                         SEQUENCE LISTING

<110>  Universit Paul SABATIER -Toulouse III
       Centre National de la Recherche Scientifique
       Centre Hospitalier Universitaire de Toulouse
       Institut National de la Sant et de la Recherche Mdicale
       MULLER, Catherine
       LAURENT, Victor
       GUERARD, Adrien
       VALET, Philippe
       MALAVAUD, Bernard
 
<120>  INHIBITION DE LA CHIMIOKINE CCL7 OU DE SON RECEPTEUR CCR3 POUR LE
        TRAITEMENT ET LE DIAGNOSTIC DU CANCER DE LA PROSTATE

<130>  F2541-1-FR_XRN/clg

<150>  FR1455491
<151>  2014-06-16

<160>  25    

<170>  PatentIn version 3.5

<210>  1
<211>  67
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  shRNA

<400>  1
cgcgtcccca gaccacaccc tatgaatatt caagagatat tcatagggtg tggtcttttt       60

tggaaat                                                                 67


<210>  2
<211>  67
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  shRNA

<400>  2
cgcgtccccg accacaccct atgaatattt caagagaata ttcatagggt gtggtctttt       60

tggaaat                                                                 67


<210>  3
<211>  68
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  shRNA

<400>  3
cgccgtcccc ggtgagaggt tccggaaact tcaagagagt ttccggaacc tctcaccttt       60

ttggaaat                                                                68


<210>  4
<211>  23
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Primer

<400>  4
aaacctccaa ttctcatgtg gaa                                               23


<210>  5
<211>  21
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Primer

<400>  5
cagaagtgct gcagaggctt t                                                 21


<210>  6
<211>  23
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Primer

<400>  6
aaacctccaa ttctcatgtg gaa                                               23


<210>  7
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Primer

<400>  7
cttcccaggg acaccgacta                                                   20


<210>  8
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Primer

<400>  8
tgcaccacca actgcttagc                                                   20


<210>  9
<211>  21
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Primer

<400>  9
ggcatggact gtggtcatga g                                                 21


<210>  10
<211>  21
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Primer

<400>  10
tgacactggc aaaacaatgc a                                                 21


<210>  11
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Primer

<400>  11
gcttgcgacc ttgaccatct                                                   20


<210>  12
<211>  21
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Primer

<400>  12
tggccatctg cctagtaaag c                                                 21


<210>  13
<211>  21
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Primer

<400>  13
ggacgcagca actgacattt c                                                 21


<210>  14
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  siRNA


<220>
<221>  modified_base
<222>  (9)..(9)
<223>  Replace = 2,6-Diaminopurine

<220>
<221>  modified_base
<222>  (15)..(15)
<223>  Replace = 2,6-Diaminopurine

<400>  14
gggtctgcag cgggatggt                                                    19


<210>  15
<211>  21
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  siRNA


<220>
<221>  modified_base
<222>  (4)..(4)
<223>  Replace = 2,6-Diaminopurine

<220>
<221>  modified_base
<222>  (7)..(7)
<223>  Replace = 2,6-Diaminopurine

<220>
<221>  modified_base
<222>  (13)..(13)
<223>  Replace = 2,6-Diaminopurine

<400>  15
gttactactt ccacctgcct g                                                 21


<210>  16
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Antisens oligonucleotide


<220>
<221>  misc_feature
<222>  (1)..(19)
<223>  All linkages are phophorothioate

<400>  16
cacctctgtc accagcatg                                                    19


<210>  17
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Antisens oligonucleotide


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (2)..(2)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (5)..(6)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  misc_feature
<222>  (9)..(10)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (11)..(11)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (13)..(14)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (14)..(14)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  modified_base
<222>  (17)..(17)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (17)..(18)
<223>  Linkage to next nucleotide is phophorothioate

<400>  17
cacctctgtc nccagcatg                                                    19


<210>  18
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Antisens oligonucleotide


<220>
<221>  misc_feature
<222>  (1)..(3)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (2)..(2)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (6)..(7)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (11)..(11)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (12)..(13)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (14)..(14)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (14)..(14)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (16)..(18)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (17)..(17)
<223>  Replace = 2-amino-2'-deoxyadenosine

<400>  18
cacctctgtc nccngcatg                                                    19


<210>  19
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Antisens oligonucleotide


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (2)..(2)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (6)..(7)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (11)..(11)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (11)..(12)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (14)..(14)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (14)..(14)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (16)..(18)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (17)..(17)
<223>  Replace = 2-amino-2'-deoxyadenosine

<400>  19
cacctctgtc accngcatg                                                    19


<210>  20
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Antisens oligonucleotide


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (2)..(2)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (6)..(7)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (11)..(11)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (11)..(12)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (14)..(14)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (14)..(14)
<223>  n is a, c, g, or t

<220>
<221>  modified_base
<222>  (17)..(17)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (17)..(18)
<223>  Linkage to next nucleotide is phophorothioate

<400>  20
cacctctgtc accngcatg                                                    19


<210>  21
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Antisens oligonucleotide


<220>
<221>  misc_feature
<222>  (1)..(3)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (2)..(2)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (5)..(6)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  misc_feature
<222>  (8)..(10)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (11)..(11)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (12)..(15)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (14)..(14)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  modified_base
<222>  (17)..(17)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (17)..(18)
<223>  Linkage to next nucleotide is phophorothioate

<400>  21
cacctctgtc nccagcatg                                                    19


<210>  22
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Antisens oligonucleotide


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (2)..(2)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (5)..(8)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (11)..(11)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (11)..(13)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (14)..(14)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (14)..(14)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (16)..(18)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (17)..(17)
<223>  Replace = 2-amino-2'-deoxyadenosine

<400>  22
cacctctgtc accngcatg                                                    19


<210>  23
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Antisens oligonucleotide


<220>
<221>  misc_feature
<222>  (1)..(6)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (2)..(2)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  modified_base
<222>  (11)..(11)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (13)..(18)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (14)..(14)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  modified_base
<222>  (17)..(17)
<223>  Replace = 2-amino-2'-deoxyadenosine

<400>  23
cacctctgtc nccagcatg                                                    19


<210>  24
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Antisens oligonucleotide


<220>
<221>  misc_feature
<222>  (1)..(7)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (2)..(2)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  modified_base
<222>  (11)..(11)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (12)..(18)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (14)..(14)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  modified_base
<222>  (17)..(17)
<223>  Replace = 2-amino-2'-deoxyadenosine

<400>  24
cacctctgtc nccagcatg                                                    19


<210>  25
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Antisens oligonucleotide


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (2)..(2)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (6)..(12)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (11)..(11)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  modified_base
<222>  (14)..(14)
<223>  Replace = 2-amino-2'-deoxyadenosine

<220>
<221>  misc_feature
<222>  (14)..(14)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (16)..(18)
<223>  Linkage to next nucleotide is phophorothioate

<220>
<221>  modified_base
<222>  (17)..(17)
<223>  Replace = 2-amino-2'-deoxyadenosine

<400>  25
cacctctgtc accngcatg                                                    19


