                         SEQUENCE LISTING

<110>  The Regents of the University of California
 
<120>  Inhibition of FSP1 Activity to Induce Ferroptosis

<130>  034044.199WO1

<150>  62/828,662
<151>  2019-04-03

<160>  11    

<170>  PatentIn version 3.5

<210>  1
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Consensus myristoylation motif in FSP1


<220>
<221>  MISC_FEATURE
<222>  (3)..(5)
<223>  Wherein each Xaa are independently any amino acid residue.

<220>
<221>  MISC_FEATURE
<222>  (7)..(10)
<223>  Wherein each Xaa are independently any amino acid residue.

<400>  1

Met Gly Xaa Xaa Xaa Ser Xaa Xaa Xaa Xaa 
1               5                   10  


<210>  2
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Myristoylation motif in FSP1

<400>  2

Met Gly Ser Gln Val Ser Val Glu Ser Gly 
1               5                   10  


<210>  3
<211>  16
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  AIF partial sequence

<400>  3

Ile Thr Val Ile Gly Gly Gly Phe Leu Gly Ser Glu Leu Ala Cys Ala 
1               5                   10                  15      


<210>  4
<211>  16
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  FSP1 partial sequence

<400>  4

Ile Val Val Val Gly Gly Gly Ser Ala Gly Val Glu Met Ala Ala Glu 
1               5                   10                  15      


<210>  5
<211>  24
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  FSP1 guide 1

<400>  5
caccggaatc gggagctctg cacg                                              24


<210>  6
<211>  25
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  FSP1 guide 2

<400>  6
caccgtcccg attccaccga gacct                                             25


<210>  7
<211>  25
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  ACSL4 guide 1

<400>  7
caccgtgcaa tcatccattc ggccc                                             25


<210>  8
<211>  25
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  ACSL4 guide 2

<400>  8
caccgtggta gtggactcac tgcac                                             25


<210>  9
<211>  25
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  NQO1 guide 1

<400>  9
caccgtttgc agcactcacc gacca                                             25


<210>  10
<211>  25
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  NQO1 guide 2

<400>  10
caccgcagaa gagcactgat cgtac                                             25


<210>  11
<211>  25
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  GPX4 guide

<400>  11
caccgagccc cgccgcgatg agcct                                             25


