                         SEQUENCE LISTING

<110>  H. Lee Moffitt Cancer Center and Research Institute, Inc.
 
<120>  TLR9 TARGETED THERAPEUTICS

<130>  320803-2080

<150>  US 62/370,428
<151>  2016-08-03

<160>  64    

<170>  PatentIn version 3.5

<210>  1
<211>  18
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  1

Lys Ala Phe Lys Lys Ala Phe Lys Ala Phe Lys Lys Ala Phe Lys Ala 
1               5                   10                  15      


Phe Lys 
        


<210>  2
<211>  18
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Postive charge amino acid

<220>
<221>  MISC_FEATURE
<222>  (2)..(3)
<223>  hydrophobic amino acid

<220>
<221>  MISC_FEATURE
<222>  (4)..(5)
<223>  Postive charge amino acid

<220>
<221>  MISC_FEATURE
<222>  (6)..(7)
<223>  hydrophobic amino acid

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Postive charge amino acid

<220>
<221>  MISC_FEATURE
<222>  (9)..(10)
<223>  hydrophobic amino acid

<220>
<221>  MISC_FEATURE
<222>  (11)..(12)
<223>  Postive charge amino acid

<220>
<221>  MISC_FEATURE
<222>  (13)..(14)
<223>  hydrophobic amino acid

<220>
<221>  MISC_FEATURE
<222>  (15)..(15)
<223>  Postive charge amino acid

<220>
<221>  MISC_FEATURE
<222>  (16)..(17)
<223>  hydrophobic amino acid

<220>
<221>  MISC_FEATURE
<222>  (18)..(18)
<223>  Postive charge amino acid

<400>  2

Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa 
1               5                   10                  15      


Xaa Xaa 
        


<210>  3
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  3
tccatgacgt tcctgatgct                                                   20


<210>  4
<211>  24
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  4
tcgtcgtttt gtcgttttgt cgtt                                              24


<210>  5
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  5
tccatgacgt tcctgacgtt                                                   20


<210>  6
<211>  21
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  6
ggggacgacg tcgtgggggg g                                                 21


<210>  7
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  7
gggggacgat cgtcgggggg                                                   20


<210>  8
<211>  22
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  8
tcgtcgttgt cgttttgtcg tt                                                22


<210>  9
<211>  23
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  9
tcgacgttcg tcgttcgtcg ttc                                               23


<210>  10
<211>  26
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  10
tcgcgacgtt cgcccgacgt tcggta                                            26


<210>  11
<211>  22
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  11
tcgtcgtttt cggcgcgcgc cg                                                22


<210>  12
<211>  25
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  12
tcgtcgtcgt tcgaacgacg ttgat                                             25


<210>  13
<211>  29
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  13
tcgcgaacgt tcgccgcgtt cgaacgcgg                                         29


<210>  14
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  misc_feature
<222>  (1)..(20)
<223>  Phophorothioate bond

<400>  14
tccatgacgt tcctgatgct                                                   20


<210>  15
<211>  21
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  misc_feature
<222>  (1)..(3)
<223>  Phosphorothioate bond

<220>
<221>  misc_feature
<222>  (16)..(21)
<223>  Phosphorothioate bond

<400>  15
ggggacgacg tcgtgggggg g                                                 21


<210>  16
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  Phosphorothiate bond

<220>
<221>  misc_feature
<222>  (15)..(20)
<223>  Phosphorothiate bond

<400>  16
gggggacgat cgtcgggggg                                                   20


<210>  17
<211>  25
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  misc_feature
<222>  (1)..(25)
<223>  Phosphorothioate bond

<400>  17
tcgtcgtcgt tcgaacgacg ttgat                                             25


