                               SEQUENCE LISTING

<110> SANGAMO BIOSCIENCES, INC.
 
<120> METHODS AND COMPOSITIONS FOR NUCLEASE-MEDIATED GENOME 
      ENGINEERING AND CORRECTION IN HEMATOPOIETIC STEM CELLS

<130> 8328-0127.40

<140> PCT/US2015/050411
<141> 2015-09-16

<150> 62/051,159
<151> 2014-09-16

<160> 71    

<170> PatentIn version 3.5

<210> 1
<211> 25
<212> DNA
<213> Homo sapiens

<400> 1
ctgacctctt ctcttcctcc cacag                                             25


<210> 2
<211> 13
<212> DNA
<213> Homo sapiens

<400> 2
tttctctcca cag                                                          13


<210> 3
<211> 64
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 3
tcaaacagac accatggtgc atctgactcc tgaggagaag tctgccgtta ctgccctgtg       60

gggc                                                                    64


<210> 4
<211> 12
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 4
actcctgagg ag                                                           12


<210> 5
<211> 15
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 5
actcctaggg aggag                                                        15


<210> 6
<211> 41
<212> DNA
<213> Homo sapiens

<400> 6
caccatggtg catctgactc ctgaggagaa gtctgccgtt a                           41


<210> 7
<211> 41
<212> DNA
<213> Homo sapiens

<400> 7
caccatggtg catctgactc ctgaggagaa gactgctgtc a                           41


<210> 8
<211> 41
<212> DNA
<213> Homo sapiens

<400> 8
catcatggtg cattttactg ctgaggagaa ggctgccgtc a                           41


<210> 9
<211> 41
<212> DNA
<213> Homo sapiens

<400> 9
cactgtagtg catttcactg ctgacaagaa ggctgctgcc a                           41


<210> 10
<211> 41
<212> DNA
<213> Homo sapiens

<400> 10
cgccatgggt catttcacag aggaggacaa ggctactatc a                           41


<210> 11
<211> 41
<212> DNA
<213> Homo sapiens

<400> 11
cgccatgggt catttcacag aggaggacaa ggctactatc a                           41


<210> 12
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 12
Leu Arg His His Leu Thr Arg 
1               5           


<210> 13
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 13
Leu Arg His Asn Leu Arg Ala 
1               5           


<210> 14
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 14
Asp Gln Ser Asn Leu Arg Ala 
1               5           


<210> 15
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 15
Arg Asn Ala Ser Arg Thr Arg 
1               5           


<210> 16
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 16
Arg Ser Asp Asn Leu Ser Glu 
1               5           


<210> 17
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 17
Arg Ser Gln His Arg Lys Thr 
1               5           


<210> 18
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 18
Thr Ser Gly Ser Leu Ser Arg 
1               5           


<210> 19
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 19
Asp Arg Ser Asp Leu Ser Arg 
1               5           


<210> 20
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 20
Asp Arg Ser Ala Leu Ala Arg 
1               5           


<210> 21
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 21
Gln Ser Ser Asn Leu Ala Arg 
1               5           


<210> 22
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 22
Gln Ser Gly His Leu Ser Arg 
1               5           


<210> 23
<211> 28
<212> DNA
<213> Homo sapiens

<400> 23
ggagtcaggt gcaccatggt gtctgttt                                          28


<210> 24
<211> 28
<212> DNA
<213> Homo sapiens

<400> 24
gtggagaagt ctgccgttac tgccctgt                                          28


<210> 25
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 25
gacaggtacg gctgtcatca                                                   20


<210> 26
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 26
cagcctaagg gtgggaaaat                                                   20


<210> 27
<211> 24
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 27
atgcttagaa ccgaggtaga gttt                                              24


<210> 28
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 28
cctgagactt ccacactgat g                                                 21


<210> 29
<211> 19
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 29
gaagtctgcc gttactgcg                                                    19


<210> 30
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 30
cccagtttct attggtctcc                                                   20


<210> 31
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 31
ctcggtgcct ttagtgatgg                                                   20


<210> 32
<211> 19
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 32
gactcaccct gaagttctc                                                    19


<210> 33
<211> 44
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer


<220>
<221> modified_base
<222> (21)..(24)
<223> a, c, t, g, unknown or other

<400> 33
acacgacgct cttccgatct nnnngggctg ggcataaaag tcag                        44


