala Gly Gln Thr Val 
                485                 490                 495     


Thr Ile Trp Ala Ala Asn Ala Gly Val Thr Ala Ser Pro Pro Thr Asp 
            500                 505                 510         


Leu Ile Trp Lys Asn Gln Asn Ser Trp Gly Thr Gly Glu Asp Val Lys 
        515                 520                 525             


Val Ile Leu Lys Asn Ser Gln Gly Glu Glu Val Ala Gln Arg Ser Thr 
    530                 535                 540                 


Val Phe Lys Thr Thr Ile Pro Glu Glu Glu Glu Glu Glu Glu Glu Ala 
545                 550                 555                 560 


Ala Gly Val Val Val Glu Glu Glu Leu Phe His Gln Gln Gly Thr Pro 
                565                 570                 575     


Arg Ala Ser Asn Arg Ser Cys Ala Ile Met 
            580                 585     


<210>  1346
<211>  534
<212>  PRT
<213>  Human

<400>  1346

Met Arg Leu Arg Gly Cys Gly Pro Arg Ala Ala Pro Ala Ser Ser Ala 
1               5                   10                  15      


Gly Ala Ser Asp Ala Arg Leu Leu Ala Pro Pro Gly Arg Asn Pro Phe 
            20                  25                  30          


Val His Glu Leu Arg Leu Ser Ala Leu Gln Lys Ala Gln Val Ala Leu 
        35                  40                  45              


Met Thr Leu Thr Leu Phe Pro Val Arg Leu Leu Val Ala Ala Ala Met 
    50                  55                  60                  


Met Leu Leu Ala Trp Pro Leu Ala Leu Val Ala Ser Leu Gly Ser Ala 
65                  70                  75                  80  


Glu Lys Glu Pro Glu Gln Pro Pro Ala Leu Trp Arg Lys Val Val Asp 
                85                  90                  95      


Phe Leu Leu Lys Ala Ile Met Arg Thr Met Trp Phe Ala Gly Gly Phe 
            100                 105                 110         


His Arg Val Ala Val Lys Gly Arg Gln Ala Leu Pro Thr Glu Ala Ala 
        115                 120                 125             


Ile Leu Thr Leu Ala Pro His Ser Ser Tyr Phe Asp Ala Ile Pro Val 
    130                 135                 140                 


Thr Met Thr Met Ser Ser Ile Val Met Lys Ala Glu Ser Arg Asp Ile 
145                 150                 155                 160 


Pro Ile Trp Gly Thr Leu Ile Gln Tyr Ile Arg Pro Val Phe Val Ser 
                165                 170                 175     


Arg Ser Asp Gln Asp Ser Arg Arg Lys Thr Val Glu Glu Ile Lys Arg 
            180                 185                 190         


Arg Ala Gln Ser Asn Gly Lys Trp Pro Gln Ile Met Ile Phe Pro Glu 
        195                 200                 205             


Gly Thr Cys Thr Asn Arg Thr Cys Leu Ile Thr Phe Lys Pro Gly Ala 
    210                 215                 220                 


Phe Ile Pro Gly Ala Pro Val Gln Pro Val Val Leu Arg Tyr Pro Asn 
225                 230                 235                 240 


Lys Leu Asp Thr Ile Thr Trp Thr Trp Gln Gly Pro Gly Ala Leu Glu 
                245                 250                 255     


Ile Leu Trp Leu Thr Leu Cys Gln Phe His Asn Gln Val Glu Ile Glu 
            260                 265                 270         


Phe Leu Pro Val Tyr Ser Pro Ser Glu Glu Glu Lys Arg Asn Pro Ala 
        275                 280                 285             


Leu Tyr Ala Ser Asn Val Arg Arg Val Met Ala Glu Ala Leu Gly Val 
    290                 295                 300                 


Ser Val Thr Asp Tyr Thr Phe Glu Asp Cys Gln Leu Ala Leu Ala Glu 
305                 310                 315                 320 


Gly Gln Leu Arg Leu Pro Ala Asp Thr Cys Leu Leu Glu Phe Ala Arg 
                325                 330                 335     


Leu Val Arg Gly Leu Gly Leu Lys Pro Glu Lys Leu Glu Lys Asp Leu 
            340                 345                 350         


Asp Arg Tyr Ser Glu Arg Ala Arg Met Lys Gly Gly Glu Lys Ile Gly 
        355                 360                 365             


Ile Ala Glu Phe Ala Ala Ser Leu Glu Val Pro Val Ser Asp Leu Leu 
    370                 375                 380                 


Glu Asp Met Phe Ser Leu Phe Asp Glu Ser Gly Ser Gly Glu Val Asp 
385                 390                 395                 400 


Leu Arg Glu Cys Val Val Ala Leu Ser Val Val Cys Arg Pro Ala Arg 
                405                 410                 415     


Thr Leu Asp Thr Ile Gln Leu Ala Phe Lys Met Tyr Gly Ala Gln Glu 
            420                 425                 430         


Asp Gly Ser Val Gly Glu Gly Asp Leu Ser Cys Ile Leu Lys Thr Ala 
        435                 440                 445             


Leu Gly Val Ala Glu Leu Thr Val Thr Asp Leu Phe Arg Ala Ile Asp 
    450                 455                 460                 


Gln Glu Glu Lys Gly Lys Ile Thr Phe Ala Asp Phe His Arg Phe Ala 
465                 470                 475                 480 


Glu Met Tyr Pro Ala Phe Ala Glu Glu Tyr Leu Tyr Pro Asp Gln Thr 
                485                 490                 495     


His Phe Glu Ser Cys Ala Glu Thr Ser Pro Ala Pro Ile Pro Asn Gly 
            500                 505                 510         


Phe Cys Ala Asp Phe Ser Pro Glu Asn Ser Asp Ala Gly Arg Lys Pro 
        515                 520                 525             


Val Arg Lys Lys Leu Asp 
    530                 


<210>  1347
<211>  606
<212>  PRT
<213>  Human

<400>  1347

Met Ser Asp Thr Ser Glu Ser Gly Ala Gly Leu Thr Arg Phe Gln Ala 
1               5                   10                  15      


Glu Ala Ser Glu Lys Asp Ser Ser Ser Met Met Gln Thr Leu Leu Thr 
            20                  25                  30          


Val Thr Gln Asn Val Glu Val Pro Glu Thr Pro Lys Ala Ser Lys Ala 
        35                  40                  45              


Leu Glu Val Ser Glu Asp Val Lys Val Ser Lys Ala Ser Gly Val Ser 
    50                  55                  60                  


Lys Ala Thr Glu Val Ser Lys Thr Pro Glu Ala Arg Glu Ala Pro Ala 
65                  70                  75                  80  


Thr Gln Ala Ser Ser Thr Thr Gln Leu Thr Asp Thr Gln Val Leu Ala 
                85                  90                  95      


Ala Glu Asn Lys Ser Leu Ala Ala Asp Thr Lys Lys Gln Asn Ala Asp 
            100                 105                 110         


Pro Gln Ala Val Thr Met Pro Ala Thr Glu Thr Lys Lys Val Ser His 
        115                 120                 125             


Val Ala Asp Thr Lys Val Asn Thr Lys Ala Gln Glu Thr Glu Ala Ala 
    130                 135                 140                 


Pro Ser Gln Ala Pro Ala Asp Glu Pro Glu Pro Glu Ser Ala Ala Ala 
145                 150                 155                 160 


Gln Ser Gln Glu Asn Gln Asp Thr Arg Pro Lys Val Lys Ala Lys Lys 
                165                 170                 175     


Ala Arg Lys Val Lys His Leu Asp Gly Glu Glu Asp Gly Ser Ser Asp 
            180                 185                 190         


Gln Ser Gln Ala Ser Gly Thr Thr Gly Gly Arg Arg Val Ser Lys Ala 
        195                 200                 205             


Leu Met Ala Ser Met Ala Arg Arg Ala Ser Arg Gly Pro Ile Ala Phe 
    210                 215                 220                 


Trp Ala Arg Arg Ala Ser Arg Thr Arg Leu Ala Ala Trp Ala Arg Arg 
225                 230                 235                 240 


Ala Leu Leu Ser Leu Arg Ser Pro Lys Ala Arg Arg Gly Lys Ala Arg 
                245                 250                 255     


Arg Arg Ala Ala Lys Leu Gln Ser Ser Gln Glu Pro Glu Ala Pro Pro 
            260                 265                 270         


Pro Arg Asp Val Ala Leu Leu Gln Gly Arg Ala Asn Asp Leu Val Lys 
        275                 280                 285             


Tyr Leu Leu Ala Lys Asp Gln Thr Lys Ile Pro Ile Lys Arg Ser Asp 
    290                 295                 300                 


Met Leu Lys Asp Ile Ile Lys Glu Tyr Thr Asp Val Tyr Pro Glu Ile 
305                 310                 315                 320 


Ile Glu Arg Ala Gly Tyr Ser Leu Glu Lys Val Phe Gly Ile Gln Leu 
                325                 330                 335     


Lys Glu Ile Asp Lys Asn Asp His Leu Tyr Ile Leu Leu Ser Thr Leu 
            340                 345                 350         


Glu Pro Thr Asp Ala Gly Ile Leu Gly Thr Thr Lys Asp Ser Pro Lys 
        355                 360                 365             


Leu Gly Leu Leu Met Val Leu Leu Ser Ile Ile Phe Met Asn Gly Asn 
    370                 375                 380                 


Arg Ser Ser Glu Ala Val Ile Trp Glu Val Leu Arg Lys Leu Gly Leu 
385                 390                 395                 400 


Arg Pro Gly Ile His His Ser Leu Phe Gly Asp Val Lys Lys Leu Ile 
                405                 410                 415     


Thr Asp Glu Phe Val Lys Gln Lys Tyr Leu Asp Tyr Ala Arg Val Pro 
            420                 425                 430         


Asn Ser Asn Pro Pro Glu Tyr Glu Phe Phe Trp Gly Leu Arg Ser Tyr 
        435                 440                 445             


Tyr Glu Thr Ser Lys Met Lys Val Leu Lys Phe Ala Cys Lys Val Gln 
    450                 455                 460                 


Lys Lys Asp Pro Lys Glu Trp Ala Ala Gln Tyr Arg Glu Ala Met Glu 
465                 470                 475                 480 


Ala Asp Leu Lys Ala Ala Ala Glu Ala Ala Ala Glu Ala Lys Ala Arg 
                485                 490                 495     


Ala Glu Ile Arg Ala Arg Met Gly Ile Gly Leu Gly Ser Glu Asn Ala 
            500                 505                 510         


Ala Gly Pro Cys Asn Trp Asp Glu Ala Asp Ile Gly Pro Trp Ala Lys 
        515                 520                 525             


Ala Arg Ile Gln Ala Gly Ala Glu Ala Lys Ala Lys Ala Gln Glu Ser 
    530                 535                 540                 


Gly Ser Ala Ser Thr Gly Ala Ser Thr Ser Thr Asn Asn Ser Ala Ser 
545                 550                 555                 560 


Ala Ser Ala Ser Thr Ser Gly Gly Phe Ser Ala Gly Ala Ser Leu Thr 
                565                 570                 575     


Ala Thr Leu Thr Phe Gly Leu Phe Ala Gly Leu Gly Gly Ala Gly Ala 
            580                 585                 590         


Ser Thr Ser Gly Ser Ser Gly Ala Cys Gly Phe Ser Tyr Lys 
        595                 600                 605     


<210>  1348
<211>  813
<212>  PRT
<213>  Human

<400>  1348

Asp Pro Glu Thr Pro Ser Asp Ala Ala Ala Met Glu Ser Gly Pro Arg 
1               5                   10                  15      


Ala Glu Leu Gly Ala Gly Ala Pro Pro Ala Val Val Ala Arg Thr Pro 
            20                  25                  30          


Pro Glu Pro Arg Pro Ser Pro Glu Gly Asp Pro Ser Pro Pro Pro Pro 
        35                  40                  45              


Pro Met Ser Ala Leu Val Pro Asp Thr Pro Pro Asp Thr Pro Pro Ala 
    50                  55                  60                  


Met Lys Asn Ala Thr Ser Ser Lys Gln Leu Pro Leu Glu Pro Glu Ser 
65                  70                  75                  80  


Pro Ser Gly Gln Val Gly Pro Arg Pro Ala Pro Pro Gln Glu Glu Ser 
                85                  90                  95      


Pro Ser Ser Glu Ala Lys Ser Arg Gly Pro Thr Pro Pro Ala Met Gly 
            100                 105                 110         


Pro Arg Asp Ala Arg Pro Pro Arg Arg Ser Ser Gln Pro Ser Pro Thr 
        115                 120                 125             


Ala Val Pro Ala Ser Asp Ser Pro Pro Thr Lys Gln Glu Val Lys Lys 
    130                 135                 140                 


Ala Gly Glu Arg His Lys Leu Ala Lys Glu Arg Arg Glu Glu Arg Ala 
145                 150                 155                 160 


Lys Tyr Leu Ala Ala Lys Lys Ala Val Trp Leu Glu Lys Glu Glu Lys 
                165                 170                 175     


Ala Lys Ala Leu Arg Glu Lys Gln Leu Gln Glu Arg Arg Arg Arg Leu 
            180                 185                 190         


Glu Glu Gln Arg Leu Lys Ala Glu Gln Arg Arg Ala Ala Leu Glu Glu 
        195                 200                 205             


Arg Gln Arg Gln Lys Leu Glu Lys Asn Lys Glu Arg Tyr Glu Ala Ala 
    210                 215                 220                 


Ile Gln Arg Ser Val Lys Lys Thr Trp Ala Glu Ile Arg Gln Gln Arg 
225                 230                 235                 240 


Trp Ser Trp Ala Gly Ala Leu His His Ser Ser Pro Gly His Lys Thr 
                245                 250                 255     


Asn Arg Ser Leu Gln Leu Ser Ala Trp Glu Ser Ser Ile Val Asp Arg 
            260                 265                 270         


Leu Met Thr Pro Thr Leu Ser Phe Leu Ala Arg Ser Arg Ser Ala Val 
        275                 280                 285             


Thr Leu Pro Arg Asn Gly Arg Asp Gln Gly Arg Gly Cys Asp Pro Gly 
    290                 295                 300                 


Arg Gly Pro Thr Trp Gly Arg Ala Gly Ala Ser Leu Ala Arg Gly Pro 
305                 310                 315                 320 


Gln Pro Asp Arg Thr His Pro Ser Ala Ala Val Pro Val Cys Pro Arg 
                325                 330                 335     


Ser Ala Ser Ala Ser Pro Leu Thr Pro Cys Ser Val Thr Arg Ser Val 
            340                 345                 350         


His Arg Cys Ala Pro Ala Gly Glu Arg Gly Glu Arg Arg Lys Pro Asn 
        355                 360                 365             


Ala Gly Gly Ser Pro Ala Pro Val Arg Arg Arg Pro Glu Ala Ser Pro 
    370                 375                 380                 


Val Gln Lys Lys Glu Lys Lys Asp Lys Glu Arg Glu Asn Glu Lys Glu 
385                 390                 395                 400 


Lys Ser Ala Leu Ala Arg Glu Arg Ser Leu Lys Lys Arg Gln Ser Leu 
                405                 410                 415     


Pro Ala Ser Pro Arg Ala Arg Leu Ser Ala Ser Thr Ala Ser Glu Leu 
            420                 425                 430         


Ser Pro Lys Ser Lys Ala Arg Pro Ser Ser Pro Ser Thr Ser Trp His 
        435                 440                 445             


Arg Pro Ala Ser Pro Cys Pro Ser Pro Gly Pro Gly His Thr Leu Pro 
    450                 455                 460                 


Pro Lys Pro Pro Ser Pro Arg Gly Thr Thr Ala Ser Pro Lys Gly Arg 
465                 470                 475                 480 


Val Arg Arg Lys Glu Glu Ala Lys Glu Ser Pro Ser Ala Ala Gly Pro 
                485                 490                 495     


Glu Asp Lys Ser Gln Ser Lys Arg Arg Ala Ser Asn Glu Lys Glu Ser 
            500                 505                 510         


Ala Ala Pro Ala Ser Pro Ala Pro Ser Pro Ala Pro Ser Pro Thr Pro 
        515                 520                 525             


Ala Pro Pro Gln Lys Glu Gln Pro Pro Ala Glu Thr Pro Thr Asp Ala 
    530                 535                 540                 


Ala Val Leu Thr Ser Pro Pro Ala Pro Ala Pro Pro Val Thr Pro Ser 
545                 550                 555                 560 


Lys Pro Met Ala Gly Thr Thr Asp Arg Glu Glu Ala Thr Arg Leu Leu 
                565                 570                 575     


Ala Glu Lys Arg Arg Gln Ala Arg Glu Gln Arg Glu Arg Glu Glu Gln 
            580                 585                 590         


Glu Arg Arg Leu Gln Ala Glu Arg Asp Lys Arg Met Arg Glu Glu Gln 
        595                 600                 605             


Leu Ala Arg Glu Ala Glu Ala Arg Ala Glu Arg Glu Ala Glu Ala Arg 
    610                 615                 620                 


Arg Arg Glu Glu Gln Glu Ala Arg Glu Lys Ala Gln Ala Glu Gln Glu 
625                 630                 635                 640 


Glu Gln Glu Arg Leu Gln Lys Gln Lys Glu Glu Ala Glu Ala Arg Ser 
                645                 650                 655     


Arg Glu Glu Ala Glu Arg Gln Arg Leu Glu Arg Glu Lys His Phe Gln 
            660                 665                 670         


Gln Gln Glu Gln Glu Arg Gln Glu Arg Arg Lys Arg Leu Glu Glu Ile 
        675                 680                 685             


Met Lys Arg Thr Arg Lys Ser Glu Val Ser Glu Thr Lys Lys Gln Asp 
    690                 695                 700                 


Ser Lys Glu Ala Asn Ala Asn Gly Ser Ser Pro Glu Pro Val Lys Ala 
705                 710                 715                 720 


Val Glu Ala Arg Ser Pro Gly Leu Gln Lys Glu Ala Val Gln Lys Glu 
                725                 730                 735     


Glu Pro Ile Pro Gln Glu Pro Gln Trp Ser Leu Pro Ser Lys Glu Leu 
            740                 745                 750         


Pro Ala Ser Leu Val Asn Gly Leu Gln Pro Leu Pro Ala His Gln Glu 
        755                 760                 765             


Asn Gly Phe Ser Thr Asn Gly Pro Ser Gly Asp Lys Ser Leu Ser Arg 
    770                 775                 780                 


Thr Pro Glu Thr Leu Leu Pro Phe Ala Glu Ala Glu Ala Phe Leu Lys 
785                 790                 795                 800 


Lys Ala Val Val Gln Ser Pro Gln Val Thr Glu Val Leu 
                805                 810             


<210>  1349
<211>  426
<212>  PRT
<213>  Human

<400>  1349

Met Ser Lys Ser Lys Val Asp Asn Gln Phe Tyr Ser Val Glu Val Gly 
1               5                   10                  15      


Asp Ser Thr Phe Thr Val Leu Lys Arg Tyr Gln Asn Leu Lys Pro Ile 
            20                  25                  30          


Gly Ser Gly Ala Gln Gly Ile Val Cys Ala Ala Tyr Asp Ala Val Leu 
        35                  40                  45              


Asp Arg Asn Val Ala Ile Lys Lys Leu Ser Arg Pro Phe Gln Asn Gln 
    50                  55                  60                  


Thr His Ala Lys Arg Ala Tyr Arg Glu Leu Val Leu Met Lys Cys Val 
65                  70                  75                  80  


Asn His Lys Asn Ile Ile Ser Leu Leu Asn Val Phe Thr Pro Gln Lys 
                85                  90                  95      


Thr Leu Glu Glu Phe Gln Asp Val Tyr Leu Val Met Glu Leu Met Asp 
            100                 105                 110         


Ala Asn Leu Cys Gln Val Ile Gln Met Glu Leu Asp His Glu Arg Met 
        115                 120                 125             


Ser Tyr Leu Leu Tyr Gln Met Leu Cys Gly Ile Lys His Leu His Ser 
    130                 135                 140                 


Ala Gly Ile Ile His Arg Asp Leu Lys Pro Ser Asn Ile Val Val Lys 
145                 150                 155                 160 


Ser Asp Cys Thr Leu Lys Ile Leu Asp Phe Gly Leu Ala Arg Thr Ala 
                165                 170                 175     


Gly Thr Ser Phe Met Met Thr Pro Tyr Val Val Thr Arg Tyr Tyr Arg 
            180                 185                 190         


Ala Pro Glu Val Ile Leu Gly Met Gly Tyr Lys Glu Asn Val Asp Ile 
        195                 200                 205             


Trp Ser Val Gly Cys Ile Met Gly Glu Met Val Arg His Lys Ile Leu 
    210                 215                 220                 


Phe Pro Gly Arg Asp Tyr Ile Asp Gln Trp Asn Lys Val Ile Glu Gln 
225                 230                 235                 240 


Leu Gly Thr Pro Cys Pro Glu Phe Met Lys Lys Leu Gln Pro Thr Val 
                245                 250                 255     


Arg Asn Tyr Val Glu Asn Arg Pro Lys Tyr Ala Gly Leu Thr Phe Pro 
            260                 265                 270         


Lys Leu Phe Pro Asp Ser Leu Phe Pro Ala Asp Ser Glu His Asn Lys 
        275                 280                 285             


Leu Lys Ala Ser Gln Ala Arg Asp Leu Leu Ser Lys Met Leu Val Ile 
    290                 295                 300                 


Asp Pro Ala Lys Arg Ile Ser Val Asp Asp Ala Leu Gln His Pro Tyr 
305                 310                 315                 320 


Ile Asn Val Trp Tyr Asp Pro Ala Glu Val Glu Ala Pro Pro Pro Gln 
                325                 330                 335     


Ile Tyr Asp Lys Gln Leu Asp Glu Arg Glu His Thr Ile Glu Glu Trp 
            340                 345                 350         


Lys Glu Leu Ile Tyr Lys Glu Val Met Asn Ser Glu Glu Lys Thr Lys 
        355                 360                 365             


Asn Gly Val Val Lys Gly Gln Pro Ser Pro Ser Gly Ala Ala Val Asn 
    370                 375                 380                 


Ser Ser Glu Ser Leu Pro Pro Ser Ser Ser Val Asn Asp Ile Ser Ser 
385                 390                 395                 400 


Met Ser Thr Asp Gln Thr Leu Ala Ser Asp Thr Asp Ser Ser Leu Glu 
                405                 410                 415     


Ala Ser Ala Gly Pro Leu Gly Cys Cys Arg 
            420                 425     


<210>  1350
<211>  268
<212>  PRT
<213>  Human

<400>  1350

Met Ala Val Asn Val Tyr Ser Thr Ser Val Thr Ser Asp Asn Leu Ser 
1               5                   10                  15      


Arg His Asp Met Leu Ala Trp Ile Asn Glu Ser Leu Gln Leu Asn Leu 
            20                  25                  30          


Thr Lys Ile Glu Gln Leu Cys Ser Gly Ala Ala Tyr Cys Gln Phe Met 
        35                  40                  45              


Asp Met Leu Phe Pro Gly Ser Ile Ala Leu Lys Lys Val Lys Phe Gln 
    50                  55                  60                  


Ala Lys Leu Glu His Glu Tyr Ile Gln Asn Phe Lys Ile Leu Gln Ala 
65                  70                  75                  80  


Gly Phe Lys Arg Met Gly Val Asp Lys Ile Ile Pro Val Asp Lys Leu 
                85                  90                  95      


Val Lys Gly Lys Phe Gln Asp Asn Phe Glu Phe Val Gln Trp Phe Lys 
            100                 105                 110         


Lys Phe Phe Asp Ala Asn Tyr Asp Gly Lys Asp Tyr Asp Pro Val Ala 
        115                 120                 125             


Ala Arg Gln Gly Gln Glu Thr Ala Val Ala Pro Ser Leu Val Ala Pro 
    130                 135                 140                 


Ala Leu Asn Lys Pro Lys Lys Pro Leu Thr Ser Ser Ser Ala Ala Pro 
145                 150                 155                 160 


Gln Arg Pro Ile Ser Thr Gln Arg Thr Ala Ala Ala Pro Lys Ala Gly 
                165                 170                 175     


Pro Gly Val Val Arg Lys Asn Pro Gly Val Gly Asn Gly Asp Asp Glu 
            180                 185                 190         


Ala Ala Glu Leu Met Gln Gln Val Asn Val Leu Lys Leu Thr Val Glu 
        195                 200                 205             


Asp Leu Glu Lys Glu Arg Asp Phe Tyr Phe Gly Lys Leu Arg Asn Ile 
    210                 215                 220                 


Glu Leu Ile Cys Gln Glu Asn Glu Gly Glu Asn Asp Pro Val Leu Gln 
225                 230                 235                 240 


Arg Ile Val Asp Ile Leu Tyr Ala Thr Asp Glu Gly Phe Val Ile Pro 
                245                 250                 255     


Asp Glu Gly Gly Pro Gln Glu Glu Gln Glu Glu Tyr 
            260                 265             


<210>  1351
<211>  352
<212>  PRT
<213>  Human

<400>  1351

Met Ala Glu Pro Arg Gln Glu Phe Glu Val Met Glu Asp His Ala Gly 
1               5                   10                  15      


Thr Tyr Gly Leu Gly Asp Arg Lys Asp Gln Gly Gly Tyr Thr Met His 
            20                  25                  30          


Gln Asp Gln Glu Gly Asp Thr Asp Ala Gly Leu Lys Ala Glu Glu Ala 
        35                  40                  45              


Gly Ile Gly Asp Thr Pro Ser Leu Glu Asp Glu Ala Ala Gly His Val 
    50                  55                  60                  


Thr Gln Ala Arg Met Val Ser Lys Ser Lys Asp Gly Thr Gly Ser Asp 
65                  70                  75                  80  


Asp Lys Lys Ala Lys Gly Ala Asp Gly Lys Thr Lys Ile Ala Thr Pro 
                85                  90                  95      


Arg Gly Ala Ala Pro Pro Gly Gln Lys Gly Gln Ala Asn Ala Thr Arg 
            100                 105                 110         


Ile Pro Ala Lys Thr Pro Pro Ala Pro Lys Thr Pro Pro Ser Ser Gly 
        115                 120                 125             


Glu Pro Pro Lys Ser Gly Asp Arg Ser Gly Tyr Ser Ser Pro Gly Ser 
    130                 135                 140                 


Pro Gly Thr Pro Gly Ser Arg Ser Arg Thr Pro Ser Leu Pro Thr Pro 
145                 150                 155                 160 


Pro Thr Arg Glu Pro Lys Lys Val Ala Val Val Arg Thr Pro Pro Lys 
                165                 170                 175     


Ser Pro Ser Ser Ala Lys Ser Arg Leu Gln Thr Ala Pro Val Pro Met 
            180                 185                 190         


Pro Asp Leu Lys Asn Val Lys Ser Lys Ile Gly Ser Thr Glu Asn Leu 
        195                 200                 205             


Lys His Gln Pro Gly Gly Gly Lys Val Gln Ile Val Tyr Lys Pro Val 
    210                 215                 220                 


Asp Leu Ser Lys Val Thr Ser Lys Cys Gly Ser Leu Gly Asn Ile His 
225                 230                 235                 240 


His Lys Pro Gly Gly Gly Gln Val Glu Val Lys Ser Glu Lys Leu Asp 
                245                 250                 255     


Phe Lys Asp Arg Val Gln Ser Lys Ile Gly Ser Leu Asp Asn Ile Thr 
            260                 265                 270         


His Val Pro Gly Gly Gly Asn Lys Lys Ile Glu Thr His Lys Leu Thr 
        275                 280                 285             


Phe Arg Glu Asn Ala Lys Ala Lys Thr Asp His Gly Ala Glu Ile Val 
    290                 295                 300                 


Tyr Lys Ser Pro Val Val Ser Gly Asp Thr Ser Pro Arg His Leu Ser 
305                 310                 315                 320 


Asn Val Ser Ser Thr Gly Ser Ile Asp Met Val Asp Ser Pro Gln Leu 
                325                 330                 335     


Ala Thr Leu Ala Asp Glu Val Ser Ala Ser Leu Ala Lys Gln Gly Leu 
            340                 345                 350         


<210>  1352
<211>  1798
<212>  PRT
<213>  Human

<400>  1352

Met Lys Arg Ser Arg Cys Arg Asp Arg Pro Gln Pro Pro Pro Pro Asp 
1               5                   10                  15      


Arg Arg Glu Asp Gly Val Gln Arg Ala Ala Glu Leu Ser Gln Ser Leu 
            20                  25                  30          


Pro Pro Arg Arg Arg Ala Pro Pro Gly Arg Gln Arg Leu Glu Glu Arg 
        35                  40                  45              


Thr Gly Pro Ala Gly Pro Glu Gly Lys Glu Gln Asp Val Val Thr Gly 
    50                  55                  60                  


Val Ser Pro Leu Leu Phe Arg Lys Leu Ser Asn Pro Asp Ile Phe Ser 
65                  70                  75                  80  


Ser Thr Gly Lys Val Lys Leu Gln Arg Gln Leu Ser Gln Asp Asp Cys 
                85                  90                  95      


Lys Leu Trp Arg Gly Asn Leu Ala Ser Ser Leu Ser Gly Lys Gln Leu 
            100                 105                 110         


Leu Pro Leu Ser Ser Ser Val His Ser Ser Val Gly Gln Val Thr Trp 
        115                 120                 125             


Gln Ser Ser Gly Glu Ala Ser Asn Leu Val Arg Met Arg Asn Gln Ser 
    130                 135                 140                 


Leu Gly Gln Ser Ala Pro Ser Leu Thr Ala Gly Leu Lys Glu Leu Ser 
145                 150                 155                 160 


Leu Pro Arg Arg Gly Ser Phe Cys Arg Thr Ser Asn Arg Lys Ser Leu 
                165                 170                 175     


Ile Val Thr Ser Ser Thr Ser Pro Thr Leu Pro Arg Pro His Ser Pro 
            180                 185                 190         


Leu His Gly His Thr Gly Asn Ser Pro Leu Asp Ser Pro Arg Asn Phe 
        195                 200                 205             


Ser Pro Asn Ala Pro Ala His Phe Ser Phe Val Pro Ala Arg Arg Thr 
    210                 215                 220                 


Asp Gly Arg Arg Trp Ser Leu Ala Ser Leu Pro Ser Ser Gly Tyr Gly 
225                 230                 235                 240 


Thr Asn Thr Pro Ser Ser Thr Val Ser Ser Ser Cys Ser Ser Gln Glu 
                245                 250                 255     


Lys Leu His Gln Leu Pro Phe Gln Pro Thr Ala Asp Glu Leu His Phe 
            260                 265                 270         


Leu Thr Lys His Phe Ser Thr Glu Ser Val Pro Asp Glu Glu Gly Arg 
        275                 280                 285             


Gln Ser Pro Ala Met Arg Pro Arg Ser Arg Ser Leu Ser Pro Gly Arg 
    290                 295                 300                 


Ser Pro Val Ser Phe Asp Ser Glu Ile Ile Met Met Asn His Val Tyr 
305                 310                 315                 320 


Lys Glu Arg Phe Pro Lys Ala Thr Ala Gln Met Glu Glu Arg Leu Ala 
                325                 330                 335     


Glu Phe Ile Ser Ser Asn Thr Pro Asp Ser Val Leu Pro Leu Ala Asp 
            340                 345                 350         


Gly Ala Leu Ser Phe Ile His His Gln Val Ile Glu Met Ala Arg Asp 
        355                 360                 365             


Cys Leu Asp Lys Ser Arg Ser Gly Leu Ile Thr Ser Gln Tyr Phe Tyr 
    370                 375                 380                 


Glu Leu Gln Asp Asn Leu Glu Lys Leu Leu Gln Asp Ala His Glu Arg 
385                 390                 395                 400 


Ser Glu Ser Ser Glu Val Ala Phe Val Met Gln Leu Val Lys Lys Leu 
                405                 410                 415     


Met Ile Ile Ile Ala Arg Pro Ala Arg Leu Leu Glu Cys Leu Glu Phe 
            420                 425                 430         


Asp Pro Glu Glu Phe Tyr His Leu Leu Glu Ala Ala Glu Gly His Ala 
        435                 440                 445             


Lys Glu Gly Gln Gly Ile Lys Cys Asp Ile Pro Arg Tyr Ile Val Ser 
    450                 455                 460                 


Gln Leu Gly Leu Thr Arg Asp Pro Leu Glu Glu Met Ala Gln Leu Ser 
465                 470                 475                 480 


Ser Cys Asp Ser Pro Asp Thr Pro Glu Thr Asp Asp Ser Ile Glu Gly 
                485                 490                 495     


His Gly Ala Ser Leu Pro Ser Lys Lys Thr Pro Ser Glu Glu Asp Phe 
            500                 505                 510         


Glu Thr Ile Lys Leu Ile Ser Asn Gly Ala Tyr Gly Ala Val Phe Leu 
        515                 520                 525             


Val Arg His Lys Ser Thr Arg Gln Arg Phe Ala Met Lys Lys Ile Asn 
    530                 535                 540                 


Lys Gln Asn Leu Ile Leu Arg Asn Gln Ile Gln Gln Ala Phe Val Glu 
545                 550                 555                 560 


Arg Asp Ile Leu Thr Phe Ala Glu Asn Pro Phe Val Val Ser Met Phe 
                565                 570                 575     


Cys Ser Phe Asp Thr Lys Arg His Leu Cys Met Val Met Glu Tyr Val 
            580                 585                 590         


Glu Gly Gly Asp Cys Ala Thr Leu Leu Lys Asn Ile Gly Ala Leu Pro 
        595                 600                 605             


Val Asp Met Val Arg Leu Tyr Phe Ala Glu Thr Val Leu Ala Leu Glu 
    610                 615                 620                 


Tyr Leu His Asn Tyr Gly Ile Val His Arg Asp Leu Lys Pro Asp Asn 
625                 630                 635                 640 


Leu Leu Ile Thr Ser Met Gly His Ile Lys Leu Thr Asp Phe Gly Leu 
                645                 650                 655     


Ser Lys Ile Gly Leu Met Ser Leu Thr Thr Asn Leu Tyr Glu Gly His 
            660                 665                 670         


Ile Glu Lys Asp Ala Arg Glu Phe Leu Asp Lys Gln Val Cys Gly Thr 
        675                 680                 685             


Pro Glu Tyr Ile Ala Pro Glu Val Ile Leu Arg Gln Gly Tyr Gly Lys 
    690                 695                 700                 


Pro Val Asp Trp Trp Ala Met Gly Ile Ile Leu Tyr Glu Phe Leu Val 
705                 710                 715                 720 


Gly Cys Val Pro Phe Phe Gly Asp Thr Pro Glu Glu Leu Phe Gly Gln 
                725                 730                 735     


Val Ile Ser Asp Glu Ile Val Trp Pro Glu Gly Asp Glu Ala Leu Pro 
            740                 745                 750         


Pro Asp Ala Gln Asp Leu Thr Ser Lys Leu Leu His Gln Asn Pro Leu 
        755                 760                 765             


Glu Arg Leu Gly Thr Gly Ser Ala Tyr Glu Val Lys Gln His Pro Phe 
    770                 775                 780                 


Phe Thr Gly Leu Asp Trp Thr Gly Leu Leu Arg Gln Lys Ala Glu Phe 
785                 790                 795                 800 


Ile Pro Gln Leu Glu Ser Glu Asp Asp Thr Ser Tyr Phe Asp Thr Arg 
                805                 810                 815     


Ser Glu Arg Tyr His His Met Asp Ser Glu Asp Glu Glu Glu Val Ser 
            820                 825                 830         


Glu Asp Gly Cys Leu Glu Ile Arg Gln Phe Ser Ser Cys Ser Pro Arg 
        835                 840                 845             


Phe Asn Lys Val Tyr Ser Ser Met Glu Arg Leu Ser Leu Leu Glu Glu 
    850                 855                 860                 


Arg Arg Thr Pro Pro Pro Thr Lys Arg Ser Leu Ser Glu Glu Lys Glu 
865                 870                 875                 880 


Asp His Ser Asp Gly Leu Ala Gly Leu Lys Gly Arg Asp Arg Ser Trp 
                885                 890                 895     


Val Ile Gly Ser Pro Glu Ile Leu Arg Lys Arg Leu Ser Val Ser Glu 
            900                 905                 910         


Ser Ser His Thr Glu Ser Asp Ser Ser Pro Pro Met Thr Val Arg Arg 
        915                 920                 925             


Arg Cys Ser Gly Leu Leu Asp Ala Pro Arg Phe Pro Glu Gly Pro Glu 
    930                 935                 940                 


Glu Ala Ser Ser Thr Leu Arg Arg Gln Pro Gln Glu Gly Ile Trp Val 
945                 950                 955                 960 


Leu Thr Pro Pro Ser Gly Glu Gly Val Ser Gly Pro Val Thr Glu His 
                965                 970                 975     


Ser Gly Glu Gln Arg Pro Lys Leu Asp Glu Glu Ala Val Gly Arg Ser 
            980                 985                 990         


Ser Gly Ser Ser Pro Ala Met Glu  Thr Arg Gly Arg Gly  Thr Ser Gln 
        995                 1000                 1005             


Leu Ala  Glu Gly Ala Thr Ala  Lys Ala Ile Ser Asp  Leu Ala Val 
    1010                 1015                 1020             


Arg Arg  Ala Arg His Arg Leu  Leu Ser Gly Asp Ser  Thr Glu Lys 
    1025                 1030                 1035             


Arg Thr  Ala Arg Pro Val Asn  Lys Val Ile Lys Ser  Ala Ser Ala 
    1040                 1045                 1050             


Thr Ala  Leu Ser Leu Leu Ile  Pro Ser Glu His His  Thr Cys Ser 
    1055                 1060                 1065             


Pro Leu  Ala Ser Pro Met Ser  Pro His Ser Gln Ser  Ser Asn Pro 
    1070                 1075                 1080             


Ser Ser  Arg Asp Ser Ser Pro  Ser Arg Asp Phe Leu  Pro Ala Leu 
    1085                 1090                 1095             


Gly Ser  Met Arg Pro Pro Ile  Ile Ile His Arg Ala  Gly Lys Lys 
    1100                 1105                 1110             


Tyr Gly  Phe Thr Leu Arg Ala  Ile Arg Val Tyr Met  Gly Asp Ser 
    1115                 1120                 1125             


Asp Val  Tyr Thr Val His His  Met Val Trp His Val  Glu Asp Gly 
    1130                 1135                 1140             


Gly Pro  Ala Ser Glu Ala Gly  Leu Arg Gln Gly Asp  Leu Ile Thr 
    1145                 1150                 1155             


His Val  Asn Gly Glu Pro Val  His Gly Leu Val His  Thr Glu Val 
    1160                 1165                 1170             


Val Glu  Leu Ile Leu Lys Ser  Gly Asn Lys Val Ala  Ile Ser Thr 
    1175                 1180                 1185             


Thr Pro  Leu Glu Asn Thr Ser  Ile Lys Val Gly Pro  Ala Arg Lys 
    1190                 1195                 1200             


Gly Ser  Tyr Lys Ala Lys Met  Ala Arg Arg Ser Lys  Arg Ser Arg 
    1205                 1210                 1215             


Gly Lys  Asp Gly Gln Glu Ser  Arg Lys Arg Ser Ser  Leu Phe Arg 
    1220                 1225                 1230             


Lys Ile  Thr Lys Gln Ala Ser  Leu Leu His Thr Ser  Arg Ser Leu 
    1235                 1240                 1245             


Ser Ser  Leu Asn Arg Ser Leu  Ser Ser Gly Glu Ser  Gly Pro Gly 
    1250                 1255                 1260             


Ser Pro  Thr His Ser His Ser  Leu Ser Pro Arg Ser  Pro Thr Gln 
    1265                 1270                 1275             


Gly Tyr  Arg Val Thr Pro Asp  Ala Val His Ser Val  Gly Gly Asn 
    1280                 1285                 1290             


Ser Ser  Gln Ser Ser Ser Pro  Ser Ser Ser Val Pro  Ser Ser Pro 
    1295                 1300                 1305             


Ala Gly  Ser Gly His Thr Arg  Pro Ser Ser Leu His  Gly Leu Ala 
    1310                 1315                 1320             


Pro Lys  Leu Gln Arg Gln Tyr  Arg Ser Pro Arg Arg  Lys Ser Ala 
    1325                 1330                 1335             


Gly Ser  Ile Pro Leu Ser Pro  Leu Ala His Thr Pro  Ser Pro Pro 
    1340                 1345                 1350             


Pro Pro  Thr Ala Ser Pro Gln  Arg Ser Pro Ser Pro  Leu Ser Gly 
    1355                 1360                 1365             


His Val  Ala Gln Ala Phe Pro  Thr Lys Leu His Leu  Ser Pro Pro 
    1370                 1375                 1380             


Leu Gly  Arg Gln Leu Ser Arg  Pro Lys Ser Ala Glu  Pro Pro Arg 
    1385                 1390                 1395             


Ser Pro  Leu Leu Lys Arg Val  Gln Ser Ala Glu Lys  Leu Ala Ala 
    1400                 1405                 1410             


Ala Leu  Ala Ala Ser Glu Lys  Lys Leu Ala Thr Ser  Arg Lys His 
    1415                 1420                 1425             


Ser Leu  Asp Leu Pro His Ser  Glu Leu Lys Lys Glu  Leu Pro Pro 
    1430                 1435                 1440             


Arg Glu  Val Ser Pro Leu Glu  Val Val Gly Ala Arg  Ser Val Leu 
    1445                 1450                 1455             


Ser Gly  Lys Gly Ala Leu Pro  Gly Lys Gly Val Leu  Gln Pro Ala 
    1460                 1465                 1470             


Pro Ser  Arg Ala Leu Gly Thr  Leu Arg Gln Asp Arg  Ala Glu Arg 
    1475                 1480                 1485             


Arg Glu  Ser Leu Gln Lys Gln  Glu Ala Ile Arg Glu  Val Asp Ser 
    1490                 1495                 1500             


Ser Glu  Asp Asp Thr Glu Glu  Gly Pro Glu Asn Ser  Gln Gly Ala 
    1505                 1510                 1515             


Gln Glu  Leu Ser Leu Ala Pro  His Pro Glu Val Ser  Gln Ser Val 
    1520                 1525                 1530             


Ala Pro  Lys Gly Ala Gly Glu  Ser Gly Glu Glu Asp  Pro Phe Pro 
    1535                 1540                 1545             


Ser Arg  Asp Pro Arg Ser Leu  Gly Pro Met Val Pro  Ser Leu Leu 
    1550                 1555                 1560             


Thr Gly  Ile Thr Leu Gly Pro  Pro Arg Met Glu Ser  Pro Ser Gly 
    1565                 1570                 1575             


Pro His  Arg Arg Leu Gly Ser  Pro Gln Ala Ile Glu  Glu Ala Ala 
    1580                 1585                 1590             


Ser Ser  Ser Ser Ala Gly Pro  Asn Leu Gly Gln Ser  Gly Ala Thr 
    1595                 1600                 1605             


Asp Pro  Ile Pro Pro Glu Gly  Cys Trp Lys Ala Gln  His Leu His 
    1610                 1615                 1620             


Thr Gln  Ala Leu Thr Ala Leu  Ser Pro Ser Thr Ser  Gly Leu Thr 
    1625                 1630                 1635             


Pro Thr  Ser Ser Cys Ser Pro  Pro Ser Ser Thr Ser  Gly Lys Leu 
    1640                 1645                 1650             


Ser Met  Trp Ser Trp Lys Ser  Leu Ile Glu Gly Pro  Asp Arg Ala 
    1655                 1660                 1665             


Ser Pro  Ser Arg Lys Ala Thr  Met Ala Gly Gly Leu  Ala Asn Leu 
    1670                 1675                 1680             


Gln Asp  Leu Glu Asn Thr Thr  Pro Ala Gln Pro Lys  Asn Leu Ser 
    1685                 1690                 1695             


Pro Arg  Glu Gln Gly Lys Thr  Gln Pro Pro Ser Ala  Pro Arg Leu 
    1700                 1705                 1710             


Ala His  Pro Ser Tyr Glu Asp  Pro Ser Gln Gly Trp  Leu Trp Glu 
    1715                 1720                 1725             


Ser Glu  Cys Ala Gln Ala Val  Lys Glu Asp Pro Ala  Leu Ser Ile 
    1730                 1735                 1740             


Thr Gln  Val Pro Asp Ala Ser  Gly Asp Arg Arg Gln  Asp Val Pro 
    1745                 1750                 1755             


Cys Arg  Gly Cys Pro Leu Thr  Gln Lys Ser Glu Pro  Ser Leu Arg 
    1760                 1765                 1770             


Arg Gly  Gln Glu Pro Gly Gly  His Gln Lys His Arg  Asp Leu Ala 
    1775                 1780                 1785             


Leu Val  Pro Asp Glu Leu Leu  Lys Gln Thr 
    1790                 1795             


<210>  1353
<211>  291
<212>  PRT
<213>  Human

<400>  1353

Met Glu Arg Lys Arg Trp Glu Cys Pro Ala Leu Pro Gln Gly Trp Glu 
1               5                   10                  15      


Arg Glu Glu Val Pro Arg Arg Ser Gly Leu Ser Ala Gly His Arg Asp 
            20                  25                  30          


Val Phe Tyr Tyr Ser Pro Ser Gly Lys Lys Phe Arg Ser Lys Pro Gln 
        35                  40                  45              


Leu Ala Arg Tyr Leu Gly Gly Ser Met Asp Leu Ser Thr Phe Asp Phe 
    50                  55                  60                  


Arg Thr Gly Lys Met Leu Met Ser Lys Met Asn Lys Ser Arg Gln Arg 
65                  70                  75                  80  


Val Arg Tyr Asp Ser Ser Asn Gln Val Lys Gly Lys Pro Asp Leu Asn 
                85                  90                  95      


Thr Ala Leu Pro Val Arg Gln Thr Ala Ser Ile Phe Lys Gln Pro Val 
            100                 105                 110         


Thr Lys Ile Thr Asn His Pro Ser Asn Lys Val Lys Ser Asp Pro Gln 
        115                 120                 125             


Lys Ala Val Asp Gln Pro Arg Gln Leu Phe Trp Glu Lys Lys Leu Ser 
    130                 135                 140                 


Gly Leu Asn Ala Phe Asp Ile Ala Glu Glu Leu Val Lys Thr Met Asp 
145                 150                 155                 160 


Leu Pro Lys Gly Leu Gln Gly Val Gly Pro Gly Cys Thr Asp Glu Thr 
                165                 170                 175     


Leu Leu Ser Ala Ile Ala Ser Ala Leu His Thr Ser Thr Met Pro Ile 
            180                 185                 190         


Thr Gly Gln Leu Ser Ala Ala Val Glu Lys Asn Pro Gly Val Trp Leu 
        195                 200                 205             


Asn Thr Thr Gln Pro Leu Cys Lys Ala Phe Met Val Thr Asp Glu Asp 
    210                 215                 220                 


Ile Arg Lys Gln Glu Glu Leu Val Gln Gln Val Arg Lys Arg Leu Glu 
225                 230                 235                 240 


Glu Ala Leu Met Ala Asp Met Leu Ala His Val Glu Glu Leu Ala Arg 
                245                 250                 255     


Asp Gly Glu Ala Pro Leu Asp Lys Ala Cys Ala Glu Asp Asp Asp Glu 
            260                 265                 270         


Glu Asp Glu Glu Glu Glu Glu Glu Glu Pro Asp Pro Asp Pro Glu Met 
        275                 280                 285             


Glu His Val 
    290     


<210>  1354
<211>  725
<212>  PRT
<213>  Human

<400>  1354

Met Ala Ala Ala Ser Ala Val Ser Val Leu Leu Val Ala Ala Glu Arg 
1               5                   10                  15      


Asn Arg Trp His Arg Leu Pro Ser Leu Leu Leu Pro Pro Arg Thr Trp 
            20                  25                  30          


Val Trp Arg Gln Arg Thr Met Lys Tyr Thr Thr Ala Thr Gly Arg Asn 
        35                  40                  45              


Ile Thr Lys Val Leu Ile Ala Asn Arg Gly Glu Ile Ala Cys Arg Val 
    50                  55                  60                  


Met Arg Thr Ala Lys Lys Leu Gly Val Gln Thr Val Ala Val Tyr Ser 
65                  70                  75                  80  


Glu Ala Asp Arg Asn Ser Met His Val Asp Met Ala Asp Glu Ala Tyr 
                85                  90                  95      


Ser Ile Gly Pro Ala Pro Ser Gln Gln Ser Tyr Leu Ser Met Glu Lys 
            100                 105                 110         


Ile Ile Gln Val Ala Lys Thr Ser Ala Ala Gln Ala Ile His Pro Gly 
        115                 120                 125             


Cys Gly Phe Leu Ser Glu Asn Met Glu Phe Ala Glu Leu Cys Lys Gln 
    130                 135                 140                 


Glu Gly Ile Ile Phe Ile Gly Pro Pro Pro Ser Ala Ile Arg Asp Met 
145                 150                 155                 160 


Gly Ile Lys Ser Thr Ser Lys Ser Ile Met Ala Ala Ala Gly Val Pro 
                165                 170                 175     


Val Val Glu Gly Tyr His Gly Glu Asp Gln Ser Asp Gln Cys Leu Lys 
            180                 185                 190         


Glu His Ala Arg Arg Ile Gly Tyr Pro Val Met Ile Lys Ala Val Arg 
        195                 200                 205             


Gly Gly Gly Gly Lys Gly Met Arg Ile Val Arg Ser Glu Gln Glu Phe 
    210                 215                 220                 


Gln Glu Gln Leu Glu Ser Ala Arg Arg Glu Ala Lys Lys Ser Phe Asn 
225                 230                 235                 240 


Asp Asp Ala Met Leu Ile Glu Lys Phe Val Asp Thr Pro Arg His Val 
                245                 250                 255     


Glu Val Gln Val Phe Gly Asp His His Gly Asn Ala Val Tyr Leu Phe 
            260                 265                 270         


Glu Arg Asp Cys Ser Val Gln Arg Arg His Gln Lys Ile Ile Glu Glu 
        275                 280                 285             


Ala Pro Ala Pro Gly Ile Lys Ser Glu Val Arg Lys Lys Leu Gly Glu 
    290                 295                 300                 


Ala Ala Val Arg Ala Ala Lys Ala Val Asn Tyr Val Gly Ala Gly Thr 
305                 310                 315                 320 


Val Glu Phe Ile Met Asp Ser Lys His Asn Phe Cys Phe Met Glu Met 
                325                 330                 335     


Asn Thr Arg Leu Gln Val Glu His Pro Val Thr Glu Met Ile Thr Gly 
            340                 345                 350         


Thr Asp Leu Val Glu Trp Gln Leu Arg Ile Ala Ala Gly Glu Lys Ile 
        355                 360                 365             


Pro Leu Ser Gln Glu Glu Ile Thr Leu Gln Gly His Ala Phe Glu Ala 
    370                 375                 380                 


Arg Ile Tyr Ala Glu Asp Pro Ser Asn Asn Phe Met Pro Val Ala Gly 
385                 390                 395                 400 


Pro Leu Val His Leu Ser Thr Pro Arg Ala Asp Pro Ser Thr Arg Ile 
                405                 410                 415     


Glu Thr Gly Val Arg Gln Gly Asp Glu Val Ser Val His Tyr Asp Pro 
            420                 425                 430         


Met Ile Ala Lys Leu Val Val Trp Ala Ala Asp Arg Gln Ala Ala Leu 
        435                 440                 445             


Thr Lys Leu Arg Tyr Ser Leu Arg Gln Tyr Asn Ile Val Gly Leu His 
    450                 455                 460                 


Thr Asn Ile Asp Phe Leu Leu Asn Leu Ser Gly His Pro Glu Phe Glu 
465                 470                 475                 480 


Ala Gly Asn Val His Thr Asp Phe Ile Pro Gln His His Lys Gln Leu 
                485                 490                 495     


Leu Leu Ser Arg Lys Ala Ala Ala Lys Glu Ser Leu Cys Gln Ala Ala 
            500                 505                 510         


Leu Gly Leu Ile Leu Lys Glu Lys Ala Met Thr Asp Thr Phe Thr Leu 
        515                 520                 525             


Gln Ala His Asp Gln Phe Ser Pro Phe Ser Ser Ser Ser Gly Arg Arg 
    530                 535                 540                 


Leu Asn Ile Ser Tyr Thr Arg Asn Met Thr Leu Lys Asp Gly Lys Asn 
545                 550                 555                 560 


Asn Val Ala Ile Ala Val Thr Tyr Asn His Asp Gly Ser Tyr Ser Met 
                565                 570                 575     


Gln Ile Glu Asp Lys Thr Phe Gln Val Leu Gly Asn Leu Tyr Ser Glu 
            580                 585                 590         


Gly Asp Cys Thr Tyr Leu Lys Cys Ser Val Asn Gly Val Ala Ser Lys 
        595                 600                 605             


Ala Lys Leu Ile Ile Leu Glu Asn Thr Ile Tyr Leu Phe Ser Lys Glu 
    610                 615                 620                 


Gly Ser Ile Glu Ile Asp Ile Pro Val Pro Lys Tyr Leu Ser Ser Val 
625                 630                 635                 640 


Ser Ser Gln Glu Thr Gln Gly Gly Pro Leu Ala Pro Met Thr Gly Thr 
                645                 650                 655     


Ile Glu Lys Val Phe Val Lys Ala Gly Asp Lys Val Lys Ala Gly Asp 
            660                 665                 670         


Ser Leu Met Val Met Ile Ala Met Lys Met Glu His Thr Ile Lys Ser 
        675                 680                 685             


Pro Lys Asp Gly Thr Val Lys Lys Val Phe Tyr Arg Glu Gly Ala Gln 
    690                 695                 700                 


Ala Asn Arg His Thr Pro Leu Val Glu Phe Glu Glu Glu Glu Ser Asp 
705                 710                 715                 720 


Lys Arg Glu Ser Glu 
                725 


<210>  1355
<211>  1541
<212>  PRT
<213>  Human

<400>  1355

Met Ser Phe Leu Glu Glu Ala Arg Ala Ala Gly Arg Ala Val Val Leu 
1               5                   10                  15      


Ala Leu Val Leu Leu Leu Leu Pro Ala Val Pro Val Gly Ala Ser Val 
            20                  25                  30          


Pro Pro Arg Pro Leu Leu Pro Leu Gln Pro Gly Met Pro His Val Cys 
        35                  40                  45              


Ala Glu Gln Glu Leu Thr Leu Val Gly Arg Arg Gln Pro Cys Val Gln 
    50                  55                  60                  


Ala Leu Ser His Thr Val Pro Val Trp Lys Ala Gly Cys Gly Trp Gln 
65                  70                  75                  80  


Ala Trp Cys Val Gly His Glu Arg Arg Thr Val Tyr Tyr Met Gly Tyr 
                85                  90                  95      


Arg Gln Val Tyr Thr Thr Glu Ala Arg Thr Val Leu Arg Cys Cys Arg 
            100                 105                 110         


Gly Trp Met Gln Gln Pro Asp Glu Glu Gly Cys Leu Ser Ala Glu Cys 
        115                 120                 125             


Ser Ala Ser Leu Cys Phe His Gly Gly Arg Cys Val Pro Gly Ser Ala 
    130                 135                 140                 


Gln Pro Cys His Cys Pro Pro Gly Phe Gln Gly Pro Arg Cys Gln Tyr 
145                 150                 155                 160 


Asp Val Asp Glu Cys Arg Thr His Asn Gly Gly Cys Gln His Arg Cys 
                165                 170                 175     


Val Asn Thr Pro Gly Ser Tyr Leu Cys Glu Cys Lys Pro Gly Phe Arg 
            180                 185                 190         


Leu His Thr Asp Ser Arg Thr Cys Leu Ala Ile Asn Ser Cys Ala Leu 
        195                 200                 205             


Gly Asn Gly Gly Cys Gln His His Cys Val Gln Leu Thr Ile Thr Arg 
    210                 215                 220                 


His Arg Cys Gln Cys Arg Pro Gly Phe Gln Leu Gln Glu Asp Gly Arg 
225                 230                 235                 240 


His Cys Val Arg Arg Ser Pro Cys Ala Asn Arg Asn Gly Ser Cys Met 
                245                 250                 255     


His Arg Cys Gln Val Val Arg Gly Leu Ala Arg Cys Glu Cys His Val 
            260                 265                 270         


Gly Tyr Gln Leu Ala Ala Asp Gly Lys Ala Cys Glu Asp Val Asp Glu 
        275                 280                 285             


Cys Ala Ala Gly Leu Ala Gln Cys Ala His Gly Cys Leu Asn Thr Gln 
    290                 295                 300                 


Gly Ser Phe Lys Cys Val Cys His Ala Gly Tyr Glu Leu Gly Ala Asp 
305                 310                 315                 320 


Gly Arg Gln Cys Tyr Arg Ile Glu Met Glu Ile Val Asn Ser Cys Glu 
                325                 330                 335     


Ala Asn Asn Gly Gly Cys Ser His Gly Cys Ser His Thr Ser Ala Gly 
            340                 345                 350         


Pro Leu Cys Thr Cys Pro Arg Gly Tyr Glu Leu Asp Thr Asp Gln Arg 
        355                 360                 365             


Thr Cys Ile Asp Val Asp Asp Cys Ala Asp Ser Pro Cys Cys Gln Gln 
    370                 375                 380                 


Val Cys Thr Asn Asn Pro Gly Gly Tyr Glu Cys Gly Cys Tyr Ala Gly 
385                 390                 395                 400 


Tyr Arg Leu Ser Ala Asp Gly Cys Gly Cys Glu Asp Val Asp Glu Cys 
                405                 410                 415     


Ala Ser Ser Arg Gly Gly Cys Glu His His Cys Thr Asn Leu Ala Gly 
            420                 425                 430         


Ser Phe Gln Cys Ser Cys Glu Ala Gly Tyr Arg Leu His Glu Asp Arg 
        435                 440                 445             


Arg Gly Cys Ser Pro Leu Glu Glu Pro Met Val Asp Leu Asp Gly Glu 
    450                 455                 460                 


Leu Pro Phe Val Arg Pro Leu Pro His Ile Ala Val Leu Gln Asp Glu 
465                 470                 475                 480 


Leu Pro Gln Leu Phe Gln Asp Asp Asp Val Gly Ala Asp Glu Glu Glu 
                485                 490                 495     


Ala Glu Leu Arg Gly Glu His Thr Leu Thr Glu Lys Phe Val Cys Leu 
            500                 505                 510         


Asp Asp Ser Phe Gly His Asp Cys Ser Leu Thr Cys Asp Asp Cys Arg 
        515                 520                 525             


Asn Gly Gly Thr Cys Leu Leu Gly Leu Asp Gly Cys Asp Cys Pro Glu 
    530                 535                 540                 


Gly Trp Thr Gly Leu Ile Cys Asn Glu Thr Cys Pro Pro Asp Thr Phe 
545                 550                 555                 560 


Gly Lys Asn Cys Ser Phe Ser Cys Ser Cys Gln Asn Gly Gly Thr Cys 
                565                 570                 575     


Asp Ser Val Thr Gly Ala Cys Arg Cys Pro Pro Gly Val Ser Gly Thr 
            580                 585                 590         


Asn Cys Glu Asp Gly Cys Pro Lys Gly Tyr Tyr Gly Lys His Cys Arg 
        595                 600                 605             


Lys Lys Cys Asn Cys Ala Asn Arg Gly Arg Cys His Arg Leu Tyr Gly 
    610                 615                 620                 


Ala Cys Leu Cys Asp Pro Gly Leu Tyr Gly Arg Phe Cys His Leu Thr 
625                 630                 635                 640 


Cys Pro Pro Trp Ala Phe Gly Pro Gly Cys Ser Glu Glu Cys Gln Cys 
                645                 650                 655     


Val Gln Pro His Thr Gln Ser Cys Asp Lys Arg Asp Gly Ser Cys Ser 
            660                 665                 670         


Cys Lys Ala Gly Phe Arg Gly Glu Arg Cys Gln Ala Glu Cys Glu Leu 
        675                 680                 685             


Gly Tyr Phe Gly Pro Gly Cys Trp Gln Ala Cys Thr Cys Pro Val Gly 
    690                 695                 700                 


Val Ala Cys Asp Ser Val Ser Gly Glu Cys Gly Lys Arg Cys Pro Ala 
705                 710                 715                 720 


Gly Phe Gln Gly Glu Asp Cys Gly Gln Glu Cys Pro Val Gly Thr Phe 
                725                 730                 735     


Gly Val Asn Cys Ser Ser Ser Cys Ser Cys Gly Gly Ala Pro Cys His 
            740                 745                 750         


Gly Val Thr Gly Gln Cys Arg Cys Pro Pro Gly Arg Thr Gly Glu Asp 
        755                 760                 765             


Cys Glu Ala Asp Cys Pro Glu Gly Arg Trp Gly Leu Gly Cys Gln Glu 
    770                 775                 780                 


Ile Cys Pro Ala Cys Gln His Ala Ala Arg Cys Asp Pro Glu Thr Gly 
785                 790                 795                 800 


Ala Cys Leu Cys Leu Pro Gly Phe Val Gly Ser Arg Cys Gln Asp Val 
                805                 810                 815     


Cys Pro Ala Gly Trp Tyr Gly Pro Ser Cys Gln Thr Arg Cys Ser Cys 
            820                 825                 830         


Ala Asn Asp Gly His Cys His Pro Ala Thr Gly His Cys Ser Cys Ala 
        835                 840                 845             


Pro Gly Trp Thr Gly Phe Ser Cys Gln Arg Ala Cys Asp Thr Gly His 
    850                 855                 860                 


Trp Gly Pro Asp Cys Ser His Pro Cys Asn Cys Ser Ala Gly His Gly 
865                 870                 875                 880 


Ser Cys Asp Ala Ile Ser Gly Leu Cys Leu Cys Glu Ala Gly Tyr Val 
                885                 890                 895     


Gly Pro Arg Cys Glu Gln Gln Cys Pro Gln Gly His Phe Gly Pro Gly 
            900                 905                 910         


Cys Glu Gln Arg Cys Gln Cys Gln His Gly Ala Ala Cys Asp His Val 
        915                 920                 925             


Ser Gly Ala Cys Thr Cys Pro Ala Gly Trp Arg Gly Thr Phe Cys Glu 
    930                 935                 940                 


His Ala Cys Pro Ala Gly Phe Phe Gly Leu Asp Cys Arg Ser Ala Cys 
945                 950                 955                 960 


Asn Cys Thr Ala Gly Ala Ala Cys Asp Ala Val Asn Gly Ser Cys Leu 
                965                 970                 975     


Cys Pro Ala Gly Arg Arg Gly Pro Arg Cys Ala Glu Thr Cys Pro Ala 
            980                 985                 990         


His Thr Tyr Gly His Asn Cys Ser  Gln Ala Cys Ala Cys  Phe Asn Gly 
        995                 1000                 1005             


Ala Ser  Cys Asp Pro Val His  Gly Gln Cys His Cys  Ala Pro Gly 
    1010                 1015                 1020             


Trp Met  Gly Pro Ser Cys Leu  Gln Ala Cys Pro Ala  Gly Leu Tyr 
    1025                 1030                 1035             


Gly Asp  Asn Cys Arg His Ser  Cys Leu Cys Gln Asn  Gly Gly Thr 
    1040                 1045                 1050             


Cys Asp  Pro Val Ser Gly His  Cys Ala Cys Pro Glu  Gly Trp Ala 
    1055                 1060                 1065             


Gly Leu  Ala Cys Glu Lys Glu  Cys Leu Pro Arg Asp  Val Arg Ala 
    1070                 1075                 1080             


Gly Cys  Arg His Ser Gly Gly  Cys Leu Asn Gly Gly  Leu Cys Asp 
    1085                 1090                 1095             


Pro His  Thr Gly Arg Cys Leu  Cys Pro Ala Gly Trp  Thr Gly Asp 
    1100                 1105                 1110             


Lys Cys  Gln Ser Pro Cys Leu  Arg Gly Trp Phe Gly  Glu Ala Cys 
    1115                 1120                 1125             


Ala Gln  Arg Cys Ser Cys Pro  Pro Gly Ala Ala Cys  His His Val 
    1130                 1135                 1140             


Thr Gly  Ala Cys Arg Cys Pro  Pro Gly Phe Thr Gly  Ser Gly Cys 
    1145                 1150                 1155             


Glu Gln  Ala Cys Pro Pro Gly  Ser Phe Gly Glu Asp  Cys Ala Gln 
    1160                 1165                 1170             


Met Cys  Gln Cys Pro Gly Glu  Asn Pro Ala Cys His  Pro Ala Thr 
    1175                 1180                 1185             


Gly Thr  Cys Ser Cys Ala Ala  Gly Tyr His Gly Pro  Ser Cys Gln 
    1190                 1195                 1200             


Gln Arg  Cys Pro Pro Gly Arg  Tyr Gly Pro Gly Cys  Glu Gln Leu 
    1205                 1210                 1215             


Cys Gly  Cys Leu Asn Gly Gly  Ser Cys Asp Ala Ala  Thr Gly Ala 
    1220                 1225                 1230             


Cys Arg  Cys Pro Thr Gly Phe  Leu Gly Thr Asp Cys  Asn Leu Thr 
    1235                 1240                 1245             


Cys Pro  Gln Gly Arg Phe Gly  Pro Asn Cys Thr His  Val Cys Gly 
    1250                 1255                 1260             


Cys Gly  Gln Gly Ala Ala Cys  Asp Pro Val Thr Gly  Thr Cys Leu 
    1265                 1270                 1275             


Cys Pro  Pro Gly Arg Ala Gly  Val Arg Cys Glu Arg  Gly Cys Pro 
    1280                 1285                 1290             


Gln Asn  Arg Phe Gly Val Gly  Cys Glu His Thr Cys  Ser Cys Arg 
    1295                 1300                 1305             


Asn Gly  Gly Leu Cys His Ala  Ser Asn Gly Ser Cys  Ser Cys Gly 
    1310                 1315                 1320             


Leu Gly  Trp Thr Gly Arg His  Cys Glu Leu Ala Cys  Pro Pro Gly 
    1325                 1330                 1335             


Arg Tyr  Gly Ala Ala Cys His  Leu Glu Cys Ser Cys  His Asn Asn 
    1340                 1345                 1350             


Ser Thr  Cys Glu Pro Ala Thr  Gly Thr Cys Arg Cys  Gly Pro Gly 
    1355                 1360                 1365             


Phe Tyr  Gly Gln Ala Cys Glu  His Pro Cys Pro Pro  Gly Phe His 
    1370                 1375                 1380             


Gly Ala  Gly Cys Gln Gly Leu  Cys Trp Cys Gln His  Gly Ala Pro 
    1385                 1390                 1395             


Cys Asp  Pro Ile Ser Gly Arg  Cys Leu Cys Pro Ala  Gly Phe His 
    1400                 1405                 1410             


Gly His  Phe Cys Glu Arg Gly  Cys Glu Pro Gly Ser  Phe Gly Glu 
    1415                 1420                 1425             


Gly Cys  His Gln Arg Cys Asp  Cys Asp Gly Gly Ala  Pro Cys Asp 
    1430                 1435                 1440             


Pro Val  Thr Gly Leu Cys Leu  Cys Pro Pro Gly Arg  Ser Gly Ala 
    1445                 1450                 1455             


Thr Cys  Asn Leu Asp Cys Arg  Arg Gly Gln Phe Gly  Pro Ser Cys 
    1460                 1465                 1470             


Thr Leu  His Cys Asp Cys Gly  Gly Gly Ala Asp Cys  Asp Pro Val 
    1475                 1480                 1485             


Ser Gly  Gln Cys His Cys Val  Asp Gly Tyr Met Gly  Pro Thr Cys 
    1490                 1495                 1500             


Arg Glu  Gly Gly Pro Leu Arg  Leu Pro Glu Asn Pro  Ser Leu Ala 
    1505                 1510                 1515             


Gln Gly  Ser Ala Gly Thr Leu  Pro Ala Ser Ser Arg  Pro Thr Ser 
    1520                 1525                 1530             


Arg Ser  Gly Gly Pro Ala Arg  His 
    1535                 1540     


<210>  1356
<211>  1093
<212>  PRT
<213>  Human

<400>  1356

Met Lys Glu Met Val Gly Gly Cys Cys Val Cys Ser Asp Glu Arg Gly 
1               5                   10                  15      


Trp Ala Glu Asn Pro Leu Val Tyr Cys Asp Gly His Ala Cys Ser Val 
            20                  25                  30          


Ala Val His Gln Ala Cys Tyr Gly Ile Val Gln Val Pro Thr Gly Pro 
        35                  40                  45              


Trp Phe Cys Arg Lys Cys Glu Ser Gln Glu Arg Ala Ala Arg Val Arg 
    50                  55                  60                  


Cys Glu Leu Cys Pro His Lys Asp Gly Ala Leu Lys Arg Thr Asp Asn 
65                  70                  75                  80  


Gly Gly Trp Ala His Val Val Cys Ala Leu Tyr Ile Pro Glu Val Gln 
                85                  90                  95      


Phe Ala Asn Val Leu Thr Met Glu Pro Ile Val Leu Gln Tyr Val Pro 
            100                 105                 110         


His Asp Arg Phe Asn Lys Thr Cys Tyr Ile Cys Glu Glu Gln Gly Arg 
        115                 120                 125             


Glu Ser Lys Ala Ala Ser Gly Ala Cys Met Thr Cys Asn Arg His Gly 
    130                 135                 140                 


Cys Arg Gln Ala Phe His Val Thr Cys Ala Gln Met Ala Gly Leu Leu 
145                 150                 155                 160 


Cys Glu Glu Glu Val Leu Glu Val Asp Asn Val Lys Tyr Cys Gly Tyr 
                165                 170                 175     


Cys Lys Tyr His Phe Ser Lys Met Lys Thr Ser Arg His Ser Ser Gly 
            180                 185                 190         


Gly Gly Gly Gly Gly Ala Gly Gly Gly Gly Gly Ser Met Gly Gly Gly 
        195                 200                 205             


Gly Ser Gly Phe Ile Ser Gly Arg Arg Ser Arg Ser Ala Ser Pro Ser 
    210                 215                 220                 


Thr Gln Gln Glu Lys His Pro Thr His His Glu Arg Gly Gln Lys Lys 
225                 230                 235                 240 


Ser Arg Lys Asp Lys Glu Arg Leu Lys Gln Lys His Lys Lys Arg Pro 
                245                 250                 255     


Glu Ser Pro Pro Ser Ile Leu Thr Pro Pro Val Val Pro Thr Ala Asp 
            260                 265                 270         


Lys Val Ser Ser Ser Ala Ser Ser Ser Ser His His Glu Ala Ser Thr 
        275                 280                 285             


Gln Glu Thr Ser Glu Ser Ser Arg Glu Ser Lys Gly Lys Lys Ser Ser 
    290                 295                 300                 


Ser His Ser Leu Ser His Lys Gly Lys Lys Leu Ser Ser Gly Lys Gly 
305                 310                 315                 320 


Val Ser Ser Phe Thr Ser Ala Ser Ser Ser Ser Ser Ser Ser Ser Ser 
                325                 330                 335     


Ser Ser Gly Gly Pro Phe Gln Pro Ala Val Ser Ser Leu Gln Ser Ser 
            340                 345                 350         


Pro Asp Phe Ser Ala Phe Pro Lys Leu Glu Gln Pro Glu Glu Asp Lys 
        355                 360                 365             


Tyr Ser Lys Pro Thr Ala Pro Ala Pro Ser Ala Pro Pro Ser Pro Ser 
    370                 375                 380                 


Ala Pro Glu Pro Pro Lys Ala Asp Leu Phe Glu Gln Lys Val Val Phe 
385                 390                 395                 400 


Ser Gly Phe Gly Pro Ile Met Arg Phe Ser Thr Thr Thr Ser Ser Ser 
                405                 410                 415     


Gly Arg Ala Arg Ala Pro Ser Pro Gly Asp Tyr Lys Ser Pro His Val 
            420                 425                 430         


Thr Gly Ser Gly Ala Ser Ala Gly Thr His Lys Arg Met Pro Ala Leu 
        435                 440                 445             


Ser Ala Thr Pro Val Pro Ala Asp Glu Thr Pro Glu Thr Gly Leu Lys 
    450                 455                 460                 


Glu Lys Lys His Lys Ala Ser Lys Arg Ser Arg His Gly Pro Gly Arg 
465                 470                 475                 480 


Pro Lys Gly Ser Arg Asn Lys Glu Gly Thr Gly Gly Pro Ala Ala Pro 
                485                 490                 495     


Ser Leu Pro Ser Ala Gln Leu Ala Gly Phe Thr Ala Thr Ala Ala Ser 
            500                 505                 510         


Pro Phe Ser Gly Gly Ser Leu Val Ser Ser Gly Leu Gly Gly Leu Ser 
        515                 520                 525             


Ser Arg Thr Phe Gly Pro Ser Gly Ser Leu Pro Ser Leu Ser Leu Glu 
    530                 535                 540                 


Ser Pro Leu Leu Gly Ala Gly Ile Tyr Thr Ser Asn Lys Asp Pro Ile 
545                 550                 555                 560 


Ser His Ser Gly Gly Met Leu Arg Ala Val Cys Ser Thr Pro Leu Ser 
                565                 570                 575     


Ser Ser Leu Leu Gly Pro Pro Gly Thr Ser Ala Leu Pro Arg Leu Ser 
            580                 585                 590         


Arg Ser Pro Phe Thr Ser Thr Leu Pro Ser Ser Ser Ala Ser Ile Ser 
        595                 600                 605             


Thr Thr Gln Val Phe Ser Leu Ala Gly Ser Thr Phe Ser Leu Pro Ser 
    610                 615                 620                 


Thr His Ile Phe Gly Thr Pro Met Gly Ala Val Asn Pro Leu Leu Ser 
625                 630                 635                 640 


Gln Ala Glu Ser Ser His Thr Glu Pro Asp Leu Glu Asp Cys Ser Phe 
                645                 650                 655     


Arg Cys Arg Gly Thr Ser Pro Gln Glu Ser Leu Ser Ser Met Ser Pro 
            660                 665                 670         


Ile Ser Ser Leu Pro Ala Leu Phe Asp Gln Thr Ala Ser Ala Pro Cys 
        675                 680                 685             


Gly Gly Gly Gln Leu Asp Pro Ala Ala Pro Gly Thr Thr Asn Met Glu 
    690                 695                 700                 


Gln Leu Leu Glu Lys Gln Gly Asp Gly Glu Ala Gly Val Asn Ile Val 
705                 710                 715                 720 


Glu Met Leu Lys Ala Leu His Ala Leu Gln Lys Glu Asn Gln Arg Leu 
                725                 730                 735     


Gln Glu Gln Ile Leu Ser Leu Thr Ala Lys Lys Glu Arg Leu Gln Ile 
            740                 745                 750         


Leu Asn Val Gln Leu Ser Val Pro Phe Pro Ala Leu Pro Ala Ala Leu 
        755                 760                 765             


Pro Ala Ala Asn Gly Pro Val Pro Gly Pro Tyr Gly Leu Pro Pro Gln 
    770                 775                 780                 


Ala Gly Ser Ser Asp Ser Leu Ser Thr Ser Lys Ser Pro Pro Gly Lys 
785                 790                 795                 800 


Ser Ser Leu Gly Leu Asp Asn Ser Leu Ser Thr Ser Ser Glu Asp Pro 
                805                 810                 815     


His Ser Gly Cys Pro Ser Arg Ser Ser Ser Ser Leu Ser Phe His Ser 
            820                 825                 830         


Thr Pro Pro Pro Leu Pro Leu Leu Gln Gln Ser Pro Ala Thr Leu Pro 
        835                 840                 845             


Leu Ala Leu Pro Gly Ala Pro Ala Pro Leu Pro Pro Gln Pro Gln Asn 
    850                 855                 860                 


Gly Leu Gly Arg Ala Pro Gly Ala Ala Gly Leu Gly Ala Met Pro Met 
865                 870                 875                 880 


Ala Glu Gly Leu Leu Gly Gly Leu Ala Gly Ser Gly Gly Leu Pro Leu 
                885                 890                 895     


Asn Gly Leu Leu Gly Gly Leu Asn Gly Ala Ala Ala Pro Asn Pro Ala 
            900                 905                 910         


Ser Leu Ser Gln Ala Gly Gly Ala Pro Thr Leu Gln Leu Pro Gly Cys 
        915                 920                 925             


Leu Asn Ser Leu Thr Glu Gln Gln Arg His Leu Leu Gln Gln Gln Glu 
    930                 935                 940                 


Gln Gln Leu Gln Gln Leu Gln Gln Leu Leu Ala Ser Pro Gln Leu Thr 
945                 950                 955                 960 


Pro Glu His Gln Thr Val Val Tyr Gln Met Ile Gln Gln Ile Gln Gln 
                965                 970                 975     


Lys Arg Glu Leu Gln Arg Leu Gln Met Ala Gly Gly Ser Gln Leu Pro 
            980                 985                 990         


Met Ala Ser Leu Leu Ala Gly Ser  Ser Thr Pro Leu Leu  Ser Ala Gly 
        995                 1000                 1005             


Thr Pro  Gly Leu Leu Pro Thr  Ala Ser Ala Pro Pro  Leu Leu Pro 
    1010                 1015                 1020             


Ala Gly  Ala Leu Val Ala Pro  Ser Leu Gly Asn Asn  Thr Ser Leu 
    1025                 1030                 1035             


Met Ala  Ala Ala Ala Ala Ala  Ala Ala Val Ala Ala  Ala Gly Gly 
    1040                 1045                 1050             


Pro Pro  Val Leu Thr Ala Gln  Thr Asn Pro Phe Leu  Ser Leu Ser 
    1055                 1060                 1065             


Gly Ala  Glu Gly Ser Gly Gly  Gly Pro Lys Gly Gly  Thr Ala Asp 
    1070                 1075                 1080             


Lys Gly  Ala Ser Ala Asn Gln  Glu Lys Gly 
    1085                 1090             


<210>  1357
<211>  160
<212>  PRT
<213>  Human

<400>  1357

Met Ala Ala Glu Arg Lys Thr Arg Leu Ser Lys Asn Leu Leu Arg Met 
1               5                   10                  15      


Lys Phe Met Gln Arg Gly Leu Asp Ser Glu Thr Lys Lys Gln Leu Glu 
            20                  25                  30          


Glu Glu Glu Lys Lys Ile Ile Ser Glu Glu His Trp Tyr Leu Asp Leu 
        35                  40                  45              


Pro Glu Leu Lys Glu Lys Glu Ser Phe Ile Ile Glu Glu Gln Ser Phe 
    50                  55                  60                  


Leu Leu Cys Glu Asp Leu Leu Tyr Gly Arg Met Ser Phe Arg Gly Phe 
65                  70                  75                  80  


Asn Pro Glu Val Glu Lys Leu Met Leu Gln Met Asn Ala Lys His Lys 
                85                  90                  95      


Ala Glu Glu Val Glu Asp Glu Thr Val Glu Leu Asp Val Ser Asp Glu 
            100                 105                 110         


Glu Met Ala Arg Arg Tyr Glu Thr Leu Val Gly Thr Ile Gly Lys Lys 
        115                 120                 125             


Phe Ala Arg Lys Arg Asp His Ala Asn Tyr Glu Glu Asp Glu Asn Gly 
    130                 135                 140                 


Asp Ile Thr Pro Ile Lys Ala Lys Lys Met Phe Leu Lys Pro Gln Asp 
145                 150                 155                 160 


<210>  1358
<211>  395
<212>  PRT
<213>  Human

<400>  1358

Met Phe Pro Arg Val Ser Thr Phe Leu Pro Leu Arg Pro Leu Ser Arg 
1               5                   10                  15      


His Pro Leu Ser Ser Gly Ser Pro Glu Thr Ser Ala Ala Ala Ile Met 
            20                  25                  30          


Leu Leu Thr Val Arg His Gly Thr Val Arg Tyr Arg Ser Ser Ala Leu 
        35                  40                  45              


Leu Ala Arg Thr Lys Asn Asn Ile Gln Arg Tyr Phe Gly Thr Asn Ser 
    50                  55                  60                  


Val Ile Cys Ser Lys Lys Asp Lys Gln Ser Val Arg Thr Glu Glu Thr 
65                  70                  75                  80  


Ser Lys Glu Thr Ser Glu Ser Gln Asp Ser Glu Lys Glu Asn Thr Lys 
                85                  90                  95      


Lys Asp Leu Leu Gly Ile Ile Lys Gly Met Lys Val Glu Leu Ser Thr 
            100                 105                 110         


Val Asn Val Arg Thr Thr Lys Pro Pro Lys Arg Arg Pro Leu Lys Ser 
        115                 120                 125             


Leu Glu Ala Thr Leu Gly Arg Leu Arg Arg Ala Thr Glu Tyr Ala Pro 
    130                 135                 140                 


Lys Lys Arg Ile Glu Pro Leu Ser Pro Glu Leu Val Ala Ala Ala Ser 
145                 150                 155                 160 


Ala Val Ala Asp Ser Leu Pro Phe Asp Lys Gln Thr Thr Lys Ser Glu 
                165                 170                 175     


Leu Leu Ser Gln Leu Gln Gln His Glu Glu Glu Ser Arg Ala Gln Arg 
            180                 185                 190         


Asp Ala Lys Arg Pro Lys Ile Ser Phe Ser Asn Ile Ile Ser Asp Met 
        195                 200                 205             


Lys Val Ala Arg Ser Ala Thr Ala Arg Val Arg Ser Arg Pro Glu Leu 
    210                 215                 220                 


Arg Ile Gln Phe Asp Glu Gly Tyr Asp Asn Tyr Pro Gly Gln Glu Lys 
225                 230                 235                 240 


Thr Asp Asp Leu Lys Lys Arg Lys Asn Ile Phe Thr Gly Lys Arg Leu 
                245                 250                 255     


Asn Ile Phe Asp Met Met Ala Val Thr Lys Glu Ala Pro Glu Thr Asp 
            260                 265                 270         


Thr Ser Pro Ser Leu Trp Asp Val Glu Phe Ala Lys Gln Leu Ala Thr 
        275                 280                 285             


Val Asn Glu Gln Pro Leu Gln Asn Gly Phe Glu Glu Leu Ile Gln Trp 
    290                 295                 300                 


Thr Lys Glu Gly Lys Leu Trp Glu Phe Pro Ile Asn Asn Glu Ala Gly 
305                 310                 315                 320 


Phe Asp Asp Asp Gly Ser Glu Phe His Glu His Ile Phe Leu Glu Lys 
                325                 330                 335     


His Leu Glu Ser Phe Pro Lys Gln Gly Pro Ile Arg His Phe Met Glu 
            340                 345                 350         


Leu Val Thr Cys Gly Leu Ser Lys Asn Pro Tyr Leu Ser Val Lys Gln 
        355                 360                 365             


Lys Val Glu His Ile Glu Trp Phe Arg Asn Tyr Phe Asn Glu Lys Lys 
    370                 375                 380                 


Asp Ile Leu Lys Glu Ser Asn Ile Gln Phe Asn 
385                 390                 395 


<210>  1359
<211>  711
<212>  PRT
<213>  Human

<400>  1359

Met Met Ala Asp Ala Lys Tyr Val Leu Cys Arg Trp Glu Lys Arg Leu 
1               5                   10                  15      


Trp Pro Ala Lys Val Leu Ala Arg Thr Ala Thr Ser Thr Lys Asn Lys 
            20                  25                  30          


Arg Arg Lys Glu Tyr Phe Leu Ala Val Gln Ile Leu Ser Leu Glu Glu 
        35                  40                  45              


Lys Ile Lys Val Lys Ser Thr Glu Val Glu Ile Leu Glu Lys Ser Gln 
    50                  55                  60                  


Ile Glu Ala Ile Ala Ser Ser Leu Ala Ser Gln Asn Glu Val Pro Ala 
65                  70                  75                  80  


Ala Pro Leu Glu Glu Leu Ala Tyr Arg Arg Ser Leu Arg Val Ala Leu 
                85                  90                  95      


Asp Val Leu Ser Glu Gly Ser Ile Trp Ser Gln Glu Ser Ser Ala Gly 
            100                 105                 110         


Thr Gly Arg Ala Asp Arg Ser Leu Arg Gly Lys Pro Met Glu His Val 
        115                 120                 125             


Ser Ser Pro Cys Asp Ser Asn Ser Ser Ser Leu Pro Arg Gly Asp Val 
    130                 135                 140                 


Leu Gly Ser Ser Arg Pro His Arg Arg Arg Pro Cys Val Gln Gln Ser 
145                 150                 155                 160 


Leu Ser Ser Ser Phe Thr Cys Glu Lys Asp Pro Glu Cys Lys Val Asp 
                165                 170                 175     


His Lys Lys Gly Leu Arg Lys Ser Glu Asn Pro Arg Gly Pro Leu Val 
            180                 185                 190         


Leu Pro Ala Gly Gly Gly Ala Gln Asp Glu Ser Gly Ser Arg Ile His 
        195                 200                 205             


His Lys Asn Trp Thr Leu Ala Ser Lys Arg Gly Gly Asn Ser Ala Gln 
    210                 215                 220                 


Lys Ala Ser Leu Cys Leu Asn Gly Ser Ser Leu Ser Glu Asp Asp Thr 
225                 230                 235                 240 


Glu Arg Asp Met Gly Ser Lys Gly Gly Ser Trp Ala Ala Pro Ser Leu 
                245                 250                 255     


Pro Ser Gly Val Arg Glu Asp Asp Pro Cys Ala Asn Ala Glu Gly His 
            260                 265                 270         


Asp Pro Gly Leu Pro Leu Gly Ser Leu Thr Ala Pro Pro Ala Pro Glu 
        275                 280                 285             


Pro Ser Ala Cys Ser Glu Pro Gly Glu Cys Pro Ala Lys Lys Arg Pro 
    290                 295                 300                 


Arg Leu Asp Gly Ser Gln Arg Pro Pro Ala Val Gln Leu Glu Pro Met 
305                 310                 315                 320 


Ala Ala Gly Ala Ala Pro Ser Pro Gly Pro Gly Pro Gly Pro Arg Glu 
                325                 330                 335     


Ser Val Thr Pro Arg Ser Thr Ala Arg Leu Gly Pro Pro Pro Ser His 
            340                 345                 350         


Ala Ser Ala Asp Ala Thr Arg Cys Leu Pro Cys Pro Asp Ser Gln Lys 
        355                 360                 365             


Leu Glu Lys Glu Cys Gln Ser Ser Glu Glu Ser Met Gly Ser Asn Ser 
    370                 375                 380                 


Met Arg Ser Ile Leu Glu Glu Asp Glu Glu Asp Glu Glu Pro Pro Arg 
385                 390                 395                 400 


Val Leu Leu Tyr His Glu Pro Arg Ser Phe Glu Val Gly Met Leu Val 
                405                 410                 415     


Trp His Lys His Lys Lys Tyr Pro Phe Trp Pro Ala Val Val Lys Ser 
            420                 425                 430         


Val Arg Gln Arg Asp Lys Lys Ala Ser Val Leu Tyr Ile Glu Gly His 
        435                 440                 445             


Met Asn Pro Lys Met Lys Gly Phe Thr Val Ser Leu Lys Ser Leu Lys 
    450                 455                 460                 


His Phe Asp Cys Lys Glu Lys Gln Thr Leu Leu Asn Gln Ala Arg Glu 
465                 470                 475                 480 


Asp Phe Asn Gln Asp Ile Gly Trp Cys Val Ser Leu Ile Thr Asp Tyr 
                485                 490                 495     


Arg Val Arg Leu Gly Cys Gly Ser Phe Ala Gly Ser Phe Leu Glu Tyr 
            500                 505                 510         


Tyr Ala Ala Asp Ile Ser Tyr Pro Val Arg Lys Ser Ile Gln Gln Asp 
        515                 520                 525             


Val Leu Gly Thr Lys Leu Pro Gln Leu Ser Lys Gly Ser Pro Glu Glu 
    530                 535                 540                 


Pro Val Val Gly Cys Pro Leu Gly Gln Arg Gln Pro Cys Arg Lys Met 
545                 550                 555                 560 


Leu Pro Asp Arg Ser Arg Ala Ala Arg Asp Arg Ala Asn Gln Lys Leu 
                565                 570                 575     


Val Glu Tyr Ile Val Lys Ala Lys Gly Ala Glu Ser His Leu Arg Ala 
            580                 585                 590         


Ile Leu Lys Ser Arg Lys Pro Ser Arg Trp Leu Gln Thr Phe Leu Ser 
        595                 600                 605             


Ser Ser Gln Tyr Val Thr Cys Val Glu Thr Tyr Leu Glu Asp Glu Gly 
    610                 615                 620                 


Gln Leu Asp Leu Val Val Lys Tyr Leu Gln Gly Val Tyr Gln Glu Val 
625                 630                 635                 640 


Gly Ala Lys Val Leu Gln Arg Thr Asn Gly Asp Arg Ile Arg Phe Ile 
                645                 650                 655     


Leu Asp Val Leu Leu Pro Glu Ala Ile Ile Cys Ala Ile Ser Ala Val 
            660                 665                 670         


Asp Glu Val Asp Tyr Lys Thr Ala Glu Glu Lys Tyr Ile Lys Gly Pro 
        675                 680                 685             


Ser Leu Ser Tyr Arg Glu Lys Glu Ile Phe Asp Asn Gln Leu Leu Glu 
    690                 695                 700                 


Glu Arg Asn Arg Arg Arg Arg 
705                 710     


<210>  1360
<211>  578
<212>  PRT
<213>  Human

<400>  1360

Ser Val Leu Glu Ala Leu Ser Gly Val Ala Leu Pro Arg Gly Ser Gly 
1               5                   10                  15      


Ile Val Thr Arg Cys Pro Leu Val Leu Lys Leu Lys Lys Leu Val Asn 
            20                  25                  30          


Glu Asp Lys Trp Arg Gly Lys Val Ser Tyr Gln Asp Tyr Glu Ile Glu 
        35                  40                  45              


Ile Ser Asp Ala Ser Glu Val Glu Lys Glu Ile Asn Lys Ala Gln Asn 
    50                  55                  60                  


Ala Ile Ala Gly Glu Gly Met Gly Ile Ser His Glu Leu Ile Thr Leu 
65                  70                  75                  80  


Glu Ile Ser Ser Arg Asp Val Pro Asp Leu Thr Leu Ile Asp Leu Pro 
                85                  90                  95      


Gly Ile Thr Arg Val Ala Val Gly Asn Gln Pro Ala Asp Ile Gly Tyr 
            100                 105                 110         


Lys Ile Lys Thr Leu Ile Lys Lys Tyr Ile Gln Arg Gln Glu Thr Ile 
        115                 120                 125             


Ser Leu Val Val Val Pro Ser Asn Val Asp Ile Ala Thr Thr Glu Ala 
    130                 135                 140                 


Leu Ser Met Ala Gln Glu Val Asp Pro Glu Gly Asp Arg Thr Ile Gly 
145                 150                 155                 160 


Ile Leu Thr Lys Pro Asp Leu Val Asp Lys Gly Thr Glu Asp Lys Val 
                165                 170                 175     


Val Asp Val Val Arg Asn Leu Val Phe His Leu Lys Lys Gly Tyr Met 
            180                 185                 190         


Ile Val Lys Cys Arg Gly Gln Gln Glu Ile Gln Asp Gln Leu Ser Leu 
        195                 200                 205             


Ser Glu Ala Leu Gln Arg Glu Lys Ile Phe Phe Glu Asn His Pro Tyr 
    210                 215                 220                 


Phe Arg Asp Leu Leu Glu Glu Gly Lys Ala Thr Val Pro Cys Leu Ala 
225                 230                 235                 240 


Glu Lys Leu Thr Ser Glu Leu Ile Thr His Ile Cys Lys Ser Leu Pro 
                245                 250                 255     


Leu Leu Glu Asn Gln Ile Lys Glu Thr His Gln Arg Ile Thr Glu Glu 
            260                 265                 270         


Leu Gln Lys Tyr Gly Val Asp Ile Pro Glu Asp Glu Asn Glu Lys Met 
        275                 280                 285             


Phe Phe Leu Ile Asp Lys Ile Asn Ala Phe Asn Gln Asp Ile Thr Ala 
    290                 295                 300                 


Leu Met Gln Gly Glu Glu Thr Val Gly Glu Glu Asp Ile Arg Leu Phe 
305                 310                 315                 320 


Thr Arg Leu Arg His Glu Phe His Lys Trp Ser Thr Ile Ile Glu Asn 
                325                 330                 335     


Asn Phe Gln Glu Gly His Lys Ile Leu Ser Arg Lys Ile Gln Lys Phe 
            340                 345                 350         


Glu Asn Gln Tyr Arg Gly Arg Glu Leu Pro Gly Phe Val Asn Tyr Arg 
        355                 360                 365             


Thr Phe Glu Thr Ile Val Lys Gln Gln Ile Lys Ala Leu Glu Glu Pro 
    370                 375                 380                 


Ala Val Asp Met Leu His Thr Val Thr Asp Met Val Arg Leu Ala Phe 
385                 390                 395                 400 


Thr Asp Val Ser Ile Lys Asn Phe Glu Glu Phe Phe Asn Leu His Arg 
                405                 410                 415     


Thr Ala Lys Ser Lys Ile Glu Asp Ile Arg Ala Glu Gln Glu Arg Glu 
            420                 425                 430         


Gly Glu Lys Leu Ile Arg Leu His Phe Gln Met Glu Gln Ile Val Tyr 
        435                 440                 445             


Cys Gln Asp Gln Val Tyr Arg Gly Ala Leu Gln Lys Val Arg Glu Lys 
    450                 455                 460                 


Glu Leu Glu Glu Glu Lys Lys Lys Lys Ser Trp Asp Phe Gly Ala Phe 
465                 470                 475                 480 


Gln Ser Ser Ser Ala Thr Asp Ser Ser Met Glu Glu Ile Phe Gln His 
                485                 490                 495     


Leu Met Ala Tyr His Gln Glu Ala Ser Lys Arg Ile Ser Ser His Ile 
            500                 505                 510         


Pro Leu Ile Ile Gln Phe Phe Met Leu Gln Thr Tyr Gly Gln Gln Leu 
        515                 520                 525             


Gln Lys Ala Met Leu Gln Leu Leu Gln Asp Lys Asp Thr Tyr Ser Trp 
    530                 535                 540                 


Leu Leu Lys Glu Arg Ser Asp Thr Ser Asp Lys Arg Lys Phe Leu Lys 
545                 550                 555                 560 


Glu Arg Leu Ala Arg Leu Thr Gln Ala Arg Arg Arg Leu Ala Gln Phe 
                565                 570                 575     


Pro Gly 
        


<210>  1361
<211>  172
<212>  PRT
<213>  Human

<400>  1361

Met Pro Asp Ser Trp Asp Lys Asp Val Tyr Pro Glu Pro Pro Arg Arg 
1               5                   10                  15      


Thr Pro Val Gln Pro Asn Pro Ile Val Tyr Met Met Lys Ala Phe Asp 
            20                  25                  30          


Leu Ile Val Asp Arg Pro Val Thr Leu Val Arg Glu Phe Ile Glu Arg 
        35                  40                  45              


Gln His Ala Lys Asn Arg Tyr Tyr Tyr Tyr His Arg Gln Tyr Arg Arg 
    50                  55                  60                  


Val Pro Asp Ile Thr Glu Cys Lys Glu Glu Asp Ile Met Cys Met Tyr 
65                  70                  75                  80  


Glu Ala Glu Met Gln Trp Lys Arg Asp Tyr Lys Val Asp Gln Glu Ile 
                85                  90                  95      


Ile Asn Ile Met Gln Asp Arg Leu Lys Ala Cys Gln Gln Arg Glu Gly 
            100                 105                 110         


Gln Asn Tyr Gln Gln Asn Cys Ile Lys Glu Val Glu Gln Phe Thr Gln 
        115                 120                 125             


Val Ala Lys Ala Tyr Gln Asp Arg Tyr Gln Asp Leu Gly Ala Tyr Ser 
    130                 135                 140                 


Ser Ala Arg Lys Cys Leu Ala Lys Gln Arg Gln Arg Met Leu Gln Glu 
145                 150                 155                 160 


Arg Lys Ala Ala Lys Glu Ala Ala Ala Ala Thr Ser 
                165                 170         


<210>  1362
<211>  1378
<212>  PRT
<213>  Human

<400>  1362

Met Ser Leu Glu Arg Glu Leu Arg Gln Leu Ser Lys Ala Lys Ala Lys 
1               5                   10                  15      


Ala Gln Arg Ala Gly Gln Arg Arg Glu Glu Ala Ala Leu Cys His Gln 
            20                  25                  30          


Leu Gly Glu Leu Leu Ala Gly His Gly Arg Tyr Ala Glu Ala Leu Glu 
        35                  40                  45              


Gln His Trp Gln Glu Leu Gln Leu Arg Glu Arg Ala Asp Asp Pro Leu 
    50                  55                  60                  


Gly Cys Ala Val Ala His Arg Lys Ile Gly Glu Arg Leu Ala Glu Met 
65                  70                  75                  80  


Glu Asp Tyr Pro Ala Ala Leu Gln His Gln His Gln Tyr Leu Glu Leu 
                85                  90                  95      


Ala His Ser Leu Arg Asn His Thr Glu Leu Gln Arg Ala Trp Ala Thr 
            100                 105                 110         


Ile Gly Arg Thr His Leu Asp Ile Tyr Asp His Cys Gln Ser Arg Asp 
        115                 120                 125             


Ala Leu Leu Gln Ala Gln Ala Ala Phe Glu Lys Ser Leu Ala Ile Val 
    130                 135                 140                 


Asp Glu Glu Leu Glu Gly Thr Leu Ala Gln Gly Glu Leu Asn Glu Met 
145                 150                 155                 160 


Arg Thr Arg Leu Tyr Leu Asn Leu Gly Leu Thr Phe Glu Ser Leu Gln 
                165                 170                 175     


Gln Thr Ala Leu Cys Asn Asp Tyr Phe Arg Lys Ser Ile Phe Leu Ala 
            180                 185                 190         


Glu Gln Asn His Leu Tyr Glu Asp Leu Phe Arg Ala Arg Tyr Asn Leu 
        195                 200                 205             


Gly Thr Ile His Trp Arg Ala Gly Gln His Ser Gln Ala Met Arg Cys 
    210                 215                 220                 


Leu Glu Gly Ala Arg Glu Cys Ala His Thr Met Arg Lys Arg Phe Met 
225                 230                 235                 240 


Glu Ser Glu Cys Cys Val Val Ile Ala Gln Val Leu Gln Asp Leu Gly 
                245                 250                 255     


Asp Phe Leu Ala Ala Lys Arg Ala Leu Lys Lys Ala Tyr Arg Leu Gly 
            260                 265                 270         


Ser Gln Lys Pro Val Gln Arg Ala Ala Ile Cys Gln Asn Leu Gln His 
        275                 280                 285             


Val Leu Ala Val Val Arg Leu Gln Gln Gln Leu Glu Glu Ala Glu Gly 
    290                 295                 300                 


Arg Asp Pro Gln Gly Ala Met Val Ile Cys Glu Gln Leu Gly Asp Leu 
305                 310                 315                 320 


Phe Ser Lys Ala Gly Asp Phe Pro Arg Ala Ala Glu Ala Tyr Gln Lys 
                325                 330                 335     


Gln Leu Arg Phe Ala Glu Leu Leu Asp Arg Pro Gly Ala Glu Arg Ala 
            340                 345                 350         


Ile Ile His Val Ser Leu Ala Thr Thr Leu Gly Asp Met Lys Asp His 
        355                 360                 365             


His Gly Ala Val Arg His Tyr Glu Glu Glu Leu Arg Leu Arg Ser Gly 
    370                 375                 380                 


Asn Val Leu Glu Glu Ala Lys Thr Trp Leu Asn Ile Ala Leu Ser Arg 
385                 390                 395                 400 


Glu Glu Ala Gly Asp Ala Tyr Glu Leu Leu Ala Pro Cys Phe Gln Lys 
                405                 410                 415     


Ala Leu Ser Cys Ala Gln Gln Ala Gln Arg Pro Gln Leu Gln Arg Gln 
            420                 425                 430         


Val Leu Gln His Leu His Thr Val Gln Leu Arg Leu Gln Pro Gln Glu 
        435                 440                 445             


Ala Pro Glu Thr Glu Thr Arg Leu Arg Glu Leu Ser Val Ala Glu Asp 
    450                 455                 460                 


Glu Asp Glu Glu Glu Glu Ala Glu Glu Ala Ala Ala Thr Ala Glu Ser 
465                 470                 475                 480 


Glu Ala Leu Glu Ala Gly Glu Val Glu Leu Ser Glu Gly Glu Asp Asp 
                485                 490                 495     


Thr Asp Gly Leu Thr Pro Gln Leu Glu Glu Asp Glu Glu Leu Gln Gly 
            500                 505                 510         


His Leu Gly Arg Arg Lys Gly Ser Lys Trp Asn Arg Arg Asn Asp Met 
        515                 520                 525             


Gly Glu Thr Leu Leu His Arg Ala Cys Ile Glu Gly Gln Leu Arg Arg 
    530                 535                 540                 


Val Gln Asp Leu Val Arg Gln Gly His Pro Leu Asn Pro Arg Asp Tyr 
545                 550                 555                 560 


Cys Gly Trp Thr Pro Leu His Glu Ala Cys Asn Tyr Gly His Leu Glu 
                565                 570                 575     


Ile Val Arg Phe Leu Leu Asp His Gly Ala Ala Val Asp Asp Pro Gly 
            580                 585                 590         


Gly Gln Gly Cys Glu Gly Ile Thr Pro Leu His Asp Ala Leu Asn Cys 
        595                 600                 605             


Gly His Phe Glu Val Ala Glu Leu Leu Leu Glu Arg Gly Ala Ser Val 
    610                 615                 620                 


Thr Leu Arg Thr Arg Lys Gly Leu Ser Pro Leu Glu Thr Leu Gln Gln 
625                 630                 635                 640 


Trp Val Lys Leu Tyr Arg Arg Asp Leu Asp Leu Glu Thr Arg Gln Lys 
                645                 650                 655     


Ala Arg Ala Met Glu Met Leu Leu Gln Ala Ala Ala Ser Gly Gln Asp 
            660                 665                 670         


Pro His Ser Ser Gln Ala Phe His Thr Pro Ser Ser Leu Leu Phe Asp 
        675                 680                 685             


Pro Glu Thr Ser Pro Pro Leu Ser Pro Cys Pro Glu Pro Pro Ser Asn 
    690                 695                 700                 


Ser Thr Arg Leu Pro Glu Ala Ser Gln Ala His Val Arg Val Ser Pro 
705                 710                 715                 720 


Gly Gln Ala Ala Pro Ala Met Ala Arg Pro Arg Arg Ser Arg His Gly 
                725                 730                 735     


Pro Ala Ser Ser Ser Ser Ser Ser Glu Gly Glu Asp Ser Ala Gly Pro 
            740                 745                 750         


Ala Arg Pro Ser Gln Lys Arg Pro Arg Cys Ser Ala Thr Ala Gln Arg 
        755                 760                 765             


Val Ala Ala Trp Thr Pro Gly Pro Ala Ser Asn Arg Glu Ala Ala Thr 
    770                 775                 780                 


Ala Ser Thr Ser Arg Ala Ala Tyr Gln Ala Ala Ile Arg Gly Val Gly 
785                 790                 795                 800 


Ser Ala Gln Ser Arg Leu Gly Pro Gly Pro Pro Arg Gly His Ser Lys 
                805                 810                 815     


Ala Leu Ala Pro Gln Ala Ala Leu Ile Pro Glu Glu Glu Cys Leu Ala 
            820                 825                 830         


Gly Asp Trp Leu Glu Leu Asp Met Pro Leu Thr Arg Ser Arg Arg Pro 
        835                 840                 845             


Arg Pro Arg Gly Thr Gly Asp Asn Arg Arg Pro Ser Ser Thr Ser Gly 
    850                 855                 860                 


Ser Asp Ser Glu Glu Ser Arg Pro Arg Ala Arg Ala Lys Gln Val Arg 
865                 870                 875                 880 


Leu Thr Cys Met Gln Ser Cys Ser Ala Pro Val Asn Ala Gly Pro Ser 
                885                 890                 895     


Ser Leu Ala Ser Glu Pro Pro Gly Ser Pro Ser Thr Pro Arg Val Ser 
            900                 905                 910         


Glu Pro Ser Gly Asp Ser Ser Ala Ala Gly Gln Pro Leu Gly Pro Ala 
        915                 920                 925             


Pro Pro Pro Pro Ile Arg Val Arg Val Gln Val Gln Asp His Leu Phe 
    930                 935                 940                 


Leu Ile Pro Val Pro His Ser Ser Asp Thr His Ser Val Ala Trp Leu 
945                 950                 955                 960 


Ala Glu Gln Ala Ala Gln Arg Tyr Tyr Gln Thr Cys Gly Leu Leu Pro 
                965                 970                 975     


Arg Leu Thr Leu Arg Lys Glu Gly Ala Leu Leu Ala Pro Gln Asp Leu 
            980                 985                 990         


Ile Pro Asp Val Leu Gln Ser Asn  Asp Glu Val Leu Ala  Glu Val Thr 
        995                 1000                 1005             


Ser Trp  Asp Leu Pro Pro Leu  Thr Asp Arg Tyr Arg  Arg Ala Cys 
    1010                 1015                 1020             


Gln Ser  Leu Gly Gln Gly Glu  His Gln Gln Val Leu  Gln Ala Val 
    1025                 1030                 1035             


Glu Leu  Gln Gly Leu Gly Leu  Ser Phe Ser Ala Cys  Ser Leu Ala 
    1040                 1045                 1050             


Leu Asp  Gln Ala Gln Leu Thr  Pro Leu Leu Arg Ala  Leu Lys Leu 
    1055                 1060                 1065             


His Thr  Ala Leu Arg Glu Leu  Arg Leu Ala Gly Asn  Arg Leu Gly 
    1070                 1075                 1080             


Asp Lys  Cys Val Ala Glu Leu  Val Ala Ala Leu Gly  Thr Met Pro 
    1085                 1090                 1095             


Ser Leu  Ala Leu Leu Asp Leu  Ser Ser Asn His Leu  Gly Pro Glu 
    1100                 1105                 1110             


Gly Leu  Arg Gln Leu Ala Met  Gly Leu Pro Gly Gln  Ala Thr Leu 
    1115                 1120                 1125             


Gln Ser  Leu Glu Glu Leu Asp  Leu Ser Met Asn Pro  Leu Gly Asp 
    1130                 1135                 1140             


Gly Cys  Gly Gln Ser Leu Ala  Ser Leu Leu His Ala  Cys Pro Leu 
    1145                 1150                 1155             


Leu Ser  Thr Leu Arg Leu Gln  Ala Cys Gly Phe Gly  Pro Ser Phe 
    1160                 1165                 1170             


Phe Leu  Ser His Gln Thr Ala  Leu Gly Ser Ala Phe  Gln Asp Ala 
    1175                 1180                 1185             


Glu His  Leu Lys Thr Leu Ser  Leu Ser Tyr Asn Ala  Leu Gly Ala 
    1190                 1195                 1200             


Pro Ala  Leu Ala Arg Thr Leu  Gln Ser Leu Pro Ala  Gly Thr Leu 
    1205                 1210                 1215             


Leu His  Leu Glu Leu Ser Ser  Val Ala Ala Gly Lys  Gly Asp Ser 
    1220                 1225                 1230             


Asp Leu  Met Glu Pro Val Phe  Arg Tyr Leu Ala Lys  Glu Gly Cys 
    1235                 1240                 1245             


Ala Leu  Ala His Leu Thr Leu  Ser Ala Asn His Leu  Gly Asp Lys 
    1250                 1255                 1260             


Ala Val  Arg Asp Leu Cys Arg  Cys Leu Ser Leu Cys  Pro Ser Leu 
    1265                 1270                 1275             


Ile Ser  Leu Asp Leu Ser Ala  Asn Pro Glu Ile Ser  Cys Ala Ser 
    1280                 1285                 1290             


Leu Glu  Glu Leu Leu Ser Thr  Leu Gln Lys Arg Pro  Gln Gly Leu 
    1295                 1300                 1305             


Ser Phe  Leu Gly Leu Ser Gly  Cys Ala Val Gln Gly  Pro Leu Gly 
    1310                 1315                 1320             


Leu Gly  Leu Trp Asp Lys Ile  Ala Ala Gln Leu Arg  Glu Leu Gln 
    1325                 1330                 1335             


Leu Cys  Ser Arg Arg Leu Cys  Ala Glu Asp Arg Asp  Ala Leu Arg 
    1340                 1345                 1350             


Gln Leu  Gln Pro Ser Arg Pro  Gly Pro Gly Glu Cys  Thr Leu Asp 
    1355                 1360                 1365             


His Gly  Ser Lys Leu Phe Phe  Arg Arg Leu 
    1370                 1375             


<210>  1363
<211>  1504
<212>  PRT
<213>  Human

<400>  1363

Met Ala Thr Ala Arg Thr Phe Gly Pro Glu Arg Glu Ala Glu Pro Ala 
1               5                   10                  15      


Lys Glu Ala Arg Val Val Gly Ser Glu Leu Val Asp Thr Tyr Thr Val 
            20                  25                  30          


Tyr Ile Ile Gln Val Thr Asp Gly Ser His Glu Trp Thr Val Lys His 
        35                  40                  45              


Arg Tyr Ser Asp Phe His Asp Leu His Glu Lys Leu Val Ala Glu Arg 
    50                  55                  60                  


Lys Ile Asp Lys Asn Leu Leu Pro Pro Lys Lys Ile Ile Gly Lys Asn 
65                  70                  75                  80  


Ser Arg Ser Leu Val Glu Lys Arg Glu Lys Asp Leu Glu Val Tyr Leu 
                85                  90                  95      


Gln Lys Leu Leu Ala Ala Phe Pro Gly Val Thr Pro Arg Val Leu Ala 
            100                 105                 110         


His Phe Leu His Phe His Phe Tyr Glu Ile Asn Gly Ile Thr Ala Ala 
        115                 120                 125             


Leu Ala Glu Glu Leu Phe Glu Lys Gly Glu Gln Leu Leu Gly Ala Gly 
    130                 135                 140                 


Glu Val Phe Ala Ile Gly Pro Leu Gln Leu Tyr Ala Val Thr Glu Gln 
145                 150                 155                 160 


Leu Gln Gln Gly Lys Pro Thr Cys Ala Ser Gly Asp Ala Lys Thr Asp 
                165                 170                 175     


Leu Gly His Ile Leu Asp Phe Thr Cys Arg Leu Lys Tyr Leu Lys Val 
            180                 185                 190         


Ser Gly Thr Glu Gly Pro Phe Gly Thr Ser Asn Ile Gln Glu Gln Leu 
        195                 200                 205             


Leu Pro Phe Asp Leu Ser Ile Phe Lys Ser Leu His Gln Val Glu Ile 
    210                 215                 220                 


Ser His Cys Asp Ala Lys His Ile Arg Gly Leu Val Ala Ser Lys Pro 
225                 230                 235                 240 


Thr Leu Ala Thr Leu Ser Val Arg Phe Ser Ala Thr Ser Met Lys Glu 
                245                 250                 255     


Val Leu Val Pro Glu Ala Ser Glu Phe Asp Glu Trp Glu Pro Glu Gly 
            260                 265                 270         


Thr Thr Leu Glu Gly Pro Val Thr Ala Val Ile Pro Thr Trp Gln Ala 
        275                 280                 285             


Leu Thr Thr Leu Asp Leu Ser His Asn Ser Ile Ser Glu Ile Asp Glu 
    290                 295                 300                 


Ser Val Lys Leu Ile Pro Lys Ile Glu Phe Leu Asp Leu Ser His Asn 
305                 310                 315                 320 


Gly Leu Leu Val Val Asp Asn Leu Gln His Leu Tyr Asn Leu Val His 
                325                 330                 335     


Leu Asp Leu Ser Tyr Asn Lys Leu Ser Ser Leu Glu Gly Leu His Thr 
            340                 345                 350         


Lys Leu Gly Asn Ile Lys Thr Leu Asn Leu Ala Gly Asn Leu Leu Glu 
        355                 360                 365             


Ser Leu Ser Gly Leu His Lys Leu Tyr Ser Leu Val Asn Leu Asp Leu 
    370                 375                 380                 


Arg Asp Asn Arg Ile Glu Gln Met Glu Glu Val Arg Ser Ile Gly Ser 
385                 390                 395                 400 


Leu Pro Cys Leu Glu His Val Ser Leu Leu Asn Asn Pro Leu Ser Ile 
                405                 410                 415     


Ile Pro Asp Tyr Arg Thr Lys Val Leu Ala Gln Phe Gly Glu Arg Ala 
            420                 425                 430         


Ser Glu Val Cys Leu Asp Asp Thr Val Thr Thr Glu Lys Glu Leu Asp 
        435                 440                 445             


Thr Val Glu Val Leu Lys Ala Ile Gln Lys Ala Lys Glu Val Lys Ser 
    450                 455                 460                 


Lys Leu Ser Asn Pro Glu Lys Lys Gly Gly Glu Asp Ser Arg Leu Ser 
465                 470                 475                 480 


Ala Ala Pro Cys Ile Arg Pro Ser Ser Ser Pro Pro Thr Val Ala Pro 
                485                 490                 495     


Ala Ser Ala Ser Leu Pro Gln Pro Ile Leu Ser Asn Gln Gly Ile Met 
            500                 505                 510         


Phe Val Gln Glu Glu Ala Leu Ala Ser Ser Leu Ser Ser Thr Asp Ser 
        515                 520                 525             


Leu Thr Pro Glu His Gln Pro Ile Ala Gln Gly Cys Ser Asp Ser Leu 
    530                 535                 540                 


Glu Ser Ile Pro Ala Gly Gln Ala Ala Ser Asp Asp Leu Arg Asp Val 
545                 550                 555                 560 


Pro Gly Ala Val Gly Gly Ala Ser Pro Glu His Ala Glu Pro Glu Val 
                565                 570                 575     


Gln Val Val Pro Gly Ser Gly Gln Ile Ile Phe Leu Pro Phe Thr Cys 
            580                 585                 590         


Ile Gly Tyr Thr Ala Thr Asn Gln Asp Phe Ile Gln Arg Leu Ser Thr 
        595                 600                 605             


Leu Ile Arg Gln Ala Ile Glu Arg Gln Leu Pro Ala Trp Ile Glu Ala 
    610                 615                 620                 


Ala Asn Gln Arg Glu Glu Gly Gln Gly Glu Gln Gly Glu Glu Glu Asp 
625                 630                 635                 640 


Glu Glu Glu Glu Glu Glu Glu Asp Val Ala Glu Asn Arg Tyr Phe Glu 
                645                 650                 655     


Met Gly Pro Pro Asp Val Glu Glu Glu Glu Gly Gly Gly Gln Gly Glu 
            660                 665                 670         


Glu Glu Glu Glu Glu Glu Glu Asp Glu Glu Ala Glu Glu Glu Arg Leu 
        675                 680                 685             


Ala Leu Glu Trp Ala Leu Gly Ala Asp Glu Asp Phe Leu Leu Glu His 
    690                 695                 700                 


Ile Arg Ile Leu Lys Val Leu Trp Cys Phe Leu Ile His Val Gln Gly 
705                 710                 715                 720 


Ser Ile Arg Gln Phe Ala Ala Cys Leu Val Leu Thr Asp Phe Gly Ile 
                725                 730                 735     


Ala Val Phe Glu Ile Pro His Gln Glu Ser Arg Gly Ser Ser Gln His 
            740                 745                 750         


Ile Leu Ser Ser Leu Arg Phe Val Phe Cys Phe Pro His Gly Asp Leu 
        755                 760                 765             


Thr Glu Phe Gly Phe Leu Met Pro Glu Leu Cys Leu Val Leu Lys Val 
    770                 775                 780                 


Arg His Ser Glu Asn Thr Leu Phe Ile Ile Ser Asp Ala Ala Asn Leu 
785                 790                 795                 800 


His Glu Phe His Ala Asp Leu Arg Ser Cys Phe Ala Pro Gln His Met 
                805                 810                 815     


Ala Met Leu Cys Ser Pro Ile Leu Tyr Gly Ser His Thr Ser Leu Gln 
            820                 825                 830         


Glu Phe Leu Arg Gln Leu Leu Thr Phe Tyr Lys Val Ala Gly Gly Cys 
        835                 840                 845             


Gln Glu Arg Ser Gln Gly Cys Phe Pro Val Tyr Leu Val Tyr Ser Asp 
    850                 855                 860                 


Lys Arg Met Val Gln Thr Ala Ala Gly Asp Tyr Ser Gly Asn Ile Glu 
865                 870                 875                 880 


Trp Ala Ser Cys Thr Leu Cys Ser Ala Val Arg Arg Ser Cys Cys Ala 
                885                 890                 895     


Pro Ser Glu Ala Val Lys Ser Ala Ala Ile Pro Tyr Trp Leu Leu Leu 
            900                 905                 910         


Thr Pro Gln His Leu Asn Val Ile Lys Ala Asp Phe Asn Pro Met Pro 
        915                 920                 925             


Asn Arg Gly Thr His Asn Cys Arg Asn Arg Asn Ser Phe Lys Leu Ser 
    930                 935                 940                 


Arg Val Pro Leu Ser Thr Val Leu Leu Asp Pro Thr Arg Ser Cys Thr 
945                 950                 955                 960 


Gln Pro Arg Gly Ala Phe Ala Asp Gly His Val Leu Glu Leu Leu Val 
                965                 970                 975     


Gly Tyr Arg Phe Val Thr Ala Ile Phe Val Leu Pro His Glu Lys Phe 
            980                 985                 990         


His Phe Leu Arg Val Tyr Asn Gln  Leu Arg Ala Ser Leu  Gln Asp Leu 
        995                 1000                 1005             


Lys Thr  Val Val Ile Ala Lys  Thr Pro Gly Thr Gly  Gly Ser Pro 
    1010                 1015                 1020             


Gln Gly  Ser Phe Ala Asp Gly  Gln Pro Ala Glu Arg  Arg Ala Ser 
    1025                 1030                 1035             


Asn Asp  Gln Arg Pro Gln Glu  Val Pro Ala Glu Ala  Leu Ala Pro 
    1040                 1045                 1050             


Ala Pro  Ala Glu Val Pro Ala  Pro Ala Pro Ala Ala  Ala Ser Ala 
    1055                 1060                 1065             


Ser Gly  Pro Ala Lys Thr Pro  Ala Pro Ala Glu Ala  Ser Thr Ser 
    1070                 1075                 1080             


Ala Leu  Val Pro Glu Glu Thr  Pro Val Glu Ala Pro  Ala Pro Pro 
    1085                 1090                 1095             


Pro Ala  Glu Ala Pro Ala Gln  Tyr Pro Ser Glu His  Leu Ile Gln 
    1100                 1105                 1110             


Ala Thr  Ser Glu Glu Asn Gln  Ile Pro Ser His Leu  Pro Ala Cys 
    1115                 1120                 1125             


Pro Ser  Leu Arg His Val Ala  Ser Leu Arg Gly Ser  Ala Ile Ile 
    1130                 1135                 1140             


Glu Leu  Phe His Ser Ser Ile  Ala Glu Val Glu Asn  Glu Glu Leu 
    1145                 1150                 1155             


Arg His  Leu Met Trp Ser Ser  Val Val Phe Tyr Gln  Thr Pro Gly 
    1160                 1165                 1170             


Leu Glu  Val Thr Ala Cys Val  Leu Leu Ser Thr Lys  Ala Val Tyr 
    1175                 1180                 1185             


Phe Val  Leu His Asp Gly Leu  Arg Arg Tyr Phe Ser  Glu Pro Leu 
    1190                 1195                 1200             


Gln Asp  Phe Trp His Gln Lys  Asn Thr Asp Tyr Asn  Asn Ser Pro 
    1205                 1210                 1215             


Phe His  Ile Ser Gln Cys Phe  Val Leu Lys Leu Ser  Asp Leu Gln 
    1220                 1225                 1230             


Ser Val  Asn Val Gly Leu Phe  Asp Gln His Phe Arg  Leu Thr Gly 
    1235                 1240                 1245             


Ser Thr  Pro Met Gln Val Val  Thr Cys Leu Thr Arg  Asp Ser Tyr 
    1250                 1255                 1260             


Leu Thr  His Cys Phe Leu Gln  His Leu Met Val Val  Leu Ser Ser 
    1265                 1270                 1275             


Leu Glu  Arg Thr Pro Ser Pro  Glu Pro Val Asp Lys  Asp Phe Tyr 
    1280                 1285                 1290             


Ser Glu  Phe Gly Asn Lys Thr  Thr Gly Lys Met Glu  Asn Tyr Glu 
    1295                 1300                 1305             


Leu Ile  His Ser Ser Arg Val  Lys Phe Thr Tyr Pro  Ser Glu Glu 
    1310                 1315                 1320             


Glu Ile  Gly Asp Leu Thr Phe  Thr Val Ala Gln Lys  Met Ala Glu 
    1325                 1330                 1335             


Pro Glu  Lys Ala Pro Ala Leu  Ser Ile Leu Leu Tyr  Val Gln Ala 
    1340                 1345                 1350             


Phe Gln  Val Gly Met Pro Pro  Pro Gly Cys Cys Arg  Gly Pro Leu 
    1355                 1360                 1365             


Arg Pro  Lys Thr Leu Leu Leu  Thr Ser Ser Glu Ile  Phe Leu Leu 
    1370                 1375                 1380             


Asp Glu  Asp Cys Val His Tyr  Pro Leu Pro Glu Phe  Ala Lys Glu 
    1385                 1390                 1395             


Pro Pro  Gln Arg Asp Arg Tyr  Arg Leu Asp Asp Gly  Arg Arg Val 
    1400                 1405                 1410             


Arg Asp  Leu Asp Arg Val Leu  Met Gly Tyr Gln Thr  Tyr Pro Gln 
    1415                 1420                 1425             


Ala Leu  Thr Leu Val Phe Asp  Asp Val Gln Gly His  Asp Leu Met 
    1430                 1435                 1440             


Gly Ser  Val Thr Leu Asp His  Phe Gly Glu Val Pro  Gly Gly Pro 
    1445                 1450                 1455             


Ala Arg  Ala Ser Gln Gly Arg  Glu Val Gln Trp Gln  Val Phe Val 
    1460                 1465                 1470             


Pro Ser  Ala Glu Ser Arg Glu  Lys Leu Ile Ser Leu  Leu Ala Arg 
    1475                 1480                 1485             


Gln Trp  Glu Ala Leu Cys Gly  Arg Glu Leu Pro Val  Glu Leu Thr 
    1490                 1495                 1500             


Gly 
    


<210>  1364
<211>  663
<212>  PRT
<213>  Human

<400>  1364

Met Ile Glu Lys Met Gln Gly Ser Arg Met Asp Glu Gln Arg Cys Ser 
1               5                   10                  15      


Phe Pro Pro Pro Leu Lys Thr Glu Glu Asp Tyr Ile Pro Tyr Pro Ser 
            20                  25                  30          


Val His Glu Val Leu Gly Arg Glu Gly Pro Phe Pro Leu Ile Leu Leu 
        35                  40                  45              


Pro Gln Phe Gly Gly Tyr Trp Ile Glu Gly Thr Asn His Glu Ile Thr 
    50                  55                  60                  


Ser Ile Pro Glu Thr Glu Pro Leu Gln Ser Pro Thr Thr Lys Val Lys 
65                  70                  75                  80  


Leu Glu Cys Asn Pro Thr Ala Arg Ile Tyr Arg Lys His Phe Leu Gly 
                85                  90                  95      


Lys Glu His Phe Asn Tyr Tyr Ser Leu Asp Thr Ala Leu Gly His Leu 
            100                 105                 110         


Val Phe Ser Leu Lys Tyr Asp Val Ile Gly Asp Gln Glu His Leu Arg 
        115                 120                 125             


Leu Leu Leu Arg Thr Lys Cys Arg Thr Tyr His Asp Val Ile Pro Ile 
    130                 135                 140                 


Ser Cys Leu Thr Glu Phe Pro Asn Val Val Gln Met Ala Lys Leu Val 
145                 150                 155                 160 


Cys Glu Asp Val Asn Val Asp Arg Phe Tyr Pro Val Leu Tyr Pro Lys 
                165                 170                 175     


Ala Ser Arg Leu Ile Val Thr Phe Asp Glu His Val Ile Ser Asn Asn 
            180                 185                 190         


Phe Lys Phe Gly Val Ile Tyr Gln Lys Leu Gly Gln Thr Ser Glu Glu 
        195                 200                 205             


Glu Leu Phe Ser Thr Asn Glu Glu Ser Pro Ala Phe Val Glu Phe Leu 
    210                 215                 220                 


Glu Phe Leu Gly Gln Lys Val Lys Leu Gln Asp Phe Lys Gly Phe Arg 
225                 230                 235                 240 


Gly Gly Leu Asp Val Thr His Gly Gln Thr Gly Thr Glu Ser Val Tyr 
                245                 250                 255     


Cys Asn Phe Arg Asn Lys Glu Ile Met Phe His Val Ser Thr Lys Leu 
            260                 265                 270         


Pro Tyr Thr Glu Gly Asp Ala Gln Gln Leu Gln Arg Lys Arg His Ile 
        275                 280                 285             


Gly Asn Asp Ile Val Ala Val Val Phe Gln Asp Glu Asn Thr Pro Phe 
    290                 295                 300                 


Val Pro Asp Met Ile Ala Ser Asn Phe Leu His Ala Tyr Val Val Val 
305                 310                 315                 320 


Gln Ala Glu Gly Gly Gly Pro Asp Gly Pro Leu Tyr Lys Val Ser Val 
                325                 330                 335     


Thr Ala Arg Asp Asp Val Pro Phe Phe Gly Pro Pro Leu Pro Asp Pro 
            340                 345                 350         


Ala Val Phe Arg Lys Gly Pro Glu Phe Gln Glu Phe Leu Leu Thr Lys 
        355                 360                 365             


Leu Ile Asn Ala Glu Tyr Ala Cys Tyr Lys Ala Glu Lys Phe Ala Lys 
    370                 375                 380                 


Leu Glu Glu Arg Thr Arg Ala Ala Leu Leu Glu Thr Leu Tyr Glu Glu 
385                 390                 395                 400 


Leu His Ile His Ser Gln Ser Met Met Gly Leu Gly Gly Asp Glu Asp 
                405                 410                 415     


Lys Met Glu Asn Gly Ser Gly Gly Gly Gly Phe Phe Glu Ser Phe Lys 
            420                 425                 430         


Arg Val Ile Arg Ser Arg Ser Gln Ser Met Asp Ala Met Gly Leu Ser 
        435                 440                 445             


Asn Lys Lys Pro Asn Thr Val Ser Thr Ser His Ser Gly Ser Phe Ala 
    450                 455                 460                 


Pro Asn Asn Pro Asp Leu Ala Lys Ala Ala Gly Ile Ser Leu Ile Val 
465                 470                 475                 480 


Pro Gly Lys Ser Pro Thr Arg Lys Lys Ser Gly Pro Phe Gly Ser Arg 
                485                 490                 495     


Arg Ser Ser Ala Ile Gly Ile Glu Asn Ile Gln Glu Val Gln Glu Lys 
            500                 505                 510         


Arg Glu Ser Pro Pro Ala Gly Gln Lys Thr Pro Asp Ser Gly His Val 
        515                 520                 525             


Ser Gln Glu Pro Lys Ser Glu Asn Ser Ser Thr Gln Ser Ser Pro Glu 
    530                 535                 540                 


Met Pro Thr Thr Lys Asn Arg Ala Glu Thr Ala Ala Gln Arg Ala Glu 
545                 550                 555                 560 


Ala Leu Lys Asp Phe Ser Arg Ser Ser Ser Ser Ala Ser Ser Phe Ala 
                565                 570                 575     


Ser Val Val Glu Glu Thr Glu Gly Val Asp Gly Glu Asp Thr Gly Leu 
            580                 585                 590         


Glu Ser Val Ser Ser Ser Gly Thr Pro His Lys Arg Asp Ser Phe Ile 
        595                 600                 605             


Tyr Ser Thr Trp Leu Glu Asp Ser Val Ser Thr Thr Ser Gly Gly Ser 
    610                 615                 620                 


Ser Pro Gly Pro Ser Arg Ser Pro His Pro Asp Ala Gly Lys Leu Gly 
625                 630                 635                 640 


Asp Pro Ala Cys Pro Glu Ile Lys Ile Gln Leu Glu Ala Ser Glu Gln 
                645                 650                 655     


His Met Pro Gln Leu Gly Cys 
            660             


<210>  1365
<211>  857
<212>  PRT
<213>  Human

<400>  1365

Met Ala Lys Ala Lys Lys Val Gly Ala Arg Arg Lys Ala Ser Gly Ala 
1               5                   10                  15      


Pro Ala Gly Ala Arg Gly Gly Pro Ala Lys Ala Asn Ser Asn Pro Phe 
            20                  25                  30          


Glu Val Lys Val Asn Arg Gln Lys Phe Gln Ile Leu Gly Arg Lys Thr 
        35                  40                  45              


Arg His Asp Val Gly Leu Pro Gly Val Ser Arg Ala Arg Ala Leu Arg 
    50                  55                  60                  


Lys Arg Thr Gln Thr Leu Leu Lys Glu Tyr Lys Glu Arg Asp Lys Ser 
65                  70                  75                  80  


Asn Val Phe Arg Asp Lys Arg Phe Gly Glu Tyr Asn Ser Asn Met Ser 
                85                  90                  95      


Pro Glu Glu Lys Met Met Lys Arg Phe Ala Leu Glu Gln Gln Arg His 
            100                 105                 110         


His Glu Lys Lys Ser Ile Tyr Asn Leu Asn Glu Asp Glu Glu Leu Thr 
        115                 120                 125             


His Tyr Gly Gln Ser Leu Ala Asp Ile Glu Lys His Asn Asp Ile Val 
    130                 135                 140                 


Asp Ser Asp Ser Asp Ala Glu Asp Arg Gly Thr Leu Ser Ala Glu Leu 
145                 150                 155                 160 


Thr Ala Ala His Phe Gly Gly Gly Gly Gly Leu Leu His Lys Lys Thr 
                165                 170                 175     


Gln Gln Glu Gly Glu Glu Arg Glu Lys Pro Lys Ser Arg Lys Glu Leu 
            180                 185                 190         


Ile Glu Glu Leu Ile Ala Lys Ser Lys Gln Glu Lys Arg Glu Arg Gln 
        195                 200                 205             


Ala Gln Arg Glu Asp Ala Leu Glu Leu Thr Glu Lys Leu Asp Gln Asp 
    210                 215                 220                 


Trp Lys Glu Ile Gln Thr Leu Leu Ser His Lys Thr Pro Lys Ser Glu 
225                 230                 235                 240 


Asn Arg Asp Lys Lys Glu Lys Pro Lys Pro Asp Ala Tyr Asp Met Met 
                245                 250                 255     


Val Arg Glu Leu Gly Phe Glu Met Lys Ala Gln Pro Ser Asn Arg Met 
            260                 265                 270         


Lys Thr Glu Ala Glu Leu Ala Lys Glu Glu Gln Glu His Leu Arg Lys 
        275                 280                 285             


Leu Glu Ala Glu Arg Leu Arg Arg Met Leu Gly Lys Asp Glu Asp Glu 
    290                 295                 300                 


Asn Val Lys Lys Pro Lys His Met Ser Ala Asp Asp Leu Asn Asp Gly 
305                 310                 315                 320 


Phe Val Leu Asp Lys Asp Asp Arg Arg Leu Leu Ser Tyr Lys Asp Gly 
                325                 330                 335     


Lys Met Asn Val Glu Glu Asp Val Gln Glu Glu Gln Ser Lys Glu Ala 
            340                 345                 350         


Ser Asp Pro Glu Ser Asn Glu Glu Glu Gly Asp Ser Ser Gly Gly Glu 
        355                 360                 365             


Asp Thr Glu Glu Ser Asp Ser Pro Asp Ser His Leu Asp Leu Glu Ser 
    370                 375                 380                 


Asn Val Glu Ser Glu Glu Glu Asn Glu Lys Pro Ala Lys Glu Gln Arg 
385                 390                 395                 400 


Gln Thr Pro Gly Lys Gly Leu Ile Ser Gly Lys Glu Arg Ala Gly Lys 
                405                 410                 415     


Ala Thr Arg Asp Glu Leu Pro Tyr Thr Phe Ala Ala Pro Glu Ser Tyr 
            420                 425                 430         


Glu Glu Leu Arg Ser Leu Leu Leu Gly Arg Ser Met Glu Glu Gln Leu 
        435                 440                 445             


Leu Val Val Glu Arg Ile Gln Lys Cys Asn His Pro Ser Leu Ala Glu 
    450                 455                 460                 


Gly Asn Lys Ala Lys Leu Glu Lys Leu Phe Gly Phe Leu Leu Glu Tyr 
465                 470                 475                 480 


Val Gly Asp Leu Ala Thr Asp Asp Pro Pro Asp Leu Thr Val Ile Asp 
                485                 490                 495     


Lys Leu Val Val His Leu Tyr His Leu Cys Gln Met Phe Pro Glu Ser 
            500                 505                 510         


Ala Ser Asp Ala Ile Lys Phe Val Leu Arg Asp Ala Met His Glu Met 
        515                 520                 525             


Glu Glu Met Ile Glu Thr Lys Gly Arg Ala Ala Leu Pro Gly Leu Asp 
    530                 535                 540                 


Val Leu Ile Tyr Leu Lys Ile Thr Gly Leu Leu Phe Pro Thr Ser Asp 
545                 550                 555                 560 


Phe Trp His Pro Val Val Thr Pro Ala Leu Val Cys Leu Ser Gln Leu 
                565                 570                 575     


Leu Thr Lys Cys Pro Ile Leu Ser Leu Gln Asp Val Val Lys Gly Leu 
            580                 585                 590         


Phe Val Cys Cys Leu Phe Leu Glu Tyr Val Ala Leu Ser Gln Arg Phe 
        595                 600                 605             


Ile Pro Glu Leu Ile Asn Phe Leu Leu Gly Ile Leu Tyr Ile Ala Thr 
    610                 615                 620                 


Pro Asn Lys Ala Ser Gln Gly Ser Thr Leu Val His Pro Phe Arg Ala 
625                 630                 635                 640 


Leu Gly Lys Asn Ser Glu Leu Leu Val Val Ser Ala Arg Glu Asp Val 
                645                 650                 655     


Ala Thr Trp Gln Gln Ser Ser Leu Ser Leu Arg Trp Ala Ser Arg Leu 
            660                 665                 670         


Arg Ala Pro Thr Ser Thr Glu Ala Asn His Ile Arg Leu Ser Cys Leu 
        675                 680                 685             


Ala Val Gly Leu Ala Leu Leu Lys Arg Cys Val Leu Met Tyr Gly Ser 
    690                 695                 700                 


Leu Pro Ser Phe His Ala Ile Met Gly Pro Leu Gln Ala Leu Leu Thr 
705                 710                 715                 720 


Asp His Leu Ala Asp Cys Ser His Pro Gln Glu Leu Gln Glu Leu Cys 
                725                 730                 735     


Gln Ser Thr Leu Thr Glu Met Glu Ser Gln Lys Gln Leu Cys Arg Pro 
            740                 745                 750         


Leu Thr Cys Glu Lys Ser Lys Pro Val Pro Leu Lys Leu Phe Thr Pro 
        755                 760                 765             


Arg Leu Val Lys Val Leu Glu Phe Gly Arg Lys Gln Gly Ser Ser Lys 
    770                 775                 780                 


Glu Glu Gln Glu Arg Lys Arg Leu Ile His Lys His Lys Arg Glu Phe 
785                 790                 795                 800 


Lys Gly Ala Val Arg Glu Ile Arg Lys Asp Asn Gln Phe Leu Ala Arg 
                805                 810                 815     


Met Gln Leu Ser Glu Ile Met Glu Arg Asp Ala Glu Arg Lys Arg Lys 
            820                 825                 830         


Val Lys Gln Leu Phe Asn Ser Leu Ala Thr Gln Glu Gly Glu Trp Lys 
        835                 840                 845             


Ala Leu Lys Arg Lys Lys Phe Lys Lys 
    850                 855         


<210>  1366
<211>  211
<212>  PRT
<213>  Human

<400>  1366

Met Ser Leu Ser Ser Leu Cys Pro Val Phe Ser Ala Ala Ala Ser Ser 
1               5                   10                  15      


Leu Gln Val His Leu Leu Lys Asp Gln Leu Ala Ala Glu Ala Ala Ala 
            20                  25                  30          


Arg Leu Glu Ala Gln Ala Arg Val His Gln Leu Leu Leu Gln Asn Lys 
        35                  40                  45              


Asp Met Leu Gln His Ile Ser Leu Leu Val Lys Gln Val Gln Glu Leu 
    50                  55                  60                  


Glu Leu Lys Leu Ser Gly Gln Asn Ala Met Gly Ser Gln Asp Ser Leu 
65                  70                  75                  80  


Leu Glu Ile Thr Phe Arg Ser Gly Ala Leu Pro Val Leu Cys Asp Pro 
                85                  90                  95      


Thr Thr Pro Lys Pro Glu Asp Leu His Ser Pro Pro Leu Gly Ala Gly 
            100                 105                 110         


Leu Ala Asp Phe Ala His Pro Ala Gly Ser Pro Leu Gly Arg Arg Asp 
        115                 120                 125             


Cys Leu Val Lys Leu Glu Cys Phe Arg Phe Leu Pro Pro Glu Asp Thr 
    130                 135                 140                 


Pro Pro Pro Ala Gln Gly Glu Ala Leu Leu Gly Gly Leu Glu Leu Ile 
145                 150                 155                 160 


Lys Phe Arg Glu Ser Gly Ile Ala Ser Glu Tyr Glu Ser Asn Thr Asp 
                165                 170                 175     


Glu Ser Glu Glu Arg Asp Ser Trp Ser Gln Glu Glu Leu Pro Arg Leu 
            180                 185                 190         


Leu Asn Val Leu Gln Arg Gln Glu Leu Gly Asp Gly Leu Asp Asp Glu 
        195                 200                 205             


Ile Ala Val 
    210     


<210>  1367
<211>  535
<212>  PRT
<213>  Human

<400>  1367

Met Ser Glu Gly Glu Ser Gln Thr Val Leu Ser Ser Gly Ser Asp Pro 
1               5                   10                  15      


Lys Val Glu Ser Ser Ser Ser Ala Pro Gly Leu Thr Ser Val Ser Pro 
            20                  25                  30          


Pro Val Thr Ser Thr Thr Ser Ala Ala Ser Pro Glu Glu Glu Glu Glu 
        35                  40                  45              


Ser Glu Asp Glu Ser Glu Ile Leu Glu Glu Ser Pro Cys Gly Arg Trp 
    50                  55                  60                  


Gln Lys Arg Arg Glu Glu Val Asn Gln Arg Asn Val Pro Gly Ile Asp 
65                  70                  75                  80  


Ser Ala Tyr Leu Ala Met Asp Thr Glu Glu Gly Val Glu Val Val Trp 
                85                  90                  95      


Asn Glu Val Gln Phe Ser Glu Arg Lys Asn Tyr Lys Leu Gln Glu Glu 
            100                 105                 110         


Lys Val Arg Ala Val Phe Asp Asn Leu Ile Gln Leu Glu His Leu Asn 
        115                 120                 125             


Ile Val Lys Phe His Lys Tyr Trp Ala Asp Ile Lys Glu Asn Lys Ala 
    130                 135                 140                 


Arg Val Ile Phe Ile Thr Glu Tyr Met Ser Ser Gly Ser Leu Lys Gln 
145                 150                 155                 160 


Phe Leu Lys Lys Thr Lys Lys Asn His Lys Thr Met Asn Glu Lys Ala 
                165                 170                 175     


Trp Lys Arg Trp Cys Thr Gln Ile Leu Ser Ala Leu Ser Tyr Leu His 
            180                 185                 190         


Ser Cys Asp Pro Pro Ile Ile His Gly Asn Leu Thr Cys Asp Thr Ile 
        195                 200                 205             


Phe Ile Gln His Asn Gly Leu Ile Lys Ile Gly Ser Val Ala Pro Asp 
    210                 215                 220                 


Thr Ile Asn Asn His Val Lys Thr Cys Arg Glu Glu Gln Lys Asn Leu 
225                 230                 235                 240 


His Phe Phe Ala Pro Glu Tyr Gly Glu Val Thr Asn Val Thr Thr Ala 
                245                 250                 255     


Val Asp Ile Tyr Ser Phe Gly Met Cys Ala Leu Glu Met Ala Val Leu 
            260                 265                 270         


Glu Ile Gln Gly Asn Gly Glu Ser Ser Tyr Val Pro Gln Glu Ala Ile 
        275                 280                 285             


Ser Ser Ala Ile Gln Leu Leu Glu Asp Pro Leu Gln Arg Glu Phe Ile 
    290                 295                 300                 


Gln Lys Cys Leu Gln Ser Glu Pro Ala Arg Arg Pro Thr Ala Arg Glu 
305                 310                 315                 320 


Leu Leu Phe His Pro Ala Leu Phe Glu Val Pro Ser Leu Lys Leu Leu 
                325                 330                 335     


Ala Ala His Cys Ile Val Gly His Gln His Met Ile Pro Glu Asn Ala 
            340                 345                 350         


Leu Glu Glu Ile Thr Lys Asn Met Asp Thr Ser Ala Val Leu Ala Glu 
        355                 360                 365             


Ile Pro Ala Gly Pro Gly Arg Glu Pro Val Gln Thr Leu Tyr Ser Gln 
    370                 375                 380                 


Ser Pro Ala Leu Glu Leu Asp Lys Phe Leu Glu Asp Val Arg Asn Gly 
385                 390                 395                 400 


Ile Tyr Pro Leu Thr Ala Phe Gly Leu Pro Arg Pro Gln Gln Pro Gln 
                405                 410                 415     


Gln Glu Glu Val Thr Ser Pro Val Val Pro Pro Ser Val Lys Thr Pro 
            420                 425                 430         


Thr Pro Glu Pro Ala Glu Val Glu Thr Arg Lys Val Val Leu Met Gln 
        435                 440                 445             


Cys Asn Ile Glu Ser Val Glu Glu Gly Val Lys His His Leu Thr Leu 
    450                 455                 460                 


Leu Leu Lys Leu Glu Asp Lys Leu Asn Arg His Leu Ser Cys Asp Leu 
465                 470                 475                 480 


Met Pro Asn Glu Asn Ile Pro Glu Leu Ala Ala Glu Leu Val Gln Leu 
                485                 490                 495     


Gly Phe Ile Ser Glu Ala Asp Gln Ser Arg Leu Thr Ser Leu Leu Glu 
            500                 505                 510         


Glu Thr Leu Asn Lys Phe Asn Phe Ala Arg Asn Ser Thr Leu Asn Ser 
        515                 520                 525             


Ala Ala Val Thr Val Ser Ser 
    530                 535 


<210>  1368
<211>  1014
<212>  PRT
<213>  Human

<400>  1368

Met Ala Glu Ser Ser Asp Lys Leu Tyr Arg Val Glu Tyr Ala Lys Ser 
1               5                   10                  15      


Gly Arg Ala Ser Cys Lys Lys Cys Ser Glu Ser Ile Pro Lys Asp Ser 
            20                  25                  30          


Leu Arg Met Ala Ile Met Val Gln Ser Pro Met Phe Asp Gly Lys Val 
        35                  40                  45              


Pro His Trp Tyr His Phe Ser Cys Phe Trp Lys Val Gly His Ser Ile 
    50                  55                  60                  


Arg His Pro Asp Val Glu Val Asp Gly Phe Ser Glu Leu Arg Trp Asp 
65                  70                  75                  80  


Asp Gln Gln Lys Val Lys Lys Thr Ala Glu Ala Gly Gly Val Thr Gly 
                85                  90                  95      


Lys Gly Gln Asp Gly Ile Gly Ser Lys Ala Glu Lys Thr Leu Gly Asp 
            100                 105                 110         


Phe Ala Ala Glu Tyr Ala Lys Ser Asn Arg Ser Thr Cys Lys Gly Cys 
        115                 120                 125             


Met Glu Lys Ile Glu Lys Gly Gln Val Arg Leu Ser Lys Lys Met Val 
    130                 135                 140                 


Asp Pro Glu Lys Pro Gln Leu Gly Met Ile Asp Arg Trp Tyr His Pro 
145                 150                 155                 160 


Gly Cys Phe Val Lys Asn Arg Glu Glu Leu Gly Phe Arg Pro Glu Tyr 
                165                 170                 175     


Ser Ala Ser Gln Leu Lys Gly Phe Ser Leu Leu Ala Thr Glu Asp Lys 
            180                 185                 190         


Glu Ala Leu Lys Lys Gln Leu Pro Gly Val Lys Ser Glu Gly Lys Arg 
        195                 200                 205             


Lys Gly Asp Glu Val Asp Gly Val Asp Glu Val Ala Lys Lys Lys Ser 
    210                 215                 220                 


Lys Lys Glu Lys Asp Lys Asp Ser Lys Leu Glu Lys Ala Leu Lys Ala 
225                 230                 235                 240 


Gln Asn Asp Leu Ile Trp Asn Ile Lys Asp Glu Leu Lys Lys Val Cys 
                245                 250                 255     


Ser Thr Asn Asp Leu Lys Glu Leu Leu Ile Phe Asn Lys Gln Gln Val 
            260                 265                 270         


Pro Ser Gly Glu Ser Ala Ile Leu Asp Arg Val Ala Asp Gly Met Val 
        275                 280                 285             


Phe Gly Ala Leu Leu Pro Cys Glu Glu Cys Ser Gly Gln Leu Val Phe 
    290                 295                 300                 


Lys Ser Asp Ala Tyr Tyr Cys Thr Gly Asp Val Thr Ala Trp Thr Lys 
305                 310                 315                 320 


Cys Met Val Lys Thr Gln Thr Pro Asn Arg Lys Glu Trp Val Thr Pro 
                325                 330                 335     


Lys Glu Phe Arg Glu Ile Ser Tyr Leu Lys Lys Leu Lys Val Lys Lys 
            340                 345                 350         


Gln Asp Arg Ile Phe Pro Pro Glu Thr Ser Ala Ser Val Ala Ala Thr 
        355                 360                 365             


Pro Pro Pro Ser Thr Ala Ser Ala Pro Ala Ala Val Asn Ser Ser Ala 
    370                 375                 380                 


Ser Ala Asp Lys Pro Leu Ser Asn Met Lys Ile Leu Thr Leu Gly Lys 
385                 390                 395                 400 


Leu Ser Arg Asn Lys Asp Glu Val Lys Ala Met Ile Glu Lys Leu Gly 
                405                 410                 415     


Gly Lys Leu Thr Gly Thr Ala Asn Lys Ala Ser Leu Cys Ile Ser Thr 
            420                 425                 430         


Lys Lys Glu Val Glu Lys Met Asn Lys Lys Met Glu Glu Val Lys Glu 
        435                 440                 445             


Ala Asn Ile Arg Val Val Ser Glu Asp Phe Leu Gln Asp Val Ser Ala 
    450                 455                 460                 


Ser Thr Lys Ser Leu Gln Glu Leu Phe Leu Ala His Ile Leu Ser Pro 
465                 470                 475                 480 


Trp Gly Ala Glu Val Lys Ala Glu Pro Val Glu Val Val Ala Pro Arg 
                485                 490                 495     


Gly Lys Ser Gly Ala Ala Leu Ser Lys Lys Ser Lys Gly Gln Val Lys 
            500                 505                 510         


Glu Glu Gly Ile Asn Lys Ser Glu Lys Arg Met Lys Leu Thr Leu Lys 
        515                 520                 525             


Gly Gly Ala Ala Val Asp Pro Asp Ser Gly Leu Glu His Ser Ala His 
    530                 535                 540                 


Val Leu Glu Lys Gly Gly Lys Val Phe Ser Ala Thr Leu Gly Leu Val 
545                 550                 555                 560 


Asp Ile Val Lys Gly Thr Asn Ser Tyr Tyr Lys Leu Gln Leu Leu Glu 
                565                 570                 575     


Asp Asp Lys Glu Asn Arg Tyr Trp Ile Phe Arg Ser Trp Gly Arg Val 
            580                 585                 590         


Gly Thr Val Ile Gly Ser Asn Lys Leu Glu Gln Met Pro Ser Lys Glu 
        595                 600                 605             


Asp Ala Ile Glu His Phe Met Lys Leu Tyr Glu Glu Lys Thr Gly Asn 
    610                 615                 620                 


Ala Trp His Ser Lys Asn Phe Thr Lys Tyr Pro Lys Lys Phe Tyr Pro 
625                 630                 635                 640 


Leu Glu Ile Asp Tyr Gly Gln Asp Glu Glu Ala Val Lys Lys Leu Thr 
                645                 650                 655     


Val Asn Pro Gly Thr Lys Ser Lys Leu Pro Lys Pro Val Gln Asp Leu 
            660                 665                 670         


Ile Lys Met Ile Phe Asp Val Glu Ser Met Lys Lys Ala Met Val Glu 
        675                 680                 685             


Tyr Glu Ile Asp Leu Gln Lys Met Pro Leu Gly Lys Leu Ser Lys Arg 
    690                 695                 700                 


Gln Ile Gln Ala Ala Tyr Ser Ile Leu Ser Glu Val Gln Gln Ala Val 
705                 710                 715                 720 


Ser Gln Gly Ser Ser Asp Ser Gln Ile Leu Asp Leu Ser Asn Arg Phe 
                725                 730                 735     


Tyr Thr Leu Ile Pro His Asp Phe Gly Met Lys Lys Pro Pro Leu Leu 
            740                 745                 750         


Asn Asn Ala Asp Ser Val Gln Ala Lys Val Glu Met Leu Asp Asn Leu 
        755                 760                 765             


Leu Asp Ile Glu Val Ala Tyr Ser Leu Leu Arg Gly Gly Ser Asp Asp 
    770                 775                 780                 


Ser Ser Lys Asp Pro Ile Asp Val Asn Tyr Glu Lys Leu Lys Thr Asp 
785                 790                 795                 800 


Ile Lys Val Val Asp Arg Asp Ser Glu Glu Ala Glu Ile Ile Arg Lys 
                805                 810                 815     


Tyr Val Lys Asn Thr His Ala Thr Thr His Asn Ala Tyr Asp Leu Glu 
            820                 825                 830         


Val Ile Asp Ile Phe Lys Ile Glu Arg Glu Gly Glu Cys Gln Arg Tyr 
        835                 840                 845             


Lys Pro Phe Lys Gln Leu His Asn Arg Arg Leu Leu Trp His Gly Ser 
    850                 855                 860                 


Arg Thr Thr Asn Phe Ala Gly Ile Leu Ser Gln Gly Leu Arg Ile Ala 
865                 870                 875                 880 


Pro Pro Glu Ala Pro Val Thr Gly Tyr Met Phe Gly Lys Gly Ile Tyr 
                885                 890                 895     


Phe Ala Asp Met Val Ser Lys Ser Ala Asn Tyr Cys His Thr Ser Gln 
            900                 905                 910         


Gly Asp Pro Ile Gly Leu Ile Leu Leu Gly Glu Val Ala Leu Gly Asn 
        915                 920                 925             


Met Tyr Glu Leu Lys His Ala Ser His Ile Ser Lys Leu Pro Lys Gly 
    930                 935                 940                 


Lys His Ser Val Lys Gly Leu Gly Lys Thr Thr Pro Asp Pro Ser Ala 
945                 950                 955                 960 


Asn Ile Ser Leu Asp Gly Val Asp Val Pro Leu Gly Thr Gly Ile Ser 
                965                 970                 975     


Ser Gly Val Asn Asp Thr Ser Leu Leu Tyr Asn Glu Tyr Ile Val Tyr 
            980                 985                 990         


Asp Ile Ala Gln Val Asn Leu Lys  Tyr Leu Leu Lys Leu  Lys Phe Asn 
        995                 1000                 1005             


Phe Lys  Thr Ser Leu Trp 
    1010                 


<210>  1369
<211>  1178
<212>  PRT
<213>  Human

<400>  1369

Met Leu Lys Phe Arg Thr Val His Gly Gly Leu Arg Leu Leu Gly Ile 
1               5                   10                  15      


Arg Arg Thr Ser Thr Ala Pro Ala Ala Ser Pro Asn Val Arg Arg Leu 
            20                  25                  30          


Glu Tyr Lys Pro Ile Lys Lys Val Met Val Ala Asn Arg Gly Glu Ile 
        35                  40                  45              


Ala Ile Arg Val Phe Arg Ala Cys Thr Glu Leu Gly Ile Arg Thr Val 
    50                  55                  60                  


Ala Ile Tyr Ser Glu Gln Asp Thr Gly Gln Met His Arg Gln Lys Ala 
65                  70                  75                  80  


Asp Glu Ala Tyr Leu Ile Gly Arg Gly Leu Ala Pro Val Gln Ala Tyr 
                85                  90                  95      


Leu His Ile Pro Asp Ile Ile Lys Val Ala Lys Glu Asn Asn Val Asp 
            100                 105                 110         


Ala Val His Pro Gly Tyr Gly Phe Leu Ser Glu Arg Ala Asp Phe Ala 
        115                 120                 125             


Gln Ala Cys Gln Asp Ala Gly Val Arg Phe Ile Gly Pro Ser Pro Glu 
    130                 135                 140                 


Val Val Arg Lys Met Gly Asp Lys Val Glu Ala Arg Ala Ile Ala Ile 
145                 150                 155                 160 


Ala Ala Gly Val Pro Val Val Pro Gly Thr Asp Ala Pro Ile Thr Ser 
                165                 170                 175     


Leu His Glu Ala His Glu Phe Ser Asn Thr Tyr Gly Phe Pro Ile Ile 
            180                 185                 190         


Phe Lys Ala Ala Tyr Gly Gly Gly Gly Arg Gly Met Arg Val Val His 
        195                 200                 205             


Ser Tyr Glu Glu Leu Glu Glu Asn Tyr Thr Arg Ala Tyr Ser Glu Ala 
    210                 215                 220                 


Leu Ala Ala Phe Gly Asn Gly Ala Leu Phe Val Glu Lys Phe Ile Glu 
225                 230                 235                 240 


Lys Pro Arg His Ile Glu Val Gln Ile Leu Gly Asp Gln Tyr Gly Asn 
                245                 250                 255     


Ile Leu His Leu Tyr Glu Arg Asp Cys Ser Ile Gln Arg Arg His Gln 
            260                 265                 270         


Lys Val Val Glu Ile Ala Pro Ala Ala His Leu Asp Pro Gln Leu Arg 
        275                 280                 285             


Thr Arg Leu Thr Ser Asp Ser Val Lys Leu Ala Lys Gln Val Gly Tyr 
    290                 295                 300                 


Glu Asn Ala Gly Thr Val Glu Phe Leu Val Asp Arg His Gly Lys His 
305                 310                 315                 320 


Tyr Phe Ile Glu Val Asn Ser Arg Leu Gln Val Glu His Thr Val Thr 
                325                 330                 335     


Glu Glu Ile Thr Asp Val Asp Leu Val His Ala Gln Ile His Val Ala 
            340                 345                 350         


Glu Gly Arg Ser Leu Pro Asp Leu Gly Leu Arg Gln Glu Asn Ile Arg 
        355                 360                 365             


Ile Asn Gly Cys Ala Ile Gln Cys Arg Val Thr Thr Glu Asp Pro Ala 
    370                 375                 380                 


Arg Ser Phe Gln Pro Asp Thr Gly Arg Ile Glu Val Phe Arg Ser Gly 
385                 390                 395                 400 


Glu Gly Met Gly Ile Arg Leu Asp Asn Ala Ser Ala Phe Gln Gly Ala 
                405                 410                 415     


Val Ile Ser Pro His Tyr Asp Ser Leu Leu Val Lys Val Ile Ala His 
            420                 425                 430         


Gly Lys Asp His Pro Thr Ala Ala Thr Lys Met Ser Arg Ala Leu Ala 
        435                 440                 445             


Glu Phe Arg Val Arg Gly Val Lys Thr Asn Ile Ala Phe Leu Gln Asn 
    450                 455                 460                 


Val Leu Asn Asn Gln Gln Phe Leu Ala Gly Thr Val Asp Thr Gln Phe 
465                 470                 475                 480 


Ile Asp Glu Asn Pro Glu Leu Phe Gln Leu Arg Pro Ala Gln Asn Arg 
                485                 490                 495     


Ala Gln Lys Leu Leu His Tyr Leu Gly His Val Met Val Asn Gly Pro 
            500                 505                 510         


Thr Thr Pro Ile Pro Val Lys Ala Ser Pro Ser Pro Thr Asp Pro Val 
        515                 520                 525             


Val Pro Ala Val Pro Ile Gly Pro Pro Pro Ala Gly Phe Arg Asp Ile 
    530                 535                 540                 


Leu Leu Arg Glu Gly Pro Glu Gly Phe Ala Arg Ala Val Arg Asn His 
545                 550                 555                 560 


Pro Gly Leu Leu Leu Met Asp Thr Thr Phe Arg Asp Ala His Gln Ser 
                565                 570                 575     


Leu Leu Ala Thr Arg Val Arg Thr His Asp Leu Lys Lys Ile Ala Pro 
            580                 585                 590         


Tyr Val Ala His Asn Phe Ser Lys Leu Phe Ser Met Glu Asn Trp Gly 
        595                 600                 605             


Gly Ala Thr Phe Asp Val Ala Met Arg Phe Leu Tyr Glu Cys Pro Trp 
    610                 615                 620                 


Arg Arg Leu Gln Glu Leu Arg Glu Leu Ile Pro Asn Ile Pro Phe Gln 
625                 630                 635                 640 


Met Leu Leu Arg Gly Ala Asn Ala Val Gly Tyr Thr Asn Tyr Pro Asp 
                645                 650                 655     


Asn Val Val Phe Lys Phe Cys Glu Val Ala Lys Glu Asn Gly Met Asp 
            660                 665                 670         


Val Phe Arg Val Phe Asp Ser Leu Asn Tyr Leu Pro Asn Met Leu Leu 
        675                 680                 685             


Gly Met Glu Ala Ala Gly Ser Ala Gly Gly Val Val Glu Ala Ala Ile 
    690                 695                 700                 


Ser Tyr Thr Gly Asp Val Ala Asp Pro Ser Arg Thr Lys Tyr Ser Leu 
705                 710                 715                 720 


Gln Tyr Tyr Met Gly Leu Ala Glu Glu Leu Val Arg Ala Gly Thr His 
                725                 730                 735     


Ile Leu Cys Ile Lys Asp Met Ala Gly Leu Leu Lys Pro Thr Ala Cys 
            740                 745                 750         


Thr Met Leu Val Ser Ser Leu Arg Asp Arg Phe Pro Asp Leu Pro Leu 
        755                 760                 765             


His Ile His Thr His Asp Thr Ser Gly Ala Gly Val Ala Ala Met Leu 
    770                 775                 780                 


Ala Cys Ala Gln Ala Gly Ala Asp Val Val Asp Val Ala Ala Asp Ser 
785                 790                 795                 800 


Met Ser Gly Met Thr Ser Gln Pro Ser Met Gly Ala Leu Val Ala Cys 
                805                 810                 815     


Thr Arg Gly Thr Pro Leu Asp Thr Glu Val Pro Met Glu Arg Val Phe 
            820                 825                 830         


Asp Tyr Ser Glu Tyr Trp Glu Gly Ala Arg Gly Leu Tyr Ala Ala Phe 
        835                 840                 845             


Asp Cys Thr Ala Thr Met Lys Ser Gly Asn Ser Asp Val Tyr Glu Asn 
    850                 855                 860                 


Glu Ile Pro Gly Gly Gln Tyr Thr Asn Leu His Phe Gln Ala His Ser 
865                 870                 875                 880 


Met Gly Leu Gly Ser Lys Phe Lys Glu Val Lys Lys Ala Tyr Val Glu 
                885                 890                 895     


Ala Asn Gln Met Leu Gly Asp Leu Ile Lys Val Thr Pro Ser Ser Lys 
            900                 905                 910         


Ile Val Gly Asp Leu Ala Gln Phe Met Val Gln Asn Gly Leu Ser Arg 
        915                 920                 925             


Ala Glu Ala Glu Ala Gln Ala Glu Glu Leu Ser Phe Pro Arg Ser Val 
    930                 935                 940                 


Val Glu Phe Leu Gln Gly Tyr Ile Gly Val Pro His Gly Gly Phe Pro 
945                 950                 955                 960 


Glu Pro Phe Arg Ser Lys Val Leu Lys Asp Leu Pro Arg Val Glu Gly 
                965                 970                 975     


Arg Pro Gly Ala Ser Leu Pro Pro Leu Asp Leu Gln Ala Leu Glu Lys 
            980                 985                 990         


Glu Leu Val Asp Arg His Gly Glu  Glu Val Thr Pro Glu  Asp Val Leu 
        995                 1000                 1005             


Ser Ala  Ala Met Tyr Pro Asp  Val Phe Ala His Phe  Lys Asp Phe 
    1010                 1015                 1020             


Thr Ala  Thr Phe Gly Pro Leu  Asp Ser Leu Asn Thr  Arg Leu Phe 
    1025                 1030                 1035             


Leu Gln  Gly Pro Lys Ile Ala  Glu Glu Phe Glu Val  Glu Leu Glu 
    1040                 1045                 1050             


Arg Gly  Lys Thr Leu His Ile  Lys Ala Leu Ala Val  Ser Asp Leu 
    1055                 1060                 1065             


Asn Arg  Ala Gly Gln Arg Gln  Val Phe Phe Glu Leu  Asn Gly Gln 
    1070                 1075                 1080             


Leu Arg  Ser Ile Leu Val Lys  Asp Thr Gln Ala Met  Lys Glu Met 
    1085                 1090                 1095             


His Phe  His Pro Lys Ala Leu  Lys Asp Val Lys Gly  Gln Ile Gly 
    1100                 1105                 1110             


Ala Pro  Met Pro Gly Lys Val  Ile Asp Ile Lys Val  Val Ala Gly 
    1115                 1120                 1125             


Ala Lys  Val Ala Lys Gly Gln  Pro Leu Cys Val Leu  Ser Ala Met 
    1130                 1135                 1140             


Lys Met  Glu Thr Val Val Thr  Ser Pro Met Glu Gly  Thr Val Arg 
    1145                 1150                 1155             


Lys Val  His Val Thr Lys Asp  Met Thr Leu Glu Gly  Asp Asp Leu 
    1160                 1165                 1170             


Ile Leu  Glu Ile Glu 
    1175             


<210>  1370
<211>  1066
<212>  PRT
<213>  Human

<400>  1370

Met Gly Phe Glu Leu Asp Arg Phe Asp Gly Asp Val Asp Pro Asp Leu 
1               5                   10                  15      


Lys Cys Ala Leu Cys His Lys Val Leu Glu Asp Pro Leu Thr Thr Pro 
            20                  25                  30          


Cys Gly His Val Phe Cys Ala Gly Cys Val Leu Pro Trp Val Val Gln 
        35                  40                  45              


Glu Gly Ser Cys Pro Ala Arg Cys Arg Gly Arg Leu Ser Ala Lys Glu 
    50                  55                  60                  


Leu Asn His Val Leu Pro Leu Lys Arg Leu Ile Leu Lys Leu Asp Ile 
65                  70                  75                  80  


Lys Cys Ala Tyr Ala Thr Arg Gly Cys Gly Arg Val Val Lys Leu Gln 
                85                  90                  95      


Gln Leu Pro Glu His Leu Glu Arg Cys Asp Phe Ala Pro Ala Arg Cys 
            100                 105                 110         


Arg His Ala Gly Cys Gly Gln Val Leu Leu Arg Arg Asp Val Glu Ala 
        115                 120                 125             


His Met Arg Asp Ala Cys Asp Ala Arg Pro Val Gly Arg Cys Gln Glu 
    130                 135                 140                 


Gly Cys Gly Leu Pro Leu Thr His Gly Glu Gln Arg Ala Gly Gly His 
145                 150                 155                 160 


Cys Cys Ala Arg Ala Leu Arg Ala His Asn Gly Ala Leu Gln Ala Arg 
                165                 170                 175     


Leu Gly Ala Leu His Lys Ala Leu Lys Lys Glu Ala Leu Arg Ala Gly 
            180                 185                 190         


Lys Arg Glu Lys Ser Leu Val Ala Gln Leu Ala Ala Ala Gln Leu Glu 
        195                 200                 205             


Leu Gln Met Thr Ala Leu Arg Tyr Gln Lys Lys Phe Thr Glu Tyr Ser 
    210                 215                 220                 


Ala Arg Leu Asp Ser Leu Ser Arg Cys Val Ala Ala Pro Pro Gly Gly 
225                 230                 235                 240 


Lys Gly Glu Glu Thr Lys Ser Leu Thr Leu Val Leu His Arg Asp Ser 
                245                 250                 255     


Gly Ser Leu Gly Phe Asn Ile Ile Gly Gly Arg Pro Ser Val Asp Asn 
            260                 265                 270         


His Asp Gly Ser Ser Ser Glu Gly Ile Phe Val Ser Lys Ile Val Asp 
        275                 280                 285             


Ser Gly Pro Ala Ala Lys Glu Gly Gly Leu Gln Ile His Asp Arg Ile 
    290                 295                 300                 


Ile Glu Val Asn Gly Arg Asp Leu Ser Arg Ala Thr His Asp Gln Ala 
305                 310                 315                 320 


Val Glu Ala Phe Lys Thr Ala Lys Glu Pro Ile Val Val Gln Val Leu 
                325                 330                 335     


Arg Arg Thr Pro Arg Thr Lys Met Phe Thr Pro Pro Ser Glu Ser Gln 
            340                 345                 350         


Leu Val Asp Thr Gly Thr Gln Thr Asp Ile Thr Phe Glu His Ile Met 
        355                 360                 365             


Ala Leu Thr Lys Met Ser Ser Pro Ser Pro Pro Val Leu Asp Pro Tyr 
    370                 375                 380                 


Leu Leu Pro Glu Glu His Pro Ser Ala His Glu Tyr Tyr Asp Pro Asn 
385                 390                 395                 400 


Asp Tyr Ile Gly Asp Ile His Gln Glu Met Asp Arg Glu Glu Leu Glu 
                405                 410                 415     


Leu Glu Glu Val Asp Leu Tyr Arg Met Asn Ser Gln Asp Lys Leu Gly 
            420                 425                 430         


Leu Thr Val Cys Tyr Arg Thr Asp Asp Glu Asp Asp Ile Gly Ile Tyr 
        435                 440                 445             


Ile Ser Glu Ile Asp Pro Asn Ser Ile Ala Ala Lys Asp Gly Arg Ile 
    450                 455                 460                 


Arg Glu Gly Asp Arg Ile Ile Gln Ile Asn Gly Ile Glu Val Gln Asn 
465                 470                 475                 480 


Arg Glu Glu Ala Val Ala Leu Leu Thr Ser Glu Glu Asn Lys Asn Phe 
                485                 490                 495     


Ser Leu Leu Ile Ala Arg Pro Glu Leu Gln Leu Asp Glu Gly Trp Met 
            500                 505                 510         


Asp Asp Asp Arg Asn Asp Phe Leu Asp Asp Leu His Met Asp Met Leu 
        515                 520                 525             


Glu Glu Gln His His Gln Ala Met Gln Phe Thr Ala Ser Val Leu Gln 
    530                 535                 540                 


Gln Lys Lys His Asp Glu Asp Gly Gly Thr Thr Asp Thr Ala Thr Ile 
545                 550                 555                 560 


Leu Ser Asn Gln His Glu Lys Asp Ser Gly Val Gly Arg Thr Asp Glu 
                565                 570                 575     


Ser Thr Arg Asn Asp Glu Ser Ser Glu Gln Glu Asn Asn Gly Asp Asp 
            580                 585                 590         


Ala Thr Ala Ser Ser Asn Pro Leu Ala Gly Gln Arg Lys Leu Thr Cys 
        595                 600                 605             


Ser Gln Asp Thr Leu Gly Ser Gly Asp Leu Pro Phe Ser Asn Glu Ser 
    610                 615                 620                 


Phe Ile Ser Ala Asp Cys Thr Asp Ala Asp Tyr Leu Gly Ile Pro Val 
625                 630                 635                 640 


Asp Glu Cys Glu Arg Phe Arg Glu Leu Leu Glu Leu Lys Cys Gln Val 
                645                 650                 655     


Lys Ser Ala Thr Pro Tyr Gly Leu Tyr Tyr Pro Ser Gly Pro Leu Asp 
            660                 665                 670         


Ala Gly Lys Ser Asp Pro Glu Ser Val Asp Lys Glu Leu Glu Leu Leu 
        675                 680                 685             


Asn Glu Glu Leu Arg Ser Ile Glu Leu Glu Cys Leu Ser Ile Val Arg 
    690                 695                 700                 


Ala His Lys Met Gln Gln Leu Lys Glu Gln Tyr Arg Glu Ser Trp Met 
705                 710                 715                 720 


Leu His Asn Ser Gly Phe Arg Asn Tyr Asn Thr Ser Ile Asp Val Arg 
                725                 730                 735     


Arg His Glu Leu Ser Asp Ile Thr Glu Leu Pro Glu Lys Ser Asp Lys 
            740                 745                 750         


Asp Ser Ser Ser Ala Tyr Asn Thr Gly Glu Ser Cys Arg Ser Thr Pro 
        755                 760                 765             


Leu Thr Leu Glu Ile Ser Pro Asp Asn Ser Leu Arg Arg Ala Ala Glu 
    770                 775                 780                 


Gly Ile Ser Cys Pro Ser Ser Glu Gly Ala Val Gly Thr Thr Glu Ala 
785                 790                 795                 800 


Tyr Gly Pro Ala Ser Lys Asn Leu Leu Ser Ile Thr Glu Asp Pro Glu 
                805                 810                 815     


Val Gly Thr Pro Thr Tyr Ser Pro Ser Leu Lys Glu Leu Asp Pro Asn 
            820                 825                 830         


Gln Pro Leu Glu Ser Lys Glu Arg Arg Ala Ser Asp Gly Ser Arg Ser 
        835                 840                 845             


Pro Thr Pro Ser Gln Lys Leu Gly Ser Ala Tyr Leu Pro Ser Tyr His 
    850                 855                 860                 


His Ser Pro Tyr Lys His Ala His Ile Pro Ala His Ala Gln His Tyr 
865                 870                 875                 880 


Gln Ser Tyr Met Gln Leu Ile Gln Gln Lys Ser Ala Val Glu Tyr Ala 
                885                 890                 895     


Gln Ser Gln Met Ser Leu Val Ser Met Cys Lys Asp Leu Ser Ser Pro 
            900                 905                 910         


Thr Pro Ser Glu Pro Arg Met Glu Trp Lys Val Lys Ile Arg Ser Asp 
        915                 920                 925             


Gly Thr Arg Tyr Ile Thr Lys Arg Pro Val Arg Asp Arg Leu Leu Arg 
    930                 935                 940                 


Glu Arg Ala Leu Lys Ile Arg Glu Glu Arg Ser Gly Met Thr Thr Asp 
945                 950                 955                 960 


Asp Asp Ala Val Ser Glu Met Lys Met Gly Arg Tyr Trp Ser Lys Glu 
                965                 970                 975     


Glu Arg Lys Gln His Leu Val Lys Ala Lys Glu Gln Arg Arg Arg Arg 
            980                 985                 990         


Glu Phe Met Met Gln Ser Arg Leu  Asp Cys Leu Lys Glu  Gln Gln Ala 
        995                 1000                 1005             


Ala Asp  Asp Arg Lys Glu Met  Asn Ile Leu Glu Leu  Ser His Lys 
    1010                 1015                 1020             


Lys Met  Met Lys Lys Arg Asn  Lys Lys Ile Phe Asp  Asn Trp Met 
    1025                 1030                 1035             


Thr Ile  Gln Glu Leu Leu Thr  His Gly Thr Lys Ser  Pro Asp Gly 
    1040                 1045                 1050             


Thr Arg  Val Tyr Asn Ser Phe  Leu Ser Val Thr Thr  Val 
    1055                 1060                 1065     


<210>  1371
<211>  130
<212>  PRT
<213>  Human

<400>  1371

Met Ala Glu Tyr Gly Thr Leu Leu Gln Asp Leu Thr Asn Asn Ile Thr 
1               5                   10                  15      


Leu Glu Asp Leu Glu Gln Leu Lys Ser Ala Cys Lys Glu Asp Ile Pro 
            20                  25                  30          


Ser Glu Lys Ser Glu Glu Ile Thr Thr Gly Ser Ala Trp Phe Ser Phe 
        35                  40                  45              


Leu Glu Ser His Asn Lys Leu Asp Lys Asp Asn Leu Ser Tyr Ile Glu 
    50                  55                  60                  


His Ile Phe Glu Ile Ser Arg Arg Pro Asp Leu Leu Thr Met Val Val 
65                  70                  75                  80  


Asp Tyr Arg Thr Arg Val Leu Lys Ile Ser Glu Glu Asp Glu Leu Asp 
                85                  90                  95      


Thr Lys Leu Thr Arg Ile Pro Ser Ala Lys Lys Tyr Lys Asp Ile Ile 
            100                 105                 110         


Arg Gln Pro Ser Glu Glu Glu Ile Ile Lys Leu Ala Pro Pro Pro Lys 
        115                 120                 125             


Lys Ala 
    130 


<210>  1372
<211>  1290
<212>  PRT
<213>  Human

<400>  1372

Met Ser Gly Pro Leu Glu Gly Ala Asp Gly Gly Gly Asp Pro Arg Pro 
1               5                   10                  15      


Gly Glu Ser Phe Cys Pro Gly Gly Val Pro Ser Pro Gly Pro Pro Gln 
            20                  25                  30          


His Arg Pro Cys Pro Gly Pro Ser Leu Ala Asp Asp Thr Asp Ala Asn 
        35                  40                  45              


Ser Asn Gly Ser Ser Gly Asn Glu Ser Asn Gly His Glu Ser Arg Gly 
    50                  55                  60                  


Ala Ser Gln Arg Ser Ser His Ser Ser Ser Ser Gly Asn Gly Lys Asp 
65                  70                  75                  80  


Ser Ala Leu Leu Glu Thr Thr Glu Ser Ser Lys Ser Thr Asn Ser Gln 
                85                  90                  95      


Ser Pro Ser Pro Pro Ser Ser Ser Ile Ala Tyr Ser Leu Leu Ser Ala 
            100                 105                 110         


Ser Ser Glu Gln Asp Asn Pro Ser Thr Ser Gly Cys Ser Ser Glu Gln 
        115                 120                 125             


Ser Ala Arg Ala Arg Thr Gln Lys Glu Leu Met Thr Ala Leu Arg Glu 
    130                 135                 140                 


Leu Lys Leu Arg Leu Pro Pro Glu Arg Arg Gly Lys Gly Arg Ser Gly 
145                 150                 155                 160 


Thr Leu Ala Thr Leu Gln Tyr Ala Leu Ala Cys Val Lys Gln Val Gln 
                165                 170                 175     


Ala Asn Gln Glu Tyr Tyr Gln Gln Trp Ser Leu Glu Glu Gly Glu Pro 
            180                 185                 190         


Cys Ser Met Asp Met Ser Thr Tyr Thr Leu Glu Glu Leu Glu His Ile 
        195                 200                 205             


Thr Ser Glu Tyr Thr Leu Gln Asn Gln Asp Thr Phe Ser Val Ala Val 
    210                 215                 220                 


Ser Phe Leu Thr Gly Arg Ile Val Tyr Ile Ser Glu Gln Ala Ala Val 
225                 230                 235                 240 


Leu Leu Arg Cys Lys Arg Asp Val Phe Arg Gly Thr Arg Phe Ser Glu 
                245                 250                 255     


Leu Leu Ala Pro Gln Asp Val Gly Val Phe Tyr Gly Ser Thr Ala Pro 
            260                 265                 270         


Ser Arg Leu Pro Thr Trp Gly Thr Gly Ala Ser Ala Gly Ser Gly Leu 
        275                 280                 285             


Arg Asp Phe Thr Gln Glu Lys Ser Val Phe Cys Arg Ile Arg Gly Gly 
    290                 295                 300                 


Pro Asp Arg Asp Pro Gly Pro Arg Tyr Gln Pro Phe Arg Leu Thr Pro 
305                 310                 315                 320 


Tyr Val Thr Lys Ile Arg Val Ser Asp Gly Ala Pro Ala Gln Pro Cys 
                325                 330                 335     


Cys Leu Leu Ile Ala Glu Arg Ile His Ser Gly Tyr Glu Ala Pro Arg 
            340                 345                 350         


Ile Pro Pro Asp Lys Arg Ile Phe Thr Thr Arg His Thr Pro Ser Cys 
        355                 360                 365             


Leu Phe Gln Asp Val Asp Glu Arg Ala Ala Pro Leu Leu Gly Tyr Leu 
    370                 375                 380                 


Pro Gln Asp Leu Leu Gly Ala Pro Val Leu Leu Phe Leu His Pro Glu 
385                 390                 395                 400 


Asp Arg Pro Leu Met Leu Ala Ile His Lys Lys Ile Leu Gln Leu Ala 
                405                 410                 415     


Gly Gln Pro Phe Asp His Ser Pro Ile Arg Phe Cys Ala Arg Asn Gly 
            420                 425                 430         


Glu Tyr Val Thr Met Asp Thr Ser Trp Ala Gly Phe Val His Pro Trp 
        435                 440                 445             


Ser Arg Lys Val Ala Phe Val Leu Gly Arg His Lys Val Arg Thr Ala 
    450                 455                 460                 


Pro Leu Asn Glu Asp Val Phe Thr Pro Pro Ala Pro Ser Pro Ala Pro 
465                 470                 475                 480 


Ser Leu Asp Thr Asp Ile Gln Glu Leu Ser Glu Gln Ile His Arg Leu 
                485                 490                 495     


Leu Leu Gln Pro Val His Ser Pro Ser Pro Thr Gly Leu Cys Gly Val 
            500                 505                 510         


Gly Ala Val Thr Ser Pro Gly Pro Leu His Ser Pro Gly Ser Ser Ser 
        515                 520                 525             


Asp Ser Asn Gly Gly Asp Ala Glu Gly Pro Gly Pro Pro Ala Pro Val 
    530                 535                 540                 


Thr Phe Gln Gln Ile Cys Lys Asp Val His Leu Val Lys His Gln Gly 
545                 550                 555                 560 


Gln Gln Leu Phe Ile Glu Ser Arg Ala Arg Pro Gln Ser Arg Pro Arg 
                565                 570                 575     


Leu Pro Ala Thr Gly Thr Phe Lys Ala Lys Ala Leu Pro Cys Gln Ser 
            580                 585                 590         


Pro Asp Pro Glu Leu Glu Ala Gly Ser Ala Pro Val Gln Ala Pro Leu 
        595                 600                 605             


