                         SEQUENCE LISTING

<110>  Trustees of Tufts College
       Board of Regents of the University of Texas System
       Kritzer, Joshua
       Levine, Beth
       Peraro, Leila
 
<120>  CYCLIC PEPTIDE EPITOPES AND SMALL-MOLECULE MIMICS FOR INDUCING 
       AUTOPHAGY

<130>  167774-010403

<140>  PCT/US2017/022974
<141>  2017-03-17

<150>  62/424,934
<151>  2016-11-21

<150>  62/310,448
<151>  2016-03-18

<160>  75    

<170>  PatentIn version 3.5

<210>  1
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide


<220>
<221>  misc_feature
<222>  (1)
<223>  Xaa can Cys, Asp, Gly, Thr, Val, Trp

<220>
<221>  misc_feature
<222>  (2)
<223>  Xaa can be Cys, D-Cys, Phe, His, Leu, Asn,
       Trp, Tyr

<220>
<221>  misc_feature
<222>  (3)
<223>  Xaa can be Ala, Asp, Asn, Trp

<220>
<221>  misc_feature
<222>  (4)
<223>  Xaa can be Ala, Ile, Ser, Thr

<220>
<221>  misc_feature
<222>  (5)
<223>  Xaa can be Ala, Cys, D-Cys, Phe, His, Thr

<220>
<221>  misc_feature
<222>  (6)
<223>  Xaa can be Cys, D-Cys, Phe, His, Trp

<220>
<221>  misc_feature
<222>  (7)
<223>  Xaa can be Ala, Asp, Glu, His, Ile, Thr

<220>
<221>  misc_feature
<222>  (8)
<223>  Xaa can be Ala, Phe, Ile, Leu, Met, Arg, Val, 
       Trp, Tyr

<220>
<221>  misc_feature
<222>  (9)
<223>  Xaa can be Ala, Phe, His, Asn, Trp

<220>
<221>  misc_feature
<222>  (10)
<223>  Xaa can be Ala, Cys, D-Cys, Asp, His, Arg,
       Trp, Tyr

<220>
<221>  misc_feature
<222>  (11)
<223>  Xaa can be Asp, Glu, Val

<400>  1

Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa 
1               5                   10      


<210>  2
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  2

Val Cys Asn Ala Thr Cys His Ile Trp His 
1               5                   10  


<210>  3
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  3

Val Cys Asn Ala Thr Cys His Ile Trp Arg 
1               5                   10  


<210>  4
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  4

Val Trp Asn Ala Thr Cys His Ile Trp Cys 
1               5                   10  


<210>  5
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  5

Val Trp Asn Ala Thr Phe His Ile Trp His Asp 
1               5                   10      


<210>  6
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  6

Val Cys Asn Ala Cys Phe His Ile Trp His 
1               5                   10  


<210>  7
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  7

Val Trp Asn Ala Thr Phe His Ile Trp His 
1               5                   10  


<210>  8
<211>  31
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  8

Tyr Gly Arg Lys Lys Arg Arg Gln Arg Arg Arg Gly Gly Thr Asn Val 
1               5                   10                  15      


Phe Asn Ala Thr Phe Glu Ile Trp His Asp Gly Glu Phe Gly Thr 
            20                  25                  30      


<210>  9
<211>  24
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  9

Tyr Gly Arg Lys Lys Arg Arg Gln Arg Arg Arg Gly Gly Val Trp Asn 
1               5                   10                  15      


Ala Thr Phe His Ile Trp His Asp 
            20                  


<210>  10
<211>  23
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  10

Tyr Gly Arg Lys Lys Arg Arg Gln Arg Arg Arg Gly Gly Val Phe Asn 
1               5                   10                  15      


Ala Thr Phe Glu Ile Trp His 
            20              


<210>  11
<211>  13
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  11

Gly Gly Val Trp Asn Ala Thr Phe His Ile Trp His Asp 
1               5                   10              


<210>  12
<211>  13
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  12

Gly Gly Val Trp Ala Ala Thr Phe His Ile Trp His Asp 
1               5                   10              


<210>  13
<211>  13
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  13

Gly Gly Val Trp Asn Ala Ala Phe His Ile Trp His Asp 
1               5                   10              


<210>  14
<211>  13
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  14

Gly Gly Val Trp Asn Ala Thr Ala His Ile Trp His Asp 
1               5                   10              