<210> 34
<211> 41
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 34
gacgtgtgct cttccgatct tccacatgcc cagtttctat t                           41


<210> 35
<211> 45
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer


<220>
<221> modified_base
<222> (21)..(24)
<223> a, c, t, g, unknown or other

<400> 35
acacgacgct cttccgatct nnnntaaaag gcagggcaga gtcga                       45


<210> 36
<211> 41
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 36
gacgtgtgct cttccgatct acatgcccag tttccatttg c                           41


<210> 37
<211> 45
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer


<220>
<221> modified_base
<222> (21)..(24)
<223> a, c, t, g, unknown or other

<400> 37
acacgacgct cttccgatct nnnnctgctt ccgacacagc tgcaa                       45


<210> 38
<211> 41
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 38
gacgtgtgct cttccgatct tcacccttca ttcccatgca t                           41


<210> 39
<211> 45
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer


<220>
<221> modified_base
<222> (21)..(24)
<223> a, c, t, g, unknown or other

<400> 39
acacgacgct cttccgatct nnnnggaacg tctgaggtta tcaat                       45


<210> 40
<211> 38
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 40
gacgtgtgct cttccgatct tccttccctc ccttgtcc                               38


<210> 41
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 41
ggttcatttt tcattctcac a                                                 21


<210> 42
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 42
gtaatctgag ggtaggaaaa c                                                 21


<210> 43
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 43
gagactgtgg gatagtcata                                                   20


<210> 44
<211> 22
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 44
cattatcaca aacttagtgt cc                                                22


<210> 45
<211> 22
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 45
agtctatgaa atgacaccat at                                                22


<210> 46
<211> 24
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 46
gcaaaggcta taaaaaaaat tagc                                              24


<210> 47
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 47
gagatcatcc aggtgctttg                                                   20


<210> 48
<211> 27
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 48
ggcaaaggct ataaaaaaaa ttaagca                                           27


<210> 49
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 49
gagatcatcc aggtgcttta                                                   20


<210> 50
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 50
acatttgctt ctgacacaac                                                   20


<210> 51
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 51
gaaattggac agcaagaaag c                                                 21


<210> 52
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 52
cacccttgac caatagattc                                                   20


<210> 53
<211> 18
<212> DNA
<213> Homo sapiens

<400> 53
gaggagaagt ctgccgtt                                                     18


<210> 54
<211> 18
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 54
gaagaaaaaa gcgctgtg                                                     18


<210> 55
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 55
Leu Lys Gln Asn Leu Asp Ala 
1               5           


<210> 56
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 56
Arg Asn Cys Ala Arg Leu Arg 
1               5           


<210> 57
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 57
Arg Asn Gln Thr Arg Leu Asn 
1               5           


<210> 58
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 58
His His His Ser Leu Lys Arg 
1               5           


<210> 59
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 59
Thr Asn Ser Glu Leu Asp Arg 
1               5           


<210> 60
<211> 18
<212> DNA
<213> Homo sapiens

<400> 60
gaggagaagt ctgccgtt                                                     18


<210> 61
<211> 18
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 61
gaggaaaagt ctgccgtt                                                     18


<210> 62
<211> 18
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 62
gaggagaaat ctgccgtt                                                     18


<210> 63
<211> 18
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 63
gaggagaagt ctgctgtt                                                     18


<210> 64
<211> 18
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 64
gaggaaaaat ctgccgtt                                                     18


<210> 65
<211> 18
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 65
gaggaaaagt ctgctgtt                                                     18


<210> 66
<211> 18
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 66
gaggagaaat ctgctgtt                                                     18


<210> 67
<211> 18
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 67
gaggaaaaat ctgctgtt                                                     18


<210> 68
<211> 18
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 68
gaagaaaaat ctgccgtt                                                     18


<210> 69
<211> 18
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 69
gtggaaaaat ctgccgtt                                                     18


<210> 70
<211> 18
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 70
gtagaaaaat ctgccgtt                                                     18


<210> 71
<211> 9
<212> PRT
<213> Unknown

<220>
<223> Description of Unknown: 'LAGLIDADG' family
      meganuclease motif peptide

<400> 71
Leu Ala Gly Leu Ile Asp Ala Asp Gly 
1               5                   