Ala Leu Val Pro Glu Glu Ala Glu Arg Lys Glu Ala Ser Ser Cys Ser 
    610                 615                 620                 


Tyr Gln Gln Ile Asn Cys Leu Asp Ser Ile Leu Arg Tyr Leu Glu Ser 
625                 630                 635                 640 


Cys Asn Leu Pro Ser Thr Thr Lys Arg Lys Cys Ala Ser Ser Ser Ser 
                645                 650                 655     


Tyr Thr Thr Ser Ser Ala Ser Asp Asp Asp Arg Gln Arg Thr Gly Pro 
            660                 665                 670         


Val Ser Val Gly Thr Lys Lys Asp Pro Pro Ser Ala Ala Leu Ser Gly 
        675                 680                 685             


Glu Gly Ala Thr Pro Arg Lys Glu Pro Val Val Gly Gly Thr Leu Ser 
    690                 695                 700                 


Pro Leu Ala Leu Ala Asn Lys Ala Glu Ser Val Val Ser Val Thr Ser 
705                 710                 715                 720 


Gln Cys Ser Phe Ser Ser Thr Ile Val His Val Gly Asp Lys Lys Pro 
                725                 730                 735     


Pro Glu Ser Asp Ile Ile Met Met Glu Asp Leu Pro Gly Leu Ala Pro 
            740                 745                 750         


Gly Pro Ala Pro Ser Pro Ala Pro Ser Pro Thr Val Ala Pro Asp Pro 
        755                 760                 765             


Ala Pro Asp Ala Tyr Arg Pro Val Gly Leu Thr Lys Ala Val Leu Ser 
    770                 775                 780                 


Leu His Thr Gln Lys Glu Glu Gln Ala Phe Leu Ser Arg Phe Arg Asp 
785                 790                 795                 800 


Leu Gly Arg Leu Arg Gly Leu Asp Ser Ser Ser Thr Ala Pro Ser Ala 
                805                 810                 815     


Leu Gly Glu Arg Gly Cys His His Gly Pro Ala Pro Pro Ser Arg Arg 
            820                 825                 830         


His His Cys Arg Ser Lys Ala Lys Arg Ser Arg His His Gln Asn Pro 
        835                 840                 845             


Arg Ala Glu Ala Pro Cys Tyr Val Ser His Pro Ser Pro Val Pro Pro 
    850                 855                 860                 


Ser Thr Pro Trp Pro Thr Pro Pro Ala Thr Thr Pro Phe Pro Ala Val 
865                 870                 875                 880 


Val Gln Pro Tyr Pro Leu Pro Val Phe Ser Pro Arg Gly Gly Pro Gln 
                885                 890                 895     


Pro Leu Pro Pro Ala Pro Thr Ser Val Pro Pro Ala Ala Phe Pro Ala 
            900                 905                 910         


Pro Leu Val Thr Pro Met Val Ala Leu Val Leu Pro Asn Tyr Leu Phe 
        915                 920                 925             


Pro Thr Pro Ser Ser Tyr Pro Tyr Gly Ala Leu Gln Thr Pro Ala Glu 
    930                 935                 940                 


Gly Pro Pro Thr Pro Ala Ser His Ser Pro Ser Pro Ser Leu Pro Ala 
945                 950                 955                 960 


Leu Ala Pro Ser Pro Pro His Arg Pro Asp Ser Pro Leu Phe Asn Ser 
                965                 970                 975     


Arg Cys Ser Ser Pro Leu Gln Leu Asn Leu Leu Gln Leu Glu Glu Leu 
            980                 985                 990         


Pro Arg Ala Glu Gly Ala Ala Val  Ala Gly Gly Pro Gly  Ser Ser Ala 
        995                 1000                 1005             


Gly Pro  Pro Pro Pro Ser Ala  Glu Ala Ala Glu Pro  Glu Ala Arg 
    1010                 1015                 1020             


Leu Ala  Glu Val Thr Glu Ser  Ser Asn Gln Asp Ala  Leu Ser Gly 
    1025                 1030                 1035             


Ser Ser  Asp Leu Leu Glu Leu  Leu Leu Gln Glu Asp  Ser Arg Ser 
    1040                 1045                 1050             


Gly Thr  Gly Ser Ala Ala Ser  Gly Ser Leu Gly Ser  Gly Leu Gly 
    1055                 1060                 1065             


Ser Gly  Ser Gly Ser Gly Ser  His Glu Gly Gly Ser  Thr Ser Ala 
    1070                 1075                 1080             


Ser Ile  Thr Arg Ser Ser Gln  Ser Ser His Thr Ser  Lys Tyr Phe 
    1085                 1090                 1095             


Gly Ser  Ile Asp Ser Ser Glu  Ala Glu Ala Gly Ala  Ala Arg Gly 
    1100                 1105                 1110             


Gly Ala  Glu Pro Gly Asp Gln  Val Ile Lys Tyr Val  Leu Gln Asp 
    1115                 1120                 1125             


Pro Ile  Trp Leu Leu Met Ala  Asn Ala Asp Gln Arg  Val Met Met 
    1130                 1135                 1140             


Thr Tyr  Gln Val Pro Ser Arg  Asp Met Thr Ser Val  Leu Lys Gln 
    1145                 1150                 1155             


Asp Arg  Glu Arg Leu Arg Ala  Met Gln Lys Gln Gln  Pro Arg Phe 
    1160                 1165                 1170             


Ser Glu  Asp Gln Arg Arg Glu  Leu Gly Ala Val His  Ser Trp Val 
    1175                 1180                 1185             


Arg Lys  Gly Gln Leu Pro Arg  Ala Leu Asp Val Met  Ala Cys Val 
    1190                 1195                 1200             


Asp Cys  Gly Ser Ser Thr Gln  Asp Pro Gly His Pro  Asp Asp Pro 
    1205                 1210                 1215             


Leu Phe  Ser Glu Leu Asp Gly  Leu Gly Leu Glu Pro  Met Glu Glu 
    1220                 1225                 1230             


Gly Gly  Gly Glu Gln Gly Ser  Ser Gly Gly Gly Ser  Gly Glu Gly 
    1235                 1240                 1245             


Glu Gly  Cys Glu Glu Ala Gln  Gly Gly Ala Lys Ala  Ser Ser Ser 
    1250                 1255                 1260             


Gln Asp  Leu Ala Met Glu Glu  Glu Glu Glu Gly Arg  Ser Ser Ser 
    1265                 1270                 1275             


Ser Pro  Ala Leu Pro Thr Ala  Gly Asn Cys Thr Ser  
    1280                 1285                 1290 


<210>  1373
<211>  1004
<212>  PRT
<213>  Human

<400>  1373

Met Trp Glu Lys Met Glu Thr Lys Thr Ile Val Tyr Asp Leu Asp Thr 
1               5                   10                  15      


Ser Gly Gly Leu Met Glu Gln Ile Gln Ala Leu Leu Ala Pro Pro Lys 
            20                  25                  30          


Thr Asp Glu Ala Glu Lys Arg Ser Arg Lys Pro Glu Lys Glu Pro Arg 
        35                  40                  45              


Arg Ser Gly Arg Ala Thr Asn His Asp Ser Cys Asp Ser Cys Lys Glu 
    50                  55                  60                  


Gly Gly Asp Leu Leu Cys Cys Asp His Cys Pro Ala Ala Phe His Leu 
65                  70                  75                  80  


Gln Cys Cys Asn Pro Pro Leu Ser Glu Glu Met Leu Pro Pro Gly Glu 
                85                  90                  95      


Trp Met Cys His Arg Cys Thr Val Arg Arg Lys Lys Arg Glu Gln Lys 
            100                 105                 110         


Lys Glu Leu Gly His Val Asn Gly Leu Val Asp Lys Ser Gly Lys Arg 
        115                 120                 125             


Thr Thr Ser Pro Ser Ser Asp Thr Asp Leu Leu Asp Arg Ser Ala Ser 
    130                 135                 140                 


Lys Thr Glu Leu Lys Ala Ile Ala His Ala Arg Ile Leu Glu Arg Arg 
145                 150                 155                 160 


Ala Ser Arg Pro Gly Thr Pro Thr Ser Ser Ala Ser Thr Glu Thr Pro 
                165                 170                 175     


Thr Ser Glu Gln Asn Asp Val Asp Glu Asp Ile Ile Asp Val Asp Glu 
            180                 185                 190         


Glu Pro Val Ala Ala Glu Pro Asp Tyr Val Gln Pro Gln Leu Arg Arg 
        195                 200                 205             


Pro Phe Glu Leu Leu Ile Ala Ala Ala Met Glu Arg Asn Pro Thr Gln 
    210                 215                 220                 


Phe Gln Leu Pro Asn Glu Leu Thr Cys Thr Thr Ala Leu Pro Gly Ser 
225                 230                 235                 240 


Ser Lys Arg Arg Arg Lys Glu Glu Thr Thr Gly Lys Asn Val Lys Lys 
                245                 250                 255     


Thr Gln His Glu Leu Asp His Asn Gly Leu Val Pro Leu Pro Val Lys 
            260                 265                 270         


Val Cys Phe Thr Cys Asn Arg Ser Cys Arg Val Ala Pro Leu Ile Gln 
        275                 280                 285             


Cys Asp Tyr Cys Pro Leu Leu Phe His Met Asp Cys Leu Glu Pro Pro 
    290                 295                 300                 


Leu Thr Ala Met Pro Leu Gly Arg Trp Met Cys Pro Asn His Ile Glu 
305                 310                 315                 320 


His Val Val Leu Asn Gln Lys Asn Met Thr Leu Ser Asn Arg Cys Gln 
                325                 330                 335     


Val Phe Asp Arg Phe Gln Asp Thr Val Ser Gln His Val Val Lys Val 
            340                 345                 350         


Asp Phe Leu Asn Arg Ile His Lys Lys His Pro Pro Asn Arg Arg Val 
        355                 360                 365             


Leu Gln Ser Val Lys Arg Arg Ser Leu Lys Val Pro Asp Ala Ile Lys 
    370                 375                 380                 


Ser Gln Tyr Gln Phe Pro Pro Pro Leu Ile Ala Pro Ala Ala Ile Arg 
385                 390                 395                 400 


Asp Gly Glu Leu Ile Cys Asn Gly Ile Pro Glu Glu Ser Gln Met His 
                405                 410                 415     


Leu Leu Asn Ser Glu His Leu Ala Thr Gln Ala Glu Gln Gln Glu Trp 
            420                 425                 430         


Leu Cys Ser Val Val Ala Leu Gln Cys Ser Ile Leu Lys His Leu Ser 
        435                 440                 445             


Ala Lys Gln Met Pro Ser His Trp Asp Ser Glu Gln Thr Glu Lys Ala 
    450                 455                 460                 


Asp Ile Lys Pro Val Ile Val Thr Asp Ser Ser Val Thr Thr Ser Leu 
465                 470                 475                 480 


Gln Thr Ala Asp Lys Thr Pro Thr Pro Ser His Tyr Pro Leu Ser Cys 
                485                 490                 495     


Pro Ser Gly Ile Ser Thr Gln Asn Ser Leu Ser Cys Ser Pro Pro His 
            500                 505                 510         


Gln Ser Pro Ala Leu Glu Asp Ile Gly Cys Ser Ser Cys Ala Glu Lys 
        515                 520                 525             


Ser Lys Lys Thr Pro Cys Gly Thr Ala Asn Gly Pro Val Asn Thr Glu 
    530                 535                 540                 


Val Lys Ala Asn Gly Pro His Leu Tyr Ser Ser Pro Thr Asp Ser Thr 
545                 550                 555                 560 


Asp Pro Arg Arg Leu Pro Gly Ala Asn Thr Pro Leu Pro Gly Leu Ser 
                565                 570                 575     


His Arg Gln Gly Trp Pro Arg Pro Leu Thr Pro Pro Ala Ala Gly Gly 
            580                 585                 590         


Leu Gln Asn His Thr Val Gly Ile Ile Val Lys Thr Glu Asn Ala Thr 
        595                 600                 605             


Gly Pro Ser Ser Cys Pro Gln Arg Ser Leu Val Pro Val Pro Ser Leu 
    610                 615                 620                 


Pro Pro Ser Ile Pro Ser Ser Cys Ala Ser Ile Glu Asn Thr Ser Thr 
625                 630                 635                 640 


Leu Gln Arg Lys Thr Val Gln Ser Gln Ile Gly Pro Pro Leu Thr Asp 
                645                 650                 655     


Ser Arg Pro Leu Gly Ser Pro Pro Asn Ala Thr Arg Val Leu Thr Pro 
            660                 665                 670         


Pro Gln Ala Ala Gly Asp Gly Ile Leu Ala Thr Thr Ala Asn Gln Arg 
        675                 680                 685             


Phe Ser Ser Pro Ala Pro Ser Ser Asp Gly Lys Val Ser Pro Gly Thr 
    690                 695                 700                 


Leu Ser Ile Gly Ser Ala Leu Thr Val Pro Ser Phe Pro Ala Asn Ser 
705                 710                 715                 720 


Thr Ala Met Val Asp Leu Thr Asn Ser Leu Arg Ala Phe Met Asp Val 
                725                 730                 735     


Asn Gly Glu Ile Glu Ile Asn Met Leu Asp Glu Lys Leu Ile Lys Phe 
            740                 745                 750         


Leu Ala Leu Gln Arg Ile His Gln Leu Phe Pro Ser Arg Val Gln Pro 
        755                 760                 765             


Ser Pro Gly Ser Val Gly Thr His Gln Leu Ala Ser Gly Gly His His 
    770                 775                 780                 


Ile Glu Val Gln Arg Lys Glu Val Gln Ala Arg Ala Val Phe Tyr Pro 
785                 790                 795                 800 


Leu Leu Gly Leu Gly Gly Ala Val Asn Met Cys Tyr Arg Thr Leu Tyr 
                805                 810                 815     


Ile Gly Thr Gly Ala Asp Met Asp Val Cys Leu Thr Asn Tyr Gly His 
            820                 825                 830         


Cys Asn Tyr Val Ser Gly Lys His Ala Cys Ile Phe Tyr Asp Glu Asn 
        835                 840                 845             


Thr Lys His Tyr Glu Leu Leu Asn Tyr Ser Glu His Gly Thr Thr Val 
    850                 855                 860                 


Asp Asn Val Leu Tyr Ser Cys Asp Phe Ser Glu Lys Thr Pro Pro Thr 
865                 870                 875                 880 


Pro Pro Ser Ser Ile Val Ala Lys Val Gln Ser Val Ile Arg Arg Arg 
                885                 890                 895     


Arg His Gln Lys Gln Asp Glu Glu Pro Ser Glu Glu Ala Ala Met Met 
            900                 905                 910         


Ser Ser Gln Ala Gln Gly Pro Gln Arg Arg Pro Cys Asn Cys Lys Ala 
        915                 920                 925             


Ser Ser Ser Ser Leu Ile Gly Gly Ser Gly Ala Gly Trp Glu Gly Thr 
    930                 935                 940                 


Ala Leu Leu His His Gly Ser Tyr Ile Lys Leu Gly Cys Leu Gln Phe 
945                 950                 955                 960 


Val Phe Ser Ile Thr Glu Phe Ala Thr Lys Gln Pro Lys Gly Asp Ala 
                965                 970                 975     


Ser Leu Leu Gln Asp Gly Val Leu Ala Glu Lys Leu Ser Leu Lys Pro 
            980                 985                 990         


His Gln Gly Pro Val Leu Arg Ser  Asn Ser Val Pro 
        995                 1000                 


<210>  1374
<211>  533
<212>  PRT
<213>  Human

<400>  1374

Met Ala Phe Ala Asn Leu Arg Lys Val Leu Ile Ser Asp Ser Leu Asp 
1               5                   10                  15      


Pro Cys Cys Arg Lys Ile Leu Gln Asp Gly Gly Leu Gln Val Val Glu 
            20                  25                  30          


Lys Gln Asn Leu Ser Lys Glu Glu Leu Ile Ala Glu Leu Gln Asp Cys 
        35                  40                  45              


Glu Gly Leu Ile Val Arg Ser Ala Thr Lys Val Thr Ala Asp Val Ile 
    50                  55                  60                  


Asn Ala Ala Glu Lys Leu Gln Val Val Gly Arg Ala Gly Thr Gly Val 
65                  70                  75                  80  


Asp Asn Val Asp Leu Glu Ala Ala Thr Arg Lys Gly Ile Leu Val Met 
                85                  90                  95      


Asn Thr Pro Asn Gly Asn Ser Leu Ser Ala Ala Glu Leu Thr Cys Gly 
            100                 105                 110         


Met Ile Met Cys Leu Ala Arg Gln Ile Pro Gln Ala Thr Ala Ser Met 
        115                 120                 125             


Lys Asp Gly Lys Trp Glu Arg Lys Lys Phe Met Gly Thr Glu Leu Asn 
    130                 135                 140                 


Gly Lys Thr Leu Gly Ile Leu Gly Leu Gly Arg Ile Gly Arg Glu Val 
145                 150                 155                 160 


Ala Thr Arg Met Gln Ser Phe Gly Met Lys Thr Ile Gly Tyr Asp Pro 
                165                 170                 175     


Ile Ile Ser Pro Glu Val Ser Ala Ser Phe Gly Val Gln Gln Leu Pro 
            180                 185                 190         


Leu Glu Glu Ile Trp Pro Leu Cys Asp Phe Ile Thr Val His Thr Pro 
        195                 200                 205             


Leu Leu Pro Ser Thr Thr Gly Leu Leu Asn Asp Asn Thr Phe Ala Gln 
    210                 215                 220                 


Cys Lys Lys Gly Val Arg Val Val Asn Cys Ala Arg Gly Gly Ile Val 
225                 230                 235                 240 


Asp Glu Gly Ala Leu Leu Arg Ala Leu Gln Ser Gly Gln Cys Ala Gly 
                245                 250                 255     


Ala Ala Leu Asp Val Phe Thr Glu Glu Pro Pro Arg Asp Arg Ala Leu 
            260                 265                 270         


Val Asp His Glu Asn Val Ile Ser Cys Pro His Leu Gly Ala Ser Thr 
        275                 280                 285             


Lys Glu Ala Gln Ser Arg Cys Gly Glu Glu Ile Ala Val Gln Phe Val 
    290                 295                 300                 


Asp Met Val Lys Gly Lys Ser Leu Thr Gly Val Val Asn Ala Gln Ala 
305                 310                 315                 320 


Leu Thr Ser Ala Phe Ser Pro His Thr Lys Pro Trp Ile Gly Leu Ala 
                325                 330                 335     


Glu Ala Leu Gly Thr Leu Met Arg Ala Trp Ala Gly Ser Pro Lys Gly 
            340                 345                 350         


Thr Ile Gln Val Ile Thr Gln Gly Thr Ser Leu Lys Asn Ala Gly Asn 
        355                 360                 365             


Cys Leu Ser Pro Ala Val Ile Val Gly Leu Leu Lys Glu Ala Ser Lys 
    370                 375                 380                 


Gln Ala Asp Val Asn Leu Val Asn Ala Lys Leu Leu Val Lys Glu Ala 
385                 390                 395                 400 


Gly Leu Asn Val Thr Thr Ser His Ser Pro Ala Ala Pro Gly Glu Gln 
                405                 410                 415     


Gly Phe Gly Glu Cys Leu Leu Ala Val Ala Leu Ala Gly Ala Pro Tyr 
            420                 425                 430         


Gln Ala Val Gly Leu Val Gln Gly Thr Thr Pro Val Leu Gln Gly Leu 
        435                 440                 445             


Asn Gly Ala Val Phe Arg Pro Glu Val Pro Leu Arg Arg Asp Leu Pro 
    450                 455                 460                 


Leu Leu Leu Phe Arg Thr Gln Thr Ser Asp Pro Ala Met Leu Pro Thr 
465                 470                 475                 480 


Met Ile Gly Leu Leu Ala Glu Ala Gly Val Arg Leu Leu Ser Tyr Gln 
                485                 490                 495     


Thr Ser Leu Val Ser Asp Gly Glu Thr Trp His Val Met Gly Ile Ser 
            500                 505                 510         


Ser Leu Leu Pro Ser Leu Glu Ala Trp Lys Gln His Val Thr Glu Ala 
        515                 520                 525             


Phe Gln Phe His Phe 
    530             


<210>  1375
<211>  646
<212>  PRT
<213>  Human

<400>  1375

Met Glu Pro Ala Ala Gly Phe Leu Ser Pro Arg Pro Phe Gln Arg Ala 
1               5                   10                  15      


Ala Ala Ala Pro Ala Pro Pro Ala Gly Pro Gly Pro Pro Pro Ser Ala 
            20                  25                  30          


Leu Arg Gly Pro Glu Leu Glu Met Leu Ala Gly Leu Pro Thr Ser Asp 
        35                  40                  45              


Pro Gly Arg Leu Ile Thr Asp Pro Arg Ser Gly Arg Thr Tyr Leu Lys 
    50                  55                  60                  


Gly Arg Leu Leu Gly Lys Gly Gly Phe Ala Arg Cys Tyr Glu Ala Thr 
65                  70                  75                  80  


Asp Thr Glu Thr Gly Ser Ala Tyr Ala Val Lys Val Ile Pro Gln Ser 
                85                  90                  95      


Arg Val Ala Lys Pro His Gln Arg Glu Lys Ile Leu Asn Glu Ile Glu 
            100                 105                 110         


Leu His Arg Asp Leu Gln His Arg His Ile Val Arg Phe Ser His His 
        115                 120                 125             


Phe Glu Asp Ala Asp Asn Ile Tyr Ile Phe Leu Glu Leu Cys Ser Arg 
    130                 135                 140                 


Lys Ser Leu Ala His Ile Trp Lys Ala Arg His Thr Leu Leu Glu Pro 
145                 150                 155                 160 


Glu Val Arg Tyr Tyr Leu Arg Gln Ile Leu Ser Gly Leu Lys Tyr Leu 
                165                 170                 175     


His Gln Arg Gly Ile Leu His Arg Asp Leu Lys Leu Gly Asn Phe Phe 
            180                 185                 190         


Ile Thr Glu Asn Met Glu Leu Lys Val Gly Asp Phe Gly Leu Ala Ala 
        195                 200                 205             


Arg Leu Glu Pro Pro Glu Gln Arg Lys Lys Thr Ile Cys Gly Thr Pro 
    210                 215                 220                 


Asn Tyr Val Ala Pro Glu Val Leu Leu Arg Gln Gly His Gly Pro Glu 
225                 230                 235                 240 


Ala Asp Val Trp Ser Leu Gly Cys Val Met Tyr Thr Leu Leu Cys Gly 
                245                 250                 255     


Ser Pro Pro Phe Glu Thr Ala Asp Leu Lys Glu Thr Tyr Arg Cys Ile 
            260                 265                 270         


Lys Gln Val His Tyr Thr Leu Pro Ala Ser Leu Ser Leu Pro Ala Arg 
        275                 280                 285             


Gln Leu Leu Ala Ala Ile Leu Arg Ala Ser Pro Arg Asp Arg Pro Ser 
    290                 295                 300                 


Ile Asp Gln Ile Leu Arg His Asp Phe Phe Thr Lys Gly Tyr Thr Pro 
305                 310                 315                 320 


Asp Arg Leu Pro Ile Ser Ser Cys Val Thr Val Pro Asp Leu Thr Pro 
                325                 330                 335     


Pro Asn Pro Ala Arg Ser Leu Phe Ala Lys Val Thr Lys Ser Leu Phe 
            340                 345                 350         


Gly Arg Lys Lys Lys Ser Lys Asn His Ala Gln Glu Arg Asp Glu Val 
        355                 360                 365             


Ser Gly Leu Val Ser Gly Leu Met Arg Thr Ser Val Gly His Gln Asp 
    370                 375                 380                 


Ala Arg Pro Glu Ala Pro Ala Ala Ser Gly Pro Ala Pro Val Ser Leu 
385                 390                 395                 400 


Val Glu Thr Ala Pro Glu Asp Ser Ser Pro Arg Gly Thr Leu Ala Ser 
                405                 410                 415     


Ser Gly Asp Gly Phe Glu Glu Gly Leu Thr Val Ala Thr Val Val Glu 
            420                 425                 430         


Ser Ala Leu Cys Ala Leu Arg Asn Cys Ile Ala Phe Met Pro Pro Ala 
        435                 440                 445             


Glu Gln Asn Pro Ala Pro Leu Ala Gln Pro Glu Pro Leu Val Trp Val 
    450                 455                 460                 


Ser Lys Trp Val Asp Tyr Ser Asn Lys Phe Gly Phe Gly Tyr Gln Leu 
465                 470                 475                 480 


Ser Ser Arg Arg Val Ala Val Leu Phe Asn Asp Gly Thr His Met Ala 
                485                 490                 495     


Leu Ser Ala Asn Arg Lys Thr Val His Tyr Asn Pro Thr Ser Thr Lys 
            500                 505                 510         


His Phe Ser Phe Ser Val Gly Ala Val Pro Arg Ala Leu Gln Pro Gln 
        515                 520                 525             


Leu Gly Ile Leu Arg Tyr Phe Ala Ser Tyr Met Glu Gln His Leu Met 
    530                 535                 540                 


Lys Gly Gly Asp Leu Pro Ser Val Glu Glu Val Glu Val Pro Ala Pro 
545                 550                 555                 560 


Pro Leu Leu Leu Gln Trp Val Lys Thr Asp Gln Ala Leu Leu Met Leu 
                565                 570                 575     


Phe Ser Asp Gly Thr Val Gln Val Asn Phe Tyr Gly Asp His Thr Lys 
            580                 585                 590         


Leu Ile Leu Ser Gly Trp Glu Pro Leu Leu Val Thr Phe Val Ala Arg 
        595                 600                 605             


Asn Arg Ser Ala Cys Thr Tyr Leu Ala Ser His Leu Arg Gln Leu Gly 
    610                 615                 620                 


Cys Ser Pro Asp Leu Arg Gln Arg Leu Arg Tyr Ala Leu Arg Leu Leu 
625                 630                 635                 640 


Arg Asp Arg Ser Pro Ala 
                645     


<210>  1376
<211>  1838
<212>  PRT
<213>  Human

<400>  1376

Met Ala Leu Gln Leu Trp Ala Leu Thr Leu Leu Gly Leu Leu Gly Ala 
1               5                   10                  15      


Gly Ala Ser Leu Arg Pro Arg Lys Leu Asp Phe Phe Arg Ser Glu Lys 
            20                  25                  30          


Glu Leu Asn His Leu Ala Val Asp Glu Ala Ser Gly Val Val Tyr Leu 
        35                  40                  45              


Gly Ala Val Asn Ala Leu Tyr Gln Leu Asp Ala Lys Leu Gln Leu Glu 
    50                  55                  60                  


Gln Gln Val Ala Thr Gly Pro Ala Leu Asp Asn Lys Lys Cys Thr Pro 
65                  70                  75                  80  


Pro Ile Glu Ala Ser Gln Cys His Glu Ala Glu Met Thr Asp Asn Val 
                85                  90                  95      


Asn Gln Leu Leu Leu Leu Asp Pro Pro Arg Lys Arg Leu Val Glu Cys 
            100                 105                 110         


Gly Ser Leu Phe Lys Gly Ile Cys Ala Leu Arg Ala Leu Ser Asn Ile 
        115                 120                 125             


Ser Leu Arg Leu Phe Tyr Glu Asp Gly Ser Gly Glu Lys Ser Phe Val 
    130                 135                 140                 


Ala Ser Asn Asp Glu Gly Val Ala Thr Val Gly Leu Val Ser Ser Thr 
145                 150                 155                 160 


Gly Pro Gly Gly Asp Arg Val Leu Phe Val Gly Lys Gly Asn Gly Pro 
                165                 170                 175     


His Asp Asn Gly Ile Ile Val Ser Thr Arg Leu Leu Asp Arg Thr Asp 
            180                 185                 190         


Ser Arg Glu Ala Phe Glu Ala Tyr Thr Asp His Ala Thr Tyr Lys Ala 
        195                 200                 205             


Gly Tyr Leu Ser Thr Asn Thr Gln Gln Phe Val Ala Ala Phe Glu Asp 
    210                 215                 220                 


Gly Pro Tyr Val Phe Phe Val Phe Asn Gln Gln Asp Lys His Pro Ala 
225                 230                 235                 240 


Arg Asn Arg Thr Leu Leu Ala Arg Met Cys Arg Glu Asp Pro Asn Tyr 
                245                 250                 255     


Tyr Ser Tyr Leu Glu Met Asp Leu Gln Cys Arg Asp Pro Asp Ile His 
            260                 265                 270         


Ala Ala Ala Phe Gly Thr Cys Leu Ala Ala Ser Val Ala Ala Pro Gly 
        275                 280                 285             


Ser Gly Arg Val Leu Tyr Ala Val Phe Ser Arg Asp Ser Arg Ser Ser 
    290                 295                 300                 


Gly Gly Pro Gly Ala Gly Leu Cys Leu Phe Pro Leu Asp Lys Val His 
305                 310                 315                 320 


Ala Lys Met Glu Ala Asn Arg Asn Ala Cys Tyr Thr Gly Thr Arg Glu 
                325                 330                 335     


Ala Arg Asp Ile Phe Tyr Lys Pro Phe His Gly Asp Ile Gln Cys Gly 
            340                 345                 350         


Gly His Ala Pro Gly Ser Ser Lys Ser Phe Pro Cys Gly Ser Glu His 
        355                 360                 365             


Leu Pro Tyr Pro Leu Gly Ser Arg Asp Gly Leu Arg Gly Thr Ala Val 
    370                 375                 380                 


Leu Gln Arg Gly Gly Leu Asn Leu Thr Ala Val Thr Val Ala Ala Glu 
385                 390                 395                 400 


Asn Asn His Thr Val Ala Phe Leu Gly Thr Ser Asp Gly Arg Ile Leu 
                405                 410                 415     


Lys Val Tyr Leu Thr Pro Asp Gly Thr Ser Ser Glu Tyr Asp Ser Ile 
            420                 425                 430         


Leu Val Glu Ile Asn Lys Arg Val Lys Arg Asp Leu Val Leu Ser Gly 
        435                 440                 445             


Asp Leu Gly Ser Leu Tyr Ala Met Thr Gln Asp Lys Val Phe Arg Leu 
    450                 455                 460                 


Pro Val Gln Glu Cys Leu Ser Tyr Pro Thr Cys Thr Gln Cys Arg Asp 
465                 470                 475                 480 


Ser Gln Asp Pro Tyr Cys Gly Trp Cys Val Val Glu Gly Arg Cys Thr 
                485                 490                 495     


Arg Lys Ala Glu Cys Pro Arg Ala Glu Glu Ala Ser His Trp Leu Trp 
            500                 505                 510         


Ser Arg Ser Lys Ser Cys Val Ala Val Thr Ser Ala Gln Pro Gln Asn 
        515                 520                 525             


Met Ser Arg Arg Ala Gln Gly Glu Val Gln Leu Thr Val Ser Pro Leu 
    530                 535                 540                 


Pro Ala Leu Ser Glu Glu Asp Glu Leu Leu Cys Leu Phe Gly Glu Ser 
545                 550                 555                 560 


Pro Pro His Pro Ala Arg Val Glu Gly Glu Ala Val Ile Cys Asn Ser 
                565                 570                 575     


Pro Ser Ser Ile Pro Val Thr Pro Pro Gly Gln Asp His Val Ala Val 
            580                 585                 590         


Thr Ile Gln Leu Leu Leu Arg Arg Gly Asn Ile Phe Leu Thr Ser Tyr 
        595                 600                 605             


Gln Tyr Pro Phe Tyr Asp Cys Arg Gln Ala Met Ser Leu Glu Glu Asn 
    610                 615                 620                 


Leu Pro Cys Ile Ser Cys Val Ser Asn Arg Trp Thr Cys Gln Trp Asp 
625                 630                 635                 640 


Leu Arg Tyr His Glu Cys Arg Glu Ala Ser Pro Asn Pro Glu Asp Gly 
                645                 650                 655     


Ile Val Arg Ala His Met Glu Asp Ser Cys Pro Gln Phe Leu Gly Pro 
            660                 665                 670         


Ser Pro Leu Val Ile Pro Met Asn His Glu Thr Asp Val Asn Phe Gln 
        675                 680                 685             


Gly Lys Asn Leu Asp Thr Val Lys Gly Ser Ser Leu His Val Gly Ser 
    690                 695                 700                 


Asp Leu Leu Lys Phe Met Glu Pro Val Thr Met Gln Glu Ser Gly Thr 
705                 710                 715                 720 


Phe Ala Phe Arg Thr Pro Lys Leu Ser His Asp Ala Asn Glu Thr Leu 
                725                 730                 735     


Pro Leu His Leu Tyr Val Lys Ser Tyr Gly Lys Asn Ile Asp Ser Lys 
            740                 745                 750         


Leu His Val Thr Leu Tyr Asn Cys Ser Phe Gly Arg Ser Asp Cys Ser 
        755                 760                 765             


Leu Cys Arg Ala Ala Asn Pro Asp Tyr Arg Cys Ala Trp Cys Gly Gly 
    770                 775                 780                 


Gln Ser Arg Cys Val Tyr Glu Ala Leu Cys Asn Thr Thr Ser Glu Cys 
785                 790                 795                 800 


Pro Pro Pro Val Ile Thr Arg Ile Gln Pro Glu Thr Gly Pro Leu Gly 
                805                 810                 815     


Gly Gly Ile Arg Ile Thr Ile Leu Gly Ser Asn Leu Gly Val Gln Ala 
            820                 825                 830         


Gly Asp Ile Gln Arg Ile Ser Val Ala Gly Arg Asn Cys Ser Phe Gln 
        835                 840                 845             


Pro Glu Arg Tyr Ser Val Ser Thr Arg Ile Val Cys Val Ile Glu Ala 
    850                 855                 860                 


Ala Glu Thr Pro Phe Thr Gly Gly Val Glu Val Asp Val Phe Gly Lys 
865                 870                 875                 880 


Leu Gly Arg Ser Pro Pro Asn Val Gln Phe Thr Phe Gln Gln Pro Lys 
                885                 890                 895     


Pro Leu Ser Val Glu Pro Gln Gln Gly Pro Gln Ala Gly Gly Thr Thr 
            900                 905                 910         


Leu Thr Ile His Gly Thr His Leu Asp Thr Gly Ser Gln Glu Asp Val 
        915                 920                 925             


Arg Val Thr Leu Asn Gly Val Pro Cys Lys Val Thr Lys Phe Gly Ala 
    930                 935                 940                 


Gln Leu Gln Cys Val Thr Gly Pro Gln Ala Thr Arg Gly Gln Met Leu 
945                 950                 955                 960 


Leu Glu Val Ser Tyr Gly Gly Ser Pro Val Pro Asn Pro Gly Ile Phe 
                965                 970                 975     


Phe Thr Tyr Arg Glu Asn Pro Val Leu Arg Ala Phe Glu Pro Leu Arg 
            980                 985                 990         


Ser Phe Ala Ser Gly Gly Arg Ser  Ile Asn Val Thr Gly  Gln Gly Phe 
        995                 1000                 1005             


Ser Leu  Ile Gln Arg Phe Ala  Met Val Val Ile Ala  Glu Pro Leu 
    1010                 1015                 1020             


Gln Ser  Trp Gln Pro Pro Arg  Glu Ala Glu Ser Leu  Gln Pro Met 
    1025                 1030                 1035             


Thr Val  Val Gly Thr Asp Tyr  Val Phe His Asn Asp  Thr Lys Val 
    1040                 1045                 1050             


Val Phe  Leu Ser Pro Ala Val  Pro Glu Glu Pro Glu  Ala Tyr Asn 
    1055                 1060                 1065             


Leu Thr  Val Leu Ile Glu Met  Asp Gly His Arg Ala  Leu Leu Arg 
    1070                 1075                 1080             


Thr Glu  Ala Gly Ala Phe Glu  Tyr Val Pro Asp Pro  Thr Phe Glu 
    1085                 1090                 1095             


Asn Phe  Thr Gly Gly Val Lys  Lys Gln Val Asn Lys  Leu Ile His 
    1100                 1105                 1110             


Ala Arg  Gly Thr Asn Leu Asn  Lys Ala Met Thr Leu  Gln Glu Ala 
    1115                 1120                 1125             


Glu Ala  Phe Val Gly Ala Glu  Arg Cys Thr Met Lys  Thr Leu Thr 
    1130                 1135                 1140             


Glu Thr  Asp Leu Tyr Cys Glu  Pro Pro Glu Val Gln  Pro Pro Pro 
    1145                 1150                 1155             


Lys Arg  Arg Gln Lys Arg Asp  Thr Thr His Asn Leu  Pro Glu Phe 
    1160                 1165                 1170             


Ile Val  Lys Phe Gly Ser Arg  Glu Trp Val Leu Gly  Arg Val Glu 
    1175                 1180                 1185             


Tyr Asp  Thr Arg Val Ser Asp  Val Pro Leu Ser Leu  Ile Leu Pro 
    1190                 1195                 1200             


Leu Val  Ile Val Pro Met Val  Val Val Ile Ala Val  Ser Val Tyr 
    1205                 1210                 1215             


Cys Tyr  Trp Arg Lys Ser Gln  Gln Ala Glu Arg Glu  Tyr Glu Lys 
    1220                 1225                 1230             


Ile Lys  Ser Gln Leu Glu Gly  Leu Glu Glu Ser Val  Arg Asp Arg 
    1235                 1240                 1245             


Cys Lys  Lys Glu Phe Thr Asp  Leu Met Ile Glu Met  Glu Asp Gln 
    1250                 1255                 1260             


Thr Asn  Asp Val His Glu Ala  Gly Ile Pro Val Leu  Asp Tyr Lys 
    1265                 1270                 1275             


Thr Tyr  Thr Asp Arg Val Phe  Phe Leu Pro Ser Lys  Asp Gly Asp 
    1280                 1285                 1290             


Lys Asp  Val Met Ile Thr Gly  Lys Leu Asp Ile Pro  Glu Pro Arg 
    1295                 1300                 1305             


Arg Pro  Val Val Glu Gln Ala  Leu Tyr Gln Phe Ser  Asn Leu Leu 
    1310                 1315                 1320             


Asn Ser  Lys Ser Phe Leu Ile  Asn Phe Ile His Thr  Leu Glu Asn 
    1325                 1330                 1335             


Gln Arg  Glu Phe Ser Ala Arg  Ala Lys Val Tyr Phe  Ala Ser Leu 
    1340                 1345                 1350             


Leu Thr  Val Ala Leu His Gly  Lys Leu Glu Tyr Tyr  Thr Asp Ile 
    1355                 1360                 1365             


Met His  Thr Leu Phe Leu Glu  Leu Leu Glu Gln Tyr  Val Val Ala 
    1370                 1375                 1380             


Lys Asn  Pro Lys Leu Met Leu  Arg Arg Ser Glu Thr  Val Val Glu 
    1385                 1390                 1395             


Arg Met  Leu Ser Asn Trp Met  Ser Ile Cys Leu Tyr  Gln Tyr Leu 
    1400                 1405                 1410             


Lys Asp  Ser Ala Gly Glu Pro  Leu Tyr Lys Leu Phe  Lys Ala Ile 
    1415                 1420                 1425             


Lys His  Gln Val Glu Lys Gly  Pro Val Asp Ala Val  Gln Lys Lys 
    1430                 1435                 1440             


Ala Lys  Tyr Thr Leu Asn Asp  Thr Gly Leu Leu Gly  Asp Asp Val 
    1445                 1450                 1455             


Glu Tyr  Ala Pro Leu Thr Val  Ser Val Ile Val Gln  Asp Glu Gly 
    1460                 1465                 1470             


Val Asp  Ala Ile Pro Val Lys  Val Leu Asn Cys Asp  Thr Ile Ser 
    1475                 1480                 1485             


Gln Val  Lys Glu Lys Ile Ile  Asp Gln Val Tyr Arg  Gly Gln Pro 
    1490                 1495                 1500             


Cys Ser  Cys Trp Pro Arg Pro  Asp Ser Val Val Leu  Glu Trp Arg 
    1505                 1510                 1515             


Pro Gly  Ser Thr Ala Gln Ile  Leu Ser Asp Leu Asp  Leu Thr Ser 
    1520                 1525                 1530             


Gln Arg  Glu Gly Arg Trp Lys  Arg Val Asn Thr Leu  Met His Tyr 
    1535                 1540                 1545             


Asn Val  Arg Asp Gly Ala Thr  Leu Ile Leu Ser Lys  Val Gly Val 
    1550                 1555                 1560             


Ser Gln  Gln Pro Glu Asp Ser  Gln Gln Asp Leu Pro  Gly Glu Arg 
    1565                 1570                 1575             


His Ala  Leu Leu Glu Glu Glu  Asn Arg Val Trp His  Leu Val Arg 
    1580                 1585                 1590             


Pro Thr  Asp Glu Val Asp Glu  Gly Lys Ser Lys Arg  Gly Ser Val 
    1595                 1600                 1605             


Lys Glu  Lys Glu Arg Thr Lys  Ala Ile Thr Glu Ile  Tyr Leu Thr 
    1610                 1615                 1620             


Arg Leu  Leu Ser Val Lys Gly  Thr Leu Gln Gln Phe  Val Asp Asn 
    1625                 1630                 1635             


Phe Phe  Gln Ser Val Leu Ala  Pro Gly His Ala Val  Pro Pro Ala 
    1640                 1645                 1650             


Val Lys  Tyr Phe Phe Asp Phe  Leu Asp Glu Gln Ala  Glu Lys His 
    1655                 1660                 1665             


Asn Ile  Gln Asp Glu Asp Thr  Ile His Ile Trp Lys  Thr Asn Ser 
    1670                 1675                 1680             


Leu Pro  Leu Arg Phe Trp Val  Asn Ile Leu Lys Asn  Pro His Phe 
    1685                 1690                 1695             


Ile Phe  Asp Val His Val His  Glu Val Val Asp Ala  Ser Leu Ser 
    1700                 1705                 1710             


Val Ile  Ala Gln Thr Phe Met  Asp Ala Cys Thr Arg  Thr Glu His 
    1715                 1720                 1725             


Lys Leu  Ser Arg Asp Ser Pro  Ser Asn Lys Leu Leu  Tyr Ala Lys 
    1730                 1735                 1740             


Glu Ile  Ser Thr Tyr Lys Lys  Met Val Glu Asp Tyr  Tyr Lys Gly 
    1745                 1750                 1755             


Ile Arg  Gln Met Val Gln Val  Ser Asp Gln Asp Met  Asn Thr His 
    1760                 1765                 1770             


Leu Ala  Glu Ile Ser Arg Ala  His Thr Asp Ser Leu  Asn Thr Leu 
    1775                 1780                 1785             


Val Ala  Leu His Gln Leu Tyr  Gln Tyr Thr Gln Lys  Tyr Tyr Asp 
    1790                 1795                 1800             


Glu Ile  Ile Asn Ala Leu Glu  Glu Asp Pro Ala Ala  Gln Lys Met 
    1805                 1810                 1815             


Gln Leu  Ala Phe Arg Leu Gln  Gln Ile Ala Ala Ala  Leu Glu Asn 
    1820                 1825                 1830             


Lys Val  Thr Asp Leu 
    1835             


<210>  1377
<211>  252
<212>  PRT
<213>  Human

<400>  1377

Met Glu Ser Glu Met Glu Thr Gln Ser Ala Arg Ala Glu Glu Gly Phe 
1               5                   10                  15      


Thr Gln Val Thr Arg Lys Gly Gly Arg Arg Ala Lys Lys Arg Gln Ala 
            20                  25                  30          


Glu Gln Leu Ser Ala Ala Gly Glu Gly Gly Asp Ala Gly Arg Met Asp 
        35                  40                  45              


Thr Glu Glu Ala Arg Pro Ala Lys Arg Pro Val Phe Pro Pro Leu Cys 
    50                  55                  60                  


Gly Asp Gly Leu Leu Ser Gly Lys Glu Glu Thr Arg Lys Ile Pro Val 
65                  70                  75                  80  


Pro Ala Asn Arg Tyr Thr Pro Leu Lys Glu Asn Trp Met Lys Ile Phe 
                85                  90                  95      


Thr Pro Ile Val Glu His Leu Gly Leu Gln Ile Arg Phe Asn Leu Lys 
            100                 105                 110         


Ser Arg Asn Val Glu Ile Arg Thr Cys Lys Glu Thr Lys Asp Val Ser 
        115                 120                 125             


Ala Leu Thr Lys Ala Ala Asp Phe Val Lys Ala Phe Ile Leu Gly Phe 
    130                 135                 140                 


Gln Val Glu Asp Ala Leu Ala Leu Ile Arg Leu Asp Asp Leu Phe Leu 
145                 150                 155                 160 


Glu Ser Phe Glu Ile Thr Asp Val Lys Pro Leu Lys Gly Asp His Leu 
                165                 170                 175     


Ser Arg Ala Ile Gly Arg Ile Ala Gly Lys Gly Gly Lys Thr Lys Phe 
            180                 185                 190         


Thr Ile Glu Asn Val Thr Arg Thr Arg Ile Val Leu Ala Asp Val Lys 
        195                 200                 205             


Val His Ile Leu Gly Ser Phe Gln Asn Ile Lys Met Ala Arg Thr Ala 
    210                 215                 220                 


Ile Cys Asn Leu Ile Leu Gly Asn Pro Pro Ser Lys Val Tyr Gly Asn 
225                 230                 235                 240 


Ile Arg Ala Val Ala Ser Arg Ser Ala Asp Arg Phe 
                245                 250         


<210>  1378
<211>  216
<212>  PRT
<213>  Human

<400>  1378

Met Leu Arg Leu Ser Glu Arg Asn Met Lys Val Leu Leu Ala Ala Ala 
1               5                   10                  15      


Leu Ile Ala Gly Ser Val Phe Phe Leu Leu Leu Pro Gly Pro Ser Ala 
            20                  25                  30          


Ala Asp Glu Lys Lys Lys Gly Pro Lys Val Thr Val Lys Val Tyr Phe 
        35                  40                  45              


Asp Leu Arg Ile Gly Asp Glu Asp Val Gly Arg Val Ile Phe Gly Leu 
    50                  55                  60                  


Phe Gly Lys Thr Val Pro Lys Thr Val Asp Asn Phe Val Ala Leu Ala 
65                  70                  75                  80  


Thr Gly Glu Lys Gly Phe Gly Tyr Lys Asn Ser Lys Phe His Arg Val 
                85                  90                  95      


Ile Lys Asp Phe Met Ile Gln Gly Gly Asp Phe Thr Arg Gly Asp Gly 
            100                 105                 110         


Thr Gly Gly Lys Ser Ile Tyr Gly Glu Arg Phe Pro Asp Glu Asn Phe 
        115                 120                 125             


Lys Leu Lys His Tyr Gly Pro Gly Trp Val Ser Met Ala Asn Ala Gly 
    130                 135                 140                 


Lys Asp Thr Asn Gly Ser Gln Phe Phe Ile Thr Thr Val Lys Thr Ala 
145                 150                 155                 160 


Trp Leu Asp Gly Lys His Val Val Phe Gly Lys Val Leu Glu Gly Met 
                165                 170                 175     


Glu Val Val Arg Lys Val Glu Ser Thr Lys Thr Asp Ser Arg Asp Lys 
            180                 185                 190         


Pro Leu Lys Asp Val Ile Ile Ala Asp Cys Gly Lys Ile Glu Val Glu 
        195                 200                 205             


Lys Pro Phe Ala Ile Ala Lys Glu 
    210                 215     


<210>  1379
<211>  689
<212>  PRT
<213>  Human

<400>  1379

Met Glu Asp Thr Gly Ile Gln Arg Gly Ile Trp Asp Gly Asp Ala Lys 
1               5                   10                  15      


Ala Val Gln Gln Cys Leu Thr Asp Ile Phe Thr Ser Val Tyr Thr Thr 
            20                  25                  30          


Cys Asp Ile Pro Glu Asn Ala Ile Phe Gly Pro Cys Val Leu Ser His 
        35                  40                  45              


Thr Ser Leu Tyr Asp Ser Ile Ala Phe Ile Ala Leu Lys Ser Thr Asp 
    50                  55                  60                  


Lys Arg Thr Val Pro Tyr Ile Phe Arg Val Asp Thr Ser Ala Ala Asn 
65                  70                  75                  80  


Gly Ser Ser Glu Gly Leu Met Trp Leu Arg Leu Val Gln Ser Ala Arg 
                85                  90                  95      


Asp Lys Glu Glu Gln Asn Leu Glu Ala Tyr Ile Lys Asn Gly Gln Leu 
            100                 105                 110         


Phe Tyr Arg Ser Leu Arg Arg Ile Ala Lys Asp Glu Glu Leu Leu Val 
        115                 120                 125             


Trp Tyr Gly Lys Glu Leu Thr Glu Leu Leu Leu Leu Cys Pro Ser Arg 
    130                 135                 140                 


Ser His Asn Lys Met Asn Gly Ser Ser Pro Tyr Thr Cys Leu Glu Cys 
145                 150                 155                 160 


Ser Gln Arg Phe Gln Phe Glu Phe Pro Tyr Val Ala His Leu Arg Phe 
                165                 170                 175     


Arg Cys Pro Lys Arg Leu His Ser Ala Asp Ile Ser Pro Gln Asp Glu 
            180                 185                 190         


Gln Gly Gly Gly Val Gly Thr Lys Asp His Gly Gly Gly Gly Gly Gly 
        195                 200                 205             


Gly Lys Asp Gln Gln Gln Gln Gln Gln Glu Ala Pro Leu Gly Pro Gly 
    210                 215                 220                 


Pro Lys Phe Cys Lys Ala Gly Pro Leu His His Tyr Pro Ser Pro Ser 
225                 230                 235                 240 


Pro Glu Ser Ser Asn Pro Ser Ala Ala Ala Gly Gly Ser Ser Ala Lys 
                245                 250                 255     


Pro Ser Thr Asp Phe His Asn Leu Ala Arg Glu Leu Glu Asn Ser Arg 
            260                 265                 270         


Gly Gly Ser Ser Cys Ser Pro Ala Gln Ser Leu Ser Ser Gly Ser Gly 
        275                 280                 285             


Ser Gly Gly Gly Gly Gly His Gln Glu Ala Glu Leu Ser Pro Asp Gly 
    290                 295                 300                 


Ile Ala Thr Gly Gly Gly Lys Gly Lys Arg Lys Phe Pro Glu Glu Ala 
305                 310                 315                 320 


Ala Glu Gly Gly Gly Gly Ala Gly Leu Val Gly Gly Arg Gly Arg Phe 
                325                 330                 335     


Val Glu Arg Pro Leu Pro Ala Ser Lys Glu Asp Leu Val Cys Thr Pro 
            340                 345                 350         


Gln Gln Tyr Arg Ala Ser Gly Ser Tyr Phe Gly Leu Glu Glu Asn Gly 
        355                 360                 365             


Arg Leu Phe Ala Pro Pro Ser Pro Glu Thr Gly Glu Ala Lys Arg Ser 
    370                 375                 380                 


Ala Phe Val Glu Val Lys Lys Ala Ala Arg Ala Ala Ser Leu Gln Glu 
385                 390                 395                 400 


Glu Gly Thr Ala Asp Gly Ala Gly Val Ala Ser Glu Asp Gln Asp Ala 
                405                 410                 415     


Gly Gly Gly Gly Gly Ser Ser Thr Pro Ala Ala Ala Ser Pro Val Gly 
            420                 425                 430         


Ala Glu Lys Leu Leu Ala Pro Arg Pro Gly Gly Pro Leu Pro Ser Arg 
        435                 440                 445             


Leu Glu Gly Gly Ser Pro Ala Arg Gly Ser Ala Phe Thr Ser Val Pro 
    450                 455                 460                 


Gln Leu Gly Ser Ala Gly Ser Thr Ser Gly Gly Gly Gly Thr Gly Ala 
465                 470                 475                 480 


Gly Ala Ala Gly Gly Ala Gly Gly Gly Gln Gly Ala Ala Ser Asp Glu 
                485                 490                 495     


Arg Lys Ser Ala Phe Ser Gln Pro Ala Arg Ser Phe Ser Gln Leu Ser 
            500                 505                 510         


Pro Leu Val Leu Gly Gln Lys Leu Gly Ala Leu Glu Pro Cys His Pro 
        515                 520                 525             


Ala Asp Gly Val Gly Pro Thr Arg Leu Tyr Pro Ala Ala Ala Asp Pro 
    530                 535                 540                 


Leu Ala Val Lys Leu Gln Gly Ala Ala Asp Leu Asn Gly Gly Cys Gly 
545                 550                 555                 560 


Ser Leu Pro Ser Gly Gly Gly Gly Leu Pro Lys Gln Ser Pro Phe Leu 
                565                 570                 575     


Tyr Ala Thr Ala Phe Trp Pro Lys Ser Ser Ala Ala Ala Ala Ala Ala 
            580                 585                 590         


Ala Ala Ala Ala Ala Ala Gly Pro Leu Gln Leu Gln Leu Pro Ser Ala 
        595                 600                 605             


Leu Thr Leu Leu Pro Pro Ser Phe Thr Ser Leu Cys Leu Pro Ala Gln 
    610                 615                 620                 


Asn Trp Cys Ala Lys Cys Asn Ala Ser Phe Arg Met Thr Ser Asp Leu 
625                 630                 635                 640 


Val Tyr His Met Arg Ser His His Lys Lys Glu Tyr Ala Met Glu Pro 
                645                 650                 655     


Leu Val Lys Arg Arg Arg Glu Glu Lys Leu Lys Cys Pro Ile Cys Asn 
            660                 665                 670         


Glu Ser Phe Arg Glu Arg His His Leu Ser Arg His Met Thr Ser His 
        675                 680                 685             


Asn 
    


<210>  1380
<211>  546
<212>  PRT
<213>  Human

<400>  1380

Met Ala Asn Asn Ser Pro Ala Leu Thr Gly Asn Ser Gln Pro Gln His 
1               5                   10                  15      


Gln Ala Ala Ala Ala Ala Ala Gln Gln Gln Gln Gln Cys Gly Gly Gly 
            20                  25                  30          


Gly Ala Thr Lys Pro Ala Val Ser Gly Lys Gln Gly Asn Val Leu Pro 
        35                  40                  45              


Leu Trp Gly Asn Glu Lys Thr Met Asn Leu Asn Pro Met Ile Leu Thr 
    50                  55                  60                  


Asn Ile Leu Ser Ser Pro Tyr Phe Lys Val Gln Leu Tyr Glu Leu Lys 
65                  70                  75                  80  


Thr Tyr His Glu Val Val Asp Glu Ile Tyr Phe Lys Val Thr His Val 
                85                  90                  95      


Glu Pro Trp Glu Lys Gly Ser Arg Lys Thr Ala Gly Gln Thr Gly Met 
            100                 105                 110         


Cys Gly Gly Val Arg Gly Val Gly Thr Gly Gly Ile Val Ser Thr Ala 
        115                 120                 125             


Phe Cys Leu Leu Tyr Lys Leu Phe Thr Leu Lys Leu Thr Arg Lys Gln 
    130                 135                 140                 


Val Met Gly Leu Ile Thr His Thr Asp Ser Pro Tyr Ile Arg Ala Leu 
145                 150                 155                 160 


Gly Phe Met Tyr Ile Arg Tyr Thr Gln Pro Pro Thr Asp Leu Trp Asp 
                165                 170                 175     


Trp Phe Glu Ser Phe Leu Asp Asp Glu Glu Asp Leu Asp Val Lys Ala 
            180                 185                 190         


Gly Gly Gly Cys Val Met Thr Ile Gly Glu Met Leu Arg Ser Phe Leu 
        195                 200                 205             


Thr Lys Leu Glu Trp Phe Ser Thr Leu Phe Pro Arg Ile Pro Val Pro 
    210                 215                 220                 


Val Gln Lys Asn Ile Asp Gln Gln Ile Lys Thr Arg Pro Arg Lys Ile 
225                 230                 235                 240 


Lys Lys Asp Gly Lys Glu Gly Ala Glu Glu Ile Asp Arg His Val Glu 
                245                 250                 255     


Arg Arg Arg Ser Arg Ser Pro Arg Arg Ser Leu Ser Pro Arg Arg Ser 
            260                 265                 270         


Pro Arg Arg Ser Arg Ser Arg Ser His His Arg Glu Gly His Gly Ser 
        275                 280                 285             


Ser Ser Phe Asp Arg Glu Leu Glu Arg Glu Lys Glu Arg Gln Arg Leu 
    290                 295                 300                 


Glu Arg Glu Ala Lys Glu Arg Glu Lys Glu Arg Arg Arg Ser Arg Ser 
305                 310                 315                 320 


Ile Asp Arg Gly Leu Glu Arg Arg Arg Ser Arg Ser Arg Glu Arg His 
                325                 330                 335     


Arg Ser Arg Ser Arg Ser Arg Asp Arg Lys Gly Asp Arg Arg Asp Arg 
            340                 345                 350         


Asp Arg Glu Arg Glu Lys Glu Asn Glu Arg Gly Arg Arg Arg Asp Arg 
        355                 360                 365             


Asp Tyr Asp Lys Glu Arg Gly Asn Glu Arg Glu Lys Glu Arg Glu Arg 
    370                 375                 380                 


Ser Arg Glu Arg Ser Lys Glu Gln Arg Ser Arg Gly Glu Val Glu Glu 
385                 390                 395                 400 


Lys Lys His Lys Glu Asp Lys Asp Asp Arg Arg His Arg Asp Asp Lys 
                405                 410                 415     


Arg Asp Ser Lys Lys Glu Lys Lys His Ser Arg Ser Arg Ser Arg Glu 
            420                 425                 430         


Arg Lys His Arg Ser Arg Ser Arg Ser Arg Asn Ala Gly Lys Arg Ser 
        435                 440                 445             


Arg Ser Arg Ser Lys Glu Lys Ser Ser Lys His Lys Asn Glu Ser Lys 
    450                 455                 460                 


Glu Lys Ser Asn Lys Arg Ser Arg Ser Gly Ser Gln Gly Arg Thr Asp 
465                 470                 475                 480 


Ser Val Glu Lys Ser Lys Lys Arg Glu His Ser Pro Ser Lys Glu Lys 
                485                 490                 495     


Ser Arg Lys Arg Ser Arg Ser Lys Glu Arg Ser His Lys Arg Asp His 
            500                 505                 510         


Ser Asp Ser Lys Asp Gln Ser Asp Lys His Asp Arg Arg Arg Ser Gln 
        515                 520                 525             


Ser Ile Glu Gln Glu Ser Gln Glu Lys Gln His Lys Asn Lys Asp Glu 
    530                 535                 540                 


Thr Val 
545     


<210>  1381
<211>  168
<212>  PRT
<213>  Human

<400>  1381

Met Gln Ala Gln Gln Tyr Gln Gln Gln Arg Arg Lys Phe Ala Ala Ala 
1               5                   10                  15      


Phe Leu Ala Phe Ile Phe Ile Leu Ala Ala Val Asp Thr Ala Glu Ala 
            20                  25                  30          


Gly Lys Lys Glu Lys Pro Glu Lys Lys Val Lys Lys Ser Asp Cys Gly 
        35                  40                  45              


Glu Trp Gln Trp Ser Val Cys Val Pro Thr Ser Gly Asp Cys Gly Leu 
    50                  55                  60                  


Gly Thr Arg Glu Gly Thr Arg Thr Gly Ala Glu Cys Lys Gln Thr Met 
65                  70                  75                  80  


Lys Thr Gln Arg Cys Lys Ile Pro Cys Asn Trp Lys Lys Gln Phe Gly 
                85                  90                  95      


Ala Glu Cys Lys Tyr Gln Phe Gln Ala Trp Gly Glu Cys Asp Leu Asn 
            100                 105                 110         


Thr Ala Leu Lys Thr Arg Thr Gly Ser Leu Lys Arg Ala Leu His Asn 
        115                 120                 125             


Ala Glu Cys Gln Lys Thr Val Thr Ile Ser Lys Pro Cys Gly Lys Leu 
    130                 135                 140                 


Thr Lys Pro Lys Pro Gln Ala Glu Ser Lys Lys Lys Lys Lys Glu Gly 
145                 150                 155                 160 


Lys Lys Gln Glu Lys Met Leu Asp 
                165             


<210>  1382
<211>  479
<212>  PRT
<213>  Human

<400>  1382

Met Ala Arg Ala Ala Ala Leu Leu Pro Ser Arg Ser Pro Pro Thr Pro 
1               5                   10                  15      


Leu Leu Trp Pro Leu Leu Leu Leu Leu Leu Leu Glu Thr Gly Ala Gln 
            20                  25                  30          


Asp Val Arg Val Gln Val Leu Pro Glu Val Arg Gly Gln Leu Gly Gly 
        35                  40                  45              


Thr Val Glu Leu Pro Cys His Leu Leu Pro Pro Val Pro Gly Leu Tyr 
    50                  55                  60                  


Ile Ser Leu Val Thr Trp Gln Arg Pro Asp Ala Pro Ala Asn His Gln 
65                  70                  75                  80  


Asn Val Ala Ala Phe His Pro Lys Met Gly Pro Ser Phe Pro Ser Pro 
                85                  90                  95      


Lys Pro Gly Ser Glu Arg Leu Ser Phe Val Ser Ala Lys Gln Ser Thr 
            100                 105                 110         


Gly Gln Asp Thr Glu Ala Glu Leu Gln Asp Ala Thr Leu Ala Leu His 
        115                 120                 125             


Gly Leu Thr Val Glu Asp Glu Gly Asn Tyr Thr Cys Glu Phe Ala Thr 
    130                 135                 140                 


Phe Pro Lys Gly Ser Val Arg Gly Met Thr Trp Leu Arg Val Ile Ala 
145                 150                 155                 160 


Lys Pro Lys Asn Gln Ala Glu Ala Gln Lys Val Thr Phe Ser Gln Asp 
                165                 170                 175     


Pro Thr Thr Val Ala Leu Cys Ile Ser Lys Glu Gly Arg Pro Pro Ala 
            180                 185                 190         


Arg Ile Ser Trp Leu Ser Ser Leu Asp Trp Glu Ala Lys Glu Thr Gln 
        195                 200                 205             


Val Ser Gly Thr Leu Ala Gly Thr Val Thr Val Thr Ser Arg Phe Thr 
    210                 215                 220                 


Leu Val Pro Ser Gly Arg Ala Asp Gly Val Thr Val Thr Cys Lys Val 
225                 230                 235                 240 


Glu His Glu Ser Phe Glu Glu Pro Ala Leu Ile Pro Val Thr Leu Ser 
                245                 250                 255     


Val Arg Tyr Pro Pro Glu Val Ser Ile Ser Gly Tyr Asp Asp Asn Trp 
            260                 265                 270         


Tyr Leu Gly Arg Thr Asp Ala Thr Leu Ser Cys Asp Val Arg Ser Asn 
        275                 280                 285             


Pro Glu Pro Thr Gly Tyr Asp Trp Ser Thr Thr Ser Gly Thr Phe Pro 
    290                 295                 300                 


Thr Ser Ala Val Ala Gln Gly Ser Gln Leu Val Ile His Ala Val Asp 
305                 310                 315                 320 


Ser Leu Phe Asn Thr Thr Phe Val Cys Thr Val Thr Asn Ala Val Gly 
                325                 330                 335     


Met Gly Arg Ala Glu Gln Val Ile Phe Val Arg Glu Thr Pro Arg Ala 
            340                 345                 350         


Ser Pro Arg Asp Val Gly Pro Leu Val Trp Gly Ala Val Gly Gly Thr 
        355                 360                 365             


Leu Leu Val Leu Leu Leu Leu Ala Gly Gly Ser Leu Ala Phe Ile Leu 
    370                 375                 380                 


Leu Arg Val Arg Arg Arg Arg Lys Ser Pro Gly Gly Ala Gly Gly Gly 
385                 390                 395                 400 


Ala Ser Gly Asp Gly Gly Phe Tyr Asp Pro Lys Ala Gln Val Leu Gly 
                405                 410                 415     


Asn Gly Asp Pro Val Phe Trp Thr Pro Val Val Pro Gly Pro Met Glu 
            420                 425                 430         


Pro Asp Gly Lys Asp Glu Glu Glu Glu Glu Glu Glu Glu Lys Ala Glu 
        435                 440                 445             


Lys Gly Leu Met Leu Pro Pro Pro Pro Ala Leu Glu Asp Asp Met Glu 
    450                 455                 460                 


Ser Gln Leu Asp Gly Ser Leu Ile Ser Arg Arg Ala Val Tyr Val 
465                 470                 475                 


<210>  1383
<211>  319
<212>  PRT
<213>  Human

<400>  1383

Met Ser Val Gly Phe Ile Gly Ala Gly Gln Leu Ala Phe Ala Leu Ala 
1               5                   10                  15      


Lys Gly Phe Thr Ala Ala Gly Val Leu Ala Ala His Lys Ile Met Ala 
            20                  25                  30          


Ser Ser Pro Asp Met Asp Leu Ala Thr Val Ser Ala Leu Arg Lys Met 
        35                  40                  45              


Gly Val Lys Leu Thr Pro His Asn Lys Glu Thr Val Gln His Ser Asp 
    50                  55                  60                  


Val Leu Phe Leu Ala Val Lys Pro His Ile Ile Pro Phe Ile Leu Asp 
65                  70                  75                  80  


Glu Ile Gly Ala Asp Ile Glu Asp Arg His Ile Val Val Ser Cys Ala 
                85                  90                  95      


Ala Gly Val Thr Ile Ser Ser Ile Glu Lys Lys Leu Ser Ala Phe Arg 
            100                 105                 110         


Pro Ala Pro Arg Val Ile Arg Cys Met Thr Asn Thr Pro Val Val Val 
        115                 120                 125             


Arg Glu Gly Ala Thr Val Tyr Ala Thr Gly Thr His Ala Gln Val Glu 
    130                 135                 140                 


Asp Gly Arg Leu Met Glu Gln Leu Leu Ser Ser Val Gly Phe Cys Thr 
145                 150                 155                 160 


Glu Val Glu Glu Asp Leu Ile Asp Ala Val Thr Gly Leu Ser Gly Ser 
                165                 170                 175     


Gly Pro Ala Tyr Ala Phe Thr Ala Leu Asp Ala Leu Ala Asp Gly Gly 
            180                 185                 190         


Val Lys Met Gly Leu Pro Arg Arg Leu Ala Val Arg Leu Gly Ala Gln 
        195                 200                 205             


Ala Leu Leu Gly Ala Ala Lys Met Leu Leu His Ser Glu Gln His Pro 
    210                 215                 220                 


Gly Gln Leu Lys Asp Asn Val Ser Ser Pro Gly Gly Ala Thr Ile His 
225                 230                 235                 240 


Ala Leu His Val Leu Glu Ser Gly Gly Phe Arg Ser Leu Leu Ile Asn 
                245                 250                 255     


Ala Val Glu Ala Ser Cys Ile Arg Thr Arg Glu Leu Gln Ser Met Ala 
            260                 265                 270         


Asp Gln Glu Gln Val Ser Pro Ala Ala Ile Lys Lys Thr Ile Leu Asp 
        275                 280                 285             


Lys Val Lys Leu Asp Ser Pro Ala Gly Thr Ala Leu Ser Pro Ser Gly 
    290                 295                 300                 


His Thr Lys Leu Leu Pro Arg Ser Leu Ala Pro Ala Gly Lys Asp 
305                 310                 315                 


<210>  1384
<211>  248
<212>  PRT
<213>  Human

<400>  1384

Met Arg Leu Ile Gln Asn Met Cys Thr Ile Ala Glu Tyr Pro Ala Pro 
1               5                   10                  15      


Gly Asn Ala Ala Ala Ser Asp Cys Cys Val Gly Ala Ala Gly Arg Arg 
            20                  25                  30          


Leu Val Lys Ile Ala Val Val Gly Ala Ser Gly Val Gly Lys Thr Ala 
        35                  40                  45              


Leu Val Val Arg Phe Leu Thr Lys Arg Phe Ile Gly Asp Tyr Glu Arg 
    50                  55                  60                  


Asn Ala Gly Asn Leu Tyr Thr Arg Gln Val Gln Ile Glu Gly Glu Thr 
65                  70                  75                  80  


Leu Ala Leu Gln Val Gln Asp Thr Pro Gly Ile Gln Val His Glu Asn 
                85                  90                  95      


Ser Leu Ser Cys Ser Glu Gln Leu Asn Arg Cys Ile Arg Trp Ala Asp 
            100                 105                 110         


Ala Val Val Ile Val Phe Ser Ile Thr Asp Tyr Lys Ser Tyr Glu Leu 
        115                 120                 125             


Ile Ser Gln Leu His Gln His Val Gln Gln Leu His Leu Gly Thr Arg 
    130                 135                 140                 


Leu Pro Val Val Val Val Ala Asn Lys Ala Asp Leu Leu His Ile Lys 
145                 150                 155                 160 


Gln Val Asp Pro Gln Leu Gly Leu Gln Leu Ala Ser Met Leu Gly Cys 
                165                 170                 175     


Ser Phe Tyr Glu Val Ser Val Ser Glu Asn Tyr Asn Asp Val Tyr Ser 
            180                 185                 190         


Ala Phe His Val Leu Cys Lys Glu Val Ser His Lys Gln Gln Pro Ser 
        195                 200                 205             


Ser Thr Pro Glu Lys Arg Arg Thr Ser Leu Ile Pro Arg Pro Lys Ser 
    210                 215                 220                 


Pro Asn Met Gln Asp Leu Lys Arg Arg Phe Lys Gln Ala Leu Ser Ala 
225                 230                 235                 240 


Lys Val Arg Thr Val Thr Ser Val 
                245             


<210>  1385
<211>  311
<212>  PRT
<213>  Human

<400>  1385

Met Ala Glu Ala Ser Pro His Pro Gly Arg Tyr Phe Cys His Cys Cys 
1               5                   10                  15      


Ser Val Glu Ile Val Pro Arg Leu Pro Asp Tyr Ile Cys Pro Arg Cys 
            20                  25                  30          


Glu Ser Gly Phe Ile Glu Glu Leu Pro Glu Glu Thr Arg Ser Thr Glu 
        35                  40                  45              


Asn Gly Ser Ala Pro Ser Thr Ala Pro Thr Asp Gln Ser Arg Pro Pro 
    50                  55                  60                  


Leu Glu His Val Asp Gln His Leu Phe Thr Leu Pro Gln Gly Tyr Gly 
65                  70                  75                  80  


Gln Phe Ala Phe Gly Ile Phe Asp Asp Ser Phe Glu Ile Pro Thr Phe 
                85                  90                  95      


Pro Pro Gly Ala Gln Ala Asp Asp Gly Arg Asp Pro Glu Ser Arg Arg 
            100                 105                 110         


Glu Arg Asp His Pro Ser Arg His Arg Tyr Gly Ala Arg Gln Pro Arg 
        115                 120                 125             


Ala Arg Leu Thr Thr Arg Arg Ala Thr Gly Arg His Glu Gly Val Pro 
    130                 135                 140                 


Thr Leu Glu Gly Ile Ile Gln Gln Leu Val Asn Gly Ile Ile Thr Pro 
145                 150                 155                 160 


Ala Thr Ile Pro Ser Leu Gly Pro Trp Gly Val Leu His Ser Asn Pro 
                165                 170                 175     


Met Asp Tyr Ala Trp Gly Ala Asn Gly Leu Asp Ala Ile Ile Thr Gln 
            180                 185                 190         


Leu Leu Asn Gln Phe Glu Asn Thr Gly Pro Pro Pro Ala Asp Lys Glu 
        195                 200                 205             


Lys Ile Gln Ala Leu Pro Thr Val Pro Val Thr Glu Glu His Val Gly 
    210                 215                 220                 


Ser Gly Leu Glu Cys Pro Val Cys Lys Asp Asp Tyr Ala Leu Gly Glu 
225                 230                 235                 240 


Arg Val Arg Gln Leu Pro Cys Asn His Leu Phe His Asp Gly Cys Ile 
                245                 250                 255     


Val Pro Trp Leu Glu Gln His Asp Ser Cys Pro Val Cys Arg Lys Ser 
            260                 265                 270         


Leu Thr Gly Gln Asn Thr Ala Thr Asn Pro Pro Gly Leu Thr Gly Val 
        275                 280                 285             


Ser Phe Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Pro Ser Asn 
    290                 295                 300                 


Glu Asn Ala Thr Ser Asn Ser 
305                 310     


<210>  1386
<211>  237
<212>  PRT
<213>  Human

<400>  1386

Met Ala Met Phe Arg Ser Leu Val Ala Ser Ala Gln Gln Arg Gln Pro 
1               5                   10                  15      


Pro Ala Gly Pro Ala Gly Gly Asp Ser Gly Leu Glu Ala Gln Tyr Thr 
            20                  25                  30          


Cys Pro Ile Cys Leu Glu Val Tyr His Arg Pro Val Ala Ile Gly Ser 
        35                  40                  45              


Cys Gly His Thr Phe Cys Gly Glu Cys Leu Gln Pro Cys Leu Gln Val 
    50                  55                  60                  


Pro Ser Pro Leu Cys Pro Leu Cys Arg Leu Pro Phe Asp Pro Lys Lys 
65                  70                  75                  80  


Val Asp Lys Ala Thr His Val Glu Lys Gln Leu Ser Ser Tyr Lys Ala 
                85                  90                  95      


Pro Cys Arg Gly Cys Asn Lys Lys Val Thr Leu Ala Lys Met Arg Val 
            100                 105                 110         


His Ile Ser Ser Cys Leu Lys Val Gln Glu Gln Met Ala Asn Cys Pro 
        115                 120                 125             


Lys Phe Val Pro Val Val Pro Thr Ser Gln Pro Ile Pro Ser Asn Ile 
    130                 135                 140                 


Pro Asn Arg Ser Thr Phe Ala Cys Pro Tyr Cys Gly Ala Arg Asn Leu 
145                 150                 155                 160 


Asp Gln Gln Glu Leu Val Lys His Cys Val Glu Ser His Arg Ser Asp 
                165                 170                 175     


Pro Asn Arg Val Val Cys Pro Ile Cys Ser Ala Met Pro Trp Gly Asp 
            180                 185                 190         


Pro Ser Tyr Lys Ser Ala Asn Phe Leu Gln His Leu Leu His Arg His 
        195                 200                 205             


Lys Phe Ser Tyr Asp Thr Phe Val Asp Tyr Ser Ile Asp Glu Glu Ala 
    210                 215                 220                 


Ala Phe Gln Ala Ala Leu Ala Leu Ser Leu Ser Glu Asn 
225                 230                 235         


<210>  1387
<211>  485
<212>  PRT
<213>  Human

<400>  1387

Met Gly Glu Pro Gly Phe Phe Val Thr Gly Asp Arg Ala Gly Gly Arg 
1               5                   10                  15      


Ser Trp Cys Leu Arg Arg Val Gly Met Ser Ala Gly Trp Leu Leu Leu 
            20                  25                  30          


Glu Asp Gly Cys Glu Val Thr Val Gly Arg Gly Phe Gly Val Thr Tyr 
        35                  40                  45              


Gln Leu Val Ser Lys Ile Cys Pro Leu Met Ile Ser Arg Asn His Cys 
    50                  55                  60                  


Val Leu Lys Gln Asn Pro Glu Gly Gln Trp Thr Ile Met Asp Asn Lys 
65                  70                  75                  80  


Ser Leu Asn Gly Val Trp Leu Asn Arg Ala Arg Leu Glu Pro Leu Arg 
                85                  90                  95      


Val Tyr Ser Ile His Gln Gly Asp Tyr Ile Gln Leu Gly Val Pro Leu 
            100                 105                 110         


Glu Asn Lys Glu Asn Ala Glu Tyr Glu Tyr Glu Val Thr Glu Glu Asp 
        115                 120                 125             


Trp Glu Thr Ile Tyr Pro Cys Leu Ser Pro Lys Asn Asp Gln Met Ile 
    130                 135                 140                 


Glu Lys Asn Lys Glu Leu Arg Thr Lys Arg Lys Phe Ser Leu Asp Glu 
145                 150                 155                 160 


Leu Ala Gly Pro Gly Ala Glu Gly Pro Ser Asn Leu Lys Ser Lys Ile 
                165                 170                 175     


Asn Lys Val Ser Cys Glu Ser Gly Gln Pro Val Lys Ser Gln Gly Lys 
            180                 185                 190         


Gly Glu Val Ala Ser Thr Pro Ser Asp Asn Leu Asp Pro Lys Leu Thr 
        195                 200                 205             


Ala Leu Glu Pro Ser Lys Thr Thr Gly Ala Pro Ile Tyr Pro Gly Phe 
    210                 215                 220                 


Pro Lys Val Thr Glu Val His His Glu Gln Lys Ala Ser Asn Ser Ser 
225                 230                 235                 240 


Ala Ser Gln Arg Ser Leu Gln Met Phe Lys Val Thr Met Ser Arg Ile 
                245                 250                 255     


Leu Arg Leu Lys Ile Gln Met Gln Glu Lys His Glu Ala Val Met Asn 
            260                 265                 270         


Val Lys Lys Gln Thr Gln Lys Gly Asn Ser Lys Lys Val Val Gln Met 
        275                 280                 285             


Glu Gln Glu Leu Gln Asp Leu Gln Ser Gln Leu Cys Ala Glu Gln Ala 
    290                 295                 300                 


Gln Gln Gln Ala Arg Val Glu Gln Leu Glu Lys Thr Phe Gln Glu Glu 
305                 310                 315                 320 


Glu Gln His Leu Gln Gly Leu Glu Ile Ala Gln Gly Glu Lys Asp Leu 
                325                 330                 335     


Lys Gln Gln Leu Ala Gln Ala Leu Gln Glu His Trp Ala Leu Met Glu 
            340                 345                 350         


Glu Leu Asn Arg Ser Lys Lys Asp Phe Glu Ala Ile Ile Gln Ala Lys 
        355                 360                 365             


Asn Lys Glu Leu Glu Gln Thr Lys Glu Glu Lys Glu Lys Met Gln Ala 
    370                 375                 380                 


Gln Lys Glu Glu Val Leu Ser His Met Asn Asp Val Leu Glu Asn Glu 
385                 390                 395                 400 


Leu Gln Cys Ile Ile Cys Ser Glu Tyr Phe Ile Glu Ala Val Thr Leu 
                405                 410                 415     


Asn Cys Ala His Ser Phe Cys Ser Tyr Cys Ile Asn Glu Trp Met Lys 
            420                 425                 430         


Arg Lys Ile Glu Cys Pro Ile Cys Arg Lys Asp Ile Lys Ser Lys Thr 
        435                 440                 445             


Tyr Ser Leu Val Leu Asp Asn Cys Ile Asn Lys Met Val Asn Asn Leu 
    450                 455                 460                 


Ser Ser Glu Val Lys Glu Arg Arg Ile Val Leu Ile Arg Glu Arg Lys 
465                 470                 475                 480 


Ala Lys Arg Leu Phe 
                485 


<210>  1388
<211>  1378
<212>  PRT
<213>  Human

<400>  1388

Met Ser Leu Leu Met Phe Thr Gln Leu Leu Leu Cys Gly Phe Leu Tyr 
1               5                   10                  15      


Val Arg Val Asp Gly Ser Arg Leu Arg Gln Glu Asp Phe Pro Pro Arg 
            20                  25                  30          


Ile Val Glu His Pro Ser Asp Val Ile Val Ser Lys Gly Glu Pro Thr 
        35                  40                  45              


Thr Leu Asn Cys Lys Ala Glu Gly Arg Pro Thr Pro Thr Ile Glu Trp 
    50                  55                  60                  


Tyr Lys Asp Gly Glu Arg Val Glu Thr Asp Lys Asp Asp Pro Arg Ser 
65                  70                  75                  80  


His Arg Met Leu Leu Pro Ser Gly Ser Leu Phe Phe Leu Arg Ile Val 
                85                  90                  95      


His Gly Arg Arg Ser Lys Pro Asp Glu Gly Ser Tyr Val Cys Val Ala 
            100                 105                 110         


Arg Asn Tyr Leu Gly Glu Ala Val Ser Arg Asn Ala Ser Leu Glu Val 
        115                 120                 125             


Ala Leu Leu Arg Asp Asp Phe Arg Gln Asn Pro Thr Asp Val Val Val 
    130                 135                 140                 


Ala Ala Gly Glu Pro Ala Ile Leu Glu Cys Gln Pro Pro Arg Gly His 
145                 150                 155                 160 


Pro Glu Pro Thr Ile Tyr Trp Lys Lys Asp Lys Val Arg Ile Asp Asp 
                165                 170                 175     


Lys Glu Glu Arg Ile Ser Ile Arg Gly Gly Lys Leu Met Ile Ser Asn 
            180                 185                 190         


Thr Arg Lys Ser Asp Ala Gly Met Tyr Thr Cys Val Gly Thr Asn Met 
        195                 200                 205             


Val Gly Glu Arg Asp Ser Asp Pro Ala Glu Leu Thr Val Phe Glu Arg 
    210                 215                 220                 


Pro Thr Phe Leu Arg Arg Pro Ile Asn Gln Val Val Leu Glu Glu Glu 
225                 230                 235                 240 


Ala Val Glu Phe Arg Cys Gln Val Gln Gly Asp Pro Gln Pro Thr Val 
                245                 250                 255     


Arg Trp Lys Lys Asp Asp Ala Asp Leu Pro Arg Gly Arg Tyr Asp Ile 
            260                 265                 270         


Lys Asp Asp Tyr Thr Leu Arg Ile Lys Lys Thr Met Ser Thr Asp Glu 
        275                 280                 285             


Gly Thr Tyr Met Cys Ile Ala Glu Asn Arg Val Gly Lys Met Glu Ala 
    290                 295                 300                 


Ser Ala Thr Leu Thr Val Arg Ala Pro Pro Gln Phe Val Val Arg Pro 
305                 310                 315                 320 


Arg Asp Gln Ile Val Ala Gln Gly Arg Thr Val Thr Phe Pro Cys Glu 
                325                 330                 335     


Thr Lys Gly Asn Pro Gln Pro Ala Val Phe Trp Gln Lys Glu Gly Ser 
            340                 345                 350         


Gln Asn Leu Leu Phe Pro Asn Gln Pro Gln Gln Pro Asn Ser Arg Cys 
        355                 360                 365             


Ser Val Ser Pro Thr Gly Asp Leu Thr Ile Thr Asn Ile Gln Arg Ser 
    370                 375                 380                 


Asp Ala Gly Tyr Tyr Ile Cys Gln Ala Leu Thr Val Ala Gly Ser Ile 
385                 390                 395                 400 


Leu Ala Lys Ala Gln Leu Glu Val Thr Asp Val Leu Thr Asp Arg Pro 
                405                 410                 415     


Pro Pro Ile Ile Leu Gln Gly Pro Ala Asn Gln Thr Leu Ala Val Asp 
            420                 425                 430         


Gly Thr Ala Leu Leu Lys Cys Lys Ala Thr Gly Asp Pro Leu Pro Val 
        435                 440                 445             


Ile Ser Trp Leu Lys Glu Gly Phe Thr Phe Pro Gly Arg Asp Pro Arg 
    450                 455                 460                 


Ala Thr Ile Gln Glu Gln Gly Thr Leu Gln Ile Lys Asn Leu Arg Ile 
465                 470                 475                 480 


Ser Asp Thr Gly Thr Tyr Thr Cys Val Ala Thr Ser Ser Ser Gly Glu 
                485                 490                 495     


Thr Ser Trp Ser Ala Val Leu Asp Val Thr Glu Ser Gly Ala Thr Ile 
            500                 505                 510         


Ser Lys Asn Tyr Asp Leu Ser Asp Leu Pro Gly Pro Pro Ser Lys Pro 
        515                 520                 525             


Gln Val Thr Asp Val Thr Lys Asn Ser Val Thr Leu Ser Trp Gln Pro 
    530                 535                 540                 


Gly Thr Pro Gly Thr Leu Pro Ala Ser Ala Tyr Ile Ile Glu Ala Phe 
545                 550                 555                 560 


Ser Gln Ser Val Ser Asn Ser Trp Gln Thr Val Ala Asn His Val Lys 
                565                 570                 575     


Thr Thr Leu Tyr Thr Val Arg Gly Leu Arg Pro Asn Thr Ile Tyr Leu 
            580                 585                 590         


Phe Met Val Arg Ala Ile Asn Pro Gln Gly Leu Ser Asp Pro Ser Pro 
        595                 600                 605             


Met Ser Asp Pro Val Arg Thr Gln Asp Ile Ser Pro Pro Ala Gln Gly 
    610                 615                 620                 


Val Asp His Arg Gln Val Gln Lys Glu Leu Gly Asp Val Leu Val Arg 
625                 630                 635                 640 


Leu His Asn Pro Val Val Leu Thr Pro Thr Thr Val Gln Val Thr Trp 
                645                 650                 655     


Thr Val Asp Arg Gln Pro Gln Phe Ile Gln Gly Tyr Arg Val Met Tyr 
            660                 665                 670         


Arg Gln Thr Ser Gly Leu Gln Ala Thr Ser Ser Trp Gln Asn Leu Asp 
        675                 680                 685             


Ala Lys Val Pro Thr Glu Arg Ser Ala Val Leu Val Asn Leu Lys Lys 
    690                 695                 700                 


Gly Val Thr Tyr Glu Ile Lys Val Arg Pro Tyr Phe Asn Glu Phe Gln 
705                 710                 715                 720 


Gly Met Asp Ser Glu Ser Lys Thr Val Arg Thr Thr Glu Glu Ala Pro 
                725                 730                 735     


Ser Ala Pro Pro Gln Ser Val Thr Val Leu Thr Val Gly Ser Tyr Asn 
            740                 745                 750         


Ser Thr Ser Ile Ser Val Ser Trp Asp Pro Pro Pro Pro Asp His Gln 
        755                 760                 765             


Asn Gly Ile Ile Gln Glu Tyr Lys Ile Trp Cys Leu Gly Asn Glu Thr 
    770                 775                 780                 


Arg Phe His Ile Asn Lys Thr Val Asp Ala Ala Ile Arg Ser Val Ile 
785                 790                 795                 800 


Ile Gly Gly Leu Phe Pro Gly Ile Gln Tyr Arg Val Glu Val Ala Ala 
                805                 810                 815     


Ser Thr Ser Ala Gly Val Gly Val Lys Ser Glu Pro Gln Pro Ile Ile 
            820                 825                 830         


Ile Gly Arg Arg Asn Glu Val Val Ile Thr Glu Asn Asn Asn Ser Ile 
        835                 840                 845             


Thr Glu Gln Ile Thr Asp Val Val Lys Gln Pro Ala Phe Ile Ala Gly 
    850                 855                 860                 


Ile Gly Gly Ala Cys Trp Val Ile Leu Met Gly Phe Ser Ile Trp Leu 
865                 870                 875                 880 


Tyr Trp Arg Arg Lys Lys Arg Lys Gly Leu Ser Asn Tyr Ala Val Thr 
                885                 890                 895     


Phe Gln Arg Gly Asp Gly Gly Leu Met Ser Asn Gly Ser Arg Pro Gly 
            900                 905                 910         


Leu Leu Asn Ala Gly Asp Pro Ser Tyr Pro Trp Leu Ala Asp Ser Trp 
        915                 920                 925             


Pro Ala Thr Ser Leu Pro Val Asn Asn Ser Asn Ser Gly Pro Asn Glu 
    930                 935                 940                 


Ile Gly Asn Phe Gly Arg Gly Asp Val Leu Pro Pro Val Pro Gly Gln 
945                 950                 955                 960 


Gly Asp Lys Thr Ala Thr Met Leu Ser Asp Gly Ala Ile Tyr Ser Ser 
                965                 970                 975     


Ile Asp Phe Thr Thr Lys Thr Ser Tyr Asn Ser Ser Ser Gln Ile Thr 
            980                 985                 990         


Gln Ala Thr Pro Tyr Ala Thr Thr  Gln Ile Leu His Ser  Asn Ser Ile 
        995                 1000                 1005             


His Glu  Leu Ala Val Asp Leu  Pro Asp Pro Gln Trp  Lys Ser Ser 
    1010                 1015                 1020             


Ile Gln  Gln Lys Thr Asp Leu  Met Gly Phe Gly Tyr  Ser Leu Pro 
    1025                 1030                 1035             


Asp Gln  Asn Lys Gly Asn Asn  Gly Gly Lys Gly Gly  Lys Lys Lys 
    1040                 1045                 1050             


Lys Asn  Lys Asn Ser Ser Lys  Pro Gln Lys Asn Asn  Gly Ser Thr 
    1055                 1060                 1065             


Trp Ala  Asn Val Pro Leu Pro  Pro Pro Pro Val Gln  Pro Leu Pro 
    1070                 1075                 1080             


Gly Thr  Glu Leu Glu His Tyr  Ala Val Glu Gln Gln  Glu Asn Gly 
    1085                 1090                 1095             


Tyr Asp  Ser Asp Ser Trp Cys  Pro Pro Leu Pro Val  Gln Thr Tyr 
    1100                 1105                 1110             


Leu His  Gln Gly Leu Glu Asp  Glu Leu Glu Glu Asp  Asp Asp Arg 
    1115                 1120                 1125             


Val Pro  Thr Pro Pro Val Arg  Gly Val Ala Ser Ser  Pro Ala Ile 
    1130                 1135                 1140             


Ser Phe  Gly Gln Gln Ser Thr  Ala Thr Leu Thr Pro  Ser Pro Arg 
    1145                 1150                 1155             


Glu Glu  Met Gln Pro Met Leu  Gln Ala His Leu Asp  Glu Leu Thr 
    1160                 1165                 1170             


Arg Ala  Tyr Gln Phe Asp Ile  Ala Lys Gln Thr Trp  His Ile Gln 
    1175                 1180                 1185             


Ser Asn  Asn Gln Pro Pro Gln  Pro Pro Val Pro Pro  Leu Gly Tyr 
    1190                 1195                 1200             


Val Ser  Gly Ala Leu Ile Ser  Asp Leu Glu Thr Asp  Val Ala Asp 
    1205                 1210                 1215             


Asp Asp  Ala Asp Asp Glu Glu  Glu Ala Leu Glu Ile  Pro Arg Pro 
    1220                 1225                 1230             


Leu Arg  Ala Leu Asp Gln Thr  Pro Gly Ser Ser Met  Asp Asn Leu 
    1235                 1240                 1245             


Asp Ser  Ser Val Thr Gly Lys  Ala Phe Thr Ser Ser  Gln Arg Pro 
    1250                 1255                 1260             


Arg Pro  Thr Ser Pro Phe Ser  Thr Asp Ser Asn Thr  Ser Ala Ala 
    1265                 1270                 1275             


Leu Ser  Gln Ser Gln Arg Pro  Arg Pro Thr Lys Lys  His Lys Gly 
    1280                 1285                 1290             


Gly Arg  Met Asp Gln Gln Pro  Ala Leu Pro His Arg  Arg Glu Gly 
    1295                 1300                 1305             


Met Thr  Asp Glu Glu Ala Leu  Val Pro Tyr Ser Lys  Pro Ser Phe 
    1310                 1315                 1320             


Pro Ser  Pro Gly Gly His Ser  Ser Ser Gly Thr Ala  Ser Ser Lys 
    1325                 1330                 1335             


Gly Ser  Thr Gly Pro Arg Lys  Thr Glu Val Leu Arg  Ala Gly His 
    1340                 1345                 1350             


Gln Arg  Asn Ala Ser Asp Leu  Leu Asp Ile Gly Tyr  Met Gly Ser 
    1355                 1360                 1365             


Asn Ser  Gln Gly Gln Phe Thr  Gly Glu Leu 
    1370                 1375             


<210>  1389
<211>  1386
<212>  PRT
<213>  Human

<400>  1389

Met Leu Arg Tyr Leu Leu Lys Thr Leu Leu Gln Met Asn Leu Phe Ala 
1               5                   10                  15      


Asp Ser Leu Ala Gly Asp Ile Ser Asn Ser Ser Glu Leu Leu Leu Gly 
            20                  25                  30          


Phe Asn Ser Ser Leu Ala Ala Leu Asn His Thr Leu Leu Pro Pro Gly 
        35                  40                  45              


Asp Pro Ser Leu Asn Gly Ser Arg Val Gly Pro Glu Asp Ala Met Pro 
    50                  55                  60                  


Arg Ile Val Glu Gln Pro Pro Asp Leu Leu Val Ser Arg Gly Glu Pro 
65                  70                  75                  80  


Ala Thr Leu Pro Cys Arg Ala Glu Gly Arg Pro Arg Pro Asn Ile Glu 
                85                  90                  95      


Trp Tyr Lys Asn Gly Ala Arg Val Ala Thr Val Arg Glu Asp Pro Arg 
            100                 105                 110         


Ala His Arg Leu Leu Leu Pro Ser Gly Ala Leu Phe Phe Pro Arg Ile 
        115                 120                 125             


Val His Gly Arg Arg Ala Arg Pro Asp Glu Gly Val Tyr Thr Cys Val 
    130                 135                 140                 


Ala Arg Asn Tyr Leu Gly Ala Ala Ala Ser Arg Asn Ala Ser Leu Glu 
145                 150                 155                 160 


Val Ala Val Leu Arg Asp Asp Phe Arg Gln Ser Pro Gly Asn Val Val 
                165                 170                 175     


Val Ala Val Gly Glu Pro Ala Val Leu Glu Cys Val Pro Pro Arg Gly 
            180                 185                 190         


His Pro Glu Pro Ser Val Ser Trp Arg Lys Asp Gly Ala Arg Leu Lys 
        195                 200                 205             


Glu Glu Glu Gly Arg Ile Thr Ile Arg Gly Gly Lys Leu Met Met Ser 
    210                 215                 220                 


His Thr Leu Lys Ser Asp Ala Gly Met Tyr Val Cys Val Ala Ser Asn 
225                 230                 235                 240 


Met Ala Gly Glu Arg Glu Ser Ala Ala Ala Glu Val Met Val Leu Glu 
                245                 250                 255     


Arg Pro Ser Phe Leu Arg Arg Pro Val Asn Gln Val Val Leu Ala Asp 
            260                 265                 270         


Ala Pro Val Thr Phe Leu Cys Glu Val Lys Gly Asp Pro Pro Pro Arg 
        275                 280                 285             


Leu Arg Trp Arg Lys Glu Asp Gly Glu Leu Pro Thr Gly Arg Tyr Glu 
    290                 295                 300                 


Ile Arg Ser Asp His Ser Leu Trp Ile Gly His Val Ser Ala Glu Asp 
305                 310                 315                 320 


Glu Gly Thr Tyr Thr Cys Val Ala Glu Asn Ser Val Gly Arg Ala Glu 
                325                 330                 335     


Ala Ser Gly Ser Leu Ser Val His Val Pro Pro Gln Leu Val Thr Gln 
            340                 345                 350         


Pro Gln Asp Gln Met Ala Ala Pro Gly Glu Ser Val Ala Phe Gln Cys 
        355                 360                 365             


Glu Thr Lys Gly Asn Pro Pro Pro Ala Ile Phe Trp Gln Lys Glu Gly 
    370                 375                 380                 


Ser Gln Val Leu Leu Phe Pro Ser Gln Ser Leu Gln Pro Thr Gly Arg 
385                 390                 395                 400 


Phe Ser Val Ser Pro Arg Gly Gln Leu Asn Ile Thr Ala Val Gln Arg 
                405                 410                 415     


Gly Asp Ala Gly Tyr Tyr Val Cys Gln Ala Val Ser Val Ala Gly Ser 
            420                 425                 430         


Ile Leu Ala Lys Ala Leu Leu Glu Ile Lys Gly Ala Ser Leu Asp Gly 
        435                 440                 445             


Leu Pro Pro Val Ile Leu Gln Gly Pro Ala Asn Gln Thr Leu Val Leu 
    450                 455                 460                 


Gly Ser Ser Val Trp Leu Pro Cys Arg Val Thr Gly Asn Pro Gln Pro 
465                 470                 475                 480 


Ser Val Arg Trp Lys Lys Asp Gly Gln Trp Leu Gln Gly Asp Asp Leu 
                485                 490                 495     


Gln Phe Lys Thr Met Ala Asn Gly Thr Leu Tyr Ile Ala Asn Val Gln 
            500                 505                 510         


Glu Met Asp Met Gly Phe Tyr Ser Cys Val Ala Lys Ser Ser Thr Gly 
        515                 520                 525             


Glu Ala Thr Trp Ser Gly Trp Leu Lys Met Arg Glu Asp Trp Gly Val 
    530                 535                 540                 


Ser Pro Asp Pro Pro Thr Glu Pro Ser Ser Pro Pro Gly Ala Pro Ser 
545                 550                 555                 560 


Gln Pro Val Val Thr Glu Ile Thr Lys Asn Ser Ile Thr Leu Thr Trp 
                565                 570                 575     


Lys Pro Asn Pro Gln Thr Gly Ala Ala Val Thr Ser Tyr Val Ile Glu 
            580                 585                 590         


Ala Phe Ser Pro Ala Ala Gly Asn Thr Trp Arg Thr Val Ala Asp Gly 
        595                 600                 605             


Val Gln Leu Glu Thr His Thr Val Ser Gly Leu Gln Pro Asn Thr Ile 
    610                 615                 620                 


Tyr Leu Phe Leu Val Arg Ala Val Gly Ala Trp Gly Leu Ser Glu Pro 
625                 630                 635                 640 


Ser Pro Val Ser Glu Pro Val Arg Thr Gln Asp Ser Ser Pro Ser Arg 
                645                 650                 655     


Pro Val Glu Asp Pro Trp Arg Gly Gln Gln Gly Leu Ala Glu Val Ala 
            660                 665                 670         


Val Arg Leu Gln Glu Pro Ile Val Leu Gly Pro Arg Thr Leu Gln Val 
        675                 680                 685             


Ser Trp Thr Val Asp Gly Pro Val Gln Leu Val Gln Gly Phe Arg Val 
    690                 695                 700                 


Ser Trp Arg Val Ala Gly Pro Glu Gly Gly Ser Trp Thr Met Leu Asp 
705                 710                 715                 720 


Leu Gln Ser Pro Ser Gln Gln Ser Thr Val Leu Arg Gly Leu Pro Pro 
                725                 730                 735     


Gly Thr Gln Ile Gln Ile Lys Val Gln Ala Gln Gly Gln Glu Gly Leu 
            740                 745                 750         


Gly Ala Glu Ser Leu Ser Val Thr Arg Ser Ile Pro Glu Glu Ala Pro 
        755                 760                 765             


Ser Gly Pro Pro Gln Gly Val Ala Val Ala Leu Gly Gly Asp Gly Asn 
    770                 775                 780                 


Ser Ser Ile Thr Val Ser Trp Glu Pro Pro Leu Pro Ser Gln Gln Asn 
785                 790                 795                 800 


Gly Val Ile Thr Glu Tyr Gln Ile Trp Cys Leu Gly Asn Glu Ser Arg 
                805                 810                 815     


Phe His Leu Asn Arg Ser Ala Ala Gly Trp Ala Arg Ser Ala Met Leu 
            820                 825                 830         


Arg Gly Leu Val Pro Gly Leu Leu Tyr Arg Thr Leu Val Ala Ala Ala 
        835                 840                 845             


Thr Ser Ala Gly Val Gly Val Pro Ser Ala Pro Val Leu Val Gln Leu 
    850                 855                 860                 


Pro Ser Pro Pro Asp Leu Glu Pro Gly Leu Glu Val Gly Ala Gly Leu 
865                 870                 875                 880 


Ala Val Arg Leu Ala Arg Val Leu Arg Glu Pro Ala Phe Leu Ala Gly 
                885                 890                 895     


Ser Gly Ala Ala Cys Gly Ala Leu Leu Leu Gly Leu Cys Ala Ala Leu 
            900                 905                 910         


Tyr Trp Arg Arg Lys Gln Arg Lys Glu Leu Ser His Tyr Thr Ala Ser 
        915                 920                 925             


Phe Ala Tyr Thr Pro Ala Val Ser Phe Pro His Ser Glu Gly Leu Ser 
    930                 935                 940                 


Gly Ala Ser Ser Arg Pro Pro Met Gly Leu Gly Pro Ala Pro Tyr Ser 
945                 950                 955                 960 


Trp Leu Ala Asp Ser Trp Pro His Pro Ser Arg Ser Pro Ser Ala Gln 
                965                 970                 975     


Glu Pro Arg Gly Ser Cys Cys Pro Ser Asn Pro Asp Pro Asp Asp Arg 
            980                 985                 990         


Tyr Tyr Asn Glu Ala Gly Ile Ser  Leu Tyr Leu Ala Gln  Thr Ala Arg 
        995                 1000                 1005             


Gly Thr  Ala Ala Pro Gly Glu  Gly Pro Val Tyr Ser  Thr Ile Asp 
    1010                 1015                 1020             


Pro Ala  Gly Glu Glu Leu Gln  Thr Phe His Gly Gly  Phe Pro Gln 
    1025                 1030                 1035             


His Pro  Ser Gly Asp Leu Gly  Pro Trp Ser Gln Tyr  Ala Pro Pro 
    1040                 1045                 1050             


Glu Trp  Ser Gln Gly Asp Ser  Gly Ala Lys Gly Gly  Lys Val Lys 
    1055                 1060                 1065             


Leu Leu  Gly Lys Pro Val Gln  Met Pro Ser Leu Asn  Trp Pro Glu 
    1070                 1075                 1080             


Ala Leu  Pro Pro Pro Pro Pro  Ser Cys Glu Leu Ser  Cys Leu Glu 
    1085                 1090                 1095             


Gly Pro  Glu Glu Glu Leu Glu  Gly Ser Ser Glu Pro  Glu Glu Trp 
    1100                 1105                 1110             


Cys Pro  Pro Met Pro Glu Arg  Ser His Leu Thr Glu  Pro Ser Ser 
    1115                 1120                 1125             


Ser Gly  Gly Cys Leu Val Thr  Pro Ser Arg Arg Glu  Thr Pro Ser 
    1130                 1135                 1140             


Pro Thr  Pro Ser Tyr Gly Gln  Gln Ser Thr Ala Thr  Leu Thr Pro 
    1145                 1150                 1155             


Ser Pro  Pro Asp Pro Pro Gln  Pro Pro Thr Asp Met  Pro His Leu 
    1160                 1165                 1170             


His Gln  Met Pro Arg Arg Val  Pro Leu Gly Pro Ser  Ser Pro Leu 
    1175                 1180                 1185             


Ser Val  Ser Gln Pro Met Leu  Gly Ile Arg Glu Ala  Arg Pro Ala 
    1190                 1195                 1200             


Gly Leu  Gly Ala Gly Pro Ala  Ala Ser Pro His Leu  Ser Pro Ser 
    1205                 1210                 1215             


Pro Ala  Pro Ser Thr Ala Ser  Ser Ala Pro Gly Arg  Thr Trp Gln 
    1220                 1225                 1230             


Gly Asn  Gly Glu Met Thr Pro  Pro Leu Gln Gly Pro  Arg Ala Arg 
    1235                 1240                 1245             


Phe Arg  Lys Lys Pro Lys Ala  Leu Pro Tyr Arg Arg  Glu Asn Ser 
    1250                 1255                 1260             


Pro Gly  Asp Leu Pro Pro Pro  Pro Leu Pro Pro Pro  Glu Glu Glu 
    1265                 1270                 1275             


Ala Ser  Trp Ala Leu Glu Leu  Arg Ala Ala Gly Ser  Met Ser Ser 
    1280                 1285                 1290             


Leu Glu  Arg Glu Arg Ser Gly  Glu Arg Lys Ala Val  Gln Ala Val 
    1295                 1300                 1305             


Pro Leu  Ala Ala Gln Arg Val  Leu His Pro Asp Glu  Glu Ala Trp 
    1310                 1315                 1320             


Leu Pro  Tyr Ser Arg Pro Ser  Phe Leu Ser Arg Gly  Gln Gly Thr 
    1325                 1330                 1335             


Ser Thr  Cys Ser Thr Ala Gly  Ser Asn Ser Ser Arg  Gly Ser Ser 
    1340                 1345                 1350             


Ser Ser  Arg Gly Ser Arg Gly  Pro Gly Arg Ser Arg  Ser Arg Ser 
    1355                 1360                 1365             


Gln Ser  Arg Ser Gln Ser Gln  Arg Pro Gly Gln Lys  Arg Arg Glu 
    1370                 1375                 1380             


Glu Pro  Arg 
    1385     


<210>  1390
<211>  217
<212>  PRT
<213>  Human

<400>  1390

Met Ser Ser Lys Val Ser Arg Asp Thr Leu Tyr Glu Ala Val Arg Glu 
1               5                   10                  15      


Val Leu His Gly Asn Gln Arg Lys Arg Arg Lys Phe Leu Glu Thr Val 
            20                  25                  30          


Glu Leu Gln Ile Ser Leu Lys Asn Tyr Asp Pro Gln Lys Asp Lys Arg 
        35                  40                  45              


Phe Ser Gly Thr Val Arg Leu Lys Ser Thr Pro Arg Pro Lys Phe Ser 
    50                  55                  60                  


Val Cys Val Leu Gly Asp Gln Gln His Cys Asp Glu Ala Lys Ala Val 
65                  70                  75                  80  


Asp Ile Pro His Met Asp Ile Glu Ala Leu Lys Lys Leu Asn Lys Asn 
                85                  90                  95      


Lys Lys Leu Val Lys Lys Leu Ala Lys Lys Tyr Asp Ala Phe Leu Ala 
            100                 105                 110         


Ser Glu Ser Leu Ile Lys Gln Ile Pro Arg Ile Leu Gly Pro Gly Leu 
        115                 120                 125             


Asn Lys Ala Gly Lys Phe Pro Ser Leu Leu Thr His Asn Glu Asn Met 
    130                 135                 140                 


Val Ala Lys Val Asp Glu Val Lys Ser Thr Ile Lys Phe Gln Met Lys 
145                 150                 155                 160 


Lys Val Leu Cys Leu Ala Val Ala Val Gly His Val Lys Met Thr Asp 
                165                 170                 175     


Asp Glu Leu Val Tyr Asn Ile His Leu Ala Val Asn Phe Leu Val Ser 
            180                 185                 190         


Leu Leu Lys Lys Asn Trp Gln Asn Val Arg Ala Leu Tyr Ile Lys Ser 
        195                 200                 205             


Thr Met Gly Lys Pro Gln Arg Leu Tyr 
    210                 215         


<210>  1391
<211>  157
<212>  PRT
<213>  Human

<400>  1391

Met Lys Val Glu Leu Cys Ser Phe Ser Gly Tyr Lys Ile Tyr Pro Gly 
1               5                   10                  15      


His Gly Arg Arg Tyr Ala Arg Thr Asp Gly Lys Val Phe Gln Phe Leu 
            20                  25                  30          


Asn Ala Lys Cys Glu Ser Ala Phe Leu Ser Lys Arg Asn Pro Arg Gln 
        35                  40                  45              


Ile Asn Trp Thr Val Leu Tyr Arg Arg Lys His Lys Lys Gly Gln Ser 
    50                  55                  60                  


Glu Glu Ile Gln Lys Lys Arg Thr Arg Arg Ala Val Lys Phe Gln Arg 
65                  70                  75                  80  


Ala Ile Thr Gly Ala Ser Leu Ala Asp Ile Met Ala Lys Arg Asn Gln 
                85                  90                  95      


Lys Pro Glu Val Arg Lys Ala Gln Arg Glu Gln Ala Ile Arg Ala Ala 
            100                 105                 110         


Lys Glu Ala Lys Lys Ala Lys Gln Ala Ser Lys Lys Thr Ala Met Ala 
        115                 120                 125             


Ala Ala Lys Ala Pro Thr Lys Ala Ala Pro Lys Gln Lys Ile Val Lys 
    130                 135                 140                 


Pro Val Lys Val Ser Ala Pro Arg Val Gly Gly Lys Arg 
145                 150                 155         


<210>  1392
<211>  116
<212>  PRT
<213>  Human

<400>  1392

Met Arg Gly Val Ala Glu Val Lys Glu Pro Cys Ser Leu Pro Met Leu 
1               5                   10                  15      


Ser Val Asp Met Glu Asn Lys Glu Asn Gly Ser Val Gly Val Lys Asn 
            20                  25                  30          


Ser Met Glu Asn Gly Arg Pro Pro Asp Pro Ala Asp Trp Ala Val Met 
        35                  40                  45              


Asp Val Val Asn Tyr Phe Arg Thr Val Gly Phe Glu Glu Gln Ala Ser 
    50                  55                  60                  


Ala Phe Gln Glu Gln Glu Ile Asp Gly Lys Ser Leu Leu Leu Met Thr 
65                  70                  75                  80  


Arg Asn Asp Val Leu Thr Gly Leu Gln Leu Lys Leu Gly Pro Ala Leu 
                85                  90                  95      


Lys Ile Tyr Glu Tyr His Val Lys Pro Leu Gln Thr Lys His Leu Lys 
            100                 105                 110         


Asn Asn Ser Ser 
        115     


<210>  1393
<211>  688
<212>  PRT
<213>  Human

<400>  1393

Met Gly Ser Glu Asn Ser Ala Leu Lys Ser Tyr Thr Leu Arg Glu Pro 
1               5                   10                  15      


Pro Phe Thr Leu Pro Ser Gly Leu Ala Val Tyr Pro Ala Val Leu Gln 
            20                  25                  30          


Asp Gly Lys Phe Ala Ser Val Phe Val Tyr Lys Arg Glu Asn Glu Asp 
        35                  40                  45              


Lys Val Asn Lys Ala Ala Lys His Leu Lys Thr Leu Arg His Pro Cys 
    50                  55                  60                  


Leu Leu Arg Phe Leu Ser Cys Thr Val Glu Ala Asp Gly Ile His Leu 
65                  70                  75                  80  


Val Thr Glu Arg Val Gln Pro Leu Glu Val Ala Leu Glu Thr Leu Ser 
                85                  90                  95      


Ser Ala Glu Val Cys Ala Gly Ile Tyr Asp Ile Leu Leu Ala Leu Ile 
            100                 105                 110         


Phe Leu His Asp Arg Gly His Leu Thr His Asn Asn Val Cys Leu Ser 
        115                 120                 125             


Ser Val Phe Val Ser Glu Asp Gly His Trp Lys Leu Gly Gly Met Glu 
    130                 135                 140                 


Thr Val Cys Lys Val Ser Gln Ala Thr Pro Glu Phe Leu Arg Ser Ile 
145                 150                 155                 160 


Gln Ser Ile Arg Asp Pro Ala Ser Ile Pro Pro Glu Glu Met Ser Pro 
                165                 170                 175     


Glu Phe Thr Thr Leu Pro Glu Cys His Gly His Ala Arg Asp Ala Phe 
            180                 185                 190         


Ser Phe Gly Thr Leu Val Glu Ser Leu Leu Thr Ile Leu Asn Glu Gln 
        195                 200                 205             


Val Ser Ala Asp Val Leu Ser Ser Phe Gln Gln Thr Leu His Ser Thr 
    210                 215                 220                 


Leu Leu Asn Pro Ile Pro Lys Cys Arg Pro Ala Leu Cys Thr Leu Leu 
225                 230                 235                 240 


Ser His Asp Phe Phe Arg Asn Asp Phe Leu Glu Val Val Asn Phe Leu 
                245                 250                 255     


Lys Ser Leu Thr Leu Lys Ser Glu Glu Glu Lys Thr Glu Phe Phe Lys 
            260                 265                 270         


Phe Leu Leu Asp Arg Val Ser Cys Leu Ser Glu Glu Leu Ile Ala Ser 
        275                 280                 285             


Arg Leu Val Pro Leu Leu Leu Asn Gln Leu Val Phe Ala Glu Pro Val 
    290                 295                 300                 


Ala Val Lys Ser Phe Leu Pro Tyr Leu Leu Gly Pro Lys Lys Asp His 
305                 310                 315                 320 


Ala Gln Gly Glu Thr Pro Cys Leu Leu Ser Pro Ala Leu Phe Gln Ser 
                325                 330                 335     


Arg Val Ile Pro Val Leu Leu Gln Leu Phe Glu Val His Glu Glu His 
            340                 345                 350         


Val Arg Met Val Leu Leu Ser His Ile Glu Ala Tyr Val Glu His Phe 
        355                 360                 365             


Thr Gln Glu Gln Leu Lys Lys Val Ile Leu Pro Gln Val Leu Leu Gly 
    370                 375                 380                 


Leu Arg Asp Thr Ser Asp Ser Ile Val Ala Ile Thr Leu His Ser Leu 
385                 390                 395                 400 


Ala Val Leu Val Ser Leu Leu Gly Pro Glu Val Val Val Gly Gly Glu 
                405                 410                 415     


Arg Thr Lys Ile Phe Lys Arg Thr Ala Pro Ser Phe Thr Lys Asn Thr 
            420                 425                 430         


Asp Leu Ser Leu Glu Gly Asp Pro Phe Ser Gln Pro Ile Lys Phe Pro 
        435                 440                 445             


Ile Asn Gly Leu Ser Asp Val Lys Asn Thr Ser Glu Asp Ser Glu Asn 
    450                 455                 460                 


Phe Pro Ser Ser Ser Lys Lys Ser Glu Glu Trp Pro Asp Trp Ser Glu 
465                 470                 475                 480 


Pro Glu Glu Pro Glu Asn Gln Thr Val Asn Ile Gln Ile Trp Pro Arg 
                485                 490                 495     


Glu Pro Cys Asp Asp Val Lys Ser Gln Cys Thr Thr Leu Asp Val Glu 
            500                 505                 510         


Glu Ser Ser Trp Asp Asp Cys Glu Pro Ser Ser Leu Asp Thr Lys Val 
        515                 520                 525             


Asn Pro Gly Gly Gly Ile Thr Ala Thr Lys Pro Val Thr Ser Gly Glu 
    530                 535                 540                 


Gln Lys Pro Ile Pro Ala Leu Leu Ser Leu Thr Glu Glu Ser Met Pro 
545                 550                 555                 560 


Trp Lys Ser Ser Leu Pro Gln Lys Ile Ser Leu Val Gln Arg Gly Asp 
                565                 570                 575     


Asp Ala Asp Gln Ile Glu Pro Pro Lys Val Ser Ser Gln Glu Arg Pro 
            580                 585                 590         


Leu Lys Val Pro Ser Glu Leu Gly Leu Gly Glu Glu Phe Thr Ile Gln 
        595                 600                 605             


Val Lys Lys Lys Pro Val Lys Asp Pro Glu Met Asp Trp Phe Ala Asp 
    610                 615                 620                 


Met Ile Pro Glu Ile Lys Pro Ser Ala Ala Phe Leu Ile Leu Pro Glu 
625                 630                 635                 640 


Leu Arg Thr Glu Met Val Pro Lys Lys Asp Asp Val Ser Pro Val Met 
                645                 650                 655     


Gln Phe Ser Ser Lys Phe Ala Ala Ala Glu Ile Thr Glu Gly Glu Ala 
            660                 665                 670         


Glu Gly Trp Glu Glu Glu Gly Glu Leu Asn Trp Glu Asp Asn Asn Trp 
        675                 680                 685             


<210>  1394
<211>  310
<212>  PRT
<213>  Human

<400>  1394

Met Arg Arg Ala Ala Leu Trp Leu Trp Leu Cys Ala Leu Ala Leu Ser 
1               5                   10                  15      


Leu Gln Pro Ala Leu Pro Gln Ile Val Ala Thr Asn Leu Pro Pro Glu 
            20                  25                  30          


Asp Gln Asp Gly Ser Gly Asp Asp Ser Asp Asn Phe Ser Gly Ser Gly 
        35                  40                  45              


Ala Gly Ala Leu Gln Asp Ile Thr Leu Ser Gln Gln Thr Pro Ser Thr 
    50                  55                  60                  


Trp Lys Asp Thr Gln Leu Leu Thr Ala Ile Pro Thr Ser Pro Glu Pro 
65                  70                  75                  80  


Thr Gly Leu Glu Ala Thr Ala Ala Ser Thr Ser Thr Leu Pro Ala Gly 
                85                  90                  95      


Glu Gly Pro Lys Glu Gly Glu Ala Val Val Leu Pro Glu Val Glu Pro 
            100                 105                 110         


Gly Leu Thr Ala Arg Glu Gln Glu Ala Thr Pro Arg Pro Arg Glu Thr 
        115                 120                 125             


Thr Gln Leu Pro Thr Thr His Gln Ala Ser Thr Thr Thr Ala Thr Thr 
    130                 135                 140                 


Ala Gln Glu Pro Ala Thr Ser His Pro His Arg Asp Met Gln Pro Gly 
145                 150                 155                 160 


His His Glu Thr Ser Thr Pro Ala Gly Pro Ser Gln Ala Asp Leu His 
                165                 170                 175     


Thr Pro His Thr Glu Asp Gly Gly Pro Ser Ala Thr Glu Arg Ala Ala 
            180                 185                 190         


Glu Asp Gly Ala Ser Ser Gln Leu Pro Ala Ala Glu Gly Ser Gly Glu 
        195                 200                 205             


Gln Asp Phe Thr Phe Glu Thr Ser Gly Glu Asn Thr Ala Val Val Ala 
    210                 215                 220                 


Val Glu Pro Asp Arg Arg Asn Gln Ser Pro Val Asp Gln Gly Ala Thr 
225                 230                 235                 240 


Gly Ala Ser Gln Gly Leu Leu Asp Arg Lys Glu Val Leu Gly Gly Val 
                245                 250                 255     


Ile Ala Gly Gly Leu Val Gly Leu Ile Phe Ala Val Cys Leu Val Gly 
            260                 265                 270         


Phe Met Leu Tyr Arg Met Lys Lys Lys Asp Glu Gly Ser Tyr Ser Leu 
        275                 280                 285             


Glu Glu Pro Lys Gln Ala Asn Gly Gly Ala Tyr Gln Lys Pro Thr Lys 
    290                 295                 300                 


Gln Glu Glu Phe Tyr Ala 
305                 310 


<210>  1395
<211>  493
<212>  PRT
<213>  Human

<400>  1395

Met Arg Arg Arg Arg Ala Ala Val Ala Ala Gly Phe Cys Ala Ser Phe 
1               5                   10                  15      


Leu Leu Gly Ser Val Leu Asn Val Leu Phe Ala Pro Gly Ser Glu Pro 
            20                  25                  30          


Pro Arg Pro Gly Gln Ser Pro Glu Pro Ser Pro Ala Pro Gly Pro Gly 
        35                  40                  45              


Arg Arg Gly Gly Arg Gly Glu Leu Ala Arg Gln Ile Arg Ala Arg Tyr 
    50                  55                  60                  


Glu Glu Val Gln Arg Tyr Ser Arg Gly Gly Pro Gly Pro Gly Ala Gly 
65                  70                  75                  80  


Arg Pro Glu Arg Arg Arg Leu Met Asp Leu Ala Pro Gly Gly Pro Gly 
                85                  90                  95      


Leu Pro Arg Pro Arg Pro Pro Trp Ala Arg Pro Leu Ser Asp Gly Ala 
            100                 105                 110         


Pro Gly Trp Pro Pro Ala Pro Gly Pro Gly Ser Pro Gly Pro Gly Pro 
        115                 120                 125             


Arg Leu Gly Cys Ala Ala Leu Arg Asn Val Ser Gly Ala Gln Tyr Met 
    130                 135                 140                 


Gly Ser Gly Tyr Thr Lys Ala Val Tyr Arg Val Arg Leu Pro Gly Gly 
145                 150                 155                 160 


Ala Ala Val Ala Leu Lys Ala Val Asp Phe Ser Gly His Asp Leu Gly 
                165                 170                 175     


Ser Cys Val Arg Glu Phe Gly Val Arg Arg Gly Cys Tyr Arg Leu Ala 
            180                 185                 190         


Ala His Lys Leu Leu Lys Glu Met Val Leu Leu Glu Arg Leu Arg His 
        195                 200                 205             


Pro Asn Val Leu Gln Leu Tyr Gly Tyr Cys Tyr Gln Asp Ser Glu Asp 
    210                 215                 220                 


Ile Pro Asp Thr Leu Thr Thr Ile Thr Glu Leu Gly Ala Pro Val Glu 
225                 230                 235                 240 


Met Ile Gln Leu Leu Gln Thr Ser Trp Glu Asp Arg Phe Arg Ile Cys 
                245                 250                 255     


Leu Ser Leu Gly Arg Leu Leu His His Leu Ala His Ser Pro Leu Gly 
            260                 265                 270         


Ser Val Thr Leu Leu Asp Phe Arg Pro Arg Gln Phe Val Leu Val Asp 
        275                 280                 285             


Gly Glu Leu Lys Val Thr Asp Leu Asp Asp Ala Arg Val Glu Glu Thr 
    290                 295                 300                 


Pro Cys Ala Gly Ser Thr Asp Cys Ile Leu Glu Phe Pro Ala Arg Asn 
305                 310                 315                 320 


Phe Thr Leu Pro Cys Ser Ala Gln Gly Trp Cys Glu Gly Met Asn Glu 
                325                 330                 335     


Lys Arg Asn Leu Tyr Asn Ala Tyr Arg Phe Phe Phe Thr Tyr Leu Leu 
            340                 345                 350         


Pro His Ser Ala Pro Pro Ser Leu Arg Pro Leu Leu Asp Ser Ile Val 
        355                 360                 365             


Asn Ala Thr Gly Glu Leu Ala Trp Gly Val Asp Glu Thr Leu Ala Gln 
    370                 375                 380                 


Leu Glu Lys Val Leu His Leu Tyr Arg Ser Gly Gln Tyr Leu Gln Asn 
385                 390                 395                 400 


Ser Thr Ala Ser Ser Ser Thr Glu Tyr Gln Cys Ile Pro Asp Ser Thr 
                405                 410                 415     


Ile Pro Gln Glu Asp Tyr Arg Cys Trp Pro Ser Tyr His His Gly Ser 
            420                 425                 430         


Cys Leu Leu Ser Val Phe Asn Leu Ala Glu Ala Val Asp Val Cys Glu 
        435                 440                 445             


Ser His Ala Gln Cys Arg Ala Phe Val Val Thr Asn Gln Thr Thr Trp 
    450                 455                 460                 


Thr Gly Arg Gln Leu Val Phe Phe Lys Thr Gly Trp Ser Gln Val Val 
465                 470                 475                 480 


Pro Asp Pro Asn Lys Thr Thr Tyr Val Lys Ala Ser Gly 
                485                 490             


<210>  1396
<211>  313
<212>  PRT
<213>  Human

<400>  1396

Met Asp Asn Lys Lys Arg Leu Ala Tyr Ala Ile Ile Gln Phe Leu His 
1               5                   10                  15      


Asp Gln Leu Arg His Gly Gly Leu Ser Ser Asp Ala Gln Glu Ser Leu 
            20                  25                  30          


Glu Val Ala Ile Gln Cys Leu Glu Thr Ala Phe Gly Val Thr Val Glu 
        35                  40                  45              


Asp Ser Asp Leu Ala Leu Pro Gln Thr Leu Pro Glu Ile Phe Glu Ala 
    50                  55                  60                  


Ala Ala Thr Gly Lys Glu Met Pro Gln Asp Leu Arg Ser Pro Ala Arg 
65                  70                  75                  80  


Thr Pro Pro Ser Glu Glu Asp Ser Ala Glu Ala Glu Arg Leu Lys Thr 
                85                  90                  95      


Glu Gly Asn Glu Gln Met Lys Val Glu Asn Phe Glu Ala Ala Val His 
            100                 105                 110         


Phe Tyr Gly Lys Ala Ile Glu Leu Asn Pro Ala Asn Ala Val Tyr Phe 
        115                 120                 125             


Cys Asn Arg Ala Ala Ala Tyr Ser Lys Leu Gly Asn Tyr Ala Gly Ala 
    130                 135                 140                 


Val Gln Asp Cys Glu Arg Ala Ile Cys Ile Asp Pro Ala Tyr Ser Lys 
145                 150                 155                 160 


Ala Tyr Gly Arg Met Gly Leu Ala Leu Ser Ser Leu Asn Lys His Val 
                165                 170                 175     


Glu Ala Val Ala Tyr Tyr Lys Lys Ala Leu Glu Leu Asp Pro Asp Asn 
            180                 185                 190         


Glu Thr Tyr Lys Ser Asn Leu Lys Ile Ala Glu Leu Lys Leu Arg Glu 
        195                 200                 205             


Ala Pro Ser Pro Thr Gly Gly Val Gly Ser Phe Asp Ile Ala Gly Leu 
    210                 215                 220                 


Leu Asn Asn Pro Gly Phe Met Ser Met Ala Ser Asn Leu Met Asn Asn 
225                 230                 235                 240 


Pro Gln Ile Gln Gln Leu Met Ser Gly Met Ile Ser Gly Gly Asn Asn 
                245                 250                 255     


Pro Leu Gly Thr Pro Gly Thr Ser Pro Ser Gln Asn Asp Leu Ala Ser 
            260                 265                 270         


Leu Ile Gln Ala Gly Gln Gln Phe Ala Gln Gln Met Gln Gln Gln Asn 
        275                 280                 285             


Pro Glu Leu Ile Glu Gln Leu Arg Ser Gln Ile Arg Ser Arg Thr Pro 
    290                 295                 300                 


Ser Ala Ser Asn Asp Asp Gln Gln Glu 
305                 310             


<210>  1397
<211>  919
<212>  PRT
<213>  Human

<400>  1397

Met Glu Ala Pro Glu Tyr Leu Asp Leu Asp Glu Ile Asp Phe Ser Asp 
1               5                   10                  15      


Asp Ile Ser Tyr Ser Val Thr Ser Leu Lys Thr Ile Pro Glu Leu Cys 
            20                  25                  30          


Arg Arg Cys Asp Thr Gln Asn Glu Asp Arg Ser Val Ser Ser Ser Ser 
        35                  40                  45              


Trp Asn Cys Gly Ile Ser Thr Leu Ile Thr Asn Thr Gln Lys Pro Thr 
    50                  55                  60                  


Gly Ile Ala Asp Val Tyr Ser Lys Phe Arg Pro Val Lys Arg Val Ser 
65                  70                  75                  80  


Pro Leu Lys His Gln Pro Glu Thr Leu Glu Asn Asn Glu Ser Asp Asp 
                85                  90                  95      


Gln Lys Asn Gln Lys Val Val Glu Tyr Gln Lys Gly Gly Glu Ser Asp 
            100                 105                 110         


Leu Gly Pro Gln Pro Gln Glu Leu Gly Pro Gly Asp Gly Val Gly Gly 
        115                 120                 125             


Pro Pro Gly Lys Ser Ser Glu Pro Ser Thr Ser Leu Gly Glu Leu Glu 
    130                 135                 140                 


His Tyr Asp Leu Asp Met Asp Glu Ile Leu Asp Val Pro Tyr Ile Lys 
145                 150                 155                 160 


Ser Ser Gln Gln Leu Ala Ser Phe Thr Lys Val Thr Ser Glu Lys Arg 
                165                 170                 175     


Ile Leu Gly Leu Cys Thr Thr Ile Asn Gly Leu Ser Gly Lys Ala Cys 
            180                 185                 190         


Ser Thr Gly Ser Ser Glu Ser Ser Ser Ser Asn Met Ala Pro Phe Cys 
        195                 200                 205             


Val Leu Ser Pro Val Lys Ser Pro His Leu Arg Lys Ala Ser Ala Val 
    210                 215                 220                 


Ile His Asp Gln His Lys Leu Ser Thr Glu Glu Thr Glu Ile Ser Pro 
225                 230                 235                 240 


Pro Leu Val Lys Cys Gly Ser Ala Tyr Glu Pro Glu Asn Gln Ser Lys 
                245                 250                 255     


Asp Phe Leu Asn Lys Thr Phe Ser Asp Pro His Gly Arg Lys Val Glu 
            260                 265                 270         


Lys Thr Thr Pro Asp Cys Gln Leu Arg Ala Phe His Leu Gln Ser Ser 
        275                 280                 285             


Ala Ala Glu Ser Lys Pro Glu Glu Gln Val Ser Gly Leu Asn Arg Thr 
    290                 295                 300                 


Ser Ser Gln Gly Pro Glu Glu Arg Ser Glu Tyr Leu Lys Lys Val Lys 
305                 310                 315                 320 


Ser Ile Leu Asn Ile Val Lys Glu Gly Gln Ile Ser Leu Leu Pro His 
                325                 330                 335     


Leu Ala Ala Asp Asn Leu Asp Lys Ile His Asp Glu Asn Gly Asn Asn 
            340                 345                 350         


Leu Leu His Ile Ala Ala Ser Gln Gly His Ala Glu Cys Leu Gln His 
        355                 360                 365             


Leu Thr Ser Leu Met Gly Glu Asp Cys Leu Asn Glu Arg Asn Thr Glu 
    370                 375                 380                 


Lys Leu Thr Pro Ala Gly Leu Ala Ile Lys Asn Gly Gln Leu Glu Cys 
385                 390                 395                 400 


Val Arg Trp Met Val Ser Glu Thr Glu Ala Ile Ala Glu Leu Ser Cys 
                405                 410                 415     


Ser Lys Asp Phe Pro Ser Leu Ile His Tyr Ala Gly Cys Tyr Gly Gln 
            420                 425                 430         


Glu Lys Ile Leu Leu Trp Leu Leu Gln Phe Met Gln Glu Gln Gly Ile 
        435                 440                 445             


Ser Leu Asp Glu Val Asp Gln Asp Gly Asn Ser Ala Val His Val Ala 
    450                 455                 460                 


Ser Gln His Gly Tyr Leu Gly Cys Ile Gln Thr Leu Val Glu Tyr Gly 
465                 470                 475                 480 


Ala Asn Val Thr Met Gln Asn His Ala Gly Glu Lys Pro Ser Gln Ser 
                485                 490                 495     


Ala Glu Arg Gln Gly His Thr Leu Cys Ser Arg Tyr Leu Val Val Val 
            500                 505                 510         


Glu Thr Cys Met Ser Leu Ala Ser Gln Val Val Lys Leu Thr Lys Gln 
        515                 520                 525             


Leu Lys Glu Gln Thr Val Glu Arg Val Thr Leu Gln Asn Gln Leu Gln 
    530                 535                 540                 


Gln Phe Leu Glu Ala Gln Lys Ser Glu Gly Lys Ser Leu Pro Ser Ser 
545                 550                 555                 560 


Pro Ser Ser Pro Ser Ser Pro Ala Ser Arg Lys Ser Gln Trp Lys Ser 
                565                 570                 575     


Pro Asp Ala Asp Asp Asp Ser Val Ala Lys Ser Lys Pro Gly Val Gln 
            580                 585                 590         


Glu Gly Ile Gln Val Leu Gly Ser Leu Ser Ala Ser Ser Arg Ala Arg 
        595                 600                 605             


Pro Lys Ala Lys Asp Glu Asp Ser Asp Lys Ile Leu Arg Gln Leu Leu 
    610                 615                 620                 


Gly Lys Glu Ile Ser Glu Asn Val Cys Thr Gln Glu Lys Leu Ser Leu 
625                 630                 635                 640 


Glu Phe Gln Asp Ala Gln Ala Ser Ser Arg Asn Ser Lys Lys Ile Pro 
                645                 650                 655     


Leu Glu Lys Arg Glu Leu Lys Leu Ala Arg Leu Arg Gln Leu Met Gln 
            660                 665                 670         


Arg Ser Leu Ser Glu Ser Asp Thr Asp Ser Asn Asn Ser Glu Asp Pro 
        675                 680                 685             


Lys Thr Thr Pro Val Arg Lys Ala Asp Arg Pro Arg Pro Gln Pro Ile 
    690                 695                 700                 


Val Glu Ser Val Glu Ser Met Asp Ser Ala Glu Ser Leu His Leu Met 
705                 710                 715                 720 


Ile Lys Lys His Thr Leu Ala Ser Gly Gly Arg Arg Phe Pro Phe Ser 
                725                 730                 735     


Ile Lys Ala Ser Lys Ser Leu Asp Gly His Ser Pro Ser Pro Thr Ser 
            740                 745                 750         


Glu Ser Ser Glu Pro Asp Leu Glu Ser Gln Tyr Pro Gly Ser Gly Ser 
        755                 760                 765             


Ile Pro Pro Asn Gln Pro Ser Gly Asp Pro Gln Gln Pro Ser Pro Asp 
    770                 775                 780                 


Ser Thr Ala Ala Gln Lys Val Ala Thr Ser Pro Lys Ser Ala Leu Lys 
785                 790                 795                 800 


Ser Pro Ser Ser Lys Arg Arg Thr Ser Gln Asn Leu Lys Leu Arg Val 
                805                 810                 815     


Thr Phe Glu Glu Pro Val Val Gln Met Glu Gln Pro Ser Leu Glu Leu 
            820                 825                 830         


Asn Gly Glu Lys Asp Lys Asp Lys Gly Arg Thr Leu Gln Arg Thr Ser 
        835                 840                 845             


Thr Ser Asn Glu Ser Gly Asp Gln Leu Lys Arg Pro Phe Gly Ala Phe 
    850                 855                 860                 


Arg Ser Ile Met Glu Thr Leu Ser Gly Asn Gln Asn Asn Asn Asn Asn 
865                 870                 875                 880 


Tyr Gln Ala Ala Asn Gln Leu Lys Thr Ser Thr Leu Pro Leu Thr Ser 
                885                 890                 895     


Leu Gly Arg Lys Thr Asp Ala Lys Gly Asn Pro Ala Ser Ser Ala Ser 
            900                 905                 910         


Lys Gly Lys Asn Lys Ala Ala 
        915                 


<210>  1398
<211>  227
<212>  PRT
<213>  Human

<400>  1398

Met Ala Asp Leu Leu Gly Ser Ile Leu Ser Ser Met Glu Lys Pro Pro 
1               5                   10                  15      


Ser Leu Gly Asp Gln Glu Thr Arg Arg Lys Ala Arg Glu Gln Ala Ala 
            20                  25                  30          


Arg Leu Lys Lys Leu Gln Glu Gln Glu Lys Gln Gln Lys Val Glu Phe 
        35                  40                  45              


Arg Lys Arg Met Glu Lys Glu Val Ser Asp Phe Ile Gln Asp Ser Gly 
    50                  55                  60                  


Gln Ile Lys Lys Lys Phe Gln Pro Met Asn Lys Ile Glu Arg Ser Ile 
65                  70                  75                  80  


Leu His Asp Val Val Glu Val Ala Gly Leu Thr Ser Phe Ser Phe Gly 
                85                  90                  95      


Glu Asp Asp Asp Cys Arg Tyr Val Met Ile Phe Lys Lys Glu Phe Ala 
            100                 105                 110         


Pro Ser Asp Glu Glu Leu Asp Ser Tyr Arg Arg Gly Glu Glu Trp Asp 
        115                 120                 125             


Pro Gln Lys Ala Glu Glu Lys Arg Lys Leu Lys Glu Leu Ala Gln Arg 
    130                 135                 140                 


Gln Glu Glu Glu Ala Ala Gln Gln Gly Pro Val Val Val Ser Pro Ala 
145                 150                 155                 160 


Ser Asp Tyr Lys Asp Lys Tyr Ser His Leu Ile Gly Lys Gly Ala Ala 
                165                 170                 175     


Lys Asp Ala Ala His Met Leu Gln Ala Asn Lys Thr Tyr Gly Cys Val 
            180                 185                 190         


Pro Val Ala Asn Lys Arg Asp Thr Arg Ser Ile Glu Glu Ala Met Asn 
        195                 200                 205             


Glu Ile Arg Ala Lys Lys Arg Leu Arg Gln Ser Gly Glu Glu Leu Pro 
    210                 215                 220                 


Pro Thr Ser 
225         


<210>  1399
<211>  1085
<212>  PRT
<213>  Human

<400>  1399

Met Ser Thr Pro Ser Arg Phe Lys Lys Asp Lys Glu Ile Ile Ala Glu 
1               5                   10                  15      


Tyr Glu Ser Gln Val Lys Glu Ile Arg Ala Gln Leu Val Glu Gln Gln 
            20                  25                  30          


Lys Cys Leu Glu Gln Gln Thr Glu Met Arg Val Gln Leu Leu Gln Asp 
        35                  40                  45              


Leu Gln Asp Phe Phe Arg Lys Lys Ala Glu Ile Glu Thr Glu Tyr Ser 
    50                  55                  60                  


Arg Asn Leu Glu Lys Leu Ala Glu Arg Phe Met Ala Lys Thr Arg Ser 
65                  70                  75                  80  


Thr Lys Asp His Gln Gln Tyr Lys Lys Asp Gln Asn Leu Leu Ser Pro 
                85                  90                  95      


Val Asn Cys Trp Tyr Leu Leu Leu Asn Gln Val Arg Arg Glu Ser Lys 
            100                 105                 110         


Asp His Ala Thr Leu Ser Asp Ile Tyr Leu Asn Asn Val Ile Met Arg 
        115                 120                 125             


Phe Met Gln Ile Ser Glu Asp Ser Thr Arg Met Phe Lys Lys Ser Lys 
    130                 135                 140                 


Glu Ile Ala Phe Gln Leu His Glu Asp Leu Met Lys Val Leu Asn Glu 
145                 150                 155                 160 


Leu Tyr Thr Val Met Lys Thr Tyr His Met Tyr His Ala Glu Ser Ile 
                165                 170                 175     


Ser Ala Glu Ser Lys Leu Lys Glu Ala Glu Lys Gln Glu Glu Lys Gln 
            180                 185                 190         


Ile Gly Arg Ser Gly Asp Pro Val Phe His Ile Arg Leu Glu Glu Arg 
        195                 200                 205             


His Gln Arg Arg Ser Ser Val Lys Lys Ile Glu Lys Met Lys Glu Lys 
    210                 215                 220                 


Arg Gln Ala Lys Tyr Ser Glu Asn Lys Leu Lys Ser Ile Lys Ala Arg 
225                 230                 235                 240 


Asn Glu Tyr Leu Leu Thr Leu Glu Ala Thr Asn Ala Ser Val Phe Lys 
                245                 250                 255     


Tyr Tyr Ile His Asp Leu Ser Asp Leu Ile Asp Cys Cys Asp Leu Gly 
            260                 265                 270         


Tyr His Ala Ser Leu Asn Arg Ala Leu Arg Thr Tyr Leu Ser Ala Glu 
        275                 280                 285             


Tyr Asn Leu Glu Thr Ser Arg His Glu Gly Leu Asp Ile Ile Glu Asn 
    290                 295                 300                 


Ala Val Asp Asn Leu Glu Pro Arg Ser Asp Lys Gln Arg Phe Met Glu 
305                 310                 315                 320 


Met Tyr Pro Ala Ala Phe Cys Pro Pro Met Lys Phe Glu Phe Gln Ser 
                325                 330                 335     


His Met Gly Asp Glu Val Cys Gln Val Ser Ala Gln Gln Pro Val Gln 
            340                 345                 350         


Ala Glu Leu Met Leu Arg Tyr Gln Gln Leu Gln Ser Arg Leu Ala Thr 
        355                 360                 365             


Leu Lys Ile Glu Asn Glu Glu Val Lys Lys Thr Thr Glu Ala Thr Leu 
    370                 375                 380                 


Gln Thr Ile Gln Asp Met Val Thr Ile Glu Asp Tyr Asp Val Ser Glu 
385                 390                 395                 400 


Cys Phe Gln His Ser Arg Ser Thr Glu Ser Val Lys Ser Thr Val Ser 
                405                 410                 415     


Glu Thr Tyr Leu Ser Lys Pro Ser Ile Ala Lys Arg Arg Ala Asn Gln 
            420                 425                 430         


Gln Glu Thr Glu Gln Phe Tyr Phe Met Lys Leu Arg Glu Tyr Leu Glu 
        435                 440                 445             


Gly Ser Asn Leu Ile Thr Lys Leu Gln Ala Lys His Asp Leu Leu Gln 
    450                 455                 460                 


Arg Thr Leu Gly Glu Gly His Arg Ala Glu Tyr Met Thr Thr Arg Pro 
465                 470                 475                 480 


Pro Asn Val Pro Pro Lys Pro Gln Lys His Arg Lys Ser Arg Pro Arg 
                485                 490                 495     


Ser Gln Tyr Asn Thr Lys Leu Phe Asn Gly Asp Leu Glu Thr Phe Val 
            500                 505                 510         


Lys Asp Ser Gly Gln Val Ile Pro Leu Ile Val Glu Ser Cys Ile Arg 
        515                 520                 525             


Phe Ile Asn Leu Tyr Gly Leu Gln His Gln Gly Ile Phe Arg Val Ser 
    530                 535                 540                 


Gly Ser Gln Val Glu Val Asn Asp Ile Lys Asn Ser Phe Glu Arg Gly 
545                 550                 555                 560 


Glu Asn Pro Leu Ala Asp Asp Gln Ser Asn His Asp Ile Asn Ser Val 
                565                 570                 575     


Ala Gly Val Leu Lys Leu Tyr Phe Arg Gly Leu Glu Asn Pro Leu Phe 
            580                 585                 590         


Pro Lys Glu Arg Phe Asn Asp Leu Ile Ser Cys Ile Arg Ile Asp Asn 
        595                 600                 605             


Leu Tyr Glu Arg Ala Leu His Ile Arg Lys Leu Leu Leu Thr Leu Pro 
    610                 615                 620                 


Arg Ser Val Leu Ile Val Met Arg Tyr Leu Phe Ala Phe Leu Asn His 
625                 630                 635                 640 


Leu Ser Gln Tyr Ser Asp Glu Asn Met Met Asp Pro Tyr Asn Leu Ala 
                645                 650                 655     


Ile Cys Phe Gly Pro Thr Leu Met Pro Val Pro Glu Ile Gln Asp Gln 
            660                 665                 670         


Val Ser Cys Gln Ala His Val Asn Glu Ile Ile Lys Thr Ile Ile Ile 
        675                 680                 685             


His His Glu Thr Ile Phe Pro Asp Ala Lys Glu Leu Asp Gly Pro Val 
    690                 695                 700                 


Tyr Glu Lys Cys Met Ala Gly Asp Asp Tyr Cys Asp Ser Pro Tyr Ser 
705                 710                 715                 720 


Glu His Gly Thr Leu Glu Glu Val Asp Gln Asp Ala Gly Thr Glu Pro 
                725                 730                 735     


His Thr Ser Glu Asp Glu Cys Glu Pro Ile Glu Ala Ile Ala Lys Phe 
            740                 745                 750         


Asp Tyr Val Gly Arg Ser Ala Arg Glu Leu Ser Phe Lys Lys Gly Ala 
        755                 760                 765             


Ser Leu Leu Leu Tyr His Arg Ala Ser Glu Asp Trp Trp Glu Gly Arg 
    770                 775                 780                 


His Asn Gly Ile Asp Gly Leu Val Pro His Gln Tyr Ile Val Val Gln 
785                 790                 795                 800 


Asp Met Asp Asp Thr Phe Ser Asp Thr Leu Ser Gln Lys Ala Asp Ser 
                805                 810                 815     


Glu Ala Ser Ser Gly Pro Val Thr Glu Asp Lys Ser Ser Ser Lys Asp 
            820                 825                 830         


Met Asn Ser Pro Thr Asp Arg His Pro Asp Gly Tyr Leu Ala Arg Gln 
        835                 840                 845             


Arg Lys Arg Gly Glu Pro Pro Pro Pro Val Arg Arg Pro Gly Arg Thr 
    850                 855                 860                 


Ser Asp Gly His Cys Pro Leu His Pro Pro His Ala Leu Ser Asn Ser 
865                 870                 875                 880 


Ser Val Asp Leu Gly Ser Pro Ser Leu Ala Ser His Pro Arg Gly Leu 
                885                 890                 895     


Leu Gln Asn Arg Gly Leu Asn Asn Asp Ser Pro Glu Arg Arg Arg Arg 
            900                 905                 910         


Pro Gly His Gly Ser Leu Thr Asn Ile Ser Arg His Asp Ser Leu Lys 
        915                 920                 925             


Lys Ile Asp Ser Pro Pro Ile Arg Arg Ser Thr Ser Ser Gly Gln Tyr 
    930                 935                 940                 


Thr Gly Phe Asn Asp His Lys Pro Leu Asp Pro Glu Thr Ile Ala Gln 
945                 950                 955                 960 


Asp Ile Glu Glu Thr Met Asn Thr Ala Leu Asn Glu Leu Arg Glu Leu 
                965                 970                 975     


Glu Arg Gln Ser Thr Ala Lys His Ala Pro Asp Val Val Leu Asp Thr 
            980                 985                 990         


Leu Glu Gln Val Lys Asn Ser Pro  Thr Pro Ala Thr Ser  Thr Glu Ser 
        995                 1000                 1005             


Leu Ser  Pro Leu His Asn Val  Ala Leu Arg Ser Ser  Glu Pro Gln 
    1010                 1015                 1020             


Ile Arg  Arg Ser Thr Ser Ser  Ser Ser Asp Thr Met  Ser Thr Phe 
    1025                 1030                 1035             


Lys Pro  Met Val Ala Pro Arg  Met Gly Val Gln Leu  Lys Pro Pro 
    1040                 1045                 1050             


Ala Leu  Arg Pro Lys Pro Ala  Val Leu Pro Lys Thr  Asn Pro Thr 
    1055                 1060                 1065             


Ile Gly  Pro Ala Pro Pro Pro  Gln Gly Pro Thr Asp  Lys Ser Cys 
    1070                 1075                 1080             


Thr Met  
    1085 


<210>  1400
<211>  1259
<212>  PRT
<213>  Human

<400>  1400

Met Asp Arg Pro Leu Ser Ser Ser Ala Glu Ala Glu Glu Glu Leu Glu 
1               5                   10                  15      


Trp Gln Val Ala Ser Arg Arg Arg Lys Ala Trp Ala Lys Cys Arg Ser 
            20                  25                  30          


Ser Trp Gln Ala Ser Glu Thr Glu Asp Leu Ser Thr Glu Ala Thr Thr 
        35                  40                  45              


Gln Asp Glu Glu Glu Asp Glu Glu Glu Asp Leu Pro Gly Ala Gln Leu 
    50                  55                  60                  


Pro Ala Ala Gly Gly Arg Gly Asn Val Pro Asn Glu Lys Ile Ala Ile 
65                  70                  75                  80  


Trp Leu Lys Asp Cys Arg Thr Pro Leu Gly Ala Ser Leu Asp Glu Gln 
                85                  90                  95      


Ser Ser Ser Thr Leu Lys Gly Val Leu Val Arg Asn Gly Gly Ser Phe 
            100                 105                 110         


Glu Asp Asp Leu Ser Leu Gly Ala Glu Ala Asn His Leu His Glu Ser 
        115                 120                 125             


Asp Ala Gln Ile Glu Asn Cys Asn Asn Ile Leu Ala Lys Glu Arg Arg 
    130                 135                 140                 


Leu Gln Phe His Gln Lys Gly Arg Ser Met Asn Ser Thr Gly Ser Gly 
145                 150                 155                 160 


Lys Ser Ser Gly Thr Val Ser Ser Val Ser Glu Leu Leu Glu Leu Tyr 
                165                 170                 175     


Glu Glu Asp Pro Glu Glu Ile Leu Tyr Asn Leu Gly Phe Gly Arg Asp 
            180                 185                 190         


Glu Pro Asp Ile Ala Ser Lys Ile Pro Ser Arg Phe Phe Asn Ser Ser 
        195                 200                 205             


Ser Phe Ala Lys Gly Ile Asp Ile Lys Val Phe Leu Ser Ala Gln Met 
    210                 215                 220                 


Gln Arg Met Glu Val Glu Asn Pro Asn Tyr Ala Leu Thr Ser Arg Phe 
225                 230                 235                 240 


Arg Gln Ile Glu Val Leu Thr Thr Val Ala Asn Ala Phe Ser Ser Leu 
                245                 250                 255     


Tyr Ser Gln Val Ser Gly Thr Pro Leu Gln Arg Ile Gly Ser Met Ser 
            260                 265                 270         


Ser Val Thr Ser Asn Lys Glu Thr Asp Pro Pro Pro Pro Leu Thr Arg 
        275                 280                 285             


Ser Asn Thr Ala Asn Arg Leu Met Lys Thr Leu Ser Lys Leu Asn Leu 
    290                 295                 300                 


Cys Val Asp Lys Thr Glu Lys Gly Glu Ser Ser Ser Pro Ser Pro Ser 
305                 310                 315                 320 


Ala Glu Lys Gly Lys Ile Leu Asn Val Ser Val Ile Glu Glu Ser Gly 
                325                 330                 335     


Asn Lys Asn Asp Gln Lys Ser Gln Lys Ile Met Lys Lys Lys Glu Ser 
            340                 345                 350         


Ser Ser Met Leu Ala Thr Val Lys Glu Glu Val Ser Gly Ser Ser Ala 
        355                 360                 365             


Ala Val Thr Glu Asn Ala Asp Ser Asp Arg Ile Ser Asp Glu Ala Asn 
    370                 375                 380                 


Ser Asn Phe Asn Gln Gly Thr Glu Asn Glu Gln Ser Lys Glu Thr Gln 
385                 390                 395                 400 


Ser His Glu Ser Lys Leu Gly Glu Glu Ser Gly Ile Val Glu Ser Lys 
                405                 410                 415     


Leu Asp Ser Asp Phe Asn Ile Ser Ser His Ser Glu Leu Glu Asn Ser 
            420                 425                 430         


Ser Glu Leu Lys Ser Val His Ile Ser Thr Pro Glu Lys Glu Pro Cys 
        435                 440                 445             


Ala Pro Leu Thr Ile Pro Ser Ile Arg Asn Ile Met Thr Gln Gln Lys 
    450                 455                 460                 


Asp Ser Phe Glu Met Glu Glu Val Gln Ser Thr Glu Gly Glu Ala Pro 
465                 470                 475                 480 


His Val Pro Ala Thr Tyr Gln Leu Gly Leu Thr Lys Ser Lys Arg Asp 
                485                 490                 495     


His Leu Leu Arg Thr Ala Ser Gln His Ser Asp Ser Ser Gly Phe Ala 
            500                 505                 510         


Glu Asp Ser Thr Asp Cys Leu Ser Leu Asn His Leu Gln Val Gln Glu 
        515                 520                 525             


Ser Leu Gln Ala Met Gly Ser Ser Ala Asp Ser Cys Asp Ser Glu Thr 
    530                 535                 540                 


Thr Val Thr Ser Leu Gly Glu Asp Leu Ala Thr Pro Thr Ala Gln Asp 
545                 550                 555                 560 


Gln Pro Tyr Phe Asn Glu Ser Glu Glu Glu Ser Leu Val Pro Leu Gln 
                565                 570                 575     


Lys Gly Leu Glu Lys Ala Ala Ala Val Ala Asp Lys Arg Lys Ser Gly 
            580                 585                 590         


Ser Gln Asp Phe Pro Gln Cys Asn Thr Ile Glu Asn Thr Gly Thr Lys 
        595                 600                 605             


Gln Ser Thr Cys Ser Pro Gly Asp His Ile Ile Glu Ile Thr Glu Val 
    610                 615                 620                 


Glu Glu Asp Leu Phe Pro Ala Glu Thr Val Glu Leu Leu Arg Glu Ala 
625                 630                 635                 640 


Ser Ala Glu Ser Asp Val Gly Lys Ser Ser Glu Ser Glu Phe Thr Gln 
                645                 650                 655     


Tyr Thr Thr His His Ile Leu Lys Ser Leu Ala Ser Ile Glu Ala Lys 
            660                 665                 670         


Cys Ser Asp Met Ser Ser Glu Asn Thr Thr Gly Pro Pro Ser Ser Met 
        675                 680                 685             


Asp Arg Val Asn Thr Ala Leu Gln Arg Ala Gln Met Lys Val Cys Ser 
    690                 695                 700                 


Leu Ser Asn Gln Arg Met Gly Arg Ser Leu Leu Lys Ser Lys Asp Leu 
705                 710                 715                 720 


Leu Lys Gln Arg Tyr Leu Phe Ala Lys Ala Gly Tyr Pro Leu Arg Arg 
                725                 730                 735     


Ser Gln Ser Leu Pro Thr Thr Leu Leu Ser Pro Val Arg Val Val Ser 
            740                 745                 750         


Ser Val Asn Val Arg Leu Ser Pro Gly Lys Glu Thr Arg Cys Ser Pro 
        755                 760                 765             


Pro Ser Phe Thr Tyr Lys Tyr Thr Pro Glu Glu Glu Gln Glu Leu Glu 
    770                 775                 780                 


Lys Arg Val Met Glu His Asp Gly Gln Ser Leu Val Lys Ser Thr Ile 
785                 790                 795                 800 


Phe Ile Ser Pro Ser Ser Val Lys Lys Glu Glu Ala Pro Gln Ser Glu 
                805                 810                 815     


Ala Pro Arg Val Glu Glu Cys His His Gly Arg Thr Pro Thr Cys Ser 
            820                 825                 830         


Arg Leu Ala Pro Pro Pro Met Ser Gln Ser Thr Cys Ser Leu His Ser 
        835                 840                 845             


Ile His Ser Glu Trp Gln Glu Arg Pro Leu Cys Glu His Thr Arg Thr 
    850                 855                 860                 


Leu Ser Thr His Ser Val Pro Asn Ile Ser Gly Ala Thr Cys Ser Ala 
865                 870                 875                 880 


Phe Ala Ser Pro Phe Gly Cys Pro Tyr Ser His Arg His Ala Thr Tyr 
                885                 890                 895     


Pro Tyr Arg Val Cys Ser Val Asn Pro Pro Ser Ala Ile Glu Met Gln 
            900                 905                 910         


Leu Arg Arg Val Leu His Asp Ile Arg Asn Ser Leu Gln Asn Leu Ser 
        915                 920                 925             


Gln Tyr Pro Met Met Arg Gly Pro Asp Pro Ala Ala Ala Pro Tyr Ser 
    930                 935                 940                 


Thr Gln Lys Ser Ser Val Leu Pro Leu Tyr Glu Asn Thr Phe Gln Glu 
945                 950                 955                 960 


Leu Gln Val Met Arg Arg Ser Leu Asn Leu Phe Arg Thr Gln Met Met 
                965                 970                 975     


Asp Leu Glu Leu Ala Met Leu Arg Gln Gln Thr Met Val Tyr His His 
            980                 985                 990         


Met Thr Glu Glu Glu Arg Phe Glu  Val Asp Gln Leu Gln  Gly Leu Arg 
        995                 1000                 1005             


Asn Ser  Val Arg Met Glu Leu  Gln Asp Leu Glu Leu  Gln Leu Glu 
    1010                 1015                 1020             


Glu Arg  Leu Leu Gly Leu Glu  Glu Gln Leu Arg Ala  Val Arg Met 
    1025                 1030                 1035             


Pro Ser  Pro Phe Arg Ser Ser  Ala Leu Met Gly Met  Cys Gly Ser 
    1040                 1045                 1050             


Arg Ser  Ala Asp Asn Leu Ser  Cys Pro Ser Pro Leu  Asn Val Met 
    1055                 1060                 1065             


Glu Pro  Val Thr Glu Leu Met  Gln Glu Gln Ser Tyr  Leu Lys Ser 
    1070                 1075                 1080             


Glu Leu  Gly Leu Gly Leu Gly  Glu Met Gly Phe Glu  Ile Pro Pro 
    1085                 1090                 1095             


Gly Glu  Ser Ser Glu Ser Val  Phe Ser Gln Ala Thr  Ser Glu Ser 
    1100                 1105                 1110             


Ser Ser  Val Cys Ser Gly Pro  Ser His Ala Asn Arg  Arg Thr Gly 
    1115                 1120                 1125             


Val Pro  Ser Thr Ala Ser Val  Gly Lys Ser Lys Thr  Pro Leu Val 
    1130                 1135                 1140             


Ala Arg  Lys Lys Val Phe Arg  Ala Ser Val Ala Leu  Thr Pro Thr 
    1145                 1150                 1155             


Ala Pro  Ser Arg Thr Gly Ser  Val Gln Thr Pro Pro  Asp Leu Glu 
    1160                 1165                 1170             


Ser Ser  Glu Glu Val Asp Ala  Ala Glu Gly Ala Pro  Glu Val Val 
    1175                 1180                 1185             


Gly Pro  Lys Ser Glu Val Glu  Glu Gly His Gly Lys  Leu Pro Ser 
    1190                 1195                 1200             


Met Pro  Ala Ala Glu Glu Met  His Lys Asn Val Glu  Gln Asp Glu 
    1205                 1210                 1215             


Leu Gln  Gln Val Ile Arg Glu  Ile Lys Glu Ser Ile  Val Gly Glu 
    1220                 1225                 1230             


Ile Arg  Arg Glu Ile Val Ser  Gly Leu Leu Ala Ala  Val Ser Ser 
    1235                 1240                 1245             


Ser Lys  Ala Ser Asn Ser Lys  Gln Asp Tyr His 
    1250                 1255                 


<210>  1401
<211>  359
<212>  PRT
<213>  Human

<400>  1401

Met Gly Leu Leu Val Phe Val Arg Asn Leu Leu Leu Ala Leu Cys Leu 
1               5                   10                  15      


Phe Leu Val Leu Gly Phe Leu Tyr Tyr Ser Ala Trp Lys Leu His Leu 
            20                  25                  30          


Leu Gln Trp Glu Glu Asp Ser Lys Tyr Asp Arg Leu Gly Phe Leu Leu 
        35                  40                  45              


Asn Leu Asp Ser Lys Leu Pro Ala Glu Leu Ala Thr Lys Tyr Ala Asn 
    50                  55                  60                  


Phe Ser Glu Gly Ala Cys Lys Pro Gly Tyr Ala Ser Ala Leu Met Thr 
65                  70                  75                  80  


Ala Ile Phe Pro Arg Phe Ser Lys Pro Ala Pro Met Phe Leu Asp Asp 
                85                  90                  95      


Ser Phe Arg Lys Trp Ala Arg Ile Arg Glu Phe Val Pro Pro Phe Gly 
            100                 105                 110         


Ile Lys Gly Gln Asp Asn Leu Ile Lys Ala Ile Leu Ser Val Thr Lys 
        115                 120                 125             


Glu Tyr Arg Leu Thr Pro Ala Leu Asp Ser Leu Arg Cys Arg Arg Cys 
    130                 135                 140                 


Ile Ile Val Gly Asn Gly Gly Val Leu Ala Asn Lys Ser Leu Gly Ser 
145                 150                 155                 160 


Arg Ile Asp Asp Tyr Asp Ile Val Val Arg Leu Asn Ser Ala Pro Val 
                165                 170                 175     


Lys Gly Phe Glu Lys Asp Val Gly Ser Lys Thr Thr Leu Arg Ile Thr 
            180                 185                 190         


Tyr Pro Glu Gly Ala Met Gln Arg Pro Glu Gln Tyr Glu Arg Asp Ser 
        195                 200                 205             


Leu Phe Val Leu Ala Gly Phe Lys Trp Gln Asp Phe Lys Trp Leu Lys 
    210                 215                 220                 


Tyr Ile Val Tyr Lys Glu Arg Val Ser Ala Ser Asp Gly Phe Trp Lys 
225                 230                 235                 240 


Ser Val Ala Thr Arg Val Pro Lys Glu Pro Pro Glu Ile Arg Ile Leu 
                245                 250                 255     


Asn Pro Tyr Phe Ile Gln Glu Ala Ala Phe Thr Leu Ile Gly Leu Pro 
            260                 265                 270         


Phe Asn Asn Gly Leu Met Gly Arg Gly Asn Ile Pro Thr Leu Gly Ser 
        275                 280                 285             


Val Ala Val Thr Met Ala Leu His Gly Cys Asp Glu Val Ala Val Ala 
    290                 295                 300                 


Gly Phe Gly Tyr Asp Met Ser Thr Pro Asn Ala Pro Leu His Tyr Tyr 
305                 310                 315                 320 


Glu Thr Val Arg Met Ala Ala Ile Lys Glu Ser Trp Thr His Asn Ile 
                325                 330                 335     


Gln Arg Glu Lys Glu Phe Leu Arg Lys Leu Val Lys Ala Arg Val Ile 
            340                 345                 350         


Thr Asp Leu Ser Ser Gly Ile 
        355                 


<210>  1402
<211>  8749
<212>  PRT
<213>  Human

<400>  1402

Met Ala Thr Ser Arg Gly Ala Ser Arg Cys Pro Arg Asp Ile Ala Asn 
1               5                   10                  15      


Val Met Gln Arg Leu Gln Asp Glu Gln Glu Ile Val Gln Lys Arg Thr 
            20                  25                  30          


Phe Thr Lys Trp Ile Asn Ser His Leu Ala Lys Arg Lys Pro Pro Met 
        35                  40                  45              


Val Val Asp Asp Leu Phe Glu Asp Met Lys Asp Gly Val Lys Leu Leu 
    50                  55                  60                  


Ala Leu Leu Glu Val Leu Ser Gly Gln Lys Leu Pro Cys Glu Gln Gly 
65                  70                  75                  80  


Arg Arg Met Lys Arg Ile His Ala Val Ala Asn Ile Gly Thr Ala Leu 
                85                  90                  95      


Lys Phe Leu Glu Gly Arg Lys Ser Met His Arg Gly Ser Pro Ile Lys 
            100                 105                 110         


Leu Val Asn Ile Asn Ser Thr Asp Ile Ala Asp Gly Arg Pro Ser Ile 
        115                 120                 125             


Val Leu Gly Leu Met Trp Thr Ile Ile Leu Tyr Phe Gln Ile Glu Glu 
    130                 135                 140                 


Leu Thr Ser Asn Leu Pro Gln Leu Gln Ser Leu Ser Ser Ser Ala Ser 
145                 150                 155                 160 


Ser Val Asp Ser Ile Val Ser Ser Glu Thr Pro Ser Pro Pro Ser Lys 
                165                 170                 175     


Arg Lys Val Thr Thr Lys Ile Gln Gly Asn Ala Lys Lys Ala Leu Leu 
            180                 185                 190         


Lys Trp Val Gln Tyr Thr Ala Gly Lys Gln Thr Gly Ile Glu Val Lys 
        195                 200                 205             


Asp Phe Gly Lys Ser Trp Arg Ser Gly Val Ala Phe His Ser Val Ile 
    210                 215                 220                 


His Ala Ile Arg Pro Glu Leu Val Asp Leu Glu Thr Val Lys Gly Arg 
225                 230                 235                 240 


Ser Asn Arg Glu Asn Leu Glu Asp Ala Phe Thr Ile Ala Glu Thr Glu 
                245                 250                 255     


Leu Gly Ile Pro Arg Leu Leu Asp Pro Glu Asp Val Asp Val Asp Lys 
            260                 265                 270         


Pro Asp Glu Lys Ser Ile Met Thr Tyr Val Ala Gln Phe Leu Lys His 
        275                 280                 285             


Tyr Pro Asp Ile His Asn Ala Ser Thr Asp Gly Gln Glu Asp Asp Glu 
    290                 295                 300                 


Ile Leu Pro Gly Phe Pro Ser Phe Ala Asn Ser Val Gln Asn Phe Lys 
305                 310                 315                 320 


Arg Glu Asp Arg Val Ile Phe Lys Glu Met Lys Val Trp Ile Glu Gln 
                325                 330                 335     


Phe Glu Arg Asp Leu Thr Arg Ala Gln Met Val Glu Ser Asn Leu Gln 
            340                 345                 350         


Asp Lys Tyr Gln Ser Phe Lys His Phe Arg Val Gln Tyr Glu Met Lys 
        355                 360                 365             


Arg Lys Gln Ile Glu His Leu Ile Gln Pro Leu His Arg Asp Gly Lys 
    370                 375                 380                 


Leu Ser Leu Asp Gln Ala Leu Val Lys Gln Ser Trp Asp Arg Val Thr 
385                 390                 395                 400 


Ser Arg Leu Phe Asp Trp His Ile Gln Leu Asp Lys Ser Leu Pro Ala 
                405                 410                 415     


Pro Leu Gly Thr Ile Gly Ala Trp Leu Tyr Arg Ala Glu Val Ala Leu 
            420                 425                 430         


Arg Glu Glu Ile Thr Val Gln Gln Val His Glu Glu Thr Ala Asn Thr 
        435                 440                 445             


Ile Gln Arg Lys Leu Glu Gln His Lys Asp Leu Leu Gln Asn Thr Asp 
    450                 455                 460                 


Ala His Lys Arg Ala Phe His Glu Ile Tyr Arg Thr Arg Ser Val Asn 
465                 470                 475                 480 


Gly Ile Pro Val Pro Pro Asp Gln Leu Glu Asp Met Ala Glu Arg Phe 
                485                 490                 495     


His Phe Val Ser Ser Thr Ser Glu Leu His Leu Met Lys Met Glu Phe 
            500                 505                 510         


Leu Glu Leu Lys Tyr Arg Leu Leu Ser Leu Leu Val Leu Ala Glu Ser 
        515                 520                 525             


Lys Leu Lys Ser Trp Ile Ile Lys Tyr Gly Arg Arg Glu Ser Val Glu 
    530                 535                 540                 


Gln Leu Leu Gln Asn Tyr Val Ser Phe Ile Glu Asn Ser Lys Phe Phe 
545                 550                 555                 560 


Glu Gln Tyr Glu Val Thr Tyr Gln Ile Leu Lys Gln Thr Ala Glu Met 
                565                 570                 575     


Tyr Val Lys Ala Asp Gly Ser Val Glu Glu Ala Glu Asn Val Met Lys 
            580                 585                 590         


Phe Met Asn Glu Thr Thr Ala Gln Trp Arg Asn Leu Ser Val Glu Val 
        595                 600                 605             


Arg Ser Val Arg Ser Met Leu Glu Glu Val Ile Ser Asn Trp Asp Arg 
    610                 615                 620                 


Tyr Gly Asn Thr Val Ala Ser Leu Gln Ala Trp Leu Glu Asp Ala Glu 
625                 630                 635                 640 


Lys Met Leu Asn Gln Ser Glu Asn Ala Lys Lys Asp Phe Phe Arg Asn 
                645                 650                 655     


Leu Pro His Trp Ile Gln Gln His Thr Ala Met Asn Asp Ala Gly Asn 
            660                 665                 670         


Phe Leu Ile Glu Thr Cys Asp Glu Met Val Ser Arg Asp Leu Lys Gln 
        675                 680                 685             


Gln Leu Leu Leu Leu Asn Gly Arg Trp Arg Glu Leu Phe Met Glu Val 
    690                 695                 700                 


Lys Gln Tyr Ala Gln Ala Asp Glu Met Asp Arg Met Lys Lys Glu Tyr 
705                 710                 715                 720 


Thr Asp Cys Val Val Thr Leu Ser Ala Phe Ala Thr Glu Ala His Lys 
                725                 730                 735     


Lys Leu Ser Glu Pro Leu Glu Val Ser Phe Met Asn Val Lys Leu Leu 
            740                 745                 750         


Ile Gln Asp Leu Glu Asp Ile Glu Gln Arg Val Pro Val Met Asp Ala 
        755                 760                 765             


Gln Tyr Lys Ile Ile Thr Lys Thr Ala His Leu Ile Thr Lys Glu Ser 
    770                 775                 780                 


Pro Gln Glu Glu Gly Lys Glu Met Phe Ala Thr Met Ser Lys Leu Lys 
785                 790                 795                 800 


Glu Gln Leu Thr Lys Val Lys Glu Cys Tyr Ser Pro Leu Leu Tyr Glu 
                805                 810                 815     


Ser Gln Gln Leu Leu Ile Pro Leu Glu Glu Leu Glu Lys Gln Met Thr 
            820                 825                 830         


Ser Phe Tyr Asp Ser Leu Gly Lys Ile Asn Glu Ile Ile Thr Val Leu 
        835                 840                 845             


Glu Arg Glu Ala Gln Ser Ser Ala Leu Phe Lys Gln Lys His Gln Glu 
    850                 855                 860                 


Leu Leu Ala Cys Gln Glu Asn Cys Lys Lys Thr Leu Thr Leu Ile Glu 
865                 870                 875                 880 


Lys Gly Ser Gln Ser Val Gln Lys Phe Val Thr Leu Ser Asn Val Leu 
                885                 890                 895     


Lys His Phe Asp Gln Thr Arg Leu Gln Arg Gln Ile Ala Asp Ile His 
            900                 905                 910         


Val Ala Phe Gln Ser Met Val Lys Lys Thr Gly Asp Trp Lys Lys His 
        915                 920                 925             


Val Glu Thr Asn Ser Arg Leu Met Lys Lys Phe Glu Glu Ser Arg Ala 
    930                 935                 940                 


Glu Leu Glu Lys Val Leu Arg Ile Ala Gln Glu Gly Leu Glu Glu Lys 
945                 950                 955                 960 


Gly Asp Pro Glu Glu Leu Leu Arg Arg His Thr Glu Phe Phe Ser Gln 
                965                 970                 975     


Leu Asp Gln Arg Val Leu Asn Ala Phe Leu Lys Ala Cys Asp Glu Leu 
            980                 985                 990         


Thr Asp Ile Leu Pro Glu Gln Glu  Gln Gln Gly Leu Gln  Glu Ala Val 
        995                 1000                 1005             


Arg Lys  Leu His Lys Gln Trp  Lys Asp Leu Gln Gly  Glu Ala Pro 
    1010                 1015                 1020             


Tyr His  Leu Leu His Leu Lys  Ile Asp Val Glu Lys  Asn Arg Phe 
    1025                 1030                 1035             


Leu Ala  Ser Val Glu Glu Cys  Arg Thr Glu Leu Asp  Arg Glu Thr 
    1040                 1045                 1050             


Lys Leu  Met Pro Gln Glu Gly  Ser Glu Lys Ile Ile  Lys Glu His 
    1055                 1060                 1065             


Arg Val  Phe Phe Ser Asp Lys  Gly Pro His His Leu  Cys Glu Lys 
    1070                 1075                 1080             


Arg Leu  Gln Leu Ile Glu Glu  Leu Cys Val Lys Leu  Pro Val Arg 
    1085                 1090                 1095             


Asp Pro  Val Arg Asp Thr Pro  Gly Thr Cys His Val  Thr Leu Lys 
    1100                 1105                 1110             


Glu Leu  Arg Ala Ala Ile Asp  Ser Thr Tyr Arg Lys  Leu Met Glu 
    1115                 1120                 1125             


Asp Pro  Asp Lys Trp Lys Asp  Tyr Thr Ser Arg Phe  Ser Glu Phe 
    1130                 1135                 1140             


Ser Ser  Trp Ile Ser Thr Asn  Glu Thr Gln Leu Lys  Gly Ile Lys 
    1145                 1150                 1155             


Gly Glu  Ala Ile Asp Thr Ala  Asn His Gly Glu Val  Lys Arg Ala 
    1160                 1165                 1170             


Val Glu  Glu Ile Arg Asn Gly  Val Thr Lys Arg Gly  Glu Thr Leu 
    1175                 1180                 1185             


Ser Trp  Leu Lys Ser Arg Leu  Lys Val Leu Thr Glu  Val Ser Ser 
    1190                 1195                 1200             


Glu Asn  Glu Ala Gln Lys Gln  Gly Asp Glu Leu Ala  Lys Leu Ser 
    1205                 1210                 1215             


Ser Ser  Phe Lys Ala Leu Val  Thr Leu Leu Ser Glu  Val Glu Lys 
    1220                 1225                 1230             


Met Leu  Ser Asn Phe Gly Asp  Cys Val Gln Tyr Lys  Glu Ile Val 
    1235                 1240                 1245             


Lys Asn  Ser Leu Glu Glu Leu  Ile Ser Gly Ser Lys  Glu Val Gln 
    1250                 1255                 1260             


Glu Gln  Ala Glu Lys Ile Leu  Asp Thr Glu Asn Leu  Phe Glu Ala 
    1265                 1270                 1275             


Gln Gln  Leu Leu Leu His His  Gln Gln Lys Thr Lys  Arg Ile Ser 
    1280                 1285                 1290             


Ala Lys  Lys Arg Asp Val Gln  Gln Gln Ile Ala Gln  Ala Gln Gln 
    1295                 1300                 1305             


Gly Glu  Gly Gly Leu Pro Asp  Arg Gly His Glu Glu  Leu Arg Lys 
    1310                 1315                 1320             


Leu Glu  Ser Thr Leu Asp Gly  Leu Glu Arg Ser Arg  Glu Arg Gln 
    1325                 1330                 1335             


Glu Arg  Arg Ile Gln Val Thr  Leu Arg Lys Trp Glu  Arg Phe Glu 
    1340                 1345                 1350             


Thr Asn  Lys Glu Thr Val Val  Arg Tyr Leu Phe Gln  Thr Gly Ser 
    1355                 1360                 1365             


Ser His  Glu Arg Phe Leu Ser  Phe Ser Ser Leu Glu  Ser Leu Ser 
    1370                 1375                 1380             


Ser Glu  Leu Glu Gln Thr Lys  Glu Phe Ser Lys Arg  Thr Glu Ser 
    1385                 1390                 1395             


Ile Ala  Val Gln Ala Glu Asn  Leu Val Lys Glu Ala  Ser Glu Ile 
    1400                 1405                 1410             


Pro Leu  Gly Pro Gln Asn Lys  Gln Leu Leu Gln Gln  Gln Ala Lys 
    1415                 1420                 1425             


Ser Ile  Lys Glu Gln Val Lys  Lys Leu Glu Asp Thr  Leu Glu Glu 
    1430                 1435                 1440             


Asp Ile  Lys Thr Met Glu Met  Val Lys Thr Lys Trp  Asp His Phe 
    1445                 1450                 1455             


Gly Ser  Asn Phe Glu Thr Leu  Ser Val Trp Ile Thr  Glu Lys Glu 
    1460                 1465                 1470             


Lys Glu  Leu Asn Ala Leu Glu  Thr Ser Ser Ser Ala  Met Asp Met 
    1475                 1480                 1485             


Gln Ile  Ser Gln Ile Lys Val  Thr Ile Gln Glu Ile  Glu Ser Lys 
    1490                 1495                 1500             


Leu Ser  Ser Ile Val Gly Leu  Glu Glu Glu Ala Gln  Ser Phe Ala 
    1505                 1510                 1515             


Gln Phe  Val Thr Thr Gly Glu  Ser Ala Arg Ile Lys  Ala Lys Leu 
    1520                 1525                 1530             


Thr Gln  Ile Arg Arg Tyr Gly  Glu Glu Leu Arg Glu  His Ala Gln 
    1535                 1540                 1545             


Cys Leu  Glu Gly Thr Ile Leu  Gly His Leu Ser Gln  Gln Gln Lys 
    1550                 1555                 1560             


Phe Glu  Glu Asn Leu Arg Lys  Ile Gln Gln Ser Val  Ser Glu Phe 
    1565                 1570                 1575             


Glu Asp  Lys Leu Ala Val Pro  Ile Lys Ile Cys Ser  Ser Ala Thr 
    1580                 1585                 1590             


Glu Thr  Tyr Lys Val Leu Gln  Glu His Met Asp Leu  Cys Gln Ala 
    1595                 1600                 1605             


Leu Glu  Ser Leu Ser Ser Ala  Ile Thr Ala Phe Ser  Ala Ser Ala 
    1610                 1615                 1620             


Arg Lys  Val Val Asn Arg Asp  Ser Cys Val Gln Glu  Ala Ala Ala 
    1625                 1630                 1635             


Leu Gln  Gln Gln Tyr Glu Asp  Ile Leu Arg Arg Ala  Lys Glu Arg 
    1640                 1645                 1650             


Gln Thr  Ala Leu Glu Asn Leu  Leu Ala His Trp Gln  Arg Leu Glu 
    1655                 1660                 1665             


Lys Glu  Leu Ser Ser Phe Leu  Thr Trp Leu Glu Arg  Gly Glu Ala 
    1670                 1675                 1680             


Lys Ala  Ser Ser Pro Glu Met  Asp Ile Ser Ala Asp  Arg Val Lys 
    1685                 1690                 1695             


Val Glu  Gly Glu Leu Gln Leu  Ile Gln Ala Leu Gln  Asn Glu Val 
    1700                 1705                 1710             


Val Ser  Gln Ala Ser Phe Tyr  Ser Lys Leu Leu Gln  Leu Lys Glu 
    1715                 1720                 1725             


Ser Leu  Phe Ser Val Ala Ser  Lys Asp Asp Val Lys  Met Met Lys 
    1730                 1735                 1740             


Leu His  Leu Glu Gln Leu Asp  Glu Arg Trp Arg Asp  Leu Pro Gln 
    1745                 1750                 1755             


Ile Ile  Asn Lys Arg Ile Asn  Phe Leu Gln Ser Val  Val Ala Glu 
    1760                 1765                 1770             


His Gln  Gln Phe Asp Glu Leu  Leu Leu Ser Phe Ser  Val Trp Ile 
    1775                 1780                 1785             


Lys Leu  Phe Leu Ser Glu Leu  Gln Thr Thr Ser Glu  Ile Ser Ile 
    1790                 1795                 1800             


Met Asp  His Gln Val Ala Leu  Thr Arg His Lys Asp  His Ala Ala 
    1805                 1810                 1815             


Glu Val  Glu Ser Lys Lys Gly  Glu Leu Gln Ser Leu  Gln Gly His 
    1820                 1825                 1830             


Leu Ala  Lys Leu Gly Ser Leu  Gly Arg Ala Glu Asp  Leu His Leu 
    1835                 1840                 1845             


Leu Gln  Gly Lys Ala Glu Asp  Cys Phe Gln Leu Phe  Glu Glu Ala 
    1850                 1855                 1860             


Ser Gln  Val Val Glu Arg Arg  Gln Leu Ala Leu Ser  His Leu Ala 
    1865                 1870                 1875             


Glu Phe  Leu Gln Ser His Ala  Ser Leu Ser Gly Ile  Leu Arg Gln 
    1880                 1885                 1890             


Leu Arg  Gln Thr Val Glu Ala  Thr Asn Ser Met Asn  Lys Asn Glu 
    1895                 1900                 1905             


Ser Asp  Leu Ile Glu Lys Asp  Leu Asn Asp Ala Leu  Gln Asn Ala 
    1910                 1915                 1920             


Lys Ala  Leu Glu Ser Ala Ala  Val Ser Leu Asp Gly  Ile Leu Ser 
    1925                 1930                 1935             


Lys Ala  Gln Tyr His Leu Lys  Ile Gly Ser Ser Glu  Gln Arg Thr 
    1940                 1945                 1950             


Ser Cys  Arg Ala Thr Ala Asp  Gln Leu Cys Gly Glu  Val Glu Arg 
    1955                 1960                 1965             


Ile Gln  Asn Leu Leu Gly Thr  Lys Gln Ser Glu Ala  Asp Ala Leu 
    1970                 1975                 1980             


Ala Val  Leu Lys Lys Ala Phe  Gln Asp Gln Lys Glu  Glu Leu Leu 
    1985                 1990                 1995             


Lys Ser  Ile Glu Asp Ile Glu  Glu Arg Thr Asp Lys  Glu Arg Leu 
    2000                 2005                 2010             


Lys Glu  Pro Thr Arg Gln Ala  Leu Gln Gln Arg Leu  Arg Val Phe 
    2015                 2020                 2025             