<210>  15
<211>  13
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  15

Gly Gly Val Trp Asn Ala Thr Phe Ala Ile Trp His Asp 
1               5                   10              


<210>  16
<211>  13
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  16

Gly Gly Val Trp Asn Ala Thr Phe His Ala Trp His Asp 
1               5                   10              


<210>  17
<211>  13
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  17

Gly Gly Val Trp Asn Ala Thr Phe His Ile Ala His Asp 
1               5                   10              


<210>  18
<211>  13
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  18

Gly Gly Val Trp Asn Ala Thr Phe His Ile Trp Ala Asp 
1               5                   10              


<210>  19
<211>  13
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  19

Gly Gly Val Ala Asn Ala Thr Phe His Ile Trp His Asp 
1               5                   10              


<210>  20
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  20

Tyr Gly Arg Lys Lys Arg Arg Gln Arg Arg Arg 
1               5                   10      


<210>  21
<211>  11
<212>  PRT
<213>  Homo sapiens

<400>  21

Val Phe Asn Ala Thr Phe His Ile Trp His Ser 
1               5                   10      


<210>  22
<211>  24
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  22

Tyr Gly Arg Lys Lys Arg Arg Gln Arg Arg Arg Gly Gly Val Phe Asn 
1               5                   10                  15      


Ala Thr Phe Glu Ile Trp His Asp 
            20                  


<210>  23
<211>  31
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  23

Tyr Gly Arg Lys Lys Arg Arg Gln Arg Arg Arg Gly Gly Thr Asn Val 
1               5                   10                  15      


Phe Asn Ala Thr Phe His Ile Trp His Ser Gly Gln Phe Gly Thr 
            20                  25                  30      


<210>  24
<211>  31
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  24

Tyr Gly Arg Lys Lys Arg Arg Gln Arg Arg Arg Gly Gly Val Gly Asn 
1               5                   10                  15      


Asp Phe Phe Ile Asn His Glu Thr Thr Gly Phe Ala Thr Glu Trp 
            20                  25                  30      


<210>  25
<211>  31
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  25

Arg Arg Arg Gln Arg Arg Lys Lys Arg Gly Tyr Gly Gly Thr Gly Phe 
1               5                   10                  15      


Glu Gly Asp His Trp Ile Glu Phe Thr Ala Asn Phe Val Asn Thr 
            20                  25                  30      


<210>  26
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  26

Val Cys Asn Ala Cys Phe His Ile Trp Ala 
1               5                   10  


<210>  27
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  27

Val Cys Asn Ala Cys Phe His Ile Ala His 
1               5                   10  


<210>  28
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  28

Val Cys Asn Ala Cys Phe His Ala Trp His 
1               5                   10  


<210>  29
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  29

Val Cys Asn Ala Cys Phe Ala Ile Trp His 
1               5                   10  


<210>  30
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  30

Val Cys Asn Ala Cys Ala His Ile Trp His 
1               5                   10  


<210>  31
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  31

Ala Cys Asn Ala Cys Phe His Ile Trp His 
1               5                   10  


<210>  32
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  32

Val Trp Asn Ala Thr Phe Cys Ile Trp His Cys 
1               5                   10      


<210>  33
<211>  13
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  33

Tyr Gly Arg Lys Lys Arg Arg Gln Arg Arg Arg Gly Gly 
1               5                   10              


<210>  34
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  34

Val Phe Asn Ala Thr Phe Glu Ile Trp His Asp 
1               5                   10      


<210>  35
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  35

Cys Phe Asn Ala Thr Phe Glu Ile Trp His Asp 
1               5                   10      


<210>  36
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  36

Val Trp Asn Ala Thr Phe Glu Ile Trp His Asp 
1               5                   10      


<210>  37
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  37

Val Phe Asp Ala Thr Phe Glu Ile Trp His Asp 
1               5                   10      


<210>  38
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  38

Val Phe Asn Ser Thr Phe Glu Ile Trp His Asp 
1               5                   10      


<210>  39
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  39

Val Phe Asn Ala Cys Phe Glu Ile Trp His Asp 
1               5                   10      


<210>  40
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  40

Val Phe Asn Ala Thr Trp Glu Ile Trp His Asp 
1               5                   10      