<210>  18
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  18

Lys Ile Lys Met Val Ile Ser Trp Lys Gly 
1               5                   10  


<210>  19
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  19

Ala Ile Ala Met Val Ile Ser Trp Ala Gly 
1               5                   10  


<210>  20
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  20

Ala Ile Lys Met Val Ile Ser Trp Ala Gly 
1               5                   10  


<210>  21
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  21

Ala Ile Lys Met Val Ile Ser Trp Lys Gly 
1               5                   10  


<210>  22
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  22

Ala Lys Met Val Ile Ser Trp 
1               5           


<210>  23
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  23

Ala Lys Met Val Leu Ser Trp Lys Gly 
1               5                   


<210>  24
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  24

Ile Ala Met Val Ile Ser Trp 
1               5           


<210>  25
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  25

Ile Ala Met Val Ile Ser Trp Lys Gly 
1               5                   


<210>  26
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  26

Ile Lys Ala Val Ile Ser Trp 
1               5           


<210>  27
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  27

Ile Lys Ala Val Ile Ser Trp Lys Gly 
1               5                   


<210>  28
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  28

Ile Lys Met Ala Ile Ser Trp 
1               5           


<210>  29
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  29

Ile Lys Met Ala Ile Ser Trp Lys Gly 
1               5                   


<210>  30
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  30

Ile Lys Met Val Ala Ser Trp 
1               5           


<210>  31
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  31

Ile Lys Met Val Ala Ser Trp Lys Gly 
1               5                   


<210>  32
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  32

Ile Lys Met Val Ile Ala Trp 
1               5           


<210>  33
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  33

Ile Lys Met Val Ile Ala Trp Lys Gly 
1               5                   


<210>  34
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  34

Ile Lys Met Val Ile Ser Ala 
1               5           


<210>  35
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  35

Ile Lys Met Val Ile Ser Ala Lys Gly 
1               5                   


<210>  36
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  36

Ile Lys Met Val Ile Ser Trp 
1               5           


<210>  37
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  37

Ile Lys Met Val Ile Ser Trp Ala Gly 
1               5                   


<210>  38
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  38

Lys Met Val Ile Ser Trp Lys Ala 
1               5               


<210>  39
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  39

Ile Lys Met Val Ile Ser Trp Lys Gly 
1               5                   


<210>  40
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  40

Ile Ser Trp Lys Gly 
1               5   


<210>  41
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  41

Lys Ala Lys Met Val Ile Ser Trp Lys Gly 
1               5                   10  


<210>  42
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  42

Lys Ile Ala Met Val Ile Ser Trp Ala Gly 
1               5                   10  


<210>  43
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  43

Lys Ile Ala Met Val Ile Ser Trp Lys Gly 
1               5                   10  


<210>  44
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  44

Lys Ile Lys Ala Val Ile Ser Trp Lys Gly 
1               5                   10  


<210>  45
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  45

Lys Ile Lys Met Ala Ile Ser Trp Lys Gly 
1               5                   10  


<210>  46
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  46

Lys Ile Lys Met Val 
1               5   


<210>  47
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  47

Lys Ile Lys Met Val Ala Ser Trp Lys Gly 
1               5                   10  


<210>  48
<211>  6
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  48

Lys Ile Lys Met Val Ile 
1               5       


<210>  49
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  49

Lys Ile Lys Met Val Ile Ala 
1               5           


<210>  50
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  50

Lys Ile Lys Met Val Ile Ser 
1               5           


<210>  51
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  51

Lys Ile Lys Met Val Ile Ser Ala Lys Gly 
1               5                   10  


<210>  52
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  52

Lys Ile Lys Met Val Ile Ser Trp 
1               5               


<210>  53
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  53

Lys Ile Lys Met Val Ile Ser Trp Ala Gly 
1               5                   10  


<210>  54
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  54

Lys Ile Lys Met Val Ile Ser Trp Lys 
1               5                   


<210>  55
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  55

Lys Ile Lys Met Val Ile Ser Trp Lys Ala 
1               5                   10  


<210>  56
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  56

Lys Met Val Ile Ser Trp Lys Gly 
1               5               


<210>  57
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  57

Leu Ser Trp Lys Gly 
1               5   


<210>  58
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  58

Met Val Ile Ser Trp Lys Gly 
1               5           


<210>  59
<211>  4
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  59

Ser Trp Lys Gly 
1               


<210>  60
<211>  6
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  60

Val Ile Ser Trp Lys Gly 
1               5       


<210>  61
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  61

Trp Ile Lys Ser Met Lys Ile Val Lys Gly 
1               5                   10  


<210>  62
<211>  6
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (5)..(5)
<223>  Xaa is any amino acid

<400>  62

Lys Met Val Ile Xaa Trp 
1               5       


<210>  63
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (8)..(9)
<223>  Xaa is any amino acid

<400>  63

Ile Lys Met Val Ile Ser Trp Xaa Xaa 
1               5                   


<210>  64
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (7)..(8)
<223>  Xaa is any amino acid

<400>  64

Lys Met Val Ile Ser Trp Xaa Xaa 
1               5               


