                         SEQUENCE LISTING

<110>  aratinga.bio
 
<120>  Enhancement of Biologics Production in Cell Culture Systems by 
       Fertilin-Derived Peptides

<130>  320546-00021

<140>  PCT/US18/61393
<141>  2018-11-15

<150>  US 62/588,244
<151>  2017-11-15

<160>  9     

<170>  PatentIn version 3.5

<210>  1
<211>  30
<212>  PRT
<213>  Homo sapiens

<400>  1

Cys Leu Phe Met Ser Lys Glu Arg Met Cys Arg Pro Ser Phe Glu Glu 
1               5                   10                  15      


Cys Asp Leu Pro Glu Tyr Cys Asn Gly Ser Ser Ala Ser Cys 
            20                  25                  30  


<210>  2
<211>  30
<212>  PRT
<213>  Mus musculus

<400>  2

Cys Lys Leu Lys Arg Lys Gly Glu Val Cys Arg Leu Ala Gln Asp Glu 
1               5                   10                  15      


Cys Asp Val Thr Glu Tyr Cys Asn Gly Thr Ser Glu Val Cys 
            20                  25                  30  


<210>  3
<211>  30
<212>  PRT
<213>  Cavia porcellus

<400>  3

Cys Glu Phe Lys Thr Lys Gly Glu Val Cys Arg Glu Ser Thr Asp Glu 
1               5                   10                  15      


Cys Asp Leu Pro Glu Tyr Cys Asn Gly Ser Ser Gly Ala Cys 
            20                  25                  30  


<210>  4
<211>  30
<212>  PRT
<213>  Macaca fascicularis

<400>  4

Cys Leu Phe Met Ser Gln Glu Arg Val Cys Arg Pro Ser Phe Asp Glu 
1               5                   10                  15      


Cys Asp Leu Pro Glu Tyr Cys Asn Gly Thr Ser Ala Ser Cys 
            20                  25                  30  


<210>  5
<211>  30
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  5

Cys Thr Phe Lys Glu Lys Gly Gln Ser Cys Arg Pro Pro Val Gly Glu 
1               5                   10                  15      


Cys Asp Leu Phe Glu Tyr Cys Asn Gly Thr Ser Ala Leu Cys 
            20                  25                  30  


<210>  6
<211>  30
<212>  PRT
<213>  rattus rattus

<400>  6

Cys Asn Leu Lys Ala Lys Gly Glu Leu Cys Arg Pro Ala Asn Gln Glu 
1               5                   10                  15      


Cys Asp Val Thr Glu Tyr Cys Asn Gly Thr Ser Glu Val Cys 
            20                  25                  30  


<210>  7
<211>  30
<212>  PRT
<213>  Artificial sequence

<220>
<223>  Consensus sequence for fertilin fragment


<220>
<221>  misc_feature
<222>  (2)..(9)
<223>  Xaa can be any naturally occurring amino acid

<220>
<221>  misc_feature
<222>  (12)..(16)
<223>  Xaa can be any naturally occurring amino acid

<220>
<221>  misc_feature
<222>  (19)..(20)
<223>  Xaa can be any naturally occurring amino acid

<220>
<221>  misc_feature
<222>  (25)..(26)
<223>  Xaa can be any naturally occurring amino acid

<220>
<221>  misc_feature
<222>  (28)..(29)
<223>  Xaa can be any naturally occurring amino acid

<400>  7

Cys Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Cys Arg Xaa Xaa Xaa Xaa Xaa 
1               5                   10                  15      


Cys Asp Xaa Xaa Glu Tyr Cys Asn Xaa Xaa Ser Xaa Xaa Cys 
            20                  25                  30  


<210>  8
<211>  6
<212>  PRT
<213>  Artificial sequence

<220>
<223>  Cyclic peptide with disulfide bond between positions 1 and 6; 
       fertilin analog

<400>  8

Cys Ser Phe Glu Glu Cys 
1               5       


<210>  9
<211>  7
<212>  PRT
<213>  Artificial sequence

<220>
<223>  Cyclic peptide with disulfide bond between residues 1 and 7; 
       fertilin analog


<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  Xaa can be any naturally occurring amino acid

<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  Xaa can be any naturally occurring amino acid

<400>  9

Cys Xaa Phe Glu Glu Xaa Cys 
1               5           


