               SEQUENCE LISTING

<110> Theraxen S.A.

<120> Xeno-nucleotide based branched DNA assay for the detection of nucleic acids

<130> AD2097 PCT S3

<150> EP20 18 9484.7
<151> 2020-08-04

<160> 46

<170> BiSSAP 1.3.6

<210> 1
<211> 10
<212> RNA
<213> Artificial Sequence


<220> 
<223> CE2 sequence, composed of xylonucleic acid

<220> 
<221> modified_base
<222> 1..10
<223> /mod_base="OTHER"
      /note="xylonucleotides"

<400> 1
guaccgauug                                                           10


<210> 2
<211> 10
<212> RNA
<213> Artificial Sequence


<220> 
<223> CP1 sequence, composed of xylonucleic acid

<220> 
<221> modified_base
<222> 1..10
<223> /mod_base="OTHER"
      /note="xylonucleotides"

<400> 2
caaucgguac                                                           10


<210> 3
<211> 12
<212> DNA
<213> Artificial Sequence


<220> 
<223> Hexitol nucleic acid sequence used in Example 1

<220> 
<221> modified_base
<222> 1..12
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 3
agggagagga ga                                                        12


<210> 4
<211> 12
<212> RNA
<213> Artificial Sequence


<220> 
<223> Complementary RNA sequence used in Example 1

<400> 4
ucuccucucc cu                                                        12


<210> 5
<211> 12
<212> DNA
<213> Artificial Sequence


<220> 
<223> DNA sequence used in Example 1

<400> 5
agggagagga ga                                                        12


<210> 6
<211> 12
<212> RNA
<213> Artificial Sequence


<220> 
<223> CP1 sequence, composed of xylonucleic acid

<220> 
<221> modified_base
<222> 1..12
<223> /mod_base="OTHER"
      /note="xylonucleotides"

<400> 6
aaugcugacu ca                                                        12


<210> 7
<211> 20
<212> DNA
<213> Artificial Sequence


<220> 
<223> /note="combined DNA/RNA molecule"
      /note="Capture probe sequence"

<220> 
<221> modified_base
<222> 9..20
<223> /mod_base="OTHER"
      /note="xylonucleotides"

<400> 7
ttttttttaa ugcugacuca                                                20


<210> 8
<211> 15
<212> DNA
<213> Artificial Sequence


<220> 
<223> CE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..15
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 8
caattctctt tttga                                                     15


<210> 9
<211> 14
<212> DNA
<213> Artificial Sequence


<220> 
<223> CE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..14
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 9
cgggccgatt gatc                                                      14


<210> 10
<211> 14
<212> DNA
<213> Artificial Sequence


<220> 
<223> CE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..14
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 10
cagatagatg ggct                                                      14


<210> 11
<211> 13
<212> DNA
<213> Artificial Sequence


<220> 
<223> CE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..13
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 11
gtaggagacg gcg                                                       13


<210> 12
<211> 14
<212> DNA
<213> Artificial Sequence


<220> 
<223> CE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..14
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 12
ctgccccttc agct                                                      14


<210> 13
<211> 15
<212> DNA
<213> Artificial Sequence


<220> 
<223> CE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..15
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 13
agatgatctg actgc                                                     15


<210> 14
<211> 12
<212> RNA
<213> Artificial Sequence


<220> 
<223> CE2 sequence, composed of xylonucleic acid

<220> 
<221> modified_base
<222> 1..12
<223> /mod_base="OTHER"
      /note="xylonucleotides"

<400> 14
ugagucagca uu                                                        12


<210> 15
<211> 13
<212> DNA
<213> Artificial Sequence


<220> 
<223> LE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..13
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 15
gcttgggttc cga                                                       13


<210> 16
<211> 13
<212> DNA
<213> Artificial Sequence


<220> 
<223> LE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..13
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 16
cagaagaggt tga                                                       13


<210> 17
<211> 14
<212> DNA
<213> Artificial Sequence


<220> 
<223> LE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..14
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 17
tcctcacagg gcaa                                                      14


<210> 18
<211> 13
<212> DNA
<213> Artificial Sequence


<220> 
<223> LE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..13
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 18
caaagagacc tgc                                                       13


<210> 19
<211> 15
<212> DNA
<213> Artificial Sequence


<220> 
<223> LE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..15
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 19
ctcggcaaag tcgag                                                     15


<210> 20
<211> 14
<212> DNA
<213> Artificial Sequence


<220> 
<223> LE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..14
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 20
ctgagtcggt cacc                                                      14


<210> 21
<211> 15
<212> DNA
<213> Artificial Sequence


<220> 
<223> LE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..15
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 21
tccagctgga agacc                                                     15


<210> 22
<211> 12
<212> DNA
<213> Artificial Sequence


<220> 
<223> LE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..12
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 22
gggcttggcc tc                                                        12