Asn Gln  Leu Glu Asp Glu Leu  Asn Ser His Glu His  Glu Leu Cys 
    2030                 2035                 2040             


Trp Leu  Lys Asp Lys Ala Lys  Gln Ile Ala Gln Lys  Asp Val Ala 
    2045                 2050                 2055             


Phe Ala  Pro Glu Val Asp Arg  Glu Ile Asn Arg Leu  Glu Val Thr 
    2060                 2065                 2070             


Trp Asp  Asp Thr Lys Arg Leu  Ile His Glu Asn Gln  Gly Gln Cys 
    2075                 2080                 2085             


Cys Gly  Leu Ile Asp Leu Met  Arg Glu Tyr Gln Asn  Leu Lys Ser 
    2090                 2095                 2100             


Ala Val  Ser Lys Val Leu Glu  Asn Ala Ser Ser Val  Ile Val Thr 
    2105                 2110                 2115             


Arg Thr  Thr Ile Lys Asp Gln  Glu Asp Leu Lys Trp  Ala Phe Ser 
    2120                 2125                 2130             


Lys His  Glu Thr Ala Lys Asn  Lys Met Asn Tyr Lys  Gln Lys Asp 
    2135                 2140                 2145             


Leu Asp  Asn Phe Thr Ser Lys  Gly Lys His Leu Leu  Ser Glu Leu 
    2150                 2155                 2160             


Lys Lys  Ile His Ser Ser Asp  Phe Ser Leu Val Lys  Thr Asp Met 
    2165                 2170                 2175             


Glu Ser  Thr Val Asp Lys Trp  Leu Asp Val Ser Glu  Lys Leu Glu 
    2180                 2185                 2190             


Glu Asn  Met Asp Arg Leu Arg  Val Ser Leu Ser Ile  Trp Asp Asp 
    2195                 2200                 2205             


Val Leu  Ser Thr Arg Asp Glu  Ile Glu Gly Trp Ser  Asn Asn Cys 
    2210                 2215                 2220             


Val Pro  Gln Met Ala Glu Asn  Ile Ser Asn Leu Asp  Asn His Leu 
    2225                 2230                 2235             


Arg Ala  Glu Glu Leu Leu Lys  Glu Phe Glu Ser Glu  Val Lys Asn 
    2240                 2245                 2250             


Lys Ala  Leu Arg Leu Glu Glu  Leu His Ser Lys Val  Asn Asp Leu 
    2255                 2260                 2265             


Lys Glu  Leu Thr Lys Asn Leu  Glu Thr Pro Pro Asp  Leu Gln Phe 
    2270                 2275                 2280             


Ile Glu  Ala Asp Leu Met Gln  Lys Leu Glu His Ala  Lys Glu Ile 
    2285                 2290                 2295             


Thr Glu  Val Ala Lys Gly Thr  Leu Lys Asp Phe Thr  Ala Gln Ser 
    2300                 2305                 2310             


Thr Gln  Val Glu Lys Phe Ile  Asn Asp Ile Thr Thr  Trp Phe Thr 
    2315                 2320                 2325             


Lys Val  Glu Glu Ser Leu Met  Asn Cys Ala Gln Asn  Glu Thr Cys 
    2330                 2335                 2340             


Glu Ala  Leu Lys Lys Val Lys  Asp Ile Gln Lys Glu  Leu Gln Ser 
    2345                 2350                 2355             


Gln Gln  Ser Asn Ile Ser Ser  Thr Gln Glu Asn Leu  Asn Ser Leu 
    2360                 2365                 2370             


Cys Arg  Lys Tyr His Ser Ala  Glu Leu Glu Ser Leu  Gly Arg Ala 
    2375                 2380                 2385             


Met Thr  Gly Leu Ile Lys Lys  His Glu Ala Val Ser  Gln Leu Cys 
    2390                 2395                 2400             


Ser Lys  Thr Gln Ala Ser Leu  Gln Glu Ser Leu Glu  Lys His Phe 
    2405                 2410                 2415             


Ser Glu  Ser Met Gln Glu Phe  Gln Glu Trp Phe Leu  Gly Ala Lys 
    2420                 2425                 2430             


Ala Ala  Ala Lys Glu Ser Ser  Asp Arg Thr Gly Asp  Ser Lys Val 
    2435                 2440                 2445             


Leu Glu  Ala Lys Leu His Asp  Leu Gln Asn Ile Leu  Asp Ser Val 
    2450                 2455                 2460             


Ser Asp  Gly Gln Ser Lys Leu  Asp Ala Val Thr Gln  Glu Gly Gln 
    2465                 2470                 2475             


Thr Leu  Tyr Ala His Leu Ser  Lys Gln Ile Val Ser  Ser Ile Gln 
    2480                 2485                 2490             


Glu Gln  Ile Thr Lys Ala Asn  Glu Glu Phe Gln Ala  Phe Leu Lys 
    2495                 2500                 2505             


Gln Cys  Leu Lys Asp Lys Gln  Ala Leu Gln Asp Cys  Ala Ser Glu 
    2510                 2515                 2520             


Leu Gly  Ser Phe Glu Asp Gln  His Arg Lys Leu Asn  Leu Trp Ile 
    2525                 2530                 2535             


His Glu  Met Glu Glu Arg Phe  Asn Thr Glu Asn Leu  Gly Glu Ser 
    2540                 2545                 2550             


Lys Gln  His Ile Pro Glu Lys  Lys Asn Glu Val His  Lys Val Glu 
    2555                 2560                 2565             


Met Phe  Leu Gly Glu Leu Leu  Ala Ala Arg Glu Ser  Leu Asp Lys 
    2570                 2575                 2580             


Leu Ser  Gln Arg Gly Gln Leu  Leu Ser Glu Glu Gly  His Gly Ala 
    2585                 2590                 2595             


Gly Gln  Glu Gly Arg Leu Cys  Ser Gln Leu Leu Thr  Ser His Gln 
    2600                 2605                 2610             


Asn Leu  Leu Arg Met Thr Lys  Glu Lys Leu Arg Ser  Cys Gln Val 
    2615                 2620                 2625             


Ala Leu  Gln Glu His Glu Ala  Leu Glu Glu Ala Leu  Gln Ser Met 
    2630                 2635                 2640             


Trp Phe  Trp Val Lys Ala Ile  Gln Asp Arg Leu Ala  Cys Ala Glu 
    2645                 2650                 2655             


Ser Thr  Leu Gly Ser Lys Asp  Thr Leu Glu Lys Arg  Leu Ser Gln 
    2660                 2665                 2670             


Ile Gln  Asp Ile Leu Leu Met  Lys Gly Glu Gly Glu  Val Lys Leu 
    2675                 2680                 2685             


Asn Met  Ala Ile Gly Lys Gly  Glu Gln Ala Leu Arg  Ser Ser Asn 
    2690                 2695                 2700             


Lys Glu  Gly Gln Arg Val Ile  Gln Thr Gln Leu Glu  Thr Leu Lys 
    2705                 2710                 2715             


Glu Val  Trp Ala Asp Ile Met  Ser Ser Ser Val His  Ala Gln Ser 
    2720                 2725                 2730             


Thr Leu  Glu Ser Val Ile Ser  Gln Trp Asn Asp Tyr  Val Glu Arg 
    2735                 2740                 2745             


Lys Asn  Gln Leu Glu Gln Trp  Met Glu Ser Val Asp  Gln Lys Ile 
    2750                 2755                 2760             


Glu His  Pro Leu Gln Pro Gln  Pro Gly Leu Lys Glu  Lys Phe Val 
    2765                 2770                 2775             


Leu Leu  Asp His Leu Gln Ser  Ile Leu Ser Glu Ala  Glu Asp His 
    2780                 2785                 2790             


Thr Arg  Ala Leu His Arg Leu  Ile Ala Lys Ser Arg  Glu Leu Tyr 
    2795                 2800                 2805             


Glu Lys  Thr Glu Asp Glu Ser  Phe Lys Asp Thr Ala  Gln Glu Glu 
    2810                 2815                 2820             


Leu Lys  Thr Gln Phe Asn Asp  Ile Met Thr Val Ala  Lys Glu Lys 
    2825                 2830                 2835             


Met Arg  Lys Val Glu Glu Ile  Val Lys Asp His Leu  Met Tyr Leu 
    2840                 2845                 2850             


Asp Ala  Val His Glu Phe Thr  Asp Trp Leu His Ser  Ala Lys Glu 
    2855                 2860                 2865             


Glu Leu  His Arg Trp Ser Asp  Met Ser Gly Asp Ser  Ser Ala Thr 
    2870                 2875                 2880             


Gln Lys  Lys Leu Ser Lys Ile  Lys Glu Leu Ile Asp  Ser Arg Glu 
    2885                 2890                 2895             


Ile Gly  Ala Ser Arg Leu Ser  Arg Val Glu Ser Leu  Ala Pro Glu 
    2900                 2905                 2910             


Val Lys  Gln Asn Thr Thr Ala  Ser Gly Cys Glu Leu  Met His Thr 
    2915                 2920                 2925             


Glu Met  Gln Ala Leu Arg Ala  Asp Trp Lys Gln Trp  Glu Asp Ser 
    2930                 2935                 2940             


Val Phe  Gln Thr Gln Ser Cys  Leu Glu Asn Leu Val  Ser Gln Met 
    2945                 2950                 2955             


Ala Leu  Ser Glu Gln Glu Phe  Ser Gly Gln Val Ala  Gln Leu Glu 
    2960                 2965                 2970             


Gln Ala  Leu Glu Gln Phe Ser  Ala Leu Leu Lys Thr  Trp Ala Gln 
    2975                 2980                 2985             


Gln Leu  Thr Leu Leu Glu Gly  Lys Asn Thr Asp Glu  Glu Ile Val 
    2990                 2995                 3000             


Glu Cys  Trp His Lys Gly Gln  Glu Ile Leu Asp Ala  Leu Gln Lys 
    3005                 3010                 3015             


Ala Glu  Pro Arg Thr Glu Asp  Leu Lys Ser Gln Leu  Asn Glu Leu 
    3020                 3025                 3030             


Cys Arg  Phe Ser Arg Asp Leu  Ser Thr Tyr Ser Gly  Lys Val Ser 
    3035                 3040                 3045             


Gly Leu  Ile Lys Glu Tyr Asn  Cys Leu Cys Leu Gln  Ala Ser Lys 
    3050                 3055                 3060             


Gly Cys  Gln Asn Lys Glu Gln  Ile Leu Gln Gln Arg  Phe Arg Lys 
    3065                 3070                 3075             


Ala Phe  Arg Asp Phe Gln Gln  Trp Leu Val Asn Ala  Lys Ile Thr 
    3080                 3085                 3090             


Thr Ala  Lys Cys Phe Asp Ile  Pro Gln Asn Ile Ser  Glu Val Ser 
    3095                 3100                 3105             


Thr Ser  Leu Gln Lys Ile Gln  Glu Phe Leu Ser Glu  Ser Glu Asn 
    3110                 3115                 3120             


Gly Gln  His Lys Leu Asn Met  Met Leu Ser Lys Gly  Glu Leu Leu 
    3125                 3130                 3135             


Ser Thr  Leu Leu Thr Lys Glu  Lys Ala Lys Gly Ile  Gln Ala Lys 
    3140                 3145                 3150             


Val Thr  Ala Ala Lys Glu Asp  Trp Lys Asn Phe His  Ser Asn Leu 
    3155                 3160                 3165             


His Gln  Lys Glu Ser Ala Leu  Glu Asn Leu Lys Ile  Gln Met Lys 
    3170                 3175                 3180             


Asp Phe  Glu Val Ser Ala Glu  Pro Ile Gln Asp Trp  Leu Ser Lys 
    3185                 3190                 3195             


Thr Glu  Lys Met Val His Glu  Ser Ser Asn Arg Leu  Tyr Asp Leu 
    3200                 3205                 3210             


Pro Ala  Lys Arg Arg Glu Gln  Gln Lys Leu Gln Ser  Val Leu Glu 
    3215                 3220                 3225             


Glu Ile  His Cys Tyr Glu Pro  Gln Leu Asn Arg Leu  Lys Glu Lys 
    3230                 3235                 3240             


Ala Gln  Gln Leu Trp Glu Gly  Gln Ala Ala Ser Lys  Ser Phe Arg 
    3245                 3250                 3255             


His Arg  Val Ser Gln Leu Ser  Ser Gln Tyr Leu Ala  Leu Ser Asn 
    3260                 3265                 3270             


Leu Thr  Lys Glu Lys Val Ser  Arg Leu Asp Arg Ile  Val Ala Glu 
    3275                 3280                 3285             


His Asn  Gln Phe Ser Leu Gly  Ile Lys Glu Leu Gln  Asp Trp Met 
    3290                 3295                 3300             


Thr Asp  Ala Ile His Met Leu  Asp Ser Tyr Cys His  Pro Thr Ser 
    3305                 3310                 3315             


Asp Lys  Ser Val Leu Asp Ser  Arg Thr Leu Lys Leu  Glu Ala Leu 
    3320                 3325                 3330             


Leu Ser  Val Lys Gln Glu Lys  Glu Ile Gln Met Lys  Met Ile Val 
    3335                 3340                 3345             


Thr Arg  Gly Glu Ser Val Leu  Gln Asn Thr Ser Pro  Glu Gly Ile 
    3350                 3355                 3360             


Pro Thr  Ile Gln Gln Gln Leu  Gln Ser Val Lys Asp  Met Trp Ala 
    3365                 3370                 3375             


Ser Leu  Leu Ser Ala Gly Ile  Arg Cys Lys Ser Gln  Leu Glu Gly 
    3380                 3385                 3390             


Ala Leu  Ser Lys Trp Thr Ser  Tyr Gln Asp Gly Val  Arg Gln Phe 
    3395                 3400                 3405             


Ser Gly  Trp Met Asp Ser Met  Glu Ala Asn Leu Asn  Glu Ser Glu 
    3410                 3415                 3420             


Arg Gln  His Ala Glu Leu Arg  Asp Lys Thr Thr Met  Leu Gly Lys 
    3425                 3430                 3435             


Ala Lys  Leu Leu Asn Glu Glu  Val Leu Ser Tyr Ser  Ser Leu Leu 
    3440                 3445                 3450             


Glu Thr  Ile Glu Val Lys Gly  Ala Gly Met Thr Glu  His Tyr Val 
    3455                 3460                 3465             


Thr Gln  Leu Glu Leu Gln Asp  Leu Gln Glu Arg Tyr  Arg Ala Ile 
    3470                 3475                 3480             


Gln Glu  Arg Ala Lys Glu Ala  Val Thr Lys Ser Glu  Lys Leu Val 
    3485                 3490                 3495             


Arg Leu  His Gln Glu Tyr Gln  Arg Asp Leu Lys Ala  Phe Glu Val 
    3500                 3505                 3510             


Trp Leu  Gly Gln Glu Gln Glu  Lys Leu Asp Gln Tyr  Ser Val Leu 
    3515                 3520                 3525             


Glu Gly  Asp Ala His Thr His  Glu Thr Thr Leu Arg  Asp Leu Gln 
    3530                 3535                 3540             


Glu Leu  Gln Val His Cys Ala  Glu Gly Gln Ala Leu  Leu Asn Ser 
    3545                 3550                 3555             


Val Leu  His Thr Arg Glu Asp  Val Ile Pro Ser Gly  Ile Pro Gln 
    3560                 3565                 3570             


Ala Glu  Asp Arg Ala Leu Glu  Ser Leu Arg Gln Asp  Trp Gln Ala 
    3575                 3580                 3585             


Tyr Gln  His Arg Leu Ser Glu  Thr Arg Thr Gln Phe  Asn Asn Val 
    3590                 3595                 3600             


Val Asn  Lys Leu Arg Leu Met  Glu Gln Lys Phe Gln  Gln Val Asp 
    3605                 3610                 3615             


Glu Trp  Leu Lys Thr Ala Glu  Glu Lys Lys Trp His  Glu Glu Val 
    3620                 3625                 3630             


Thr Ala  Tyr Arg Asp Glu Val  Glu Glu Val Gly Ala  Arg Ala Gln 
    3635                 3640                 3645             


Glu Ile  Leu Asp Glu Ser His  Val Asn Ser Arg Met  Gly Cys Gln 
    3650                 3655                 3660             


Ala Thr  Gln Leu Thr Ser Arg  Tyr Gln Ala Leu Leu  Leu Gln Val 
    3665                 3670                 3675             


Leu Glu  Gln Ile Lys Phe Leu  Glu Glu Glu Ile Gln  Ser Leu Glu 
    3680                 3685                 3690             


Glu Ser  Glu Ser Ser Leu Ser  Ser Tyr Ser Asp Trp  Tyr Gly Ser 
    3695                 3700                 3705             


Thr His  Lys Asn Phe Lys Asn  Val Ala Thr Lys Ile  Asp Lys Val 
    3710                 3715                 3720             


Asp Thr  Val Met Met Gly Lys  Lys Leu Lys Thr Leu  Glu Val Leu 
    3725                 3730                 3735             


Leu Lys  Asp Met Glu Lys Gly  His Ser Leu Leu Lys  Ser Ala Arg 
    3740                 3745                 3750             


Glu Lys  Gly Glu Arg Ala Val  Lys Tyr Leu Glu Glu  Gly Glu Ala 
    3755                 3760                 3765             


Glu Arg  Leu Arg Lys Glu Ile  His Asp His Met Glu  Gln Leu Lys 
    3770                 3775                 3780             


Glu Leu  Thr Ser Thr Val Arg  Lys Glu His Met Thr  Leu Glu Lys 
    3785                 3790                 3795             


Gly Leu  His Leu Ala Lys Glu  Phe Ser Asp Lys Cys  Lys Ala Leu 
    3800                 3805                 3810             


Thr Gln  Trp Ile Ala Glu Tyr  Gln Glu Ile Leu His  Val Pro Glu 
    3815                 3820                 3825             


Glu Pro  Lys Met Glu Leu Tyr  Glu Lys Lys Ala Gln  Leu Ser Lys 
    3830                 3835                 3840             


Tyr Lys  Ser Leu Gln Gln Thr  Val Leu Ser His Glu  Pro Ser Val 
    3845                 3850                 3855             


Lys Ser  Val Arg Glu Lys Gly  Glu Ala Leu Leu Glu  Leu Val Gln 
    3860                 3865                 3870             


Asp Val  Thr Leu Lys Asp Lys  Ile Asp Gln Leu Gln  Ser Asp Tyr 
    3875                 3880                 3885             


Gln Asp  Leu Cys Ser Ile Gly  Lys Ala Met Met Glu  Glu Ile Ala 
    3890                 3895                 3900             


Gly Phe  Glu Asp Arg Leu Asn  Asn Leu Gln Met Lys  Gly Asp Thr 
    3905                 3910                 3915             


Leu Ile  Gly Gln Cys Ala Asp  His Leu Gln Ala Lys  Leu Lys Gln 
    3920                 3925                 3930             


Asn Val  His Ala His Leu Gln  Gly Thr Lys Asp Ser  Tyr Ser Ala 
    3935                 3940                 3945             


Ile Cys  Ser Thr Ala Gln Arg  Met Tyr Gln Ser Leu  Glu His Glu 
    3950                 3955                 3960             


Leu Gln  Lys His Val Ser Arg  Gln Asp Thr Leu Gln  Gln Cys Gln 
    3965                 3970                 3975             


Ala Trp  Leu Ser Ala Val Gln  Pro Asp Leu Glu Pro  Ser Pro Gln 
    3980                 3985                 3990             


Pro Pro  Leu Ser Arg Ala Glu  Ala Ile Lys Gln Val  Lys His Phe 
    3995                 4000                 4005             


Arg Ala  Leu Gln Glu Gln Ala  Arg Thr Tyr Leu Asp  Leu Leu Cys 
    4010                 4015                 4020             


Ser Met  Cys Asp Leu Ser Asn  Ala Ser Val Lys Thr  Thr Ala Lys 
    4025                 4030                 4035             


Asp Ile  Gln Gln Thr Glu Gln  Thr Ile Glu Gln Lys  Leu Val Gln 
    4040                 4045                 4050             


Ala Gln  Asn Leu Thr Gln Gly  Trp Glu Glu Ile Lys  His Leu Lys 
    4055                 4060                 4065             


Ser Glu  Leu Trp Ile Tyr Leu  Gln Asp Ala Asp Gln  Gln Leu Gln 
    4070                 4075                 4080             


Asn Met  Lys Arg Arg His Ser  Glu Leu Glu Leu Asn  Ile Ala Gln 
    4085                 4090                 4095             


Asn Met  Val Ser Gln Val Lys  Asp Phe Val Lys Lys  Leu Gln Ser 
    4100                 4105                 4110             


Lys Gln  Ala Ser Val Asn Thr  Ile Ile Glu Lys Val  Asn Lys Leu 
    4115                 4120                 4125             


Thr Lys  Lys Glu Glu Ser Pro  Glu His Lys Glu Ile  Asn His Leu 
    4130                 4135                 4140             


Asn Asp  Gln Trp Leu Asp Leu  Cys Arg Gln Ser Asn  Asn Leu Cys 
    4145                 4150                 4155             


Leu Gln  Arg Glu Glu Asp Leu  Gln Arg Thr Arg Asp  Tyr His Asp 
    4160                 4165                 4170             


Cys Met  Asn Val Val Glu Val  Phe Leu Glu Lys Phe  Thr Thr Glu 
    4175                 4180                 4185             


Trp Asp  Asn Leu Ala Arg Ser  Asp Ala Glu Ser Thr  Ala Val His 
    4190                 4195                 4200             


Leu Glu  Ala Leu Lys Lys Leu  Ala Leu Ala Leu Gln  Glu Arg Lys 
    4205                 4210                 4215             


Tyr Ala  Ile Glu Asp Leu Lys  Asp Gln Lys Gln Lys  Met Ile Glu 
    4220                 4225                 4230             


His Leu  Asn Leu Asp Asp Lys  Glu Leu Val Lys Glu  Gln Thr Ser 
    4235                 4240                 4245             


His Leu  Glu Gln Arg Trp Phe  Gln Leu Glu Asp Leu  Ile Lys Arg 
    4250                 4255                 4260             


Lys Ile  Gln Val Ser Val Thr  Asn Leu Glu Glu Leu  Asn Val Val 
    4265                 4270                 4275             


Gln Ser  Arg Phe Gln Glu Leu  Met Glu Trp Ala Glu  Glu Gln Gln 
    4280                 4285                 4290             


Pro Asn  Ile Ala Glu Ala Leu  Lys Gln Ser Pro Pro  Pro Asp Met 
    4295                 4300                 4305             


Ala Gln  Asn Leu Leu Met Asp  His Leu Ala Ile Cys  Ser Glu Leu 
    4310                 4315                 4320             


Glu Ala  Lys Gln Met Leu Leu  Lys Ser Leu Ile Lys  Asp Ala Asp 
    4325                 4330                 4335             


Arg Val  Met Ala Asp Leu Gly  Leu Asn Glu Arg Gln  Val Ile Gln 
    4340                 4345                 4350             


Lys Ala  Leu Ser Asp Ala Gln  Ser His Val Asn Cys  Leu Ser Asp 
    4355                 4360                 4365             


Leu Val  Gly Gln Arg Arg Lys  Tyr Leu Asn Lys Ala  Leu Ser Glu 
    4370                 4375                 4380             


Lys Thr  Gln Phe Leu Met Ala  Val Phe Gln Ala Thr  Ser Gln Ile 
    4385                 4390                 4395             


Gln Gln  His Glu Arg Lys Ile  Met Phe Arg Glu His  Ile Cys Leu 
    4400                 4405                 4410             


Leu Pro  Asp Asp Val Ser Lys  Gln Val Lys Thr Cys  Lys Ser Ala 
    4415                 4420                 4425             


Gln Ala  Ser Leu Lys Thr Tyr  Gln Asn Glu Val Thr  Gly Leu Trp 
    4430                 4435                 4440             


Ala Gln  Gly Arg Glu Leu Met  Lys Glu Val Thr Glu  Gln Glu Lys 
    4445                 4450                 4455             


Ser Glu  Val Leu Gly Lys Leu  Gln Glu Leu Gln Ser  Val Tyr Asp 
    4460                 4465                 4470             


Ser Val  Leu Gln Lys Cys Ser  His Arg Leu Gln Glu  Leu Glu Lys 
    4475                 4480                 4485             


Asn Leu  Val Ser Arg Lys His  Phe Lys Glu Asp Phe  Asp Lys Ala 
    4490                 4495                 4500             


Cys His  Trp Leu Lys Gln Ala  Asp Ile Val Thr Phe  Pro Glu Ile 
    4505                 4510                 4515             


Asn Leu  Met Asn Glu Ser Ser  Glu Leu His Thr Gln  Leu Ala Lys 
    4520                 4525                 4530             


Tyr Gln  Asn Ile Leu Glu Gln  Ser Pro Glu Tyr Glu  Asn Leu Leu 
    4535                 4540                 4545             


Leu Thr  Leu Gln Arg Thr Gly  Gln Thr Ile Leu Pro  Ser Leu Asn 
    4550                 4555                 4560             


Glu Val  Asp His Ser Tyr Leu  Ser Glu Lys Leu Asn  Ala Leu Pro 
    4565                 4570                 4575             


Arg Gln  Phe Asn Val Ile Val  Ala Leu Ala Lys Asp  Lys Phe Tyr 
    4580                 4585                 4590             


Lys Val  Gln Glu Ala Ile Leu  Ala Arg Lys Glu Tyr  Ala Ser Leu 
    4595                 4600                 4605             


Ile Glu  Leu Thr Thr Gln Ser  Leu Ser Glu Leu Glu  Ala Gln Phe 
    4610                 4615                 4620             


Leu Arg  Met Ser Lys Val Pro  Thr Asp Leu Ala Val  Glu Glu Ala 
    4625                 4630                 4635             


Leu Ser  Leu Gln Asp Gly Cys  Arg Ala Ile Leu Asp  Glu Val Ala 
    4640                 4645                 4650             


Gly Leu  Gly Glu Ala Val Asp  Glu Leu Asn Gln Lys  Lys Glu Gly 
    4655                 4660                 4665             


Phe Arg  Ser Thr Gly Gln Pro  Trp Gln Pro Asp Lys  Met Leu His 
    4670                 4675                 4680             


Leu Val  Thr Leu Tyr His Arg  Leu Lys Arg Gln Thr  Glu Gln Arg 
    4685                 4690                 4695             


Val Ser  Leu Leu Glu Asp Thr  Thr Ser Ala Tyr Gln  Glu His Glu 
    4700                 4705                 4710             


Lys Met  Cys Gln Gln Leu Glu  Arg Gln Leu Lys Ser  Val Lys Glu 
    4715                 4720                 4725             


Glu Gln  Ser Lys Val Asn Glu  Glu Thr Leu Pro Ala  Glu Glu Lys 
    4730                 4735                 4740             


Leu Lys  Met Tyr His Ser Leu  Ala Gly Ser Leu Gln  Asp Ser Gly 
    4745                 4750                 4755             


Ile Val  Leu Lys Arg Val Thr  Ile His Leu Glu Asp  Leu Ala Pro 
    4760                 4765                 4770             


His Leu  Asp Pro Leu Ala Tyr  Glu Lys Ala Arg His  Gln Ile Gln 
    4775                 4780                 4785             


Ser Trp  Gln Gly Glu Leu Lys  Leu Leu Thr Ser Ala  Ile Gly Glu 
    4790                 4795                 4800             


Thr Val  Thr Glu Cys Glu Ser  Arg Met Val Gln Ser  Ile Asp Phe 
    4805                 4810                 4815             


Gln Thr  Glu Met Ser Arg Ser  Leu Asp Trp Leu Arg  Arg Val Lys 
    4820                 4825                 4830             


Ala Glu  Leu Ser Gly Pro Val  Tyr Leu Asp Leu Asn  Leu Gln Asp 
    4835                 4840                 4845             


Ile Gln  Glu Glu Ile Arg Lys  Ile Gln Ile His Gln  Glu Glu Val 
    4850                 4855                 4860             


Gln Ser  Ser Leu Arg Ile Met  Asn Ala Leu Ser His  Lys Glu Lys 
    4865                 4870                 4875             


Glu Lys  Phe Thr Lys Ala Lys  Glu Leu Ile Ser Ala  Asp Leu Glu 
    4880                 4885                 4890             


His Ser  Leu Ala Glu Leu Ser  Glu Leu Asp Gly Asp  Ile Gln Glu 
    4895                 4900                 4905             


Ala Leu  Arg Thr Arg Gln Ala  Thr Leu Thr Glu Ile  Tyr Ser Gln 
    4910                 4915                 4920             


Cys Gln  Arg Tyr Tyr Gln Val  Phe Gln Ala Ala Asn  Asp Trp Leu 
    4925                 4930                 4935             


Glu Asp  Ala Gln Glu Leu Leu  Gln Leu Ala Gly Asn  Gly Leu Asp 
    4940                 4945                 4950             


Val Glu  Ser Ala Glu Glu Asn  Leu Lys Ser His Met  Glu Phe Phe 
    4955                 4960                 4965             


Ser Thr  Glu Asp Gln Phe His  Ser Asn Leu Glu Glu  Leu His Ser 
    4970                 4975                 4980             


Leu Val  Ala Thr Leu Asp Pro  Leu Ile Lys Pro Thr  Gly Lys Glu 
    4985                 4990                 4995             


Asp Leu  Glu Gln Lys Val Ala  Ser Leu Glu Leu Arg  Ser Gln Arg 
    5000                 5005                 5010             


Met Ser  Arg Asp Ser Gly Ala  Gln Val Asp Leu Leu  Gln Arg Cys 
    5015                 5020                 5025             


Thr Ala  Gln Trp His Asp Tyr  Gln Lys Ala Arg Glu  Glu Val Ile 
    5030                 5035                 5040             


Glu Leu  Met Asn Asp Thr Glu  Lys Lys Leu Ser Glu  Phe Ser Leu 
    5045                 5050                 5055             


Leu Lys  Thr Ser Ser Ser His  Glu Ala Glu Glu Lys  Leu Ser Glu 
    5060                 5065                 5070             


His Lys  Ala Leu Val Ser Val  Val Asn Ser Phe His  Glu Lys Ile 
    5075                 5080                 5085             


Val Ala  Leu Glu Glu Lys Ala  Ser Gln Leu Glu Lys  Thr Gly Asn 
    5090                 5095                 5100             


Asp Ala  Ser Lys Ala Thr Leu  Ser Arg Ser Met Thr  Thr Val Trp 
    5105                 5110                 5115             


Gln Arg  Trp Thr Arg Leu Arg  Ala Val Ala Gln Asp  Gln Glu Lys 
    5120                 5125                 5130             


Ile Leu  Glu Asp Ala Val Asp  Glu Trp Thr Gly Phe  Asn Asn Lys 
    5135                 5140                 5145             


Val Lys  Lys Ala Thr Glu Met  Ile Asp Gln Leu Gln  Asp Lys Leu 
    5150                 5155                 5160             


Pro Gly  Ser Ser Ala Glu Lys  Ala Ser Lys Ala Glu  Leu Leu Thr 
    5165                 5170                 5175             


Leu Leu  Glu Tyr His Asp Thr  Phe Val Leu Glu Leu  Glu Gln Gln 
    5180                 5185                 5190             


Gln Ser  Ala Leu Gly Met Leu  Arg Gln Gln Thr Leu  Ser Met Leu 
    5195                 5200                 5205             


Gln Asp  Gly Ala Ala Pro Thr  Pro Gly Glu Glu Pro  Pro Leu Met 
    5210                 5215                 5220             


Gln Glu  Ile Thr Ala Met Gln  Asp Arg Cys Leu Asn  Met Gln Glu 
    5225                 5230                 5235             


Lys Val  Lys Thr Asn Gly Lys  Leu Val Lys Gln Glu  Leu Lys Asp 
    5240                 5245                 5250             


Arg Glu  Met Val Glu Thr Gln  Ile Asn Ser Val Lys  Cys Trp Val 
    5255                 5260                 5265             


Gln Glu  Thr Lys Glu Tyr Leu  Gly Asn Pro Thr Ile  Glu Ile Asp 
    5270                 5275                 5280             


Ala Gln  Leu Glu Glu Leu Gln  Ile Leu Leu Thr Glu  Ala Thr Asn 
    5285                 5290                 5295             


His Arg  Gln Asn Ile Glu Lys  Met Ala Glu Glu Gln  Lys Glu Lys 
    5300                 5305                 5310             


Tyr Leu  Gly Leu Tyr Thr Ile  Leu Pro Ser Glu Leu  Ser Leu Gln 
    5315                 5320                 5325             


Leu Ala  Glu Val Ala Leu Asp  Leu Lys Ile Arg Asp  Gln Ile Gln 
    5330                 5335                 5340             


Asp Lys  Ile Lys Glu Val Glu  Gln Ser Lys Ala Thr  Ser Gln Glu 
    5345                 5350                 5355             


Leu Ser  Arg Gln Ile Gln Lys  Leu Ala Lys Asp Leu  Thr Thr Ile 
    5360                 5365                 5370             


Leu Thr  Lys Leu Lys Ala Lys  Thr Asp Asn Val Val  Gln Ala Lys 
    5375                 5380                 5385             


Thr Asp  Gln Lys Val Leu Gly  Glu Glu Leu Asp Gly  Cys Asn Ser 
    5390                 5395                 5400             


Lys Leu  Met Glu Leu Asp Ala  Ala Val Gln Lys Phe  Leu Glu Gln 
    5405                 5410                 5415             


Asn Gly  Gln Leu Gly Lys Pro  Leu Ala Lys Lys Ile  Gly Lys Leu 
    5420                 5425                 5430             


Thr Glu  Leu His Gln Gln Thr  Ile Arg Gln Ala Glu  Asn Arg Leu 
    5435                 5440                 5445             


Ser Lys  Leu Asn Gln Ala Ala  Ser His Leu Glu Glu  Tyr Asn Glu 
    5450                 5455                 5460             


Met Leu  Glu Leu Ile Leu Lys  Trp Ile Glu Lys Ala  Lys Val Leu 
    5465                 5470                 5475             


Ala His  Gly Thr Ile Ala Trp  Asn Ser Ala Ser Gln  Leu Arg Glu 
    5480                 5485                 5490             


Gln Tyr  Ile Leu His Gln Thr  Leu Leu Glu Glu Ser  Lys Glu Ile 
    5495                 5500                 5505             


Asp Ser  Glu Leu Glu Ala Met  Thr Glu Lys Leu Gln  Tyr Leu Thr 
    5510                 5515                 5520             


Ser Val  Tyr Cys Thr Glu Lys  Met Ser Gln Gln Val  Ala Glu Leu 
    5525                 5530                 5535             


Gly Arg  Glu Thr Glu Glu Leu  Arg Gln Met Ile Lys  Ile Arg Leu 
    5540                 5545                 5550             


Gln Asn  Leu Gln Asp Ala Ala  Lys Asp Met Lys Lys  Phe Glu Ala 
    5555                 5560                 5565             


Glu Leu  Lys Lys Leu Gln Ala  Ala Leu Glu Gln Ala  Gln Ala Thr 
    5570                 5575                 5580             


Leu Thr  Ser Pro Glu Val Gly  Arg Leu Ser Leu Lys  Glu Gln Leu 
    5585                 5590                 5595             


Ser His  Arg Gln His Leu Leu  Ser Glu Met Glu Ser  Leu Lys Pro 
    5600                 5605                 5610             


Lys Val  Gln Ala Val Gln Leu  Cys Gln Ser Ala Leu  Arg Ile Pro 
    5615                 5620                 5625             


Glu Asp  Val Val Ala Ser Leu  Pro Leu Cys His Ala  Ala Leu Arg 
    5630                 5635                 5640             


Leu Gln  Glu Glu Ala Ser Arg  Leu Gln His Thr Ala  Ile Gln Gln 
    5645                 5650                 5655             


Cys Asn  Ile Met Gln Ala Ala  Val Val Gln Tyr Glu  Gln Tyr Glu 
    5660                 5665                 5670             


Gln Glu  Met Lys His Leu Gln  Gln Leu Ile Glu Gly  Ala His Arg 
    5675                 5680                 5685             


Glu Ile  Glu Asp Lys Pro Val  Ala Thr Ser Asn Ile  Gln Glu Leu 
    5690                 5695                 5700             


Gln Ala  Gln Ile Ser Arg His  Glu Glu Leu Ala Gln  Lys Ile Lys 
    5705                 5710                 5715             


Gly Tyr  Gln Glu Gln Ile Ala  Ser Leu Asn Ser Lys  Cys Lys Met 
    5720                 5725                 5730             


Leu Thr  Met Lys Ala Lys His  Ala Thr Met Leu Leu  Thr Val Thr 
    5735                 5740                 5745             


Glu Val  Glu Gly Leu Ala Glu  Gly Thr Glu Asp Leu  Asp Gly Glu 
    5750                 5755                 5760             


Leu Leu  Pro Thr Pro Ser Ala  His Pro Ser Val Val  Met Met Thr 
    5765                 5770                 5775             


Ala Gly  Arg Cys His Thr Leu  Leu Ser Pro Val Thr  Glu Glu Ser 
    5780                 5785                 5790             


Gly Glu  Glu Gly Thr Asn Ser  Glu Ile Ser Ser Pro  Pro Ala Cys 
    5795                 5800                 5805             


Arg Ser  Pro Ser Pro Val Ala  Asn Thr Asp Ala Ser  Val Asn Gln 
    5810                 5815                 5820             


Asp Ile  Ala Tyr Tyr Gln Ala  Leu Ser Ala Glu Arg  Leu Gln Thr 
    5825                 5830                 5835             


Asp Ala  Ala Lys Ile His Pro  Ser Thr Ser Ala Ser  Gln Glu Phe 
    5840                 5845                 5850             


Tyr Glu  Pro Gly Leu Glu Pro  Ser Ala Thr Ala Lys  Leu Gly Asp 
    5855                 5860                 5865             


Leu Gln  Arg Ser Trp Glu Thr  Leu Lys Asn Val Ile  Ser Glu Lys 
    5870                 5875                 5880             


Gln Arg  Thr Leu Tyr Glu Ala  Leu Glu Arg Gln Gln  Lys Tyr Gln 
    5885                 5890                 5895             


Asp Ser  Leu Gln Ser Ile Ser  Thr Lys Met Glu Ala  Ile Glu Leu 
    5900                 5905                 5910             


Lys Leu  Ser Glu Ser Pro Glu  Pro Gly Arg Ser Pro  Glu Ser Gln 
    5915                 5920                 5925             


Met Ala  Glu His Gln Ala Leu  Met Asp Glu Ile Leu  Met Leu Gln 
    5930                 5935                 5940             


Asp Glu  Ile Asn Glu Leu Gln  Ser Ser Leu Ala Glu  Glu Leu Val 
    5945                 5950                 5955             


Ser Glu  Ser Cys Glu Ala Asp  Pro Ala Glu Gln Leu  Ala Leu Gln 
    5960                 5965                 5970             


Ser Thr  Leu Thr Val Leu Ala  Glu Arg Met Ser Thr  Ile Arg Met 
    5975                 5980                 5985             


Lys Ala  Ser Gly Lys Arg Gln  Leu Leu Glu Glu Lys  Leu Asn Asp 
    5990                 5995                 6000             


Gln Leu  Glu Glu Gln Arg Gln  Glu Gln Ala Leu Gln  Arg Tyr Arg 
    6005                 6010                 6015             


Cys Glu  Ala Asp Glu Leu Asp  Ser Trp Leu Leu Ser  Thr Lys Ala 
    6020                 6025                 6030             


Thr Leu  Asp Thr Ala Leu Ser  Pro Pro Lys Glu Pro  Met Asp Met 
    6035                 6040                 6045             


Glu Ala  Gln Leu Met Asp Cys  Gln Asn Met Leu Val  Glu Ile Glu 
    6050                 6055                 6060             


Gln Lys  Val Val Ala Leu Ser  Glu Leu Ser Val His  Asn Glu Asn 
    6065                 6070                 6075             


Leu Leu  Leu Glu Gly Lys Ala  His Thr Lys Asp Glu  Ala Glu Gln 
    6080                 6085                 6090             


Leu Ala  Gly Lys Leu Arg Arg  Leu Lys Gly Ser Leu  Leu Glu Leu 
    6095                 6100                 6105             


Gln Arg  Ala Leu His Asp Lys  Gln Leu Asn Met Gln  Gly Thr Ala 
    6110                 6115                 6120             


Gln Glu  Lys Glu Glu Ser Asp  Val Asp Leu Thr Ala  Thr Gln Ser 
    6125                 6130                 6135             


Pro Gly  Val Gln Glu Trp Leu  Ala Gln Ala Arg Thr  Thr Trp Thr 
    6140                 6145                 6150             


Gln Gln  Arg Gln Ser Ser Leu  Gln Gln Gln Lys Glu  Leu Glu Gln 
    6155                 6160                 6165             


Glu Leu  Ala Glu Gln Lys Ser  Leu Leu Arg Ser Val  Ala Ser Arg 
    6170                 6175                 6180             


Gly Glu  Glu Ile Leu Ile Gln  His Ser Ala Ala Glu  Thr Ser Gly 
    6185                 6190                 6195             


Asp Ala  Gly Glu Lys Pro Asp  Val Leu Ser Gln Glu  Leu Gly Met 
    6200                 6205                 6210             


Glu Gly  Glu Lys Ser Ser Ala  Glu Asp Gln Met Arg  Met Lys Trp 
    6215                 6220                 6225             


Glu Ser  Leu His Gln Glu Phe  Ser Thr Lys Gln Lys  Leu Leu Gln 
    6230                 6235                 6240             


Asn Val  Leu Glu Gln Glu Gln  Glu Gln Val Leu Tyr  Ser Arg Pro 
    6245                 6250                 6255             


Asn Arg  Leu Leu Ser Gly Val  Pro Leu Tyr Lys Gly  Asp Val Pro 
    6260                 6265                 6270             


Thr Gln  Asp Lys Ser Ala Val  Thr Ser Leu Leu Asp  Gly Leu Asn 
    6275                 6280                 6285             


Gln Ala  Phe Glu Glu Val Ser  Ser Gln Ser Gly Gly  Ala Lys Arg 
    6290                 6295                 6300             


Gln Ser  Ile His Leu Glu Gln  Lys Leu Tyr Asp Gly  Val Ser Ala 
    6305                 6310                 6315             


Thr Ser  Thr Trp Leu Asp Asp  Val Glu Glu Arg Leu  Phe Val Ala 
    6320                 6325                 6330             


Thr Ala  Leu Leu Pro Glu Glu  Thr Glu Thr Cys Leu  Phe Asn Gln 
    6335                 6340                 6345             


Glu Ile  Leu Ala Lys Asp Ile  Lys Glu Met Ser Glu  Glu Met Asp 
    6350                 6355                 6360             


Lys Asn  Lys Asn Leu Phe Ser  Gln Ala Phe Pro Glu  Asn Gly Asp 
    6365                 6370                 6375             


Asn Arg  Asp Val Ile Glu Asp  Thr Leu Gly Cys Leu  Leu Gly Arg 
    6380                 6385                 6390             


Leu Ser  Leu Leu Asp Ser Val  Val Asn Gln Arg Cys  His Gln Met 
    6395                 6400                 6405             


Lys Glu  Arg Leu Gln Gln Ile  Leu Asn Phe Gln Asn  Asp Leu Lys 
    6410                 6415                 6420             


Val Leu  Phe Thr Ser Leu Ala  Asp Asn Lys Tyr Ile  Ile Leu Gln 
    6425                 6430                 6435             


Lys Leu  Ala Asn Val Phe Glu  Gln Pro Val Ala Glu  Gln Ile Glu 
    6440                 6445                 6450             


Ala Ile  Gln Gln Ala Glu Asp  Gly Leu Lys Glu Phe  Asp Ala Gly 
    6455                 6460                 6465             


Ile Ile  Glu Leu Lys Arg Arg  Gly Asp Lys Leu Gln  Val Glu Gln 
    6470                 6475                 6480             


Pro Ser  Met Gln Glu Leu Ser  Lys Leu Gln Asp Met  Tyr Asp Glu 
    6485                 6490                 6495             


Leu Met  Met Ile Ile Gly Ser  Arg Arg Ser Gly Leu  Asn Gln Asn 
    6500                 6505                 6510             


Leu Thr  Leu Lys Ser Gln Tyr  Glu Arg Ala Leu Gln  Asp Leu Ala 
    6515                 6520                 6525             


Asp Leu  Leu Glu Thr Gly Gln  Glu Lys Met Ala Gly  Asp Gln Lys 
    6530                 6535                 6540             


Ile Ile  Val Ser Ser Lys Glu  Glu Ile Gln Gln Leu  Leu Asp Lys 
    6545                 6550                 6555             


His Lys  Glu Tyr Phe Gln Gly  Leu Glu Ser His Met  Ile Leu Thr 
    6560                 6565                 6570             


Glu Thr  Leu Phe Arg Lys Ile  Ile Ser Phe Ala Val  Gln Lys Glu 
    6575                 6580                 6585             


Thr Gln  Phe His Thr Glu Leu  Met Ala Gln Ala Ser  Ala Val Leu 
    6590                 6595                 6600             


Lys Arg  Ala His Lys Arg Gly  Val Glu Leu Glu Tyr  Ile Leu Glu 
    6605                 6610                 6615             


Thr Trp  Ser His Leu Asp Glu  Asp Gln Gln Glu Leu  Ser Arg Gln 
    6620                 6625                 6630             


Leu Glu  Val Val Glu Ser Ser  Ile Pro Ser Val Gly  Leu Val Glu 
    6635                 6640                 6645             


Glu Asn  Glu Asp Arg Leu Ile  Asp Arg Ile Thr Leu  Tyr Gln His 
    6650                 6655                 6660             


Leu Lys  Ser Ser Leu Asn Glu  Tyr Gln Pro Lys Leu  Tyr Gln Val 
    6665                 6670                 6675             


Leu Asp  Asp Gly Lys Arg Leu  Leu Ile Ser Ile Ser  Cys Ser Asp 
    6680                 6685                 6690             


Leu Glu  Ser Gln Leu Asn Gln  Leu Gly Glu Cys Trp  Leu Ser Asn 
    6695                 6700                 6705             


Thr Asn  Lys Met Ser Lys Glu  Leu His Arg Leu Glu  Thr Ile Leu 
    6710                 6715                 6720             


Lys His  Trp Thr Arg Tyr Gln  Ser Glu Ser Ala Asp  Leu Ile His 
    6725                 6730                 6735             


Trp Leu  Gln Ser Ala Lys Asp  Arg Leu Glu Phe Trp  Thr Gln Gln 
    6740                 6745                 6750             


Ser Val  Thr Val Pro Gln Glu  Leu Glu Met Val Arg  Asp His Leu 
    6755                 6760                 6765             


Asn Ala  Phe Leu Glu Phe Ser  Lys Glu Val Asp Ala  Gln Ser Ser 
    6770                 6775                 6780             


Leu Lys  Ser Ser Val Leu Ser  Thr Gly Asn Gln Leu  Leu Arg Leu 
    6785                 6790                 6795             


Lys Lys  Val Asp Thr Ala Thr  Leu Arg Ser Glu Leu  Ser Arg Ile 
    6800                 6805                 6810             


Asp Ser  Gln Trp Thr Asp Leu  Leu Thr Asn Ile Pro  Ala Val Gln 
    6815                 6820                 6825             


Glu Lys  Leu His Gln Leu Gln  Met Asp Lys Leu Pro  Ser Arg His 
    6830                 6835                 6840             


Ala Ile  Ser Glu Val Met Ser  Trp Ile Ser Leu Met  Glu Asn Val 
    6845                 6850                 6855             


Ile Gln  Lys Asp Glu Asp Asn  Ile Lys Asn Ser Ile  Gly Tyr Lys 
    6860                 6865                 6870             


Ala Ile  His Glu Tyr Leu Gln  Lys Tyr Lys Gly Phe  Lys Ile Asp 
    6875                 6880                 6885             


Ile Asn  Cys Lys Gln Leu Thr  Val Asp Phe Val Asn  Gln Ser Val 
    6890                 6895                 6900             


Leu Gln  Ile Ser Ser Gln Asp  Val Glu Ser Lys Arg  Ser Asp Lys 
    6905                 6910                 6915             


Thr Asp  Phe Ala Glu Gln Leu  Gly Ala Met Asn Lys  Ser Trp Gln 
    6920                 6925                 6930             


Ile Leu  Gln Gly Leu Val Thr  Glu Lys Ile Gln Leu  Leu Glu Gly 
    6935                 6940                 6945             


Leu Leu  Glu Ser Trp Ser Glu  Tyr Glu Asn Asn Val  Gln Cys Leu 
    6950                 6955                 6960             


Lys Thr  Trp Phe Glu Thr Gln  Glu Lys Arg Leu Lys  Gln Gln His 
    6965                 6970                 6975             


Arg Ile  Gly Asp Gln Ala Ser  Val Gln Asn Ala Leu  Lys Asp Cys 
    6980                 6985                 6990             


Gln Asp  Leu Glu Asp Leu Ile  Lys Ala Lys Glu Lys  Glu Val Glu 
    6995                 7000                 7005             


Lys Ile  Glu Gln Asn Gly Leu  Ala Leu Ile Gln Asn  Lys Lys Glu 
    7010                 7015                 7020             


Asp Val  Ser Ser Ile Val Met  Ser Thr Leu Arg Glu  Leu Gly Gln 
    7025                 7030                 7035             


Thr Trp  Ala Asn Leu Asp His  Met Val Gly Gln Leu  Lys Ile Leu 
    7040                 7045                 7050             


Leu Lys  Ser Val Leu Asp Gln  Trp Ser Ser His Lys  Val Ala Phe 
    7055                 7060                 7065             


Asp Lys  Ile Asn Ser Tyr Leu  Met Glu Ala Arg Tyr  Ser Leu Ser 
    7070                 7075                 7080             


Arg Phe  Arg Leu Leu Thr Gly  Ser Leu Glu Ala Val  Gln Val Gln 
    7085                 7090                 7095             


Val Asp  Asn Leu Gln Asn Leu  Gln Asp Asp Leu Glu  Lys Gln Glu 
    7100                 7105                 7110             


Arg Ser  Leu Gln Lys Phe Gly  Ser Ile Thr Asn Gln  Leu Leu Lys 
    7115                 7120                 7125             


Glu Cys  His Pro Pro Val Thr  Glu Thr Leu Thr Asn  Thr Leu Lys 
    7130                 7135                 7140             


Glu Val  Asn Met Arg Trp Asn  Asn Leu Leu Glu Glu  Ile Ala Glu 
    7145                 7150                 7155             


Gln Leu  Gln Ser Ser Lys Ala  Leu Leu Gln Leu Trp  Gln Arg Tyr 
    7160                 7165                 7170             


Lys Asp  Tyr Ser Lys Gln Cys  Ala Ser Thr Val Gln  Gln Gln Glu 
    7175                 7180                 7185             


Asp Arg  Thr Asn Glu Leu Leu  Lys Ala Ala Thr Asn  Lys Asp Ile 
    7190                 7195                 7200             


Ala Asp  Asp Glu Val Ala Thr  Trp Ile Gln Asp Cys  Asn Asp Leu 
    7205                 7210                 7215             


Leu Lys  Gly Leu Gly Thr Val  Lys Asp Ser Leu Phe  Phe Leu His 
    7220                 7225                 7230             


Glu Leu  Gly Glu Gln Leu Lys  Gln Gln Val Asp Ala  Ser Ala Ala 
    7235                 7240                 7245             


Ser Ala  Ile Gln Ser Asp Gln  Leu Ser Leu Ser Gln  His Leu Cys 
    7250                 7255                 7260             


Ala Leu  Glu Gln Ala Leu Cys  Lys Gln Gln Thr Ser  Leu Gln Ala 
    7265                 7270                 7275             


Gly Val  Leu Asp Tyr Glu Thr  Phe Ala Lys Ser Leu  Glu Ala Leu 
    7280                 7285                 7290             


Glu Ala  Trp Ile Val Glu Ala  Glu Glu Ile Leu Gln  Gly Gln Asp 
    7295                 7300                 7305             


Pro Ser  His Ser Ser Asp Leu  Ser Thr Ile Gln Glu  Arg Met Glu 
    7310                 7315                 7320             


Glu Leu  Lys Gly Gln Met Leu  Lys Phe Ser Ser Met  Ala Pro Asp 
    7325                 7330                 7335             


Leu Asp  Arg Leu Asn Glu Leu  Gly Tyr Arg Leu Pro  Leu Asn Asp 
    7340                 7345                 7350             


Lys Glu  Ile Lys Arg Met Gln  Asn Leu Asn Arg His  Trp Ser Leu 
    7355                 7360                 7365             


Ile Ser  Ser Gln Thr Thr Glu  Arg Phe Ser Lys Leu  Gln Ser Phe 
    7370                 7375                 7380             


Leu Leu  Gln His Gln Thr Phe  Leu Glu Lys Cys Glu  Thr Trp Met 
    7385                 7390                 7395             


Glu Phe  Leu Val Gln Thr Glu  Gln Lys Leu Ala Val  Glu Ile Ser 
    7400                 7405                 7410             


Gly Asn  Tyr Gln His Leu Leu  Glu Gln Gln Arg Ala  His Glu Leu 
    7415                 7420                 7425             


Phe Gln  Ala Glu Met Phe Ser  Arg Gln Gln Ile Leu  His Ser Ile 
    7430                 7435                 7440             


Ile Ile  Asp Gly Gln Arg Leu  Leu Glu Gln Gly Gln  Val Asp Asp 
    7445                 7450                 7455             


Arg Asp  Glu Phe Asn Leu Lys  Leu Thr Leu Leu Ser  Asn Gln Trp 
    7460                 7465                 7470             


Gln Gly  Val Ile Arg Arg Ala  Gln Gln Arg Arg Gly  Ile Ile Asp 
    7475                 7480                 7485             


Ser Gln  Ile Arg Gln Trp Gln  Arg Tyr Arg Glu Met  Ala Glu Lys 
    7490                 7495                 7500             


Leu Arg  Lys Trp Leu Val Glu  Val Ser Tyr Leu Pro  Met Ser Gly 
    7505                 7510                 7515             


Leu Gly  Ser Val Pro Ile Pro  Leu Gln Gln Ala Arg  Thr Leu Phe 
    7520                 7525                 7530             


Asp Glu  Val Gln Phe Lys Glu  Lys Val Phe Leu Arg  Gln Gln Gly 
    7535                 7540                 7545             


Ser Tyr  Ile Leu Thr Val Glu  Ala Gly Lys Gln Leu  Leu Leu Ser 
    7550                 7555                 7560             


Ala Asp  Ser Gly Ala Glu Ala  Ala Leu Gln Ala Glu  Leu Ala Glu 
    7565                 7570                 7575             


Ile Gln  Glu Lys Trp Lys Ser  Ala Ser Met Arg Leu  Glu Glu Gln 
    7580                 7585                 7590             


Lys Lys  Lys Leu Ala Phe Leu  Leu Lys Asp Trp Glu  Lys Cys Glu 
    7595                 7600                 7605             


Lys Gly  Ile Ala Asp Ser Leu  Glu Lys Leu Arg Thr  Phe Lys Lys 
    7610                 7615                 7620             


Lys Leu  Ser Gln Ser Leu Pro  Asp His His Glu Glu  Leu His Ala 
    7625                 7630                 7635             


Glu Gln  Met Arg Cys Lys Glu  Leu Glu Asn Ala Val  Gly Ser Trp 
    7640                 7645                 7650             


Thr Asp  Asp Leu Thr Gln Leu  Ser Leu Leu Lys Asp  Thr Leu Ser 
    7655                 7660                 7665             


Ala Tyr  Ile Ser Ala Asp Asp  Ile Ser Ile Leu Asn  Glu Arg Val 
    7670                 7675                 7680             


Glu Leu  Leu Gln Arg Gln Trp  Glu Glu Leu Cys His  Gln Leu Ser 
    7685                 7690                 7695             


Leu Arg  Arg Gln Gln Ile Gly  Glu Arg Leu Asn Glu  Trp Ala Val 
    7700                 7705                 7710             


Phe Ser  Glu Lys Asn Lys Glu  Leu Cys Glu Trp Leu  Thr Gln Met 
    7715                 7720                 7725             


Glu Ser  Lys Val Ser Gln Asn  Gly Asp Ile Leu Ile  Glu Glu Met 
    7730                 7735                 7740             


Ile Glu  Lys Leu Lys Lys Asp  Tyr Gln Glu Glu Ile  Ala Ile Ala 
    7745                 7750                 7755             


Gln Glu  Asn Lys Ile Gln Leu  Gln Gln Met Gly Glu  Arg Leu Ala 
    7760                 7765                 7770             


Lys Ala  Ser His Glu Ser Lys  Ala Ser Glu Ile Glu  Tyr Lys Leu 
    7775                 7780                 7785             


Gly Lys  Val Asn Asp Arg Trp  Gln His Leu Leu Asp  Leu Ile Ala 
    7790                 7795                 7800             


Ala Arg  Val Lys Lys Leu Lys  Glu Thr Leu Val Ala  Val Gln Gln 
    7805                 7810                 7815             


Leu Asp  Lys Asn Met Ser Ser  Leu Arg Thr Trp Leu  Ala His Ile 
    7820                 7825                 7830             


Glu Ser  Glu Leu Ala Lys Pro  Ile Val Tyr Asp Ser  Cys Asn Ser 
    7835                 7840                 7845             


Glu Glu  Ile Gln Arg Lys Leu  Asn Glu Gln Gln Glu  Leu Gln Arg 
    7850                 7855                 7860             


Asp Ile  Glu Lys His Ser Thr  Gly Val Ala Ser Val  Leu Asn Leu 
    7865                 7870                 7875             


Cys Glu  Val Leu Leu His Asp  Cys Asp Ala Cys Ala  Thr Asp Ala 
    7880                 7885                 7890             


Glu Cys  Asp Ser Ile Gln Gln  Ala Thr Arg Asn Leu  Asp Arg Arg 
    7895                 7900                 7905             


Trp Arg  Asn Ile Cys Ala Met  Ser Met Glu Arg Arg  Leu Lys Ile 
    7910                 7915                 7920             


Glu Glu  Thr Trp Arg Leu Trp  Gln Lys Phe Leu Asp  Asp Tyr Ser 
    7925                 7930                 7935             


Arg Phe  Glu Asp Trp Leu Lys  Ser Ser Glu Arg Thr  Ala Ala Phe 
    7940                 7945                 7950             


Pro Ser  Ser Ser Gly Val Ile  Tyr Thr Val Ala Lys  Glu Glu Leu 
    7955                 7960                 7965             


Lys Lys  Phe Glu Ala Phe Gln  Arg Gln Val His Glu  Cys Leu Thr 
    7970                 7975                 7980             


Gln Leu  Glu Leu Ile Asn Lys  Gln Tyr Arg Arg Leu  Ala Arg Glu 
    7985                 7990                 7995             


Asn Arg  Thr Asp Ser Ala Cys  Ser Leu Lys Gln Met  Val His Glu 
    8000                 8005                 8010             


Gly Asn  Gln Arg Trp Asp Asn  Leu Gln Lys Arg Val  Thr Ser Ile 
    8015                 8020                 8025             


Leu Arg  Arg Leu Lys His Phe  Ile Gly Gln Arg Glu  Glu Phe Glu 
    8030                 8035                 8040             


Thr Ala  Arg Asp Ser Ile Leu  Val Trp Leu Thr Glu  Met Asp Leu 
    8045                 8050                 8055             


Gln Leu  Thr Asn Ile Glu His  Phe Ser Glu Cys Asp  Val Gln Ala 
    8060                 8065                 8070             


Lys Ile  Lys Gln Leu Lys Ala  Phe Gln Gln Glu Ile  Ser Leu Asn 
    8075                 8080                 8085             


His Asn  Lys Ile Glu Gln Ile  Ile Ala Gln Gly Glu  Gln Leu Ile 
    8090                 8095                 8100             


Glu Lys  Ser Glu Pro Leu Asp  Ala Ala Ile Ile Glu  Glu Glu Leu 
    8105                 8110                 8115             


Asp Glu  Leu Arg Arg Tyr Cys  Gln Glu Val Phe Gly  Arg Val Glu 
    8120                 8125                 8130             


Arg Tyr  His Lys Lys Leu Ile  Arg Leu Pro Leu Pro  Asp Asp Glu 
    8135                 8140                 8145             


His Asp  Leu Ser Asp Arg Glu  Leu Glu Leu Glu Asp  Ser Ala Ala 
    8150                 8155                 8160             


Leu Ser  Asp Leu His Trp His  Asp Arg Ser Ala Asp  Ser Leu Leu 
    8165                 8170                 8175             


Ser Pro  Gln Pro Ser Ser Asn  Leu Ser Leu Ser Leu  Ala Gln Pro 
    8180                 8185                 8190             


Leu Arg  Ser Glu Arg Ser Gly  Arg Asp Thr Pro Ala  Ser Val Asp 
    8195                 8200                 8205             


Ser Ile  Pro Leu Glu Trp Asp  His Asp Tyr Asp Leu  Ser Arg Asp 
    8210                 8215                 8220             


Leu Glu  Ser Ala Met Ser Arg  Ala Leu Pro Ser Glu  Asp Glu Glu 
    8225                 8230                 8235             


Gly Gln  Asp Asp Lys Asp Phe  Tyr Leu Arg Gly Ala  Val Gly Leu 
    8240                 8245                 8250             


Ser Asp  Val Met Ile Pro Glu  Ser Pro Glu Ala Tyr  Val Lys Leu 
    8255                 8260                 8265             


Thr Glu  Asn Ala Ile Lys Asn  Thr Ser Gly Asp His  Ser Ala Leu 
    8270                 8275                 8280             


Glu Ser  Gln Ile Arg Gln Leu  Gly Lys Ala Leu Asp  Asp Ser Arg 
    8285                 8290                 8295             


Phe Gln  Ile Gln Gln Thr Glu  Asn Ile Ile Arg Ser  Lys Thr Pro 
    8300                 8305                 8310             


Thr Gly  Pro Glu Leu Asp Thr  Ser Tyr Lys Gly Tyr  Met Lys Leu 
    8315                 8320                 8325             


Leu Gly  Glu Cys Ser Ser Ser  Ile Asp Ser Val Lys  Arg Leu Glu 
    8330                 8335                 8340             


His Lys  Leu Lys Glu Glu Glu  Glu Ser Leu Pro Gly  Phe Val Asn 
    8345                 8350                 8355             


Leu His  Ser Thr Glu Thr Gln  Thr Ala Gly Val Ile  Asp Arg Trp 
    8360                 8365                 8370             


Glu Leu  Leu Gln Ala Gln Ala  Leu Ser Lys Glu Leu  Arg Met Lys 
    8375                 8380                 8385             


Gln Asn  Leu Gln Lys Trp Gln  Gln Phe Asn Ser Asp  Leu Asn Ser 
    8390                 8395                 8400             


Ile Trp  Ala Trp Leu Gly Asp  Thr Glu Glu Glu Leu  Glu Gln Leu 
    8405                 8410                 8415             


Gln Arg  Leu Glu Leu Ser Thr  Asp Ile Gln Thr Ile  Glu Leu Gln 
    8420                 8425                 8430             


Ile Lys  Lys Leu Lys Glu Leu  Gln Lys Ala Val Asp  His Arg Lys 
    8435                 8440                 8445             


Ala Ile  Ile Leu Ser Ile Asn  Leu Cys Ser Pro Glu  Phe Thr Gln 
    8450                 8455                 8460             


Ala Asp  Ser Lys Glu Ser Arg  Asp Leu Gln Asp Arg  Leu Ser Gln 
    8465                 8470                 8475             


Met Asn  Gly Arg Trp Asp Arg  Val Cys Ser Leu Leu  Glu Glu Trp 
    8480                 8485                 8490             


Arg Gly  Leu Leu Gln Asp Ala  Leu Met Gln Cys Gln  Gly Phe His 
    8495                 8500                 8505             


Glu Met  Ser His Gly Leu Leu  Leu Met Leu Glu Asn  Ile Asp Arg 
    8510                 8515                 8520             


Arg Lys  Asn Glu Ile Val Pro  Ile Asp Ser Asn Leu  Asp Ala Glu 
    8525                 8530                 8535             


Ile Leu  Gln Asp His His Lys  Gln Leu Met Gln Ile  Lys His Glu 
    8540                 8545                 8550             


Leu Leu  Glu Ser Gln Leu Arg  Val Ala Ser Leu Gln  Asp Met Ser 
    8555                 8560                 8565             


Cys Gln  Leu Leu Val Asn Ala  Glu Gly Thr Asp Cys  Leu Glu Ala 
    8570                 8575                 8580             


Lys Glu  Lys Val His Val Ile  Gly Asn Arg Leu Lys  Leu Leu Leu 
    8585                 8590                 8595             


Lys Glu  Val Ser Arg His Ile  Lys Glu Leu Glu Lys  Leu Leu Asp 
    8600                 8605                 8610             


Val Ser  Ser Ser Gln Gln Asp  Leu Ser Ser Trp Ser  Ser Ala Asp 
    8615                 8620                 8625             


Glu Leu  Asp Thr Ser Gly Ser  Val Ser Pro Thr Ser  Gly Arg Ser 
    8630                 8635                 8640             


Thr Pro  Asn Arg Gln Lys Thr  Pro Arg Gly Lys Cys  Ser Leu Ser 
    8645                 8650                 8655             


Gln Pro  Gly Pro Ser Val Ser  Ser Pro His Ser Arg  Ser Thr Lys 
    8660                 8665                 8670             


Gly Gly  Ser Asp Ser Ser Leu  Ser Glu Pro Gly Pro  Gly Arg Ser 
    8675                 8680                 8685             


Gly Arg  Gly Phe Leu Phe Arg  Val Leu Arg Ala Ala  Leu Pro Leu 
    8690                 8695                 8700             


Gln Leu  Leu Leu Leu Leu Leu  Ile Gly Leu Ala Cys  Leu Val Pro 
    8705                 8710                 8715             


Met Ser  Glu Glu Asp Tyr Ser  Cys Ala Leu Ser Asn  Asn Phe Ala 
    8720                 8725                 8730             


Arg Ser  Phe His Pro Met Leu  Arg Tyr Thr Asn Gly  Pro Pro Pro 
    8735                 8740                 8745             


Leu 
    


<210>  1403
<211>  349
<212>  PRT
<213>  Human

<400>  1403

Met Ser Lys Ser Lys Asp Asp Ala Pro His Glu Leu Glu Ser Gln Phe 
1               5                   10                  15      


Ile Leu Arg Leu Pro Pro Glu Tyr Ala Ser Thr Val Arg Arg Ala Val 
            20                  25                  30          


Gln Ser Gly His Val Asn Leu Lys Asp Arg Leu Thr Ile Glu Leu His 
        35                  40                  45              


Pro Asp Gly Arg His Gly Ile Val Arg Val Asp Arg Val Pro Leu Ala 
    50                  55                  60                  


Ser Lys Leu Val Asp Leu Pro Cys Val Met Glu Ser Leu Lys Thr Ile 
65                  70                  75                  80  


Asp Lys Lys Thr Phe Tyr Lys Thr Ala Asp Ile Cys Gln Met Leu Val 
                85                  90                  95      


Ser Thr Val Asp Gly Asp Leu Tyr Pro Pro Val Glu Glu Pro Val Ala 
            100                 105                 110         


Ser Thr Asp Pro Lys Ala Ser Lys Lys Lys Asp Lys Asp Lys Glu Lys 
        115                 120                 125             


Lys Phe Ile Trp Asn His Gly Ile Thr Leu Pro Leu Lys Asn Val Arg 
    130                 135                 140                 


Lys Arg Arg Phe Arg Lys Thr Ala Lys Lys Lys Tyr Ile Glu Ser Pro 
145                 150                 155                 160 


Asp Val Glu Lys Glu Val Lys Arg Leu Leu Ser Thr Asp Ala Glu Ala 
                165                 170                 175     


Val Ser Thr Arg Trp Glu Ile Ile Ala Glu Asp Glu Thr Lys Glu Ala 
            180                 185                 190         


Glu Asn Gln Gly Leu Asp Ile Ser Ser Pro Gly Met Ser Gly His Arg 
        195                 200                 205             


Gln Gly His Asp Ser Leu Glu His Asp Glu Leu Arg Glu Ile Phe Asn 
    210                 215                 220                 


Asp Leu Ser Ser Ser Ser Glu Asp Glu Asp Glu Thr Gln His Gln Asp 
225                 230                 235                 240 


Glu Glu Asp Ile Asn Ile Ile Asp Thr Glu Glu Asp Leu Glu Arg Gln 
                245                 250                 255     


Leu Gln Asp Lys Leu Asn Glu Ser Asp Glu Gln His Gln Glu Asn Glu 
            260                 265                 270         


Gly Thr Asn Gln Leu Val Met Gly Ile Gln Lys Gln Ile Asp Asn Met 
        275                 280                 285             


Lys Gly Lys Leu Gln Glu Thr Gln Asp Arg Ala Lys Arg Gln Glu Asp 
    290                 295                 300                 


Leu Ile Met Lys Val Glu Asn Leu Ala Leu Lys Asn Arg Phe Gln Ala 
305                 310                 315                 320 


Val Leu Asp Glu Leu Lys Gln Lys Glu Asp Arg Glu Lys Glu Gln Leu 
                325                 330                 335     


Ser Ser Leu Gln Glu Glu Leu Glu Ser Leu Leu Glu Lys 
            340                 345                 


<210>  1404
<211>  345
<212>  PRT
<213>  Human

<400>  1404

Met Leu Ala Ala Asn Pro Gly Lys Thr Pro Ile Ser Leu Leu Gln Glu 
1               5                   10                  15      


Tyr Gly Thr Arg Ile Gly Lys Thr Pro Val Tyr Asp Leu Leu Lys Ala 
            20                  25                  30          


Glu Gly Gln Ala His Gln Pro Asn Phe Thr Phe Arg Val Thr Val Gly 
        35                  40                  45              


Asp Thr Ser Cys Thr Gly Gln Gly Pro Ser Lys Lys Ala Ala Lys His 
    50                  55                  60                  


Lys Ala Ala Glu Val Ala Leu Lys His Leu Lys Gly Gly Ser Met Leu 
65                  70                  75                  80  


Glu Pro Ala Leu Glu Asp Ser Ser Ser Phe Ser Pro Leu Asp Ser Ser 
                85                  90                  95      


Leu Pro Glu Asp Ile Pro Val Phe Thr Ala Ala Ala Ala Ala Thr Pro 
            100                 105                 110         


Val Pro Ser Val Val Leu Thr Arg Ser Pro Pro Met Glu Leu Gln Pro 
        115                 120                 125             


Pro Val Ser Pro Gln Gln Ser Glu Cys Asn Pro Val Gly Ala Leu Gln 
    130                 135                 140                 


Glu Leu Val Val Gln Lys Gly Trp Arg Leu Pro Glu Tyr Thr Val Thr 
145                 150                 155                 160 


Gln Glu Ser Gly Pro Ala His Arg Lys Glu Phe Thr Met Thr Cys Arg 
                165                 170                 175     


Val Glu Arg Phe Ile Glu Ile Gly Ser Gly Thr Ser Lys Lys Leu Ala 
            180                 185                 190         


Lys Arg Asn Ala Ala Ala Lys Met Leu Leu Arg Val His Thr Val Pro 
        195                 200                 205             


Leu Asp Ala Arg Asp Gly Asn Glu Val Glu Pro Asp Asp Asp His Phe 
    210                 215                 220                 


Ser Ile Gly Val Gly Ser Arg Leu Asp Gly Leu Arg Asn Arg Gly Pro 
225                 230                 235                 240 


Gly Cys Thr Trp Asp Ser Leu Arg Asn Ser Val Gly Glu Lys Ile Leu 
                245                 250                 255     


Ser Leu Arg Ser Cys Ser Leu Gly Ser Leu Gly Ala Leu Gly Pro Ala 
            260                 265                 270         


Cys Cys Arg Val Leu Ser Glu Leu Ser Glu Glu Gln Ala Phe His Val 
        275                 280                 285             


Ser Tyr Leu Asp Ile Glu Glu Leu Ser Leu Ser Gly Leu Cys Gln Cys 
    290                 295                 300                 


Leu Val Glu Leu Ser Thr Gln Pro Ala Thr Val Cys His Gly Ser Ala 
305                 310                 315                 320 


Thr Thr Arg Glu Ala Ala Arg Gly Glu Ala Ala Arg Arg Ala Leu Gln 
                325                 330                 335     


Tyr Leu Lys Ile Met Ala Gly Ser Lys 
            340                 345 


<210>  1405
<211>  958
<212>  PRT
<213>  Human

<400>  1405

Met Ala Glu Ala Arg Lys Arg Arg Glu Leu Leu Pro Leu Ile Tyr His 
1               5                   10                  15      


His Leu Leu Arg Ala Gly Tyr Val Arg Ala Ala Arg Glu Val Lys Glu 
            20                  25                  30          


Gln Ser Gly Gln Lys Cys Phe Leu Ala Gln Pro Val Thr Leu Leu Asp 
        35                  40                  45              


Ile Tyr Thr His Trp Gln Gln Thr Ser Glu Leu Gly Arg Lys Arg Lys 
    50                  55                  60                  


Ala Glu Glu Asp Ala Ala Leu Gln Ala Lys Lys Thr Arg Val Ser Asp 
65                  70                  75                  80  


Pro Ile Ser Thr Ser Glu Ser Ser Glu Glu Glu Glu Glu Ala Glu Ala 
                85                  90                  95      


Glu Thr Ala Lys Ala Thr Pro Arg Leu Ala Ser Thr Asn Ser Ser Val 
            100                 105                 110         


Leu Gly Ala Asp Leu Pro Ser Ser Met Lys Glu Lys Ala Lys Ala Glu 
        115                 120                 125             


Thr Glu Lys Ala Gly Lys Thr Gly Asn Ser Met Pro His Pro Ala Thr 
    130                 135                 140                 


Gly Lys Thr Val Ala Asn Leu Leu Ser Gly Lys Ser Pro Arg Lys Ser 
145                 150                 155                 160 


Ala Glu Pro Ser Ala Asn Thr Thr Leu Val Ser Glu Thr Glu Glu Glu 
                165                 170                 175     


Gly Ser Val Pro Ala Phe Gly Ala Ala Ala Lys Pro Gly Met Val Ser 
            180                 185                 190         


Ala Gly Gln Ala Asp Ser Ser Ser Glu Asp Thr Ser Ser Ser Ser Asp 
        195                 200                 205             


Glu Thr Asp Val Glu Gly Lys Pro Ser Val Lys Pro Ala Gln Val Lys 
    210                 215                 220                 


Ala Ser Ser Val Ser Thr Lys Glu Ser Pro Ala Arg Lys Ala Ala Pro 
225                 230                 235                 240 


Ala Pro Gly Lys Val Gly Asp Val Thr Pro Gln Val Lys Gly Gly Ala 
                245                 250                 255     


Leu Pro Pro Ala Lys Arg Ala Lys Lys Pro Glu Glu Glu Ser Glu Ser 
            260                 265                 270         


Ser Glu Glu Gly Ser Glu Ser Glu Glu Glu Ala Pro Ala Gly Thr Arg 
        275                 280                 285             


Ser Gln Val Lys Ala Ser Glu Lys Ile Leu Gln Val Arg Ala Ala Ser 
    290                 295                 300                 


Ala Pro Ala Lys Gly Thr Pro Gly Lys Gly Ala Thr Pro Ala Pro Pro 
305                 310                 315                 320 


Gly Lys Ala Gly Ala Val Ala Ser Gln Thr Lys Ala Gly Lys Pro Glu 
                325                 330                 335     


Glu Asp Ser Glu Ser Ser Ser Glu Glu Ser Ser Asp Ser Glu Glu Glu 
            340                 345                 350         


Thr Pro Ala Ala Lys Ala Leu Leu Gln Ala Lys Ala Ser Gly Lys Thr 
        355                 360                 365             


Ser Gln Val Gly Ala Ala Ser Ala Pro Ala Lys Glu Ser Pro Arg Lys 
    370                 375                 380                 


Gly Ala Ala Pro Ala Pro Pro Gly Lys Thr Gly Pro Ala Val Ala Lys 
385                 390                 395                 400 


Ala Gln Ala Gly Lys Arg Glu Glu Asp Ser Gln Ser Ser Ser Glu Glu 
                405                 410                 415     


Ser Asp Ser Glu Glu Glu Ala Pro Ala Gln Ala Lys Pro Ser Gly Lys 
            420                 425                 430         


Ala Pro Gln Val Arg Ala Ala Ser Ala Pro Ala Lys Glu Ser Pro Arg 
        435                 440                 445             


Lys Gly Ala Ala Pro Ala Pro Pro Arg Lys Thr Gly Pro Ala Ala Ala 
    450                 455                 460                 


Gln Val Gln Val Gly Lys Gln Glu Glu Asp Ser Arg Ser Ser Ser Glu 
465                 470                 475                 480 


Glu Ser Asp Ser Asp Arg Glu Ala Leu Ala Ala Met Asn Ala Ala Gln 
                485                 490                 495     


Val Lys Pro Leu Gly Lys Ser Pro Gln Val Lys Pro Ala Ser Thr Met 
            500                 505                 510         


Gly Met Gly Pro Leu Gly Lys Gly Ala Gly Pro Val Pro Pro Gly Lys 
        515                 520                 525             


Val Gly Pro Ala Thr Pro Ser Ala Gln Val Gly Lys Trp Glu Glu Asp 
    530                 535                 540                 


Ser Glu Ser Ser Ser Glu Glu Ser Ser Asp Ser Ser Asp Gly Glu Val 
545                 550                 555                 560 


Pro Thr Ala Val Ala Pro Ala Gln Glu Lys Ser Leu Gly Asn Ile Leu 
                565                 570                 575     


Gln Ala Lys Pro Thr Ser Ser Pro Ala Lys Gly Pro Pro Gln Lys Ala 
            580                 585                 590         


Gly Pro Val Ala Val Gln Val Lys Ala Glu Lys Pro Met Asp Asn Ser 
        595                 600                 605             


Glu Ser Ser Glu Glu Ser Ser Asp Ser Ala Asp Ser Glu Glu Ala Pro 
    610                 615                 620                 


Ala Ala Met Thr Ala Ala Gln Ala Lys Pro Ala Leu Lys Ile Pro Gln 
625                 630                 635                 640 


Thr Lys Ala Cys Pro Lys Lys Thr Asn Thr Thr Ala Ser Ala Lys Val 
                645                 650                 655     


Ala Pro Val Arg Val Gly Thr Gln Ala Pro Arg Lys Ala Gly Thr Ala 
            660                 665                 670         


Thr Ser Pro Ala Gly Ser Ser Pro Ala Val Ala Gly Gly Thr Gln Arg 
        675                 680                 685             


Pro Ala Glu Asp Ser Ser Ser Ser Glu Glu Ser Asp Ser Glu Glu Glu 
    690                 695                 700                 


Lys Thr Gly Leu Ala Val Thr Val Gly Gln Ala Lys Ser Val Gly Lys 
705                 710                 715                 720 


Gly Leu Gln Val Lys Ala Ala Ser Val Pro Val Lys Gly Ser Leu Gly 
                725                 730                 735     


Gln Gly Thr Ala Pro Val Leu Pro Gly Lys Thr Gly Pro Thr Val Thr 
            740                 745                 750         


Gln Val Lys Ala Glu Lys Gln Glu Asp Ser Glu Ser Ser Glu Glu Glu 
        755                 760                 765             


Ser Asp Ser Glu Glu Ala Ala Ala Ser Pro Ala Gln Val Lys Thr Ser 
    770                 775                 780                 


Val Lys Lys Thr Gln Ala Lys Ala Asn Pro Ala Ala Ala Arg Ala Pro 
785                 790                 795                 800 


Ser Ala Lys Gly Thr Ile Ser Ala Pro Gly Lys Val Val Thr Ala Ala 
                805                 810                 815     


Ala Gln Ala Lys Gln Arg Ser Pro Ser Lys Val Lys Pro Pro Val Arg 
            820                 825                 830         


Asn Pro Gln Asn Ser Thr Val Leu Ala Arg Gly Pro Ala Ser Val Pro 
        835                 840                 845             


Ser Val Gly Lys Ala Val Ala Thr Ala Ala Gln Ala Gln Thr Gly Pro 
    850                 855                 860                 


Glu Glu Asp Ser Gly Ser Ser Glu Glu Glu Ser Asp Ser Glu Glu Glu 
865                 870                 875                 880 


Ala Glu Thr Leu Ala Gln Val Lys Pro Ser Gly Lys Thr His Gln Ile 
                885                 890                 895     


Arg Ala Ala Leu Ala Pro Ala Lys Glu Ser Pro Arg Lys Gly Ala Ala 
            900                 905                 910         


Pro Thr Pro Pro Gly Lys Thr Gly Pro Ser Ala Ala Gln Ala Gly Lys 
        915                 920                 925             


Gln Asp Asp Ser Gly Ser Ser Ser Glu Glu Ser Asp Ser Asp Gly Glu 
    930                 935                 940                 


Ala Pro Ala Ala Val Thr Ser Ala Gln Asp Gln Glu Ser Ser 
945                 950                 955             


<210>  1406
<211>  235
<212>  PRT
<213>  Human

<400>  1406

Met Asp Pro Ala Arg Pro Leu Gly Leu Ser Ile Leu Leu Leu Phe Leu 
1               5                   10                  15      


Thr Glu Ala Ala Leu Gly Asp Ala Ala Gln Glu Pro Thr Gly Asn Asn 
            20                  25                  30          


Ala Glu Ile Cys Leu Leu Pro Leu Asp Tyr Gly Pro Cys Arg Ala Leu 
        35                  40                  45              


Leu Leu Arg Tyr Tyr Tyr Asp Arg Tyr Thr Gln Ser Cys Arg Gln Phe 
    50                  55                  60                  


Leu Tyr Gly Gly Cys Glu Gly Asn Ala Asn Asn Phe Tyr Thr Trp Glu 
65                  70                  75                  80  


Ala Cys Asp Asp Ala Cys Trp Arg Ile Glu Lys Val Pro Lys Val Cys 
                85                  90                  95      


Arg Leu Gln Val Ser Val Asp Asp Gln Cys Glu Gly Ser Thr Glu Lys 
            100                 105                 110         


Tyr Phe Phe Asn Leu Ser Ser Met Thr Cys Glu Lys Phe Phe Ser Gly 
        115                 120                 125             


Gly Cys His Arg Asn Arg Ile Glu Asn Arg Phe Pro Asp Glu Ala Thr 
    130                 135                 140                 


Cys Met Gly Phe Cys Ala Pro Lys Lys Ile Pro Ser Phe Cys Tyr Ser 
145                 150                 155                 160 


Pro Lys Asp Glu Gly Leu Cys Ser Ala Asn Val Thr Arg Tyr Tyr Phe 
                165                 170                 175     


Asn Pro Arg Tyr Arg Thr Cys Asp Ala Phe Thr Tyr Thr Gly Cys Gly 
            180                 185                 190         


Gly Asn Asp Asn Asn Phe Val Ser Arg Glu Asp Cys Lys Arg Ala Cys 
        195                 200                 205             


Ala Lys Ala Leu Lys Lys Lys Lys Lys Met Pro Lys Leu Arg Phe Ala 
    210                 215                 220                 


Ser Arg Ile Arg Lys Ile Arg Lys Lys Gln Phe 
225                 230                 235 


<210>  1407
<211>  198
<212>  PRT
<213>  Human

<400>  1407

Met Ala Thr Leu Trp Gly Gly Leu Leu Arg Leu Gly Ser Leu Leu Ser 
1               5                   10                  15      


Leu Ser Cys Leu Ala Leu Ser Val Leu Leu Leu Ala Gln Leu Ser Asp 
            20                  25                  30          


Ala Ala Lys Asn Phe Glu Asp Val Arg Cys Lys Cys Ile Cys Pro Pro 
        35                  40                  45              


Tyr Lys Glu Asn Ser Gly His Ile Tyr Asn Lys Asn Ile Ser Gln Lys 
    50                  55                  60                  


Asp Cys Asp Cys Leu His Val Val Glu Pro Met Pro Val Arg Gly Pro 
65                  70                  75                  80  


Asp Val Glu Ala Tyr Cys Leu Arg Cys Glu Cys Lys Tyr Glu Glu Arg 
                85                  90                  95      


Ser Ser Val Thr Ile Lys Val Thr Ile Ile Ile Tyr Leu Ser Ile Leu 
            100                 105                 110         


Gly Leu Leu Leu Leu Tyr Met Val Tyr Leu Thr Leu Val Glu Pro Ile 
        115                 120                 125             


Leu Lys Arg Arg Leu Phe Gly His Ala Gln Leu Ile Gln Ser Asp Asp 
    130                 135                 140                 


Asp Ile Gly Asp His Gln Pro Phe Ala Asn Ala His Asp Val Leu Ala 
145                 150                 155                 160 


Arg Ser Arg Ser Arg Ala Asn Val Leu Asn Lys Val Glu Tyr Ala Gln 
                165                 170                 175     


Gln Arg Trp Lys Leu Gln Val Gln Glu Gln Arg Lys Ser Val Phe Asp 
            180                 185                 190         


Arg His Val Val Leu Ser 
        195             


<210>  1408
<211>  465
<212>  PRT
<213>  Human

<400>  1408

Met Lys Glu Pro Asp Ala Ile Lys Leu Phe Val Gly Gln Ile Pro Arg 
1               5                   10                  15      


His Leu Glu Glu Lys Asp Leu Lys Pro Ile Phe Glu Gln Phe Gly Arg 
            20                  25                  30          


Ile Phe Glu Leu Thr Val Ile Lys Asp Lys Tyr Thr Gly Leu His Lys 
        35                  40                  45              


Gly Cys Ala Phe Leu Thr Tyr Cys Ala Arg Asp Ser Ala Leu Lys Ala 
    50                  55                  60                  


Gln Ser Ala Leu His Glu Gln Lys Thr Leu Pro Gly Met Asn Arg Pro 
65                  70                  75                  80  


Ile Gln Val Lys Pro Ala Asp Ser Glu Ser Arg Gly Glu Asp Arg Lys 
                85                  90                  95      


Leu Phe Val Gly Met Leu Gly Lys Gln Gln Thr Asp Glu Asp Val Arg 
            100                 105                 110         


Lys Met Phe Glu Pro Phe Gly Thr Ile Asp Glu Cys Thr Val Leu Arg 
        115                 120                 125             


Gly Pro Asp Gly Thr Ser Lys Gly Cys Ala Phe Val Lys Phe Gln Thr 
    130                 135                 140                 


His Ala Glu Ala Gln Ala Ala Ile Asn Thr Leu His Ser Ser Arg Thr 
145                 150                 155                 160 


Leu Pro Gly Ala Ser Ser Ser Leu Val Val Lys Phe Ala Asp Thr Glu 
                165                 170                 175     


Lys Glu Arg Gly Leu Arg Arg Met Gln Gln Val Ala Thr Gln Leu Gly 
            180                 185                 190         


Met Phe Ser Pro Ile Ala Leu Gln Phe Gly Ala Tyr Ser Ala Tyr Thr 
        195                 200                 205             


Gln Ala Leu Met Gln Gln Gln Ala Ala Leu Val Ala Ala His Ser Ala 
    210                 215                 220                 


Tyr Leu Ser Pro Met Ala Thr Met Ala Ala Val Gln Met Gln His Met 
225                 230                 235                 240 


Ala Ala Ile Asn Ala Asn Gly Leu Ile Ala Thr Pro Ile Thr Pro Ser 
                245                 250                 255     


Ser Gly Thr Ser Thr Pro Pro Ala Ile Ala Ala Thr Pro Val Ser Ala 
            260                 265                 270         


Ile Pro Ala Ala Leu Gly Val Asn Gly Tyr Ser Pro Val Pro Thr Gln 
        275                 280                 285             


Pro Thr Gly Gln Pro Ala Pro Asp Ala Leu Tyr Pro Asn Gly Val His 
    290                 295                 300                 


Pro Tyr Pro Ala Gln Ser Pro Ala Ala Pro Val Asp Pro Leu Gln Gln 
305                 310                 315                 320 


Ala Tyr Ala Gly Met Gln His Tyr Thr Ala Ala Tyr Pro Ala Ala Tyr 
                325                 330                 335     


Ser Leu Val Ala Pro Ala Phe Pro Gln Pro Pro Ala Leu Val Ala Gln 
            340                 345                 350         


Gln Pro Pro Pro Pro Pro Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln 
        355                 360                 365             


Gln Gln Gln Gln Gln Arg Glu Gly Pro Asp Gly Cys Asn Ile Phe Ile 
    370                 375                 380                 


Tyr His Leu Pro Gln Glu Phe Thr Asp Ser Glu Ile Leu Gln Met Phe 
385                 390                 395                 400 


Val Pro Phe Gly His Val Ile Ser Ala Lys Val Phe Val Asp Arg Ala 
                405                 410                 415     


Thr Asn Gln Ser Lys Cys Phe Gly Phe Val Ser Phe Asp Asn Pro Ala 
            420                 425                 430         


Ser Ala Gln Ala Ala Ile Gln Ala Met Asn Gly Phe Gln Ile Gly Met 
        435                 440                 445             


Lys Arg Leu Lys Val Gln Leu Lys Arg Pro Lys Asp Ala Asn Arg Pro 
    450                 455                 460                 


Tyr 
465 


<210>  1409
<211>  835
<212>  PRT
<213>  Human

<400>  1409

Met Ala Ala Ser Ala Ala Ala Ala Ser Ala Ala Ala Ala Ser Ala Ala 
1               5                   10                  15      


Ser Gly Ser Pro Gly Pro Gly Glu Gly Ser Ala Gly Gly Glu Lys Arg 
            20                  25                  30          


Ser Thr Ala Pro Ser Ala Ala Ala Ser Ala Ser Ala Ser Ala Ala Ala 
        35                  40                  45              


Ser Ser Pro Ala Gly Gly Gly Ala Glu Ala Leu Glu Leu Leu Glu His 
    50                  55                  60                  


Cys Gly Val Cys Arg Glu Arg Leu Arg Pro Glu Arg Glu Pro Arg Leu 
65                  70                  75                  80  


Leu Pro Cys Leu His Ser Ala Cys Ser Ala Cys Leu Gly Pro Ala Ala 
                85                  90                  95      


Pro Ala Ala Ala Asn Ser Ser Gly Asp Gly Gly Ala Ala Gly Asp Gly 
            100                 105                 110         


Thr Val Val Asp Cys Pro Val Cys Lys Gln Gln Cys Phe Ser Lys Asp 
        115                 120                 125             


Ile Val Glu Asn Tyr Phe Met Arg Asp Ser Gly Ser Lys Ala Ala Thr 
    130                 135                 140                 


Asp Ala Gln Asp Ala Asn Gln Cys Cys Thr Ser Cys Glu Asp Asn Ala 
145                 150                 155                 160 


Pro Ala Thr Ser Tyr Cys Val Glu Cys Ser Glu Pro Leu Cys Glu Thr 
                165                 170                 175     


Cys Val Glu Ala His Gln Arg Val Lys Tyr Thr Lys Asp His Thr Val 
            180                 185                 190         


Arg Ser Thr Gly Pro Ala Lys Ser Arg Asp Gly Glu Arg Thr Val Tyr 
        195                 200                 205             


Cys Asn Val His Lys His Glu Pro Leu Val Leu Phe Cys Glu Ser Cys 
    210                 215                 220                 


Asp Thr Leu Thr Cys Arg Asp Cys Gln Leu Asn Ala His Lys Asp His 
225                 230                 235                 240 


Gln Tyr Gln Phe Leu Glu Asp Ala Val Arg Asn Gln Arg Lys Leu Leu 
                245                 250                 255     


Ala Ser Leu Val Lys Arg Leu Gly Asp Lys His Ala Thr Leu Gln Lys 
            260                 265                 270         


Ser Thr Lys Glu Val Arg Ser Ser Ile Arg Gln Val Ser Asp Val Gln 
        275                 280                 285             


Lys Arg Val Gln Val Asp Val Lys Met Ala Ile Leu Gln Ile Met Lys 
    290                 295                 300                 


Glu Leu Asn Lys Arg Gly Arg Val Leu Val Asn Asp Ala Gln Lys Val 
305                 310                 315                 320 


Thr Glu Gly Gln Gln Glu Arg Leu Glu Arg Gln His Trp Thr Met Thr 
                325                 330                 335     


Lys Ile Gln Lys His Gln Glu His Ile Leu Arg Phe Ala Ser Trp Ala 
            340                 345                 350         


Leu Glu Ser Asp Asn Asn Thr Ala Leu Leu Leu Ser Lys Lys Leu Ile 
        355                 360                 365             


Tyr Phe Gln Leu His Arg Ala Leu Lys Met Ile Val Asp Pro Val Glu 
    370                 375                 380                 


Pro His Gly Glu Met Lys Phe Gln Trp Asp Leu Asn Ala Trp Thr Lys 
385                 390                 395                 400 


Ser Ala Glu Ala Phe Gly Lys Ile Val Ala Glu Arg Pro Gly Thr Asn 
                405                 410                 415     


Ser Thr Gly Pro Ala Pro Met Ala Pro Pro Arg Ala Pro Gly Pro Leu 
            420                 425                 430         


Ser Lys Gln Gly Ser Gly Ser Ser Gln Pro Met Glu Val Gln Glu Gly 
        435                 440                 445             


Tyr Gly Phe Gly Ser Gly Asp Asp Pro Tyr Ser Ser Ala Glu Pro His 
    450                 455                 460                 


Val Ser Gly Val Lys Arg Ser Arg Ser Gly Glu Gly Glu Val Ser Gly 
465                 470                 475                 480 


Leu Met Arg Lys Val Pro Arg Val Ser Leu Glu Arg Leu Asp Leu Asp 
                485                 490                 495     


Leu Thr Ala Asp Ser Gln Pro Pro Val Phe Lys Val Phe Pro Gly Ser 
            500                 505                 510         


Thr Thr Glu Asp Tyr Asn Leu Ile Val Ile Glu Arg Gly Ala Ala Ala 
        515                 520                 525             


Ala Ala Thr Gly Gln Pro Gly Thr Ala Pro Ala Gly Thr Pro Gly Ala 
    530                 535                 540                 


Pro Pro Leu Ala Gly Met Ala Ile Val Lys Glu Glu Glu Thr Glu Ala 
545                 550                 555                 560 


Ala Ile Gly Ala Pro Pro Thr Ala Thr Glu Gly Pro Glu Thr Lys Pro 
                565                 570                 575     


Val Leu Met Ala Leu Ala Glu Gly Pro Gly Ala Glu Gly Pro Arg Leu 
            580                 585                 590         


Ala Ser Pro Ser Gly Ser Thr Ser Ser Gly Leu Glu Val Val Ala Pro 
        595                 600                 605             


Glu Gly Thr Ser Ala Pro Gly Gly Gly Pro Gly Thr Leu Asp Asp Ser 
    610                 615                 620                 


Ala Thr Ile Cys Arg Val Cys Gln Lys Pro Gly Asp Leu Val Met Cys 
625                 630                 635                 640 


Asn Gln Cys Glu Phe Cys Phe His Leu Asp Cys His Leu Pro Ala Leu 
                645                 650                 655     


Gln Asp Val Pro Gly Glu Glu Trp Ser Cys Ser Leu Cys His Val Leu 
            660                 665                 670         


Pro Asp Leu Lys Glu Glu Asp Gly Ser Leu Ser Leu Asp Gly Ala Asp 
        675                 680                 685             


Ser Thr Gly Val Val Ala Lys Leu Ser Pro Ala Asn Gln Arg Lys Cys 
    690                 695                 700                 


Glu Arg Val Leu Leu Ala Leu Phe Cys His Glu Pro Cys Arg Pro Leu 
705                 710                 715                 720 


His Gln Leu Ala Thr Asp Ser Thr Phe Ser Leu Asp Gln Pro Gly Gly 
                725                 730                 735     


Thr Leu Asp Leu Thr Leu Ile Arg Ala Arg Leu Gln Glu Lys Leu Ser 
            740                 745                 750         


Pro Pro Tyr Ser Ser Pro Gln Glu Phe Ala Gln Asp Val Gly Arg Met 
        755                 760                 765             


Phe Lys Gln Phe Asn Lys Leu Thr Glu Asp Lys Ala Asp Val Gln Ser 
    770                 775                 780                 


Ile Ile Gly Leu Gln Arg Phe Phe Glu Thr Arg Met Asn Glu Ala Phe 
785                 790                 795                 800 


Gly Asp Thr Lys Phe Ser Ala Val Leu Val Glu Pro Pro Pro Met Ser 
                805                 810                 815     


Leu Pro Gly Ala Gly Leu Ser Ser Gln Glu Leu Ser Gly Gly Pro Gly 
            820                 825                 830         


Asp Gly Pro 
        835 


<210>  1410
<211>  3097
<212>  PRT
<213>  Human

<400>  1410

Met Ser Gly Ser Ser Gly Gly Ala Ala Ala Pro Ala Ala Ser Ser Gly 
1               5                   10                  15      


Pro Ala Ala Ala Ala Ser Ala Ala Gly Ser Gly Cys Gly Gly Gly Ala 
            20                  25                  30          


Gly Glu Gly Ala Glu Glu Ala Ala Lys Asp Leu Ala Asp Ile Ala Ala 
        35                  40                  45              


Phe Phe Arg Ser Gly Phe Arg Lys Asn Asp Glu Met Lys Ala Met Asp 
    50                  55                  60                  


Val Leu Pro Ile Leu Lys Glu Lys Val Ala Tyr Leu Ser Gly Gly Arg 
65                  70                  75                  80  


Asp Lys Arg Gly Gly Pro Ile Leu Thr Phe Pro Ala Arg Ser Asn His 
                85                  90                  95      


Asp Arg Ile Arg Gln Glu Asp Leu Arg Arg Leu Ile Ser Tyr Leu Ala 
            100                 105                 110         


Cys Ile Pro Ser Glu Glu Val Cys Lys Arg Gly Phe Thr Val Ile Val 
        115                 120                 125             


Asp Met Arg Gly Ser Lys Trp Asp Ser Ile Lys Pro Leu Leu Lys Ile 
    130                 135                 140                 


Leu Gln Glu Ser Phe Pro Cys Cys Ile His Val Ala Leu Ile Ile Lys 
145                 150                 155                 160 


Pro Asp Asn Phe Trp Gln Lys Gln Arg Thr Asn Phe Gly Ser Ser Lys 
                165                 170                 175     


Phe Glu Phe Glu Thr Asn Met Val Ser Leu Glu Gly Leu Thr Lys Val 
            180                 185                 190         


Val Asp Pro Ser Gln Leu Thr Pro Glu Phe Asp Gly Cys Leu Glu Tyr 
        195                 200                 205             


Asn His Glu Glu Trp Ile Glu Ile Arg Val Ala Phe Glu Asp Tyr Ile 
    210                 215                 220                 


Ser Asn Ala Thr His Met Leu Ser Arg Leu Glu Glu Leu Gln Asp Ile 
225                 230                 235                 240 


Leu Ala Lys Lys Glu Leu Pro Gln Asp Leu Glu Gly Ala Arg Asn Met 
                245                 250                 255     


Ile Glu Glu His Ser Gln Leu Lys Lys Lys Val Ile Lys Ala Pro Ile 
            260                 265                 270         


Glu Asp Leu Asp Leu Glu Gly Gln Lys Leu Leu Gln Arg Ile Gln Ser 
        275                 280                 285             


Ser Glu Ser Phe Pro Lys Lys Asn Ser Gly Ser Gly Asn Ala Asp Leu 
    290                 295                 300                 


Gln Asn Leu Leu Pro Lys Val Ser Thr Met Leu Asp Arg Leu His Ser 
305                 310                 315                 320 


Thr Arg Gln His Leu His Gln Met Trp His Val Arg Lys Leu Lys Leu 
                325                 330                 335     


Asp Gln Cys Phe Gln Leu Arg Leu Phe Glu Gln Asp Ala Glu Lys Met 
            340                 345                 350         


Phe Asp Trp Ile Thr His Asn Lys Gly Leu Phe Leu Asn Ser Tyr Thr 
        355                 360                 365             


Glu Ile Gly Thr Ser His Pro His Ala Met Glu Leu Gln Thr Gln His 
    370                 375                 380                 


Asn His Phe Ala Met Asn Cys Met Asn Val Tyr Val Asn Ile Asn Arg 
385                 390                 395                 400 


Ile Met Ser Val Ala Asn Arg Leu Val Glu Ser Gly His Tyr Ala Ser 
                405                 410                 415     


Gln Gln Ile Arg Gln Ile Ala Ser Gln Leu Glu Gln Glu Trp Lys Ala 
            420                 425                 430         


Phe Ala Ala Ala Leu Asp Glu Arg Ser Thr Leu Leu Asp Met Ser Ser 
        435                 440                 445             


Ile Phe His Gln Lys Ala Glu Lys Tyr Met Ser Asn Val Asp Ser Trp 
    450                 455                 460                 


Cys Lys Ala Cys Gly Glu Val Asp Leu Pro Ser Glu Leu Gln Asp Leu 
465                 470                 475                 480 


Glu Asp Ala Ile His His His Gln Gly Ile Tyr Glu His Ile Thr Leu 
                485                 490                 495     


Ala Tyr Ser Glu Val Ser Gln Asp Gly Lys Ser Leu Leu Asp Lys Leu 
            500                 505                 510         


Gln Arg Pro Leu Thr Pro Gly Ser Ser Asp Ser Leu Thr Ala Ser Ala 
        515                 520                 525             


Asn Tyr Ser Lys Ala Val His His Val Leu Asp Val Ile His Glu Val 
    530                 535                 540                 


Leu His His Gln Arg Gln Leu Glu Asn Ile Trp Gln His Arg Lys Val 
545                 550                 555                 560 


Arg Leu His Gln Arg Leu Gln Leu Cys Val Phe Gln Gln Asp Val Gln 
                565                 570                 575     


Gln Val Leu Asp Trp Ile Glu Asn His Gly Glu Ala Phe Leu Ser Lys 
            580                 585                 590         


His Thr Gly Val Gly Lys Ser Leu His Arg Ala Arg Ala Leu Gln Lys 
        595                 600                 605             


Arg His Glu Asp Phe Glu Glu Val Ala Gln Asn Thr Tyr Thr Asn Ala 
    610                 615                 620                 


Asp Lys Leu Leu Glu Ala Ala Glu Gln Leu Ala Gln Thr Gly Glu Cys 
625                 630                 635                 640 


Asp Pro Glu Glu Ile Tyr Gln Ala Ala His Gln Leu Glu Asp Arg Ile 
                645                 650                 655     


Gln Asp Phe Val Arg Arg Val Glu Gln Arg Lys Ile Leu Leu Asp Met 
            660                 665                 670         


Ser Val Ser Phe His Thr His Val Lys Glu Leu Trp Thr Trp Leu Glu 
        675                 680                 685             


Glu Leu Gln Lys Glu Leu Leu Asp Asp Val Tyr Ala Glu Ser Val Glu 
    690                 695                 700                 


Ala Val Gln Asp Leu Ile Lys Arg Phe Gly Gln Gln Gln Gln Thr Thr 
705                 710                 715                 720 


Leu Gln Val Thr Val Asn Val Ile Lys Glu Gly Glu Asp Leu Ile Gln 
                725                 730                 735     


Gln Leu Arg Asp Ser Ala Ile Ser Ser Asn Lys Thr Pro His Asn Ser 
            740                 745                 750         


Ser Ile Asn His Ile Glu Thr Val Leu Gln Gln Leu Asp Glu Ala Gln 
        755                 760                 765             


Ser Gln Met Glu Glu Leu Phe Gln Glu Arg Lys Ile Lys Leu Glu Leu 
    770                 775                 780                 


Phe Leu Gln Leu Arg Ile Phe Glu Arg Asp Ala Ile Asp Ile Ile Ser 
785                 790                 795                 800 


Asp Leu Glu Ser Trp Asn Asp Glu Leu Ser Gln Gln Met Asn Asp Phe 
                805                 810                 815     


Asp Thr Glu Asp Leu Thr Ile Ala Glu Gln Arg Leu Gln His His Ala 
            820                 825                 830         


Asp Lys Ala Leu Thr Met Asn Asn Leu Thr Phe Asp Val Ile His Gln 
        835                 840                 845             


Gly Gln Asp Leu Leu Gln Tyr Val Asn Glu Val Gln Ala Ser Gly Val 
    850                 855                 860                 


Glu Leu Leu Cys Asp Arg Asp Val Asp Met Ala Thr Arg Val Gln Asp 
865                 870                 875                 880 


Leu Leu Glu Phe Leu His Glu Lys Gln Gln Glu Leu Asp Leu Ala Ala 
                885                 890                 895     


Glu Gln His Arg Lys His Leu Glu Gln Cys Val Gln Leu Arg His Leu 
            900                 905                 910         


Gln Ala Glu Val Lys Gln Val Leu Gly Trp Ile Arg Asn Gly Glu Ser 
        915                 920                 925             


Met Leu Asn Ala Gly Leu Ile Thr Ala Ser Ser Leu Gln Glu Ala Glu 
    930                 935                 940                 


Gln Leu Gln Arg Glu His Glu Gln Phe Gln His Ala Ile Glu Lys Thr 
945                 950                 955                 960 


His Gln Ser Ala Leu Gln Val Gln Gln Lys Ala Glu Ala Met Leu Gln 
                965                 970                 975     


Ala Asn His Tyr Asp Met Asp Met Ile Arg Asp Cys Ala Glu Lys Val 
            980                 985                 990         


Ala Ser His Trp Gln Gln Leu Met  Leu Lys Met Glu Asp  Arg Leu Lys 
        995                 1000                 1005             


Leu Val  Asn Ala Ser Val Ala  Phe Tyr Lys Thr Ser  Glu Gln Val 
    1010                 1015                 1020             


Cys Ser  Val Leu Glu Ser Leu  Glu Gln Glu Tyr Lys  Arg Glu Glu 
    1025                 1030                 1035             


Asp Trp  Cys Gly Gly Ala Asp  Lys Leu Gly Pro Asn  Ser Glu Thr 
    1040                 1045                 1050             


Asp His  Val Thr Pro Met Ile  Ser Lys His Leu Glu  Gln Lys Glu 
    1055                 1060                 1065             


Ala Phe  Leu Lys Ala Cys Thr  Leu Ala Arg Arg Asn  Ala Asp Val 
    1070                 1075                 1080             


Phe Leu  Lys Tyr Leu His Arg  Asn Ser Val Asn Met  Pro Gly Met 
    1085                 1090                 1095             


Val Thr  His Ile Lys Ala Pro  Glu Gln Gln Val Lys  Asn Ile Leu 
    1100                 1105                 1110             


Asn Glu  Leu Phe Gln Arg Glu  Asn Arg Val Leu His  Tyr Trp Thr 
    1115                 1120                 1125             


Met Arg  Lys Arg Arg Leu Asp  Gln Cys Gln Gln Tyr  Val Val Phe 
    1130                 1135                 1140             


Glu Arg  Ser Ala Lys Gln Ala  Leu Glu Trp Ile His  Asp Asn Gly 
    1145                 1150                 1155             


Glu Phe  Tyr Leu Ser Thr His  Thr Ser Thr Gly Ser  Ser Ile Gln 
    1160                 1165                 1170             


His Thr  Gln Glu Leu Leu Lys  Glu His Glu Glu Phe  Gln Ile Thr 
    1175                 1180                 1185             


Ala Lys  Gln Thr Lys Glu Arg  Val Lys Leu Leu Ile  Gln Leu Ala 
    1190                 1195                 1200             


Asp Gly  Phe Cys Glu Lys Gly  His Ala His Ala Ala  Glu Ile Lys 
    1205                 1210                 1215             


Lys Cys  Val Thr Ala Val Asp  Lys Arg Tyr Arg Asp  Phe Ser Leu 
    1220                 1225                 1230             


Arg Met  Glu Lys Tyr Arg Thr  Ser Leu Glu Lys Ala  Leu Gly Ile 
    1235                 1240                 1245             


Ser Ser  Asp Ser Asn Lys Ser  Ser Lys Ser Leu Gln  Leu Asp Ile 
    1250                 1255                 1260             


Ile Pro  Ala Ser Ile Pro Gly  Ser Glu Val Lys Leu  Arg Asp Ala 
    1265                 1270                 1275             


Ala His  Glu Leu Asn Glu Glu  Lys Arg Lys Ser Ala  Arg Arg Lys 
    1280                 1285                 1290             


Glu Phe  Ile Met Ala Glu Leu  Ile Gln Thr Glu Lys  Ala Tyr Val 
    1295                 1300                 1305             


Arg Asp  Leu Arg Glu Cys Met  Asp Thr Tyr Leu Trp  Glu Met Thr 
    1310                 1315                 1320             


Ser Gly  Val Glu Glu Ile Pro  Pro Gly Ile Val Asn  Lys Glu Leu 
    1325                 1330                 1335             


Ile Ile  Phe Gly Asn Met Gln  Glu Ile Tyr Glu Phe  His Asn Asn 
    1340                 1345                 1350             


Ile Phe  Leu Lys Glu Leu Glu  Lys Tyr Glu Gln Leu  Pro Glu Asp 
    1355                 1360                 1365             


Val Gly  His Cys Phe Val Thr  Trp Ala Asp Lys Phe  Gln Met Tyr 
    1370                 1375                 1380             


Val Thr  Tyr Cys Lys Asn Lys  Pro Asp Ser Thr Gln  Leu Ile Leu 
    1385                 1390                 1395             


Glu His  Ala Gly Ser Tyr Phe  Asp Glu Ile Gln Gln  Arg His Gly 
    1400                 1405                 1410             


Leu Ala  Asn Ser Ile Ser Ser  Tyr Leu Ile Lys Pro  Val Gln Arg 
    1415                 1420                 1425             


Ile Thr  Lys Tyr Gln Leu Leu  Leu Lys Glu Leu Leu  Thr Cys Cys 
    1430                 1435                 1440             


Glu Glu  Gly Lys Gly Glu Ile  Lys Asp Gly Leu Glu  Val Met Leu 
    1445                 1450                 1455             


Ser Val  Pro Lys Arg Ala Asn  Asp Ala Met His Leu  Ser Met Leu 
    1460                 1465                 1470             


Glu Gly  Phe Asp Glu Asn Ile  Glu Ser Gln Gly Glu  Leu Ile Leu 
    1475                 1480                 1485             


Gln Glu  Ser Phe Gln Val Trp  Asp Pro Lys Thr Leu  Ile Arg Lys 
    1490                 1495                 1500             


Gly Arg  Glu Arg His Leu Phe  Leu Phe Glu Met Ser  Leu Val Phe 
    1505                 1510                 1515             


Ser Lys  Glu Val Lys Asp Ser  Ser Gly Arg Ser Lys  Tyr Leu Tyr 
    1520                 1525                 1530             


Lys Ser  Lys Leu Phe Thr Ser  Glu Leu Gly Val Thr  Glu His Val 
    1535                 1540                 1545             


Glu Gly  Asp Pro Cys Lys Phe  Ala Leu Trp Val Gly  Arg Thr Pro 
    1550                 1555                 1560             


Thr Ser  Asp Asn Lys Ile Val  Leu Lys Ala Ser Ser  Ile Glu Asn 
    1565                 1570                 1575             


Lys Gln  Asp Trp Ile Lys His  Ile Arg Glu Val Ile  Gln Glu Arg 
    1580                 1585                 1590             


Thr Ile  His Leu Lys Gly Ala  Leu Lys Glu Pro Ile  His Ile Pro 
    1595                 1600                 1605             


Lys Thr  Ala Pro Ala Thr Arg  Gln Lys Gly Arg Arg  Asp Gly Glu 
    1610                 1615                 1620             


Asp Leu  Asp Ser Gln Gly Asp  Gly Ser Ser Gln Pro  Asp Thr Ile 
    1625                 1630                 1635             


Ser Ile  Ala Ser Arg Thr Ser  Gln Asn Thr Leu Asp  Ser Asp Lys 
    1640                 1645                 1650             


Leu Ser  Gly Gly Cys Glu Leu  Thr Val Val Ile His  Asp Phe Thr 
    1655                 1660                 1665             


Ala Cys  Asn Ser Asn Glu Leu  Thr Ile Arg Arg Gly  Gln Thr Val 
    1670                 1675                 1680             


Glu Val  Leu Glu Arg Pro His  Asp Lys Pro Asp Trp  Cys Leu Val 
    1685                 1690                 1695             


Arg Thr  Thr Asp Arg Ser Pro  Ala Ala Glu Gly Leu  Val Pro Cys 
    1700                 1705                 1710             


Gly Ser  Leu Cys Ile Ala His  Ser Arg Ser Ser Met  Glu Met Glu 
    1715                 1720                 1725             


Gly Ile  Phe Asn His Lys Asp  Ser Leu Ser Val Ser  Ser Asn Asp 
    1730                 1735                 1740             


Ala Ser  Pro Pro Ala Ser Val  Ala Ser Leu Gln Pro  His Met Ile 
    1745                 1750                 1755             


Gly Ala  Gln Ser Ser Pro Gly  Pro Lys Arg Pro Gly  Asn Thr Leu 
    1760                 1765                 1770             


Arg Lys  Trp Leu Thr Ser Pro  Val Arg Arg Leu Ser  Ser Gly Lys 
    1775                 1780                 1785             


Ala Asp  Gly His Val Lys Lys  Leu Ala His Lys His  Lys Lys Ser 
    1790                 1795                 1800             


Arg Glu  Val Arg Lys Ser Ala  Asp Ala Gly Ser Gln  Lys Asp Ser 
    1805                 1810                 1815             


Asp Asp  Ser Ala Ala Thr Pro  Gln Asp Glu Thr Val  Glu Glu Arg 
    1820                 1825                 1830             


Gly Arg  Asn Glu Gly Leu Ser  Ser Gly Thr Leu Ser  Lys Ser Ser 
    1835                 1840                 1845             


Ser Ser  Gly Met Gln Ser Cys  Gly Glu Glu Glu Gly  Glu Glu Gly 
    1850                 1855                 1860             


Ala Asp  Ala Val Pro Leu Pro  Pro Pro Met Ala Ile  Gln Gln His 
    1865                 1870                 1875             


Ser Leu  Leu Gln Pro Asp Ser  Gln Asp Asp Lys Ala  Ser Ser Arg 
    1880                 1885                 1890             


Leu Leu  Val Arg Pro Thr Ser  Ser Glu Thr Pro Ser  Ala Ala Glu 
    1895                 1900                 1905             


Leu Val  Ser Ala Ile Glu Glu  Leu Val Lys Ser Lys  Met Ala Leu 
    1910                 1915                 1920             


Glu Asp  Arg Pro Ser Ser Leu  Leu Val Asp Gln Gly  Asp Ser Ser 
    1925                 1930                 1935             


Ser Pro  Ser Phe Asn Pro Ser  Asp Asn Ser Leu Leu  Ser Ser Ser 
    1940                 1945                 1950             


Ser Pro  Ile Asp Glu Met Glu  Glu Arg Lys Ser Ser  Ser Leu Lys 
    1955                 1960                 1965             


Arg Arg  His Tyr Val Leu Gln  Glu Leu Val Glu Thr  Glu Arg Asp 
    1970                 1975                 1980             


Tyr Val  Arg Asp Leu Gly Tyr  Val Val Glu Gly Tyr  Met Ala Leu 
    1985                 1990                 1995             


Met Lys  Glu Asp Gly Val Pro  Asp Asp Met Lys Gly  Lys Asp Lys 
    2000                 2005                 2010             


Ile Val  Phe Gly Asn Ile His  Gln Ile Tyr Asp Trp  His Arg Asp 
    2015                 2020                 2025             


Phe Phe  Leu Gly Glu Leu Glu  Lys Cys Leu Glu Asp  Pro Glu Lys 
    2030                 2035                 2040             


Leu Gly  Ser Leu Phe Val Lys  His Glu Arg Arg Leu  His Met Tyr 
    2045                 2050                 2055             


Ile Ala  Tyr Cys Gln Asn Lys  Pro Lys Ser Glu His  Ile Val Ser 
    2060                 2065                 2070             


Glu Tyr  Ile Asp Thr Phe Phe  Glu Asp Leu Lys Gln  Arg Leu Gly 
    2075                 2080                 2085             


His Arg  Leu Gln Leu Thr Asp  Leu Leu Ile Lys Pro  Val Gln Arg 
    2090                 2095                 2100             


Ile Met  Lys Tyr Gln Leu Leu  Leu Lys Asp Phe Leu  Lys Tyr Ser 
    2105                 2110                 2115             


Lys Lys  Ala Ser Leu Asp Thr  Ser Glu Leu Glu Arg  Ala Val Glu 
    2120                 2125                 2130             


Val Met  Cys Ile Val Pro Arg  Arg Cys Asn Asp Met  Met Asn Val 
    2135                 2140                 2145             


Gly Arg  Leu Gln Gly Phe Asp  Gly Lys Ile Val Ala  Gln Gly Lys 
    2150                 2155                 2160             


Leu Leu  Leu Gln Asp Thr Phe  Leu Val Thr Asp Gln  Asp Ala Gly 
    2165                 2170                 2175             


Leu Leu  Pro Arg Cys Arg Glu  Arg Arg Ile Phe Leu  Phe Glu Gln 
    2180                 2185                 2190             


Ile Val  Ile Phe Ser Glu Pro  Leu Asp Lys Lys Lys  Gly Phe Ser 
    2195                 2200                 2205             


Met Pro  Gly Phe Leu Phe Lys  Asn Ser Ile Lys Val  Ser Cys Leu 
    2210                 2215                 2220             


Cys Leu  Glu Glu Asn Val Glu  Asn Asp Pro Cys Lys  Phe Ala Leu 
    2225                 2230                 2235             


Thr Ser  Arg Thr Gly Asp Val  Val Glu Thr Phe Ile  Leu His Ser 
    2240                 2245                 2250             


Ser Ser  Pro Ser Val Arg Gln  Thr Trp Ile His Glu  Ile Asn Gln 
    2255                 2260                 2265             


Ile Leu  Glu Asn Gln Arg Asn  Phe Leu Asn Ala Leu  Thr Ser Pro 
    2270                 2275                 2280             


Ile Glu  Tyr Gln Arg Asn His  Ser Gly Gly Gly Gly  Gly Gly Gly 
    2285                 2290                 2295             


Ser Gly  Gly Ser Gly Gly Gly  Gly Gly Ser Gly Gly  Gly Gly Ala 
    2300                 2305                 2310             


Pro Ser  Gly Gly Ser Gly His  Ser Gly Gly Pro Ser  Ser Cys Gly 
    2315                 2320                 2325             


Gly Ala  Pro Ser Thr Ser Arg  Ser Arg Pro Ser Arg  Ile Pro Gln 
    2330                 2335                 2340             


Pro Val  Arg His His Pro Pro  Val Leu Val Ser Ser  Ala Ala Ser 
    2345                 2350                 2355             


Ser Gln  Ala Glu Ala Asp Lys  Met Ser Gly Thr Ser  Thr Pro Gly 
    2360                 2365                 2370             


Pro Ser  Leu Pro Pro Pro Gly  Ala Ala Pro Glu Ala  Gly Pro Ser 
    2375                 2380                 2385             


Ala Pro  Ser Arg Arg Pro Pro  Gly Ala Asp Ala Glu  Gly Ser Glu 
    2390                 2395                 2400             


Arg Glu  Ala Glu Pro Ile Pro  Lys Met Lys Val Leu  Glu Ser Pro 
    2405                 2410                 2415             


Arg Lys  Gly Ala Ala Asn Ala  Ser Gly Ser Ser Pro  Asp Ala Pro 
    2420                 2425                 2430             


Ala Lys  Asp Ala Arg Ala Ser  Leu Gly Thr Leu Pro  Leu Gly Lys 
    2435                 2440                 2445             


Pro Arg  Ala Gly Ala Ala Ser  Pro Leu Asn Ser Pro  Leu Ser Ser 
    2450                 2455                 2460             


Ala Val  Pro Ser Leu Gly Lys  Glu Pro Phe Pro Pro  Ser Ser Pro 
    2465                 2470                 2475             


Leu Gln  Lys Gly Gly Ser Phe  Trp Ser Ser Ile Pro  Ala Ser Pro 
    2480                 2485                 2490             


Ala Ser  Arg Pro Gly Ser Phe  Thr Phe Pro Gly Asp  Ser Asp Ser 
    2495                 2500                 2505             


Leu Gln  Arg Gln Thr Pro Arg  His Ala Ala Pro Gly  Lys Asp Thr 
    2510                 2515                 2520             


Asp Arg  Met Ser Thr Cys Ser  Ser Ala Ser Glu Gln  Ser Val Gln 
    2525                 2530                 2535             


Ser Thr  Gln Ser Asn Gly Ser  Glu Ser Ser Ser Ser  Ser Asn Ile 
    2540                 2545                 2550             


Ser Thr  Met Leu Val Thr His  Asp Tyr Thr Ala Val  Lys Glu Asp 
    2555                 2560                 2565             


Glu Ile  Asn Val Tyr Gln Gly  Glu Val Val Gln Ile  Leu Ala Ser 
    2570                 2575                 2580             


Asn Gln  Gln Asn Met Phe Leu  Val Phe Arg Ala Ala  Thr Asp Gln 
    2585                 2590                 2595             


Cys Pro  Ala Ala Glu Gly Trp  Ile Pro Gly Phe Val  Leu Gly His 
    2600                 2605                 2610             


Thr Ser  Ala Val Ile Val Glu  Asn Pro Asp Gly Thr  Leu Lys Lys 
    2615                 2620                 2625             


Ser Thr  Ser Trp His Thr Ala  Leu Arg Leu Arg Lys  Lys Ser Glu 
    2630                 2635                 2640             


Lys Lys  Asp Lys Asp Gly Lys  Arg Glu Gly Lys Leu  Glu Asn Gly 
    2645                 2650                 2655             


Tyr Arg  Lys Ser Arg Glu Gly  Leu Ser Asn Lys Val  Ser Val Lys 
    2660                 2665                 2670             


Leu Leu  Asn Pro Asn Tyr Ile  Tyr Asp Val Pro Pro  Glu Phe Val 
    2675                 2680                 2685             


Ile Pro  Leu Ser Glu Val Thr  Cys Glu Thr Gly Glu  Thr Val Val 
    2690                 2695                 2700             


Leu Arg  Cys Arg Val Cys Gly  Arg Pro Lys Ala Ser  Ile Thr Trp 
    2705                 2710                 2715             


Lys Gly  Pro Glu His Asn Thr  Leu Asn Asn Asp Gly  His Tyr Ser 
    2720                 2725                 2730             


Ile Ser  Tyr Ser Asp Leu Gly  Glu Ala Thr Leu Lys  Ile Val Gly 
    2735                 2740                 2745             


Val Thr  Thr Glu Asp Asp Gly  Ile Tyr Thr Cys Ile  Ala Val Asn 
    2750                 2755                 2760             


Asp Met  Gly Ser Ala Ser Ser  Ser Ala Ser Leu Arg  Val Leu Gly 
    2765                 2770                 2775             


Pro Gly  Met Asp Gly Ile Met  Val Thr Trp Lys Asp  Asn Phe Asp 
    2780                 2785                 2790             


Ser Phe  Tyr Ser Glu Val Ala  Glu Leu Gly Arg Gly  Arg Phe Ser 
    2795                 2800                 2805             


Val Val  Lys Lys Cys Asp Gln  Lys Gly Thr Lys Arg  Ala Val Ala 
    2810                 2815                 2820             


Thr Lys  Phe Val Asn Lys Lys  Leu Met Lys Arg Asp  Gln Val Thr 
    2825                 2830                 2835             


His Glu  Leu Gly Ile Leu Gln  Ser Leu Gln His Pro  Leu Leu Val 
    2840                 2845                 2850             


Gly Leu  Leu Asp Thr Phe Glu  Thr Pro Thr Ser Tyr  Ile Leu Val 
    2855                 2860                 2865             


Leu Glu  Met Ala Asp Gln Gly  Arg Leu Leu Asp Cys  Val Val Arg 
    2870                 2875                 2880             


Trp Gly  Ser Leu Thr Glu Gly  Lys Ile Arg Ala His  Leu Gly Glu 
    2885                 2890                 2895             


Val Leu  Glu Ala Val Arg Tyr  Leu His Asn Cys Arg  Ile Ala His 
    2900                 2905                 2910             


Leu Asp  Leu Lys Pro Glu Asn  Ile Leu Val Asp Glu  Ser Leu Ala 
    2915                 2920                 2925             


Lys Pro  Thr Ile Lys Leu Ala  Asp Phe Gly Asp Ala  Val Gln Leu 
    2930                 2935                 2940             


Asn Thr  Thr Tyr Tyr Ile His  Gln Leu Leu Gly Asn  Pro Glu Phe 
    2945                 2950                 2955             


Ala Ala  Pro Glu Ile Ile Leu  Gly Asn Pro Val Ser  Leu Thr Ser 
    2960                 2965                 2970             


Asp Thr  Trp Ser Val Gly Val  Leu Thr Tyr Val Leu  Leu Ser Gly 
    2975                 2980                 2985             


Val Ser  Pro Phe Leu Asp Asp  Ser Val Glu Glu Thr  Cys Leu Asn 
    2990                 2995                 3000             


Ile Cys  Arg Leu Asp Phe Ser  Phe Pro Asp Asp Tyr  Phe Lys Gly 
    3005                 3010                 3015             


Val Ser  Gln Lys Ala Lys Glu  Phe Val Cys Phe Leu  Leu Gln Glu 
    3020                 3025                 3030             


Asp Pro  Ala Lys Arg Pro Ser  Ala Ala Leu Ala Leu  Gln Glu Gln 
    3035                 3040                 3045             


Trp Leu  Gln Ala Gly Asn Gly  Arg Ser Thr Gly Val  Leu Asp Thr 
    3050                 3055                 3060             


Ser Arg  Leu Thr Ser Phe Ile  Glu Arg Arg Lys His  Gln Asn Asp 
    3065                 3070                 3075             


Val Arg  Pro Ile Arg Ser Ile  Lys Asn Phe Leu Gln  Ser Arg Leu 
    3080                 3085                 3090             


Leu Pro  Arg Val 
    3095         


<210>  1411
<211>  444
<212>  PRT
<213>  Human

<400>  1411

Met Arg Glu Ile Val His Ile Gln Ala Gly Gln Cys Gly Asn Gln Ile 
1               5                   10                  15      


Gly Ala Lys Phe Trp Glu Val Ile Ser Asp Glu His Gly Ile Asp Pro 
            20                  25                  30          


Thr Gly Thr Tyr His Gly Asp Ser Asp Leu Gln Leu Asp Arg Ile Ser 
        35                  40                  45              


Val Tyr Tyr Asn Glu Ala Thr Gly Gly Lys Tyr Val Pro Arg Ala Ile 
    50                  55                  60                  


Leu Val Asp Leu Glu Pro Gly Thr Met Asp Ser Val Arg Ser Gly Pro 
65                  70                  75                  80  


Phe Gly Gln Ile Phe Arg Pro Asp Asn Phe Val Phe Gly Gln Ser Gly 
                85                  90                  95      


Ala Gly Asn Asn Trp Ala Lys Gly His Tyr Thr Glu Gly Ala Glu Leu 
            100                 105                 110         


Val Asp Ser Val Leu Asp Val Val Arg Lys Glu Ala Glu Ser Cys Asp 
        115                 120                 125             


Cys Leu Gln Gly Phe Gln Leu Thr His Ser Leu Gly Gly Gly Thr Gly 
    130                 135                 140                 


Ser Gly Met Gly Thr Leu Leu Ile Ser Lys Ile Arg Glu Glu Tyr Pro 
145                 150                 155                 160 


Asp Arg Ile Met Asn Thr Phe Ser Val Val Pro Ser Pro Lys Val Ser 
                165                 170                 175     


Asp Thr Val Val Glu Pro Tyr Asn Ala Thr Leu Ser Val His Gln Leu 
            180                 185                 190         


Val Glu Asn Thr Asp Glu Thr Tyr Cys Ile Asp Asn Glu Ala Leu Tyr 
        195                 200                 205             


Asp Ile Cys Phe Arg Thr Leu Lys Leu Thr Thr Pro Thr Tyr Gly Asp 
    210                 215                 220                 


Leu Asn His Leu Val Ser Ala Thr Met Ser Gly Val Thr Thr Cys Leu 
225                 230                 235                 240 


Arg Phe Pro Gly Gln Leu Asn Ala Asp Leu Arg Lys Leu Ala Val Asn 
                245                 250                 255     


Met Val Pro Phe Pro Arg Leu His Phe Phe Met Pro Gly Phe Ala Pro 
            260                 265                 270         


Leu Thr Ser Arg Gly Ser Gln Gln Tyr Arg Ala Leu Thr Val Pro Glu 
        275                 280                 285             


Leu Thr Gln Gln Val Phe Asp Ala Lys Asn Met Met Ala Ala Cys Asp 
    290                 295                 300                 


Pro Arg His Gly Arg Tyr Leu Thr Val Ala Ala Val Phe Arg Gly Arg 
305                 310                 315                 320 


Met Ser Met Lys Glu Val Asp Glu Gln Met Leu Asn Val Gln Asn Lys 
                325                 330                 335     


Asn Ser Ser Tyr Phe Val Glu Trp Ile Pro Asn Asn Val Lys Thr Ala 
            340                 345                 350         


Val Cys Asp Ile Pro Pro Arg Gly Leu Lys Met Ala Val Thr Phe Ile 
        355                 360                 365             


Gly Asn Ser Thr Ala Ile Gln Glu Leu Phe Lys Arg Ile Ser Glu Gln 
    370                 375                 380                 


Phe Thr Ala Met Phe Arg Arg Lys Ala Phe Leu His Trp Tyr Thr Gly 
385                 390                 395                 400 


Glu Gly Met Asp Glu Met Glu Phe Thr Glu Ala Glu Ser Asn Met Asn 
                405                 410                 415     


Asp Leu Val Ser Glu Tyr Gln Gln Tyr Gln Asp Ala Thr Ala Glu Glu 
            420                 425                 430         


Glu Glu Asp Phe Gly Glu Glu Ala Glu Glu Glu Ala 
        435                 440                 


<210>  1412
<211>  445
<212>  PRT
<213>  Human

<400>  1412

Met Arg Glu Ile Val His Ile Gln Ala Gly Gln Cys Gly Asn Gln Ile 
1               5                   10                  15      


Gly Ala Lys Phe Trp Glu Val Ile Ser Asp Glu His Gly Ile Asp Pro 
            20                  25                  30          


Thr Gly Ser Tyr His Gly Asp Ser Asp Leu Gln Leu Glu Arg Ile Asn 
        35                  40                  45              


Val Tyr Tyr Asn Glu Ala Ala Gly Asn Lys Tyr Val Pro Arg Ala Ile 
    50                  55                  60                  


Leu Val Asp Leu Glu Pro Gly Thr Met Asp Ser Val Arg Ser Gly Pro 
65                  70                  75                  80  


Phe Gly Gln Ile Phe Arg Pro Asp Asn Phe Val Phe Gly Gln Ser Gly 
                85                  90                  95      


Ala Gly Asn Asn Trp Ala Lys Gly His Tyr Thr Glu Gly Ala Glu Leu 
            100                 105                 110         


Val Asp Ser Val Leu Asp Val Val Arg Lys Glu Ser Glu Ser Cys Asp 
        115                 120                 125             


Cys Leu Gln Gly Phe Gln Leu Thr His Ser Leu Gly Gly Gly Thr Gly 
    130                 135                 140                 


Ser Gly Met Gly Thr Leu Leu Ile Ser Lys Ile Arg Glu Glu Tyr Pro 
145                 150                 155                 160 


Asp Arg Ile Met Asn Thr Phe Ser Val Met Pro Ser Pro Lys Val Ser 
                165                 170                 175     


Asp Thr Val Val Glu Pro Tyr Asn Ala Thr Leu Ser Val His Gln Leu 
            180                 185                 190         


Val Glu Asn Thr Asp Glu Thr Tyr Ser Ile Asp Asn Glu Ala Leu Tyr 
        195                 200                 205             


Asp Ile Cys Phe Arg Thr Leu Lys Leu Thr Thr Pro Thr Tyr Gly Asp 
    210                 215                 220                 


Leu Asn His Leu Val Ser Ala Thr Met Ser Gly Val Thr Thr Cys Leu 
225                 230                 235                 240 


Arg Phe Pro Gly Gln Leu Asn Ala Asp Leu Arg Lys Leu Ala Val Asn 
                245                 250                 255     


Met Val Pro Phe Pro Arg Leu His Phe Phe Met Pro Gly Phe Ala Pro 
            260                 265                 270         


Leu Thr Ser Arg Gly Ser Gln Gln Tyr Arg Ala Leu Thr Val Pro Glu 
        275                 280                 285             


Leu Thr Gln Gln Met Phe Asp Ser Lys Asn Met Met Ala Ala Cys Asp 
    290                 295                 300                 


Pro Arg His Gly Arg Tyr Leu Thr Val Ala Ala Ile Phe Arg Gly Arg 
305                 310                 315                 320 


Met Ser Met Lys Glu Val Asp Glu Gln Met Leu Asn Val Gln Asn Lys 
                325                 330                 335     


Asn Ser Ser Tyr Phe Val Glu Trp Ile Pro Asn Asn Val Lys Thr Ala 
            340                 345                 350         


Val Cys Asp Ile Pro Pro Arg Gly Leu Lys Met Ser Ala Thr Phe Ile 
        355                 360                 365             


Gly Asn Ser Thr Ala Ile Gln Glu Leu Phe Lys Arg Ile Ser Glu Gln 
    370                 375                 380                 


Phe Thr Ala Met Phe Arg Arg Lys Ala Phe Leu His Trp Tyr Thr Gly 
385                 390                 395                 400 


Glu Gly Met Asp Glu Met Glu Phe Thr Glu Ala Glu Ser Asn Met Asn 
                405                 410                 415     


Asp Leu Val Ser Glu Tyr Gln Gln Tyr Gln Asp Ala Thr Ala Asp Glu 
            420                 425                 430         


Gln Gly Glu Phe Glu Glu Glu Glu Gly Glu Asp Glu Ala 
        435                 440                 445 


<210>  1413
<211>  666
<212>  PRT
<213>  Human

<400>  1413

Met Ile His Glu Leu Leu Leu Ala Leu Ser Gly Tyr Pro Gly Ser Ile 
1               5                   10                  15      


Phe Thr Trp Asn Lys Arg Ser Gly Leu Gln Val Ser Gln Asp Phe Pro 
            20                  25                  30          


Phe Leu His Pro Ser Glu Thr Ser Val Leu Asn Arg Leu Cys Arg Leu 
        35                  40                  45              


Gly Thr Asp Tyr Ile Arg Phe Thr Glu Phe Ile Glu Gln Tyr Thr Gly 
    50                  55                  60                  


His Val Gln Gln Gln Asp His His Pro Ser Gln Gln Gly Gln Gly Gly 
65                  70                  75                  80  


Leu His Gly Ile Tyr Leu Arg Ala Phe Cys Thr Gly Leu Asp Ser Val 
                85                  90                  95      


Leu Gln Pro Tyr Arg Gln Ala Leu Leu Asp Leu Glu Gln Glu Phe Leu 
            100                 105                 110         


Gly Asp Pro His Leu Ser Ile Ser His Val Asn Tyr Phe Leu Asp Gln 
        115                 120                 125             


Phe Gln Leu Leu Phe Pro Ser Val Met Val Val Val Glu Gln Ile Lys 
    130                 135                 140                 


Ser Gln Lys Ile His Gly Cys Gln Ile Leu Glu Thr Val Tyr Lys His 
145                 150                 155                 160 


Ser Cys Gly Gly Leu Pro Pro Val Arg Ser Ala Leu Glu Lys Ile Leu 
                165                 170                 175     


Ala Val Cys His Gly Val Met Tyr Lys Gln Leu Ser Ala Trp Met Leu 
            180                 185                 190         


His Gly Leu Leu Leu Asp Gln His Glu Glu Phe Phe Ile Lys Gln Gly 
        195                 200                 205             


Pro Ser Ser Gly Asn Val Ser Ala Gln Pro Glu Glu Asp Glu Glu Asp 
    210                 215                 220                 


Leu Gly Ile Gly Gly Leu Thr Gly Lys Gln Leu Arg Glu Leu Gln Asp 
225                 230                 235                 240 


Leu Arg Leu Ile Glu Glu Glu Asn Met Leu Ala Pro Ser Leu Lys Gln 
                245                 250                 255     


Phe Ser Leu Arg Val Glu Ile Leu Pro Ser Tyr Ile Pro Val Arg Val 
            260                 265                 270         


Ala Glu Lys Ile Leu Phe Val Gly Glu Ser Val Gln Met Phe Glu Asn 
        275                 280                 285             


Gln Asn Val Asn Leu Thr Arg Lys Gly Ser Ile Leu Lys Asn Gln Glu 
    290                 295                 300                 


Asp Thr Phe Ala Ala Glu Leu His Arg Leu Lys Gln Gln Pro Leu Phe 
305                 310                 315                 320 


Ser Leu Val Asp Phe Glu Gln Val Val Asp Arg Ile Arg Ser Thr Val 
                325                 330                 335     


Ala Glu His Leu Trp Lys Leu Met Val Glu Glu Ser Asp Leu Leu Gly 
            340                 345                 350         


Gln Leu Lys Ile Ile Lys Asp Phe Tyr Leu Leu Gly Arg Gly Glu Leu 
        355                 360                 365             


Phe Gln Ala Phe Ile Asp Thr Ala Gln His Met Leu Lys Thr Pro Pro 
    370                 375                 380                 


Thr Ala Val Thr Glu His Asp Val Asn Val Ala Phe Gln Gln Ser Ala 
385                 390                 395                 400 


His Lys Val Leu Leu Asp Asp Asp Asn Leu Leu Pro Leu Leu His Leu 
                405                 410                 415     


Thr Ile Glu Tyr His Gly Lys Glu His Lys Asp Ala Thr Gln Ala Arg 
            420                 425                 430         


Glu Gly Pro Ser Arg Glu Thr Ser Pro Arg Glu Ala Pro Ala Ser Gly 
        435                 440                 445             


Trp Ala Ala Leu Gly Leu Ser Tyr Lys Val Gln Trp Pro Leu His Ile 
    450                 455                 460                 


Leu Phe Thr Pro Ala Val Leu Glu Lys Tyr Asn Val Val Phe Lys Tyr 
465                 470                 475                 480 


Leu Leu Ser Val Arg Arg Val Gln Ala Glu Leu Gln His Cys Trp Ala 
                485                 490                 495     


Leu Gln Met Gln Arg Lys His Leu Lys Ser Asn Gln Thr Asp Ala Ile 
            500                 505                 510         


Lys Trp Arg Leu Arg Asn His Met Ala Phe Leu Val Asp Asn Leu Gln 
        515                 520                 525             


Tyr Tyr Leu Gln Val Asp Val Leu Glu Ser Gln Phe Ser Gln Leu Leu 
    530                 535                 540                 


His Gln Ile Asn Ser Thr Arg Asp Phe Glu Ser Ile Arg Leu Ala His 
545                 550                 555                 560 


Asp His Phe Leu Ser Asn Leu Leu Ala Gln Ser Phe Ile Leu Leu Lys 
                565                 570                 575     


Pro Val Phe His Cys Leu Asn Glu Ile Leu Asp Leu Cys His Ser Phe 
            580                 585                 590         


Cys Ser Leu Val Ser Gln Asn Leu Gly Pro Leu Asp Glu Arg Gly Ala 
        595                 600                 605             


Ala Gln Leu Ser Ile Leu Val Lys Gly Phe Ser Arg Gln Ser Ser Leu 
    610                 615                 620                 


Leu Phe Lys Ile Leu Ser Ser Val Arg Asn His Gln Ile Asn Ser Asp 
625                 630                 635                 640 


Leu Ala Gln Leu Leu Leu Arg Leu Asp Tyr Asn Lys Tyr Tyr Thr Gln 
                645                 650                 655     


Ala Gly Gly Thr Leu Gly Ser Phe Gly Met 
            660                 665     


<210>  1414
<211>  405
<212>  PRT
<213>  Human

<400>  1414

Met Phe Val Gln Glu Glu Lys Ile Phe Ala Gly Lys Val Leu Arg Leu 
1               5                   10                  15      


His Ile Cys Ala Ser Asp Gly Ala Glu Trp Leu Glu Glu Ala Thr Glu 
            20                  25                  30          


Asp Thr Ser Val Glu Lys Leu Lys Glu Arg Cys Leu Lys His Cys Ala 
        35                  40                  45              


His Gly Ser Leu Glu Asp Pro Lys Ser Ile Thr His His Lys Leu Ile 
    50                  55                  60                  


His Ala Ala Ser Glu Arg Val Leu Ser Asp Ala Arg Thr Ile Leu Glu 
65                  70                  75                  80  


Glu Asn Ile Gln Asp Gln Asp Val Leu Leu Leu Ile Lys Lys Arg Ala 
                85                  90                  95      


Pro Ser Pro Leu Pro Lys Met Ala Asp Val Ser Ala Glu Glu Lys Lys 
            100                 105                 110         


Lys Gln Asp Gln Lys Ala Pro Asp Lys Glu Ala Ile Leu Arg Ala Thr 
        115                 120                 125             


Ala Asn Leu Pro Ser Tyr Asn Met Asp Arg Ala Ala Val Gln Thr Asn 
    130                 135                 140                 


Met Arg Asp Phe Gln Thr Glu Leu Arg Lys Ile Leu Val Ser Leu Ile 
145                 150                 155                 160 


Glu Val Ala Gln Lys Leu Leu Ala Leu Asn Pro Asp Ala Val Glu Leu 
                165                 170                 175     


Phe Lys Lys Ala Asn Ala Met Leu Asp Glu Asp Glu Asp Glu Arg Val 
            180                 185                 190         


Asp Glu Ala Ala Leu Arg Gln Leu Thr Glu Met Gly Phe Pro Glu Asn 
        195                 200                 205             


Arg Ala Thr Lys Ala Leu Gln Leu Asn His Met Ser Val Pro Gln Ala 
    210                 215                 220                 


Met Glu Trp Leu Ile Glu His Ala Glu Asp Pro Thr Ile Asp Thr Pro 
225                 230                 235                 240 


Leu Pro Gly Gln Ala Pro Pro Glu Ala Glu Gly Ala Thr Ala Ala Ala 
                245                 250                 255     


Ser Glu Ala Ala Ala Gly Ala Ser Ala Thr Asp Glu Glu Ala Arg Asp 
            260                 265                 270         


Glu Leu Thr Glu Ile Phe Lys Lys Ile Arg Arg Lys Arg Glu Phe Arg 
        275                 280                 285             


Ala Asp Ala Arg Ala Val Ile Ser Leu Met Glu Met Gly Phe Asp Glu 
    290                 295                 300                 


Lys Glu Val Ile Asp Ala Leu Arg Val Asn Asn Asn Gln Gln Asn Ala 
305                 310                 315                 320 


Ala Cys Glu Trp Leu Leu Gly Asp Arg Lys Pro Ser Pro Glu Glu Leu 
                325                 330                 335     


Asp Lys Gly Ile Asp Pro Asp Ser Pro Leu Phe Gln Ala Ile Leu Asp 
            340                 345                 350         


Asn Pro Val Val Gln Leu Gly Leu Thr Asn Pro Lys Thr Leu Leu Ala 
        355                 360                 365             


Phe Glu Asp Met Leu Glu Asn Pro Leu Asn Ser Thr Gln Trp Met Asn 
    370                 375                 380                 


Asp Pro Glu Thr Gly Pro Val Met Leu Gln Ile Ser Arg Ile Phe Gln 
385                 390                 395                 400 


Thr Leu Asn Arg Thr 
                405 


<210>  1415
<211>  685
<212>  PRT
<213>  Human

<400>  1415

Met Gln Ile Phe Val Lys Thr Leu Thr Gly Lys Thr Ile Thr Leu Glu 
1               5                   10                  15      


Val Glu Pro Ser Asp Thr Ile Glu Asn Val Lys Ala Lys Ile Gln Asp 
            20                  25                  30          


Lys Glu Gly Ile Pro Pro Asp Gln Gln Arg Leu Ile Phe Ala Gly Lys 
        35                  40                  45              


Gln Leu Glu Asp Gly Arg Thr Leu Ser Asp Tyr Asn Ile Gln Lys Glu 
    50                  55                  60                  


Ser Thr Leu His Leu Val Leu Arg Leu Arg Gly Gly Met Gln Ile Phe 
65                  70                  75                  80  


Val Lys Thr Leu Thr Gly Lys Thr Ile Thr Leu Glu Val Glu Pro Ser 
                85                  90                  95      


Asp Thr Ile Glu Asn Val Lys Ala Lys Ile Gln Asp Lys Glu Gly Ile 
            100                 105                 110         


Pro Pro Asp Gln Gln Arg Leu Ile Phe Ala Gly Lys Gln Leu Glu Asp 
        115                 120                 125             


Gly Arg Thr Leu Ser Asp Tyr Asn Ile Gln Lys Glu Ser Thr Leu His 
    130                 135                 140                 


Leu Val Leu Arg Leu Arg Gly Gly Met Gln Ile Phe Val Lys Thr Leu 
145                 150                 155                 160 


Thr Gly Lys Thr Ile Thr Leu Glu Val Glu Pro Ser Asp Thr Ile Glu 
                165                 170                 175     


Asn Val Lys Ala Lys Ile Gln Asp Lys Glu Gly Ile Pro Ser Asp Gln 
            180                 185                 190         


Gln Arg Leu Ile Phe Ala Gly Lys Gln Leu Glu Asp Gly Arg Thr Leu 
        195                 200                 205             


Ser Asp Tyr Asn Ile Gln Lys Glu Ser Thr Leu His Leu Val Leu Arg 
    210                 215                 220                 


Leu Arg Gly Gly Met Gln Ile Phe Val Lys Thr Leu Thr Gly Lys Thr 
225                 230                 235                 240 


Ile Thr Leu Glu Val Glu Pro Ser Asp Thr Ile Glu Asn Val Lys Ala 
                245                 250                 255     


Lys Ile Gln Asp Lys Glu Gly Ile Pro Pro Asp Gln Gln Arg Leu Ile 
            260                 265                 270         


Phe Ala Gly Lys Gln Leu Glu Asp Gly Arg Thr Leu Ser Asp Tyr Asn 
        275                 280                 285             


Ile Gln Lys Glu Ser Thr Leu His Leu Val Leu Arg Leu Arg Gly Gly 
    290                 295                 300                 


Met Gln Ile Phe Val Lys Thr Leu Thr Gly Lys Thr Ile Thr Leu Glu 
305                 310                 315                 320 


Val Glu Pro Ser Asp Thr Ile Glu Asn Val Lys Ala Lys Ile Gln Asp 
                325                 330                 335     


Lys Glu Gly Ile Pro Pro Asp Gln Gln Arg Leu Ile Phe Ala Gly Lys 
            340                 345                 350         


Gln Leu Glu Asp Gly Arg Thr Leu Ser Asp Tyr Asn Ile Gln Lys Glu 
        355                 360                 365             


Ser Thr Leu His Leu Val Leu Arg Leu Arg Gly Gly Met Gln Ile Phe 
    370                 375                 380                 


Val Lys Thr Leu Thr Gly Lys Thr Ile Thr Leu Glu Val Glu Pro Ser 
385                 390                 395                 400 


Asp Thr Ile Glu Asn Val Lys Ala Lys Ile Gln Asp Lys Glu Gly Ile 
                405                 410                 415     


Pro Pro Asp Gln Gln Arg Leu Ile Phe Ala Gly Lys Gln Leu Glu Asp 
            420                 425                 430         


Gly Arg Thr Leu Ser Asp Tyr Asn Ile Gln Lys Glu Ser Thr Leu His 
        435                 440                 445             


Leu Val Leu Arg Leu Arg Gly Gly Met Gln Ile Phe Val Lys Thr Leu 
    450                 455                 460                 


Thr Gly Lys Thr Ile Thr Leu Glu Val Glu Pro Ser Asp Thr Ile Glu 
465                 470                 475                 480 


Asn Val Lys Ala Lys Ile Gln Asp Lys Glu Gly Ile Pro Pro Asp Gln 
                485                 490                 495     


Gln Arg Leu Ile Phe Ala Gly Lys Gln Leu Glu Asp Gly Arg Thr Leu 
            500                 505                 510         


Ser Asp Tyr Asn Ile Gln Lys Glu Ser Thr Leu His Leu Val Leu Arg 
        515                 520                 525             


Leu Arg Gly Gly Met Gln Ile Phe Val Lys Thr Leu Thr Gly Lys Thr 
    530                 535                 540                 


Ile Thr Leu Glu Val Glu Pro Ser Asp Thr Ile Glu Asn Val Lys Ala 
545                 550                 555                 560 


Lys Ile Gln Asp Lys Glu Gly Ile Pro Pro Asp Gln Gln Arg Leu Ile 
                565                 570                 575     


Phe Ala Gly Lys Gln Leu Glu Asp Gly Arg Thr Leu Ser Asp Tyr Asn 
            580                 585                 590         


Ile Gln Lys Glu Ser Thr Leu His Leu Val Leu Arg Leu Arg Gly Gly 
        595                 600                 605             


Met Gln Ile Phe Val Lys Thr Leu Thr Gly Lys Thr Ile Thr Leu Glu 
    610                 615                 620                 


Val Glu Pro Ser Asp Thr Ile Glu Asn Val Lys Ala Lys Ile Gln Asp 
625                 630                 635                 640 


Lys Glu Gly Ile Pro Pro Asp Gln Gln Arg Leu Ile Phe Ala Gly Lys 
                645                 650                 655     


Gln Leu Glu Asp Gly Arg Thr Leu Ser Asp Tyr Asn Ile Gln Lys Glu 
            660                 665                 670         


Ser Thr Leu His Leu Val Leu Arg Leu Arg Gly Gly Val 
        675                 680                 685 


<210>  1416
<211>  422
<212>  PRT
<213>  Human

<400>  1416

Met Gln Gln Pro Gln Pro Gln Gly Gln Gln Gln Pro Gly Pro Gly Gln 
1               5                   10                  15      


Gln Leu Gly Gly Gln Gly Ala Ala Pro Gly Ala Gly Gly Gly Pro Gly 
            20                  25                  30          


Gly Gly Pro Gly Pro Gly Pro Cys Leu Arg Arg Glu Leu Lys Leu Leu 
        35                  40                  45              


Glu Ser Ile Phe His Arg Gly His Glu Arg Phe Arg Ile Ala Ser Ala 
    50                  55                  60                  


Cys Leu Asp Glu Leu Ser Cys Glu Phe Leu Leu Ala Gly Ala Gly Gly 
65                  70                  75                  80  


Ala Gly Ala Gly Ala Ala Pro Gly Pro His Leu Pro Pro Arg Gly Ser 
                85                  90                  95      


Val Pro Gly Asp Pro Val Arg Ile His Cys Asn Ile Thr Glu Ser Tyr 
            100                 105                 110         


Pro Ala Val Pro Pro Ile Trp Ser Val Glu Ser Asp Asp Pro Asn Leu 
        115                 120                 125             


Ala Ala Val Leu Glu Arg Leu Val Asp Ile Lys Lys Gly Asn Thr Leu 
    130                 135                 140                 


Leu Leu Gln His Leu Lys Arg Ile Ile Ser Asp Leu Cys Lys Leu Tyr 
145                 150                 155                 160 


Asn Leu Pro Gln His Pro Asp Val Glu Met Leu Asp Gln Pro Leu Pro 
                165                 170                 175     


Ala Glu Gln Cys Thr Gln Glu Asp Val Ser Ser Glu Asp Glu Asp Glu 
            180                 185                 190         


Glu Met Pro Glu Asp Thr Glu Asp Leu Asp His Tyr Glu Met Lys Glu 
        195                 200                 205             


Glu Glu Pro Ala Glu Gly Lys Lys Ser Glu Asp Asp Gly Ile Gly Lys 
    210                 215                 220                 


Glu Asn Leu Ala Ile Leu Glu Lys Ile Lys Lys Asn Gln Arg Gln Asp 
225                 230                 235                 240 


Tyr Leu Asn Gly Ala Val Ser Gly Ser Val Gln Ala Thr Asp Arg Leu 
                245                 250                 255     


Met Lys Glu Leu Arg Asp Ile Tyr Arg Ser Gln Ser Phe Lys Gly Gly 
            260                 265                 270         


Asn Tyr Ala Val Glu Leu Val Asn Asp Ser Leu Tyr Asp Trp Asn Val 
        275                 280                 285             


Lys Leu Leu Lys Val Asp Gln Asp Ser Ala Leu His Asn Asp Leu Gln 
    290                 295                 300                 


Ile Leu Lys Glu Lys Glu Gly Ala Asp Phe Ile Leu Leu Asn Phe Ser 
305                 310                 315                 320 


Phe Lys Asp Asn Phe Pro Phe Asp Pro Pro Phe Val Arg Val Val Ser 
                325                 330                 335     


Pro Val Leu Ser Gly Gly Tyr Val Leu Gly Gly Gly Ala Ile Cys Met 
            340                 345                 350         


Glu Leu Leu Thr Lys Gln Gly Trp Ser Ser Ala Tyr Ser Ile Glu Ser 
        355                 360                 365             


Val Ile Met Gln Ile Ser Ala Thr Leu Val Lys Gly Lys Ala Arg Val 
    370                 375                 380                 


Gln Phe Gly Ala Asn Lys Ser Gln Tyr Ser Leu Thr Arg Ala Gln Gln 
385                 390                 395                 400 


Ser Tyr Lys Ser Leu Val Gln Ile His Glu Lys Asn Gly Trp Tyr Thr 
                405                 410                 415     


Pro Pro Lys Glu Asp Gly 
            420         


<210>  1417
<211>  470
<212>  PRT
<213>  Human

<400>  1417

Met Lys Glu Glu Lys Glu His Arg Pro Lys Glu Lys Arg Val Thr Leu 
1               5                   10                  15      


Leu Thr Pro Ala Gly Ala Thr Gly Ser Gly Gly Gly Thr Ser Gly Asp 
            20                  25                  30          


Ser Ser Lys Gly Glu Asp Lys Gln Asp Arg Asn Lys Glu Lys Lys Glu 
        35                  40                  45              


Ala Leu Ser Lys Val Val Ile Arg Arg Leu Pro Pro Thr Leu Thr Lys 
    50                  55                  60                  


Glu Gln Leu Gln Glu His Leu Gln Pro Met Pro Glu His Asp Tyr Phe 
65                  70                  75                  80  


Glu Phe Phe Ser Asn Asp Thr Ser Leu Tyr Pro His Met Tyr Ala Arg 
                85                  90                  95      


Ala Tyr Ile Asn Phe Lys Asn Gln Glu Asp Ile Ile Leu Phe Arg Asp 
            100                 105                 110         


Arg Phe Asp Gly Tyr Val Phe Leu Asp Asn Lys Gly Gln Glu Tyr Pro 
        115                 120                 125             


Ala Ile Val Glu Phe Ala Pro Phe Gln Lys Ala Ala Lys Lys Lys Thr 
    130                 135                 140                 


Lys Lys Arg Asp Thr Lys Val Gly Thr Ile Asp Asp Asp Pro Glu Tyr 
145                 150                 155                 160 


Arg Lys Phe Leu Glu Ser Tyr Ala Thr Asp Asn Glu Lys Met Thr Ser 
                165                 170                 175     


Thr Pro Glu Thr Leu Leu Glu Glu Ile Glu Ala Lys Asn Arg Glu Leu 
            180                 185                 190         


Ile Ala Lys Lys Thr Thr Pro Leu Leu Ser Phe Leu Lys Asn Lys Gln 
        195                 200                 205             


Arg Met Arg Glu Glu Lys Arg Glu Glu Arg Arg Arg Arg Glu Ile Glu 
    210                 215                 220                 


Arg Lys Arg Gln Arg Glu Glu Glu Arg Arg Lys Trp Lys Glu Glu Glu 
225                 230                 235                 240 


Lys Arg Lys Arg Lys Asp Ile Glu Lys Leu Lys Lys Ile Asp Arg Ile 
                245                 250                 255     


Pro Glu Arg Asp Lys Leu Lys Asp Glu Pro Lys Ile Lys Leu Leu Lys 
            260                 265                 270         


Lys Pro Glu Lys Gly Asp Glu Lys Glu Leu Asp Lys Arg Glu Lys Ala 
        275                 280                 285             


Lys Lys Leu Asp Lys Glu Asn Leu Ser Asp Glu Arg Ala Ser Gly Gln 
    290                 295                 300                 


Ser Cys Thr Leu Pro Lys Arg Ser Asp Ser Glu Leu Lys Asp Glu Lys 
305                 310                 315                 320 


Pro Lys Arg Pro Glu Asp Glu Ser Gly Arg Asp Tyr Arg Glu Arg Glu 
                325                 330                 335     


Arg Glu Tyr Glu Arg Asp Gln Glu Arg Ile Leu Arg Glu Arg Glu Arg 
            340                 345                 350         


Leu Lys Arg Gln Glu Glu Glu Arg Arg Arg Gln Lys Glu Arg Tyr Glu 
        355                 360                 365             


Lys Glu Lys Thr Phe Lys Arg Lys Glu Glu Glu Met Lys Lys Glu Lys 
    370                 375                 380                 


Asp Thr Leu Arg Asp Lys Gly Lys Lys Ala Glu Ser Thr Glu Ser Ile 
385                 390                 395                 400 


Gly Ser Ser Glu Lys Thr Glu Lys Lys Glu Glu Val Val Lys Arg Asp 
                405                 410                 415     


Arg Ile Arg Asn Lys Asp Arg Pro Ala Met Gln Leu Tyr Gln Pro Gly 
            420                 425                 430         


Ala Arg Ser Arg Asn Arg Leu Cys Pro Pro Asp Asp Ser Thr Lys Ser 
        435                 440                 445             


Gly Asp Ser Ala Ala Glu Arg Lys Gln Glu Ser Gly Ile Ser His Arg 
    450                 455                 460                 


Lys Glu Gly Gly Glu Glu 
465                 470 


<210>  1418
<211>  310
<212>  PRT
<213>  Human

<400>  1418

Met Ala Ala Thr Gly Ala Asn Ala Glu Lys Ala Glu Ser His Asn Asp 
1               5                   10                  15      


Cys Pro Val Arg Leu Leu Asn Pro Asn Ile Ala Lys Met Lys Glu Asp 
            20                  25                  30          


Ile Leu Tyr His Phe Asn Leu Thr Thr Ser Arg His Asn Phe Pro Ala 
        35                  40                  45              


Leu Phe Gly Asp Val Lys Phe Val Cys Val Gly Gly Ser Pro Ser Arg 
    50                  55                  60                  


Met Lys Ala Phe Ile Arg Cys Val Gly Ala Glu Leu Gly Leu Asp Cys 
65                  70                  75                  80  


Pro Gly Arg Asp Tyr Pro Asn Ile Cys Ala Gly Thr Asp Arg Tyr Ala 
                85                  90                  95      


Met Tyr Lys Val Gly Pro Val Leu Ser Val Ser His Gly Met Gly Ile 
            100                 105                 110         


Pro Ser Ile Ser Ile Met Leu His Glu Leu Ile Lys Leu Leu Tyr Tyr 
        115                 120                 125             


Ala Arg Cys Ser Asn Val Thr Ile Ile Arg Ile Gly Thr Ser Gly Gly 
    130                 135                 140                 


Ile Gly Leu Glu Pro Gly Thr Val Val Ile Thr Glu Gln Ala Val Asp 
145                 150                 155                 160 


Thr Cys Phe Lys Ala Glu Phe Glu Gln Ile Val Leu Gly Lys Arg Val 
                165                 170                 175     


Ile Arg Lys Thr Asp Leu Asn Lys Lys Leu Val Gln Glu Leu Leu Leu 
            180                 185                 190         


Cys Ser Ala Glu Leu Ser Glu Phe Thr Thr Val Val Gly Asn Thr Met 
        195                 200                 205             


Cys Thr Leu Asp Phe Tyr Glu Gly Gln Gly Arg Leu Asp Gly Ala Leu 
    210                 215                 220                 


Cys Ser Tyr Thr Glu Lys Asp Lys Gln Ala Tyr Leu Glu Ala Ala Tyr 
225                 230                 235                 240 


Ala Ala Gly Val Arg Asn Ile Glu Met Glu Ser Ser Val Phe Ala Ala 
                245                 250                 255     


Met Cys Ser Ala Cys Gly Leu Gln Ala Ala Val Val Cys Val Thr Leu 
            260                 265                 270         


Leu Asn Arg Leu Glu Gly Asp Gln Ile Ser Ser Pro Arg Asn Val Leu 
        275                 280                 285             


Ser Glu Tyr Gln Gln Arg Pro Gln Arg Leu Val Ser Tyr Phe Ile Lys 
    290                 295                 300                 


Lys Lys Leu Ser Lys Ala 
305                 310 


<210>  1419
<211>  445
<212>  PRT
<213>  Human

<400>  1419

Met Leu Pro Trp Thr Ala Leu Gly Leu Ala Leu Ser Leu Arg Leu Ala 
1               5                   10                  15      


Leu Ala Arg Ser Gly Ala Glu Arg Gly Pro Pro Ala Ser Ala Pro Arg 
            20                  25                  30          


Gly Asp Leu Met Phe Leu Leu Asp Ser Ser Ala Ser Val Ser His Tyr 
        35                  40                  45              


Glu Phe Ser Arg Val Arg Glu Phe Val Gly Gln Leu Val Ala Pro Leu 
    50                  55                  60                  


Pro Leu Gly Thr Gly Ala Leu Arg Ala Ser Leu Val His Val Gly Ser 
65                  70                  75                  80  


Arg Pro Tyr Thr Glu Phe Pro Phe Gly Gln His Ser Ser Gly Glu Ala 
                85                  90                  95      


Ala Gln Asp Ala Val Arg Ala Ser Ala Gln Arg Met Gly Asp Thr His 
            100                 105                 110         


Thr Gly Leu Ala Leu Val Tyr Ala Lys Glu Gln Leu Phe Ala Glu Ala 
        115                 120                 125             


Ser Gly Ala Arg Pro Gly Val Pro Lys Val Leu Val Trp Val Thr Asp 
    130                 135                 140                 


Gly Gly Ser Ser Asp Pro Val Gly Pro Pro Met Gln Glu Leu Lys Asp 
145                 150                 155                 160 


Leu Gly Val Thr Val Phe Ile Val Ser Thr Gly Arg Gly Asn Phe Leu 
                165                 170                 175     


Glu Leu Ser Ala Ala Ala Ser Ala Pro Ala Glu Lys His Leu His Phe 
            180                 185                 190         


Val Asp Val Asp Asp Leu His Ile Ile Val Gln Glu Leu Arg Gly Ser 
        195                 200                 205             


Ile Leu Asp Ala Met Arg Pro Gln Gln Leu His Ala Thr Glu Ile Thr 
    210                 215                 220                 


Ser Ser Gly Phe Arg Leu Ala Trp Pro Pro Leu Leu Thr Ala Asp Ser 
225                 230                 235                 240 


Gly Tyr Tyr Val Leu Glu Leu Val Pro Ser Ala Gln Pro Gly Ala Ala 
                245                 250                 255     


Arg Arg Gln Gln Leu Pro Gly Asn Ala Thr Asp Trp Ile Trp Ala Gly 
            260                 265                 270         


Leu Asp Pro Asp Thr Asp Tyr Asp Val Ala Leu Val Pro Glu Ser Asn 
        275                 280                 285             


Val Arg Leu Leu Arg Pro Gln Ile Leu Arg Val Arg Thr Arg Pro Gly 
    290                 295                 300                 


Glu Ala Gly Pro Gly Ala Ser Gly Pro Glu Ser Gly Ala Gly Pro Ala 
305                 310                 315                 320 


Pro Thr Gln Leu Ala Ala Leu Pro Ala Pro Glu Glu Ala Gly Pro Glu 
                325                 330                 335     


Arg Ile Val Ile Ser His Ala Arg Pro Arg Ser Leu Arg Val Ser Trp 
            340                 345                 350         


Ala Pro Ala Leu Gly Ser Ala Ala Ala Leu Gly Tyr His Val Gln Phe 
        355                 360                 365             


Gly Pro Leu Arg Gly Gly Glu Ala Gln Arg Val Glu Val Pro Ala Gly 
    370                 375                 380                 


Arg Asn Cys Thr Thr Leu Gln Gly Leu Ala Pro Gly Thr Ala Tyr Leu 
385                 390                 395                 400 


Val Thr Val Thr Ala Ala Phe Arg Ser Gly Arg Glu Ser Ala Leu Ser 
                405                 410                 415     


Ala Lys Ala Cys Thr Pro Asp Gly Pro Arg Pro Arg Pro Arg Pro Val 
            420                 425                 430         


Pro Arg Ala Pro Thr Pro Gly Thr Ala Ser Arg Glu Pro 
        435                 440                 445 


<210>  1420
<211>  404
<212>  PRT
<213>  Human

<400>  1420

Met Glu Ala Gly Glu Glu Pro Leu Leu Leu Ala Glu Leu Lys Pro Gly 
1               5                   10                  15      


Arg Pro His Gln Phe Asp Trp Lys Ser Ser Cys Glu Thr Trp Ser Val 
            20                  25                  30          


Ala Phe Ser Pro Asp Gly Ser Trp Phe Ala Trp Ser Gln Gly His Cys 
        35                  40                  45              


Ile Val Lys Leu Ile Pro Trp Pro Leu Glu Glu Gln Phe Ile Pro Lys 
    50                  55                  60                  


Gly Phe Glu Ala Lys Ser Arg Ser Ser Lys Asn Glu Thr Lys Gly Arg 
65                  70                  75                  80  


Gly Ser Pro Lys Glu Lys Thr Leu Asp Cys Gly Gln Ile Val Trp Gly 
                85                  90                  95      


Leu Ala Phe Ser Pro Trp Pro Ser Pro Pro Ser Arg Lys Leu Trp Ala 
            100                 105                 110         


Arg His His Pro Gln Val Pro Asp Val Ser Cys Leu Val Leu Ala Thr 
        115                 120                 125             


Gly Leu Asn Asp Gly Gln Ile Lys Ile Trp Glu Val Gln Thr Gly Leu 
    130                 135                 140                 


Leu Leu Leu Asn Leu Ser Gly His Gln Asp Val Val Arg Asp Leu Ser 
145                 150                 155                 160 


Phe Thr Pro Ser Gly Ser Leu Ile Leu Val Ser Ala Ser Arg Asp Lys 
                165                 170                 175     


Thr Leu Arg Ile Trp Asp Leu Asn Lys His Gly Lys Gln Ile Gln Val 
            180                 185                 190         


Leu Ser Gly His Leu Gln Trp Val Tyr Cys Cys Ser Ile Ser Pro Asp 
        195                 200                 205             


Cys Ser Met Leu Cys Ser Ala Ala Gly Glu Lys Ser Val Phe Leu Trp 
    210                 215                 220                 


Ser Met Arg Ser Tyr Thr Leu Ile Arg Lys Leu Glu Gly His Gln Ser 
225                 230                 235                 240 


Ser Val Val Ser Cys Asp Phe Ser Pro Asp Ser Ala Leu Leu Val Thr 
                245                 250                 255     


Ala Ser Tyr Asp Thr Asn Val Ile Met Trp Asp Pro Tyr Thr Gly Glu 
            260                 265                 270         


Arg Leu Arg Ser Leu His His Thr Gln Val Asp Pro Ala Met Asp Asp 
        275                 280                 285             


Ser Asp Val His Ile Ser Ser Leu Arg Ser Val Cys Phe Ser Pro Glu 
    290                 295                 300                 


Gly Leu Tyr Leu Ala Thr Val Ala Asp Asp Arg Leu Leu Arg Ile Trp 
305                 310                 315                 320 


Ala Leu Glu Leu Lys Thr Pro Ile Ala Phe Ala Pro Met Thr Asn Gly 
                325                 330                 335     


Leu Cys Cys Thr Phe Phe Pro His Gly Gly Val Ile Ala Thr Gly Thr 
            340                 345                 350         


Arg Asp Gly His Val Gln Phe Trp Thr Ala Pro Arg Val Leu Ser Ser 
        355                 360                 365             


Leu Lys His Leu Cys Arg Lys Ala Leu Arg Ser Phe Leu Thr Thr Tyr 
    370                 375                 380                 


Gln Val Leu Ala Leu Pro Ile Pro Lys Lys Met Lys Glu Phe Leu Thr 
385                 390                 395                 400 


Tyr Arg Thr Phe 
                


<210>  1421
<211>  810
<212>  PRT
<213>  Human

<400>  1421

Met Pro Asn Gln Gly Glu Asp Cys Tyr Phe Phe Phe Tyr Ser Thr Cys 
1               5                   10                  15      


Thr Lys Gly Asp Ser Cys Pro Phe Arg His Cys Glu Ala Ala Ile Gly 
            20                  25                  30          


Asn Glu Thr Val Cys Thr Leu Trp Gln Glu Gly Arg Cys Phe Arg Gln 
        35                  40                  45              


Val Cys Arg Phe Arg His Met Glu Ile Asp Lys Lys Arg Ser Glu Ile 
    50                  55                  60                  


Pro Cys Tyr Trp Glu Asn Gln Pro Thr Gly Cys Gln Lys Leu Asn Cys 
65                  70                  75                  80  


Ala Phe His His Asn Arg Gly Arg Tyr Val Asp Gly Leu Phe Leu Pro 
                85                  90                  95      


Pro Ser Lys Thr Val Leu Pro Thr Val Pro Glu Ser Pro Glu Glu Glu 
            100                 105                 110         


Val Lys Ala Ser Gln Leu Ser Val Gln Gln Asn Lys Leu Ser Val Gln 
        115                 120                 125             


Ser Asn Pro Ser Pro Gln Leu Arg Ser Val Met Lys Val Glu Ser Ser 
    130                 135                 140                 


Glu Asn Val Pro Ser Pro Thr His Pro Pro Val Val Ile Asn Ala Ala 
145                 150                 155                 160 


Asp Asp Asp Glu Asp Asp Asp Asp Gln Phe Ser Glu Glu Gly Asp Glu 
                165                 170                 175     


Thr Lys Thr Pro Thr Leu Gln Pro Thr Pro Glu Val His Asn Gly Leu 
            180                 185                 190         


Arg Val Thr Ser Val Arg Lys Pro Ala Val Asn Ile Lys Gln Gly Glu 
        195                 200                 205             


Cys Leu Asn Phe Gly Ile Lys Thr Leu Glu Glu Ile Lys Ser Lys Lys 
    210                 215                 220                 


Met Lys Glu Lys Ser Lys Lys Gln Gly Glu Gly Ser Ser Gly Val Ser 
225                 230                 235                 240 


Ser Leu Leu Leu His Pro Glu Pro Val Pro Gly Pro Glu Lys Glu Asn 
                245                 250                 255     


Val Arg Thr Val Val Arg Thr Val Thr Leu Ser Thr Lys Gln Gly Glu 
            260                 265                 270         


Glu Pro Leu Val Arg Leu Ser Leu Thr Glu Arg Leu Gly Lys Arg Lys 
        275                 280                 285             


Phe Ser Ala Gly Gly Asp Ser Asp Pro Pro Leu Lys Arg Ser Leu Ala 
    290                 295                 300                 


Gln Arg Leu Gly Lys Lys Val Glu Ala Pro Glu Thr Asn Ile Asp Lys 
305                 310                 315                 320 


Thr Pro Lys Lys Ala Gln Val Ser Lys Ser Leu Lys Glu Arg Leu Gly 
                325                 330                 335     


Met Ser Ala Asp Pro Asp Asn Glu Asp Ala Thr Asp Lys Val Asn Lys 
            340                 345                 350         


Val Gly Glu Ile His Val Lys Thr Leu Glu Glu Ile Leu Leu Glu Arg 
        355                 360                 365             


Ala Ser Gln Lys Arg Gly Glu Leu Gln Thr Lys Leu Lys Thr Glu Gly 
    370                 375                 380                 


Pro Ser Lys Thr Asp Asp Ser Thr Ser Gly Ala Arg Ser Ser Ser Thr 
385                 390                 395                 400 


Ile Arg Ile Lys Thr Phe Ser Glu Val Leu Ala Glu Lys Lys His Arg 
                405                 410                 415     


Gln Gln Glu Ala Glu Arg Gln Lys Ser Lys Lys Asp Thr Thr Cys Ile 
            420                 425                 430         


Lys Leu Lys Ile Asp Ser Glu Ile Lys Lys Thr Val Val Leu Pro Pro 
        435                 440                 445             


Ile Val Ala Ser Arg Gly Gln Ser Glu Glu Pro Ala Gly Lys Thr Lys 
    450                 455                 460                 


Ser Met Gln Glu Val His Ile Lys Thr Leu Glu Glu Ile Lys Leu Glu 
465                 470                 475                 480 


Lys Ala Leu Arg Val Gln Gln Ser Ser Glu Ser Ser Thr Ser Ser Pro 
                485                 490                 495     


Ser Gln His Glu Ala Thr Pro Gly Ala Arg Arg Leu Leu Arg Ile Thr 
            500                 505                 510         


Lys Arg Thr Gly Met Lys Glu Glu Lys Asn Leu Gln Glu Gly Asn Glu 
        515                 520                 525             


Val Asp Ser Gln Ser Ser Ile Arg Thr Glu Ala Lys Glu Ala Ser Gly 
    530                 535                 540                 


Glu Thr Thr Gly Val Asp Ile Thr Lys Ile Gln Val Lys Arg Cys Glu 
545                 550                 555                 560 


Thr Met Arg Glu Lys His Met Gln Lys Gln Gln Glu Arg Glu Lys Ser 
                565                 570                 575     


Val Leu Thr Pro Leu Arg Gly Asp Val Ala Ser Cys Asn Thr Gln Val 
            580                 585                 590         


Ala Glu Lys Pro Val Leu Thr Ala Val Pro Gly Ile Thr Arg His Leu 
        595                 600                 605             


Thr Lys Arg Leu Pro Thr Lys Ser Ser Gln Lys Val Glu Val Glu Thr 
    610                 615                 620                 


Ser Gly Ile Gly Asp Ser Leu Leu Asn Val Lys Cys Ala Ala Gln Thr 
625                 630                 635                 640 


Leu Glu Lys Arg Gly Lys Ala Lys Pro Lys Val Asn Val Lys Pro Ser 
                645                 650                 655     


Val Val Lys Val Val Ser Ser Pro Lys Leu Ala Pro Lys Arg Lys Ala 
            660                 665                 670         


Val Glu Met His Ala Ala Val Ile Ala Ala Val Lys Pro Leu Ser Ser 
        675                 680                 685             


Ser Ser Val Leu Gln Glu Pro Pro Ala Lys Lys Ala Ala Val Ala Val 
    690                 695                 700                 


Val Pro Leu Val Ser Glu Asp Lys Ser Val Thr Val Pro Glu Ala Glu 
705                 710                 715                 720 


Asn Pro Arg Asp Ser Leu Val Leu Pro Pro Thr Gln Ser Ser Ser Asp 
                725                 730                 735     


Ser Ser Pro Pro Glu Val Ser Gly Pro Ser Ser Ser Gln Met Ser Met 
            740                 745                 750         


Lys Thr Arg Arg Leu Ser Ser Ala Ser Thr Gly Lys Pro Pro Leu Ser 
        755                 760                 765             


Val Glu Asp Asp Phe Glu Lys Leu Ile Trp Glu Ile Ser Gly Gly Lys 
    770                 775                 780                 


Leu Glu Ala Glu Ile Asp Leu Asp Pro Gly Lys Asp Glu Asp Asp Leu 
785                 790                 795                 800 


Leu Leu Glu Leu Ser Glu Met Ile Asp Ser 
                805                 810 


<210>  1422
<211>  426
<212>  PRT
<213>  Human

<400>  1422

Met Pro Pro Lys Lys Gln Ala Gln Ala Gly Gly Ser Lys Lys Ala Glu 
1               5                   10                  15      


Gln Lys Lys Lys Glu Lys Ile Ile Glu Asp Lys Thr Phe Gly Leu Lys 
            20                  25                  30          


Asn Lys Lys Gly Ala Lys Gln Gln Lys Phe Ile Lys Ala Val Thr His 
        35                  40                  45              


Gln Val Lys Phe Gly Gln Gln Asn Pro Arg Gln Val Ala Gln Ser Glu 
    50                  55                  60                  


Ala Glu Lys Lys Leu Lys Lys Asp Asp Lys Lys Lys Glu Leu Gln Glu 
65                  70                  75                  80  


Leu Asn Glu Leu Phe Lys Pro Val Val Ala Ala Gln Lys Ile Ser Lys 
                85                  90                  95      


Gly Ala Asp Pro Lys Ser Val Val Cys Ala Phe Phe Lys Gln Gly Gln 
            100                 105                 110         


Cys Thr Lys Gly Asp Lys Cys Lys Phe Ser His Asp Leu Thr Leu Glu 
        115                 120                 125             


Arg Lys Cys Glu Lys Arg Ser Val Tyr Ile Asp Ala Arg Asp Glu Glu 
    130                 135                 140                 


Leu Glu Lys Asp Thr Met Asp Asn Trp Asp Glu Lys Lys Leu Glu Glu 
145                 150                 155                 160 


Val Val Asn Lys Lys His Gly Glu Ala Glu Lys Lys Lys Pro Lys Thr 
                165                 170                 175     


Gln Ile Val Cys Lys His Phe Leu Glu Ala Ile Glu Asn Asn Lys Tyr 
            180                 185                 190         


Gly Trp Phe Trp Val Cys Pro Gly Gly Gly Asp Ile Cys Met Tyr Arg 
        195                 200                 205             


His Ala Leu Pro Pro Gly Phe Val Leu Lys Lys Asp Lys Lys Lys Glu 
    210                 215                 220                 


Glu Lys Glu Asp Glu Ile Ser Leu Glu Asp Leu Ile Glu Arg Glu Arg 
225                 230                 235                 240 


Ser Ala Leu Gly Pro Asn Val Thr Lys Ile Thr Leu Glu Ser Phe Leu 
                245                 250                 255     


Ala Trp Lys Lys Arg Lys Arg Gln Glu Lys Ile Asp Lys Leu Glu Gln 
            260                 265                 270         


Asp Met Glu Arg Arg Lys Ala Asp Phe Lys Ala Gly Lys Ala Leu Val 
        275                 280                 285             


Ile Ser Gly Arg Glu Val Phe Glu Phe Arg Pro Glu Leu Val Asn Asp 
    290                 295                 300                 


Asp Asp Glu Glu Ala Asp Asp Thr Arg Tyr Thr Gln Gly Thr Gly Gly 
305                 310                 315                 320 


Asp Glu Val Asp Asp Ser Val Ser Val Asn Asp Ile Asp Leu Ser Leu 
                325                 330                 335     


Tyr Ile Pro Arg Asp Val Asp Glu Thr Gly Ile Thr Val Ala Ser Leu 
            340                 345                 350         


Glu Arg Phe Ser Thr Tyr Thr Ser Asp Lys Asp Glu Asn Lys Leu Ser 
        355                 360                 365             


Glu Ala Ser Gly Gly Arg Ala Glu Asn Gly Glu Arg Ser Asp Leu Glu 
    370                 375                 380                 


