                         SEQUENCE LISTING

<110>  Novartis AG
       Hao, Huaixiang
       LaMarche , Matthew  J
       Li, Fang
       Wang, Hui-Qin
       Alghalandis, Leila Dardaei
       Engelman, Jeffrey A
 
<120>  Pharmaceutical Combinations

<130>  PAT057571-WO-PCT

<160>  1     

<170>  PatentIn version 3.5

<210>  1
<211>  20
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  biphosphorylated peptide derived from insulin receptor 
       substrate-1 (IRS-1)


<220>
<221>  MOD_RES
<222>  (3)..(3)
<223>  PHOSPHORYLATED TYROSINE

<220>
<221>  MOD_RES
<222>  (9)..(10)
<223>  Pegylated (dPEG8) between valine residue 9 and leucine residue 10

<220>
<221>  MOD_RES
<222>  (13)..(13)
<223>  PHOSPHORYLATED TYROSINE

<220>
<221>  MOD_RES
<222>  (20)..(20)
<223>  AMIDATED Lysine

<400>  1

Leu Asn Tyr Ile Asp Leu Asp Leu Val Leu Ser Thr Tyr Ala Ser Ile 
1               5                   10                  15      


Asn Phe Gln Lys 
            20  


