                               SEQUENCE LISTING

<110> FLAGSHIP PIONEERING INNOVATIONS VI, LLC
 
<120> COMPOSITIONS COMPRISING CIRCULAR POLYRIBONUCLEOTIDES FOR PROTEIN 
      MODULATION AND USES THEREOF

<130> 55503-707.601

<140> PCT/US2020/038838
<141> 2020-06-19

<150> 62/878,220
<151> 2019-07-24

<150> 62/863,698
<151> 2019-06-19

<160> 17    

<170> PatentIn version 3.5

<210> 1
<211> 264
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polynucleotide"

<400> 1
gggagccacc atggactaca aggacgacga cgacaagatc atcgactata aagacgacga       60

cgataaaggt ggcgactata aggacgacga cgacaaagcc attaatagtg actctgagtg      120

tcccctgtcc cacgacgggt actgcctcca cgacggtgtg tgcatgtata ttgaagcatt      180

ggacaagtac gcctgcaact gtgttgttgg ctacatcggg gagcgctgtc agtaccgaga      240

cctgaagtgg tgggaacagc gcca                                             264


<210> 2
<211> 90
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 2
ggaacggcaa ccgggcaaac aaacaatcaa tcaatcaatc aatcaatcaa tcaatcaatc       60

aatcaaacaa acaaaagacc gagagccacc                                        90


<210> 3
<211> 70
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 3
ggaatagccg aaaaacaaaa agatcttgaa actgttttaa ggttggccga tcaaaaacaa       60

aacggctatt                                                              70


<210> 4
<211> 8
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> VARIANT
<222> (2)..(2)
<223> /replace="Ile"

<220>
<221> MOD_RES
<222> (4)..(4)
<223> Any amino acid

<220>
<221> SITE
<222> (1)..(8)
<223> /note="Variant residues given in the sequence have no 
      preference with respect to those in the annotations
      for variant positions"

<400> 4
Asp Val Glu Xaa Asn Pro Gly Pro 
1               5               


<210> 5
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      primer"

<400> 5
tacgcctgca actgtgttgt                                                   20


<210> 6
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      primer"

<400> 6
tcgatgatct tgtcgtcgtc                                                   20


<210> 7
<211> 51
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 7
ucauaaucaa uuuauuauuu ucuuuuauuu uauucacaua auuuuguuuu u                51


<210> 8
<211> 19
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 8
auuuuguuuu uaacauuuc                                                    19


<210> 9
<211> 70
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 9
ucauaaucaa uuuauuauuu ucuuuuauuu uauucacaua auuuuguuuu uauuuuguuu       60

uuaacauuuc                                                              70


<210> 10
<211> 119
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polynucleotide"

<400> 10
caauaaugga ggcaauggua ugacuccaag ugcuauuguc acagaugaaa uuggcaguau       60

ugaccuuaua cuaaaaggca gggguuaaaa augauuauau acauuuuccu uaaaacacu       119


<210> 11
<211> 49
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 11
aaaaaaaaaa gatcttgaaa ctgttttaag gttggccgat cttaaaaaa                   49


<210> 12
<211> 60
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 12
aaaaaaattc tccgaacgtg tcacgtttca agagaacgtg acacgttcgg agaaaaaaaa       60


<210> 13
<211> 232
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polynucleotide"

<220>
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      polynucleotide"

<400> 13
aatagccggu cuacggccau accacccuga acgcgcccga ucucgucuga ucucggaagc       60

uaagcagggu cgggccuggu uaguacuugg augggagacc gccugggaau accgggugcu      120

guaggcgucg acuugccaug uguauguggg uacgaaggaa ggauugguau gugguauauu      180

cguacccaca uacucugaug auccuucggg aucauucaug gcaacggcta tt              232


<210> 14
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 14
cgagacgcta cggacttaaa atccgttgac                                        30


<210> 15
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 15
ggtggctccc tggcgctgtt                                                   20


<210> 16
<211> 28
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 16
cccggttgcc gttccaatag ccgttttg                                          28


<210> 17
<211> 31
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 17
gtttttcggc tattccggtg gctctcggtc t                                      31