Glu Asp Asn Glu Arg Glu Gly Thr Glu Asn Gly Ala Ile Asp Ala Val 
385                 390                 395                 400 


Pro Val Asp Glu Asn Leu Phe Thr Gly Glu Asp Leu Asp Glu Leu Glu 
                405                 410                 415     


Glu Glu Leu Asn Thr Leu Asp Leu Glu Glu 
            420                 425     


<210>  1423
<211>  779
<212>  PRT
<213>  Human

<400>  1423

Met Ala Ala Asn Gly Asp Ser Pro Pro Trp Ser Pro Ala Leu Ala Ala 
1               5                   10                  15      


Glu Gly Arg Gly Ser Ser Cys Glu Ala Ser Val Ser Phe Glu Asp Val 
            20                  25                  30          


Thr Val Asp Phe Ser Lys Glu Glu Trp Gln His Leu Asp Pro Ala Gln 
        35                  40                  45              


Arg Arg Leu Tyr Trp Asp Val Thr Leu Glu Asn Tyr Ser His Leu Leu 
    50                  55                  60                  


Ser Val Gly Tyr Gln Ile Pro Lys Ser Glu Ala Ala Phe Lys Leu Glu 
65                  70                  75                  80  


Gln Gly Glu Gly Pro Trp Met Leu Glu Gly Glu Ala Pro His Gln Ser 
                85                  90                  95      


Cys Ser Gly Glu Ala Ile Gly Lys Met Gln Gln Gln Gly Ile Pro Gly 
            100                 105                 110         


Gly Ile Phe Phe His Cys Glu Arg Phe Asp Gln Pro Ile Gly Glu Asp 
        115                 120                 125             


Ser Leu Cys Ser Ile Leu Glu Glu Leu Trp Gln Asp Asn Asp Gln Leu 
    130                 135                 140                 


Glu Gln Arg Gln Glu Asn Gln Asn Asn Leu Leu Ser His Val Lys Val 
145                 150                 155                 160 


Leu Ile Lys Glu Arg Gly Tyr Glu His Lys Asn Ile Glu Lys Ile Ile 
                165                 170                 175     


His Val Thr Thr Lys Leu Val Pro Ser Ile Lys Arg Leu His Asn Cys 
            180                 185                 190         


Asp Thr Ile Leu Lys His Thr Leu Asn Ser His Asn His Asn Arg Asn 
        195                 200                 205             


Ser Ala Thr Lys Asn Leu Gly Lys Ile Phe Gly Asn Gly Asn Asn Phe 
    210                 215                 220                 


Pro His Ser Pro Ser Ser Thr Lys Asn Glu Asn Ala Lys Thr Gly Ala 
225                 230                 235                 240 


Asn Ser Cys Glu His Asp His Tyr Glu Lys His Leu Ser His Lys Gln 
                245                 250                 255     


Ala Pro Thr His His Gln Lys Ile His Pro Glu Glu Lys Leu Tyr Val 
            260                 265                 270         


Cys Thr Glu Cys Val Met Gly Phe Thr Gln Lys Ser His Leu Phe Glu 
        275                 280                 285             


His Gln Arg Ile His Ala Gly Glu Lys Ser Arg Glu Cys Asp Lys Ser 
    290                 295                 300                 


Asn Lys Val Phe Pro Gln Lys Pro Gln Val Asp Val His Pro Ser Val 
305                 310                 315                 320 


Tyr Thr Gly Glu Lys Pro Tyr Leu Cys Thr Gln Cys Gly Lys Val Phe 
                325                 330                 335     


Thr Leu Lys Ser Asn Leu Ile Thr His Gln Lys Ile His Thr Gly Gln 
            340                 345                 350         


Lys Pro Tyr Lys Cys Ser Glu Cys Gly Lys Ala Phe Phe Gln Arg Ser 
        355                 360                 365             


Asp Leu Phe Arg His Leu Arg Ile His Thr Gly Glu Lys Pro Tyr Glu 
    370                 375                 380                 


Cys Ser Glu Cys Gly Lys Gly Phe Ser Gln Asn Ser Asp Leu Ser Ile 
385                 390                 395                 400 


His Gln Lys Thr His Thr Gly Glu Lys His Tyr Glu Cys Asn Glu Cys 
                405                 410                 415     


Gly Lys Ala Phe Thr Arg Lys Ser Ala Leu Arg Met His Gln Arg Ile 
            420                 425                 430         


His Thr Gly Glu Lys Pro Tyr Val Cys Ala Asp Cys Gly Lys Ala Phe 
        435                 440                 445             


Ile Gln Lys Ser His Phe Asn Thr His Gln Arg Ile His Thr Gly Glu 
    450                 455                 460                 


Lys Pro Tyr Glu Cys Ser Asp Cys Gly Lys Ser Phe Thr Lys Lys Ser 
465                 470                 475                 480 


Gln Leu His Val His Gln Arg Ile His Thr Gly Glu Lys Pro Tyr Ile 
                485                 490                 495     


Cys Thr Glu Cys Gly Lys Val Phe Thr His Arg Thr Asn Leu Thr Thr 
            500                 505                 510         


His Gln Lys Thr His Thr Gly Glu Lys Pro Tyr Met Cys Ala Glu Cys 
        515                 520                 525             


Gly Lys Ala Phe Thr Asp Gln Ser Asn Leu Ile Lys His Gln Lys Thr 
    530                 535                 540                 


His Thr Gly Glu Lys Pro Tyr Lys Cys Asn Gly Cys Gly Lys Ala Phe 
545                 550                 555                 560 


Ile Trp Lys Ser Arg Leu Lys Ile His Gln Lys Ser His Ile Gly Glu 
                565                 570                 575     


Arg His Tyr Glu Cys Lys Asp Cys Gly Lys Ala Phe Ile Gln Lys Ser 
            580                 585                 590         


Thr Leu Ser Val His Gln Arg Ile His Thr Gly Glu Lys Pro Tyr Val 
        595                 600                 605             


Cys Pro Glu Cys Gly Lys Ala Phe Ile Gln Lys Ser His Phe Ile Ala 
    610                 615                 620                 


His His Arg Ile His Thr Gly Glu Lys Pro Tyr Glu Cys Ser Asp Cys 
625                 630                 635                 640 


Gly Lys Cys Phe Thr Lys Lys Ser Gln Leu Arg Val His Gln Lys Ile 
                645                 650                 655     


His Thr Gly Glu Lys Pro Asn Ile Cys Ala Glu Cys Gly Lys Ala Phe 
            660                 665                 670         


Thr Asp Arg Ser Asn Leu Ile Thr His Gln Lys Ile His Thr Arg Glu 
        675                 680                 685             


Lys Pro Tyr Glu Cys Gly Asp Cys Gly Lys Thr Phe Thr Trp Lys Ser 
    690                 695                 700                 


Arg Leu Asn Ile His Gln Lys Ser His Thr Gly Glu Arg His Tyr Glu 
705                 710                 715                 720 


Cys Ser Lys Cys Gly Lys Ala Phe Ile Gln Lys Ala Thr Leu Ser Met 
                725                 730                 735     


His Gln Ile Ile His Thr Gly Lys Lys Pro Tyr Ala Cys Thr Glu Cys 
            740                 745                 750         


Gln Lys Ala Phe Thr Asp Arg Ser Asn Leu Ile Lys His Gln Lys Met 
        755                 760                 765             


His Ser Gly Glu Lys Arg Tyr Lys Ala Ser Asp 
    770                 775                 


<210>  1424
<211>  576
<212>  PRT
<213>  Human

<400>  1424

Met Asp Asp Leu Lys Tyr Gly Val Tyr Pro Leu Lys Glu Ala Ser Gly 
1               5                   10                  15      


Cys Pro Gly Ala Glu Arg Asn Leu Leu Val Tyr Ser Tyr Phe Glu Lys 
            20                  25                  30          


Glu Thr Leu Thr Phe Arg Asp Val Ala Ile Glu Phe Ser Leu Glu Glu 
        35                  40                  45              


Trp Glu Cys Leu Asn Pro Ala Gln Gln Asn Leu Tyr Met Asn Val Met 
    50                  55                  60                  


Leu Glu Asn Tyr Lys Asn Leu Val Phe Leu Gly Val Ala Val Ser Lys 
65                  70                  75                  80  


Gln Asp Pro Val Thr Cys Leu Glu Gln Glu Lys Glu Pro Trp Asn Met 
                85                  90                  95      


Lys Arg His Glu Met Val Asp Glu Pro Pro Ala Met Cys Ser Tyr Phe 
            100                 105                 110         


Thr Lys Asp Leu Trp Pro Glu Gln Asp Ile Lys Asp Ser Phe Gln Gln 
        115                 120                 125             


Val Ile Leu Arg Arg Tyr Gly Lys Cys Glu His Glu Asn Leu Gln Leu 
    130                 135                 140                 


Arg Lys Gly Ser Ala Ser Val Asp Glu Tyr Lys Val His Lys Glu Gly 
145                 150                 155                 160 


Tyr Asn Glu Leu Asn Gln Cys Leu Thr Thr Thr Gln Ser Lys Ile Phe 
                165                 170                 175     


Pro Cys Asp Lys Tyr Val Lys Val Phe His Lys Phe Leu Asn Ala Asn 
            180                 185                 190         


Arg His Lys Thr Arg His Thr Gly Lys Lys Pro Phe Lys Cys Lys Lys 
        195                 200                 205             


Cys Gly Lys Ser Phe Cys Met Leu Leu His Leu Ser Gln His Lys Arg 
    210                 215                 220                 


Ile His Ile Arg Glu Asn Ser Tyr Gln Cys Glu Glu Cys Gly Lys Ala 
225                 230                 235                 240 


Phe Lys Trp Phe Ser Thr Leu Thr Arg His Lys Arg Ile His Thr Gly 
                245                 250                 255     


Glu Lys Pro Phe Lys Cys Glu Glu Cys Gly Lys Ala Phe Lys Gln Ser 
            260                 265                 270         


Ser Thr Leu Thr Thr His Lys Ile Ile His Thr Gly Glu Lys Pro Tyr 
        275                 280                 285             


Arg Cys Glu Glu Cys Gly Lys Ala Phe Asn Arg Ser Ser His Leu Thr 
    290                 295                 300                 


Thr His Lys Ile Ile His Thr Gly Glu Lys Pro Tyr Lys Cys Glu Glu 
305                 310                 315                 320 


Cys Gly Lys Ala Phe Asn Gln Ser Ser Thr Leu Ser Thr His Lys Phe 
                325                 330                 335     


Ile His Ala Gly Glu Lys Pro Tyr Lys Cys Glu Glu Cys Asp Lys Ala 
            340                 345                 350         


Phe Asn Arg Phe Ser Tyr Leu Thr Lys His Lys Ile Ile His Thr Gly 
        355                 360                 365             


Glu Lys Ser Tyr Lys Cys Glu Glu Cys Gly Lys Gly Phe Asn Trp Ser 
    370                 375                 380                 


Ser Thr Leu Thr Lys His Lys Arg Ile His Thr Gly Glu Lys Pro Tyr 
385                 390                 395                 400 


Lys Cys Glu Val Cys Gly Lys Ala Phe Asn Glu Ser Ser Asn Leu Thr 
                405                 410                 415     


Thr His Lys Met Ile His Thr Gly Glu Lys Pro Tyr Lys Cys Glu Glu 
            420                 425                 430         


Cys Gly Lys Ala Phe Asn Arg Ser Pro Gln Leu Thr Ala His Lys Ile 
        435                 440                 445             


Ile His Thr Gly Glu Lys Pro Tyr Lys Cys Glu Glu Cys Gly Lys Ala 
    450                 455                 460                 


Phe Ser Gln Ser Ser Ile Leu Thr Thr His Lys Arg Ile His Thr Gly 
465                 470                 475                 480 


Glu Lys Pro Tyr Lys Cys Glu Glu Cys Gly Lys Ala Phe Asn Arg Ser 
                485                 490                 495     


Ser Asn Leu Thr Lys His Lys Ile Ile His Thr Gly Glu Lys Ser Tyr 
            500                 505                 510         


Lys Cys Glu Glu Cys Gly Lys Ala Phe Asn Gln Ser Ser Thr Leu Thr 
        515                 520                 525             


Lys His Arg Lys Ile His Thr Arg Gln Lys Pro Tyr Asn Cys Glu Glu 
    530                 535                 540                 


Cys Asp Asn Thr Phe Asn Gln Ser Ser Asn Leu Ile Lys Gln Asn Asn 
545                 550                 555                 560 


Ser Tyr Trp Arg Glu Thr Leu Gln Met Ser Arg Met Trp Glu Ser Leu 
                565                 570                 575     


<210>  1425
<211>  276
<212>  PRT
<213>  Homo sapiens

<400>  1425

Met Ala Pro Pro Pro Ala Pro Leu Leu Ala Pro Arg Pro Gly Glu Thr 
1               5                   10                  15      


Arg Pro Gly Cys Arg Lys Pro Gly Thr Val Ser Phe Ala Asp Val Ala 
            20                  25                  30          


Val Tyr Phe Ser Pro Glu Glu Trp Gly Cys Leu Arg Pro Ala Gln Arg 
        35                  40                  45              


Ala Leu Tyr Arg Asp Val Met Gln Glu Thr Tyr Gly His Leu Gly Ala 
    50                  55                  60                  


Leu Gly Phe Pro Gly Pro Lys Pro Ala Leu Ile Ser Trp Met Glu Gln 
65                  70                  75                  80  


Glu Ser Glu Ala Trp Ser Pro Ala Ala Gln Asp Pro Glu Lys Gly Glu 
                85                  90                  95      


Arg Leu Gly Gly Ala Arg Arg Gly Asp Val Pro Asn Arg Lys Glu Glu 
            100                 105                 110         


Glu Pro Glu Glu Val Pro Arg Ala Lys Gly Pro Arg Lys Ala Pro Val 
        115                 120                 125             


Lys Glu Ser Pro Glu Val Leu Val Glu Arg Asn Pro Asp Pro Ala Ile 
    130                 135                 140                 


Ser Val Ala Pro Ala Arg Ala Gln Pro Pro Lys Asn Ala Ala Trp Asp 
145                 150                 155                 160 


Pro Thr Thr Gly Ala Gln Pro Pro Ala Pro Ile Pro Ser Met Asp Ala 
                165                 170                 175     


Gln Ala Gly Gln Arg Arg His Val Cys Thr Asp Cys Gly Arg Arg Phe 
            180                 185                 190         


Thr Tyr Pro Ser Leu Leu Val Ser His Arg Arg Met His Ser Gly Glu 
        195                 200                 205             


Arg Pro Phe Pro Cys Pro Glu Cys Gly Met Arg Phe Lys Arg Lys Phe 
    210                 215                 220                 


Ala Val Glu Ala His Gln Trp Ile His Arg Ser Cys Ser Gly Gly Arg 
225                 230                 235                 240 


Arg Gly Arg Arg Pro Gly Ile Arg Ala Val Pro Arg Ala Pro Val Arg 
                245                 250                 255     


Gly Asp Arg Asp Pro Pro Val Leu Phe Arg His Tyr Pro Asp Ile Phe 
            260                 265                 270         


Glu Glu Cys Gly 
        275     


<210>  1426
<211>  730
<212>  PRT
<213>  Homo sapiens

<400>  1426

Met Ala Ala Gly Val Glu Ala Ala Ala Glu Val Ala Ala Thr Glu Ile 
1               5                   10                  15      


Lys Met Glu Glu Glu Ser Gly Ala Pro Gly Val Pro Ser Gly Asn Gly 
            20                  25                  30          


Ala Pro Gly Pro Lys Gly Glu Gly Glu Arg Pro Ala Gln Asn Glu Lys 
        35                  40                  45              


Arg Lys Glu Lys Asn Ile Lys Arg Gly Gly Asn Arg Phe Glu Pro Tyr 
    50                  55                  60                  


Ala Asn Pro Thr Lys Arg Tyr Arg Ala Phe Ile Thr Asn Ile Pro Phe 
65                  70                  75                  80  


Asp Val Lys Trp Gln Ser Leu Lys Asp Leu Val Lys Glu Lys Val Gly 
                85                  90                  95      


Glu Val Thr Tyr Val Glu Leu Leu Met Asp Ala Glu Gly Lys Ser Arg 
            100                 105                 110         


Gly Cys Ala Val Val Glu Phe Lys Met Glu Glu Ser Met Lys Lys Ala 
        115                 120                 125             


Ala Glu Val Leu Asn Lys His Ser Leu Ser Gly Arg Pro Leu Lys Val 
    130                 135                 140                 


Lys Glu Asp Pro Asp Gly Glu His Ala Arg Arg Ala Met Gln Lys Val 
145                 150                 155                 160 


Met Ala Thr Thr Gly Gly Met Gly Met Gly Pro Gly Gly Pro Gly Met 
                165                 170                 175     


Ile Thr Ile Pro Pro Ser Ile Leu Asn Asn Pro Asn Ile Pro Asn Glu 
            180                 185                 190         


Ile Ile His Ala Leu Gln Ala Gly Arg Leu Gly Ser Thr Val Phe Val 
        195                 200                 205             


Ala Asn Leu Asp Tyr Lys Val Gly Trp Lys Lys Leu Lys Glu Val Phe 
    210                 215                 220                 


Ser Met Ala Gly Val Val Val Arg Ala Asp Ile Leu Glu Asp Lys Asp 
225                 230                 235                 240 


Gly Lys Ser Arg Gly Ile Gly Thr Val Thr Phe Glu Gln Ser Ile Glu 
                245                 250                 255     


Ala Val Gln Ala Ile Ser Met Phe Asn Gly Gln Leu Leu Phe Asp Arg 
            260                 265                 270         


Pro Met His Val Lys Met Asp Glu Arg Ala Leu Pro Lys Gly Asp Phe 
        275                 280                 285             


Phe Pro Pro Glu Arg Pro Gln Gln Leu Pro His Gly Leu Gly Gly Ile 
    290                 295                 300                 


Gly Met Gly Leu Gly Pro Gly Gly Gln Pro Ile Asp Ala Asn His Leu 
305                 310                 315                 320 


Asn Lys Gly Ile Gly Met Gly Asn Ile Gly Pro Ala Gly Met Gly Met 
                325                 330                 335     


Glu Gly Ile Gly Phe Gly Ile Asn Lys Met Gly Gly Met Glu Gly Pro 
            340                 345                 350         


Phe Gly Gly Gly Met Glu Asn Met Gly Arg Phe Gly Ser Gly Met Asn 
        355                 360                 365             


Met Gly Arg Ile Asn Glu Ile Leu Ser Asn Ala Leu Lys Arg Gly Glu 
    370                 375                 380                 


Ile Ile Ala Lys Gln Gly Gly Gly Gly Gly Gly Gly Ser Val Pro Gly 
385                 390                 395                 400 


Ile Glu Arg Met Gly Pro Gly Ile Asp Arg Leu Gly Gly Ala Gly Met 
                405                 410                 415     


Glu Arg Met Gly Ala Gly Leu Gly His Gly Met Asp Arg Val Gly Ser 
            420                 425                 430         


Glu Ile Glu Arg Met Gly Leu Val Met Asp Arg Met Gly Ser Val Glu 
        435                 440                 445             


Arg Met Gly Ser Gly Ile Glu Arg Met Gly Pro Leu Gly Leu Asp His 
    450                 455                 460                 


Met Ala Ser Ser Ile Glu Arg Met Gly Gln Thr Met Glu Arg Ile Gly 
465                 470                 475                 480 


Ser Gly Val Glu Arg Met Gly Ala Gly Met Gly Phe Gly Leu Glu Arg 
                485                 490                 495     


Met Ala Ala Pro Ile Asp Arg Val Gly Gln Thr Ile Glu Arg Met Gly 
            500                 505                 510         


Ser Gly Val Glu Arg Met Gly Pro Ala Ile Glu Arg Met Gly Leu Ser 
        515                 520                 525             


Met Glu Arg Met Val Pro Ala Gly Met Gly Ala Gly Leu Glu Arg Met 
    530                 535                 540                 


Gly Pro Val Met Asp Arg Met Ala Thr Gly Leu Glu Arg Met Gly Ala 
545                 550                 555                 560 


Asn Asn Leu Glu Arg Met Gly Leu Glu Arg Met Gly Ala Asn Ser Leu 
                565                 570                 575     


Glu Arg Met Gly Leu Glu Arg Met Gly Ala Asn Ser Leu Glu Arg Met 
            580                 585                 590         


Gly Pro Ala Met Gly Pro Ala Leu Gly Ala Gly Ile Glu Arg Met Gly 
        595                 600                 605             


Leu Ala Met Gly Gly Gly Gly Gly Ala Ser Phe Asp Arg Ala Ile Glu 
    610                 615                 620                 


Met Glu Arg Gly Asn Phe Gly Gly Ser Phe Ala Gly Ser Phe Gly Gly 
625                 630                 635                 640 


Ala Gly Gly His Ala Pro Gly Val Ala Arg Lys Ala Cys Gln Ile Phe 
                645                 650                 655     


Val Arg Asn Leu Pro Phe Asp Phe Thr Trp Lys Met Leu Lys Asp Lys 
            660                 665                 670         


Phe Asn Glu Cys Gly His Val Leu Tyr Ala Asp Ile Lys Met Glu Asn 
        675                 680                 685             


Gly Lys Ser Lys Gly Cys Gly Val Val Lys Phe Glu Ser Pro Glu Val 
    690                 695                 700                 


Ala Glu Arg Ala Cys Arg Met Met Asn Gly Met Lys Leu Ser Gly Arg 
705                 710                 715                 720 


Glu Ile Asp Val Arg Ile Asp Arg Asn Ala 
                725                 730 


<210>  1427
<211>  406
<212>  PRT
<213>  Homo sapiens

<400>  1427

Met Ala Asp Pro Lys Tyr Ala Asp Leu Pro Gly Ile Ala Arg Asn Glu 
1               5                   10                  15      


Pro Asp Val Tyr Glu Thr Ser Asp Leu Pro Glu Asp Asp Gln Ala Glu 
            20                  25                  30          


Phe Asp Ala Phe Ala Gln Glu Leu Glu Glu Leu Thr Ser Thr Ser Val 
        35                  40                  45              


Glu His Ile Ile Val Asn Pro Asn Ala Ala Tyr Asp Lys Phe Lys Asp 
    50                  55                  60                  


Lys Arg Val Gly Thr Lys Gly Leu Asp Phe Ser Asp Arg Ile Gly Lys 
65                  70                  75                  80  


Thr Lys Arg Thr Gly Tyr Glu Ser Gly Glu Tyr Glu Met Leu Gly Glu 
                85                  90                  95      


Gly Leu Gly Val Lys Glu Thr Pro Gln Gln Lys Tyr Gln Arg Leu Leu 
            100                 105                 110         


His Glu Val Gln Glu Leu Thr Thr Glu Val Glu Lys Ile Lys Thr Thr 
        115                 120                 125             


Val Lys Glu Ser Ala Thr Glu Glu Lys Leu Thr Pro Val Leu Leu Ala 
    130                 135                 140                 


Lys Gln Leu Ala Ala Leu Lys Gln Gln Leu Val Ala Ser His Leu Glu 
145                 150                 155                 160 


Lys Leu Leu Gly Pro Asp Ala Ala Ile Asn Leu Thr Asp Pro Asp Gly 
                165                 170                 175     


Ala Leu Ala Lys Arg Leu Leu Leu Gln Leu Glu Ala Thr Lys Asn Ser 
            180                 185                 190         


Lys Gly Gly Ser Gly Gly Lys Thr Thr Gly Thr Pro Pro Asp Ser Ser 
        195                 200                 205             


Leu Val Thr Tyr Glu Leu His Ser Arg Pro Glu Gln Asp Lys Phe Ser 
    210                 215                 220                 


Gln Ala Ala Lys Val Ala Glu Leu Glu Lys Arg Leu Thr Glu Leu Glu 
225                 230                 235                 240 


Thr Ala Val Arg Cys Asp Gln Asp Ala Gln Asn Pro Leu Ser Ala Gly 
                245                 250                 255     


Leu Gln Gly Ala Cys Leu Met Glu Thr Val Glu Leu Leu Gln Ala Lys 
            260                 265                 270         


Val Ser Ala Leu Asp Leu Ala Val Leu Asp Gln Val Glu Ala Arg Leu 
        275                 280                 285             


Gln Ser Val Leu Gly Lys Val Asn Glu Ile Ala Lys His Lys Ala Ser 
    290                 295                 300                 


Val Glu Asp Ala Asp Thr Gln Ser Lys Val His Gln Leu Tyr Glu Thr 
305                 310                 315                 320 


Ile Gln Arg Trp Ser Pro Ile Ala Ser Thr Leu Pro Glu Leu Val Gln 
                325                 330                 335     


Arg Leu Val Thr Ile Lys Gln Leu His Glu Gln Ala Met Gln Phe Gly 
            340                 345                 350         


Gln Leu Leu Thr His Leu Asp Thr Thr Gln Gln Met Ile Ala Asn Ser 
        355                 360                 365             


Leu Lys Asp Asn Thr Thr Leu Leu Thr Gln Val Gln Thr Thr Met Arg 
    370                 375                 380                 


Glu Asn Leu Ala Thr Val Glu Gly Asn Phe Ala Ser Ile Asp Glu Arg 
385                 390                 395                 400 


Met Lys Lys Leu Gly Lys 
                405     


<210>  1428
<211>  534
<212>  PRT
<213>  Homo sapiens

<400>  1428

Met Phe Ser Trp Val Ser Lys Asp Ala Arg Arg Lys Lys Glu Pro Glu 
1               5                   10                  15      


Leu Phe Gln Thr Val Ala Glu Gly Leu Arg Gln Leu Tyr Ala Gln Lys 
            20                  25                  30          


Leu Leu Pro Leu Glu Glu His Tyr Arg Phe His Glu Phe His Ser Pro 
        35                  40                  45              


Ala Leu Glu Asp Ala Asp Phe Asp Asn Lys Pro Met Val Leu Leu Val 
    50                  55                  60                  


Gly Gln Tyr Ser Thr Gly Lys Thr Thr Phe Ile Arg His Leu Ile Glu 
65                  70                  75                  80  


Gln Asp Phe Pro Gly Met Arg Ile Gly Pro Glu Pro Thr Thr Asp Ser 
                85                  90                  95      


Phe Ile Ala Val Met His Gly Pro Thr Glu Gly Val Val Pro Gly Asn 
            100                 105                 110         


Ala Leu Val Val Asp Pro Arg Arg Pro Phe Arg Lys Leu Asn Ala Phe 
        115                 120                 125             


Gly Asn Ala Phe Leu Asn Arg Phe Met Cys Ala Gln Leu Pro Asn Pro 
    130                 135                 140                 


Val Leu Asp Ser Ile Ser Ile Ile Asp Thr Pro Gly Ile Leu Ser Gly 
145                 150                 155                 160 


Glu Lys Gln Arg Ile Ser Arg Gly Tyr Asp Phe Ala Ala Val Leu Glu 
                165                 170                 175     


Trp Phe Ala Glu Arg Val Asp Arg Ile Ile Leu Leu Phe Asp Ala His 
            180                 185                 190         


Lys Leu Asp Ile Ser Asp Glu Phe Ser Glu Val Ile Lys Ala Leu Lys 
        195                 200                 205             


Asn His Glu Asp Lys Ile Arg Val Val Leu Asn Lys Ala Asp Gln Ile 
    210                 215                 220                 


Glu Thr Gln Gln Leu Met Arg Val Tyr Gly Ala Leu Met Trp Ser Leu 
225                 230                 235                 240 


Gly Lys Ile Ile Asn Thr Pro Glu Val Val Arg Val Tyr Ile Gly Ser 
                245                 250                 255     


Phe Trp Ser His Pro Leu Leu Ile Pro Asp Asn Arg Lys Leu Phe Glu 
            260                 265                 270         


Ala Glu Glu Gln Asp Leu Phe Lys Asp Ile Gln Ser Leu Pro Arg Asn 
        275                 280                 285             


Ala Ala Leu Arg Lys Leu Asn Asp Leu Ile Lys Arg Ala Arg Leu Ala 
    290                 295                 300                 


Lys Val His Ala Tyr Ile Ile Ser Ser Leu Lys Lys Glu Met Pro Asn 
305                 310                 315                 320 


Val Phe Gly Lys Glu Ser Lys Lys Lys Glu Leu Val Asn Asn Leu Gly 
                325                 330                 335     


Glu Ile Tyr Gln Lys Ile Glu Arg Glu His Gln Ile Ser Pro Gly Asp 
            340                 345                 350         


Phe Pro Ser Leu Arg Lys Met Gln Glu Leu Leu Gln Thr Gln Asp Phe 
        355                 360                 365             


Ser Lys Phe Gln Ala Leu Lys Pro Lys Leu Leu Asp Thr Val Asp Asp 
    370                 375                 380                 


Met Leu Ala Asn Asp Ile Ala Arg Leu Met Val Met Val Arg Gln Glu 
385                 390                 395                 400 


Glu Ser Leu Met Pro Ser Gln Val Val Lys Gly Gly Ala Phe Asp Gly 
                405                 410                 415     


Thr Met Asn Gly Pro Phe Gly His Gly Tyr Gly Glu Gly Ala Gly Glu 
            420                 425                 430         


Gly Ile Asp Asp Val Glu Trp Val Val Gly Lys Asp Lys Pro Thr Tyr 
        435                 440                 445             


Asp Glu Ile Phe Tyr Thr Leu Ser Pro Val Asn Gly Lys Ile Thr Gly 
    450                 455                 460                 


Ala Asn Ala Lys Lys Glu Met Val Lys Ser Lys Leu Pro Asn Thr Val 
465                 470                 475                 480 


Leu Gly Lys Ile Trp Lys Leu Ala Asp Val Asp Lys Asp Gly Leu Leu 
                485                 490                 495     


Asp Asp Glu Glu Phe Ala Leu Ala Asn His Leu Ile Lys Val Lys Leu 
            500                 505                 510         


Glu Gly His Glu Leu Pro Ala Asp Leu Pro Pro His Leu Val Pro Pro 
        515                 520                 525             


Ser Lys Arg Arg His Glu 
    530                 


<210>  1429
<211>  427
<212>  PRT
<213>  Homo sapiens

<400>  1429

Met Ala Val Leu Ala Ala Leu Leu Arg Ser Gly Ala Arg Ser Arg Ser 
1               5                   10                  15      


Pro Leu Leu Arg Arg Leu Val Gln Glu Ile Arg Tyr Val Glu Arg Ser 
            20                  25                  30          


Tyr Val Ser Lys Pro Thr Leu Lys Glu Val Val Ile Val Ser Ala Thr 
        35                  40                  45              


Arg Thr Pro Ile Gly Ser Phe Leu Gly Ser Leu Ser Leu Leu Pro Ala 
    50                  55                  60                  


Thr Lys Leu Gly Ser Ile Ala Ile Gln Gly Ala Ile Glu Lys Ala Gly 
65                  70                  75                  80  


Ile Pro Lys Glu Glu Val Lys Glu Ala Tyr Met Gly Asn Val Leu Gln 
                85                  90                  95      


Gly Gly Glu Gly Gln Ala Pro Thr Arg Gln Ala Val Leu Gly Ala Gly 
            100                 105                 110         


Leu Pro Ile Ser Thr Pro Cys Thr Thr Ile Asn Lys Val Cys Ala Ser 
        115                 120                 125             


Gly Met Lys Ala Ile Met Met Ala Ser Gln Ser Leu Met Cys Gly His 
    130                 135                 140                 


Gln Asp Val Met Val Ala Gly Gly Met Glu Ser Met Ser Asn Val Pro 
145                 150                 155                 160 


Tyr Val Met Asn Arg Gly Ser Thr Pro Tyr Gly Gly Val Lys Leu Glu 
                165                 170                 175     


Asp Leu Ile Val Lys Asp Gly Leu Thr Asp Val Tyr Asn Lys Ile His 
            180                 185                 190         


Met Gly Ser Cys Ala Glu Asn Thr Ala Lys Lys Leu Asn Ile Ala Arg 
        195                 200                 205             


Asn Glu Gln Asp Ala Tyr Ala Ile Asn Ser Tyr Thr Arg Ser Lys Ala 
    210                 215                 220                 


Ala Trp Glu Ala Gly Lys Phe Gly Asn Glu Val Ile Pro Val Thr Val 
225                 230                 235                 240 


Thr Val Lys Gly Gln Pro Asp Val Val Val Lys Glu Asp Glu Glu Tyr 
                245                 250                 255     


Lys Arg Val Asp Phe Ser Lys Val Pro Lys Leu Lys Thr Val Phe Gln 
            260                 265                 270         


Lys Glu Asn Gly Thr Val Thr Ala Ala Asn Ala Ser Thr Leu Asn Asp 
        275                 280                 285             


Gly Ala Ala Ala Leu Val Leu Met Thr Ala Asp Ala Ala Lys Arg Leu 
    290                 295                 300                 


Asn Val Thr Pro Leu Ala Arg Ile Val Ala Phe Ala Asp Ala Ala Val 
305                 310                 315                 320 


Glu Pro Ile Asp Phe Pro Ile Ala Pro Val Tyr Ala Ala Ser Met Val 
                325                 330                 335     


Leu Lys Asp Val Gly Leu Lys Lys Glu Asp Ile Ala Met Trp Glu Val 
            340                 345                 350         


Asn Glu Ala Phe Ser Leu Val Val Leu Ala Asn Ile Lys Met Leu Glu 
        355                 360                 365             


Ile Asp Pro Gln Lys Val Asn Ile Asn Gly Gly Ala Val Ser Leu Gly 
    370                 375                 380                 


His Pro Ile Gly Met Ser Gly Ala Arg Ile Val Gly His Leu Thr His 
385                 390                 395                 400 


Ala Leu Lys Gln Gly Glu Tyr Gly Leu Ala Ser Ile Cys Asn Gly Gly 
                405                 410                 415     


Gly Gly Ala Ser Ala Met Leu Ile Gln Lys Leu 
            420                 425         


<210>  1430
<211>  180
<212>  PRT
<213>  Homo sapiens

<400>  1430

Met Ala Ser Thr Ser Tyr Asp Tyr Cys Arg Val Pro Met Glu Asp Gly 
1               5                   10                  15      


Asp Lys Arg Cys Lys Leu Leu Leu Gly Ile Gly Ile Leu Val Leu Leu 
            20                  25                  30          


Ile Ile Val Ile Leu Gly Val Pro Leu Ile Ile Phe Thr Ile Lys Ala 
        35                  40                  45              


Asn Ser Glu Ala Cys Arg Asp Gly Leu Arg Ala Val Met Glu Cys Arg 
    50                  55                  60                  


Asn Val Thr His Leu Leu Gln Gln Glu Leu Thr Glu Ala Gln Lys Gly 
65                  70                  75                  80  


Phe Gln Asp Val Glu Ala Gln Ala Ala Thr Cys Asn His Thr Val Met 
                85                  90                  95      


Ala Leu Met Ala Ser Leu Asp Ala Glu Lys Ala Gln Gly Gln Lys Lys 
            100                 105                 110         


Val Glu Glu Leu Glu Gly Glu Ile Thr Thr Leu Asn His Lys Leu Gln 
        115                 120                 125             


Asp Ala Ser Ala Glu Val Glu Arg Leu Arg Arg Glu Asn Gln Val Leu 
    130                 135                 140                 


Ser Val Arg Ile Ala Asp Lys Lys Tyr Tyr Pro Ser Ser Gln Asp Ser 
145                 150                 155                 160 


Ser Ser Ala Ala Ala Pro Gln Leu Leu Ile Val Leu Leu Gly Leu Ser 
                165                 170                 175     


Ala Leu Leu Gln 
            180 


<210>  1431
<211>  114
<212>  PRT
<213>  Homo sapiens

<400>  1431

Met Gly Pro Arg Arg Arg Ser Arg Lys Pro Glu Ala Pro Arg Arg Arg 
1               5                   10                  15      


Ser Pro Ser Pro Thr Pro Thr Pro Gly Pro Ser Arg Arg Gly Pro Ser 
            20                  25                  30          


Leu Gly Ala Ser Ser His Gln His Ser Arg Arg Arg Gln Gly Trp Leu 
        35                  40                  45              


Lys Glu Ile Arg Lys Leu Gln Lys Ser Thr His Leu Leu Ile Arg Lys 
    50                  55                  60                  


Leu Pro Phe Ser Arg Leu Ala Ala Glu Ala Phe Leu Val His Leu Phe 
65                  70                  75                  80  


Glu Asp Ala Tyr Leu Leu Thr Leu His Ala Gly Arg Val Thr Leu Phe 
                85                  90                  95      


Pro Lys Asp Val Gln Leu Ala Arg Arg Ile Arg Gly Leu Glu Glu Gly 
            100                 105                 110         


Leu Gly 
        


<210>  1432
<211>  795
<212>  PRT
<213>  Homo sapiens

<400>  1432

Met Ser Lys Arg His Arg Leu Asp Leu Gly Glu Asp Tyr Pro Ser Gly 
1               5                   10                  15      


Lys Lys Arg Ala Gly Thr Asp Gly Lys Asp Arg Asp Arg Asp Arg Asp 
            20                  25                  30          


Arg Glu Asp Arg Ser Lys Asp Arg Asp Arg Glu Arg Asp Arg Gly Asp 
        35                  40                  45              


Arg Glu Arg Glu Arg Glu Lys Glu Lys Glu Lys Glu Leu Arg Ala Ser 
    50                  55                  60                  


Thr Asn Ala Met Leu Ile Ser Ala Gly Leu Pro Pro Leu Lys Ala Ser 
65                  70                  75                  80  


His Ser Ala His Ser Thr His Ser Ala His Ser Thr His Ser Thr His 
                85                  90                  95      


Ser Ala His Ser Thr His Ala Gly His Ala Gly His Thr Ser Leu Pro 
            100                 105                 110         


Gln Cys Ile Asn Pro Phe Thr Asn Leu Pro His Thr Pro Arg Tyr Tyr 
        115                 120                 125             


Asp Ile Leu Lys Lys Arg Leu Gln Leu Pro Val Trp Glu Tyr Lys Asp 
    130                 135                 140                 


Arg Phe Thr Asp Ile Leu Val Arg His Gln Ser Phe Val Leu Val Gly 
145                 150                 155                 160 


Glu Thr Gly Ser Gly Lys Thr Thr Gln Ile Pro Gln Trp Cys Val Glu 
                165                 170                 175     


Tyr Met Arg Ser Leu Pro Gly Pro Lys Arg Gly Val Ala Cys Thr Gln 
            180                 185                 190         


Pro Arg Arg Val Ala Ala Met Ser Val Ala Gln Arg Val Ala Asp Glu 
        195                 200                 205             


Met Asp Val Met Leu Gly Gln Glu Val Gly Tyr Ser Ile Arg Phe Glu 
    210                 215                 220                 


Asp Cys Ser Ser Ala Lys Thr Ile Leu Lys Tyr Met Thr Asp Gly Met 
225                 230                 235                 240 


Leu Leu Arg Glu Ala Met Asn Asp Pro Leu Leu Glu Arg Tyr Gly Val 
                245                 250                 255     


Ile Ile Leu Asp Glu Ala His Glu Arg Thr Leu Ala Thr Asp Ile Leu 
            260                 265                 270         


Met Gly Val Leu Lys Glu Val Val Arg Gln Arg Ser Asp Leu Lys Val 
        275                 280                 285             


Ile Val Met Ser Ala Thr Leu Asp Ala Gly Lys Phe Gln Ile Tyr Phe 
    290                 295                 300                 


Asp Asn Cys Pro Leu Leu Thr Ile Pro Gly Arg Thr His Pro Val Glu 
305                 310                 315                 320 


Ile Phe Tyr Thr Pro Glu Pro Glu Arg Asp Tyr Leu Glu Ala Ala Ile 
                325                 330                 335     


Arg Thr Val Ile Gln Ile His Met Cys Glu Glu Glu Glu Gly Asp Leu 
            340                 345                 350         


Leu Leu Phe Leu Thr Gly Gln Glu Glu Ile Asp Glu Ala Cys Lys Arg 
        355                 360                 365             


Ile Lys Arg Glu Val Asp Asp Leu Gly Pro Glu Val Gly Asp Ile Lys 
    370                 375                 380                 


Ile Ile Pro Leu Tyr Ser Thr Leu Pro Pro Gln Gln Gln Gln Arg Ile 
385                 390                 395                 400 


Phe Glu Pro Pro Pro Pro Lys Lys Gln Asn Gly Ala Ile Gly Arg Lys 
                405                 410                 415     


Val Val Val Ser Thr Asn Ile Ala Glu Thr Ser Leu Thr Ile Asp Gly 
            420                 425                 430         


Val Val Phe Val Ile Asp Pro Gly Phe Ala Lys Gln Lys Val Tyr Asn 
        435                 440                 445             


Pro Arg Ile Arg Val Glu Ser Leu Leu Val Thr Ala Ile Ser Lys Ala 
    450                 455                 460                 


Ser Ala Gln Gln Arg Ala Gly Arg Ala Gly Arg Thr Arg Pro Gly Lys 
465                 470                 475                 480 


Cys Phe Arg Leu Tyr Thr Glu Lys Ala Tyr Lys Thr Glu Met Gln Asp 
                485                 490                 495     


Asn Thr Tyr Pro Glu Ile Leu Arg Ser Asn Leu Gly Ser Val Val Leu 
            500                 505                 510         


Gln Leu Lys Lys Leu Gly Ile Asp Asp Leu Val His Phe Asp Phe Met 
        515                 520                 525             


Asp Pro Pro Ala Pro Glu Thr Leu Met Arg Ala Leu Glu Leu Leu Asn 
    530                 535                 540                 


Tyr Leu Ala Ala Leu Asn Asp Asp Gly Asp Leu Thr Glu Leu Gly Ser 
545                 550                 555                 560 


Met Met Ala Glu Phe Pro Leu Asp Pro Gln Leu Ala Lys Met Val Ile 
                565                 570                 575     


Ala Ser Cys Asp Tyr Asn Cys Ser Asn Glu Val Leu Ser Ile Thr Ala 
            580                 585                 590         


Met Leu Ser Val Pro Gln Cys Phe Val Arg Pro Thr Glu Ala Lys Lys 
        595                 600                 605             


Ala Ala Asp Glu Ala Lys Met Arg Phe Ala His Ile Asp Gly Asp His 
    610                 615                 620                 


Leu Thr Leu Leu Asn Val Tyr His Ala Phe Lys Gln Asn His Glu Ser 
625                 630                 635                 640 


Val Gln Trp Cys Tyr Asp Asn Phe Ile Asn Tyr Arg Ser Leu Met Ser 
                645                 650                 655     


Ala Asp Asn Val Arg Gln Gln Leu Ser Arg Ile Met Asp Arg Phe Asn 
            660                 665                 670         


Leu Pro Arg Arg Ser Thr Asp Phe Thr Ser Arg Asp Tyr Tyr Ile Asn 
        675                 680                 685             


Ile Arg Lys Ala Leu Val Thr Gly Tyr Phe Met Gln Val Ala His Leu 
    690                 695                 700                 


Glu Arg Thr Gly His Tyr Leu Thr Val Lys Asp Asn Gln Val Val Gln 
705                 710                 715                 720 


Leu His Pro Ser Thr Val Leu Asp His Lys Pro Glu Trp Val Leu Tyr 
                725                 730                 735     


Asn Glu Phe Val Leu Thr Thr Lys Asn Tyr Ile Arg Thr Cys Thr Asp 
            740                 745                 750         


Ile Lys Pro Glu Trp Leu Val Lys Ile Ala Pro Gln Tyr Tyr Asp Met 
        755                 760                 765             


Ser Asn Phe Pro Gln Cys Glu Ala Lys Arg Gln Leu Asp Arg Ile Ile 
    770                 775                 780                 


Ala Lys Leu Gln Ser Lys Glu Tyr Ser Gln Tyr 
785                 790                 795 


<210>  1433
<211>  1037
<212>  PRT
<213>  Homo sapiens

<400>  1433

Met Asp Arg Met Ala Ser Ser Met Lys Gln Val Pro Asn Pro Leu Pro 
1               5                   10                  15      


Lys Val Leu Ser Arg Arg Gly Val Gly Ala Gly Leu Glu Ala Ala Glu 
            20                  25                  30          


Arg Glu Ser Phe Glu Arg Thr Gln Thr Val Ser Ile Asn Lys Ala Ile 
        35                  40                  45              


Asn Thr Gln Glu Val Ala Val Lys Glu Lys His Ala Arg Thr Cys Ile 
    50                  55                  60                  


Leu Gly Thr His His Glu Lys Gly Ala Gln Thr Phe Trp Ser Val Val 
65                  70                  75                  80  


Asn Arg Leu Pro Leu Ser Ser Asn Ala Val Leu Cys Trp Lys Phe Cys 
                85                  90                  95      


His Val Phe His Lys Leu Leu Arg Asp Gly His Pro Asn Val Leu Lys 
            100                 105                 110         


Asp Ser Leu Arg Tyr Arg Asn Glu Leu Ser Asp Met Ser Arg Met Trp 
        115                 120                 125             


Gly His Leu Ser Glu Gly Tyr Gly Gln Leu Cys Ser Ile Tyr Leu Lys 
    130                 135                 140                 


Leu Leu Arg Thr Lys Met Glu Tyr His Thr Lys Asn Pro Arg Phe Pro 
145                 150                 155                 160 


Gly Asn Leu Gln Met Ser Asp Arg Gln Leu Asp Glu Ala Gly Glu Ser 
                165                 170                 175     


Asp Val Asn Asn Phe Phe Gln Leu Thr Val Glu Met Phe Asp Tyr Leu 
            180                 185                 190         


Glu Cys Glu Leu Asn Leu Phe Gln Thr Val Phe Asn Ser Leu Asp Met 
        195                 200                 205             


Ser Arg Ser Val Ser Val Thr Ala Ala Gly Gln Cys Arg Leu Ala Pro 
    210                 215                 220                 


Leu Ile Gln Val Ile Leu Asp Cys Ser His Leu Tyr Asp Tyr Thr Val 
225                 230                 235                 240 


Lys Leu Leu Phe Lys Leu His Ser Cys Leu Pro Ala Asp Thr Leu Gln 
                245                 250                 255     


Gly His Arg Asp Arg Phe Met Glu Gln Phe Thr Lys Leu Lys Asp Leu 
            260                 265                 270         


Phe Tyr Arg Ser Ser Asn Leu Gln Tyr Phe Lys Arg Leu Ile Gln Ile 
        275                 280                 285             


Pro Gln Leu Pro Glu Asn Pro Pro Asn Phe Leu Arg Ala Ser Ala Leu 
    290                 295                 300                 


Ser Glu His Ile Ser Pro Val Val Val Ile Pro Ala Glu Ala Ser Ser 
305                 310                 315                 320 


Pro Asp Ser Glu Pro Val Leu Glu Lys Asp Asp Leu Met Asp Met Asp 
                325                 330                 335     


Ala Ser Gln Gln Asn Leu Phe Asp Asn Lys Phe Asp Asp Ile Phe Gly 
            340                 345                 350         


Ser Ser Phe Ser Ser Asp Pro Phe Asn Phe Asn Ser Gln Asn Gly Val 
        355                 360                 365             


Asn Lys Asp Glu Lys Asp His Leu Ile Glu Arg Leu Tyr Arg Glu Ile 
    370                 375                 380                 


Ser Gly Leu Lys Ala Gln Leu Glu Asn Met Lys Thr Glu Ser Gln Arg 
385                 390                 395                 400 


Val Val Leu Gln Leu Lys Gly His Val Ser Glu Leu Glu Ala Asp Leu 
                405                 410                 415     


Ala Glu Gln Gln His Leu Arg Gln Gln Ala Ala Asp Asp Cys Glu Phe 
            420                 425                 430         


Leu Arg Ala Glu Leu Asp Glu Leu Arg Arg Gln Arg Glu Asp Thr Glu 
        435                 440                 445             


Lys Ala Gln Arg Ser Leu Ser Glu Ile Glu Arg Lys Ala Gln Ala Asn 
    450                 455                 460                 


Glu Gln Arg Tyr Ser Lys Leu Lys Glu Lys Tyr Ser Glu Leu Val Gln 
465                 470                 475                 480 


Asn His Ala Asp Leu Leu Arg Lys Asn Ala Glu Val Thr Lys Gln Val 
                485                 490                 495     


Ser Met Ala Arg Gln Ala Gln Val Asp Leu Glu Arg Glu Lys Lys Glu 
            500                 505                 510         


Leu Glu Asp Ser Leu Glu Arg Ile Ser Asp Gln Gly Gln Arg Lys Thr 
        515                 520                 525             


Gln Glu Gln Leu Glu Val Leu Glu Ser Leu Lys Gln Glu Leu Ala Thr 
    530                 535                 540                 


Ser Gln Arg Glu Leu Gln Val Leu Gln Gly Ser Leu Glu Thr Ser Ala 
545                 550                 555                 560 


Gln Ser Glu Ala Asn Trp Ala Ala Glu Phe Ala Glu Leu Glu Lys Glu 
                565                 570                 575     


Arg Asp Ser Leu Val Ser Gly Ala Ala His Arg Glu Glu Glu Leu Ser 
            580                 585                 590         


Ala Leu Arg Lys Glu Leu Gln Asp Thr Gln Leu Lys Leu Ala Ser Thr 
        595                 600                 605             


Glu Glu Ser Met Cys Gln Leu Ala Lys Asp Gln Arg Lys Met Leu Leu 
    610                 615                 620                 


Val Gly Ser Arg Lys Ala Ala Glu Gln Val Ile Gln Asp Ala Leu Asn 
625                 630                 635                 640 


Gln Leu Glu Glu Pro Pro Leu Ile Ser Cys Ala Gly Ser Ala Asp His 
                645                 650                 655     


Leu Leu Ser Thr Val Thr Ser Ile Ser Ser Cys Ile Glu Gln Leu Glu 
            660                 665                 670         


Lys Ser Trp Ser Gln Tyr Leu Ala Cys Pro Glu Asp Ile Ser Gly Leu 
        675                 680                 685             


Leu His Ser Ile Thr Leu Leu Ala His Leu Thr Ser Asp Ala Ile Ala 
    690                 695                 700                 


His Gly Ala Thr Thr Cys Leu Arg Ala Pro Pro Glu Pro Ala Asp Ser 
705                 710                 715                 720 


Leu Thr Glu Ala Cys Lys Gln Tyr Gly Arg Glu Thr Leu Ala Tyr Leu 
                725                 730                 735     


Ala Ser Leu Glu Glu Glu Gly Ser Leu Glu Asn Ala Asp Ser Thr Ala 
            740                 745                 750         


Met Arg Asn Cys Leu Ser Lys Ile Lys Ala Ile Gly Glu Glu Leu Leu 
        755                 760                 765             


Pro Arg Gly Leu Asp Ile Lys Gln Glu Glu Leu Gly Asp Leu Val Asp 
    770                 775                 780                 


Lys Glu Met Ala Ala Thr Ser Ala Ala Ile Glu Thr Ala Thr Ala Arg 
785                 790                 795                 800 


Ile Glu Glu Met Leu Ser Lys Ser Arg Ala Gly Asp Thr Gly Val Lys 
                805                 810                 815     


Leu Glu Val Asn Glu Arg Ile Leu Gly Cys Cys Thr Ser Leu Met Gln 
            820                 825                 830         


Ala Ile Gln Val Leu Ile Val Ala Ser Lys Asp Leu Gln Arg Glu Ile 
        835                 840                 845             


Val Glu Ser Gly Arg Gly Thr Ala Ser Pro Lys Glu Phe Tyr Ala Lys 
    850                 855                 860                 


Asn Ser Arg Trp Thr Glu Gly Leu Ile Ser Ala Ser Lys Ala Val Gly 
865                 870                 875                 880 


Trp Gly Ala Thr Val Met Val Asp Ala Ala Asp Leu Val Val Gln Gly 
                885                 890                 895     


Arg Gly Lys Phe Glu Glu Leu Met Val Cys Ser His Glu Ile Ala Ala 
            900                 905                 910         


Ser Thr Ala Gln Leu Val Ala Ala Ser Lys Val Lys Ala Asp Lys Asp 
        915                 920                 925             


Ser Pro Asn Leu Ala Gln Leu Gln Gln Ala Ser Arg Gly Val Asn Gln 
    930                 935                 940                 


Ala Thr Ala Gly Val Val Ala Ser Thr Ile Ser Gly Lys Ser Gln Ile 
945                 950                 955                 960 


Glu Glu Thr Asp Asn Met Asp Phe Ser Ser Met Thr Leu Thr Gln Ile 
                965                 970                 975     


Lys Arg Gln Glu Met Asp Ser Gln Val Arg Val Leu Glu Leu Glu Asn 
            980                 985                 990         


Glu Leu Gln Lys Glu Arg Gln Lys  Leu Gly Glu Leu Arg  Lys Lys His 
        995                 1000                 1005             


Tyr Glu  Leu Ala Gly Val Ala  Glu Gly Trp Glu Glu  Gly Thr Glu 
    1010                 1015                 1020             


Ala Ser  Pro Pro Thr Leu Gln  Glu Val Val Thr Glu  Lys Glu 
    1025                 1030                 1035         


<210>  1434
<211>  102
<212>  PRT
<213>  Homo sapiens

<400>  1434

Met Ala Gly Gln Ala Phe Arg Lys Phe Leu Pro Leu Phe Asp Arg Val 
1               5                   10                  15      


Leu Val Glu Arg Ser Ala Ala Glu Thr Val Thr Lys Gly Gly Ile Met 
            20                  25                  30          


Leu Pro Glu Lys Ser Gln Gly Lys Val Leu Gln Ala Thr Val Val Ala 
        35                  40                  45              


Val Gly Ser Gly Ser Lys Gly Lys Gly Gly Glu Ile Gln Pro Val Ser 
    50                  55                  60                  


Val Lys Val Gly Asp Lys Val Leu Leu Pro Glu Tyr Gly Gly Thr Lys 
65                  70                  75                  80  


Val Val Leu Asp Asp Lys Asp Tyr Phe Leu Phe Arg Asp Gly Asp Ile 
                85                  90                  95      


Leu Gly Lys Tyr Val Asp 
            100         


<210>  1435
<211>  500
<212>  PRT
<213>  Homo sapiens

<400>  1435

Met Ala Thr Ala Ala Ser Asn Pro Tyr Leu Pro Gly Asn Ser Leu Leu 
1               5                   10                  15      


Ala Ala Gly Ser Ile Val His Ser Asp Ala Ala Gly Ala Gly Gly Gly 
            20                  25                  30          


Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Ala Gly Gly Gly Gly 
        35                  40                  45              


Gly Gly Met Gln Pro Gly Ser Ala Ala Val Thr Ser Gly Ala Tyr Arg 
    50                  55                  60                  


Gly Asp Pro Ser Ser Val Lys Met Val Gln Ser Asp Phe Met Gln Gly 
65                  70                  75                  80  


Ala Met Ala Ala Ser Asn Gly Gly His Met Leu Ser His Ala His Gln 
                85                  90                  95      


Trp Val Thr Ala Leu Pro His Ala Ala Ala Ala Ala Ala Ala Ala Ala 
            100                 105                 110         


Ala Ala Ala Val Glu Ala Ser Ser Pro Trp Ser Gly Ser Ala Val Gly 
        115                 120                 125             


Met Ala Gly Ser Pro Gln Gln Pro Pro Gln Pro Pro Pro Pro Pro Pro 
    130                 135                 140                 


Gln Gly Pro Asp Val Lys Gly Gly Ala Gly Arg Asp Asp Leu His Ala 
145                 150                 155                 160 


Gly Thr Ala Leu His His Arg Gly Pro Pro His Leu Gly Pro Pro Pro 
                165                 170                 175     


Pro Pro Pro His Gln Gly His Pro Gly Gly Trp Gly Ala Ala Ala Ala 
            180                 185                 190         


Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala His Leu Pro Ser 
        195                 200                 205             


Met Ala Gly Gly Gln Gln Pro Pro Pro Gln Ser Leu Leu Tyr Ser Gln 
    210                 215                 220                 


Pro Gly Gly Phe Thr Val Asn Gly Met Leu Ser Ala Pro Pro Gly Pro 
225                 230                 235                 240 


Gly Gly Gly Gly Gly Gly Ala Gly Gly Gly Ala Gln Ser Leu Val His 
                245                 250                 255     


Pro Gly Leu Val Arg Gly Asp Thr Pro Glu Leu Ala Glu His His His 
            260                 265                 270         


His His His His His Ala His Pro His Pro Pro His Pro His His Ala 
        275                 280                 285             


Gln Gly Pro Pro His His Gly Gly Gly Gly Gly Gly Ala Gly Pro Gly 
    290                 295                 300                 


Leu Asn Ser His Asp Pro His Ser Asp Glu Asp Thr Pro Thr Ser Asp 
305                 310                 315                 320 


Asp Leu Glu Gln Phe Ala Lys Gln Phe Lys Gln Arg Arg Ile Lys Leu 
                325                 330                 335     


Gly Phe Thr Gln Ala Asp Val Gly Leu Ala Leu Gly Thr Leu Tyr Gly 
            340                 345                 350         


Asn Val Phe Ser Gln Thr Thr Ile Cys Arg Phe Glu Ala Leu Gln Leu 
        355                 360                 365             


Ser Phe Lys Asn Met Cys Lys Leu Lys Pro Leu Leu Asn Lys Trp Leu 
    370                 375                 380                 


Glu Glu Ala Asp Ser Ser Thr Gly Ser Pro Thr Ser Ile Asp Lys Ile 
385                 390                 395                 400 


Ala Ala Gln Gly Arg Lys Arg Lys Lys Arg Thr Ser Ile Glu Val Ser 
                405                 410                 415     


Val Lys Gly Ala Leu Glu Ser His Phe Leu Lys Cys Pro Lys Pro Ser 
            420                 425                 430         


Ala Gln Glu Ile Thr Asn Leu Ala Asp Ser Leu Gln Leu Glu Lys Glu 
        435                 440                 445             


Val Val Arg Val Trp Phe Cys Asn Arg Arg Gln Lys Glu Lys Arg Met 
    450                 455                 460                 


Thr Pro Pro Gly Ile Gln Gln Gln Thr Pro Asp Asp Val Tyr Ser Gln 
465                 470                 475                 480 


Val Gly Thr Val Ser Ala Asp Thr Pro Pro Pro His His Gly Leu Gln 
                485                 490                 495     


Thr Ser Val Gln 
            500 


<210>  1436
<211>  294
<212>  PRT
<213>  Homo sapiens

<400>  1436

Met Gln Pro Arg Arg Gln Arg Leu Pro Ala Pro Trp Ser Gly Pro Arg 
1               5                   10                  15      


Gly Pro Arg Pro Thr Ala Pro Leu Leu Ala Leu Leu Leu Leu Leu Ala 
            20                  25                  30          


Pro Val Ala Ala Pro Ala Gly Ser Gly Asp Pro Asp Asp Pro Gly Gln 
        35                  40                  45              


Pro Gln Asp Ala Gly Val Pro Arg Arg Leu Leu Gln Gln Ala Ala Arg 
    50                  55                  60                  


Ala Ala Leu His Phe Phe Asn Phe Arg Ser Gly Ser Pro Ser Ala Leu 
65                  70                  75                  80  


Arg Val Leu Ala Glu Val Gln Glu Gly Arg Ala Trp Ile Asn Pro Lys 
                85                  90                  95      


Glu Gly Cys Lys Val His Val Val Phe Ser Thr Glu Arg Tyr Asn Pro 
            100                 105                 110         


Glu Ser Leu Leu Gln Glu Gly Glu Gly Arg Leu Gly Lys Cys Ser Ala 
        115                 120                 125             


Arg Val Phe Phe Lys Asn Gln Lys Pro Arg Pro Thr Ile Asn Val Thr 
    130                 135                 140                 


Cys Thr Arg Leu Ile Glu Lys Lys Lys Arg Gln Gln Glu Asp Tyr Leu 
145                 150                 155                 160 


Leu Tyr Lys Gln Met Lys Gln Leu Lys Asn Pro Leu Glu Ile Val Ser 
                165                 170                 175     


Ile Pro Asp Asn His Gly His Ile Asp Pro Ser Leu Arg Leu Ile Trp 
            180                 185                 190         


Asp Leu Ala Phe Leu Gly Ser Ser Tyr Val Met Trp Glu Met Thr Thr 
        195                 200                 205             


Gln Val Ser His Tyr Tyr Leu Ala Gln Leu Thr Ser Val Arg Gln Trp 
    210                 215                 220                 


Lys Thr Asn Asp Asp Thr Ile Asp Phe Asp Tyr Thr Val Leu Leu His 
225                 230                 235                 240 


Glu Leu Ser Thr Gln Glu Ile Ile Pro Cys Arg Ile His Leu Val Trp 
                245                 250                 255     


Tyr Pro Gly Lys Pro Leu Lys Val Lys Tyr His Cys Gln Glu Leu Gln 
            260                 265                 270         


Thr Pro Glu Glu Ala Ser Gly Thr Glu Glu Gly Ser Ala Val Val Pro 
        275                 280                 285             


Thr Glu Leu Ser Asn Phe 
    290                 


<210>  1437
<211>  165
<212>  PRT
<213>  Homo sapiens

<400>  1437

Met Pro Pro Lys Phe Asp Pro Asn Glu Ile Lys Val Val Tyr Leu Arg 
1               5                   10                  15      


Cys Thr Gly Gly Glu Val Gly Ala Thr Ser Ala Leu Ala Pro Lys Ile 
            20                  25                  30          


Gly Pro Leu Gly Leu Ser Pro Lys Lys Val Gly Asp Asp Ile Ala Lys 
        35                  40                  45              


Ala Thr Gly Asp Trp Lys Gly Leu Arg Ile Thr Val Lys Leu Thr Ile 
    50                  55                  60                  


Gln Asn Arg Gln Ala Gln Ile Glu Val Val Pro Ser Ala Ser Ala Leu 
65                  70                  75                  80  


Ile Ile Lys Ala Leu Lys Glu Pro Pro Arg Asp Arg Lys Lys Gln Lys 
                85                  90                  95      


Asn Ile Lys His Ser Gly Asn Ile Thr Phe Asp Glu Ile Val Asn Ile 
            100                 105                 110         


Ala Arg Gln Met Arg His Arg Ser Leu Ala Arg Glu Leu Ser Gly Thr 
        115                 120                 125             


Ile Lys Glu Ile Leu Gly Thr Ala Gln Ser Val Gly Cys Asn Val Asp 
    130                 135                 140                 


Gly Arg His Pro His Asp Ile Ile Asp Asp Ile Asn Ser Gly Ala Val 
145                 150                 155                 160 


Glu Cys Pro Ala Ser 
                165 


<210>  1438
<211>  282
<212>  PRT
<213>  Homo sapiens

<400>  1438

Met Ala Val Pro Glu Thr Arg Pro Asn His Thr Ile Tyr Ile Asn Asn 
1               5                   10                  15      


Leu Asn Glu Lys Ile Lys Lys Asp Glu Leu Lys Lys Ser Leu Tyr Ala 
            20                  25                  30          


Ile Phe Ser Gln Phe Gly Gln Ile Leu Asp Ile Leu Val Ser Arg Ser 
        35                  40                  45              


Leu Lys Met Arg Gly Gln Ala Phe Val Ile Phe Lys Glu Val Ser Ser 
    50                  55                  60                  


Ala Thr Asn Ala Leu Arg Ser Met Gln Gly Phe Pro Phe Tyr Asp Lys 
65                  70                  75                  80  


Pro Met Arg Ile Gln Tyr Ala Lys Thr Asp Ser Asp Ile Ile Ala Lys 
                85                  90                  95      


Met Lys Gly Thr Phe Val Glu Arg Asp Arg Lys Arg Glu Lys Arg Lys 
            100                 105                 110         


Pro Lys Ser Gln Glu Thr Pro Ala Thr Lys Lys Ala Val Gln Gly Gly 
        115                 120                 125             


Gly Ala Thr Pro Val Val Gly Ala Val Gln Gly Pro Val Pro Gly Met 
    130                 135                 140                 


Pro Pro Met Thr Gln Ala Pro Arg Ile Met His His Met Pro Gly Gln 
145                 150                 155                 160 


Pro Pro Tyr Met Pro Pro Pro Gly Met Ile Pro Pro Pro Gly Leu Ala 
                165                 170                 175     


Pro Gly Gln Ile Pro Pro Gly Ala Met Pro Pro Gln Gln Leu Met Pro 
            180                 185                 190         


Gly Gln Met Pro Pro Ala Gln Pro Leu Ser Glu Asn Pro Pro Asn His 
        195                 200                 205             


Ile Leu Phe Leu Thr Asn Leu Pro Glu Glu Thr Asn Glu Leu Met Leu 
    210                 215                 220                 


Ser Met Leu Phe Asn Gln Phe Pro Gly Phe Lys Glu Val Arg Leu Val 
225                 230                 235                 240 


Pro Gly Arg His Asp Ile Ala Phe Val Glu Phe Asp Asn Glu Val Gln 
                245                 250                 255     


Ala Gly Ala Ala Arg Asp Ala Leu Gln Gly Phe Lys Ile Thr Gln Asn 
            260                 265                 270         


Asn Ala Met Lys Ile Ser Phe Ala Lys Lys 
        275                 280         


<210>  1439
<211>  159
<212>  PRT
<213>  Homo sapiens

<400>  1439

Met Pro Lys Phe Tyr Cys Asp Tyr Cys Asp Thr Tyr Leu Thr His Asp 
1               5                   10                  15      


Ser Pro Ser Val Arg Lys Thr His Cys Ser Gly Arg Lys His Lys Glu 
            20                  25                  30          


Asn Val Lys Asp Tyr Tyr Gln Lys Trp Met Glu Glu Gln Ala Gln Ser 
        35                  40                  45              


Leu Ile Asp Lys Thr Thr Ala Ala Phe Gln Gln Gly Lys Ile Pro Pro 
    50                  55                  60                  


Thr Pro Phe Ser Ala Pro Pro Pro Ala Gly Ala Met Ile Pro Pro Pro 
65                  70                  75                  80  


Pro Ser Leu Pro Gly Pro Pro Arg Pro Gly Met Met Pro Ala Pro His 
                85                  90                  95      


Met Gly Gly Pro Pro Met Met Pro Met Met Gly Pro Pro Pro Pro Gly 
            100                 105                 110         


Met Met Pro Val Gly Pro Ala Pro Gly Met Arg Pro Pro Met Gly Gly 
        115                 120                 125             


His Met Pro Met Met Pro Gly Pro Pro Met Met Arg Pro Pro Ala Arg 
    130                 135                 140                 


Pro Met Met Val Pro Thr Arg Pro Gly Met Thr Arg Pro Asp Arg 
145                 150                 155                 


<210>  1440
<211>  214
<212>  PRT
<213>  Homo sapiens

<400>  1440

Met Asn Gly Asp Asp Ala Phe Ala Arg Arg Pro Thr Val Gly Ala Gln 
1               5                   10                  15      


Ile Pro Glu Lys Ile Gln Lys Ala Phe Asp Asp Ile Ala Lys Tyr Phe 
            20                  25                  30          


Ser Lys Glu Glu Trp Glu Lys Met Lys Ala Ser Glu Lys Ile Phe Tyr 
        35                  40                  45              


Val Tyr Met Lys Arg Lys Tyr Glu Ala Met Thr Lys Leu Gly Phe Lys 
    50                  55                  60                  


Ala Thr Leu Pro Pro Phe Met Cys Asn Lys Arg Ala Glu Asp Phe Gln 
65                  70                  75                  80  


Gly Asn Asp Leu Asp Asn Asp Pro Asn Arg Gly Asn Gln Val Glu Arg 
                85                  90                  95      


Pro Gln Met Thr Phe Gly Arg Leu Gln Gly Ile Ser Pro Lys Ile Met 
            100                 105                 110         


Pro Lys Lys Pro Ala Glu Glu Gly Asn Asp Ser Glu Glu Val Pro Glu 
        115                 120                 125             


Ala Ser Gly Pro Gln Asn Asp Gly Lys Glu Leu Cys Pro Pro Gly Lys 
    130                 135                 140                 


Pro Thr Thr Ser Glu Lys Ile His Glu Arg Ser Gly Asn Arg Glu Ala 
145                 150                 155                 160 


Gln Glu Lys Glu Glu Arg Arg Gly Thr Ala His Arg Trp Ser Ser Gln 
                165                 170                 175     


Asn Thr His Asn Ile Gly Pro Lys Arg Gly Glu His Ala Trp Thr His 
            180                 185                 190         


Arg Leu Arg Glu Arg Lys Gln Leu Val Ile Tyr Glu Glu Ile Ser Asp 
        195                 200                 205             


Pro Glu Glu Asp Asp Glu 
    210                 


<210>  1441
<211>  759
<212>  PRT
<213>  Homo sapiens

<400>  1441

Met Glu Ala Val Ile Glu Lys Glu Cys Ser Ala Leu Gly Gly Leu Phe 
1               5                   10                  15      


Gln Thr Ile Ile Ser Asp Met Lys Gly Ser Tyr Pro Val Trp Glu Asp 
            20                  25                  30          


Phe Ile Asn Lys Ala Gly Lys Leu Gln Ser Gln Leu Arg Thr Thr Val 
        35                  40                  45              


Val Ala Ala Ala Ala Phe Leu Asp Ala Phe Gln Lys Val Ala Asp Met 
    50                  55                  60                  


Ala Thr Asn Thr Arg Gly Gly Thr Arg Glu Ile Gly Ser Ala Leu Thr 
65                  70                  75                  80  


Arg Met Cys Met Arg His Arg Ser Ile Glu Ala Lys Leu Arg Gln Phe 
                85                  90                  95      


Ser Ser Ala Leu Ile Asp Cys Leu Ile Asn Pro Leu Gln Glu Gln Met 
            100                 105                 110         


Glu Glu Trp Lys Lys Val Ala Asn Gln Leu Asp Lys Asp His Ala Lys 
        115                 120                 125             


Glu Tyr Lys Lys Ala Arg Gln Glu Ile Lys Lys Lys Ser Ser Asp Thr 
    130                 135                 140                 


Leu Lys Leu Gln Lys Lys Ala Lys Lys Val Asp Thr Leu Gly Arg Gly 
145                 150                 155                 160 


Asp Ile Gln Pro Gln Leu Asp Ser Ala Leu Gln Asp Val Asn Asp Lys 
                165                 170                 175     


Tyr Leu Leu Leu Glu Glu Thr Glu Lys Gln Ala Val Arg Lys Ala Leu 
            180                 185                 190         


Ile Glu Glu Arg Gly Arg Phe Cys Thr Phe Ile Ser Met Leu Arg Pro 
        195                 200                 205             


Val Ile Glu Glu Glu Ile Ser Met Leu Gly Glu Ile Thr His Leu Gln 
    210                 215                 220                 


Thr Ile Ser Glu Asp Leu Lys Ser Leu Thr Met Asp Pro His Lys Leu 
225                 230                 235                 240 


Pro Ser Ser Ser Glu Gln Val Ile Leu Asp Leu Lys Gly Ser Asp Tyr 
                245                 250                 255     


Ser Trp Ser Tyr Gln Thr Pro Pro Ser Ser Pro Ser Thr Thr Met Ser 
            260                 265                 270         


Arg Lys Ser Ser Val Cys Ser Ser Leu Asn Ser Val Asn Ser Ser Asp 
        275                 280                 285             


Ser Arg Ser Ser Gly Ser His Ser His Ser Pro Ser Ser His Tyr Arg 
    290                 295                 300                 


Tyr Arg Ser Ser Asn Leu Ala Gln Gln Ala Pro Val Arg Leu Ser Ser 
305                 310                 315                 320 


Val Ser Ser His Asp Ser Gly Phe Ile Ser Gln Asp Ala Phe Gln Ser 
                325                 330                 335     


Lys Ser Pro Ser Pro Met Pro Pro Glu Ala Pro Asn Gln Leu Ser Asn 
            340                 345                 350         


Gly Phe Ser His Tyr Ser Leu Ser Ser Glu Ser His Val Gly Pro Thr 
        355                 360                 365             


Gly Ala Gly Leu Phe Pro His Cys Leu Pro Ala Ser Arg Leu Leu Pro 
    370                 375                 380                 


Arg Val Thr Ser Val His Leu Pro Asp Tyr Ala His Tyr Tyr Thr Ile 
385                 390                 395                 400 


Gly Pro Gly Met Phe Pro Ser Ser Gln Ile Pro Ser Trp Lys Asp Trp 
                405                 410                 415     


Ala Lys Pro Gly Pro Tyr Asp Gln Pro Leu Val Asn Thr Leu Gln Arg 
            420                 425                 430         


Arg Lys Glu Lys Arg Glu Pro Asp Pro Asn Gly Gly Gly Pro Thr Thr 
        435                 440                 445             


Ala Ser Gly Pro Pro Ala Ala Ala Glu Glu Ala Gln Arg Pro Arg Ser 
    450                 455                 460                 


Met Thr Val Ser Ala Ala Thr Arg Pro Gly Glu Glu Met Glu Ala Cys 
465                 470                 475                 480 


Glu Glu Leu Ala Leu Ala Leu Ser Arg Gly Leu Gln Leu Asp Thr Gln 
                485                 490                 495     


Arg Ser Ser Arg Asp Ser Leu Gln Cys Ser Ser Gly Tyr Ser Thr Gln 
            500                 505                 510         


Thr Thr Thr Pro Cys Cys Ser Glu Asp Thr Ile Pro Ser Gln Val Ser 
        515                 520                 525             


Asp Tyr Asp Tyr Phe Ser Val Ser Gly Asp Gln Glu Ala Asp Gln Gln 
    530                 535                 540                 


Glu Phe Asp Lys Ser Ser Thr Ile Pro Arg Asn Ser Asp Ile Ser Gln 
545                 550                 555                 560 


Ser Tyr Arg Arg Met Phe Gln Ala Lys Arg Pro Ala Ser Thr Ala Gly 
                565                 570                 575     


Leu Pro Thr Thr Leu Gly Pro Ala Met Val Thr Pro Gly Val Ala Thr 
            580                 585                 590         


Ile Arg Arg Thr Pro Ser Thr Lys Pro Ser Val Arg Arg Gly Thr Ile 
        595                 600                 605             


Gly Ala Gly Pro Ile Pro Ile Lys Thr Pro Val Ile Pro Val Lys Thr 
    610                 615                 620                 


Pro Thr Val Pro Asp Leu Pro Gly Val Leu Pro Ala Pro Pro Asp Gly 
625                 630                 635                 640 


Pro Glu Glu Arg Gly Glu His Ser Pro Glu Ser Pro Ser Val Gly Glu 
                645                 650                 655     


Gly Pro Gln Gly Val Thr Ser Met Pro Ser Ser Met Trp Ser Gly Gln 
            660                 665                 670         


Ala Ser Val Asn Pro Pro Leu Pro Gly Pro Lys Pro Ser Ile Pro Glu 
        675                 680                 685             


Glu His Arg Gln Ala Ile Pro Glu Ser Glu Ala Glu Asp Gln Glu Arg 
    690                 695                 700                 


Glu Pro Pro Ser Ala Thr Val Ser Pro Gly Gln Ile Pro Glu Ser Asp 
705                 710                 715                 720 


Pro Ala Asp Leu Ser Pro Arg Asp Thr Pro Gln Gly Glu Asp Met Leu 
                725                 730                 735     


Asn Ala Ile Arg Arg Gly Val Lys Leu Lys Lys Thr Thr Thr Asn Asp 
            740                 745                 750         


Arg Ser Ala Pro Arg Phe Ser 
        755                 


<210>  1442
<211>  313
<212>  PRT
<213>  Homo sapiens

<400>  1442

Met Gly Ala Glu Ala Ser Ser Ser Trp Cys Pro Gly Thr Ala Leu Pro 
1               5                   10                  15      


Glu Glu Arg Leu Ser Val Lys Arg Ala Ser Glu Ile Ser Gly Phe Leu 
            20                  25                  30          


Gly Gln Gly Ser Ser Gly Glu Ala Ala Leu Asp Val Leu Thr His Val 
        35                  40                  45              


Leu Glu Gly Ala Gly Asn Lys Leu Thr Ser Ser Cys Gly Lys Pro Ser 
    50                  55                  60                  


Ser Asn Arg Met Ser Leu Gln Trp Thr Ala Val Ala Thr Phe Leu Tyr 
65                  70                  75                  80  


Ala Glu Val Phe Val Val Leu Leu Leu Cys Ile Pro Phe Ile Ser Pro 
                85                  90                  95      


Lys Arg Trp Gln Lys Ile Phe Lys Ser Arg Leu Val Glu Leu Leu Val 
            100                 105                 110         


Ser Tyr Gly Asn Thr Phe Phe Val Val Leu Ile Val Ile Leu Val Leu 
        115                 120                 125             


Leu Val Ile Asp Ala Val Arg Glu Ile Arg Lys Tyr Asp Asp Val Thr 
    130                 135                 140                 


Glu Lys Val Asn Leu Gln Asn Asn Pro Gly Ala Met Glu His Phe His 
145                 150                 155                 160 


Met Lys Leu Phe Arg Ala Gln Arg Asn Leu Tyr Ile Ala Gly Phe Ser 
                165                 170                 175     


Leu Leu Leu Ser Phe Leu Leu Arg Arg Leu Val Thr Leu Ile Ser Gln 
            180                 185                 190         


Gln Ala Thr Leu Leu Ala Ser Asn Glu Ala Phe Lys Lys Gln Ala Glu 
        195                 200                 205             


Ser Ala Ser Glu Ala Ala Lys Lys Tyr Met Glu Glu Asn Asp Gln Leu 
    210                 215                 220                 


Lys Lys Gly Ala Ala Val Asp Gly Gly Lys Leu Asp Val Gly Asn Ala 
225                 230                 235                 240 


Glu Val Lys Leu Glu Glu Glu Asn Arg Ser Leu Lys Ala Asp Leu Gln 
                245                 250                 255     


Lys Leu Lys Asp Glu Leu Ala Ser Thr Lys Gln Lys Leu Glu Lys Ala 
            260                 265                 270         


Glu Asn Gln Val Leu Ala Met Arg Lys Gln Ser Glu Gly Leu Thr Lys 
        275                 280                 285             


Glu Tyr Asp Arg Leu Leu Glu Glu His Ala Lys Leu Gln Ala Ala Val 
    290                 295                 300                 


Asp Gly Pro Met Asp Lys Lys Glu Glu 
305                 310             


<210>  1443
<211>  565
<212>  PRT
<213>  Homo sapiens

<400>  1443

Met Glu Asp Ser Asp Ser Ala Ala Lys Gln Leu Gly Leu Ala Glu Ala 
1               5                   10                  15      


Ala Ala Val Ala Ala Ala Ala Ala Val Ala Ala Ala Ala Ala Ala Ala 
            20                  25                  30          


Ala Gly Gly Glu Ala Glu Glu Pro Val Leu Ser Arg Asp Glu Asp Ser 
        35                  40                  45              


Glu Glu Asp Ala Asp Ser Glu Ala Glu Arg Glu Thr Pro Arg Val Thr 
    50                  55                  60                  


Ala Val Ala Val Met Ala Ala Glu Pro Gly His Met Asp Met Gly Ala 
65                  70                  75                  80  


Glu Ala Leu Pro Gly Pro Asp Glu Ala Ala Ala Ala Ala Ala Phe Ala 
                85                  90                  95      


Glu Val Thr Thr Val Thr Val Ala Asn Val Gly Ala Ala Ala Asp Asn 
            100                 105                 110         


Val Phe Thr Thr Ser Val Ala Asn Ala Ala Ser Ile Ser Gly His Val 
        115                 120                 125             


Leu Ser Gly Arg Thr Ala Leu Gln Ile Gly Asp Ser Leu Asn Thr Glu 
    130                 135                 140                 


Lys Ala Thr Leu Ile Val Val His Thr Asp Gly Ser Ile Val Glu Thr 
145                 150                 155                 160 


Thr Gly Leu Lys Gly Pro Ala Ala Pro Leu Thr Pro Gly Pro Gln Ser 
                165                 170                 175     


Pro Pro Thr Pro Leu Ala Pro Gly Gln Glu Lys Gly Gly Thr Lys Tyr 
            180                 185                 190         


Asn Trp Asp Pro Ser Val Tyr Asp Ser Glu Leu Pro Val Arg Cys Arg 
        195                 200                 205             


Asn Ile Ser Gly Thr Leu Tyr Lys Asn Arg Leu Gly Ser Gly Gly Arg 
    210                 215                 220                 


Gly Arg Cys Ile Lys Gln Gly Glu Asn Trp Tyr Ser Pro Thr Glu Phe 
225                 230                 235                 240 


Glu Ala Met Ala Gly Arg Ala Ser Ser Lys Asp Trp Lys Arg Ser Ile 
                245                 250                 255     


Arg Tyr Ala Gly Arg Pro Leu Gln Cys Leu Ile Gln Asp Gly Ile Leu 
            260                 265                 270         


Asn Pro His Ala Ala Ser Cys Thr Cys Ala Ala Cys Cys Asp Asp Met 
        275                 280                 285             


Thr Leu Ser Gly Pro Val Arg Leu Phe Val Pro Tyr Lys Arg Arg Lys 
    290                 295                 300                 


Lys Glu Asn Glu Leu Pro Thr Thr Pro Val Lys Lys Asp Ser Pro Lys 
305                 310                 315                 320 


Asn Ile Thr Leu Leu Pro Ala Thr Ala Ala Thr Thr Phe Thr Val Thr 
                325                 330                 335     


Pro Ser Gly Gln Ile Thr Thr Ser Gly Ala Leu Thr Phe Asp Arg Ala 
            340                 345                 350         


Ser Thr Val Glu Ala Thr Ala Val Ile Ser Glu Ser Pro Ala Gln Gly 
        355                 360                 365             


Asp Val Phe Ala Gly Ala Thr Val Gln Glu Ala Ser Val Gln Pro Pro 
    370                 375                 380                 


Cys Arg Ala Ser His Pro Glu Pro His Tyr Pro Gly Tyr Gln Asp Ser 
385                 390                 395                 400 


Cys Gln Ile Ala Pro Phe Pro Glu Ala Ala Leu Pro Thr Ser His Pro 
                405                 410                 415     


Lys Ile Val Leu Thr Ser Leu Pro Ala Leu Ala Val Pro Pro Pro Thr 
            420                 425                 430         


Pro Thr Lys Ala Ala Pro Pro Ala Leu Val Asn Gly Leu Glu Leu Ser 
        435                 440                 445             


Glu Pro Arg Ser Trp Leu Tyr Leu Glu Glu Met Val Asn Ser Leu Leu 
    450                 455                 460                 


Asn Thr Ala Gln Gln Leu Lys Thr Leu Phe Glu Gln Ala Lys His Ala 
465                 470                 475                 480 


Ser Thr Tyr Arg Glu Ala Ala Thr Asn Gln Ala Lys Ile His Ala Asp 
                485                 490                 495     


Ala Glu Arg Lys Glu Gln Ser Cys Val Asn Cys Gly Arg Glu Ala Met 
            500                 505                 510         


Ser Glu Cys Thr Gly Cys His Lys Val Asn Tyr Cys Ser Thr Phe Cys 
        515                 520                 525             


Gln Arg Lys Asp Trp Lys Asp His Gln His Ile Cys Gly Gln Ser Ala 
    530                 535                 540                 


Ala Val Thr Val Gln Ala Asp Glu Val His Val Ala Glu Ser Val Met 
545                 550                 555                 560 


Glu Lys Val Thr Val 
                565 


<210>  1444
<211>  203
<212>  PRT
<213>  Homo sapiens

<400>  1444

Met Gly Gly Ser Leu Arg Val Ala Val Leu Gly Ala Pro Gly Val Gly 
1               5                   10                  15      


Lys Thr Ala Ile Ile Arg Gln Phe Leu Phe Gly Asp Tyr Pro Glu Arg 
            20                  25                  30          


His Arg Pro Thr Asp Gly Pro Arg Leu Tyr Arg Pro Ala Val Leu Leu 
        35                  40                  45              


Asp Gly Ala Val Tyr Asp Leu Ser Ile Arg Asp Gly Asp Val Ala Gly 
    50                  55                  60                  


Pro Gly Ser Ser Pro Gly Gly Pro Glu Glu Trp Pro Asp Ala Lys Asp 
65                  70                  75                  80  


Trp Ser Leu Gln Asp Thr Asp Ala Phe Val Leu Val Tyr Asp Ile Cys 
                85                  90                  95      


Ser Pro Asp Ser Phe Asp Tyr Val Lys Ala Leu Arg Gln Arg Ile Ala 
            100                 105                 110         


Glu Thr Arg Pro Ala Gly Ala Pro Glu Ala Pro Ile Leu Val Val Gly 
        115                 120                 125             


Asn Lys Arg Asp Arg Gln Arg Leu Arg Phe Gly Pro Arg Arg Ala Leu 
    130                 135                 140                 


Ala Ala Leu Val Arg Arg Gly Trp Arg Cys Gly Tyr Leu Glu Cys Ser 
145                 150                 155                 160 


Ala Lys Tyr Asn Trp His Val Leu Arg Leu Phe Arg Glu Leu Leu Arg 
                165                 170                 175     


Cys Ala Leu Val Arg Ala Arg Pro Ala His Pro Ala Leu Arg Leu Gln 
            180                 185                 190         


Gly Ala Leu His Pro Ala Arg Cys Ser Leu Met 
        195                 200             


<210>  1445
<211>  1069
<212>  PRT
<213>  Homo sapiens

<400>  1445

Met Val Val Pro Glu Lys Glu Gln Ser Trp Ile Pro Lys Ile Phe Lys 
1               5                   10                  15      


Lys Lys Thr Cys Thr Thr Phe Ile Val Asp Ser Thr Asp Pro Gly Gly 
            20                  25                  30          


Thr Leu Cys Gln Cys Gly Arg Pro Arg Thr Ala His Pro Ala Val Ala 
        35                  40                  45              


Met Glu Asp Ala Phe Gly Ala Ala Val Val Thr Val Trp Asp Ser Asp 
    50                  55                  60                  


Ala His Thr Thr Glu Lys Pro Thr Asp Ala Tyr Gly Glu Leu Asp Phe 
65                  70                  75                  80  


Thr Gly Ala Gly Arg Lys His Ser Asn Phe Leu Arg Leu Ser Asp Arg 
                85                  90                  95      


Thr Asp Pro Ala Ala Val Tyr Ser Leu Val Thr Arg Thr Trp Gly Phe 
            100                 105                 110         


Arg Ala Pro Asn Leu Val Val Ser Val Leu Gly Gly Ser Gly Gly Pro 
        115                 120                 125             


Val Leu Gln Thr Trp Leu Gln Asp Leu Leu Arg Arg Gly Leu Val Arg 
    130                 135                 140                 


Ala Ala Gln Ser Thr Gly Ala Trp Ile Val Thr Gly Gly Leu His Thr 
145                 150                 155                 160 


Gly Ile Gly Arg His Val Gly Val Ala Val Arg Asp His Gln Met Ala 
                165                 170                 175     


Ser Thr Gly Gly Thr Lys Val Val Ala Met Gly Val Ala Pro Trp Gly 
            180                 185                 190         


Val Val Arg Asn Arg Asp Thr Leu Ile Asn Pro Lys Gly Ser Phe Pro 
        195                 200                 205             


Ala Arg Tyr Arg Trp Arg Gly Asp Pro Glu Asp Gly Val Gln Phe Pro 
    210                 215                 220                 


Leu Asp Tyr Asn Tyr Ser Ala Phe Phe Leu Val Asp Asp Gly Thr His 
225                 230                 235                 240 


Gly Cys Leu Gly Gly Glu Asn Arg Phe Arg Leu Arg Leu Glu Ser Tyr 
                245                 250                 255     


Ile Ser Gln Gln Lys Thr Gly Val Gly Gly Thr Gly Ile Asp Ile Pro 
            260                 265                 270         


Val Leu Leu Leu Leu Ile Asp Gly Asp Glu Lys Met Leu Thr Arg Ile 
        275                 280                 285             


Glu Asn Ala Thr Gln Ala Gln Leu Pro Cys Leu Leu Val Ala Gly Ser 
    290                 295                 300                 


Gly Gly Ala Ala Asp Cys Leu Ala Glu Thr Leu Glu Asp Thr Leu Ala 
305                 310                 315                 320 


Pro Gly Ser Gly Gly Ala Arg Gln Gly Glu Ala Arg Asp Arg Ile Arg 
                325                 330                 335     


Arg Phe Phe Pro Lys Gly Asp Leu Glu Val Leu Gln Ala Gln Val Glu 
            340                 345                 350         


Arg Ile Met Thr Arg Lys Glu Leu Leu Thr Val Tyr Ser Ser Glu Asp 
        355                 360                 365             


Gly Ser Glu Glu Phe Glu Thr Ile Val Leu Lys Ala Leu Val Lys Ala 
    370                 375                 380                 


Cys Gly Ser Ser Glu Ala Ser Ala Tyr Leu Asp Glu Leu Arg Leu Ala 
385                 390                 395                 400 


Val Ala Trp Asn Arg Val Asp Ile Ala Gln Ser Glu Leu Phe Arg Gly 
                405                 410                 415     


Asp Ile Gln Trp Arg Ser Phe His Leu Glu Ala Ser Leu Met Asp Ala 
            420                 425                 430         


Leu Leu Asn Asp Arg Pro Glu Phe Val Arg Leu Leu Ile Ser His Gly 
        435                 440                 445             


Leu Ser Leu Gly His Phe Leu Thr Pro Met Arg Leu Ala Gln Leu Tyr 
    450                 455                 460                 


Ser Ala Ala Pro Ser Asn Ser Leu Ile Arg Asn Leu Leu Asp Gln Ala 
465                 470                 475                 480 


Ser His Ser Ala Gly Thr Lys Ala Pro Ala Leu Lys Gly Gly Ala Ala 
                485                 490                 495     


Glu Leu Arg Pro Pro Asp Val Gly His Val Leu Arg Met Leu Leu Gly 
            500                 505                 510         


Lys Met Cys Ala Pro Arg Tyr Pro Ser Gly Gly Ala Trp Asp Pro His 
        515                 520                 525             


Pro Gly Gln Gly Phe Gly Glu Ser Met Tyr Leu Leu Ser Asp Lys Ala 
    530                 535                 540                 


Thr Ser Pro Leu Ser Leu Asp Ala Gly Leu Gly Gln Ala Pro Trp Ser 
545                 550                 555                 560 


Asp Leu Leu Leu Trp Ala Leu Leu Leu Asn Arg Ala Gln Met Ala Met 
                565                 570                 575     


Tyr Phe Trp Glu Met Gly Ser Asn Ala Val Ser Ser Ala Leu Gly Ala 
            580                 585                 590         


Cys Leu Leu Leu Arg Val Met Ala Arg Leu Glu Pro Asp Ala Glu Glu 
        595                 600                 605             


Ala Ala Arg Arg Lys Asp Leu Ala Phe Lys Phe Glu Gly Met Gly Val 
    610                 615                 620                 


Asp Leu Phe Gly Glu Cys Tyr Arg Ser Ser Glu Val Arg Ala Ala Arg 
625                 630                 635                 640 


Leu Leu Leu Arg Arg Cys Pro Leu Trp Gly Asp Ala Thr Cys Leu Gln 
                645                 650                 655     


Leu Ala Met Gln Ala Asp Ala Arg Ala Phe Phe Ala Gln Asp Gly Val 
            660                 665                 670         


Gln Ser Leu Leu Thr Gln Lys Trp Trp Gly Asp Met Ala Ser Thr Thr 
        675                 680                 685             


Pro Ile Trp Ala Leu Val Leu Ala Phe Phe Cys Pro Pro Leu Ile Tyr 
    690                 695                 700                 


Thr Arg Leu Ile Thr Phe Arg Lys Ser Glu Glu Glu Pro Thr Arg Glu 
705                 710                 715                 720 


Glu Leu Glu Phe Asp Met Asp Ser Val Ile Asn Gly Glu Gly Pro Val 
                725                 730                 735     


Gly Leu Thr Pro Gly Leu Tyr His Leu Gly Arg Thr Val Leu Cys Ile 
            740                 745                 750         


Asp Phe Met Val Phe Thr Val Arg Leu Leu His Ile Phe Thr Val Asn 
        755                 760                 765             


Lys Gln Leu Gly Pro Lys Ile Val Ile Val Ser Lys Met Met Lys Asp 
    770                 775                 780                 


Val Phe Phe Phe Leu Phe Phe Leu Gly Val Trp Leu Val Ala Tyr Gly 
785                 790                 795                 800 


Val Ala Thr Glu Gly Leu Leu Arg Pro Arg Asp Ser Asp Phe Pro Ser 
                805                 810                 815     


Ile Leu Arg Arg Val Phe Tyr Arg Pro Tyr Leu Gln Ile Phe Gly Gln 
            820                 825                 830         


Ile Pro Gln Glu Asp Met Asp Val Ala Leu Met Glu His Ser Asn Cys 
        835                 840                 845             


Ser Ser Glu Pro Gly Phe Trp Ala His Pro Pro Gly Ala Gln Ala Gly 
    850                 855                 860                 


Thr Cys Val Ser Gln Tyr Ala Asn Trp Leu Val Val Leu Leu Leu Val 
865                 870                 875                 880 


Ile Phe Leu Leu Val Ala Asn Ile Leu Leu Val Asn Leu Leu Ile Ala 
                885                 890                 895     


Met Phe Ser Tyr Thr Phe Gly Lys Val Gln Gly Asn Ser Asp Leu Tyr 
            900                 905                 910         


Trp Lys Ala Gln Arg Tyr Arg Leu Ile Arg Glu Phe His Ser Arg Pro 
        915                 920                 925             


Ala Leu Ala Pro Pro Phe Ile Val Ile Ser His Leu Arg Leu Leu Leu 
    930                 935                 940                 


Arg Gln Leu Cys Arg Arg Pro Arg Ser Pro Gln Pro Ser Ser Pro Ala 
945                 950                 955                 960 


Leu Glu His Phe Arg Val Tyr Leu Ser Lys Glu Ala Glu Arg Lys Leu 
                965                 970                 975     


Leu Thr Trp Glu Ser Val His Lys Glu Asn Phe Leu Leu Ala Arg Ala 
            980                 985                 990         


Arg Asp Lys Arg Glu Ser Asp Ser  Glu Arg Leu Lys Arg  Thr Ser Gln 
        995                 1000                 1005             


Lys Val  Asp Leu Ala Leu Lys  Gln Leu Gly His Ile  Arg Glu Tyr 
    1010                 1015                 1020             


Glu Gln  Arg Leu Lys Val Leu  Glu Arg Glu Val Gln  Gln Cys Ser 
    1025                 1030                 1035             


Arg Val  Leu Gly Trp Val Ala  Glu Ala Leu Ser Arg  Ser Ala Leu 
    1040                 1045                 1050             


Leu Pro  Pro Gly Gly Pro Pro  Pro Pro Asp Leu Pro  Gly Ser Lys 
    1055                 1060                 1065             


Asp 
    


<210>  1446
<211>  199
<212>  PRT
<213>  Homo sapiens

<400>  1446

Met Glu Asn Phe Arg Lys Val Arg Ser Glu Glu Ala Pro Ala Gly Cys 
1               5                   10                  15      


Gly Ala Glu Gly Gly Gly Pro Gly Ser Gly Pro Phe Ala Asp Leu Ala 
            20                  25                  30          


Pro Gly Ala Val His Met Arg Val Lys Glu Gly Ser Lys Ile Arg Asn 
        35                  40                  45              


Leu Met Ala Phe Ala Thr Ala Ser Met Ala Gln Pro Ala Thr Arg Ala 
    50                  55                  60                  


Ile Val Phe Ser Gly Cys Gly Arg Ala Thr Thr Lys Thr Val Thr Cys 
65                  70                  75                  80  


Ala Glu Ile Leu Lys Arg Arg Leu Ala Gly Leu His Gln Val Thr Arg 
                85                  90                  95      


Leu Arg Tyr Arg Ser Val Arg Glu Val Trp Gln Ser Leu Pro Pro Gly 
            100                 105                 110         


Pro Thr Gln Gly Gln Thr Pro Gly Glu Pro Ala Ala Ser Leu Ser Val 
        115                 120                 125             


Leu Lys Asn Val Pro Gly Leu Ala Ile Leu Leu Ser Lys Asp Ala Leu 
    130                 135                 140                 


Asp Pro Arg Gln Pro Gly Tyr Gln Pro Pro Asn Pro His Pro Gly Pro 
145                 150                 155                 160 


Ser Ser Pro Pro Ala Ala Pro Ala Ser Lys Arg Ser Leu Gly Glu Pro 
                165                 170                 175     


Ala Ala Gly Glu Gly Ser Ala Lys Arg Ser Gln Pro Glu Pro Gly Val 
            180                 185                 190         


Ala Asp Glu Asp Gln Thr Ala 
        195                 


<210>  1447
<211>  228
<212>  PRT
<213>  Homo sapiens

<400>  1447

Met Ser Tyr Ala Glu Lys Pro Asp Glu Ile Thr Lys Asp Glu Trp Met 
1               5                   10                  15      


Glu Lys Leu Asn Asn Leu His Val Gln Arg Ala Asp Met Asn Arg Leu 
            20                  25                  30          


Ile Met Asn Tyr Leu Val Thr Glu Gly Phe Lys Glu Ala Ala Glu Lys 
        35                  40                  45              


Phe Arg Met Glu Ser Gly Ile Glu Pro Ser Val Asp Leu Glu Thr Leu 
    50                  55                  60                  


Asp Glu Arg Ile Lys Ile Arg Glu Met Ile Leu Lys Gly Gln Ile Gln 
65                  70                  75                  80  


Glu Ala Ile Ala Leu Ile Asn Ser Leu His Pro Glu Leu Leu Asp Thr 
                85                  90                  95      


Asn Arg Tyr Leu Tyr Phe His Leu Gln Gln Gln His Leu Ile Glu Leu 
            100                 105                 110         


Ile Arg Gln Arg Glu Thr Glu Ala Ala Leu Glu Phe Ala Gln Thr Gln 
        115                 120                 125             


Leu Ala Glu Gln Gly Glu Glu Ser Arg Glu Cys Leu Thr Glu Met Glu 
    130                 135                 140                 


Arg Thr Leu Ala Leu Leu Ala Phe Asp Ser Pro Glu Glu Ser Pro Phe 
145                 150                 155                 160 


Gly Asp Leu Leu His Thr Met Gln Arg Gln Lys Val Trp Ser Glu Val 
                165                 170                 175     


Asn Gln Ala Val Leu Asp Tyr Glu Asn Arg Glu Ser Thr Pro Lys Leu 
            180                 185                 190         


Ala Lys Leu Leu Lys Leu Leu Leu Trp Ala Gln Asn Glu Leu Asp Gln 
        195                 200                 205             


Lys Lys Val Lys Tyr Pro Lys Met Thr Asp Leu Ser Lys Gly Val Ile 
    210                 215                 220                 


Glu Glu Pro Lys 
225             


<210>  1448
<211>  1132
<212>  PRT
<213>  Homo sapiens

<400>  1448

Met Gly Ala Asn Ala Ser Asn Tyr Pro His Ser Cys Ser Pro Arg Val 
1               5                   10                  15      


Gly Gly Asn Ser Gln Ala Gln Gln Thr Phe Ile Gly Thr Ser Ser Tyr 
            20                  25                  30          


Ser Gln Gln Gly Tyr Gly Cys Glu Ser Lys Leu Tyr Ser Leu Asp His 
        35                  40                  45              


Gly His Glu Lys Pro Gln Asp Lys Lys Lys Arg Thr Ser Gly Leu Ala 
    50                  55                  60                  


Thr Leu Lys Lys Lys Phe Ile Lys Arg Arg Lys Ser Asn Arg Ser Ala 
65                  70                  75                  80  


Asp His Ala Lys Gln Met Arg Glu Leu Leu Ser Gly Trp Asp Val Arg 
                85                  90                  95      


Asp Val Asn Ala Leu Val Glu Glu Tyr Glu Gly Thr Ser Ala Leu Lys 
            100                 105                 110         


Glu Leu Ser Leu Gln Ala Ser Leu Ala Arg Pro Glu Ala Arg Thr Leu 
        115                 120                 125             


Gln Lys Asp Met Ala Asp Leu Tyr Glu Tyr Lys Tyr Cys Thr Asp Val 
    130                 135                 140                 


Asp Leu Ile Phe Gln Glu Thr Cys Phe Pro Val His Arg Ala Ile Leu 
145                 150                 155                 160 


Ala Ala Arg Cys Pro Phe Phe Lys Thr Leu Leu Ser Ser Ser Pro Glu 
                165                 170                 175     


Tyr Gly Ala Glu Ile Ile Met Asp Ile Asn Thr Ala Gly Ile Asp Met 
            180                 185                 190         


Pro Met Phe Ser Ala Leu Leu His Tyr Leu Tyr Thr Gly Glu Phe Gly 
        195                 200                 205             


Met Glu Asp Ser Arg Phe Gln Asn Val Asp Ile Leu Val Gln Leu Ser 
    210                 215                 220                 


Glu Glu Phe Gly Thr Pro Asn Ser Leu Asp Val Asp Met Arg Gly Leu 
225                 230                 235                 240 


Phe Asp Tyr Met Cys Tyr Tyr Asp Val Val Leu Ser Phe Ser Ser Asp 
                245                 250                 255     


Ser Glu Leu Val Glu Ala Phe Gly Gly Asn Gln Asn Cys Leu Asp Glu 
            260                 265                 270         


Glu Leu Lys Ala His Lys Ala Val Ile Ser Ala Arg Ser Pro Phe Phe 
        275                 280                 285             


Arg Asn Leu Leu Gln Arg Arg Ile Arg Thr Gly Glu Glu Ile Thr Asp 
    290                 295                 300                 


Arg Thr Leu Arg Thr Pro Thr Arg Ile Ile Leu Asp Glu Ser Ile Ile 
305                 310                 315                 320 


Pro Lys Lys Tyr Ala Thr Val Ile Leu His Cys Met Tyr Thr Asp Val 
                325                 330                 335     


Val Asp Leu Ser Val Leu His Cys Ser Pro Ser Val Gly Ser Leu Ser 
            340                 345                 350         


Glu Val Gln Ala Leu Val Ala Gly Lys Pro Asn Met Thr Arg Ala Glu 
        355                 360                 365             


Glu Ala Met Glu Leu Tyr His Ile Ala Leu Phe Leu Glu Phe Asn Met 
    370                 375                 380                 


Leu Ala Gln Gly Cys Glu Asp Ile Ile Ala Glu Ser Ile Ser Leu Asp 
385                 390                 395                 400 


Thr Leu Ile Ala Ile Leu Lys Trp Ser Ser His Pro Tyr Gly Ser Lys 
                405                 410                 415     


Trp Val His Arg Gln Ala Leu His Phe Leu Cys Glu Glu Phe Ser Gln 
            420                 425                 430         


Val Met Thr Ser Asp Val Phe Tyr Glu Leu Ser Lys Asp His Leu Leu 
        435                 440                 445             


Thr Ala Ile Gln Ser Asp Tyr Leu Gln Ala Ser Glu Gln Asp Ile Leu 
    450                 455                 460                 


Lys Tyr Leu Ile Lys Trp Gly Glu His Gln Leu Met Lys Arg Ile Ala 
465                 470                 475                 480 


Asp Arg Glu Pro Asn Leu Leu Ser Gly Thr Ala His Ser Val Asn Lys 
                485                 490                 495     


Arg Gly Val Lys Arg Arg Asp Leu Asp Met Glu Glu Leu Arg Glu Ile 
            500                 505                 510         


Leu Ser Ser Leu Leu Pro Phe Val Arg Ile Glu His Ile Leu Pro Ile 
        515                 520                 525             


Asn Ser Glu Val Leu Ser Asp Ala Met Lys Arg Gly Leu Ile Ser Thr 
    530                 535                 540                 


Pro Pro Ser Asp Met Leu Pro Thr Thr Glu Gly Gly Lys Ser Asn Ala 
545                 550                 555                 560 


Trp Leu Arg Gln Lys Asn Ala Gly Ile Tyr Val Arg Pro Arg Leu Phe 
                565                 570                 575     


Ser Pro Tyr Val Glu Glu Ala Lys Ser Val Leu Asp Glu Met Met Val 
            580                 585                 590         


Glu Gln Thr Asp Leu Val Arg Leu Arg Met Val Arg Met Ser Asn Val 
        595                 600                 605             


Pro Asp Thr Leu Tyr Met Val Asn Asn Ala Val Pro Gln Cys Cys His 
    610                 615                 620                 


Met Ile Ser His Gln Gln Ile Ser Ser Asn Gln Ser Ser Pro Pro Ser 
625                 630                 635                 640 


Val Val Ala Asn Glu Ile Pro Val Pro Arg Leu Leu Ile Met Lys Asp 
                645                 650                 655     


Met Val Arg Arg Leu Gln Glu Leu Arg His Thr Glu Gln Val Gln Arg 
            660                 665                 670         


Ala Tyr Ala Leu Asn Cys Gly Glu Gly Ala Thr Val Ser Tyr Glu Ile 
        675                 680                 685             


Gln Ile Arg Val Leu Arg Glu Phe Gly Leu Ala Asp Ala Ala Ala Glu 
    690                 695                 700                 


Leu Leu Gln Asn Pro His Lys Phe Phe Pro Asp Glu Arg Phe Gly Asp 
705                 710                 715                 720 


Glu Ser Pro Leu Leu Thr Met Arg Gln Pro Gly Arg Cys Arg Val Asn 
                725                 730                 735     


Ser Thr Pro Pro Ala Glu Thr Met Phe Thr Asp Leu Asp Ser Phe Val 
            740                 745                 750         


Ala Phe His Pro Pro Leu Pro Pro Pro Pro Pro Pro Tyr His Pro Pro 
        755                 760                 765             


Ala Thr Pro Ile His Asn Gln Leu Lys Ala Gly Trp Lys Gln Arg Pro 
    770                 775                 780                 


Pro Ser Gln His Pro Ser Arg Ser Phe Ser Tyr Pro Cys Asn His Ser 
785                 790                 795                 800 


Leu Phe His Ser Arg Thr Ala Pro Lys Ala Gly Pro Pro Pro Val Tyr 
                805                 810                 815     


Leu Pro Ser Val Lys Ala Ala Pro Pro Asp Cys Thr Ser Thr Ala Gly 
            820                 825                 830         


Leu Gly Arg Gln Thr Val Ala Ala Ala Ala Ala Thr Thr Thr Ser Thr 
        835                 840                 845             


Ala Thr Ala Ala Ala Ala Ala Ala Ser Glu Lys Gln Val Arg Thr Gln 
    850                 855                 860                 


Pro Val Leu Asn Asp Leu Met Pro Asp Ile Ala Val Gly Val Ser Thr 
865                 870                 875                 880 


Leu Ser Leu Lys Asp Arg Arg Leu Pro Glu Leu Ala Val Asp Thr Glu 
                885                 890                 895     


Leu Ser Gln Ser Val Ser Glu Ala Gly Pro Gly Pro Pro Gln His Leu 
            900                 905                 910         


Ser Cys Ile Pro Gln Arg His Thr His Thr Ser Arg Lys Lys His Thr 
        915                 920                 925             


Leu Glu Gln Lys Thr Asp Thr Arg Glu Asn Pro Gln Glu Tyr Pro Asp 
    930                 935                 940                 


Phe Tyr Asp Phe Ser Asn Ala Ala Cys Arg Pro Ser Thr Pro Ala Leu 
945                 950                 955                 960 


Ser Arg Arg Thr Pro Ser Pro Ser Gln Gly Gly Tyr Phe Gly Pro Asp 
                965                 970                 975     


Leu Tyr Ser His Asn Lys Ala Ser Pro Ser Gly Leu Lys Ser Ala Tyr 
            980                 985                 990         


Leu Pro Gly Gln Thr Ser Pro Lys  Lys Gln Glu Glu Ala  Arg Arg Glu 
        995                 1000                 1005             


Tyr Pro  Leu Ser Pro Asp Gly  His Leu His Arg Gln  Lys Asn Glu 
    1010                 1015                 1020             


Pro Ile  His Leu Asp Val Val  Glu Gln Pro Pro Gln  Arg Ser Asp 
    1025                 1030                 1035             


Phe Pro  Leu Ala Ala Pro Glu  Asn Ala Ser Thr Gly  Pro Ala His 
    1040                 1045                 1050             


Val Arg  Gly Arg Thr Ala Val  Glu Thr Asp Leu Thr  Phe Gly Leu 
    1055                 1060                 1065             


Thr Pro  Asn Arg Pro Ser Leu  Ser Ala Cys Ser Ser  Glu Ala Pro 
    1070                 1075                 1080             


Glu Glu  Arg Ser Gly Arg Arg  Leu Ala Asp Ser Glu  Ser Leu Gly 
    1085                 1090                 1095             


His Gly  Ala Gln Arg Asn Thr  Asp Leu Glu Arg Glu  Asp Ser Ile 
    1100                 1105                 1110             


Ser Arg  Gly Arg Arg Ser Pro  Ser Lys Pro Asp Phe  Leu Tyr Lys 
    1115                 1120                 1125             


Lys Ser  Ala Leu 
    1130         


<210>  1449
<211>  200
<212>  PRT
<213>  Homo sapiens

<400>  1449

Met Asp Asp Lys Lys Lys Lys Arg Ser Pro Lys Pro Cys Leu Ala Gln 
1               5                   10                  15      


Pro Ala Gln Ala Pro Gly Thr Leu Arg Arg Val Pro Val Pro Thr Ser 
            20                  25                  30          


His Ser Gly Ser Leu Ala Leu Gly Leu Pro His Leu Pro Ser Pro Lys 
        35                  40                  45              


Gln Arg Ala Lys Phe Lys Arg Val Gly Lys Glu Lys Cys Arg Pro Val 
    50                  55                  60                  


Leu Ala Gly Gly Gly Ser Gly Ser Ala Gly Thr Pro Leu Gln His Ser 
65                  70                  75                  80  


Phe Leu Thr Glu Val Thr Asp Val Tyr Glu Met Glu Gly Gly Leu Leu 
                85                  90                  95      


Asn Leu Leu Asn Asp Phe His Ser Gly Arg Leu Gln Ala Phe Gly Lys 
            100                 105                 110         


Glu Cys Ser Phe Glu Gln Leu Glu His Val Arg Glu Met Gln Glu Lys 
        115                 120                 125             


Leu Ala Arg Leu His Phe Ser Leu Asp Val Cys Gly Glu Glu Glu Asp 
    130                 135                 140                 


Asp Glu Glu Glu Glu Asp Gly Val Thr Glu Gly Leu Pro Glu Glu Gln 
145                 150                 155                 160 


Lys Lys Thr Met Ala Asp Arg Asn Leu Asp Gln Leu Leu Ser Asn Leu 
                165                 170                 175     


Glu Asp Leu Ser Asn Ser Ile Gln Lys Leu His Leu Ala Glu Asn Ala 
            180                 185                 190         


Glu Pro Glu Glu Gln Ser Ala Ala 
        195                 200 


<210>  1450
<211>  1094
<212>  PRT
<213>  Homo sapiens

<400>  1450

Met Ala Ala Arg Gln Ala Val Gly Ser Gly Ala Gln Glu Thr Cys Gly 
1               5                   10                  15      


Leu Asp Arg Ile Leu Glu Ala Leu Lys Leu Leu Leu Ser Pro Gly Gly 
            20                  25                  30          


Ser Gly Ser Ser Ser Leu Gln Val Thr Lys His Asp Val Leu Leu Ala 
        35                  40                  45              


Thr Leu Lys Ser Asn Leu Ser Ala Leu Glu Asp Lys Phe Leu Lys Asp 
    50                  55                  60                  


Pro Gln Trp Lys Asn Leu Lys Leu Leu Arg Asp Glu Ile Ala Asp Lys 
65                  70                  75                  80  


Ala Glu Trp Pro Gln Asn Ser Val Asp Val Thr Trp Ser Phe Thr Ser 
                85                  90                  95      


Gln Thr Leu Leu Leu Leu Leu Cys Leu Lys Glu Thr Met Ile Arg Leu 
            100                 105                 110         


Ala Ala Asn Phe Asn Pro Gly Lys Pro Asn Pro Arg Thr Pro Glu Val 
        115                 120                 125             


Ala Pro Ala Leu Ser Pro Asp Ala Leu Ser Ile Ser Gln Gln Lys Thr 
    130                 135                 140                 


Val Gln Phe Val Leu Gln Phe Val Val Thr Leu Gly Ile Cys Pro Tyr 
145                 150                 155                 160 


Leu Met Pro Gly Val Gly Val Pro Leu Arg Tyr Arg Thr Glu Phe Gly 
                165                 170                 175     


Ala Val Val Gln Asp Val Val Cys Phe Asp Ala Ala Pro Asp Ala Thr 
            180                 185                 190         


Arg Arg Leu Tyr Thr Ser Cys Lys Ala Leu Leu Asn Val Ala Gln His 
        195                 200                 205             


Thr Ser Leu Gly Ser Leu Ile Phe Cys His His Phe Gly Asp Ile Ala 
    210                 215                 220                 


Ala Gly Leu Cys Gln Leu Gly Phe Cys Pro Thr Lys Arg Lys Leu Leu 
225                 230                 235                 240 


Thr Pro Ala Glu Glu Val Leu Thr Glu Glu Glu Arg Thr Leu Ser Arg 
                245                 250                 255     


Gly Ala Leu Arg Asp Met Leu Asp Gln Val Tyr Gln Pro Leu Ala Val 
            260                 265                 270         


Arg Glu Leu Leu Ile Leu Gln Gly Gly Pro Pro Gln Ser Cys Thr Asp 
        275                 280                 285             


Val Lys Thr Gln Met Arg Cys Arg Ala Pro Ala Trp Leu Arg Arg Leu 
    290                 295                 300                 


Cys Gly Gln Leu Leu Ser Glu Arg Leu Met Arg Pro Asn Gly Val Gln 
305                 310                 315                 320 


Ala Val Val Arg Gly Ile Leu Glu Gly Ala Gly Ala Gly Ala Ala Gly 
                325                 330                 335     


Gly Ser Asp Ala Glu Val Thr Ala Ala Asp Trp Lys Lys Cys Asp Leu 
            340                 345                 350         


Ile Ala Lys Ile Leu Ala Ser Cys Pro Gln Gln Ser Leu Ser Pro Glu 
        355                 360                 365             


Asn Tyr Tyr Arg Asp Ile Cys Pro Gln Val Leu Asp Leu Phe His Phe 
    370                 375                 380                 


Gln Asp Lys Leu Thr Ala Arg Gln Phe Gln Arg Val Ala Thr Thr Thr 
385                 390                 395                 400 


Phe Ile Thr Leu Ser Arg Glu Arg Pro His Leu Ala Ala Lys Tyr Leu 
                405                 410                 415     


Leu Gln Pro Val Leu Ala Pro Leu His Arg Cys Leu Asn Thr Ala Glu 
            420                 425                 430         


Leu Ser Glu Ser Asp Met Val Pro Gly Thr Ile Leu Val Thr Glu Glu 
        435                 440                 445             


Glu Leu Ser Arg Cys Ile Glu Asp Val Phe Lys Val Tyr Val Val Gly 
    450                 455                 460                 


Asn Glu Pro Leu Thr Val Leu Met Asp Ser Leu Leu Pro Val Leu Gly 
465                 470                 475                 480 


Val Leu Phe Leu Leu Tyr Cys Phe Thr Lys Gln Ser Val Ser His Ile 
                485                 490                 495     


Arg Ser Leu Cys Gln Glu Ile Leu Leu Trp Ile Leu Gly Lys Leu Glu 
            500                 505                 510         


Arg Lys Lys Ala Ile Ala Ser Leu Lys Gly Phe Ala Gly Leu Asp Lys 
        515                 520                 525             


Ala Val Pro Ser Leu His Ser Leu Cys Gln Phe Arg Val Ala Thr Gln 
    530                 535                 540                 


Gly Gly Ile Met Ile Thr Ile Lys Glu Ala Ile Ser Asp Glu Asp Glu 
545                 550                 555                 560 


Asp Glu Ala Leu Tyr Gln Lys Val Ser Ser Glu Gln Gly Arg Val Glu 
                565                 570                 575     


His Leu Gly Asp Leu Leu Ser His Cys Gln Glu Cys Gly Leu Ala Gly 
            580                 585                 590         


Asp Phe Phe Ile Phe Cys Leu Lys Glu Leu Thr His Val Ala Ser Glu 
        595                 600                 605             


Asn Glu Thr Glu Leu Lys Thr Glu Pro Phe Ser Ser Lys Ser Leu Leu 
    610                 615                 620                 


Glu Leu Glu Gln His Gln Thr Leu Leu Val Glu Gly Gln Glu Arg Lys 
625                 630                 635                 640 


Leu Leu Val Leu Gln Leu Met Ala Val Leu Cys Glu Arg Met Ser Glu 
                645                 650                 655     


Gln Ile Phe Thr Asn Val Thr Gln Val Val Asp Phe Val Ala Ala Thr 
            660                 665                 670         


Leu Gln Arg Ala Cys Ala Ser Leu Ala His Gln Ala Glu Ser Thr Val 
        675                 680                 685             


Glu Ser Gln Thr Leu Ser Met Ser Met Gly Leu Val Ala Val Met Leu 
    690                 695                 700                 


Gly Gly Ala Val Gln Leu Lys Ser Ser Asp Phe Ala Val Leu Lys Gln 
705                 710                 715                 720 


Leu Leu Pro Leu Leu Glu Lys Val Ser Asn Thr Tyr Pro Asp Pro Val 
                725                 730                 735     


Ile Gln Glu Leu Ala Val Asp Leu Arg Ile Thr Ile Ser Thr His Gly 
            740                 745                 750         


Ala Phe Ala Thr Glu Ala Val Ser Met Ala Ala Gln Ser Thr Leu Asn 
        755                 760                 765             


Arg Lys Asp Leu Glu Gly Lys Ile Glu Glu Gln Gln Gln Thr Ser His 
    770                 775                 780                 


Glu Arg Pro Thr Asp Val Ala His Ser His Leu Glu Gln Gln Gln Ser 
785                 790                 795                 800 


His Glu Thr Ala Pro Gln Thr Gly Leu Gln Ser Asn Ala Pro Ile Ile 
                805                 810                 815     


Pro Gln Gly Val Asn Glu Pro Ser Thr Thr Thr Ser Gln Lys Ser Gly 
            820                 825                 830         


Ser Val Thr Thr Glu Gln Leu Gln Glu Val Leu Leu Ser Ala Tyr Asp 
        835                 840                 845             


Pro Gln Ile Pro Thr Arg Ala Ala Ala Leu Arg Thr Leu Ser His Trp 
    850                 855                 860                 


Ile Glu Gln Arg Glu Ala Lys Ala Leu Glu Met Gln Glu Lys Leu Leu 
865                 870                 875                 880 


Lys Ile Phe Leu Glu Asn Leu Glu His Glu Asp Thr Phe Val Tyr Leu 
                885                 890                 895     


Ser Ala Ile Gln Gly Val Ala Leu Leu Ser Asp Val Tyr Pro Glu Lys 
            900                 905                 910         


Ile Leu Pro Asp Leu Leu Ala Gln Tyr Asp Ser Ser Lys Asp Lys His 
        915                 920                 925             


Thr Pro Glu Thr Arg Met Lys Val Gly Glu Val Leu Met Arg Ile Val 
    930                 935                 940                 


Arg Ala Leu Gly Asp Met Val Ser Lys Tyr Arg Glu Pro Leu Ile His 
945                 950                 955                 960 


Thr Phe Leu Arg Gly Val Arg Asp Pro Asp Gly Ala His Arg Ala Ser 
                965                 970                 975     


Ser Leu Ala Asn Leu Gly Glu Leu Cys Gln Arg Leu Asp Phe Leu Leu 
            980                 985                 990         


Gly Ser Val Val His Glu Val Thr  Ala Cys Leu Ile Ala  Val Ala Lys 
        995                 1000                 1005             


Thr Asp  Gly Glu Val Gln Val  Arg Arg Ala Ala Ile  His Val Val 
    1010                 1015                 1020             


Val Leu  Leu Leu Arg Gly Leu  Ser Gln Lys Ala Thr  Glu Val Leu 
    1025                 1030                 1035             


Ser Ala  Val Leu Lys Asp Leu  Tyr His Leu Leu Lys  His Val Val 
    1040                 1045                 1050             


Cys Leu  Glu Pro Asp Asp Val  Ala Lys Leu His Ala  Gln Leu Ala 
    1055                 1060                 1065             


Leu Glu  Glu Leu Asp Asp Ile  Met Lys Asn Phe Leu  Phe Pro Pro 
    1070                 1075                 1080             


Gln Lys  Leu Glu Lys Lys Ile  Met Val Leu Pro 
    1085                 1090                 


<210>  1451
<211>  205
<212>  PRT
<213>  Homo sapiens

<400>  1451

Met Ala Ala Ser Thr Ala Ser His Arg Pro Ile Lys Gly Ile Leu Lys 
1               5                   10                  15      


Asn Lys Thr Ser Thr Thr Ser Ser Met Val Ala Ser Ala Glu Gln Pro 
            20                  25                  30          


Arg Gly Asn Val Asp Glu Glu Leu Ser Lys Lys Ser Gln Lys Trp Asp 
        35                  40                  45              


Glu Met Asn Ile Leu Ala Thr Tyr His Pro Ala Asp Lys Asp Tyr Gly 
    50                  55                  60                  


Leu Met Lys Ile Asp Glu Pro Ser Thr Pro Tyr His Ser Met Met Gly 
65                  70                  75                  80  


Asp Asp Glu Asp Ala Cys Ser Asp Thr Glu Ala Thr Glu Ala Met Ala 
                85                  90                  95      


Pro Asp Ile Leu Ala Arg Lys Leu Ala Ala Ala Glu Gly Leu Glu Pro 
            100                 105                 110         


Lys Tyr Arg Ile Gln Glu Gln Glu Ser Ser Gly Glu Glu Asp Ser Asp 
        115                 120                 125             


Leu Ser Pro Glu Glu Arg Glu Lys Lys Arg Gln Phe Glu Met Lys Arg 
    130                 135                 140                 


Lys Leu His Tyr Asn Glu Gly Leu Asn Ile Lys Leu Ala Arg Gln Leu 
145                 150                 155                 160 


Ile Ser Lys Asp Leu His Asp Asp Asp Glu Asp Glu Glu Met Leu Glu 
                165                 170                 175     


Thr Ala Asp Gly Glu Ser Met Asn Thr Glu Glu Ser Asn Gln Gly Ser 
            180                 185                 190         


Thr Pro Ser Asp Gln Gln Gln Asn Lys Leu Arg Ser Ser 
        195                 200                 205 


<210>  1452
<211>  126
<212>  PRT
<213>  Homo sapiens

<400>  1452

Met Pro Glu Pro Ala Lys Ser Ala Pro Ala Pro Lys Lys Gly Ser Lys 
1               5                   10                  15      


Lys Ala Val Thr Lys Ala Gln Lys Lys Asp Gly Lys Lys Arg Lys Arg 
            20                  25                  30          


Ser Arg Lys Glu Ser Tyr Ser Ile Tyr Val Tyr Lys Val Leu Lys Gln 
        35                  40                  45              


Val His Pro Asp Thr Gly Ile Ser Ser Lys Ala Met Gly Ile Met Asn 
    50                  55                  60                  


Ser Phe Val Asn Asp Ile Phe Glu Arg Ile Ala Gly Glu Ala Ser Arg 
65                  70                  75                  80  


Leu Ala His Tyr Asn Lys Arg Ser Thr Ile Thr Ser Arg Glu Ile Gln 
                85                  90                  95      


Thr Ala Val Arg Leu Leu Leu Pro Gly Glu Leu Ala Lys His Ala Val 
            100                 105                 110         


Ser Glu Gly Thr Lys Ala Val Thr Lys Tyr Thr Ser Ser Lys 
        115                 120                 125     


<210>  1453
<211>  530
<212>  PRT
<213>  Homo sapiens

<400>  1453

Met Thr Arg Asp Phe Lys Pro Gly Asp Leu Ile Phe Ala Lys Met Lys 
1               5                   10                  15      


Gly Tyr Pro His Trp Pro Ala Arg Val Asp Glu Val Pro Asp Gly Ala 
            20                  25                  30          


Val Lys Pro Pro Thr Asn Lys Leu Pro Ile Phe Phe Phe Gly Thr His 
        35                  40                  45              


Glu Thr Ala Phe Leu Gly Pro Lys Asp Ile Phe Pro Tyr Ser Glu Asn 
    50                  55                  60                  


Lys Glu Lys Tyr Gly Lys Pro Asn Lys Arg Lys Gly Phe Asn Glu Gly 
65                  70                  75                  80  


Leu Trp Glu Ile Asp Asn Asn Pro Lys Val Lys Phe Ser Ser Gln Gln 
                85                  90                  95      


Ala Ala Thr Lys Gln Ser Asn Ala Ser Ser Asp Val Glu Val Glu Glu 
            100                 105                 110         


Lys Glu Thr Ser Val Ser Lys Glu Asp Thr Asp His Glu Glu Lys Ala 
        115                 120                 125             


Ser Asn Glu Asp Val Thr Lys Ala Val Asp Ile Thr Thr Pro Lys Ala 
    130                 135                 140                 


Ala Arg Arg Gly Arg Lys Arg Lys Ala Glu Lys Gln Val Glu Thr Glu 
145                 150                 155                 160 


Glu Ala Gly Val Val Thr Thr Ala Thr Ala Ser Val Asn Leu Lys Val 
                165                 170                 175     


Ser Pro Lys Arg Gly Arg Pro Ala Ala Thr Glu Val Lys Ile Pro Lys 
            180                 185                 190         


Pro Arg Gly Arg Pro Lys Met Val Lys Gln Pro Cys Pro Ser Glu Ser 
        195                 200                 205             


Asp Ile Ile Thr Glu Glu Asp Lys Ser Lys Lys Lys Gly Gln Glu Glu 
    210                 215                 220                 


Lys Gln Pro Lys Lys Gln Pro Lys Lys Asp Glu Glu Gly Gln Lys Glu 
225                 230                 235                 240 


Glu Asp Lys Pro Arg Lys Glu Pro Asp Lys Lys Glu Gly Lys Lys Glu 
                245                 250                 255     


Val Glu Ser Lys Arg Lys Asn Leu Ala Lys Thr Gly Val Thr Ser Thr 
            260                 265                 270         


Ser Asp Ser Glu Glu Glu Gly Asp Asp Gln Glu Gly Glu Lys Lys Arg 
        275                 280                 285             


Lys Gly Gly Arg Asn Phe Gln Thr Ala His Arg Arg Asn Met Leu Lys 
    290                 295                 300                 


Gly Gln His Glu Lys Glu Ala Ala Asp Arg Lys Arg Lys Gln Glu Glu 
305                 310                 315                 320 


Gln Met Glu Thr Glu Gln Gln Asn Lys Asp Glu Gly Lys Lys Pro Glu 
                325                 330                 335     


Val Lys Lys Val Glu Lys Lys Arg Glu Thr Ser Met Asp Ser Arg Leu 
            340                 345                 350         


Gln Arg Ile His Ala Glu Ile Lys Asn Ser Leu Lys Ile Asp Asn Leu 
        355                 360                 365             


Asp Val Asn Arg Cys Ile Glu Ala Leu Asp Glu Leu Ala Ser Leu Gln 
    370                 375                 380                 


Val Thr Met Gln Gln Ala Gln Lys His Thr Glu Met Ile Thr Thr Leu 
385                 390                 395                 400 


Lys Lys Ile Arg Arg Phe Lys Val Ser Gln Val Ile Met Glu Lys Ser 
                405                 410                 415     


Thr Met Leu Tyr Asn Lys Phe Lys Asn Met Phe Leu Val Gly Glu Gly 
            420                 425                 430         


Asp Ser Val Ile Thr Gln Val Leu Asn Lys Ser Leu Ala Glu Gln Arg 
        435                 440                 445             


Gln His Glu Glu Ala Asn Lys Thr Lys Asp Gln Gly Lys Lys Gly Pro 
    450                 455                 460                 


Asn Lys Lys Leu Glu Lys Glu Gln Thr Gly Ser Lys Thr Leu Asn Gly 
465                 470                 475                 480 


Gly Ser Asp Ala Gln Asp Gly Asn Gln Pro Gln His Asn Gly Glu Ser 
                485                 490                 495     


Asn Glu Asp Ser Lys Asp Asn His Glu Ala Ser Thr Lys Lys Lys Pro 
            500                 505                 510         


Ser Ser Glu Glu Arg Glu Thr Glu Ile Ser Leu Lys Asp Ser Thr Leu 
        515                 520                 525             


Asp Asn 
    530 


<210>  1454
<211>  385
<212>  PRT
<213>  Homo sapiens

<400>  1454

Met Ser Gly Ser Ser Gly Thr Pro Tyr Leu Gly Ser Lys Ile Ser Leu 
1               5                   10                  15      


Ile Ser Lys Ala Gln Ile Arg Tyr Glu Gly Ile Leu Tyr Thr Ile Asp 
            20                  25                  30          


Thr Asp Asn Ser Thr Val Ala Leu Ala Lys Val Arg Ser Phe Gly Thr 
        35                  40                  45              


Glu Asp Arg Pro Thr Asp Arg Pro Ala Pro Pro Arg Glu Glu Ile Tyr 
    50                  55                  60                  


Glu Tyr Ile Ile Phe Arg Gly Ser Asp Ile Lys Asp Ile Thr Val Cys 
65                  70                  75                  80  


Glu Pro Pro Lys Ala Gln His Thr Leu Pro Gln Asp Pro Ala Ile Val 
                85                  90                  95      


Gln Ser Ser Leu Gly Ser Ala Ser Ala Ser Pro Phe Gln Pro His Val 
            100                 105                 110         


Pro Tyr Ser Pro Phe Arg Gly Met Ala Pro Tyr Gly Pro Leu Ala Ala 
        115                 120                 125             


Ser Ser Leu Leu Ser Gln Gln Tyr Ala Ala Ser Leu Gly Leu Gly Ala 
    130                 135                 140                 


Gly Phe Pro Ser Ile Pro Val Gly Lys Ser Pro Met Val Glu Gln Ala 
145                 150                 155                 160 


Val Gln Thr Gly Ser Ala Asp Asn Leu Asn Ala Lys Lys Leu Leu Pro 
                165                 170                 175     


Gly Lys Gly Thr Thr Gly Thr Gln Leu Asn Gly Arg Gln Ala Gln Pro 
            180                 185                 190         


Ser Ser Lys Thr Ala Ser Asp Val Val Gln Pro Ala Ala Val Gln Ala 
        195                 200                 205             


Gln Gly Gln Val Asn Asp Glu Asn Arg Arg Pro Gln Arg Arg Arg Ser 
    210                 215                 220                 


Gly Asn Arg Arg Thr Arg Asn Arg Ser Arg Gly Gln Asn Arg Pro Thr 
225                 230                 235                 240 


Asn Val Lys Glu Asn Thr Ile Lys Phe Glu Gly Asp Phe Asp Phe Glu 
                245                 250                 255     


Ser Ala Asn Ala Gln Phe Asn Arg Glu Glu Leu Asp Lys Glu Phe Lys 
            260                 265                 270         


Lys Lys Leu Asn Phe Lys Asp Asp Lys Ala Glu Lys Gly Glu Glu Lys 
        275                 280                 285             


Asp Leu Ala Val Val Thr Gln Ser Ala Glu Ala Pro Ala Glu Glu Asp 
    290                 295                 300                 


Leu Leu Gly Pro Asn Cys Tyr Tyr Asp Lys Ser Lys Ser Phe Phe Asp 
305                 310                 315                 320 


Asn Ile Ser Ser Glu Leu Lys Thr Ser Ser Arg Arg Thr Thr Trp Ala 
                325                 330                 335     


Glu Glu Arg Lys Leu Asn Thr Glu Thr Phe Gly Val Ser Gly Arg Phe 
            340                 345                 350         


Leu Arg Gly Arg Ser Ser Arg Gly Gly Phe Arg Gly Gly Arg Gly Asn 
        355                 360                 365             


Gly Thr Thr Arg Arg Asn Pro Thr Ser His Arg Ala Gly Thr Gly Arg 
    370                 375                 380                 


Val 
385 


<210>  1455
<211>  431
<212>  PRT
<213>  Homo sapiens

<400>  1455

Met His Val Arg Ser Leu Arg Ala Ala Ala Pro His Ser Phe Val Ala 
1               5                   10                  15      


Leu Trp Ala Pro Leu Phe Leu Leu Arg Ser Ala Leu Ala Asp Phe Ser 
            20                  25                  30          


Leu Asp Asn Glu Val His Ser Ser Phe Ile His Arg Arg Leu Arg Ser 
        35                  40                  45              


Gln Glu Arg Arg Glu Met Gln Arg Glu Ile Leu Ser Ile Leu Gly Leu 
    50                  55                  60                  


Pro His Arg Pro Arg Pro His Leu Gln Gly Lys His Asn Ser Ala Pro 
65                  70                  75                  80  


Met Phe Met Leu Asp Leu Tyr Asn Ala Met Ala Val Glu Glu Gly Gly 
                85                  90                  95      


Gly Pro Gly Gly Gln Gly Phe Ser Tyr Pro Tyr Lys Ala Val Phe Ser 
            100                 105                 110         


Thr Gln Gly Pro Pro Leu Ala Ser Leu Gln Asp Ser His Phe Leu Thr 
        115                 120                 125             


Asp Ala Asp Met Val Met Ser Phe Val Asn Leu Val Glu His Asp Lys 
    130                 135                 140                 


Glu Phe Phe His Pro Arg Tyr His His Arg Glu Phe Arg Phe Asp Leu 
145                 150                 155                 160 


Ser Lys Ile Pro Glu Gly Glu Ala Val Thr Ala Ala Glu Phe Arg Ile 
                165                 170                 175     


Tyr Lys Asp Tyr Ile Arg Glu Arg Phe Asp Asn Glu Thr Phe Arg Ile 
            180                 185                 190         


Ser Val Tyr Gln Val Leu Gln Glu His Leu Gly Arg Glu Ser Asp Leu 
        195                 200                 205             


Phe Leu Leu Asp Ser Arg Thr Leu Trp Ala Ser Glu Glu Gly Trp Leu 
    210                 215                 220                 


Val Phe Asp Ile Thr Ala Thr Ser Asn His Trp Val Val Asn Pro Arg 
225                 230                 235                 240 


His Asn Leu Gly Leu Gln Leu Ser Val Glu Thr Leu Asp Gly Gln Ser 
                245                 250                 255     


Ile Asn Pro Lys Leu Ala Gly Leu Ile Gly Arg His Gly Pro Gln Asn 
            260                 265                 270         


Lys Gln Pro Phe Met Val Ala Phe Phe Lys Ala Thr Glu Val His Phe 
        275                 280                 285             


Arg Ser Ile Arg Ser Thr Gly Ser Lys Gln Arg Ser Gln Asn Arg Ser 
    290                 295                 300                 


Lys Thr Pro Lys Asn Gln Glu Ala Leu Arg Met Ala Asn Val Ala Glu 
305                 310                 315                 320 


Asn Ser Ser Ser Asp Gln Arg Gln Ala Cys Lys Lys His Glu Leu Tyr 
                325                 330                 335     


Val Ser Phe Arg Asp Leu Gly Trp Gln Asp Trp Ile Ile Ala Pro Glu 
            340                 345                 350         


Gly Tyr Ala Ala Tyr Tyr Cys Glu Gly Glu Cys Ala Phe Pro Leu Asn 
        355                 360                 365             


Ser Tyr Met Asn Ala Thr Asn His Ala Ile Val Gln Thr Leu Val His 
    370                 375                 380                 


Phe Ile Asn Pro Glu Thr Val Pro Lys Pro Cys Cys Ala Pro Thr Gln 
385                 390                 395                 400 


Leu Asn Ala Ile Ser Val Leu Tyr Phe Asp Asp Ser Ser Asn Val Ile 
                405                 410                 415     


Leu Lys Lys Tyr Arg Asn Met Val Val Arg Ala Cys Gly Cys His 
            420                 425                 430     


<210>  1456
<211>  268
<212>  PRT
<213>  Homo sapiens

<400>  1456

Met Glu Val Thr Gly Asp Ala Gly Val Pro Glu Ser Gly Glu Ile Arg 
1               5                   10                  15      


Thr Leu Lys Pro Cys Leu Leu Arg Arg Asn Tyr Ser Arg Glu Gln His 
            20                  25                  30          


Gly Val Ala Ala Ser Cys Leu Glu Asp Leu Arg Ser Lys Ala Cys Asp 
        35                  40                  45              


Ile Leu Ala Ile Asp Lys Ser Leu Thr Pro Val Thr Leu Val Leu Ala 
    50                  55                  60                  


Glu Asp Gly Thr Ile Val Asp Asp Asp Asp Tyr Phe Leu Cys Leu Pro 
65                  70                  75                  80  


Ser Asn Thr Lys Phe Val Ala Leu Ala Ser Asn Glu Lys Trp Ala Tyr 
                85                  90                  95      


Asn Asn Ser Asp Gly Gly Thr Ala Trp Ile Ser Gln Glu Ser Phe Asp 
            100                 105                 110         


Val Asp Glu Thr Asp Ser Gly Ala Gly Leu Lys Trp Lys Asn Val Ala 
        115                 120                 125             


Arg Gln Leu Lys Glu Asp Leu Ser Ser Ile Ile Leu Leu Ser Glu Glu 
    130                 135                 140                 


Asp Leu Gln Met Leu Val Asp Ala Pro Cys Ser Asp Leu Ala Gln Glu 
145                 150                 155                 160 


Leu Arg Gln Ser Cys Ala Thr Val Gln Arg Leu Gln His Thr Leu Gln 
                165                 170                 175     


Gln Val Leu Asp Gln Arg Glu Glu Val Arg Gln Ser Lys Gln Leu Leu 
            180                 185                 190         


Gln Leu Tyr Leu Gln Ala Leu Glu Lys Glu Gly Ser Leu Leu Ser Lys 
        195                 200                 205             


Gln Glu Glu Ser Lys Ala Ala Phe Gly Glu Glu Val Asp Ala Val Asp 
    210                 215                 220                 


Thr Gly Ile Ser Arg Glu Thr Ser Ser Asp Val Ala Leu Ala Ser His 
225                 230                 235                 240 


Ile Leu Thr Ala Leu Arg Glu Lys Gln Ala Pro Glu Leu Ser Leu Ser 
                245                 250                 255     


Ser Gln Asp Leu Glu Val Gly Gly Asn Gln Gly His 
            260                 265             


<210>  1457
<211>  1077
<212>  PRT
<213>  Homo sapiens

<400>  1457

Met Glu Pro Ser Leu Lys Tyr Ile Asn Lys Lys Phe Pro Asn Ile Asp 
1               5                   10                  15      


Val Arg Asn Ser Thr Gln His Leu Gly Pro Val His Arg Glu Lys Ala 
            20                  25                  30          


Glu Ile Ile Arg Phe Leu Thr Asn Tyr Tyr Gln Ser Phe Val Asp Val 
        35                  40                  45              


Met Glu Phe Arg Asp His Val Tyr Glu Leu Leu Asn Thr Ile Asp Ala 
    50                  55                  60                  


Cys Gln Cys His Phe Asp Ile Asn Leu Asn Phe Asp Phe Thr Arg Ser 
65                  70                  75                  80  


Tyr Leu Asp Leu Ile Val Thr Tyr Thr Ser Val Ile Leu Leu Leu Ser 
                85                  90                  95      


Arg Ile Glu Asp Arg Arg Ile Leu Ile Gly Met Tyr Asn Cys Ala His 
            100                 105                 110         


Glu Met Leu His Gly His Gly Asp Pro Ser Phe Ala Arg Leu Gly Gln 
        115                 120                 125             


Met Val Leu Glu Tyr Asp His Pro Leu Lys Lys Leu Thr Glu Glu Phe 
    130                 135                 140                 


Gly Pro His Thr Lys Ala Val Ser Gly Ala Leu Leu Ser Leu His Phe 
145                 150                 155                 160 


Leu Phe Val Arg Arg Asn Gln Gly Ala Glu Gln Trp Arg Ser Ala Gln 
                165                 170                 175     


Leu Leu Ser Leu Ile Ser Asn Pro Pro Ala Met Ile Asn Pro Ala Asn 
            180                 185                 190         


Ser Asp Thr Met Ala Cys Glu Tyr Leu Ser Val Glu Val Met Glu Arg 
        195                 200                 205             


Trp Ile Ile Ile Gly Phe Leu Leu Cys His Gly Cys Leu Asn Ser Asn 
    210                 215                 220                 


Ser Gln Cys Gln Lys Leu Trp Lys Leu Cys Leu Gln Gly Ser Leu Tyr 
225                 230                 235                 240 


Ile Thr Leu Ile Arg Glu Asp Val Leu Gln Val His Lys Val Thr Glu 
                245                 250                 255     


Asp Leu Phe Ser Ser Leu Lys Gly Tyr Gly Lys Arg Val Ala Asp Ile 
            260                 265                 270         


Lys Glu Ser Lys Glu His Val Ile Ala Asn Ser Gly Gln Phe His Cys 
        275                 280                 285             


Gln Arg Arg Gln Phe Leu Arg Met Ala Val Lys Glu Leu Glu Thr Val 
    290                 295                 300                 


Leu Ala Asp Glu Pro Gly Leu Leu Gly Pro Lys Ala Leu Phe Ala Phe 
305                 310                 315                 320 


Met Ala Leu Ser Phe Ile Arg Asp Glu Val Thr Trp Leu Val Arg His 
                325                 330                 335     


Thr Glu Asn Val Thr Lys Thr Lys Thr Pro Glu Asp Tyr Ala Asp Ser 
            340                 345                 350         


Ser Ile Ala Glu Leu Leu Phe Leu Leu Glu Gly Ile Arg Ser Leu Val 
        355                 360                 365             


Arg Arg His Ile Lys Val Ile Gln Gln Tyr His Leu Gln Tyr Leu Ala 
    370                 375                 380                 


Arg Phe Asp Ala Leu Val Leu Ser Asp Ile Ile Gln Asn Leu Ser Val 
385                 390                 395                 400 


Cys Pro Glu Glu Glu Ser Ile Ile Met Ser Ser Phe Val Ser Ile Leu 
                405                 410                 415     


Ser Ser Leu Asn Leu Lys Gln Val Asp Asn Gly Glu Lys Phe Glu Phe 
            420                 425                 430         


Ser Gly Leu Arg Leu Asp Trp Phe Arg Leu Gln Ala Tyr Thr Ser Val 
        435                 440                 445             


Ala Lys Ala Pro Leu His Leu His Glu Asn Pro Asp Leu Ala Lys Val 
    450                 455                 460                 


Met Asn Leu Ile Val Phe His Ser Arg Met Leu Asp Ser Val Glu Lys 
465                 470                 475                 480 


Leu Leu Val Glu Thr Ser Asp Leu Ser Thr Phe Cys Phe His Leu Arg 
                485                 490                 495     


Ile Phe Glu Lys Met Phe Ala Met Thr Leu Glu Glu Ser Ala Met Leu 
            500                 505                 510         


Arg Tyr Ala Ile Ala Phe Pro Leu Ile Cys Ala His Phe Val His Cys 
        515                 520                 525             


Thr His Glu Met Cys Pro Glu Glu Tyr Pro His Leu Lys Asn His Gly 
    530                 535                 540                 


Leu His His Cys Asn Ser Phe Leu Glu Glu Leu Ala Lys Gln Thr Ser 
545                 550                 555                 560 


Asn Cys Val Leu Glu Ile Cys Ala Glu Gln Arg Asn Leu Ser Glu Gln 
                565                 570                 575     


Leu Leu Pro Lys His Cys Ala Thr Thr Ile Ser Lys Ala Lys Asn Lys 
            580                 585                 590         


Lys Thr Arg Lys Gln Arg Gln Thr Pro Arg Lys Gly Glu Pro Glu Arg 
        595                 600                 605             


Asp Lys Pro Gly Ala Glu Ser His Arg Lys Asn Arg Ser Ile Val Thr 
    610                 615                 620                 


Asn Met Asp Lys Leu His Leu Asn Leu Thr Glu Leu Ala Leu Thr Met 
625                 630                 635                 640 


Asn His Val Tyr Ser Phe Ser Val Phe Glu His Thr Ile Phe Pro Ser 
                645                 650                 655     


Glu Tyr Leu Ser Ser His Leu Glu Ala Arg Leu Asn Arg Ala Ile Val 
            660                 665                 670         


Trp Leu Ala Gly Tyr Asn Ala Thr Thr Gln Glu Ile Val Arg Pro Ser 
        675                 680                 685             


Glu Leu Leu Ala Gly Val Lys Ala Tyr Ile Gly Phe Ile Gln Ser Leu 
    690                 695                 700                 


Ala Gln Phe Leu Gly Ala Asp Ala Ser Arg Val Ile Arg Asn Ala Leu 
705                 710                 715                 720 


Leu Gln Gln Thr Gln Pro Leu Asp Ser Cys Gly Glu Gln Thr Ile Thr 
                725                 730                 735     


Thr Leu Tyr Thr Asn Trp Tyr Leu Glu Ser Leu Leu Arg Gln Ala Ser 
            740                 745                 750         


Ser Gly Thr Ile Ile Leu Ser Pro Ala Met Gln Ala Phe Val Ser Leu 
        755                 760                 765             


Pro Arg Glu Gly Glu Gln Asn Phe Ser Ala Glu Glu Phe Ser Asp Ile 
    770                 775                 780                 


Ser Glu Met Arg Ala Leu Ala Glu Leu Leu Gly Pro Tyr Gly Met Lys 
785                 790                 795                 800 


Phe Leu Ser Glu Asn Leu Met Trp His Val Thr Ser Gln Ile Val Glu 
                805                 810                 815     


Leu Lys Lys Leu Val Val Glu Asn Met Asp Ile Leu Val Gln Ile Arg 
            820                 825                 830         


Ser Asn Phe Ser Lys Pro Asp Leu Met Ala Ser Leu Leu Pro Gln Leu 
        835                 840                 845             


Thr Gly Ala Glu Asn Val Leu Lys Arg Met Thr Ile Ile Gly Val Ile 
    850                 855                 860                 


Leu Ser Phe Arg Ala Met Ala Gln Glu Gly Leu Arg Glu Val Phe Ser 
865                 870                 875                 880 


Ser His Cys Pro Phe Leu Met Gly Pro Ile Glu Cys Leu Lys Glu Phe 
                885                 890                 895     


Val Thr Pro Asp Thr Asp Ile Lys Val Thr Leu Ser Ile Phe Glu Leu 
            900                 905                 910         


Ala Ser Ala Ala Gly Val Gly Cys Asp Ile Asp Pro Ala Leu Val Ala 
        915                 920                 925             


Ala Ile Ala Asn Leu Lys Ala Asp Thr Ser Ser Pro Glu Glu Glu Tyr 
    930                 935                 940                 


Lys Val Ala Cys Leu Leu Leu Ile Phe Leu Ala Val Ser Leu Pro Leu 
945                 950                 955                 960 


Leu Ala Thr Asp Pro Ser Ser Phe Tyr Ser Ile Glu Lys Asp Gly Tyr 
                965                 970                 975     


Asn Asn Asn Ile His Cys Leu Thr Lys Ala Ile Ile Gln Val Ser Ala 
            980                 985                 990         


Ala Leu Phe Thr Leu Tyr Asn Lys  Asn Ile Glu Thr His  Leu Lys Glu 
        995                 1000                 1005             


Phe Leu  Val Val Ala Ser Val  Ser Leu Leu Gln Leu  Gly Gln Glu 
    1010                 1015                 1020             


Thr Asp  Lys Leu Lys Thr Arg  Asn Arg Glu Ser Ile  Ser Leu Leu 
    1025                 1030                 1035             


Met Arg  Leu Val Val Glu Glu  Ser Ser Phe Leu Thr  Leu Asp Met 
    1040                 1045                 1050             


Leu Glu  Ser Cys Phe Pro Tyr  Val Leu Leu Arg Asn  Ala Tyr Arg 
    1055                 1060                 1065             


Glu Val  Ser Arg Ala Phe His  Leu Asn 
    1070                 1075         


<210>  1458
<211>  304
<212>  PRT
<213>  Homo sapiens

<400>  1458

Met Met Lys Lys Asp Ala Leu Thr Leu Ser Leu Ser Glu Gln Val Ala 
1               5                   10                  15      


Ala Ala Leu Lys Pro Ala Ala Ala Pro Pro Pro Thr Pro Leu Arg Ala 
            20                  25                  30          


Asp Gly Ala Pro Ser Ala Ala Pro Pro Asp Gly Leu Leu Ala Ser Pro 
        35                  40                  45              


Asp Leu Gly Leu Leu Lys Leu Ala Ser Pro Glu Leu Glu Arg Leu Ile 
    50                  55                  60                  


Ile Gln Ser Asn Gly Leu Val Thr Thr Thr Pro Thr Ser Ser Gln Phe 
65                  70                  75                  80  


Leu Tyr Pro Lys Val Ala Ala Ser Glu Glu Gln Glu Phe Ala Glu Gly 
                85                  90                  95      


Phe Val Lys Ala Leu Glu Asp Leu His Lys Gln Asn Gln Leu Gly Ala 
            100                 105                 110         


Gly Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Gly Gly Pro Ser Gly 
        115                 120                 125             


Thr Ala Thr Gly Ser Ala Pro Pro Gly Glu Leu Ala Pro Ala Ala Ala 
    130                 135                 140                 


Ala Pro Glu Ala Pro Val Tyr Ala Asn Leu Ser Ser Tyr Ala Gly Gly 
145                 150                 155                 160 


Ala Gly Gly Ala Gly Gly Ala Ala Thr Val Ala Phe Ala Ala Glu Pro 
                165                 170                 175     


Val Pro Phe Pro Pro Pro Pro Pro Pro Gly Ala Leu Gly Pro Pro Arg 
            180                 185                 190         


Leu Ala Ala Leu Lys Asp Glu Pro Gln Thr Val Pro Asp Val Pro Ser 
        195                 200                 205             


Phe Gly Glu Ser Pro Pro Leu Ser Pro Ile Asp Met Asp Thr Gln Glu 
    210                 215                 220                 


Arg Ile Lys Ala Glu Arg Lys Arg Leu Arg Asn Arg Ile Ala Ala Ser 
225                 230                 235                 240 


Lys Cys Arg Lys Arg Lys Leu Glu Arg Ile Ser Arg Leu Glu Glu Lys 
                245                 250                 255     


Val Lys Thr Leu Lys Ser Gln Asn Thr Glu Leu Ala Ser Thr Ala Ser 
            260                 265                 270         


Leu Leu Arg Glu Gln Val Ala Gln Leu Lys Gln Lys Val Leu Ser His 
        275                 280                 285             


Val Asn Ser Gly Cys Gln Leu Leu Pro Gln His Gln Val Pro Ala Tyr 
    290                 295                 300                 


<210>  1459
<211>  323
<212>  PRT
<213>  Homo sapiens

<400>  1459

Met Ala Tyr Val Pro Ala Pro Gly Tyr Gln Pro Thr Tyr Asn Pro Thr 
1               5                   10                  15      


Leu Pro Tyr Tyr Gln Pro Ile Pro Gly Gly Leu Asn Val Gly Met Ser 
            20                  25                  30          


Val Tyr Ile Gln Gly Val Ala Ser Glu His Met Lys Arg Phe Phe Val 
        35                  40                  45              


Asn Phe Val Val Gly Gln Asp Pro Gly Ser Asp Val Ala Phe His Phe 
    50                  55                  60                  


Asn Pro Arg Phe Asp Gly Trp Asp Lys Val Val Phe Asn Thr Leu Gln 
65                  70                  75                  80  


Gly Gly Lys Trp Gly Ser Glu Glu Arg Lys Arg Ser Met Pro Phe Lys 
                85                  90                  95      


Lys Gly Ala Ala Phe Glu Leu Val Phe Ile Val Leu Ala Glu His Tyr 
            100                 105                 110         


Lys Val Val Val Asn Gly Asn Pro Phe Tyr Glu Tyr Gly His Arg Leu 
        115                 120                 125             


Pro Leu Gln Met Val Thr His Leu Gln Val Asp Gly Asp Leu Gln Leu 
    130                 135                 140                 


Gln Ser Ile Asn Phe Ile Gly Gly Gln Pro Leu Arg Pro Gln Gly Pro 
145                 150                 155                 160 


Pro Met Met Pro Pro Tyr Pro Gly Pro Gly His Cys His Gln Gln Leu 
                165                 170                 175     


Asn Ser Leu Pro Thr Met Glu Gly Pro Pro Thr Phe Asn Pro Pro Val 
            180                 185                 190         


Pro Tyr Phe Gly Arg Leu Gln Gly Gly Leu Thr Ala Arg Arg Thr Ile 
        195                 200                 205             


Ile Ile Lys Gly Tyr Val Pro Pro Thr Gly Lys Ser Phe Ala Ile Asn 
    210                 215                 220                 


Phe Lys Val Gly Ser Ser Gly Asp Ile Ala Leu His Ile Asn Pro Arg 
225                 230                 235                 240 


Met Gly Asn Gly Thr Val Val Arg Asn Ser Leu Leu Asn Gly Ser Trp 
                245                 250                 255     


Gly Ser Glu Glu Lys Lys Ile Thr His Asn Pro Phe Gly Pro Gly Gln 
            260                 265                 270         


Phe Phe Asp Leu Ser Ile Arg Cys Gly Leu Asp Arg Phe Lys Val Tyr 
        275                 280                 285             


Ala Asn Gly Gln His Leu Phe Asp Phe Ala His Arg Leu Ser Ala Phe 
    290                 295                 300                 


Gln Arg Val Asp Thr Leu Glu Ile Gln Gly Asp Val Thr Leu Ser Tyr 
305                 310                 315                 320 


Val Gln Ile 
            


<210>  1460
<211>  943
<212>  PRT
<213>  Homo sapiens

<400>  1460

Met Ala Arg Gly Ser Ala Leu Pro Arg Arg Pro Leu Leu Cys Ile Pro 
1               5                   10                  15      


Ala Val Trp Ala Ala Ala Ala Leu Leu Leu Ser Val Ser Arg Thr Ser 
            20                  25                  30          


Gly Glu Val Glu Val Leu Asp Pro Asn Asp Pro Leu Gly Pro Leu Asp 
        35                  40                  45              


Gly Gln Asp Gly Pro Ile Pro Thr Leu Lys Gly Tyr Phe Leu Asn Phe 
    50                  55                  60                  


Leu Glu Pro Val Asn Asn Ile Thr Ile Val Gln Gly Gln Thr Ala Ile 
65                  70                  75                  80  


Leu His Cys Lys Val Ala Gly Asn Pro Pro Pro Asn Val Arg Trp Leu 
                85                  90                  95      


Lys Asn Asp Ala Pro Val Val Gln Glu Pro Arg Arg Ile Ile Ile Arg 
            100                 105                 110         


Lys Thr Glu Tyr Gly Ser Arg Leu Arg Ile Gln Asp Leu Asp Thr Thr 
        115                 120                 125             


Asp Thr Gly Tyr Tyr Gln Cys Val Ala Thr Asn Gly Met Lys Thr Ile 
    130                 135                 140                 


Thr Ala Thr Gly Val Leu Phe Val Arg Leu Gly Pro Thr His Ser Pro 
145                 150                 155                 160 


Asn His Asn Phe Gln Asp Asp Tyr His Glu Asp Gly Phe Cys Gln Pro 
                165                 170                 175     


Tyr Arg Gly Ile Ala Cys Ala Arg Phe Ile Gly Asn Arg Thr Ile Tyr 
            180                 185                 190         


Val Asp Ser Leu Gln Met Gln Gly Glu Ile Glu Asn Arg Ile Thr Ala 
        195                 200                 205             


Ala Phe Thr Met Ile Gly Thr Ser Thr His Leu Ser Asp Gln Cys Ser 
    210                 215                 220                 


Gln Phe Ala Ile Pro Ser Phe Cys His Phe Val Phe Pro Leu Cys Asp 
225                 230                 235                 240 


Ala Arg Ser Arg Thr Pro Lys Pro Arg Glu Leu Cys Arg Asp Glu Cys 
                245                 250                 255     


Glu Val Leu Glu Ser Asp Leu Cys Arg Gln Glu Tyr Thr Ile Ala Arg 
            260                 265                 270         


Ser Asn Pro Leu Ile Leu Met Arg Leu Gln Leu Pro Lys Cys Glu Ala 
        275                 280                 285             


Leu Pro Met Pro Glu Ser Pro Asp Ala Ala Asn Cys Met Arg Ile Gly 
    290                 295                 300                 


Ile Pro Ala Glu Arg Leu Gly Arg Tyr His Gln Cys Tyr Asn Gly Ser 
305                 310                 315                 320 


Gly Met Asp Tyr Arg Gly Thr Ala Ser Thr Thr Lys Ser Gly His Gln 
                325                 330                 335     


Cys Gln Pro Trp Ala Leu Gln His Pro His Ser His His Leu Ser Ser 
            340                 345                 350         


Thr Asp Phe Pro Glu Leu Gly Gly Gly His Ala Tyr Cys Arg Asn Pro 
        355                 360                 365             


Gly Gly Gln Met Glu Gly Pro Trp Cys Phe Thr Gln Asn Lys Asn Val 
    370                 375                 380                 


Arg Met Glu Leu Cys Asp Val Pro Ser Cys Ser Pro Arg Asp Ser Ser 
385                 390                 395                 400 


Lys Met Gly Ile Leu Tyr Ile Leu Val Pro Ser Ile Ala Ile Pro Leu 
                405                 410                 415     


Val Ile Ala Cys Leu Phe Phe Leu Val Cys Met Cys Arg Asn Lys Gln 
            420                 425                 430         


Lys Ala Ser Ala Ser Thr Pro Gln Arg Arg Gln Leu Met Ala Ser Pro 
        435                 440                 445             


Ser Gln Asp Met Glu Met Pro Leu Ile Asn Gln His Lys Gln Ala Lys 
    450                 455                 460                 


Leu Lys Glu Ile Ser Leu Ser Ala Val Arg Phe Met Glu Glu Leu Gly 
465                 470                 475                 480 


Glu Asp Arg Phe Gly Lys Val Tyr Lys Gly His Leu Phe Gly Pro Ala 
                485                 490                 495     


Pro Gly Glu Gln Thr Gln Ala Val Ala Ile Lys Thr Leu Lys Asp Lys 
            500                 505                 510         


Ala Glu Gly Pro Leu Arg Glu Glu Phe Arg His Glu Ala Met Leu Arg 
        515                 520                 525             


Ala Arg Leu Gln His Pro Asn Val Val Cys Leu Leu Gly Val Val Thr 
    530                 535                 540                 


Lys Asp Gln Pro Leu Ser Met Ile Phe Ser Tyr Cys Ser His Gly Asp 
545                 550                 555                 560 


Leu His Glu Phe Leu Val Met Arg Ser Pro His Ser Asp Val Gly Ser 
                565                 570                 575     


Thr Asp Asp Asp Arg Thr Val Lys Ser Ala Leu Glu Pro Pro Asp Phe 
            580                 585                 590         


Val His Leu Val Ala Gln Ile Ala Ala Gly Met Glu Tyr Leu Ser Ser 
        595                 600                 605             


His His Val Val His Lys Asp Leu Ala Thr Arg Asn Val Leu Val Tyr 
    610                 615                 620                 


Asp Lys Leu Asn Val Lys Ile Ser Asp Leu Gly Leu Phe Arg Glu Val 
625                 630                 635                 640 


Tyr Ala Ala Asp Tyr Tyr Lys Leu Leu Gly Asn Ser Leu Leu Pro Ile 
                645                 650                 655     


Arg Trp Met Ala Pro Glu Ala Ile Met Tyr Gly Lys Phe Ser Ile Asp 
            660                 665                 670         


Ser Asp Ile Trp Ser Tyr Gly Val Val Leu Trp Glu Val Phe Ser Tyr 
        675                 680                 685             


Gly Leu Gln Pro Tyr Cys Gly Tyr Ser Asn Gln Asp Val Val Glu Met 
    690                 695                 700                 


Ile Arg Asn Arg Gln Val Leu Pro Cys Pro Asp Asp Cys Pro Ala Trp 
705                 710                 715                 720 


Val Tyr Ala Leu Met Ile Glu Cys Trp Asn Glu Phe Pro Ser Arg Arg 
                725                 730                 735     


Pro Arg Phe Lys Asp Ile His Ser Arg Leu Arg Ala Trp Gly Asn Leu 
            740                 745                 750         


Ser Asn Tyr Asn Ser Ser Ala Gln Thr Ser Gly Ala Ser Asn Thr Thr 
        755                 760                 765             


Gln Thr Ser Ser Leu Ser Thr Ser Pro Val Ser Asn Val Ser Asn Ala 
    770                 775                 780                 


Arg Tyr Val Gly Pro Lys Gln Lys Ala Pro Pro Phe Pro Gln Pro Gln 
785                 790                 795                 800 


Phe Ile Pro Met Lys Gly Gln Ile Arg Pro Met Val Pro Pro Pro Gln 
                805                 810                 815     


Leu Tyr Val Pro Val Asn Gly Tyr Gln Pro Val Pro Ala Tyr Gly Ala 
            820                 825                 830         


Tyr Leu Pro Asn Phe Tyr Pro Val Gln Ile Pro Met Gln Met Ala Pro 
        835                 840                 845             


Gln Gln Val Pro Pro Gln Met Val Pro Lys Pro Ser Ser His His Ser 
    850                 855                 860                 


Gly Ser Gly Ser Thr Ser Thr Gly Tyr Val Thr Thr Ala Pro Ser Asn 
865                 870                 875                 880 


Thr Ser Met Ala Asp Arg Ala Ala Leu Leu Ser Glu Gly Ala Asp Asp 
                885                 890                 895     


Thr Gln Asn Ala Pro Glu Asp Gly Ala Gln Ser Thr Val Gln Glu Ala 
            900                 905                 910         


Glu Glu Glu Glu Glu Gly Ser Val Pro Glu Thr Glu Leu Leu Gly Asp 
        915                 920                 925             


Cys Asp Thr Leu Gln Val Asp Glu Ala Gln Val Gln Leu Glu Ala 
    930                 935                 940             


<210>  1461
<211>  419
<212>  PRT
<213>  Homo sapiens

<400>  1461

Met His Leu Leu Gly Phe Phe Ser Val Ala Cys Ser Leu Leu Ala Ala 
1               5                   10                  15      


Ala Leu Leu Pro Gly Pro Arg Glu Ala Pro Ala Ala Ala Ala Ala Phe 
            20                  25                  30          


Glu Ser Gly Leu Asp Leu Ser Asp Ala Glu Pro Asp Ala Gly Glu Ala 
        35                  40                  45              


Thr Ala Tyr Ala Ser Lys Asp Leu Glu Glu Gln Leu Arg Ser Val Ser 
    50                  55                  60                  


Ser Val Asp Glu Leu Met Thr Val Leu Tyr Pro Glu Tyr Trp Lys Met 
65                  70                  75                  80  


Tyr Lys Cys Gln Leu Arg Lys Gly Gly Trp Gln His Asn Arg Glu Gln 
                85                  90                  95      


Ala Asn Leu Asn Ser Arg Thr Glu Glu Thr Ile Lys Phe Ala Ala Ala 
            100                 105                 110         


His Tyr Asn Thr Glu Ile Leu Lys Ser Ile Asp Asn Glu Trp Arg Lys 
        115                 120                 125             


Thr Gln Cys Met Pro Arg Glu Val Cys Ile Asp Val Gly Lys Glu Phe 
    130                 135                 140                 


Gly Val Ala Thr Asn Thr Phe Phe Lys Pro Pro Cys Val Ser Val Tyr 
145                 150                 155                 160 


Arg Cys Gly Gly Cys Cys Asn Ser Glu Gly Leu Gln Cys Met Asn Thr 
                165                 170                 175     


Ser Thr Ser Tyr Leu Ser Lys Thr Leu Phe Glu Ile Thr Val Pro Leu 
            180                 185                 190         


Ser Gln Gly Pro Lys Pro Val Thr Ile Ser Phe Ala Asn His Thr Ser 
        195                 200                 205             


Cys Arg Cys Met Ser Lys Leu Asp Val Tyr Arg Gln Val His Ser Ile 
    210                 215                 220                 


Ile Arg Arg Ser Leu Pro Ala Thr Leu Pro Gln Cys Gln Ala Ala Asn 
225                 230                 235                 240 


Lys Thr Cys Pro Thr Asn Tyr Met Trp Asn Asn His Ile Cys Arg Cys 
                245                 250                 255     


Leu Ala Gln Glu Asp Phe Met Phe Ser Ser Asp Ala Gly Asp Asp Ser 
            260                 265                 270         


Thr Asp Gly Phe His Asp Ile Cys Gly Pro Asn Lys Glu Leu Asp Glu 
        275                 280                 285             


Glu Thr Cys Gln Cys Val Cys Arg Ala Gly Leu Arg Pro Ala Ser Cys 
    290                 295                 300                 


Gly Pro His Lys Glu Leu Asp Arg Asn Ser Cys Gln Cys Val Cys Lys 
305                 310                 315                 320 


Asn Lys Leu Phe Pro Ser Gln Cys Gly Ala Asn Arg Glu Phe Asp Glu 
                325                 330                 335     


Asn Thr Cys Gln Cys Val Cys Lys Arg Thr Cys Pro Arg Asn Gln Pro 
            340                 345                 350         


Leu Asn Pro Gly Lys Cys Ala Cys Glu Cys Thr Glu Ser Pro Gln Lys 
        355                 360                 365             


Cys Leu Leu Lys Gly Lys Lys Phe His His Gln Thr Cys Ser Cys Tyr 
    370                 375                 380                 


Arg Arg Pro Cys Thr Asn Arg Gln Lys Ala Cys Glu Pro Gly Phe Ser 
385                 390                 395                 400 


Tyr Ser Glu Glu Val Cys Arg Cys Val Pro Ser Tyr Trp Lys Arg Pro 
                405                 410                 415     


Gln Met Ser 
            


<210>  1462
<211>  713
<212>  PRT
<213>  Homo sapiens

<400>  1462

Met Gly Ser Ala Glu Met Cys Arg Asp Leu Ala Pro Glu Val Glu Lys 
1               5                   10                  15      


Leu Leu Leu Gln Pro Ser Pro Tyr Val Arg Lys Lys Ala Ile Leu Thr 
            20                  25                  30          


Ala Val His Met Ile Arg Lys Val Pro Glu Leu Ser Ser Val Phe Leu 
        35                  40                  45              


Pro Pro Cys Ala Gln Leu Leu His Glu Arg His His Gly Lys Ala Val 
    50                  55                  60                  


Gly Pro Pro Ile Leu Cys Phe Arg Ser Met Asp Arg Arg Ile Glu Asn 
65                  70                  75                  80  


Arg Met Gly Thr Pro Ala His Arg Arg Arg Val Val His Thr His Arg 
                85                  90                  95      


His Thr Arg Asn Arg Leu Ser Cys Pro Trp Pro Pro Pro Phe Thr Ser 
            100                 105                 110         


Pro Thr Leu Thr Pro Gly Ile Leu Leu Gly Thr Ile Thr Leu Ile Thr 
        115                 120                 125             


Glu Leu Cys Glu Arg Ser Pro Ala Ala Leu Arg His Phe Arg Lys Val 
    130                 135                 140                 


Val Pro Gln Leu Val His Ile Leu Arg Thr Leu Val Thr Met Gly Tyr 
145                 150                 155                 160 


Ser Thr Glu His Ser Ile Ser Gly Val Ser Asp Pro Phe Leu Gln Val 
                165                 170                 175     


Gln Ile Leu Arg Leu Leu Arg Ile Leu Gly Arg Asn His Glu Glu Ser 
            180                 185                 190         


Ser Glu Thr Met Asn Asp Leu Leu Ala Gln Val Ala Thr Asn Thr Asp 
        195                 200                 205             


Thr Ser Arg Asn Ala Gly Asn Ala Val Leu Phe Glu Thr Val Leu Thr 
    210                 215                 220                 


Ile Met Asp Ile Arg Ser Ala Ala Gly Leu Arg Val Leu Ala Val Asn 
225                 230                 235                 240 


Ile Leu Gly Arg Phe Leu Leu Asn Ser Asp Arg Asn Ile Arg Tyr Val 
                245                 250                 255     


Ala Leu Thr Ser Leu Leu Arg Leu Val Gln Ser Asp His Ser Ala Val 
            260                 265                 270         


Gln Arg His Arg Pro Thr Val Val Glu Cys Leu Arg Glu Thr Asp Ala 
        275                 280                 285             


Ser Leu Ser Arg Arg Ala Leu Glu Leu Ser Leu Ala Leu Val Asn Ser 
    290                 295                 300                 


Ser Asn Val Arg Ala Met Met Gln Glu Leu Gln Ala Phe Leu Glu Ser 
305                 310                 315                 320 


Cys Pro Pro Asp Leu Arg Ala Asp Cys Ala Ser Gly Ile Leu Leu Ala 
                325                 330                 335     


Ala Glu Arg Phe Ala Pro Thr Lys Arg Trp His Ile Asp Thr Ile Leu 
            340                 345                 350         


His Val Leu Thr Thr Ala Gly Thr His Val Arg Asp Asp Ala Val Ala 
        355                 360                 365             


Asn Leu Thr Gln Leu Ile Gly Gly Ala Gln Glu Leu His Ala Tyr Ser 
    370                 375                 380                 


Val Arg Arg Leu Tyr Asn Ala Leu Ala Glu Asp Ile Ser Gln Gln Pro 
385                 390                 395                 400 


Leu Val Gln Val Ala Ala Trp Cys Ile Gly Glu Tyr Gly Asp Leu Leu 
                405                 410                 415     


Leu Ala Gly Asn Cys Glu Glu Ile Glu Pro Leu Gln Val Asp Glu Glu 
            420                 425                 430         


Glu Val Leu Ala Leu Leu Glu Lys Val Leu Gln Ser His Met Ser Leu 
        435                 440                 445             


Pro Ala Thr Arg Gly Tyr Ala Leu Thr Ala Leu Met Lys Leu Ser Thr 
    450                 455                 460                 


Arg Leu Cys Gly Asp Asn Asn Arg Ile Arg Gln Val Val Ser Ile Tyr 
465                 470                 475                 480 


Gly Ser Cys Leu Asp Val Glu Leu Gln Gln Arg Ala Val Glu Tyr Asp 
                485                 490                 495     


Thr Leu Phe Arg Lys Tyr Asp His Met Arg Ala Ala Ile Leu Glu Lys 
            500                 505                 510         


Met Pro Leu Val Glu Arg Asp Gly Pro Gln Ala Asp Glu Glu Ala Lys 
        515                 520                 525             


Glu Ser Lys Glu Ala Ala Gln Leu Ser Glu Ala Ala Pro Val Pro Thr 
    530                 535                 540                 


Glu Pro Gln Ala Ser Gln Leu Leu Asp Leu Leu Asp Leu Leu Asp Gly 
545                 550                 555                 560 


Ala Ser Gly Asp Val Gln His Pro Pro His Leu Asp Pro Ser Pro Gly 
                565                 570                 575     


Gly Ala Leu Val His Leu Leu Asp Leu Pro Cys Val Pro Pro Pro Pro 
            580                 585                 590         


Ala Pro Ile Pro Asp Leu Lys Val Phe Glu Arg Glu Gly Val Gln Leu 
        595                 600                 605             


Asn Leu Ser Phe Ile Arg Pro Pro Glu Asn Pro Ala Leu Leu Leu Ile 
    610                 615                 620                 


Thr Ile Thr Ala Thr Asn Phe Ser Glu Gly Asp Val Thr His Phe Ile 
625                 630                 635                 640 


Cys Gln Ala Ala Val Pro Lys Ser Leu Gln Leu Gln Leu Gln Ala Pro 
                645                 650                 655     


Ser Gly Asn Thr Val Pro Ala Arg Gly Gly Leu Pro Ile Thr Gln Leu 
            660                 665                 670         


Phe Arg Ile Leu Asn Pro Asn Lys Ala Pro Leu Arg Leu Lys Leu Arg 
        675                 680                 685             


Leu Thr Tyr Asp His Phe His Gln Ser Val Gln Glu Ile Phe Glu Val 
    690                 695                 700                 


Asn Asn Leu Pro Val Glu Ser Trp Gln 
705                 710             


<210>  1463
<211>  2303
<212>  PRT
<213>  Homo sapiens

<400>  1463

Met Ala Ser Ser Val Ala Pro Tyr Glu Gln Leu Val Arg Gln Val Glu 
1               5                   10                  15      


Ala Leu Lys Ala Glu Asn Ser His Leu Arg Gln Glu Leu Arg Asp Asn 
            20                  25                  30          


Ser Ser His Leu Ser Lys Leu Glu Thr Glu Thr Ser Gly Met Lys Glu 
        35                  40                  45              


Val Leu Lys His Leu Gln Gly Lys Leu Glu Gln Glu Ala Arg Val Leu 
    50                  55                  60                  


Val Ser Ser Gly Gln Thr Glu Val Leu Glu Gln Leu Lys Ala Leu Gln 
65                  70                  75                  80  


Met Asp Ile Thr Ser Leu Tyr Asn Leu Lys Phe Gln Pro Pro Thr Leu 
                85                  90                  95      


Gly Pro Glu Pro Ala Ala Arg Thr Pro Glu Gly Ser Pro Val His Gly 
            100                 105                 110         


Ser Gly Pro Ser Lys Asp Ser Phe Gly Glu Leu Ser Arg Ala Thr Ile 
        115                 120                 125             


Arg Leu Leu Glu Glu Leu Asp Arg Glu Arg Cys Phe Leu Leu Asn Glu 
    130                 135                 140                 


Ile Glu Lys Glu Glu Lys Glu Lys Leu Trp Tyr Tyr Ser Gln Leu Gln 
145                 150                 155                 160 


Gly Leu Ser Lys Arg Leu Asp Glu Leu Pro His Val Glu Thr Gln Phe 
                165                 170                 175     


Ser Met Gln Met Asp Leu Ile Arg Gln Gln Leu Glu Phe Glu Ala Gln 
            180                 185                 190         


His Ile Arg Ser Leu Met Glu Glu Arg Phe Gly Thr Ser Asp Glu Met 
        195                 200                 205             


Val Gln Arg Ala Gln Ile Arg Ala Ser Arg Leu Glu Gln Ile Asp Lys 
    210                 215                 220                 


Glu Leu Leu Glu Ala Gln Asp Arg Val Gln Gln Thr Glu Pro Gln Ala 
225                 230                 235                 240 


Leu Leu Ala Val Lys Ser Val Pro Val Asp Glu Asp Pro Glu Thr Glu 
                245                 250                 255     


Val Pro Thr His Pro Glu Asp Gly Thr Pro Gln Pro Gly Asn Ser Lys 
            260                 265                 270         


Val Glu Val Val Phe Trp Leu Leu Ser Met Leu Ala Thr Arg Asp Gln 
        275                 280                 285             


Glu Asp Thr Ala Arg Thr Leu Leu Ala Met Ser Ser Ser Pro Glu Ser 
    290                 295                 300                 


Cys Val Ala Met Arg Arg Ser Gly Cys Leu Pro Leu Leu Leu Gln Ile 
305                 310                 315                 320 


Leu His Gly Thr Glu Ala Ala Ala Gly Gly Arg Ala Gly Ala Pro Gly 
                325                 330                 335     


Ala Pro Gly Ala Lys Asp Ala Arg Met Arg Ala Asn Ala Ala Leu His 
            340                 345                 350         


Asn Ile Val Phe Ser Gln Pro Asp Gln Gly Leu Ala Arg Lys Glu Met 
        355                 360                 365             


Arg Val Leu His Val Leu Glu Gln Ile Arg Ala Tyr Cys Glu Thr Cys 
    370                 375                 380                 


Trp Asp Trp Leu Gln Ala Arg Asp Gly Gly Pro Glu Gly Gly Gly Ala 
385                 390                 395                 400 


Gly Ser Ala Pro Ile Pro Ile Glu Pro Gln Ile Cys Gln Ala Thr Cys 
                405                 410                 415     


Ala Val Met Lys Leu Ser Phe Asp Glu Glu Tyr Arg Arg Ala Met Asn 
            420                 425                 430         


Glu Leu Gly Gly Leu Gln Ala Val Ala Glu Leu Leu Gln Val Asp Tyr 
        435                 440                 445             


Glu Met His Lys Met Thr Arg Asp Pro Leu Asn Leu Ala Leu Arg Arg 
    450                 455                 460                 


Tyr Ala Gly Met Thr Leu Thr Asn Leu Thr Phe Gly Asp Val Ala Asn 
465                 470                 475                 480 


Lys Ala Thr Leu Cys Ala Arg Arg Gly Cys Met Glu Ala Ile Val Ala 
                485                 490                 495     


Gln Leu Ala Ser Asp Ser Glu Glu Leu His Gln Val Val Ser Ser Ile 
            500                 505                 510         


Leu Arg Asn Leu Ser Trp Arg Ala Asp Ile Asn Ser Lys Lys Val Leu 
        515                 520                 525             


Arg Glu Ala Gly Ser Val Thr Ala Leu Val Gln Cys Val Leu Arg Ala 
    530                 535                 540                 


Thr Lys Glu Ser Thr Leu Lys Ser Val Leu Ser Ala Leu Trp Asn Leu 
545                 550                 555                 560 


Ser Ala His Ser Thr Glu Asn Lys Ala Ala Ile Cys Gln Val Asp Gly 
                565                 570                 575     


Ala Leu Gly Phe Leu Val Ser Thr Leu Thr Tyr Lys Cys Gln Ser Asn 
            580                 585                 590         


Ser Leu Ala Ile Ile Glu Ser Gly Gly Gly Ile Leu Arg Asn Val Ser 
        595                 600                 605             


Ser Leu Val Ala Thr Arg Glu Asp Tyr Arg Gln Val Leu Arg Asp His 
    610                 615                 620                 


Asn Cys Leu Gln Thr Leu Leu Gln His Leu Thr Ser His Ser Leu Thr 
625                 630                 635                 640 


Ile Val Ser Asn Ala Cys Gly Thr Leu Trp Asn Leu Ser Ala Arg Ser 
                645                 650                 655     


Ala Arg Asp Gln Glu Leu Leu Trp Asp Leu Gly Ala Val Gly Met Leu 
            660                 665                 670         


Arg Asn Leu Val His Ser Lys His Lys Met Ile Ala Met Gly Ser Ala 
        675                 680                 685             


Ala Ala Leu Arg Asn Leu Leu Ala His Arg Pro Ala Lys His Gln Ala 
    690                 695                 700                 


Ala Ala Thr Ala Val Ser Pro Gly Ser Cys Val Pro Ser Leu Tyr Val 
705                 710                 715                 720 


Arg Lys Gln Arg Ala Leu Glu Ala Glu Leu Asp Ala Arg His Leu Ala 
                725                 730                 735     


