                               SEQUENCE LISTING

<110> NOVARTIS AG
 
<120> METHODS OF TREATING COLORECTAL CANCERS HARBORING UPSTREAM WNT 
      PATHWAY MUTATIONS

<130> PAT056178-WO-PCT

<140> PCT/IB2015/052245
<141> 2015-03-26

<150> 62/119,939
<151> 2015-02-24

<150> 61/971,162
<151> 2014-03-27

<160> 16    

<170> PatentIn version 3.5

<210> 1
<211> 22
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      primer"

<400> 1
ttggatcggc atctagtctt tc                                                22


<210> 2
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      probe"

<400> 2
tctgtaaagg aggttcgtgg cgg                                               23


<210> 3
<211> 18
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      primer"

<400> 3
tcagttcagc gcgatcag                                                     18


<210> 4
<211> 26
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      primer"

<400> 4
ttctctctgt aaaggagcta gttatg                                            26


<210> 5
<211> 27
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      probe"

<400> 5
tcccatttgc aagggttgtt tgtcttg                                           27


<210> 6
<211> 19
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      primer"

<400> 6
acaatgggtg tagccgatg                                                    19


<210> 7
<211> 18
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      primer"

<400> 7
gcttttgtgg cgctcttg                                                     18


<210> 8
<211> 24
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      probe"

<400> 8
agttctccgc agtgcatcct aacg                                              24


<210> 9
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      primer"

<400> 9
gggcttacat gacaaacatc c                                                 21


<210> 10
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      primer"

<400> 10
ttacaagacc tggtgaaggt g                                                 21


<210> 11
<211> 43
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      probe"

<400> 11
ctaatcacca gaacaaaatg tgcagtgcat cctaacgtta gtc                         43


<210> 12
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      primer"

<400> 12
agtctgggct tacatgacaa a                                                 21


<210> 13
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      primer"

<400> 13
aaactcggca tggatacgac                                                   20


<210> 14
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      primer"

<400> 14
gcttcatgcc aattctttcc                                                   20


<210> 15
<211> 48
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"


<220>
<221> CDS
<222> (1)..(48)

<400> 15
cgg ccc aag gcc agt tct ccg cag tgc atc cta acg tta gtc aag gct         48
Arg Pro Lys Ala Ser Ser Pro Gln Cys Ile Leu Thr Leu Val Lys Ala           
1               5                   10                  15                


<210> 16
<211> 16
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"

<400> 16
Arg Pro Lys Ala Ser Ser Pro Gln Cys Ile Leu Thr Leu Val Lys Ala 
1               5                   10                  15      