<210> 23
<211> 15
<212> DNA
<213> Artificial Sequence


<220> 
<223> LE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..15
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 23
gagaggaggt tgacc                                                     15


<210> 24
<211> 13
<212> DNA
<213> Artificial Sequence


<220> 
<223> LE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..13
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 24
ggctgatggt gtg                                                       13


<210> 25
<211> 14
<212> DNA
<213> Artificial Sequence


<220> 
<223> LE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..14
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 25
gagcacatgg gtgg                                                      14


<210> 26
<211> 15
<212> DNA
<213> Artificial Sequence


<220> 
<223> LE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..15
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 26
aggtacaggc cctct                                                     15


<210> 27
<211> 15
<212> DNA
<213> Artificial Sequence


<220> 
<223> LE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..15
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 27
caccagctgg ttatc                                                     15


<210> 28
<211> 13
<212> DNA
<213> Artificial Sequence


<220> 
<223> LE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..13
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 28
agctccacgc cat                                                       13


<210> 29
<211> 14
<212> DNA
<213> Artificial Sequence


<220> 
<223> LE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..14
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 29
gagggcattg gccc                                                      14


<210> 30
<211> 14
<212> DNA
<213> Artificial Sequence


<220> 
<223> LE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..14
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 30
ggttcagcca ctgg                                                      14


<210> 31
<211> 15
<212> DNA
<213> Artificial Sequence


<220> 
<223> LE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..15
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 31
tgctacaaca tgggc                                                     15


<210> 32
<211> 15
<212> DNA
<213> Artificial Sequence


<220> 
<223> LE1 sequence, composed of hexitol nucleic acid

<220> 
<221> modified_base
<222> 1..15
<223> /mod_base="OTHER"
      /note="hexitol nucleotides"

<400> 32
actccaaagt gcagc                                                     15


<210> 33
<211> 15
<212> RNA
<213> Artificial Sequence


<220> 
<223> LE2 sequence, composed of xylonucleic acid

<220> 
<221> modified_base
<222> 1..15
<223> /mod_base="OTHER"
      /note="xylonucleotides"

<400> 33
guaugcgcug cuaug                                                     15


<210> 34
<211> 21
<212> DNA
<213> Artificial Sequence


<220> 
<223> Blocking probe sequence

<400> 34
aggagggggt aataaaggga t                                              21


<210> 35
<211> 15
<212> DNA
<213> Artificial Sequence


<220> 
<223> Blocking probe sequence

<400> 35
tggggcaggg gaggc                                                     15


<210> 36
<211> 21
<212> DNA
<213> Artificial Sequence


<220> 
<223> Blocking probe sequence

<400> 36
gtttgcgaag gttggatgtt c                                              21


<210> 37
<211> 19
<212> DNA
<213> Artificial Sequence


<220> 
<223> Blocking probe sequence

<400> 37
cccctctggg gtctccctc                                                 19


<210> 38
<211> 18
<212> DNA
<213> Artificial Sequence


<220> 
<223> Blocking probe sequence

<400> 38
tggcaggggc tcttgatg                                                  18


<210> 39
<211> 16
<212> DNA
<213> Artificial Sequence


<220> 
<223> Blocking probe sequence

<400> 39
gggcagcctt ggccct                                                    16


<210> 40
<211> 23
<212> DNA
<213> Artificial Sequence


<220> 
<223> Blocking probe sequence

<400> 40
tgaagaggac ctgggagtag atg                                            23


<210> 41
<211> 19
<212> DNA
<213> Artificial Sequence


<220> 
<223> Blocking probe sequence

<400> 41
aggcttgtca ctcggggtt                                                 19


<210> 42
<211> 21
<212> DNA
<213> Artificial Sequence


<220> 
<223> Blocking probe sequence

<400> 42
ggccagaggg ctgattagag a                                              21


<210> 43
<211> 20
<212> DNA
<213> Artificial Sequence


<220> 
<223> Blocking probe sequence

<400> 43
gaggtccctg gggaactctt                                                20


<210> 44
<211> 15
<212> DNA
<213> Artificial Sequence


<220> 
<223> Blocking probe sequence

<400> 44
ccctctgggg gccga                                                     15


<210> 45
<211> 12
<212> RNA
<213> Artificial Sequence


<220> 
<223> Preamplifier PA1 sequence, composed of xylonucleic acid

<220> 
<221> modified_base
<222> 1..12
<223> /mod_base="OTHER"
      /note="xylonucleotides"

<400> 45
cggcccuagg ca                                                        12


<210> 46
<211> 12
<212> RNA
<213> Artificial Sequence


<220> 
<223> Amplifier repeat sequence, composed of xylonucleic acid

<220> 
<221> modified_base
<222> 1..12
<223> /mod_base="OTHER"
      /note="xylonucleotides"

<400> 46
cguaccaagu gc                                                        12