Gln Ala Leu Glu His Leu Glu Lys Gln Gly Pro Pro Ala Ala Glu Ala 
            740                 745                 750         


Ala Thr Lys Lys Pro Leu Pro Pro Leu Arg His Leu Asp Gly Leu Ala 
        755                 760                 765             


Gln Asp Tyr Ala Ser Asp Ser Gly Cys Phe Asp Asp Asp Asp Ala Pro 
    770                 775                 780                 


Ser Ser Leu Ala Ala Ala Ala Ala Thr Gly Glu Pro Ala Ser Pro Ala 
785                 790                 795                 800 


Ala Leu Ser Leu Phe Leu Gly Ser Pro Phe Leu Gln Gly Gln Ala Leu 
                805                 810                 815     


Ala Arg Thr Pro Pro Thr Arg Arg Gly Gly Lys Glu Ala Glu Lys Asp 
            820                 825                 830         


Thr Ser Gly Glu Ala Ala Val Ala Ala Lys Ala Lys Ala Lys Leu Ala 
        835                 840                 845             


Leu Ala Val Ala Arg Ile Asp Gln Leu Val Glu Asp Ile Ser Ala Leu 
    850                 855                 860                 


His Thr Ser Ser Asp Asp Ser Phe Ser Leu Ser Ser Gly Asp Pro Gly 
865                 870                 875                 880 


Gln Glu Ala Pro Arg Glu Gly Arg Ala Gln Ser Cys Ser Pro Cys Arg 
                885                 890                 895     


Gly Pro Glu Gly Gly Arg Arg Glu Ala Gly Ser Arg Ala His Pro Leu 
            900                 905                 910         


Leu Arg Leu Lys Ala Ala His Ala Ser Leu Ser Asn Asp Ser Leu Asn 
        915                 920                 925             


Ser Gly Ser Ala Ser Asp Gly Tyr Cys Pro Arg Glu His Met Leu Pro 
    930                 935                 940                 


Cys Pro Leu Ala Ala Leu Ala Ser Arg Arg Glu Asp Pro Arg Cys Gly 
945                 950                 955                 960 


Gln Pro Arg Pro Ser Arg Leu Asp Leu Asp Leu Pro Gly Cys Gln Ala 
                965                 970                 975     


Glu Pro Pro Ala Arg Glu Ala Thr Ser Ala Asp Ala Arg Val Arg Thr 
            980                 985                 990         


Ile Lys Leu Ser Pro Thr Tyr Gln  His Val Pro Leu Leu  Glu Gly Ala 
        995                 1000                 1005             


Ser Arg  Ala Gly Ala Glu Pro  Leu Ala Gly Pro Gly  Ile Ser Pro 
    1010                 1015                 1020             


Gly Ala  Arg Lys Gln Ala Trp  Leu Pro Ala Asp His  Leu Ser Lys 
    1025                 1030                 1035             


Val Pro  Glu Lys Leu Ala Ala  Ala Pro Leu Ser Val  Ala Ser Lys 
    1040                 1045                 1050             


Ala Leu  Gln Lys Leu Ala Ala  Gln Glu Gly Pro Leu  Ser Leu Ser 
    1055                 1060                 1065             


Arg Cys  Ser Ser Leu Ser Ser  Leu Ser Ser Ala Gly  Arg Pro Gly 
    1070                 1075                 1080             


Pro Ser  Glu Gly Gly Asp Leu  Asp Asp Ser Asp Ser  Ser Leu Glu 
    1085                 1090                 1095             


Gly Leu  Glu Glu Ala Gly Pro  Ser Glu Ala Glu Leu  Asp Ser Thr 
    1100                 1105                 1110             


Trp Arg  Ala Pro Gly Ala Thr  Ser Leu Pro Val Ala  Ile Pro Ala 
    1115                 1120                 1125             


Pro Arg  Arg Asn Arg Gly Arg  Gly Leu Gly Val Glu  Asp Ala Thr 
    1130                 1135                 1140             


Pro Ser  Ser Ser Ser Glu Asn  Tyr Val Gln Glu Thr  Pro Leu Val 
    1145                 1150                 1155             


Leu Ser  Arg Cys Ser Ser Val  Ser Ser Leu Gly Ser  Phe Glu Ser 
    1160                 1165                 1170             


Pro Ser  Ile Ala Ser Ser Ile  Pro Ser Glu Pro Cys  Ser Gly Gln 
    1175                 1180                 1185             


Gly Ser  Gly Thr Ile Ser Pro  Ser Glu Leu Pro Asp  Ser Pro Gly 
    1190                 1195                 1200             


Gln Thr  Met Pro Pro Ser Arg  Ser Lys Thr Pro Pro  Leu Ala Pro 
    1205                 1210                 1215             


Ala Pro  Gln Gly Pro Pro Glu  Ala Thr Gln Phe Ser  Leu Gln Trp 
    1220                 1225                 1230             


Glu Ser  Tyr Val Lys Arg Phe  Leu Asp Ile Ala Asp  Cys Arg Glu 
    1235                 1240                 1245             


Arg Cys  Arg Leu Pro Ser Glu  Leu Asp Ala Gly Ser  Val Arg Phe 
    1250                 1255                 1260             


Thr Val  Glu Lys Pro Asp Glu  Asn Phe Ser Cys Ala  Ser Ser Leu 
    1265                 1270                 1275             


Ser Ala  Leu Ala Leu His Glu  His Tyr Val Gln Gln  Asp Val Glu 
    1280                 1285                 1290             


Leu Arg  Leu Leu Pro Ser Ala  Cys Pro Glu Arg Gly  Gly Gly Ala 
    1295                 1300                 1305             


Gly Gly  Ala Gly Leu His Phe  Ala Gly His Arg Arg  Arg Glu Glu 
    1310                 1315                 1320             


Gly Pro  Ala Pro Thr Gly Ser  Arg Pro Arg Gly Ala  Ala Asp Gln 
    1325                 1330                 1335             


Glu Leu  Glu Leu Leu Arg Glu  Cys Leu Gly Ala Ala  Val Pro Ala 
    1340                 1345                 1350             


Arg Leu  Arg Lys Val Ala Ser  Ala Leu Val Pro Gly  Arg Arg Ala 
    1355                 1360                 1365             


Leu Pro  Val Pro Val Tyr Met  Leu Val Pro Ala Pro  Ala Pro Ala 
    1370                 1375                 1380             


Gln Glu  Asp Asp Ser Cys Thr  Asp Ser Ala Glu Gly  Thr Pro Val 
    1385                 1390                 1395             


Asn Phe  Ser Ser Ala Ala Ser  Leu Ser Asp Glu Thr  Leu Gln Gly 
    1400                 1405                 1410             


Pro Pro  Arg Asp Gln Pro Gly  Gly Pro Ala Gly Arg  Gln Arg Pro 
    1415                 1420                 1425             


Thr Gly  Arg Pro Thr Ser Ala  Arg Gln Ala Met Gly  His Arg His 
    1430                 1435                 1440             


Lys Ala  Gly Gly Ala Gly Arg  Ser Ala Glu Gln Ser  Arg Gly Ala 
    1445                 1450                 1455             


Gly Lys  Asn Arg Ala Gly Leu  Glu Leu Pro Leu Gly  Arg Pro Pro 
    1460                 1465                 1470             


Ser Ala  Pro Ala Asp Lys Asp  Gly Ser Lys Pro Gly  Arg Thr Arg 
    1475                 1480                 1485             


Gly Asp  Gly Ala Leu Gln Ser  Leu Cys Leu Thr Thr  Pro Thr Glu 
    1490                 1495                 1500             


Glu Ala  Val Tyr Cys Phe Tyr  Gly Asn Asp Ser Asp  Glu Glu Pro 
    1505                 1510                 1515             


Pro Ala  Ala Ala Pro Thr Pro  Thr His Arg Arg Thr  Ser Ala Ile 
    1520                 1525                 1530             


Pro Arg  Ala Phe Thr Arg Glu  Arg Pro Gln Gly Arg  Lys Glu Ala 
    1535                 1540                 1545             


Pro Ala  Pro Ser Lys Ala Ala  Pro Ala Ala Pro Pro  Pro Ala Arg 
    1550                 1555                 1560             


Thr Gln  Pro Ser Leu Ile Ala  Asp Glu Thr Pro Pro  Cys Tyr Ser 
    1565                 1570                 1575             


Leu Ser  Ser Ser Ala Ser Ser  Leu Ser Glu Pro Glu  Pro Ser Glu 
    1580                 1585                 1590             


Pro Pro  Ala Val His Pro Arg  Gly Arg Glu Pro Ala  Val Thr Lys 
    1595                 1600                 1605             


Asp Pro  Gly Pro Gly Gly Gly  Arg Asp Ser Ser Pro  Ser Pro Arg 
    1610                 1615                 1620             


Ala Ala  Glu Glu Leu Leu Gln  Arg Cys Ile Ser Ser  Ala Leu Pro 
    1625                 1630                 1635             


Arg Arg  Arg Pro Pro Val Ser  Gly Leu Arg Arg Arg  Lys Pro Arg 
    1640                 1645                 1650             


Ala Thr  Arg Leu Asp Glu Arg  Pro Ala Glu Gly Ser  Arg Glu Arg 
    1655                 1660                 1665             


Gly Glu  Glu Ala Ala Gly Ser  Asp Arg Ala Ser Asp  Leu Asp Ser 
    1670                 1675                 1680             


Val Glu  Trp Arg Ala Ile Gln  Glu Gly Ala Asn Ser  Ile Val Thr 
    1685                 1690                 1695             


Trp Leu  His Gln Ala Ala Ala  Ala Thr Arg Glu Ala  Ser Ser Glu 
    1700                 1705                 1710             


Ser Asp  Ser Ile Leu Ser Phe  Val Ser Gly Leu Ser  Val Gly Ser 
    1715                 1720                 1725             


Thr Leu  Gln Pro Pro Lys His  Arg Lys Gly Arg Gln  Ala Glu Gly 
    1730                 1735                 1740             


Glu Met  Gly Ser Ala Arg Arg  Pro Glu Lys Arg Gly  Ala Ala Ser 
    1745                 1750                 1755             


Val Lys  Thr Ser Gly Ser Pro  Arg Ser Pro Ala Gly  Pro Glu Lys 
    1760                 1765                 1770             


Pro Arg  Gly Thr Gln Lys Thr  Thr Pro Gly Val Pro  Ala Val Leu 
    1775                 1780                 1785             


Arg Gly  Arg Thr Val Ile Tyr  Val Pro Ser Pro Ala  Pro Arg Ala 
    1790                 1795                 1800             


Gln Pro  Lys Gly Thr Pro Gly  Pro Arg Ala Thr Pro  Arg Lys Val 
    1805                 1810                 1815             


Ala Pro  Pro Cys Leu Ala Gln  Pro Ala Ala Pro Ala  Lys Val Pro 
    1820                 1825                 1830             


Ser Pro  Gly Gln Gln Arg Ser  Arg Ser Leu His Arg  Pro Ala Lys 
    1835                 1840                 1845             


Thr Ser  Glu Leu Ala Thr Leu  Ser Gln Pro Pro Arg  Ser Ala Thr 
    1850                 1855                 1860             


Pro Pro  Ala Arg Leu Ala Lys  Thr Pro Ser Ser Ser  Ser Ser Gln 
    1865                 1870                 1875             


Thr Ser  Pro Ala Ser Gln Pro  Leu Pro Arg Lys Arg  Pro Pro Val 
    1880                 1885                 1890             


Thr Gln  Ala Ala Gly Ala Leu  Pro Gly Pro Gly Ala  Ser Pro Val 
    1895                 1900                 1905             


Pro Lys  Thr Pro Ala Arg Thr  Leu Leu Ala Lys Gln  His Lys Thr 
    1910                 1915                 1920             


Gln Arg  Ser Pro Val Arg Ile  Pro Phe Met Gln Arg  Pro Ala Arg 
    1925                 1930                 1935             


Arg Gly  Pro Pro Pro Leu Ala  Arg Ala Val Pro Glu  Pro Gly Pro 
    1940                 1945                 1950             


Arg Gly  Arg Ala Gly Thr Glu  Ala Gly Pro Gly Ala  Arg Gly Gly 
    1955                 1960                 1965             


Arg Leu  Gly Leu Val Arg Val  Ala Ser Ala Leu Ser  Ser Gly Ser 
    1970                 1975                 1980             


Glu Ser  Ser Asp Arg Ser Gly  Phe Arg Arg Gln Leu  Thr Phe Ile 
    1985                 1990                 1995             


Lys Glu  Ser Pro Gly Leu Arg  Arg Arg Arg Ser Glu  Leu Ser Ser 
    2000                 2005                 2010             


Ala Glu  Ser Ala Ala Ser Ala  Pro Gln Gly Ala Ser  Pro Arg Arg 
    2015                 2020                 2025             


Gly Arg  Pro Ala Leu Pro Ala  Val Phe Leu Cys Ser  Ser Arg Cys 
    2030                 2035                 2040             


Glu Glu  Leu Arg Ala Ala Pro  Arg Gln Gly Pro Ala  Pro Ala Arg 
    2045                 2050                 2055             


Gln Arg  Pro Pro Ala Ala Arg  Pro Ser Pro Gly Glu  Arg Pro Ala 
    2060                 2065                 2070             


Arg Arg  Thr Thr Ser Glu Ser  Pro Ser Arg Leu Pro  Val Arg Ala 
    2075                 2080                 2085             


Pro Ala  Ala Arg Pro Glu Thr  Val Lys Arg Tyr Ala  Ser Leu Pro 
    2090                 2095                 2100             


His Ile  Ser Val Ala Arg Arg  Pro Asp Gly Ala Val  Pro Ala Ala 
    2105                 2110                 2115             


Pro Ala  Ser Ala Asp Ala Ala  Arg Arg Ser Ser Asp  Gly Glu Pro 
    2120                 2125                 2130             


Arg Pro  Leu Pro Arg Val Ala  Ala Pro Gly Thr Thr  Trp Arg Arg 
    2135                 2140                 2145             


Ile Arg  Asp Glu Asp Val Pro  His Ile Leu Arg Ser  Thr Leu Pro 
    2150                 2155                 2160             


Ala Thr  Ala Leu Pro Leu Arg  Gly Ser Thr Pro Glu  Asp Ala Pro 
    2165                 2170                 2175             


Ala Gly  Pro Pro Pro Arg Lys  Thr Ser Asp Ala Val  Val Gln Thr 
    2180                 2185                 2190             


Glu Glu  Val Ala Ala Pro Lys  Thr Asn Ser Ser Thr  Ser Pro Ser 
    2195                 2200                 2205             


Leu Glu  Thr Arg Glu Pro Pro  Gly Ala Pro Ala Gly  Gly Gln Leu 
    2210                 2215                 2220             


Ser Leu  Leu Gly Ser Asp Val  Asp Gly Pro Ser Leu  Ala Lys Ala 
    2225                 2230                 2235             


Pro Ile  Ser Ala Pro Phe Val  His Glu Gly Leu Gly  Val Ala Val 
    2240                 2245                 2250             


Gly Gly  Phe Pro Ala Ser Arg  His Gly Ser Pro Ser  Arg Ser Ala 
    2255                 2260                 2265             


Arg Val  Pro Pro Phe Asn Tyr  Val Pro Ser Pro Met  Val Val Ala 
    2270                 2275                 2280             


Ala Thr  Thr Asp Ser Ala Ala  Glu Lys Ala Pro Ala  Thr Ala Ser 
    2285                 2290                 2295             


Ala Thr  Leu Leu Glu 
    2300             


<210>  1464
<211>  541
<212>  PRT
<213>  Homo sapiens

<400>  1464

Met Ser Gln Leu Val Glu Cys Val Pro Asn Phe Ser Glu Gly Lys Asn 
1               5                   10                  15      


Gln Glu Val Ile Asp Ala Ile Ser Gly Ala Ile Thr Gln Thr Pro Gly 
            20                  25                  30          


Cys Val Leu Leu Asp Val Asp Ala Gly Pro Ser Thr Asn Arg Thr Val 
        35                  40                  45              


Tyr Thr Phe Val Gly Pro Pro Glu Cys Val Val Glu Gly Ala Leu Asn 
    50                  55                  60                  


Ala Ala Arg Val Ala Ser Arg Leu Ile Asp Met Ser Arg His Gln Gly 
65                  70                  75                  80  


Glu His Pro Arg Met Gly Ala Leu Asp Val Cys Pro Phe Ile Pro Val 
                85                  90                  95      


Arg Gly Val Ser Val Asp Glu Cys Val Leu Cys Ala Gln Ala Phe Gly 
            100                 105                 110         


Gln Arg Leu Ala Glu Glu Leu Asp Val Pro Val Tyr Leu Tyr Gly Glu 
        115                 120                 125             


Ala Ala Arg Met Asp Ser Arg Arg Thr Leu Pro Ala Ile Arg Ala Gly 
    130                 135                 140                 


Glu Tyr Glu Ala Leu Pro Lys Lys Leu Gln Gln Ala Asp Trp Ala Pro 
145                 150                 155                 160 


Asp Phe Gly Pro Ser Ser Phe Val Pro Ser Trp Gly Ala Thr Ala Thr 
                165                 170                 175     


Gly Ala Arg Lys Phe Leu Ile Ala Phe Asn Ile Asn Leu Leu Gly Thr 
            180                 185                 190         


Lys Glu Gln Ala His Arg Ile Ala Leu Asn Leu Arg Glu Gln Gly Arg 
        195                 200                 205             


Gly Lys Asp Gln Pro Gly Arg Leu Lys Lys Val Gln Gly Ile Gly Trp 
    210                 215                 220                 


Tyr Leu Asp Glu Lys Asn Leu Ala Gln Val Ser Thr Asn Leu Leu Asp 
225                 230                 235                 240 


Phe Glu Val Thr Ala Leu His Thr Val Tyr Glu Glu Thr Cys Arg Glu 
                245                 250                 255     


Ala Gln Glu Leu Ser Leu Pro Val Val Gly Ser Gln Leu Val Gly Leu 
            260                 265                 270         


Val Pro Leu Lys Ala Leu Leu Asp Ala Ala Ala Phe Tyr Cys Glu Lys 
        275                 280                 285             


Glu Asn Leu Phe Ile Leu Glu Glu Glu Gln Arg Ile Arg Leu Val Val 
    290                 295                 300                 


Ser Arg Leu Gly Leu Asp Ser Leu Cys Pro Phe Ser Pro Lys Glu Arg 
305                 310                 315                 320 


Ile Ile Glu Tyr Leu Val Pro Glu Arg Gly Pro Glu Arg Gly Leu Gly 
                325                 330                 335     


Ser Lys Ser Leu Arg Ala Phe Val Gly Glu Val Gly Ala Arg Ser Ala 
            340                 345                 350         


Ala Pro Gly Gly Gly Ser Val Ala Ala Ala Ala Ala Ala Met Gly Ala 
        355                 360                 365             


Ala Leu Gly Ser Met Val Gly Leu Met Thr Tyr Gly Arg Arg Gln Phe 
    370                 375                 380                 


Gln Ser Leu Asp Thr Thr Met Arg Arg Leu Ile Pro Pro Phe Arg Glu 
385                 390                 395                 400 


Ala Ser Ala Lys Leu Thr Thr Leu Val Asp Ala Asp Ala Glu Ala Phe 
                405                 410                 415     


Thr Ala Tyr Leu Glu Ala Met Arg Leu Pro Lys Asn Thr Pro Glu Glu 
            420                 425                 430         


Lys Asp Arg Arg Thr Ala Ala Leu Gln Glu Gly Leu Arg Arg Ala Val 
        435                 440                 445             


Ser Val Pro Leu Thr Leu Ala Glu Thr Val Ala Ser Leu Trp Pro Ala 
    450                 455                 460                 


Leu Gln Glu Leu Ala Arg Cys Gly Asn Leu Ala Cys Arg Ser Asp Leu 
465                 470                 475                 480 


Gln Val Ala Ala Lys Ala Leu Glu Met Gly Val Phe Gly Ala Tyr Phe 
                485                 490                 495     


Asn Val Leu Ile Asn Leu Arg Asp Ile Thr Asp Glu Ala Phe Lys Asp 
            500                 505                 510         


Gln Ile His His Arg Val Ser Ser Leu Leu Gln Glu Ala Lys Thr Gln 
        515                 520                 525             


Ala Ala Leu Val Leu Asp Cys Leu Glu Thr Arg Gln Glu 
    530                 535                 540     


<210>  1465
<211>  246
<212>  PRT
<213>  Homo sapiens

<400>  1465

Met Asn Asp Trp Met Pro Ile Ala Lys Glu Tyr Asp Pro Leu Lys Ala 
1               5                   10                  15      


Gly Ser Ile Asp Gly Thr Asp Glu Asp Pro His Asp Arg Ala Val Trp 
            20                  25                  30          


Arg Ala Met Leu Ala Arg Tyr Val Pro Asn Lys Gly Val Ile Gly Asp 
        35                  40                  45              


Pro Leu Leu Thr Leu Phe Val Ala Arg Leu Asn Leu Gln Thr Lys Glu 
    50                  55                  60                  


Asp Lys Leu Lys Glu Val Phe Ser Arg Tyr Gly Asp Ile Arg Arg Leu 
65                  70                  75                  80  


Arg Leu Val Arg Asp Leu Val Thr Gly Phe Ser Lys Gly Tyr Ala Phe 
                85                  90                  95      


Ile Glu Tyr Lys Glu Glu Arg Ala Val Ile Lys Ala Tyr Arg Asp Ala 
            100                 105                 110         


Asp Gly Leu Val Ile Asp Gln His Glu Ile Phe Val Asp Tyr Glu Leu 
        115                 120                 125             


Glu Arg Thr Leu Lys Gly Trp Ile Pro Arg Arg Leu Gly Gly Gly Leu 
    130                 135                 140                 


Gly Gly Lys Lys Glu Ser Gly Gln Leu Arg Phe Gly Gly Arg Asp Arg 
145                 150                 155                 160 


Pro Phe Arg Lys Pro Ile Asn Leu Pro Val Val Lys Asn Asp Leu Tyr 
                165                 170                 175     


Arg Glu Gly Lys Arg Glu Arg Arg Glu Arg Ser Arg Ser Arg Glu Arg 
            180                 185                 190         


His Trp Asp Ser Arg Thr Arg Asp Arg Asp His Asp Arg Gly Arg Glu 
        195                 200                 205             


Lys Arg Trp Gln Glu Arg Glu Pro Thr Arg Val Trp Pro Asp Asn Asp 
    210                 215                 220                 


Trp Glu Arg Glu Arg Asp Phe Arg Asp Asp Arg Ile Lys Gly Arg Glu 
225                 230                 235                 240 


Lys Lys Glu Arg Gly Lys 
                245     


<210>  1466
<211>  117
<212>  PRT
<213>  Homo sapiens

<400>  1466

Met Lys Trp Met Phe Lys Glu Asp His Ser Leu Glu His Arg Cys Val 
1               5                   10                  15      


Glu Ser Ala Lys Ile Arg Ala Lys Tyr Pro Asp Arg Val Pro Val Ile 
            20                  25                  30          


Val Glu Lys Val Ser Gly Ser Gln Ile Val Asp Ile Asp Lys Arg Lys 
        35                  40                  45              


Tyr Leu Val Pro Ser Asp Ile Thr Val Ala Gln Phe Met Trp Ile Ile 
    50                  55                  60                  


Arg Lys Arg Ile Gln Leu Pro Ser Glu Lys Ala Ile Phe Leu Phe Val 
65                  70                  75                  80  


Asp Lys Thr Val Pro Gln Ser Ser Leu Thr Met Gly Gln Leu Tyr Glu 
                85                  90                  95      


Lys Glu Lys Asp Glu Asp Gly Phe Leu Tyr Val Ala Tyr Ser Gly Glu 
            100                 105                 110         


Asn Thr Phe Gly Phe 
        115         


<210>  1467
<211>  482
<212>  PRT
<213>  Homo sapiens

<400>  1467

Met Leu Phe Glu Gly Lys Val Asn Pro Gln Thr Gln Ser Leu Leu Ala 
1               5                   10                  15      


Glu Cys Gly Glu Trp Thr Arg Arg Ser Leu His Leu Arg Val Leu Gly 
            20                  25                  30          


Arg Gln Leu Ile Leu Pro Thr Asp Lys Gly Val Gln His Phe Gln Gly 
        35                  40                  45              


Ser Thr Pro Ala Ser Ala Val His Arg Pro Pro Leu Ser Ala Cys Gly 
    50                  55                  60                  


His Ser Ser Asn Ile Arg Glu Leu Cys Ile Ser Gly Ser Gln Ile Val 
65                  70                  75                  80  


Pro Ala Ala Leu Ser Ala Ser Ala Leu Pro Gly Pro Asp Asp Thr Gly 
                85                  90                  95      


Val Ala Asp Leu Thr Ala Arg Ser Ser Leu Glu Glu Glu Val Tyr His 
            100                 105                 110         


Val Asp Gly Lys Ile Glu Glu Tyr Phe Ala Phe Asp Arg Lys Glu Asp 
        115                 120                 125             


Asp Asp Glu Cys Leu Glu Gln Lys Pro Ala Gln Pro Gly Arg Lys Trp 
    130                 135                 140                 


Arg Lys Leu Gly Leu Pro Pro Val Ser Pro Arg Asp Cys Val Lys Asp 
145                 150                 155                 160 


Ala Val Ala Ala Glu Val Phe Asp His Val Trp Thr Asn Met Val Glu 
                165                 170                 175     


Leu Leu Glu Glu Leu Ile Arg Lys His Trp Glu Thr Thr Leu Thr Glu 
            180                 185                 190         


Gly Lys Lys Gln Arg Glu Thr Leu Lys Val Ala Gly Asn Arg Phe Pro 
        195                 200                 205             


His Val Leu Val Pro His Ala His Ala Asp Gly Ala Ser Gly Pro Pro 
    210                 215                 220                 


Ser Gly His Ala Glu Ala His Gly Ile Ser Leu Ala Ser Arg Leu Asn 
225                 230                 235                 240 


Pro Pro Gln Ile His His Phe Ser Ser Ser Phe Tyr Ser Asp Met Asn 
                245                 250                 255     


Gly Val Met Thr Ile Gln Ala Lys Pro Leu Gln Arg Arg Pro Ala Tyr 
            260                 265                 270         


Phe Ala Asp Arg Thr Gln Asn Glu Lys Glu Asp Lys Ala Ser Gly Gly 
        275                 280                 285             


Gly Ala Gly Ala Leu Ser Ser Ala Pro His Arg Leu Gly Arg Ala Ser 
    290                 295                 300                 


Asp Thr His Gly Leu Ser Pro Ser Ala Lys Lys Thr Pro Val Pro Trp 
305                 310                 315                 320 


Arg Leu Pro Ser Leu Ala Ser Asp Ser Gln Arg Leu Lys Thr Pro Asn 
                325                 330                 335     


Ile Tyr Ser Asp Glu Val Leu Arg Gly Thr Lys Leu Pro Thr Gly Val 
            340                 345                 350         


Asp His Met Ala Ser Pro Leu Val Gln Thr Ser Arg Ser Arg Phe Pro 
        355                 360                 365             


Pro Leu Val Thr Glu Thr Arg Gly Gln Asn Thr Ala Val Pro Gly Cys 
    370                 375                 380                 


Arg Leu Val Ser Tyr Arg Gly Arg His Leu Gln Asn Arg Val Leu Ser 
385                 390                 395                 400 


Ala Met Pro Asp Gly Thr Glu Arg Ser Arg Leu Arg Glu Arg Thr Ala 
                405                 410                 415     


Thr Leu Glu Arg Leu Ser Arg Pro Ser Thr Thr His Thr Phe Arg Gln 
            420                 425                 430         


Ser Asp Thr Pro Arg Lys Ser Ser Leu Thr Gln Met Glu Phe Ala Ala 
        435                 440                 445             


His Thr Trp Thr Gly Gln Ser Ile Leu Thr Gly Ser Gln Tyr Val Pro 
    450                 455                 460                 


Lys Ser Phe Gln Arg Thr Thr Leu Thr Phe Lys Arg Arg Phe Gln Val 
465                 470                 475                 480 


Thr Ser 
        


<210>  1468
<211>  463
<212>  PRT
<213>  Homo sapiens

<400>  1468

Met Ser Gly Gly Thr Pro Tyr Ile Gly Ser Lys Ile Ser Leu Ile Ser 
1               5                   10                  15      


Lys Ala Glu Ile Arg Tyr Glu Gly Ile Leu Tyr Thr Ile Asp Thr Glu 
            20                  25                  30          


Asn Ser Thr Val Ala Leu Ala Lys Val Arg Ser Phe Gly Thr Glu Asp 
        35                  40                  45              


Arg Pro Thr Asp Arg Pro Ile Pro Pro Arg Asp Glu Val Phe Glu Tyr 
    50                  55                  60                  


Ile Ile Phe Arg Gly Ser Asp Ile Lys Asp Leu Thr Val Cys Glu Pro 
65                  70                  75                  80  


Pro Lys Pro Gln Cys Ser Leu Pro Gln Asp Pro Ala Ile Val Gln Ser 
                85                  90                  95      


Ser Leu Gly Ser Ser Thr Ser Ser Phe Gln Ser Met Gly Ser Tyr Gly 
            100                 105                 110         


Pro Phe Gly Arg Met Pro Thr Tyr Ser Gln Phe Ser Pro Ser Ser Leu 
        115                 120                 125             


Val Gly Gln Gln Phe Gly Ala Val Gly Val Ala Gly Ser Ser Leu Thr 
    130                 135                 140                 


Ser Phe Gly Thr Glu Thr Ser Asn Ser Gly Thr Leu Pro Gln Ser Ser 
145                 150                 155                 160 


Ala Val Gly Ser Ala Phe Thr Gln Asp Thr Arg Ser Leu Lys Thr Gln 
                165                 170                 175     


Leu Ser Gln Gly Arg Ser Ser Pro Gln Leu Asp Pro Leu Arg Lys Ser 
            180                 185                 190         


Pro Thr Met Glu Gln Ala Val Gln Thr Ala Ser Ala His Leu Pro Ala 
        195                 200                 205             


Pro Ala Ala Val Gly Arg Arg Ser Pro Val Ser Thr Arg Pro Leu Pro 
    210                 215                 220                 


Ser Ala Ser Gln Lys Ala Gly Glu Asn Gln Glu His Arg Arg Ala Glu 
225                 230                 235                 240 


Val His Lys Val Ser Arg Pro Glu Asn Glu Gln Leu Arg Asn Asp Asn 
                245                 250                 255     


Lys Arg Gln Val Ala Pro Gly Ala Pro Ser Ala Pro Arg Arg Gly Arg 
            260                 265                 270         


Gly Gly His Arg Gly Gly Arg Gly Arg Phe Gly Ile Arg Arg Asp Gly 
        275                 280                 285             


Pro Met Lys Phe Glu Lys Asp Phe Asp Phe Glu Ser Ala Asn Ala Gln 
    290                 295                 300                 


Phe Asn Lys Glu Glu Ile Asp Arg Glu Phe His Asn Lys Leu Lys Leu 
305                 310                 315                 320 


Lys Glu Asp Lys Leu Glu Lys Gln Glu Lys Pro Val Asn Gly Glu Asp 
                325                 330                 335     


Lys Gly Asp Ser Gly Val Asp Thr Gln Asn Ser Glu Gly Asn Ala Asp 
            340                 345                 350         


Glu Glu Asp Pro Leu Gly Pro Asn Cys Tyr Tyr Asp Lys Thr Lys Ser 
        355                 360                 365             


Phe Phe Asp Asn Ile Ser Cys Asp Asp Asn Arg Glu Arg Arg Pro Thr 
    370                 375                 380                 


Trp Ala Glu Glu Arg Arg Leu Asn Ala Glu Thr Phe Gly Ile Pro Leu 
385                 390                 395                 400 


Arg Pro Asn Arg Gly Arg Gly Gly Tyr Arg Gly Arg Gly Gly Leu Gly 
                405                 410                 415     


Phe Arg Gly Gly Arg Gly Arg Gly Gly Gly Arg Gly Gly Thr Phe Thr 
            420                 425                 430         


Ala Pro Arg Gly Phe Arg Gly Gly Phe Arg Gly Gly Arg Gly Gly Arg 
        435                 440                 445             


Glu Phe Ala Asp Phe Glu Tyr Arg Lys Asp Asn Lys Val Ala Ala 
    450                 455                 460             


<210>  1469
<211>  178
<212>  PRT
<213>  Homo sapiens

<400>  1469

Met Ser Ser Phe Ser Arg Ala Pro Gln Gln Trp Ala Thr Phe Ala Arg 
1               5                   10                  15      


Ile Trp Tyr Leu Leu Asp Gly Lys Met Gln Pro Pro Gly Lys Leu Ala 
            20                  25                  30          


Ala Met Ala Ser Ile Arg Leu Gln Gly Leu His Lys Pro Val Tyr His 
        35                  40                  45              


Ala Leu Ser Asp Cys Gly Asp His Val Val Ile Met Asn Thr Arg His 
    50                  55                  60                  


Ile Ala Phe Ser Gly Asn Lys Trp Glu Gln Lys Val Tyr Ser Ser His 
65                  70                  75                  80  


Thr Gly Tyr Pro Gly Gly Phe Arg Gln Val Thr Ala Ala Gln Leu His 
                85                  90                  95      


Leu Arg Asp Pro Val Ala Ile Val Lys Leu Ala Ile Tyr Gly Met Leu 
            100                 105                 110         


Pro Lys Asn Leu His Arg Arg Thr Met Met Glu Arg Leu His Leu Phe 
        115                 120                 125             


Pro Asp Glu Tyr Ile Pro Glu Asp Ile Leu Lys Asn Leu Val Glu Glu 
    130                 135                 140                 


Leu Pro Gln Pro Arg Lys Ile Pro Lys Arg Leu Asp Glu Tyr Thr Gln 
145                 150                 155                 160 


Glu Glu Ile Asp Ala Phe Pro Arg Leu Trp Thr Pro Pro Glu Asp Tyr 
                165                 170                 175     


Arg Leu 
        


<210>  1470
<211>  1176
<212>  PRT
<213>  Homo sapiens

<400>  1470

Met Ala Glu Arg Lys Gly Thr Ala Lys Val Asp Phe Leu Lys Lys Ile 
1               5                   10                  15      


Glu Lys Glu Ile Gln Gln Lys Trp Asp Thr Glu Arg Val Phe Glu Val 
            20                  25                  30          


Asn Ala Ser Asn Leu Glu Lys Gln Thr Ser Lys Gly Lys Tyr Phe Val 
        35                  40                  45              


Thr Phe Pro Tyr Pro Tyr Met Asn Gly Arg Leu His Leu Gly His Thr 
    50                  55                  60                  


Phe Ser Leu Ser Lys Cys Glu Phe Ala Val Gly Tyr Gln Arg Leu Lys 
65                  70                  75                  80  


Gly Lys Cys Cys Leu Phe Pro Phe Gly Leu His Cys Thr Gly Met Pro 
                85                  90                  95      


Ile Lys Ala Cys Ala Asp Lys Leu Lys Arg Glu Ile Glu Leu Tyr Gly 
            100                 105                 110         


Cys Pro Pro Asp Phe Pro Asp Glu Glu Glu Glu Glu Glu Glu Thr Ser 
        115                 120                 125             


Val Lys Thr Glu Asp Ile Ile Ile Lys Asp Lys Ala Lys Gly Lys Lys 
    130                 135                 140                 


Ser Lys Ala Ala Ala Lys Ala Gly Ser Ser Lys Tyr Gln Trp Gly Ile 
145                 150                 155                 160 


Met Lys Ser Leu Gly Leu Ser Asp Glu Glu Ile Val Lys Phe Ser Glu 
                165                 170                 175     


Ala Glu His Trp Leu Asp Tyr Phe Pro Pro Leu Ala Ile Gln Asp Leu 
            180                 185                 190         


Lys Arg Met Gly Leu Lys Val Asp Trp Arg Arg Ser Phe Ile Thr Thr 
        195                 200                 205             


Asp Val Asn Pro Tyr Tyr Asp Ser Phe Val Arg Trp Gln Phe Leu Thr 
    210                 215                 220                 


Leu Arg Glu Arg Asn Lys Ile Lys Phe Gly Lys Arg Tyr Thr Ile Tyr 
225                 230                 235                 240 


Ser Pro Lys Asp Gly Gln Pro Cys Met Asp His Asp Arg Gln Thr Gly 
                245                 250                 255     


Glu Gly Val Gly Pro Gln Glu Tyr Thr Leu Leu Lys Leu Lys Val Leu 
            260                 265                 270         


Glu Pro Tyr Pro Ser Lys Leu Ser Gly Leu Lys Gly Lys Asn Ile Phe 
        275                 280                 285             


Leu Val Ala Ala Thr Leu Arg Pro Glu Thr Met Phe Gly Gln Thr Asn 
    290                 295                 300                 


Cys Trp Val Arg Pro Asp Met Lys Tyr Ile Gly Phe Glu Thr Val Asn 
305                 310                 315                 320 


Gly Asp Ile Phe Ile Cys Thr Gln Lys Ala Ala Arg Asn Met Ser Tyr 
                325                 330                 335     


Gln Gly Phe Thr Lys Asp Asn Gly Val Val Pro Val Val Lys Glu Leu 
            340                 345                 350         


Met Gly Glu Glu Ile Leu Gly Ala Ser Leu Ser Ala Pro Leu Thr Ser 
        355                 360                 365             


Tyr Lys Val Ile Tyr Val Leu Pro Met Leu Thr Ile Lys Glu Asp Lys 
    370                 375                 380                 


Gly Thr Gly Val Val Thr Ser Val Pro Ser Asp Ser Pro Asp Asp Ile 
385                 390                 395                 400 


Ala Ala Leu Arg Asp Leu Lys Lys Lys Gln Ala Leu Arg Ala Lys Tyr 
                405                 410                 415     


Gly Ile Arg Asp Asp Met Val Leu Pro Phe Glu Pro Val Pro Val Ile 
            420                 425                 430         


Glu Ile Pro Gly Phe Gly Asn Leu Ser Ala Val Thr Ile Cys Asp Glu 
        435                 440                 445             


Leu Lys Ile Gln Ser Gln Asn Asp Arg Glu Lys Leu Ala Glu Ala Lys 
    450                 455                 460                 


Glu Lys Ile Tyr Leu Lys Gly Phe Tyr Glu Gly Ile Met Leu Val Asp 
465                 470                 475                 480 


Gly Phe Lys Gly Gln Lys Val Gln Asp Val Lys Lys Thr Ile Gln Lys 
                485                 490                 495     


Lys Met Ile Asp Ala Gly Asp Ala Leu Ile Tyr Met Glu Pro Glu Lys 
            500                 505                 510         


Gln Val Met Ser Arg Ser Ser Asp Glu Cys Val Val Ala Leu Cys Asp 
        515                 520                 525             


Gln Trp Tyr Leu Asp Tyr Gly Glu Glu Asn Trp Lys Lys Gln Thr Ser 
    530                 535                 540                 


Gln Cys Leu Lys Asn Leu Glu Thr Phe Cys Glu Glu Thr Arg Arg Asn 
545                 550                 555                 560 


Phe Glu Ala Thr Leu Gly Trp Leu Gln Glu His Ala Cys Ser Arg Thr 
                565                 570                 575     


Tyr Gly Leu Gly Thr His Leu Pro Trp Asp Glu Gln Trp Leu Ile Glu 
            580                 585                 590         


Ser Leu Ser Asp Ser Thr Ile Tyr Met Ala Phe Tyr Thr Val Ala His 
        595                 600                 605             


Leu Leu Gln Gly Gly Asn Leu His Gly Gln Ala Glu Ser Pro Leu Gly 
    610                 615                 620                 


Ile Arg Pro Gln Gln Met Thr Lys Glu Val Trp Asp Tyr Val Phe Phe 
625                 630                 635                 640 


Lys Glu Ala Pro Phe Pro Lys Thr Gln Ile Ala Lys Glu Lys Leu Asp 
                645                 650                 655     


Gln Leu Lys Gln Glu Phe Glu Phe Trp Tyr Pro Val Asp Leu Arg Val 
            660                 665                 670         


Ser Gly Lys Asp Leu Val Pro Asn His Leu Ser Tyr Tyr Leu Tyr Asn 
        675                 680                 685             


His Val Ala Met Trp Pro Glu Gln Ser Asp Lys Trp Pro Thr Ala Val 
    690                 695                 700                 


Arg Ala Asn Gly His Leu Leu Leu Asn Ser Glu Lys Met Ser Lys Ser 
705                 710                 715                 720 


Thr Gly Asn Phe Leu Thr Leu Thr Gln Ala Ile Asp Lys Phe Ser Ala 
                725                 730                 735     


Asp Gly Met Arg Leu Ala Leu Ala Asp Ala Gly Asp Thr Val Glu Asp 
            740                 745                 750         


Ala Asn Phe Val Glu Ala Met Ala Asp Ala Gly Ile Leu Arg Leu Tyr 
        755                 760                 765             


Thr Trp Val Glu Trp Val Lys Glu Met Val Ala Asn Trp Asp Ser Leu 
    770                 775                 780                 


Arg Ser Gly Pro Ala Ser Thr Phe Asn Asp Arg Val Phe Ala Ser Glu 
785                 790                 795                 800 


Leu Asn Ala Gly Ile Ile Lys Thr Asp Gln Asn Tyr Glu Lys Met Met 
                805                 810                 815     


Phe Lys Glu Ala Leu Lys Thr Gly Phe Phe Glu Phe Gln Ala Ala Lys 
            820                 825                 830         


Asp Lys Tyr Arg Glu Leu Ala Val Glu Gly Met His Arg Glu Leu Val 
        835                 840                 845             


Phe Arg Phe Ile Glu Val Gln Thr Leu Leu Leu Ala Pro Phe Cys Pro 
    850                 855                 860                 


His Leu Cys Glu His Ile Trp Thr Leu Leu Gly Lys Pro Asp Ser Ile 
865                 870                 875                 880 


Met Asn Ala Ser Trp Pro Val Ala Gly Pro Val Asn Glu Val Leu Ile 
                885                 890                 895     


His Ser Ser Gln Tyr Leu Met Glu Val Thr His Asp Leu Arg Leu Arg 
            900                 905                 910         


Leu Lys Asn Tyr Met Met Pro Ala Lys Gly Lys Lys Thr Asp Lys Gln 
        915                 920                 925             


Pro Leu Gln Lys Pro Ser His Cys Thr Ile Tyr Val Ala Lys Asn Tyr 
    930                 935                 940                 


Pro Pro Trp Gln His Thr Thr Leu Ser Val Leu Arg Lys His Phe Glu 
945                 950                 955                 960 


Ala Asn Asn Gly Lys Leu Pro Asp Asn Lys Val Ile Ala Ser Glu Leu 
                965                 970                 975     


Gly Ser Met Pro Glu Leu Lys Lys Tyr Met Lys Lys Val Met Pro Phe 
            980                 985                 990         


Val Ala Met Ile Lys Glu Asn Leu  Glu Lys Met Gly Pro  Arg Ile Leu 
        995                 1000                 1005             


Asp Leu  Gln Leu Glu Phe Asp  Glu Lys Ala Val Leu  Met Glu Asn 
    1010                 1015                 1020             


Ile Val  Tyr Leu Thr Asn Ser  Leu Glu Leu Glu His  Ile Glu Val 
    1025                 1030                 1035             


Lys Phe  Ala Ser Glu Ala Glu  Asp Lys Ile Arg Glu  Asp Cys Cys 
    1040                 1045                 1050             


Pro Gly  Lys Pro Leu Asn Val  Phe Arg Ile Glu Pro  Gly Val Ser 
    1055                 1060                 1065             


Val Ser  Leu Val Asn Pro Gln  Pro Ser Asn Gly His  Phe Ser Thr 
    1070                 1075                 1080             


Lys Ile  Glu Ile Arg Gln Gly  Asp Asn Cys Asp Ser  Ile Ile Arg 
    1085                 1090                 1095             


Arg Leu  Met Lys Met Asn Arg  Gly Ile Lys Asp Leu  Ser Lys Val 
    1100                 1105                 1110             


Lys Leu  Met Arg Phe Asp Asp  Pro Leu Leu Gly Pro  Arg Arg Val 
    1115                 1120                 1125             


Pro Val  Leu Gly Lys Glu Tyr  Thr Glu Lys Thr Pro  Ile Ser Glu 
    1130                 1135                 1140             


His Ala  Val Phe Asn Val Asp  Leu Met Ser Lys Lys  Ile His Leu 
    1145                 1150                 1155             


Thr Glu  Asn Gly Ile Arg Val  Asp Ile Gly Asp Thr  Ile Ile Tyr 
    1160                 1165                 1170             


Leu Val  His 
    1175     


<210>  1471
<211>  1341
<212>  PRT
<213>  Homo sapiens

<400>  1471

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Ala Pro Ala Ser Glu 
1               5                   10                  15      


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30          


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Leu Leu Gln Phe Leu Gln 
        35                  40                  45              


Glu Phe Ser Gln Gln Thr Ile Ser Arg Thr His Glu Ile Lys Lys Gln 
    50                  55                  60                  


Val Asp Gly Leu Ile Arg Glu Thr Lys Ala Thr Asp Cys Arg Leu His 
65                  70                  75                  80  


Asn Val Phe Asn Asp Phe Leu Met Leu Ser Asn Thr Gln Phe Ile Glu 
                85                  90                  95      


Asn Arg Val Tyr Asp Glu Glu Val Glu Glu Pro Val Leu Lys Ala Glu 
            100                 105                 110         


Ala Glu Lys Thr Glu Gln Glu Lys Thr Arg Glu Gln Lys Glu Val Asp 
        115                 120                 125             


Leu Ile Pro Lys Val Gln Glu Ala Val Asn Tyr Gly Leu Gln Val Leu 
    130                 135                 140                 


Asp Ser Ala Phe Glu Gln Leu Asp Ile Lys Ala Gly Asn Ser Asp Ser 
145                 150                 155                 160 


Glu Glu Asp Asp Ala Asn Gly Arg Val Glu Leu Ile Leu Glu Pro Lys 
                165                 170                 175     


Asp Leu Tyr Ile Asp Arg Pro Leu Pro Tyr Leu Ile Gly Ser Lys Leu 
            180                 185                 190         


Phe Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu 
        195                 200                 205             


Gly Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu 
    210                 215                 220                 


Lys Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn 
225                 230                 235                 240 


Glu Gln Asn Arg His Thr Thr Gln Met Ser Asp Glu Glu Glu Asp Asp 
                245                 250                 255     


Asp Gly Cys Asp Leu Phe Ala Asp Ser Glu Lys Glu Glu Glu Asp Ile 
            260                 265                 270         


Glu Asp Ile Glu Glu Asn Thr Arg Pro Lys Arg Ser Arg Pro Thr Ser 
        275                 280                 285             


Phe Ala Asp Glu Leu Ala Ala Arg Ile Lys Gly Asp Ala Val Gly Arg 
    290                 295                 300                 


Val Asp Glu Glu Pro Thr Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg 
305                 310                 315                 320 


Lys Thr Leu Lys Glu Lys Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu 
                325                 330                 335     


Glu Asp Asn Leu Phe Ala Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser 
            340                 345                 350         


Pro Phe Gly Ser Gly Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe 
        355                 360                 365             


Asp Asp Glu Asp Glu Glu Ser Asp Leu Phe Thr Glu Ala Pro Gln Asp 
    370                 375                 380                 


Arg Gln Ala Gly Ala Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro 
385                 390                 395                 400 


Gly Lys Lys Ile Pro Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr 
                405                 410                 415     


Asp Val Phe Gly Ala Ala Ser Val Pro Ser Met Lys Glu Pro Gln Lys 
            420                 425                 430         


Pro Glu Gln Pro Thr Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr 
        435                 440                 445             


Gly Leu Phe Asp Asp Asp Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser 
    450                 455                 460                 


Ala Pro His Ser Lys Pro Ser Lys Thr Gly Lys Val Gln Ser Thr Ala 
465                 470                 475                 480 


Asp Ile Phe Gly Asp Glu Glu Gly Asp Leu Phe Lys Glu Lys Ala Val 
                485                 490                 495     


Ala Ser Pro Glu Ala Thr Val Ser Gln Thr Asp Glu Asn Lys Ala Arg 
            500                 505                 510         


Ala Glu Lys Lys Val Thr Leu Ser Ser Ser Lys Asn Leu Lys Pro Ser 
        515                 520                 525             


Ser Glu Thr Lys Thr Gln Lys Gly Leu Phe Ser Asp Glu Glu Asp Ser 
    530                 535                 540                 


Glu Asp Leu Phe Ser Ser Gln Ser Ala Ser Lys Leu Lys Gly Ala Ser 
545                 550                 555                 560 


Leu Leu Pro Gly Lys Leu Pro Thr Leu Val Ser Leu Phe Asp Asp Glu 
                565                 570                 575     


Asp Glu Glu Asp Asn Leu Phe Gly Gly Thr Ala Ala Lys Lys Gln Thr 
            580                 585                 590         


Leu Cys Leu Gln Ala Gln Arg Glu Glu Lys Ala Lys Ala Ser Glu Leu 
        595                 600                 605             


Ser Lys Lys Lys Ala Ser Ala Leu Leu Phe Ser Ser Asp Glu Glu Asp 
    610                 615                 620                 


Gln Trp Asn Ile Pro Ala Ser Gln Thr His Leu Ala Ser Asp Ser Arg 
625                 630                 635                 640 


Ser Lys Gly Glu Pro Arg Asp Ser Gly Thr Leu Gln Ser Gln Glu Ala 
                645                 650                 655     


Lys Ala Val Lys Lys Thr Ser Leu Phe Glu Glu Asp Glu Glu Asp Asp 
            660                 665                 670         


Leu Phe Ala Ile Ala Lys Asp Ser Gln Lys Lys Thr Gln Arg Val Ser 
        675                 680                 685             


Leu Leu Phe Glu Asp Asp Val Asp Ser Gly Gly Ser Leu Phe Gly Ser 
    690                 695                 700                 


Pro Pro Thr Ser Val Pro Pro Ala Thr Lys Lys Lys Glu Thr Val Ser 
705                 710                 715                 720 


Glu Ala Pro Pro Leu Leu Phe Ser Asp Glu Glu Glu Lys Glu Ala Gln 
                725                 730                 735     


Leu Gly Val Lys Ser Val Asp Lys Lys Val Glu Ser Ala Lys Glu Ser 
            740                 745                 750         


Leu Lys Phe Gly Arg Thr Asp Val Ala Glu Ser Glu Lys Glu Gly Leu 
        755                 760                 765             


Leu Thr Arg Ser Ala Gln Glu Thr Val Lys His Ser Asp Leu Phe Ser 
    770                 775                 780                 


Ser Ser Ser Pro Trp Asp Lys Gly Thr Lys Pro Arg Thr Lys Thr Val 
785                 790                 795                 800 


Leu Ser Leu Phe Asp Glu Glu Glu Asp Lys Met Glu Asp Gln Asn Ile 
                805                 810                 815     


Ile Gln Ala Pro Gln Lys Glu Val Gly Lys Gly Arg Asp Pro Asp Ala 
            820                 825                 830         


His Pro Lys Ser Thr Gly Val Phe Gln Asp Glu Glu Leu Leu Phe Ser 
        835                 840                 845             


His Lys Leu Gln Lys Asp Asn Asp Pro Asp Val Asp Leu Phe Ala Gly 
    850                 855                 860                 


Thr Lys Lys Thr Lys Leu Leu Glu Pro Ser Val Gly Ser Leu Phe Gly 
865                 870                 875                 880 


Asp Asp Glu Asp Asp Asp Leu Phe Ser Ser Ala Lys Ser Gln Pro Leu 
                885                 890                 895     


Val Gln Glu Lys Lys Arg Val Val Lys Lys Asp His Ser Val Asp Ser 
            900                 905                 910         


Phe Lys Asn Gln Lys His Pro Glu Ser Ile Gln Gly Ser Lys Glu Lys 
        915                 920                 925             


Gly Ile Trp Lys Pro Glu Thr Pro Gln Asp Ser Ser Gly Leu Ala Pro 
    930                 935                 940                 


Phe Lys Thr Lys Glu Pro Ser Thr Arg Ile Gly Lys Ile Gln Ala Asn 
945                 950                 955                 960 


Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser Gln Ile 
                965                 970                 975     


Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser Ser Glu 
            980                 985                 990         


His Arg Arg Ser His Gly Leu Glu  Ser Val Pro Val Leu  Pro Gly Ser 
        995                 1000                 1005             


Gly Glu  Ala Gly Val Ser Phe  Asp Leu Pro Ala Gln  Ala Asp Thr 
    1010                 1015                 1020             


Leu His  Ser Ala Asn Lys Ser  Arg Val Lys Met Arg  Gly Lys Arg 
    1025                 1030                 1035             


Arg Pro  Gln Thr Arg Ala Ala  Arg Arg Leu Ala Ala  Gln Glu Ser 
    1040                 1045                 1050             


Ser Glu  Thr Glu Asp Met Ser  Val Pro Arg Gly Pro  Ile Ala Gln 
    1055                 1060                 1065             


Trp Ala  Asp Gly Ala Ile Ser  Pro Asn Gly His Arg  Pro Gln Leu 
    1070                 1075                 1080             


Arg Ala  Ala Ser Gly Glu Asp  Ser Thr Glu Glu Ala  Leu Ala Ala 
    1085                 1090                 1095             


Ala Ala  Ala Pro Trp Glu Gly  Gly Pro Val Pro Gly  Val Asp Arg 
    1100                 1105                 1110             


Ser Pro  Phe Ala Lys Ser Leu  Gly His Ser Arg Gly  Glu Ala Asp 
    1115                 1120                 1125             


Leu Phe  Asp Ser Gly Asp Ile  Phe Ser Thr Gly Thr  Gly Ser Gln 
    1130                 1135                 1140             


Ser Val  Glu Arg Thr Lys Pro  Lys Ala Lys Ile Ala  Glu Asn Pro 
    1145                 1150                 1155             


Ala Asn  Pro Pro Val Gly Gly  Lys Ala Lys Ser Pro  Met Phe Pro 
    1160                 1165                 1170             


Ala Leu  Gly Glu Ala Ser Ser  Asp Asp Asp Leu Phe  Gln Ser Ala 
    1175                 1180                 1185             


Lys Pro  Lys Pro Ala Lys Lys  Thr Asn Pro Phe Pro  Leu Leu Glu 
    1190                 1195                 1200             


Asp Glu  Asp Asp Leu Phe Thr  Asp Gln Lys Val Lys  Lys Asn Glu 
    1205                 1210                 1215             


Thr Lys  Ser Asn Ser Gln Gln  Asp Val Ile Leu Thr  Thr Gln Asp 
    1220                 1225                 1230             


Ile Phe  Glu Asp Asp Ile Phe  Ala Thr Glu Ala Ile  Lys Pro Ser 
    1235                 1240                 1245             


Gln Lys  Thr Arg Glu Lys Glu  Lys Thr Leu Glu Ser  Asn Leu Phe 
    1250                 1255                 1260             


Asp Asp  Asn Ile Asp Ile Phe  Ala Asp Leu Thr Val  Lys Pro Lys 
    1265                 1270                 1275             


Glu Lys  Ser Lys Lys Lys Val  Glu Ala Lys Ser Ile  Phe Asp Asp 
    1280                 1285                 1290             


Asp Met  Asp Asp Ile Phe Ser  Ser Gly Ile Gln Ala  Lys Thr Thr 
    1295                 1300                 1305             


Lys Pro  Lys Ser Arg Ser Ala  Gln Ala Ala Pro Glu  Pro Arg Phe 
    1310                 1315                 1320             


Glu His  Lys Val Ser Asn Ile  Phe Asp Asp Pro Leu  Asn Ala Phe 
    1325                 1330                 1335             


Gly Gly  Gln 
    1340     


<210>  1472
<211>  184
<212>  PRT
<213>  Homo sapiens

<400>  1472

Met Lys Pro Asp Glu Thr Pro Met Phe Asp Pro Ser Leu Leu Lys Glu 
1               5                   10                  15      


Val Asp Trp Ser Gln Asn Thr Ala Thr Phe Ser Pro Ala Ile Ser Pro 
            20                  25                  30          


Thr His Pro Gly Glu Gly Leu Val Leu Arg Pro Leu Cys Thr Ala Asp 
        35                  40                  45              


Leu Asn Arg Gly Phe Phe Lys Val Leu Gly Gln Leu Thr Glu Thr Gly 
    50                  55                  60                  


Val Val Ser Pro Glu Gln Phe Met Lys Ser Phe Glu His Met Lys Lys 
65                  70                  75                  80  


Ser Gly Asp Tyr Tyr Val Thr Val Val Glu Asp Val Thr Leu Gly Gln 
                85                  90                  95      


Ile Val Ala Thr Ala Thr Leu Ile Ile Glu His Lys Phe Ile His Ser 
            100                 105                 110         


Cys Ala Lys Arg Gly Arg Val Glu Asp Val Val Val Ser Asp Glu Cys 
        115                 120                 125             


Arg Gly Lys Gln Leu Gly Lys Leu Leu Leu Ser Thr Leu Thr Leu Leu 
    130                 135                 140                 


Ser Lys Lys Leu Asn Cys Tyr Lys Ile Thr Leu Glu Cys Leu Pro Gln 
145                 150                 155                 160 


Asn Val Gly Phe Tyr Lys Lys Phe Gly Tyr Thr Val Ser Glu Glu Asn 
                165                 170                 175     


Tyr Met Cys Arg Arg Phe Leu Lys 
            180                 


<210>  1473
<211>  442
<212>  PRT
<213>  Homo sapiens

<400>  1473

Met Gly Leu Ala Met Glu His Gly Gly Ser Tyr Ala Arg Ala Gly Gly 
1               5                   10                  15      


Ser Ser Arg Gly Cys Trp Tyr Tyr Leu Arg Tyr Phe Phe Leu Phe Val 
            20                  25                  30          


Ser Leu Ile Gln Phe Leu Ile Ile Leu Gly Leu Val Leu Phe Met Val 
        35                  40                  45              


Tyr Gly Asn Val His Val Ser Thr Glu Ser Asn Leu Gln Ala Thr Glu 
    50                  55                  60                  


Arg Arg Ala Glu Gly Leu Tyr Ser Gln Leu Leu Gly Leu Thr Ala Ser 
65                  70                  75                  80  


Gln Ser Asn Leu Thr Lys Glu Leu Asn Phe Thr Thr Arg Ala Lys Asp 
                85                  90                  95      


Ala Ile Met Gln Met Trp Leu Asn Ala Arg Arg Asp Leu Asp Arg Ile 
            100                 105                 110         


Asn Ala Ser Phe Arg Gln Cys Gln Gly Asp Arg Val Ile Tyr Thr Asn 
        115                 120                 125             


Asn Gln Arg Tyr Met Ala Ala Ile Ile Leu Ser Glu Lys Gln Cys Arg 
    130                 135                 140                 


Asp Gln Phe Lys Asp Met Asn Lys Ser Cys Asp Ala Leu Leu Phe Met 
145                 150                 155                 160 


Leu Asn Gln Lys Val Lys Thr Leu Glu Val Glu Ile Ala Lys Glu Lys 
                165                 170                 175     


Thr Ile Cys Thr Lys Asp Lys Glu Ser Val Leu Leu Asn Lys Arg Val 
            180                 185                 190         


Ala Glu Glu Gln Leu Val Glu Cys Val Lys Thr Arg Glu Leu Gln His 
        195                 200                 205             


Gln Glu Arg Gln Leu Ala Lys Glu Gln Leu Gln Lys Val Gln Ala Leu 
    210                 215                 220                 


Cys Leu Pro Leu Asp Lys Asp Lys Phe Glu Met Asp Leu Arg Asn Leu 
225                 230                 235                 240 


Trp Arg Asp Ser Ile Ile Pro Arg Ser Leu Asp Asn Leu Gly Tyr Asn 
                245                 250                 255     


Leu Tyr His Pro Leu Gly Ser Glu Leu Ala Ser Ile Arg Arg Ala Cys 
            260                 265                 270         


Asp His Met Pro Ser Leu Met Ser Ser Lys Val Glu Glu Leu Ala Arg 
        275                 280                 285             


Ser Leu Arg Ala Asp Ile Glu Arg Val Ala Arg Glu Asn Ser Asp Leu 
    290                 295                 300                 


Gln Arg Gln Lys Leu Glu Ala Gln Gln Gly Leu Arg Ala Ser Gln Glu 
305                 310                 315                 320 


Ala Lys Gln Lys Val Glu Lys Glu Ala Gln Ala Arg Glu Ala Lys Leu 
                325                 330                 335     


Gln Ala Glu Cys Ser Arg Gln Thr Gln Leu Ala Leu Glu Glu Lys Ala 
            340                 345                 350         


Val Leu Arg Lys Glu Arg Asp Asn Leu Ala Lys Glu Leu Glu Glu Lys 
        355                 360                 365             


Lys Arg Glu Ala Glu Gln Leu Arg Met Glu Leu Ala Ile Arg Asn Ser 
    370                 375                 380                 


Ala Leu Asp Thr Cys Ile Lys Thr Lys Ser Gln Pro Met Met Pro Val 
385                 390                 395                 400 


Ser Arg Pro Met Gly Pro Val Pro Asn Pro Gln Pro Ile Asp Pro Ala 
                405                 410                 415     


Ser Leu Glu Glu Phe Lys Arg Lys Ile Leu Glu Ser Gln Arg Pro Pro 
            420                 425                 430         


Ala Gly Ile Pro Val Ala Pro Ser Ser Gly 
        435                 440         


<210>  1474
<211>  399
<212>  PRT
<213>  Homo sapiens

<400>  1474

Met Ala Val Thr Met Leu Gln Asp Trp Cys Arg Trp Met Gly Val Asn 
1               5                   10                  15      


Ala Arg Arg Gly Leu Leu Ile Leu Gly Ile Pro Glu Asp Cys Asp Asp 
            20                  25                  30          


Ala Glu Phe Gln Glu Ser Leu Glu Ala Ala Leu Arg Pro Met Gly His 
        35                  40                  45              


Phe Thr Val Leu Gly Lys Val Phe Arg Glu Glu Asp Asn Ala Thr Ala 
    50                  55                  60                  


Ala Leu Val Glu Leu Asp Arg Glu Val Asn Tyr Ala Leu Val Pro Arg 
65                  70                  75                  80  


Glu Ile Pro Gly Thr Gly Gly Pro Trp Asn Val Val Phe Val Pro Arg 
                85                  90                  95      


Cys Ser Gly Glu Glu Phe Leu Gly Leu Gly Arg Val Phe His Phe Pro 
            100                 105                 110         


Glu Gln Glu Gly Gln Met Val Glu Ser Val Ala Gly Ala Leu Gly Val 
        115                 120                 125             


Gly Leu Arg Arg Val Cys Trp Leu Arg Ser Ile Gly Gln Ala Val Gln 
    130                 135                 140                 


Pro Trp Val Glu Ala Val Arg Tyr Gln Ser Leu Gly Val Phe Ser Gly 
145                 150                 155                 160 


Arg Asp Gln Pro Ala Pro Gly Glu Glu Ser Phe Glu Val Trp Leu Asp 
                165                 170                 175     


His Thr Thr Glu Met Leu His Val Trp Gln Gly Val Ser Glu Arg Glu 
            180                 185                 190         


Arg Arg Arg Arg Leu Leu Glu Gly Leu Arg Gly Thr Ala Leu Gln Leu 
        195                 200                 205             


Val His Ala Leu Leu Ala Glu Asn Pro Ala Arg Thr Ala Gln Asp Cys 
    210                 215                 220                 


Leu Ala Ala Leu Ala Gln Val Phe Gly Asp Asn Glu Ser Gln Ala Thr 
225                 230                 235                 240 


Ile Arg Val Lys Cys Leu Thr Ala Gln Gln Gln Ser Gly Glu Arg Leu 
                245                 250                 255     


Ser Ala Phe Val Leu Arg Leu Glu Val Leu Leu Gln Lys Ala Met Glu 
            260                 265                 270         


Lys Glu Ala Leu Ala Arg Ala Ser Ala Asp Arg Val Arg Leu Arg Gln 
        275                 280                 285             


Met Leu Thr Arg Ala His Leu Thr Glu Pro Leu Asp Glu Ala Leu Arg 
    290                 295                 300                 


Lys Leu Arg Met Ala Gly Arg Ser Pro Ser Phe Leu Glu Met Leu Gly 
305                 310                 315                 320 


Leu Val Arg Glu Ser Glu Ala Trp Glu Ala Ser Leu Ala Arg Ser Val 
                325                 330                 335     


Arg Ala Gln Thr Gln Glu Gly Ala Gly Ala Arg Ala Gly Ala Gln Ala 
            340                 345                 350         


Val Ala Arg Ala Ser Thr Lys Val Glu Ala Val Pro Gly Gly Pro Gly 
        355                 360                 365             


Arg Glu Pro Glu Gly Leu Arg Gln Ala Gly Gly Gln Glu Ala Glu Glu 
    370                 375                 380                 


Leu Leu Gln Glu Gly Leu Lys Pro Val Leu Glu Glu Cys Asp Asn 
385                 390                 395                 


<210>  1475
<211>  90
<212>  PRT
<213>  Homo sapiens

<400>  1475

Met Lys Phe Leu Ala Val Leu Val Leu Leu Gly Val Ser Ile Phe Leu 
1               5                   10                  15      


Val Ser Ala Gln Asn Pro Thr Thr Ala Ala Pro Ala Asp Thr Tyr Pro 
            20                  25                  30          


Ala Thr Gly Pro Ala Asp Asp Glu Ala Pro Asp Ala Glu Thr Thr Ala 
        35                  40                  45              


Ala Ala Thr Thr Ala Thr Thr Ala Ala Pro Thr Thr Ala Thr Thr Ala 
    50                  55                  60                  


Ala Ser Thr Thr Ala Arg Lys Asp Ile Pro Val Leu Pro Lys Trp Val 
65                  70                  75                  80  


Gly Asp Leu Pro Asn Gly Arg Val Cys Pro 
                85                  90  


<210>  1476
<211>  362
<212>  PRT
<213>  Homo sapiens

<400>  1476

Met Ala Glu Val Pro Pro Gly Pro Ser Ser Leu Leu Pro Pro Pro Ala 
1               5                   10                  15      


Pro Pro Ala Pro Ala Ala Val Glu Pro Arg Cys Pro Phe Pro Ala Gly 
            20                  25                  30          


Ala Ala Leu Ala Cys Cys Ser Glu Asp Glu Glu Asp Asp Glu Glu His 
        35                  40                  45              


Glu Gly Gly Gly Ser Arg Ser Pro Ala Gly Gly Glu Ser Ala Thr Val 
    50                  55                  60                  


Ala Ala Lys Gly His Pro Cys Leu Arg Cys Pro Gln Pro Pro Gln Glu 
65                  70                  75                  80  


Gln Gln Gln Leu Asn Gly Leu Ile Ser Pro Glu Leu Arg His Leu Arg 
                85                  90                  95      


Ala Ala Ala Ser Leu Lys Ser Lys Val Leu Ser Val Ala Glu Val Ala 
            100                 105                 110         


Ala Thr Thr Ala Thr Pro Asp Gly Gly Pro Arg Ala Thr Ala Thr Lys 
        115                 120                 125             


Gly Ala Gly Val His Ser Gly Glu Arg Pro Pro His Ser Leu Ser Ser 
    130                 135                 140                 


Asn Ala Arg Thr Ala Val Pro Ser Pro Val Glu Ala Ala Ala Ala Ser 
145                 150                 155                 160 


Asp Pro Ala Ala Ala Arg Asn Gly Leu Ala Glu Gly Thr Glu Gln Glu 
                165                 170                 175     


Glu Glu Glu Glu Asp Glu Gln Val Arg Leu Leu Ser Ser Ser Leu Thr 
            180                 185                 190         


Ala Asp Cys Ser Leu Arg Ser Pro Ser Gly Arg Glu Val Glu Pro Gly 
        195                 200                 205             


Glu Asp Arg Thr Ile Arg Tyr Val Arg Tyr Glu Ser Glu Leu Gln Met 
    210                 215                 220                 


Pro Asp Ile Met Arg Leu Ile Thr Lys Asp Leu Ser Glu Pro Tyr Ser 
225                 230                 235                 240 


Ile Tyr Thr Tyr Arg Tyr Phe Ile His Asn Trp Pro Gln Leu Cys Phe 
                245                 250                 255     


Leu Ala Met Val Gly Glu Glu Cys Val Gly Ala Ile Val Cys Lys Leu 
            260                 265                 270         


Asp Met His Lys Lys Met Phe Arg Arg Gly Tyr Ile Ala Met Leu Ala 
        275                 280                 285             


Val Asp Ser Lys Tyr Arg Arg Asn Gly Ile Gly Thr Asn Leu Val Lys 
    290                 295                 300                 


Lys Ala Ile Tyr Ala Met Val Glu Gly Asp Cys Asp Glu Val Val Leu 
305                 310                 315                 320 


Glu Thr Glu Ile Thr Asn Lys Ser Ala Leu Lys Leu Tyr Glu Asn Leu 
                325                 330                 335     


Gly Phe Val Arg Asp Lys Arg Leu Phe Arg Tyr Tyr Leu Asn Gly Val 
            340                 345                 350         


Asp Ala Leu Arg Leu Lys Leu Trp Leu Arg 
        355                 360         


<210>  1477
<211>  747
<212>  PRT
<213>  Homo sapiens

<400>  1477

Met Glu Val Lys Arg Leu Lys Val Thr Glu Leu Arg Ser Glu Leu Gln 
1               5                   10                  15      


Arg Arg Gly Leu Asp Ser Arg Gly Leu Lys Val Asp Leu Ala Gln Arg 
            20                  25                  30          


Leu Gln Glu Ala Leu Asp Ala Glu Met Leu Glu Asp Glu Ala Gly Gly 
        35                  40                  45              


Gly Gly Ala Gly Pro Gly Gly Ala Cys Lys Ala Glu Pro Arg Pro Val 
    50                  55                  60                  


Ala Ala Ser Gly Gly Gly Pro Gly Gly Asp Glu Glu Glu Asp Glu Glu 
65                  70                  75                  80  


Glu Glu Glu Glu Asp Glu Glu Ala Leu Leu Glu Asp Glu Asp Glu Glu 
                85                  90                  95      


Pro Pro Pro Ala Gln Ala Leu Gly Gln Ala Ala Gln Pro Pro Pro Glu 
            100                 105                 110         


Pro Pro Glu Ala Ala Ala Met Glu Ala Ala Ala Glu Pro Asp Ala Ser 
        115                 120                 125             


Glu Lys Pro Ala Glu Ala Thr Ala Gly Ser Gly Gly Val Asn Gly Gly 
    130                 135                 140                 


Glu Glu Gln Gly Leu Gly Lys Arg Glu Glu Asp Glu Pro Glu Glu Arg 
145                 150                 155                 160 


Ser Gly Asp Glu Thr Pro Gly Ser Glu Val Pro Gly Asp Lys Ala Ala 
                165                 170                 175     


Glu Glu Gln Gly Asp Asp Gln Asp Ser Glu Lys Ser Lys Pro Ala Gly 
            180                 185                 190         


Ser Asp Gly Glu Arg Arg Gly Val Lys Arg Gln Arg Asp Glu Lys Asp 
        195                 200                 205             


Glu His Gly Arg Ala Tyr Tyr Glu Phe Arg Glu Glu Ala Tyr His Ser 
    210                 215                 220                 


Arg Ser Lys Ser Pro Leu Pro Pro Glu Glu Glu Ala Lys Asp Glu Glu 
225                 230                 235                 240 


Glu Asp Gln Thr Leu Val Asn Leu Asp Thr Tyr Thr Ser Asp Leu His 
                245                 250                 255     


Phe Gln Val Ser Lys Asp Arg Tyr Gly Gly Gln Pro Leu Phe Ser Glu 
            260                 265                 270         


Lys Phe Pro Thr Leu Trp Ser Gly Ala Arg Ser Thr Tyr Gly Val Thr 
        275                 280                 285             


Lys Gly Lys Val Cys Phe Glu Ala Lys Val Thr Gln Asn Leu Pro Met 
    290                 295                 300                 


Lys Glu Gly Cys Thr Glu Val Ser Leu Leu Arg Val Gly Trp Ser Val 
305                 310                 315                 320 


Asp Phe Ser Arg Pro Gln Leu Gly Glu Asp Glu Phe Ser Tyr Gly Phe 
                325                 330                 335     


Asp Gly Arg Gly Leu Lys Ala Glu Asn Gly Gln Phe Glu Glu Phe Gly 
            340                 345                 350         


Gln Thr Phe Gly Glu Asn Asp Val Ile Gly Cys Phe Ala Asn Phe Glu 
        355                 360                 365             


Thr Glu Glu Val Glu Leu Ser Phe Ser Lys Asn Gly Glu Asp Leu Gly 
    370                 375                 380                 


Val Ala Phe Trp Ile Ser Lys Asp Ser Leu Ala Asp Arg Ala Leu Leu 
385                 390                 395                 400 


Pro His Val Leu Cys Lys Asn Cys Val Val Glu Leu Asn Phe Gly Gln 
                405                 410                 415     


Lys Glu Glu Pro Phe Phe Pro Pro Pro Glu Glu Phe Val Phe Ile His 
            420                 425                 430         


Ala Val Pro Val Glu Glu Arg Val Arg Thr Ala Val Pro Pro Lys Thr 
        435                 440                 445             


Ile Glu Glu Cys Glu Val Ile Leu Met Val Gly Leu Pro Gly Ser Gly 
    450                 455                 460                 


Lys Thr Gln Trp Ala Leu Lys Tyr Ala Lys Glu Asn Pro Glu Lys Arg 
465                 470                 475                 480 


Tyr Asn Val Leu Gly Ala Glu Thr Val Leu Asn Gln Met Arg Met Lys 
                485                 490                 495     


Gly Leu Glu Glu Pro Glu Met Asp Pro Lys Ser Arg Asp Leu Leu Val 
            500                 505                 510         


Gln Gln Ala Ser Gln Cys Leu Ser Lys Leu Val Gln Ile Ala Ser Arg 
        515                 520                 525             


Thr Lys Arg Asn Phe Ile Leu Asp Gln Cys Asn Val Tyr Asn Ser Gly 
    530                 535                 540                 


Gln Arg Arg Lys Leu Leu Leu Phe Lys Thr Phe Ser Arg Lys Val Val 
545                 550                 555                 560 


Val Val Val Pro Asn Glu Glu Asp Trp Lys Lys Arg Leu Glu Leu Arg 
                565                 570                 575     


Lys Glu Val Glu Gly Asp Asp Val Pro Glu Ser Ile Met Leu Glu Met 
            580                 585                 590         


Lys Ala Asn Phe Ser Leu Pro Glu Lys Cys Asp Tyr Met Asp Glu Val 
        595                 600                 605             


Thr Tyr Gly Glu Leu Glu Lys Glu Glu Ala Gln Pro Ile Val Thr Lys 
    610                 615                 620                 


Tyr Lys Glu Glu Ala Arg Lys Leu Leu Pro Pro Ser Glu Lys Arg Thr 
625                 630                 635                 640 


Asn Arg Arg Asn Asn Arg Asn Lys Arg Asn Arg Gln Asn Arg Ser Arg 
                645                 650                 655     


Gly Gln Gly Tyr Val Gly Gly Gln Arg Arg Gly Tyr Asp Asn Arg Ala 
            660                 665                 670         


Tyr Gly Gln Gln Tyr Trp Gly Gln Pro Gly Asn Arg Gly Gly Tyr Arg 
        675                 680                 685             


Asn Phe Tyr Asp Arg Tyr Arg Gly Asp Tyr Asp Arg Phe Tyr Gly Arg 
    690                 695                 700                 


Asp Tyr Glu Tyr Asn Arg Tyr Arg Asp Tyr Tyr Arg Gln Tyr Asn Arg 
705                 710                 715                 720 


Asp Trp Gln Ser Tyr Tyr Tyr His His Pro Gln Asp Arg Asp Arg Tyr 
                725                 730                 735     


Tyr Arg Asn Tyr Tyr Gly Tyr Gln Gly Tyr Arg 
            740                 745         


<210>  1478
<211>  107
<212>  PRT
<213>  Homo sapiens

<400>  1478

Met Ala Ala Trp Ser Pro Ala Ala Ala Ala Pro Leu Leu Arg Gly Ile 
1               5                   10                  15      


Arg Gly Leu Pro Leu His His Arg Met Phe Ala Thr Gln Thr Glu Gly 
            20                  25                  30          


Glu Leu Arg Val Thr Gln Ile Leu Lys Glu Lys Phe Pro Arg Ala Thr 
        35                  40                  45              


Ala Ile Lys Val Thr Asp Ile Ser Gly Gly Cys Gly Ala Met Tyr Glu 
    50                  55                  60                  


Ile Lys Ile Glu Ser Glu Glu Phe Lys Glu Lys Arg Thr Val Gln Gln 
65                  70                  75                  80  


His Gln Met Val Asn Gln Ala Leu Lys Glu Glu Ile Lys Glu Met His 
                85                  90                  95      


Gly Leu Arg Ile Phe Thr Ser Val Pro Lys Arg 
            100                 105         


<210>  1479
<211>  374
<212>  PRT
<213>  Homo sapiens

<400>  1479

Met Leu Ser Thr Ser Arg Ser Arg Phe Ile Arg Asn Thr Asn Glu Ser 
1               5                   10                  15      


Gly Glu Glu Val Thr Thr Phe Phe Asp Tyr Asp Tyr Gly Ala Pro Cys 
            20                  25                  30          


His Lys Phe Asp Val Lys Gln Ile Gly Ala Gln Leu Leu Pro Pro Leu 
        35                  40                  45              


Tyr Ser Leu Val Phe Ile Phe Gly Phe Val Gly Asn Met Leu Val Val 
    50                  55                  60                  


Leu Ile Leu Ile Asn Cys Lys Lys Leu Lys Cys Leu Thr Asp Ile Tyr 
65                  70                  75                  80  


Leu Leu Asn Leu Ala Ile Ser Asp Leu Leu Phe Leu Ile Thr Leu Pro 
                85                  90                  95      


Leu Trp Ala His Ser Ala Ala Asn Glu Trp Val Phe Gly Asn Ala Met 
            100                 105                 110         


Cys Lys Leu Phe Thr Gly Leu Tyr His Ile Gly Tyr Phe Gly Gly Ile 
        115                 120                 125             


Phe Phe Ile Ile Leu Leu Thr Ile Asp Arg Tyr Leu Ala Ile Val His 
    130                 135                 140                 


Ala Val Phe Ala Leu Lys Ala Arg Thr Val Thr Phe Gly Val Val Thr 
145                 150                 155                 160 


Ser Val Ile Thr Trp Leu Val Ala Val Phe Ala Ser Val Pro Gly Ile 
                165                 170                 175     


Ile Phe Thr Lys Cys Gln Lys Glu Asp Ser Val Tyr Val Cys Gly Pro 
            180                 185                 190         


Tyr Phe Pro Arg Gly Trp Asn Asn Phe His Thr Ile Met Arg Asn Ile 
        195                 200                 205             


Leu Gly Leu Val Leu Pro Leu Leu Ile Met Val Ile Cys Tyr Ser Gly 
    210                 215                 220                 


Ile Leu Lys Thr Leu Leu Arg Cys Arg Asn Glu Lys Lys Arg His Arg 
225                 230                 235                 240 


Ala Val Arg Val Ile Phe Thr Ile Met Ile Val Tyr Phe Leu Phe Trp 
                245                 250                 255     


Thr Pro Tyr Asn Ile Val Ile Leu Leu Asn Thr Phe Gln Glu Phe Phe 
            260                 265                 270         


Gly Leu Ser Asn Cys Glu Ser Thr Ser Gln Leu Asp Gln Ala Thr Gln 
        275                 280                 285             


Val Thr Glu Thr Leu Gly Met Thr His Cys Cys Ile Asn Pro Ile Ile 
    290                 295                 300                 


Tyr Ala Phe Val Gly Glu Lys Phe Arg Ser Leu Phe His Ile Ala Leu 
305                 310                 315                 320 


Gly Cys Arg Ile Ala Pro Leu Gln Lys Pro Val Cys Gly Gly Pro Gly 
                325                 330                 335     


Val Arg Pro Gly Lys Asn Val Lys Val Thr Thr Gln Gly Leu Leu Asp 
            340                 345                 350         


Gly Arg Gly Lys Gly Lys Ser Ile Gly Arg Ala Pro Glu Ala Ser Leu 
        355                 360                 365             


Gln Asp Lys Glu Gly Ala 
    370                 


<210>  1480
<211>  116
<212>  PRT
<213>  Homo sapiens

<400>  1480

Met Ser Trp Arg Gly Arg Ser Thr Tyr Arg Pro Arg Pro Arg Arg Tyr 
1               5                   10                  15      


Val Glu Pro Pro Glu Met Ile Gly Pro Met Arg Pro Glu Gln Phe Ser 
            20                  25                  30          


Asp Glu Val Glu Pro Ala Thr Pro Glu Glu Gly Glu Pro Ala Thr Gln 
        35                  40                  45              


Arg Gln Asp Pro Ala Ala Ala Gln Glu Gly Gln Asp Glu Gly Ala Ser 
    50                  55                  60                  


Ala Gly Gln Gly Pro Lys Pro Glu Ala His Ser Gln Glu Gln Gly His 
65                  70                  75                  80  


Pro Gln Thr Gly Cys Glu Cys Glu Asp Gly Pro Asp Gly Gln Glu Met 
                85                  90                  95      


Asp Pro Pro Asn Pro Glu Glu Val Lys Thr Pro Glu Glu Gly Glu Lys 
            100                 105                 110         


Gln Ser Gln Cys 
        115     


<210>  1481
<211>  381
<212>  PRT
<213>  Homo sapiens

<400>  1481

Met Pro Phe Ser Asn Ser His Asn Ala Leu Lys Leu Arg Phe Pro Ala 
1               5                   10                  15      


Glu Asp Glu Phe Pro Asp Leu Ser Ala His Asn Asn His Met Ala Lys 
            20                  25                  30          


Val Leu Thr Pro Glu Leu Tyr Ala Glu Leu Arg Ala Lys Ser Thr Pro 
        35                  40                  45              


Ser Gly Phe Thr Leu Asp Asp Val Ile Gln Thr Gly Val Asp Asn Pro 
    50                  55                  60                  


Gly His Pro Tyr Ile Met Thr Val Gly Cys Val Ala Gly Asp Glu Glu 
65                  70                  75                  80  


Ser Tyr Glu Val Phe Lys Asp Leu Phe Asp Pro Ile Ile Glu Asp Arg 
                85                  90                  95      


His Gly Gly Tyr Lys Pro Ser Asp Glu His Lys Thr Asp Leu Asn Pro 
            100                 105                 110         


Asp Asn Leu Gln Gly Gly Asp Asp Leu Asp Pro Asn Tyr Val Leu Ser 
        115                 120                 125             


Ser Arg Val Arg Thr Gly Arg Ser Ile Arg Gly Phe Cys Leu Pro Pro 
    130                 135                 140                 


His Cys Ser Arg Gly Glu Arg Arg Ala Ile Glu Lys Leu Ala Val Glu 
145                 150                 155                 160 


Ala Leu Ser Ser Leu Asp Gly Asp Leu Ala Gly Arg Tyr Tyr Ala Leu 
                165                 170                 175     


Lys Ser Met Thr Glu Ala Glu Gln Gln Gln Leu Ile Asp Asp His Phe 
            180                 185                 190         


Leu Phe Asp Lys Pro Val Ser Pro Leu Leu Leu Ala Ser Gly Met Ala 
        195                 200                 205             


Arg Asp Trp Pro Asp Ala Arg Gly Ile Trp His Asn Asp Asn Lys Thr 
    210                 215                 220                 


Phe Leu Val Trp Val Asn Glu Glu Asp His Leu Arg Val Ile Ser Met 
225                 230                 235                 240 


Gln Lys Gly Gly Asn Met Lys Glu Val Phe Thr Arg Phe Cys Thr Gly 
                245                 250                 255     


Leu Thr Gln Ile Glu Thr Leu Phe Lys Ser Lys Asp Tyr Glu Phe Met 
            260                 265                 270         


Trp Asn Pro His Leu Gly Tyr Ile Leu Thr Cys Pro Ser Asn Leu Gly 
        275                 280                 285             


Thr Gly Leu Arg Ala Gly Val His Ile Lys Leu Pro Asn Leu Gly Lys 
    290                 295                 300                 


His Glu Lys Phe Ser Glu Val Leu Lys Arg Leu Arg Leu Gln Lys Arg 
305                 310                 315                 320 


Gly Thr Gly Gly Val Asp Thr Ala Ala Val Gly Gly Val Phe Asp Val 
                325                 330                 335     


Ser Asn Ala Asp Arg Leu Gly Phe Ser Glu Val Glu Leu Val Gln Met 
            340                 345                 350         


Val Val Asp Gly Val Lys Leu Leu Ile Glu Met Glu Gln Arg Leu Glu 
        355                 360                 365             


Gln Gly Gln Ala Ile Asp Asp Leu Met Pro Ala Gln Lys 
    370                 375                 380     


<210>  1482
<211>  232
<212>  PRT
<213>  Homo sapiens

<400>  1482

Met His Arg Arg Arg Ser Arg Ser Cys Arg Glu Asp Gln Lys Pro Val 
1               5                   10                  15      


Met Asp Asp Gln Arg Asp Leu Ile Ser Asn Asn Glu Gln Leu Pro Met 
            20                  25                  30          


Leu Gly Arg Arg Pro Gly Ala Pro Glu Ser Lys Cys Ser Arg Gly Ala 
        35                  40                  45              


Leu Tyr Thr Gly Phe Ser Ile Leu Val Thr Leu Leu Leu Ala Gly Gln 
    50                  55                  60                  


Ala Thr Thr Ala Tyr Phe Leu Tyr Gln Gln Gln Gly Arg Leu Asp Lys 
65                  70                  75                  80  


Leu Thr Val Thr Ser Gln Asn Leu Gln Leu Glu Asn Leu Arg Met Lys 
                85                  90                  95      


Leu Pro Lys Pro Pro Lys Pro Val Ser Lys Met Arg Met Ala Thr Pro 
            100                 105                 110         


Leu Leu Met Gln Ala Leu Pro Met Gly Ala Leu Pro Gln Gly Pro Met 
        115                 120                 125             


Gln Asn Ala Thr Lys Tyr Gly Asn Met Thr Glu Asp His Val Met His 
    130                 135                 140                 


Leu Leu Gln Asn Ala Asp Pro Leu Lys Val Tyr Pro Pro Leu Lys Gly 
145                 150                 155                 160 


Ser Phe Pro Glu Asn Leu Arg His Leu Lys Asn Thr Met Glu Thr Ile 
                165                 170                 175     


Asp Trp Lys Val Phe Glu Ser Trp Met His His Trp Leu Leu Phe Glu 
            180                 185                 190         


Met Ser Arg His Ser Leu Glu Gln Lys Pro Thr Asp Ala Pro Pro Lys 
        195                 200                 205             


Glu Ser Leu Glu Leu Glu Asp Pro Ser Ser Gly Leu Gly Val Thr Lys 
    210                 215                 220                 


Gln Asp Leu Gly Pro Val Pro Met 
225                 230         


<210>  1483
<211>  282
<212>  PRT
<213>  Homo sapiens

<400>  1483

Met Pro Pro His His Leu Leu Pro Trp Leu Ala Gln Val Pro Ser Ala 
1               5                   10                  15      


Glu Gly Glu Leu Val Arg Leu Val Ser Arg Ala Gly Gly Arg Gly Ala 
            20                  25                  30          


Cys Phe Trp Pro Ala Val Thr Met Glu Met Ala Val Ala Ala Gly Cys 
        35                  40                  45              


Val Cys Lys Gly Gly Gly Cys Cys His Arg Glu Pro Ser Gln Asp His 
    50                  55                  60                  


His Glu Ser Gln Glu His Arg Gly Pro Leu Val Gly Ser Gln Thr Cys 
65                  70                  75                  80  


Leu Val His Gln Ala Glu Gly Thr Ala Glu Lys Val Ser Ser Leu Gly 
                85                  90                  95      


Lys Asp Trp His Lys Phe Cys Leu Lys Cys Glu Arg Cys Ser Lys Thr 
            100                 105                 110         


Leu Thr Pro Gly Gly His Ala Glu His Asp Gly Lys Pro Phe Cys His 
        115                 120                 125             


Lys Pro Cys Tyr Ala Thr Leu Phe Gly Pro Lys Gly Val Asn Ile Gly 
    130                 135                 140                 


Gly Ala Gly Ser Tyr Ile Tyr Glu Lys Pro Leu Ala Glu Gly Pro Gln 
145                 150                 155                 160 


Val Thr Gly Pro Ile Glu Val Pro Ala Ala Arg Ala Glu Glu Arg Lys 
                165                 170                 175     


Ala Ser Gly Pro Pro Lys Gly Pro Ser Arg Ala Ser Ser Val Thr Thr 
            180                 185                 190         


Phe Thr Gly Glu Pro Asn Thr Cys Pro Arg Cys Ser Lys Lys Val Tyr 
        195                 200                 205             


Phe Ala Glu Lys Val Thr Ser Leu Gly Lys Asp Trp His Arg Pro Cys 
    210                 215                 220                 


Leu Arg Cys Glu Arg Cys Gly Lys Thr Leu Thr Pro Gly Gly His Ala 
225                 230                 235                 240 


Glu His Asp Gly Gln Pro Tyr Cys His Lys Pro Cys Tyr Gly Ile Leu 
                245                 250                 255     


Phe Gly Pro Lys Gly Val Asn Thr Gly Ala Val Gly Ser Tyr Ile Tyr 
            260                 265                 270         


Asp Arg Asp Pro Glu Gly Lys Val Gln Pro 
        275                 280         


<210>  1484
<211>  288
<212>  PRT
<213>  Homo sapiens

<400>  1484

Met Ala Glu Lys Arg His Thr Arg Asp Ser Glu Ala Gln Arg Leu Pro 
1               5                   10                  15      


Asp Ser Phe Lys Asp Ser Pro Ser Lys Gly Leu Gly Pro Cys Gly Trp 
            20                  25                  30          


Ile Leu Val Ala Phe Ser Phe Leu Phe Thr Val Ile Thr Phe Pro Ile 
        35                  40                  45              


Ser Ile Trp Met Cys Ile Lys Ile Ile Lys Glu Tyr Glu Arg Ala Ile 
    50                  55                  60                  


Ile Phe Arg Leu Gly Arg Ile Leu Gln Gly Gly Ala Lys Gly Pro Gly 
65                  70                  75                  80  


Leu Phe Phe Ile Leu Pro Cys Thr Asp Ser Phe Ile Lys Val Asp Met 
                85                  90                  95      


Arg Thr Ile Ser Phe Asp Ile Pro Pro Gln Glu Ile Leu Thr Lys Asp 
            100                 105                 110         


Ser Val Thr Ile Ser Val Asp Gly Val Val Tyr Tyr Arg Val Gln Asn 
        115                 120                 125             


Ala Thr Leu Ala Val Ala Asn Ile Thr Asn Ala Asp Ser Ala Thr Arg 
    130                 135                 140                 


Leu Leu Ala Gln Thr Thr Leu Arg Asn Val Leu Gly Thr Lys Asn Leu 
145                 150                 155                 160 


Ser Gln Ile Leu Ser Asp Arg Glu Glu Ile Ala His Asn Met Gln Ser 
                165                 170                 175     


Thr Leu Asp Asp Ala Thr Asp Ala Trp Gly Ile Lys Val Glu Arg Val 
            180                 185                 190         


Glu Ile Lys Asp Val Lys Leu Pro Val Gln Leu Gln Arg Ala Met Ala 
        195                 200                 205             


Ala Glu Ala Glu Ala Ser Arg Glu Ala Arg Ala Lys Val Ile Ala Ala 
    210                 215                 220                 


Glu Gly Glu Met Asn Ala Ser Arg Ala Leu Lys Glu Ala Ser Met Val 
225                 230                 235                 240 


Ile Thr Glu Ser Pro Ala Ala Leu Gln Leu Arg Tyr Leu Gln Thr Leu 
                245                 250                 255     


Thr Thr Ile Ala Ala Glu Lys Asn Ser Thr Ile Val Phe Pro Leu Pro 
            260                 265                 270         


Ile Asp Met Leu Gln Gly Ile Ile Gly Ala Lys His Ser His Leu Gly 
        275                 280                 285             


<210>  1485
<211>  2639
<212>  PRT
<213>  Homo sapiens

<400>  1485

Met Ser Ser Ser His Ser Arg Ala Gly Gln Ser Ala Ala Gly Ala Ala 
1               5                   10                  15      


Pro Gly Gly Gly Val Asp Thr Arg Asp Ala Glu Met Pro Ala Thr Glu 
            20                  25                  30          


Lys Asp Leu Ala Glu Asp Ala Pro Trp Lys Lys Ile Gln Gln Asn Thr 
        35                  40                  45              


Phe Thr Arg Trp Cys Asn Glu His Leu Lys Cys Val Ser Lys Arg Ile 
    50                  55                  60                  


Ala Asn Leu Gln Thr Asp Leu Ser Asp Gly Leu Arg Leu Ile Ala Leu 
65                  70                  75                  80  


Leu Glu Val Leu Ser Gln Lys Lys Met His Arg Lys His Asn Gln Arg 
                85                  90                  95      


Pro Thr Phe Arg Gln Met Gln Leu Glu Asn Val Ser Val Ala Leu Glu 
            100                 105                 110         


Phe Leu Asp Arg Glu Ser Ile Lys Leu Val Ser Ile Asp Ser Lys Ala 
        115                 120                 125             


Ile Val Asp Gly Asn Leu Lys Leu Ile Leu Gly Leu Ile Trp Thr Leu 
    130                 135                 140                 


Ile Leu His Tyr Ser Ile Ser Met Pro Met Trp Asp Glu Glu Glu Asp 
145                 150                 155                 160 


Glu Glu Ala Lys Lys Gln Thr Pro Lys Gln Arg Leu Leu Gly Trp Ile 
                165                 170                 175     


Gln Asn Lys Leu Pro Gln Leu Pro Ile Thr Asn Phe Ser Arg Asp Trp 
            180                 185                 190         


Gln Ser Gly Arg Ala Leu Gly Ala Leu Val Asp Ser Cys Ala Pro Gly 
        195                 200                 205             


Leu Cys Pro Asp Trp Asp Ser Trp Asp Ala Ser Lys Pro Val Thr Asn 
    210                 215                 220                 


Ala Arg Glu Ala Met Gln Gln Ala Asp Asp Trp Leu Gly Ile Pro Gln 
225                 230                 235                 240 


Val Ile Thr Pro Glu Glu Ile Val Asp Pro Asn Val Asp Glu His Ser 
                245                 250                 255     


Val Met Thr Tyr Leu Ser Gln Phe Pro Lys Ala Lys Leu Lys Pro Gly 
            260                 265                 270         


Ala Pro Leu Arg Pro Lys Leu Asn Pro Lys Lys Ala Arg Ala Tyr Gly 
        275                 280                 285             


Pro Gly Ile Glu Pro Thr Gly Asn Met Val Lys Lys Arg Ala Glu Phe 
    290                 295                 300                 


Thr Val Glu Thr Arg Ser Ala Gly Gln Gly Glu Val Leu Val Tyr Val 
305                 310                 315                 320 


Glu Asp Pro Ala Gly His Gln Glu Glu Ala Lys Val Thr Ala Asn Asn 
                325                 330                 335     


Asp Lys Asn Arg Thr Phe Ser Val Trp Tyr Val Pro Glu Val Thr Gly 
            340                 345                 350         


Thr His Lys Val Thr Val Leu Phe Ala Gly Gln His Ile Ala Lys Ser 
        355                 360                 365             


Pro Phe Glu Val Tyr Val Asp Lys Ser Gln Gly Asp Ala Ser Lys Val 
    370                 375                 380                 


Thr Ala Gln Gly Pro Gly Leu Glu Pro Ser Gly Asn Ile Ala Asn Lys 
385                 390                 395                 400 


Thr Thr Tyr Phe Glu Ile Phe Thr Ala Gly Ala Gly Thr Gly Glu Val 
                405                 410                 415     


Glu Val Val Ile Gln Asp Pro Met Gly Gln Lys Gly Thr Val Glu Pro 
            420                 425                 430         


Gln Leu Glu Ala Arg Gly Asp Ser Thr Tyr Arg Cys Ser Tyr Gln Pro 
        435                 440                 445             


Thr Met Glu Gly Val His Thr Val His Val Thr Phe Ala Gly Val Pro 
    450                 455                 460                 


Ile Pro Arg Ser Pro Tyr Thr Val Thr Val Gly Gln Ala Cys Asn Pro 
465                 470                 475                 480 


Ser Ala Cys Arg Ala Val Gly Arg Gly Leu Gln Pro Lys Gly Val Arg 
                485                 490                 495     


Val Lys Glu Thr Ala Asp Phe Lys Val Tyr Thr Lys Gly Ala Gly Ser 
            500                 505                 510         


Gly Glu Leu Lys Val Thr Val Lys Gly Pro Lys Gly Glu Glu Arg Val 
        515                 520                 525             


Lys Gln Lys Asp Leu Gly Asp Gly Val Tyr Gly Phe Glu Tyr Tyr Pro 
    530                 535                 540                 


Met Val Pro Gly Thr Tyr Ile Val Thr Ile Thr Trp Gly Gly Gln Asn 
545                 550                 555                 560 


Ile Gly Arg Ser Pro Phe Glu Val Lys Val Gly Thr Glu Cys Gly Asn 
                565                 570                 575     


Gln Lys Val Arg Ala Trp Gly Pro Gly Leu Glu Gly Gly Val Val Gly 
            580                 585                 590         


Lys Ser Ala Asp Phe Val Val Glu Ala Ile Gly Asp Asp Val Gly Thr 
        595                 600                 605             


Leu Gly Phe Ser Val Glu Gly Pro Ser Gln Ala Lys Ile Glu Cys Asp 
    610                 615                 620                 


Asp Lys Gly Asp Gly Ser Cys Asp Val Arg Tyr Trp Pro Gln Glu Ala 
625                 630                 635                 640 


Gly Glu Tyr Ala Val His Val Leu Cys Asn Ser Glu Asp Ile Arg Leu 
                645                 650                 655     


Ser Pro Phe Met Ala Asp Ile Arg Asp Ala Pro Gln Asp Phe His Pro 
            660                 665                 670         


Asp Arg Val Lys Ala Arg Gly Pro Gly Leu Glu Lys Thr Gly Val Ala 
        675                 680                 685             


Val Asn Lys Pro Ala Glu Phe Thr Val Asp Ala Lys His Gly Gly Lys 
    690                 695                 700                 


Ala Pro Leu Arg Val Gln Val Gln Asp Asn Glu Gly Cys Pro Val Glu 
705                 710                 715                 720 


Ala Leu Val Lys Asp Asn Gly Asn Gly Thr Tyr Ser Cys Ser Tyr Val 
                725                 730                 735     


Pro Arg Lys Pro Val Lys His Thr Ala Met Val Ser Trp Gly Gly Val 
            740                 745                 750         


Ser Ile Pro Asn Ser Pro Phe Arg Val Asn Val Gly Ala Gly Ser His 
        755                 760                 765             


Pro Asn Lys Val Lys Val Tyr Gly Pro Gly Val Ala Lys Thr Gly Leu 
    770                 775                 780                 


Lys Ala His Glu Pro Thr Tyr Phe Thr Val Asp Cys Ala Glu Ala Gly 
785                 790                 795                 800 


Gln Gly Asp Val Ser Ile Gly Ile Lys Cys Ala Pro Gly Val Val Gly 
                805                 810                 815     


Pro Ala Glu Ala Asp Ile Asp Phe Asp Ile Ile Arg Asn Asp Asn Asp 
            820                 825                 830         


Thr Phe Thr Val Lys Tyr Thr Pro Arg Gly Ala Gly Ser Tyr Thr Ile 
        835                 840                 845             


Met Val Leu Phe Ala Asp Gln Ala Thr Pro Thr Ser Pro Ile Arg Val 
    850                 855                 860                 


Lys Val Glu Pro Ser His Asp Ala Ser Lys Val Lys Ala Glu Gly Pro 
865                 870                 875                 880 


Gly Leu Ser Arg Thr Gly Val Glu Leu Gly Lys Pro Thr His Phe Thr 
                885                 890                 895     


Val Asn Ala Lys Ala Ala Gly Lys Gly Lys Leu Asp Val Gln Phe Ser 
            900                 905                 910         


Gly Leu Thr Lys Gly Asp Ala Val Arg Asp Val Asp Ile Ile Asp His 
        915                 920                 925             


His Asp Asn Thr Tyr Thr Val Lys Tyr Thr Pro Val Gln Gln Gly Pro 
    930                 935                 940                 


Val Gly Val Asn Val Thr Tyr Gly Gly Asp Pro Ile Pro Lys Ser Pro 
945                 950                 955                 960 


Phe Ser Val Ala Val Ser Pro Ser Leu Asp Leu Ser Lys Ile Lys Val 
                965                 970                 975     


Ser Gly Leu Gly Glu Lys Val Asp Val Gly Lys Asp Gln Glu Phe Thr 
            980                 985                 990         


Val Lys Ser Lys Gly Ala Gly Gly  Gln Gly Lys Val Ala  Ser Lys Ile 
        995                 1000                 1005             


Val Gly  Pro Ser Gly Ala Ala  Val Pro Cys Lys Val  Glu Pro Gly 
    1010                 1015                 1020             


Leu Gly  Ala Asp Asn Ser Val  Val Arg Phe Leu Pro  Arg Glu Glu 
    1025                 1030                 1035             


Gly Pro  Tyr Glu Val Glu Val  Thr Tyr Asp Gly Val  Pro Val Pro 
    1040                 1045                 1050             


Gly Ser  Pro Phe Pro Leu Glu  Ala Val Ala Pro Thr  Lys Pro Ser 
    1055                 1060                 1065             


Lys Val  Lys Ala Phe Gly Pro  Gly Leu Gln Gly Gly  Ser Ala Gly 
    1070                 1075                 1080             


Ser Pro  Ala Arg Phe Thr Ile  Asp Thr Lys Gly Ala  Gly Thr Gly 
    1085                 1090                 1095             


Gly Leu  Gly Leu Thr Val Glu  Gly Pro Cys Glu Ala  Gln Leu Glu 
    1100                 1105                 1110             


Cys Leu  Asp Asn Gly Asp Gly  Thr Cys Ser Val Ser  Tyr Val Pro 
    1115                 1120                 1125             


Thr Glu  Pro Gly Asp Tyr Asn  Ile Asn Ile Leu Phe  Ala Asp Thr 
    1130                 1135                 1140             


His Ile  Pro Gly Ser Pro Phe  Lys Ala His Val Val  Pro Cys Phe 
    1145                 1150                 1155             


Asp Ala  Ser Lys Val Lys Cys  Ser Gly Pro Gly Leu  Glu Arg Ala 
    1160                 1165                 1170             


Thr Ala  Gly Glu Val Gly Gln  Phe Gln Val Asp Cys  Ser Ser Ala 
    1175                 1180                 1185             


Gly Ser  Ala Glu Leu Thr Ile  Glu Ile Cys Ser Glu  Ala Gly Leu 
    1190                 1195                 1200             


Pro Ala  Glu Val Tyr Ile Gln  Asp His Gly Asp Gly  Thr His Thr 
    1205                 1210                 1215             


Ile Thr  Tyr Ile Pro Leu Cys  Pro Gly Ala Tyr Thr  Val Thr Ile 
    1220                 1225                 1230             


Lys Tyr  Gly Gly Gln Pro Val  Pro Asn Phe Pro Ser  Lys Leu Gln 
    1235                 1240                 1245             


Val Glu  Pro Ala Val Asp Thr  Ser Gly Val Gln Cys  Tyr Gly Pro 
    1250                 1255                 1260             


Gly Ile  Glu Gly Gln Gly Val  Phe Arg Glu Ala Thr  Thr Glu Phe 
    1265                 1270                 1275             


Ser Val  Asp Ala Arg Ala Leu  Thr Gln Thr Gly Gly  Pro His Val 
    1280                 1285                 1290             


Lys Ala  Arg Val Ala Asn Pro  Ser Gly Asn Leu Thr  Glu Thr Tyr 
    1295                 1300                 1305             


Val Gln  Asp Arg Gly Asp Gly  Met Tyr Lys Val Glu  Tyr Thr Pro 
    1310                 1315                 1320             


Tyr Glu  Glu Gly Leu His Ser  Val Asp Val Thr Tyr  Asp Gly Ser 
    1325                 1330                 1335             


Pro Val  Pro Ser Ser Pro Phe  Gln Val Pro Val Thr  Glu Gly Cys 
    1340                 1345                 1350             


Asp Pro  Ser Arg Val Arg Val  His Gly Pro Gly Ile  Gln Ser Gly 
    1355                 1360                 1365             


Thr Thr  Asn Lys Pro Asn Lys  Phe Thr Val Glu Thr  Arg Gly Ala 
    1370                 1375                 1380             


Gly Thr  Gly Gly Leu Gly Leu  Ala Val Glu Gly Pro  Ser Glu Ala 
    1385                 1390                 1395             


Lys Met  Ser Cys Met Asp Asn  Lys Asp Gly Ser Cys  Ser Val Glu 
    1400                 1405                 1410             


Tyr Ile  Pro Tyr Glu Ala Gly  Thr Tyr Ser Leu Asn  Val Thr Tyr 
    1415                 1420                 1425             


Gly Gly  His Gln Val Pro Gly  Ser Pro Phe Lys Val  Pro Val His 
    1430                 1435                 1440             


Asp Val  Thr Asp Ala Ser Lys  Val Lys Cys Ser Gly  Pro Gly Leu 
    1445                 1450                 1455             


Ser Pro  Gly Met Val Arg Ala  Asn Leu Pro Gln Ser  Phe Gln Val 
    1460                 1465                 1470             


Asp Thr  Ser Lys Ala Gly Val  Ala Pro Leu Gln Val  Lys Val Gln 
    1475                 1480                 1485             


Gly Pro  Lys Gly Leu Val Glu  Pro Val Asp Val Val  Asp Asn Ala 
    1490                 1495                 1500             


Asp Gly  Thr Gln Thr Val Asn  Tyr Val Pro Ser Arg  Glu Gly Pro 
    1505                 1510                 1515             


Tyr Ser  Ile Ser Val Leu Tyr  Gly Asp Glu Glu Val  Pro Arg Ser 
    1520                 1525                 1530             


Pro Phe  Lys Val Lys Val Leu  Pro Thr His Asp Ala  Ser Lys Val 
    1535                 1540                 1545             


Lys Ala  Ser Gly Pro Gly Leu  Asn Thr Thr Gly Val  Pro Ala Ser 
    1550                 1555                 1560             


Leu Pro  Val Glu Phe Thr Ile  Asp Ala Lys Asp Ala  Gly Glu Gly 
    1565                 1570                 1575             


Leu Leu  Ala Val Gln Ile Thr  Asp Pro Glu Gly Lys  Pro Lys Lys 
    1580                 1585                 1590             


Thr His  Ile Gln Asp Asn His  Asp Gly Thr Tyr Thr  Val Ala Tyr 
    1595                 1600                 1605             


Val Pro  Asp Val Thr Gly Arg  Tyr Thr Ile Leu Ile  Lys Tyr Gly 
    1610                 1615                 1620             


Gly Asp  Glu Ile Pro Phe Ser  Pro Tyr Arg Val Arg  Ala Val Pro 
    1625                 1630                 1635             


Thr Gly  Asp Ala Ser Lys Cys  Thr Val Thr Gly Ala  Gly Ile Gly 
    1640                 1645                 1650             


Pro Thr  Ile Gln Ile Gly Glu  Glu Thr Val Ile Thr  Val Asp Thr 
    1655                 1660                 1665             


Lys Ala  Ala Gly Lys Gly Lys  Val Thr Cys Thr Val  Cys Thr Pro 
    1670                 1675                 1680             


Asp Gly  Ser Glu Val Asp Val  Asp Val Val Glu Asn  Glu Asp Gly 
    1685                 1690                 1695             


Thr Phe  Asp Ile Phe Tyr Thr  Ala Pro Gln Pro Gly  Lys Tyr Val 
    1700                 1705                 1710             


Ile Cys  Val Arg Phe Gly Gly  Glu His Val Pro Asn  Ser Pro Phe 
    1715                 1720                 1725             


Gln Val  Thr Ala Leu Ala Gly  Asp Gln Pro Ser Val  Gln Pro Pro 
    1730                 1735                 1740             


Leu Arg  Ser Gln Gln Leu Ala  Pro Gln Tyr Thr Tyr  Ala Gln Gly 
    1745                 1750                 1755             


Gly Gln  Gln Thr Trp Ala Pro  Glu Arg Pro Leu Val  Gly Val Asn 
    1760                 1765                 1770             


Gly Leu  Asp Val Thr Ser Leu  Arg Pro Phe Asp Leu  Val Ile Pro 
    1775                 1780                 1785             


Phe Thr  Ile Lys Lys Gly Glu  Ile Thr Gly Glu Val  Arg Met Pro 
    1790                 1795                 1800             


Ser Gly  Lys Val Ala Gln Pro  Thr Ile Thr Asp Asn  Lys Asp Gly 
    1805                 1810                 1815             


Thr Val  Thr Val Arg Tyr Ala  Pro Ser Glu Ala Gly  Leu His Glu 
    1820                 1825                 1830             


Met Asp  Ile Arg Tyr Asp Asn  Met His Ile Pro Gly  Ser Pro Leu 
    1835                 1840                 1845             


Gln Phe  Tyr Val Asp Tyr Val  Asn Cys Gly His Val  Thr Ala Tyr 
    1850                 1855                 1860             


Gly Pro  Gly Leu Thr His Gly  Val Val Asn Lys Pro  Ala Thr Phe 
    1865                 1870                 1875             


Thr Val  Asn Thr Lys Asp Ala  Gly Glu Gly Gly Leu  Ser Leu Ala 
    1880                 1885                 1890             


Ile Glu  Gly Pro Ser Lys Ala  Glu Ile Ser Cys Thr  Asp Asn Gln 
    1895                 1900                 1905             


Asp Gly  Thr Cys Ser Val Ser  Tyr Leu Pro Val Leu  Pro Gly Asp 
    1910                 1915                 1920             


Tyr Ser  Ile Leu Val Lys Tyr  Asn Glu Gln His Val  Pro Gly Ser 
    1925                 1930                 1935             


Pro Phe  Thr Ala Arg Val Thr  Gly Asp Asp Ser Met  Arg Met Ser 
    1940                 1945                 1950             


His Leu  Lys Val Gly Ser Ala  Ala Asp Ile Pro Ile  Asn Ile Ser 
    1955                 1960                 1965             


Glu Thr  Asp Leu Ser Leu Leu  Thr Ala Thr Val Val  Pro Pro Ser 
    1970                 1975                 1980             


Gly Arg  Glu Glu Pro Cys Leu  Leu Lys Arg Leu Arg  Asn Gly His 
    1985                 1990                 1995             


Val Gly  Ile Ser Phe Val Pro  Lys Glu Thr Gly Glu  His Leu Val 
    2000                 2005                 2010             


His Val  Lys Lys Asn Gly Gln  His Val Ala Ser Ser  Pro Ile Pro 
    2015                 2020                 2025             


Val Val  Ile Ser Gln Ser Glu  Ile Gly Asp Ala Ser  Arg Val Arg 
    2030                 2035                 2040             


Val Ser  Gly Gln Gly Leu His  Glu Gly His Thr Phe  Glu Pro Ala 
    2045                 2050                 2055             


Glu Phe  Ile Ile Asp Thr Arg  Asp Ala Gly Tyr Gly  Gly Leu Ser 
    2060                 2065                 2070             


Leu Ser  Ile Glu Gly Pro Ser  Lys Val Asp Ile Asn  Thr Glu Asp 
    2075                 2080                 2085             


Leu Glu  Asp Gly Thr Cys Arg  Val Thr Tyr Cys Pro  Thr Glu Pro 
    2090                 2095                 2100             


Gly Asn  Tyr Ile Ile Asn Ile  Lys Phe Ala Asp Gln  His Val Pro 
    2105                 2110                 2115             


Gly Ser  Pro Phe Ser Val Lys  Val Thr Gly Glu Gly  Arg Val Lys 
    2120                 2125                 2130             


Glu Ser  Ile Thr Arg Arg Arg  Arg Ala Pro Ser Val  Ala Asn Val 
    2135                 2140                 2145             


Gly Ser  His Cys Asp Leu Ser  Leu Lys Ile Pro Glu  Ile Ser Ile 
    2150                 2155                 2160             


Gln Asp  Met Thr Ala Gln Val  Thr Ser Pro Ser Gly  Lys Thr His 
    2165                 2170                 2175             


Glu Ala  Glu Ile Val Glu Gly  Glu Asn His Thr Tyr  Cys Ile Arg 
    2180                 2185                 2190             


Phe Val  Pro Ala Glu Met Gly  Thr His Thr Val Ser  Val Lys Tyr 
    2195                 2200                 2205             


Lys Gly  Gln His Val Pro Gly  Ser Pro Phe Gln Phe  Thr Val Gly 
    2210                 2215                 2220             


Pro Leu  Gly Glu Gly Gly Ala  His Lys Val Arg Ala  Gly Gly Pro 
    2225                 2230                 2235             


Gly Leu  Glu Arg Ala Glu Ala  Gly Val Pro Ala Glu  Phe Ser Ile 
    2240                 2245                 2250             


Trp Thr  Arg Glu Ala Gly Ala  Gly Gly Leu Ala Ile  Ala Val Glu 
    2255                 2260                 2265             


Gly Pro  Ser Lys Ala Glu Ile  Ser Phe Glu Asp Arg  Lys Asp Gly 
    2270                 2275                 2280             


Ser Cys  Gly Val Ala Tyr Val  Val Gln Glu Pro Gly  Asp Tyr Glu 
    2285                 2290                 2295             


Val Ser  Val Lys Phe Asn Glu  Glu His Ile Pro Asp  Ser Pro Phe 
    2300                 2305                 2310             


Val Val  Pro Val Ala Ser Pro  Ser Gly Asp Ala Arg  Arg Leu Thr 
    2315                 2320                 2325             


Val Ser  Ser Leu Gln Glu Ser  Gly Leu Lys Val Asn  Gln Pro Ala 
    2330                 2335                 2340             


Ser Phe  Ala Val Ser Leu Asn  Gly Ala Lys Gly Ala  Ile Asp Ala 
    2345                 2350                 2355             


Lys Val  His Ser Pro Ser Gly  Ala Leu Glu Glu Cys  Tyr Val Thr 
    2360                 2365                 2370             


Glu Ile  Asp Gln Asp Lys Tyr  Ala Val Arg Phe Ile  Pro Arg Glu 
    2375                 2380                 2385             


Asn Gly  Val Tyr Leu Ile Asp  Val Lys Phe Asn Gly  Thr His Ile 
    2390                 2395                 2400             


Pro Gly  Ser Pro Phe Lys Ile  Arg Val Gly Glu Pro  Gly His Gly 
    2405                 2410                 2415             


Gly Asp  Pro Gly Leu Val Ser  Ala Tyr Gly Ala Gly  Leu Glu Gly 
    2420                 2425                 2430             


Gly Val  Thr Gly Asn Pro Ala  Glu Phe Val Val Asn  Thr Ser Asn 
    2435                 2440                 2445             


Ala Gly  Ala Gly Ala Leu Ser  Val Thr Ile Asp Gly  Pro Ser Lys 
    2450                 2455                 2460             


Val Lys  Met Asp Cys Gln Glu  Cys Pro Glu Gly Tyr  Arg Val Thr 
    2465                 2470                 2475             


Tyr Thr  Pro Met Ala Pro Gly  Ser Tyr Leu Ile Ser  Ile Lys Tyr 
    2480                 2485                 2490             


Gly Gly  Pro Tyr His Ile Gly  Gly Ser Pro Phe Lys  Ala Lys Val 
    2495                 2500                 2505             


Thr Gly  Pro Arg Leu Val Ser  Asn His Ser Leu His  Glu Thr Ser 
    2510                 2515                 2520             


Ser Val  Phe Val Asp Ser Leu  Thr Lys Ala Thr Cys  Ala Pro Gln 
    2525                 2530                 2535             


His Gly  Ala Pro Gly Pro Gly  Pro Ala Asp Ala Ser  Lys Val Val 
    2540                 2545                 2550             


Ala Lys  Gly Leu Gly Leu Ser  Lys Ala Tyr Val Gly  Gln Lys Ser 
    2555                 2560                 2565             


Ser Phe  Thr Val Asp Cys Ser  Lys Ala Gly Asn Asn  Met Leu Leu 
    2570                 2575                 2580             


Val Gly  Val His Gly Pro Arg  Thr Pro Cys Glu Glu  Ile Leu Val 
    2585                 2590                 2595             


Lys His  Val Gly Ser Arg Leu  Tyr Ser Val Ser Tyr  Leu Leu Lys 
    2600                 2605                 2610             


Asp Lys  Gly Glu Tyr Thr Leu  Val Val Lys Trp Gly  Asp Glu His 
    2615                 2620                 2625             


Ile Pro  Gly Ser Pro Tyr Arg  Val Val Val Pro 
    2630                 2635                 


<210>  1486
<211>  572
<212>  PRT
<213>  Homo sapiens

<400>  1486

Met Glu Thr Pro Ser Gln Arg Arg Ala Thr Arg Ser Gly Ala Gln Ala 
1               5                   10                  15      


Ser Ser Thr Pro Leu Ser Pro Thr Arg Ile Thr Arg Leu Gln Glu Lys 
            20                  25                  30          


Glu Asp Leu Gln Glu Leu Asn Asp Arg Leu Ala Val Tyr Ile Asp Arg 
        35                  40                  45              


Val Arg Ser Leu Glu Thr Glu Asn Ala Gly Leu Arg Leu Arg Ile Thr 
    50                  55                  60                  


Glu Ser Glu Glu Val Val Ser Arg Glu Val Ser Gly Ile Lys Ala Ala 
65                  70                  75                  80  


Tyr Glu Ala Glu Leu Gly Asp Ala Arg Lys Thr Leu Asp Ser Val Ala 
                85                  90                  95      


Lys Glu Arg Ala Arg Leu Gln Leu Glu Leu Ser Lys Val Arg Glu Glu 
            100                 105                 110         


Phe Lys Glu Leu Lys Ala Arg Asn Thr Lys Lys Glu Gly Asp Leu Ile 
        115                 120                 125             


Ala Ala Gln Ala Arg Leu Lys Asp Leu Glu Ala Leu Leu Asn Ser Lys 
    130                 135                 140                 


Glu Ala Ala Leu Ser Thr Ala Leu Ser Glu Lys Arg Thr Leu Glu Gly 
145                 150                 155                 160 


Glu Leu His Asp Leu Arg Gly Gln Val Ala Lys Leu Glu Ala Ala Leu 
                165                 170                 175     


Gly Glu Ala Lys Lys Gln Leu Gln Asp Glu Met Leu Arg Arg Val Asp 
            180                 185                 190         


Ala Glu Asn Arg Leu Gln Thr Met Lys Glu Glu Leu Asp Phe Gln Lys 
        195                 200                 205             


Asn Ile Tyr Ser Glu Glu Leu Arg Glu Thr Lys Arg Arg His Glu Thr 
    210                 215                 220                 


Arg Leu Val Glu Ile Asp Asn Gly Lys Gln Arg Glu Phe Glu Ser Arg 
225                 230                 235                 240 


Leu Ala Asp Ala Leu Gln Glu Leu Arg Ala Gln His Glu Asp Gln Val 
                245                 250                 255     


Glu Gln Tyr Lys Lys Glu Leu Glu Lys Thr Tyr Ser Ala Lys Leu Asp 
            260                 265                 270         


Asn Ala Arg Gln Ser Ala Glu Arg Asn Ser Asn Leu Val Gly Ala Ala 
        275                 280                 285             


His Glu Glu Leu Gln Gln Ser Arg Ile Arg Ile Asp Ser Leu Ser Ala 
    290                 295                 300                 


Gln Leu Ser Gln Leu Gln Lys Gln Leu Ala Ala Lys Glu Ala Lys Leu 
305                 310                 315                 320 


Arg Asp Leu Glu Asp Ser Leu Ala Arg Glu Arg Asp Thr Ser Arg Arg 
                325                 330                 335     


Leu Leu Ala Glu Lys Glu Arg Glu Met Ala Glu Met Arg Ala Arg Met 
            340                 345                 350         


Gln Gln Gln Leu Asp Glu Tyr Gln Glu Leu Leu Asp Ile Lys Leu Ala 
        355                 360                 365             


Leu Asp Met Glu Ile His Ala Tyr Arg Lys Leu Leu Glu Gly Glu Glu 
    370                 375                 380                 


Glu Arg Leu Arg Leu Ser Pro Ser Pro Thr Ser Gln Arg Ser Arg Gly 
385                 390                 395                 400 


Arg Ala Ser Ser His Ser Ser Gln Thr Gln Gly Gly Gly Ser Val Thr 
                405                 410                 415     


Lys Lys Arg Lys Leu Glu Ser Thr Glu Ser Arg Ser Ser Phe Ser Gln 
            420                 425                 430         


His Ala Arg Thr Ser Gly Arg Val Ala Val Glu Glu Val Asp Glu Glu 
        435                 440                 445             


Gly Lys Phe Val Arg Leu Arg Asn Lys Ser Asn Glu Asp Gln Ser Met 
    450                 455                 460                 


Gly Asn Trp Gln Ile Lys Arg Gln Asn Gly Asp Asp Pro Leu Leu Thr 
465                 470                 475                 480 


Tyr Arg Phe Pro Pro Lys Phe Thr Leu Lys Ala Gly Gln Val Val Thr 
                485                 490                 495     


Ile Trp Ala Ala Gly Ala Gly Ala Thr His Ser Pro Pro Thr Asp Leu 
            500                 505                 510         


Val Trp Lys Ala Gln Asn Thr Trp Gly Cys Gly Asn Ser Leu Arg Thr 
        515                 520                 525             


Ala Leu Ile Asn Ser Thr Gly Glu Glu Val Ala Met Arg Lys Leu Val 
    530                 535                 540                 


Arg Ser Val Thr Val Val Glu Asp Asp Glu Asp Glu Asp Gly Asp Asp 
545                 550                 555                 560 


Leu Leu His His His His Val Ser Gly Ser Arg Arg 
                565                 570         


<210>  1487
<211>  484
<212>  PRT
<213>  Homo sapiens

<400>  1487

Met Thr Pro Gly Thr Gln Ser Pro Phe Phe Leu Leu Leu Leu Leu Thr 
1               5                   10                  15      


Val Leu Thr Ala Thr Thr Ala Pro Lys Pro Ala Thr Val Val Thr Gly 
            20                  25                  30          


Ser Gly His Ala Ser Ser Thr Pro Gly Gly Glu Lys Glu Thr Ser Ala 
        35                  40                  45              


Thr Gln Arg Ser Ser Val Pro Ser Ser Thr Glu Lys Asn Ala Val Ser 
    50                  55                  60                  


Met Thr Ser Ser Val Leu Ser Ser His Ser Pro Gly Ser Gly Ser Ser 
65                  70                  75                  80  


Thr Thr Gln Gly Gln Asp Val Thr Leu Ala Pro Ala Thr Glu Pro Ala 
                85                  90                  95      


Ser Gly Ser Ala Ala Thr Trp Gly Gln Asp Val Thr Ser Val Pro Val 
            100                 105                 110         


Thr Arg Pro Ala Leu Gly Ser Thr Thr Pro Pro Ala His Asp Val Thr 
        115                 120                 125             


Ser Ala Pro Asp Asn Lys Pro Ala Pro Gly Ser Thr Ala Pro Pro Ala 
    130                 135                 140                 


His Gly Val Thr Ser Ala Pro Asp Thr Arg Pro Ala Pro Gly Ser Thr 
145                 150                 155                 160 


Ala Pro Pro Ala His Gly Val Thr Ser Ala Pro Asp Asn Arg Pro Ala 
                165                 170                 175     


Leu Gly Ser Thr Ala Pro Pro Val His Asn Val Thr Ser Ala Ser Gly 
            180                 185                 190         


Ser Ala Ser Gly Ser Ala Ser Thr Leu Val His Asn Gly Thr Ser Ala 
        195                 200                 205             


Arg Ala Thr Thr Thr Pro Ala Ser Lys Ser Thr Pro Phe Ser Ile Pro 
    210                 215                 220                 


Ser His His Ser Asp Thr Pro Thr Thr Leu Ala Ser His Ser Thr Lys 
225                 230                 235                 240 


Thr Asp Ala Ser Ser Thr His His Ser Thr Val Pro Pro Leu Thr Ser 
                245                 250                 255     


Ser Asn His Ser Thr Ser Pro Gln Leu Ser Thr Gly Val Ser Phe Phe 
            260                 265                 270         


Phe Leu Ser Phe His Ile Ser Asn Leu Gln Phe Asn Ser Ser Leu Glu 
        275                 280                 285             


Asp Pro Ser Thr Asp Tyr Tyr Gln Glu Leu Gln Arg Asp Ile Ser Glu 
    290                 295                 300                 


Met Phe Leu Gln Ile Tyr Lys Gln Gly Gly Phe Leu Gly Leu Ser Asn 
305                 310                 315                 320 


Ile Lys Phe Arg Pro Gly Ser Val Val Val Gln Leu Thr Leu Ala Phe 
                325                 330                 335     


Arg Glu Gly Thr Ile Asn Val His Asp Val Glu Thr Gln Phe Asn Gln 
            340                 345                 350         


Tyr Lys Thr Glu Ala Ala Ser Arg Tyr Asn Leu Thr Ile Ser Asp Val 
        355                 360                 365             


Ser Val Ser Asp Val Pro Phe Pro Phe Ser Ala Gln Ser Gly Ala Gly 
    370                 375                 380                 


Val Pro Gly Trp Gly Ile Ala Leu Leu Val Leu Val Cys Val Leu Val 
385                 390                 395                 400 


Ala Leu Ala Ile Val Tyr Leu Ile Ala Leu Ala Val Cys Gln Cys Arg 
                405                 410                 415     


Arg Lys Asn Tyr Gly Gln Leu Asp Ile Phe Pro Ala Arg Asp Thr Tyr 
            420                 425                 430         


His Pro Met Ser Glu Tyr Pro Thr Tyr His Thr His Gly Arg Tyr Val 
        435                 440                 445             


Pro Pro Ser Ser Thr Asp Arg Ser Pro Tyr Glu Lys Val Ser Ala Gly 
    450                 455                 460                 


Asn Gly Gly Ser Ser Leu Ser Tyr Thr Asn Pro Ala Val Ala Ala Thr 
465                 470                 475                 480 


Ser Ala Asn Leu 
                


<210>  1488
<211>  417
<212>  PRT
<213>  Homo sapiens

<400>  1488

Met Ser Leu Ser Asn Lys Leu Thr Leu Asp Lys Leu Asp Val Lys Gly 
1               5                   10                  15      


Lys Arg Val Val Met Arg Val Asp Phe Asn Val Pro Met Lys Asn Asn 
            20                  25                  30          


Gln Ile Thr Asn Asn Gln Arg Ile Lys Ala Ala Val Pro Ser Ile Lys 
        35                  40                  45              


Phe Cys Leu Asp Asn Gly Ala Lys Ser Val Val Leu Met Ser His Leu 
    50                  55                  60                  


Gly Arg Pro Asp Gly Val Pro Met Pro Asp Lys Tyr Ser Leu Glu Pro 
65                  70                  75                  80  


Val Ala Val Glu Leu Lys Ser Leu Leu Gly Lys Asp Val Leu Phe Leu 
                85                  90                  95      


Lys Asp Cys Val Gly Pro Glu Val Glu Lys Ala Cys Ala Asn Pro Ala 
            100                 105                 110         


Ala Gly Ser Val Ile Leu Leu Glu Asn Leu Arg Phe His Val Glu Glu 
        115                 120                 125             


Glu Gly Lys Gly Lys Asp Ala Ser Gly Asn Lys Val Lys Ala Glu Pro 
    130                 135                 140                 


Ala Lys Ile Glu Ala Phe Arg Ala Ser Leu Ser Lys Leu Gly Asp Val 
145                 150                 155                 160 


Tyr Val Asn Asp Ala Phe Gly Thr Ala His Arg Ala His Ser Ser Met 
                165                 170                 175     


Val Gly Val Asn Leu Pro Gln Lys Ala Gly Gly Phe Leu Met Lys Lys 
            180                 185                 190         


Glu Leu Asn Tyr Phe Ala Lys Ala Leu Glu Ser Pro Glu Arg Pro Phe 
        195                 200                 205             


Leu Ala Ile Leu Gly Gly Ala Lys Val Ala Asp Lys Ile Gln Leu Ile 
    210                 215                 220                 


Asn Asn Met Leu Asp Lys Val Asn Glu Met Ile Ile Gly Gly Gly Met 
225                 230                 235                 240 


Ala Phe Thr Phe Leu Lys Val Leu Asn Asn Met Glu Ile Gly Thr Ser 
                245                 250                 255     


Leu Phe Asp Glu Glu Gly Ala Lys Ile Val Lys Asp Leu Met Ser Lys 
            260                 265                 270         


Ala Glu Lys Asn Gly Val Lys Ile Thr Leu Pro Val Asp Phe Val Thr 
        275                 280                 285             


Ala Asp Lys Phe Asp Glu Asn Ala Lys Thr Gly Gln Ala Thr Val Ala 
    290                 295                 300                 


Ser Gly Ile Pro Ala Gly Trp Met Gly Leu Asp Cys Gly Pro Glu Ser 
305                 310                 315                 320 


Ser Lys Lys Tyr Ala Glu Ala Val Thr Arg Ala Lys Gln Ile Val Trp 
                325                 330                 335     


Asn Gly Pro Val Gly Val Phe Glu Trp Glu Ala Phe Ala Arg Gly Thr 
            340                 345                 350         


Lys Ala Leu Met Asp Glu Val Val Lys Ala Thr Ser Arg Gly Cys Ile 
        355                 360                 365             


Thr Ile Ile Gly Gly Gly Asp Thr Ala Thr Cys Cys Ala Lys Trp Asn 
    370                 375                 380                 


Thr Glu Asp Lys Val Ser His Val Ser Thr Gly Gly Gly Ala Ser Leu 
385                 390                 395                 400 


Glu Leu Leu Glu Gly Lys Val Leu Pro Gly Val Asp Ala Leu Ser Asn 
                405                 410                 415     


Ile 
    


<210>  1489
<211>  810
<212>  PRT
<213>  Homo sapiens

<400>  1489

Met Glu His Lys Glu Val Val Leu Leu Leu Leu Leu Phe Leu Lys Ser 
1               5                   10                  15      


Gly Gln Gly Glu Pro Leu Asp Asp Tyr Val Asn Thr Gln Gly Ala Ser 
            20                  25                  30          


Leu Phe Ser Val Thr Lys Lys Gln Leu Gly Ala Gly Ser Ile Glu Glu 
        35                  40                  45              


Cys Ala Ala Lys Cys Glu Glu Asp Glu Glu Phe Thr Cys Arg Ala Phe 
    50                  55                  60                  


Gln Tyr His Ser Lys Glu Gln Gln Cys Val Ile Met Ala Glu Asn Arg 
65                  70                  75                  80  


Lys Ser Ser Ile Ile Ile Arg Met Arg Asp Val Val Leu Phe Glu Lys 
                85                  90                  95      


Lys Val Tyr Leu Ser Glu Cys Lys Thr Gly Asn Gly Lys Asn Tyr Arg 
            100                 105                 110         


Gly Thr Met Ser Lys Thr Lys Asn Gly Ile Thr Cys Gln Lys Trp Ser 
        115                 120                 125             


Ser Thr Ser Pro His Arg Pro Arg Phe Ser Pro Ala Thr His Pro Ser 
    130                 135                 140                 


Glu Gly Leu Glu Glu Asn Tyr Cys Arg Asn Pro Asp Asn Asp Pro Gln 
145                 150                 155                 160 


Gly Pro Trp Cys Tyr Thr Thr Asp Pro Glu Lys Arg Tyr Asp Tyr Cys 
                165                 170                 175     


Asp Ile Leu Glu Cys Glu Glu Glu Cys Met His Cys Ser Gly Glu Asn 
            180                 185                 190         


Tyr Asp Gly Lys Ile Ser Lys Thr Met Ser Gly Leu Glu Cys Gln Ala 
        195                 200                 205             


Trp Asp Ser Gln Ser Pro His Ala His Gly Tyr Ile Pro Ser Lys Phe 
    210                 215                 220                 


Pro Asn Lys Asn Leu Lys Lys Asn Tyr Cys Arg Asn Pro Asp Arg Glu 
225                 230                 235                 240 


Leu Arg Pro Trp Cys Phe Thr Thr Asp Pro Asn Lys Arg Trp Glu Leu 
                245                 250                 255     


Cys Asp Ile Pro Arg Cys Thr Thr Pro Pro Pro Ser Ser Gly Pro Thr 
            260                 265                 270         


Tyr Gln Cys Leu Lys Gly Thr Gly Glu Asn Tyr Arg Gly Asn Val Ala 
        275                 280                 285             


Val Thr Val Ser Gly His Thr Cys Gln His Trp Ser Ala Gln Thr Pro 
    290                 295                 300                 


His Thr His Asn Arg Thr Pro Glu Asn Phe Pro Cys Lys Asn Leu Asp 
305                 310                 315                 320 


Glu Asn Tyr Cys Arg Asn Pro Asp Gly Lys Arg Ala Pro Trp Cys His 
                325                 330                 335     


Thr Thr Asn Ser Gln Val Arg Trp Glu Tyr Cys Lys Ile Pro Ser Cys 
            340                 345                 350         


Asp Ser Ser Pro Val Ser Thr Glu Gln Leu Ala Pro Thr Ala Pro Pro 
        355                 360                 365             


Glu Leu Thr Pro Val Val Gln Asp Cys Tyr His Gly Asp Gly Gln Ser 
    370                 375                 380                 


Tyr Arg Gly Thr Ser Ser Thr Thr Thr Thr Gly Lys Lys Cys Gln Ser 
385                 390                 395                 400 


Trp Ser Ser Met Thr Pro His Arg His Gln Lys Thr Pro Glu Asn Tyr 
                405                 410                 415     


Pro Asn Ala Gly Leu Thr Met Asn Tyr Cys Arg Asn Pro Asp Ala Asp 
            420                 425                 430         


Lys Gly Pro Trp Cys Phe Thr Thr Asp Pro Ser Val Arg Trp Glu Tyr 
        435                 440                 445             


Cys Asn Leu Lys Lys Cys Ser Gly Thr Glu Ala Ser Val Val Ala Pro 
    450                 455                 460                 


Pro Pro Val Val Leu Leu Pro Asp Val Glu Thr Pro Ser Glu Glu Asp 
465                 470                 475                 480 


Cys Met Phe Gly Asn Gly Lys Gly Tyr Arg Gly Lys Arg Ala Thr Thr 
                485                 490                 495     


Val Thr Gly Thr Pro Cys Gln Asp Trp Ala Ala Gln Glu Pro His Arg 
            500                 505                 510         


His Ser Ile Phe Thr Pro Glu Thr Asn Pro Arg Ala Gly Leu Glu Lys 
        515                 520                 525             


Asn Tyr Cys Arg Asn Pro Asp Gly Asp Val Gly Gly Pro Trp Cys Tyr 
    530                 535                 540                 


Thr Thr Asn Pro Arg Lys Leu Tyr Asp Tyr Cys Asp Val Pro Gln Cys 
545                 550                 555                 560 


Ala Ala Pro Ser Phe Asp Cys Gly Lys Pro Gln Val Glu Pro Lys Lys 
                565                 570                 575     


Cys Pro Gly Arg Val Val Gly Gly Cys Val Ala His Pro His Ser Trp 
            580                 585                 590         


Pro Trp Gln Val Ser Leu Arg Thr Arg Phe Gly Met His Phe Cys Gly 
        595                 600                 605             


Gly Thr Leu Ile Ser Pro Glu Trp Val Leu Thr Ala Ala His Cys Leu 
    610                 615                 620                 


Glu Lys Ser Pro Arg Pro Ser Ser Tyr Lys Val Ile Leu Gly Ala His 
625                 630                 635                 640 


Gln Glu Val Asn Leu Glu Pro His Val Gln Glu Ile Glu Val Ser Arg 
                645                 650                 655     


Leu Phe Leu Glu Pro Thr Arg Lys Asp Ile Ala Leu Leu Lys Leu Ser 
            660                 665                 670         


Ser Pro Ala Val Ile Thr Asp Lys Val Ile Pro Ala Cys Leu Pro Ser 
        675                 680                 685             


Pro Asn Tyr Val Val Ala Asp Arg Thr Glu Cys Phe Ile Thr Gly Trp 
    690                 695                 700                 


Gly Glu Thr Gln Gly Thr Phe Gly Ala Gly Leu Leu Lys Glu Ala Gln 
705                 710                 715                 720 


Leu Pro Val Ile Glu Asn Lys Val Cys Asn Arg Tyr Glu Phe Leu Asn 
                725                 730                 735     


Gly Arg Val Gln Ser Thr Glu Leu Cys Ala Gly His Leu Ala Gly Gly 
            740                 745                 750         


Thr Asp Ser Cys Gln Gly Asp Ser Gly Gly Pro Leu Val Cys Phe Glu 
        755                 760                 765             


Lys Asp Lys Tyr Ile Leu Gln Gly Val Thr Ser Trp Gly Leu Gly Cys 
    770                 775                 780                 


Ala Arg Pro Asn Lys Pro Gly Val Tyr Val Arg Val Ser Arg Phe Val 
785                 790                 795                 800 


Thr Trp Ile Glu Gly Val Met Arg Asn Asn 
                805                 810 


<210>  1490
<211>  971
<212>  PRT
<213>  Homo sapiens

<400>  1490

Met Gly Gly Met Gly Thr Pro Gly Asp Leu His Ala Ala Cys Pro Ser 
1               5                   10                  15      


Thr Thr Arg Arg Asp Ala Leu Cys Leu Gly Pro Glu Phe Glu Phe Asp 
            20                  25                  30          


Leu Arg His Ser Ala Gly Cys Pro Gly Asp Leu Gly Phe Phe Pro Leu 
        35                  40                  45              


Asp Pro Asp Thr Glu Ala Gly Gly Ser Gly Cys Leu Pro Thr Trp Leu 
    50                  55                  60                  


Pro Leu Arg Arg Leu Ala Arg Gly Arg Leu Glu Val Thr Ala Asp Leu 
65                  70                  75                  80  


Ala Glu Arg Arg Arg Ile Arg Ser Ala Ile Arg Glu Leu Gln Arg Gln 
                85                  90                  95      


Glu Leu Glu Arg Glu Glu Glu Ala Leu Ala Ser Lys Arg Phe Arg Ala 
            100                 105                 110         


Glu Arg Gln Asp Asn Lys Glu Asn Trp Leu His Ser Gln Gln Arg Glu 
        115                 120                 125             


Ala Glu Gln Arg Ala Ala Leu Ala Arg Leu Ala Gly Gln Leu Glu Ser 
    130                 135                 140                 


Met Asn Asp Val Glu Glu Leu Thr Ala Leu Leu Arg Ser Ala Gly Glu 
145                 150                 155                 160 


Tyr Glu Glu Arg Lys Leu Ile Arg Ala Ala Ile Arg Arg Val Arg Ala 
                165                 170                 175     


Gln Glu Ile Glu Ala Ala Thr Leu Ala Gly Arg Leu Tyr Ser Gly Arg 
            180                 185                 190         


Pro Asn Ser Gly Ser Arg Glu Asp Ser Lys Gly Leu Ala Ala His Arg 
        195                 200                 205             


Leu Glu Gln Cys Glu Val Pro Glu Arg Glu Glu Gln Glu Gln Gln Ala 
    210                 215                 220                 


Glu Val Ser Lys Pro Thr Pro Thr Pro Glu Gly Thr Ser Gln Asp Val 
225                 230                 235                 240 


Thr Thr Val Thr Leu Leu Leu Arg Ala Pro Pro Gly Ser Thr Ser Ser 
                245                 250                 255     


Ser Pro Ala Ser Pro Ser Ser Ser Pro Thr Pro Ala Ser Pro Glu Pro 
            260                 265                 270         


Pro Leu Glu Pro Ala Glu Ala Gln Cys Leu Thr Ala Glu Val Pro Gly 
        275                 280                 285             


Ser Pro Glu Pro Pro Pro Ser Pro Pro Lys Thr Thr Ser Pro Glu Pro 
    290                 295                 300                 


Gln Glu Ser Pro Thr Leu Pro Ser Thr Glu Gly Gln Val Val Asn Lys 
305                 310                 315                 320 


Leu Leu Ser Gly Pro Lys Glu Thr Pro Ala Ala Gln Ser Pro Thr Arg 
                325                 330                 335     


Gly Pro Ser Asp Thr Lys Arg Ala Asp Val Ala Gly Pro Arg Pro Cys 
            340                 345                 350         


Gln Arg Ser Leu Ser Val Leu Ser Pro Arg Gln Pro Ala Gln Asn Arg 
        355                 360                 365             


Glu Ser Thr Pro Leu Ala Ser Gly Pro Ser Ser Phe Gln Arg Ala Gly 
    370                 375                 380                 


Ser Val Arg Asp Arg Val His Lys Phe Thr Ser Asp Ser Pro Met Ala 
385                 390                 395                 400 


Ala Arg Leu Gln Asp Gly Thr Pro Gln Ala Ala Leu Ser Pro Leu Thr 
                405                 410                 415     


Pro Ala Arg Leu Leu Gly Pro Ser Leu Thr Ser Thr Thr Pro Ala Ser 
            420                 425                 430         


Ser Ser Ser Gly Ser Ser Ser Arg Gly Pro Ser Asp Thr Ser Ser Arg 
        435                 440                 445             


Phe Ser Lys Glu Gln Arg Gly Val Ala Gln Pro Leu Ala Gln Leu Arg 
    450                 455                 460                 


Ser Cys Pro Gln Glu Glu Gly Pro Arg Gly Arg Gly Leu Ala Ala Arg 
465                 470                 475                 480 


Pro Leu Glu Asn Arg Ala Gly Gly Pro Val Ala Arg Ser Glu Glu Pro 
                485                 490                 495     


Gly Ala Pro Leu Pro Val Ala Val Gly Thr Ala Glu Pro Gly Gly Ser 
            500                 505                 510         


Met Lys Thr Thr Phe Thr Ile Glu Ile Lys Asp Gly Arg Gly Gln Ala 
        515                 520                 525             


Ser Thr Gly Arg Val Leu Leu Pro Thr Gly Asn Gln Arg Ala Glu Leu 
    530                 535                 540                 


Thr Leu Gly Leu Arg Ala Pro Pro Thr Leu Leu Ser Thr Ser Ser Gly 
545                 550                 555                 560 


Gly Lys Ser Thr Ile Thr Arg Val Asn Ser Pro Gly Thr Leu Ala Arg 
                565                 570                 575     


Leu Gly Ser Val Thr His Val Thr Ser Phe Ser His Ala Pro Pro Ser 
            580                 585                 590         


Ser Arg Gly Gly Cys Ser Ile Lys Met Glu Ala Glu Pro Ala Glu Pro 
        595                 600                 605             


Leu Ala Ala Ala Val Glu Ala Ala Asn Gly Ala Glu Gln Thr Arg Val 
    610                 615                 620                 


Asn Lys Ala Pro Glu Gly Arg Ser Pro Leu Ser Ala Glu Glu Leu Met 
625                 630                 635                 640 


Thr Ile Glu Asp Glu Gly Val Leu Asp Lys Met Leu Asp Gln Ser Thr 
                645                 650                 655     


Asp Phe Glu Glu Arg Lys Leu Ile Arg Ala Ala Leu Arg Glu Leu Arg 
            660                 665                 670         


Gln Arg Lys Arg Asp Gln Arg Asp Lys Glu Arg Glu Arg Arg Leu Gln 
        675                 680                 685             


Glu Ala Arg Gly Arg Pro Gly Glu Gly Arg Gly Asn Thr Ala Thr Glu 
    690                 695                 700                 


Thr Thr Thr Arg His Ser Gln Arg Ala Ala Asp Gly Ser Ala Val Ser 
705                 710                 715                 720 


Thr Val Thr Lys Thr Glu Arg Leu Val His Ser Asn Asp Gly Thr Arg 
                725                 730                 735     


Thr Ala Arg Thr Thr Thr Val Glu Ser Ser Phe Val Arg Arg Ser Glu 
            740                 745                 750         


Asn Gly Ser Gly Ser Thr Met Met Gln Thr Lys Thr Phe Ser Ser Ser 
        755                 760                 765             


Ser Ser Ser Lys Lys Met Gly Ser Ile Phe Asp Arg Glu Asp Gln Ala 
    770                 775                 780                 


Ser Pro Arg Ala Gly Ser Leu Ala Ala Leu Glu Lys Arg Gln Ala Glu 
785                 790                 795                 800 


Lys Lys Lys Glu Leu Met Lys Ala Gln Ser Leu Pro Lys Thr Ser Ala 
                805                 810                 815     


Ser Gln Ala Arg Lys Ala Met Ile Glu Lys Leu Glu Lys Glu Gly Ala 
            820                 825                 830         


Ala Gly Ser Pro Gly Gly Pro Arg Ala Ala Val Gln Arg Ser Thr Ser 
        835                 840                 845             


Phe Gly Val Pro Asn Ala Asn Ser Ile Lys Gln Met Leu Leu Asp Trp 
    850                 855                 860                 


Cys Arg Ala Lys Thr Arg Gly Tyr Glu His Val Asp Ile Gln Asn Phe 
865                 870                 875                 880 


Ser Ser Ser Trp Ser Asp Gly Met Ala Phe Cys Ala Leu Val His Asn 
                885                 890                 895     


Phe Phe Pro Glu Ala Phe Asp Tyr Gly Gln Leu Ser Pro Gln Asn Arg 
            900                 905                 910         


Arg Gln Asn Phe Glu Val Ala Phe Ser Ser Ala Glu Thr His Ala Asp 
        915                 920                 925             


Cys Pro Gln Leu Leu Asp Thr Glu Asp Met Val Arg Leu Arg Glu Pro 
    930                 935                 940                 


Asp Trp Lys Cys Val Tyr Thr Tyr Ile Gln Glu Phe Tyr Arg Cys Leu 
945                 950                 955                 960 


Val Gln Lys Gly Leu Val Lys Thr Lys Lys Ser 
                965                 970     


<210>  1491
<211>  559
<212>  PRT
<213>  Homo sapiens

<400>  1491

Met Pro Leu Val Lys Arg Asn Ile Asp Pro Arg His Leu Cys His Thr 
1               5                   10                  15      


Ala Leu Pro Arg Gly Ile Lys Asn Glu Leu Glu Cys Val Thr Asn Ile 
            20                  25                  30          


Ser Leu Ala Asn Ile Ile Arg Gln Leu Ser Ser Leu Ser Lys Tyr Ala 
        35                  40                  45              


Glu Asp Ile Phe Gly Glu Leu Phe Asn Glu Ala His Ser Phe Ser Phe 
    50                  55                  60                  


Arg Val Asn Ser Leu Gln Glu Arg Val Asp Arg Leu Ser Val Ser Val 
65                  70                  75                  80  


Thr Gln Leu Asp Pro Lys Glu Glu Glu Leu Ser Leu Gln Asp Ile Thr 
                85                  90                  95      


Met Arg Lys Ala Phe Arg Ser Ser Thr Ile Gln Asp Gln Gln Leu Phe 
            100                 105                 110         


Asp Arg Lys Thr Leu Pro Ile Pro Leu Gln Glu Thr Tyr Asp Val Cys 
        115                 120                 125             


Glu Gln Pro Pro Pro Leu Asn Ile Leu Thr Pro Tyr Arg Asp Asp Gly 
    130                 135                 140                 


Lys Glu Gly Leu Lys Phe Tyr Thr Asn Pro Ser Tyr Phe Phe Asp Leu 
145                 150                 155                 160 


Trp Lys Glu Lys Met Leu Gln Asp Thr Glu Asp Lys Arg Lys Glu Lys 
                165                 170                 175     


Arg Lys Gln Lys Gln Lys Asn Leu Asp Arg Pro His Glu Pro Glu Lys 
            180                 185                 190         


Val Pro Arg Ala Pro His Asp Arg Arg Arg Glu Trp Gln Lys Leu Ala 
        195                 200                 205             


Gln Gly Pro Glu Leu Ala Glu Asp Asp Ala Asn Leu Leu His Lys His 
    210                 215                 220                 


Ile Glu Val Ala Asn Gly Pro Ala Ser His Phe Glu Thr Arg Pro Gln 
225                 230                 235                 240 


Thr Tyr Val Asp His Met Asp Gly Ser Tyr Ser Leu Ser Ala Leu Pro 
                245                 250                 255     


Phe Ser Gln Met Ser Glu Leu Leu Thr Arg Ala Glu Glu Arg Val Leu 
            260                 265                 270         


Val Arg Pro His Glu Pro Pro Pro Pro Pro Pro Met His Gly Ala Gly 
        275                 280                 285             


Asp Ala Lys Pro Ile Pro Thr Cys Ile Ser Ser Ala Thr Gly Leu Ile 
    290                 295                 300                 


Glu Asn Arg Pro Gln Ser Pro Ala Thr Gly Arg Thr Pro Val Phe Val 
305                 310                 315                 320 


Ser Pro Thr Pro Pro Pro Pro Pro Pro Pro Leu Pro Ser Ala Leu Ser 
                325                 330                 335     


Thr Ser Ser Leu Arg Ala Ser Met Thr Ser Thr Pro Pro Pro Pro Val 
            340                 345                 350         


Pro Pro Pro Pro Pro Pro Pro Ala Thr Ala Leu Gln Ala Pro Ala Val 
        355                 360                 365             


Pro Pro Pro Pro Ala Pro Leu Gln Ile Ala Pro Gly Val Leu His Pro 
    370                 375                 380                 


Ala Pro Pro Pro Ile Ala Pro Pro Leu Val Gln Pro Ser Pro Pro Val 
385                 390                 395                 400 


Ala Arg Ala Ala Pro Val Cys Glu Thr Val Pro Val His Pro Leu Pro 
                405                 410                 415     


Gln Gly Glu Val Gln Gly Leu Pro Pro Pro Pro Pro Pro Pro Pro Leu 
            420                 425                 430         


Pro Pro Pro Gly Ile Arg Pro Ser Ser Pro Val Thr Val Thr Ala Leu 
        435                 440                 445             


Ala His Pro Pro Ser Gly Leu His Pro Thr Pro Ser Thr Ala Pro Gly 
    450                 455                 460                 


Pro His Val Pro Leu Met Pro Pro Ser Pro Pro Ser Gln Val Ile Pro 
465                 470                 475                 480 


Ala Ser Glu Pro Lys Arg His Pro Ser Thr Leu Pro Val Ile Ser Asp 
                485                 490                 495     


Ala Arg Ser Val Leu Leu Glu Ala Ile Arg Lys Gly Ile Gln Leu Arg 
            500                 505                 510         


Lys Val Glu Glu Gln Arg Glu Gln Glu Ala Lys His Glu Arg Ile Glu 
        515                 520                 525             


Asn Asp Val Ala Thr Ile Leu Ser Arg Arg Ile Ala Val Glu Tyr Ser 
    530                 535                 540                 


Asp Ser Glu Asp Asp Ser Glu Phe Asp Glu Val Asp Trp Leu Glu 
545                 550                 555                 


<210>  1492
<211>  341
<212>  PRT
<213>  Homo sapiens

<400>  1492

Met Thr Asp Gly Ile Leu Gly Lys Ala Ala Thr Met Glu Ile Pro Ile 
1               5                   10                  15      


His Gly Asn Gly Glu Ala Arg Gln Leu Pro Glu Asp Asp Gly Leu Glu 
            20                  25                  30          


Gln Asp Leu Gln Gln Val Met Val Ser Gly Pro Asn Leu Asn Glu Thr 
        35                  40                  45              


Ser Ile Val Ser Gly Gly Tyr Gly Gly Ser Gly Asp Gly Leu Ile Pro 
    50                  55                  60                  


Thr Gly Ser Gly Arg His Pro Ser His Ser Thr Thr Pro Ser Gly Pro 
65                  70                  75                  80  


Gly Asp Glu Val Ala Arg Gly Ile Ala Gly Glu Lys Phe Asp Ile Val 
                85                  90                  95      


Lys Lys Trp Gly Ile Asn Thr Tyr Lys Cys Thr Lys Gln Leu Leu Ser 
            100                 105                 110         


Glu Arg Phe Gly Arg Gly Ser Arg Thr Val Asp Leu Glu Leu Glu Leu 
        115                 120                 125             


Gln Ile Glu Leu Leu Arg Glu Thr Lys Arg Lys Tyr Glu Ser Val Leu 
    130                 135                 140                 


Gln Leu Gly Arg Ala Leu Thr Ala His Leu Tyr Ser Leu Leu Gln Thr 
145                 150                 155                 160 


Gln His Ala Leu Gly Asp Ala Phe Ala Asp Leu Ser Gln Lys Ser Pro 
                165                 170                 175     


Glu Leu Gln Glu Glu Phe Gly Tyr Asn Ala Glu Thr Gln Lys Leu Leu 
            180                 185                 190         


Cys Lys Asn Gly Glu Thr Leu Leu Gly Ala Val Asn Phe Phe Val Ser 
        195                 200                 205             


Ser Ile Asn Thr Leu Val Thr Lys Thr Met Glu Asp Thr Leu Met Thr 
    210                 215                 220                 


Val Lys Gln Tyr Glu Ala Ala Arg Leu Glu Tyr Asp Ala Tyr Arg Thr 
225                 230                 235                 240 


Asp Leu Glu Glu Leu Ser Leu Gly Pro Arg Asp Ala Gly Thr Arg Gly 
                245                 250                 255     


Arg Leu Glu Ser Ala Gln Ala Thr Phe Gln Ala His Arg Asp Lys Tyr 
            260                 265                 270         


Glu Lys Leu Arg Gly Asp Val Ala Ile Lys Leu Lys Phe Leu Glu Glu 
        275                 280                 285             


Asn Lys Ile Lys Val Met His Lys Gln Leu Leu Leu Phe His Asn Ala 
    290                 295                 300                 


Val Ser Ala Tyr Phe Ala Gly Asn Gln Lys Gln Leu Glu Gln Thr Leu 
305                 310                 315                 320 


Gln Gln Phe Asn Ile Lys Leu Arg Pro Pro Gly Ala Glu Lys Pro Ser 
                325                 330                 335     


Trp Leu Glu Glu Gln 
            340     


<210>  1493
<211>  2390
<212>  PRT
<213>  Homo sapiens

<400>  1493

Met Ser Ser Thr Leu Ser Pro Thr Asp Phe Asp Ser Leu Glu Ile Gln 
1               5                   10                  15      


Gly Gln Tyr Ser Asp Ile Asn Asn Arg Trp Asp Leu Pro Asp Ser Asp 
            20                  25                  30          


Trp Asp Asn Asp Ser Ser Ser Ala Arg Leu Phe Glu Arg Ser Arg Ile 
        35                  40                  45              


Lys Ala Leu Ala Asp Glu Arg Glu Ala Val Gln Lys Lys Thr Phe Thr 
    50                  55                  60                  


Lys Trp Val Asn Ser His Leu Ala Arg Val Thr Cys Arg Val Gly Asp 
65                  70                  75                  80  


Leu Tyr Ser Asp Leu Arg Asp Gly Arg Asn Leu Leu Arg Leu Leu Glu 
                85                  90                  95      


Val Leu Ser Gly Glu Ile Leu Pro Lys Pro Thr Lys Gly Arg Met Arg 
            100                 105                 110         


Ile His Cys Leu Glu Asn Val Asp Lys Ala Leu Gln Phe Leu Lys Glu 
        115                 120                 125             


Gln Lys Val His Leu Glu Asn Met Gly Ser His Asp Ile Val Asp Gly 
    130                 135                 140                 


Asn His Arg Leu Thr Leu Gly Leu Val Trp Thr Ile Ile Leu Arg Phe 
145                 150                 155                 160 


Gln Ile Gln Asp Ile Ser Val Glu Thr Glu Asp Asn Lys Glu Lys Lys 
                165                 170                 175     


Ser Ala Lys Asp Ala Leu Leu Leu Trp Cys Gln Met Lys Thr Ala Gly 
            180                 185                 190         


Tyr Pro Asn Val Asn Val His Asn Phe Thr Thr Ser Trp Arg Asp Gly 
        195                 200                 205             


Leu Ala Phe Asn Ala Ile Val His Lys His Arg Pro Asp Leu Leu Asp 
    210                 215                 220                 


Phe Glu Ser Leu Lys Lys Cys Asn Ala His Tyr Asn Leu Gln Asn Ala 
225                 230                 235                 240 


Phe Asn Leu Ala Glu Lys Glu Leu Gly Leu Thr Lys Leu Leu Asp Pro 
                245                 250                 255     


Glu Asp Val Asn Val Asp Gln Pro Asp Glu Lys Ser Ile Ile Thr Tyr 
            260                 265                 270         


Val Ala Thr Tyr Tyr His Tyr Phe Ser Lys Met Lys Ala Leu Ala Val 
        275                 280                 285             


Glu Gly Lys Arg Ile Gly Lys Val Leu Asp His Ala Met Glu Ala Glu 
    290                 295                 300                 


Arg Leu Val Glu Lys Tyr Glu Ser Leu Ala Ser Glu Leu Leu Gln Trp 
305                 310                 315                 320 


Ile Glu Gln Thr Ile Val Thr Leu Asn Asp Arg Gln Leu Ala Asn Ser 
                325                 330                 335     


Leu Ser Gly Val Gln Asn Gln Leu Gln Ser Phe Asn Ser Tyr Arg Thr 
            340                 345                 350         


Val Glu Lys Pro Pro Lys Phe Thr Glu Lys Gly Asn Leu Glu Val Leu 
        355                 360                 365             


Leu Phe Thr Ile Gln Ser Lys Leu Arg Ala Asn Asn Gln Lys Val Tyr 
    370                 375                 380                 


Thr Pro Arg Glu Gly Arg Leu Ile Ser Asp Ile Asn Lys Ala Trp Glu 
385                 390                 395                 400 


Arg Leu Glu Lys Ala Glu His Glu Arg Glu Leu Ala Leu Arg Thr Glu 
                405                 410                 415     


Leu Ile Arg Gln Glu Lys Leu Glu Gln Leu Ala Ala Arg Phe Asp Arg 
            420                 425                 430         


Lys Ala Ala Met Arg Glu Thr Trp Leu Ser Glu Asn Gln Arg Leu Val 
        435                 440                 445             


Ser Gln Asp Asn Phe Gly Leu Glu Leu Ala Ala Val Glu Ala Ala Val 
    450                 455                 460                 


Arg Lys His Glu Ala Ile Glu Thr Asp Ile Val Ala Tyr Ser Gly Arg 
465                 470                 475                 480 


Val Gln Ala Val Asp Ala Val Ala Ala Glu Leu Ala Ala Glu Arg Tyr 
                485                 490                 495     


His Asp Ile Lys Arg Ile Ala Ala Arg Gln His Asn Val Ala Arg Leu 
            500                 505                 510         


Trp Asp Phe Leu Arg Gln Met Val Ala Ala Arg Arg Glu Arg Leu Leu 
        515                 520                 525             


Leu Asn Leu Glu Leu Gln Lys Val Phe Gln Asp Leu Leu Tyr Leu Met 
    530                 535                 540                 


Asp Trp Met Glu Glu Met Lys Gly Arg Leu Gln Ser Gln Asp Leu Gly 
545                 550                 555                 560 


Arg His Leu Ala Gly Val Glu Asp Leu Leu Gln Leu His Glu Leu Val 
                565                 570                 575     


Glu Ala Asp Ile Ala Val Gln Ala Glu Arg Val Arg Ala Val Ser Ala 
            580                 585                 590         


Ser Ala Leu Arg Phe Cys Asn Pro Gly Lys Glu Tyr Arg Pro Cys Asp 
        595                 600                 605             


Pro Gln Leu Val Ser Glu Arg Val Ala Lys Leu Glu Gln Ser Tyr Glu 
    610                 615                 620                 


Ala Leu Cys Glu Leu Ala Ala Ala Arg Arg Ala Arg Leu Glu Glu Ser 
625                 630                 635                 640 


Arg Arg Leu Trp Arg Phe Leu Trp Glu Val Gly Glu Ala Glu Ala Trp 
                645                 650                 655     


Val Arg Glu Gln Gln His Leu Leu Ala Ser Ala Asp Thr Gly Arg Asp 
            660                 665                 670         


Leu Thr Gly Ala Leu Arg Leu Leu Asn Lys His Thr Ala Leu Arg Gly 
        675                 680                 685             


Glu Met Ser Gly Arg Leu Gly Pro Leu Lys Leu Thr Leu Glu Gln Gly 
    690                 695                 700                 


Gln Gln Leu Val Ala Glu Gly His Pro Gly Ala Ser Gln Ala Ser Ala 
705                 710                 715                 720 


Arg Ala Ala Glu Leu Gln Ala Gln Trp Glu Arg Leu Glu Ala Leu Ala 
                725                 730                 735     


Glu Glu Arg Ala Gln Arg Leu Ala Gln Ala Ala Ser Leu Tyr Gln Phe 
            740                 745                 750         


Gln Ala Asp Ala Asn Asp Met Glu Ala Trp Leu Val Asp Ala Leu Arg 
        755                 760                 765             


Leu Val Ser Ser Pro Glu Leu Gly His Asp Glu Phe Ser Thr Gln Ala 
    770                 775                 780                 


Leu Ala Arg Gln His Arg Ala Leu Glu Glu Glu Ile Arg Ser His Arg 
785                 790                 795                 800 


Pro Thr Leu Asp Ala Leu Arg Glu Gln Ala Ala Ala Leu Pro Pro Thr 
                805                 810                 815     


Leu Ser Arg Thr Pro Glu Val Gln Gly Arg Val Pro Thr Leu Glu Arg 
            820                 825                 830         


His Tyr Glu Glu Leu Gln Ala Arg Ala Gly Glu Arg Ala Arg Ala Leu 
        835                 840                 845             


Glu Ala Ala Leu Ala Leu Tyr Thr Met Leu Ser Glu Ala Gly Ala Cys 
    850                 855                 860                 


Gly Leu Trp Val Glu Glu Lys Glu Gln Trp Leu Asn Gly Leu Ala Leu 
865                 870                 875                 880 


Pro Glu Arg Leu Glu Asp Leu Glu Val Val Gln Gln Arg Phe Glu Thr 
                885                 890                 895     


Leu Glu Pro Glu Met Asn Thr Leu Ala Ala Gln Ile Thr Ala Val Asn 
            900                 905                 910         


Asp Ile Ala Glu Gln Leu Leu Lys Ala Asn Pro Pro Gly Lys Asp Arg 
        915                 920                 925             


Ile Val Asn Thr Gln Glu Gln Leu Asn His Arg Trp Gln Gln Phe Arg 
    930                 935                 940                 


Arg Leu Ala Asp Gly Lys Lys Ala Ala Leu Thr Ser Ala Leu Ser Ile 
945                 950                 955                 960 


Gln Asn Tyr His Leu Glu Cys Thr Glu Thr Gln Ala Trp Met Arg Glu 
                965                 970                 975     


Lys Thr Lys Val Ile Glu Ser Thr Gln Gly Leu Gly Asn Asp Leu Ala 
            980                 985                 990         


Gly Val Leu Ala Leu Gln Arg Lys  Leu Ala Gly Thr Glu  Arg Asp Leu 
        995                 1000                 1005             


Glu Ala  Ile Ala Ala Arg Val  Gly Glu Leu Thr Arg  Glu Ala Asn 
    1010                 1015                 1020             


Ala Leu  Ala Ala Gly His Pro  Ala Gln Ala Val Ala  Ile Asn Ala 
    1025                 1030                 1035             


Arg Leu  Arg Glu Val Gln Thr  Gly Trp Glu Asp Leu  Arg Ala Thr 
    1040                 1045                 1050             


Met Arg  Arg Arg Glu Glu Ser  Leu Gly Glu Ala Arg  Arg Leu Gln 
    1055                 1060                 1065             


Asp Phe  Leu Arg Ser Leu Asp  Asp Phe Gln Ala Trp  Leu Gly Arg 
    1070                 1075                 1080             


Thr Gln  Thr Ala Val Ala Ser  Glu Glu Gly Pro Ala  Thr Leu Pro 
    1085                 1090                 1095             


Glu Ala  Glu Ala Leu Leu Ala  Gln His Ala Ala Leu  Arg Gly Glu 
    1100                 1105                 1110             


Val Glu  Arg Ala Gln Ser Glu  Tyr Ser Arg Leu Arg  Ala Leu Gly 
    1115                 1120                 1125             


Glu Glu  Val Thr Arg Asp Gln  Ala Asp Pro Gln Cys  Leu Phe Leu 
    1130                 1135                 1140             


Arg Gln  Arg Leu Glu Ala Leu  Gly Thr Gly Trp Glu  Glu Leu Gly 
    1145                 1150                 1155             


Arg Met  Trp Glu Ser Arg Gln  Gly Arg Leu Ala Gln  Ala His Gly 
    1160                 1165                 1170             


Phe Gln  Gly Phe Leu Arg Asp  Ala Arg Gln Ala Glu  Gly Val Leu 
    1175                 1180                 1185             


Ser Ser  Gln Glu Tyr Val Leu  Ser His Thr Glu Met  Pro Gly Thr 
    1190                 1195                 1200             


Leu Gln  Ala Ala Asp Ala Ala  Ile Lys Lys Leu Glu  Asp Phe Met 
    1205                 1210                 1215             


Ser Thr  Met Asp Ala Asn Gly  Glu Arg Ile His Gly  Leu Leu Glu 
    1220                 1225                 1230             


Ala Gly  Arg Gln Leu Val Ser  Glu Gly Asn Ile His  Ala Asp Lys 
    1235                 1240                 1245             


Ile Arg  Glu Lys Ala Asp Ser  Ile Glu Arg Arg His  Lys Lys Asn 
    1250                 1255                 1260             


Gln Asp  Ala Ala Gln Gln Phe  Leu Gly Arg Leu Arg  Asp Asn Arg 
    1265                 1270                 1275             


Glu Gln  Gln His Phe Leu Gln  Asp Cys His Glu Leu  Lys Leu Trp 
    1280                 1285                 1290             


Ile Asp  Glu Lys Met Leu Thr  Ala Gln Asp Val Ser  Tyr Asp Glu 
    1295                 1300                 1305             


Ala Arg  Asn Leu His Thr Lys  Trp Gln Lys His Gln  Ala Phe Met 
    1310                 1315                 1320             


Ala Glu  Leu Ala Ala Asn Lys  Asp Trp Leu Asp Lys  Val Asp Lys 
    1325                 1330                 1335             


Glu Gly  Arg Glu Leu Thr Leu  Glu Lys Pro Glu Leu  Lys Ala Leu 
    1340                 1345                 1350             


Val Ser  Glu Lys Leu Arg Asp  Leu His Arg Arg Trp  Asp Glu Leu 
    1355                 1360                 1365             


Glu Thr  Thr Thr Gln Ala Lys  Ala Arg Ser Leu Phe  Asp Ala Asn 
    1370                 1375                 1380             


Arg Ala  Glu Leu Phe Ala Gln  Ser Cys Cys Ala Leu  Glu Ser Trp 
    1385                 1390                 1395             


Leu Glu  Ser Leu Gln Ala Gln  Leu His Ser Asp Asp  Tyr Gly Lys 
    1400                 1405                 1410             


Asp Leu  Thr Ser Val Asn Ile  Leu Leu Lys Lys Gln  Gln Met Leu 
    1415                 1420                 1425             


Glu Trp  Glu Met Ala Val Arg  Glu Lys Glu Val Glu  Ala Ile Gln 
    1430                 1435                 1440             


Ala Gln  Ala Lys Ala Leu Ala  Gln Glu Asp Gln Gly  Ala Gly Glu 
    1445                 1450                 1455             


Val Glu  Arg Thr Ser Arg Ala  Val Glu Glu Lys Phe  Arg Ala Leu 
    1460                 1465                 1470             


Cys Gln  Pro Met Arg Glu Arg  Cys Arg Arg Leu Gln  Ala Ser Arg 
    1475                 1480                 1485             


Glu Gln  His Gln Phe His Arg  Asp Val Glu Asp Glu  Ile Leu Trp 
    1490                 1495                 1500             


Val Thr  Glu Arg Leu Pro Met  Ala Ser Ser Met Glu  His Gly Lys 
    1505                 1510                 1515             


Asp Leu  Pro Ser Val Gln Leu  Leu Met Lys Lys Asn  Gln Thr Leu 
    1520                 1525                 1530             


Gln Lys  Glu Ile Gln Gly His  Glu Pro Arg Ile Ala  Asp Leu Arg 
    1535                 1540                 1545             


Glu Arg  Gln Arg Ala Leu Gly  Ala Ala Ala Ala Gly  Pro Glu Leu 
    1550                 1555                 1560             


Ala Glu  Leu Gln Glu Met Trp  Lys Arg Leu Gly His  Glu Leu Glu 
    1565                 1570                 1575             


Leu Arg  Gly Lys Arg Leu Glu  Asp Ala Leu Arg Ala  Gln Gln Phe 
    1580                 1585                 1590             


Tyr Arg  Asp Ala Ala Glu Ala  Glu Ala Trp Met Gly  Glu Gln Glu 
    1595                 1600                 1605             


Leu His  Met Met Gly Gln Glu  Lys Ala Lys Asp Glu  Leu Ser Ala 
    1610                 1615                 1620             


Gln Ala  Glu Val Lys Lys His  Gln Val Leu Glu Gln  Ala Leu Ala 
    1625                 1630                 1635             


Asp Tyr  Ala Gln Thr Ile His  Gln Leu Ala Ala Ser  Ser Gln Asp 
    1640                 1645                 1650             


Met Ile  Asp His Glu His Pro  Glu Ser Thr Arg Ile  Ser Ile Arg 
    1655                 1660                 1665             


Gln Ala  Gln Val Asp Lys Leu  Tyr Ala Gly Leu Lys  Glu Leu Ala 
    1670                 1675                 1680             


Gly Glu  Arg Arg Glu Arg Leu  Gln Glu His Leu Arg  Leu Cys Gln 
    1685                 1690                 1695             


Leu Arg  Arg Glu Leu Asp Asp  Leu Glu Gln Trp Ile  Gln Glu Arg 
    1700                 1705                 1710             


Glu Val  Val Ala Ala Ser His  Glu Leu Gly Gln Asp  Tyr Glu His 
    1715                 1720                 1725             


Val Thr  Met Leu Arg Asp Lys  Phe Arg Glu Phe Ser  Arg Asp Thr 
    1730                 1735                 1740             


Ser Thr  Ile Gly Gln Glu Arg  Val Asp Ser Ala Asn  Ala Leu Ala 
    1745                 1750                 1755             


Asn Gly  Leu Ile Ala Gly Gly  His Ala Ala Arg Ala  Thr Val Ala 
    1760                 1765                 1770             


Glu Trp  Lys Asp Ser Leu Asn  Glu Ala Trp Ala Asp  Leu Leu Glu 
    1775                 1780                 1785             


Leu Leu  Asp Thr Arg Gly Gln  Val Leu Ala Ala Ala  Tyr Glu Leu 
    1790                 1795                 1800             


Gln Arg  Phe Leu His Gly Ala  Arg Gln Ala Leu Ala  Arg Val Gln 
    1805                 1810                 1815             


His Lys  Gln Gln Gln Leu Pro  Asp Gly Thr Gly Arg  Asp Leu Asn 
    1820                 1825                 1830             


Ala Ala  Glu Ala Leu Gln Arg  Arg His Cys Ala Tyr  Glu His Asp 
    1835                 1840                 1845             


Ile Gln  Ala Leu Ser Pro Gln  Val Gln Gln Val Gln  Asp Asp Gly 
    1850                 1855                 1860             


His Arg  Leu Gln Lys Ala Tyr  Ala Gly Asp Lys Ala  Glu Glu Ile 
    1865                 1870                 1875             


Gly Arg  His Met Gln Ala Val  Ala Glu Ala Trp Ala  Gln Leu Gln 
    1880                 1885                 1890             


Gly Ser  Ser Ala Ala Arg Arg  Gln Leu Leu Leu Asp  Thr Thr Asp 
    1895                 1900                 1905             


Lys Phe  Arg Phe Phe Lys Ala  Val Arg Glu Leu Met  Leu Trp Met 
    1910                 1915                 1920             


Asp Glu  Val Asn Leu Gln Met  Asp Ala Gln Glu Arg  Pro Arg Asp 
    1925                 1930                 1935             


Val Ser  Ser Ala Asp Leu Val  Ile Lys Asn Gln Gln  Gly Ile Lys 
    1940                 1945                 1950             


Ala Glu  Ile Glu Ala Arg Ala  Asp Arg Phe Ser Ser  Cys Ile Asp 
    1955                 1960                 1965             


Met Gly  Lys Glu Leu Leu Ala  Arg Ser His Tyr Ala  Ala Glu Glu 
    1970                 1975                 1980             


Ile Ser  Glu Lys Leu Ser Gln  Leu Gln Ala Arg Arg  Gln Glu Thr 
    1985                 1990                 1995             


Ala Glu  Lys Trp Gln Glu Lys  Met Asp Trp Leu Gln  Leu Val Leu 
    2000                 2005                 2010             


Glu Val  Leu Val Phe Gly Arg  Asp Ala Gly Met Ala  Glu Ala Trp 
    2015                 2020                 2025             


Leu Cys  Ser Gln Glu Pro Leu  Val Arg Ser Ala Glu  Leu Gly Cys 
    2030                 2035                 2040             


Thr Val  Asp Glu Val Glu Ser  Leu Ile Lys Arg His  Glu Ala Phe 
    2045                 2050                 2055             


Gln Lys  Ser Ala Val Ala Trp  Glu Glu Arg Phe Cys  Ala Leu Glu 
    2060                 2065                 2070             


Lys Leu  Thr Ala Leu Glu Glu  Arg Glu Lys Glu Arg  Lys Arg Lys 
    2075                 2080                 2085             


Arg Glu  Glu Glu Glu Arg Arg  Lys Gln Pro Pro Ala  Pro Glu Pro 
    2090                 2095                 2100             


Thr Ala  Ser Val Pro Pro Gly  Asp Leu Val Gly Gly  Gln Thr Ala 
    2105                 2110                 2115             


Ser Asp  Thr Thr Trp Asp Gly  Thr Gln Pro Arg Pro  Pro Pro Ser 
    2120                 2125                 2130             


Thr Gln  Ala Pro Ser Val Asn  Gly Val Cys Thr Asp  Gly Glu Pro 
    2135                 2140                 2145             


Ser Gln  Pro Leu Leu Gly Gln  Gln Arg Leu Glu His  Ser Ser Phe 
    2150                 2155                 2160             


Pro Glu  Gly Pro Gly Pro Gly  Ser Gly Asp Glu Ala  Asn Gly Pro 
    2165                 2170                 2175             


Arg Gly  Glu Arg Gln Thr Arg  Thr Arg Gly Pro Ala  Pro Ser Ala 
    2180                 2185                 2190             


Met Pro  Gln Ser Arg Ser Thr  Glu Ser Ala His Ala  Ala Thr Leu 
    2195                 2200                 2205             


Pro Pro  Arg Gly Pro Glu Pro  Ser Ala Gln Glu Gln  Met Glu Gly 
    2210                 2215                 2220             


Met Leu  Cys Arg Lys Gln Glu  Met Glu Ala Phe Gly  Lys Lys Ala 
    2225                 2230                 2235             


Ala Asn  Arg Ser Trp Gln Asn  Val Tyr Cys Val Leu  Arg Arg Gly 
    2240                 2245                 2250             


Ser Leu  Gly Phe Tyr Lys Asp  Ala Lys Ala Ala Ser  Ala Gly Val 
    2255                 2260                 2265             


Pro Tyr  His Gly Glu Val Pro  Val Ser Leu Ala Arg  Ala Gln Gly 
    2270                 2275                 2280             


Ser Val  Ala Phe Asp Tyr Arg  Lys Arg Lys His Val  Phe Lys Leu 
    2285                 2290                 2295             


Gly Leu  Gln Asp Gly Lys Glu  Tyr Leu Phe Gln Ala  Lys Asp Glu 
    2300                 2305                 2310             


Ala Glu  Met Ser Ser Trp Leu  Arg Val Val Asn Ala  Ala Ile Ala 
    2315                 2320                 2325             


Thr Ala  Ser Ser Ala Ser Gly  Glu Pro Glu Glu Pro  Val Val Pro 
    2330                 2335                 2340             


Ser Thr  Thr Arg Gly Met Thr  Arg Ala Met Thr Met  Pro Pro Val 
    2345                 2350                 2355             


Ser Pro  Val Gly Ala Glu Gly  Pro Val Val Leu Arg  Ser Lys Asp 
    2360                 2365                 2370             


Gly Arg  Glu Arg Glu Arg Glu  Lys Arg Phe Ser Phe  Phe Lys Lys 
    2375                 2380                 2385             


Asn Lys  
    2390 


<210>  1494
<211>  504
<212>  PRT
<213>  Homo sapiens

<400>  1494

Met Val Leu Ala Asp Leu Gly Arg Lys Ile Thr Ser Ala Leu Arg Ser 
1               5                   10                  15      


Leu Ser Asn Ala Thr Ile Ile Asn Glu Glu Val Leu Asn Ala Met Leu 
            20                  25                  30          


Lys Glu Val Cys Thr Ala Leu Leu Glu Ala Asp Val Asn Ile Lys Leu 
        35                  40                  45              


Val Lys Gln Leu Arg Glu Asn Val Lys Ser Ala Ile Asp Leu Glu Glu 
    50                  55                  60                  


Met Ala Ser Gly Leu Asn Lys Arg Lys Met Ile Gln His Ala Val Phe 
65                  70                  75                  80  


Lys Glu Leu Val Lys Leu Val Asp Pro Gly Val Lys Ala Trp Thr Pro 
                85                  90                  95      


Thr Lys Gly Lys Gln Asn Val Ile Met Phe Val Gly Leu Gln Gly Ser 
            100                 105                 110         


Gly Lys Thr Thr Thr Cys Ser Lys Leu Ala Tyr Tyr Tyr Gln Arg Lys 
        115                 120                 125             


Gly Trp Lys Thr Cys Leu Ile Cys Ala Asp Thr Phe Arg Ala Gly Ala 
    130                 135                 140                 


Phe Asp Gln Leu Lys Gln Asn Ala Thr Lys Ala Arg Ile Pro Phe Tyr 
145                 150                 155                 160 


Gly Ser Tyr Thr Glu Met Asp Pro Val Ile Ile Ala Ser Glu Gly Val 
                165                 170                 175     


Glu Lys Phe Lys Asn Glu Asn Phe Glu Ile Ile Ile Val Asp Thr Ser 
            180                 185                 190         