<210>  41
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  41

Val Phe Asn Ala Thr Phe Asp Ile Trp His Asp 
1               5                   10      


<210>  42
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  42

Val Phe Asn Ala Thr Phe Glu Leu Trp His Asp 
1               5                   10      


<210>  43
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  43

Val Phe Asn Ala Thr Phe Glu Ile Phe His Asp 
1               5                   10      


<210>  44
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  44

Val Phe Asn Ala Thr Phe Glu Ile Trp Tyr Asp 
1               5                   10      


<210>  45
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  45

Val Phe Asn Ala Thr Phe Glu Ile Trp His Glu 
1               5                   10      


<210>  46
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  46

Val Trp Asn Ala Thr Phe Glu Leu Trp His Asp 
1               5                   10      


<210>  47
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  47

Val Tyr Asn Ala Thr Phe Glu Ile Trp His Asp 
1               5                   10      


<210>  48
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  48

Val Phe Asn Ala Thr Phe Glu Val Trp His Asp 
1               5                   10      


<210>  49
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  49

Val Leu Asn Ala Thr Phe Glu Ile Trp His Asp 
1               5                   10      


<210>  50
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  50

Val Phe Asn Ala Thr Phe Glu Met Trp His Asp 
1               5                   10      


<210>  51
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  51

Val Phe Asn Ala Thr Phe Glu Phe Trp His Asp 
1               5                   10      


<210>  52
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  52

Val Phe Asn Ala Thr Phe Glu Tyr Trp His Asp 
1               5                   10      


<210>  53
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  53

Val Phe Asn Ala Thr Phe Glu Arg Trp His Asp 
1               5                   10      


<210>  54
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  54

Phe Asn Ala Thr Phe Glu Ile Trp His Asp 
1               5                   10  


<210>  55
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  55

Thr Phe Asn Ala Thr Phe Glu Ile Trp His Asp 
1               5                   10      


<210>  56
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  56

Asp Phe Asn Ala Thr Phe Glu Ile Trp His Asp 
1               5                   10      


<210>  57
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  57

Gly Phe Asn Ala Thr Phe Glu Ile Trp His Asp 
1               5                   10      


<210>  58
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  58

Val Phe Asn Ala Thr Phe Glu Ile Trp His 
1               5                   10  


<210>  59
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  59

Val Trp Asn Ala Thr Phe His Tyr Trp His Asp 
1               5                   10      


<210>  60
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  60

Phe Asn Ala Thr Phe Glu Ile Trp His 
1               5                   


<210>  61
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  61

Phe Asn Ala Thr Phe His Ile Trp His 
1               5                   


<210>  62
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  62

Trp Asn Ala Thr Phe His Ile Trp His 
1               5                   


<210>  63
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  63

Trp Asn Ala Thr Phe His Ile Trp His Asp 
1               5                   10  


<210>  64
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  64

Trp Asn Ala Thr Phe His Ile Trp 
1               5               


<210>  65
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  65

Val Trp Ala Ala Thr Phe His Ile Trp His Asp 
1               5                   10      


<210>  66
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  66

Val Trp Asn Ala Ala Phe His Ile Trp His Asp 
1               5                   10      


<210>  67
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  67

Val Trp Asn Ala Thr Ala His Ile Trp His Asp 
1               5                   10      


<210>  68
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  68

Val Trp Asn Ala Thr Phe Ala Ile Trp His Asp 
1               5                   10      


<210>  69
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  69

Val Trp Asn Ala Thr Phe His Ala Trp His Asp 
1               5                   10      


<210>  70
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  70

Val Trp Asn Ala Thr Phe His Ile Ala His Asp 
1               5                   10      


<210>  71
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  71

Val Trp Asn Ala Thr Phe His Ile Trp Ala Asp 
1               5                   10      


<210>  72
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  72

Val Ala Asn Ala Thr Phe His Ile Trp His Asp 
1               5                   10      


<210>  73
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  73

Asn Ala Thr Phe His Ile Trp 
1               5           


<210>  74
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  74

Trp Asn Ala Thr Phe His Ile 
1               5           


<210>  75
<211>  12
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Description of Artificial Sequence: Synthetic

       polypeptide

<400>  75

Val Cys Asn Ala Thr Cys His Ile Arg Ile Trp His 
1               5                   10          