Gly Arg His Lys Gln Glu Asp Ser Leu Phe Glu Glu Met Leu Gln Val 
        195                 200                 205             


Ala Asn Ala Ile Gln Pro Asp Asn Ile Val Tyr Val Met Asp Ala Ser 
    210                 215                 220                 


Ile Gly Gln Ala Cys Glu Ala Gln Ala Lys Ala Phe Lys Asp Lys Val 
225                 230                 235                 240 


Asp Val Ala Ser Val Ile Val Thr Lys Leu Asp Gly His Ala Lys Gly 
                245                 250                 255     


Gly Gly Ala Leu Ser Ala Val Ala Ala Thr Lys Ser Pro Ile Ile Phe 
            260                 265                 270         


Ile Gly Thr Gly Glu His Ile Asp Asp Phe Glu Pro Phe Lys Thr Gln 
        275                 280                 285             


Pro Phe Ile Ser Lys Leu Leu Gly Met Gly Asp Ile Glu Gly Leu Ile 
    290                 295                 300                 


Asp Lys Val Asn Glu Leu Lys Leu Asp Asp Asn Glu Ala Leu Ile Glu 
305                 310                 315                 320 


Lys Leu Lys His Gly Gln Phe Thr Leu Arg Asp Met Tyr Glu Gln Phe 
                325                 330                 335     


Gln Asn Ile Met Lys Met Gly Pro Phe Ser Gln Ile Leu Gly Met Ile 
            340                 345                 350         


Pro Gly Phe Gly Thr Asp Phe Met Ser Lys Gly Asn Glu Gln Glu Ser 
        355                 360                 365             


Met Ala Arg Leu Lys Lys Leu Met Thr Ile Met Asp Ser Met Asn Asp 
    370                 375                 380                 


Gln Glu Leu Asp Ser Thr Asp Gly Ala Lys Val Phe Ser Lys Gln Pro 
385                 390                 395                 400 


Gly Arg Ile Gln Arg Val Ala Arg Gly Ser Gly Val Ser Thr Arg Asp 
                405                 410                 415     


Val Gln Glu Leu Leu Thr Gln Tyr Thr Lys Phe Ala Gln Met Val Lys 
            420                 425                 430         


Lys Met Gly Gly Ile Lys Gly Leu Phe Lys Gly Gly Asp Met Ser Lys 
        435                 440                 445             


Asn Val Ser Gln Ser Gln Met Ala Lys Leu Asn Gln Gln Met Ala Lys 
    450                 455                 460                 


Met Met Asp Pro Arg Val Leu His His Met Gly Gly Met Ala Gly Leu 
465                 470                 475                 480 


Gln Ser Met Met Arg Gln Phe Gln Gln Gly Ala Ala Gly Asn Met Lys 
                485                 490                 495     


Gly Met Met Gly Phe Asn Asn Met 
            500                 


<210>  1495
<211>  420
<212>  PRT
<213>  Homo sapiens

<400>  1495

Met Glu Val Pro Pro Arg Leu Ser His Val Pro Pro Pro Leu Phe Pro 
1               5                   10                  15      


Ser Ala Pro Ala Thr Leu Ala Ser Arg Ser Leu Ser His Trp Arg Pro 
            20                  25                  30          


Arg Pro Pro Arg Gln Leu Ala Pro Leu Leu Pro Ser Leu Ala Pro Ser 
        35                  40                  45              


Ser Ala Arg Gln Gly Ala Arg Arg Ala Gln Arg His Val Thr Ala Gln 
    50                  55                  60                  


Gln Pro Ser Arg Leu Ala Gly Gly Ala Ala Ile Lys Gly Gly Arg Arg 
65                  70                  75                  80  


Arg Arg Pro Asp Leu Phe Arg Arg His Phe Lys Ser Ser Ser Ile Gln 
                85                  90                  95      


Arg Ser Ala Ala Ala Ala Ala Ala Thr Arg Thr Ala Arg Gln His Pro 
            100                 105                 110         


Pro Ala Asp Ser Ser Val Thr Met Glu Asp Met Asn Glu Tyr Ser Asn 
        115                 120                 125             


Ile Glu Glu Phe Ala Glu Gly Ser Lys Ile Asn Ala Ser Lys Asn Gln 
    130                 135                 140                 


Gln Asp Asp Gly Lys Met Phe Ile Gly Gly Leu Ser Trp Asp Thr Ser 
145                 150                 155                 160 


Lys Lys Asp Leu Thr Glu Tyr Leu Ser Arg Phe Gly Glu Val Val Asp 
                165                 170                 175     


Cys Thr Ile Lys Thr Asp Pro Val Thr Gly Arg Ser Arg Gly Phe Gly 
            180                 185                 190         


Phe Val Leu Phe Lys Asp Ala Ala Ser Val Asp Lys Val Leu Glu Leu 
        195                 200                 205             


Lys Glu His Lys Leu Asp Gly Lys Leu Ile Asp Pro Lys Arg Ala Lys 
    210                 215                 220                 


Ala Leu Lys Gly Lys Glu Pro Pro Lys Lys Val Phe Val Gly Gly Leu 
225                 230                 235                 240 


Ser Pro Asp Thr Ser Glu Glu Gln Ile Lys Glu Tyr Phe Gly Ala Phe 
                245                 250                 255     


Gly Glu Ile Glu Asn Ile Glu Leu Pro Met Asp Thr Lys Thr Asn Glu 
            260                 265                 270         


Arg Arg Gly Phe Cys Phe Ile Thr Tyr Thr Asp Glu Glu Pro Val Lys 
        275                 280                 285             


Lys Leu Leu Glu Ser Arg Tyr His Gln Ile Gly Ser Gly Lys Cys Glu 
    290                 295                 300                 


Ile Lys Val Ala Gln Pro Lys Glu Val Tyr Arg Gln Gln Gln Gln Gln 
305                 310                 315                 320 


Gln Lys Gly Gly Arg Gly Ala Ala Ala Gly Gly Arg Gly Gly Thr Arg 
                325                 330                 335     


Gly Arg Gly Arg Gly Gln Gly Gln Asn Trp Asn Gln Gly Phe Asn Asn 
            340                 345                 350         


Tyr Tyr Asp Gln Gly Tyr Gly Asn Tyr Asn Ser Ala Tyr Gly Gly Asp 
        355                 360                 365             


Gln Asn Tyr Ser Gly Tyr Gly Gly Tyr Asp Tyr Thr Gly Tyr Asn Tyr 
    370                 375                 380                 


Gly Asn Tyr Gly Tyr Gly Gln Gly Tyr Ala Asp Tyr Ser Gly Gln Gln 
385                 390                 395                 400 


Ser Thr Tyr Gly Lys Ala Ser Arg Gly Gly Gly Asn His Gln Asn Asn 
                405                 410                 415     


Tyr Gln Pro Tyr 
            420 


<210>  1496
<211>  396
<212>  PRT
<213>  Homo sapiens

<400>  1496

Met Phe Leu Lys Ala Val Val Leu Thr Leu Ala Leu Val Ala Val Ala 
1               5                   10                  15      


Gly Ala Arg Ala Glu Val Ser Ala Asp Gln Val Ala Thr Val Met Trp 
            20                  25                  30          


Asp Tyr Phe Ser Gln Leu Ser Asn Asn Ala Lys Glu Ala Val Glu His 
        35                  40                  45              


Leu Gln Lys Ser Glu Leu Thr Gln Gln Leu Asn Ala Leu Phe Gln Asp 
    50                  55                  60                  


Lys Leu Gly Glu Val Asn Thr Tyr Ala Gly Asp Leu Gln Lys Lys Leu 
65                  70                  75                  80  


Val Pro Phe Ala Thr Glu Leu His Glu Arg Leu Ala Lys Asp Ser Glu 
                85                  90                  95      


Lys Leu Lys Glu Glu Ile Gly Lys Glu Leu Glu Glu Leu Arg Ala Arg 
            100                 105                 110         


Leu Leu Pro His Ala Asn Glu Val Ser Gln Lys Ile Gly Asp Asn Leu 
        115                 120                 125             


Arg Glu Leu Gln Gln Arg Leu Glu Pro Tyr Ala Asp Gln Leu Arg Thr 
    130                 135                 140                 


Gln Val Ser Thr Gln Ala Glu Gln Leu Arg Arg Gln Leu Thr Pro Tyr 
145                 150                 155                 160 


Ala Gln Arg Met Glu Arg Val Leu Arg Glu Asn Ala Asp Ser Leu Gln 
                165                 170                 175     


Ala Ser Leu Arg Pro His Ala Asp Glu Leu Lys Ala Lys Ile Asp Gln 
            180                 185                 190         


Asn Val Glu Glu Leu Lys Gly Arg Leu Thr Pro Tyr Ala Asp Glu Phe 
        195                 200                 205             


Lys Val Lys Ile Asp Gln Thr Val Glu Glu Leu Arg Arg Ser Leu Ala 
    210                 215                 220                 


Pro Tyr Ala Gln Asp Thr Gln Glu Lys Leu Asn His Gln Leu Glu Gly 
225                 230                 235                 240 


Leu Thr Phe Gln Met Lys Lys Asn Ala Glu Glu Leu Lys Ala Arg Ile 
                245                 250                 255     


Ser Ala Ser Ala Glu Glu Leu Arg Gln Arg Leu Ala Pro Leu Ala Glu 
            260                 265                 270         


Asp Val Arg Gly Asn Leu Arg Gly Asn Thr Glu Gly Leu Gln Lys Ser 
        275                 280                 285             


Leu Ala Glu Leu Gly Gly His Leu Asp Gln Gln Val Glu Glu Phe Arg 
    290                 295                 300                 


Arg Arg Val Glu Pro Tyr Gly Glu Asn Phe Asn Lys Ala Leu Val Gln 
305                 310                 315                 320 


Gln Met Glu Gln Leu Arg Gln Lys Leu Gly Pro His Ala Gly Asp Val 
                325                 330                 335     


Glu Gly His Leu Ser Phe Leu Glu Lys Asp Leu Arg Asp Lys Val Asn 
            340                 345                 350         


Ser Phe Phe Ser Thr Phe Lys Glu Lys Glu Ser Gln Asp Lys Thr Leu 
        355                 360                 365             


Ser Leu Pro Glu Leu Glu Gln Gln Gln Glu Gln Gln Gln Glu Gln Gln 
    370                 375                 380                 


Gln Glu Gln Val Gln Met Leu Ala Pro Leu Glu Ser 
385                 390                 395     


<210>  1497
<211>  478
<212>  PRT
<213>  Homo sapiens

<400>  1497

Met Gly Arg Cys Cys Phe Tyr Thr Ala Gly Thr Leu Ser Leu Leu Leu 
1               5                   10                  15      


Leu Val Thr Ser Val Thr Leu Leu Val Ala Arg Val Phe Gln Lys Ala 
            20                  25                  30          


Val Asp Gln Ser Ile Glu Lys Lys Ile Val Leu Arg Asn Gly Thr Glu 
        35                  40                  45              


Ala Phe Asp Ser Trp Glu Lys Pro Pro Leu Pro Val Tyr Thr Gln Phe 
    50                  55                  60                  


Tyr Phe Phe Asn Val Thr Asn Pro Glu Glu Ile Leu Arg Gly Glu Thr 
65                  70                  75                  80  


Pro Arg Val Glu Glu Val Gly Pro Tyr Thr Tyr Arg Glu Leu Arg Asn 
                85                  90                  95      


Lys Ala Asn Ile Gln Phe Gly Asp Asn Gly Thr Thr Ile Ser Ala Val 
            100                 105                 110         


Ser Asn Lys Ala Tyr Val Phe Glu Arg Asp Gln Ser Val Gly Asp Pro 
        115                 120                 125             


Lys Ile Asp Leu Ile Arg Thr Leu Asn Ile Pro Val Leu Thr Val Ile 
    130                 135                 140                 


Glu Trp Ser Gln Val His Phe Leu Arg Glu Ile Ile Glu Ala Met Leu 
145                 150                 155                 160 


Lys Ala Tyr Gln Gln Lys Leu Phe Val Thr His Thr Val Asp Glu Leu 
                165                 170                 175     


Leu Trp Gly Tyr Lys Asp Glu Ile Leu Ser Leu Ile His Val Phe Arg 
            180                 185                 190         


Pro Asp Ile Ser Pro Tyr Phe Gly Leu Phe Tyr Glu Lys Asn Gly Thr 
        195                 200                 205             


Asn Asp Gly Asp Tyr Val Phe Leu Thr Gly Glu Asp Ser Tyr Leu Asn 
    210                 215                 220                 


Phe Thr Lys Ile Val Glu Trp Asn Gly Lys Thr Ser Leu Asp Trp Trp 
225                 230                 235                 240 


Ile Thr Asp Lys Cys Asn Met Ile Asn Gly Thr Asp Gly Asp Ser Phe 
                245                 250                 255     


His Pro Leu Ile Thr Lys Asp Glu Val Leu Tyr Val Phe Pro Ser Asp 
            260                 265                 270         


Phe Cys Arg Ser Val Tyr Ile Thr Phe Ser Asp Tyr Glu Ser Val Gln 
        275                 280                 285             


Gly Leu Pro Ala Phe Arg Tyr Lys Val Pro Ala Glu Ile Leu Ala Asn 
    290                 295                 300                 


Thr Ser Asp Asn Ala Gly Phe Cys Ile Pro Glu Gly Asn Cys Leu Gly 
305                 310                 315                 320 


Ser Gly Val Leu Asn Val Ser Ile Cys Lys Asn Gly Ala Pro Ile Ile 
                325                 330                 335     


Met Ser Phe Pro His Phe Tyr Gln Ala Asp Glu Arg Phe Val Ser Ala 
            340                 345                 350         


Ile Glu Gly Met His Pro Asn Gln Glu Asp His Glu Thr Phe Val Asp 
        355                 360                 365             


Ile Asn Pro Leu Thr Gly Ile Ile Leu Lys Ala Ala Lys Arg Phe Gln 
    370                 375                 380                 


Ile Asn Ile Tyr Val Lys Lys Leu Asp Asp Phe Val Glu Thr Gly Asp 
385                 390                 395                 400 


Ile Arg Thr Met Val Phe Pro Val Met Tyr Leu Asn Glu Ser Val His 
                405                 410                 415     


Ile Asp Lys Glu Thr Ala Ser Arg Leu Lys Ser Met Ile Asn Thr Thr 
            420                 425                 430         


Leu Ile Ile Thr Asn Ile Pro Tyr Ile Ile Met Ala Leu Gly Val Phe 
        435                 440                 445             


Phe Gly Leu Val Phe Thr Trp Leu Ala Cys Lys Gly Gln Gly Ser Met 
    450                 455                 460                 


Asp Glu Gly Thr Ala Asp Glu Arg Ala Pro Leu Ile Arg Thr 
465                 470                 475             


<210>  1498
<211>  306
<212>  PRT
<213>  Homo sapiens

<400>  1498

Met Ala Ser Asn Val Thr Asn Lys Thr Asp Pro Arg Ser Met Asn Ser 
1               5                   10                  15      


Arg Val Phe Ile Gly Asn Leu Asn Thr Leu Val Val Lys Lys Ser Asp 
            20                  25                  30          


Val Glu Ala Ile Phe Ser Lys Tyr Gly Lys Ile Val Gly Cys Ser Val 
        35                  40                  45              


His Lys Gly Phe Ala Phe Val Gln Tyr Val Asn Glu Arg Asn Ala Arg 
    50                  55                  60                  


Ala Ala Val Ala Gly Glu Asp Gly Arg Met Ile Ala Gly Gln Val Leu 
65                  70                  75                  80  


Asp Ile Asn Leu Ala Ala Glu Pro Lys Val Asn Arg Gly Lys Ala Gly 
                85                  90                  95      


Val Lys Arg Ser Ala Ala Glu Met Tyr Gly Ser Val Thr Glu His Pro 
            100                 105                 110         


Ser Pro Ser Pro Leu Leu Ser Ser Ser Phe Asp Leu Asp Tyr Asp Phe 
        115                 120                 125             


Gln Arg Asp Tyr Tyr Asp Arg Met Tyr Ser Tyr Pro Ala Arg Val Pro 
    130                 135                 140                 


Pro Pro Pro Pro Ile Ala Arg Ala Val Val Pro Ser Lys Arg Gln Arg 
145                 150                 155                 160 


Val Ser Gly Asn Thr Ser Arg Arg Gly Lys Ser Gly Phe Asn Ser Lys 
                165                 170                 175     


Ser Gly Gln Arg Gly Ser Ser Lys Ser Gly Lys Leu Lys Gly Asp Asp 
            180                 185                 190         


Leu Gln Ala Ile Lys Lys Glu Leu Thr Gln Ile Lys Gln Lys Val Asp 
        195                 200                 205             


Ser Leu Leu Glu Asn Leu Glu Lys Ile Glu Lys Glu Gln Ser Lys Gln 
    210                 215                 220                 


Ala Val Glu Met Lys Asn Asp Lys Ser Glu Glu Glu Gln Ser Ser Ser 
225                 230                 235                 240 


Ser Val Lys Lys Asp Glu Thr Asn Val Lys Met Glu Ser Glu Gly Gly 
                245                 250                 255     


Ala Asp Asp Ser Ala Glu Glu Gly Asp Leu Leu Asp Asp Asp Asp Asn 
            260                 265                 270         


Glu Asp Arg Gly Asp Asp Gln Leu Glu Leu Ile Lys Asp Asp Glu Lys 
        275                 280                 285             


Glu Ala Glu Glu Gly Glu Asp Asp Arg Asp Ser Ala Asn Gly Glu Asp 
    290                 295                 300                 


Asp Ser 
305     


<210>  1499
<211>  415
<212>  PRT
<213>  Homo sapiens

<400>  1499

Met Met Leu Gly Pro Glu Gly Gly Glu Gly Phe Val Val Lys Leu Arg 
1               5                   10                  15      


Gly Leu Pro Trp Ser Cys Ser Val Glu Asp Val Gln Asn Phe Leu Ser 
            20                  25                  30          


Asp Cys Thr Ile His Asp Gly Ala Ala Gly Val His Phe Ile Tyr Thr 
        35                  40                  45              


Arg Glu Gly Arg Gln Ser Gly Glu Ala Phe Val Glu Leu Gly Ser Glu 
    50                  55                  60                  


Asp Asp Val Lys Met Ala Leu Lys Lys Asp Arg Glu Ser Met Gly His 
65                  70                  75                  80  


Arg Tyr Ile Glu Val Phe Lys Ser His Arg Thr Glu Met Asp Trp Val 
                85                  90                  95      


Leu Lys His Ser Gly Pro Asn Ser Ala Asp Ser Ala Asn Asp Gly Phe 
            100                 105                 110         


Val Arg Leu Arg Gly Leu Pro Phe Gly Cys Thr Lys Glu Glu Ile Val 
        115                 120                 125             


Gln Phe Phe Ser Gly Leu Glu Ile Val Pro Asn Gly Ile Thr Leu Pro 
    130                 135                 140                 


Val Asp Pro Glu Gly Lys Ile Thr Gly Glu Ala Phe Val Gln Phe Ala 
145                 150                 155                 160 


Ser Gln Glu Leu Ala Glu Lys Ala Leu Gly Lys His Lys Glu Arg Ile 
                165                 170                 175     


Gly His Arg Tyr Ile Glu Val Phe Lys Ser Ser Gln Glu Glu Val Arg 
            180                 185                 190         


Ser Tyr Ser Asp Pro Pro Leu Lys Phe Met Ser Val Gln Arg Pro Gly 
        195                 200                 205             


Pro Tyr Asp Arg Pro Gly Thr Ala Arg Arg Tyr Ile Gly Ile Val Lys 
    210                 215                 220                 


Gln Ala Gly Leu Glu Arg Met Arg Pro Gly Ala Tyr Ser Thr Gly Tyr 
225                 230                 235                 240 


Gly Gly Tyr Glu Glu Tyr Ser Gly Leu Ser Asp Gly Tyr Gly Phe Thr 
                245                 250                 255     


Thr Asp Leu Phe Gly Arg Asp Leu Ser Tyr Cys Leu Ser Gly Met Tyr 
            260                 265                 270         


Asp His Arg Tyr Gly Asp Ser Glu Phe Thr Val Gln Ser Thr Thr Gly 
        275                 280                 285             


His Cys Val His Met Arg Gly Leu Pro Tyr Lys Ala Thr Glu Asn Asp 
    290                 295                 300                 


Ile Tyr Asn Phe Phe Ser Pro Leu Asn Pro Val Arg Val His Ile Glu 
305                 310                 315                 320 


Ile Gly Pro Asp Gly Arg Val Thr Gly Glu Ala Asp Val Glu Phe Ala 
                325                 330                 335     


Thr His Glu Glu Ala Val Ala Ala Met Ser Lys Asp Arg Ala Asn Met 
            340                 345                 350         


Gln His Arg Tyr Ile Glu Leu Phe Leu Asn Ser Thr Thr Gly Ala Ser 
        355                 360                 365             


Asn Gly Ala Tyr Ser Ser Gln Val Met Gln Gly Met Gly Val Ser Ala 
    370                 375                 380                 


Ala Gln Ala Thr Tyr Ser Gly Leu Glu Ser Gln Ser Val Ser Gly Cys 
385                 390                 395                 400 


Tyr Gly Ala Gly Tyr Ser Gly Gln Asn Ser Met Gly Gly Tyr Asp 
                405                 410                 415 


<210>  1500
<211>  679
<212>  PRT
<213>  Homo sapiens

<400>  1500

Met Ile Ser Ala Ser Arg Ala Ala Ala Ala Arg Leu Val Gly Ala Ala 
1               5                   10                  15      


Ala Ser Arg Gly Pro Thr Ala Ala Arg His Gln Asp Ser Trp Asn Gly 
            20                  25                  30          


Leu Ser His Glu Ala Phe Arg Leu Val Ser Arg Arg Asp Tyr Ala Ser 
        35                  40                  45              


Glu Ala Ile Lys Gly Ala Val Val Gly Ile Asp Leu Gly Thr Thr Asn 
    50                  55                  60                  


Ser Cys Val Ala Val Met Glu Gly Lys Gln Ala Lys Val Leu Glu Asn 
65                  70                  75                  80  


Ala Glu Gly Ala Arg Thr Thr Pro Ser Val Val Ala Phe Thr Ala Asp 
                85                  90                  95      


Gly Glu Arg Leu Val Gly Met Pro Ala Lys Arg Gln Ala Val Thr Asn 
            100                 105                 110         


Pro Asn Asn Thr Phe Tyr Ala Thr Lys Arg Leu Ile Gly Arg Arg Tyr 
        115                 120                 125             


Asp Asp Pro Glu Val Gln Lys Asp Ile Lys Asn Val Pro Phe Lys Ile 
    130                 135                 140                 


Val Arg Ala Ser Asn Gly Asp Ala Trp Val Glu Ala His Gly Lys Leu 
145                 150                 155                 160 


Tyr Ser Pro Ser Gln Ile Gly Ala Phe Val Leu Met Lys Met Lys Glu 
                165                 170                 175     


Thr Ala Glu Asn Tyr Leu Gly His Thr Ala Lys Asn Ala Val Ile Thr 
            180                 185                 190         


Val Pro Ala Tyr Phe Asn Asp Ser Gln Arg Gln Ala Thr Lys Asp Ala 
        195                 200                 205             


Gly Gln Ile Ser Gly Leu Asn Val Leu Arg Val Ile Asn Glu Pro Thr 
    210                 215                 220                 


Ala Ala Ala Leu Ala Tyr Gly Leu Asp Lys Ser Glu Asp Lys Val Ile 
225                 230                 235                 240 


Ala Val Tyr Asp Leu Gly Gly Gly Thr Phe Asp Ile Ser Ile Leu Glu 
                245                 250                 255     


Ile Gln Lys Gly Val Phe Glu Val Lys Ser Thr Asn Gly Asp Thr Phe 
            260                 265                 270         


Leu Gly Gly Glu Asp Phe Asp Gln Ala Leu Leu Arg His Ile Val Lys 
        275                 280                 285             


Glu Phe Lys Arg Glu Thr Gly Val Asp Leu Thr Lys Asp Asn Met Ala 
    290                 295                 300                 


Leu Gln Arg Val Arg Glu Ala Ala Glu Lys Ala Lys Cys Glu Leu Ser 
305                 310                 315                 320 


Ser Ser Val Gln Thr Asp Ile Asn Leu Pro Tyr Leu Thr Met Asp Ser 
                325                 330                 335     


Ser Gly Pro Lys His Leu Asn Met Lys Leu Thr Arg Ala Gln Phe Glu 
            340                 345                 350         


Gly Ile Val Thr Asp Leu Ile Arg Arg Thr Ile Ala Pro Cys Gln Lys 
        355                 360                 365             


Ala Met Gln Asp Ala Glu Val Ser Lys Ser Asp Ile Gly Glu Val Ile 
    370                 375                 380                 


Leu Val Gly Gly Met Thr Arg Met Pro Lys Val Gln Gln Thr Val Gln 
385                 390                 395                 400 


Asp Leu Phe Gly Arg Ala Pro Ser Lys Ala Val Asn Pro Asp Glu Ala 
                405                 410                 415     


Val Ala Ile Gly Ala Ala Ile Gln Gly Gly Val Leu Ala Gly Asp Val 
            420                 425                 430         


Thr Asp Val Leu Leu Leu Asp Val Thr Pro Leu Ser Leu Gly Ile Glu 
        435                 440                 445             


Thr Leu Gly Gly Val Phe Thr Lys Leu Ile Asn Arg Asn Thr Thr Ile 
    450                 455                 460                 


Pro Thr Lys Lys Ser Gln Val Phe Ser Thr Ala Ala Asp Gly Gln Thr 
465                 470                 475                 480 


Gln Val Glu Ile Lys Val Cys Gln Gly Glu Arg Glu Met Ala Gly Asp 
                485                 490                 495     


Asn Lys Leu Leu Gly Gln Phe Thr Leu Ile Gly Ile Pro Pro Ala Pro 
            500                 505                 510         


Arg Gly Val Pro Gln Ile Glu Val Thr Phe Asp Ile Asp Ala Asn Gly 
        515                 520                 525             


Ile Val His Val Ser Ala Lys Asp Lys Gly Thr Gly Arg Glu Gln Gln 
    530                 535                 540                 


Ile Val Ile Gln Ser Ser Gly Gly Leu Ser Lys Asp Asp Ile Glu Asn 
545                 550                 555                 560 


Met Val Lys Asn Ala Glu Lys Tyr Ala Glu Glu Asp Arg Arg Lys Lys 
                565                 570                 575     


Glu Arg Val Glu Ala Val Asn Met Ala Glu Gly Ile Ile His Asp Thr 
            580                 585                 590         


Glu Thr Lys Met Glu Glu Phe Lys Asp Gln Leu Pro Ala Asp Glu Cys 
        595                 600                 605             


Asn Lys Leu Lys Glu Glu Ile Ser Lys Met Arg Glu Leu Leu Ala Arg 
    610                 615                 620                 


Lys Asp Ser Glu Thr Gly Glu Asn Ile Arg Gln Ala Ala Ser Ser Leu 
625                 630                 635                 640 


Gln Gln Ala Ser Leu Lys Leu Phe Glu Met Ala Tyr Lys Lys Met Ala 
                645                 650                 655     


Ser Glu Arg Glu Gly Ser Gly Ser Ser Gly Thr Gly Glu Gln Lys Glu 
            660                 665                 670         


Asp Gln Lys Glu Glu Lys Gln 
        675                 


<210>  1501
<211>  195
<212>  PRT
<213>  Homo sapiens

<400>  1501

Met Ala Leu Leu Phe Pro Leu Leu Ala Ala Leu Val Met Thr Ser Tyr 
1               5                   10                  15      


Ser Pro Val Gly Ser Leu Gly Cys Asp Leu Pro Gln Asn His Gly Leu 
            20                  25                  30          


Leu Ser Arg Asn Thr Leu Val Leu Leu His Gln Met Arg Arg Ile Ser 
        35                  40                  45              


Pro Phe Leu Cys Leu Lys Asp Arg Arg Asp Phe Arg Phe Pro Gln Glu 
    50                  55                  60                  


Met Val Lys Gly Ser Gln Leu Gln Lys Ala His Val Met Ser Val Leu 
65                  70                  75                  80  


His Glu Met Leu Gln Gln Ile Phe Ser Leu Phe His Thr Glu Arg Ser 
                85                  90                  95      


Ser Ala Ala Trp Asn Met Thr Leu Leu Asp Gln Leu His Thr Gly Leu 
            100                 105                 110         


His Gln Gln Leu Gln His Leu Glu Thr Cys Leu Leu Gln Val Val Gly 
        115                 120                 125             


Glu Gly Glu Ser Ala Gly Ala Ile Ser Ser Pro Ala Leu Thr Leu Arg 
    130                 135                 140                 


Arg Tyr Phe Gln Gly Ile Arg Val Tyr Leu Lys Glu Lys Lys Tyr Ser 
145                 150                 155                 160 


Asp Cys Ala Trp Glu Val Val Arg Met Glu Ile Met Lys Ser Leu Phe 
                165                 170                 175     


Leu Ser Thr Asn Met Gln Glu Arg Leu Arg Ser Lys Asp Arg Asp Leu 
            180                 185                 190         


Gly Ser Ser 
        195 


<210>  1502
<211>  963
<212>  PRT
<213>  Homo sapiens

<400>  1502

Met Ala Asp Leu Ala Glu Cys Asn Ile Lys Val Met Cys Arg Phe Arg 
1               5                   10                  15      


Pro Leu Asn Glu Ser Glu Val Asn Arg Gly Asp Lys Tyr Ile Ala Lys 
            20                  25                  30          


Phe Gln Gly Glu Asp Thr Val Val Ile Ala Ser Lys Pro Tyr Ala Phe 
        35                  40                  45              


Asp Arg Val Phe Gln Ser Ser Thr Ser Gln Glu Gln Val Tyr Asn Asp 
    50                  55                  60                  


Cys Ala Lys Lys Ile Val Lys Asp Val Leu Glu Gly Tyr Asn Gly Thr 
65                  70                  75                  80  


Ile Phe Ala Tyr Gly Gln Thr Ser Ser Gly Lys Thr His Thr Met Glu 
                85                  90                  95      


Gly Lys Leu His Asp Pro Glu Gly Met Gly Ile Ile Pro Arg Ile Val 
            100                 105                 110         


Gln Asp Ile Phe Asn Tyr Ile Tyr Ser Met Asp Glu Asn Leu Glu Phe 
        115                 120                 125             


His Ile Lys Val Ser Tyr Phe Glu Ile Tyr Leu Asp Lys Ile Arg Asp 
    130                 135                 140                 


Leu Leu Asp Val Ser Lys Thr Asn Leu Ser Val His Glu Asp Lys Asn 
145                 150                 155                 160 


Arg Val Pro Tyr Val Lys Gly Cys Thr Glu Arg Phe Val Cys Ser Pro 
                165                 170                 175     


Asp Glu Val Met Asp Thr Ile Asp Glu Gly Lys Ser Asn Arg His Val 
            180                 185                 190         


Ala Val Thr Asn Met Asn Glu His Ser Ser Arg Ser His Ser Ile Phe 
        195                 200                 205             


Leu Ile Asn Val Lys Gln Glu Asn Thr Gln Thr Glu Gln Lys Leu Ser 
    210                 215                 220                 


Gly Lys Leu Tyr Leu Val Asp Leu Ala Gly Ser Glu Lys Val Ser Lys 
225                 230                 235                 240 


Thr Gly Ala Glu Gly Ala Val Leu Asp Glu Ala Lys Asn Ile Asn Lys 
                245                 250                 255     


Ser Leu Ser Ala Leu Gly Asn Val Ile Ser Ala Leu Ala Glu Gly Ser 
            260                 265                 270         


Thr Tyr Val Pro Tyr Arg Asp Ser Lys Met Thr Arg Ile Leu Gln Asp 
        275                 280                 285             


Ser Leu Gly Gly Asn Cys Arg Thr Thr Ile Val Ile Cys Cys Ser Pro 
    290                 295                 300                 


Ser Ser Tyr Asn Glu Ser Glu Thr Lys Ser Thr Leu Leu Phe Gly Gln 
305                 310                 315                 320 


Arg Ala Lys Thr Ile Lys Asn Thr Val Cys Val Asn Val Glu Leu Thr 
                325                 330                 335     


Ala Glu Gln Trp Lys Lys Lys Tyr Glu Lys Glu Lys Glu Lys Asn Lys 
            340                 345                 350         


Ile Leu Arg Asn Thr Ile Gln Trp Leu Glu Asn Glu Leu Asn Arg Trp 
        355                 360                 365             


Arg Asn Gly Glu Thr Val Pro Ile Asp Glu Gln Phe Asp Lys Glu Lys 
    370                 375                 380                 


Ala Asn Leu Glu Ala Phe Thr Val Asp Lys Asp Ile Thr Leu Thr Asn 
385                 390                 395                 400 


Asp Lys Pro Ala Thr Ala Ile Gly Val Ile Gly Asn Phe Thr Asp Ala 
                405                 410                 415     


Glu Arg Arg Lys Cys Glu Glu Glu Ile Ala Lys Leu Tyr Lys Gln Leu 
            420                 425                 430         


Asp Asp Lys Asp Glu Glu Ile Asn Gln Gln Ser Gln Leu Val Glu Lys 
        435                 440                 445             


Leu Lys Thr Gln Met Leu Asp Gln Glu Glu Leu Leu Ala Ser Thr Arg 
    450                 455                 460                 


Arg Asp Gln Asp Asn Met Gln Ala Glu Leu Asn Arg Leu Gln Ala Glu 
465                 470                 475                 480 


Asn Asp Ala Ser Lys Glu Glu Val Lys Glu Val Leu Gln Ala Leu Glu 
                485                 490                 495     


Glu Leu Ala Val Asn Tyr Asp Gln Lys Ser Gln Glu Val Glu Asp Lys 
            500                 505                 510         


Thr Lys Glu Tyr Glu Leu Leu Ser Asp Glu Leu Asn Gln Lys Ser Ala 
        515                 520                 525             


Thr Leu Ala Ser Ile Asp Ala Glu Leu Gln Lys Leu Lys Glu Met Thr 
    530                 535                 540                 


Asn His Gln Lys Lys Arg Ala Ala Glu Met Met Ala Ser Leu Leu Lys 
545                 550                 555                 560 


Asp Leu Ala Glu Ile Gly Ile Ala Val Gly Asn Asn Asp Val Lys Gln 
                565                 570                 575     


Pro Glu Gly Thr Gly Met Ile Asp Glu Glu Phe Thr Val Ala Arg Leu 
            580                 585                 590         


Tyr Ile Ser Lys Met Lys Ser Glu Val Lys Thr Met Val Lys Arg Cys 
        595                 600                 605             


Lys Gln Leu Glu Ser Thr Gln Thr Glu Ser Asn Lys Lys Met Glu Glu 
    610                 615                 620                 


Asn Glu Lys Glu Leu Ala Ala Cys Gln Leu Arg Ile Ser Gln His Glu 
625                 630                 635                 640 


Ala Lys Ile Lys Ser Leu Thr Glu Tyr Leu Gln Asn Val Glu Gln Lys 
                645                 650                 655     


Lys Arg Gln Leu Glu Glu Ser Val Asp Ala Leu Ser Glu Glu Leu Val 
            660                 665                 670         


Gln Leu Arg Ala Gln Glu Lys Val His Glu Met Glu Lys Glu His Leu 
        675                 680                 685             


Asn Lys Val Gln Thr Ala Asn Glu Val Lys Gln Ala Val Glu Gln Gln 
    690                 695                 700                 


Ile Gln Ser His Arg Glu Thr His Gln Lys Gln Ile Ser Ser Leu Arg 
705                 710                 715                 720 


Asp Glu Val Glu Ala Lys Ala Lys Leu Ile Thr Asp Leu Gln Asp Gln 
                725                 730                 735     


Asn Gln Lys Met Met Leu Glu Gln Glu Arg Leu Arg Val Glu His Glu 
            740                 745                 750         


Lys Leu Lys Ala Thr Asp Gln Glu Lys Ser Arg Lys Leu His Glu Leu 
        755                 760                 765             


Thr Val Met Gln Asp Arg Arg Glu Gln Ala Arg Gln Asp Leu Lys Gly 
    770                 775                 780                 


Leu Glu Glu Thr Val Ala Lys Glu Leu Gln Thr Leu His Asn Leu Arg 
785                 790                 795                 800 


Lys Leu Phe Val Gln Asp Leu Ala Thr Arg Val Lys Lys Ser Ala Glu 
                805                 810                 815     


Ile Asp Ser Asp Asp Thr Gly Gly Ser Ala Ala Gln Lys Gln Lys Ile 
            820                 825                 830         


Ser Phe Leu Glu Asn Asn Leu Glu Gln Leu Thr Lys Val His Lys Gln 
        835                 840                 845             


Leu Val Arg Asp Asn Ala Asp Leu Arg Cys Glu Leu Pro Lys Leu Glu 
    850                 855                 860                 


Lys Arg Leu Arg Ala Thr Ala Glu Arg Val Lys Ala Leu Glu Ser Ala 
865                 870                 875                 880 


Leu Lys Glu Ala Lys Glu Asn Ala Ser Arg Asp Arg Lys Arg Tyr Gln 
                885                 890                 895     


Gln Glu Val Asp Arg Ile Lys Glu Ala Val Arg Ser Lys Asn Met Ala 
            900                 905                 910         


Arg Arg Gly His Ser Ala Gln Ile Ala Lys Pro Ile Arg Pro Gly Gln 
        915                 920                 925             


His Pro Ala Ala Ser Pro Thr His Pro Ser Ala Ile Arg Gly Gly Gly 
    930                 935                 940                 


Ala Phe Val Gln Asn Ser Gln Pro Val Ala Val Arg Gly Gly Gly Gly 
945                 950                 955                 960 


Lys Gln Val 
            


<210>  1503
<211>  356
<212>  PRT
<213>  Homo sapiens

<400>  1503

Met Ser Arg Pro Leu Leu Ile Thr Phe Thr Pro Ala Thr Asp Pro Ser 
1               5                   10                  15      


Asp Leu Trp Lys Asp Gly Gln Gln Gln Pro Gln Pro Glu Lys Pro Glu 
            20                  25                  30          


Ser Thr Leu Asp Gly Ala Ala Ala Arg Ala Phe Tyr Glu Ala Leu Ile 
        35                  40                  45              


Gly Asp Glu Ser Ser Ala Pro Asp Ser Gln Arg Ser Gln Thr Glu Pro 
    50                  55                  60                  


Ala Arg Glu Arg Lys Arg Lys Lys Arg Arg Ile Met Lys Ala Pro Ala 
65                  70                  75                  80  


Ala Glu Ala Val Ala Glu Gly Ala Ser Gly Arg His Gly Gln Gly Arg 
                85                  90                  95      


Ser Leu Glu Ala Glu Asp Lys Met Thr His Arg Ile Leu Arg Ala Ala 
            100                 105                 110         


Gln Glu Gly Asp Leu Pro Glu Leu Arg Arg Leu Leu Glu Pro His Glu 
        115                 120                 125             


Ala Gly Gly Ala Gly Gly Asn Ile Asn Ala Arg Asp Ala Phe Trp Trp 
    130                 135                 140                 


Thr Pro Leu Met Cys Ala Ala Arg Ala Gly Gln Gly Ala Ala Val Ser 
145                 150                 155                 160 


Tyr Leu Leu Gly Arg Gly Ala Ala Trp Val Gly Val Cys Glu Leu Ser 
                165                 170                 175     


Gly Arg Asp Ala Ala Gln Leu Ala Glu Glu Ala Gly Phe Pro Glu Val 
            180                 185                 190         


Ala Arg Met Val Arg Glu Ser His Gly Glu Thr Arg Ser Pro Glu Asn 
        195                 200                 205             


Arg Ser Pro Thr Pro Ser Leu Gln Tyr Cys Glu Asn Cys Asp Thr His 
    210                 215                 220                 


Phe Gln Asp Ser Asn His Arg Thr Ser Thr Ala His Leu Leu Ser Leu 
225                 230                 235                 240 


Ser Gln Gly Pro Gln Pro Pro Asn Leu Pro Leu Gly Val Pro Ile Ser 
                245                 250                 255     


Ser Pro Gly Phe Lys Leu Leu Leu Arg Gly Gly Trp Glu Pro Gly Met 
            260                 265                 270         


Gly Leu Gly Pro Arg Gly Glu Gly Arg Ala Asn Pro Ile Pro Thr Val 
        275                 280                 285             


Leu Lys Arg Asp Gln Glu Gly Leu Gly Tyr Arg Ser Ala Pro Gln Pro 
    290                 295                 300                 


Arg Val Thr His Phe Pro Ala Trp Asp Thr Arg Ala Val Ala Gly Arg 
305                 310                 315                 320 


Glu Arg Pro Pro Arg Val Ala Thr Leu Ser Trp Arg Glu Glu Arg Arg 
                325                 330                 335     


Arg Glu Glu Lys Asp Arg Ala Trp Glu Arg Asp Leu Arg Thr Tyr Met 
            340                 345                 350         


Asn Leu Glu Phe 
        355     


<210>  1504
<211>  130
<212>  PRT
<213>  Homo sapiens

<400>  1504

Met Ser Gly Arg Gly Lys Gln Gly Gly Lys Ala Arg Ala Lys Ala Lys 
1               5                   10                  15      


Ser Arg Ser Ser Arg Ala Gly Leu Gln Phe Pro Val Gly Arg Val His 
            20                  25                  30          


Arg Leu Leu Arg Lys Gly Asn Tyr Ala Glu Arg Val Gly Ala Gly Ala 
        35                  40                  45              


Pro Val Tyr Met Ala Ala Val Leu Glu Tyr Leu Thr Ala Glu Ile Leu 
    50                  55                  60                  


Glu Leu Ala Gly Asn Ala Ala Arg Asp Asn Lys Lys Thr Arg Ile Ile 
65                  70                  75                  80  


Pro Arg His Leu Gln Leu Ala Ile Arg Asn Asp Glu Glu Leu Asn Lys 
                85                  90                  95      


Leu Leu Gly Lys Val Thr Ile Ala Gln Gly Gly Val Leu Pro Asn Ile 
            100                 105                 110         


Gln Ala Val Leu Leu Pro Lys Lys Thr Glu Ser His His Lys Ala Lys 
        115                 120                 125             


Gly Lys 
    130 


<210>  1505
<211>  438
<212>  PRT
<213>  Homo sapiens

<400>  1505

Met Ala Ala Gly Leu Arg Lys Arg Gly Arg Ser Gly Ser Ala Ala Gln 
1               5                   10                  15      


Ala Glu Gly Leu Cys Lys Gln Trp Leu Gln Arg Ala Trp Gln Glu Arg 
            20                  25                  30          


Arg Leu Leu Leu Arg Glu Pro Arg Tyr Thr Leu Leu Val Ala Ala Cys 
        35                  40                  45              


Leu Cys Leu Ala Glu Val Gly Ile Thr Phe Trp Val Ile His Arg Val 
    50                  55                  60                  


Ala Tyr Thr Glu Ile Asp Trp Lys Ala Tyr Met Ala Glu Val Glu Gly 
65                  70                  75                  80  


Val Ile Asn Gly Thr Tyr Asp Tyr Thr Gln Leu Gln Gly Asp Thr Gly 
                85                  90                  95      


Pro Leu Val Tyr Pro Ala Gly Phe Val Tyr Ile Phe Met Gly Leu Tyr 
            100                 105                 110         


Tyr Ala Thr Ser Arg Gly Thr Asp Ile Arg Met Ala Gln Asn Ile Phe 
        115                 120                 125             


Ala Val Leu Tyr Leu Ala Thr Leu Leu Leu Val Phe Leu Ile Tyr His 
    130                 135                 140                 


Gln Thr Cys Lys Val Pro Pro Phe Val Phe Phe Phe Met Cys Cys Ala 
145                 150                 155                 160 


Ser Tyr Arg Val His Ser Ile Phe Val Leu Arg Leu Phe Asn Asp Pro 
                165                 170                 175     


Val Ala Met Val Leu Leu Phe Leu Ser Ile Asn Leu Leu Leu Ala Gln 
            180                 185                 190         


Arg Trp Gly Trp Gly Cys Cys Phe Phe Ser Leu Ala Val Ser Val Lys 
        195                 200                 205             


Met Asn Val Leu Leu Phe Ala Pro Gly Leu Leu Phe Leu Leu Leu Thr 
    210                 215                 220                 


Gln Phe Gly Phe Arg Gly Ala Leu Pro Lys Leu Gly Ile Cys Ala Gly 
225                 230                 235                 240 


Leu Gln Val Val Leu Gly Leu Pro Phe Leu Leu Glu Asn Pro Ser Gly 
                245                 250                 255     


Tyr Leu Ser Arg Ser Phe Asp Leu Gly Arg Gln Phe Leu Phe His Trp 
            260                 265                 270         


Thr Val Asn Trp Arg Phe Leu Pro Glu Ala Leu Phe Leu His Arg Ala 
        275                 280                 285             


Phe His Leu Ala Leu Leu Thr Ala His Leu Thr Leu Leu Leu Leu Phe 
    290                 295                 300                 


Ala Leu Cys Arg Trp His Arg Thr Gly Glu Ser Ile Leu Ser Leu Leu 
305                 310                 315                 320 


Arg Asp Pro Ser Lys Arg Lys Val Pro Pro Gln Pro Leu Thr Pro Asn 
                325                 330                 335     


Gln Ile Val Ser Thr Leu Phe Thr Ser Asn Phe Ile Gly Ile Cys Phe 
            340                 345                 350         


Ser Arg Ser Leu His Tyr Gln Phe Tyr Val Trp Tyr Phe His Thr Leu 
        355                 360                 365             


Pro Tyr Leu Leu Trp Ala Met Pro Ala Arg Trp Leu Thr His Leu Leu 
    370                 375                 380                 


Arg Leu Leu Val Leu Gly Leu Ile Glu Leu Ser Trp Asn Thr Tyr Pro 
385                 390                 395                 400 


Ser Thr Ser Cys Ser Ser Ala Ala Leu His Ile Cys His Ala Val Ile 
                405                 410                 415     


Leu Leu Gln Leu Trp Leu Gly Pro Gln Pro Phe Pro Lys Ser Thr Gln 
            420                 425                 430         


His Ser Lys Lys Ala His 
        435             


<210>  1506
<211>  824
<212>  PRT
<213>  Homo sapiens

<400>  1506

Met Ser Ala Pro Ser Glu Glu Glu Glu Tyr Ala Arg Leu Val Met Glu 
1               5                   10                  15      


Ala Gln Pro Glu Trp Leu Arg Ala Glu Val Lys Arg Leu Ser His Glu 
            20                  25                  30          


Leu Ala Glu Thr Thr Arg Glu Lys Ile Gln Ala Ala Glu Tyr Gly Leu 
        35                  40                  45              


Ala Val Leu Glu Glu Lys His Gln Leu Lys Leu Gln Phe Glu Glu Leu 
    50                  55                  60                  


Glu Val Asp Tyr Glu Ala Ile Arg Ser Glu Met Glu Gln Leu Lys Glu 
65                  70                  75                  80  


Ala Phe Gly Gln Ala His Thr Asn His Lys Lys Val Ala Ala Asp Gly 
                85                  90                  95      


Glu Ser Arg Glu Glu Ser Leu Ile Gln Glu Ser Ala Ser Lys Glu Gln 
            100                 105                 110         


Tyr Tyr Val Arg Lys Val Leu Glu Leu Gln Thr Glu Leu Lys Gln Leu 
        115                 120                 125             


Arg Asn Val Leu Thr Asn Thr Gln Ser Glu Asn Glu Arg Leu Ala Ser 
    130                 135                 140                 


Val Ala Gln Glu Leu Lys Glu Ile Asn Gln Asn Val Glu Ile Gln Arg 
145                 150                 155                 160 


Gly Arg Leu Arg Asp Asp Ile Lys Glu Tyr Lys Phe Arg Glu Ala Arg 
                165                 170                 175     


Leu Leu Gln Asp Tyr Ser Glu Leu Glu Glu Glu Asn Ile Ser Leu Gln 
            180                 185                 190         


Lys Gln Val Ser Val Leu Arg Gln Asn Gln Val Glu Phe Glu Gly Leu 
        195                 200                 205             


Lys His Glu Ile Lys Arg Leu Glu Glu Glu Thr Glu Tyr Leu Asn Ser 
    210                 215                 220                 


Gln Leu Glu Asp Ala Ile Arg Leu Lys Glu Ile Ser Glu Arg Gln Leu 
225                 230                 235                 240 


Glu Glu Ala Leu Glu Thr Leu Lys Thr Glu Arg Glu Gln Lys Asn Ser 
                245                 250                 255     


Leu Arg Lys Glu Leu Ser His Tyr Met Ser Ile Asn Asp Ser Phe Tyr 
            260                 265                 270         


Thr Ser His Leu His Val Ser Leu Asp Gly Leu Lys Phe Ser Asp Asp 
        275                 280                 285             


Ala Ala Glu Pro Asn Asn Asp Ala Glu Ala Leu Val Asn Gly Phe Glu 
    290                 295                 300                 


His Gly Gly Leu Ala Lys Leu Pro Leu Asp Asn Lys Thr Ser Thr Pro 
305                 310                 315                 320 


Lys Lys Glu Gly Leu Ala Pro Pro Ser Pro Ser Leu Val Ser Asp Leu 
                325                 330                 335     


Leu Ser Glu Leu Asn Ile Ser Glu Ile Gln Lys Leu Lys Gln Gln Leu 
            340                 345                 350         


Met Gln Met Glu Arg Glu Lys Ala Gly Leu Leu Ala Thr Leu Gln Asp 
        355                 360                 365             


Thr Gln Lys Gln Leu Glu His Thr Arg Gly Ser Leu Ser Glu Gln Gln 
    370                 375                 380                 


Glu Lys Val Thr Arg Leu Thr Glu Asn Leu Ser Ala Leu Arg Arg Leu 
385                 390                 395                 400 


Gln Ala Ser Lys Glu Arg Gln Thr Ala Leu Asp Asn Glu Lys Asp Arg 
                405                 410                 415     


Asp Ser His Glu Asp Gly Asp Tyr Tyr Glu Val Asp Ile Asn Gly Pro 
            420                 425                 430         


Glu Ile Leu Ala Cys Lys Tyr His Val Ala Val Ala Glu Ala Gly Glu 
        435                 440                 445             


Leu Arg Glu Gln Leu Lys Ala Leu Arg Ser Thr His Glu Ala Arg Glu 
    450                 455                 460                 


Ala Gln His Ala Glu Glu Lys Gly Arg Tyr Glu Ala Glu Gly Gln Ala 
465                 470                 475                 480 


Leu Thr Glu Lys Val Ser Leu Leu Glu Lys Ala Ser Arg Gln Asp Arg 
                485                 490                 495     


Glu Leu Leu Ala Arg Leu Glu Lys Glu Leu Lys Lys Val Ser Asp Val 
            500                 505                 510         


Ala Gly Glu Thr Gln Gly Ser Leu Ser Val Ala Gln Asp Glu Leu Val 
        515                 520                 525             


Thr Phe Ser Glu Glu Leu Ala Asn Leu Tyr His His Val Cys Met Cys 
    530                 535                 540                 


Asn Asn Glu Thr Pro Asn Arg Val Met Leu Asp Tyr Tyr Arg Glu Gly 
545                 550                 555                 560 


Gln Gly Gly Ala Gly Arg Thr Ser Pro Gly Gly Arg Thr Ser Pro Glu 
                565                 570                 575     


Ala Arg Gly Arg Arg Ser Pro Ile Leu Leu Pro Lys Gly Leu Leu Ala 
            580                 585                 590         


Pro Glu Ala Gly Arg Ala Asp Gly Gly Thr Gly Asp Ser Ser Pro Ser 
        595                 600                 605             


Pro Gly Ser Ser Leu Pro Ser Pro Leu Ser Asp Pro Arg Arg Glu Pro 
    610                 615                 620                 


Met Asn Ile Tyr Asn Leu Ile Ala Ile Ile Arg Asp Gln Ile Lys His 
625                 630                 635                 640 


Leu Gln Ala Ala Val Asp Arg Thr Thr Glu Leu Ser Arg Gln Arg Ile 
                645                 650                 655     


Ala Ser Gln Glu Leu Gly Pro Ala Val Asp Lys Asp Lys Glu Ala Leu 
            660                 665                 670         


Met Glu Glu Ile Leu Lys Leu Lys Ser Leu Leu Ser Thr Lys Arg Glu 
        675                 680                 685             


Gln Ile Thr Thr Leu Arg Thr Val Leu Lys Ala Asn Lys Gln Thr Ala 
    690                 695                 700                 


Glu Val Ala Leu Ala Asn Leu Lys Ser Lys Tyr Glu Asn Glu Lys Ala 
705                 710                 715                 720 


Met Val Thr Glu Thr Met Met Lys Leu Arg Asn Glu Leu Lys Ala Leu 
                725                 730                 735     


Lys Glu Asp Ala Ala Thr Phe Ser Ser Leu Arg Ala Met Phe Ala Thr 
            740                 745                 750         


Arg Cys Asp Glu Tyr Ile Thr Gln Leu Asp Glu Met Gln Arg Gln Leu 
        755                 760                 765             


Ala Ala Ala Glu Asp Glu Lys Lys Thr Leu Asn Ser Leu Leu Arg Met 
    770                 775                 780                 


Ala Ile Gln Gln Lys Leu Ala Leu Thr Gln Arg Leu Glu Leu Leu Glu 
785                 790                 795                 800 


Leu Asp His Glu Gln Thr Arg Arg Gly Arg Ala Lys Ala Ala Pro Lys 
                805                 810                 815     


Thr Lys Pro Ala Thr Pro Ser Leu 
            820                 


<210>  1507
<211>  2479
<212>  PRT
<213>  Homo sapiens

<400>  1507

Met Pro Pro Asn Ile Asn Trp Lys Glu Ile Met Lys Val Asp Pro Asp 
1               5                   10                  15      


Asp Leu Pro Arg Gln Glu Glu Leu Ala Asp Asn Leu Leu Ile Ser Leu 
            20                  25                  30          


Ser Lys Val Glu Val Asn Glu Leu Lys Ser Glu Lys Gln Glu Asn Val 
        35                  40                  45              


Ile His Leu Phe Arg Ile Thr Gln Ser Leu Met Lys Met Lys Ala Gln 
    50                  55                  60                  


Glu Val Glu Leu Ala Leu Glu Glu Val Glu Lys Ala Gly Glu Glu Gln 
65                  70                  75                  80  


Ala Lys Phe Glu Asn Gln Leu Lys Thr Lys Val Met Lys Leu Glu Asn 
                85                  90                  95      


Glu Leu Glu Met Ala Gln Gln Ser Ala Gly Gly Arg Asp Thr Arg Phe 
            100                 105                 110         


Leu Arg Asn Glu Ile Cys Gln Leu Glu Lys Gln Leu Glu Gln Lys Asp 
        115                 120                 125             


Arg Glu Leu Glu Asp Met Glu Lys Glu Leu Glu Lys Glu Lys Lys Val 
    130                 135                 140                 


Asn Glu Gln Leu Ala Leu Arg Asn Glu Glu Ala Glu Asn Glu Asn Ser 
145                 150                 155                 160 


Lys Leu Arg Arg Glu Asn Lys Arg Leu Lys Lys Lys Asn Glu Gln Leu 
                165                 170                 175     


Cys Gln Asp Ile Ile Asp Tyr Gln Lys Gln Ile Asp Ser Gln Lys Glu 
            180                 185                 190         


Thr Leu Leu Ser Arg Arg Gly Glu Asp Ser Asp Tyr Arg Ser Gln Leu 
        195                 200                 205             


Ser Lys Lys Asn Tyr Glu Leu Ile Gln Tyr Leu Asp Glu Ile Gln Thr 
    210                 215                 220                 


Leu Thr Glu Ala Asn Glu Lys Ile Glu Val Gln Asn Gln Glu Met Arg 
225                 230                 235                 240 


Lys Asn Leu Glu Glu Ser Val Gln Glu Met Glu Lys Met Thr Asp Glu 
                245                 250                 255     


Tyr Asn Arg Met Lys Ala Ile Val His Gln Thr Asp Asn Val Ile Asp 
            260                 265                 270         


Gln Leu Lys Lys Glu Asn Asp His Tyr Gln Leu Gln Val Gln Glu Leu 
        275                 280                 285             


Thr Asp Leu Leu Lys Ser Lys Asn Glu Glu Asp Asp Pro Ile Met Val 
    290                 295                 300                 


Ala Val Asn Ala Lys Val Glu Glu Trp Lys Leu Ile Leu Ser Ser Lys 
305                 310                 315                 320 


Asp Asp Glu Ile Ile Glu Tyr Gln Gln Met Leu His Asn Leu Arg Glu 
                325                 330                 335     


Lys Leu Lys Asn Ala Gln Leu Asp Ala Asp Lys Ser Asn Val Met Ala 
            340                 345                 350         


Leu Gln Gln Gly Ile Gln Glu Arg Asp Ser Gln Ile Lys Met Leu Thr 
        355                 360                 365             


Glu Gln Val Glu Gln Tyr Thr Lys Glu Met Glu Lys Asn Thr Cys Ile 
    370                 375                 380                 


Ile Glu Asp Leu Lys Asn Glu Leu Gln Arg Asn Lys Gly Ala Ser Thr 
385                 390                 395                 400 


Leu Ser Gln Gln Thr His Met Lys Ile Gln Ser Thr Leu Asp Ile Leu 
                405                 410                 415     


Lys Glu Lys Thr Lys Glu Ala Glu Arg Thr Ala Glu Leu Ala Glu Ala 
            420                 425                 430         


Asp Ala Arg Glu Lys Asp Lys Glu Leu Val Glu Ala Leu Lys Arg Leu 
        435                 440                 445             


Lys Asp Tyr Glu Ser Gly Val Tyr Gly Leu Glu Asp Ala Val Val Glu 
    450                 455                 460                 


Ile Lys Asn Cys Lys Asn Gln Ile Lys Ile Arg Asp Arg Glu Ile Glu 
465                 470                 475                 480 


Ile Leu Thr Lys Glu Ile Asn Lys Leu Glu Leu Lys Ile Ser Asp Phe 
                485                 490                 495     


Leu Asp Glu Asn Glu Ala Leu Arg Glu Arg Val Gly Leu Glu Pro Lys 
            500                 505                 510         


Thr Met Ile Asp Leu Thr Glu Phe Arg Asn Ser Lys His Leu Lys Gln 
        515                 520                 525             


Gln Gln Tyr Arg Ala Glu Asn Gln Ile Leu Leu Lys Glu Ile Glu Ser 
    530                 535                 540                 


Leu Glu Glu Glu Arg Leu Asp Leu Lys Lys Lys Ile Arg Gln Met Ala 
545                 550                 555                 560 


Gln Glu Arg Gly Lys Arg Ser Ala Thr Ser Gly Leu Thr Thr Glu Asp 
                565                 570                 575     


Leu Asn Leu Thr Glu Asn Ile Ser Gln Gly Asp Arg Ile Ser Glu Arg 
            580                 585                 590         


Lys Leu Asp Leu Leu Ser Leu Lys Asn Met Ser Glu Ala Gln Ser Lys 
        595                 600                 605             


Asn Glu Phe Leu Ser Arg Glu Leu Ile Glu Lys Glu Arg Asp Leu Glu 
    610                 615                 620                 


Arg Ser Arg Thr Val Ile Ala Lys Phe Gln Asn Lys Leu Lys Glu Leu 
625                 630                 635                 640 


Val Glu Glu Asn Lys Gln Leu Glu Glu Gly Met Lys Glu Ile Leu Gln 
                645                 650                 655     


Ala Ile Lys Glu Met Gln Lys Asp Pro Asp Val Lys Gly Gly Glu Thr 
            660                 665                 670         


Ser Leu Ile Ile Pro Ser Leu Glu Arg Leu Val Asn Ala Ile Glu Ser 
        675                 680                 685             


Lys Asn Ala Glu Gly Ile Phe Asp Ala Ser Leu His Leu Lys Ala Gln 
    690                 695                 700                 


Val Asp Gln Leu Thr Gly Arg Asn Glu Glu Leu Arg Gln Glu Leu Arg 
705                 710                 715                 720 


Glu Ser Arg Lys Glu Ala Ile Asn Tyr Ser Gln Gln Leu Ala Lys Ala 
                725                 730                 735     


Asn Leu Lys Ile Asp His Leu Glu Lys Glu Thr Ser Leu Leu Arg Gln 
            740                 745                 750         


Ser Glu Gly Ser Asn Val Val Phe Lys Gly Ile Asp Leu Pro Asp Gly 
        755                 760                 765             


Ile Ala Pro Ser Ser Ala Ser Ile Ile Asn Ser Gln Asn Glu Tyr Leu 
    770                 775                 780                 


Ile His Leu Leu Gln Glu Leu Glu Asn Lys Glu Lys Lys Leu Lys Asn 
785                 790                 795                 800 


Leu Glu Asp Ser Leu Glu Asp Tyr Asn Arg Lys Phe Ala Val Ile Arg 
                805                 810                 815     


His Gln Gln Ser Leu Leu Tyr Lys Glu Tyr Leu Ser Glu Lys Glu Thr 
            820                 825                 830         


Trp Lys Thr Glu Ser Lys Thr Ile Lys Glu Glu Lys Arg Lys Leu Glu 
        835                 840                 845             


Asp Gln Val Gln Gln Asp Ala Ile Lys Val Lys Glu Tyr Asn Asn Leu 
    850                 855                 860                 


Leu Asn Ala Leu Gln Met Asp Ser Asp Glu Met Lys Lys Ile Leu Ala 
865                 870                 875                 880 


Glu Asn Ser Arg Lys Ile Thr Val Leu Gln Val Asn Glu Lys Ser Leu 
                885                 890                 895     


Ile Arg Gln Tyr Thr Thr Leu Val Glu Leu Glu Arg Gln Leu Arg Lys 
            900                 905                 910         


Glu Asn Glu Lys Gln Lys Asn Glu Leu Leu Ser Met Glu Ala Glu Val 
        915                 920                 925             


Cys Glu Lys Ile Gly Cys Leu Gln Arg Phe Lys Glu Met Ala Ile Phe 
    930                 935                 940                 


Lys Ile Ala Ala Leu Gln Lys Val Val Asp Asn Ser Val Ser Leu Ser 
945                 950                 955                 960 


Glu Leu Glu Leu Ala Asn Lys Gln Tyr Asn Glu Leu Thr Ala Lys Tyr 
                965                 970                 975     


Arg Asp Ile Leu Gln Lys Asp Asn Met Leu Val Gln Arg Thr Ser Asn 
            980                 985                 990         


Leu Glu His Leu Glu Cys Glu Asn  Ile Ser Leu Lys Glu  Gln Val Glu 
        995                 1000                 1005             


Ser Ile  Asn Lys Glu Leu Glu  Ile Thr Lys Glu Lys  Leu His Thr 
    1010                 1015                 1020             


Ile Glu  Gln Ala Trp Glu Gln  Glu Thr Lys Leu Gly  Asn Glu Ser 
    1025                 1030                 1035             


Ser Met  Asp Lys Ala Lys Lys  Ser Ile Thr Asn Ser  Asp Ile Val 
    1040                 1045                 1050             


Ser Ile  Ser Lys Lys Ile Thr  Met Leu Glu Met Lys  Glu Leu Asn 
    1055                 1060                 1065             


Glu Arg  Gln Arg Ala Glu His  Cys Gln Lys Met Tyr  Glu His Leu 
    1070                 1075                 1080             


Arg Thr  Ser Leu Lys Gln Met  Glu Glu Arg Asn Phe  Glu Leu Glu 
    1085                 1090                 1095             


Thr Lys  Phe Ala Glu Leu Thr  Lys Ile Asn Leu Asp  Ala Gln Lys 
    1100                 1105                 1110             


Val Glu  Gln Met Leu Arg Asp  Glu Leu Ala Asp Ser  Val Ser Lys 
    1115                 1120                 1125             


Ala Val  Ser Asp Ala Asp Arg  Gln Arg Ile Leu Glu  Leu Glu Lys 
    1130                 1135                 1140             


Asn Glu  Met Glu Leu Lys Val  Glu Val Ser Lys Leu  Arg Glu Ile 
    1145                 1150                 1155             


Ser Asp  Ile Ala Arg Arg Gln  Val Glu Ile Leu Asn  Ala Gln Gln 
    1160                 1165                 1170             


Gln Ser  Arg Asp Lys Glu Val  Glu Ser Leu Arg Met  Gln Leu Leu 
    1175                 1180                 1185             


Asp Tyr  Gln Ala Gln Ser Asp  Glu Lys Ser Leu Ile  Ala Lys Leu 
    1190                 1195                 1200             


His Gln  His Asn Val Ser Leu  Gln Leu Ser Glu Ala  Thr Ala Leu 
    1205                 1210                 1215             


Gly Lys  Leu Glu Ser Ile Thr  Ser Lys Leu Gln Lys  Met Glu Ala 
    1220                 1225                 1230             


Tyr Asn  Leu Arg Leu Glu Gln  Lys Leu Asp Glu Lys  Glu Gln Ala 
    1235                 1240                 1245             


Leu Tyr  Tyr Ala Arg Leu Glu  Gly Arg Asn Arg Ala  Lys His Leu 
    1250                 1255                 1260             


Arg Gln  Thr Ile Gln Ser Leu  Arg Arg Gln Phe Ser  Gly Ala Leu 
    1265                 1270                 1275             


Pro Leu  Ala Gln Gln Glu Lys  Phe Ser Lys Thr Met  Ile Gln Leu 
    1280                 1285                 1290             


Gln Asn  Asp Lys Leu Lys Ile  Met Gln Glu Met Lys  Asn Ser Gln 
    1295                 1300                 1305             


Gln Glu  His Arg Asn Met Glu  Asn Lys Thr Leu Glu  Met Glu Leu 
    1310                 1315                 1320             


Lys Leu  Lys Gly Leu Glu Glu  Leu Ile Ser Thr Leu  Lys Asp Thr 
    1325                 1330                 1335             


Lys Gly  Ala Gln Lys Val Ile  Asn Trp His Met Lys  Ile Glu Glu 
    1340                 1345                 1350             


Leu Arg  Leu Gln Glu Leu Lys  Leu Asn Arg Glu Leu  Val Lys Asp 
    1355                 1360                 1365             


Lys Glu  Glu Ile Lys Tyr Leu  Asn Asn Ile Ile Ser  Glu Tyr Glu 
    1370                 1375                 1380             


Arg Thr  Ile Ser Ser Leu Glu  Glu Glu Ile Val Gln  Gln Asn Lys 
    1385                 1390                 1395             


Phe His  Glu Glu Arg Gln Met  Ala Trp Asp Gln Arg  Glu Val Asp 
    1400                 1405                 1410             


Leu Glu  Arg Gln Leu Asp Ile  Phe Asp Arg Gln Gln  Asn Glu Ile 
    1415                 1420                 1425             


Leu Asn  Ala Ala Gln Lys Phe  Glu Glu Ala Thr Gly  Ser Ile Pro 
    1430                 1435                 1440             


Asp Pro  Ser Leu Pro Leu Pro  Asn Gln Leu Glu Ile  Ala Leu Arg 
    1445                 1450                 1455             


Lys Ile  Lys Glu Asn Ile Arg  Ile Ile Leu Glu Thr  Arg Ala Thr 
    1460                 1465                 1470             


Cys Lys  Ser Leu Glu Glu Lys  Leu Lys Glu Lys Glu  Ser Ala Leu 
    1475                 1480                 1485             


Arg Leu  Ala Glu Gln Asn Ile  Leu Ser Arg Asp Lys  Val Ile Asn 
    1490                 1495                 1500             


Glu Leu  Arg Leu Arg Leu Pro  Ala Thr Ala Glu Arg  Glu Lys Leu 
    1505                 1510                 1515             


Ile Ala  Glu Leu Gly Arg Lys  Glu Met Glu Pro Lys  Ser His His 
    1520                 1525                 1530             


Thr Leu  Lys Ile Ala His Gln  Thr Ile Ala Asn Met  Gln Ala Arg 
    1535                 1540                 1545             


Leu Asn  Gln Lys Glu Glu Val  Leu Lys Lys Tyr Gln  Arg Leu Leu 
    1550                 1555                 1560             


Glu Lys  Ala Arg Glu Glu Gln  Arg Glu Ile Val Lys  Lys His Glu 
    1565                 1570                 1575             


Glu Asp  Leu His Ile Leu His  His Arg Leu Glu Leu  Gln Ala Asp 
    1580                 1585                 1590             


Ser Ser  Leu Asn Lys Phe Lys  Gln Thr Ala Trp Asp  Leu Met Lys 
    1595                 1600                 1605             


Gln Ser  Pro Thr Pro Val Pro  Thr Asn Lys His Phe  Ile Arg Leu 
    1610                 1615                 1620             


Ala Glu  Met Glu Gln Thr Val  Ala Glu Gln Asp Asp  Ser Leu Ser 
    1625                 1630                 1635             


Ser Leu  Leu Val Lys Leu Lys  Lys Val Ser Gln Asp  Leu Glu Arg 
    1640                 1645                 1650             


Gln Arg  Glu Ile Thr Glu Leu  Lys Val Lys Glu Phe  Glu Asn Ile 
    1655                 1660                 1665             


Lys Leu  Gln Leu Gln Glu Asn  His Glu Asp Glu Val  Lys Lys Val 
    1670                 1675                 1680             


Lys Ala  Glu Val Glu Asp Leu  Lys Tyr Leu Leu Asp  Gln Ser Gln 
    1685                 1690                 1695             


Lys Glu  Ser Gln Cys Leu Lys  Ser Glu Leu Gln Ala  Gln Lys Glu 
    1700                 1705                 1710             


Ala Asn  Ser Arg Ala Pro Thr  Thr Thr Met Arg Asn  Leu Val Glu 
    1715                 1720                 1725             


Arg Leu  Lys Ser Gln Leu Ala  Leu Lys Glu Lys Gln  Gln Lys Ala 
    1730                 1735                 1740             


Leu Ser  Arg Ala Leu Leu Glu  Leu Arg Ala Glu Met  Thr Ala Ala 
    1745                 1750                 1755             


Ala Glu  Glu Arg Ile Ile Ser  Ala Thr Ser Gln Lys  Glu Ala His 
    1760                 1765                 1770             


Leu Asn  Val Gln Gln Ile Val  Asp Arg His Thr Arg  Glu Leu Lys 
    1775                 1780                 1785             


Thr Gln  Val Glu Asp Leu Asn  Glu Asn Leu Leu Lys  Leu Lys Glu 
    1790                 1795                 1800             


Ala Leu  Lys Thr Ser Lys Asn  Arg Glu Asn Ser Leu  Thr Asp Asn 
    1805                 1810                 1815             


Leu Asn  Asp Leu Asn Asn Glu  Leu Gln Lys Lys Gln  Lys Ala Tyr 
    1820                 1825                 1830             


Asn Lys  Ile Leu Arg Glu Lys  Glu Glu Ile Asp Gln  Glu Asn Asp 
    1835                 1840                 1845             


Glu Leu  Lys Arg Gln Ile Lys  Arg Leu Thr Ser Gly  Leu Gln Gly 
    1850                 1855                 1860             


Lys Pro  Leu Thr Asp Asn Lys  Gln Ser Leu Ile Glu  Glu Leu Gln 
    1865                 1870                 1875             


Arg Lys  Val Lys Lys Leu Glu  Asn Gln Leu Glu Gly  Lys Val Glu 
    1880                 1885                 1890             


Glu Val  Asp Leu Lys Pro Met  Lys Glu Lys Asn Ala  Lys Glu Glu 
    1895                 1900                 1905             


Leu Ile  Arg Trp Glu Glu Gly  Lys Lys Trp Gln Ala  Lys Ile Glu 
    1910                 1915                 1920             


Gly Ile  Arg Asn Lys Leu Lys  Glu Lys Glu Gly Glu  Val Phe Thr 
    1925                 1930                 1935             


Leu Thr  Lys Gln Leu Asn Thr  Leu Lys Asp Leu Phe  Ala Lys Ala 
    1940                 1945                 1950             


Asp Lys  Glu Lys Leu Thr Leu  Gln Arg Lys Leu Lys  Thr Thr Gly 
    1955                 1960                 1965             


Met Thr  Val Asp Gln Val Leu  Gly Ile Arg Ala Leu  Glu Ser Glu 
    1970                 1975                 1980             


Lys Glu  Leu Glu Glu Leu Lys  Lys Arg Asn Leu Asp  Leu Glu Asn 
    1985                 1990                 1995             


Asp Ile  Leu Tyr Met Arg Ala  His Gln Ala Leu Pro  Arg Asp Ser 
    2000                 2005                 2010             


Val Val  Glu Asp Leu His Leu  Gln Asn Arg Tyr Leu  Gln Glu Lys 
    2015                 2020                 2025             


Leu His  Ala Leu Glu Lys Gln  Phe Ser Lys Asp Thr  Tyr Ser Lys 
    2030                 2035                 2040             


Pro Ser  Ile Ser Gly Ile Glu  Ser Asp Asp His Cys  Gln Arg Glu 
    2045                 2050                 2055             


Gln Glu  Leu Gln Lys Glu Asn  Leu Lys Leu Ser Ser  Glu Asn Ile 
    2060                 2065                 2070             


Glu Leu  Lys Phe Gln Leu Glu  Gln Ala Asn Lys Asp  Leu Pro Arg 
    2075                 2080                 2085             


Leu Lys  Asn Gln Val Arg Asp  Leu Lys Glu Met Cys  Glu Phe Leu 
    2090                 2095                 2100             


Lys Lys  Glu Lys Ala Glu Val  Gln Arg Lys Leu Gly  His Val Arg 
    2105                 2110                 2115             


Gly Ser  Gly Arg Ser Gly Lys  Thr Ile Pro Glu Leu  Glu Lys Thr 
    2120                 2125                 2130             


Ile Gly  Leu Met Lys Lys Val  Val Glu Lys Val Gln  Arg Glu Asn 
    2135                 2140                 2145             


Glu Gln  Leu Lys Lys Ala Ser  Gly Ile Leu Thr Ser  Glu Lys Met 
    2150                 2155                 2160             


Ala Asn  Ile Glu Gln Glu Asn  Glu Lys Leu Lys Ala  Glu Leu Glu 
    2165                 2170                 2175             


Lys Leu  Lys Ala His Leu Gly  His Gln Leu Ser Met  His Tyr Glu 
    2180                 2185                 2190             


Ser Lys  Thr Lys Gly Thr Glu  Lys Ile Ile Ala Glu  Asn Glu Arg 
    2195                 2200                 2205             


Leu Arg  Lys Glu Leu Lys Lys  Glu Thr Asp Ala Ala  Glu Lys Leu 
    2210                 2215                 2220             


Arg Ile  Ala Lys Asn Asn Leu  Glu Ile Leu Asn Glu  Lys Met Thr 
    2225                 2230                 2235             


Val Gln  Leu Glu Glu Thr Gly  Lys Arg Leu Gln Phe  Ala Glu Ser 
    2240                 2245                 2250             


Arg Gly  Pro Gln Leu Glu Gly  Ala Asp Ser Lys Ser  Trp Lys Ser 
    2255                 2260                 2265             


Ile Val  Val Thr Arg Met Tyr  Glu Thr Lys Leu Lys  Glu Leu Glu 
    2270                 2275                 2280             


Thr Asp  Ile Ala Lys Lys Asn  Gln Ser Ile Thr Asp  Leu Lys Gln 
    2285                 2290                 2295             


Leu Val  Lys Glu Ala Thr Glu  Arg Glu Gln Lys Val  Asn Lys Tyr 
    2300                 2305                 2310             


Asn Glu  Asp Leu Glu Gln Gln  Ile Lys Ile Leu Lys  His Val Pro 
    2315                 2320                 2325             


Glu Gly  Ala Glu Thr Glu Gln  Gly Leu Lys Arg Glu  Leu Gln Val 
    2330                 2335                 2340             


Leu Arg  Leu Ala Asn His Gln  Leu Asp Lys Glu Lys  Ala Glu Leu 
    2345                 2350                 2355             


Ile His  Gln Ile Glu Ala Asn  Lys Asp Gln Ser Gly  Ala Glu Ser 
    2360                 2365                 2370             


Thr Ile  Pro Asp Ala Asp Gln  Leu Lys Glu Lys Ile  Lys Asp Leu 
    2375                 2380                 2385             


Glu Thr  Gln Leu Lys Met Ser  Asp Leu Glu Lys Gln  His Leu Lys 
    2390                 2395                 2400             


Glu Glu  Ile Lys Lys Leu Lys  Lys Glu Leu Glu Asn  Phe Asp Pro 
    2405                 2410                 2415             


Ser Phe  Phe Glu Glu Ile Glu  Asp Leu Lys Tyr Asn  Tyr Lys Glu 
    2420                 2425                 2430             


Glu Val  Lys Lys Asn Ile Leu  Leu Glu Glu Lys Val  Lys Lys Leu 
    2435                 2440                 2445             


Ser Glu  Gln Leu Gly Val Glu  Leu Thr Ser Pro Val  Ala Ala Ser 
    2450                 2455                 2460             


Glu Glu  Phe Glu Asp Glu Glu  Glu Ser Pro Val Asn  Phe Pro Ile 
    2465                 2470                 2475             


Tyr 
    


<210>  1508
<211>  190
<212>  PRT
<213>  Homo sapiens

<400>  1508

Met Phe Gln Val Pro Asp Ser Glu Gly Gly Arg Ala Gly Ser Arg Ala 
1               5                   10                  15      


Met Lys Pro Pro Gly Gly Glu Ser Ser Asn Leu Phe Gly Ser Pro Glu 
            20                  25                  30          


Glu Ala Thr Pro Ser Ser Arg Pro Asn Arg Met Ala Ser Asn Ile Phe 
        35                  40                  45              


Gly Pro Thr Glu Glu Pro Gln Asn Ile Pro Lys Arg Thr Asn Pro Pro 
    50                  55                  60                  


Gly Gly Lys Gly Ser Gly Ile Phe Asp Glu Ser Thr Pro Val Gln Thr 
65                  70                  75                  80  


Arg Gln His Leu Asn Pro Pro Gly Gly Lys Thr Ser Asp Ile Phe Gly 
                85                  90                  95      


Ser Pro Val Thr Ala Thr Ser Arg Leu Ala His Pro Asn Lys Pro Lys 
            100                 105                 110         


Asp His Val Phe Leu Cys Glu Gly Glu Glu Pro Lys Ser Asp Leu Lys 
        115                 120                 125             


Ala Ala Arg Ser Ile Pro Ala Gly Ala Glu Pro Gly Glu Lys Gly Ser 
    130                 135                 140                 


Ala Arg Lys Ala Gly Pro Ala Lys Glu Gln Glu Pro Met Pro Thr Val 
145                 150                 155                 160 


Asp Ser His Glu Pro Arg Leu Gly Pro Arg Pro Arg Ser His Asn Lys 
                165                 170                 175     


Val Leu Asn Pro Pro Gly Gly Lys Ser Ser Ile Ser Phe Tyr 
            180                 185                 190 


<210>  1509
<211>  376
<212>  PRT
<213>  Homo sapiens

<400>  1509

Met Gly Gly Gly Gly Ser Ala Leu Arg Val Cys Ala Asp His Arg Gly 
1               5                   10                  15      


Gly Ile Asn Trp Leu Ser Leu Ser Pro Asp Gly Gln Arg Leu Leu Thr 
            20                  25                  30          


Gly Ser Glu Asp Gly Thr Ala Arg Leu Trp Ser Thr Ala Asp Gly Gln 
        35                  40                  45              


Cys Cys Ala Leu Leu Gln Gly His Glu Ser Tyr Val Thr Phe Cys Gln 
    50                  55                  60                  


Leu Glu Asp Glu Ala Ala Phe Thr Cys Ser Ala Asp Cys Thr Ile Arg 
65                  70                  75                  80  


Arg Trp Asp Val Leu Thr Gly Gln Cys Leu Gln Val Tyr Arg Gly His 
                85                  90                  95      


Thr Ser Ile Val Asn Arg Ile Leu Val Ala Asn Asn Gln Leu Phe Ser 
            100                 105                 110         


Ser Ser Tyr Asp Arg Thr Ala Arg Val Trp Ser Val Asp Lys Gly Gln 
        115                 120                 125             


Met Ser Arg Glu Phe Arg Gly His Arg Asn Cys Val Leu Thr Leu Ala 
    130                 135                 140                 


Tyr Ser Ala Pro Trp Asp Leu Pro Ser Thr Pro Cys Ala Glu Glu Ala 
145                 150                 155                 160 


Ala Ala Gly Gly Leu Leu Val Thr Gly Ser Thr Asp Gly Thr Ala Lys 
                165                 170                 175     


Val Trp Gln Val Ala Ser Gly Cys Cys His Gln Thr Leu Arg Gly His 
            180                 185                 190         


Thr Gly Ala Val Leu Cys Leu Val Leu Asp Thr Pro Gly His Thr Ala 
        195                 200                 205             


Phe Thr Gly Ser Thr Asp Ala Thr Ile Arg Ala Trp Asp Ile Leu Ser 
    210                 215                 220                 


Gly Glu Gln Leu Arg Val Phe Arg Glu His Arg Gly Ser Val Ile Cys 
225                 230                 235                 240 


Leu Glu Leu Val Asn Arg Leu Val Tyr Ser Gly Ser Ala Asp Arg Thr 
                245                 250                 255     


Val Lys Cys Trp Leu Ala Asp Thr Gly Glu Cys Val Arg Thr Phe Thr 
            260                 265                 270         


Ala His Arg Arg Asn Val Ser Ala Leu Lys Tyr His Ala Gly Thr Leu 
        275                 280                 285             


Phe Thr Gly Ser Gly Asp Ala Cys Ala Arg Ala Phe Asp Ala Gln Ser 
    290                 295                 300                 


Gly Glu Leu Arg Arg Val Phe Arg Gly His Thr Phe Ile Ile Asn Cys 
305                 310                 315                 320 


Ile Gln Val His Gly Gln Val Leu Tyr Thr Ala Ser His Asp Gly Ala 
                325                 330                 335     


Leu Arg Leu Trp Asp Val Arg Gly Leu Arg Gly Ala Pro Arg Pro Pro 
            340                 345                 350         


Pro Pro Met Arg Ser Leu Ser Arg Leu Phe Ser Asn Lys Val Gly Cys 
        355                 360                 365             


Ala Ala Ala Pro Leu Gln Pro Ala 
    370                 375     


<210>  1510
<211>  0
<212>  PRT
<213>  Homo sapiens

<400>  1510
<210>  1511
<211>  360
<212>  PRT
<213>  Homo sapiens

<400>  1511

Met Cys Lys Ala Gly Phe Ala Gly Asp Asp Ala Pro Arg Ala Val Phe 
1               5                   10                  15      


Pro Ser Ile Val Gly Arg Pro Arg His Gln Gly Val Met Val Gly Met 
            20                  25                  30          


Gly Gln Lys Asp Ser Tyr Val Gly Asp Glu Ala Gln Ser Lys Arg Gly 
        35                  40                  45              


Ile Leu Thr Leu Lys Tyr Pro Ile Glu His Gly Ile Val Thr Asn Trp 
    50                  55                  60                  


Asp Asp Met Glu Lys Ile Trp His His Thr Phe Tyr Asn Glu Leu Arg 
65                  70                  75                  80  


Val Ala Pro Glu Glu His Pro Val Leu Leu Thr Glu Ala Pro Leu Asn 
                85                  90                  95      


Pro Lys Ala Asn Leu Glu Lys Met Thr Gln Ile Met Phe Glu Thr Phe 
            100                 105                 110         


Asn Thr Pro Ala Met Tyr Val Ala Ile Gln Ala Val Leu Ser Leu Tyr 
        115                 120                 125             


Ala Ser Gly Arg Thr Thr Gly Ile Val Met Asp Ser Gly Asp Gly Val 
    130                 135                 140                 


Thr His Thr Val Pro Ile Tyr Glu Gly Tyr Ala Leu Pro His Ala Ile 
145                 150                 155                 160 


Leu Arg Leu Asp Leu Ala Gly Arg Asp Leu Thr Asp Tyr Leu Met Lys 
                165                 170                 175     


Ile Leu Thr Glu Arg Gly Tyr Ser Phe Thr Thr Thr Ala Glu Arg Glu 
            180                 185                 190         


Ile Val Arg Asp Ile Lys Glu Lys Leu Cys Tyr Val Ala Leu Asp Phe 
        195                 200                 205             


Glu Gln Glu Met Ala Thr Ala Ala Ser Ser Ser Ser Leu Glu Lys Ser 
    210                 215                 220                 


Tyr Glu Leu Pro Asp Gly Gln Val Ile Thr Ile Gly Asn Glu Arg Phe 
225                 230                 235                 240 


Arg Cys Pro Glu Ala Leu Phe Gln Pro Ser Phe Leu Gly Met Glu Ser 
                245                 250                 255     


Cys Gly Ile His Glu Thr Thr Phe Asn Ser Ile Met Lys Cys Asp Val 
            260                 265                 270         


Asp Ile Arg Lys Asp Leu Tyr Ala Asn Thr Val Leu Ser Gly Gly Thr 
        275                 280                 285             


Thr Met Tyr Pro Gly Ile Ala Asp Arg Met Gln Lys Glu Ile Thr Ala 
    290                 295                 300                 


Leu Ala Pro Ser Thr Met Lys Ile Lys Ile Ile Ala Pro Pro Glu Arg 
305                 310                 315                 320 


Lys Tyr Ser Val Trp Ile Gly Gly Ser Ile Leu Ala Ser Leu Ser Thr 
                325                 330                 335     


Phe Gln Gln Met Trp Ile Ser Lys Gln Glu Tyr Asp Glu Ser Gly Pro 
            340                 345                 350         


Ser Ile Val His Arg Lys Cys Phe 
        355                 360 


<210>  1512
<211>  553
<212>  PRT
<213>  Homo sapiens

<400>  1512

Met Leu Ser Val Arg Val Ala Ala Ala Val Val Arg Ala Leu Pro Arg 
1               5                   10                  15      


Arg Ala Gly Leu Val Ser Arg Asn Ala Leu Gly Ser Ser Phe Ile Ala 
            20                  25                  30          


Ala Arg Asn Phe His Ala Ser Asn Thr His Leu Gln Lys Thr Gly Thr 
        35                  40                  45              


Ala Glu Met Ser Ser Ile Leu Glu Glu Arg Ile Leu Gly Ala Asp Thr 
    50                  55                  60                  


Ser Val Asp Leu Glu Glu Thr Gly Arg Val Leu Ser Ile Gly Asp Gly 
65                  70                  75                  80  


Ile Ala Arg Val His Gly Leu Arg Asn Val Gln Ala Glu Glu Met Val 
                85                  90                  95      


Glu Phe Ser Ser Gly Leu Lys Gly Met Ser Leu Asn Leu Glu Pro Asp 
            100                 105                 110         


Asn Val Gly Val Val Val Phe Gly Asn Asp Lys Leu Ile Lys Glu Gly 
        115                 120                 125             


Asp Ile Val Lys Arg Thr Gly Ala Ile Val Asp Val Pro Val Gly Glu 
    130                 135                 140                 


Glu Leu Leu Gly Arg Val Val Asp Ala Leu Gly Asn Ala Ile Asp Gly 
145                 150                 155                 160 


Lys Gly Pro Ile Gly Ser Lys Thr Arg Arg Arg Val Gly Leu Lys Ala 
                165                 170                 175     


Pro Gly Ile Ile Pro Arg Ile Ser Val Arg Glu Pro Met Gln Thr Gly 
            180                 185                 190         


Ile Lys Ala Val Asp Ser Leu Val Pro Ile Gly Arg Gly Gln Arg Glu 
        195                 200                 205             


Leu Ile Ile Gly Asp Arg Gln Thr Gly Lys Thr Ser Ile Ala Ile Asp 
    210                 215                 220                 


Thr Ile Ile Asn Gln Lys Arg Phe Asn Asp Gly Ser Asp Glu Lys Lys 
225                 230                 235                 240 


Lys Leu Tyr Cys Ile Tyr Val Ala Ile Gly Gln Lys Arg Ser Thr Val 
                245                 250                 255     


Ala Gln Leu Val Lys Arg Leu Thr Asp Ala Asp Ala Met Lys Tyr Thr 
            260                 265                 270         


Ile Val Val Ser Ala Thr Ala Ser Asp Ala Ala Pro Leu Gln Tyr Leu 
        275                 280                 285             


Ala Pro Tyr Ser Gly Cys Ser Met Gly Glu Tyr Phe Arg Asp Asn Gly 
    290                 295                 300                 


Lys His Ala Leu Ile Ile Tyr Asp Asp Leu Ser Lys Gln Ala Val Ala 
305                 310                 315                 320 


Tyr Arg Gln Met Ser Leu Leu Leu Arg Arg Pro Pro Gly Arg Glu Ala 
                325                 330                 335     


Tyr Pro Gly Asp Val Phe Tyr Leu His Ser Arg Leu Leu Glu Arg Ala 
            340                 345                 350         


Ala Lys Met Asn Asp Ala Phe Gly Gly Gly Ser Leu Thr Ala Leu Pro 
        355                 360                 365             


Val Ile Glu Thr Gln Ala Gly Asp Val Ser Ala Tyr Ile Pro Thr Asn 
    370                 375                 380                 


Val Ile Ser Ile Thr Asp Gly Gln Ile Phe Leu Glu Thr Glu Leu Phe 
385                 390                 395                 400 


Tyr Lys Gly Ile Arg Pro Ala Ile Asn Val Gly Leu Ser Val Ser Arg 
                405                 410                 415     


Val Gly Ser Ala Ala Gln Thr Arg Ala Met Lys Gln Val Ala Gly Thr 
            420                 425                 430         


Met Lys Leu Glu Leu Ala Gln Tyr Arg Glu Val Ala Ala Phe Ala Gln 
        435                 440                 445             


Phe Gly Ser Asp Leu Asp Ala Ala Thr Gln Gln Leu Leu Ser Arg Gly 
    450                 455                 460                 


Val Arg Leu Thr Glu Leu Leu Lys Gln Gly Gln Tyr Ser Pro Met Ala 
465                 470                 475                 480 


Ile Glu Glu Gln Val Ala Val Ile Tyr Ala Gly Val Arg Gly Tyr Leu 
                485                 490                 495     


Asp Lys Leu Glu Pro Ser Lys Ile Thr Lys Phe Glu Asn Ala Phe Leu 
            500                 505                 510         


Ser His Val Val Ser Gln His Gln Ala Leu Leu Gly Thr Ile Arg Ala 
        515                 520                 525             


Asp Gly Lys Ile Ser Glu Gln Ser Asp Ala Lys Leu Lys Glu Ile Val 
    530                 535                 540                 


Thr Asn Phe Leu Ala Gly Phe Glu Ala 
545                 550             


<210>  1513
<211>  529
<212>  PRT
<213>  Homo sapiens

<400>  1513

Met Leu Gly Phe Val Gly Arg Val Ala Ala Ala Pro Ala Ser Gly Ala 
1               5                   10                  15      


Leu Arg Arg Leu Thr Pro Ser Ala Ser Leu Pro Pro Ala Gln Leu Leu 
            20                  25                  30          


Leu Arg Ala Ala Pro Thr Ala Val His Pro Val Arg Asp Tyr Ala Ala 
        35                  40                  45              


Gln Thr Ser Pro Ser Pro Lys Ala Gly Ala Ala Thr Gly Arg Ile Val 
    50                  55                  60                  


Ala Val Ile Gly Ala Val Val Asp Val Gln Phe Asp Glu Gly Leu Pro 
65                  70                  75                  80  


Pro Ile Leu Asn Ala Leu Glu Val Gln Gly Arg Glu Thr Arg Leu Val 
                85                  90                  95      


Leu Glu Val Ala Gln His Leu Gly Glu Ser Thr Val Arg Thr Ile Ala 
            100                 105                 110         


Met Asp Gly Thr Glu Gly Leu Val Arg Gly Gln Lys Val Leu Asp Ser 
        115                 120                 125             


Gly Ala Pro Ile Lys Ile Pro Val Gly Pro Glu Thr Leu Gly Arg Ile 
    130                 135                 140                 


Met Asn Val Ile Gly Glu Pro Ile Asp Glu Arg Gly Pro Ile Lys Thr 
145                 150                 155                 160 


Lys Gln Phe Ala Pro Ile His Ala Glu Ala Pro Glu Phe Met Glu Met 
                165                 170                 175     


Ser Val Glu Gln Glu Ile Leu Val Thr Gly Ile Lys Val Val Asp Leu 
            180                 185                 190         


Leu Ala Pro Tyr Ala Lys Gly Gly Lys Ile Gly Leu Phe Gly Gly Ala 
        195                 200                 205             


Gly Val Gly Lys Thr Val Leu Ile Met Glu Leu Ile Asn Asn Val Ala 
    210                 215                 220                 


Lys Ala His Gly Gly Tyr Ser Val Phe Ala Gly Val Gly Glu Arg Thr 
225                 230                 235                 240 


Arg Glu Gly Asn Asp Leu Tyr His Glu Met Ile Glu Ser Gly Val Ile 
                245                 250                 255     


Asn Leu Lys Asp Ala Thr Ser Lys Val Ala Leu Val Tyr Gly Gln Met 
            260                 265                 270         


Asn Glu Pro Pro Gly Ala Arg Ala Arg Val Ala Leu Thr Gly Leu Thr 
        275                 280                 285             


Val Ala Glu Tyr Phe Arg Asp Gln Glu Gly Gln Asp Val Leu Leu Phe 
    290                 295                 300                 


Ile Asp Asn Ile Phe Arg Phe Thr Gln Ala Gly Ser Glu Val Ser Ala 
305                 310                 315                 320 


Leu Leu Gly Arg Ile Pro Ser Ala Val Gly Tyr Gln Pro Thr Leu Ala 
                325                 330                 335     


Thr Asp Met Gly Thr Met Gln Glu Arg Ile Thr Thr Thr Lys Lys Gly 
            340                 345                 350         


Ser Ile Thr Ser Val Gln Ala Ile Tyr Val Pro Ala Asp Asp Leu Thr 
        355                 360                 365             


Asp Pro Ala Pro Ala Thr Thr Phe Ala His Leu Asp Ala Thr Thr Val 
    370                 375                 380                 


Leu Ser Arg Ala Ile Ala Glu Leu Gly Ile Tyr Pro Ala Val Asp Pro 
385                 390                 395                 400 


Leu Asp Ser Thr Ser Arg Ile Met Asp Pro Asn Ile Val Gly Ser Glu 
                405                 410                 415     


His Tyr Asp Val Ala Arg Gly Val Gln Lys Ile Leu Gln Asp Tyr Lys 
            420                 425                 430         


Ser Leu Gln Asp Ile Ile Ala Ile Leu Gly Met Asp Glu Leu Ser Glu 
        435                 440                 445             


Glu Asp Lys Leu Thr Val Ser Arg Ala Arg Lys Ile Gln Arg Phe Leu 
    450                 455                 460                 


Ser Gln Pro Phe Gln Val Ala Glu Val Phe Thr Gly His Met Gly Lys 
465                 470                 475                 480 


Leu Val Pro Leu Lys Glu Thr Ile Lys Gly Phe Gln Gln Ile Leu Ala 
                485                 490                 495     


Gly Glu Tyr Asp His Leu Pro Glu Gln Ala Phe Tyr Met Val Gly Pro 
            500                 505                 510         


Ile Glu Glu Ala Val Ala Lys Ala Asp Lys Leu Ala Glu Glu His Ser 
        515                 520                 525             


Ser 
    


<210>  1514
<211>  298
<212>  PRT
<213>  Homo sapiens

<400>  1514

Met Val Arg Met Val Pro Val Leu Leu Ser Leu Leu Leu Leu Leu Gly 
1               5                   10                  15      


Pro Ala Val Pro Gln Glu Asn Gln Asp Gly Arg Tyr Ser Leu Thr Tyr 
            20                  25                  30          


Ile Tyr Thr Gly Leu Ser Lys His Val Glu Asp Val Pro Ala Phe Gln 
        35                  40                  45              


Ala Leu Gly Ser Leu Asn Asp Leu Gln Phe Phe Arg Tyr Asn Ser Lys 
    50                  55                  60                  


Asp Arg Lys Ser Gln Pro Met Gly Leu Trp Arg Gln Val Glu Gly Met 
65                  70                  75                  80  


Glu Asp Trp Lys Gln Asp Ser Gln Leu Gln Lys Ala Arg Glu Asp Ile 
                85                  90                  95      


Phe Met Glu Thr Leu Lys Asp Ile Val Glu Tyr Tyr Asn Asp Ser Asn 
            100                 105                 110         


Gly Ser His Val Leu Gln Gly Arg Phe Gly Cys Glu Ile Glu Asn Asn 
        115                 120                 125             


Arg Ser Ser Gly Ala Phe Trp Lys Tyr Tyr Tyr Asp Gly Lys Asp Tyr 
    130                 135                 140                 


Ile Glu Phe Asn Lys Glu Ile Pro Ala Trp Val Pro Phe Asp Pro Ala 
145                 150                 155                 160 


Ala Gln Ile Thr Lys Gln Lys Trp Glu Ala Glu Pro Val Tyr Val Gln 
                165                 170                 175     


Arg Ala Lys Ala Tyr Leu Glu Glu Glu Cys Pro Ala Thr Leu Arg Lys 
            180                 185                 190         


Tyr Leu Lys Tyr Ser Lys Asn Ile Leu Asp Arg Gln Asp Pro Pro Ser 
        195                 200                 205             


Val Val Val Thr Ser His Gln Ala Pro Gly Glu Lys Lys Lys Leu Lys 
    210                 215                 220                 


Cys Leu Ala Tyr Asp Phe Tyr Pro Gly Lys Ile Asp Val His Trp Thr 
225                 230                 235                 240 


Arg Ala Gly Glu Val Gln Glu Pro Glu Leu Arg Gly Asp Val Leu His 
                245                 250                 255     


Asn Gly Asn Gly Thr Tyr Gln Ser Trp Val Val Val Ala Val Pro Pro 
            260                 265                 270         


Gln Asp Thr Ala Pro Tyr Ser Cys His Val Gln His Ser Ser Leu Ala 
        275                 280                 285             


Gln Pro Leu Val Val Pro Trp Glu Ala Ser 
    290                 295             


<210>  1515
<211>  454
<212>  PRT
<213>  Homo sapiens

<400>  1515

Met Pro Arg Cys Pro Ala Gly Ala Met Asp Glu Gly Pro Val Asp Leu 
1               5                   10                  15      


Arg Thr Arg Pro Lys Ala Ala Gly Leu Pro Gly Ala Ala Leu Pro Leu 
            20                  25                  30          


Arg Lys Arg Pro Leu Arg Ala Pro Ser Pro Glu Pro Ala Ala Pro Arg 
        35                  40                  45              


Gly Ala Ala Gly Leu Val Val Pro Leu Asp Pro Leu Arg Gly Gly Cys 
    50                  55                  60                  


Asp Leu Pro Ala Val Pro Gly Pro Pro His Gly Leu Ala Arg Pro Glu 
65                  70                  75                  80  


Ala Leu Tyr Tyr Pro Gly Ala Leu Leu Pro Leu Tyr Pro Thr Arg Ala 
                85                  90                  95      


Met Gly Ser Pro Phe Pro Leu Val Asn Leu Pro Thr Pro Leu Tyr Pro 
            100                 105                 110         


Met Met Cys Pro Met Glu His Pro Leu Ser Ala Asp Ile Ala Met Ala 
        115                 120                 125             


Thr Arg Ala Asp Glu Asp Gly Asp Thr Pro Leu His Ile Ala Val Val 
    130                 135                 140                 


Gln Gly Asn Leu Pro Ala Val His Arg Leu Val Asn Leu Phe Gln Gln 
145                 150                 155                 160 


Gly Gly Arg Glu Leu Asp Ile Tyr Asn Asn Leu Arg Gln Thr Pro Leu 
                165                 170                 175     


His Leu Ala Val Ile Thr Thr Leu Pro Ser Val Val Arg Leu Leu Val 
            180                 185                 190         


Thr Ala Gly Ala Ser Pro Met Ala Leu Asp Arg His Gly Gln Thr Ala 
        195                 200                 205             


Ala His Leu Ala Cys Glu His Arg Ser Pro Thr Cys Leu Arg Ala Leu 
    210                 215                 220                 


Leu Asp Ser Ala Ala Pro Gly Thr Leu Asp Leu Glu Ala Arg Asn Tyr 
225                 230                 235                 240 


Asp Gly Leu Thr Ala Leu His Val Ala Val Asn Thr Glu Cys Gln Glu 
                245                 250                 255     


Thr Val Gln Leu Leu Leu Glu Arg Gly Ala Asp Ile Asp Ala Val Asp 
            260                 265                 270         


Ile Lys Ser Gly Arg Ser Pro Leu Ile His Ala Val Glu Asn Asn Ser 
        275                 280                 285             


Leu Ser Met Val Gln Leu Leu Leu Gln His Gly Ala Asn Val Asn Ala 
    290                 295                 300                 


Gln Met Tyr Ser Gly Ser Ser Ala Leu His Ser Ala Ser Gly Arg Gly 
305                 310                 315                 320 


Leu Leu Pro Leu Val Arg Thr Leu Val Arg Ser Gly Ala Asp Ser Ser 
                325                 330                 335     


Leu Lys Asn Cys His Asn Asp Thr Pro Leu Met Val Ala Arg Ser Arg 
            340                 345                 350         


Arg Val Ile Asp Ile Leu Arg Gly Lys Ala Thr Arg Pro Ala Ser Thr 
        355                 360                 365             


Ser Gln Pro Asp Pro Ser Pro Asp Arg Ser Ala Asn Thr Ser Pro Glu 
    370                 375                 380                 


Ser Ser Ser Arg Leu Ser Ser Asn Gly Leu Leu Ser Ala Ser Pro Ser 
385                 390                 395                 400 


Ser Ser Pro Ser Gln Ser Pro Pro Arg Asp Pro Pro Gly Phe Pro Met 
                405                 410                 415     


Ala Pro Pro Asn Phe Phe Leu Pro Ser Pro Ser Pro Pro Ala Phe Leu 
            420                 425                 430         


Pro Phe Ala Gly Val Leu Arg Gly Pro Gly Arg Pro Val Pro Pro Ser 
        435                 440                 445             


Pro Ala Pro Gly Gly Ser 
    450                 


<210>  1516
<211>  1263
<212>  PRT
<213>  Homo sapiens

<400>  1516

Met Glu Pro Pro Gly Gly Ser Leu Gly Pro Gly Arg Gly Thr Arg Asp 
1               5                   10                  15      


Lys Lys Lys Gly Arg Ser Pro Asp Glu Leu Pro Ser Ala Gly Gly Asp 
            20                  25                  30          


Gly Gly Lys Ser Lys Lys Phe Leu Glu Arg Phe Thr Ser Met Arg Ile 
        35                  40                  45              


Lys Lys Glu Lys Glu Lys Pro Asn Ser Ala His Arg Asn Ser Ser Ala 
    50                  55                  60                  


Ser Tyr Gly Asp Asp Pro Thr Ala Gln Ser Leu Gln Asp Val Ser Asp 
65                  70                  75                  80  


Glu Gln Val Leu Val Leu Phe Glu Gln Met Leu Leu Asp Met Asn Leu 
                85                  90                  95      


Asn Glu Glu Lys Gln Gln Pro Leu Arg Glu Lys Asp Ile Ile Ile Lys 
            100                 105                 110         


Arg Glu Met Val Ser Gln Tyr Leu Tyr Thr Ser Lys Ala Gly Met Ser 
        115                 120                 125             


Gln Lys Glu Ser Ser Lys Ser Ala Met Met Tyr Ile Gln Glu Leu Arg 
    130                 135                 140                 


Ser Gly Leu Arg Asp Met Pro Leu Leu Ser Cys Leu Glu Ser Leu Arg 
145                 150                 155                 160 


Val Ser Leu Asn Asn Asn Pro Val Ser Trp Val Gln Thr Phe Gly Ala 
                165                 170                 175     


Glu Gly Leu Ala Ser Leu Leu Asp Ile Leu Lys Arg Leu His Asp Glu 
            180                 185                 190         


Lys Glu Glu Thr Ala Gly Ser Tyr Asp Ser Arg Asn Lys His Glu Ile 
        195                 200                 205             


Ile Arg Cys Leu Lys Ala Phe Met Asn Asn Lys Phe Gly Ile Lys Thr 
    210                 215                 220                 


Met Leu Glu Thr Glu Glu Gly Ile Leu Leu Leu Val Arg Ala Met Asp 
225                 230                 235                 240 


Pro Ala Val Pro Asn Met Met Ile Asp Ala Ala Lys Leu Leu Ser Ala 
                245                 250                 255     


Leu Cys Ile Leu Pro Gln Pro Glu Asp Met Asn Glu Arg Val Leu Glu 
            260                 265                 270         


Ala Met Thr Glu Arg Ala Glu Met Asp Glu Val Glu Arg Phe Gln Pro 
        275                 280                 285             


Leu Leu Asp Gly Leu Lys Ser Gly Thr Thr Ile Ala Leu Lys Val Gly 
    290                 295                 300                 


Cys Leu Gln Leu Ile Asn Ala Leu Ile Thr Pro Ala Glu Glu Leu Asp 
305                 310                 315                 320 


Phe Arg Val His Ile Arg Ser Glu Leu Met Arg Leu Gly Leu His Gln 
                325                 330                 335     


Val Leu Gln Asp Leu Arg Glu Ile Glu Asn Glu Asp Met Arg Val Gln 
            340                 345                 350         


Leu Asn Val Phe Asp Glu Gln Gly Glu Glu Asp Ser Tyr Asp Leu Lys 
        355                 360                 365             


Gly Arg Leu Asp Asp Ile Arg Met Glu Met Asp Asp Phe Asn Glu Val 
    370                 375                 380                 


Phe Gln Ile Leu Leu Asn Thr Val Lys Asp Ser Lys Ala Glu Pro His 
385                 390                 395                 400 


Phe Leu Ser Ile Leu Gln His Leu Leu Leu Val Arg Asn Asp Tyr Glu 
                405                 410                 415     


Ala Arg Pro Gln Tyr Tyr Lys Leu Ile Glu Glu Cys Ile Ser Gln Ile 
            420                 425                 430         


Val Leu His Lys Asn Gly Ala Asp Pro Asp Phe Lys Cys Arg His Leu 
        435                 440                 445             


Gln Ile Glu Ile Glu Gly Leu Ile Asp Gln Met Ile Asp Lys Thr Lys 
    450                 455                 460                 


Val Glu Lys Ser Glu Ala Lys Ala Ala Glu Leu Glu Lys Lys Leu Asp 
465                 470                 475                 480 


Ser Glu Leu Thr Ala Arg His Glu Leu Gln Val Glu Met Lys Lys Met 
                485                 490                 495     


Glu Ser Asp Phe Glu Gln Lys Leu Gln Asp Leu Gln Gly Glu Lys Asp 
            500                 505                 510         


Ala Leu His Ser Glu Lys Gln Gln Ile Ala Thr Glu Lys Gln Asp Leu 
        515                 520                 525             


Glu Ala Glu Val Ser Gln Leu Thr Gly Glu Val Ala Lys Leu Thr Lys 
    530                 535                 540                 


Glu Leu Glu Asp Ala Lys Lys Glu Met Ala Ser Leu Ser Ala Ala Ala 
545                 550                 555                 560 


Ile Thr Val Pro Pro Ser Val Pro Ser Arg Ala Pro Val Pro Pro Ala 
                565                 570                 575     


Pro Pro Leu Pro Gly Asp Ser Gly Thr Ile Ile Pro Pro Pro Pro Ala 
            580                 585                 590         


Pro Gly Asp Ser Thr Thr Pro Pro Pro Pro Pro Pro Pro Pro Pro Pro 
        595                 600                 605             


Pro Pro Pro Leu Pro Gly Gly Val Cys Ile Ser Ser Pro Pro Ser Leu 
    610                 615                 620                 


Pro Gly Gly Thr Ala Ile Ser Pro Pro Pro Pro Leu Ser Gly Asp Ala 
625                 630                 635                 640 


Thr Ile Pro Pro Pro Pro Pro Leu Pro Glu Gly Val Gly Ile Pro Ser 
                645                 650                 655     


Pro Ser Ser Leu Pro Gly Gly Thr Ala Ile Pro Pro Pro Pro Pro Leu 
            660                 665                 670         


Pro Gly Ser Ala Arg Ile Pro Pro Pro Pro Pro Pro Leu Pro Gly Ser 
        675                 680                 685             


Ala Gly Ile Pro Pro Pro Pro Pro Pro Leu Pro Gly Glu Ala Gly Met 
    690                 695                 700                 


Pro Pro Pro Pro Pro Pro Leu Pro Gly Gly Pro Gly Ile Pro Pro Pro 
705                 710                 715                 720 


Pro Pro Phe Pro Gly Gly Pro Gly Ile Pro Pro Pro Pro Pro Gly Met 
                725                 730                 735     


Gly Met Pro Pro Pro Pro Pro Phe Gly Phe Gly Val Pro Ala Ala Pro 
            740                 745                 750         


Val Leu Pro Phe Gly Leu Thr Pro Lys Lys Leu Tyr Lys Pro Glu Val 
        755                 760                 765             


Gln Leu Arg Arg Pro Asn Trp Ser Lys Leu Val Ala Glu Asp Leu Ser 
    770                 775                 780                 


Gln Asp Cys Phe Trp Thr Lys Val Lys Glu Asp Arg Phe Glu Asn Asn 
785                 790                 795                 800 


Glu Leu Phe Ala Lys Leu Thr Leu Thr Phe Ser Ala Gln Thr Lys Thr 
                805                 810                 815     


Ser Lys Ala Lys Lys Asp Gln Glu Gly Gly Glu Glu Lys Lys Ser Val 
            820                 825                 830         


Gln Lys Lys Lys Val Lys Glu Leu Lys Val Leu Asp Ser Lys Thr Ala 
        835                 840                 845             


Gln Asn Leu Ser Ile Phe Leu Gly Ser Phe Arg Met Pro Tyr Gln Glu 
    850                 855                 860                 


Ile Lys Asn Val Ile Leu Glu Val Asn Glu Ala Val Leu Thr Glu Ser 
865                 870                 875                 880 


Met Ile Gln Asn Leu Ile Lys Gln Met Pro Glu Pro Glu Gln Leu Lys 
                885                 890                 895     


Met Leu Ser Glu Leu Lys Asp Glu Tyr Asp Asp Leu Ala Glu Ser Glu 
            900                 905                 910         


Gln Phe Gly Val Val Met Gly Thr Val Pro Arg Leu Arg Pro Arg Leu 
        915                 920                 925             


Asn Ala Ile Leu Phe Lys Leu Gln Phe Ser Glu Gln Val Glu Asn Ile 
    930                 935                 940                 


Lys Pro Glu Ile Val Ser Val Thr Ala Ala Cys Glu Glu Leu Arg Lys 
945                 950                 955                 960 


Ser Glu Ser Phe Ser Asn Leu Leu Glu Ile Thr Leu Leu Val Gly Asn 
                965                 970                 975     


Tyr Met Asn Ala Gly Ser Arg Asn Ala Gly Ala Phe Gly Phe Asn Ile 
            980                 985                 990         


Ser Phe Leu Cys Lys Leu Arg Asp  Thr Lys Ser Thr Asp  Gln Lys Met 
        995                 1000                 1005             


Thr Leu  Leu His Phe Leu Ala  Glu Leu Cys Glu Asn  Asp Tyr Pro 
    1010                 1015                 1020             


Asp Val  Leu Lys Phe Pro Asp  Glu Leu Ala His Val  Glu Lys Ala 
    1025                 1030                 1035             


Ser Arg  Val Ser Ala Glu Asn  Leu Gln Lys Asn Leu  Asp Gln Met 
    1040                 1045                 1050             


Lys Lys  Gln Ile Ser Asp Val  Glu Arg Asp Val Gln  Asn Phe Pro 
    1055                 1060                 1065             


Ala Ala  Thr Asp Glu Lys Asp  Lys Phe Val Glu Lys  Met Thr Ser 
    1070                 1075                 1080             


Phe Val  Lys Asp Ala Gln Glu  Gln Tyr Asn Lys Leu  Arg Met Met 
    1085                 1090                 1095             


His Ser  Asn Met Glu Thr Leu  Tyr Lys Glu Leu Gly  Glu Tyr Phe 
    1100                 1105                 1110             


Leu Phe  Asp Pro Lys Lys Leu  Ser Val Glu Glu Phe  Phe Met Asp 
    1115                 1120                 1125             


Leu His  Asn Phe Arg Asn Met  Phe Leu Gln Ala Val  Lys Glu Asn 
    1130                 1135                 1140             


Gln Lys  Arg Arg Glu Thr Glu  Glu Lys Met Arg Arg  Ala Lys Leu 
    1145                 1150                 1155             


Ala Lys  Glu Lys Ala Glu Lys  Glu Arg Leu Glu Lys  Gln Gln Lys 
    1160                 1165                 1170             


Arg Glu  Gln Leu Ile Asp Met  Asn Ala Glu Gly Asp  Glu Thr Gly 
    1175                 1180                 1185             


Val Met  Asp Ser Leu Leu Glu  Ala Leu Gln Ser Gly  Ala Ala Phe 
    1190                 1195                 1200             


Arg Arg  Lys Arg Gly Pro Arg  Gln Ala Asn Arg Lys  Ala Gly Cys 
    1205                 1210                 1215             


Ala Val  Thr Ser Leu Leu Ala  Ser Glu Leu Thr Lys  Asp Asp Ala 
    1220                 1225                 1230             


Met Ala  Ala Val Pro Ala Lys  Val Ser Lys Asn Ser  Glu Thr Phe 
    1235                 1240                 1245             


Pro Thr  Ile Leu Glu Glu Ala  Lys Glu Leu Val Gly  Arg Ala Ser 
    1250                 1255                 1260             


<210>  1517
<211>  437
<212>  PRT
<213>  Homo sapiens

<400>  1517

Met Ala Ala Gly Thr Leu Tyr Thr Tyr Pro Glu Asn Trp Arg Ala Phe 
1               5                   10                  15      


Lys Ala Leu Ile Ala Ala Gln Tyr Ser Gly Ala Gln Val Arg Val Leu 
            20                  25                  30          


Ser Ala Pro Pro His Phe His Phe Gly Gln Thr Asn Arg Thr Pro Glu 
        35                  40                  45              


Phe Leu Arg Lys Phe Pro Ala Gly Lys Val Pro Ala Phe Glu Gly Asp 
    50                  55                  60                  


Asp Gly Phe Cys Val Phe Glu Ser Asn Ala Ile Ala Tyr Tyr Val Ser 
65                  70                  75                  80  


Asn Glu Glu Leu Arg Gly Ser Thr Pro Glu Ala Ala Ala Gln Val Val 
                85                  90                  95      


Gln Trp Val Ser Phe Ala Asp Ser Asp Ile Val Pro Pro Ala Ser Thr 
            100                 105                 110         


Trp Val Phe Pro Thr Leu Gly Ile Met His His Asn Lys Gln Ala Thr 
        115                 120                 125             


Glu Asn Ala Lys Glu Glu Val Arg Arg Ile Leu Gly Leu Leu Asp Ala 
    130                 135                 140                 


Tyr Leu Lys Thr Arg Thr Phe Leu Val Gly Glu Arg Val Thr Leu Ala 
145                 150                 155                 160 


Asp Ile Thr Val Val Cys Thr Leu Leu Trp Leu Tyr Lys Gln Val Leu 
                165                 170                 175     


Glu Pro Ser Phe Arg Gln Ala Phe Pro Asn Thr Asn Arg Trp Phe Leu 
            180                 185                 190         


Thr Cys Ile Asn Gln Pro Gln Phe Arg Ala Val Leu Gly Glu Val Lys 
        195                 200                 205             


Leu Cys Glu Lys Met Ala Gln Phe Asp Ala Lys Lys Phe Ala Glu Thr 
    210                 215                 220                 


Gln Pro Lys Lys Asp Thr Pro Arg Lys Glu Lys Gly Ser Arg Glu Glu 
225                 230                 235                 240 


Lys Gln Lys Pro Gln Ala Glu Arg Lys Glu Glu Lys Lys Ala Ala Ala 
                245                 250                 255     


Pro Ala Pro Glu Glu Glu Met Asp Glu Cys Glu Gln Ala Leu Ala Ala 
            260                 265                 270         


Glu Pro Lys Ala Lys Asp Pro Phe Ala His Leu Pro Lys Ser Thr Phe 
        275                 280                 285             


Val Leu Asp Glu Phe Lys Arg Lys Tyr Ser Asn Glu Asp Thr Leu Ser 
    290                 295                 300                 


Val Ala Leu Pro Tyr Phe Trp Glu His Phe Asp Lys Asp Gly Trp Ser 
305                 310                 315                 320 


Leu Trp Tyr Ser Glu Tyr Arg Phe Pro Glu Glu Leu Thr Gln Thr Phe 
                325                 330                 335     


Met Ser Cys Asn Leu Ile Thr Gly Met Phe Gln Arg Leu Asp Lys Leu 
            340                 345                 350         


Arg Lys Asn Ala Phe Ala Ser Val Ile Leu Phe Gly Thr Asn Asn Ser 
        355                 360                 365             


Ser Ser Ile Ser Gly Val Trp Val Phe Arg Gly Gln Glu Leu Ala Phe 
    370                 375                 380                 


Pro Leu Ser Pro Asp Trp Gln Val Asp Tyr Glu Ser Tyr Thr Trp Arg 
385                 390                 395                 400 


Lys Leu Asp Pro Gly Ser Glu Glu Thr Gln Thr Leu Val Arg Glu Tyr 
                405                 410                 415     


Phe Ser Trp Glu Gly Ala Phe Gln His Val Gly Lys Ala Phe Asn Gln 
            420                 425                 430         


Gly Lys Ile Phe Lys 
        435         


<210>  1518
<211>  406
<212>  PRT
<213>  Homo sapiens

<400>  1518

Met Ser Ala Ser Gln Asp Ser Arg Ser Arg Asp Asn Gly Pro Asp Gly 
1               5                   10                  15      


Met Glu Pro Glu Gly Val Ile Glu Ser Asn Trp Asn Glu Ile Val Asp 
            20                  25                  30          


Ser Phe Asp Asp Met Asn Leu Ser Glu Ser Leu Leu Arg Gly Ile Tyr 
        35                  40                  45              


Ala Tyr Gly Phe Glu Lys Pro Ser Ala Ile Gln Gln Arg Ala Ile Leu 
    50                  55                  60                  


Pro Cys Ile Lys Gly Tyr Asp Val Ile Ala Gln Ala Gln Ser Gly Thr 
65                  70                  75                  80  


Gly Lys Thr Ala Thr Phe Ala Ile Ser Ile Leu Gln Gln Ile Glu Leu 
                85                  90                  95      


Asp Leu Lys Ala Thr Gln Ala Leu Val Leu Ala Pro Thr Arg Glu Leu 
            100                 105                 110         


Ala Gln Gln Ile Gln Lys Val Val Met Ala Leu Gly Asp Tyr Met Gly 
        115                 120                 125             


Ala Ser Cys His Ala Cys Ile Gly Gly Thr Asn Val Arg Ala Glu Val 
    130                 135                 140                 


Gln Lys Leu Gln Met Glu Ala Pro His Ile Ile Val Gly Thr Pro Gly 
145                 150                 155                 160 


Arg Val Phe Asp Met Leu Asn Arg Arg Tyr Leu Ser Pro Lys Tyr Ile 
                165                 170                 175     


Lys Met Phe Val Leu Asp Glu Ala Asp Glu Met Leu Ser Arg Gly Phe 
            180                 185                 190         


Lys Asp Gln Ile Tyr Asp Ile Phe Gln Lys Leu Asn Ser Asn Thr Gln 
        195                 200                 205             


Val Val Leu Leu Ser Ala Thr Met Pro Ser Asp Val Leu Glu Val Thr 
    210                 215                 220                 


Lys Lys Phe Met Arg Asp Pro Ile Arg Ile Leu Val Lys Lys Glu Glu 
225                 230                 235                 240 


Leu Thr Leu Glu Gly Ile Arg Gln Phe Tyr Ile Asn Val Glu Arg Glu 
                245                 250                 255     


Glu Trp Lys Leu Asp Thr Leu Cys Asp Leu Tyr Glu Thr Leu Thr Ile 
            260                 265                 270         


Thr Gln Ala Val Ile Phe Ile Asn Thr Arg Arg Lys Val Asp Trp Leu 
        275                 280                 285             


Thr Glu Lys Met His Ala Arg Asp Phe Thr Val Ser Ala Met His Gly 
    290                 295                 300                 


Asp Met Asp Gln Lys Glu Arg Asp Val Ile Met Arg Glu Phe Arg Ser 
305                 310                 315                 320 


Gly Ser Ser Arg Val Leu Ile Thr Thr Asp Leu Leu Ala Arg Gly Ile 
                325                 330                 335     


Asp Val Gln Gln Val Ser Leu Val Ile Asn Tyr Asp Leu Pro Thr Asn 
            340                 345                 350         


Arg Glu Asn Tyr Ile His Arg Ile Gly Arg Gly Gly Arg Phe Gly Arg 
        355                 360                 365             


Lys Gly Val Ala Ile Asn Met Val Thr Glu Glu Asp Lys Arg Thr Leu 
    370                 375                 380                 


Arg Asp Ile Glu Thr Phe Tyr Asn Thr Ser Ile Glu Glu Met Pro Leu 
385                 390                 395                 400 


Asn Val Ala Asp Leu Ile 
                405     


<210>  1519
<211>  108
<212>  PRT
<213>  Homo sapiens

<400>  1519

Met Gly Val Gln Val Glu Thr Ile Ser Pro Gly Asp Gly Arg Thr Phe 
1               5                   10                  15      


Pro Lys Arg Gly Gln Thr Cys Val Val His Tyr Thr Gly Met Leu Glu 
            20                  25                  30          


Asp Gly Lys Lys Phe Asp Ser Ser Arg Asp Arg Asn Lys Pro Phe Lys 
        35                  40                  45              


Phe Met Leu Gly Lys Gln Glu Val Ile Arg Gly Trp Glu Glu Gly Val 
    50                  55                  60                  


Ala Gln Met Ser Val Gly Gln Arg Ala Lys Leu Thr Ile Ser Pro Asp 
65                  70                  75                  80  


Tyr Ala Tyr Gly Ala Thr Gly His Pro Gly Ile Ile Pro Pro His Ala 
                85                  90                  95      


Thr Leu Val Phe Asp Val Glu Leu Leu Lys Leu Glu 
            100                 105             


<210>  1520
<211>  183
<212>  PRT
<213>  Homo sapiens

<400>  1520

Met Thr Thr Ala Ser Thr Ser Gln Val Arg Gln Asn Tyr His Gln Asp 
1               5                   10                  15      


Ser Glu Ala Ala Ile Asn Arg Gln Ile Asn Leu Glu Leu Tyr Ala Ser 
            20                  25                  30          


Tyr Val Tyr Leu Ser Met Ser Tyr Tyr Phe Asp Arg Asp Asp Val Ala 
        35                  40                  45              


Leu Lys Asn Phe Ala Lys Tyr Phe Leu His Gln Ser His Glu Glu Arg 
    50                  55                  60                  


Glu His Ala Glu Lys Leu Met Lys Leu Gln Asn Gln Arg Gly Gly Arg 
65                  70                  75                  80  


Ile Phe Leu Gln Asp Ile Lys Glu Pro Asp Cys Asp Asp Trp Glu Ser 
                85                  90                  95      


Gly Gln Asn Ala Met Glu Cys Ala Leu His Leu Glu Lys Asn Val Asn 
            100                 105                 110         


Gln Ser Leu Leu Glu Leu His Lys Leu Ala Thr Asp Lys Asn Asp Pro 
        115                 120                 125             


His Leu Cys Asp Phe Ile Glu Thr His Tyr Leu Asn Glu Gln Val Lys 
    130                 135                 140                 


Ala Ile Lys Glu Leu Gly Asp His Val Thr Asn Leu Arg Lys Met Gly 
145                 150                 155                 160 


Ala Pro Glu Ser Gly Leu Ala Glu Tyr Leu Phe Asp Lys His Thr Leu 
                165                 170                 175     


Gly Asp Ser Asp Asn Glu Ser 
            180             


<210>  1521
<211>  335
<212>  PRT
<213>  Homo sapiens

<400>  1521

Met Gly Lys Val Lys Val Gly Val Asn Gly Phe Gly Arg Ile Gly Arg 
1               5                   10                  15      


Leu Val Thr Arg Ala Ala Phe Asn Ser Gly Lys Val Asp Ile Val Ala 
            20                  25                  30          


Ile Asn Asp Pro Phe Ile Asp Leu Asn Tyr Met Val Tyr Met Phe Gln 
        35                  40                  45              


Tyr Asp Ser Thr His Gly Lys Phe His Gly Thr Val Lys Ala Glu Asn 
    50                  55                  60                  


Gly Lys Leu Val Ile Asn Gly Asn Pro Ile Thr Ile Phe Gln Glu Arg 
65                  70                  75                  80  


Asp Pro Ser Lys Ile Lys Trp Gly Asp Ala Gly Ala Glu Tyr Val Val 
                85                  90                  95      


Glu Ser Thr Gly Val Phe Thr Thr Met Glu Lys Ala Gly Ala His Leu 
            100                 105                 110         


Gln Gly Gly Ala Lys Arg Val Ile Ile Ser Ala Pro Ser Ala Asp Ala 
        115                 120                 125             


Pro Met Phe Val Met Gly Val Asn His Glu Lys Tyr Asp Asn Ser Leu 
    130                 135                 140                 


Lys Ile Ile Ser Asn Ala Ser Cys Thr Thr Asn Cys Leu Ala Pro Leu 
145                 150                 155                 160 


Ala Lys Val Ile His Asp Asn Phe Gly Ile Val Glu Gly Leu Met Thr 
                165                 170                 175     


Thr Val His Ala Ile Thr Ala Thr Gln Lys Thr Val Asp Gly Pro Ser 
            180                 185                 190         


Gly Lys Leu Trp Arg Asp Gly Arg Gly Ala Leu Gln Asn Ile Ile Pro 
        195                 200                 205             


Ala Ser Thr Gly Ala Ala Lys Ala Val Gly Lys Val Ile Pro Glu Leu 
    210                 215                 220                 


Asn Gly Lys Leu Thr Gly Met Ala Phe Arg Val Pro Thr Ala Asn Val 
225                 230                 235                 240 


Ser Val Val Asp Leu Thr Cys Arg Leu Glu Lys Pro Ala Lys Tyr Asp 
                245                 250                 255     


Asp Ile Lys Lys Val Val Lys Gln Ala Ser Glu Gly Pro Leu Lys Gly 
            260                 265                 270         


Ile Leu Gly Tyr Thr Glu His Gln Val Val Ser Ser Asp Phe Asn Ser 
        275                 280                 285             


Asp Thr His Ser Ser Thr Phe Asp Ala Gly Ala Gly Ile Ala Leu Asn 
    290                 295                 300                 


Asp His Phe Val Lys Leu Ile Ser Trp Tyr Asp Asn Glu Phe Gly Tyr 
305                 310                 315                 320 


Ser Asn Arg Val Val Asp Leu Met Ala His Met Ala Ser Lys Glu 
                325                 330                 335 


<210>  1522
<211>  349
<212>  PRT
<213>  Homo sapiens

<400>  1522

Met Ala Ser Lys Lys Val Cys Ile Val Gly Ser Gly Asn Trp Gly Ser 
1               5                   10                  15      


Ala Ile Ala Lys Ile Val Gly Gly Asn Ala Ala Gln Leu Ala Gln Phe 
            20                  25                  30          


Asp Pro Arg Val Thr Met Trp Val Phe Glu Glu Asp Ile Gly Gly Lys 
        35                  40                  45              


Lys Leu Thr Glu Ile Ile Asn Thr Gln His Glu Asn Val Lys Tyr Leu 
    50                  55                  60                  


Pro Gly His Lys Leu Pro Pro Asn Val Val Ala Val Pro Asp Val Val 
65                  70                  75                  80  


Gln Ala Ala Glu Asp Ala Asp Ile Leu Ile Phe Val Val Pro His Gln 
                85                  90                  95      


Phe Ile Gly Lys Ile Cys Asp Gln Leu Lys Gly His Leu Lys Ala Asn 
            100                 105                 110         


Ala Thr Gly Ile Ser Leu Ile Lys Gly Val Asp Glu Gly Pro Asn Gly 
        115                 120                 125             


Leu Lys Leu Ile Ser Glu Val Ile Gly Glu Arg Leu Gly Ile Pro Met 
    130                 135                 140                 


Ser Val Leu Met Gly Ala Asn Ile Ala Ser Glu Val Ala Asp Glu Lys 
145                 150                 155                 160 


Phe Cys Glu Thr Thr Ile Gly Cys Lys Asp Pro Ala Gln Gly Gln Leu 
                165                 170                 175     


Leu Lys Glu Leu Met Gln Thr Pro Asn Phe Arg Ile Thr Val Val Gln 
            180                 185                 190         


Glu Val Asp Thr Val Glu Ile Cys Gly Ala Leu Lys Asn Val Val Ala 
        195                 200                 205             


Val Gly Ala Gly Phe Cys Asp Gly Leu Gly Phe Gly Asp Asn Thr Lys 
    210                 215                 220                 


Ala Ala Val Ile Arg Leu Gly Leu Met Glu Met Ile Ala Phe Ala Lys 
225                 230                 235                 240 


Leu Phe Cys Ser Gly Pro Val Ser Ser Ala Thr Phe Leu Glu Ser Cys 
                245                 250                 255     


Gly Val Ala Asp Leu Ile Thr Thr Cys Tyr Gly Gly Arg Asn Arg Lys 
            260                 265                 270         


Val Ala Glu Ala Phe Ala Arg Thr Gly Lys Ser Ile Glu Gln Leu Glu 
        275                 280                 285             


Lys Glu Leu Leu Asn Gly Gln Lys Leu Gln Gly Pro Glu Thr Ala Arg 
    290                 295                 300                 


Glu Leu Tyr Ser Ile Leu Gln His Lys Gly Leu Val Asp Lys Phe Pro 
305                 310                 315                 320 


Leu Phe Met Ala Val Tyr Lys Val Cys Tyr Glu Gly Gln Pro Val Gly 
                325                 330                 335     


Glu Phe Ile His Cys Leu Gln Asn His Pro Glu His Met 
            340                 345                 


<210>  1523
<211>  736
<212>  PRT
<213>  Homo sapiens

<400>  1523

Met Gly Ser Pro Leu Arg Phe Asp Gly Arg Val Val Leu Val Thr Gly 
1               5                   10                  15      


Ala Gly Ala Gly Leu Gly Arg Ala Tyr Ala Leu Ala Phe Ala Glu Arg 
            20                  25                  30          


Gly Ala Leu Val Val Val Asn Asp Leu Gly Gly Asp Phe Lys Gly Val 
        35                  40                  45              


Gly Lys Gly Ser Leu Ala Ala Asp Lys Val Val Glu Glu Ile Arg Arg 
    50                  55                  60                  


Arg Gly Gly Lys Ala Val Ala Asn Tyr Asp Ser Val Glu Glu Gly Glu 
65                  70                  75                  80  


Lys Val Val Lys Thr Ala Leu Asp Ala Phe Gly Arg Ile Asp Val Val 
                85                  90                  95      


Val Asn Asn Ala Gly Ile Leu Arg Asp Arg Ser Phe Ala Arg Ile Ser 
            100                 105                 110         


Asp Glu Asp Trp Asp Ile Ile His Arg Val His Leu Arg Gly Ser Phe 
        115                 120                 125             


Gln Val Thr Arg Ala Ala Trp Glu His Met Lys Lys Gln Lys Tyr Gly 
    130                 135                 140                 


Arg Ile Ile Met Thr Ser Ser Ala Ser Gly Ile Tyr Gly Asn Phe Gly 
145                 150                 155                 160 


Gln Ala Asn Tyr Ser Ala Ala Lys Leu Gly Leu Leu Gly Leu Ala Asn 
                165                 170                 175     


Ser Leu Ala Ile Glu Gly Arg Lys Ser Asn Ile His Cys Asn Thr Ile 
            180                 185                 190         


Ala Pro Asn Ala Gly Ser Arg Met Thr Gln Thr Val Met Pro Glu Asp 
        195                 200                 205             


Leu Val Glu Ala Leu Lys Pro Glu Tyr Val Ala Pro Leu Val Leu Trp 
    210                 215                 220                 


Leu Cys His Glu Ser Cys Glu Glu Asn Gly Gly Leu Phe Glu Val Gly 
225                 230                 235                 240 


Ala Gly Trp Ile Gly Lys Leu Arg Trp Glu Arg Thr Leu Gly Ala Ile 
                245                 250                 255     


Val Arg Gln Lys Asn His Pro Met Thr Pro Glu Ala Val Lys Ala Asn 
            260                 265                 270         


Trp Lys Lys Ile Cys Asp Phe Glu Asn Ala Ser Lys Pro Gln Ser Ile 
        275                 280                 285             


Gln Glu Ser Thr Gly Ser Ile Ile Glu Val Leu Ser Lys Ile Asp Ser 
    290                 295                 300                 


Glu Gly Gly Val Ser Ala Asn His Thr Ser Arg Ala Thr Ser Thr Ala 
305                 310                 315                 320 


Thr Ser Gly Phe Ala Gly Ala Ile Gly Gln Lys Leu Pro Pro Phe Ser 
                325                 330                 335     


Tyr Ala Tyr Thr Glu Leu Glu Ala Ile Met Tyr Ala Leu Gly Val Gly 
            340                 345                 350         


Ala Ser Ile Lys Asp Pro Lys Asp Leu Lys Phe Ile Tyr Glu Gly Ser 
        355                 360                 365             


Ser Asp Phe Ser Cys Leu Pro Thr Phe Gly Val Ile Ile Gly Gln Lys 
    370                 375                 380                 


Ser Met Met Gly Gly Gly Leu Ala Glu Ile Pro Gly Leu Ser Ile Asn 
385                 390                 395                 400 


Phe Ala Lys Val Leu His Gly Glu Gln Tyr Leu Glu Leu Tyr Lys Pro 
                405                 410                 415     


Leu Pro Arg Ala Gly Lys Leu Lys Cys Glu Ala Val Val Ala Asp Val 
            420                 425                 430         


Leu Asp Lys Gly Ser Gly Val Val Ile Ile Met Asp Val Tyr Ser Tyr 
        435                 440                 445             


Ser Glu Lys Glu Leu Ile Cys His Asn Gln Phe Ser Leu Phe Leu Val 
    450                 455                 460                 


Gly Ser Gly Gly Phe Gly Gly Lys Arg Thr Ser Asp Lys Val Lys Val 
465                 470                 475                 480 


Ala Val Ala Ile Pro Asn Arg Pro Pro Asp Ala Val Leu Thr Asp Thr 
                485                 490                 495     


Thr Ser Leu Asn Gln Ala Ala Leu Tyr Arg Leu Ser Gly Asp Trp Asn 
            500                 505                 510         


Pro Leu His Ile Asp Pro Asn Phe Ala Ser Leu Ala Gly Phe Asp Lys 
        515                 520                 525             


Pro Ile Leu His Gly Leu Cys Thr Phe Gly Phe Ser Ala Arg Arg Val 
    530                 535                 540                 


Leu Gln Gln Phe Ala Asp Asn Asp Val Ser Arg Phe Lys Ala Ile Lys 
545                 550                 555                 560 


Ala Arg Phe Ala Lys Pro Val Tyr Pro Gly Gln Thr Leu Gln Thr Glu 
                565                 570                 575     


Met Trp Lys Glu Gly Asn Arg Ile His Phe Gln Thr Lys Val Gln Glu 
            580                 585                 590         


Thr Gly Asp Ile Val Ile Ser Asn Ala Tyr Val Asp Leu Ala Pro Thr 
        595                 600                 605             


Ser Gly Thr Ser Ala Lys Thr Pro Ser Glu Gly Gly Lys Leu Gln Ser 
    610                 615                 620                 


Thr Phe Val Phe Glu Glu Ile Gly Arg Arg Leu Lys Asp Ile Gly Pro 
625                 630                 635                 640 


Glu Val Val Lys Lys Val Asn Ala Val Phe Glu Trp His Ile Thr Lys 
                645                 650                 655     


Gly Gly Asn Ile Gly Ala Lys Trp Thr Ile Asp Leu Lys Ser Gly Ser 
            660                 665                 670         


Gly Lys Val Tyr Gln Gly Pro Ala Lys Gly Ala Ala Asp Thr Thr Ile 
        675                 680                 685             


Ile Leu Ser Asp Glu Asp Phe Met Glu Val Val Leu Gly Lys Leu Asp 
    690                 695                 700                 


Pro Gln Lys Ala Phe Phe Ser Gly Arg Leu Lys Ala Arg Gly Asn Ile 
705                 710                 715                 720 


Met Leu Ser Gln Lys Leu Gln Met Ile Leu Lys Asp Tyr Ala Lys Leu 
                725                 730                 735     


<210>  1524
<211>  641
<212>  PRT
<213>  Homo sapiens

<400>  1524

Met Ala Thr Ala Lys Gly Ile Ala Ile Gly Ile Asp Leu Gly Thr Thr 
1               5                   10                  15      


Tyr Ser Cys Val Gly Val Phe Gln His Gly Lys Val Glu Ile Ile Ala 
            20                  25                  30          


Asn Asp Gln Gly Asn Arg Thr Thr Pro Ser Tyr Val Ala Phe Thr Asp 
        35                  40                  45              


Thr Glu Arg Leu Ile Gly Asp Ala Ala Lys Asn Gln Val Ala Met Asn 
    50                  55                  60                  


Pro Gln Asn Thr Val Phe Asp Ala Lys Arg Leu Ile Gly Arg Lys Phe 
65                  70                  75                  80  


Asn Asp Pro Val Val Gln Ala Asp Met Lys Leu Trp Pro Phe Gln Val 
                85                  90                  95      


Ile Asn Glu Gly Gly Lys Pro Lys Val Leu Val Ser Tyr Lys Gly Glu 
            100                 105                 110         


Asn Lys Ala Phe Tyr Pro Glu Glu Ile Ser Ser Met Val Leu Thr Lys 
        115                 120                 125             


Leu Lys Glu Thr Ala Glu Ala Phe Leu Gly His Pro Val Thr Asn Ala 
    130                 135                 140                 


Val Ile Thr Val Pro Ala Tyr Phe Asn Asp Ser Gln Arg Gln Ala Thr 
145                 150                 155                 160 


Lys Asp Ala Gly Val Ile Ala Gly Leu Asn Val Leu Arg Ile Ile Asn 
                165                 170                 175     


Glu Pro Thr Ala Ala Ala Ile Ala Tyr Gly Leu Asp Lys Gly Gly Gln 
            180                 185                 190         


Gly Glu Arg His Val Leu Ile Phe Asp Leu Gly Gly Gly Thr Phe Asp 
        195                 200                 205             


Val Ser Ile Leu Thr Ile Asp Asp Gly Ile Phe Glu Val Lys Ala Thr 
    210                 215                 220                 


Ala Gly Asp Thr His Leu Gly Gly Glu Asp Phe Asp Asn Arg Leu Val 
225                 230                 235                 240 


Ser His Phe Val Glu Glu Phe Lys Arg Lys His Lys Lys Asp Ile Ser 
                245                 250                 255     


Gln Asn Lys Arg Ala Val Arg Arg Leu Arg Thr Ala Cys Glu Arg Ala 
            260                 265                 270         


Lys Arg Thr Leu Ser Ser Ser Thr Gln Ala Asn Leu Glu Ile Asp Ser 
        275                 280                 285             


Leu Tyr Glu Gly Ile Asp Phe Tyr Thr Ser Ile Thr Arg Ala Arg Phe 
    290                 295                 300                 


Glu Glu Leu Cys Ala Asp Leu Phe Arg Gly Thr Leu Glu Pro Val Glu 
305                 310                 315                 320 


Lys Ala Leu Arg Asp Ala Lys Met Asp Lys Ala Lys Ile His Asp Ile 
                325                 330                 335     


Val Leu Val Gly Gly Ser Thr Arg Ile Pro Lys Val Gln Arg Leu Leu 
            340                 345                 350         


Gln Asp Tyr Phe Asn Gly Arg Asp Leu Asn Lys Ser Ile Asn Pro Asp 
        355                 360                 365             


Glu Ala Val Ala Tyr Gly Ala Ala Val Gln Ala Ala Ile Leu Met Gly 
    370                 375                 380                 


Asp Lys Ser Glu Lys Val Gln Asp Leu Leu Leu Leu Asp Val Ala Pro 
385                 390                 395                 400 


Leu Ser Leu Gly Leu Glu Thr Ala Gly Gly Val Met Thr Ala Leu Met 
                405                 410                 415     


Lys Arg Asn Ser Thr Ile Pro Thr Lys Gln Thr Gln Ile Phe Thr Thr 
            420                 425                 430         


Tyr Ser Asp Asn Gln Pro Gly Val Leu Ile Gln Val Tyr Glu Gly Glu 
        435                 440                 445             


Arg Ala Met Thr Lys Asp Asn Asn Leu Leu Gly Arg Phe Asp Leu Thr 
    450                 455                 460                 


Gly Ile Pro Pro Ala Pro Arg Gly Val Pro Gln Ile Glu Val Thr Phe 
465                 470                 475                 480 


Asp Ile Asp Ala Asn Gly Ile Leu Asn Val Thr Ala Met Asp Lys Ser 
                485                 490                 495     


Thr Gly Lys Val Asn Lys Ile Thr Ile Ala Asn Asp Lys Gly Arg Leu 
            500                 505                 510         


Ser Lys Glu Glu Ile Glu Arg Met Val Leu Asp Ala Glu Lys Tyr Lys 
        515                 520                 525             


Ala Glu Asp Glu Val Gln Arg Glu Lys Ile Ala Ala Lys Asn Ala Leu 
    530                 535                 540                 


Glu Ser Tyr Ala Phe Asn Met Lys Ser Val Val Ser Asp Glu Gly Leu 
545                 550                 555                 560 


Lys Gly Lys Ile Ser Glu Ser Asp Lys Asn Lys Ile Leu Asp Lys Cys 
                565                 570                 575     


Asn Glu Leu Leu Ser Trp Leu Glu Val Asn Gln Leu Ala Glu Lys Asp 
            580                 585                 590         


Glu Phe Asp His Lys Arg Lys Glu Leu Glu Gln Met Cys Asn Pro Ile 
        595                 600                 605             


Ile Thr Lys Leu Tyr Gln Gly Gly Cys Thr Gly Pro Ala Cys Gly Thr 
    610                 615                 620                 


Gly Tyr Val Pro Gly Arg Pro Ala Thr Gly Pro Thr Ile Glu Glu Val 
625                 630                 635                 640 


Asp 
    


<210>  1525
<211>  646
<212>  PRT
<213>  Homo sapiens

<400>  1525

Met Ser Lys Gly Pro Ala Val Gly Ile Asp Leu Gly Thr Thr Tyr Ser 
1               5                   10                  15      


Cys Val Gly Val Phe Gln His Gly Lys Val Glu Ile Ile Ala Asn Asp 
            20                  25                  30          


Gln Gly Asn Arg Thr Thr Pro Ser Tyr Val Ala Phe Thr Asp Thr Glu 
        35                  40                  45              


Arg Leu Ile Gly Asp Ala Ala Lys Asn Gln Val Ala Met Asn Pro Thr 
    50                  55                  60                  


Asn Thr Val Phe Asp Ala Lys Arg Leu Ile Gly Arg Arg Phe Asp Asp 
65                  70                  75                  80  


Ala Val Val Gln Ser Asp Met Lys His Trp Pro Phe Met Val Val Asn 
                85                  90                  95      


Asp Ala Gly Arg Pro Lys Val Gln Val Glu Tyr Lys Gly Glu Thr Lys 
            100                 105                 110         


Ser Phe Tyr Pro Glu Glu Val Ser Ser Met Val Leu Thr Lys Met Lys 
        115                 120                 125             


Glu Ile Ala Glu Ala Tyr Leu Gly Lys Thr Val Thr Asn Ala Val Val 
    130                 135                 140                 


Thr Val Pro Ala Tyr Phe Asn Asp Ser Gln Arg Gln Ala Thr Lys Asp 
145                 150                 155                 160 


Ala Gly Thr Ile Ala Gly Leu Asn Val Leu Arg Ile Ile Asn Glu Pro 
                165                 170                 175     


Thr Ala Ala Ala Ile Ala Tyr Gly Leu Asp Lys Lys Val Gly Ala Glu 
            180                 185                 190         


Arg Asn Val Leu Ile Phe Asp Leu Gly Gly Gly Thr Phe Asp Val Ser 
        195                 200                 205             


Ile Leu Thr Ile Glu Asp Gly Ile Phe Glu Val Lys Ser Thr Ala Gly 
    210                 215                 220                 


Asp Thr His Leu Gly Gly Glu Asp Phe Asp Asn Arg Met Val Asn His 
225                 230                 235                 240 


Phe Ile Ala Glu Phe Lys Arg Lys His Lys Lys Asp Ile Ser Glu Asn 
                245                 250                 255     


Lys Arg Ala Val Arg Arg Leu Arg Thr Ala Cys Glu Arg Ala Lys Arg 
            260                 265                 270         


Thr Leu Ser Ser Ser Thr Gln Ala Ser Ile Glu Ile Asp Ser Leu Tyr 
        275                 280                 285             


Glu Gly Ile Asp Phe Tyr Thr Ser Ile Thr Arg Ala Arg Phe Glu Glu 
    290                 295                 300                 


Leu Asn Ala Asp Leu Phe Arg Gly Thr Leu Asp Pro Val Glu Lys Ala 
305                 310                 315                 320 


Leu Arg Asp Ala Lys Leu Asp Lys Ser Gln Ile His Asp Ile Val Leu 
                325                 330                 335     


Val Gly Gly Ser Thr Arg Ile Pro Lys Ile Gln Lys Leu Leu Gln Asp 
            340                 345                 350         


Phe Phe Asn Gly Lys Glu Leu Asn Lys Ser Ile Asn Pro Asp Glu Ala 
        355                 360                 365             


Val Ala Tyr Gly Ala Ala Val Gln Ala Ala Ile Leu Ser Gly Asp Lys 
    370                 375                 380                 


Ser Glu Asn Val Gln Asp Leu Leu Leu Leu Asp Val Thr Pro Leu Ser 
385                 390                 395                 400 


Leu Gly Ile Glu Thr Ala Gly Gly Val Met Thr Val Leu Ile Lys Arg 
                405                 410                 415     


Asn Thr Thr Ile Pro Thr Lys Gln Thr Gln Thr Phe Thr Thr Tyr Ser 
            420                 425                 430         


Asp Asn Gln Pro Gly Val Leu Ile Gln Val Tyr Glu Gly Glu Arg Ala 
        435                 440                 445             


Met Thr Lys Asp Asn Asn Leu Leu Gly Lys Phe Glu Leu Thr Gly Ile 
    450                 455                 460                 


Pro Pro Ala Pro Arg Gly Val Pro Gln Ile Glu Val Thr Phe Asp Ile 
465                 470                 475                 480 


Asp Ala Asn Gly Ile Leu Asn Val Ser Ala Val Asp Lys Ser Thr Gly 
                485                 490                 495     


Lys Glu Asn Lys Ile Thr Ile Thr Asn Asp Lys Gly Arg Leu Ser Lys 
            500                 505                 510         


Glu Asp Ile Glu Arg Met Val Gln Glu Ala Glu Lys Tyr Lys Ala Glu 
        515                 520                 525             


Asp Glu Lys Gln Arg Asp Lys Val Ser Ser Lys Asn Ser Leu Glu Ser 
    530                 535                 540                 


Tyr Ala Phe Asn Met Lys Ala Thr Val Glu Asp Glu Lys Leu Gln Gly 
545                 550                 555                 560 


Lys Ile Asn Asp Glu Asp Lys Gln Lys Ile Leu Asp Lys Cys Asn Glu 
                565                 570                 575     


Ile Ile Asn Trp Leu Asp Lys Asn Gln Thr Ala Glu Lys Glu Glu Phe 
            580                 585                 590         


Glu His Gln Gln Lys Glu Leu Glu Lys Val Cys Asn Pro Ile Ile Thr 
        595                 600                 605             


Lys Leu Tyr Gln Ser Ala Gly Gly Met Pro Gly Gly Met Pro Gly Gly 
    610                 615                 620                 


Phe Pro Gly Gly Gly Ala Pro Pro Ser Gly Gly Ala Ser Ser Gly Pro 
625                 630                 635                 640 


Thr Ile Glu Glu Val Asp 
                645     


<210>  1526
<211>  734
<212>  PRT
<213>  Homo sapiens

<400>  1526

Met Ser Gly Phe Asp Asp Pro Gly Ile Phe Tyr Ser Asp Ser Phe Gly 
1               5                   10                  15      


Gly Asp Ala Gln Ala Asp Glu Gly Gln Ala Arg Lys Ser Gln Leu Gln 
            20                  25                  30          


Arg Arg Phe Lys Glu Phe Leu Arg Gln Tyr Arg Val Gly Thr Asp Arg 
        35                  40                  45              


Thr Gly Phe Thr Phe Lys Tyr Arg Asp Glu Leu Lys Arg His Tyr Asn 
    50                  55                  60                  


Leu Gly Glu Tyr Trp Ile Glu Val Glu Met Glu Asp Leu Ala Ser Phe 
65                  70                  75                  80  


Asp Glu Asp Leu Ala Asp Tyr Leu Tyr Lys Gln Pro Ala Glu His Leu 
                85                  90                  95      


Gln Leu Leu Glu Glu Ala Ala Lys Glu Val Ala Asp Glu Val Thr Arg 
            100                 105                 110         


Pro Arg Pro Ser Gly Glu Glu Val Leu Gln Asp Ile Gln Val Met Leu 
        115                 120                 125             


Lys Ser Asp Ala Ser Pro Ser Ser Ile Arg Ser Leu Lys Ser Asp Met 
    130                 135                 140                 


Met Ser His Leu Val Lys Ile Pro Gly Ile Ile Ile Ala Ala Ser Ala 
145                 150                 155                 160 


Val Arg Ala Lys Ala Thr Arg Ile Ser Ile Gln Cys Arg Ser Cys Arg 
                165                 170                 175     


Asn Thr Leu Thr Asn Ile Ala Met Arg Pro Gly Leu Glu Gly Tyr Ala 
            180                 185                 190         


Leu Pro Arg Lys Cys Asn Thr Asp Gln Ala Gly Arg Pro Lys Cys Pro 
        195                 200                 205             


Leu Asp Pro Tyr Phe Ile Met Pro Asp Lys Cys Lys Cys Val Asp Phe 
    210                 215                 220                 


Gln Thr Leu Lys Leu Gln Glu Leu Pro Asp Ala Val Pro His Gly Glu 
225                 230                 235                 240 


Met Pro Arg His Met Gln Leu Tyr Cys Asp Arg Tyr Leu Cys Asp Lys 
                245                 250                 255     


Val Val Pro Gly Asn Arg Val Thr Ile Met Gly Ile Tyr Ser Ile Lys 
            260                 265                 270         


Lys Phe Gly Leu Thr Thr Ser Arg Gly Arg Asp Arg Val Gly Val Gly 
        275                 280                 285             


Ile Arg Ser Ser Tyr Ile Arg Val Leu Gly Ile Gln Val Asp Thr Asp 
    290                 295                 300                 


Gly Ser Gly Arg Ser Phe Ala Gly Ala Val Ser Pro Gln Glu Glu Glu 
305                 310                 315                 320 


Glu Phe Arg Arg Leu Ala Ala Leu Pro Asn Val Tyr Glu Val Ile Ser 
                325                 330                 335     


Lys Ser Ile Ala Pro Ser Ile Phe Gly Gly Thr Asp Met Lys Lys Ala 
            340                 345                 350         


Ile Ala Cys Leu Leu Phe Gly Gly Ser Arg Lys Arg Leu Pro Asp Gly 
        355                 360                 365             


Leu Thr Arg Arg Gly Asp Ile Asn Leu Leu Met Leu Gly Asp Pro Gly 
    370                 375                 380                 


Thr Ala Lys Ser Gln Leu Leu Lys Phe Val Glu Lys Cys Ser Pro Ile 
385                 390                 395                 400 


Gly Val Tyr Thr Ser Gly Lys Gly Ser Ser Ala Ala Gly Leu Thr Ala 
                405                 410                 415     


Ser Val Met Arg Asp Pro Ser Ser Arg Asn Phe Ile Met Glu Gly Gly 
            420                 425                 430         


Ala Met Val Leu Ala Asp Gly Gly Val Val Cys Ile Asp Glu Phe Asp 
        435                 440                 445             


Lys Met Arg Glu Asp Asp Arg Val Ala Ile His Glu Ala Met Glu Gln 
    450                 455                 460                 


Gln Thr Ile Ser Ile Ala Lys Ala Gly Ile Thr Thr Thr Leu Asn Ser 
465                 470                 475                 480 


Arg Cys Ser Val Leu Ala Ala Ala Asn Ser Val Phe Gly Arg Trp Asp 
                485                 490                 495     


Glu Thr Lys Gly Glu Asp Asn Ile Asp Phe Met Pro Thr Ile Leu Ser 
            500                 505                 510         


Arg Phe Asp Met Ile Phe Ile Val Lys Asp Glu His Asn Glu Glu Arg 
        515                 520                 525             


Asp Val Met Leu Ala Lys His Val Ile Thr Leu His Val Ser Ala Leu 
    530                 535                 540                 


Thr Gln Thr Gln Ala Val Glu Gly Glu Ile Asp Leu Ala Lys Leu Lys 
545                 550                 555                 560 


Lys Phe Ile Ala Tyr Cys Arg Val Lys Cys Gly Pro Arg Leu Ser Ala 
                565                 570                 575     


Glu Ala Ala Glu Lys Leu Lys Asn Arg Tyr Ile Ile Met Arg Ser Gly 
            580                 585                 590         


Ala Arg Gln His Glu Arg Asp Ser Asp Arg Arg Ser Ser Ile Pro Ile 
        595                 600                 605             


Thr Val Arg Gln Leu Glu Ala Ile Val Arg Ile Ala Glu Ala Leu Ser 
    610                 615                 620                 


Lys Met Lys Leu Gln Pro Phe Ala Thr Glu Ala Asp Val Glu Glu Ala 
625                 630                 635                 640 


Leu Arg Leu Phe Gln Val Ser Thr Leu Asp Ala Ala Leu Ser Gly Thr 
                645                 650                 655     


Leu Ser Gly Val Glu Gly Phe Thr Ser Gln Glu Asp Gln Glu Met Leu 
            660                 665                 670         


Ser Arg Ile Glu Lys Gln Leu Lys Arg Arg Phe Ala Ile Gly Ser Gln 
        675                 680                 685             


Val Ser Glu His Ser Ile Ile Lys Asp Phe Thr Lys Gln Lys Tyr Pro 
    690                 695                 700                 


Glu His Ala Ile His Lys Val Leu Gln Leu Met Leu Arg Arg Gly Glu 
705                 710                 715                 720 


Ile Gln His Arg Met Gln Arg Lys Val Leu Tyr Arg Leu Lys 
                725                 730                 


<210>  1527
<211>  626
<212>  PRT
<213>  Homo sapiens

<400>  1527

Met Asp Glu Gln Glu Ala Leu Asn Ser Ile Met Asn Asp Leu Val Ala 
1               5                   10                  15      


Leu Gln Met Asn Arg Arg His Arg Met Pro Gly Tyr Glu Thr Met Lys 
            20                  25                  30          


Asn Lys Asp Thr Gly His Ser Asn Arg Gln Ser Asp Val Arg Ile Lys 
        35                  40                  45              


Phe Glu His Asn Gly Glu Arg Arg Ile Ile Ala Phe Ser Arg Pro Val 
    50                  55                  60                  


Lys Tyr Glu Asp Val Glu His Lys Val Thr Thr Val Phe Gly Gln Pro 
65                  70                  75                  80  


Leu Asp Leu His Tyr Met Asn Asn Glu Leu Ser Ile Leu Leu Lys Asn 
                85                  90                  95      


Gln Asp Asp Leu Asp Lys Ala Ile Asp Ile Leu Asp Arg Ser Ser Ser 
            100                 105                 110         


Met Lys Ser Leu Arg Ile Leu Leu Leu Ser Gln Asp Arg Asn His Asn 
        115                 120                 125             


Ser Ser Ser Pro His Ser Gly Val Ser Arg Gln Val Arg Ile Lys Ala 
    130                 135                 140                 


Ser Gln Ser Ala Gly Asp Ile Asn Thr Ile Tyr Gln Pro Pro Glu Pro 
145                 150                 155                 160 


Arg Ser Arg His Leu Ser Val Ser Ser Gln Asn Pro Gly Arg Ser Ser 
                165                 170                 175     


Pro Pro Pro Gly Tyr Val Pro Glu Arg Gln Gln His Ile Ala Arg Gln 
            180                 185                 190         


Gly Ser Tyr Thr Ser Ile Asn Ser Glu Gly Glu Phe Ile Pro Glu Thr 
        195                 200                 205             


Ser Glu Gln Cys Met Leu Asp Pro Leu Ser Ser Ala Glu Asn Ser Leu 
    210                 215                 220                 


Ser Gly Ser Cys Gln Ser Leu Asp Arg Ser Ala Asp Ser Pro Ser Phe 
225                 230                 235                 240 


Arg Lys Ser Arg Met Ser Arg Ala Gln Ser Phe Pro Asp Asn Arg Gln 
                245                 250                 255     


Glu Tyr Ser Asp Arg Glu Thr Gln Leu Tyr Asp Lys Gly Val Lys Gly 
            260                 265                 270         


Gly Thr Tyr Pro Arg Arg Tyr His Val Ser Val His His Lys Asp Tyr 
        275                 280                 285             


Ser Asp Gly Arg Arg Thr Phe Pro Arg Ile Arg Arg His Gln Gly Asn 
    290                 295                 300                 


Leu Phe Thr Leu Val Pro Ser Ser Arg Ser Leu Ser Thr Asn Gly Glu 
305                 310                 315                 320 


Asn Met Gly Leu Ala Val Gln Tyr Leu Asp Pro Arg Gly Arg Leu Arg 
                325                 330                 335     


Ser Ala Asp Ser Glu Asn Ala Leu Ser Val Gln Glu Arg Asn Val Pro 
            340                 345                 350         


Thr Lys Ser Pro Ser Ala Pro Ile Asn Trp Arg Arg Gly Lys Leu Leu 
        355                 360                 365             


Gly Gln Gly Ala Phe Gly Arg Val Tyr Leu Cys Tyr Asp Val Asp Thr 
    370                 375                 380                 


Gly Arg Glu Leu Ala Ser Lys Gln Val Gln Phe Asp Pro Asp Ser Pro 
385                 390                 395                 400 


Glu Thr Ser Lys Glu Val Ser Ala Leu Glu Cys Glu Ile Gln Leu Leu 
                405                 410                 415     


Lys Asn Leu Gln His Glu Arg Ile Val Gln Tyr Tyr Gly Cys Leu Arg 
            420                 425                 430         


Asp Arg Ala Glu Lys Thr Leu Thr Ile Phe Met Glu Tyr Met Pro Gly 
        435                 440                 445             


Gly Ser Val Lys Asp Gln Leu Lys Ala Tyr Gly Ala Leu Thr Glu Ser 
    450                 455                 460                 


Val Thr Arg Lys Tyr Thr Arg Gln Ile Leu Glu Gly Met Ser Tyr Leu 
465                 470                 475                 480 


His Ser Asn Met Ile Val His Arg Asp Ile Lys Gly Ala Asn Ile Leu 
                485                 490                 495     


Arg Asp Ser Ala Gly Asn Val Lys Leu Gly Asp Phe Gly Ala Ser Lys 
            500                 505                 510         


Arg Leu Gln Thr Ile Cys Met Ser Gly Thr Gly Met Arg Ser Val Thr 
        515                 520                 525             


Gly Thr Pro Tyr Trp Met Ser Pro Glu Val Ile Ser Gly Glu Gly Tyr 
    530                 535                 540                 


Gly Arg Lys Ala Asp Val Trp Ser Leu Gly Cys Thr Val Val Glu Met 
545                 550                 555                 560 


Leu Thr Glu Lys Pro Pro Trp Ala Glu Tyr Glu Ala Met Ala Ala Ile 
                565                 570                 575     


Phe Lys Ile Ala Thr Gln Pro Thr Asn Pro Gln Leu Pro Ser His Ile 
            580                 585                 590         


Ser Glu His Gly Arg Asp Phe Leu Arg Arg Ile Phe Val Glu Ala Arg 
        595                 600                 605             


Gln Arg Pro Ser Ala Glu Glu Leu Leu Thr His His Phe Ala Gln Leu 
    610                 615                 620                 


Met Tyr 
625     


<210>  1528
<211>  964
<212>  PRT
<213>  Homo sapiens

<400>  1528

Met Asp Glu Gln Ser Val Glu Ser Ile Ala Glu Val Phe Arg Cys Phe 
1               5                   10                  15      


Ile Cys Met Glu Lys Leu Arg Asp Ala Arg Leu Cys Pro His Cys Ser 
            20                  25                  30          


Lys Leu Cys Cys Phe Ser Cys Ile Arg Arg Trp Leu Thr Glu Gln Arg 
        35                  40                  45              


Ala Gln Cys Pro His Cys Arg Ala Pro Leu Gln Leu Arg Glu Leu Val 
    50                  55                  60                  


Asn Cys Arg Trp Ala Glu Glu Val Thr Gln Gln Leu Asp Thr Leu Gln 
65                  70                  75                  80  


Leu Cys Ser Leu Thr Lys His Glu Glu Asn Glu Lys Asp Lys Cys Glu 
                85                  90                  95      


Asn His His Glu Lys Leu Ser Val Phe Cys Trp Thr Cys Lys Lys Cys 
            100                 105                 110         


Ile Cys His Gln Cys Ala Leu Trp Gly Gly Met His Gly Gly His Thr 
        115                 120                 125             


Phe Lys Pro Leu Ala Glu Ile Tyr Glu Gln His Val Thr Lys Val Asn 
    130                 135                 140                 


Glu Glu Val Ala Lys Leu Arg Arg Arg Leu Met Glu Leu Ile Ser Leu 
145                 150                 155                 160 


Val Gln Glu Val Glu Arg Asn Val Glu Ala Val Arg Asn Ala Lys Asp 
                165                 170                 175     


Glu Arg Val Arg Glu Ile Arg Asn Ala Val Glu Met Met Ile Ala Arg 
            180                 185                 190         


Leu Asp Thr Gln Leu Lys Asn Lys Leu Ile Thr Leu Met Gly Gln Lys 
        195                 200                 205             


Thr Ser Leu Thr Gln Glu Thr Glu Leu Leu Glu Ser Leu Leu Gln Glu 
    210                 215                 220                 


Val Glu His Gln Leu Arg Ser Cys Ser Lys Ser Glu Leu Ile Ser Lys 
225                 230                 235                 240 


Ser Ser Glu Ile Leu Met Met Phe Gln Gln Val His Arg Lys Pro Met 
                245                 250                 255     


Ala Ser Phe Val Thr Thr Pro Val Pro Pro Asp Phe Thr Ser Glu Leu 
            260                 265                 270         


Val Pro Ser Tyr Asp Ser Ala Thr Phe Val Leu Glu Asn Phe Ser Thr 
        275                 280                 285             


Leu Arg Gln Arg Ala Asp Pro Val Tyr Ser Pro Pro Leu Gln Val Ser 
    290                 295                 300                 


Gly Leu Cys Trp Arg Leu Lys Val Tyr Pro Asp Gly Asn Gly Val Val 
305                 310                 315                 320 


Arg Gly Tyr Tyr Leu Ser Val Phe Leu Glu Leu Ser Ala Gly Leu Pro 
                325                 330                 335     


Glu Thr Ser Lys Tyr Glu Tyr Arg Val Glu Met Val His Gln Ser Cys 
            340                 345                 350         


Asn Asp Pro Thr Lys Asn Ile Ile Arg Glu Phe Ala Ser Asp Phe Glu 
        355                 360                 365             


Val Gly Glu Cys Trp Gly Tyr Asn Arg Phe Phe Arg Leu Asp Leu Leu 
    370                 375                 380                 


Ala Asn Glu Gly Tyr Leu Asn Pro Gln Asn Asp Thr Val Ile Leu Arg 
385                 390                 395                 400 


Phe Gln Val Arg Ser Pro Thr Phe Phe Gln Lys Ser Arg Asp Gln His 
                405                 410                 415     


Trp Tyr Ile Thr Gln Leu Glu Ala Ala Gln Thr Ser Tyr Ile Gln Gln 
            420                 425                 430         


Ile Asn Asn Leu Lys Glu Arg Leu Thr Ile Glu Leu Ser Arg Thr Gln 
        435                 440                 445             


Lys Ser Arg Asp Leu Ser Pro Pro Asp Asn His Leu Ser Pro Gln Asn 
    450                 455                 460                 


Asp Asp Ala Leu Glu Thr Arg Ala Lys Lys Ser Ala Cys Ser Asp Met 
465                 470                 475                 480 


Leu Leu Glu Gly Gly Pro Thr Thr Ala Ser Val Arg Glu Ala Lys Glu 
                485                 490                 495     


Asp Glu Glu Asp Glu Glu Lys Ile Gln Asn Glu Asp Tyr His His Glu 
            500                 505                 510         


Leu Ser Asp Gly Asp Leu Asp Leu Asp Leu Val Tyr Glu Asp Glu Val 
        515                 520                 525             


Asn Gln Leu Asp Gly Ser Ser Ser Ser Ala Ser Ser Thr Ala Thr Ser 
    530                 535                 540                 


Asn Thr Glu Glu Asn Asp Ile Asp Glu Glu Thr Met Ser Gly Glu Asn 
545                 550                 555                 560 


Asp Val Glu Tyr Asn Asn Met Glu Leu Glu Glu Gly Glu Leu Met Glu 
                565                 570                 575     


Asp Ala Ala Ala Ala Gly Pro Ala Gly Ser Ser His Gly Tyr Val Gly 
            580                 585                 590         


Ser Ser Ser Arg Ile Ser Arg Arg Thr His Leu Cys Ser Ala Ala Thr 
        595                 600                 605             


Ser Ser Leu Leu Asp Ile Asp Pro Leu Ile Leu Ile His Leu Leu Asp 
    610                 615                 620                 


Leu Lys Asp Arg Ser Ser Ile Glu Asn Leu Trp Gly Leu Gln Pro Arg 
625                 630                 635                 640 


Pro Pro Ala Ser Leu Leu Gln Pro Thr Ala Ser Tyr Ser Arg Lys Asp 
                645                 650                 655     


Lys Asp Gln Arg Lys Gln Gln Ala Met Trp Arg Val Pro Ser Asp Leu 
            660                 665                 670         


Lys Met Leu Lys Arg Leu Lys Thr Gln Met Ala Glu Val Arg Cys Met 
        675                 680                 685             


Lys Thr Asp Val Lys Asn Thr Leu Ser Glu Ile Lys Ser Ser Ser Ala 
    690                 695                 700                 


Ala Ser Gly Asp Met Gln Thr Ser Leu Phe Ser Ala Asp Gln Ala Ala 
705                 710                 715                 720 


Leu Ala Ala Cys Gly Thr Glu Asn Ser Gly Arg Leu Gln Asp Leu Gly 
                725                 730                 735     


Met Glu Leu Leu Ala Lys Ser Ser Val Ala Asn Cys Tyr Ile Arg Asn 
            740                 745                 750         


Ser Thr Asn Lys Lys Ser Asn Ser Pro Lys Pro Ala Arg Ser Ser Val 
        755                 760                 765             


Ala Gly Ser Leu Ser Leu Arg Arg Ala Val Asp Pro Gly Glu Asn Ser 
    770                 775                 780                 


Arg Ser Lys Gly Asp Cys Gln Thr Leu Ser Glu Gly Ser Pro Gly Ser 
785                 790                 795                 800 


Ser Gln Ser Gly Ser Arg His Ser Ser Pro Arg Ala Leu Ile His Gly 
                805                 810                 815     


Ser Ile Gly Asp Ile Leu Pro Lys Thr Glu Asp Arg Gln Cys Lys Ala 
            820                 825                 830         


Leu Asp Ser Asp Ala Val Val Val Ala Val Phe Ser Gly Leu Pro Ala 
        835                 840                 845             


Val Glu Lys Arg Arg Lys Met Val Thr Leu Gly Ala Asn Ala Lys Gly 
    850                 855                 860                 


Gly His Leu Glu Gly Leu Gln Met Thr Asp Leu Glu Asn Asn Ser Glu 
865                 870                 875                 880 


Thr Gly Glu Leu Gln Pro Val Leu Pro Glu Gly Ala Ser Ala Ala Pro 
                885                 890                 895     


Glu Glu Gly Met Ser Ser Asp Ser Asp Ile Glu Cys Asp Thr Glu Asn 
            900                 905                 910         


Glu Glu Gln Glu Glu His Thr Ser Val Gly Gly Phe His Asp Ser Phe 
        915                 920                 925             


Met Val Met Thr Gln Pro Pro Asp Glu Asp Thr His Ser Ser Phe Pro 
    930                 935                 940                 


Asp Gly Glu Gln Ile Gly Pro Glu Asp Leu Ser Phe Asn Thr Asp Glu 
945                 950                 955                 960 


Asn Ser Gly Arg 
                


<210>  1529
<211>  710
<212>  PRT
<213>  Homo sapiens

<400>  1529

Met Val Lys Leu Ala Lys Ala Gly Lys Asn Gln Gly Asp Pro Lys Lys 
1               5                   10                  15      


Met Ala Pro Pro Pro Lys Glu Val Glu Glu Asp Ser Glu Asp Glu Glu 
            20                  25                  30          


Met Ser Glu Asp Glu Glu Asp Asp Ser Ser Gly Glu Glu Val Val Ile 
        35                  40                  45              


Pro Gln Lys Lys Gly Lys Lys Ala Ala Ala Thr Ser Ala Lys Lys Val 
    50                  55                  60                  


Val Val Ser Pro Thr Lys Lys Val Ala Val Ala Thr Pro Ala Lys Lys 
65                  70                  75                  80  


Ala Ala Val Thr Pro Gly Lys Lys Ala Ala Ala Thr Pro Ala Lys Lys 
                85                  90                  95      


Thr Val Thr Pro Ala Lys Ala Val Thr Thr Pro Gly Lys Lys Gly Ala 
            100                 105                 110         


Thr Pro Gly Lys Ala Leu Val Ala Thr Pro Gly Lys Lys Gly Ala Ala 
        115                 120                 125             


Ile Pro Ala Lys Gly Ala Lys Asn Gly Lys Asn Ala Lys Lys Glu Asp 
    130                 135                 140                 


Ser Asp Glu Glu Glu Asp Asp Asp Ser Glu Glu Asp Glu Glu Asp Asp 
145                 150                 155                 160 


Glu Asp Glu Asp Glu Asp Glu Asp Glu Ile Glu Pro Ala Ala Met Lys 
                165                 170                 175     


Ala Ala Ala Ala Ala Pro Ala Ser Glu Asp Glu Asp Asp Glu Asp Asp 
            180                 185                 190         


Glu Asp Asp Glu Asp Asp Asp Asp Asp Glu Glu Asp Asp Ser Glu Glu 
        195                 200                 205             


Glu Ala Met Glu Thr Thr Pro Ala Lys Gly Lys Lys Ala Ala Lys Val 
    210                 215                 220                 


Val Pro Val Lys Ala Lys Asn Val Ala Glu Asp Glu Asp Glu Glu Glu 
225                 230                 235                 240 


Asp Asp Glu Asp Glu Asp Asp Asp Asp Asp Glu Asp Asp Glu Asp Asp 
                245                 250                 255     


Asp Asp Glu Asp Asp Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Pro 
            260                 265                 270         


Val Lys Glu Ala Pro Gly Lys Arg Lys Lys Glu Met Ala Lys Gln Lys 
        275                 280                 285             


Ala Ala Pro Glu Ala Lys Lys Gln Lys Val Glu Gly Thr Glu Pro Thr 
    290                 295                 300                 


Thr Ala Phe Asn Leu Phe Val Gly Asn Leu Asn Phe Asn Lys Ser Ala 
305                 310                 315                 320 


Pro Glu Leu Lys Thr Gly Ile Ser Asp Val Phe Ala Lys Asn Asp Leu 
                325                 330                 335     


Ala Val Val Asp Val Arg Ile Gly Met Thr Arg Lys Phe Gly Tyr Val 
            340                 345                 350         


Asp Phe Glu Ser Ala Glu Asp Leu Glu Lys Ala Leu Glu Leu Thr Gly 
        355                 360                 365             


Leu Lys Val Phe Gly Asn Glu Ile Lys Leu Glu Lys Pro Lys Gly Lys 
    370                 375                 380                 


Asp Ser Lys Lys Glu Arg Asp Ala Arg Thr Leu Leu Ala Lys Asn Leu 
385                 390                 395                 400 


Pro Tyr Lys Val Thr Gln Asp Glu Leu Lys Glu Val Phe Glu Asp Ala 
                405                 410                 415     


Ala Glu Ile Arg Leu Val Ser Lys Asp Gly Lys Ser Lys Gly Ile Ala 
            420                 425                 430         


Tyr Ile Glu Phe Lys Thr Glu Ala Asp Ala Glu Lys Thr Phe Glu Glu 
        435                 440                 445             


Lys Gln Gly Thr Glu Ile Asp Gly Arg Ser Ile Ser Leu Tyr Tyr Thr 
    450                 455                 460                 


Gly Glu Lys Gly Gln Asn Gln Asp Tyr Arg Gly Gly Lys Asn Ser Thr 
465                 470                 475                 480 


Trp Ser Gly Glu Ser Lys Thr Leu Val Leu Ser Asn Leu Ser Tyr Ser 
                485                 490                 495     


Ala Thr Glu Glu Thr Leu Gln Glu Val Phe Glu Lys Ala Thr Phe Ile 
            500                 505                 510         


Lys Val Pro Gln Asn Gln Asn Gly Lys Ser Lys Gly Tyr Ala Phe Ile 
        515                 520                 525             


Glu Phe Ala Ser Phe Glu Asp Ala Lys Glu Ala Leu Asn Ser Cys Asn 
    530                 535                 540                 


Lys Arg Glu Ile Glu Gly Arg Ala Ile Arg Leu Glu Leu Gln Gly Pro 
545                 550                 555                 560 


Arg Gly Ser Pro Asn Ala Arg Ser Gln Pro Ser Lys Thr Leu Phe Val 
                565                 570                 575     


Lys Gly Leu Ser Glu Asp Thr Thr Glu Glu Thr Leu Lys Glu Ser Phe 
            580                 585                 590         


Asp Gly Ser Val Arg Ala Arg Ile Val Thr Asp Arg Glu Thr Gly Ser 
        595                 600                 605             


Ser Lys Gly Phe Gly Phe Val Asp Phe Asn Ser Glu Glu Asp Ala Lys 
    610                 615                 620                 


Ala Ala Lys Glu Ala Met Glu Asp Gly Glu Ile Asp Gly Asn Lys Val 
625                 630                 635                 640 


Thr Leu Asp Trp Ala Lys Pro Lys Gly Glu Gly Gly Phe Gly Gly Arg 
                645                 650                 655     


Gly Gly Gly Arg Gly Gly Phe Gly Gly Arg Gly Gly Gly Arg Gly Gly 
            660                 665                 670         


Arg Gly Gly Phe Gly Gly Arg Gly Arg Gly Gly Phe Gly Gly Arg Gly 
        675                 680                 685             


Gly Phe Arg Gly Gly Arg Gly Gly Gly Gly Asp His Lys Pro Gln Gly 
    690                 695                 700                 


Lys Lys Thr Lys Phe Glu 
705                 710 


<210>  1530
<211>  1151
<212>  PRT
<213>  Homo sapiens

<400>  1530

Met Leu Arg Arg Val Thr Val Ala Ala Val Cys Ala Thr Arg Arg Lys 
1               5                   10                  15      


Leu Cys Glu Ala Gly Arg Glu Leu Ala Ala Leu Trp Gly Ile Glu Thr 
            20                  25                  30          


Arg Gly Arg Cys Glu Asp Ser Ala Ala Ala Arg Pro Phe Pro Ile Leu 
        35                  40                  45              


Ala Met Pro Gly Arg Asn Lys Ala Lys Ser Thr Cys Ser Cys Pro Asp 
    50                  55                  60                  


Leu Gln Pro Asn Gly Gln Asp Leu Gly Glu Asn Ser Arg Val Ala Arg 
65                  70                  75                  80  


Leu Gly Ala Asp Glu Ser Glu Glu Glu Gly Arg Arg Gly Ser Leu Ser 
                85                  90                  95      


Asn Ala Gly Asp Pro Glu Ile Val Lys Ser Pro Ser Asp Pro Lys Gln 
            100                 105                 110         


Tyr Arg Tyr Ile Lys Leu Gln Asn Gly Leu Gln Ala Leu Leu Ile Ser 
        115                 120                 125             


Asp Leu Ser Asn Met Glu Gly Lys Thr Gly Asn Thr Thr Asp Asp Glu 
    130                 135                 140                 


Glu Glu Glu Glu Val Glu Glu Glu Glu Glu Asp Asp Asp Glu Asp Ser 
145                 150                 155                 160 


Gly Ala Glu Ile Glu Asp Asp Asp Glu Glu Gly Phe Asp Asp Glu Asp 
                165                 170                 175     


Glu Phe Asp Asp Glu His Asp Asp Asp Leu Asp Thr Glu Asp Asn Glu 
            180                 185                 190         


Leu Glu Glu Leu Glu Glu Arg Ala Glu Ala Arg Lys Lys Thr Thr Glu 
        195                 200                 205             


Lys Gln Ser Ala Ala Ala Leu Cys Val Gly Val Gly Ser Phe Ala Asp 
    210                 215                 220                 


Pro Asp Asp Leu Pro Gly Leu Ala His Phe Leu Glu His Met Val Phe 
225                 230                 235                 240 


Met Gly Ser Leu Lys Tyr Pro Asp Glu Asn Gly Phe Asp Ala Phe Leu 
                245                 250                 255     


Lys Lys His Gly Gly Ser Asp Asn Ala Ser Thr Asp Cys Glu Arg Thr 
            260                 265                 270         


Val Phe Gln Phe Asp Val Gln Arg Lys Tyr Phe Lys Glu Ala Leu Asp 
        275                 280                 285             


Arg Trp Ala Gln Phe Phe Ile His Pro Leu Met Ile Arg Asp Ala Ile 
    290                 295                 300                 


Asp Arg Glu Val Glu Ala Val Asp Ser Glu Tyr Gln Leu Ala Arg Pro 
305                 310                 315                 320 


Ser Asp Ala Asn Arg Lys Glu Met Leu Phe Gly Ser Leu Ala Arg Pro 
                325                 330                 335     


Gly His Pro Met Gly Lys Phe Phe Trp Gly Asn Ala Glu Thr Leu Lys 
            340                 345                 350         


His Glu Pro Arg Lys Asn Asn Ile Asp Thr His Ala Arg Leu Arg Glu 
        355                 360                 365             


Phe Trp Met Arg Tyr Tyr Ser Ser His Tyr Met Thr Leu Val Val Gln 
    370                 375                 380                 


Ser Lys Glu Thr Leu Asp Thr Leu Glu Lys Trp Val Thr Glu Ile Phe 
385                 390                 395                 400 


Ser Gln Ile Pro Asn Asn Gly Leu Pro Arg Pro Asn Phe Gly His Leu 
                405                 410                 415     


Thr Asp Pro Phe Asp Thr Pro Ala Phe Asn Lys Leu Tyr Arg Val Val 
            420                 425                 430         


Pro Ile Arg Lys Ile His Ala Leu Thr Ile Thr Trp Ala Leu Pro Pro 
        435                 440                 445             


Gln Gln Gln His Tyr Arg Val Lys Pro Leu His Tyr Ile Ser Trp Leu 
    450                 455                 460                 


Val Gly His Glu Gly Lys Gly Ser Ile Leu Ser Phe Leu Arg Lys Lys 
465                 470                 475                 480 


Cys Trp Ala Leu Ala Leu Phe Gly Gly Asn Gly Glu Thr Gly Phe Glu 
                485                 490                 495     


Gln Asn Ser Thr Tyr Ser Val Phe Ser Ile Ser Ile Thr Leu Thr Asp 
            500                 505                 510         


Glu Gly Tyr Glu His Phe Tyr Glu Val Ala Tyr Thr Val Phe Gln Tyr 
        515                 520                 525             


Leu Lys Met Leu Gln Lys Leu Gly Pro Glu Lys Arg Ile Phe Glu Glu 
    530                 535                 540                 


Ile Arg Lys Ile Glu Asp Asn Glu Phe His Tyr Gln Glu Gln Thr Asp 
545                 550                 555                 560 


Pro Val Glu Tyr Val Glu Asn Met Cys Glu Asn Met Gln Leu Tyr Pro 
                565                 570                 575     


Leu Gln Asp Ile Leu Thr Gly Asp Gln Leu Leu Phe Glu Tyr Lys Pro 
            580                 585                 590         


Glu Val Ile Gly Glu Ala Leu Asn Gln Leu Val Pro Gln Lys Ala Asn 
        595                 600                 605             


Leu Val Leu Leu Ser Gly Ala Asn Glu Gly Lys Cys Asp Leu Lys Glu 
    610                 615                 620                 


Lys Trp Phe Gly Thr Gln Tyr Ser Ile Glu Asp Ile Glu Asn Ser Trp 
625                 630                 635                 640 


Ala Glu Leu Trp Asn Ser Asn Phe Glu Leu Asn Pro Asp Leu His Leu 
                645                 650                 655     


Pro Ala Glu Asn Lys Tyr Ile Ala Thr Asp Phe Thr Leu Lys Ala Phe 
            660                 665                 670         


Asp Cys Pro Glu Thr Glu Tyr Pro Val Lys Ile Val Asn Thr Pro Gln 
        675                 680                 685             


Gly Cys Leu Trp Tyr Lys Lys Asp Asn Lys Phe Lys Ile Pro Lys Ala 
    690                 695                 700                 


Tyr Ile Arg Phe His Leu Ile Ser Pro Leu Ile Gln Lys Ser Ala Ala 
705                 710                 715                 720 


Asn Val Val Leu Phe Asp Ile Phe Val Asn Ile Leu Thr His Asn Leu 
                725                 730                 735     


Ala Glu Pro Ala Tyr Glu Ala Asp Val Ala Gln Leu Glu Tyr Lys Leu 
            740                 745                 750         


Val Ala Gly Glu His Gly Leu Ile Ile Arg Val Lys Gly Phe Asn His 
        755                 760                 765             


Lys Leu Pro Leu Leu Phe Gln Leu Ile Ile Asp Tyr Leu Ala Glu Phe 
    770                 775                 780                 


Asn Ser Thr Pro Ala Val Phe Thr Met Ile Thr Glu Gln Leu Lys Lys 
785                 790                 795                 800 


Thr Tyr Phe Asn Ile Leu Ile Lys Pro Glu Thr Leu Ala Lys Asp Val 
                805                 810                 815     


Arg Leu Leu Ile Leu Glu Tyr Ala Arg Trp Ser Met Ile Asp Lys Tyr 
            820                 825                 830         


Gln Ala Leu Met Asp Gly Leu Ser Leu Glu Ser Leu Leu Ser Phe Val 
        835                 840                 845             


Lys Glu Phe Lys Ser Gln Leu Phe Val Glu Gly Leu Val Gln Gly Asn 
    850                 855                 860                 


Val Thr Ser Thr Glu Ser Met Asp Phe Leu Lys Tyr Val Val Asp Lys 
865                 870                 875                 880 


Leu Asn Phe Lys Pro Leu Glu Gln Glu Met Pro Val Gln Phe Gln Val 
                885                 890                 895     


Val Glu Leu Pro Ser Gly His His Leu Cys Lys Val Lys Ala Leu Asn 
            900                 905                 910         


Lys Gly Asp Ala Asn Ser Glu Val Thr Val Tyr Tyr Gln Ser Gly Thr 
        915                 920                 925             


Arg Ser Leu Arg Glu Tyr Thr Leu Met Glu Leu Leu Val Met His Met 
    930                 935                 940                 


Glu Glu Pro Cys Phe Asp Phe Leu Arg Thr Lys Gln Thr Leu Gly Tyr 
945                 950                 955                 960 


His Val Tyr Pro Thr Cys Arg Asn Thr Ser Gly Ile Leu Gly Phe Ser 
                965                 970                 975     


Val Thr Val Gly Thr Gln Ala Thr Lys Tyr Asn Ser Glu Val Val Asp 
            980                 985                 990         


Lys Lys Ile Glu Glu Phe Leu Ser  Ser Phe Glu Glu Lys  Ile Glu Asn 
        995                 1000                 1005             


Leu Thr  Glu Glu Ala Phe Asn  Thr Gln Val Thr Ala  Leu Ile Lys 
    1010                 1015                 1020             


Leu Lys  Glu Cys Glu Asp Thr  His Leu Gly Glu Glu  Val Asp Arg 
    1025                 1030                 1035             


Asn Trp  Asn Glu Val Val Thr  Gln Gln Tyr Leu Phe  Asp Arg Leu 
    1040                 1045                 1050             


Ala His  Glu Ile Glu Ala Leu  Lys Ser Phe Ser Lys  Ser Asp Leu 
    1055                 1060                 1065             


Val Asn  Trp Phe Lys Ala His  Arg Gly Pro Gly Ser  Lys Met Leu 
    1070                 1075                 1080             


Ser Val  His Val Val Gly Tyr  Gly Lys Tyr Glu Leu  Glu Glu Asp 
    1085                 1090                 1095             


Gly Thr  Pro Ser Ser Glu Asp  Ser Asn Ser Ser Cys  Glu Val Met 
    1100                 1105                 1110             


Gln Leu  Thr Tyr Leu Pro Thr  Ser Pro Leu Leu Ala  Asp Cys Ile 
    1115                 1120                 1125             


Ile Pro  Ile Thr Asp Ile Arg  Ala Phe Thr Thr Thr  Leu Asn Leu 
    1130                 1135                 1140             


Leu Pro  Tyr His Lys Ile Val  Lys 
    1145                 1150     


<210>  1531
<211>  324
<212>  PRT
<213>  Homo sapiens

<400>  1531

Met Ser Ser Glu Ala Glu Thr Gln Gln Pro Pro Ala Ala Pro Pro Ala 
1               5                   10                  15      


Ala Pro Ala Leu Ser Ala Ala Asp Thr Lys Pro Gly Thr Thr Gly Ser 
            20                  25                  30          


Gly Ala Gly Ser Gly Gly Pro Gly Gly Leu Thr Ser Ala Ala Pro Ala 
        35                  40                  45              


Gly Gly Asp Lys Lys Val Ile Ala Thr Lys Val Leu Gly Thr Val Lys 
    50                  55                  60                  


Trp Phe Asn Val Arg Asn Gly Tyr Gly Phe Ile Asn Arg Asn Asp Thr 
65                  70                  75                  80  


Lys Glu Asp Val Phe Val His Gln Thr Ala Ile Lys Lys Asn Asn Pro 
                85                  90                  95      


Arg Lys Tyr Leu Arg Ser Val Gly Asp Gly Glu Thr Val Glu Phe Asp 
            100                 105                 110         


Val Val Glu Gly Glu Lys Gly Ala Glu Ala Ala Asn Val Thr Gly Pro 
        115                 120                 125             


Gly Gly Val Pro Val Gln Gly Ser Lys Tyr Ala Ala Asp Arg Asn His 
    130                 135                 140                 


Tyr Arg Arg Tyr Pro Arg Arg Arg Gly Pro Pro Arg Asn Tyr Gln Gln 
145                 150                 155                 160 


Asn Tyr Gln Asn Ser Glu Ser Gly Glu Lys Asn Glu Gly Ser Glu Ser 
                165                 170                 175     


Ala Pro Glu Gly Gln Ala Gln Gln Arg Arg Pro Tyr Arg Arg Arg Arg 
            180                 185                 190         


Phe Pro Pro Tyr Tyr Met Arg Arg Pro Tyr Gly Arg Arg Pro Gln Tyr 
        195                 200                 205             


Ser Asn Pro Pro Val Gln Gly Glu Val Met Glu Gly Ala Asp Asn Gln 
    210                 215                 220                 


Gly Ala Gly Glu Gln Gly Arg Pro Val Arg Gln Asn Met Tyr Arg Gly 
225                 230                 235                 240 


Tyr Arg Pro Arg Phe Arg Arg Gly Pro Pro Arg Gln Arg Gln Pro Arg 
                245                 250                 255     


Glu Asp Gly Asn Glu Glu Asp Lys Glu Asn Gln Gly Asp Glu Thr Gln 
            260                 265                 270         


Gly Gln Gln Pro Pro Gln Arg Arg Tyr Arg Arg Asn Phe Asn Tyr Arg 
        275                 280                 285             


Arg Arg Arg Pro Glu Asn Pro Lys Pro Gln Asp Gly Lys Glu Thr Lys 
    290                 295                 300                 


Ala Ala Asp Pro Pro Ala Glu Asn Ser Ser Ala Pro Glu Ala Glu Gln 
305                 310                 315                 320 


Gly Gly Ala Glu 
                


<210>  1532
<211>  187
<212>  PRT
<213>  Homo sapiens

<400>  1532

Met Pro Val Asp Leu Ser Lys Trp Ser Gly Pro Leu Ser Leu Gln Glu 
1               5                   10                  15      


Val Asp Glu Gln Pro Gln His Pro Leu His Val Thr Tyr Ala Gly Ala 
            20                  25                  30          


Ala Val Asp Glu Leu Gly Lys Val Leu Thr Pro Thr Gln Val Lys Asn 
        35                  40                  45              


Arg Pro Thr Ser Ile Ser Trp Asp Gly Leu Asp Ser Gly Lys Leu Tyr 
    50                  55                  60                  


Thr Leu Val Leu Thr Asp Pro Asp Ala Pro Ser Arg Lys Asp Pro Lys 
65                  70                  75                  80  


Tyr Arg Glu Trp His His Phe Leu Val Val Asn Met Lys Gly Asn Asp 
                85                  90                  95      


Ile Ser Ser Gly Thr Val Leu Ser Asp Tyr Val Gly Ser Gly Pro Pro 
            100                 105                 110         


Lys Gly Thr Gly Leu His Arg Tyr Val Trp Leu Val Tyr Glu Gln Asp 
        115                 120                 125             


Arg Pro Leu Lys Cys Asp Glu Pro Ile Leu Ser Asn Arg Ser Gly Asp 
    130                 135                 140                 


His Arg Gly Lys Phe Lys Val Ala Ser Phe Arg Lys Lys Tyr Glu Leu 
145                 150                 155                 160 


Arg Ala Pro Val Ala Gly Thr Cys Tyr Gln Ala Glu Trp Asp Asp Tyr 
                165                 170                 175     


Val Pro Lys Leu Tyr Glu Gln Leu Ser Gly Lys 
            180                 185         


<210>  1533
<211>  531
<212>  PRT
<213>  Homo sapiens

<400>  1533

Met Ser Lys Pro His Ser Glu Ala Gly Thr Ala Phe Ile Gln Thr Gln 
1               5                   10                  15      


Gln Leu His Ala Ala Met Ala Asp Thr Phe Leu Glu His Met Cys Arg 
            20                  25                  30          


Leu Asp Ile Asp Ser Pro Pro Ile Thr Ala Arg Asn Thr Gly Ile Ile 
        35                  40                  45              


Cys Thr Ile Gly Pro Ala Ser Arg Ser Val Glu Thr Leu Lys Glu Met 
    50                  55                  60                  


Ile Lys Ser Gly Met Asn Val Ala Arg Leu Asn Phe Ser His Gly Thr 
65                  70                  75                  80  


His Glu Tyr His Ala Glu Thr Ile Lys Asn Val Arg Thr Ala Thr Glu 
                85                  90                  95      


Ser Phe Ala Ser Asp Pro Ile Leu Tyr Arg Pro Val Ala Val Ala Leu 
            100                 105                 110         


Asp Thr Lys Gly Pro Glu Ile Arg Thr Gly Leu Ile Lys Gly Ser Gly 
        115                 120                 125             


Thr Ala Glu Val Glu Leu Lys Lys Gly Ala Thr Leu Lys Ile Thr Leu 
    130                 135                 140                 


Asp Asn Ala Tyr Met Glu Lys Cys Asp Glu Asn Ile Leu Trp Leu Asp 
145                 150                 155                 160 


Tyr Lys Asn Ile Cys Lys Val Val Glu Val Gly Ser Lys Ile Tyr Val 
                165                 170                 175     


Asp Asp Gly Leu Ile Ser Leu Gln Val Lys Gln Lys Gly Ala Asp Phe 
            180                 185                 190         


Leu Val Thr Glu Val Glu Asn Gly Gly Ser Leu Gly Ser Lys Lys Gly 
        195                 200                 205             


Val Asn Leu Pro Gly Ala Ala Val Asp Leu Pro Ala Val Ser Glu Lys 
    210                 215                 220                 


Asp Ile Gln Asp Leu Lys Phe Gly Val Glu Gln Asp Val Asp Met Val 
225                 230                 235                 240 


Phe Ala Ser Phe Ile Arg Lys Ala Ser Asp Val His Glu Val Arg Lys 
                245                 250                 255     


Val Leu Gly Glu Lys Gly Lys Asn Ile Lys Ile Ile Ser Lys Ile Glu 
            260                 265                 270         


Asn His Glu Gly Val Arg Arg Phe Asp Glu Ile Leu Glu Ala Ser Asp 
        275                 280                 285             


Gly Ile Met Val Ala Arg Gly Asp Leu Gly Ile Glu Ile Pro Ala Glu 
    290                 295                 300                 


Lys Val Phe Leu Ala Gln Lys Met Met Ile Gly Arg Cys Asn Arg Ala 
305                 310                 315                 320 


Gly Lys Pro Val Ile Cys Ala Thr Gln Met Leu Glu Ser Met Ile Lys 
                325                 330                 335     


Lys Pro Arg Pro Thr Arg Ala Glu Gly Ser Asp Val Ala Asn Ala Val 
            340                 345                 350         


Leu Asp Gly Ala Asp Cys Ile Met Leu Ser Gly Glu Thr Ala Lys Gly 
        355                 360                 365             


Asp Tyr Pro Leu Glu Ala Val Arg Met Gln His Leu Ile Ala Arg Glu 
    370                 375                 380                 


Ala Glu Ala Ala Ile Tyr His Leu Gln Leu Phe Glu Glu Leu Arg Arg 
385                 390                 395                 400 


Leu Ala Pro Ile Thr Ser Asp Pro Thr Glu Ala Thr Ala Val Gly Ala 
                405                 410                 415     


Val Glu Ala Ser Phe Lys Cys Cys Ser Gly Ala Ile Ile Val Leu Thr 
            420                 425                 430         


Lys Ser Gly Arg Ser Ala His Gln Val Ala Arg Tyr Arg Pro Arg Ala 
        435                 440                 445             


Pro Ile Ile Ala Val Thr Arg Asn Pro Gln Thr Ala Arg Gln Ala His 
    450                 455                 460                 


Leu Tyr Arg Gly Ile Phe Pro Val Leu Cys Lys Asp Pro Val Gln Glu 
465                 470                 475                 480 


Ala Trp Ala Glu Asp Val Asp Leu Arg Val Asn Phe Ala Met Asn Val 
                485                 490                 495     


Gly Lys Ala Arg Gly Phe Phe Lys Lys Gly Asp Val Val Ile Val Leu 
            500                 505                 510         


Thr Gly Trp Arg Pro Gly Ser Gly Phe Thr Asn Thr Met Arg Val Val 
        515                 520                 525             


Pro Val Pro 
    530     


<210>  1534
<211>  370
<212>  PRT
<213>  Homo sapiens

<400>  1534

Met Ser His Pro Ser Pro Gln Ala Lys Pro Ser Asn Pro Ser Asn Pro 
1               5                   10                  15      


Arg Val Phe Phe Asp Val Asp Ile Gly Gly Glu Arg Val Gly Arg Ile 
            20                  25                  30          


Val Leu Glu Leu Phe Ala Asp Ile Val Pro Lys Thr Ala Glu Asn Phe 
        35                  40                  45              


Arg Ala Leu Cys Thr Gly Glu Lys Gly Ile Gly His Thr Thr Gly Lys 
    50                  55                  60                  


Pro Leu His Phe Lys Gly Cys Pro Phe His Arg Ile Ile Lys Lys Phe 
65                  70                  75                  80  


Met Ile Gln Gly Gly Asp Phe Ser Asn Gln Asn Gly Thr Gly Gly Glu 
                85                  90                  95      


Ser Ile Tyr Gly Glu Lys Phe Glu Asp Glu Asn Phe His Tyr Lys His 
            100                 105                 110         


Asp Arg Glu Gly Leu Leu Ser Met Ala Asn Ala Gly Arg Asn Thr Asn 
        115                 120                 125             


Gly Ser Gln Phe Phe Ile Thr Thr Val Pro Thr Pro His Leu Asp Gly 
    130                 135                 140                 


Lys His Val Val Phe Gly Gln Val Ile Lys Gly Ile Gly Val Ala Arg 
145                 150                 155                 160 


Ile Leu Glu Asn Val Glu Val Lys Gly Glu Lys Pro Ala Lys Leu Cys 
                165                 170                 175     


Val Ile Ala Glu Cys Gly Glu Leu Lys Glu Gly Asp Asp Gly Gly Ile 
            180                 185                 190         


Phe Pro Lys Asp Gly Ser Gly Asp Ser His Pro Asp Phe Pro Glu Asp 
        195                 200                 205             


Ala Asp Ile Asp Leu Lys Asp Val Asp Lys Ile Leu Leu Ile Thr Glu 
    210                 215                 220                 


Asp Leu Lys Asn Ile Gly Asn Thr Phe Phe Lys Ser Gln Asn Trp Glu 
225                 230                 235                 240 


Met Ala Ile Lys Lys Tyr Ala Glu Val Leu Arg Tyr Val Asp Ser Ser 
                245                 250                 255     


Lys Ala Val Ile Glu Thr Ala Asp Arg Ala Lys Leu Gln Pro Ile Ala 
            260                 265                 270         


Leu Ser Cys Val Leu Asn Ile Gly Ala Cys Lys Leu Lys Met Ser Asn 
        275                 280                 285             


Trp Gln Gly Ala Ile Asp Ser Cys Leu Glu Ala Leu Glu Leu Asp Pro 
    290                 295                 300                 


Ser Asn Thr Lys Ala Leu Tyr Arg Arg Ala Gln Gly Trp Gln Gly Leu 
305                 310                 315                 320 


Lys Glu Tyr Asp Gln Ala Leu Ala Asp Leu Lys Lys Ala Gln Gly Ile 
                325                 330                 335     


Ala Pro Glu Asp Lys Ala Ile Gln Ala Glu Leu Leu Lys Val Lys Gln 
            340                 345                 350         


Lys Ile Lys Ala Gln Lys Asp Lys Glu Lys Ala Val Tyr Ala Lys Met 
        355                 360                 365             


Phe Ala 
    370 


<210>  1535
<211>  255
<212>  PRT
<213>  Homo sapiens

<400>  1535

Met Ser Ser Ile Gly Thr Gly Tyr Asp Leu Ser Ala Ser Thr Phe Ser 
1               5                   10                  15      


Pro Asp Gly Arg Val Phe Gln Val Glu Tyr Ala Met Lys Ala Val Glu 
            20                  25                  30          


Asn Ser Ser Thr Ala Ile Gly Ile Arg Cys Lys Asp Gly Val Val Phe 
        35                  40                  45              


Gly Val Glu Lys Leu Val Leu Ser Lys Leu Tyr Glu Glu Gly Ser Asn 
    50                  55                  60                  


Lys Arg Leu Phe Asn Val Asp Arg His Val Gly Met Ala Val Ala Gly 
65                  70                  75                  80  


Leu Leu Ala Asp Ala Arg Ser Leu Ala Asp Ile Ala Arg Glu Glu Ala 
                85                  90                  95      


Ser Asn Phe Arg Ser Asn Phe Gly Tyr Asn Ile Pro Leu Lys His Leu 
            100                 105                 110         


Ala Asp Arg Val Ala Met Tyr Val His Ala Tyr Thr Leu Tyr Ser Ala 
        115                 120                 125             


Val Arg Pro Phe Gly Cys Ser Phe Met Leu Gly Ser Tyr Ser Val Asn 
    130                 135                 140                 


Asp Gly Ala Gln Leu Tyr Met Ile Asp Pro Ser Gly Val Ser Tyr Gly 
145                 150                 155                 160 


Tyr Trp Gly Cys Ala Ile Gly Lys Ala Arg Gln Ala Ala Lys Thr Glu 
                165                 170                 175     


Ile Glu Lys Leu Gln Met Lys Glu Met Thr Cys Arg Asp Ile Val Lys 
            180                 185                 190         


Glu Val Ala Lys Ile Ile Tyr Ile Val His Asp Glu Val Lys Asp Lys 
        195                 200                 205             


Ala Phe Glu Leu Glu Leu Ser Trp Val Gly Glu Leu Thr Asn Gly Arg 
    210                 215                 220                 


His Glu Ile Val Pro Lys Asp Ile Arg Glu Glu Ala Glu Lys Tyr Ala 
225                 230                 235                 240 


Lys Glu Ser Leu Lys Glu Glu Asp Glu Ser Asp Asp Asp Asn Met 
                245                 250                 255 


<210>  1536
<211>  288
<212>  PRT
<213>  Homo sapiens

<400>  1536

Met Ala Gly Glu Lys Val Glu Lys Pro Asp Thr Lys Glu Lys Lys Pro 
1               5                   10                  15      


Glu Ala Lys Lys Val Asp Ala Gly Gly Lys Val Lys Lys Gly Asn Leu 
            20                  25                  30          


Lys Ala Lys Lys Pro Lys Lys Gly Lys Pro His Cys Ser Arg Asn Pro 
        35                  40                  45              


Val Leu Val Arg Gly Ile Gly Arg Tyr Ser Arg Ser Ala Met Tyr Ser 
    50                  55                  60                  


Arg Lys Ala Met Tyr Lys Arg Lys Tyr Ser Ala Ala Lys Ser Lys Val 
65                  70                  75                  80  


Glu Lys Lys Lys Lys Glu Lys Val Leu Ala Thr Val Thr Lys Pro Val 
                85                  90                  95      


Gly Gly Asp Lys Asn Gly Gly Thr Arg Val Val Lys Leu Arg Lys Met 
            100                 105                 110         


Pro Arg Tyr Tyr Pro Thr Glu Asp Val Pro Arg Lys Leu Leu Ser His 
        115                 120                 125             


Gly Lys Lys Pro Phe Ser Gln His Val Arg Lys Leu Arg Ala Ser Ile 
    130                 135                 140                 


Thr Pro Gly Thr Ile Leu Ile Ile Leu Thr Gly Arg His Arg Gly Lys 
145                 150                 155                 160 


Arg Val Val Phe Leu Lys Gln Leu Ala Ser Gly Leu Leu Leu Val Thr 
                165                 170                 175     


Gly Pro Leu Val Leu Asn Arg Val Pro Leu Arg Arg Thr His Gln Lys 
            180                 185                 190         


Phe Val Ile Ala Thr Ser Thr Lys Ile Asp Ile Ser Asn Val Lys Ile 
        195                 200                 205             


Pro Lys His Leu Thr Asp Ala Tyr Phe Lys Lys Lys Lys Leu Arg Lys 
    210                 215                 220                 


Pro Arg His Gln Glu Gly Glu Ile Phe Asp Thr Glu Lys Glu Lys Tyr 
225                 230                 235                 240 


Glu Ile Thr Glu Gln Arg Lys Ile Asp Gln Lys Ala Val Asp Ser Gln 
                245                 250                 255     


Ile Leu Pro Lys Ile Lys Ala Ile Pro Gln Leu Gln Gly Tyr Leu Arg 
            260                 265                 270         


Ser Val Phe Ala Leu Thr Asn Gly Ile Tyr Pro His Lys Leu Val Phe 
        275                 280                 285             


<210>  1537
<211>  248
<212>  PRT
<213>  Homo sapiens

<400>  1537

Met Glu Gly Val Glu Glu Lys Lys Lys Glu Val Pro Ala Val Pro Glu 
1               5                   10                  15      


Thr Leu Lys Lys Lys Arg Arg Asn Phe Ala Glu Leu Lys Ile Lys Arg 
            20                  25                  30          


Leu Arg Lys Lys Phe Ala Gln Lys Met Leu Arg Lys Ala Arg Arg Lys 
        35                  40                  45              


Leu Ile Tyr Glu Lys Ala Lys His Tyr His Lys Glu Tyr Arg Gln Met 
    50                  55                  60                  


Tyr Arg Thr Glu Ile Arg Met Ala Arg Met Ala Arg Lys Ala Gly Asn 
65                  70                  75                  80  


Phe Tyr Val Pro Ala Glu Pro Lys Leu Ala Phe Val Ile Arg Ile Arg 
                85                  90                  95      


Gly Ile Asn Gly Val Ser Pro Lys Val Arg Lys Val Leu Gln Leu Leu 
            100                 105                 110         


Arg Leu Arg Gln Ile Phe Asn Gly Thr Phe Val Lys Leu Asn Lys Ala 
        115                 120                 125             


Ser Ile Asn Met Leu Arg Ile Val Glu Pro Tyr Ile Ala Trp Gly Tyr 
    130                 135                 140                 


Pro Asn Leu Lys Ser Val Asn Glu Leu Ile Tyr Lys Arg Gly Tyr Gly 
145                 150                 155                 160 


Lys Ile Asn Lys Lys Arg Ile Ala Leu Thr Asp Asn Ala Leu Ile Ala 
                165                 170                 175     


Arg Ser Leu Gly Lys Tyr Gly Ile Ile Cys Met Glu Asp Leu Ile His 
            180                 185                 190         


Glu Ile Tyr Thr Val Gly Lys Arg Phe Lys Glu Ala Asn Asn Phe Leu 
        195                 200                 205             


Trp Pro Phe Lys Leu Ser Ser Pro Arg Gly Gly Met Lys Lys Lys Thr 
    210                 215                 220                 


Thr His Phe Val Glu Gly Gly Asp Ala Gly Asn Arg Glu Asp Gln Ile 
225                 230                 235                 240 


Asn Arg Leu Ile Arg Arg Met Asn 
                245             


<210>  1538
<211>  266
<212>  PRT
<213>  Homo sapiens

<400>  1538

Met Pro Lys Gly Lys Lys Ala Lys Gly Lys Lys Val Ala Pro Ala Pro 
1               5                   10                  15      


Ala Val Val Lys Lys Gln Glu Ala Lys Lys Val Val Asn Pro Leu Phe 
            20                  25                  30          


Glu Lys Arg Pro Lys Asn Phe Gly Ile Gly Gln Asp Ile Gln Pro Lys 
        35                  40                  45              


Arg Asp Leu Thr Arg Phe Val Lys Trp Pro Arg Tyr Ile Arg Leu Gln 
    50                  55                  60                  


Arg Gln Arg Ala Ile Leu Tyr Lys Arg Leu Lys Val Pro Pro Ala Ile 
65                  70                  75                  80  


Asn Gln Phe Thr Gln Ala Leu Asp Arg Gln Thr Ala Thr Gln Leu Leu 
                85                  90                  95      


Lys Leu Ala His Lys Tyr Arg Pro Glu Thr Lys Gln Glu Lys Lys Gln 
            100                 105                 110         


Arg Leu Leu Ala Arg Ala Glu Lys Lys Ala Ala Gly Lys Gly Asp Val 
        115                 120                 125             


Pro Thr Lys Arg Pro Pro Val Leu Arg Ala Gly Val Asn Thr Val Thr 
    130                 135                 140                 


Thr Leu Val Glu Asn Lys Lys Ala Gln Leu Val Val Ile Ala His Asp 
145                 150                 155                 160 


Val Asp Pro Ile Glu Leu Val Val Phe Leu Pro Ala Leu Cys Arg Lys 
                165                 170                 175     


Met Gly Val Pro Tyr Cys Ile Ile Lys Gly Lys Ala Arg Leu Gly Arg 
            180                 185                 190         


Leu Val His Arg Lys Thr Cys Thr Thr Val Ala Phe Thr Gln Val Asn 
        195                 200                 205             


Ser Glu Asp Lys Gly Ala Leu Ala Lys Leu Val Glu Ala Ile Arg Thr 
    210                 215                 220                 


Asn Tyr Asn Asp Arg Tyr Asp Glu Ile Arg Arg His Trp Gly Gly Asn 
225                 230                 235                 240 


Val Leu Gly Pro Lys Ser Val Ala Arg Ile Ala Lys Leu Glu Lys Ala 
                245                 250                 255     


Lys Ala Lys Glu Leu Ala Thr Lys Leu Gly 
            260                 265     


<210>  1539
<211>  257
<212>  PRT
<213>  Homo sapiens

<400>  1539

Met Gly Arg Val Ile Arg Gly Gln Arg Lys Gly Ala Gly Ser Val Phe 
1               5                   10                  15      


Arg Ala His Val Lys His Arg Lys Gly Ala Ala Arg Leu Arg Ala Val 
            20                  25                  30          


Asp Phe Ala Glu Arg His Gly Tyr Ile Lys Gly Ile Val Lys Asp Ile 
        35                  40                  45              


Ile His Asp Pro Gly Arg Gly Ala Pro Leu Ala Lys Val Val Phe Arg 
    50                  55                  60                  


Asp Pro Tyr Arg Phe Lys Lys Arg Thr Glu Leu Phe Ile Ala Ala Glu 
65                  70                  75                  80  


Gly Ile His Thr Gly Gln Phe Val Tyr Cys Gly Lys Lys Ala Gln Leu 
                85                  90                  95      


Asn Ile Gly Asn Val Leu Pro Val Gly Thr Met Pro Glu Gly Thr Ile 
            100                 105                 110         


Val Cys Cys Leu Glu Glu Lys Pro Gly Asp Arg Gly Lys Leu Ala Arg 
        115                 120                 125             


Ala Ser Gly Asn Tyr Ala Thr Val Ile Ser His Asn Pro Glu Thr Lys 
    130                 135                 140                 


Lys Thr Arg Val Lys Leu Pro Ser Gly Ser Lys Lys Val Ile Ser Ser 
145                 150                 155                 160 


Ala Asn Arg Ala Val Val Gly Val Val Ala Gly Gly Gly Arg Ile Asp 
                165                 170                 175     


Lys Pro Ile Leu Lys Ala Gly Arg Ala Tyr His Lys Tyr Lys Ala Lys 
            180                 185                 190         


Arg Asn Cys Trp Pro Arg Val Arg Gly Val Ala Met Asn Pro Val Glu 
        195                 200                 205             


His Pro Phe Gly Gly Gly Asn His Gln His Ile Gly Lys Pro Ser Thr 
    210                 215                 220                 


Ile Arg Arg Asp Ala Pro Ala Gly Arg Lys Val Gly Leu Ile Ala Ala 
225                 230                 235                 240 


Arg Arg Thr Gly Arg Leu Arg Gly Thr Lys Thr Val Gln Glu Lys Glu 
                245                 250                 255     


Asn 
    


<210>  1540
<211>  293
<212>  PRT
<213>  Homo sapiens

<400>  1540

Met Ala Asp Asp Ala Gly Ala Ala Gly Gly Pro Gly Gly Pro Gly Gly 
1               5                   10                  15      


Pro Gly Met Gly Asn Arg Gly Gly Phe Arg Gly Gly Phe Gly Ser Gly 
            20                  25                  30          


Ile Arg Gly Arg Gly Arg Gly Arg Gly Arg Gly Arg Gly Arg Gly Arg 
        35                  40                  45              


Gly Ala Arg Gly Gly Lys Ala Glu Asp Lys Glu Trp Met Pro Val Thr 
    50                  55                  60                  


Lys Leu Gly Arg Leu Val Lys Asp Met Lys Ile Lys Ser Leu Glu Glu 
65                  70                  75                  80  


Ile Tyr Leu Phe Ser Leu Pro Ile Lys Glu Ser Glu Ile Ile Asp Phe 
                85                  90                  95      


Phe Leu Gly Ala Ser Leu Lys Asp Glu Val Leu Lys Ile Met Pro Val 
            100                 105                 110         


Gln Lys Gln Thr Arg Ala Gly Gln Arg Thr Arg Phe Lys Ala Phe Val 
        115                 120                 125             


Ala Ile Gly Asp Tyr Asn Gly His Val Gly Leu Gly Val Lys Cys Ser 
    130                 135                 140                 


Lys Glu Val Ala Thr Ala Ile Arg Gly Ala Ile Ile Leu Ala Lys Leu 
145                 150                 155                 160 


Ser Ile Val Pro Val Arg Arg Gly Tyr Trp Gly Asn Lys Ile Gly Lys 
                165                 170                 175     


Pro His Thr Val Pro Cys Lys Val Thr Gly Arg Cys Gly Ser Val Leu 
            180                 185                 190         


Val Arg Leu Ile Pro Ala Pro Arg Gly Thr Gly Ile Val Ser Ala Pro 
        195                 200                 205             


Val Pro Lys Lys Leu Leu Met Met Ala Gly Ile Asp Asp Cys Tyr Thr 
    210                 215                 220                 


Ser Ala Arg Gly Cys Thr Ala Thr Leu Gly Asn Phe Ala Lys Ala Thr 
225                 230                 235                 240 


Phe Asp Ala Ile Ser Lys Thr Tyr Ser Tyr Leu Thr Pro Asp Leu Trp 
                245                 250                 255     


Lys Glu Thr Val Phe Thr Lys Ser Pro Tyr Gln Glu Phe Thr Asp His 
            260                 265                 270         


Leu Val Lys Thr His Thr Arg Val Ser Val Gln Arg Thr Gln Ala Pro 
        275                 280                 285             


Ala Val Ala Thr Thr 
    290             


<210>  1541
<211>  264
<212>  PRT
<213>  Homo sapiens

<400>  1541

Met Ala Val Gly Lys Asn Lys Arg Leu Thr Lys Gly Gly Lys Lys Gly 
1               5                   10                  15      


Ala Lys Lys Lys Val Val Asp Pro Phe Ser Lys Lys Asp Trp Tyr Asp 
            20                  25                  30          


Val Lys Ala Pro Ala Met Phe Asn Ile Arg Asn Ile Gly Lys Thr Leu 
        35                  40                  45              


Val Thr Arg Thr Gln Gly Thr Lys Ile Ala Ser Asp Gly Leu Lys Gly 
    50                  55                  60                  


Arg Val Phe Glu Val Ser Leu Ala Asp Leu Gln Asn Asp Glu Val Ala 
65                  70                  75                  80  


Phe Arg Lys Phe Lys Leu Ile Thr Glu Asp Val Gln Gly Lys Asn Cys 
                85                  90                  95      


Leu Thr Asn Phe His Gly Met Asp Leu Thr Arg Asp Lys Met Cys Ser 
            100                 105                 110         


Met Val Lys Lys Trp Gln Thr Met Ile Glu Ala His Val Asp Val Lys 
        115                 120                 125             


Thr Thr Asp Gly Tyr Leu Leu Arg Leu Phe Cys Val Gly Phe Thr Lys 
    130                 135                 140                 


Lys Arg Asn Asn Gln Ile Arg Lys Thr Ser Tyr Ala Gln His Gln Gln 
145                 150                 155                 160 


Val Arg Gln Ile Arg Lys Lys Met Met Glu Ile Met Thr Arg Glu Val 
                165                 170                 175     


Gln Thr Asn Asp Leu Lys Glu Val Val Asn Lys Leu Ile Pro Asp Ser 
            180                 185                 190         


Ile Gly Lys Asp Ile Glu Lys Ala Cys Gln Ser Ile Tyr Pro Leu His 
        195                 200                 205             


Asp Val Phe Val Arg Lys Val Lys Met Leu Lys Lys Pro Lys Phe Glu 
    210                 215                 220                 


Leu Gly Lys Leu Met Glu Leu His Gly Glu Gly Ser Ser Ser Gly Lys 
225                 230                 235                 240 


Ala Thr Gly Asp Glu Thr Gly Ala Lys Val Glu Arg Ala Asp Gly Tyr 
                245                 250                 255     


Glu Pro Pro Val Gln Glu Ser Val 
            260                 


<210>  1542
<211>  1392
<212>  PRT
<213>  Homo sapiens

<400>  1542

Met Ser Met Leu Lys Pro Ser Gly Leu Lys Ala Pro Thr Lys Ile Leu 
1               5                   10                  15      


Lys Pro Gly Ser Thr Ala Leu Lys Thr Pro Thr Ala Val Val Ala Pro 
            20                  25                  30          


Val Glu Lys Thr Ile Ser Ser Glu Lys Ala Ser Ser Thr Pro Ser Ser 
        35                  40                  45              


Glu Thr Gln Glu Glu Phe Val Asp Asp Phe Arg Val Gly Glu Arg Val 
    50                  55                  60                  


Trp Val Asn Gly Asn Lys Pro Gly Phe Ile Gln Phe Leu Gly Glu Thr 
65                  70                  75                  80  


Gln Phe Ala Pro Gly Gln Trp Ala Gly Ile Val Leu Asp Glu Pro Ile 
                85                  90                  95      


Gly Lys Asn Asp Gly Ser Val Ala Gly Val Arg Tyr Phe Gln Cys Glu 
            100                 105                 110         


Pro Leu Lys Gly Ile Phe Thr Arg Pro Ser Lys Leu Thr Arg Lys Val 
        115                 120                 125             


Gln Ala Glu Asp Glu Ala Asn Gly Leu Gln Thr Thr Pro Ala Ser Arg 
    130                 135                 140                 


Ala Thr Ser Pro Leu Cys Thr Ser Thr Ala Ser Met Val Ser Ser Ser 
145                 150                 155                 160 


Pro Ser Thr Pro Ser Asn Ile Pro Gln Lys Pro Ser Gln Pro Ala Ala 
                165                 170                 175     


Lys Glu Pro Ser Ala Thr Pro Pro Ile Ser Asn Leu Thr Lys Thr Ala 
            180                 185                 190         


Ser Glu Ser Ile Ser Asn Leu Ser Glu Ala Gly Ser Ile Lys Lys Gly 
        195                 200                 205             


Glu Arg Glu Leu Lys Ile Gly Asp Arg Val Leu Val Gly Gly Thr Lys 
    210                 215                 220                 


Ala Gly Val Val Arg Phe Leu Gly Glu Thr Asp Phe Ala Lys Gly Glu 
225                 230                 235                 240 


Trp Cys Gly Val Glu Leu Asp Glu Pro Leu Gly Lys Asn Asp Gly Ala 
                245                 250                 255     


Val Ala Gly Thr Arg Tyr Phe Gln Cys Gln Pro Lys Tyr Gly Leu Phe 
            260                 265                 270         


Ala Pro Val His Lys Val Thr Lys Ile Gly Phe Pro Ser Thr Thr Pro 
        275                 280                 285             


Ala Lys Ala Lys Ala Asn Ala Val Arg Arg Val Met Ala Thr Thr Ser 
    290                 295                 300                 


Ala Ser Leu Lys Arg Ser Pro Ser Ala Ser Ser Leu Ser Ser Met Ser 
305                 310                 315                 320 


Ser Val Ala Ser Ser Val Ser Ser Arg Pro Ser Arg Thr Gly Leu Leu 
                325                 330                 335     


Thr Glu Thr Ser Ser Arg Tyr Ala Arg Lys Ile Ser Gly Thr Thr Ala 
            340                 345                 350         


Leu Gln Glu Ala Leu Lys Glu Lys Gln Gln His Ile Glu Gln Leu Leu 
        355                 360                 365             


Ala Glu Arg Asp Leu Glu Arg Ala Glu Val Ala Lys Ala Thr Ser His 
    370                 375                 380                 


Val Gly Glu Ile Glu Gln Glu Leu Ala Leu Ala Arg Asp Gly His Asp 
385                 390                 395                 400 


Gln His Val Leu Glu Leu Glu Ala Lys Met Asp Gln Leu Arg Thr Met 
                405                 410                 415     


Val Glu Ala Ala Asp Arg Glu Lys Val Glu Leu Leu Asn Gln Leu Glu 
            420                 425                 430         


Glu Glu Lys Arg Lys Val Glu Asp Leu Gln Phe Arg Val Glu Glu Glu 
        435                 440                 445             


Ser Ile Thr Lys Gly Asp Leu Glu Val Ala Thr Val Ser Glu Lys Ser 
    450                 455                 460                 


Arg Ile Met Glu Leu Glu Lys Asp Leu Ala Leu Arg Val Gln Glu Val 
465                 470                 475                 480 


Ala Glu Leu Arg Arg Arg Leu Glu Ser Asn Lys Pro Ala Gly Asp Val 
                485                 490                 495     


Asp Met Ser Leu Ser Leu Leu Gln Glu Ile Ser Ser Leu Gln Glu Lys 
            500                 505                 510         


Leu Glu Val Thr Arg Thr Asp His Gln Arg Glu Ile Thr Ser Leu Lys 
        515                 520                 525             


Glu His Phe Gly Ala Arg Glu Glu Thr His Gln Lys Glu Ile Lys Ala 
    530                 535                 540                 


Leu Tyr Thr Ala Thr Glu Lys Leu Ser Lys Glu Asn Glu Ser Leu Lys 
545                 550                 555                 560 


Ser Lys Leu Glu His Ala Asn Lys Glu Asn Ser Asp Val Ile Ala Leu 
                565                 570                 575     


Trp Lys Ser Lys Leu Glu Thr Ala Ile Ala Ser His Gln Gln Ala Met 
            580                 585                 590         


Glu Glu Leu Lys Val Ser Phe Ser Lys Gly Leu Gly Thr Glu Thr Ala 
        595                 600                 605             


Glu Phe Ala Glu Leu Lys Thr Gln Ile Glu Lys Met Arg Leu Asp Tyr 
    610                 615                 620                 


Gln His Glu Ile Glu Asn Leu Gln Asn Gln Gln Asp Ser Glu Arg Ala 
625                 630                 635                 640 


Ala His Ala Lys Glu Met Glu Ala Leu Arg Ala Lys Leu Met Lys Val 
                645                 650                 655     


Ile Lys Glu Lys Glu Asn Ser Leu Glu Ala Ile Arg Ser Lys Leu Asp 
            660                 665                 670         


Lys Ala Glu Asp Gln His Leu Val Glu Met Glu Asp Thr Leu Asn Lys 
        675                 680                 685             


Leu Gln Glu Ala Glu Ile Lys Val Lys Glu Leu Glu Val Leu Gln Ala 
    690                 695                 700                 


Lys Cys Asn Glu Gln Thr Lys Val Ile Asp Asn Phe Thr Ser Gln Leu 
705                 710                 715                 720 


Lys Ala Thr Glu Glu Lys Leu Leu Asp Leu Asp Ala Leu Arg Lys Ala 
                725                 730                 735     


Ser Ser Glu Gly Lys Ser Glu Met Lys Lys Leu Arg Gln Gln Leu Glu 
            740                 745                 750         


Ala Ala Glu Lys Gln Ile Lys His Leu Glu Ile Glu Lys Asn Ala Glu 
        755                 760                 765             


Ser Ser Lys Ala Ser Ser Ile Thr Arg Glu Leu Gln Gly Arg Glu Leu 
    770                 775                 780                 


Lys Leu Thr Asn Leu Gln Glu Asn Leu Ser Glu Val Ser Gln Val Lys 
785                 790                 795                 800 


Glu Thr Leu Glu Lys Glu Leu Gln Ile Leu Lys Glu Lys Phe Ala Glu 
                805                 810                 815     


Ala Ser Glu Glu Ala Val Ser Val Gln Arg Ser Met Gln Glu Thr Val 
            820                 825                 830         


Asn Lys Leu His Gln Lys Glu Glu Gln Phe Asn Met Leu Ser Ser Asp 
        835                 840                 845             


Leu Glu Lys Leu Arg Glu Asn Leu Ala Asp Met Glu Ala Lys Phe Arg 
    850                 855                 860                 


Glu Lys Asp Glu Arg Glu Glu Gln Leu Ile Lys Ala Lys Glu Lys Leu 
865                 870                 875                 880 


Glu Asn Asp Ile Ala Glu Ile Met Lys Met Ser Gly Asp Asn Ser Ser 
                885                 890                 895     


Gln Leu Thr Lys Met Asn Asp Glu Leu Arg Leu Lys Glu Arg Asp Val 
            900                 905                 910         


Glu Glu Leu Gln Leu Lys Leu Thr Lys Ala Asn Glu Asn Ala Ser Phe 
        915                 920                 925             


Leu Gln Lys Ser Ile Glu Asp Met Thr Val Lys Ala Glu Gln Ser Gln 
    930                 935                 940                 


Gln Glu Ala Ala Lys Lys His Glu Glu Glu Lys Lys Glu Leu Glu Arg 
945                 950                 955                 960 


Lys Leu Ser Asp Leu Glu Lys Lys Met Glu Thr Ser His Asn Gln Cys 
                965                 970                 975     


Gln Glu Leu Lys Ala Arg Tyr Glu Arg Ala Thr Ser Glu Thr Lys Thr 
            980                 985                 990         


Lys His Glu Glu Ile Leu Gln Asn  Leu Gln Lys Thr Leu  Leu Asp Thr 
        995                 1000                 1005             


Glu Asp  Lys Leu Lys Gly Ala  Arg Glu Glu Asn Ser  Gly Leu Leu 
    1010                 1015                 1020             


Gln Glu  Leu Glu Glu Leu Arg  Lys Gln Ala Asp Lys  Ala Lys Ala 
    1025                 1030                 1035             


Ala Gln  Thr Ala Glu Asp Ala  Met Gln Ile Met Glu  Gln Met Thr 
    1040                 1045                 1050             


Lys Glu  Lys Thr Glu Thr Leu  Ala Ser Leu Glu Asp  Thr Lys Gln 
    1055                 1060                 1065             


Thr Asn  Ala Lys Leu Gln Asn  Glu Leu Asp Thr Leu  Lys Glu Asn 
    1070                 1075                 1080             


Asn Leu  Lys Asn Val Glu Glu  Leu Asn Lys Ser Lys  Glu Leu Leu 
    1085                 1090                 1095             


Thr Val  Glu Asn Gln Lys Met  Glu Glu Phe Arg Lys  Glu Ile Glu 
    1100                 1105                 1110             


Thr Leu  Lys Gln Ala Ala Ala  Gln Lys Ser Gln Gln  Leu Ser Ala 
    1115                 1120                 1125             


Leu Gln  Glu Glu Asn Val Lys  Leu Ala Glu Glu Leu  Gly Arg Ser 
    1130                 1135                 1140             


Arg Asp  Glu Val Thr Ser His  Gln Lys Leu Glu Glu  Glu Arg Ser 
    1145                 1150                 1155             


Val Leu  Asn Asn Gln Leu Leu  Glu Met Lys Lys Arg  Glu Ser Lys 
    1160                 1165                 1170             


Phe Ile  Lys Asp Ala Asp Glu  Glu Lys Ala Ser Leu  Gln Lys Ser 
    1175                 1180                 1185             


Ile Ser  Ile Thr Ser Ala Leu  Leu Thr Glu Lys Asp  Ala Glu Leu 
    1190                 1195                 1200             


Glu Lys  Leu Arg Asn Glu Val  Thr Val Leu Arg Gly  Glu Asn Ala 
    1205                 1210                 1215             


Ser Ala  Lys Ser Leu His Ser  Val Val Gln Thr Leu  Glu Ser Asp 
    1220                 1225                 1230             


Lys Val  Lys Leu Glu Leu Lys  Val Lys Asn Leu Glu  Leu Gln Leu 
    1235                 1240                 1245             


Lys Glu  Asn Lys Arg Gln Leu  Ser Ser Ser Ser Gly  Asn Thr Asp 
    1250                 1255                 1260             


Thr Gln  Ala Asp Glu Asp Glu  Arg Ala Gln Glu Ser  Gln Ile Asp 
    1265                 1270                 1275             


Phe Leu  Asn Ser Val Ile Val  Asp Leu Gln Arg Lys  Asn Gln Asp 
    1280                 1285                 1290             


Leu Lys  Met Lys Val Glu Met  Met Ser Glu Ala Ala  Leu Asn Gly 
    1295                 1300                 1305             


Asn Gly  Asp Asp Leu Asn Asn  Tyr Asp Ser Asp Asp  Gln Glu Lys 
    1310                 1315                 1320             


Gln Ser  Lys Lys Lys Pro Arg  Leu Phe Cys Asp Ile  Cys Asp Cys 
    1325                 1330                 1335             


Phe Asp  Leu His Asp Thr Glu  Asp Cys Pro Thr Gln  Ala Gln Met 
    1340                 1345                 1350             


Ser Glu  Asp Pro Pro His Ser  Thr His His Gly Ser  Arg Gly Glu 
    1355                 1360                 1365             


Glu Arg  Pro Tyr Cys Glu Ile  Cys Glu Met Phe Gly  His Trp Ala 
    1370                 1375                 1380             


Thr Asn  Cys Asn Asp Asp Glu  Thr Phe 
    1385                 1390         


<210>  1543
<211>  968
<212>  PRT
<213>  Homo sapiens

<400>  1543

Met Ala Phe Ala Asn Phe Arg Arg Ile Leu Arg Leu Ser Thr Phe Glu 
1               5                   10                  15      


Lys Arg Lys Ser Arg Glu Tyr Glu His Val Arg Arg Asp Leu Asp Pro 
            20                  25                  30          


Asn Glu Val Trp Glu Ile Val Gly Glu Leu Gly Asp Gly Ala Phe Gly 
        35                  40                  45              


Lys Val Tyr Lys Ala Lys Asn Lys Glu Thr Gly Ala Leu Ala Ala Ala 
    50                  55                  60                  


Lys Val Ile Glu Thr Lys Ser Glu Glu Glu Leu Glu Asp Tyr Ile Val 
65                  70                  75                  80  


Glu Ile Glu Ile Leu Ala Thr Cys Asp His Pro Tyr Ile Val Lys Leu 
                85                  90                  95      


Leu Gly Ala Tyr Tyr His Asp Gly Lys Leu Trp Ile Met Ile Glu Phe 
            100                 105                 110         


Cys Pro Gly Gly Ala Val Asp Ala Ile Met Leu Glu Leu Asp Arg Gly 
        115                 120                 125             


Leu Thr Glu Pro Gln Ile Gln Val Val Cys Arg Gln Met Leu Glu Ala 
    130                 135                 140                 


Leu Asn Phe Leu His Ser Lys Arg Ile Ile His Arg Asp Leu Lys Ala 
145                 150                 155                 160 


Gly Asn Val Leu Met Thr Leu Glu Gly Asp Ile Arg Leu Ala Asp Phe 
                165                 170                 175     


Gly Val Ser Ala Lys Asn Leu Lys Thr Leu Gln Lys Arg Asp Ser Phe 
            180                 185                 190         


Ile Gly Thr Pro Tyr Trp Met Ala Pro Glu Val Val Met Cys Glu Thr 
        195                 200                 205             


Met Lys Asp Thr Pro Tyr Asp Tyr Lys Ala Asp Ile Trp Ser Leu Gly 
    210                 215                 220                 


Ile Thr Leu Ile Glu Met Ala Gln Ile Glu Pro Pro His His Glu Leu 
225                 230                 235                 240 


Asn Pro Met Arg Val Leu Leu Lys Ile Ala Lys Ser Asp Pro Pro Thr 
                245                 250                 255     


Leu Leu Thr Pro Ser Lys Trp Ser Val Glu Phe Arg Asp Phe Leu Lys 
            260                 265                 270         


Ile Ala Leu Asp Lys Asn Pro Glu Thr Arg Pro Ser Ala Ala Gln Leu 
        275                 280                 285             


Leu Glu His Pro Phe Val Ser Ser Ile Thr Ser Asn Lys Ala Leu Arg 
    290                 295                 300                 


Glu Leu Val Ala Glu Ala Lys Ala Glu Val Met Glu Glu Ile Glu Asp 
305                 310                 315                 320 


Gly Arg Asp Glu Gly Glu Glu Glu Asp Ala Val Asp Ala Ala Ser Thr 
                325                 330                 335     


Leu Glu Asn His Thr Gln Asn Ser Ser Glu Val Ser Pro Pro Ser Leu 
            340                 345                 350         


Asn Ala Asp Lys Pro Leu Glu Glu Ser Pro Ser Thr Pro Leu Ala Pro 
        355                 360                 365             


Ser Gln Ser Gln Asp Ser Val Asn Glu Pro Cys Ser Gln Pro Ser Gly 
    370                 375                 380                 


Asp Arg Ser Leu Gln Thr Thr Ser Pro Pro Val Val Ala Pro Gly Asn 
385                 390                 395                 400 


Glu Asn Gly Leu Ala Val Pro Val Pro Leu Arg Lys Ser Arg Pro Val 
                405                 410                 415     


Ser Met Asp Ala Arg Ile Gln Val Ala Gln Glu Lys Gln Val Ala Glu 
            420                 425                 430         


Gln Gly Gly Asp Leu Ser Pro Ala Ala Asn Arg Ser Gln Lys Ala Ser 
        435                 440                 445             


Gln Ser Arg Pro Asn Ser Ser Ala Leu Glu Thr Leu Gly Gly Glu Lys 
    450                 455                 460                 


Leu Ala Asn Gly Ser Leu Glu Pro Pro Ala Gln Ala Ala Pro Gly Pro 
465                 470                 475                 480 


Ser Lys Arg Asp Ser Asp Cys Ser Ser Leu Cys Thr Ser Glu Ser Met 
                485                 490                 495     


Asp Tyr Gly Thr Asn Leu Ser Thr Asp Leu Ser Leu Asn Lys Glu Met 
            500                 505                 510         


Gly Ser Leu Ser Ile Lys Asp Pro Lys Leu Tyr Lys Lys Thr Leu Lys 
        515                 520                 525             


Arg Thr Arg Lys Phe Val Val Asp Gly Val Glu Val Ser Ile Thr Thr 
    530                 535                 540                 


Ser Lys Ile Ile Ser Glu Asp Glu Lys Lys Asp Glu Glu Met Arg Phe 
545                 550                 555                 560 


Leu Arg Arg Gln Glu Leu Arg Glu Leu Arg Leu Leu Gln Lys Glu Glu 
                565                 570                 575     


His Arg Asn Gln Thr Gln Leu Ser Asn Lys His Glu Leu Gln Leu Glu 
            580                 585                 590         


Gln Met His Lys Arg Phe Glu Gln Glu Ile Asn Ala Lys Lys Lys Phe 
        595                 600                 605             


Phe Asp Thr Glu Leu Glu Asn Leu Glu Arg Gln Gln Lys Gln Gln Val 
    610                 615                 620                 


Glu Lys Met Glu Gln Asp His Ala Val Arg Arg Arg Glu Glu Ala Arg 
625                 630                 635                 640 


Arg Ile Arg Leu Glu Gln Asp Arg Asp Tyr Thr Arg Phe Gln Glu Gln 
                645                 650                 655     


Leu Lys Leu Met Lys Lys Glu Val Lys Asn Glu Val Glu Lys Leu Pro 
            660                 665                 670         


Arg Gln Gln Arg Lys Glu Ser Met Lys Gln Lys Met Glu Glu His Thr 
        675                 680                 685             


Gln Lys Lys Gln Leu Leu Asp Arg Asp Phe Val Ala Lys Gln Lys Glu 
    690                 695                 700                 


Asp Leu Glu Leu Ala Met Lys Arg Leu Thr Thr Asp Asn Arg Arg Glu 
705                 710                 715                 720 


Ile Cys Asp Lys Glu Arg Glu Cys Leu Met Lys Lys Gln Glu Leu Leu 
                725                 730                 735     


Arg Asp Arg Glu Ala Ala Leu Trp Glu Met Glu Glu His Gln Leu Gln 
            740                 745                 750         


Glu Arg His Gln Leu Val Lys Gln Gln Leu Lys Asp Gln Tyr Phe Leu 
        755                 760                 765             


Gln Arg His Glu Leu Leu Arg Lys His Glu Lys Glu Arg Glu Gln Met 
    770                 775                 780                 


Gln Arg Tyr Asn Gln Arg Met Ile Glu Gln Leu Lys Val Arg Gln Gln 
785                 790                 795                 800 


Gln Glu Lys Ala Arg Leu Pro Lys Ile Gln Arg Ser Glu Gly Lys Thr 
                805                 810                 815     


Arg Met Ala Met Tyr Lys Lys Ser Leu His Ile Asn Gly Gly Gly Ser 
            820                 825                 830         


Ala Ala Glu Gln Arg Glu Lys Ile Lys Gln Phe Ser Gln Gln Glu Glu 
        835                 840                 845             


Lys Arg Gln Lys Ser Glu Arg Leu Gln Gln Gln Gln Lys His Glu Asn 
    850                 855                 860                 


Gln Met Arg Asp Met Leu Ala Gln Cys Glu Ser Asn Met Ser Glu Leu 
865                 870                 875                 880 


Gln Gln Leu Gln Asn Glu Lys Cys His Leu Leu Val Glu His Glu Thr 
                885                 890                 895     


Gln Lys Leu Lys Ala Leu Asp Glu Ser His Asn Gln Asn Leu Lys Glu 
            900                 905                 910         


Trp Arg Asp Lys Leu Arg Pro Arg Lys Lys Ala Leu Glu Glu Asp Leu 
        915                 920                 925             


Asn Gln Lys Lys Arg Glu Gln Glu Met Phe Phe Lys Leu Ser Glu Glu 
    930                 935                 940                 


Ala Glu Cys Pro Asn Pro Ser Thr Pro Ser Lys Ala Ala Lys Phe Phe 
945                 950                 955                 960 


Pro Tyr Ser Ser Ala Asp Ala Ser 
                965             


<210>  1544
<211>  264
<212>  PRT
<213>  Homo sapiens

<400>  1544

Met Glu Ser Gly Lys Thr Ala Ser Pro Lys Ser Met Pro Lys Asp Ala 
1               5                   10                  15      


Gln Met Met Ala Gln Ile Leu Lys Asp Met Gly Ile Thr Glu Tyr Glu 
            20                  25                  30          


Pro Arg Val Ile Asn Gln Met Leu Glu Phe Ala Phe Arg Tyr Val Thr 
        35                  40                  45              


Thr Ile Leu Asp Asp Ala Lys Ile Tyr Ser Ser His Ala Lys Lys Ala 
    50                  55                  60                  


Thr Val Asp Ala Asp Asp Val Arg Leu Ala Ile Gln Cys Arg Ala Asp 
65                  70                  75                  80  


Gln Ser Phe Thr Ser Pro Pro Pro Arg Asp Phe Leu Leu Asp Ile Ala 
                85                  90                  95      


Arg Gln Arg Asn Gln Thr Pro Leu Pro Leu Ile Lys Pro Tyr Ser Gly 
            100                 105                 110         


Pro Arg Leu Pro Pro Asp Arg Tyr Cys Leu Thr Ala Pro Asn Tyr Arg 
        115                 120                 125             


Leu Lys Ser Leu Gln Lys Lys Ala Ser Thr Ser Ala Gly Arg Ile Thr 
    130                 135                 140                 


Val Pro Arg Leu Ser Val Gly Ser Val Thr Ser Arg Pro Ser Thr Pro 
145                 150                 155                 160 


Thr Leu Gly Thr Pro Thr Pro Gln Thr Met Ser Val Ser Thr Lys Val 
                165                 170                 175     


Gly Thr Pro Met Ser Leu Thr Gly Gln Arg Phe Thr Val Gln Met Pro 
            180                 185                 190         


Thr Ser Gln Ser Pro Ala Val Lys Ala Ser Ile Pro Ala Thr Ser Ala 
        195                 200                 205             


Val Gln Asn Val Leu Ile Asn Pro Ser Leu Ile Gly Ser Lys Asn Ile 
    210                 215                 220                 


Phe Ile Thr Thr Asn Met Met Ser Ser Gln Asn Thr Ala Asn Glu Ser 
225                 230                 235                 240 


Ser Asn Ala Leu Lys Arg Lys Arg Glu Asp Asp Asp Asp Asp Asp Asp 
                245                 250                 255     


Asp Asp Asp Asp Tyr Asp Asn Leu 
            260                 


<210>  1545
<211>  198
<212>  PRT
<213>  Homo sapiens

<400>  1545

Met Ala Ser Gly Asn Ala Arg Ile Gly Lys Pro Ala Pro Asp Phe Lys 
1               5                   10                  15      


Ala Thr Ala Val Val Asp Gly Ala Phe Lys Glu Val Lys Leu Ser Asp 
            20                  25                  30          


Tyr Lys Gly Lys Tyr Val Val Leu Phe Phe Tyr Pro Leu Asp Phe Thr 
        35                  40                  45              


Phe Val Cys Pro Thr Glu Ile Ile Ala Phe Ser Asn Arg Ala Glu Asp 
    50                  55                  60                  


Phe Arg Lys Leu Gly Cys Glu Val Leu Gly Val Ser Val Asp Ser Gln 
65                  70                  75                  80  


Phe Thr His Leu Ala Trp Ile Asn Thr Pro Arg Lys Glu Gly Gly Leu 
                85                  90                  95      


Gly Pro Leu Asn Ile Pro Leu Leu Ala Asp Val Thr Arg Arg Leu Ser 
            100                 105                 110         


Glu Asp Tyr Gly Val Leu Lys Thr Asp Glu Gly Ile Ala Tyr Arg Gly 
        115                 120                 125             


Leu Phe Ile Ile Asp Gly Lys Gly Val Leu Arg Gln Ile Thr Val Asn 
    130                 135                 140                 


Asp Leu Pro Val Gly Arg Ser Val Asp Glu Ala Leu Arg Leu Val Gln 
145                 150                 155                 160 


Ala Phe Gln Tyr Thr Asp Glu His Gly Glu Val Cys Pro Ala Gly Trp 
                165                 170                 175     


Lys Pro Gly Ser Asp Thr Ile Lys Pro Asn Val Asp Asp Ser Lys Glu 
            180                 185                 190         


Tyr Phe Ser Lys His Asn 
        195             


<210>  1546
<211>  761
<212>  PRT
<213>  Homo sapiens

<400>  1546

Met Asp Ser Gly Gly Gly Ser Leu Gly Leu His Thr Pro Asp Ser Arg 
1               5                   10                  15      


Met Ala His Thr Met Ile Met Gln Asp Phe Val Ala Gly Met Ala Gly 
            20                  25                  30          


Thr Ala His Ile Asp Gly Asp His Ile Val Val Ser Val Pro Glu Ala 
        35                  40                  45              


Val Leu Val Ser Asp Val Val Thr Asp Asp Gly Ile Thr Leu Asp His 
    50                  55                  60                  


Gly Leu Ala Ala Glu Val Val His Gly Pro Asp Ile Ile Thr Glu Thr 
65                  70                  75                  80  


Asp Val Val Thr Glu Gly Val Ile Val Pro Glu Ala Val Leu Glu Ala 
                85                  90                  95      


Asp Val Ala Ile Glu Glu Asp Leu Glu Glu Asp Asp Gly Asp His Ile 
            100                 105                 110         


Leu Thr Ser Glu Leu Ile Thr Glu Thr Val Arg Val Pro Glu Gln Val 
        115                 120                 125             


Phe Val Ala Asp Leu Val Thr Gly Pro Asn Gly His Leu Glu His Val 
    130                 135                 140                 


Val Gln Asp Cys Val Ser Gly Val Asp Ser Pro Thr Met Val Ser Glu 
145                 150                 155                 160 


Glu Val Leu Val Thr Asn Ser Asp Thr Glu Thr Val Ile Gln Ala Ala 
                165                 170                 175     


Gly Gly Val Pro Gly Ser Thr Val Thr Ile Lys Thr Glu Asp Asp Asp 
            180                 185                 190         


Asp Asp Asp Val Lys Ser Thr Ser Glu Asp Tyr Leu Met Ile Ser Leu 
        195                 200                 205             


Asp Asp Val Gly Glu Lys Leu Glu His Met Gly Asn Thr Pro Leu Lys 
    210                 215                 220                 


Ile Gly Ser Asp Gly Ser Gln Glu Asp Ala Lys Glu Asp Gly Phe Gly 
225                 230                 235                 240 


Ser Glu Val Ile Lys Val Tyr Ile Phe Lys Ala Glu Ala Glu Asp Asp 
                245                 250                 255     


Val Glu Ile Gly Gly Thr Glu Ile Val Thr Glu Ser Glu Tyr Thr Ser 
            260                 265                 270         


Gly His Ser Val Ala Gly Val Leu Asp Gln Ser Arg Met Gln Arg Glu 
        275                 280                 285             


Lys Met Val Tyr Met Ala Val Lys Asp Ser Ser Gln Glu Glu Asp Asp 
    290                 295                 300                 


Ile Arg Asp Glu Arg Arg Val Ser Arg Arg Tyr Glu Asp Cys Gln Ala 
305                 310                 315                 320 


Ser Gly Asn Thr Leu Asp Ser Ala Leu Glu Ser Arg Ser Ser Thr Ala 
                325                 330                 335     


Ala Gln Tyr Leu Gln Ile Cys Asp Gly Ile Asn Thr Asn Lys Val Leu 
            340                 345                 350         


Lys Gln Lys Ala Lys Lys Arg Arg Arg Gly Glu Thr Arg Gln Trp Gln 
        355                 360                 365             


Thr Ala Val Ile Ile Gly Pro Asp Gly Gln Pro Leu Thr Val Tyr Pro 
    370                 375                 380                 


Cys His Ile Cys Thr Lys Lys Phe Lys Ser Arg Gly Phe Leu Lys Arg 
385                 390                 395                 400 


His Met Lys Asn His Pro Asp His Leu Met Arg Lys Lys Tyr Gln Cys 
                405                 410                 415     


Thr Asp Cys Asp Phe Thr Thr Asn Lys Lys Val Ser Phe His Asn His 
            420                 425                 430         


Leu Glu Ser His Lys Leu Ile Asn Lys Val Asp Lys Thr His Glu Phe 
        435                 440                 445             


Thr Glu Tyr Thr Arg Arg Tyr Arg Glu Ala Ser Pro Leu Ser Ser Asn 
    450                 455                 460                 


Lys Leu Ile Leu Arg Asp Lys Glu Pro Lys Met His Lys Cys Lys Tyr 
465                 470                 475                 480 


Cys Asp Tyr Glu Thr Ala Glu Gln Gly Leu Leu Asn Arg His Leu Leu 
                485                 490                 495     


Ala Val His Ser Lys Asn Phe Pro His Val Cys Val Glu Cys Gly Lys 
            500                 505                 510         


Gly Phe Arg His Pro Ser Glu Leu Lys Lys His Met Arg Thr His Thr 
        515                 520                 525             


Gly Glu Lys Pro Tyr Gln Cys Gln Tyr Cys Ile Phe Arg Cys Ala Asp 
    530                 535                 540                 


Gln Ser Asn Leu Lys Thr His Ile Lys Ser Lys His Gly Asn Asn Leu 
545                 550                 555                 560 


Pro Tyr Lys Cys Glu His Cys Pro Gln Ala Phe Gly Asp Glu Arg Glu 
                565                 570                 575     


Leu Gln Arg His Leu Asp Leu Phe Gln Gly His Lys Thr His Gln Cys 
            580                 585                 590         


Pro His Cys Asp His Lys Ser Thr Asn Ser Ser Asp Leu Lys Arg His 
        595                 600                 605             


Ile Ile Ser Val His Thr Lys Asp Phe Pro His Lys Cys Glu Val Cys 
    610                 615                 620                 


Asp Lys Gly Phe His Arg Pro Ser Glu Leu Lys Lys His Ser Asp Ile 
625                 630                 635                 640 


His Lys Gly Arg Lys Ile His Gln Cys Arg His Cys Asp Phe Lys Thr 
                645                 650                 655     


Ser Asp Pro Phe Ile Leu Ser Gly His Ile Leu Ser Val His Thr Lys 
            660                 665                 670         


Asp Gln Pro Leu Lys Cys Lys Arg Cys Lys Arg Gly Phe Arg Gln Gln 
        675                 680                 685             


Asn Glu Leu Lys Lys His Met Lys Thr His Thr Gly Arg Lys Ile Tyr 
    690                 695                 700                 


Gln Cys Glu Tyr Cys Glu Tyr Ser Thr Thr Asp Ala Ser Gly Phe Lys 
705                 710                 715                 720 


Arg His Val Ile Ser Ile His Thr Lys Asp Tyr Pro His Arg Cys Glu 
                725                 730                 735     


Phe Cys Lys Lys Gly Phe Arg Arg Pro Ser Glu Lys Asn Gln His Ile 
            740                 745                 750         


Met Arg His His Lys Glu Ala Leu Met 
        755                 760     


<210>  1547
<211>  235
<212>  PRT
<213>  Homo sapiens

<400>  1547

Met Asn Ile Arg Asn Ala Arg Pro Glu Asp Leu Met Asn Met Gln His 
1               5                   10                  15      


Cys Asn Leu Leu Cys Leu Pro Glu Asn Tyr Gln Met Lys Tyr Tyr Phe 
            20                  25                  30          


Tyr His Gly Leu Ser Trp Pro Gln Leu Ser Tyr Ile Ala Glu Asp Glu 
        35                  40                  45              


Asn Gly Lys Ile Val Gly Tyr Val Leu Ala Lys Met Glu Glu Asp Pro 
    50                  55                  60                  


Asp Asp Val Pro His Gly His Ile Thr Ser Leu Ala Val Lys Arg Ser 
65                  70                  75                  80  


His Arg Arg Leu Gly Leu Ala Gln Lys Leu Met Asp Gln Ala Ser Arg 
                85                  90                  95      


Ala Met Ile Glu Asn Phe Asn Ala Lys Tyr Val Ser Leu His Val Arg 
            100                 105                 110         


Lys Ser Asn Arg Ala Ala Leu His Leu Tyr Ser Asn Thr Leu Asn Phe 
        115                 120                 125             


Gln Ile Ser Glu Val Glu Pro Lys Tyr Tyr Ala Asp Gly Glu Asp Ala 
    130                 135                 140                 


Tyr Ala Met Lys Arg Asp Leu Thr Gln Met Ala Asp Glu Leu Arg Arg 
145                 150                 155                 160 


His Leu Glu Leu Lys Glu Lys Gly Arg His Val Val Leu Gly Ala Ile 
                165                 170                 175     


Glu Asn Lys Val Glu Ser Lys Gly Asn Ser Pro Pro Ser Ser Gly Glu 
            180                 185                 190         


Ala Cys Arg Glu Glu Lys Gly Leu Ala Ala Glu Asp Ser Gly Gly Asp 
        195                 200                 205             


Ser Lys Asp Leu Ser Glu Val Ser Glu Thr Thr Glu Ser Thr Asp Val 
    210                 215                 220                 


Lys Asp Ser Ser Glu Ala Ser Asp Ser Ala Ser 
225                 230                 235 


<210>  1548
<211>  574
<212>  PRT
<213>  Homo sapiens

<400>  1548

Met Glu Ala Ser Leu Gly Ile Gln Met Asp Glu Pro Met Ala Phe Ser 
1               5                   10                  15      


Pro Gln Arg Asp Arg Phe Gln Ala Glu Gly Ser Leu Lys Lys Asn Glu 
            20                  25                  30          


Gln Asn Phe Lys Leu Ala Gly Val Lys Lys Asp Ile Glu Lys Leu Tyr 
        35                  40                  45              


Glu Ala Val Pro Gln Leu Ser Asn Val Phe Lys Ile Glu Asp Lys Ile 
    50                  55                  60                  


Gly Glu Gly Thr Phe Ser Ser Val Tyr Leu Ala Thr Ala Gln Leu Gln 
65                  70                  75                  80  


Val Gly Pro Glu Glu Lys Ile Ala Leu Lys His Leu Ile Pro Thr Ser 
                85                  90                  95      


His Pro Ile Arg Ile Ala Ala Glu Leu Gln Cys Leu Thr Val Ala Gly 
            100                 105                 110         


Gly Gln Asp Asn Val Met Gly Val Lys Tyr Cys Phe Arg Lys Asn Asp 
        115                 120                 125             


His Val Val Ile Ala Met Pro Tyr Leu Glu His Glu Ser Phe Leu Asp 
    130                 135                 140                 


Ile Leu Asn Ser Leu Ser Phe Gln Glu Val Arg Glu Tyr Met Leu Asn 
145                 150                 155                 160 


Leu Phe Lys Ala Leu Lys Arg Ile His Gln Phe Gly Ile Val His Arg 
                165                 170                 175     


Asp Val Lys Pro Ser Asn Phe Leu Tyr Asn Arg Arg Leu Lys Lys Tyr 
            180                 185                 190         


Ala Leu Val Asp Phe Gly Leu Ala Gln Gly Thr His Asp Thr Lys Ile 
        195                 200                 205             


Glu Leu Leu Lys Phe Val Gln Ser Glu Ala Gln Gln Glu Arg Cys Ser 
    210                 215                 220                 


Gln Asn Lys Ser His Ile Ile Thr Gly Asn Lys Ile Pro Leu Ser Gly 
225                 230                 235                 240 


Pro Val Pro Lys Glu Leu Asp Gln Gln Ser Thr Thr Lys Ala Ser Val 
                245                 250                 255     


Lys Arg Pro Tyr Thr Asn Ala Gln Ile Gln Ile Lys Gln Gly Lys Asp 
            260                 265                 270         


Gly Lys Glu Gly Ser Val Gly Leu Ser Val Gln Arg Ser Val Phe Gly 
        275                 280                 285             


Glu Arg Asn Phe Asn Ile His Ser Ser Ile Ser His Glu Ser Pro Ala 
    290                 295                 300                 


Val Lys Leu Met Lys Gln Ser Lys Thr Val Asp Val Leu Ser Arg Lys 
305                 310                 315                 320 


Leu Ala Thr Lys Lys Lys Ala Ile Ser Thr Lys Val Met Asn Ser Ala 
                325                 330                 335     


Val Met Arg Lys Thr Ala Ser Ser Cys Pro Ala Ser Leu Thr Cys Asp 
            340                 345                 350         


Cys Tyr Ala Thr Asp Lys Val Cys Ser Ile Cys Leu Ser Arg Arg Gln 
        355                 360                 365             


Gln Val Ala Pro Arg Ala Gly Thr Pro Gly Phe Arg Ala Pro Glu Val 
    370                 375                 380                 


Leu Thr Lys Cys Pro Asn Gln Thr Thr Ala Ile Asp Met Trp Ser Ala 
385                 390                 395                 400 


Gly Val Ile Phe Leu Ser Leu Leu Ser Gly Arg Tyr Pro Phe Tyr Lys 
                405                 410                 415     


Ala Ser Asp Asp Leu Thr Ala Leu Ala Gln Ile Met Thr Ile Arg Gly 
            420                 425                 430         


Ser Arg Glu Thr Ile Gln Ala Ala Lys Thr Phe Gly Lys Ser Ile Leu 
        435                 440                 445             


Cys Ser Lys Glu Val Pro Ala Gln Asp Leu Arg Lys Leu Cys Glu Arg 
    450                 455                 460                 


Leu Arg Gly Met Asp Ser Ser Thr Pro Lys Leu Thr Ser Asp Ile Gln 
465                 470                 475                 480 


Gly His Ala Ser His Gln Pro Ala Ile Ser Glu Lys Thr Asp His Lys 
                485                 490                 495     


Ala Ser Cys Leu Val Gln Thr Pro Pro Gly Gln Tyr Ser Gly Asn Ser 
            500                 505                 510         


Phe Lys Lys Gly Asp Ser Asn Ser Cys Glu His Cys Phe Asp Glu Tyr 
        515                 520                 525             


Asn Thr Asn Leu Glu Gly Trp Asn Glu Val Pro Asp Glu Ala Tyr Asp 
    530                 535                 540                 


Leu Leu Asp Lys Leu Leu Asp Leu Asn Pro Ala Ser Arg Ile Thr Ala 
545                 550                 555                 560 


Glu Glu Ala Leu Leu His Pro Phe Phe Lys Asp Met Ser Leu 
                565                 570                 


<210>  1549
<211>  352
<212>  PRT
<213>  Homo sapiens

<400>  1549

Met Ala Ser Arg Lys Glu Gly Thr Gly Ser Thr Ala Thr Ser Ser Ser 
1               5                   10                  15      


Ser Thr Ala Gly Ala Ala Gly Lys Gly Lys Gly Lys Gly Gly Ser Gly 
            20                  25                  30          


Asp Ser Ala Val Lys Gln Val Gln Ile Asp Gly Leu Val Val Leu Lys 
        35                  40                  45              


Ile Ile Lys His Tyr Gln Glu Glu Gly Gln Gly Thr Glu Val Val Gln 
    50                  55                  60                  


Gly Val Leu Leu Gly Leu Val Val Glu Asp Arg Leu Glu Ile Thr Asn 
65                  70                  75                  80  


Cys Phe Pro Phe Pro Gln His Thr Glu Asp Asp Ala Asp Phe Asp Glu 
                85                  90                  95      


Val Gln Tyr Gln Met Glu Met Met Arg Ser Leu Arg His Val Asn Ile 
            100                 105                 110         


Asp His Leu His Val Gly Trp Tyr Gln Ser Thr Tyr Tyr Gly Ser Phe 
        115                 120                 125             


Val Thr Arg Ala Leu Leu Asp Ser Gln Phe Ser Tyr Gln His Ala Ile 
    130                 135                 140                 


Glu Glu Ser Val Val Leu Ile Tyr Asp Pro Ile Lys Thr Ala Gln Gly 
145                 150                 155                 160 


Ser Leu Ser Leu Lys Ala Tyr Arg Leu Thr Pro Lys Leu Met Glu Val 
                165                 170                 175     


Cys Lys Glu Lys Asp Phe Ser Pro Glu Ala Leu Lys Lys Ala Asn Ile 
            180                 185                 190         


Thr Phe Glu Tyr Met Phe Glu Glu Val Pro Ile Val Ile Lys Asn Ser 
        195                 200                 205             


His Leu Ile Asn Val Leu Met Trp Glu Leu Glu Lys Lys Ser Ala Val 
    210                 215                 220                 


Ala Asp Lys His Glu Leu Leu Ser Leu Ala Ser Ser Asn His Leu Gly 
225                 230                 235                 240 


Lys Asn Leu Gln Leu Leu Met Asp Arg Val Asp Glu Met Ser Gln Asp 
                245                 250                 255     


Ile Val Lys Tyr Asn Thr Tyr Met Arg Asn Thr Ser Lys Gln Gln Gln 
            260                 265                 270         


Gln Lys His Gln Tyr Gln Gln Arg Arg Gln Gln Glu Asn Met Gln Arg 
        275                 280                 285             


Gln Ser Arg Gly Glu Pro Pro Leu Pro Glu Glu Asp Leu Ser Lys Leu 
    290                 295                 300                 


Phe Lys Pro Pro Gln Pro Pro Ala Arg Met Asp Ser Leu Leu Ile Ala 
305                 310                 315                 320 


Gly Gln Ile Asn Thr Tyr Cys Gln Asn Ile Lys Glu Phe Thr Ala Gln 
                325                 330                 335     


Asn Leu Gly Lys Leu Phe Met Ala Gln Ala Leu Gln Glu Tyr Asn Asn 
            340                 345                 350         


<210>  1550
<211>  1462
<212>  PRT
<213>  Homo sapiens

<400>  1550

Met Ser Lys Val Ile Gln Lys Lys Asn His Trp Thr Ser Arg Val His 
1               5                   10                  15      


Glu Cys Thr Val Lys Arg Gly Pro Gln Gly Glu Leu Gly Val Thr Val 
            20                  25                  30          


Leu Gly Gly Ala Glu His Gly Glu Phe Pro Tyr Val Gly Ala Val Ala 
        35                  40                  45              


Ala Val Glu Ala Ala Gly Leu Pro Gly Gly Gly Glu Gly Pro Arg Leu 
    50                  55                  60                  


Gly Glu Gly Glu Leu Leu Leu Glu Val Gln Gly Val Arg Val Ser Gly 
65                  70                  75                  80  


Leu Pro Arg Tyr Asp Val Leu Gly Val Ile Asp Ser Cys Lys Glu Ala 
                85                  90                  95      


Val Thr Phe Lys Ala Val Arg Gln Gly Gly Arg Leu Asn Lys Asp Leu 
            100                 105                 110         


Arg His Phe Leu Asn Gln Arg Phe Gln Lys Gly Ser Pro Asp His Glu 
        115                 120                 125             


Leu Gln Gln Thr Ile Arg Asp Asn Leu Tyr Arg His Ala Val Pro Cys 
    130                 135                 140                 


Thr Thr Arg Ser Pro Arg Glu Gly Glu Val Pro Gly Val Asp Tyr Asn 
145                 150                 155                 160 


Phe Leu Thr Val Lys Glu Phe Leu Asp Leu Glu Gln Ser Gly Thr Leu 
                165                 170                 175     


Leu Glu Val Gly Thr Tyr Glu Gly Asn Tyr Tyr Gly Thr Pro Lys Pro 
            180                 185                 190         


Pro Ser Gln Pro Val Ser Gly Lys Val Ile Thr Thr Asp Ala Leu His 
        195                 200                 205             


Ser Leu Gln Ser Gly Ser Lys Gln Ser Thr Pro Lys Arg Thr Lys Ser 
    210                 215                 220                 


Tyr Asn Asp Met Gln Asn Ala Gly Ile Val His Ala Glu Asn Glu Glu 
225                 230                 235                 240 


Glu Asp Asp Val Pro Glu Met Asn Ser Ser Phe Thr Ala Asp Ser Gly 
                245                 250                 255     


Glu Gln Glu Glu His Thr Leu Gln Glu Thr Ala Leu Pro Pro Val Asn 
            260                 265                 270         


Ser Ser Ile Ile Ala Ala Pro Ile Thr Asp Pro Ser Gln Lys Phe Pro 
        275                 280                 285             


Gln Tyr Leu Pro Leu Ser Ala Glu Asp Asn Leu Gly Pro Leu Pro Glu 
    290                 295                 300                 


Asn Trp Glu Met Ala Tyr Thr Glu Asn Gly Glu Val Tyr Phe Ile Asp 
305                 310                 315                 320 


His Asn Thr Lys Thr Thr Ser Trp Leu Asp Pro Arg Cys Leu Asn Lys 
                325                 330                 335     


Gln Gln Lys Pro Leu Glu Glu Cys Glu Asp Asp Glu Gly Val His Thr 
            340                 345                 350         


Glu Glu Leu Asp Ser Glu Leu Glu Leu Pro Ala Gly Trp Glu Lys Ile 
        355                 360                 365             


Glu Asp Pro Val Tyr Gly Ile Tyr Tyr Val Asp His Ile Asn Arg Lys 
    370                 375                 380                 


Thr Gln Tyr Glu Asn Pro Val Leu Glu Ala Lys Arg Lys Lys Gln Leu 
385                 390                 395                 400 


Glu Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln 
                405                 410                 415     


Gln Gln Gln Gln Gln Thr Glu Glu Trp Thr Glu Asp His Ser Ala Leu 
            420                 425                 430         


Val Pro Pro Val Ile Pro Asn His Pro Pro Ser Asn Pro Glu Pro Ala 
        435                 440                 445             


Arg Glu Val Pro Leu Gln Gly Lys Pro Phe Phe Thr Arg Asn Pro Ser 
    450                 455                 460                 


Glu Leu Lys Gly Lys Phe Ile His Thr Lys Leu Arg Lys Ser Ser Arg 
465                 470                 475                 480 


Gly Phe Gly Phe Thr Val Val Gly Gly Asp Glu Pro Asp Glu Phe Leu 
                485                 490                 495     


Gln Ile Lys Ser Leu Val Leu Asp Gly Pro Ala Ala Leu Asp Gly Lys 
            500                 505                 510         


Met Glu Thr Gly Asp Val Ile Val Ser Val Asn Asp Thr Cys Val Leu 
        515                 520                 525             


Gly His Thr His Ala Gln Val Val Lys Ile Phe Gln Ser Ile Pro Ile 
    530                 535                 540                 


Gly Ala Ser Val Asp Leu Glu Leu Cys Arg Gly Tyr Pro Leu Pro Phe 
545                 550                 555                 560 


Asp Pro Asp Asp Pro Asn Thr Ser Leu Val Thr Ser Val Ala Ile Leu 
                565                 570                 575     


Asp Lys Glu Pro Ile Ile Val Asn Gly Gln Glu Thr Tyr Asp Ser Pro 
            580                 585                 590         


Ala Ser His Ser Ser Lys Thr Gly Lys Val Asn Gly Met Lys Asp Ala 
        595                 600                 605             


Arg Pro Ser Ser Pro Ala Asp Val Ala Ser Asn Ser Ser His Gly Tyr 
    610                 615                 620                 


Pro Asn Asp Thr Val Ser Leu Ala Ser Ser Ile Ala Thr Gln Pro Glu 
625                 630                 635                 640 


Leu Ile Thr Val His Ile Val Lys Gly Pro Met Gly Phe Gly Phe Thr 
                645                 650                 655     


Ile Ala Asp Ser Pro Gly Gly Gly Gly Gln Arg Val Lys Gln Ile Val 
            660                 665                 670         


Asp Ser Pro Arg Cys Arg Gly Leu Lys Glu Gly Asp Leu Ile Val Glu 
        675                 680                 685             


Val Asn Lys Lys Asn Val Gln Ala Leu Thr His Asn Gln Val Val Asp 
    690                 695                 700                 


Met Leu Val Glu Cys Pro Lys Gly Ser Glu Val Thr Leu Leu Val Gln 
705                 710                 715                 720 


Arg Gly Gly Leu Pro Val Pro Lys Lys Ser Pro Lys Ser Gln Pro Leu 
                725                 730                 735     


Glu Arg Lys Asp Ser Gln Asn Ser Ser Gln His Ser Val Ser Ser His 
            740                 745                 750         


Arg Ser Leu His Thr Ala Ser Pro Ser His Ser Thr Gln Val Leu Pro 
        755                 760                 765             


Glu Phe Pro Pro Ala Glu Ala Gln Ala Pro Asp Gln Thr Asp Ser Ser 
    770                 775                 780                 


Gly Gln Lys Lys Pro Asp Pro Phe Lys Ile Trp Ala Gln Ser Arg Ser 
785                 790                 795                 800 


Met Tyr Glu Asn Arg Leu Pro Asp Tyr Gln Glu Gln Asp Ile Phe Leu 
                805                 810                 815     


Trp Arg Lys Glu Thr Gly Phe Gly Phe Arg Ile Leu Gly Gly Asn Glu 
            820                 825                 830         


Pro Gly Glu Pro Ile Tyr Ile Gly His Ile Val Pro Leu Gly Ala Ala 
        835                 840                 845             


Asp Thr Asp Gly Arg Leu Arg Ser Gly Asp Glu Leu Ile Cys Val Asp 
    850                 855                 860                 


Gly Thr Pro Val Ile Gly Lys Ser His Gln Leu Val Val Gln Leu Met 
865                 870                 875                 880 


Gln Gln Ala Ala Lys Gln Gly His Val Asn Leu Thr Val Arg Arg Lys 
                885                 890                 895     


Val Val Phe Ala Val Pro Lys Thr Glu Asn Glu Val Pro Ser Pro Ala 
            900                 905                 910         


Ser Ser His His Ser Ser Asn Gln Pro Ala Ser Leu Thr Glu Glu Lys 
        915                 920                 925             


Arg Thr Pro Gln Gly Ser Gln Asn Ser Leu Asn Thr Val Ser Ser Gly 
    930                 935                 940                 


Ser Gly Ser Thr Ser Gly Ile Gly Ser Gly Gly Gly Gly Gly Ser Gly 
945                 950                 955                 960 


Val Val Ser Thr Val Val Gln Pro Tyr Asp Val Glu Ile Arg Arg Gly 
                965                 970                 975     


Glu Asn Glu Gly Phe Gly Phe Val Ile Val Ser Ser Val Ser Arg Pro 
            980                 985                 990         


Glu Ala Gly Thr Thr Phe Gly Asn  Ala Cys Val Ala Met  Pro His Lys 
        995                 1000                 1005             


Ile Gly  Arg Ile Ile Glu Gly  Ser Pro Ala Asp Arg  Cys Gly Lys 
    1010                 1015                 1020             


Leu Lys  Val Gly Asp Arg Ile  Leu Ala Val Asn Gly  Cys Ser Ile 
    1025                 1030                 1035             


Thr Asn  Lys Ser His Ser Asp  Ile Val Asn Leu Ile  Lys Glu Ala 
    1040                 1045                 1050             


Gly Asn  Thr Val Thr Leu Arg  Ile Ile Pro Gly Asp  Glu Ser Ser 
    1055                 1060                 1065             


Asn Ala  Thr Leu Leu Thr Asn  Ala Glu Lys Ile Ala  Thr Ile Thr 
    1070                 1075                 1080             


Thr Thr  His Thr Pro Ser Gln  Gln Gly Thr Gln Glu  Thr Arg Asn 
    1085                 1090                 1095             


Thr Thr  Lys Pro Lys Gln Glu  Ser Gln Phe Glu Phe  Lys Ala Pro 
    1100                 1105                 1110             


Gln Ala  Thr Gln Glu Gln Asp  Phe Tyr Thr Val Glu  Leu Glu Arg 
    1115                 1120                 1125             


Gly Ala  Lys Gly Phe Gly Phe  Ser Leu Arg Gly Gly  Arg Glu Tyr 
    1130                 1135                 1140             


Asn Met  Asp Leu Tyr Val Leu  Arg Leu Ala Glu Asp  Gly Pro Ala 
    1145                 1150                 1155             


Glu Arg  Cys Gly Lys Met Arg  Ile Gly Asp Glu Ile  Leu Glu Ile 
    1160                 1165                 1170             


Asn Gly  Glu Thr Thr Lys Asn  Met Lys His Ser Arg  Ala Ile Glu 
    1175                 1180                 1185             


Leu Ile  Lys Asn Gly Gly Arg  Arg Val Arg Leu Phe  Leu Lys Arg 
    1190                 1195                 1200             


Gly Asp  Gly Ser Val Pro Glu  Tyr Asp Pro Ser Ser  Asp Arg His 
    1205                 1210                 1215             


Gly Pro  Ala Thr Gly Pro Gln  Gly Val Pro Glu Val  Arg Ala Gly 
    1220                 1225                 1230             


Pro Asp  Arg Arg Gln His Pro  Ser Leu Glu Ser Ser  Tyr Pro Pro 
    1235                 1240                 1245             


Asp Leu  His Lys Ser Ser Pro  His Gly Glu Lys Arg  Ala His Ala 
    1250                 1255                 1260             


Arg Asp  Pro Lys Gly Ser Arg  Glu Tyr Ser Arg Gln  Pro Asn Glu 
    1265                 1270                 1275             


His His  Thr Trp Asn Gly Thr  Ser Arg Lys Pro Asp  Ser Gly Ala 
    1280                 1285                 1290             


Cys Arg  Pro Lys Asp Arg Ala  Pro Glu Gly Arg Arg  Asp Ala Gln 
    1295                 1300                 1305             


Ala Glu  Arg Ala Ala Ala Ala  Asn Gly Pro Lys Arg  Arg Ser Pro 
    1310                 1315                 1320             


Glu Lys  Arg Arg Glu Gly Thr  Arg Ser Ala Asp Asn  Thr Leu Glu 
    1325                 1330                 1335             


Arg Arg  Glu Lys His Glu Lys  Arg Arg Asp Val Ser  Pro Glu Arg 
    1340                 1345                 1350             


Arg Arg  Glu Arg Ser Pro Thr  Arg Arg Arg Asp Gly  Ser Pro Ser 
    1355                 1360                 1365             


Arg Arg  Arg Arg Ser Leu Glu  Arg Leu Leu Glu Gln  Arg Arg Ser 
    1370                 1375                 1380             


Pro Glu  Arg Arg Arg Gly Gly  Ser Pro Glu Arg Arg  Ala Lys Ser 
    1385                 1390                 1395             


Thr Asp  Arg Arg Arg Ala Arg  Ser Pro Glu Arg Arg  Arg Glu Arg 
    1400                 1405                 1410             


Ser Leu  Asp Lys Arg Asn Arg  Glu Asp Arg Ala Ser  His Arg Glu 
    1415                 1420                 1425             


Arg Glu  Glu Ala Asn Leu Lys  Gln Asp Ala Gly Arg  Ser Ser Arg 
    1430                 1435                 1440             


His Pro  Pro Glu Gln Arg Arg  Arg Pro Tyr Lys Glu  Cys Ser Thr 
    1445                 1450                 1455             


Asp Leu  Ser Ile 
    1460         


<210>  1551
<211>  218
<212>  PRT
<213>  Homo sapiens

<400>  1551

Met Gly Thr Arg Asp Asp Glu Tyr Asp Tyr Leu Phe Lys Val Val Leu 
1               5                   10                  15      


Ile Gly Asp Ser Gly Val Gly Lys Ser Asn Leu Leu Ser Arg Phe Thr 
            20                  25                  30          


Arg Asn Glu Phe Asn Leu Glu Ser Lys Ser Thr Ile Gly Val Glu Phe 
        35                  40                  45              


Ala Thr Arg Ser Ile Gln Val Asp Gly Lys Thr Ile Lys Ala Gln Ile 
    50                  55                  60                  


Trp Asp Thr Ala Gly Gln Glu Arg Tyr Arg Ala Ile Thr Ser Ala Tyr 
65                  70                  75                  80  


Tyr Arg Gly Ala Val Gly Ala Leu Leu Val Tyr Asp Ile Ala Lys His 
                85                  90                  95      


Leu Thr Tyr Glu Asn Val Glu Arg Trp Leu Lys Glu Leu Arg Asp His 
            100                 105                 110         


Ala Asp Ser Asn Ile Val Ile Met Leu Val Gly Asn Lys Ser Asp Leu 
        115                 120                 125             


Arg His Leu Arg Ala Val Pro Thr Asp Glu Ala Arg Ala Phe Ala Glu 
    130                 135                 140                 


Lys Asn Asn Leu Ser Phe Ile Glu Thr Ser Ala Leu Asp Ser Thr Asn 
145                 150                 155                 160 


Val Glu Glu Ala Phe Lys Asn Ile Leu Thr Glu Ile Tyr Arg Ile Val 
                165                 170                 175     


Ser Gln Lys Gln Ile Ala Asp Arg Ala Ala His Asp Glu Ser Pro Gly 
            180                 185                 190         


Asn Asn Val Val Asp Ile Ser Val Pro Pro Thr Thr Asp Gly Gln Lys 
        195                 200                 205             


Pro Asn Lys Leu Gln Cys Cys Gln Asn Leu 
    210                 215             


<210>  1552
<211>  309
<212>  PRT
<213>  Homo sapiens

<400>  1552

Met Asp Ala Leu Thr Ala Asn Gly Thr Thr Asn Ile Gln Thr Ser Val 
1               5                   10                  15      


Thr Gly Val Thr Ala Ser Lys Arg Lys Phe Ile Asp Asp Arg Arg Asp 
            20                  25                  30          


Gln Pro Phe Asp Lys Arg Leu Arg Phe Ser Val Arg Gln Thr Glu Ser 
        35                  40                  45              


Ala Tyr Arg Tyr Arg Asp Ile Val Val Arg Lys Gln Asp Gly Phe Thr 
    50                  55                  60                  


His Ile Leu Leu Ser Thr Lys Ser Ser Glu Asn Asn Ser Leu Asn Pro 
65                  70                  75                  80  


Glu Val Met Arg Glu Val Gln Ser Ala Leu Ser Thr Ala Ala Ala Asp 
                85                  90                  95      


Asp Ser Lys Leu Val Leu Leu Ser Ala Val Gly Ser Val Phe Cys Cys 
            100                 105                 110         


Gly Leu Asp Phe Ile Tyr Phe Ile Arg Arg Leu Thr Asp Asp Arg Lys 
        115                 120                 125             


Arg Glu Ser Thr Lys Met Ala Glu Ala Ile Arg Asn Phe Val Asn Thr 
    130                 135                 140                 


Phe Ile Gln Phe Lys Lys Pro Ile Ile Val Ala Val Asn Gly Pro Ala 
145                 150                 155                 160 


Ile Gly Leu Gly Ala Ser Ile Leu Pro Leu Cys Asp Val Val Trp Ala 
                165                 170                 175     


Asn Glu Lys Ala Trp Phe Gln Thr Pro Tyr Thr Thr Phe Gly Gln Ser 
            180                 185                 190         


Pro Asp Gly Cys Ser Thr Val Met Phe Pro Lys Ile Met Gly Gly Ala 
        195                 200                 205             


Ser Ala Asn Glu Met Leu Leu Ser Gly Arg Lys Leu Thr Ala Gln Glu 
    210                 215                 220                 


Ala Cys Gly Lys Gly Leu Val Ser Gln Val Phe Trp Pro Gly Thr Phe 
225                 230                 235                 240 


Thr Gln Glu Val Met Val Arg Ile Lys Glu Leu Ala Ser Cys Asn Pro 
                245                 250                 255     


Val Val Leu Glu Glu Ser Lys Ala Leu Val Arg Cys Asn Met Lys Met 
            260                 265                 270         


Glu Leu Glu Gln Ala Asn Glu Arg Glu Cys Glu Val Leu Lys Lys Ile 
        275                 280                 285             


Trp Gly Ser Ala Gln Gly Thr Asp Ser Met Leu Lys Tyr Met Gln Arg 
    290                 295                 300                 


Lys Ile Asp Glu Phe 
305                 


<210>  1553
<211>  297
<212>  PRT
<213>  Homo sapiens

<400>  1553

Met Ala Lys Val Ser Glu Leu Tyr Asp Val Thr Trp Glu Glu Met Arg 
1               5                   10                  15      


Asp Lys Met Arg Lys Trp Arg Glu Glu Asn Ser Arg Asn Ser Glu Gln 
            20                  25                  30          


Ile Val Glu Val Gly Glu Glu Leu Ile Asn Glu Tyr Ala Ser Lys Leu 
        35                  40                  45              


Gly Asp Asp Ile Trp Ile Ile Tyr Glu Gln Val Met Ile Ala Ala Leu 
    50                  55                  60                  


Asp Tyr Gly Arg Asp Asp Leu Ala Leu Phe Cys Leu Gln Glu Leu Arg 
65                  70                  75                  80  


Arg Gln Phe Pro Gly Ser His Arg Val Lys Arg Leu Thr Gly Met Arg 
                85                  90                  95      


Phe Glu Ala Met Glu Arg Tyr Asp Asp Ala Ile Gln Leu Tyr Asp Arg 
            100                 105                 110         


Ile Leu Gln Glu Asp Pro Thr Asn Thr Ala Ala Arg Lys Arg Lys Ile 
        115                 120                 125             


Ala Ile Arg Lys Ala Gln Gly Lys Asn Val Glu Ala Ile Arg Glu Leu 
    130                 135                 140                 


Asn Glu Tyr Leu Glu Gln Phe Val Gly Asp Gln Glu Ala Trp His Glu 
145                 150                 155                 160 


Leu Ala Glu Leu Tyr Ile Asn Glu His Asp Tyr Ala Lys Ala Ala Phe 
                165                 170                 175     


Cys Leu Glu Glu Leu Met Met Thr Asn Pro His Asn His Leu Tyr Cys 
            180                 185                 190         


Gln Gln Tyr Ala Glu Val Lys Tyr Thr Gln Gly Gly Leu Glu Asn Leu 
        195                 200                 205             


Glu Leu Ser Arg Lys Tyr Phe Ala Gln Ala Leu Lys Leu Asn Asn Arg 
    210                 215                 220                 


Asn Met Arg Ala Leu Phe Gly Leu Tyr Met Ser Ala Ser His Ile Ala 
225                 230                 235                 240 


Ser Asn Pro Lys Ala Ser Ala Lys Thr Lys Lys Asp Asn Met Lys Tyr 
                245                 250                 255     


Ala Ser Trp Ala Ala Ser Gln Ile Asn Arg Ala Tyr Gln Phe Ala Gly 
            260                 265                 270         


Arg Ser Lys Lys Glu Thr Lys Tyr Ser Leu Lys Ala Val Glu Asp Met 
        275                 280                 285             


Leu Glu Thr Leu Gln Ile Thr Gln Ser 
    290                 295         


<210>  1554
<211>  4374
<212>  PRT
<213>  Homo sapiens

<400>  1554

Met Lys Val Asp Arg Thr Lys Leu Lys Lys Thr Pro Thr Glu Ala Pro 
1               5                   10                  15      


Ala Asp Cys Arg Ala Leu Ile Asp Lys Leu Lys Val Cys Asn Asp Glu 
            20                  25                  30          


Gln Leu Leu Leu Glu Leu Gln Gln Ile Lys Thr Trp Asn Ile Gly Lys 
        35                  40                  45              


Cys Glu Leu Tyr His Trp Val Asp Leu Leu Asp Arg Phe Asp Gly Ile 
    50                  55                  60                  


Leu Ala Asp Ala Gly Gln Thr Val Glu Asn Met Ser Trp Met Leu Val 
65                  70                  75                  80  


Cys Asp Arg Pro Glu Arg Glu Gln Leu Lys Met Leu Leu Leu Ala Val 
                85                  90                  95      


Leu Asn Phe Thr Ala Leu Leu Ile Glu Tyr Ser Phe Ser Arg His Leu 
            100                 105                 110         


Tyr Ser Ser Ile Glu His Leu Thr Thr Leu Leu Ala Ser Ser Asp Met 
        115                 120                 125             


Gln Val Val Leu Ala Val Leu Asn Leu Leu Tyr Val Phe Ser Lys Arg 
    130                 135                 140                 


Ser Asn Tyr Ile Thr Arg Leu Gly Ser Asp Lys Arg Thr Pro Leu Leu 
145                 150                 155                 160 


Thr Arg Leu Gln His Leu Ala Glu Ser Trp Gly Gly Lys Glu Asn Gly 
                165                 170                 175     


Phe Gly Leu Ala Glu Cys Cys Arg Asp Leu His Met Met Lys Tyr Pro 
            180                 185                 190         


Pro Ser Ala Thr Thr Leu His Phe Glu Phe Tyr Ala Asp Pro Gly Ala 
        195                 200                 205             


Glu Val Lys Ile Glu Lys Arg Thr Thr Ser Asn Thr Leu His Tyr Ile 
    210                 215                 220                 


His Ile Glu Gln Leu Asp Lys Ile Ser Glu Ser Pro Ser Glu Ile Met 
225                 230                 235                 240 


Glu Ser Leu Thr Lys Met Tyr Ser Ile Pro Lys Asp Lys Gln Met Leu 
                245                 250                 255     


Leu Phe Thr His Ile Arg Leu Ala His Gly Phe Ser Asn His Arg Lys 
            260                 265                 270         


Arg Leu Gln Ala Val Gln Ala Arg Leu His Ala Ile Ser Ile Leu Val 
        275                 280                 285             


Tyr Ser Asn Ala Leu Gln Glu Ser Ala Asn Ser Ile Leu Tyr Asn Gly 
    290                 295                 300                 


Leu Ile Glu Glu Leu Val Asp Val Leu Gln Ile Thr Asp Lys Gln Leu 
305                 310                 315                 320 


Met Glu Ile Lys Ala Ala Ser Leu Arg Thr Leu Thr Ser Ile Val His 
                325                 330                 335     


Leu Glu Arg Thr Pro Lys Leu Ser Ser Ile Ile Asp Cys Thr Gly Thr 
            340                 345                 350         


Ala Ser Tyr His Gly Phe Leu Pro Val Leu Val Arg Asn Cys Ile Gln 
        355                 360                 365             


Ala Met Ile Asp Pro Ser Met Asp Pro Tyr Pro His Gln Phe Ala Thr 
    370                 375                 380                 


Ala Leu Phe Ser Phe Leu Tyr His Leu Ala Ser Tyr Asp Ala Gly Gly 
385                 390                 395                 400 


Glu Ala Leu Val Ser Cys Gly Met Met Glu Ala Leu Leu Lys Val Ile 
                405                 410                 415     


Lys Phe Leu Gly Asp Glu Gln Asp Gln Ile Thr Phe Val Thr Arg Ala 
            420                 425                 430         


Val Arg Val Val Asp Leu Ile Thr Asn Leu Asp Met Ala Ala Phe Gln 
        435                 440                 445             


Ser His Ser Gly Leu Ser Ile Phe Ile Tyr Arg Leu Glu His Glu Val 
    450                 455                 460                 


Asp Leu Cys Arg Lys Glu Cys Pro Phe Val Ile Lys Pro Lys Ile Gln 
465                 470                 475                 480 


Arg Pro Asn Thr Thr Gln Glu Gly Glu Glu Met Glu Thr Asp Met Asp 
                485                 490                 495     


Gly Val Gln Cys Ile Pro Gln Arg Ala Ala Leu Leu Lys Ser Met Leu 
            500                 505                 510         


Asn Phe Leu Lys Lys Ala Ile Gln Asp Pro Ala Phe Ser Asp Gly Ile 
        515                 520                 525             


Arg His Val Met Asp Gly Ser Leu Pro Thr Ser Leu Lys His Ile Ile 
    530                 535                 540                 


Ser Asn Ala Glu Tyr Tyr Gly Pro Ser Leu Phe Leu Leu Ala Thr Glu 
545                 550                 555                 560 


Val Val Thr Val Phe Val Phe Gln Glu Pro Ser Leu Leu Ser Ser Leu 
                565                 570                 575     


Gln Asp Asn Gly Leu Thr Asp Val Met Leu His Ala Leu Leu Ile Lys 
            580                 585                 590         


Asp Val Pro Ala Thr Arg Glu Val Leu Gly Ser Leu Pro Asn Val Phe 
        595                 600                 605             


Ser Ala Leu Cys Leu Asn Ala Arg Gly Leu Gln Ser Phe Val Gln Cys 
    610                 615                 620                 


Gln Pro Phe Glu Arg Leu Phe Lys Val Leu Leu Ser Pro Asp Tyr Leu 
625                 630                 635                 640 


Pro Ala Met Arg Arg Arg Arg Ser Ser Asp Pro Leu Gly Asp Thr Ala 
                645                 650                 655     


Ser Asn Leu Gly Ser Ala Val Asp Glu Leu Met Arg His Gln Pro Thr 
            660                 665                 670         


Leu Lys Thr Asp Ala Thr Thr Ala Ile Ile Lys Leu Leu Glu Glu Ile 
        675                 680                 685             


Cys Asn Leu Gly Arg Asp Pro Lys Tyr Ile Cys Gln Lys Pro Ser Ile 
    690                 695                 700                 


Gln Lys Ala Asp Gly Thr Ala Thr Ala Pro Pro Pro Arg Ser Asn His 
705                 710                 715                 720 


Ala Ala Glu Glu Ala Ser Ser Glu Asp Glu Glu Glu Glu Glu Val Gln 
                725                 730                 735     


Ala Met Gln Ser Phe Asn Ser Thr Gln Gln Asn Glu Thr Glu Pro Asn 
            740                 745                 750         


Gln Gln Val Val Gly Thr Glu Glu Arg Ile Pro Ile Pro Leu Met Asp 
        755                 760                 765             


Tyr Ile Leu Asn Val Met Lys Phe Val Glu Ser Ile Leu Ser Asn Asn 
    770                 775                 780                 


Thr Thr Asp Asp His Cys Gln Glu Phe Val Asn Gln Lys Gly Leu Leu 
785                 790                 795                 800 


Pro Leu Val Thr Ile Leu Gly Leu Pro Asn Leu Pro Ile Asp Phe Pro 
                805                 810                 815     


Thr Ser Ala Ala Cys Gln Ala Val Ala Gly Val Cys Lys Ser Ile Leu 
            820                 825                 830         


Thr Leu Ser His Glu Pro Lys Val Leu Gln Glu Gly Leu Leu Gln Leu 
        835                 840                 845             


Asp Ser Ile Leu Ser Ser Leu Glu Pro Leu His Arg Pro Ile Glu Ser 
    850                 855                 860                 


Pro Gly Gly Ser Val Leu Leu Arg Glu Leu Ala Cys Ala Gly Asn Val 
865                 870                 875                 880 


Ala Asp Ala Thr Leu Ser Ala Gln Ala Thr Pro Leu Leu His Ala Leu 
                885                 890                 895     


Thr Ala Ala His Ala Tyr Ile Met Met Phe Val His Thr Cys Arg Val 
            900                 905                 910         


Gly Gln Ser Glu Ile Arg Ser Ile Ser Val Asn Gln Trp Gly Ser Gln 
        915                 920                 925             


Leu Gly Leu Ser Val Leu Ser Lys Leu Ser Gln Leu Tyr Cys Ser Leu 
    930                 935                 940                 


Val Trp Glu Ser Thr Val Leu Leu Ser Leu Cys Thr Pro Asn Ser Leu 
945                 950                 955                 960 


Pro Ser Gly Cys Glu Phe Gly Gln Ala Asp Met Gln Lys Leu Val Pro 
                965                 970                 975     


Lys Asp Glu Lys Ala Gly Thr Thr Gln Gly Gly Lys Arg Ser Asp Gly 
            980                 985                 990         


Glu Gln Asp Gly Ala Ala Gly Ser  Met Asp Ala Ser Thr  Gln Gly Leu 
        995                 1000                 1005             


Leu Glu  Gly Ile Gly Leu Asp  Gly Asp Thr Leu Ala  Pro Met Glu 
    1010                 1015                 1020             


Thr Asp  Glu Pro Thr Ala Ser  Asp Ser Lys Gly Lys  Ser Lys Ile 
    1025                 1030                 1035             


Thr Pro  Ala Met Ala Ala Arg  Ile Lys Gln Ile Lys  Pro Leu Leu 
    1040                 1045                 1050             


Ser Ala  Ser Ser Arg Leu Gly  Arg Ala Leu Ala Glu  Leu Phe Gly 
    1055                 1060                 1065             


Leu Leu  Val Lys Leu Cys Val  Gly Ser Pro Val Arg  Gln Arg Arg 
    1070                 1075                 1080             


Ser His  His Ala Ala Ser Thr  Thr Thr Ala Pro Thr  Pro Ala Ala 
    1085                 1090                 1095             


Arg Ser  Thr Ala Ser Ala Leu  Thr Lys Leu Leu Thr  Lys Gly Leu 
    1100                 1105                 1110             


Ser Trp  Gln Pro Pro Pro Tyr  Thr Pro Thr Pro Arg  Phe Arg Leu 
    1115                 1120                 1125             


Thr Phe  Phe Ile Cys Ser Val  Gly Phe Thr Ser Pro  Met Leu Phe 
    1130                 1135                 1140             


Asp Glu  Arg Lys Tyr Pro Tyr  His Leu Met Leu Gln  Lys Phe Leu 
    1145                 1150                 1155             


Cys Ser  Gly Gly His Asn Ala  Leu Phe Glu Thr Phe  Asn Trp Ala 
    1160                 1165                 1170             


Leu Ser  Met Gly Gly Lys Val  Pro Val Ser Glu Gly  Leu Glu His 
    1175                 1180                 1185             


Ser Asp  Leu Pro Asp Gly Thr  Gly Glu Phe Leu Asp  Ala Trp Leu 
    1190                 1195                 1200             


Met Leu  Val Glu Lys Met Val  Asn Pro Thr Thr Val  Leu Glu Ser 
    1205                 1210                 1215             


Pro His  Ser Leu Pro Ala Lys  Leu Pro Gly Gly Val  Gln Asn Phe 
    1220                 1225                 1230             


Pro Gln  Phe Ser Ala Leu Arg  Phe Leu Val Val Thr  Gln Lys Ala 
    1235                 1240                 1245             


Ala Phe  Thr Cys Ile Lys Asn  Leu Trp Asn Arg Lys  Pro Leu Lys 
    1250                 1255                 1260             


Val Tyr  Gly Gly Arg Met Ala  Glu Ser Met Leu Ala  Ile Leu Cys 
    1265                 1270                 1275             


His Ile  Leu Arg Gly Glu Pro  Val Ile Arg Glu Arg  Leu Ser Lys 
    1280                 1285                 1290             


Glu Lys  Glu Gly Ser Arg Gly  Glu Glu Asp Thr Gly  Gln Glu Glu 
    1295                 1300                 1305             


Gly Gly  Ser Arg Arg Glu Pro  Gln Val Asn Gln Gln  Gln Leu Gln 
    1310                 1315                 1320             


Gln Leu  Met Asp Met Gly Phe  Thr Arg Glu His Ala  Met Glu Ala 
    1325                 1330                 1335             


Leu Leu  Asn Thr Ser Thr Met  Glu Gln Ala Thr Glu  Tyr Leu Leu 
    1340                 1345                 1350             


Thr His  Pro Pro Pro Ile Met  Gly Gly Val Val Arg  Asp Leu Ser 
    1355                 1360                 1365             


Met Ser  Glu Glu Asp Gln Met  Met Arg Ala Ile Ala  Met Ser Leu 
    1370                 1375                 1380             


Gly Gln  Asp Ile Pro Met Asp  Gln Arg Ala Glu Ser  Pro Glu Glu 
    1385                 1390                 1395             


Val Ala  Cys Arg Lys Glu Glu  Glu Glu Arg Lys Ala  Arg Glu Lys 
    1400                 1405                 1410             


Gln Glu  Glu Glu Glu Ala Lys  Cys Leu Glu Lys Phe  Gln Asp Ala 
    1415                 1420                 1425             


Asp Pro  Leu Glu Gln Asp Glu  Leu His Thr Phe Thr  Asp Thr Met 
    1430                 1435                 1440             


Leu Pro  Gly Cys Phe His Leu  Leu Asp Glu Leu Pro  Asp Thr Val 
    1445                 1450                 1455             


Tyr Arg  Val Cys Asp Leu Ile  Met Thr Ala Ile Lys  Arg Asn Gly 
    1460                 1465                 1470             


Ala Asp  Tyr Arg Asp Met Ile  Leu Lys Gln Val Val  Asn Gln Val 
    1475                 1480                 1485             


Trp Glu  Ala Ala Asp Val Leu  Ile Lys Ala Ala Leu  Pro Leu Thr 
    1490                 1495                 1500             


Thr Ser  Asp Thr Lys Thr Val  Ser Glu Trp Ile Ser  Gln Met Ala 
    1505                 1510                 1515             


Thr Leu  Pro Gln Ala Ser Asn  Leu Ala Thr Arg Ile  Leu Leu Leu 
    1520                 1525                 1530             


Thr Leu  Leu Phe Glu Glu Leu  Lys Leu Pro Cys Ala  Trp Val Val 
    1535                 1540                 1545             


Glu Ser  Ser Gly Ile Leu Asn  Val Leu Ile Lys Leu  Leu Glu Val 
    1550                 1555                 1560             


Val Gln  Pro Cys Leu Gln Ala  Ala Lys Glu Gln Lys  Glu Val Gln 
    1565                 1570                 1575             


Thr Pro  Lys Trp Ile Thr Pro  Val Leu Leu Leu Ile  Asp Phe Tyr 
    1580                 1585                 1590             


Glu Lys  Thr Ala Ile Ser Ser  Lys Arg Arg Ala Gln  Met Thr Lys 
    1595                 1600                 1605             


Tyr Leu  Gln Ser Asn Ser Asn  Asn Trp Arg Trp Phe  Asp Asp Arg 
    1610                 1615                 1620             


Ser Gly  Arg Trp Cys Ser Tyr  Ser Ala Ser Asn Asn  Ser Thr Ile 
    1625                 1630                 1635             


Asp Ser  Ala Trp Lys Ser Gly  Glu Thr Ser Val Arg  Phe Thr Ala 
    1640                 1645                 1650             


Gly Arg  Arg Arg Tyr Thr Val  Gln Phe Thr Thr Met  Val Gln Val 
    1655                 1660                 1665             


Asn Glu  Glu Thr Gly Asn Arg  Arg Pro Val Met Leu  Thr Leu Leu 
    1670                 1675                 1680             


Arg Val  Pro Arg Leu Asn Lys  Asn Ser Lys Asn Ser  Asn Gly Gln 
    1685                 1690                 1695             


Glu Leu  Glu Lys Thr Leu Glu  Glu Ser Lys Glu Met  Asp Ile Lys 
    1700                 1705                 1710             


Arg Lys  Glu Asn Lys Gly Asn  Asp Thr Pro Leu Ala  Leu Glu Ser 
    1715                 1720                 1725             


Thr Asn  Thr Glu Lys Glu Thr  Ser Leu Glu Glu Thr  Lys Ile Gly 
    1730                 1735                 1740             


Glu Ile  Leu Ile Gln Gly Leu  Thr Glu Asp Met Val  Thr Val Leu 
    1745                 1750                 1755             


Ile Arg  Ala Cys Val Ser Met  Leu Gly Val Pro Val  Asp Pro Asp 
    1760                 1765                 1770             


Thr Leu  His Ala Thr Leu Arg  Leu Cys Leu Arg Leu  Thr Arg Asp 
    1775                 1780                 1785             


His Lys  Tyr Ala Met Met Phe  Ala Glu Leu Lys Ser  Thr Arg Met 
    1790                 1795                 1800             


Ile Leu  Asn Leu Thr Gln Ser  Ser Gly Phe Asn Gly  Phe Thr Pro 
    1805                 1810                 1815             


Leu Val  Thr Leu Leu Leu Arg  His Ile Ile Glu Asp  Pro Cys Thr 
    1820                 1825                 1830             


Leu Arg  His Thr Met Glu Lys  Val Val Arg Ser Ala  Ala Thr Ser 
    1835                 1840                 1845             


Gly Ala  Gly Ser Thr Thr Ser  Gly Val Val Ser Gly  Ser Leu Gly 
    1850                 1855                 1860             


Ser Arg  Glu Ile Asn Tyr Ile  Leu Arg Val Leu Gly  Pro Ala Ala 
    1865                 1870                 1875             


Cys Arg  Asn Pro Asp Ile Phe  Thr Glu Val Ala Asn  Cys Cys Ile 
    1880                 1885                 1890             


Arg Ile  Ala Leu Pro Ala Pro  Arg Gly Ser Gly Thr  Ala Ser Asp 
    1895                 1900                 1905             


Asp Glu  Phe Glu Asn Leu Arg  Ile Lys Gly Pro Asn  Ala Val Gln 
    1910                 1915                 1920             


Leu Val  Lys Thr Thr Pro Leu  Lys Pro Ser Pro Leu  Pro Val Ile 
    1925                 1930                 1935             


Pro Asp  Thr Ile Lys Glu Val  Ile Tyr Asp Met Leu  Asn Ala Leu 
    1940                 1945                 1950             


Ala Ala  Tyr His Ala Pro Glu  Glu Ala Asp Lys Ser  Asp Pro Lys 
    1955                 1960                 1965             


Pro Gly  Val Met Thr Gln Glu  Val Gly Gln Leu Leu  Gln Asp Met 
    1970                 1975                 1980             


Gly Asp  Asp Val Tyr Gln Gln  Tyr Arg Ser Leu Thr  Arg Gln Ser 
    1985                 1990                 1995             


Ser Asp  Phe Asp Thr Gln Ser  Gly Phe Ser Ile Asn  Ser Gln Val 
    2000                 2005                 2010             


Phe Ala  Ala Asp Gly Ala Ser  Thr Glu Thr Ser Ala  Ser Gly Thr 
    2015                 2020                 2025             


Ser Gln  Gly Glu Ala Ser Thr  Pro Glu Glu Ser Arg  Asp Gly Lys 
    2030                 2035                 2040             


Lys Asp  Lys Glu Gly Asp Arg  Ala Ser Glu Glu Gly  Lys Gln Lys 
    2045                 2050                 2055             


Gly Lys  Gly Ser Lys Pro Leu  Met Pro Thr Ser Thr  Ile Leu Arg 
    2060                 2065                 2070             


Leu Leu  Ala Glu Leu Val Arg  Ser Tyr Val Gly Ile  Ala Thr Leu 
    2075                 2080                 2085             


Ile Ala  Asn Tyr Ser Tyr Thr  Val Gly Gln Ser Glu  Leu Ile Lys 
    2090                 2095                 2100             


Glu Asp  Cys Ser Val Leu Ala  Phe Val Leu Asp His  Leu Leu Pro 
    2105                 2110                 2115             


His Thr  Gln Asn Ala Glu Asp  Lys Asp Thr Pro Ala  Leu Ala Arg 
    2120                 2125                 2130             


Leu Phe  Leu Ala Ser Leu Ala  Ala Ala Gly Ser Gly  Thr Asp Ala 
    2135                 2140                 2145             


Gln Val  Ala Leu Val Asn Glu  Val Lys Ala Ala Leu  Gly Arg Ala 
    2150                 2155                 2160             


Leu Ala  Met Ala Glu Ser Thr  Glu Lys His Ala Arg  Leu Gln Ala 
    2165                 2170                 2175             


Val Met  Cys Ile Ile Ser Thr  Ile Met Glu Ser Cys  Pro Ser Thr 
    2180                 2185                 2190             


Ser Ser  Phe Tyr Ser Ser Ala  Thr Ala Lys Thr Gln  His Asn Gly 
    2195                 2200                 2205             


Met Asn  Asn Ile Ile Arg Leu  Phe Leu Lys Lys Gly  Leu Val Asn 
    2210                 2215                 2220             


Asp Leu  Ala Arg Val Pro His  Ser Leu Asp Leu Ser  Ser Pro Asn 
    2225                 2230                 2235             


Met Ala  Asn Thr Val Asn Ala  Ala Leu Lys Pro Leu  Glu Thr Leu 
    2240                 2245                 2250             


Ser Arg  Ile Val Asn Gln Pro  Ser Ser Leu Phe Gly  Ser Lys Ser 
    2255                 2260                 2265             


Ala Ser  Ser Lys Asn Lys Ser  Glu Gln Asp Ala Gln  Gly Ala Ser 
    2270                 2275                 2280             


Gln Asp  Ser Ser Ser Asn Gln  Gln Asp Pro Gly Glu  Pro Gly Glu 
    2285                 2290                 2295             


Ala Glu  Val Gln Glu Glu Asp  His Asp Val Thr Gln  Thr Glu Val 
    2300                 2305                 2310             


Ala Asp  Gly Asp Ile Met Asp  Gly Glu Ala Glu Thr  Asp Ser Val 
    2315                 2320                 2325             


Val Ile  Ala Gly Gln Pro Glu  Val Leu Ser Ser Gln  Glu Met Gln 
    2330                 2335                 2340             


Val Glu  Asn Glu Leu Glu Asp  Leu Ile Asp Glu Leu  Leu Glu Arg 
    2345                 2350                 2355             


Asp Gly  Gly Ser Gly Asn Ser  Thr Ile Ile Val Ser  Arg Ser Gly 
    2360                 2365                 2370             


Glu Asp  Glu Ser Gln Glu Asp  Val Leu Met Asp Glu  Ala Pro Ser 
    2375                 2380                 2385             


Asn Leu  Ser Gln Ala Ser Thr  Leu Gln Ala Asn Arg  Glu Asp Ser 
    2390                 2395                 2400             


Met Asn  Ile Leu Asp Pro Glu  Asp Glu Glu Glu His  Thr Gln Glu 
    2405                 2410                 2415             


Glu Asp  Ser Ser Gly Ser Asn  Glu Asp Glu Asp Asp  Ser Gln Asp 
    2420                 2425                 2430             


Glu Glu  Glu Glu Glu Glu Glu  Asp Glu Glu Asp Asp  Gln Glu Asp 
    2435                 2440                 2445             


Asp Glu  Gly Glu Glu Gly Asp  Glu Asp Asp Asp Asp  Asp Gly Ser 
    2450                 2455                 2460             


Glu Met  Glu Leu Asp Glu Asp  Tyr Pro Asp Met Asn  Ala Ser Pro 
    2465                 2470                 2475             


Leu Val  Arg Phe Glu Arg Phe  Asp Arg Glu Asp Asp  Leu Ile Ile 
    2480                 2485                 2490             


Glu Phe  Asp Asn Met Phe Ser  Ser Ala Thr Asp Ile  Pro Pro Ser 
    2495                 2500                 2505             


Pro Gly  Asn Ile Pro Thr Thr  His Pro Leu Met Val  Arg His Ala 
    2510                 2515                 2520             


Asp His  Ser Ser Leu Thr Leu  Gly Ser Gly Ser Ser  Thr Thr Arg 
    2525                 2530                 2535             


Leu Thr  Gln Gly Ile Gly Arg  Ser Gln Arg Thr Leu  Arg Gln Leu 
    2540                 2545                 2550             


Thr Ala  Asn Thr Gly His Thr  Ile His Val His Tyr  Pro Gly Asn 
    2555                 2560                 2565             


Arg Gln  Pro Asn Pro Pro Leu  Ile Leu Gln Arg Leu  Leu Gly Pro 
    2570                 2575                 2580             


Ser Ala  Ala Ala Asp Ile Leu  Gln Leu Ser Ser Ser  Leu Pro Leu 
    2585                 2590                 2595             


Gln Ser  Arg Gly Arg Ala Arg  Leu Leu Val Gly Asn  Asp Asp Val 
    2600                 2605                 2610             


His Ile  Ile Ala Arg Ser Asp  Asp Glu Leu Leu Asp  Asp Phe Phe 
    2615                 2620                 2625             


His Asp  Gln Ser Thr Ala Thr  Ser Gln Ala Gly Thr  Leu Ser Ser 
    2630                 2635                 2640             


Ile Pro  Thr Ala Leu Thr Arg  Trp Thr Glu Glu Cys  Lys Val Leu 
    2645                 2650                 2655             


Asp Ala  Glu Ser Met His Asp  Cys Val Ser Val Val  Lys Val Ser 
    2660                 2665                 2670             


Ile Val  Asn His Leu Glu Phe  Leu Arg Asp Glu Glu  Leu Glu Glu 
    2675                 2680                 2685             


Arg Arg  Glu Lys Arg Arg Lys  Gln Leu Ala Glu Glu  Glu Thr Lys 
    2690                 2695                 2700             


Ile Thr  Asp Lys Gly Lys Glu  Asp Lys Glu Asn Arg  Asp Gln Ser 
    2705                 2710                 2715             


Ala Gln  Cys Thr Ala Ser Lys  Ser Asn Asp Ser Thr  Glu Gln Asn 
    2720                 2725                 2730             


Leu Ser  Asp Gly Thr Pro Met  Pro Asp Ser Tyr Pro  Thr Thr Pro 
    2735                 2740                 2745             


Ser Ser  Thr Asp Ala Ala Thr  Ser Glu Ser Lys Glu  Thr Leu Gly 
    2750                 2755                 2760             


Thr Leu  Gln Ser Ser Gln Gln  Gln Pro Thr Leu Pro  Thr Pro Pro 
    2765                 2770                 2775             


Ala Leu  Gly Glu Val Pro Gln  Glu Leu Gln Ser Pro  Ala Gly Glu 
    2780                 2785                 2790             


Gly Gly  Ser Ser Thr Gln Leu  Leu Met Pro Val Glu  Pro Glu Glu 
    2795                 2800                 2805             


Leu Gly  Pro Thr Arg Pro Ser  Gly Glu Ala Glu Thr  Thr Gln Met 
    2810                 2815                 2820             


Glu Leu  Ser Pro Ala Pro Thr  Ile Thr Ser Leu Ser  Pro Glu Arg 
    2825                 2830                 2835             


Ala Glu  Asp Ser Asp Ala Leu  Thr Ala Val Ser Ser  Gln Leu Glu 
    2840                 2845                 2850             


Gly Ser  Pro Met Asp Thr Ser  Ser Leu Ala Ser Cys  Thr Leu Glu 
    2855                 2860                 2865             


Glu Ala  Val Gly Asp Thr Ser  Ala Ala Gly Ser Ser  Glu Gln Pro 
    2870                 2875                 2880             


Arg Ala  Gly Ser Ser Thr Pro  Gly Asp Ala Pro Pro  Ala Val Ala 
    2885                 2890                 2895             


Glu Val  Gln Gly Arg Ser Asp  Gly Ser Gly Glu Ser  Ala Gln Pro 
    2900                 2905                 2910             


Pro Glu  Asp Ser Ser Pro Pro  Ala Ser Ser Glu Ser  Ser Ser Thr 
    2915                 2920                 2925             


Arg Asp  Ser Ala Val Ala Ile  Ser Gly Ala Asp Ser  Arg Gly Ile 
    2930                 2935                 2940             


Leu Glu  Glu Pro Leu Pro Ser  Thr Ser Ser Glu Glu  Glu Asp Pro 
    2945                 2950                 2955             


Leu Ala  Gly Ile Ser Leu Pro  Glu Gly Val Asp Pro  Ser Phe Leu 
    2960                 2965                 2970             


Ala Ala  Leu Pro Asp Asp Ile  Arg Arg Glu Val Leu  Gln Asn Gln 
    2975                 2980                 2985             


Leu Gly  Ile Arg Pro Pro Thr  Arg Thr Ala Pro Ser  Thr Asn Ser 
    2990                 2995                 3000             


Ser Ala  Pro Ala Val Val Gly  Asn Pro Gly Val Thr  Glu Val Ser 
    3005                 3010                 3015             


Pro Glu  Phe Leu Ala Ala Leu  Pro Pro Ala Ile Gln  Glu Glu Val 
    3020                 3025                 3030             


Leu Ala  Gln Gln Arg Ala Glu  Gln Gln Arg Arg Glu  Leu Ala Gln 
    3035                 3040                 3045             


Asn Ala  Ser Ser Asp Thr Pro  Met Asp Pro Val Thr  Phe Ile Gln 
    3050                 3055                 3060             


Thr Leu  Pro Ser Asp Leu Arg  Arg Ser Val Leu Glu  Asp Met Glu 
    3065                 3070                 3075             


Asp Ser  Val Leu Ala Val Met  Pro Pro Asp Ile Ala  Ala Glu Ala 
    3080                 3085                 3090             


Gln Ala  Leu Arg Arg Glu Gln  Glu Ala Arg Gln Arg  Gln Leu Met 
    3095                 3100                 3105             


His Glu  Arg Leu Phe Gly His  Ser Ser Thr Ser Ala  Leu Ser Ala 
    3110                 3115                 3120             


Ile Leu  Arg Ser Pro Ala Phe  Thr Ser Arg Leu Ser  Gly Asn Arg 
    3125                 3130                 3135             


Gly Val  Gln Tyr Thr Arg Leu  Ala Val Gln Arg Gly  Gly Thr Phe 
    3140                 3145                 3150             


Gln Met  Gly Gly Ser Ser Ser  His Asn Arg Pro Ser  Gly Ser Asn 
    3155                 3160                 3165             


Val Asp  Thr Leu Leu Arg Leu  Arg Gly Arg Leu Leu  Leu Asp His 
    3170                 3175                 3180             


Glu Ala  Leu Ser Cys Leu Leu  Val Leu Leu Phe Val  Asp Glu Pro 
    3185                 3190                 3195             


Lys Leu  Asn Thr Ser Arg Leu  His Arg Val Leu Arg  Asn Leu Cys 
    3200                 3205                 3210             


Tyr His  Ala Gln Thr Arg His  Trp Val Ile Arg Ser  Leu Leu Ser 
    3215                 3220                 3225             


Ile Leu  Gln Arg Ser Ser Glu  Ser Glu Leu Cys Ile  Glu Thr Pro 
    3230                 3235                 3240             


Lys Leu  Thr Thr Ser Glu Glu  Lys Gly Lys Lys Ser  Ser Lys Ser 
    3245                 3250                 3255             


Cys Gly  Ser Ser Ser His Glu  Asn Arg Pro Leu Asp  Leu Leu His 
    3260                 3265                 3270             


Lys Met  Glu Ser Lys Ser Ser  Asn Gln Leu Ser Trp  Leu Ser Val 
    3275                 3280                 3285             


Ser Met  Asp Ala Ala Leu Gly  Cys Arg Thr Asn Ile  Phe Gln Ile 
    3290                 3295                 3300             


Gln Arg  Ser Gly Gly Arg Lys  His Thr Glu Lys His  Ala Ser Gly 
    3305                 3310                 3315             


Gly Ser  Thr Val His Ile His  Pro Gln Ala Ala Pro  Val Val Cys 
    3320                 3325                 3330             


Arg His  Val Leu Asp Thr Leu  Ile Gln Leu Ala Lys  Val Phe Pro 
    3335                 3340                 3345             


Ser His  Phe Thr Gln Gln Arg  Thr Lys Glu Thr Asn  Cys Glu Ser 
    3350                 3355                 3360             


Asp Arg  Glu Arg Gly Asn Lys  Ala Cys Ser Pro Cys  Ser Ser Gln 
    3365                 3370                 3375             


Ser Ser  Ser Ser Gly Ile Cys  Thr Asp Phe Trp Asp  Leu Leu Val 
    3380                 3385                 3390             


Lys Leu  Asp Asn Met Asn Val  Ser Arg Lys Gly Lys  Asn Ser Val 
    3395                 3400                 3405             


Lys Ser  Val Pro Val Ser Ala  Gly Gly Glu Gly Glu  Thr Ser Pro 
    3410                 3415                 3420             


Tyr Ser  Leu Glu Ala Ser Pro  Leu Gly Gln Leu Met  Asn Met Leu 
    3425                 3430                 3435             


Ser His  Pro Val Ile Arg Arg  Ser Ser Leu Leu Thr  Glu Lys Leu 
    3440                 3445                 3450             


Leu Arg  Leu Leu Ser Leu Ile  Ser Ile Ala Leu Pro  Glu Asn Lys 
    3455                 3460                 3465             


Val Ser  Glu Ala Gln Ala Asn  Ser Gly Ser Gly Ala  Ser Ser Thr 
    3470                 3475                 3480             


Thr Thr  Ala Thr Ser Thr Thr  Ser Thr Thr Thr Thr  Thr Ala Ala 
    3485                 3490                 3495             


Ser Thr  Thr Pro Thr Pro Pro  Thr Ala Pro Thr Pro  Val Thr Ser 
    3500                 3505                 3510             


Ala Pro  Ala Leu Val Ala Ala  Thr Ala Ile Ser Thr  Ile Val Val 
    3515                 3520                 3525             


Ala Ala  Ser Thr Thr Val Thr  Thr Pro Thr Thr Ala  Thr Thr Thr 
    3530                 3535                 3540             


Val Ser  Ile Ser Pro Thr Thr  Lys Gly Ser Lys Ser  Pro Ala Lys 
    3545                 3550                 3555             


Val Ser  Asp Gly Gly Ser Ser  Ser Thr Asp Phe Lys  Met Val Ser 
    3560                 3565                 3570             


Ser Gly  Leu Thr Glu Asn Gln  Leu Gln Leu Ser Val  Glu Val Leu 
    3575                 3580                 3585             


Thr Ser  His Ser Cys Ser Glu  Glu Gly Leu Glu Asp  Ala Ala Asn 
    3590                 3595                 3600             


Val Leu  Leu Gln Leu Ser Arg  Gly Asp Ser Gly Thr  Arg Asp Thr 
    3605                 3610                 3615             


Val Leu  Lys Leu Leu Leu Asn  Gly Ala Arg His Leu  Gly Tyr Thr 
    3620                 3625                 3630             


Leu Cys  Lys Gln Ile Gly Thr  Leu Leu Ala Glu Leu  Arg Glu Tyr 
    3635                 3640                 3645             


Asn Leu  Glu Gln Gln Arg Arg  Ala Gln Cys Glu Thr  Leu Ser Pro 
    3650                 3655                 3660             


Asp Gly  Leu Pro Glu Glu Gln  Pro Gln Thr Thr Lys  Leu Lys Gly 
    3665                 3670                 3675             


Lys Met  Gln Ser Arg Phe Asp  Met Ala Glu Asn Val  Val Ile Val 
    3680                 3685                 3690             


Ala Ser  Gln Lys Arg Pro Leu  Gly Gly Arg Glu Leu  Gln Leu Pro 
    3695                 3700                 3705             


Ser Met  Ser Met Leu Thr Ser  Lys Thr Ser Thr Gln  Lys Phe Phe 
    3710                 3715                 3720             


Leu Arg  Val Leu Gln Val Ile  Ile Gln Leu Arg Asp  Asp Thr Arg 
    3725                 3730                 3735             


Arg Ala  Asn Lys Lys Ala Lys  Gln Thr Gly Arg Leu  Gly Ser Ser 
    3740                 3745                 3750             


Gly Leu  Gly Ser Ala Ser Ser  Ile Gln Ala Ala Val  Arg Gln Leu 
    3755                 3760                 3765             


Glu Ala  Glu Ala Asp Ala Ile  Ile Gln Met Val Arg  Glu Gly Gln 
    3770                 3775                 3780             


Arg Ala  Arg Arg Gln Gln Gln  Ala Ala Thr Ser Glu  Ser Ser Gln 
    3785                 3790                 3795             


Ser Glu  Ala Ser Val Arg Arg  Glu Glu Ser Pro Met  Asp Val Asp 
    3800                 3805                 3810             


Gln Pro  Ser Pro Ser Ala Gln  Asp Thr Gln Ser Ile  Ala Ser Asp 
    3815                 3820                 3825             


Gly Thr  Pro Gln Gly Glu Lys  Glu Lys Glu Glu Arg  Pro Pro Glu 
    3830                 3835                 3840             


Leu Pro  Leu Leu Ser Glu Gln  Leu Ser Leu Asp Glu  Leu Trp Asp 
    3845                 3850                 3855             


Met Leu  Gly Glu Cys Leu Lys  Glu Leu Glu Glu Ser  His Asp Gln 
    3860                 3865                 3870             


His Ala  Val Leu Val Leu Gln  Pro Ala Val Glu Ala  Phe Phe Leu 
    3875                 3880                 3885             


Val His  Ala Thr Glu Arg Glu  Ser Lys Pro Pro Val  Arg Asp Thr 
    3890                 3895                 3900             


Arg Glu  Ser Gln Leu Ala His  Ile Lys Asp Glu Pro  Pro Pro Leu 
    3905                 3910                 3915             


Ser Pro  Ala Pro Leu Thr Pro  Ala Thr Pro Ser Ser  Leu Asp Pro 
    3920                 3925                 3930             


Phe Phe  Ser Arg Glu Pro Ser  Ser Met His Ile Ser  Ser Ser Leu 
    3935                 3940                 3945             


Pro Pro  Asp Thr Gln Lys Phe  Leu Arg Phe Ala Glu  Thr His Arg 
    3950                 3955                 3960             


Thr Val  Leu Asn Gln Ile Leu  Arg Gln Ser Thr Thr  His Leu Ala 
    3965                 3970                 3975             


Asp Gly  Pro Phe Ala Val Leu  Val Asp Tyr Ile Arg  Val Leu Asp 
    3980                 3985                 3990             


Phe Asp  Val Lys Arg Lys Tyr  Phe Arg Gln Glu Leu  Glu Arg Leu 
    3995                 4000                 4005             


Asp Glu  Gly Leu Arg Lys Glu  Asp Met Ala Val His  Val Arg Arg 
    4010                 4015                 4020             


Asp His  Val Phe Glu Asp Ser  Tyr Arg Glu Leu His  Arg Lys Ser 
    4025                 4030                 4035             


Pro Glu  Glu Met Lys Asn Arg  Leu Tyr Ile Val Phe  Glu Gly Glu 
    4040                 4045                 4050             


Glu Gly  Gln Asp Ala Gly Gly  Leu Leu Arg Glu Trp  Tyr Met Ile 
    4055                 4060                 4065             


Ile Ser  Arg Glu Met Phe Asn  Pro Met Tyr Ala Leu  Phe Arg Thr 
    4070                 4075                 4080             


Ser Pro  Gly Asp Arg Val Thr  Tyr Thr Ile Asn Pro  Ser Ser His 
    4085                 4090                 4095             


Cys Asn  Pro Asn His Leu Ser  Tyr Phe Lys Phe Val  Gly Arg Ile 
    4100                 4105                 4110             


Val Ala  Lys Ala Val Tyr Asp  Asn Arg Leu Leu Glu  Cys Tyr Phe 
    4115                 4120                 4125             


Thr Arg  Ser Phe Tyr Lys His  Ile Leu Gly Lys Ser  Val Arg Tyr 
    4130                 4135                 4140             


Thr Asp  Met Glu Ser Glu Asp  Tyr His Phe Tyr Gln  Gly Leu Val 
    4145                 4150                 4155             


Tyr Leu  Leu Glu Asn Asp Val  Ser Thr Leu Gly Tyr  Asp Leu Thr 
    4160                 4165                 4170             


Phe Ser  Thr Glu Val Gln Glu  Phe Gly Val Cys Glu  Val Arg Asp 
    4175                 4180                 4185             


Leu Lys  Pro Asn Gly Ala Asn  Ile Leu Val Thr Glu  Glu Asn Lys 
    4190                 4195                 4200             


Lys Glu  Tyr Val His Leu Val  Cys Gln Met Arg Met  Thr Gly Ala 
    4205                 4210                 4215             


Ile Arg  Lys Gln Leu Ala Ala  Phe Leu Glu Gly Phe  Tyr Glu Ile 
    4220                 4225                 4230             


Ile Pro  Lys Arg Leu Ile Ser  Ile Phe Thr Glu Gln  Glu Leu Glu 
    4235                 4240                 4245             


Leu Leu  Ile Ser Gly Leu Pro  Thr Ile Asp Ile Asp  Asp Leu Lys 
    4250                 4255                 4260             


Ser Asn  Thr Glu Tyr His Lys  Tyr Gln Ser Asn Ser  Ile Gln Ile 
    4265                 4270                 4275             


Gln Trp  Phe Trp Arg Ala Leu  Arg Ser Phe Asp Gln  Ala Asp Arg 
    4280                 4285                 4290             


Ala Lys  Phe Leu Gln Phe Val  Thr Gly Thr Ser Lys  Val Pro Leu 
    4295                 4300                 4305             


Gln Gly  Phe Ala Ala Leu Glu  Gly Met Asn Gly Ile  Gln Lys Phe 
    4310                 4315                 4320             


Gln Ile  His Arg Asp Asp Arg  Ser Thr Asp Arg Leu  Pro Ser Ala 
    4325                 4330                 4335             


His Thr  Cys Phe Asn Gln Leu  Asp Leu Pro Ala Tyr  Glu Ser Phe 
    4340                 4345                 4350             


Glu Lys  Leu Arg His Met Leu  Leu Leu Ala Ile Gln  Glu Cys Ser 
    4355                 4360                 4365             


Glu Gly  Phe Gly Leu Ala 
    4370                 


<210>  1555
<211>  300
<212>  PRT
<213>  Homo sapiens

<400>  1555

Met Ile Leu Leu Glu Val Asn Asn Arg Ile Ile Glu Glu Thr Leu Ala 
1               5                   10                  15      


Leu Lys Phe Glu Asn Ala Ala Ala Gly Asn Lys Pro Glu Ala Val Glu 
            20                  25                  30          


Val Thr Phe Ala Asp Phe Asp Gly Val Leu Tyr His Ile Ser Asn Pro 
        35                  40                  45              


Asn Gly Asp Lys Thr Lys Val Met Val Ser Ile Ser Leu Lys Phe Tyr 
    50                  55                  60                  


Lys Glu Leu Gln Ala His Gly Ala Asp Glu Leu Leu Lys Arg Val Tyr 
65                  70                  75                  80  


Gly Ser Phe Leu Val Asn Pro Glu Ser Gly Tyr Asn Val Ser Leu Leu 
                85                  90                  95      


Tyr Asp Leu Glu Asn Leu Pro Ala Ser Lys Asp Ser Ile Val His Gln 
            100                 105                 110         


Ala Gly Met Leu Lys Arg Asn Cys Phe Ala Ser Val Phe Glu Lys Tyr 
        115                 120                 125             


Phe Gln Phe Gln Glu Glu Gly Lys Glu Gly Glu Asn Arg Ala Val Ile 
    130                 135                 140                 


His Tyr Arg Asp Asp Glu Thr Met Tyr Val Glu Ser Lys Lys Asp Arg 
145                 150                 155                 160 


Val Thr Val Val Phe Ser Thr Val Phe Lys Asp Asp Asp Asp Val Val 
                165                 170                 175     


Ile Gly Lys Val Phe Met Gln Glu Phe Lys Glu Gly Arg Arg Ala Ser 
            180                 185                 190         


His Thr Ala Pro Gln Val Leu Phe Ser His Arg Glu Pro Pro Leu Glu 
        195                 200                 205             


Leu Lys Asp Thr Asp Ala Ala Val Gly Asp Asn Ile Gly Tyr Ile Thr 
    210                 215                 220                 


Phe Val Leu Phe Pro Arg His Thr Asn Ala Ser Ala Arg Asp Asn Thr 
225                 230                 235                 240 


Ile Asn Leu Ile His Thr Phe Arg Asp Tyr Leu His Tyr His Ile Lys 
                245                 250                 255     


Cys Ser Lys Ala Tyr Ile His Thr Arg Met Arg Ala Lys Thr Ser Asp 
            260                 265                 270         


Phe Leu Lys Val Leu Asn Arg Ala Arg Pro Asp Ala Glu Lys Lys Glu 
        275                 280                 285             


Met Lys Thr Ile Thr Gly Lys Thr Phe Ser Ser Arg 
    290                 295                 300 


<210>  1556
<211>  1123
<212>  PRT
<213>  Homo sapiens

<400>  1556

Met Trp Gly Asp Ser Arg Pro Ala Asn Arg Thr Gly Pro Phe Arg Gly 
1               5                   10                  15      


Ser Gln Glu Glu Arg Phe Ala Pro Gly Trp Asn Arg Asp Tyr Pro Pro 
            20                  25                  30          


Pro Pro Leu Lys Ser His Ala Gln Glu Arg His Ser Gly Asn Phe Pro 
        35                  40                  45              


Gly Arg Asp Ser Leu Pro Phe Asp Phe Gln Gly His Ser Gly Pro Pro 
    50                  55                  60                  


Phe Ala Asn Val Glu Glu His Ser Phe Ser Tyr Gly Ala Arg Asp Gly 
65                  70                  75                  80  


Pro His Gly Asp Tyr Arg Gly Gly Glu Gly Pro Gly His Asp Phe Arg 
                85                  90                  95      


Gly Gly Asp Phe Ser Ser Ser Asp Phe Gln Ser Arg Asp Ser Ser Gln 
            100                 105                 110         


Leu Asp Phe Arg Gly Arg Asp Ile His Ser Gly Asp Phe Arg Asp Arg 
        115                 120                 125             


Glu Gly Pro Pro Met Asp Tyr Arg Gly Gly Asp Gly Thr Ser Met Asp 
    130                 135                 140                 


Tyr Arg Gly Arg Glu Ala Pro His Met Asn Tyr Arg Asp Arg Asp Ala 
145                 150                 155                 160 


His Ala Val Asp Phe Arg Gly Arg Asp Ala Pro Pro Ser Asp Phe Arg 
                165                 170                 175     


Gly Arg Gly Thr Tyr Asp Leu Asp Phe Arg Gly Arg Asp Gly Ser His 
            180                 185                 190         


Ala Asp Phe Arg Gly Arg Asp Leu Ser Asp Leu Asp Phe Arg Ala Arg 
        195                 200                 205             


Glu Gln Ser Arg Ser Asp Phe Arg Asn Arg Asp Val Ser Asp Leu Asp 
    210                 215                 220                 


Phe Arg Asp Lys Asp Gly Thr Gln Val Asp Phe Arg Gly Arg Gly Ser 
225                 230                 235                 240 


Gly Thr Thr Asp Leu Asp Phe Arg Asp Arg Asp Thr Pro His Ser Asp 
                245                 250                 255     


Phe Arg Gly Arg His Arg Ser Arg Thr Asp Gln Asp Phe Arg Gly Arg 
            260                 265                 270         


Glu Met Gly Ser Cys Met Glu Phe Lys Asp Arg Glu Met Pro Pro Val 
        275                 280                 285             


Asp Pro Asn Ile Leu Asp Tyr Ile Gln Pro Ser Thr Gln Asp Arg Glu 
    290                 295                 300                 


His Ser Gly Met Asn Val Asn Arg Arg Glu Glu Ser Thr His Asp His 
305                 310                 315                 320 


Thr Ile Glu Arg Pro Ala Phe Gly Ile Gln Lys Gly Glu Phe Glu His 
                325                 330                 335     


Ser Glu Thr Arg Glu Gly Glu Thr Gln Gly Val Ala Phe Glu His Glu 
            340                 345                 350         


Ser Pro Ala Asp Phe Gln Asn Ser Gln Ser Pro Val Gln Asp Gln Asp 
        355                 360                 365             


Lys Ser Gln Leu Ser Gly Arg Glu Glu Gln Ser Ser Asp Ala Gly Leu 
    370                 375                 380                 


Phe Lys Glu Glu Gly Gly Leu Asp Phe Leu Gly Arg Gln Asp Thr Asp 
385                 390                 395                 400 


Tyr Arg Ser Met Glu Tyr Arg Asp Val Asp His Arg Leu Pro Gly Ser 
                405                 410                 415     


Gln Met Phe Gly Tyr Gly Gln Ser Lys Ser Phe Pro Glu Gly Lys Thr 
            420                 425                 430         


Ala Arg Asp Ala Gln Arg Asp Leu Gln Asp Gln Asp Tyr Arg Thr Gly 
        435                 440                 445             


Pro Ser Glu Glu Lys Pro Ser Arg Leu Ile Arg Leu Ser Gly Val Pro 
    450                 455                 460                 


Glu Asp Ala Thr Lys Glu Glu Ile Leu Asn Ala Phe Arg Thr Pro Asp 
465                 470                 475                 480 


Gly Met Pro Val Lys Asn Leu Gln Leu Lys Glu Tyr Asn Thr Gly Tyr 
                485                 490                 495     


Asp Tyr Gly Tyr Val Cys Val Glu Phe Ser Leu Leu Glu Asp Ala Ile 
            500                 505                 510         


Gly Cys Met Glu Ala Asn Gln Gly Thr Leu Met Ile Gln Asp Lys Glu 
        515                 520                 525             


Val Thr Leu Glu Tyr Val Ser Ser Leu Asp Phe Trp Tyr Cys Lys Arg 
    530                 535                 540                 


Cys Lys Ala Asn Ile Gly Gly His Arg Ser Ser Cys Ser Phe Cys Lys 
545                 550                 555                 560 


Asn Pro Arg Glu Val Thr Glu Ala Lys Gln Glu Leu Ile Thr Tyr Pro 
                565                 570                 575     


Gln Pro Gln Lys Thr Ser Ile Pro Ala Pro Leu Glu Lys Gln Pro Asn 
            580                 585                 590         


Gln Pro Leu Arg Pro Ala Asp Lys Glu Pro Glu Pro Arg Lys Arg Glu 
        595                 600                 605             


Glu Gly Gln Glu Ser Arg Leu Gly His Gln Lys Arg Glu Ala Glu Arg 
    610                 615                 620                 


Tyr Leu Pro Pro Ser Arg Arg Glu Gly Pro Thr Phe Arg Arg Asp Arg 
625                 630                 635                 640 


Glu Arg Glu Ser Trp Ser Gly Glu Thr Arg Gln Asp Gly Glu Ser Lys 
                645                 650                 655     


Thr Ile Met Leu Lys Arg Ile Tyr Arg Ser Thr Pro Pro Glu Val Ile 
            660                 665                 670         


Val Glu Val Leu Glu Pro Tyr Val Arg Leu Thr Thr Ala Asn Val Arg 
        675                 680                 685             


Ile Ile Lys Asn Arg Thr Gly Pro Met Gly His Thr Tyr Gly Phe Ile 
    690                 695                 700                 


Asp Leu Asp Ser His Ala Glu Ala Leu Arg Val Val Lys Ile Leu Gln 
705                 710                 715                 720 


Asn Leu Asp Pro Pro Phe Ser Ile Asp Gly Lys Met Val Ala Val Asn 
                725                 730                 735     


Leu Ala Thr Gly Lys Arg Arg Asn Asp Ser Gly Asp His Ser Asp His 
            740                 745                 750         


Met His Tyr Tyr Gln Gly Lys Lys Tyr Phe Arg Asp Arg Arg Gly Gly 
        755                 760                 765             


Gly Arg Asn Ser Asp Trp Ser Ser Asp Thr Asn Arg Gln Gly Gln Gln 
    770                 775                 780                 


Ser Ser Ser Asp Cys Tyr Ile Tyr Asp Ser Ala Thr Gly Tyr Tyr Tyr 
785                 790                 795                 800 


Asp Pro Leu Ala Gly Thr Tyr Tyr Asp Pro Asn Thr Gln Gln Glu Val 
                805                 810                 815     


Tyr Val Pro Gln Asp Pro Gly Leu Pro Glu Glu Glu Glu Ile Lys Glu 
            820                 825                 830         


Lys Lys Pro Thr Ser Gln Gly Lys Ser Ser Ser Lys Lys Glu Met Ser 
        835                 840                 845             


Lys Arg Asp Gly Lys Glu Lys Lys Asp Arg Gly Val Thr Arg Phe Gln 
    850                 855                 860                 


Glu Asn Ala Ser Glu Gly Lys Ala Pro Ala Glu Asp Val Phe Lys Lys 
865                 870                 875                 880 


Pro Leu Pro Pro Thr Val Lys Lys Glu Glu Ser Pro Pro Pro Pro Lys 
                885                 890                 895     


Val Val Asn Pro Leu Ile Gly Leu Leu Gly Glu Tyr Gly Gly Asp Ser 
            900                 905                 910         


Asp Tyr Glu Glu Glu Glu Glu Glu Glu Gln Thr Pro Pro Pro Gln Pro 
        915                 920                 925             


Arg Thr Ala Gln Pro Gln Lys Arg Glu Glu Gln Thr Lys Lys Glu Asn 
    930                 935                 940                 


Glu Glu Asp Lys Leu Thr Asp Trp Asn Lys Leu Ala Cys Leu Leu Cys 
945                 950                 955                 960 


Arg Arg Gln Phe Pro Asn Lys Glu Val Leu Ile Lys His Gln Gln Leu 
                965                 970                 975     


Ser Asp Leu His Lys Gln Asn Leu Glu Ile His Arg Lys Ile Lys Gln 
            980                 985                 990         


Ser Glu Gln Glu Leu Ala Tyr Leu  Glu Arg Arg Glu Arg  Glu Gly Lys 
        995                 1000                 1005             


Phe Lys  Gly Arg Gly Asn Asp  Arg Arg Glu Lys Leu  Gln Ser Phe 
    1010                 1015                 1020             


Asp Ser  Pro Glu Arg Lys Arg  Ile Lys Tyr Ser Arg  Glu Thr Asp 
    1025                 1030                 1035             


Ser Asp  Arg Lys Leu Val Asp  Lys Glu Asp Ile Asp  Thr Ser Ser 
    1040                 1045                 1050             


Lys Gly  Gly Cys Val Gln Gln  Ala Thr Gly Trp Arg  Lys Gly Thr 
    1055                 1060                 1065             


Gly Leu  Gly Tyr Gly His Pro  Gly Leu Ala Ser Ser  Glu Glu Ala 
    1070                 1075                 1080             


Glu Gly  Arg Met Arg Gly Pro  Ser Val Gly Ala Ser  Gly Arg Thr 
    1085                 1090                 1095             


Ser Lys  Arg Gln Ser Asn Glu  Thr Tyr Arg Asp Ala  Val Arg Arg 
    1100                 1105                 1110             


Val Met  Phe Ala Arg Tyr Lys  Glu Leu Asp 
    1115                 1120             


<210>  1557
<211>  303
<212>  PRT
<213>  Homo sapiens

<400>  1557

Met Lys Gly Lys Glu Glu Lys Glu Gly Gly Ala Arg Leu Gly Ala Gly 
1               5                   10                  15      


Gly Gly Ser Pro Glu Lys Ser Pro Ser Ala Gln Glu Leu Lys Glu Gln 
            20                  25                  30          


Gly Asn Arg Leu Phe Val Gly Arg Lys Tyr Pro Glu Ala Ala Ala Cys 
        35                  40                  45              


Tyr Gly Arg Ala Ile Thr Arg Asn Pro Leu Val Ala Val Tyr Tyr Thr 
    50                  55                  60                  


Asn Arg Ala Leu Cys Tyr Leu Lys Met Gln Gln His Glu Gln Ala Leu 
65                  70                  75                  80  


Ala Asp Cys Arg Arg Ala Leu Glu Leu Asp Gly Gln Ser Val Lys Ala 
                85                  90                  95      


His Phe Phe Leu Gly Gln Cys Gln Leu Glu Met Glu Ser Tyr Asp Glu 
            100                 105                 110         


Ala Ile Ala Asn Leu Gln Arg Ala Tyr Ser Leu Ala Lys Glu Gln Arg 
        115                 120                 125             


Leu Asn Phe Gly Asp Asp Ile Pro Ser Ala Leu Arg Ile Ala Lys Lys 
    130                 135                 140                 


Lys Arg Trp Asn Ser Ile Glu Glu Arg Arg Ile His Gln Glu Ser Glu 
145                 150                 155                 160 


Leu His Ser Tyr Leu Ser Arg Leu Ile Ala Ala Glu Arg Glu Arg Glu 
                165                 170                 175     


Leu Glu Glu Cys Gln Arg Asn His Glu Gly Asp Glu Asp Asp Ser His 
            180                 185                 190         


Val Arg Ala Gln Gln Ala Cys Ile Glu Ala Lys His Asp Lys Tyr Met 
        195                 200                 205             


Ala Asp Met Asp Glu Leu Phe Ser Gln Val Asp Glu Lys Arg Lys Lys 
    210                 215                 220                 


Arg Asp Ile Pro Asp Tyr Leu Cys Gly Lys Ile Ser Phe Glu Leu Met 
225                 230                 235                 240 


Arg Glu Pro Cys Ile Thr Pro Ser Gly Ile Thr Tyr Asp Arg Lys Asp 
                245                 250                 255     


Ile Glu Glu His Leu Gln Arg Val Gly His Phe Asp Pro Val Thr Arg 
            260                 265                 270         


Ser Pro Leu Thr Gln Glu Gln Leu Ile Pro Asn Leu Ala Met Lys Glu 
        275                 280                 285             


Val Ile Asp Ala Phe Ile Ser Glu Asn Gly Trp Val Glu Asp Tyr 
    290                 295                 300             


<210>  1558
<211>  669
<212>  PRT
<213>  Homo sapiens

<400>  1558

Met Lys Ile Phe Val Gly Asn Val Asp Gly Ala Asp Thr Thr Pro Glu 
1               5                   10                  15      


Glu Leu Ala Ala Leu Phe Ala Pro Tyr Gly Thr Val Met Ser Cys Ala 
            20                  25                  30          


Val Met Lys Gln Phe Ala Phe Val His Met Arg Glu Asn Ala Gly Ala 
        35                  40                  45              


Leu Arg Ala Ile Glu Ala Leu His Gly His Glu Leu Arg Pro Gly Arg 
    50                  55                  60                  


Ala Leu Val Val Glu Met Ser Arg Pro Arg Pro Leu Asn Thr Trp Lys 
65                  70                  75                  80  


Ile Phe Val Gly Asn Val Ser Ala Ala Cys Thr Ser Gln Glu Leu Arg 
                85                  90                  95      


Ser Leu Phe Glu Arg Arg Gly Arg Val Ile Glu Cys Asp Val Val Lys 
            100                 105                 110         


Asp Tyr Ala Phe Val His Met Glu Lys Glu Ala Asp Ala Lys Ala Ala 
        115                 120                 125             


Ile Ala Gln Leu Asn Gly Lys Glu Val Lys Gly Lys Arg Ile Asn Val 
    130                 135                 140                 


Glu Leu Ser Thr Lys Gly Gln Lys Lys Gly Pro Gly Leu Ala Val Gln 
145                 150                 155                 160 


Ser Gly Asp Lys Thr Lys Lys Pro Gly Ala Gly Asp Thr Ala Phe Pro 
                165                 170                 175     


Gly Thr Gly Gly Phe Ser Ala Thr Phe Asp Tyr Gln Gln Ala Phe Gly 
            180                 185                 190         


Asn Ser Thr Gly Gly Phe Asp Gly Gln Ala Arg Gln Pro Thr Pro Pro 
        195                 200                 205             


Phe Phe Gly Arg Asp Arg Ser Pro Leu Arg Arg Ser Pro Pro Arg Ala 
    210                 215                 220                 


Ser Tyr Val Ala Pro Leu Thr Ala Gln Pro Ala Thr Tyr Arg Ala Gln 
225                 230                 235                 240 


Pro Ser Val Ser Leu Gly Ala Ala Tyr Arg Ala Gln Pro Ser Ala Ser 
                245                 250                 255     


Leu Gly Val Gly Tyr Arg Thr Gln Pro Met Thr Ala Gln Ala Ala Ser 
            260                 265                 270         


Tyr Arg Ala Gln Pro Ser Val Ser Leu Gly Ala Pro Tyr Arg Gly Gln 
        275                 280                 285             


Leu Ala Ser Pro Ser Ser Gln Ser Ala Ala Ala Ser Ser Leu Gly Pro 
    290                 295                 300                 


Tyr Gly Gly Ala Gln Pro Ser Ala Ser Ala Leu Ser Ser Tyr Gly Gly 
305                 310                 315                 320 


Gln Ala Ala Ala Ala Ser Ser Leu Asn Ser Tyr Gly Ala Gln Gly Ser 
                325                 330                 335     


Ser Leu Ala Ser Tyr Gly Asn Gln Pro Ser Ser Tyr Gly Ala Gln Ala 
            340                 345                 350         


Ala Ser Ser Tyr Gly Val Arg Ala Ala Ala Ser Ser Tyr Asn Thr Gln 
        355                 360                 365             


Gly Ala Ala Ser Ser Leu Gly Ser Tyr Gly Ala Gln Ala Ala Ser Tyr 
    370                 375                 380                 


Gly Ala Gln Ser Ala Ala Ser Ser Leu Ala Tyr Gly Ala Gln Ala Ala 
385                 390                 395                 400 


Ser Tyr Asn Ala Gln Pro Ser Ala Ser Tyr Asn Ala Gln Ser Ala Pro 
                405                 410                 415     


Tyr Ala Ala Gln Gln Ala Ala Ser Tyr Ser Ser Gln Pro Ala Ala Tyr 
            420                 425                 430         


Val Ala Gln Pro Ala Thr Ala Ala Ala Tyr Ala Ser Gln Pro Ala Ala 
        435                 440                 445             


Tyr Ala Ala Gln Ala Thr Thr Pro Met Ala Gly Ser Tyr Gly Ala Gln 
    450                 455                 460                 


Pro Val Val Gln Thr Gln Leu Asn Ser Tyr Gly Ala Gln Ala Ser Met 
465                 470                 475                 480 


Gly Leu Ser Gly Ser Tyr Gly Ala Gln Ser Ala Ala Ala Ala Thr Gly 
                485                 490                 495     


Ser Tyr Gly Ala Ala Ala Ala Tyr Gly Ala Gln Pro Ser Ala Thr Leu 
            500                 505                 510         


Ala Ala Pro Tyr Arg Thr Gln Ser Ser Ala Ser Leu Ala Ala Ser Tyr 
        515                 520                 525             


Ala Ala Gln Gln His Pro Gln Ala Ala Ala Ser Tyr Arg Gly Gln Pro 
    530                 535                 540                 


Gly Asn Ala Tyr Asp Gly Ala Gly Gln Pro Ser Ala Ala Tyr Leu Ser 
545                 550                 555                 560 


Met Ser Gln Gly Ala Val Ala Asn Ala Asn Ser Thr Pro Pro Pro Tyr 
                565                 570                 575     


Glu Arg Thr Arg Leu Ser Pro Pro Arg Ala Ser Tyr Asp Asp Pro Tyr 
            580                 585                 590         


Lys Lys Ala Val Ala Met Ser Lys Arg Tyr Gly Ser Asp Arg Arg Leu 
        595                 600                 605             


Ala Glu Leu Ser Asp Tyr Arg Arg Leu Ser Glu Ser Gln Leu Ser Phe 
    610                 615                 620                 


Arg Arg Ser Pro Thr Lys Ser Ser Leu Asp Tyr Arg Arg Leu Pro Asp 
625                 630                 635                 640 


Ala His Ser Asp Tyr Ala Arg Tyr Ser Gly Ser Tyr Asn Asp Tyr Leu 
                645                 650                 655     


Arg Ala Ala Gln Met His Ser Gly Tyr Gln Arg Arg Met 
            660                 665                 


<210>  1559
<211>  335
<212>  PRT
<213>  Homo sapiens

<400>  1559

Met Ala Ala Gly Ala Ala Glu Ala Ala Val Ala Ala Val Glu Glu Val 
1               5                   10                  15      


Gly Ser Ala Gly Gln Phe Glu Glu Leu Leu Arg Leu Lys Ala Lys Ser 
            20                  25                  30          


Leu Leu Val Val His Phe Trp Ala Pro Trp Ala Pro Gln Cys Ala Gln 
        35                  40                  45              


Met Asn Glu Val Met Ala Glu Leu Ala Lys Glu Leu Pro Gln Val Ser 
    50                  55                  60                  


Phe Val Lys Leu Glu Ala Glu Gly Val Pro Glu Val Ser Glu Lys Tyr 
65                  70                  75                  80  


Glu Ile Ser Ser Val Pro Thr Phe Leu Phe Phe Lys Asn Ser Gln Lys 
                85                  90                  95      


Ile Asp Arg Leu Asp Gly Ala His Ala Pro Glu Leu Thr Lys Lys Val 
            100                 105                 110         


Gln Arg His Ala Ser Ser Gly Ser Phe Leu Pro Ser Ala Asn Glu His 
        115                 120                 125             


Leu Lys Glu Asp Leu Asn Leu Arg Leu Lys Lys Leu Thr His Ala Ala 
    130                 135                 140                 


Pro Cys Met Leu Phe Met Lys Gly Thr Pro Gln Glu Pro Arg Cys Gly 
145                 150                 155                 160 


Phe Ser Lys Gln Met Val Glu Ile Leu His Lys His Asn Ile Gln Phe 
                165                 170                 175     


Ser Ser Phe Asp Ile Phe Ser Asp Glu Glu Val Arg Gln Gly Leu Lys 
            180                 185                 190         


Ala Tyr Ser Ser Trp Pro Thr Tyr Pro Gln Leu Tyr Val Ser Gly Glu 
        195                 200                 205             


Leu Ile Gly Gly Leu Asp Ile Ile Lys Glu Leu Glu Ala Ser Glu Glu 
    210                 215                 220                 


Leu Asp Thr Ile Cys Pro Lys Ala Pro Lys Leu Glu Glu Arg Leu Lys 
225                 230                 235                 240 


Val Leu Thr Asn Lys Ala Ser Val Met Leu Phe Met Lys Gly Asn Lys 
                245                 250                 255     


Gln Glu Ala Lys Cys Gly Phe Ser Lys Gln Ile Leu Glu Ile Leu Asn 
            260                 265                 270         


Ser Thr Gly Val Glu Tyr Glu Thr Phe Asp Ile Leu Glu Asp Glu Glu 
        275                 280                 285             


Val Arg Gln Gly Leu Lys Ala Tyr Ser Asn Trp Pro Thr Tyr Pro Gln 
    290                 295                 300                 


Leu Tyr Val Lys Gly Glu Leu Val Gly Gly Leu Asp Ile Val Lys Glu 
305                 310                 315                 320 


Leu Lys Glu Asn Gly Glu Leu Leu Pro Ile Leu Arg Gly Glu Asn 
                325                 330                 335 


<210>  1560
<211>  713
<212>  PRT
<213>  Homo sapiens

<400>  1560

Met Ala Lys Ser Pro Glu Asn Ser Thr Leu Glu Glu Ile Leu Gly Gln 
1               5                   10                  15      


Tyr Gln Arg Ser Leu Arg Glu His Ala Ser Arg Ser Ile His Gln Leu 
            20                  25                  30          


Thr Cys Ala Leu Lys Glu Gly Asp Val Thr Ile Gly Glu Asp Ala Pro 
        35                  40                  45              


Asn Leu Ser Phe Ser Thr Ser Val Gly Asn Glu Asp Ala Arg Thr Ala 
    50                  55                  60                  


Trp Pro Glu Leu Gln Gln Ser His Ala Val Asn Gln Leu Lys Asp Leu 
65                  70                  75                  80  


Leu Arg Gln Gln Ala Asp Lys Glu Ser Glu Val Ser Pro Ser Arg Arg 
                85                  90                  95      


Arg Lys Met Ser Pro Leu Arg Ser Leu Glu His Glu Glu Thr Asn Met 
            100                 105                 110         


Pro Thr Met His Asp Leu Val His Thr Ile Asn Asp Gln Ser Gln Tyr 
        115                 120                 125             


Ile His His Leu Glu Ala Glu Val Lys Phe Cys Lys Glu Glu Leu Ser 
    130                 135                 140                 


Gly Met Lys Asn Lys Ile Gln Val Val Val Leu Glu Asn Glu Gly Leu 
145                 150                 155                 160 


Gln Gln Gln Leu Lys Ser Gln Arg Gln Glu Glu Thr Leu Arg Glu Gln 
                165                 170                 175     


Thr Leu Leu Asp Ala Ser Gly Asn Met His Asn Ser Trp Ile Thr Thr 
            180                 185                 190         


Gly Glu Asp Ser Gly Val Gly Glu Thr Ser Lys Arg Pro Phe Ser His 
        195                 200                 205             


Asp Asn Ala Asp Phe Gly Lys Ala Ala Ser Ala Gly Glu Gln Leu Glu 
    210                 215                 220                 


Leu Glu Lys Leu Lys Leu Thr Tyr Glu Glu Lys Cys Glu Ile Glu Glu 
225                 230                 235                 240 


Ser Gln Leu Lys Phe Leu Arg Asn Asp Leu Ala Glu Tyr Gln Arg Thr 
                245                 250                 255     


Cys Glu Asp Leu Lys Glu Gln Leu Lys His Lys Glu Phe Leu Leu Ala 
            260                 265                 270         


Ala Asn Thr Cys Asn Arg Val Gly Gly Leu Cys Leu Lys Cys Ala Gln 
        275                 280                 285             


His Glu Ala Val Leu Ser Gln Thr His Thr Asn Val His Met Gln Thr 
    290                 295                 300                 


Ile Glu Arg Leu Val Lys Glu Arg Asp Asp Leu Met Ser Ala Leu Val 
305                 310                 315                 320 


Ser Val Arg Ser Ser Leu Ala Asp Thr Gln Gln Arg Glu Ala Ser Ala 
                325                 330                 335     


Tyr Glu Gln Val Lys Gln Val Leu Gln Ile Ser Glu Glu Ala Asn Phe 
            340                 345                 350         


Glu Lys Thr Lys Ala Leu Ile Gln Cys Asp Gln Leu Arg Lys Glu Leu 
        355                 360                 365             


Glu Arg Gln Ala Glu Arg Leu Glu Lys Glu Leu Ala Ser Gln Gln Glu 
    370                 375                 380                 


Lys Arg Ala Ile Glu Lys Asp Met Met Lys Lys Glu Ile Thr Lys Glu 
385                 390                 395                 400 


Arg Glu Tyr Met Gly Ser Lys Met Leu Ile Leu Ser Gln Asn Ile Ala 
                405                 410                 415     


Gln Leu Glu Ala Gln Val Glu Lys Val Thr Lys Glu Lys Ile Ser Ala 
            420                 425                 430         


Ile Asn Gln Leu Glu Glu Ile Gln Ser Gln Leu Ala Ser Arg Glu Met 
        435                 440                 445             


Asp Val Thr Lys Val Cys Gly Glu Met Arg Tyr Gln Leu Asn Lys Thr 
    450                 455                 460                 


Asn Met Glu Lys Asp Glu Ala Glu Lys Glu His Arg Glu Phe Arg Ala 
465                 470                 475                 480 


Lys Thr Asn Arg Asp Leu Glu Ile Lys Asp Gln Glu Ile Glu Lys Leu 
                485                 490                 495     


Arg Ile Glu Leu Asp Glu Ser Lys Gln His Leu Glu Gln Glu Gln Gln 
            500                 505                 510         


Lys Ala Ala Leu Ala Arg Glu Glu Cys Leu Arg Leu Thr Glu Leu Leu 
        515                 520                 525             


Gly Glu Ser Glu His Gln Leu His Leu Thr Arg Gln Glu Lys Asp Ser 
    530                 535                 540                 


Ile Gln Gln Ser Phe Ser Lys Glu Ala Lys Ala Gln Ala Leu Gln Ala 
545                 550                 555                 560 


Gln Gln Arg Glu Gln Glu Leu Thr Gln Lys Ile Gln Gln Met Glu Ala 
                565                 570                 575     


Gln His Asp Lys Thr Glu Asn Glu Gln Tyr Leu Leu Leu Thr Ser Gln 
            580                 585                 590         


Asn Thr Phe Leu Thr Lys Leu Lys Glu Glu Cys Cys Thr Leu Ala Lys 
        595                 600                 605             


Lys Leu Glu Gln Ile Ser Gln Lys Thr Arg Ser Glu Ile Ala Gln Leu 
    610                 615                 620                 


Ser Gln Glu Lys Arg Tyr Thr Tyr Asp Lys Leu Gly Lys Leu Gln Arg 
625                 630                 635                 640 


Arg Asn Glu Glu Leu Glu Glu Gln Cys Val Gln His Gly Arg Val His 
                645                 650                 655     


Glu Thr Met Lys Gln Arg Leu Arg Gln Leu Asp Lys His Ser Gln Ala 
            660                 665                 670         


Thr Ala Gln Gln Leu Val Gln Leu Leu Ser Lys Gln Asn Gln Leu Leu 
        675                 680                 685             


Leu Glu Arg Gln Ser Leu Ser Glu Glu Val Asp Arg Leu Arg Thr Gln 
    690                 695                 700                 


Leu Pro Ser Met Pro Gln Ser Asp Cys 
705                 710             


<210>  1561
<211>  801
<212>  PRT
<213>  Homo sapiens

<400>  1561

Met His His Arg Met Asn Glu Met Asn Leu Ser Pro Val Gly Met Glu 
1               5                   10                  15      


Gln Leu Thr Ser Ser Ser Val Ser Asn Ala Leu Pro Val Ser Gly Ser 
            20                  25                  30          


His Leu Gly Leu Ala Ala Ser Pro Thr His Ser Ala Ile Pro Ala Pro 
        35                  40                  45              


Gly Leu Pro Val Ala Ile Pro Asn Leu Gly Pro Ser Leu Ser Ser Leu 
    50                  55                  60                  


Pro Ser Ala Leu Ser Leu Met Leu Pro Met Gly Ile Gly Asp Arg Gly 
65                  70                  75                  80  


Val Met Cys Gly Leu Pro Glu Arg Asn Tyr Thr Leu Pro Pro Pro Pro 
                85                  90                  95      


Tyr Pro His Leu Glu Ser Ser Tyr Phe Arg Thr Ile Leu Pro Gly Ile 
            100                 105                 110         


Leu Ser Tyr Leu Ala Asp Arg Pro Pro Pro Gln Tyr Ile His Pro Asn 
        115                 120                 125             


Ser Ile Asn Val Asp Gly Asn Thr Ala Leu Ser Ile Thr Asn Asn Pro 
    130                 135                 140                 


Ser Ala Leu Asp Pro Tyr Gln Ser Asn Gly Asn Val Gly Leu Glu Pro 
145                 150                 155                 160 


Gly Ile Val Ser Ile Asp Ser Arg Ser Val Asn Thr His Gly Ala Gln 
                165                 170                 175     


Ser Leu His Pro Ser Asp Gly His Glu Val Ala Leu Asp Thr Ala Ile 
            180                 185                 190         


Thr Met Glu Asn Val Ser Arg Val Thr Ser Pro Ile Ser Thr Asp Gly 
        195                 200                 205             


Met Ala Glu Glu Leu Thr Met Asp Gly Val Ala Gly Glu His Ser Gln 
    210                 215                 220                 


Ile Pro Asn Gly Ser Arg Ser His Glu Pro Leu Ser Val Asp Ser Val 
225                 230                 235                 240 


Ser Asn Asn Leu Ala Ala Asp Ala Val Gly His Gly Gly Val Ile Pro 
                245                 250                 255     


Met His Gly Asn Gly Leu Glu Leu Pro Val Val Met Glu Thr Asp His 
            260                 265                 270         


Ile Ala Ser Arg Val Asn Gly Met Ser Asp Ser Ala Leu Ser Asp Ser 
        275                 280                 285             


Ile His Thr Val Ala Met Ser Thr Asn Ser Val Ser Val Ala Leu Ser 
    290                 295                 300                 


Thr Ser His Asn Leu Ala Ser Leu Glu Ser Val Ser Leu His Glu Val 
305                 310                 315                 320 


Gly Leu Ser Leu Glu Pro Val Ala Val Ser Ser Ile Thr Gln Glu Val 
                325                 330                 335     


Ala Met Gly Thr Gly His Val Asp Val Ser Ser Asp Ser Leu Ser Phe 
            340                 345                 350         


Val Ser Pro Ser Leu Gln Met Glu Asp Ser Asn Ser Asn Lys Glu Asn 
        355                 360                 365             


Met Ala Thr Leu Phe Thr Ile Trp Cys Thr Leu Cys Asp Arg Ala Tyr 
    370                 375                 380                 


Pro Ser Asp Cys Pro Glu His Gly Pro Val Thr Phe Val Pro Asp Thr 
385                 390                 395                 400 


Pro Ile Glu Ser Arg Ala Arg Leu Ser Leu Pro Lys Gln Leu Val Leu 
                405                 410                 415     


Arg Gln Ser Ile Val Gly Ala Glu Val Gly Val Trp Thr Gly Glu Thr 
            420                 425                 430         


Ile Pro Val Arg Thr Cys Phe Gly Pro Leu Ile Gly Gln Gln Ser His 
        435                 440                 445             


Ser Met Glu Val Ala Glu Trp Thr Asp Lys Ala Val Asn His Ile Trp 
    450                 455                 460                 


Lys Ile Tyr His Asn Gly Val Leu Glu Phe Cys Ile Ile Thr Thr Asp 
465                 470                 475                 480 


Glu Asn Glu Cys Asn Trp Met Met Phe Val Arg Lys Ala Arg Asn Arg 
                485                 490                 495     


Glu Glu Gln Asn Leu Val Ala Tyr Pro His Asp Gly Lys Ile Phe Phe 
            500                 505                 510         


Cys Thr Ser Gln Asp Ile Pro Pro Glu Asn Glu Leu Leu Phe Tyr Tyr 
        515                 520                 525             


Ser Arg Asp Tyr Ala Gln Gln Ile Gly Val Pro Glu His Pro Asp Val 
    530                 535                 540                 


His Leu Cys Asn Cys Gly Lys Glu Cys Asn Ser Tyr Thr Glu Phe Lys 
545                 550                 555                 560 


Ala His Leu Thr Ser His Ile His Asn His Leu Pro Thr Gln Gly His 
                565                 570                 575     


Ser Gly Ser His Gly Pro Ser His Ser Lys Glu Arg Lys Trp Lys Cys 
            580                 585                 590         


Ser Met Cys Pro Gln Ala Phe Ile Ser Pro Ser Lys Leu His Val His 
        595                 600                 605             


Phe Met Gly His Met Gly Met Lys Pro His Lys Cys Asp Phe Cys Ser 
    610                 615                 620                 


Lys Ala Phe Ser Asp Pro Ser Asn Leu Arg Thr His Leu Lys Ile His 
625                 630                 635                 640 


Thr Gly Gln Lys Asn Tyr Arg Cys Thr Leu Cys Asp Lys Ser Phe Thr 
                645                 650                 655     


Gln Lys Ala His Leu Glu Ser His Met Val Ile His Thr Gly Glu Lys 
            660                 665                 670         


Asn Leu Lys Cys Asp Tyr Cys Asp Lys Leu Phe Met Arg Arg Gln Asp 
        675                 680                 685             


Leu Lys Gln His Val Leu Ile His Thr Gln Glu Arg Gln Ile Lys Cys 
    690                 695                 700                 


Pro Lys Cys Asp Lys Leu Phe Leu Arg Thr Asn His Leu Lys Lys His 
705                 710                 715                 720 


Leu Asn Ser His Glu Gly Lys Arg Asp Tyr Val Cys Glu Lys Cys Thr 
                725                 730                 735     


Lys Ala Tyr Leu Thr Lys Tyr His Leu Thr Arg His Leu Lys Thr Cys 
            740                 745                 750         


Lys Gly Pro Thr Ser Ser Ser Ser Ala Pro Glu Glu Glu Glu Glu Asp 
        755                 760                 765             


Asp Ser Glu Glu Glu Asp Leu Ala Asp Ser Val Gly Thr Glu Asp Cys 
    770                 775                 780                 


Arg Ile Asn Ser Ala Val Tyr Ser Ala Asp Glu Ser Leu Ser Ala His 
785                 790                 795                 800 


Lys 
    


<210>  1562
<211>  1078
<212>  PRT
<213>  Homo sapiens

<400>  1562

Met Ala Pro Arg Lys Arg Gly Gly Arg Gly Ile Ser Phe Ile Phe Cys 
1               5                   10                  15      


Cys Phe Arg Asn Asn Asp His Pro Glu Ile Thr Tyr Arg Leu Arg Asn 
            20                  25                  30          


Asp Ser Asn Phe Ala Leu Gln Thr Met Glu Pro Ala Leu Pro Met Pro 
        35                  40                  45              


Pro Val Glu Glu Leu Asp Val Met Phe Ser Glu Leu Val Asp Glu Leu 
    50                  55                  60                  


Asp Leu Thr Asp Lys His Arg Glu Ala Met Phe Ala Leu Pro Ala Glu 
65                  70                  75                  80  


Lys Lys Trp Gln Ile Tyr Cys Ser Lys Lys Lys Asp Gln Glu Glu Asn 
                85                  90                  95      


Lys Gly Ala Thr Ser Trp Pro Glu Phe Tyr Ile Asp Gln Leu Asn Ser 
            100                 105                 110         


Met Ala Ala Arg Lys Ser Leu Leu Ala Leu Glu Lys Glu Glu Glu Glu 
        115                 120                 125             


Glu Arg Ser Lys Thr Ile Glu Ser Leu Lys Thr Ala Leu Arg Thr Lys 
    130                 135                 140                 


Pro Met Arg Phe Val Thr Arg Phe Ile Asp Leu Asp Gly Leu Ser Cys 
145                 150                 155                 160 


Ile Leu Asn Phe Leu Lys Thr Met Asp Tyr Glu Thr Ser Glu Ser Arg 
                165                 170                 175     


Ile His Thr Ser Leu Ile Gly Cys Ile Lys Ala Leu Met Asn Asn Ser 
            180                 185                 190         


Gln Gly Arg Ala His Val Leu Ala His Ser Glu Ser Ile Asn Val Ile 
        195                 200                 205             


Ala Gln Ser Leu Ser Thr Glu Asn Ile Lys Thr Lys Val Ala Val Leu 
    210                 215                 220                 


Glu Ile Leu Gly Ala Val Cys Leu Val Pro Gly Gly His Lys Lys Val 
225                 230                 235                 240 


Leu Gln Ala Met Leu His Tyr Gln Lys Tyr Ala Ser Glu Arg Thr Arg 
                245                 250                 255     


Phe Gln Thr Leu Ile Asn Asp Leu Asp Lys Ser Thr Gly Arg Tyr Arg 
            260                 265                 270         


Asp Glu Val Ser Leu Lys Thr Ala Ile Met Ser Phe Ile Asn Ala Val 
        275                 280                 285             


Leu Ser Gln Gly Ala Gly Val Glu Ser Leu Asp Phe Arg Leu His Leu 
    290                 295                 300                 


Arg Tyr Glu Phe Leu Met Leu Gly Ile Gln Pro Val Ile Asp Lys Leu 
305                 310                 315                 320 


Arg Glu His Glu Asn Ser Thr Leu Asp Arg His Leu Asp Phe Phe Glu 
                325                 330                 335     


Met Leu Arg Asn Glu Asp Glu Leu Glu Phe Ala Lys Arg Phe Glu Leu 
            340                 345                 350         


Val His Ile Asp Thr Lys Ser Ala Thr Gln Met Phe Glu Leu Thr Arg 
        355                 360                 365             


Lys Arg Leu Thr His Ser Glu Ala Tyr Pro His Phe Met Ser Ile Leu 
    370                 375                 380                 


His His Cys Leu Gln Met Pro Tyr Lys Arg Ser Gly Asn Thr Val Gln 
385                 390                 395                 400 


Tyr Trp Leu Leu Leu Asp Arg Ile Ile Gln Gln Ile Val Ile Gln Asn 
                405                 410                 415     


Asp Lys Gly Gln Asp Pro Asp Ser Thr Pro Leu Glu Asn Phe Asn Ile 
            420                 425                 430         


Lys Asn Val Val Arg Met Leu Val Asn Glu Asn Glu Val Lys Gln Trp 
        435                 440                 445             


Lys Glu Gln Ala Glu Lys Met Arg Lys Glu His Asn Glu Leu Gln Gln 
    450                 455                 460                 


Lys Leu Glu Lys Lys Glu Arg Glu Cys Asp Ala Lys Thr Gln Glu Lys 
465                 470                 475                 480 


Glu Glu Met Met Gln Thr Leu Asn Lys Met Lys Glu Lys Leu Glu Lys 
                485                 490                 495     


Glu Thr Thr Glu His Lys Gln Val Lys Gln Gln Val Ala Asp Leu Thr 
            500                 505                 510         


Ala Gln Leu His Glu Leu Ser Arg Arg Ala Val Cys Ala Ser Ile Pro 
        515                 520                 525             


Gly Gly Pro Ser Pro Gly Ala Pro Gly Gly Pro Phe Pro Ser Ser Val 
    530                 535                 540                 


Pro Gly Ser Leu Leu Pro Pro Pro Pro Pro Pro Pro Leu Pro Gly Gly 
545                 550                 555                 560 


Met Leu Pro Pro Pro Pro Pro Pro Leu Pro Pro Gly Gly Pro Pro Pro 
                565                 570                 575     


Pro Pro Gly Pro Pro Pro Leu Gly Ala Ile Met Pro Pro Pro Gly Ala 
            580                 585                 590         


Pro Met Gly Leu Ala Leu Lys Lys Lys Ser Ile Pro Gln Pro Thr Asn 
        595                 600                 605             


Ala Leu Lys Ser Phe Asn Trp Ser Lys Leu Pro Glu Asn Lys Leu Glu 
    610                 615                 620                 


Gly Thr Val Trp Thr Glu Ile Asp Asp Thr Lys Val Phe Lys Ile Leu 
625                 630                 635                 640 


Asp Leu Glu Asp Leu Glu Arg Thr Phe Ser Ala Tyr Gln Arg Gln Gln 
                645                 650                 655     


Asp Phe Phe Val Asn Ser Asn Ser Lys Gln Lys Glu Ala Asp Ala Ile 
            660                 665                 670         


Asp Asp Thr Leu Ser Ser Lys Leu Lys Val Lys Glu Leu Ser Val Ile 
        675                 680                 685             


Asp Gly Arg Arg Ala Gln Asn Cys Asn Ile Leu Leu Ser Arg Leu Lys 
    690                 695                 700                 


Leu Ser Asn Asp Glu Ile Lys Arg Ala Ile Leu Thr Met Asp Glu Gln 
705                 710                 715                 720 


Glu Asp Leu Pro Lys Asp Met Leu Glu Gln Leu Leu Lys Phe Val Pro 
                725                 730                 735     


Glu Lys Ser Asp Ile Asp Leu Leu Glu Glu His Lys His Glu Leu Asp 
            740                 745                 750         


Arg Met Ala Lys Ala Asp Arg Phe Leu Phe Glu Met Ser Arg Ile Asn 
        755                 760                 765             


His Tyr Gln Gln Arg Leu Gln Ser Leu Tyr Phe Lys Lys Lys Phe Ala 
    770                 775                 780                 


Glu Arg Val Ala Glu Val Lys Pro Lys Val Glu Ala Ile Arg Ser Gly 
785                 790                 795                 800 


Ser Glu Glu Val Phe Arg Ser Gly Ala Leu Lys Gln Leu Leu Glu Val 
                805                 810                 815     


Val Leu Ala Phe Gly Asn Tyr Met Asn Lys Gly Gln Arg Gly Asn Ala 
            820                 825                 830         


Tyr Gly Phe Lys Ile Ser Ser Leu Asn Lys Ile Ala Asp Thr Lys Ser 
        835                 840                 845             


Ser Ile Asp Lys Asn Ile Thr Leu Leu His Tyr Leu Ile Thr Ile Val 
    850                 855                 860                 


Glu Asn Lys Tyr Pro Ser Val Leu Asn Leu Asn Glu Glu Leu Arg Asp 
865                 870                 875                 880 


Ile Pro Gln Ala Ala Lys Val Asn Met Thr Glu Leu Asp Lys Glu Ile 
                885                 890                 895     


Ser Thr Leu Arg Ser Gly Leu Lys Ala Val Glu Thr Glu Leu Glu Tyr 
            900                 905                 910         


Gln Lys Ser Gln Pro Pro Gln Pro Gly Asp Lys Phe Val Ser Val Val 
        915                 920                 925             


Ser Gln Phe Ile Thr Val Ala Ser Phe Ser Phe Ser Asp Val Glu Asp 
    930                 935                 940                 


Leu Leu Ala Glu Ala Lys Asp Leu Phe Thr Lys Ala Val Lys His Phe 
945                 950                 955                 960 


Gly Glu Glu Ala Gly Lys Ile Gln Pro Asp Glu Phe Phe Gly Ile Phe 
                965                 970                 975     


Asp Gln Phe Leu Gln Ala Val Ser Glu Ala Lys Gln Glu Asn Glu Asn 
            980                 985                 990         


Met Arg Lys Lys Lys Glu Glu Glu  Glu Arg Arg Ala Arg  Met Glu Ala 
        995                 1000                 1005             


Gln Leu  Lys Glu Gln Arg Glu  Arg Glu Arg Lys Met  Arg Lys Ala 
    1010                 1015                 1020             


Lys Glu  Asn Ser Glu Glu Ser  Gly Glu Phe Asp Asp  Leu Val Ser 
    1025                 1030                 1035             


Ala Leu  Arg Ser Gly Glu Val  Phe Asp Lys Asp Leu  Ser Lys Leu 
    1040                 1045                 1050             


Lys Arg  Asn Arg Lys Arg Ile  Thr Asn Gln Met Thr  Asp Ser Ser 
    1055                 1060                 1065             


Arg Glu  Arg Pro Ile Thr Lys  Leu Asn Phe 
    1070                 1075             


<210>  1563
<211>  678
<212>  PRT
<213>  Homo sapiens

<400>  1563

Met Pro Thr Trp Gly Ala Arg Pro Ala Ser Pro Asp Arg Phe Ala Val 
1               5                   10                  15      


Ser Ala Glu Ala Glu Asn Lys Val Arg Glu Gln Gln Pro His Val Glu 
            20                  25                  30          


Arg Ile Phe Ser Val Gly Val Ser Val Leu Pro Lys Asp Cys Pro Asp 
        35                  40                  45              


Asn Pro His Ile Trp Leu Gln Leu Glu Gly Pro Lys Glu Asn Ala Ser 
    50                  55                  60                  


Arg Ala Lys Glu Tyr Leu Lys Gly Leu Cys Ser Pro Glu Leu Gln Asp 
65                  70                  75                  80  


Glu Ile His Tyr Pro Pro Lys Leu His Cys Ile Phe Leu Gly Ala Gln 
                85                  90                  95      


Gly Phe Phe Leu Asp Cys Leu Ala Trp Ser Thr Ser Ala His Leu Val 
            100                 105                 110         


Pro Arg Ala Pro Gly Ser Leu Met Ile Ser Gly Leu Thr Glu Ala Phe 
        115                 120                 125             


Val Met Ala Gln Ser Arg Val Glu Glu Leu Ala Glu Arg Leu Ser Trp 
    130                 135                 140                 


Asp Phe Thr Pro Gly Pro Ser Ser Gly Ala Ser Gln Cys Thr Gly Val 
145                 150                 155                 160 


Leu Arg Asp Phe Ser Ala Leu Leu Gln Ser Pro Gly Asp Ala His Arg 
                165                 170                 175     


Glu Ala Leu Leu Gln Leu Pro Leu Ala Val Gln Glu Glu Leu Leu Ser 
            180                 185                 190         


Leu Val Gln Glu Ala Ser Ser Gly Gln Gly Pro Gly Ala Leu Ala Ser 
        195                 200                 205             


Trp Glu Gly Arg Ser Ser Ala Leu Leu Gly Ala Gln Cys Gln Gly Val 
    210                 215                 220                 


Arg Ala Pro Pro Ser Asp Gly Arg Glu Ser Leu Asp Thr Gly Ser Met 
225                 230                 235                 240 


Gly Pro Gly Asp Cys Arg Gly Ala Arg Gly Asp Thr Tyr Ala Val Glu 
                245                 250                 255     


Lys Glu Gly Gly Lys Gln Gly Gly Pro Arg Glu Met Asp Trp Gly Trp 
            260                 265                 270         


Lys Glu Leu Pro Gly Glu Glu Ala Trp Glu Arg Glu Val Ala Leu Arg 
        275                 280                 285             


Pro Gln Ser Val Gly Gly Gly Ala Arg Glu Ser Ala Pro Leu Lys Gly 
    290                 295                 300                 


Lys Ala Leu Gly Lys Glu Glu Ile Ala Leu Gly Gly Gly Gly Phe Cys 
305                 310                 315                 320 


Val His Arg Glu Pro Pro Gly Ala His Gly Ser Cys His Arg Ala Ala 
                325                 330                 335     


Gln Ser Arg Gly Ala Ser Leu Leu Gln Arg Leu His Asn Gly Asn Ala 
            340                 345                 350         


Ser Pro Pro Arg Val Pro Ser Pro Pro Pro Ala Pro Glu Pro Pro Trp 
        355                 360                 365             


His Cys Gly Asp Arg Gly Asp Cys Gly Asp Arg Gly Asp Val Gly Asp 
    370                 375                 380                 


Arg Gly Asp Lys Gln Gln Gly Met Ala Arg Gly Arg Gly Pro Gln Trp 
385                 390                 395                 400 


Lys Arg Gly Ala Arg Gly Gly Asn Leu Val Thr Gly Thr Gln Arg Phe 
                405                 410                 415     


Lys Glu Ala Leu Gln Asp Pro Phe Thr Leu Cys Leu Ala Asn Val Pro 
            420                 425                 430         


Gly Gln Pro Asp Leu Arg His Ile Val Ile Asp Gly Ser Asn Val Ala 
        435                 440                 445             


Met Val His Gly Leu Gln His Tyr Phe Ser Ser Arg Gly Ile Ala Ile 
    450                 455                 460                 


Ala Val Gln Tyr Phe Trp Asp Arg Gly His Arg Asp Ile Thr Val Phe 
465                 470                 475                 480 


Val Pro Gln Trp Arg Phe Ser Lys Asp Ala Lys Val Arg Glu Ser His 
                485                 490                 495     


Phe Leu Gln Lys Leu Tyr Ser Leu Ser Leu Leu Ser Leu Thr Pro Ser 
            500                 505                 510         


Arg Val Met Asp Gly Lys Arg Ile Ser Ser Tyr Asp Asp Arg Phe Met 
        515                 520                 525             


Val Lys Leu Ala Glu Glu Thr Asp Gly Ile Ile Val Ser Asn Asp Gln 
    530                 535                 540                 


Phe Arg Asp Leu Ala Glu Glu Ser Glu Lys Trp Met Ala Ile Ile Arg 
545                 550                 555                 560 


Glu Arg Leu Leu Pro Phe Thr Phe Val Gly Asn Leu Phe Met Val Pro 
                565                 570                 575     


Asp Asp Pro Leu Gly Arg Asn Gly Pro Thr Leu Asp Glu Phe Leu Lys 
            580                 585                 590         


Lys Pro Ala Arg Thr Gln Gly Ser Ser Lys Ala Gln His Pro Ser Arg 
        595                 600                 605             


Gly Phe Ala Glu His Gly Lys Gln Gln Gln Gly Arg Glu Glu Glu Lys 
    610                 615                 620                 


Gly Ser Gly Gly Ile Arg Lys Thr Arg Glu Thr Glu Arg Leu Arg Arg 
625                 630                 635                 640 


Gln Leu Leu Glu Val Phe Trp Gly Gln Asp His Lys Val Asp Phe Ile 
                645                 650                 655     


Leu Gln Arg Glu Pro Tyr Cys Arg Asp Ile Asn Gln Leu Ser Glu Ala 
            660                 665                 670         


Leu Leu Ser Leu Asn Phe 
        675             


<210>  1564
<211>  147
<212>  PRT
<213>  Homo sapiens

<400>  1564

Met Ser Ser Glu Pro Pro Pro Pro Pro Gln Pro Pro Thr His Gln Ala 
1               5                   10                  15      


Ser Val Gly Leu Leu Asp Thr Pro Arg Ser Arg Glu Arg Ser Pro Ser 
            20                  25                  30          


Pro Leu Arg Gly Asn Val Val Pro Ser Pro Leu Pro Thr Arg Arg Thr 
        35                  40                  45              


Arg Thr Phe Ser Ala Thr Val Arg Ala Ser Gln Gly Pro Val Tyr Lys 
    50                  55                  60                  


Gly Val Cys Lys Cys Phe Cys Arg Ser Lys Gly His Gly Phe Ile Thr 
65                  70                  75                  80  


Pro Ala Asp Gly Gly Pro Asp Ile Phe Leu His Ile Ser Asp Val Glu 
                85                  90                  95      


Gly Glu Tyr Val Pro Val Glu Gly Asp Glu Val Thr Tyr Lys Met Cys 
            100                 105                 110         


Ser Ile Pro Pro Lys Asn Glu Lys Leu Gln Ala Val Glu Val Val Ile 
        115                 120                 125             


Thr His Leu Ala Pro Gly Thr Lys His Glu Thr Trp Ser Gly His Val 
    130                 135                 140                 


Ile Ser Ser 
145         


<210>  1565
<211>  636
<212>  PRT
<213>  Homo sapiens

<400>  1565

Met Asn Pro Ser Ala Pro Ser Tyr Pro Met Ala Ser Leu Tyr Val Gly 
1               5                   10                  15      


Asp Leu His Pro Asp Val Thr Glu Ala Met Leu Tyr Glu Lys Phe Ser 
            20                  25                  30          


Pro Ala Gly Pro Ile Leu Ser Ile Arg Val Cys Arg Asp Met Ile Thr 
        35                  40                  45              


Arg Arg Ser Leu Gly Tyr Ala Tyr Val Asn Phe Gln Gln Pro Ala Asp 
    50                  55                  60                  


Ala Glu Arg Ala Leu Asp Thr Met Asn Phe Asp Val Ile Lys Gly Lys 
65                  70                  75                  80  


Pro Val Arg Ile Met Trp Ser Gln Arg Asp Pro Ser Leu Arg Lys Ser 
                85                  90                  95      


Gly Val Gly Asn Ile Phe Ile Lys Asn Leu Asp Lys Ser Ile Asp Asn 
            100                 105                 110         


Lys Ala Leu Tyr Asp Thr Phe Ser Ala Phe Gly Asn Ile Leu Ser Cys 
        115                 120                 125             


Lys Val Val Cys Asp Glu Asn Gly Ser Lys Gly Tyr Gly Phe Val His 
    130                 135                 140                 


Phe Glu Thr Gln Glu Ala Ala Glu Arg Ala Ile Glu Lys Met Asn Gly 
145                 150                 155                 160 


Met Leu Leu Asn Asp Arg Lys Val Phe Val Gly Arg Phe Lys Ser Arg 
                165                 170                 175     


Lys Glu Arg Glu Ala Glu Leu Gly Ala Arg Ala Lys Glu Phe Thr Asn 
            180                 185                 190         


Val Tyr Ile Lys Asn Phe Gly Glu Asp Met Asp Asp Glu Arg Leu Lys 
        195                 200                 205             


Asp Leu Phe Gly Lys Phe Gly Pro Ala Leu Ser Val Lys Val Met Thr 
    210                 215                 220                 


Asp Glu Ser Gly Lys Ser Lys Gly Phe Gly Phe Val Ser Phe Glu Arg 
225                 230                 235                 240 


His Glu Asp Ala Gln Lys Ala Val Asp Glu Met Asn Gly Lys Glu Leu 
                245                 250                 255     


Asn Gly Lys Gln Ile Tyr Val Gly Arg Ala Gln Lys Lys Val Glu Arg 
            260                 265                 270         


Gln Thr Glu Leu Lys Arg Lys Phe Glu Gln Met Lys Gln Asp Arg Ile 
        275                 280                 285             


Thr Arg Tyr Gln Gly Val Asn Leu Tyr Val Lys Asn Leu Asp Asp Gly 
    290                 295                 300                 


Ile Asp Asp Glu Arg Leu Arg Lys Glu Phe Ser Pro Phe Gly Thr Ile 
305                 310                 315                 320 


Thr Ser Ala Lys Val Met Met Glu Gly Gly Arg Ser Lys Gly Phe Gly 
                325                 330                 335     


Phe Val Cys Phe Ser Ser Pro Glu Glu Ala Thr Lys Ala Val Thr Glu 
            340                 345                 350         


Met Asn Gly Arg Ile Val Ala Thr Lys Pro Leu Tyr Val Ala Leu Ala 
        355                 360                 365             


Gln Arg Lys Glu Glu Arg Gln Ala His Leu Thr Asn Gln Tyr Met Gln 
    370                 375                 380                 


Arg Met Ala Ser Val Arg Ala Val Pro Asn Pro Val Ile Asn Pro Tyr 
385                 390                 395                 400 


Gln Pro Ala Pro Pro Ser Gly Tyr Phe Met Ala Ala Ile Pro Gln Thr 
                405                 410                 415     


Gln Asn Arg Ala Ala Tyr Tyr Pro Pro Ser Gln Ile Ala Gln Leu Arg 
            420                 425                 430         


Pro Ser Pro Arg Trp Thr Ala Gln Gly Ala Arg Pro His Pro Phe Gln 
        435                 440                 445             


Asn Met Pro Gly Ala Ile Arg Pro Ala Ala Pro Arg Pro Pro Phe Ser 
    450                 455                 460                 


Thr Met Arg Pro Ala Ser Ser Gln Val Pro Arg Val Met Ser Thr Gln 
465                 470                 475                 480 


Arg Val Ala Asn Thr Ser Thr Gln Thr Met Gly Pro Arg Pro Ala Ala 
                485                 490                 495     


Ala Ala Ala Ala Ala Thr Pro Ala Val Arg Thr Val Pro Gln Tyr Lys 
            500                 505                 510         


Tyr Ala Ala Gly Val Arg Asn Pro Gln Gln His Leu Asn Ala Gln Pro 
        515                 520                 525             


Gln Val Thr Met Gln Gln Pro Ala Val His Val Gln Gly Gln Glu Pro 
    530                 535                 540                 


Leu Thr Ala Ser Met Leu Ala Ser Ala Pro Pro Gln Glu Gln Lys Gln 
545                 550                 555                 560 


Met Leu Gly Glu Arg Leu Phe Pro Leu Ile Gln Ala Met His Pro Thr 
                565                 570                 575     


Leu Ala Gly Lys Ile Thr Gly Met Leu Leu Glu Ile Asp Asn Ser Glu 
            580                 585                 590         


Leu Leu His Met Leu Glu Ser Pro Glu Ser Leu Arg Ser Lys Val Asp 
        595                 600                 605             


Glu Ala Val Ala Val Leu Gln Ala His Gln Ala Lys Glu Ala Ala Gln 
    610                 615                 620                 


Lys Ala Val Asn Ser Ala Thr Gly Val Pro Thr Val 
625                 630                 635     


<210>  1566
<211>  829
<212>  PRT
<213>  Homo sapiens

<400>  1566

Met Ala Glu Ala Glu Glu Gln Glu Thr Gly Ser Leu Glu Glu Ser Thr 
1               5                   10                  15      


Asp Glu Ser Glu Glu Glu Glu Ser Glu Glu Glu Pro Lys Leu Lys Tyr 
            20                  25                  30          


Glu Arg Leu Ser Asn Gly Val Thr Glu Ile Leu Gln Lys Asp Ala Ala 
        35                  40                  45              


Ser Cys Met Thr Val His Asp Lys Phe Leu Ala Leu Gly Thr His Tyr 
    50                  55                  60                  


Gly Lys Val Tyr Leu Leu Asp Val Gln Gly Asn Ile Thr Gln Lys Phe 
65                  70                  75                  80  


Asp Val Val Gln Val Phe Gly Leu Tyr Ser Gly Glu Glu Phe His Glu 
                85                  90                  95      


Thr Phe Asp Cys Pro Ile Lys Ile Ile Ala Val His Pro His Phe Val 
            100                 105                 110         


Arg Ser Ser Cys Lys Gln Phe Val Thr Gly Gly Lys Lys Leu Leu Leu 
        115                 120                 125             


Phe Glu Arg Ser Trp Met Asn Arg Trp Lys Ser Ala Val Leu His Glu 
    130                 135                 140                 


Gly Glu Gly Asn Ile Arg Ser Val Lys Trp Arg Gly His Leu Ile Ala 
145                 150                 155                 160 


Trp Ala Asn Asn Met Gly Val Lys Ile Phe Asp Ile Ile Ser Lys Gln 
                165                 170                 175     


Arg Ile Thr Asn Val Pro Arg Asp Asp Ile Ser Leu Arg Pro Asp Met 
            180                 185                 190         


Tyr Pro Cys Ser Leu Cys Trp Lys Asp Asn Val Thr Leu Ile Ile Gly 
        195                 200                 205             


Trp Gly Thr Ser Val Lys Val Cys Ser Val Lys Glu Arg His Ala Ser 
    210                 215                 220                 


Glu Met Arg Asp Leu Pro Ser Arg Tyr Val Glu Ile Val Ser Gln Phe 
225                 230                 235                 240 


Glu Thr Glu Phe Tyr Ile Ser Gly Leu Ala Pro Leu Cys Asp Gln Leu 
                245                 250                 255     


Val Val Leu Ser Tyr Val Lys Glu Ile Ser Glu Lys Thr Glu Arg Glu 
            260                 265                 270         


Tyr Cys Ala Arg Pro Arg Leu Asp Ile Ile Gln Pro Leu Ser Glu Thr 
        275                 280                 285             


Cys Glu Glu Ile Ser Ser Asp Ala Leu Thr Val Arg Gly Phe Gln Glu 
    290                 295                 300                 


Asn Glu Cys Arg Asp Tyr His Leu Glu Tyr Ser Glu Gly Glu Ser Leu 
305                 310                 315                 320 


Phe Tyr Ile Val Ser Pro Arg Asp Val Val Val Ala Lys Glu Arg Asp 
                325                 330                 335     


Gln Asp Asp His Ile Asp Trp Leu Leu Glu Lys Lys Lys Tyr Glu Glu 
            340                 345                 350         


Ala Leu Met Ala Ala Glu Ile Ser Gln Lys Asn Ile Lys Arg His Lys 
        355                 360                 365             


Ile Leu Asp Ile Gly Leu Ala Tyr Ile Asn His Leu Val Glu Arg Gly 
    370                 375                 380                 


Asp Tyr Asp Ile Ala Ala Arg Lys Cys Gln Lys Ile Leu Gly Lys Asn 
385                 390                 395                 400 


Ala Ala Leu Trp Glu Tyr Glu Val Tyr Lys Phe Lys Glu Ile Gly Gln 
                405                 410                 415     


Leu Lys Ala Ile Ser Pro Tyr Leu Pro Arg Gly Asp Pro Val Leu Lys 
            420                 425                 430         


Pro Leu Ile Tyr Glu Met Ile Leu His Glu Phe Leu Glu Ser Asp Tyr 
        435                 440                 445             


Glu Gly Phe Ala Thr Leu Ile Arg Glu Trp Pro Gly Asp Leu Tyr Asn 
    450                 455                 460                 


Asn Ser Val Ile Val Gln Ala Val Arg Asp His Leu Lys Lys Asp Ser 
465                 470                 475                 480 


Gln Asn Lys Thr Leu Leu Lys Thr Leu Ala Glu Leu Tyr Thr Tyr Asp 
                485                 490                 495     


Lys Asn Tyr Gly Asn Ala Leu Glu Ile Tyr Leu Thr Leu Arg His Lys 
            500                 505                 510         


Asp Val Phe Gln Leu Ile His Lys His Asn Leu Phe Ser Ser Ile Lys 
        515                 520                 525             


Asp Lys Ile Val Leu Leu Met Asp Phe Asp Ser Glu Lys Ala Val Asp 
    530                 535                 540                 


Met Leu Leu Asp Asn Glu Asp Lys Ile Ser Ile Lys Lys Val Val Glu 
545                 550                 555                 560 


Glu Leu Glu Asp Arg Pro Glu Leu Gln His Val Tyr Leu His Lys Leu 
                565                 570                 575     


Phe Lys Arg Asp His His Lys Gly Gln Arg Tyr His Glu Lys Gln Ile 
            580                 585                 590         


Ser Leu Tyr Ala Glu Tyr Asp Arg Pro Asn Leu Leu Pro Phe Leu Arg 
        595                 600                 605             


Asp Ser Thr His Cys Pro Leu Glu Lys Ala Leu Glu Ile Cys Gln Gln 
    610                 615                 620                 


Arg Asn Phe Val Glu Glu Thr Val Tyr Leu Leu Ser Arg Met Gly Asn 
625                 630                 635                 640 


Ser Arg Ser Ala Leu Lys Met Ile Met Glu Glu Leu His Asp Val Asp 
                645                 650                 655     


Lys Ala Ile Glu Phe Ala Lys Glu Gln Asp Asp Gly Glu Leu Trp Glu 
            660                 665                 670         


Asp Leu Ile Leu Tyr Ser Ile Asp Lys Pro Pro Phe Ile Thr Gly Leu 
        675                 680                 685             


Leu Asn Asn Ile Gly Thr His Val Asp Pro Ile Leu Leu Ile His Arg 
    690                 695                 700                 


Ile Lys Glu Gly Met Glu Ile Pro Asn Leu Arg Asp Ser Leu Val Lys 
705                 710                 715                 720 


Ile Leu Gln Asp Tyr Asn Leu Gln Ile Leu Leu Arg Glu Gly Cys Lys 
                725                 730                 735     


Lys Ile Leu Val Ala Asp Ser Leu Ser Leu Leu Lys Lys Met His Arg 
            740                 745                 750         


Thr Gln Met Lys Gly Val Leu Val Asp Glu Glu Asn Ile Cys Glu Ser 
        755                 760                 765             


Cys Leu Ser Pro Ile Leu Pro Ser Asp Ala Ala Lys Pro Phe Ser Val 
    770                 775                 780                 


Val Val Phe His Cys Arg His Met Phe His Lys Glu Cys Leu Pro Met 
785                 790                 795                 800 


Pro Ser Met Asn Ser Ala Ala Gln Phe Cys Asn Ile Cys Ser Ala Lys 
                805                 810                 815     


Asn Arg Gly Pro Gly Ser Ala Ile Leu Glu Met Lys Lys 
            820                 825                 


<210>  1567
<211>  756
<212>  PRT
<213>  Homo sapiens

<400>  1567

Met Val Val Thr Arg Ser Ala Arg Ala Lys Ala Ser Ile Gln Ala Ala 
1               5                   10                  15      


Ser Ala Glu Ser Ser Gly Gln Lys Ser Phe Ala Ala Asn Gly Ile Gln 
            20                  25                  30          


Ala His Pro Glu Ser Ser Thr Gly Ser Asp Ala Arg Thr Thr Ala Glu 
        35                  40                  45              


Ser Gln Thr Thr Gly Lys Gln Ser Leu Ile Pro Arg Thr Pro Lys Ala 
    50                  55                  60                  


Arg Lys Arg Lys Ser Arg Thr Thr Gly Ser Leu Pro Lys Gly Thr Glu 
65                  70                  75                  80  


Pro Ser Thr Asp Gly Glu Thr Ser Glu Ala Glu Ser Asn Tyr Ser Val 
                85                  90                  95      


Ser Glu His His Asp Thr Ile Leu Arg Val Thr Arg Arg Arg Gln Ile 
            100                 105                 110         


Leu Ile Ala Cys Ser Pro Val Ser Ser Val Arg Lys Lys Pro Lys Val 
        115                 120                 125             


Thr Pro Thr Lys Glu Ser Tyr Thr Glu Glu Ile Val Ser Glu Ala Glu 
    130                 135                 140                 


Ser His Val Ser Gly Ile Ser Arg Ile Val Leu Pro Thr Glu Lys Thr 
145                 150                 155                 160 


Thr Gly Ala Arg Arg Ser Lys Ala Lys Ser Leu Thr Asp Pro Ser Gln 
                165                 170                 175     


Glu Ser His Thr Glu Ala Ile Ser Asp Ala Glu Thr Ser Ser Ser Asp 
            180                 185                 190         


Ile Ser Phe Ser Gly Ile Ala Thr Arg Arg Thr Arg Ser Met Gln Arg 
        195                 200                 205             


Lys Leu Lys Ala Gln Thr Glu Lys Lys Asp Ser Lys Ile Val Pro Gly 
    210                 215                 220                 


Asn Glu Lys Gln Ile Val Gly Thr Pro Val Asn Ser Glu Asp Ser Asp 
225                 230                 235                 240 


Thr Arg Gln Thr Ser His Leu Gln Ala Arg Ser Leu Ser Glu Ile Asn 
                245                 250                 255     


Lys Pro Asn Phe Tyr Asn Asn Asp Phe Asp Asp Asp Phe Ser His Arg 
            260                 265                 270         


Ser Ser Glu Asn Ile Leu Thr Val His Glu Gln Ala Asn Val Glu Ser 
        275                 280                 285             


Leu Lys Glu Thr Lys Gln Asn Cys Lys Asp Leu Asp Glu Asp Ala Asn 
    290                 295                 300                 


Gly Ile Thr Asp Glu Gly Lys Glu Ile Asn Glu Lys Ser Ser Gln Leu 
305                 310                 315                 320 


Lys Asn Leu Ser Glu Leu Gln Asp Thr Ser Leu Gln Gln Leu Val Ser 
                325                 330                 335     


Gln Arg His Ser Thr Pro Gln Asn Lys Asn Ala Val Ser Val His Ser 
            340                 345                 350         


Asn Leu Asn Ser Glu Ala Val Met Lys Ser Leu Thr Gln Thr Phe Ala 
        355                 360                 365             


Thr Val Glu Val Gly Arg Trp Asn Asn Asn Lys Lys Ser Pro Ile Lys 
    370                 375                 380                 


Ala Ser Asp Leu Thr Lys Phe Gly Asp Cys Gly Gly Ser Asp Asp Glu 
385                 390                 395                 400 


Glu Glu Ser Thr Val Ile Ser Val Ser Glu Asp Met Asn Ser Glu Gly 
                405                 410                 415     


Asn Val Asp Phe Glu Cys Asp Thr Lys Leu Tyr Thr Ser Ala Pro Asn 
            420                 425                 430         


Thr Ser Gln Gly Lys Asp Asn Ser Val Leu Leu Val Leu Ser Ser Asp 
        435                 440                 445             


Glu Ser Gln Gln Ser Glu Asn Ser Glu Asn Glu Glu Asp Thr Leu Cys 
    450                 455                 460                 


Phe Val Glu Asn Ser Gly Gln Arg Glu Ser Leu Ser Gly Asp Thr Gly 
465                 470                 475                 480 


Ser Leu Ser Cys Asp Asn Ala Leu Phe Val Ile Asp Thr Thr Pro Gly 
                485                 490                 495     


Met Ser Ala Asp Lys Asn Phe Tyr Leu Glu Glu Glu Asp Lys Ala Ser 
            500                 505                 510         


Glu Val Ala Ile Glu Glu Glu Lys Glu Glu Glu Glu Asp Glu Lys Ser 
        515                 520                 525             


Glu Glu Asp Ser Ser Asp His Asp Glu Asn Glu Asp Glu Phe Ser Asp 
    530                 535                 540                 


Glu Glu Asp Phe Leu Asn Ser Thr Lys Ala Lys Leu Leu Lys Leu Thr 
545                 550                 555                 560 


Ser Ser Ser Ile Asp Pro Gly Leu Ser Ile Lys Gln Leu Gly Gly Leu 
                565                 570                 575     


Tyr Ile Asn Phe Asn Ala Asp Lys Leu Gln Ser Asn Lys Arg Thr Leu 
            580                 585                 590         


Thr Gln Ile Lys Glu Lys Lys Lys Asn Glu Leu Leu Gln Lys Ala Val 
        595                 600                 605             


Ile Thr Pro Asp Phe Glu Lys Asn His Cys Val Pro Pro Tyr Ser Glu 
    610                 615                 620                 


Ser Lys Tyr Gln Leu Gln Lys Lys Arg Arg Lys Glu Arg Gln Lys Thr 
625                 630                 635                 640 


Ala Gly Asp Gly Trp Phe Gly Met Lys Ala Pro Glu Met Thr Asn Glu 
                645                 650                 655     


Leu Lys Asn Asp Leu Lys Ala Leu Lys Met Arg Ala Ser Met Asp Pro 
            660                 665                 670         


Lys Arg Phe Tyr Lys Lys Asn Asp Arg Asp Gly Phe Pro Lys Tyr Phe 
        675                 680                 685             


Gln Ile Gly Thr Ile Val Asp Asn Pro Ala Asp Phe Tyr His Ser Arg 
    690                 695                 700                 


Ile Pro Lys Lys Gln Arg Lys Arg Thr Ile Val Glu Glu Leu Leu Ala 
705                 710                 715                 720 


Asp Ser Glu Phe Arg Arg Tyr Asn Arg Arg Lys Tyr Ser Glu Ile Met 
                725                 730                 735     


Ala Glu Lys Ala Ala Asn Ala Ala Gly Lys Lys Phe Arg Lys Lys Lys 
            740                 745                 750         


Lys Phe Arg Asn 
        755     


<210>  1568
<211>  386
<212>  PRT
<213>  Homo sapiens

<400>  1568

Met Asp Arg Phe Val Trp Thr Ser Gly Leu Leu Glu Ile Asn Glu Thr 
1               5                   10                  15      


Leu Val Ile Gln Gln Arg Gly Val Arg Ile Tyr Asp Gly Glu Glu Lys 
            20                  25                  30          


Ile Lys Phe Asp Ala Gly Thr Leu Leu Leu Ser Thr His Arg Leu Ile 
        35                  40                  45              


Trp Arg Asp Gln Lys Asn His Glu Cys Cys Met Ala Ile Leu Leu Ser 
    50                  55                  60                  


Gln Ile Val Phe Ile Glu Glu Gln Ala Ala Gly Ile Gly Lys Ser Ala 
65                  70                  75                  80  


Lys Ile Val Val His Leu His Pro Ala Pro Pro Asn Lys Glu Pro Gly 
                85                  90                  95      


Pro Phe Gln Ser Ser Lys Asn Ser Tyr Ile Lys Leu Ser Phe Lys Glu 
            100                 105                 110         


His Gly Gln Ile Glu Phe Tyr Arg Arg Leu Ser Glu Glu Met Thr Gln 
        115                 120                 125             


Arg Arg Trp Glu Asn Met Pro Val Ser Gln Ser Leu Gln Thr Asn Arg 
    130                 135                 140                 


Gly Pro Gln Pro Gly Arg Ile Arg Ala Val Gly Ile Val Gly Ile Glu 
145                 150                 155                 160 


Arg Lys Leu Glu Glu Lys Arg Lys Glu Thr Asp Lys Asn Ile Ser Glu 
                165                 170                 175     


Ala Phe Glu Asp Leu Ser Lys Leu Met Ile Lys Ala Lys Glu Met Val 
            180                 185                 190         


Glu Leu Ser Lys Ser Ile Ala Asn Lys Ile Lys Asp Lys Gln Gly Asp 
        195                 200                 205             


Ile Thr Glu Asp Glu Thr Ile Arg Phe Lys Ser Tyr Leu Leu Ser Met 
    210                 215                 220                 


Gly Ile Ala Asn Pro Val Thr Arg Glu Thr Tyr Gly Ser Gly Thr Gln 
225                 230                 235                 240 


Tyr His Met Gln Leu Ala Lys Gln Leu Ala Gly Ile Leu Gln Val Pro 
                245                 250                 255     


Leu Glu Glu Arg Gly Gly Ile Met Ser Leu Thr Glu Val Tyr Cys Leu 
            260                 265                 270         


Val Asn Arg Ala Arg Gly Met Glu Leu Leu Ser Pro Glu Asp Leu Val 
        275                 280                 285             


Asn Ala Cys Lys Met Leu Glu Ala Leu Lys Leu Pro Leu Arg Leu Arg 
    290                 295                 300                 


Val Phe Asp Ser Gly Val Met Val Ile Glu Leu Gln Ser His Lys Glu 
305                 310                 315                 320 


Glu Glu Met Val Ala Ser Ala Leu Glu Thr Val Ser Glu Lys Gly Ser 
                325                 330                 335     


Leu Thr Ser Glu Glu Phe Ala Lys Leu Val Gly Met Ser Val Leu Leu 
            340                 345                 350         


Ala Lys Glu Arg Leu Leu Leu Ala Glu Lys Met Gly His Leu Cys Arg 
        355                 360                 365             


Asp Asp Ser Val Glu Gly Leu Arg Phe Tyr Pro Asn Leu Phe Met Thr 
    370                 375                 380                 


Gln Ser 
385     


<210>  1569
<211>  122
<212>  PRT
<213>  Homo sapiens

<400>  1569

Met Glu Glu Asp Gln Glu Leu Glu Arg Lys Ala Ile Glu Glu Leu Leu 
1               5                   10                  15      


Lys Glu Ala Lys Arg Gly Lys Thr Arg Ala Glu Thr Met Gly Pro Met 
            20                  25                  30          


Gly Trp Met Lys Cys Pro Leu Ala Ser Thr Asn Lys Arg Phe Leu Ile 
        35                  40                  45              


Asn Thr Ile Lys Asn Thr Leu Pro Ser His Lys Glu Gln Asp His Glu 
    50                  55                  60                  


Gln Lys Glu Gly Asp Lys Glu Pro Ala Lys Ser Gln Ala Gln Lys Glu 
65                  70                  75                  80  


Glu Asn Pro Lys Lys His Arg Ser His Pro Tyr Lys His Ser Phe Arg 
                85                  90                  95      


Ala Arg Gly Ser Ala Ser Tyr Ser Pro Pro Arg Lys Arg Ser Ser Gln 
            100                 105                 110         


Asp Lys Tyr Glu Lys Arg Ser Asn Arg Arg 
        115                 120         


<210>  1570
<211>  406
<212>  PRT
<213>  Homo sapiens

<400>  1570

Met Ala Ala Ala Val Arg Gln Asp Leu Ala Gln Leu Met Asn Ser Ser 
1               5                   10                  15      


Gly Ser His Lys Asp Leu Ala Gly Lys Tyr Arg Gln Ile Leu Glu Lys 
            20                  25                  30          


Ala Ile Gln Leu Ser Gly Ala Glu Gln Leu Glu Ala Leu Lys Ala Phe 
        35                  40                  45              


Val Glu Ala Met Val Asn Glu Asn Val Ser Leu Val Ile Ser Arg Gln 
    50                  55                  60                  


Leu Leu Thr Asp Phe Cys Thr His Leu Pro Asn Leu Pro Asp Ser Thr 
65                  70                  75                  80  


Ala Lys Glu Ile Tyr His Phe Thr Leu Glu Lys Ile Gln Pro Arg Val 
                85                  90                  95      


Ile Ser Phe Glu Glu Gln Val Ala Ser Ile Arg Gln His Leu Ala Ser 
            100                 105                 110         


Ile Tyr Glu Lys Glu Glu Asp Trp Arg Asn Ala Ala Gln Val Leu Val 
        115                 120                 125             


Gly Ile Pro Leu Glu Thr Gly Gln Lys Gln Tyr Asn Val Asp Tyr Lys 
    130                 135                 140                 


Leu Glu Thr Tyr Leu Lys Ile Ala Arg Leu Tyr Leu Glu Asp Asp Asp 
145                 150                 155                 160 


Pro Val Gln Ala Glu Ala Tyr Ile Asn Arg Ala Ser Leu Leu Gln Asn 
                165                 170                 175     


Glu Ser Thr Asn Glu Gln Leu Gln Ile His Tyr Lys Val Cys Tyr Ala 
            180                 185                 190         


Arg Val Leu Asp Tyr Arg Arg Lys Phe Ile Glu Ala Ala Gln Arg Tyr 
        195                 200                 205             


Asn Glu Leu Ser Tyr Lys Thr Ile Val His Glu Ser Glu Arg Leu Glu 
    210                 215                 220                 


Ala Leu Lys His Ala Leu His Cys Thr Ile Leu Ala Ser Ala Gly Gln 
225                 230                 235                 240 


Gln Arg Ser Arg Met Leu Ala Thr Leu Phe Lys Asp Glu Arg Cys Gln 
                245                 250                 255     


Gln Leu Ala Ala Tyr Gly Ile Leu Glu Lys Met Tyr Leu Asp Arg Ile 
            260                 265                 270         


Ile Arg Gly Asn Gln Leu Gln Glu Phe Ala Ala Met Leu Met Pro His 
        275                 280                 285             


Gln Lys Ala Thr Thr Ala Asp Gly Ser Ser Ile Leu Asp Arg Ala Val 
    290                 295                 300                 


Ile Glu His Asn Leu Leu Ser Ala Ser Lys Leu Tyr Asn Asn Ile Thr 
305                 310                 315                 320 


Phe Glu Glu Leu Gly Ala Leu Leu Glu Ile Pro Ala Ala Lys Ala Glu 
                325                 330                 335     


Lys Ile Ala Ser Gln Met Ile Thr Glu Gly Arg Met Asn Gly Phe Ile 
            340                 345                 350         


Asp Gln Ile Asp Gly Ile Val His Phe Glu Thr Arg Glu Ala Leu Pro 
        355                 360                 365             


Thr Trp Asp Lys Gln Ile Gln Ser Leu Cys Phe Gln Val Asn Asn Leu 
    370                 375                 380                 


Leu Glu Lys Ile Ser Gln Thr Ala Pro Glu Trp Thr Ala Gln Ala Met 
385                 390                 395                 400 


Glu Ala Gln Met Ala Gln 
                405     


<210>  1571
<211>  418
<212>  PRT
<213>  Homo sapiens

<400>  1571

Met Ala Thr Ser Glu Gln Ser Ile Cys Gln Ala Arg Ala Ser Val Met 
1               5                   10                  15      


Val Tyr Asp Asp Thr Ser Lys Lys Trp Val Pro Ile Lys Pro Gly Gln 
            20                  25                  30          


Gln Gly Phe Ser Arg Ile Asn Ile Tyr His Asn Thr Ala Ser Asn Thr 
        35                  40                  45              


Phe Arg Val Val Gly Val Lys Leu Gln Asp Gln Gln Val Val Ile Asn 
    50                  55                  60                  


Tyr Ser Ile Val Lys Gly Leu Lys Tyr Asn Gln Ala Thr Pro Thr Phe 
65                  70                  75                  80  


His Gln Trp Arg Asp Ala Arg Gln Val Tyr Gly Leu Asn Phe Ala Ser 
                85                  90                  95      


Lys Glu Glu Ala Thr Thr Phe Ser Asn Ala Met Leu Phe Ala Leu Asn 
            100                 105                 110         


Ile Met Asn Ser Gln Glu Gly Gly Pro Ser Ser Gln Arg Gln Val Gln 
        115                 120                 125             


Asn Gly Pro Ser Pro Asp Glu Met Asp Ile Gln Arg Arg Gln Val Met 
    130                 135                 140                 


Glu Gln His Gln Gln Gln Arg Gln Glu Ser Leu Glu Arg Arg Thr Ser 
145                 150                 155                 160 


Ala Thr Gly Pro Ile Leu Pro Pro Gly His Pro Ser Ser Ala Ala Ser 
                165                 170                 175     


Ala Pro Val Ser Cys Ser Gly Pro Pro Pro Pro Pro Pro Pro Pro Val 
            180                 185                 190         


Pro Pro Pro Pro Thr Gly Ala Thr Pro Pro Pro Pro Pro Pro Leu Pro 
        195                 200                 205             


Ala Gly Gly Ala Gln Gly Ser Ser His Asp Glu Ser Ser Met Ser Gly 
    210                 215                 220                 


Leu Ala Ala Ala Ile Ala Gly Ala Lys Leu Arg Arg Val Gln Arg Pro 
225                 230                 235                 240 


Glu Asp Ala Ser Gly Gly Ser Ser Pro Ser Gly Thr Ser Lys Ser Asp 
                245                 250                 255     


Ala Asn Arg Ala Ser Ser Gly Gly Gly Gly Gly Gly Leu Met Glu Glu 
            260                 265                 270         


Met Asn Lys Leu Leu Ala Lys Arg Arg Lys Ala Ala Ser Gln Ser Asp 
        275                 280                 285             


Lys Pro Ala Glu Lys Lys Glu Asp Glu Ser Gln Met Glu Asp Pro Ser 
    290                 295                 300                 


Thr Ser Pro Ser Pro Gly Thr Arg Ala Ala Ser Gln Pro Pro Asn Ser 
305                 310                 315                 320 


Ser Glu Ala Gly Arg Lys Pro Trp Glu Arg Ser Asn Ser Val Glu Lys 
                325                 330                 335     


Pro Val Ser Ser Ile Leu Ser Arg Thr Pro Ser Val Ala Lys Ser Pro 
            340                 345                 350         


Glu Ala Lys Ser Pro Leu Gln Ser Gln Pro His Ser Arg Met Lys Pro 
        355                 360                 365             


Ala Gly Ser Val Asn Asp Met Ala Leu Asp Ala Phe Asp Leu Asp Arg 
    370                 375                 380                 


Met Lys Gln Glu Ile Leu Glu Glu Val Val Arg Glu Leu His Lys Val 
385                 390                 395                 400 


Lys Glu Glu Ile Ile Asp Ala Ile Arg Gln Glu Leu Ser Gly Ile Ser 
                405                 410                 415     


Thr Thr 
        


<210>  1572
<211>  723
<212>  PRT
<213>  Homo sapiens

<400>  1572

Met Ser Thr Ala Thr Gly Pro Glu Ala Ala Pro Lys Pro Ser Ala Lys 
1               5                   10                  15      


Ser Ile Tyr Glu Gln Arg Lys Arg Tyr Ser Thr Val Val Met Ala Asp 
            20                  25                  30          


Val Ser Gln Tyr Pro Val Asn His Leu Val Thr Phe Cys Leu Gly Glu 
        35                  40                  45              


Asp Asp Gly Val His Thr Val Glu Asp Ala Ser Arg Lys Leu Ala Val 
    50                  55                  60                  


Met Asp Ser Gln Gly Arg Val Trp Ala Gln Glu Met Leu Leu Arg Val 
65                  70                  75                  80  


Ser Pro Asp His Val Thr Leu Leu Asp Pro Ala Ser Lys Glu Glu Leu 
                85                  90                  95      


Glu Ser Tyr Pro Leu Gly Ala Ile Val Arg Cys Asp Ala Val Met Pro 
            100                 105                 110         


Pro Gly Arg Ser Arg Ser Leu Leu Leu Leu Val Cys Gln Glu Pro Glu 
        115                 120                 125             


Arg Ala Gln Pro Asp Val His Phe Phe Gln Gly Leu Arg Leu Gly Ala 
    130                 135                 140                 


Glu Leu Ile Arg Glu Asp Ile Gln Gly Ala Leu His Asn Tyr Arg Ser 
145                 150                 155                 160 


Gly Arg Gly Glu Arg Arg Ala Ala Ala Leu Arg Ala Thr Gln Glu Glu 
                165                 170                 175     


Leu Gln Arg Asp Arg Ser Pro Ala Ala Glu Thr Pro Pro Leu Gln Arg 
            180                 185                 190         


Arg Pro Ser Val Arg Ala Val Ile Ser Thr Val Glu Arg Gly Ala Gly 
        195                 200                 205             


Arg Gly Arg Pro Gln Ala Lys Pro Ile Pro Glu Ala Glu Glu Ala Gln 
    210                 215                 220                 


Arg Pro Glu Pro Val Gly Thr Ser Ser Asn Ala Asp Ser Ala Ser Pro 
225                 230                 235                 240 


Asp Leu Gly Pro Arg Gly Pro Asp Leu Ala Val Leu Gln Ala Glu Arg 
                245                 250                 255     


Glu Val Asp Ile Leu Asn His Val Phe Asp Asp Val Glu Ser Phe Val 
            260                 265                 270         


Ser Arg Leu Gln Lys Ser Ala Glu Ala Ala Arg Val Leu Glu His Arg 
        275                 280                 285             


Glu Arg Gly Arg Arg Ser Arg Arg Arg Ala Ala Gly Glu Gly Leu Leu 
    290                 295                 300                 


Thr Leu Arg Ala Lys Pro Pro Ser Glu Ala Glu Tyr Thr Asp Val Leu 
305                 310                 315                 320 


Gln Lys Ile Lys Tyr Ala Phe Ser Leu Leu Ala Arg Leu Arg Gly Asn 
                325                 330                 335     


Ile Ala Asp Pro Ser Ser Pro Glu Leu Leu His Phe Leu Phe Gly Pro 
            340                 345                 350         


Leu Gln Met Ile Val Asn Thr Ser Gly Gly Pro Glu Phe Ala Ser Ser 
        355                 360                 365             


Val Arg Arg Pro His Leu Thr Ser Asp Ala Val Ala Leu Leu Arg Asp 
    370                 375                 380                 


Asn Val Thr Pro Arg Glu Asn Glu Leu Trp Thr Ser Leu Gly Asp Ser 
385                 390                 395                 400 


Trp Thr Arg Pro Gly Leu Glu Leu Ser Pro Glu Glu Gly Pro Pro Tyr 
                405                 410                 415     


Arg Pro Glu Phe Phe Ser Gly Trp Glu Pro Pro Val Thr Asp Pro Gln 
            420                 425                 430         


Ser Arg Ala Trp Glu Asp Pro Val Glu Lys Gln Leu Gln His Glu Arg 
        435                 440                 445             


Arg Arg Arg Gln Gln Ser Ala Pro Gln Val Ala Val Asn Gly His Arg 
    450                 455                 460                 


Asp Leu Glu Pro Glu Ser Glu Pro Gln Leu Glu Ser Glu Thr Ala Gly 
465                 470                 475                 480 


Lys Trp Val Leu Cys Asn Tyr Asp Phe Gln Ala Arg Asn Ser Ser Glu 
                485                 490                 495     


Leu Ser Val Lys Gln Arg Asp Val Leu Glu Val Leu Asp Asp Ser Arg 
            500                 505                 510         


Lys Trp Trp Lys Val Arg Asp Pro Ala Gly Gln Glu Gly Tyr Val Pro 
        515                 520                 525             


Tyr Asn Ile Leu Thr Pro Tyr Pro Gly Pro Arg Leu His His Ser Gln 
    530                 535                 540                 


Ser Pro Ala Arg Ser Leu Asn Ser Thr Pro Pro Pro Pro Pro Ala Pro 
545                 550                 555                 560 


Ala Pro Ala Pro Pro Pro Ala Leu Ala Arg Pro Arg Trp Asp Arg Pro 
                565                 570                 575     


Arg Trp Asp Ser Cys Asp Ser Leu Asn Gly Leu Asp Pro Ser Glu Lys 
            580                 585                 590         


Glu Lys Phe Ser Gln Met Leu Ile Val Asn Glu Glu Leu Gln Ala Arg 
        595                 600                 605             


Leu Ala Gln Gly Arg Ser Gly Pro Ser Arg Ala Val Pro Gly Pro Arg 
    610                 615                 620                 


Ala Pro Glu Pro Gln Leu Ser Pro Gly Ser Asp Ala Ser Glu Val Arg 
625                 630                 635                 640 


Ala Trp Leu Gln Ala Lys Gly Phe Ser Ser Gly Thr Val Asp Ala Leu 
                645                 650                 655     


Gly Val Leu Thr Gly Ala Gln Leu Phe Ser Leu Gln Lys Glu Glu Leu 
            660                 665                 670         


Arg Ala Val Ser Pro Glu Glu Gly Ala Arg Val Tyr Ser Gln Val Thr 
        675                 680                 685             


Val Gln Arg Ser Leu Leu Glu Asp Lys Glu Lys Val Ser Glu Leu Glu 
    690                 695                 700                 


Ala Val Met Glu Lys Gln Lys Lys Lys Val Glu Gly Glu Val Glu Met 
705                 710                 715                 720 


Glu Val Ile 
            


<210>  1573
<211>  559
<212>  PRT
<213>  Homo sapiens

<400>  1573

Met Ala Glu Thr Val Trp Ser Thr Asp Thr Gly Glu Ala Val Tyr Arg 
1               5                   10                  15      


Ser Arg Asp Pro Val Arg Asn Leu Arg Leu Arg Val His Leu Gln Arg 
            20                  25                  30          


Ile Thr Ser Ser Asn Phe Leu His Tyr Gln Pro Ala Ala Glu Leu Gly 
        35                  40                  45              


Lys Asp Leu Ile Asp Leu Ala Thr Phe Arg Pro Gln Pro Thr Ala Ser 
    50                  55                  60                  


Gly His Arg Pro Glu Glu Asp Glu Glu Glu Glu Ile Val Ile Gly Trp 
65                  70                  75                  80  


Gln Glu Lys Leu Phe Ser Gln Phe Glu Val Asp Leu Tyr Gln Asn Glu 
                85                  90                  95      


Thr Ala Cys Gln Ser Pro Leu Asp Tyr Gln Tyr Arg Gln Glu Ile Leu 
            100                 105                 110         


Lys Leu Glu Asn Ser Gly Gly Lys Lys Asn Arg Arg Ile Phe Thr Tyr 
        115                 120                 125             


Thr Asp Ser Asp Arg Tyr Thr Asn Leu Glu Glu His Cys Gln Arg Met 
    130                 135                 140                 


Thr Thr Ala Ala Ser Glu Val Pro Ser Phe Leu Val Glu Arg Met Ala 
145                 150                 155                 160 


Asn Val Arg Arg Arg Arg Gln Asp Arg Arg Gly Met Glu Gly Gly Ile 
                165                 170                 175     


Leu Lys Ser Arg Ile Val Thr Trp Glu Pro Ser Glu Glu Phe Val Arg 
            180                 185                 190         


Asn Asn His Val Ile Asn Thr Pro Leu Gln Thr Met His Ile Met Ala 
        195                 200                 205             


Asp Leu Gly Pro Tyr Lys Lys Leu Gly Tyr Lys Lys Tyr Glu His Val 
    210                 215                 220                 


Leu Cys Thr Leu Lys Val Asp Ser Asn Gly Val Ile Thr Val Lys Pro 
225                 230                 235                 240 


Asp Phe Thr Gly Leu Lys Gly Pro Tyr Arg Ile Glu Thr Glu Gly Glu 
                245                 250                 255     


Lys Gln Glu Leu Trp Lys Tyr Thr Ile Asp Asn Val Ser Pro His Ala 
            260                 265                 270         


Gln Pro Glu Glu Glu Glu Arg Glu Arg Arg Val Phe Lys Asp Leu Tyr 
        275                 280                 285             


Gly Arg His Lys Glu Tyr Leu Ser Ser Leu Val Gly Thr Asp Phe Glu 
    290                 295                 300                 


Met Thr Val Pro Gly Ala Leu Arg Leu Phe Val Asn Gly Glu Val Val 
305                 310                 315                 320 


Ser Ala Gln Gly Tyr Glu Tyr Asp Asn Leu Tyr Val His Phe Phe Val 
                325                 330                 335     


Glu Leu Pro Thr Ala His Trp Ser Ser Pro Ala Phe Gln Gln Leu Ser 
            340                 345                 350         


Gly Val Thr Gln Thr Cys Thr Thr Lys Ser Leu Ala Met Asp Lys Val 
        355                 360                 365             


Ala His Phe Ser Tyr Pro Phe Thr Phe Glu Ala Phe Phe Leu His Glu 
    370                 375                 380                 


Asp Glu Ser Ser Asp Ala Leu Pro Glu Trp Pro Val Leu Tyr Cys Glu 
385                 390                 395                 400 


Val Leu Ser Leu Asp Phe Trp Gln Arg Tyr Arg Val Glu Gly Tyr Gly 
                405                 410                 415     


Ala Val Val Leu Pro Ala Thr Pro Gly Ser His Thr Leu Thr Val Ser 
            420                 425                 430         


Thr Trp Arg Pro Val Glu Leu Gly Thr Val Ala Glu Leu Arg Arg Phe 
        435                 440                 445             


Phe Ile Gly Gly Ser Leu Glu Leu Glu Asp Leu Ser Tyr Val Arg Ile 
    450                 455                 460                 


Pro Gly Ser Phe Lys Gly Glu Arg Leu Ser Arg Phe Gly Leu Arg Thr 
465                 470                 475                 480 


Glu Thr Thr Gly Thr Val Thr Phe Arg Leu His Cys Leu Gln Gln Ser 
                485                 490                 495     


Arg Ala Phe Met Glu Ser Ser Ser Leu Gln Lys Arg Met Arg Ser Val 
            500                 505                 510         


Leu Asp Arg Leu Glu Gly Phe Ser Gln Gln Ser Ser Ile His Asn Val 
        515                 520                 525             


Leu Glu Ala Phe Arg Arg Ala Arg Arg Arg Met Gln Glu Ala Arg Glu 
    530                 535                 540                 


Ser Leu Pro Gln Asp Leu Val Ser Pro Ser Gly Thr Leu Val Ser 
545                 550                 555                 


<210>  1574
<211>  318
<212>  PRT
<213>  Homo sapiens

<400>  1574

Met Ala Ala Ala Ala Val Ser Gly Ala Leu Gly Arg Ala Gly Trp Arg 
1               5                   10                  15      


Leu Leu Gln Leu Arg Cys Leu Pro Val Ala Arg Cys Arg Gln Ala Leu 
            20                  25                  30          


Val Pro Arg Ala Phe His Ala Ser Ala Val Gly Leu Arg Ser Ser Asp 
        35                  40                  45              


Glu Gln Lys Gln Gln Pro Pro Asn Ser Phe Ser Gln Gln His Ser Glu 
    50                  55                  60                  


Thr Gln Gly Ala Glu Lys Pro Asp Pro Glu Ser Ser His Ser Pro Pro 
65                  70                  75                  80  


Arg Tyr Thr Asp Gln Gly Gly Glu Glu Glu Glu Asp Tyr Glu Ser Glu 
                85                  90                  95      


Glu Gln Leu Gln His Arg Ile Leu Thr Ala Ala Leu Glu Phe Val Pro 
            100                 105                 110         


Ala His Gly Trp Thr Ala Glu Ala Ile Ala Glu Gly Ala Gln Ser Leu 
        115                 120                 125             


Gly Leu Ser Ser Ala Ala Ala Ser Met Phe Gly Lys Asp Gly Ser Glu 
    130                 135                 140                 


Leu Ile Leu His Phe Val Thr Gln Cys Asn Thr Arg Leu Thr Arg Val 
145                 150                 155                 160 


Leu Glu Glu Glu Gln Lys Leu Val Gln Leu Gly Gln Ala Glu Lys Arg 
                165                 170                 175     


Lys Thr Asp Gln Phe Leu Arg Asp Ala Val Glu Thr Arg Leu Arg Met 
            180                 185                 190         


Leu Ile Pro Tyr Ile Glu His Trp Pro Arg Ala Leu Ser Ile Leu Met 
        195                 200                 205             


Leu Pro His Asn Ile Pro Ser Ser Leu Ser Leu Leu Thr Ser Met Val 
    210                 215                 220                 


Asp Asp Met Trp His Tyr Ala Gly Asp Gln Ser Thr Asp Phe Asn Trp 
225                 230                 235                 240 


Tyr Thr Arg Arg Ala Met Leu Ala Ala Ile Tyr Asn Thr Thr Glu Leu 
                245                 250                 255     


Val Met Met Gln Asp Ser Ser Pro Asp Phe Glu Asp Thr Trp Arg Phe 
            260                 265                 270         


Leu Glu Asn Arg Val Asn Asp Ala Met Asn Met Gly His Thr Ala Lys 
        275                 280                 285             


Gln Val Lys Ser Thr Gly Glu Ala Leu Val Gln Gly Leu Met Gly Ala 
    290                 295                 300                 


Ala Val Thr Leu Lys Asn Leu Thr Gly Leu Asn Gln Arg Arg 
305                 310                 315             


<210>  1575
<211>  296
<212>  PRT
<213>  Homo sapiens

<400>  1575

Met Ala Arg Cys Glu Arg Leu Arg Gly Ala Ala Leu Arg Asp Val Leu 
1               5                   10                  15      


Gly Arg Ala Gln Gly Val Leu Phe Asp Cys Asp Gly Val Leu Trp Asn 
            20                  25                  30          


Gly Glu Arg Ala Val Pro Gly Ala Pro Glu Leu Leu Glu Arg Leu Ala 
        35                  40                  45              


Arg Ala Gly Lys Ala Ala Leu Phe Val Ser Asn Asn Ser Arg Arg Ala 
    50                  55                  60                  


Arg Pro Glu Leu Ala Leu Arg Phe Ala Arg Leu Gly Phe Gly Gly Leu 
65                  70                  75                  80  


Arg Ala Glu Gln Leu Phe Ser Ser Ala Leu Cys Ala Ala Arg Leu Leu 
                85                  90                  95      


Arg Gln Arg Leu Pro Gly Pro Pro Asp Ala Pro Gly Ala Val Phe Val 
            100                 105                 110         


Leu Gly Gly Glu Gly Leu Arg Ala Glu Leu Arg Ala Ala Gly Leu Arg 
        115                 120                 125             


Leu Ala Gly Asp Pro Ser Ala Gly Asp Gly Ala Ala Pro Arg Val Arg 
    130                 135                 140                 


Ala Val Leu Val Gly Tyr Asp Glu His Phe Ser Phe Ala Lys Leu Arg 
145                 150                 155                 160 


Glu Ala Cys Ala His Leu Arg Asp Pro Glu Cys Leu Leu Val Ala Thr 
                165                 170                 175     


Asp Arg Asp Pro Trp His Pro Leu Ser Asp Gly Ser Arg Thr Pro Gly 
            180                 185                 190         


Thr Gly Ser Leu Ala Ala Ala Val Glu Thr Ala Ser Gly Arg Gln Ala 
        195                 200                 205             


Leu Val Val Gly Lys Pro Ser Pro Tyr Met Phe Glu Cys Ile Thr Glu 
    210                 215                 220                 


Asn Phe Ser Ile Asp Pro Ala Arg Thr Leu Met Val Gly Asp Arg Leu 
225                 230                 235                 240 


Glu Thr Asp Ile Leu Phe Gly His Arg Cys Gly Met Thr Thr Val Leu 
                245                 250                 255     


Thr Leu Thr Gly Val Ser Arg Leu Glu Glu Ala Gln Ala Tyr Leu Ala 
            260                 265                 270         


Ala Gly Gln His Asp Leu Val Pro His Tyr Tyr Val Glu Ser Ile Ala 
        275                 280                 285             


Asp Leu Thr Glu Gly Leu Glu Asp 
    290                 295     


<210>  1576
<211>  2177
<212>  PRT
<213>  Homo sapiens

<400>  1576

Met Glu Glu Ile Leu Arg Lys Leu Gln Lys Glu Ala Ser Gly Ser Lys 
1               5                   10                  15      


Tyr Lys Ala Ile Lys Glu Ser Cys Thr Trp Ala Leu Glu Thr Leu Gly 
            20                  25                  30          


Gly Leu Asp Thr Ile Val Lys Ile Pro Pro His Val Leu Arg Glu Lys 
        35                  40                  45              


Cys Leu Leu Pro Leu Gln Leu Ala Leu Glu Ser Lys Asn Val Lys Leu 
    50                  55                  60                  


Ala Gln His Ala Leu Ala Gly Met Gln Lys Leu Leu Ser Glu Glu Arg 
65                  70                  75                  80  


Phe Val Ser Met Glu Thr Asp Ser Asp Glu Lys Gln Leu Leu Asn Gln 
                85                  90                  95      


Ile Leu Asn Ala Val Lys Val Thr Pro Ser Leu Asn Glu Asp Leu Gln 
            100                 105                 110         


Val Glu Val Met Lys Val Leu Leu Cys Ile Thr Tyr Thr Pro Thr Phe 
        115                 120                 125             


Asp Leu Asn Gly Ser Ala Val Leu Lys Ile Ala Glu Val Cys Ile Glu 
    130                 135                 140                 


Thr Tyr Ile Ser Ser Cys His Gln Arg Ser Ile Asn Thr Ala Val Arg 
145                 150                 155                 160 


Ala Thr Leu Ser Gln Met Leu Ser Asp Leu Thr Leu Gln Leu Arg Gln 
                165                 170                 175     


Arg Gln Glu Asn Thr Ile Ile Glu Asn Pro Asp Val Pro Gln Asp Phe 
            180                 185                 190         


Gly Asn Gln Gly Ser Thr Val Glu Ser Leu Cys Asp Asp Val Val Ser 
        195                 200                 205             


Val Leu Thr Val Leu Cys Glu Lys Leu Gln Ala Ala Ile Asn Asp Ser 
    210                 215                 220                 


Gln Gln Leu Gln Leu Leu Tyr Leu Glu Cys Ile Leu Ser Val Leu Ser 
225                 230                 235                 240 


Ser Ser Ser Ser Ser Met His Leu His Arg Arg Phe Thr Asp Leu Ile 
                245                 250                 255     


Trp Lys Asn Leu Cys Pro Ala Leu Ile Val Ile Leu Gly Asn Pro Ile 
            260                 265                 270         


His Asp Lys Thr Ile Thr Ser Ala His Thr Ser Ser Thr Ser Thr Ser 
        275                 280                 285             


Leu Glu Ser Asp Ser Ala Ser Pro Gly Val Ser Asp His Gly Arg Gly 
    290                 295                 300                 


Ser Gly Cys Ser Cys Thr Ala Pro Ala Leu Ser Gly Pro Val Ala Arg 
305                 310                 315                 320 


Thr Ile Tyr Tyr Ile Ala Ala Glu Leu Val Arg Leu Val Gly Ser Val 
                325                 330                 335     


Asp Ser Met Lys Pro Val Leu Gln Ser Leu Tyr His Arg Val Leu Leu 
            340                 345                 350         


Tyr Pro Pro Pro Gln His Arg Val Glu Ala Ile Lys Ile Met Lys Glu 
        355                 360                 365             


Ile Leu Gly Ser Pro Gln Arg Leu Cys Asp Leu Ala Gly Pro Ser Ser 
    370                 375                 380                 


Thr Glu Ser Glu Ser Arg Lys Arg Ser Ile Ser Lys Arg Lys Ser His 
385                 390                 395                 400 


Leu Asp Leu Leu Lys Leu Ile Met Asp Gly Met Thr Glu Ala Cys Ile 
                405                 410                 415     


Lys Gly Gly Ile Glu Ala Cys Tyr Ala Ala Val Ser Cys Val Cys Thr 
            420                 425                 430         


Leu Leu Gly Ala Leu Asp Glu Leu Ser Gln Gly Lys Gly Leu Ser Glu 
        435                 440                 445             


Gly Gln Val Gln Leu Leu Leu Leu Arg Leu Glu Glu Leu Lys Asp Gly 
    450                 455                 460                 


Ala Glu Trp Ser Arg Asp Ser Met Glu Ile Asn Glu Ala Asp Phe Arg 
465                 470                 475                 480 


Trp Gln Arg Arg Val Leu Ser Ser Glu His Thr Pro Trp Glu Ser Gly 
                485                 490                 495     


Asn Glu Arg Ser Leu Asp Ile Ser Ile Ser Val Thr Thr Asp Thr Gly 
            500                 505                 510         


Gln Thr Thr Leu Glu Gly Glu Leu Gly Gln Thr Thr Pro Glu Asp His 
        515                 520                 525             


Ser Gly Asn His Lys Asn Ser Leu Lys Ser Pro Ala Ile Pro Glu Gly 
    530                 535                 540                 


Lys Glu Thr Leu Ser Lys Val Leu Glu Thr Glu Ala Val Asp Gln Pro 
545                 550                 555                 560 


Asp Val Val Gln Arg Ser His Thr Val Pro Tyr Pro Asp Ile Thr Asn 
                565                 570                 575     


Phe Leu Ser Val Asp Cys Arg Thr Arg Ser Tyr Gly Ser Arg Tyr Ser 
            580                 585                 590         


Glu Ser Asn Phe Ser Val Asp Asp Gln Asp Leu Ser Arg Thr Glu Phe 
        595                 600                 605             


Asp Ser Cys Asp Gln Tyr Ser Met Ala Ala Glu Lys Asp Ser Gly Arg 
    610                 615                 620                 


Ser Asp Val Ser Asp Ile Gly Ser Asp Asn Cys Ser Leu Ala Asp Glu 
625                 630                 635                 640 


Glu Gln Thr Pro Arg Asp Cys Leu Gly His Arg Ser Leu Arg Thr Ala 
                645                 650                 655     


Ala Leu Ser Leu Lys Leu Leu Lys Asn Gln Glu Ala Asp Gln His Ser 
            660                 665                 670         


Ala Arg Leu Phe Ile Gln Ser Leu Glu Gly Leu Leu Pro Arg Leu Leu 
        675                 680                 685             


Ser Leu Ser Asn Val Glu Glu Val Asp Thr Ala Leu Gln Asn Phe Ala 
    690                 695                 700                 


Ser Thr Phe Cys Ser Gly Met Met His Ser Pro Gly Phe Asp Gly Asn 
705                 710                 715                 720 


Ser Ser Leu Ser Phe Gln Met Leu Met Asn Ala Asp Ser Leu Tyr Thr 
                725                 730                 735     


Ala Ala His Cys Ala Leu Leu Leu Asn Leu Lys Leu Ser His Gly Asp 
            740                 745                 750         


Tyr Tyr Arg Lys Arg Pro Thr Leu Ala Pro Gly Val Met Lys Asp Phe 
        755                 760                 765             


Met Lys Gln Val Gln Thr Ser Gly Val Leu Met Val Phe Ser Gln Ala 
    770                 775                 780                 


Trp Ile Glu Glu Leu Tyr His Gln Val Leu Asp Arg Asn Met Leu Gly 
785                 790                 795                 800 


Glu Ala Gly Tyr Trp Gly Ser Pro Glu Asp Asn Ser Leu Pro Leu Ile 
                805                 810                 815     


Thr Met Leu Thr Asp Ile Asp Gly Leu Glu Ser Ser Ala Ile Gly Gly 
            820                 825                 830         


Gln Leu Met Ala Ser Ala Ala Thr Glu Ser Pro Phe Ala Gln Ser Arg 
        835                 840                 845             


Arg Ile Asp Asp Ser Thr Val Ala Gly Val Ala Phe Ala Arg Tyr Ile 
    850                 855                 860                 


Leu Val Gly Cys Trp Lys Asn Leu Ile Asp Thr Leu Ser Thr Pro Leu 
865                 870                 875                 880 


Thr Gly Arg Met Ala Gly Ser Ser Lys Gly Leu Ala Phe Ile Leu Gly 
                885                 890                 895     


Ala Glu Gly Ile Lys Glu Gln Asn Gln Lys Glu Arg Asp Ala Ile Cys 
            900                 905                 910         


Met Ser Leu Asp Gly Leu Arg Lys Ala Ala Arg Leu Ser Cys Ala Leu 
        915                 920                 925             


Gly Val Ala Ala Asn Cys Ala Ser Ala Leu Ala Gln Met Ala Ala Ala 
    930                 935                 940                 


Ser Cys Val Gln Glu Glu Lys Glu Glu Arg Glu Ala Gln Glu Pro Ser 
945                 950                 955                 960 


Asp Ala Ile Thr Gln Val Lys Leu Lys Val Glu Gln Lys Leu Glu Gln 
                965                 970                 975     


Ile Gly Lys Val Gln Gly Val Trp Leu His Thr Ala His Val Leu Cys 
            980                 985                 990         


Met Glu Ala Ile Leu Ser Val Gly  Leu Glu Met Gly Ser  His Asn Pro 
        995                 1000                 1005             


Asp Cys  Trp Pro His Val Phe  Arg Val Cys Glu Tyr  Val Gly Thr 
    1010                 1015                 1020             


Leu Glu  His Asn His Phe Ser  Asp Gly Ala Ser Gln  Pro Pro Leu 
    1025                 1030                 1035             


Thr Ile  Ser Gln Pro Gln Lys  Ala Thr Gly Ser Ala  Gly Leu Leu 
    1040                 1045                 1050             


Gly Asp  Pro Glu Cys Glu Gly  Ser Pro Pro Glu His  Ser Pro Glu 
    1055                 1060                 1065             


Gln Gly  Arg Ser Leu Ser Thr  Ala Pro Val Val Gln  Pro Leu Ser 
    1070                 1075                 1080             


Ile Gln  Asp Leu Val Arg Glu  Gly Ser Arg Gly Arg  Ala Ser Asp 
    1085                 1090                 1095             


Phe Arg  Gly Gly Ser Leu Met  Ser Gly Ser Ser Ala  Ala Lys Val 
    1100                 1105                 1110             


Val Leu  Thr Leu Ser Thr Gln  Ala Asp Arg Leu Phe  Glu Asp Ala 
    1115                 1120                 1125             


Thr Asp  Lys Leu Asn Leu Met  Ala Leu Gly Gly Phe  Leu Tyr Gln 
    1130                 1135                 1140             


Leu Lys  Lys Ala Ser Gln Ser  Gln Leu Phe His Ser  Val Thr Asp 
    1145                 1150                 1155             


Thr Val  Asp Tyr Ser Leu Ala  Met Pro Gly Glu Val  Lys Ser Thr 
    1160                 1165                 1170             


Gln Asp  Arg Lys Ser Ala Leu  His Leu Phe Arg Leu  Gly Asn Ala 
    1175                 1180                 1185             


Met Leu  Arg Ile Val Arg Ser  Lys Ala Arg Pro Leu  Leu His Val 
    1190                 1195                 1200             


Met Arg  Cys Trp Ser Leu Val  Ala Pro His Leu Val  Glu Ala Ala 
    1205                 1210                 1215             


Cys His  Lys Glu Arg His Val  Ser Gln Lys Ala Val  Ser Phe Ile 
    1220                 1225                 1230             


His Asp  Ile Leu Thr Glu Val  Leu Thr Asp Trp Asn  Glu Pro Pro 
    1235                 1240                 1245             


His Phe  His Phe Asn Glu Ala  Leu Phe Arg Pro Phe  Glu Arg Ile 
    1250                 1255                 1260             


Met Gln  Leu Glu Leu Cys Asp  Glu Asp Val Gln Asp  Gln Val Val 
    1265                 1270                 1275             


Thr Ser  Ile Gly Glu Leu Val  Glu Val Cys Ser Thr  Gln Ile Gln 
    1280                 1285                 1290             


Ser Gly  Trp Arg Pro Leu Phe  Ser Ala Leu Glu Thr  Val His Gly 
    1295                 1300                 1305             


Gly Asn  Lys Ser Glu Met Lys  Glu Tyr Leu Val Gly  Asp Tyr Ser 
    1310                 1315                 1320             


Met Gly  Lys Gly Gln Ala Pro  Val Phe Asp Val Phe  Glu Ala Phe 
    1325                 1330                 1335             


Leu Asn  Thr Asp Asn Ile Gln  Val Phe Ala Asn Ala  Ala Thr Ser 
    1340                 1345                 1350             


Tyr Ile  Met Cys Leu Met Lys  Phe Val Lys Gly Leu  Gly Glu Val 
    1355                 1360                 1365             


Asp Cys  Lys Glu Ile Gly Asp  Cys Ala Pro Ala Pro  Gly Ala Pro 
    1370                 1375                 1380             


Ser Thr  Asp Leu Cys Leu Pro  Ala Leu Asp Tyr Leu  Arg Arg Cys 
    1385                 1390                 1395             


Ser Gln  Leu Leu Ala Lys Ile  Tyr Lys Met Pro Leu  Lys Pro Ile 
    1400                 1405                 1410             


Phe Leu  Ser Gly Arg Leu Ala  Gly Leu Pro Arg Arg  Leu Gln Glu 
    1415                 1420                 1425             


Gln Ser  Ala Ser Ser Glu Asp  Gly Ile Glu Ser Val  Leu Ser Asp 
    1430                 1435                 1440             


Phe Asp  Asp Asp Thr Gly Leu  Ile Glu Val Trp Ile  Ile Leu Leu 
    1445                 1450                 1455             


Glu Gln  Leu Thr Ala Ala Val  Ser Asn Cys Pro Arg  Gln His Gln 
    1460                 1465                 1470             


Pro Pro  Thr Leu Asp Leu Leu  Phe Glu Leu Leu Arg  Asp Val Thr 
    1475                 1480                 1485             


Lys Thr  Pro Gly Pro Gly Phe  Gly Ile Tyr Ala Val  Val His Leu 
    1490                 1495                 1500             


Leu Leu  Pro Val Met Ser Val  Trp Leu Arg Arg Ser  His Lys Asp 
    1505                 1510                 1515             


His Ser  Tyr Trp Asp Met Ala  Ser Ala Asn Phe Lys  His Ala Ile 
    1520                 1525                 1530             


Gly Leu  Ser Cys Glu Leu Val  Val Glu His Ile Gln  Ser Phe Leu 
    1535                 1540                 1545             


His Ser  Asp Ile Arg Tyr Glu  Ser Met Ile Asn Thr  Met Leu Lys 
    1550                 1555                 1560             


Asp Leu  Phe Glu Leu Leu Val  Ala Cys Val Ala Lys  Pro Thr Glu 
    1565                 1570                 1575             


Thr Ile  Ser Arg Val Gly Cys  Ser Cys Ile Arg Tyr  Val Leu Val 
    1580                 1585                 1590             


Thr Ala  Gly Pro Val Phe Thr  Glu Glu Met Trp Arg  Leu Ala Cys 
    1595                 1600                 1605             


Cys Ala  Leu Gln Asp Ala Phe  Ser Ala Thr Leu Lys  Pro Val Lys 
    1610                 1615                 1620             


Asp Leu  Leu Gly Cys Phe His  Ser Gly Thr Glu Ser  Phe Ser Gly 
    1625                 1630                 1635             


Glu Gly  Cys Gln Val Arg Val  Ala Ala Pro Ser Ser  Ser Pro Ser 
    1640                 1645                 1650             


Ala Glu  Ala Glu Tyr Trp Arg  Ile Arg Ala Met Ala  Gln Gln Val 
    1655                 1660                 1665             


Phe Met  Leu Asp Thr Gln Cys  Ser Pro Lys Thr Pro  Asn Asn Phe 
    1670                 1675                 1680             


Asp His  Ala Gln Ser Cys Gln  Leu Ile Ile Glu Leu  Pro Pro Asp 
    1685                 1690                 1695             


Glu Lys  Pro Asn Gly His Thr  Lys Lys Ser Val Ser  Phe Arg Glu 
    1700                 1705                 1710             


Ile Val  Val Ser Leu Leu Ser  His Gln Val Leu Leu  Gln Asn Leu 
    1715                 1720                 1725             


Tyr Asp  Ile Leu Leu Glu Glu  Phe Val Lys Gly Pro  Ser Pro Gly 
    1730                 1735                 1740             


Glu Glu  Lys Thr Ile Gln Val  Pro Glu Ala Lys Leu  Ala Gly Phe 
    1745                 1750                 1755             


Leu Arg  Tyr Ile Ser Met Gln  Asn Leu Ala Val Ile  Phe Asp Leu 
    1760                 1765                 1770             


Leu Leu  Asp Ser Tyr Arg Thr  Ala Arg Glu Phe Asp  Thr Ser Pro 
    1775                 1780                 1785             


Gly Leu  Lys Cys Leu Leu Lys  Lys Val Ser Gly Ile  Gly Gly Ala 
    1790                 1795                 1800             


Ala Asn  Leu Tyr Arg Gln Ser  Ala Met Ser Phe Asn  Ile Tyr Phe 
    1805                 1810                 1815             


His Ala  Leu Val Cys Ala Val  Leu Thr Asn Gln Glu  Thr Ile Thr 
    1820                 1825                 1830             


Ala Glu  Gln Val Lys Lys Val  Leu Phe Glu Asp Asp  Glu Arg Ser 
    1835                 1840                 1845             


Thr Asp  Ser Ser Gln Gln Cys  Ser Ser Glu Asp Glu  Asp Ile Phe 
    1850                 1855                 1860             


Glu Glu  Thr Ala Gln Val Ser  Pro Pro Arg Gly Lys  Glu Lys Arg 
    1865                 1870                 1875             


Gln Trp  Arg Ala Arg Met Pro  Leu Leu Ser Val Gln  Pro Val Ser 
    1880                 1885                 1890             


Asn Ala  Asp Trp Val Trp Leu  Val Lys Arg Leu His  Lys Leu Cys 
    1895                 1900                 1905             


Met Glu  Leu Cys Asn Asn Tyr  Ile Gln Met His Leu  Asp Leu Glu 
    1910                 1915                 1920             


Asn Cys  Met Glu Glu Pro Pro  Ile Phe Lys Gly Asp  Pro Phe Phe 
    1925                 1930                 1935             


Ile Leu  Pro Ser Phe Gln Ser  Glu Ser Ser Thr Pro  Ser Thr Gly 
    1940                 1945                 1950             


Gly Phe  Ser Gly Lys Glu Thr  Pro Ser Glu Asp Asp  Arg Ser Gln 
    1955                 1960                 1965             


Ser Arg  Glu His Met Gly Glu  Ser Leu Ser Leu Lys  Ala Gly Gly 
    1970                 1975                 1980             


Gly Asp  Leu Leu Leu Pro Pro  Ser Pro Lys Val Glu  Lys Lys Asp 
    1985                 1990                 1995             


Pro Ser  Arg Lys Lys Glu Trp  Trp Glu Asn Ala Gly  Asn Lys Ile 
    2000                 2005                 2010             


Tyr Thr  Met Ala Ala Asp Lys  Thr Ile Ser Lys Leu  Met Thr Glu 
    2015                 2020                 2025             


Tyr Lys  Lys Arg Lys Gln Gln  His Asn Leu Ser Ala  Phe Pro Lys 
    2030                 2035                 2040             


Glu Val  Lys Val Glu Lys Lys  Gly Glu Pro Leu Gly  Pro Arg Gly 
    2045                 2050                 2055             


Gln Asp  Ser Pro Leu Leu Gln  Arg Pro Gln His Leu  Met Asp Gln 
    2060                 2065                 2070             


Gly Gln  Met Arg His Ser Phe  Ser Ala Gly Pro Glu  Leu Leu Arg 
    2075                 2080                 2085             


Gln Asp  Lys Arg Pro Arg Ser  Gly Ser Thr Gly Ser  Ser Leu Ser 
    2090                 2095                 2100             


Val Ser  Val Arg Asp Ala Glu  Ala Gln Ile Gln Ala  Trp Thr Asn 
    2105                 2110                 2115             


Met Val  Leu Thr Val Leu Asn  Gln Ile Gln Ile Leu  Pro Asp Gln 
    2120                 2125                 2130             


Thr Phe  Thr Ala Leu Gln Pro  Ala Val Phe Pro Cys  Ile Ser Gln 
    2135                 2140                 2145             


Leu Thr  Cys His Val Thr Asp  Ile Arg Val Arg Gln  Ala Val Arg 
    2150                 2155                 2160             


Glu Trp  Leu Gly Arg Val Gly  Arg Val Tyr Asp Ile  Ile Val 
    2165                 2170                 2175         


<210>  1577
<211>  1154
<212>  PRT
<213>  Homo sapiens

<400>  1577

Met Gln Ala Met Glu Gly Glu Val Leu Leu Pro Ala Leu Tyr Glu Glu 
1               5                   10                  15      


Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Val Glu Glu Glu Glu Glu 
            20                  25                  30          


Gln Val Gln Lys Gly Gly Ser Val Gly Ser Leu Ser Val Asn Lys His 
        35                  40                  45              


Arg Gly Leu Ser Leu Thr Glu Thr Glu Leu Glu Glu Leu Arg Ala Gln 
    50                  55                  60                  


Val Leu Gln Leu Val Ala Glu Leu Glu Glu Thr Arg Glu Leu Ala Gly 
65                  70                  75                  80  


Gln His Glu Asp Asp Ser Leu Glu Leu Gln Gly Leu Leu Glu Asp Glu 
                85                  90                  95      


Arg Leu Ala Ser Ala Gln Gln Ala Glu Val Phe Thr Lys Gln Ile Gln 
            100                 105                 110         


Gln Leu Gln Gly Glu Leu Arg Ser Leu Arg Glu Glu Ile Ser Leu Leu 
        115                 120                 125             


Glu His Glu Lys Glu Ser Glu Leu Lys Glu Ile Glu Gln Glu Leu His 
    130                 135                 140                 


Leu Ala Gln Ala Glu Ile Gln Ser Leu Arg Gln Ala Ala Glu Asp Ser 
145                 150                 155                 160 


Ala Thr Glu His Glu Ser Asp Ile Ala Ser Leu Gln Glu Asp Leu Cys 
                165                 170                 175     


Arg Met Gln Asn Glu Leu Glu Asp Met Glu Arg Ile Arg Gly Asp Tyr 
            180                 185                 190         


Glu Met Glu Ile Ala Ser Leu Arg Ala Glu Met Glu Met Lys Ser Ser 
        195                 200                 205             


Glu Pro Ser Gly Ser Leu Gly Leu Ser Asp Tyr Ser Gly Leu Gln Glu 
    210                 215                 220                 


Glu Leu Gln Glu Leu Arg Glu Arg Tyr His Phe Leu Asn Glu Glu Tyr 
225                 230                 235                 240 


Arg Ala Leu Gln Glu Ser Asn Ser Ser Leu Thr Gly Gln Leu Ala Asp 
                245                 250                 255     


Leu Glu Ser Glu Arg Thr Gln Arg Ala Thr Glu Arg Trp Leu Gln Ser 
            260                 265                 270         


Gln Thr Leu Ser Met Thr Ser Ala Glu Ser Gln Thr Ser Glu Met Asp 
        275                 280                 285             


Phe Leu Glu Pro Asp Pro Glu Met Gln Leu Leu Arg Gln Gln Leu Arg 
    290                 295                 300                 


Asp Ala Glu Glu Gln Met His Gly Met Lys Asn Lys Cys Gln Glu Leu 
305                 310                 315                 320 


Cys Cys Glu Leu Glu Glu Leu Gln His His Arg Gln Val Ser Glu Glu 
                325                 330                 335     


Glu Gln Arg Arg Leu Gln Arg Glu Leu Lys Cys Ala Gln Asn Glu Val 
            340                 345                 350         


Leu Arg Phe Gln Thr Ser His Ser Val Thr Gln Asn Glu Glu Leu Lys 
        355                 360                 365             


Ser Arg Leu Cys Thr Leu Gln Lys Lys Tyr Asp Thr Ser Gln Asp Glu 
    370                 375                 380                 


Gln Asn Glu Leu Leu Lys Met Gln Leu Gln Leu Gln Thr Glu Leu Arg 
385                 390                 395                 400 


Gln Leu Lys Val Met Lys Ser Thr Leu Val Glu Asn Gln Ser Glu Lys 
                405                 410                 415     


Glu Leu Leu Cys Arg Leu Gln Lys Leu His Leu Gln His Gln Asn Val 
            420                 425                 430         


Thr Cys Glu Lys Glu Lys Leu Leu Glu Arg Gln Gln Gln Leu Gln Glu 
        435                 440                 445             


Glu Leu Gln Cys His Glu Ala Glu Leu Gln His Leu Arg Asp Thr Val 
    450                 455                 460                 


Ala Ser Phe Lys Glu Ser Asn Glu Lys Asp Thr Glu Thr His Ala Gln 
465                 470                 475                 480 


Leu Gln Glu Met Lys Gln Leu Tyr Gln Ala Ser Lys Asp Glu Leu Glu 
                485                 490                 495     


Arg Gln Lys His Met Tyr Asp Gln Leu Glu Gln Asp Leu Leu Leu Cys 
            500                 505                 510         


Gln Leu Glu Leu Lys Glu Leu Lys Ala Ser His Pro Ile Pro Glu Asp 
        515                 520                 525             


Lys Gly Lys Cys Ala Asn Lys Cys Asp Thr Leu Leu Ser Arg Leu Thr 
    530                 535                 540                 


Glu Leu Gln Glu Lys Tyr Lys Ala Ser Gln Lys Glu Met Gly Gln Leu 
545                 550                 555                 560 


Gln Met Glu Gln Cys Glu Leu Leu Glu Asp Gln Arg Arg Met Gln Glu 
                565                 570                 575     


Glu Gln Gly Gln Leu Gln Glu Glu Leu His Arg Leu Thr Leu Pro Leu 
            580                 585                 590         


Pro Lys Ser Gly Leu Leu Leu Lys Ser Gln Glu Leu Leu Thr Lys Leu 
        595                 600                 605             


Glu Asp Leu Cys Glu Leu Gln Leu Leu Tyr Gln Gly Met Gln Glu Glu 
    610                 615                 620                 


Gln Lys Lys Leu Ile Gln Asn Gln Asp Cys Val Leu Lys Glu Gln Leu 
625                 630                 635                 640 


Glu Ile His Glu Glu Leu Arg Arg Phe Lys Glu Ser His Phe Gln Glu 
                645                 650                 655     


Val Leu Glu Asn Pro Asp Asp Ser Lys Leu Ala Lys Ser Ser Lys Cys 
            660                 665                 670         


Asn Arg Asn Lys Gln Ser Lys Leu Leu Met Glu Gln Met Gln Ala Leu 
        675                 680                 685             


Gln Val Met Tyr Asp Ala Gly Gln Ala Lys Gln Glu Leu Leu Gln Gln 
    690                 695                 700                 


Glu Gln Gly Arg Leu Leu Glu Glu Arg Lys Arg Leu Gln Ala Asp Leu 
705                 710                 715                 720 


Gln Leu Cys Leu Glu Glu Met Gln Leu Leu Gln Val Gln Ser Pro Ser 
                725                 730                 735     


Ile Lys Met Ser Leu Glu Ser Tyr Gly Lys Ser Tyr Gly Ser Met Val 
            740                 745                 750         


Pro Ser Asn Glu Asn Cys Arg Lys Thr Tyr Asp Thr Thr Val Asp Asp 
        755                 760                 765             


Asn Glu Ser Tyr Tyr Lys Ser Tyr Thr Ser Thr Gln Thr Ser Ser Lys 
    770                 775                 780                 


Ser Phe Leu Lys Ser Tyr Asp Ser Ser Thr Ser Ala Ser Glu Ala Tyr 
785                 790                 795                 800 


Gly Lys Ser Tyr Cys Thr Thr Ser Asn Ser Ser Ile Thr Tyr Lys Lys 
                805                 810                 815     


Ser Tyr Gly Ser Thr Ser Ser Ser Asp Thr Cys Gln Lys Ser Phe Val 
            820                 825                 830         


Ser Ser Cys Thr Asp Glu Glu Pro Ala Glu Pro Glu Asp Met Glu Arg 
        835                 840                 845             


Phe Glu Glu Met Val Val Lys Val Leu Ile Lys Leu Gln Ala Val Gln 
    850                 855                 860                 


Ala Met Tyr Gln Ile Ser Gln Glu Glu His Ser Gln Leu Gln Glu Gln 
865                 870                 875                 880 


Met Glu Lys Leu Leu Ala Lys Gln Lys Asp Leu Lys Glu Glu Leu Asp 
                885                 890                 895     


Ala Cys Glu Arg Glu Phe Lys Glu Cys Met Glu Cys Leu Glu Lys Pro 
            900                 905                 910         


Met Ala Pro Gln Asn Asp Lys Asn Glu Ile Lys Glu Leu Gln Thr Lys 
        915                 920                 925             


Leu Arg Glu Leu Gln Leu Gln Tyr Gln Ala Ser Met Asp Glu Gln Gly 
    930                 935                 940                 


Arg Leu Leu Val Val Gln Glu Gln Leu Glu Gly Gln Leu Gln Cys Cys 
945                 950                 955                 960 


Gln Glu Glu Leu Arg Gln Leu Arg Glu Lys Arg Pro Ser Val Val Lys 
                965                 970                 975     


Glu Ala Arg Gly Lys Asn Ala Asn Lys Asn Met Asn Lys Asn Ala Asn 
            980                 985                 990         


Gly Val Lys Met Lys Lys Val Thr  Lys Pro Cys Ser Asp  Thr Ser Glu 
        995                 1000                 1005             


Ser Asp  Leu Glu Thr Arg Lys  Ser Leu Glu Val Val  Leu Tyr Tyr 
    1010                 1015                 1020             


Lys Ala  Ser Gln Arg Lys Leu  Asp Gly Leu Ala Lys  Glu Glu Glu 
    1025                 1030                 1035             


Lys Lys  Glu Glu Met Glu Glu  Glu Lys Lys Glu Val  Lys Glu Glu 
    1040                 1045                 1050             


Ala Lys  Glu Gln Cys Gly Asp  Glu Leu Val Ala Glu  Pro Ala Asp 
    1055                 1060                 1065             


Pro Glu  Glu Ala Lys Ser Thr  Glu Asp Gln Glu Glu  Asn Glu Glu 
    1070                 1075                 1080             


Asp Lys  Glu Glu Glu Glu Lys  Glu Glu Asp Ser Glu  Glu Glu Glu 
    1085                 1090                 1095             


Asp Asp  Ala Asp Ser Ser Leu  Glu Ser Pro Glu Glu  Asn Asn Pro 
    1100                 1105                 1110             


Leu Arg  Leu Ser Glu Ser Lys  Lys Ser Ser Pro Thr  Pro Asn Pro 
    1115                 1120                 1125             


Pro Ile  Phe Ser Leu Pro Leu  Val Gly Leu Val Val  Ile Ser Ala 
    1130                 1135                 1140             


Leu Leu  Trp Cys Trp Trp Ala  Glu Thr Ser Ser 
    1145                 1150                 


<210>  1578
<211>  2443
<212>  PRT
<213>  Homo sapiens

<400>  1578

Met Ala Ala Glu Glu Gly Val Ala Ser Ala Ala Ser Ala Gly Gly Ser 
1               5                   10                  15      


Trp Gly Thr Ala Ala Met Gly Arg Val Leu Pro Met Leu Leu Val Pro 
            20                  25                  30          


Val Pro Ala Glu Ala Met Gly Gln Leu Gly Ser Arg Ala Gln Leu Arg 
        35                  40                  45              


Thr Gln Pro Glu Ala Leu Gly Ser Leu Thr Ala Ala Gly Ser Leu Gln 
    50                  55                  60                  


Val Leu Ser Leu Thr Pro Gly Ser Arg Gly Gly Gly Arg Cys Cys Leu 
65                  70                  75                  80  


Glu Gly Pro Phe Trp His Phe Leu Trp Glu Asp Ser Arg Asn Ser Ser 
                85                  90                  95      


Thr Pro Thr Glu Lys Pro Lys Leu Leu Ala Leu Gly Glu Asn Tyr Glu 
            100                 105                 110         


Leu Leu Ile Tyr Glu Phe Asn Leu Lys Asp Gly Arg Cys Asp Ala Thr 
        115                 120                 125             


Ile Leu Tyr Ser Cys Ser Arg Glu Ala Leu Gln Lys Leu Ile Asp Asp 
    130                 135                 140                 


Gln Asp Ile Ser Ile Ser Leu Leu Ser Leu Arg Ile Leu Ser Phe His 
145                 150                 155                 160 


Asn Asn Thr Ser Leu Leu Phe Ile Asn Lys Cys Val Ile Leu His Ile 
                165                 170                 175     


Ile Phe Pro Glu Arg Asp Ala Ala Ile Arg Val Leu Asn Cys Phe Thr 
            180                 185                 190         


Leu Pro Leu Pro Ala Gln Ala Val Asp Met Ile Ile Asp Thr Gln Leu 
        195                 200                 205             


Cys Arg Gly Ile Leu Phe Val Leu Ser Ser Leu Gly Trp Ile Tyr Ile 
    210                 215                 220                 


Phe Asp Val Val Asp Gly Thr Tyr Val Ala His Val Asp Leu Ala Leu 
225                 230                 235                 240 


His Lys Glu Asp Met Cys Asn Glu Gln Gln Gln Glu Pro Ala Lys Ile 
                245                 250                 255     


Ser Ser Phe Thr Ser Leu Lys Val Ser Gln Asp Leu Asp Val Ala Val 
            260                 265                 270         


Ile Val Ser Ser Ser Asn Ser Ala Val Ala Leu Asn Leu Asn Leu Tyr 
        275                 280                 285             


Phe Arg Gln His Pro Gly His Leu Leu Cys Glu Arg Ile Leu Glu Asp 
    290                 295                 300                 


Leu Pro Ile Gln Gly Pro Lys Gly Val Asp Glu Asp Asp Pro Val Asn 
305                 310                 315                 320 


Ser Ala Tyr Asn Met Lys Leu Ala Lys Phe Ser Phe Gln Ile Asp Arg 
                325                 330                 335     


Ser Trp Lys Ala Gln Leu Ser Ser Leu Asn Glu Thr Ile Lys Asn Ser 
            340                 345                 350         


Lys Leu Glu Val Ser Cys Cys Ala Pro Trp Phe Gln Asp Ile Leu His 
        355                 360                 365             


Leu Glu Ser Pro Glu Ser Gly Asn His Ser Thr Ser Val Gln Ser Trp 
    370                 375                 380                 


Ala Phe Ile Pro Gln Asp Ile Met His Gly Gln Tyr Asn Val Leu Gln 
385                 390                 395                 400 


Lys Asp His Ala Lys Thr Ser Asp Pro Gly Arg Ser Trp Lys Ile Met 
                405                 410                 415     


His Ile Ser Glu Gln Glu Glu Pro Ile Glu Leu Lys Cys Val Ser Val 
            420                 425                 430         


Thr Gly Phe Thr Ala Leu Phe Thr Trp Glu Val Glu Arg Met Gly Tyr 
        435                 440                 445             


Thr Ile Thr Leu Trp Asp Leu Glu Thr Gln Gly Met Gln Cys Phe Ser 
    450                 455                 460                 


Leu Gly Thr Lys Cys Ile Pro Val Asp Ser Ser Gly Asp Gln Gln Leu 
465                 470                 475                 480 


Cys Phe Val Leu Thr Glu Asn Gly Leu Ser Leu Ile Leu Phe Gly Leu 
                485                 490                 495     


Thr Gln Glu Glu Phe Leu Asn Arg Leu Met Ile His Gly Ser Ala Ser 
            500                 505                 510         


Thr Val Asp Thr Leu Cys His Leu Asn Gly Trp Gly Arg Cys Ser Ile 
        515                 520                 525             


Pro Ile His Ala Leu Glu Ala Gly Ile Glu Asn Arg Gln Leu Asp Thr 
    530                 535                 540                 


Val Asn Phe Phe Leu Lys Ser Lys Glu Asn Leu Phe Asn Pro Ser Ser 
545                 550                 555                 560 


Lys Ser Ser Val Ser Asp Gln Phe Asp His Leu Ser Ser His Leu Tyr 
                565                 570                 575     


Leu Arg Asn Val Glu Glu Leu Ile Pro Ala Leu Asp Leu Leu Cys Ser 
            580                 585                 590         


Ala Ile Arg Glu Ser Tyr Ser Glu Pro Gln Ser Lys His Phe Ser Glu 
        595                 600                 605             


Gln Leu Leu Asn Leu Thr Leu Ser Phe Leu Asn Asn Gln Ile Lys Glu 
    610                 615                 620                 


Leu Phe Ile His Thr Glu Glu Leu Asp Glu His Leu Gln Lys Gly Val 
625                 630                 635                 640 


Asn Ile Leu Thr Ser Tyr Ile Asn Glu Leu Arg Thr Phe Met Ile Lys 
                645                 650                 655     


Phe Pro Trp Lys Leu Thr Asp Ala Ile Asp Glu Tyr Asp Val His Glu 
            660                 665                 670         


Asn Val Pro Lys Val Lys Glu Ser Asn Ile Trp Lys Lys Leu Ser Phe 
        675                 680                 685             


Glu Glu Val Ile Ala Ser Ala Ile Leu Asn Asn Lys Ile Pro Glu Ala 
    690                 695                 700                 


Gln Thr Phe Phe Arg Ile Asp Ser His Ser Ala Gln Lys Leu Glu Glu 
705                 710                 715                 720 


Leu Ile Gly Ile Gly Leu Asn Leu Val Phe Asp Asn Leu Lys Lys Asn 
                725                 730                 735     


Asn Ile Lys Glu Ala Ser Glu Leu Leu Lys Asn Met Gly Phe Asp Val 
            740                 745                 750         


Lys Gly Gln Leu Leu Lys Ile Cys Phe Tyr Thr Thr Asn Lys Asn Ile 
        755                 760                 765             


Arg Asp Phe Leu Val Glu Ile Leu Lys Glu Lys Asn Tyr Phe Ser Glu 
    770                 775                 780                 


Lys Glu Lys Arg Thr Ile Asp Phe Val His Gln Val Glu Lys Leu Tyr 
785                 790                 795                 800 


Leu Gly His Phe Gln Glu Asn Met Gln Ile Gln Ser Phe Pro Arg Tyr 
                805                 810                 815     


Trp Ile Lys Glu Gln Asp Phe Phe Lys His Lys Ser Val Leu Asp Ser 
            820                 825                 830         


Phe Leu Lys Tyr Asp Cys Lys Asp Glu Phe Asn Lys Gln Asp His Arg 
        835                 840                 845             


Ile Val Leu Asn Trp Ala Leu Trp Trp Asp Gln Leu Thr Gln Glu Ser 
    850                 855                 860                 


Ile Leu Leu Pro Arg Ile Ser Pro Glu Glu Tyr Lys Ser Tyr Ser Pro 
865                 870                 875                 880 


Glu Ala Leu Trp Arg Tyr Leu Thr Ala Arg His Asp Trp Leu Asn Ile 
                885                 890                 895     


Ile Leu Trp Ile Gly Glu Phe Gln Thr Gln His Ser Tyr Ala Ser Leu 
            900                 905                 910         


Gln Gln Asn Lys Trp Pro Leu Leu Thr Val Asp Val Ile Asn Gln Asn 
        915                 920                 925             


Thr Ser Cys Asn Asn Tyr Met Arg Asn Glu Ile Leu Asp Lys Leu Ala 
    930                 935                 940                 


Arg Asn Gly Val Phe Leu Ala Ser Glu Leu Glu Asp Phe Glu Cys Phe 
945                 950                 955                 960 


Leu Leu Arg Leu Ser Arg Ile Gly Gly Val Ile Gln Asp Thr Leu Pro 
                965                 970                 975     


Val Gln Asn Tyr Lys Thr Lys Glu Gly Trp Asp Phe His Ser Gln Phe 
            980                 985                 990         


Ile Leu Tyr Cys Leu Glu His Ser  Leu Gln His Leu Leu  Tyr Val Tyr 
        995                 1000                 1005             


Leu Asp  Cys Tyr Lys Leu Ser  Pro Glu Asn Cys Pro  Phe Leu Glu 
    1010                 1015                 1020             


Lys Lys  Glu Leu His Glu Ala  His Pro Trp Phe Glu  Phe Leu Val 
    1025                 1030                 1035             


Gln Cys  Arg Gln Val Ala Ser  Asn Leu Thr Asp Pro  Lys Leu Ile 
    1040                 1045                 1050             


Phe Gln  Ala Ser Leu Ala Asn  Ala Gln Ile Leu Ile  Pro Thr Asn 
    1055                 1060                 1065             


Gln Ala  Ser Val Ser Ser Met  Leu Leu Glu Gly His  Thr Leu Leu 
    1070                 1075                 1080             


Ala Leu  Ala Thr Thr Met Tyr  Ser Pro Gly Gly Val  Ser Gln Val 
    1085                 1090                 1095             


Val Gln  Asn Glu Glu Asn Glu  Asn Cys Leu Lys Lys  Val Asp Pro 
    1100                 1105                 1110             


Gln Leu  Leu Lys Met Ala Leu  Thr Pro Tyr Pro Lys  Leu Lys Thr 
    1115                 1120                 1125             


Ala Leu  Phe Pro Gln Cys Thr  Pro Pro Ser Val Leu  Pro Ser Asp 
    1130                 1135                 1140             


Ile Thr  Ile Tyr His Leu Ile  Gln Ser Leu Ser Pro  Phe Asp Pro 
    1145                 1150                 1155             


Ser Arg  Leu Phe Gly Trp Gln  Ser Ala Asn Thr Leu  Ala Ile Gly 
    1160                 1165                 1170             


Asp Ala  Trp Ser His Leu Pro  His Phe Ser Ser Pro  Asp Leu Val 
    1175                 1180                 1185             


Asn Lys  Tyr Ala Ile Val Glu  Arg Leu Asn Phe Ala  Tyr Tyr Leu 
    1190                 1195                 1200             


His Asn  Gly Arg Pro Ser Phe  Ala Phe Gly Thr Phe  Leu Val Gln 
    1205                 1210                 1215             


Glu Leu  Ile Lys Ser Lys Thr  Pro Lys Gln Leu Ile  Gln Gln Val 
    1220                 1225                 1230             


Gly Asn  Glu Ala Tyr Val Ile  Gly Leu Ser Ser Phe  His Ile Pro 
    1235                 1240                 1245             


Ser Ile  Gly Ala Ala Cys Val  Cys Phe Leu Glu Leu  Leu Gly Leu 
    1250                 1255                 1260             


Asp Ser  Leu Lys Leu Arg Val  Asp Met Lys Val Ala  Asn Ile Ile 
    1265                 1270                 1275             


Leu Ser  Tyr Lys Cys Arg Asn  Glu Asp Ala Gln Tyr  Ser Phe Ile 
    1280                 1285                 1290             


Arg Glu  Ser Val Ala Glu Lys  Leu Ser Lys Leu Ala  Asp Gly Glu 
    1295                 1300                 1305             


Lys Thr  Thr Thr Glu Glu Leu  Leu Val Leu Leu Glu  Glu Gly Thr 
    1310                 1315                 1320             


Trp Asn  Ser Ile Gln Gln Gln  Glu Ile Lys Arg Leu  Ser Ser Glu 
    1325                 1330                 1335             


Ser Ser  Ser Gln Trp Ala Leu  Val Val Gln Phe Cys  Arg Leu His 
    1340                 1345                 1350             


Asn Met  Lys Leu Ser Ile Ser  Tyr Leu Arg Glu Cys  Ala Lys Ala 
    1355                 1360                 1365             


Asn Asp  Trp Leu Gln Phe Ile  Ile His Ser Gln Leu  His Asn Tyr 
    1370                 1375                 1380             


His Pro  Ala Glu Val Lys Ser  Leu Ile Gln Tyr Phe  Ser Pro Val 
    1385                 1390                 1395             


Ile Gln  Asp His Leu Arg Leu  Ala Phe Glu Asn Leu  Pro Ser Val 
    1400                 1405                 1410             


Pro Thr  Ser Lys Met Asp Ser  Asp Gln Val Cys Asn  Lys Cys Pro 
    1415                 1420                 1425             


Gln Glu  Leu Gln Gly Ser Lys  Gln Glu Met Thr Asp  Leu Phe Glu 
    1430                 1435                 1440             


Ile Leu  Leu Gln Cys Ser Glu  Glu Pro Asp Ser Trp  His Trp Leu 
    1445                 1450                 1455             


Leu Val  Glu Ala Val Lys Gln  Gln Ala Pro Ile Leu  Ser Val Leu 
    1460                 1465                 1470             


Ala Ser  Cys Leu Gln Gly Ala  Ser Ala Ile Ser Cys  Leu Cys Val 
    1475                 1480                 1485             


Trp Ile  Ile Thr Ser Val Glu  Asp Asn Val Ala Thr  Glu Ala Met 
    1490                 1495                 1500             


Gly His  Ile Gln Asp Ser Thr  Glu Asp His Thr Trp  Asn Leu Glu 
    1505                 1510                 1515             


Asp Leu  Ser Val Ile Trp Arg  Thr Leu Leu Thr Arg  Gln Lys Ser 
    1520                 1525                 1530             


Lys Thr  Leu Ile Arg Gly Phe  Gln Leu Phe Phe Lys  Asp Ser Pro 
    1535                 1540                 1545             


Leu Leu  Leu Val Met Glu Met  Tyr Glu Leu Cys Met  Phe Phe Arg 
    1550                 1555                 1560             


Asn Tyr  Lys Glu Ala Glu Ala  Lys Leu Leu Glu Phe  Gln Lys Ser 
    1565                 1570                 1575             


Leu Glu  Thr Leu Asn Thr Ala  Ala Thr Lys Val His  Pro Val Ile 
    1580                 1585                 1590             


Pro Ala  Met Trp Leu Glu Asp  Gln Val Cys Phe Leu  Leu Lys Leu 
    1595                 1600                 1605             


Met Leu  Gln Gln Cys Lys Thr  Gln Tyr Glu Leu Gly  Lys Leu Leu 
    1610                 1615                 1620             


Gln Leu  Phe Val Glu Arg Glu  His Leu Phe Ser Asp  Gly Pro Asp 
    1625                 1630                 1635             


Val Lys  Lys Leu Cys Ile Leu  Cys Gln Ile Leu Lys  Asp Thr Ser 
    1640                 1645                 1650             


Ile Ala  Ile Asn His Thr Ile  Ile Thr Ser Tyr Ser  Ile Glu Asn 
    1655                 1660                 1665             


Leu Gln  His Glu Cys Arg Ser  Ile Leu Glu Arg Leu  Gln Thr Asp 
    1670                 1675                 1680             


Gly Gln  Phe Ala Leu Ala Arg  Arg Val Ala Glu Leu  Ala Glu Leu 
    1685                 1690                 1695             


Pro Val  Asp Asn Leu Val Ile  Lys Glu Ile Thr Gln  Glu Met Gln 
    1700                 1705                 1710             


Thr Leu  Lys His Ile Glu Gln  Trp Ser Leu Lys Gln  Ala Arg Ile 
    1715                 1720                 1725             


Asp Phe  Trp Lys Lys Cys His  Glu Asn Phe Lys Lys  Asn Ser Ile 
    1730                 1735                 1740             


Ser Ser  Lys Ala Ala Ser Ser  Phe Phe Ser Thr Gln  Ala His Val 
    1745                 1750                 1755             


Ala Cys  Glu His Pro Thr Gly  Trp Ser Ser Met Glu  Glu Arg His 
    1760                 1765                 1770             


Leu Leu  Leu Thr Leu Ala Gly  His Trp Leu Ala Gln  Glu Asp Val 
    1775                 1780                 1785             


Val Pro  Leu Asp Lys Leu Glu  Glu Leu Glu Lys Gln  Ile Trp Leu 
    1790                 1795                 1800             


Cys Arg  Ile Thr Gln His Thr  Leu Gly Arg Asn Gln  Glu Glu Thr 
    1805                 1810                 1815             


Glu Pro  Arg Phe Ser Arg Gln  Ile Ser Thr Ser Gly  Glu Leu Ser 
    1820                 1825                 1830             


Phe Asp  Ser Leu Ala Ser Glu  Phe Ser Phe Ser Lys  Leu Ala Ala 
    1835                 1840                 1845             


Leu Asn  Thr Ser Lys Tyr Leu  Glu Leu Asn Ser Leu  Pro Ser Lys 
    1850                 1855                 1860             


Glu Thr  Cys Glu Asn Arg Leu  Asp Trp Lys Glu Gln  Glu Ser Leu 
    1865                 1870                 1875             


Asn Phe  Leu Ile Gly Arg Leu  Leu Asp Asp Gly Cys  Val His Glu 
    1880                 1885                 1890             


Ala Ser  Arg Val Cys Arg Tyr  Phe His Phe Tyr Asn  Pro Asp Val 
    1895                 1900                 1905             


Ala Leu  Val Leu His Cys Arg  Ala Leu Ala Ser Gly  Glu Ala Ser 
    1910                 1915                 1920             


Met Glu  Asp Leu His Pro Glu  Ile His Ala Leu Leu  Gln Ser Ala 
    1925                 1930                 1935             


Glu Leu  Leu Glu Glu Glu Ala  Pro Asp Ile Pro Leu  Arg Arg Val 
    1940                 1945                 1950             


His Ser  Thr Ser Ser Leu Asp  Ser Gln Lys Phe Val  Thr Val Pro 
    1955                 1960                 1965             


Ser Ser  Asn Glu Val Val Thr  Asn Leu Glu Val Leu  Thr Ser Lys 
    1970                 1975                 1980             


Cys Leu  His Gly Lys Asn Tyr  Cys Arg Gln Val Leu  Cys Leu Tyr 
    1985                 1990                 1995             


Asp Leu  Ala Lys Glu Leu Gly  Cys Ser Tyr Thr Asp  Val Ala Ala 
    2000                 2005                 2010             


Gln Asp  Gly Glu Ala Met Leu  Arg Lys Ile Leu Ala  Ser Gln Gln 
    2015                 2020                 2025             


Pro Asp  Arg Cys Lys Arg Ala  Gln Ala Phe Ile Ser  Thr Gln Gly 
    2030                 2035                 2040             


Leu Lys  Pro Asp Thr Val Ala  Glu Leu Val Ala Glu  Glu Val Thr 
    2045                 2050                 2055             


Arg Glu  Leu Leu Thr Ser Ser  Gln Gly Thr Gly His  Lys Gln Met 
    2060                 2065                 2070             


Phe Asn  Pro Thr Glu Glu Ser  Gln Thr Phe Leu Gln  Leu Thr Thr 
    2075                 2080                 2085             


Leu Cys  Gln Asp Arg Thr Leu  Val Gly Met Lys Leu  Leu Asp Lys 
    2090                 2095                 2100             


Ile Ser  Ser Val Pro His Gly  Glu Leu Ser Cys Thr  Thr Glu Leu 
    2105                 2110                 2115             


Leu Ile  Leu Ala His His Cys  Phe Thr Leu Thr Cys  His Met Glu 
    2120                 2125                 2130             


Gly Ile  Ile Arg Val Leu Gln  Ala Ala His Met Leu  Thr Asp Asn 
    2135                 2140                 2145             


His Leu  Ala Pro Ser Glu Glu  Tyr Gly Leu Val Val  Arg Leu Leu 
    2150                 2155                 2160             


Thr Gly  Ile Gly Arg Tyr Asn  Glu Met Thr Tyr Ile  Phe Asp Leu 
    2165                 2170                 2175             


Leu His  Lys Lys His Tyr Phe  Glu Val Leu Met Arg  Lys Lys Leu 
    2180                 2185                 2190             


Asp Pro  Ser Gly Thr Leu Lys  Thr Ala Leu Leu Asp  Tyr Ile Lys 
    2195                 2200                 2205             


Arg Cys  Arg Pro Gly Asp Ser  Glu Lys His Asn Met  Ile Ala Leu 
    2210                 2215                 2220             


Cys Phe  Ser Met Cys Arg Glu  Ile Gly Glu Asn His  Glu Ala Ala 
    2225                 2230                 2235             


Ala Arg  Ile Gln Leu Lys Leu  Ile Glu Ser Gln Pro  Trp Glu Asp 
    2240                 2245                 2250             


Ser Leu  Lys Asp Gly His Gln  Leu Lys Gln Leu Leu  Leu Lys Ala 
    2255                 2260                 2265             


Leu Thr  Leu Met Leu Asp Ala  Ala Glu Ser Tyr Ala  Lys Asp Ser 
    2270                 2275                 2280             


Cys Val  Arg Gln Ala Gln His  Cys Gln Arg Leu Thr  Lys Leu Ile 
    2285                 2290                 2295             


Thr Leu  Gln Ile His Phe Leu  Asn Thr Gly Gln Asn  Thr Met Leu 
    2300                 2305                 2310             


Ile Asn  Leu Gly Arg His Lys  Leu Met Asp Cys Ile  Leu Ala Leu 
    2315                 2320                 2325             


Pro Arg  Phe Tyr Gln Ala Ser  Ile Val Ala Glu Ala  Tyr Asp Phe 
    2330                 2335                 2340             


Val Pro  Asp Trp Ala Glu Ile  Leu Tyr Gln Gln Val  Ile Leu Lys 
    2345                 2350                 2355             


Gly Asp  Phe Asn Tyr Leu Glu  Glu Phe Lys Gln Gln  Arg Leu Leu 
    2360                 2365                 2370             


Lys Ser  Ser Ile Phe Glu Glu  Ile Ser Lys Lys Tyr  Lys Gln His 
    2375                 2380                 2385             


Gln Pro  Thr Asp Met Val Met  Glu Asn Leu Lys Lys  Leu Leu Thr 
    2390                 2395                 2400             


Tyr Cys  Glu Asp Val Tyr Leu  Tyr Tyr Lys Leu Ala  Tyr Glu His 
    2405                 2410                 2415             


Lys Phe  Tyr Glu Ile Val Asn  Val Leu Leu Lys Asp  Pro Gln Thr 
    2420                 2425                 2430             


Gly Cys  Cys Leu Lys Asp Met  Leu Ala Gly 
    2435                 2440             


<210>  1579
<211>  648
<212>  PRT
<213>  Homo sapiens

<400>  1579

Met Ser Trp Leu Phe Gly Val Asn Lys Gly Pro Lys Gly Glu Gly Ala 
1               5                   10                  15      


Gly Pro Pro Pro Pro Leu Pro Pro Ala Gln Pro Gly Ala Glu Gly Gly 
            20                  25                  30          


Gly Asp Arg Gly Leu Gly Asp Arg Pro Ala Pro Lys Asp Lys Trp Ser 
        35                  40                  45              


Asn Phe Asp Pro Thr Gly Leu Glu Arg Ala Ala Lys Ala Ala Arg Glu 
    50                  55                  60                  


Leu Glu His Ser Arg Tyr Ala Lys Glu Ala Leu Asn Leu Ala Gln Met 
65                  70                  75                  80  


Gln Glu Gln Thr Leu Gln Leu Glu Gln Gln Ser Lys Leu Lys Glu Tyr 
                85                  90                  95      


Glu Ala Ala Val Glu Gln Leu Lys Ser Glu Gln Ile Arg Ala Gln Ala 
            100                 105                 110         


Glu Glu Arg Arg Lys Thr Leu Ser Glu Glu Thr Arg Gln His Gln Ala 
        115                 120                 125             


Arg Ala Gln Tyr Gln Asp Lys Leu Ala Arg Gln Arg Tyr Glu Asp Gln 
    130                 135                 140                 


Leu Lys Gln Gln Gln Leu Leu Asn Glu Glu Asn Leu Arg Lys Gln Glu 
145                 150                 155                 160 


Glu Ser Val Gln Lys Gln Glu Ala Met Arg Arg Ala Thr Val Glu Arg 
                165                 170                 175     


Glu Met Glu Leu Arg His Lys Asn Glu Met Leu Arg Val Glu Thr Glu 
            180                 185                 190         


Ala Arg Ala Arg Ala Lys Ala Glu Arg Glu Asn Ala Asp Ile Ile Arg 
        195                 200                 205             


Glu Gln Ile Arg Leu Lys Ala Ser Glu His Arg Gln Thr Val Leu Glu 
    210                 215                 220                 


Ser Ile Arg Thr Ala Gly Thr Leu Phe Gly Glu Gly Phe Arg Ala Phe 
225                 230                 235                 240 


Val Thr Asp Arg Asp Lys Val Thr Ala Thr Val Ala Gly Leu Thr Leu 
                245                 250                 255     


Leu Ala Val Gly Val Tyr Ser Ala Lys Asn Ala Thr Ala Val Thr Gly 
            260                 265                 270         


Arg Phe Ile Glu Ala Arg Leu Gly Lys Pro Ser Leu Val Arg Glu Thr 
        275                 280                 285             


Ser Arg Ile Thr Val Leu Glu Ala Leu Arg His Pro Ile Gln Val Ser 
    290                 295                 300                 


Arg Arg Leu Leu Ser Arg Pro Gln Asp Val Leu Glu Gly Val Val Leu 
305                 310                 315                 320 


Ser Pro Ser Leu Glu Ala Arg Val Arg Asp Ile Ala Ile Ala Thr Arg 
                325                 330                 335     


Asn Thr Lys Lys Asn Arg Gly Leu Tyr Arg His Ile Leu Leu Tyr Gly 
            340                 345                 350         


Pro Pro Gly Thr Gly Lys Thr Leu Phe Ala Lys Lys Leu Ala Leu His 
        355                 360                 365             


Ser Gly Met Asp Tyr Ala Ile Met Thr Gly Gly Asp Val Ala Pro Met 
    370                 375                 380                 


Gly Arg Glu Gly Val Thr Ala Met His Lys Leu Phe Asp Trp Ala Asn 
385                 390                 395                 400 


Thr Ser Arg Arg Gly Leu Leu Leu Phe Met Asp Glu Ala Asp Ala Phe 
                405                 410                 415     


Leu Arg Lys Arg Ala Thr Glu Glu Ile Ser Lys Asp Leu Arg Ala Thr 
            420                 425                 430         


Leu Asn Ala Phe Leu Tyr His Met Gly Gln His Ser Asn Lys Phe Met 
        435                 440                 445             


Leu Val Leu Ala Ser Asn Leu Pro Glu Gln Phe Asp Cys Ala Ile Asn 
    450                 455                 460                 


Ser Arg Ile Asp Val Met Val His Phe Asp Leu Pro Gln Gln Glu Glu 
465                 470                 475                 480 


Arg Glu Arg Leu Val Arg Leu His Phe Asp Asn Cys Val Leu Lys Pro 
                485                 490                 495     


Ala Thr Glu Gly Lys Arg Arg Leu Lys Leu Ala Gln Phe Asp Tyr Gly 
            500                 505                 510         


Arg Lys Cys Ser Glu Val Ala Arg Leu Thr Glu Gly Met Ser Gly Arg 
        515                 520                 525             


Glu Ile Ala Gln Leu Ala Val Ser Trp Gln Ala Thr Ala Tyr Ala Ser 
    530                 535                 540                 


Lys Asp Gly Val Leu Thr Glu Ala Met Met Asp Ala Cys Val Gln Asp 
545                 550                 555                 560 


Ala Val Gln Gln Tyr Arg Gln Lys Met Arg Trp Leu Lys Ala Glu Gly 
                565                 570                 575     


Pro Gly Arg Gly Val Glu His Pro Leu Ser Gly Val Gln Gly Glu Thr 
            580                 585                 590         


Leu Thr Ser Trp Ser Leu Ala Thr Asp Pro Ser Tyr Pro Cys Leu Ala 
        595                 600                 605             


Gly Pro Cys Thr Phe Arg Ile Cys Ser Trp Met Gly Thr Gly Leu Cys 
    610                 615                 620                 


Pro Gly Pro Leu Ser Pro Arg Met Ser Cys Gly Gly Gly Arg Pro Phe 
625                 630                 635                 640 


Cys Pro Pro Gly His Pro Leu Leu 
                645             


<210>  1580
<211>  1043
<212>  PRT
<213>  Homo sapiens

<400>  1580

Met Arg Arg Phe Lys Arg Lys His Leu Thr Ala Ile Asp Cys Gln His 
1               5                   10                  15      


Leu Ala Arg Ser His Leu Ala Val Thr Gln Pro Phe Gly Gln Arg Trp 
            20                  25                  30          


Thr Asn Arg Asp Pro Asn His Gly Leu Tyr Pro Lys Pro Arg Thr Lys 
        35                  40                  45              


Arg Gly Ser Arg Gly Gln Gly Ser Gln Arg Cys Ile Pro Glu Phe Phe 
    50                  55                  60                  


Leu Ala Gly Lys Gln Pro Cys Thr Asn Asp Met Ala Lys Ser Asn Ser 
65                  70                  75                  80  


Val Gly Gln Asp Ser Cys Gln Asp Ser Glu Gly Asp Met Ile Phe Pro 
                85                  90                  95      


Ala Glu Ser Ser Cys Ala Leu Pro Gln Glu Gly Ser Ala Gly Pro Gly 
            100                 105                 110         


Ser Pro Gly Ser Ala Pro Pro Ser Arg Lys Arg Ser Trp Ser Ser Glu 
        115                 120                 125             


Glu Glu Ser Asn Gln Ala Thr Gly Thr Ser Arg Trp Asp Gly Val Ser 
    130                 135                 140                 


Lys Lys Ala Pro Arg His His Leu Ser Val Pro Cys Thr Arg Pro Arg 
145                 150                 155                 160 


Glu Ala Arg Gln Glu Ala Glu Asp Ser Thr Ser Arg Leu Ser Ala Glu 
                165                 170                 175     


Ser Gly Glu Thr Asp Gln Asp Ala Gly Asp Val Gly Pro Asp Pro Ile 
            180                 185                 190         


Pro Asp Ser Tyr Tyr Gly Leu Leu Gly Thr Leu Pro Cys Gln Glu Ala 
        195                 200                 205             


Leu Ser His Ile Cys Ser Leu Pro Ser Glu Val Leu Arg His Val Phe 
    210                 215                 220                 


Ala Phe Leu Pro Val Glu Asp Leu Tyr Trp Asn Leu Ser Leu Val Cys 
225                 230                 235                 240 


His Leu Trp Arg Glu Ile Ile Ser Asp Pro Leu Phe Ile Pro Trp Lys 
                245                 250                 255     


Lys Leu Tyr His Arg Tyr Leu Met Asn Glu Glu Gln Ala Val Ser Lys 
            260                 265                 270         


Val Asp Gly Ile Leu Ser Asn Cys Gly Ile Glu Lys Glu Ser Asp Leu 
        275                 280                 285             


Cys Val Leu Asn Leu Ile Arg Tyr Thr Ala Thr Thr Lys Cys Ser Pro 
    290                 295                 300                 


Ser Val Asp Pro Glu Arg Val Leu Trp Ser Leu Arg Asp His Pro Leu 
305                 310                 315                 320 


Leu Pro Glu Ala Glu Ala Cys Val Arg Gln His Leu Pro Asp Leu Tyr 
                325                 330                 335     


Ala Ala Ala Gly Gly Val Asn Ile Trp Ala Leu Val Ala Ala Val Val 
            340                 345                 350         


Leu Leu Ser Ser Ser Val Asn Asp Ile Gln Arg Leu Leu Phe Cys Leu 
        355                 360                 365             


Arg Arg Pro Ser Ser Thr Val Thr Met Pro Asp Val Thr Glu Thr Leu 
    370                 375                 380                 


Tyr Cys Ile Ala Val Leu Leu Tyr Ala Met Arg Glu Lys Gly Ile Asn 
385                 390                 395                 400 


Ile Ser Asn Arg Ile His Tyr Asn Ile Phe Tyr Cys Leu Tyr Leu Gln 
                405                 410                 415     


Glu Asn Ser Cys Thr Gln Ala Thr Lys Val Lys Glu Glu Pro Ser Val 
            420                 425                 430         


Trp Pro Gly Lys Lys Thr Ile Gln Leu Thr His Glu Gln Gln Leu Ile 
        435                 440                 445             


Leu Asn His Lys Met Glu Pro Leu Gln Val Val Lys Ile Met Ala Phe 
    450                 455                 460                 


Ala Gly Thr Gly Lys Thr Ser Thr Leu Val Lys Tyr Ala Glu Lys Trp 
465                 470                 475                 480 


Ser Gln Ser Arg Phe Leu Tyr Val Thr Phe Asn Lys Ser Ile Ala Lys 
                485                 490                 495     


Gln Ala Glu Arg Val Phe Pro Ser Asn Val Ile Cys Lys Thr Phe His 
            500                 505                 510         


Ser Met Ala Tyr Gly His Ile Gly Arg Lys Tyr Gln Ser Lys Lys Lys 
        515                 520                 525             


Leu Asn Leu Phe Lys Leu Thr Pro Phe Met Val Asn Ser Val Leu Ala 
    530                 535                 540                 


Glu Gly Lys Gly Gly Phe Ile Arg Ala Lys Leu Val Cys Lys Thr Leu 
545                 550                 555                 560 


Glu Asn Phe Phe Ala Ser Ala Asp Glu Glu Leu Thr Ile Asp His Val 
                565                 570                 575     


Pro Ile Trp Cys Lys Asn Ser Gln Gly Gln Arg Val Met Val Glu Gln 
            580                 585                 590         


Ser Glu Lys Leu Asn Gly Val Leu Glu Ala Ser Arg Leu Trp Asp Asn 
        595                 600                 605             


Met Arg Lys Leu Gly Glu Cys Thr Glu Glu Ala His Gln Met Thr His 
    610                 615                 620                 


Asp Gly Tyr Leu Lys Leu Trp Gln Leu Ser Lys Pro Ser Leu Ala Ser 
625                 630                 635                 640 


Phe Asp Ala Ile Phe Val Asp Glu Ala Gln Asp Cys Thr Pro Ala Ile 
                645                 650                 655     


Met Asn Ile Val Leu Ser Gln Pro Cys Gly Lys Ile Phe Val Gly Asp 
            660                 665                 670         


Pro His Gln Gln Ile Tyr Thr Phe Arg Gly Ala Val Asn Ala Leu Phe 
        675                 680                 685             


Thr Val Pro His Thr His Val Phe Tyr Leu Thr Gln Ser Phe Arg Phe 
    690                 695                 700                 


Gly Val Glu Ile Ala Tyr Val Gly Ala Thr Ile Leu Asp Val Cys Lys 
705                 710                 715                 720 


Arg Val Arg Lys Lys Thr Leu Val Gly Gly Asn His Gln Ser Gly Ile 
                725                 730                 735     


Arg Gly Asp Ala Lys Gly Gln Val Ala Leu Leu Ser Arg Thr Asn Ala 
            740                 745                 750         


Asn Val Phe Asp Glu Ala Val Arg Val Thr Glu Gly Glu Phe Pro Ser 
        755                 760                 765             


Arg Ile His Leu Ile Gly Gly Ile Lys Ser Phe Gly Leu Asp Arg Ile 
    770                 775                 780                 


Ile Asp Ile Trp Ile Leu Leu Gln Pro Glu Glu Glu Arg Arg Lys Gln 
785                 790                 795                 800 


Asn Leu Val Ile Lys Asp Lys Phe Ile Arg Arg Trp Val His Lys Glu 
                805                 810                 815     


Gly Phe Ser Gly Phe Lys Arg Tyr Val Thr Ala Ala Glu Asp Lys Glu 
            820                 825                 830         


Leu Glu Ala Lys Ile Ala Val Val Glu Lys Tyr Asn Ile Arg Ile Pro 
        835                 840                 845             


Glu Leu Val Gln Arg Ile Glu Lys Cys His Ile Glu Asp Leu Asp Phe 
    850                 855                 860                 


Ala Glu Tyr Ile Leu Gly Thr Val His Lys Ala Lys Gly Leu Glu Phe 
865                 870                 875                 880 


Asp Thr Val His Val Leu Asp Asp Phe Val Lys Val Pro Cys Ala Arg 
                885                 890                 895     


His Asn Leu Pro Gln Leu Pro His Phe Arg Val Glu Ser Phe Ser Glu 
            900                 905                 910         


Asp Glu Trp Asn Leu Leu Tyr Val Ala Val Thr Arg Ala Lys Lys Arg 
        915                 920                 925             


Leu Ile Met Thr Lys Ser Leu Glu Asn Ile Leu Thr Leu Ala Gly Glu 
    930                 935                 940                 


Tyr Phe Leu Gln Ala Glu Leu Thr Ser Asn Val Leu Lys Thr Gly Val 
945                 950                 955                 960 


Val Arg Cys Cys Val Gly Gln Cys Asn Asn Ala Ile Pro Val Asp Thr 
                965                 970                 975     


Val Leu Thr Met Lys Lys Leu Pro Ile Thr Tyr Ser Asn Arg Lys Glu 
            980                 985                 990         


Asn Lys Gly Gly Tyr Leu Cys His  Ser Cys Ala Glu Gln  Arg Ile Gly 
        995                 1000                 1005             


Pro Leu  Ala Phe Leu Thr Ala  Ser Pro Glu Gln Val  Arg Ala Met 
    1010                 1015                 1020             


Glu Arg  Thr Val Glu Asn Ile  Val Leu Pro Arg His  Glu Ala Leu 
    1025                 1030                 1035             


Leu Phe  Leu Val Phe 
    1040             


<210>  1581
<211>  885
<212>  PRT
<213>  Homo sapiens

<400>  1581

Met Ser His Pro Asp Tyr Arg Met Asn Leu Arg Pro Leu Gly Thr Pro 
1               5                   10                  15      


Arg Gly Val Ser Ala Val Ala Gly Pro His Asp Ile Gly Ala Ser Pro 
            20                  25                  30          


Gly Asp Lys Lys Ser Lys Asn Arg Ser Thr Arg Gly Lys Lys Lys Ser 
        35                  40                  45              


Ile Phe Glu Thr Tyr Met Ser Lys Glu Asp Val Ser Glu Gly Leu Lys 
    50                  55                  60                  


Arg Gly Thr Leu Ile Gln Gly Val Leu Arg Ile Asn Pro Lys Lys Phe 
65                  70                  75                  80  


His Glu Ala Phe Ile Pro Ser Pro Asp Gly Asp Arg Asp Ile Phe Ile 
                85                  90                  95      


Asp Gly Val Val Ala Arg Asn Arg Ala Leu Asn Gly Asp Leu Val Val 
            100                 105                 110         


Val Lys Leu Leu Pro Glu Glu His Trp Lys Val Val Lys Pro Glu Ser 
        115                 120                 125             


Asn Asp Lys Glu Thr Glu Ala Ala Tyr Glu Ser Asp Ile Pro Glu Glu 
    130                 135                 140                 


Leu Cys Gly His His Leu Pro Gln Gln Ser Leu Lys Ser Tyr Asn Asp 
145                 150                 155                 160 


Ser Pro Asp Val Ile Val Glu Ala Gln Phe Asp Gly Ser Asp Ser Glu 
                165                 170                 175     


Asp Gly His Gly Ile Thr Gln Asn Val Leu Val Asp Gly Val Lys Lys 
            180                 185                 190         


Leu Ser Val Cys Val Ser Glu Lys Gly Arg Glu Asp Gly Asp Ala Pro 
        195                 200                 205             


Val Thr Lys Asp Glu Thr Thr Cys Ile Ser Gln Asp Thr Arg Ala Leu 
    210                 215                 220                 


Ser Glu Lys Ser Leu Gln Arg Ser Ala Lys Val Val Tyr Ile Leu Glu 
225                 230                 235                 240 


Lys Lys His Ser Arg Ala Ala Thr Gly Phe Leu Lys Leu Leu Ala Asp 
                245                 250                 255     


Lys Asn Ser Glu Leu Phe Arg Lys Tyr Ala Leu Phe Ser Pro Ser Asp 
            260                 265                 270         


His Arg Val Pro Arg Ile Tyr Val Pro Leu Lys Asp Cys Pro Gln Asp 
        275                 280                 285             


Phe Val Ala Arg Pro Lys Asp Tyr Ala Asn Thr Leu Phe Ile Cys Arg 
    290                 295                 300                 


Ile Val Asp Trp Lys Glu Asp Cys Asn Phe Ala Leu Gly Gln Leu Ala 
305                 310                 315                 320 


Lys Ser Leu Gly Gln Ala Gly Glu Ile Glu Pro Glu Thr Glu Gly Ile 
                325                 330                 335     


Leu Thr Glu Tyr Gly Val Asp Phe Ser Asp Phe Ser Ser Glu Val Leu 
            340                 345                 350         


Glu Cys Leu Pro Gln Gly Leu Pro Trp Thr Ile Pro Pro Glu Glu Phe 
        355                 360                 365             


Ser Lys Arg Arg Asp Leu Arg Lys Asp Cys Ile Phe Thr Ile Asp Pro 
    370                 375                 380                 


Ser Thr Ala Arg Asp Leu Asp Asp Ala Leu Ser Cys Lys Pro Leu Ala 
385                 390                 395                 400 


Asp Gly Asn Phe Lys Val Gly Val His Ile Ala Asp Val Ser Tyr Phe 
                405                 410                 415     


Val Pro Glu Gly Ser Asp Leu Asp Lys Val Ala Ala Glu Arg Ala Thr 
            420                 425                 430         


Ser Val Tyr Leu Val Gln Lys Val Val Pro Met Leu Pro Arg Leu Leu 
        435                 440                 445             


Cys Glu Glu Leu Cys Ser Leu Asn Pro Met Ser Asp Lys Leu Thr Phe 
    450                 455                 460                 


Ser Val Ile Trp Thr Leu Thr Pro Glu Gly Lys Ile Leu Asp Glu Trp 
465                 470                 475                 480 


Phe Gly Arg Thr Ile Ile Arg Ser Cys Thr Lys Leu Ser Tyr Glu His 
                485                 490                 495     


Ala Gln Ser Met Ile Glu Ser Pro Thr Glu Lys Ile Pro Ala Lys Glu 
            500                 505                 510         


Leu Pro Pro Ile Ser Pro Glu His Ser Ser Glu Glu Val His Gln Ala 
        515                 520                 525             


Val Leu Asn Leu His Gly Ile Ala Lys Gln Leu Arg Gln Gln Arg Phe 
    530                 535                 540                 


Val Asp Gly Ala Leu Arg Leu Asp Gln Leu Lys Leu Ala Phe Thr Leu 
545                 550                 555                 560 


Asp His Glu Thr Gly Leu Pro Gln Gly Cys His Ile Tyr Glu Tyr Arg 
                565                 570                 575     


Glu Ser Asn Lys Leu Val Glu Glu Phe Met Leu Leu Ala Asn Met Ala 
            580                 585                 590         


Val Ala His Lys Ile His Arg Ala Phe Pro Glu Gln Ala Leu Leu Arg 
        595                 600                 605             


Arg His Pro Pro Pro Gln Thr Arg Met Leu Ser Asp Leu Val Glu Phe 
    610                 615                 620                 


Cys Asp Gln Met Gly Leu Pro Val Asp Phe Ser Ser Ala Gly Ala Leu 
625                 630                 635                 640 


Asn Lys Ser Leu Thr Gln Thr Phe Gly Asp Asp Lys Tyr Ser Leu Ala 
                645                 650                 655     


Arg Lys Glu Val Leu Thr Asn Met Cys Ser Arg Pro Met Gln Met Ala 
            660                 665                 670         


Leu Tyr Phe Cys Ser Gly Leu Leu Gln Asp Pro Ala Gln Phe Arg His 
        675                 680                 685             


Tyr Ala Leu Asn Val Pro Leu Tyr Thr His Phe Thr Ser Pro Ile Arg 
    690                 695                 700                 


Arg Phe Ala Asp Val Leu Val His Arg Leu Leu Ala Ala Ala Leu Gly 
705                 710                 715                 720 


Tyr Arg Glu Arg Leu Asp Met Ala Pro Asp Thr Leu Gln Lys Gln Ala 
                725                 730                 735     


Asp His Cys Asn Asp Arg Arg Met Ala Ser Lys Arg Val Gln Glu Leu 
            740                 745                 750         


Ser Thr Ser Leu Phe Phe Ala Val Leu Val Lys Glu Ser Gly Pro Leu 
        755                 760                 765             


Glu Ser Glu Ala Met Val Met Gly Ile Leu Lys Gln Ala Phe Asp Val 
    770                 775                 780                 


Leu Val Leu Arg Tyr Gly Val Gln Lys Arg Ile Tyr Cys Asn Ala Leu 
785                 790                 795                 800 


Ala Leu Arg Ser His His Phe Gln Lys Val Gly Lys Lys Pro Glu Leu 
                805                 810                 815     


Thr Leu Val Trp Glu Pro Glu Asp Met Glu Gln Glu Pro Ala Gln Gln 
            820                 825                 830         


Val Ile Thr Ile Phe Ser Leu Val Glu Val Val Leu Gln Ala Glu Ser 
        835                 840                 845             


Thr Ala Leu Lys Tyr Ser Ala Ile Leu Lys Arg Pro Gly Thr Gln Gly 
    850                 855                 860                 


His Leu Gly Pro Glu Lys Glu Glu Glu Glu Ser Asp Gly Glu Pro Glu 
865                 870                 875                 880 


Asp Ser Ser Thr Ser 
                885 


<210>  1582
<211>  381
<212>  PRT
<213>  Homo sapiens

<400>  1582

Met Ala Leu Lys Ala Glu Gly Ala Ala Leu Asp Cys Phe Glu Val Thr 
1               5                   10                  15      


Leu Lys Cys Glu Glu Gly Glu Asp Glu Glu Glu Ala Met Val Val Ala 
            20                  25                  30          


Val Ile Pro Arg Pro Glu Pro Met Leu Arg Val Thr Gln Gln Glu Lys 
        35                  40                  45              


Thr Pro Pro Pro Arg Pro Ser Pro Leu Glu Ala Gly Ser Asp Gly Cys 
    50                  55                  60                  


Glu Glu Pro Lys Gln Gln Val Ser Trp Glu Gln Glu Phe Leu Val Gly 
65                  70                  75                  80  


Ser Ser Pro Gly Gly Ser Gly Arg Ala Leu Cys Met Val Cys Gly Ala 
                85                  90                  95      


Glu Ile Arg Ala Pro Ser Ala Asp Thr Ala Arg Ser His Ile Leu Glu 
            100                 105                 110         


Gln His Pro His Thr Leu Asp Leu Ser Pro Ser Glu Lys Ser Asn Ile 
        115                 120                 125             


Leu Glu Ala Trp Ser Glu Gly Val Ala Leu Leu Gln Asp Val Arg Ala 
    130                 135                 140                 


Glu Gln Pro Ser Pro Pro Asn Ser Asp Ser Gly Gln Asp Ala His Pro 
145                 150                 155                 160 


Asp Pro Asp Ala Asn Pro Asp Ala Ala Arg Met Pro Ala Glu Ile Val 
                165                 170                 175     


Val Leu Leu Asp Ser Glu Asp Asn Pro Ser Leu Pro Lys Arg Ser Arg 
            180                 185                 190         


Pro Arg Gly Leu Arg Pro Leu Glu Leu Pro Ala Val Pro Ala Thr Glu 
        195                 200                 205             


Pro Gly Asn Lys Lys Pro Arg Gly Gln Arg Trp Lys Glu Pro Pro Gly 
    210                 215                 220                 


Glu Glu Pro Val Arg Lys Lys Arg Gly Arg Pro Met Thr Lys Asn Leu 
225                 230                 235                 240 


Asp Pro Asp Pro Glu Pro Pro Ser Pro Asp Ser Pro Thr Glu Thr Phe 
                245                 250                 255     


Ala Ala Pro Ala Glu Val Arg His Phe Thr Asp Gly Ser Phe Pro Ala 
            260                 265                 270         


Gly Phe Val Leu Gln Leu Phe Ser His Thr Gln Leu Arg Gly Pro Asp 
        275                 280                 285             


Ser Lys Asp Ser Pro Lys Asp Arg Glu Val Ala Glu Gly Gly Leu Pro 
    290                 295                 300                 


Arg Ala Glu Ser Pro Ser Pro Ala Pro Pro Pro Gly Leu Arg Gly Thr 
305                 310                 315                 320 


Leu Asp Leu Gln Val Ile Arg Val Arg Met Glu Glu Pro Pro Ala Val 
                325                 330                 335     


Ser Leu Leu Gln Asp Trp Ser Arg His Pro Gln Gly Thr Lys Arg Val 
            340                 345                 350         


Gly Ala Gly Asp Thr Ser Asp Trp Pro Thr Val Leu Ser Glu Ser Ser 
        355                 360                 365             


Thr Thr Val Ala Gly Lys Pro Glu Lys Gly Asn Gly Val 
    370                 375                 380     


<210>  1583
<211>  896
<212>  PRT
<213>  Homo sapiens

<400>  1583

Met Asp Gly Ala Ala Gly Pro Gly Asp Gly Pro Ala Arg Glu Ala Leu 
1               5                   10                  15      


Gln Ser Leu Ser Gln Arg Leu Arg Val Gln Glu Gln Glu Met Glu Leu 
            20                  25                  30          


Val Lys Ala Ala Leu Ala Glu Ala Leu Arg Leu Leu Arg Leu Gln Val 
        35                  40                  45              


Pro Pro Ser Ser Leu Gln Gly Ser Gly Thr Pro Ala Pro Pro Gly Asp 
    50                  55                  60                  


Ser Leu Ala Ala Pro Pro Gly Leu Pro Pro Thr Cys Thr Pro Ser Leu 
65                  70                  75                  80  


Val Ser Arg Gly Thr Gln Thr Glu Thr Glu Val Glu Leu Lys Ser Ser 
                85                  90                  95      


Pro Gly Pro Pro Gly Leu Ser Asn Gly Pro Pro Ala Pro Gln Gly Ala 
            100                 105                 110         


Ser Glu Glu Pro Ser Gly Thr Gln Ser Glu Gly Gly Gly Ser Ser Ser 
        115                 120                 125             


Ser Gly Ala Gly Ser Pro Gly Pro Pro Gly Ile Leu Arg Pro Leu Gln 
    130                 135                 140                 


Pro Pro Gln Arg Ala Asp Thr Pro Arg Arg Asn Ser Ser Ser Ser Ser 
145                 150                 155                 160 


Ser Pro Ser Glu Arg Pro Arg Gln Lys Leu Ser Arg Lys Ala Ile Ser 
                165                 170                 175     


Ser Ala Asn Leu Leu Val Arg Ser Gly Ser Thr Glu Ser Arg Gly Gly 
            180                 185                 190         


Lys Asp Pro Leu Ser Ser Pro Gly Gly Pro Gly Ser Arg Arg Ser Asn 
        195                 200                 205             


Tyr Asn Leu Glu Gly Ile Ser Val Lys Met Phe Leu Arg Gly Arg Pro 
    210                 215                 220                 


Ile Thr Met Tyr Ile Pro Ser Gly Ile Arg Ser Leu Glu Glu Leu Pro 
225                 230                 235                 240 


Ser Gly Pro Pro Pro Glu Thr Leu Ser Leu Asp Trp Val Tyr Gly Tyr 
                245                 250                 255     


Arg Gly Arg Asp Ser Arg Ser Asn Leu Phe Val Leu Arg Ser Gly Glu 
            260                 265                 270         


Val Val Tyr Phe Ile Ala Cys Val Val Val Leu Tyr Arg Pro Gly Gly 
        275                 280                 285             


Gly Pro Gly Gly Pro Gly Gly Gly Gly Gln Arg His Tyr Arg Gly His 
    290                 295                 300                 


Thr Asp Cys Val Arg Cys Leu Ala Val His Pro Asp Gly Val Arg Val 
305                 310                 315                 320 


Ala Ser Gly Gln Thr Ala Gly Val Asp Lys Asp Gly Lys Pro Leu Gln 
                325                 330                 335     


Pro Val Val His Ile Trp Asp Ser Glu Thr Leu Leu Lys Leu Gln Glu 
            340                 345                 350         


Ile Gly Leu Gly Ala Phe Glu Arg Gly Val Gly Ala Leu Ala Phe Ser 
        355                 360                 365             


Ala Ala Asp Gln Gly Ala Phe Leu Cys Val Val Asp Asp Ser Asn Glu 
    370                 375                 380                 


His Met Leu Ser Val Trp Asp Cys Ser Arg Gly Met Lys Leu Ala Glu 
385                 390                 395                 400 


Ile Lys Ser Thr Asn Asp Ser Val Leu Ala Val Gly Phe Asn Pro Arg 
                405                 410                 415     


Asp Ser Ser Cys Ile Val Thr Ser Gly Lys Ser His Val His Phe Trp 
            420                 425                 430         


Asn Trp Ser Gly Gly Val Gly Val Pro Gly Asn Gly Thr Leu Thr Arg 
        435                 440                 445             


Lys Gln Gly Val Phe Gly Lys Tyr Lys Lys Pro Lys Phe Ile Pro Cys 
    450                 455                 460                 


Phe Val Phe Leu Pro Asp Gly Asp Ile Leu Thr Gly Asp Ser Glu Gly 
465                 470                 475                 480 


Asn Ile Leu Thr Trp Gly Arg Ser Pro Ser Asp Ser Lys Thr Pro Gly 
                485                 490                 495     


Arg Gly Gly Ala Lys Glu Thr Tyr Gly Ile Val Ala Gln Ala His Ala 
            500                 505                 510         


His Glu Gly Ser Ile Phe Ala Leu Cys Leu Arg Arg Asp Gly Thr Val 
        515                 520                 525             


Leu Ser Gly Gly Gly Arg Asp Arg Arg Leu Val Gln Trp Gly Pro Gly 
    530                 535                 540                 


Leu Val Ala Leu Gln Glu Ala Glu Ile Pro Glu His Phe Gly Ala Val 
545                 550                 555                 560 


Arg Ala Ile Ala Glu Gly Leu Gly Ser Glu Leu Leu Val Gly Thr Thr 
                565                 570                 575     


Lys Asn Ala Leu Leu Arg Gly Asp Leu Ala Gln Gly Phe Ser Pro Val 
            580                 585                 590         


Ile Gln Gly His Thr Asp Glu Leu Trp Gly Leu Cys Thr His Pro Ser 
        595                 600                 605             


Gln Asn Arg Phe Leu Thr Cys Gly His Asp Arg Gln Leu Cys Leu Trp 
    610                 615                 620                 


Asp Gly Glu Ser His Ala Leu Ala Trp Ser Ile Asp Leu Lys Glu Thr 
625                 630                 635                 640 


Gly Leu Cys Ala Asp Phe His Pro Ser Gly Ala Val Val Ala Val Gly 
                645                 650                 655     


Leu Asn Thr Gly Arg Trp Leu Val Leu Asp Thr Glu Thr Arg Glu Ile 
            660                 665                 670         


Val Ser Asp Val Ile Asp Gly Asn Glu Gln Leu Ser Val Val Arg Tyr 
        675                 680                 685             


Ser Pro Asp Gly Leu Tyr Leu Ala Ile Gly Ser His Asp Asn Val Ile 
    690                 695                 700                 


Tyr Ile Tyr Ser Val Ser Ser Asp Gly Ala Lys Ser Ser Arg Phe Gly 
705                 710                 715                 720 


Arg Cys Met Gly His Ser Ser Phe Ile Thr His Leu Asp Trp Ser Lys 
                725                 730                 735     


Asp Gly Asn Phe Ile Met Ser Asn Ser Gly Asp Tyr Glu Ile Leu Tyr 
            740                 745                 750         


Trp Asp Val Ala Gly Gly Cys Lys Gln Leu Lys Asn Arg Tyr Glu Ser 
        755                 760                 765             


Arg Asp Arg Glu Trp Ala Thr Tyr Thr Cys Val Leu Gly Phe His Val 
    770                 775                 780                 


Tyr Gly Val Trp Pro Asp Gly Ser Asp Gly Thr Asp Ile Asn Ser Leu 
785                 790                 795                 800 


Cys Arg Ser His Asn Glu Arg Val Val Ala Val Ala Asp Asp Phe Cys 
                805                 810                 815     


Lys Val His Leu Phe Gln Tyr Pro Cys Ala Arg Ala Lys Ala Pro Ser 
            820                 825                 830         


Arg Met Tyr Gly Gly His Gly Ser His Val Thr Ser Val Arg Phe Thr 
        835                 840                 845             


His Asp Asp Ser His Leu Val Ser Leu Gly Gly Lys Asp Ala Ser Ile 
    850                 855                 860                 


Phe Gln Trp Arg Val Leu Gly Ala Gly Gly Ala Gly Pro Ala Pro Ala 
865                 870                 875                 880 


Thr Pro Ser Arg Thr Pro Ser Leu Ser Pro Ala Ser Ser Leu Asp Val 
                885                 890                 895     


<210>  1584
<211>  445
<212>  PRT
<213>  Homo sapiens

<400>  1584

Met Arg Glu Ile Val His Ile Gln Ala Gly Gln Cys Gly Asn Gln Ile 
1               5                   10                  15      


Gly Ala Lys Phe Trp Glu Val Ile Ser Asp Glu His Gly Ile Asp Pro 
            20                  25                  30          


Thr Gly Ser Tyr His Gly Asp Ser Asp Leu Gln Leu Glu Arg Ile Asn 
        35                  40                  45              


Val Tyr Tyr Asn Glu Ala Thr Gly Asn Lys Tyr Val Pro Arg Ala Ile 
    50                  55                  60                  


Leu Val Asp Leu Glu Pro Gly Thr Met Asp Ser Val Arg Ser Gly Pro 
65                  70                  75                  80  


Phe Gly Gln Ile Phe Arg Pro Asp Asn Phe Val Phe Gly Gln Ser Gly 
                85                  90                  95      


Ala Gly Asn Asn Trp Ala Lys Gly His Tyr Thr Glu Gly Ala Glu Leu 
            100                 105                 110         


Val Asp Ser Val Leu Asp Val Val Arg Lys Glu Ser Glu Ser Cys Asp 
        115                 120                 125             


Cys Leu Gln Gly Phe Gln Leu Thr His Ser Leu Gly Gly Gly Thr Gly 
    130                 135                 140                 


Ser Gly Met Gly Thr Leu Leu Ile Ser Lys Ile Arg Glu Glu Tyr Pro 
145                 150                 155                 160 


Asp Arg Ile Met Asn Thr Phe Ser Val Met Pro Ser Pro Lys Val Ser 
                165                 170                 175     


Asp Thr Val Val Glu Pro Tyr Asn Ala Thr Leu Ser Val His Gln Leu 
            180                 185                 190         


Val Glu Asn Thr Asp Glu Thr Tyr Cys Ile Asp Asn Glu Ala Leu Tyr 
        195                 200                 205             


Asp Ile Cys Phe Arg Thr Leu Lys Leu Thr Thr Pro Thr Tyr Gly Asp 
    210                 215                 220                 


Leu Asn His Leu Val Ser Ala Thr Met Ser Gly Val Thr Thr Cys Leu 
225                 230                 235                 240 


Arg Phe Pro Gly Gln Leu Asn Ala Asp Leu Arg Lys Leu Ala Val Asn 
                245                 250                 255     


Met Val Pro Phe Pro Arg Leu His Phe Phe Met Pro Gly Phe Ala Pro 
            260                 265                 270         


Leu Thr Ser Arg Gly Ser Gln Gln Tyr Arg Ala Leu Thr Val Pro Glu 
        275                 280                 285             


Leu Thr Gln Gln Met Phe Asp Ser Lys Asn Met Met Ala Ala Cys Asp 
    290                 295                 300                 


Pro Arg His Gly Arg Tyr Leu Thr Val Ala Ala Ile Phe Arg Gly Arg 
305                 310                 315                 320 


Met Ser Met Lys Glu Val Asp Glu Gln Met Leu Asn Val Gln Asn Lys 
                325                 330                 335     


Asn Ser Ser Tyr Phe Val Glu Trp Ile Pro Asn Asn Val Lys Thr Ala 
            340                 345                 350         


Val Cys Asp Ile Pro Pro Arg Gly Leu Lys Met Ser Ala Thr Phe Ile 
        355                 360                 365             


Gly Asn Ser Thr Ala Ile Gln Glu Leu Phe Lys Arg Ile Ser Glu Gln 
    370                 375                 380                 


Phe Thr Ala Met Phe Arg Arg Lys Ala Phe Leu His Trp Tyr Thr Gly 
385                 390                 395                 400 


Glu Gly Met Asp Glu Met Glu Phe Thr Glu Ala Glu Ser Asn Met Asn 
                405                 410                 415     


Asp Leu Val Ser Glu Tyr Gln Gln Tyr Gln Asp Ala Thr Ala Asp Glu 
            420                 425                 430         


Gln Gly Glu Phe Glu Glu Glu Glu Gly Glu Asp Glu Ala 
        435                 440                 445 


<210>  1585
<211>  641
<212>  PRT
<213>  Homo sapiens

<400>  1585

Met Ala Lys Ala Ala Ala Ile Gly Ile Asp Leu Gly Thr Thr Tyr Ser 
1               5                   10                  15      


Cys Val Gly Val Phe Gln His Gly Lys Val Glu Ile Ile Ala Asn Asp 
            20                  25                  30          


Gln Gly Asn Arg Thr Thr Pro Ser Tyr Val Ala Phe Thr Asp Thr Glu 
        35                  40                  45              


Arg Leu Ile Gly Asp Ala Ala Lys Asn Gln Val Ala Leu Asn Pro Gln 
    50                  55                  60                  


Asn Thr Val Phe Asp Ala Lys Arg Leu Ile Gly Arg Lys Phe Gly Asp 
65                  70                  75                  80  


Pro Val Val Gln Ser Asp Met Lys His Trp Pro Phe Gln Val Ile Asn 
                85                  90                  95      


Asp Gly Asp Lys Pro Lys Val Gln Val Ser Tyr Lys Gly Glu Thr Lys 
            100                 105                 110         


Ala Phe Tyr Pro Glu Glu Ile Ser Ser Met Val Leu Thr Lys Met Lys 
        115                 120                 125             


Glu Ile Ala Glu Ala Tyr Leu Gly Tyr Pro Val Thr Asn Ala Val Ile 
    130                 135                 140                 


Thr Val Pro Ala Tyr Phe Asn Asp Ser Gln Arg Gln Ala Thr Lys Asp 
145                 150                 155                 160 


Ala Gly Val Ile Ala Gly Leu Asn Val Leu Arg Ile Ile Asn Glu Pro 
                165                 170                 175     


Thr Ala Ala Ala Ile Ala Tyr Gly Leu Asp Arg Thr Gly Lys Gly Glu 
            180                 185                 190         


Arg Asn Val Leu Ile Phe Asp Leu Gly Gly Gly Thr Phe Asp Val Ser 
        195                 200                 205             


Ile Leu Thr Ile Asp Asp Gly Ile Phe Glu Val Lys Ala Thr Ala Gly 
    210                 215                 220                 


Asp Thr His Leu Gly Gly Glu Asp Phe Asp Asn Arg Leu Val Asn His 
225                 230                 235                 240 


Phe Val Glu Glu Phe Lys Arg Lys His Lys Lys Asp Ile Ser Gln Asn 
                245                 250                 255     


Lys Arg Ala Val Arg Arg Leu Arg Thr Ala Cys Glu Arg Ala Lys Arg 
            260                 265                 270         


Thr Leu Ser Ser Ser Thr Gln Ala Ser Leu Glu Ile Asp Ser Leu Phe 
        275                 280                 285             


Glu Gly Ile Asp Phe Tyr Thr Ser Ile Thr Arg Ala Arg Phe Glu Glu 
    290                 295                 300                 


Leu Cys Ser Asp Leu Phe Arg Ser Thr Leu Glu Pro Val Glu Lys Ala 
305                 310                 315                 320 


Leu Arg Asp Ala Lys Leu Asp Lys Ala Gln Ile His Asp Leu Val Leu 
                325                 330                 335     


Val Gly Gly Ser Thr Arg Ile Pro Lys Val Gln Lys Leu Leu Gln Asp 
            340                 345                 350         


Phe Phe Asn Gly Arg Asp Leu Asn Lys Ser Ile Asn Pro Asp Glu Ala 
        355                 360                 365             


Val Ala Tyr Gly Ala Ala Val Gln Ala Ala Ile Leu Met Gly Asp Lys 
    370                 375                 380                 


Ser Glu Asn Val Gln Asp Leu Leu Leu Leu Asp Val Ala Pro Leu Ser 
385                 390                 395                 400 


Leu Gly Leu Glu Thr Ala Gly Gly Val Met Thr Ala Leu Ile Lys Arg 
                405                 410                 415     


Asn Ser Thr Ile Pro Thr Lys Gln Thr Gln Ile Phe Thr Thr Tyr Ser 
            420                 425                 430         


Asp Asn Gln Pro Gly Val Leu Ile Gln Val Tyr Glu Gly Glu Arg Ala 
        435                 440                 445             


Met Thr Lys Asp Asn Asn Leu Leu Gly Arg Phe Glu Leu Ser Gly Ile 
    450                 455                 460                 


Pro Pro Ala Pro Arg Gly Val Pro Gln Ile Glu Val Thr Phe Asp Ile 
465                 470                 475                 480 


Asp Ala Asn Gly Ile Leu Asn Val Thr Ala Thr Asp Lys Ser Thr Gly 
                485                 490                 495     


Lys Ala Asn Lys Ile Thr Ile Thr Asn Asp Lys Gly Arg Leu Ser Lys 
            500                 505                 510         


Glu Glu Ile Glu Arg Met Val Gln Glu Ala Glu Lys Tyr Lys Ala Glu 
        515                 520                 525             


Asp Glu Val Gln Arg Glu Arg Val Ser Ala Lys Asn Ala Leu Glu Ser 
    530                 535                 540                 


Tyr Ala Phe Asn Met Lys Ser Ala Val Glu Asp Glu Gly Leu Lys Gly 
545                 550                 555                 560 


Lys Ile Ser Glu Ala Asp Lys Lys Lys Val Leu Asp Lys Cys Gln Glu 
                565                 570                 575     


Val Ile Ser Trp Leu Asp Ala Asn Thr Leu Ala Glu Lys Asp Glu Phe 
            580                 585                 590         


Glu His Lys Arg Lys Glu Leu Glu Gln Val Cys Asn Pro Ile Ile Ser 
        595                 600                 605             


Gly Leu Tyr Gln Gly Ala Gly Gly Pro Gly Pro Gly Gly Phe Gly Ala 
    610                 615                 620                 


Gln Gly Pro Lys Gly Gly Ser Gly Ser Gly Pro Thr Ile Glu Glu Val 
625                 630                 635                 640 


Asp 
    


<210>  1586
<211>  436
<212>  PRT
<213>  Homo sapiens

<400>  1586

Met Arg Leu Ala Arg Leu Leu Arg Gly Ala Ala Leu Ala Gly Pro Gly 
1               5                   10                  15      


Pro Gly Leu Arg Ala Ala Gly Phe Ser Arg Ser Phe Ser Ser Asp Ser 
            20                  25                  30          


Gly Ser Ser Pro Ala Ser Glu Arg Gly Val Pro Gly Gln Val Asp Phe 
        35                  40                  45              


Tyr Ala Arg Phe Ser Pro Ser Pro Leu Ser Met Lys Gln Phe Leu Asp 
    50                  55                  60                  


Phe Gly Ser Val Asn Ala Cys Glu Lys Thr Ser Phe Met Phe Leu Arg 
65                  70                  75                  80  


Gln Glu Leu Pro Val Arg Leu Ala Asn Ile Met Lys Glu Ile Ser Leu 
                85                  90                  95      


Leu Pro Asp Asn Leu Leu Arg Thr Pro Ser Val Gln Leu Val Gln Ser 
            100                 105                 110         


Trp Tyr Ile Gln Ser Leu Gln Glu Leu Leu Asp Phe Lys Asp Lys Ser 
        115                 120                 125             


Ala Glu Asp Ala Lys Ala Ile Tyr Asp Phe Thr Asp Thr Val Ile Arg 
    130                 135                 140                 


Ile Arg Asn Arg His Asn Asp Val Ile Pro Thr Met Ala Gln Gly Val 
145                 150                 155                 160 


Ile Glu Tyr Lys Glu Ser Phe Gly Val Asp Pro Val Thr Ser Gln Asn 
                165                 170                 175     


Val Gln Tyr Phe Leu Asp Arg Phe Tyr Met Ser Arg Ile Ser Ile Arg 
            180                 185                 190         


Met Leu Leu Asn Gln His Ser Leu Leu Phe Gly Gly Lys Gly Lys Gly 
        195                 200                 205             


Ser Pro Ser His Arg Lys His Ile Gly Ser Ile Asn Pro Asn Cys Asn 
    210                 215                 220                 


Val Leu Glu Val Ile Lys Asp Gly Tyr Glu Asn Ala Arg Arg Leu Cys 
225                 230                 235                 240 


Asp Leu Tyr Tyr Ile Asn Ser Pro Glu Leu Glu Leu Glu Glu Leu Asn 
                245                 250                 255     


Ala Lys Ser Pro Gly Gln Pro Ile Gln Val Val Tyr Val Pro Ser His 
            260                 265                 270         


Leu Tyr His Met Val Phe Glu Leu Phe Lys Asn Ala Met Arg Ala Thr 
        275                 280                 285             


Met Glu His His Ala Asn Arg Gly Val Tyr Pro Pro Ile Gln Val His 
    290                 295                 300                 


Val Thr Leu Gly Asn Glu Asp Leu Thr Val Lys Met Ser Asp Arg Gly 
305                 310                 315                 320 


Gly Gly Val Pro Leu Arg Lys Ile Asp Arg Leu Phe Asn Tyr Met Tyr 
                325                 330                 335     


Ser Thr Ala Pro Arg Pro Arg Val Glu Thr Ser Arg Ala Val Pro Leu 
            340                 345                 350         


Ala Gly Phe Gly Tyr Gly Leu Pro Ile Ser Arg Leu Tyr Ala Gln Tyr 
        355                 360                 365             


Phe Gln Gly Asp Leu Lys Leu Tyr Ser Leu Glu Gly Tyr Gly Thr Asp 
    370                 375                 380                 


Ala Val Ile Tyr Ile Lys Ala Leu Ser Thr Asp Ser Ile Glu Arg Leu 
385                 390                 395                 400 


Pro Val Tyr Asn Lys Ala Ala Trp Lys His Tyr Asn Thr Asn His Glu 
                405                 410                 415     


Ala Asp Asp Trp Cys Val Pro Ser Arg Glu Pro Lys Asp Met Thr Thr 
            420                 425                 430         


Phe Arg Ser Ala 
        435     


<210>  1587
<211>  829
<212>  PRT
<213>  Homo sapiens

<400>  1587

Met Gly Leu Pro Arg Gly Pro Leu Ala Ser Leu Leu Leu Leu Gln Val 
1               5                   10                  15      


Cys Trp Leu Gln Cys Ala Ala Ser Glu Pro Cys Arg Ala Val Phe Arg 
            20                  25                  30          


Glu Ala Glu Val Thr Leu Glu Ala Gly Gly Ala Glu Gln Glu Pro Gly 
        35                  40                  45              


Gln Ala Leu Gly Lys Val Phe Met Gly Cys Pro Gly Gln Glu Pro Ala 
    50                  55                  60                  


Leu Phe Ser Thr Asp Asn Asp Asp Phe Thr Val Arg Asn Gly Glu Thr 
65                  70                  75                  80  


Val Gln Glu Arg Arg Ser Leu Lys Glu Arg Asn Pro Leu Lys Ile Phe 
                85                  90                  95      


Pro Ser Lys Arg Ile Leu Arg Arg His Lys Arg Asp Trp Val Val Ala 
            100                 105                 110         


Pro Ile Ser Val Pro Glu Asn Gly Lys Gly Pro Phe Pro Gln Arg Leu 
        115                 120                 125             


Asn Gln Leu Lys Ser Asn Lys Asp Arg Asp Thr Lys Ile Phe Tyr Ser 
    130                 135                 140                 


Ile Thr Gly Pro Gly Ala Asp Ser Pro Pro Glu Gly Val Phe Ala Val 
145                 150                 155                 160 


Glu Lys Glu Thr Gly Trp Leu Leu Leu Asn Lys Pro Leu Asp Arg Glu 
                165                 170                 175     


Glu Ile Ala Lys Tyr Glu Leu Phe Gly His Ala Val Ser Glu Asn Gly 
            180                 185                 190         


Ala Ser Val Glu Asp Pro Met Asn Ile Ser Ile Ile Val Thr Asp Gln 
        195                 200                 205             


Asn Asp His Lys Pro Lys Phe Thr Gln Asp Thr Phe Arg Gly Ser Val 
    210                 215                 220                 


Leu Glu Gly Val Leu Pro Gly Thr Ser Val Met Gln Val Thr Ala Thr 
225                 230                 235                 240 


Asp Glu Asp Asp Ala Ile Tyr Thr Tyr Asn Gly Val Val Ala Tyr Ser 
                245                 250                 255     


Ile His Ser Gln Glu Pro Lys Asp Pro His Asp Leu Met Phe Thr Ile 
            260                 265                 270         


His Arg Ser Thr Gly Thr Ile Ser Val Ile Ser Ser Gly Leu Asp Arg 
        275                 280                 285             


Glu Lys Val Pro Glu Tyr Thr Leu Thr Ile Gln Ala Thr Asp Met Asp 
    290                 295                 300                 


Gly Asp Gly Ser Thr Thr Thr Ala Val Ala Val Val Glu Ile Leu Asp 
305                 310                 315                 320 


Ala Asn Asp Asn Ala Pro Met Phe Asp Pro Gln Lys Tyr Glu Ala His 
                325                 330                 335     


Val Pro Glu Asn Ala Val Gly His Glu Val Gln Arg Leu Thr Val Thr 
            340                 345                 350         


Asp Leu Asp Ala Pro Asn Ser Pro Ala Trp Arg Ala Thr Tyr Leu Ile 
        355                 360                 365             


Met Gly Gly Asp Asp Gly Asp His Phe Thr Ile Thr Thr His Pro Glu 
    370                 375                 380                 


Ser Asn Gln Gly Ile Leu Thr Thr Arg Lys Gly Leu Asp Phe Glu Ala 
385                 390                 395                 400 


Lys Asn Gln His Thr Leu Tyr Val Glu Val Thr Asn Glu Ala Pro Phe 
                405                 410                 415     


Val Leu Lys Leu Pro Thr Ser Thr Ala Thr Ile Val Val His Val Glu 
            420                 425                 430         


Asp Val Asn Glu Ala Pro Val Phe Val Pro Pro Ser Lys Val Val Glu 
        435                 440                 445             


Val Gln Glu Gly Ile Pro Thr Gly Glu Pro Val Cys Val Tyr Thr Ala 
    450                 455                 460                 


Glu Asp Pro Asp Lys Glu Asn Gln Lys Ile Ser Tyr Arg Ile Leu Arg 
465                 470                 475                 480 


Asp Pro Ala Gly Trp Leu Ala Met Asp Pro Asp Ser Gly Gln Val Thr 
                485                 490                 495     


Ala Val Gly Thr Leu Asp Arg Glu Asp Glu Gln Phe Val Arg Asn Asn 
            500                 505                 510         


Ile Tyr Glu Val Met Val Leu Ala Met Asp Asn Gly Ser Pro Pro Thr 
        515                 520                 525             


Thr Gly Thr Gly Thr Leu Leu Leu Thr Leu Ile Asp Val Asn Asp His 
    530                 535                 540                 


Gly Pro Val Pro Glu Pro Arg Gln Ile Thr Ile Cys Asn Gln Ser Pro 
545                 550                 555                 560 


Val Arg Gln Val Leu Asn Ile Thr Asp Lys Asp Leu Ser Pro His Thr 
                565                 570                 575     


Ser Pro Phe Gln Ala Gln Leu Thr Asp Asp Ser Asp Ile Tyr Trp Thr 
            580                 585                 590         


Ala Glu Val Asn Glu Glu Gly Asp Thr Val Val Leu Ser Leu Lys Lys 
        595                 600                 605             


Phe Leu Lys Gln Asp Thr Tyr Asp Val His Leu Ser Leu Ser Asp His 
    610                 615                 620                 


Gly Asn Lys Glu Gln Leu Thr Val Ile Arg Ala Thr Val Cys Asp Cys 
625                 630                 635                 640 


His Gly His Val Glu Thr Cys Pro Gly Pro Trp Lys Gly Gly Phe Ile 
                645                 650                 655     


Leu Pro Val Leu Gly Ala Val Leu Ala Leu Leu Phe Leu Leu Leu Val 
            660                 665                 670         


Leu Leu Leu Leu Val Arg Lys Lys Arg Lys Ile Lys Glu Pro Leu Leu 
        675                 680                 685             


Leu Pro Glu Asp Asp Thr Arg Asp Asn Val Phe Tyr Tyr Gly Glu Glu 
    690                 695                 700                 


Gly Gly Gly Glu Glu Asp Gln Asp Tyr Asp Ile Thr Gln Leu His Arg 
705                 710                 715                 720 


Gly Leu Glu Ala Arg Pro Glu Val Val Leu Arg Asn Asp Val Ala Pro 
                725                 730                 735     


Thr Ile Ile Pro Thr Pro Met Tyr Arg Pro Arg Pro Ala Asn Pro Asp 
            740                 745                 750         


Glu Ile Gly Asn Phe Ile Ile Glu Asn Leu Lys Ala Ala Asn Thr Asp 
        755                 760                 765             


Pro Thr Ala Pro Pro Tyr Asp Thr Leu Leu Val Phe Asp Tyr Glu Gly 
    770                 775                 780                 


Ser Gly Ser Asp Ala Ala Ser Leu Ser Ser Leu Thr Ser Ser Ala Ser 
785                 790                 795                 800 


Asp Gln Asp Gln Asp Tyr Asp Tyr Leu Asn Glu Trp Gly Ser Arg Phe 
                805                 810                 815     


Lys Lys Leu Ala Asp Met Tyr Gly Gly Gly Glu Asp Asp 
            820                 825                 


